From 1127ba744c76e9f2fb38632e3a14fd271c5421a9 Mon Sep 17 00:00:00 2001 From: Qing Date: Tue, 20 Aug 2024 23:10:37 -0400 Subject: [PATCH 1/7] - New: Added a option to split the items contain multiple functions to multiple items when set OTF table. --- Docs/ChangeLog.md | 6 + Docs/MetaX_Cookbook.md | 2 +- README.md | 2 +- metax/gui/main_gui.py | 7 +- metax/gui/metax_gui/main_window.ui | 739 +++++++++++++++----------- metax/gui/metax_gui/ui_main_window.py | 282 +++++----- metax/taxafunc_analyzer/analyzer.py | 144 +++-- metax/utils/version.py | 2 +- pyproject.toml | 2 +- 9 files changed, 693 insertions(+), 493 deletions(-) diff --git a/Docs/ChangeLog.md b/Docs/ChangeLog.md index d1f9234..14f4e53 100644 --- a/Docs/ChangeLog.md +++ b/Docs/ChangeLog.md @@ -1,3 +1,9 @@ +# Version: 1.111.0 +## Date: 2024-08-20 +### Changes: +- New: Added a option to split the items contain multiple functions to multiple items when set OTF table. + + # Version: 1.110.1 ## Date: 2024-08-20 ### Changes: diff --git a/Docs/MetaX_Cookbook.md b/Docs/MetaX_Cookbook.md index 00a8dff..214706f 100644 --- a/Docs/MetaX_Cookbook.md +++ b/Docs/MetaX_Cookbook.md @@ -4,7 +4,7 @@ This is the guidebook for the MetaX **GUI Version**. If you are using the CLI to # Overview -**[MetaX](https://github.com/byemaxx/MetaX)** is a novel tool for linking peptide sequences with taxonomic and functional information in **Metaproteomics**. We introduce the ***Operational Taxa-Functions (OTF)*** concept to explore microbial roles and interactions ("**who is doing what and how**") within ecosystems. +**[MetaX](https://github.com/byemaxx/MetaX)** is a novel tool for linking peptide sequences with taxonomic and functional information in **Metaproteomics**. We introduce the ***Operational Taxon-Function (OTF)*** concept to explore microbial roles and interactions ("**who is doing what and how**") within ecosystems. MetaX also features statistical modules and plotting tools for analyzing peptides, taxa, functions, proteins, and taxon-function contributions across groups. diff --git a/README.md b/README.md index 9293b28..35ec7da 100644 --- a/README.md +++ b/README.md @@ -1,6 +1,6 @@ # MetaX -**MetaX** is a novel tool for linking peptide sequences with taxonomic and functional information in **Metaproteomics**. We introduce the ***Operational Taxa-Functions (OTF)*** concept to explore microbial roles and interactions ("**who is doing what and how**") within ecosystems. +**MetaX** is a novel tool for linking peptide sequences with taxonomic and functional information in **Metaproteomics**. We introduce the ***Operational Taxon-Function (OTF)*** concept to explore microbial roles and interactions ("**who is doing what and how**") within ecosystems. MetaX also features statistical modules and plotting tools for analyzing peptides, taxa, functions, proteins, and taxon-function contributions across groups. diff --git a/metax/gui/main_gui.py b/metax/gui/main_gui.py index 771f677..be063e5 100644 --- a/metax/gui/main_gui.py +++ b/metax/gui/main_gui.py @@ -2452,6 +2452,10 @@ def set_multi_table(self, restore_taxafunc=False, saved_obj=None): func_threshold = self.doubleSpinBox_func_threshold.value() func_threshold = round(func_threshold, 3) + split_func = self.checkBox_set_taxa_func_split_func.isChecked() + split_func_params: dict = {'split_by': self.lineEdit_set_taxa_func_split_func_sep.text(), + 'share_intensity': self.checkBox_set_taxa_func_split_func_share_intensity.isChecked()} + peptide_num_threshold = { 'taxa': self.spinBox_peptide_num_threshold_taxa.value(), 'func': self.spinBox_peptide_num_threshold_func.value(), @@ -2602,7 +2606,8 @@ def set_multi_table(self, restore_taxafunc=False, saved_obj=None): 'processing_after_sum': processing_after_sum, 'peptide_num_threshold': peptide_num_threshold, 'sum_protein': sum_protein, 'sum_protein_params': sum_protein_params, - 'keep_unknow_func': False} + 'keep_unknow_func': False, + 'split_func': split_func, 'split_func_params': split_func_params} def callback_after_set_multi_tables(result, success): if success: diff --git a/metax/gui/metax_gui/main_window.ui b/metax/gui/metax_gui/main_window.ui index 89ef6c9..f266400 100644 --- a/metax/gui/metax_gui/main_window.ui +++ b/metax/gui/metax_gui/main_window.ui @@ -46,7 +46,7 @@ Qt::LeftToRight - 6 + 2 false @@ -245,8 +245,8 @@ 0 0 - 391 - 80 + 528 + 569 @@ -476,217 +476,6 @@ Set TaxaFunc - - - - - - Peptide Number Threshold - - - - - - - - 0 - 0 - - - - Qt::LeftToRight - - - - - - - - - Taxa - - - Qt::AlignCenter - - - - - - - 1 - - - 999 - - - - - - - Func - - - Qt::AlignCenter - - - - - - - 1 - - - 999 - - - - - - - Taxa-Func - - - Qt::AlignCenter - - - - - - - 1 - - - 999 - - - - - - - - - - 0 - 0 - - - - Function Filter Threshold - - - - - - - - 0 - 0 - - - - 3 - - - 1.000000000000000 - - - 0.050000000000000 - - - 1.000000000000000 - - - - - - - Qt::LeftToRight - - - Genome - - - - Genome - - - - - Species - - - - - Genus - - - - - Family - - - - - Order - - - - - Class - - - - - Phylum - - - - - Domain - - - - - Life - - - - - - - - - 0 - 0 - - - - Function - - - - - - - - 0 - 0 - - - - ? - - - - - - - Taxa Level - - - - - @@ -779,16 +568,6 @@ - - - - false - - - Inference by each Sample - - - @@ -811,6 +590,16 @@ + + + + false + + + Inference by each Sample + + + @@ -1316,6 +1105,276 @@ + + + + + + Peptide Number Threshold + + + + + + + Taxa Level + + + + + + + + 0 + 0 + + + + Function + + + + + + + + + + 0 + 0 + + + + ? + + + + + + + + 0 + 0 + + + + 3 + + + 1.000000000000000 + + + 0.050000000000000 + + + 1.000000000000000 + + + + + + + + + Qt::LeftToRight + + + Genome + + + + Genome + + + + + Species + + + + + Genus + + + + + Family + + + + + Order + + + + + Class + + + + + Phylum + + + + + Domain + + + + + Life + + + + + + + + + 0 + 0 + + + + Qt::LeftToRight + + + + + + + + 0 + 0 + + + + Function Filter Threshold + + + + + + + + + Taxa + + + Qt::AlignCenter + + + + + + + 1 + + + 999 + + + + + + + Func + + + Qt::AlignCenter + + + + + + + 1 + + + 999 + + + + + + + Taxa-Func + + + Qt::AlignCenter + + + + + + + 1 + + + 999 + + + + + + + + + + + Split items that contain multiple functions + + + Split Functions By + + + + + + + false + + + + 0 + 0 + + + + + 50 + 16777215 + + + + Separator between multiple functions + + + ; + + + Qt::AlignCenter + + + + + + + false + + + YES: Each function shares the average Intensity after splitting. NO: Every function gives the original Intensity value after splitting. + + + Share Intensty + + + + + + + @@ -3674,7 +3733,7 @@ 0 0 - 929 + 1020 126 @@ -5542,8 +5601,8 @@ 0 0 - 535 - 94 + 996 + 140 @@ -6093,8 +6152,8 @@ 0 0 - 493 - 128 + 1016 + 179 @@ -10283,12 +10342,12 @@ setEnabled(bool) - 151 - 135 + 63 + 102 - 427 - 134 + 70 + 102 @@ -10299,12 +10358,12 @@ setEnabled(bool) - 151 - 135 + 63 + 102 - 702 - 134 + 77 + 103 @@ -10315,12 +10374,12 @@ setEnabled(bool) - 385 - 194 + 96 + 96 - 654 - 195 + 108 + 96 @@ -10331,12 +10390,12 @@ setEnabled(bool) - 385 - 194 + 96 + 96 - 924 - 195 + 119 + 97 @@ -10347,12 +10406,12 @@ setEnabled(bool) - 564 - 194 + 96 + 95 - 772 - 195 + 108 + 95 @@ -10363,12 +10422,12 @@ setEnabled(bool) - 564 - 194 + 96 + 95 - 980 - 195 + 119 + 96 @@ -10411,12 +10470,12 @@ setEnabled(bool) - 112 - 160 + 87 + 107 - 219 - 159 + 99 + 107 @@ -10427,12 +10486,12 @@ setEnabled(bool) - 365 - 157 + 95 + 97 - 607 - 155 + 108 + 97 @@ -10443,12 +10502,12 @@ setEnabled(bool) - 365 - 157 + 95 + 97 - 846 - 155 + 119 + 98 @@ -10459,12 +10518,12 @@ setEnabled(bool) - 512 - 161 + 96 + 96 - 714 - 160 + 108 + 96 @@ -10475,12 +10534,12 @@ setEnabled(bool) - 512 - 161 + 96 + 96 - 915 - 160 + 119 + 97 @@ -10491,12 +10550,12 @@ setEnabled(bool) - 940 - 498 + 700 + 192 - 241 - 535 + 265 + 229 @@ -10507,12 +10566,12 @@ setEnabled(bool) - 940 - 498 + 700 + 192 - 241 - 664 + 265 + 358 @@ -10523,12 +10582,12 @@ setEnabled(bool) - 940 - 498 + 700 + 192 - 778 - 537 + 604 + 231 @@ -10539,12 +10598,12 @@ setEnabled(bool) - 112 - 160 + 87 + 107 - 326 - 159 + 110 + 108 @@ -10555,12 +10614,12 @@ setEnabled(bool) - 647 - 572 + 330 + 168 - 899 - 572 + 423 + 168 @@ -10619,12 +10678,12 @@ setEnabled(bool) - 139 - 135 + 63 + 101 - 226 - 134 + 73 + 101 @@ -10635,12 +10694,12 @@ setEnabled(bool) - 139 - 135 + 63 + 101 - 419 - 134 + 82 + 102 @@ -10651,12 +10710,12 @@ setVisible(bool) - 121 - 396 + 63 + 109 121 - 492 + 112 @@ -10683,12 +10742,12 @@ setVisible(bool) - 79 - 483 + 101 + 559 - 71 - 556 + 92 + 730 @@ -10715,12 +10774,12 @@ setVisible(bool) - 138 - 458 + 151 + 503 - 162 - 488 + 175 + 727 @@ -10731,12 +10790,12 @@ setVisible(bool) - 106 - 521 + 52 + 122 - 129 - 535 + 121 + 117 @@ -10747,12 +10806,12 @@ setVisible(bool) - 105 - 398 + 119 + 456 - 136 - 421 + 149 + 727 @@ -10763,12 +10822,44 @@ setVisible(bool) - 81 - 489 + 55 + 114 + + + 113 + 116 + + + + + checkBox_set_taxa_func_split_func + clicked(bool) + lineEdit_set_taxa_func_split_func_sep + setEnabled(bool) + + + 857 + 146 + + + 953 + 145 + + + + + checkBox_set_taxa_func_split_func + clicked(bool) + checkBox_set_taxa_func_split_func_share_intensity + setEnabled(bool) + + + 832 + 146 - 100 - 523 + 1044 + 141 diff --git a/metax/gui/metax_gui/ui_main_window.py b/metax/gui/metax_gui/ui_main_window.py index 99c7cef..ba6a8a6 100644 --- a/metax/gui/metax_gui/ui_main_window.py +++ b/metax/gui/metax_gui/ui_main_window.py @@ -147,7 +147,7 @@ def setupUi(self, metaX_main): self.toolBox_2.setMaximumSize(QtCore.QSize(1677, 16777215)) self.toolBox_2.setObjectName("toolBox_2") self.page_2 = QtWidgets.QWidget() - self.page_2.setGeometry(QtCore.QRect(0, 0, 391, 80)) + self.page_2.setGeometry(QtCore.QRect(0, 0, 528, 569)) self.page_2.setObjectName("page_2") self.gridLayout_27 = QtWidgets.QGridLayout(self.page_2) self.gridLayout_27.setObjectName("gridLayout_27") @@ -274,103 +274,6 @@ def setupUi(self, metaX_main): self.tab_set_taxa_func.setObjectName("tab_set_taxa_func") self.gridLayout_25 = QtWidgets.QGridLayout(self.tab_set_taxa_func) self.gridLayout_25.setObjectName("gridLayout_25") - self.gridLayout_17 = QtWidgets.QGridLayout() - self.gridLayout_17.setObjectName("gridLayout_17") - self.label_128 = QtWidgets.QLabel(self.tab_set_taxa_func) - self.label_128.setObjectName("label_128") - self.gridLayout_17.addWidget(self.label_128, 1, 2, 1, 2) - self.comboBox_function_to_stast = QtWidgets.QComboBox(self.tab_set_taxa_func) - sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Preferred, QtWidgets.QSizePolicy.Fixed) - sizePolicy.setHorizontalStretch(0) - sizePolicy.setVerticalStretch(0) - sizePolicy.setHeightForWidth(self.comboBox_function_to_stast.sizePolicy().hasHeightForWidth()) - self.comboBox_function_to_stast.setSizePolicy(sizePolicy) - self.comboBox_function_to_stast.setLayoutDirection(QtCore.Qt.LeftToRight) - self.comboBox_function_to_stast.setObjectName("comboBox_function_to_stast") - self.gridLayout_17.addWidget(self.comboBox_function_to_stast, 0, 1, 1, 1) - self.horizontalLayout = QtWidgets.QHBoxLayout() - self.horizontalLayout.setObjectName("horizontalLayout") - self.label_127 = QtWidgets.QLabel(self.tab_set_taxa_func) - self.label_127.setAlignment(QtCore.Qt.AlignCenter) - self.label_127.setObjectName("label_127") - self.horizontalLayout.addWidget(self.label_127) - self.spinBox_peptide_num_threshold_taxa = QtWidgets.QSpinBox(self.tab_set_taxa_func) - self.spinBox_peptide_num_threshold_taxa.setMinimum(1) - self.spinBox_peptide_num_threshold_taxa.setMaximum(999) - self.spinBox_peptide_num_threshold_taxa.setObjectName("spinBox_peptide_num_threshold_taxa") - self.horizontalLayout.addWidget(self.spinBox_peptide_num_threshold_taxa) - self.label_126 = QtWidgets.QLabel(self.tab_set_taxa_func) - self.label_126.setAlignment(QtCore.Qt.AlignCenter) - self.label_126.setObjectName("label_126") - self.horizontalLayout.addWidget(self.label_126) - self.spinBox_peptide_num_threshold_func = QtWidgets.QSpinBox(self.tab_set_taxa_func) - self.spinBox_peptide_num_threshold_func.setMinimum(1) - self.spinBox_peptide_num_threshold_func.setMaximum(999) - self.spinBox_peptide_num_threshold_func.setObjectName("spinBox_peptide_num_threshold_func") - self.horizontalLayout.addWidget(self.spinBox_peptide_num_threshold_func) - self.label_123 = QtWidgets.QLabel(self.tab_set_taxa_func) - self.label_123.setAlignment(QtCore.Qt.AlignCenter) - self.label_123.setObjectName("label_123") - self.horizontalLayout.addWidget(self.label_123) - self.spinBox_peptide_num_threshold_taxa_func = QtWidgets.QSpinBox(self.tab_set_taxa_func) - self.spinBox_peptide_num_threshold_taxa_func.setMinimum(1) - self.spinBox_peptide_num_threshold_taxa_func.setMaximum(999) - self.spinBox_peptide_num_threshold_taxa_func.setObjectName("spinBox_peptide_num_threshold_taxa_func") - self.horizontalLayout.addWidget(self.spinBox_peptide_num_threshold_taxa_func) - self.gridLayout_17.addLayout(self.horizontalLayout, 1, 4, 1, 1) - self.label_44 = QtWidgets.QLabel(self.tab_set_taxa_func) - sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Fixed, QtWidgets.QSizePolicy.Preferred) - sizePolicy.setHorizontalStretch(0) - sizePolicy.setVerticalStretch(0) - sizePolicy.setHeightForWidth(self.label_44.sizePolicy().hasHeightForWidth()) - self.label_44.setSizePolicy(sizePolicy) - self.label_44.setObjectName("label_44") - self.gridLayout_17.addWidget(self.label_44, 0, 2, 1, 1) - self.doubleSpinBox_func_threshold = QtWidgets.QDoubleSpinBox(self.tab_set_taxa_func) - sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Preferred, QtWidgets.QSizePolicy.Fixed) - sizePolicy.setHorizontalStretch(0) - sizePolicy.setVerticalStretch(0) - sizePolicy.setHeightForWidth(self.doubleSpinBox_func_threshold.sizePolicy().hasHeightForWidth()) - self.doubleSpinBox_func_threshold.setSizePolicy(sizePolicy) - self.doubleSpinBox_func_threshold.setDecimals(3) - self.doubleSpinBox_func_threshold.setMaximum(1.0) - self.doubleSpinBox_func_threshold.setSingleStep(0.05) - self.doubleSpinBox_func_threshold.setProperty("value", 1.0) - self.doubleSpinBox_func_threshold.setObjectName("doubleSpinBox_func_threshold") - self.gridLayout_17.addWidget(self.doubleSpinBox_func_threshold, 0, 4, 1, 1) - self.comboBox_taxa_level_to_stast = QtWidgets.QComboBox(self.tab_set_taxa_func) - self.comboBox_taxa_level_to_stast.setLayoutDirection(QtCore.Qt.LeftToRight) - self.comboBox_taxa_level_to_stast.setObjectName("comboBox_taxa_level_to_stast") - self.comboBox_taxa_level_to_stast.addItem("") - self.comboBox_taxa_level_to_stast.addItem("") - self.comboBox_taxa_level_to_stast.addItem("") - self.comboBox_taxa_level_to_stast.addItem("") - self.comboBox_taxa_level_to_stast.addItem("") - self.comboBox_taxa_level_to_stast.addItem("") - self.comboBox_taxa_level_to_stast.addItem("") - self.comboBox_taxa_level_to_stast.addItem("") - self.comboBox_taxa_level_to_stast.addItem("") - self.gridLayout_17.addWidget(self.comboBox_taxa_level_to_stast, 1, 1, 1, 1) - self.label_27 = QtWidgets.QLabel(self.tab_set_taxa_func) - sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Fixed, QtWidgets.QSizePolicy.Preferred) - sizePolicy.setHorizontalStretch(0) - sizePolicy.setVerticalStretch(0) - sizePolicy.setHeightForWidth(self.label_27.sizePolicy().hasHeightForWidth()) - self.label_27.setSizePolicy(sizePolicy) - self.label_27.setObjectName("label_27") - self.gridLayout_17.addWidget(self.label_27, 0, 0, 1, 1) - self.pushButton_func_threshold_help = QtWidgets.QPushButton(self.tab_set_taxa_func) - sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Fixed, QtWidgets.QSizePolicy.Fixed) - sizePolicy.setHorizontalStretch(0) - sizePolicy.setVerticalStretch(0) - sizePolicy.setHeightForWidth(self.pushButton_func_threshold_help.sizePolicy().hasHeightForWidth()) - self.pushButton_func_threshold_help.setSizePolicy(sizePolicy) - self.pushButton_func_threshold_help.setObjectName("pushButton_func_threshold_help") - self.gridLayout_17.addWidget(self.pushButton_func_threshold_help, 0, 3, 1, 1) - self.label_28 = QtWidgets.QLabel(self.tab_set_taxa_func) - self.label_28.setObjectName("label_28") - self.gridLayout_17.addWidget(self.label_28, 1, 0, 1, 1) - self.gridLayout_25.addLayout(self.gridLayout_17, 1, 0, 1, 1) self.label_134 = QtWidgets.QLabel(self.tab_set_taxa_func) sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Preferred, QtWidgets.QSizePolicy.Maximum) sizePolicy.setHorizontalStretch(0) @@ -431,10 +334,6 @@ def setupUi(self, metaX_main): self.gridLayout_25.addWidget(self.label_39, 6, 0, 1, 1) self.gridLayout_37 = QtWidgets.QGridLayout() self.gridLayout_37.setObjectName("gridLayout_37") - self.checkBox_infrence_protein_by_sample = QtWidgets.QCheckBox(self.tab_set_taxa_func) - self.checkBox_infrence_protein_by_sample.setEnabled(False) - self.checkBox_infrence_protein_by_sample.setObjectName("checkBox_infrence_protein_by_sample") - self.gridLayout_37.addWidget(self.checkBox_infrence_protein_by_sample, 1, 1, 1, 1) self.comboBox_method_of_protein_inference = QtWidgets.QComboBox(self.tab_set_taxa_func) self.comboBox_method_of_protein_inference.setEnabled(False) self.comboBox_method_of_protein_inference.setObjectName("comboBox_method_of_protein_inference") @@ -442,6 +341,10 @@ def setupUi(self, metaX_main): self.comboBox_method_of_protein_inference.addItem("") self.comboBox_method_of_protein_inference.addItem("") self.gridLayout_37.addWidget(self.comboBox_method_of_protein_inference, 0, 2, 1, 1) + self.checkBox_infrence_protein_by_sample = QtWidgets.QCheckBox(self.tab_set_taxa_func) + self.checkBox_infrence_protein_by_sample.setEnabled(False) + self.checkBox_infrence_protein_by_sample.setObjectName("checkBox_infrence_protein_by_sample") + self.gridLayout_37.addWidget(self.checkBox_infrence_protein_by_sample, 1, 1, 1, 1) self.horizontalLayout_2 = QtWidgets.QHBoxLayout() self.horizontalLayout_2.setObjectName("horizontalLayout_2") self.label_136 = QtWidgets.QLabel(self.tab_set_taxa_func) @@ -660,6 +563,127 @@ def setupUi(self, metaX_main): self.horizontalLayout_27.addWidget(self.comboBox_outlier_handling_group_or_sample) self.gridLayout_15.addLayout(self.horizontalLayout_27, 3, 2, 1, 1) self.gridLayout_25.addLayout(self.gridLayout_15, 9, 0, 1, 1) + self.gridLayout_17 = QtWidgets.QGridLayout() + self.gridLayout_17.setObjectName("gridLayout_17") + self.label_128 = QtWidgets.QLabel(self.tab_set_taxa_func) + self.label_128.setObjectName("label_128") + self.gridLayout_17.addWidget(self.label_128, 1, 2, 1, 1) + self.label_28 = QtWidgets.QLabel(self.tab_set_taxa_func) + self.label_28.setObjectName("label_28") + self.gridLayout_17.addWidget(self.label_28, 1, 0, 1, 1) + self.label_27 = QtWidgets.QLabel(self.tab_set_taxa_func) + sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Fixed, QtWidgets.QSizePolicy.Preferred) + sizePolicy.setHorizontalStretch(0) + sizePolicy.setVerticalStretch(0) + sizePolicy.setHeightForWidth(self.label_27.sizePolicy().hasHeightForWidth()) + self.label_27.setSizePolicy(sizePolicy) + self.label_27.setObjectName("label_27") + self.gridLayout_17.addWidget(self.label_27, 0, 0, 1, 1) + self.horizontalLayout_95 = QtWidgets.QHBoxLayout() + self.horizontalLayout_95.setObjectName("horizontalLayout_95") + self.pushButton_func_threshold_help = QtWidgets.QPushButton(self.tab_set_taxa_func) + sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Fixed, QtWidgets.QSizePolicy.Fixed) + sizePolicy.setHorizontalStretch(0) + sizePolicy.setVerticalStretch(0) + sizePolicy.setHeightForWidth(self.pushButton_func_threshold_help.sizePolicy().hasHeightForWidth()) + self.pushButton_func_threshold_help.setSizePolicy(sizePolicy) + self.pushButton_func_threshold_help.setObjectName("pushButton_func_threshold_help") + self.horizontalLayout_95.addWidget(self.pushButton_func_threshold_help) + self.doubleSpinBox_func_threshold = QtWidgets.QDoubleSpinBox(self.tab_set_taxa_func) + sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Preferred, QtWidgets.QSizePolicy.Fixed) + sizePolicy.setHorizontalStretch(0) + sizePolicy.setVerticalStretch(0) + sizePolicy.setHeightForWidth(self.doubleSpinBox_func_threshold.sizePolicy().hasHeightForWidth()) + self.doubleSpinBox_func_threshold.setSizePolicy(sizePolicy) + self.doubleSpinBox_func_threshold.setDecimals(3) + self.doubleSpinBox_func_threshold.setMaximum(1.0) + self.doubleSpinBox_func_threshold.setSingleStep(0.05) + self.doubleSpinBox_func_threshold.setProperty("value", 1.0) + self.doubleSpinBox_func_threshold.setObjectName("doubleSpinBox_func_threshold") + self.horizontalLayout_95.addWidget(self.doubleSpinBox_func_threshold) + self.gridLayout_17.addLayout(self.horizontalLayout_95, 0, 3, 1, 1) + self.comboBox_taxa_level_to_stast = QtWidgets.QComboBox(self.tab_set_taxa_func) + self.comboBox_taxa_level_to_stast.setLayoutDirection(QtCore.Qt.LeftToRight) + self.comboBox_taxa_level_to_stast.setObjectName("comboBox_taxa_level_to_stast") + self.comboBox_taxa_level_to_stast.addItem("") + self.comboBox_taxa_level_to_stast.addItem("") + self.comboBox_taxa_level_to_stast.addItem("") + self.comboBox_taxa_level_to_stast.addItem("") + self.comboBox_taxa_level_to_stast.addItem("") + self.comboBox_taxa_level_to_stast.addItem("") + self.comboBox_taxa_level_to_stast.addItem("") + self.comboBox_taxa_level_to_stast.addItem("") + self.comboBox_taxa_level_to_stast.addItem("") + self.gridLayout_17.addWidget(self.comboBox_taxa_level_to_stast, 1, 1, 1, 1) + self.comboBox_function_to_stast = QtWidgets.QComboBox(self.tab_set_taxa_func) + sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Preferred, QtWidgets.QSizePolicy.Fixed) + sizePolicy.setHorizontalStretch(0) + sizePolicy.setVerticalStretch(0) + sizePolicy.setHeightForWidth(self.comboBox_function_to_stast.sizePolicy().hasHeightForWidth()) + self.comboBox_function_to_stast.setSizePolicy(sizePolicy) + self.comboBox_function_to_stast.setLayoutDirection(QtCore.Qt.LeftToRight) + self.comboBox_function_to_stast.setObjectName("comboBox_function_to_stast") + self.gridLayout_17.addWidget(self.comboBox_function_to_stast, 0, 1, 1, 1) + self.label_44 = QtWidgets.QLabel(self.tab_set_taxa_func) + sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Fixed, QtWidgets.QSizePolicy.Preferred) + sizePolicy.setHorizontalStretch(0) + sizePolicy.setVerticalStretch(0) + sizePolicy.setHeightForWidth(self.label_44.sizePolicy().hasHeightForWidth()) + self.label_44.setSizePolicy(sizePolicy) + self.label_44.setObjectName("label_44") + self.gridLayout_17.addWidget(self.label_44, 0, 2, 1, 1) + self.horizontalLayout = QtWidgets.QHBoxLayout() + self.horizontalLayout.setObjectName("horizontalLayout") + self.label_127 = QtWidgets.QLabel(self.tab_set_taxa_func) + self.label_127.setAlignment(QtCore.Qt.AlignCenter) + self.label_127.setObjectName("label_127") + self.horizontalLayout.addWidget(self.label_127) + self.spinBox_peptide_num_threshold_taxa = QtWidgets.QSpinBox(self.tab_set_taxa_func) + self.spinBox_peptide_num_threshold_taxa.setMinimum(1) + self.spinBox_peptide_num_threshold_taxa.setMaximum(999) + self.spinBox_peptide_num_threshold_taxa.setObjectName("spinBox_peptide_num_threshold_taxa") + self.horizontalLayout.addWidget(self.spinBox_peptide_num_threshold_taxa) + self.label_126 = QtWidgets.QLabel(self.tab_set_taxa_func) + self.label_126.setAlignment(QtCore.Qt.AlignCenter) + self.label_126.setObjectName("label_126") + self.horizontalLayout.addWidget(self.label_126) + self.spinBox_peptide_num_threshold_func = QtWidgets.QSpinBox(self.tab_set_taxa_func) + self.spinBox_peptide_num_threshold_func.setMinimum(1) + self.spinBox_peptide_num_threshold_func.setMaximum(999) + self.spinBox_peptide_num_threshold_func.setObjectName("spinBox_peptide_num_threshold_func") + self.horizontalLayout.addWidget(self.spinBox_peptide_num_threshold_func) + self.label_123 = QtWidgets.QLabel(self.tab_set_taxa_func) + self.label_123.setAlignment(QtCore.Qt.AlignCenter) + self.label_123.setObjectName("label_123") + self.horizontalLayout.addWidget(self.label_123) + self.spinBox_peptide_num_threshold_taxa_func = QtWidgets.QSpinBox(self.tab_set_taxa_func) + self.spinBox_peptide_num_threshold_taxa_func.setMinimum(1) + self.spinBox_peptide_num_threshold_taxa_func.setMaximum(999) + self.spinBox_peptide_num_threshold_taxa_func.setObjectName("spinBox_peptide_num_threshold_taxa_func") + self.horizontalLayout.addWidget(self.spinBox_peptide_num_threshold_taxa_func) + self.gridLayout_17.addLayout(self.horizontalLayout, 1, 3, 1, 2) + self.horizontalLayout_96 = QtWidgets.QHBoxLayout() + self.horizontalLayout_96.setObjectName("horizontalLayout_96") + self.checkBox_set_taxa_func_split_func = QtWidgets.QCheckBox(self.tab_set_taxa_func) + self.checkBox_set_taxa_func_split_func.setObjectName("checkBox_set_taxa_func_split_func") + self.horizontalLayout_96.addWidget(self.checkBox_set_taxa_func_split_func) + self.lineEdit_set_taxa_func_split_func_sep = QtWidgets.QLineEdit(self.tab_set_taxa_func) + self.lineEdit_set_taxa_func_split_func_sep.setEnabled(False) + sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Minimum, QtWidgets.QSizePolicy.Fixed) + sizePolicy.setHorizontalStretch(0) + sizePolicy.setVerticalStretch(0) + sizePolicy.setHeightForWidth(self.lineEdit_set_taxa_func_split_func_sep.sizePolicy().hasHeightForWidth()) + self.lineEdit_set_taxa_func_split_func_sep.setSizePolicy(sizePolicy) + self.lineEdit_set_taxa_func_split_func_sep.setMaximumSize(QtCore.QSize(50, 16777215)) + self.lineEdit_set_taxa_func_split_func_sep.setAlignment(QtCore.Qt.AlignCenter) + self.lineEdit_set_taxa_func_split_func_sep.setObjectName("lineEdit_set_taxa_func_split_func_sep") + self.horizontalLayout_96.addWidget(self.lineEdit_set_taxa_func_split_func_sep) + self.checkBox_set_taxa_func_split_func_share_intensity = QtWidgets.QCheckBox(self.tab_set_taxa_func) + self.checkBox_set_taxa_func_split_func_share_intensity.setEnabled(False) + self.checkBox_set_taxa_func_split_func_share_intensity.setObjectName("checkBox_set_taxa_func_split_func_share_intensity") + self.horizontalLayout_96.addWidget(self.checkBox_set_taxa_func_split_func_share_intensity) + self.gridLayout_17.addLayout(self.horizontalLayout_96, 0, 4, 1, 1) + self.gridLayout_25.addLayout(self.gridLayout_17, 1, 0, 1, 1) self.tabWidget_TaxaFuncAnalyzer.addTab(self.tab_set_taxa_func, "") self.tab_basic_stast = QtWidgets.QWidget() self.tab_basic_stast.setObjectName("tab_basic_stast") @@ -1919,7 +1943,7 @@ def setupUi(self, metaX_main): self.scrollArea_cross_heatmap_settings.setWidgetResizable(True) self.scrollArea_cross_heatmap_settings.setObjectName("scrollArea_cross_heatmap_settings") self.scrollAreaWidgetContents_3 = QtWidgets.QWidget() - self.scrollAreaWidgetContents_3.setGeometry(QtCore.QRect(0, 0, 929, 126)) + self.scrollAreaWidgetContents_3.setGeometry(QtCore.QRect(0, 0, 1020, 126)) self.scrollAreaWidgetContents_3.setObjectName("scrollAreaWidgetContents_3") self.gridLayout_38 = QtWidgets.QGridLayout(self.scrollAreaWidgetContents_3) self.gridLayout_38.setObjectName("gridLayout_38") @@ -2844,7 +2868,7 @@ def setupUi(self, metaX_main): self.scrollArea_3.setWidgetResizable(True) self.scrollArea_3.setObjectName("scrollArea_3") self.scrollAreaWidgetContents_4 = QtWidgets.QWidget() - self.scrollAreaWidgetContents_4.setGeometry(QtCore.QRect(0, 0, 535, 94)) + self.scrollAreaWidgetContents_4.setGeometry(QtCore.QRect(0, 0, 996, 140)) self.scrollAreaWidgetContents_4.setObjectName("scrollAreaWidgetContents_4") self.gridLayout_68 = QtWidgets.QGridLayout(self.scrollAreaWidgetContents_4) self.gridLayout_68.setObjectName("gridLayout_68") @@ -3145,7 +3169,7 @@ def setupUi(self, metaX_main): self.scrollArea_4.setWidgetResizable(True) self.scrollArea_4.setObjectName("scrollArea_4") self.scrollAreaWidgetContents_5 = QtWidgets.QWidget() - self.scrollAreaWidgetContents_5.setGeometry(QtCore.QRect(0, 0, 493, 128)) + self.scrollAreaWidgetContents_5.setGeometry(QtCore.QRect(0, 0, 1016, 179)) self.scrollAreaWidgetContents_5.setObjectName("scrollAreaWidgetContents_5") self.gridLayout_49 = QtWidgets.QGridLayout(self.scrollAreaWidgetContents_5) self.gridLayout_49.setObjectName("gridLayout_49") @@ -5336,7 +5360,7 @@ def setupUi(self, metaX_main): self.retranslateUi(metaX_main) self.stackedWidget.setCurrentIndex(0) - self.tabWidget_TaxaFuncAnalyzer.setCurrentIndex(6) + self.tabWidget_TaxaFuncAnalyzer.setCurrentIndex(2) self.toolBox_2.setCurrentIndex(0) self.tabWidget_4.setCurrentIndex(1) self.tabWidget_3.setCurrentIndex(3) @@ -5380,6 +5404,8 @@ def setupUi(self, metaX_main): self.checkBox_5.toggled['bool'].connect(self.groupBox_expression_trends_plot_settings.setVisible) # type: ignore self.checkBox_6.toggled['bool'].connect(self.groupBox_taxa_func_link_plot_settings.setVisible) # type: ignore self.checkBox_7.toggled['bool'].connect(self.groupBox_taxa_func_link_net_plot_settings.setVisible) # type: ignore + self.checkBox_set_taxa_func_split_func.clicked['bool'].connect(self.lineEdit_set_taxa_func_split_func_sep.setEnabled) # type: ignore + self.checkBox_set_taxa_func_split_func.clicked['bool'].connect(self.checkBox_set_taxa_func_split_func_share_intensity.setEnabled) # type: ignore QtCore.QMetaObject.connectSlotsByName(metaX_main) metaX_main.setTabOrder(self.comboBox_taxa_level_to_stast, self.toolButton_meta_table_help) metaX_main.setTabOrder(self.toolButton_meta_table_help, self.comboBox_function_to_stast) @@ -5422,32 +5448,14 @@ def retranslateUi(self, metaX_main): self.pushButton_overview_run_filter.setText(_translate("metaX_main", "Run Filter")) self.toolBox_2.setItemText(self.toolBox_2.indexOf(self.page), _translate("metaX_main", "● Filter Samples")) self.tabWidget_TaxaFuncAnalyzer.setTabText(self.tabWidget_TaxaFuncAnalyzer.indexOf(self.tab_overview), _translate("metaX_main", "Data Overview")) - self.label_128.setText(_translate("metaX_main", "Peptide Number Threshold")) - self.label_127.setText(_translate("metaX_main", "Taxa")) - self.label_126.setText(_translate("metaX_main", "Func")) - self.label_123.setText(_translate("metaX_main", "Taxa-Func")) - self.label_44.setText(_translate("metaX_main", "Function Filter Threshold")) - self.comboBox_taxa_level_to_stast.setCurrentText(_translate("metaX_main", "Genome")) - self.comboBox_taxa_level_to_stast.setItemText(0, _translate("metaX_main", "Genome")) - self.comboBox_taxa_level_to_stast.setItemText(1, _translate("metaX_main", "Species")) - self.comboBox_taxa_level_to_stast.setItemText(2, _translate("metaX_main", "Genus")) - self.comboBox_taxa_level_to_stast.setItemText(3, _translate("metaX_main", "Family")) - self.comboBox_taxa_level_to_stast.setItemText(4, _translate("metaX_main", "Order")) - self.comboBox_taxa_level_to_stast.setItemText(5, _translate("metaX_main", "Class")) - self.comboBox_taxa_level_to_stast.setItemText(6, _translate("metaX_main", "Phylum")) - self.comboBox_taxa_level_to_stast.setItemText(7, _translate("metaX_main", "Domain")) - self.comboBox_taxa_level_to_stast.setItemText(8, _translate("metaX_main", "Life")) - self.label_27.setText(_translate("metaX_main", "Function")) - self.pushButton_func_threshold_help.setText(_translate("metaX_main", "?")) - self.label_28.setText(_translate("metaX_main", "Taxa Level")) self.label_134.setText(_translate("metaX_main", "Sum Proteins Intensity")) self.pushButton_set_multi_table.setText(_translate("metaX_main", "GO")) self.label_105.setText(_translate("metaX_main", "Function and Taxa")) self.label_39.setText(_translate("metaX_main", "Data Preprocessing")) - self.checkBox_infrence_protein_by_sample.setText(_translate("metaX_main", "Inference by each Sample")) self.comboBox_method_of_protein_inference.setItemText(0, _translate("metaX_main", "razor")) self.comboBox_method_of_protein_inference.setItemText(1, _translate("metaX_main", "anti-razor")) self.comboBox_method_of_protein_inference.setItemText(2, _translate("metaX_main", "rank")) + self.checkBox_infrence_protein_by_sample.setText(_translate("metaX_main", "Inference by each Sample")) self.label_136.setText(_translate("metaX_main", "Protein Ranking Method")) self.comboBox_protein_ranking_method.setItemText(0, _translate("metaX_main", "unique_counts")) self.comboBox_protein_ranking_method.setItemText(1, _translate("metaX_main", "all_counts")) @@ -5512,6 +5520,30 @@ def retranslateUi(self, metaX_main): self.radioButton_data_preprocessing_after_sum.setText(_translate("metaX_main", "After Summing Peptides")) self.label_45.setText(_translate("metaX_main", "Drag to change the processing order")) self.label_102.setText(_translate("metaX_main", "Outliers Handling by")) + self.label_128.setText(_translate("metaX_main", "Peptide Number Threshold")) + self.label_28.setText(_translate("metaX_main", "Taxa Level")) + self.label_27.setText(_translate("metaX_main", "Function")) + self.pushButton_func_threshold_help.setText(_translate("metaX_main", "?")) + self.comboBox_taxa_level_to_stast.setCurrentText(_translate("metaX_main", "Genome")) + self.comboBox_taxa_level_to_stast.setItemText(0, _translate("metaX_main", "Genome")) + self.comboBox_taxa_level_to_stast.setItemText(1, _translate("metaX_main", "Species")) + self.comboBox_taxa_level_to_stast.setItemText(2, _translate("metaX_main", "Genus")) + self.comboBox_taxa_level_to_stast.setItemText(3, _translate("metaX_main", "Family")) + self.comboBox_taxa_level_to_stast.setItemText(4, _translate("metaX_main", "Order")) + self.comboBox_taxa_level_to_stast.setItemText(5, _translate("metaX_main", "Class")) + self.comboBox_taxa_level_to_stast.setItemText(6, _translate("metaX_main", "Phylum")) + self.comboBox_taxa_level_to_stast.setItemText(7, _translate("metaX_main", "Domain")) + self.comboBox_taxa_level_to_stast.setItemText(8, _translate("metaX_main", "Life")) + self.label_44.setText(_translate("metaX_main", "Function Filter Threshold")) + self.label_127.setText(_translate("metaX_main", "Taxa")) + self.label_126.setText(_translate("metaX_main", "Func")) + self.label_123.setText(_translate("metaX_main", "Taxa-Func")) + self.checkBox_set_taxa_func_split_func.setToolTip(_translate("metaX_main", "Split items that contain multiple functions")) + self.checkBox_set_taxa_func_split_func.setText(_translate("metaX_main", "Split Functions By")) + self.lineEdit_set_taxa_func_split_func_sep.setToolTip(_translate("metaX_main", "Separator between multiple functions")) + self.lineEdit_set_taxa_func_split_func_sep.setText(_translate("metaX_main", ";")) + self.checkBox_set_taxa_func_split_func_share_intensity.setToolTip(_translate("metaX_main", "YES: Each function shares the average Intensity after splitting. NO: Every function gives the original Intensity value after splitting.")) + self.checkBox_set_taxa_func_split_func_share_intensity.setText(_translate("metaX_main", "Share Intensty")) self.tabWidget_TaxaFuncAnalyzer.setTabText(self.tabWidget_TaxaFuncAnalyzer.indexOf(self.tab_set_taxa_func), _translate("metaX_main", "Set TaxaFunc")) self.checkBox_show_basic_plot_settings.setText(_translate("metaX_main", "Show Plotting Parameter")) self.groupBox_basic_plot.setTitle(_translate("metaX_main", "Plotting Parameter")) diff --git a/metax/taxafunc_analyzer/analyzer.py b/metax/taxafunc_analyzer/analyzer.py index 4d4f616..452cffc 100644 --- a/metax/taxafunc_analyzer/analyzer.py +++ b/metax/taxafunc_analyzer/analyzer.py @@ -13,13 +13,21 @@ import pandas as pd from typing import Optional, Dict, List, Union +from tqdm import tqdm # import AnalyzerUtils -from .analyzer_utils.data_preprocessing import DataPreprocessing -from .analyzer_utils.sum_protein_intensity import SumProteinIntensity -from .analyzer_utils.basic_stats import BasicStats -from .analyzer_utils.cross_test import CrossTest -from .analyzer_utils.get_matrix import GetMatrix +if __name__ == '__main__': + from analyzer_utils.data_preprocessing import DataPreprocessing + from analyzer_utils.sum_protein_intensity import SumProteinIntensity + from analyzer_utils.basic_stats import BasicStats + from analyzer_utils.cross_test import CrossTest + from analyzer_utils.get_matrix import GetMatrix +else: + from .analyzer_utils.data_preprocessing import DataPreprocessing + from .analyzer_utils.sum_protein_intensity import SumProteinIntensity + from .analyzer_utils.basic_stats import BasicStats + from .analyzer_utils.cross_test import CrossTest + from .analyzer_utils.get_matrix import GetMatrix import warnings @@ -518,6 +526,57 @@ def set_any_df_table(self, data_preprocess_params: dict = {'normalize_method': N self.func_taxa_linked_dict= {self.func_name: [('d__Bacteria', 1)]} print("Custom df is set!\nWaiting for further analysis...") + + + def split_func(self, taxa_func_df, split_func_params: dict = {'split_by': ',', 'share_intensity': False}): + """ + Splits the function column in the given taxa_func_df DataFrame based on the specified parameters. + Parameters: + - taxa_func_df (DataFrame): The DataFrame containing taxa and function data. + - split_func_params (dict): A dictionary of parameters for the split function. + - split_by (str): The delimiter used to split the function column (default: ','). + - share_intensity (bool): Whether to share the intensity values among the split functions (default: False). + Returns: + - new_data (DataFrame): The new DataFrame with the split function column. + """ + + split_by = split_func_params['split_by'] + share_intensity = split_func_params['share_intensity'] + df = taxa_func_df.copy() + + print(f'Start splitting function by [{split_by}] for {df.index.name}, share_intensity={share_intensity}, it may take a while...') + + # multi index + df = df.reset_index() + func_col = self.func_name + sample_list = self.sample_list + taxon_col = 'Taxon' + + result_rows = [] + + for _, row in tqdm(df.iterrows(), total=len(df), desc="Splitting functions"): + split_funcs_list = row[func_col].split(split_by) + num_splits = len(split_funcs_list) + + for new_func in split_funcs_list: + split_row = row[sample_list] / num_splits if share_intensity else row[sample_list] + split_row[func_col] = new_func + split_row[taxon_col] = row[taxon_col] + + # Use the peptide_num of the original row + split_row['peptide_num'] = row['peptide_num'] + + result_rows.append((row[taxon_col], new_func, split_row)) + + # create a new multi index + new_index = pd.MultiIndex.from_tuples([(tax, func) for tax, func, _ in result_rows], names=[taxon_col, func_col]) + new_data = pd.DataFrame([split_row for _, _, split_row in result_rows], index=new_index) + # drop the taxon and func columns + new_data.drop(columns=[taxon_col, func_col], inplace=True) + # move the peptide_num to the first column if it exists + new_data = new_data[['peptide_num'] + [col for col in new_data.columns if col != 'peptide_num']] + + return new_data def set_multi_tables(self, level: str = 's', func_threshold:float = 1.00, @@ -534,7 +593,8 @@ def set_multi_tables(self, level: str = 's', func_threshold:float = 1.00, 'rank_method': 'unique_counts', 'greedy_method': 'heap', }, - keep_unknow_func: bool = False + keep_unknow_func: bool = False, + split_func: bool = False, split_func_params: dict = {'split_by': '|', 'share_intensity': False} ): """ Example Usage: @@ -618,9 +678,7 @@ def strip_taxa(x, level): # add column 'peptide_num' to df_taxa as 1 df_taxa['peptide_num'] = 1 # move the column 'peptide_num' to the first column - cols = list(df_taxa.columns) - cols = [cols[-1]] + cols[:-1] - df_taxa = df_taxa[cols] + df_taxa = df_taxa[['peptide_num'] + [col for col in df_taxa.columns if col != 'peptide_num']] # groupby 'Taxon' and sum the sample intensity df_taxa = df_taxa.groupby('Taxon').sum(numeric_only=True) @@ -640,24 +698,6 @@ def strip_taxa(x, level): dfc = dfc[filter_conditions] - - print("Starting to set Function table...") - df_func = dfc.copy() - df_func = df_func.groupby(self.func_name).sum(numeric_only=True)[self.sample_list] - if processing_after_sum: - print("\n-----Starting to perform data pre-processing for Function table...-----") - df_func = self.data_preprocess(df=df_func,df_name = 'func', **data_preprocess_params) - - # add column 'peptide_num' to df_func - df_func['peptide_num'] = dfc.groupby(self.func_name).count()[self.peptide_col_name] - # move the column 'peptide_num' to the first column - cols = list(df_func.columns) - cols = [cols[-1]] + cols[:-1] - df_func = df_func[cols] - # filter the df_func by peptide_num_threshold - df_func = df_func[df_func['peptide_num'] >= peptide_num_threshold['func']] - print(f"Function number with prop >= [{func_threshold}], peptide_num >= [{peptide_num_threshold['func']}]: {df_func.shape[0]}") - # create clean peptide table if processing_after_sum: @@ -679,7 +719,6 @@ def strip_taxa(x, level): - if processing_after_sum: print("\n-----Starting to perform data pre-processing for Taxa table...-----") df_taxa = self.data_preprocess(df=df_taxa,df_name = 'taxa', **data_preprocess_params) @@ -688,30 +727,54 @@ def strip_taxa(x, level): # filter the df_taxa by peptide_num_threshold df_taxa = df_taxa[df_taxa['peptide_num'] >= peptide_num_threshold['taxa']] print(f"Taxa number with '{level}' level, peptide_num >= [{peptide_num_threshold['taxa']}]: {df_taxa.shape[0]}") + #-----Taxa Table End----- - - # create taxa-func central table - df_taxa_func = dfc.groupby(['Taxon', self.func_name], as_index=True).sum(numeric_only=True) + # ----- create taxa_func table ----- + df_taxa_func = dfc.copy() + df_taxa_func['peptide_num'] = 1 + df_taxa_func = df_taxa_func.groupby(['Taxon', self.func_name], as_index=True).sum(numeric_only=True) if processing_after_sum: print("\n-----Starting to perform data pre-processing for Taxa-Function table...-----") df_taxa_func = self.data_preprocess(df=df_taxa_func,df_name = 'taxa_func', **data_preprocess_params) # add column 'peptide_num' to df_taxa_func - df_taxa_func['peptide_num'] = dfc.groupby(['Taxon', self.func_name]).count()[self.peptide_col_name] + # df_taxa_func['peptide_num'] = dfc.groupby(['Taxon', self.func_name]).count()[self.peptide_col_name] + if split_func: + df_taxa_func = self.split_func(df_taxa_func, split_func_params) + + # save the df_taxa_func before filter for calculating the func table later + df_taxa_func_before_filter = df_taxa_func.copy() + # filter the df by peptide_num_threshold df_taxa_func = df_taxa_func[df_taxa_func['peptide_num'] >= peptide_num_threshold['taxa_func']] # move the column 'peptide_num' to the first column - cols = list(df_taxa_func.columns) - cols = [cols[-1]] + cols[:-1] - df_taxa_func = df_taxa_func[cols] - + df_taxa_func = df_taxa_func[['peptide_num'] + [col for col in df_taxa_func.columns if col != 'peptide_num']] + # -----taxa_func table End----- + # exchange the multi-index, sort the index df_func_taxa = df_taxa_func.swaplevel().sort_index() print(f"Taxa-Function number with peptide_num >= [{peptide_num_threshold['taxa_func']}]: {df_taxa_func.shape[0]}") + # ----- func_taxa table End ----- + + # ----- create func table ----- + print("Starting to set Function table...") + df_func = df_taxa_func_before_filter.groupby(self.func_name).sum(numeric_only=True) + + if processing_after_sum: + print("\n-----Starting to perform data pre-processing for Function table...-----") + func_pep_num_dict = df_func['peptide_num'].to_dict() + df_func = self.data_preprocess(df=df_func[self.sample_list],df_name = 'func', **data_preprocess_params) + df_func['peptide_num'] = df_func.index.map(func_pep_num_dict) + # move the column 'peptide_num' to the first column + df_func = df_func[['peptide_num'] + [col for col in df_func.columns if col != 'peptide_num']] + # filter the df_func by peptide_num_threshold + df_func = df_func[df_func['peptide_num'] >= peptide_num_threshold['func']] + print(f"Function number with prop >= [{func_threshold}], peptide_num >= [{peptide_num_threshold['func']}]: {df_func.shape[0]}") + # ----- func table End ----- self.taxa_df = df_taxa self.func_df = df_func @@ -808,13 +871,16 @@ def get_df(self, table_name:str = 'taxa'): meta_path = os.path.join(current_path, meta_path) sw = TaxaFuncAnalyzer(df_path, meta_path) - sw.set_func('dbcan_EC') - sw.set_multi_tables(level='m', data_preprocess_params = {'normalize_method': None, 'transform_method': "log10", + sw.set_func('KEGG_Pathway_name') + sw.set_multi_tables(level='s', data_preprocess_params = {'normalize_method': None, 'transform_method': "log10", 'batch_meta': None, 'outlier_detect_method': None, 'outlier_handle_method': None, 'outlier_detect_by_group': None, 'outlier_handle_by_group': None, 'processing_order': None}, - peptide_num_threshold = {'taxa': 3, 'func': 3, 'taxa_func': 3},) + peptide_num_threshold = {'taxa': 1, 'func': 1, 'taxa_func': 1}, + keep_unknow_func=False, sum_protein=False, sum_protein_params = {'method': 'razor', 'by_sample': False, 'rank_method': 'unique_counts', 'greedy_method': 'heap'}, + split_func=True, split_func_params = {'split_by': ';', 'share_intensity': False} + ) sw.check_attributes() \ No newline at end of file diff --git a/metax/utils/version.py b/metax/utils/version.py index 6c5bbab..6ecb2a8 100644 --- a/metax/utils/version.py +++ b/metax/utils/version.py @@ -1,2 +1,2 @@ -__version__ = '1.110.1' +__version__ = '1.111.0' API_version = '2' \ No newline at end of file diff --git a/pyproject.toml b/pyproject.toml index 9bc7681..486194d 100644 --- a/pyproject.toml +++ b/pyproject.toml @@ -4,7 +4,7 @@ build-backend = "setuptools.build_meta" [project] name = "MetaXTools" -version = "1.110.1" +version = "1.111.0" description = "MetaXTools is a novel tool for linking peptide sequences with taxonomic and functional information in Metaproteomics." readme = "README_PyPi.md" license = { text = "NorthOmics" } From 05181c5723a4afb76be82450a8966cbb96b46f68 Mon Sep 17 00:00:00 2001 From: Qing Date: Wed, 21 Aug 2024 00:30:16 -0400 Subject: [PATCH 2/7] - Fix: Fixed the bug of spliting the function items, the redundant items were not sumed. --- Docs/ChangeLog.md | 7 +++++++ metax/taxafunc_analyzer/analyzer.py | 23 +++++++++++------------ metax/utils/version.py | 2 +- pyproject.toml | 2 +- 4 files changed, 20 insertions(+), 14 deletions(-) diff --git a/Docs/ChangeLog.md b/Docs/ChangeLog.md index 14f4e53..b2baffa 100644 --- a/Docs/ChangeLog.md +++ b/Docs/ChangeLog.md @@ -1,3 +1,10 @@ +# Version: 1.111.1 +## Date: 2024-08-21 +### Changes: +- Fix: Fixed the bug of spliting the function items, the redundant items were not sumed. + + + # Version: 1.111.0 ## Date: 2024-08-20 ### Changes: diff --git a/metax/taxafunc_analyzer/analyzer.py b/metax/taxafunc_analyzer/analyzer.py index 452cffc..4c8ddbd 100644 --- a/metax/taxafunc_analyzer/analyzer.py +++ b/metax/taxafunc_analyzer/analyzer.py @@ -187,7 +187,8 @@ def _index_to_nested_dict(df): pep_num = df.loc[(key1, key2), 'peptide_num'] result_dict.setdefault(key1, []).append((key2, pep_num)) return result_dict - + print("Setting taxa_func_linked_dict and func_taxa_linked_dict...") + self.taxa_func_linked_dict = _index_to_nested_dict(self.taxa_func_df) self.func_taxa_linked_dict = _index_to_nested_dict(self.func_taxa_df) @@ -544,7 +545,7 @@ def split_func(self, taxa_func_df, split_func_params: dict = {'split_by': ',', ' share_intensity = split_func_params['share_intensity'] df = taxa_func_df.copy() - print(f'Start splitting function by [{split_by}] for {df.index.name}, share_intensity={share_intensity}, it may take a while...') + print(f'Start splitting function by [ {split_by} ], share_intensity={share_intensity}, it may take a while...') # multi index df = df.reset_index() @@ -566,16 +567,14 @@ def split_func(self, taxa_func_df, split_func_params: dict = {'split_by': ',', ' # Use the peptide_num of the original row split_row['peptide_num'] = row['peptide_num'] - result_rows.append((row[taxon_col], new_func, split_row)) - - # create a new multi index - new_index = pd.MultiIndex.from_tuples([(tax, func) for tax, func, _ in result_rows], names=[taxon_col, func_col]) - new_data = pd.DataFrame([split_row for _, _, split_row in result_rows], index=new_index) - # drop the taxon and func columns - new_data.drop(columns=[taxon_col, func_col], inplace=True) - # move the peptide_num to the first column if it exists - new_data = new_data[['peptide_num'] + [col for col in new_data.columns if col != 'peptide_num']] - + result_rows.append(split_row) + # creeate a new df + new_data = pd.DataFrame(result_rows) + + #groupby taxon and func and sum the sample intensity + new_data = new_data.groupby([taxon_col, func_col]).sum(numeric_only=True) + + return new_data diff --git a/metax/utils/version.py b/metax/utils/version.py index 6ecb2a8..a3ad0ac 100644 --- a/metax/utils/version.py +++ b/metax/utils/version.py @@ -1,2 +1,2 @@ -__version__ = '1.111.0' +__version__ = '1.111.1' API_version = '2' \ No newline at end of file diff --git a/pyproject.toml b/pyproject.toml index 486194d..659a117 100644 --- a/pyproject.toml +++ b/pyproject.toml @@ -4,7 +4,7 @@ build-backend = "setuptools.build_meta" [project] name = "MetaXTools" -version = "1.111.0" +version = "1.111.1" description = "MetaXTools is a novel tool for linking peptide sequences with taxonomic and functional information in Metaproteomics." readme = "README_PyPi.md" license = { text = "NorthOmics" } From 8171cf233e511c2662f71773048a0f8610edabe1 Mon Sep 17 00:00:00 2001 From: Qing Date: Wed, 21 Aug 2024 00:49:28 -0400 Subject: [PATCH 3/7] - Fix: Fixed the bug when restore the object, the seetings was not restored completely. --- Docs/ChangeLog.md | 6 ++++++ metax/gui/main_gui.py | 17 +++++++++++++++++ metax/utils/version.py | 2 +- pyproject.toml | 2 +- 4 files changed, 25 insertions(+), 2 deletions(-) diff --git a/Docs/ChangeLog.md b/Docs/ChangeLog.md index b2baffa..6329d29 100644 --- a/Docs/ChangeLog.md +++ b/Docs/ChangeLog.md @@ -1,3 +1,9 @@ +# Version: 1.111.2 +## Date: 2024-08-21 +### Changes: +- Fix: Fixed the bug when restore the object, the seetings was not restored completely. + + # Version: 1.111.1 ## Date: 2024-08-21 ### Changes: diff --git a/metax/gui/main_gui.py b/metax/gui/main_gui.py index be063e5..438aaf0 100644 --- a/metax/gui/main_gui.py +++ b/metax/gui/main_gui.py @@ -1175,6 +1175,12 @@ def save_set_multi_table_settings(self): elif isinstance(widget, QtWidgets.QSpinBox): self.settings.setValue(f"{settings_key}/value", widget.value()) + + elif isinstance(widget, QtWidgets.QCheckBox): + self.settings.setValue(f"{settings_key}/isChecked", widget.isChecked()) + + elif isinstance(widget, QtWidgets.QLineEdit): + self.settings.setValue(f"{settings_key}/text", widget.text()) def export_log_file(self): @@ -1251,6 +1257,17 @@ def restore_settings_after_load_taxafunc_obj(self): elif isinstance(widget, QtWidgets.QSpinBox): value = self.settings.value(f"{settings_key}/value", 0, type=int) widget.setValue(value) + elif isinstance(widget, QtWidgets.QCheckBox): + checked = self.settings.value(f"{settings_key}/isChecked", False, type=bool) + widget.setChecked(checked) + if widget.objectName() == 'checkBox_set_taxa_func_split_func': + enable_list = [self.lineEdit_set_taxa_func_split_func_sep, self.checkBox_set_taxa_func_split_func_share_intensity] + for w in enable_list: + w.setEnabled(checked) + + elif isinstance(widget, QtWidgets.QLineEdit): + text = self.settings.value(f"{settings_key}/text", "", type=str) + widget.setText(text) # enable button after multi table is set diff --git a/metax/utils/version.py b/metax/utils/version.py index a3ad0ac..45b4501 100644 --- a/metax/utils/version.py +++ b/metax/utils/version.py @@ -1,2 +1,2 @@ -__version__ = '1.111.1' +__version__ = '1.111.2' API_version = '2' \ No newline at end of file diff --git a/pyproject.toml b/pyproject.toml index 659a117..d240d3a 100644 --- a/pyproject.toml +++ b/pyproject.toml @@ -4,7 +4,7 @@ build-backend = "setuptools.build_meta" [project] name = "MetaXTools" -version = "1.111.1" +version = "1.111.2" description = "MetaXTools is a novel tool for linking peptide sequences with taxonomic and functional information in Metaproteomics." readme = "README_PyPi.md" license = { text = "NorthOmics" } From 698d65b83ce527af5a76058bc297d9fe0b60cc02 Mon Sep 17 00:00:00 2001 From: Qing <44231502+byemaxx@users.noreply.github.com> Date: Wed, 21 Aug 2024 11:00:42 -0400 Subject: [PATCH 4/7] - New: Added protein_id as a function to the OTF table, only keep the first protein_id as the function. --- Docs/ChangeLog.md | 5 + metax/data/example_data/Example_OTF.tsv | 10002 +++++++++---------- metax/peptide_annotator/pep_to_taxafunc.py | 11 +- metax/utils/version.py | 2 +- pyproject.toml | 2 +- 5 files changed, 5017 insertions(+), 5005 deletions(-) diff --git a/Docs/ChangeLog.md b/Docs/ChangeLog.md index 6329d29..5b83d48 100644 --- a/Docs/ChangeLog.md +++ b/Docs/ChangeLog.md @@ -1,3 +1,8 @@ +# Version: 1.111.3 +## Date: 2024-08-21 +### Changes: +- New: Added protein_id as a function to the OTF table, only keep the first protein_id as the function. + # Version: 1.111.2 ## Date: 2024-08-21 ### Changes: diff --git a/metax/data/example_data/Example_OTF.tsv b/metax/data/example_data/Example_OTF.tsv index d2980fe..81db608 100644 --- a/metax/data/example_data/Example_OTF.tsv +++ b/metax/data/example_data/Example_OTF.tsv @@ -1,5001 +1,5001 @@ -Sequence Proteins LCA_level Taxon Taxon_prop eggNOG_OGs eggNOG_OGs_prop max_annot_lvl max_annot_lvl_prop COG_category COG_category_prop eggNOG_Description eggNOG_Description_prop Gene Gene_prop GOs GOs_prop EC EC_prop KEGG_ko KEGG_ko_prop KEGG_Pathway KEGG_Pathway_prop KEGG_Module KEGG_Module_prop KEGG_Reaction KEGG_Reaction_prop KEGG_rclass KEGG_rclass_prop BRITE BRITE_prop KEGG_TC KEGG_TC_prop CAZy CAZy_prop BiGG_Reaction BiGG_Reaction_prop PFAMs PFAMs_prop dbcan_EC dbcan_EC_prop dbcan_HMMER dbcan_HMMER_prop dbcan_eCAMI dbcan_eCAMI_prop dbcan_DIAMOND dbcan_DIAMOND_prop EC_DE EC_AN EC_CC EC_CA EC_DE_prop EC_AN_prop EC_CC_prop EC_CA_prop KEGG_Pathway_name KEGG_Pathway_name_prop None None_prop Intensity_V1_01 Intensity_V1_02 Intensity_V1_03 Intensity_V1_04 Intensity_V1_05 Intensity_V1_06 Intensity_V1_07 Intensity_V1_08 Intensity_V1_09 Intensity_V1_10 Intensity_V1_11 Intensity_V1_12 Intensity_V1_13 Intensity_V1_14 Intensity_V1_15 Intensity_V1_16 Intensity_V1_17 Intensity_V1_18 Intensity_V1_19 Intensity_V1_20 Intensity_V1_21 Intensity_V1_22 Intensity_V1_23 Intensity_V1_24 Intensity_V1_25 Intensity_V1_26 Intensity_V1_27 Intensity_V1_28 Intensity_V1_29 Intensity_V1_30 Intensity_V1_31 Intensity_V1_32 Intensity_V1_33 Intensity_V1_34 Intensity_V1_35 Intensity_V1_36 Intensity_V1_37 Intensity_V1_38 Intensity_V2_01 Intensity_V2_02 Intensity_V2_03 Intensity_V2_04 Intensity_V2_05 Intensity_V2_06 Intensity_V2_07 Intensity_V2_08 Intensity_V2_09 Intensity_V2_10 Intensity_V2_11 Intensity_V2_12 Intensity_V2_13 Intensity_V2_14 Intensity_V2_15 Intensity_V2_16 Intensity_V2_17 Intensity_V2_18 Intensity_V2_19 Intensity_V2_20 Intensity_V2_21 Intensity_V2_22 Intensity_V2_23 Intensity_V2_24 Intensity_V2_25 Intensity_V2_26 Intensity_V2_27 Intensity_V2_28 Intensity_V2_29 Intensity_V2_30 Intensity_V2_31 Intensity_V2_32 Intensity_V2_33 Intensity_V2_34 Intensity_V2_35 Intensity_V2_36 Intensity_V2_37 Intensity_V2_38 Intensity_V3_01 Intensity_V3_02 Intensity_V3_03 Intensity_V3_04 Intensity_V3_05 Intensity_V3_06 Intensity_V3_07 Intensity_V3_08 Intensity_V3_09 Intensity_V3_10 Intensity_V3_11 Intensity_V3_12 Intensity_V3_13 Intensity_V3_14 Intensity_V3_15 Intensity_V3_16 Intensity_V3_17 Intensity_V3_18 Intensity_V3_19 Intensity_V3_20 Intensity_V3_21 Intensity_V3_22 Intensity_V3_23 Intensity_V3_24 Intensity_V3_25 Intensity_V3_26 Intensity_V3_27 Intensity_V3_28 Intensity_V3_29 Intensity_V3_30 Intensity_V3_31 Intensity_V3_32 Intensity_V3_33 Intensity_V3_34 Intensity_V3_35 Intensity_V3_36 Intensity_V3_37 Intensity_V3_38 Intensity_V4_01 Intensity_V4_02 Intensity_V4_03 Intensity_V4_04 Intensity_V4_05 Intensity_V4_06 Intensity_V4_07 Intensity_V4_08 Intensity_V4_09 Intensity_V4_10 Intensity_V4_11 Intensity_V4_12 Intensity_V4_13 Intensity_V4_14 Intensity_V4_15 Intensity_V4_16 Intensity_V4_17 Intensity_V4_18 Intensity_V4_19 Intensity_V4_20 Intensity_V4_21 Intensity_V4_22 Intensity_V4_23 Intensity_V4_24 Intensity_V4_25 Intensity_V4_26 Intensity_V4_27 Intensity_V4_28 Intensity_V4_29 Intensity_V4_30 Intensity_V4_31 Intensity_V4_32 Intensity_V4_33 Intensity_V4_34 Intensity_V4_35 Intensity_V4_36 Intensity_V4_37 Intensity_V4_38 Intensity_V5_01 Intensity_V5_02 Intensity_V5_03 Intensity_V5_04 Intensity_V5_05 Intensity_V5_06 Intensity_V5_07 Intensity_V5_08 Intensity_V5_09 Intensity_V5_10 Intensity_V5_11 Intensity_V5_12 Intensity_V5_13 Intensity_V5_14 Intensity_V5_15 Intensity_V5_16 Intensity_V5_17 Intensity_V5_18 Intensity_V5_19 Intensity_V5_20 Intensity_V5_21 Intensity_V5_22 Intensity_V5_23 Intensity_V5_24 Intensity_V5_25 Intensity_V5_26 Intensity_V5_27 Intensity_V5_28 Intensity_V5_29 Intensity_V5_30 Intensity_V5_31 Intensity_V5_32 Intensity_V5_33 Intensity_V5_34 Intensity_V5_35 Intensity_V5_36 Intensity_V5_37 Intensity_V5_38 -(3sulfo)DNTEELIALIK MGYG000000245_00850 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp003470905|m__MGYG000000245 1.0 COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Saccharopine dehydrogenase 1.0 LYS1 1.0 - 1.0 1.5.1.7 1.0 ko:K00290 1.0 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 1.0 M00030,M00032 1.0 R00715 1.0 RC00217,RC01532 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Sacchrp_dh_C,Sacchrp_dh_NADP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 saccharopine dehydrogenase (NAD(+), L-lysine-forming). lysine-2-oxoglutarate reductase. - H2O + L-saccharopine + NAD(+) = 2-oxoglutarate + H(+) + L-lysine + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Lysine degradation;Lysine biosynthesis;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1765523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6840189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(AccQTag)DGPMPQTNEHVLLAR MGYG000004756_01173;MGYG000003279_00951;MGYG000004658_01205;MGYG000001562_01075 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76460 0 69417 0 0 0 0 383638 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143519 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87296 0 0 0 0 0 0 0 0 0 5068132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3037157 0 3672570 0 0 0 0 4889995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(AccQTag)TINTSHVEYQTANR MGYG000000042_01421;MGYG000004756_01173;MGYG000001415_02515;MGYG000002438_02321;MGYG000004658_01205;MGYG000000053_00908;MGYG000000243_01988;MGYG000000013_02251;MGYG000004006_00433;MGYG000001562_01075;MGYG000000074_01773;MGYG000001789_00154;MGYG000003279_00951;MGYG000000273_00431;MGYG000004763_01689;MGYG000001302.1_00073;MGYG000000170_00073 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 0.5882352941176471 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 586816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1043981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 561090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 890400 0 0 0 0 0 0 0 -(Acetyl)AAATAADKAR MGYG000004733_00775;MGYG000001338_01157;MGYG000000133_00993;MGYG000000301_01128 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 214580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 688707 0 0 0 0 0 0 0 0 0 0 675135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324053 0 0 0 0 538170 -(Acetyl)AADIVLQAAIAAGAPK MGYG000002323_02346;MGYG000000093_03243;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206;MGYG000002534_02768;MGYG000003883_03730 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.8571428571428571 1236|Gammaproteobacteria 1.0 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.8571428571428571 adhE 1.0 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)AAFEEAEHAAK MGYG000003509_00509;MGYG000000177_00118;MGYG000002026_00456;MGYG000003891_00390;MGYG000004769_01404;MGYG000000198_03730;MGYG000000172_04155;MGYG000004087_01663;MGYG000001434_00926;MGYG000000198_03710;MGYG000004087_01662;MGYG000001564_01103;MGYG000001311_01511;MGYG000001493_02801;MGYG000001493_02800;MGYG000003422_00075;MGYG000004713_00792 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,21YU6@1506553|Lachnoclostridium 0.5294117647058824 186801|Clostridia 0.8823529411764706 C 1.0 Rubrerythrin 0.6470588235294118 rbr3A 0.9411764705882353 - 0.9411764705882353 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.8823529411764706 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1589317 0 0 1239462 0 0 0 0 1771893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)AAVDATAVSPEELQAK MGYG000003683_00301;MGYG000000756_01431;MGYG000001490_01143 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 Pyruvate formate lyase-like 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bac_luciferase,Fer4_12,Gly_radical,PFL-like,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 773174 0 0 767183 448469 0 0 0 0 0 0 0 0 518037 0 278973 0 0 0 608751 431729 297121 0 0 478416 775435 0 0 354280 420517 382973 595021 0 0 0 495970 0 0 491081 0 0 383912 560300 0 0 0 0 0 0 0 0 991086 0 1953029 0 0 0 411717 390772 924994 0 0 467644 1091307 0 0 770886 379829 0 484333 0 0 0 525670 0 0 299097 0 0 478644 425698 0 0 0 0 0 0 0 0 513521 0 340738 0 0 0 321446 524084 409856 0 0 708519 500912 0 0 509446 572264 846166 335292 0 0 0 416130 0 0 295336 0 0 0 0 0 0 0 0 0 0 0 0 536637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340756 0 0 1069057 0 0 765116 1472911 0 0 0 0 0 0 0 0 968217 0 824316 0 0 0 641311 850234 1001691 0 0 308567 822590 0 0 1244482 768849 598786 467915 0 0 0 457288 -(Acetyl)AAYSSGKPALGVGAGNTPVIIDDTADVK MGYG000001607_02072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_B|s__Dorea_B phocaeensis|m__MGYG000001607 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4161765 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)ACDKHLTEAFASAGLDSGSNWR MGYG000002670_01817 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp900546625|m__MGYG000002670 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,25VT8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 578792 0 215992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)ADADIASDDAIKK MGYG000000212_00409 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG1879@1|root,COG1879@2|Bacteria,1TRBC@1239|Firmicutes,24DQX@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 798780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1724535 0 0 0 0 0 0 1429355 0 0 0 0 0 0 0 0 0 0 0 2028680 0 0 0 0 0 902282 0 0 0 0 0 0 0 0 0 0 1322958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 862225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1020591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 636192 0 0 0 0 0 0 0 0 0 0 408871 0 -(Acetyl)AEAEDGYALK MGYG000000133_01438 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3WISX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035,ko:K13889 1.0 ko02010,ko02024,map02010,map02024 1.0 M00239,M00348 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.11 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 1.0 none 1.0 0 0 113828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1035240 0 0 0 0 351493 -(Acetyl)AEKNVEVIDKESK MGYG000002517_01393 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia 1.0 186801|Clostridia 1.0 NT 1.0 PFAM CheW domain protein 1.0 - 1.0 - 1.0 - 1.0 ko:K03408 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 265309 0 0 0 0 444544 0 0 0 0 0 0 93126 0 0 0 0 0 0 0 0 0 0 191785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1033225 0 288363 0 0 0 0 1374348 1487389 0 0 717464 0 1310631 1614033 0 0 0 1360137 0 0 0 0 0 1496974 1276268 1402839 0 0 0 0 0 438866 771690 1059150 0 1341284 294451 0 0 880818 0 0 0 0 0 0 0 0 575258 0 0 454520 0 0 0 0 0 0 0 0 0 0 604672 388554 0 0 0 0 0 648090 0 0 0 0 752760 -(Acetyl)AEVEADLNTLK(Xlink_BuUrBu[213]) MGYG000000179_03775 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,21Y9B@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 506604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460804 0 0 0 0 0 0 493151 0 555919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1166024 0 0 0 0 0 0 0 640261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1225519 0 0 768065 0 0 0 0 658409 0 0 0 0 0 0 0 0 0 0 1117274 0 0 0 0 0 0 0 0 752290 0 886018 0 0 0 0 903166 0 0 3236265 0 0 3146181 0 0 0 0 1070232 0 0 0 0 0 0 0 0 0 0 5298264 0 5910386 0 0 0 0 0 0 1773916 0 8081219 0 0 0 0 2772530 -(Acetyl)AGVKPEQVDEVLM(Oxidation)GC(Carbamidomethyl)VIQAAQGQNVAR MGYG000001711_01126;MGYG000002517_00540 domain d__Bacteria 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,3VP0M@526524|Erysipelotrichia 0.5 526524|Erysipelotrichia 0.5 I 1.0 Thiolase, C-terminal domain 0.5 - 0.5 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1011847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)AGVKPEQVDEVLMGC(Carbamidomethyl)VIQAAQGQNVAR MGYG000001711_01126;MGYG000002517_00540 domain d__Bacteria 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,3VP0M@526524|Erysipelotrichia 0.5 526524|Erysipelotrichia 0.5 I 1.0 Thiolase, C-terminal domain 0.5 - 0.5 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)AHIEKQAGELQEK MGYG000002515_03186 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia fergusonii|m__MGYG000002515 1.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,3WV8F@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)AIADLDKQPDSVSSVLK MGYG000002504_02331;MGYG000002494_03392 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 2D4RX@1|root,2SW2Q@2759|Eukaryota 0.5 2759|Eukaryota 0.5 S 0.5 helix_turn_helix isocitrate lyase regulation 0.5 - 0.5 - 0.5 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 HTH_IclR,IclR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1221210 0 0 0 1599123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1750921 0 0 0 0 1994325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 883762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1233190 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379092 0 0 0 0 0 0 0 0 0 -(Acetyl)AILATAQEC(Carbamidomethyl)NSPVILGVSEGAGK MGYG000003335_01155 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__GCA-900066135|s__GCA-900066135 sp900543575|m__MGYG000003335 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZ5J@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)AKEKFDR MGYG000004756_01173;MGYG000001415_02515;MGYG000002438_02321;MGYG000004658_01205;MGYG000004288_00862;MGYG000002972_00178;MGYG000003516_01606;MGYG000003542_01415;MGYG000001562_01075;MGYG000000045_02616;MGYG000000254_02569;MGYG000000074_01773;MGYG000003279_00951;MGYG000001470_03722;MGYG000000044_01721;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000000223_03134;MGYG000001400_03001 life d__Bacteria 0.9474 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 0.47368421052631576 976|Bacteroidetes 0.631578947368421 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.8421052631578947 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.9473684210526315 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)AKEKFER MGYG000000042_01421;MGYG000002106_00224;MGYG000001524_01606;MGYG000001630_01142;MGYG000002485_02622;MGYG000004893_01944;MGYG000004893_00932;MGYG000003460_01161;MGYG000003155_00314;MGYG000001925_01419;MGYG000000273_00431;MGYG000001701_00473;MGYG000004763_01689;MGYG000003681_02037;MGYG000001384_04567;MGYG000001464_00103;MGYG000002281_02290;MGYG000003185_01074;MGYG000003992_01709;MGYG000003142_01879;MGYG000002528_01098;MGYG000001313_00097;MGYG000000013_02251;MGYG000003266_00392;MGYG000003583_01411;MGYG000002455_03884;MGYG000000348_00283;MGYG000003628_01000;MGYG000001485_02164;MGYG000000034_01346;MGYG000001141_02439;MGYG000002930_00867;MGYG000003142_01865;MGYG000000196_03974;MGYG000003375_00698;MGYG000004573_00004;MGYG000001661_02666;MGYG000003851_00676;MGYG000002762_01733;MGYG000000121_02189;MGYG000001789_00154;MGYG000001567_01738;MGYG000000182_00585;MGYG000000054_03933;MGYG000000236_01807;MGYG000000098_02017;MGYG000002291_02272;MGYG000003185_01053;MGYG000002556_01332;MGYG000000036_01380;MGYG000000445_01370;MGYG000001346_01533;MGYG000000243_01988;MGYG000001780_03476;MGYG000002540_03367;MGYG000001646_01118;MGYG000003073_01160;MGYG000003514_00785;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.23728813559322035 976|Bacteroidetes 0.4915254237288136 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9830508474576272 tuf 1.0 - 0.847457627118644 - 1.0 ko:K02358 0.9830508474576272 - 0.9830508474576272 - 0.9830508474576272 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9830508474576272 - 0.9830508474576272 - 1.0 - 0.9491525423728814 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9830508474576272 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)AKEKYER MGYG000000756_01285 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium sp002742445|m__MGYG000000756 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)AMNADGTINRAALPAIFNPEDLNALEQALR MGYG000000243_00603 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,4AN6T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG2086 Electron transfer flavoprotein beta subunit 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)ASTIFPSFVGHTFAVHDGR MGYG000000099_02397 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3WJ9F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA 1.0 rpsS 1.0 - 1.0 - 1.0 ko:K02965 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)CIEEIGTYDPTKDPSEYHVNEELAK MGYG000002492_01364;MGYG000000154_00276;MGYG000002517_01931;MGYG000004719_01372;MGYG000000271_00791;MGYG000004271_01605;MGYG000000489_02523;MGYG000002670_00836 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 - 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295652 0 482584 0 0 0 0 0 0 0 636182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 846080 568705 0 0 0 0 0 0 0 0 0 0 641349 0 0 0 0 0 0 0 0 0 565674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286571 588527 0 0 0 0 0 0 0 0 0 0 414838 0 -(Acetyl)DEAEEKNLR MGYG000004735_01252 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0747@1|root,COG0747@2|Bacteria,1VSRH@1239|Firmicutes,24Y1D@186801|Clostridia,263KC@186807|Peptococcaceae 1.0 186801|Clostridia 1.0 E 1.0 extracellular solute-binding protein, family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 672888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)EADPAAQFEGLK MGYG000000301_01318 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900541985|m__MGYG000000301 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183303 0 0 0 0 0 0 0 314274 0 0 0 0 0 240320 0 0 0 0 0 0 0 0 208308 0 196040 0 0 0 0 0 0 839756 1915559 0 0 778581 1251309 1135035 0 0 0 0 0 1429348 0 499378 0 0 0 0 0 1449091 0 1043388 0 0 0 0 1282282 0 924949 0 3879645 0 0 0 0 1384278 -(Acetyl)EEKEVTKPEK MGYG000003891_01624 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG1653@1|root,COG1653@2|Bacteria,1TW09@1239|Firmicutes,24BZW@186801|Clostridia,36G3C@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K17318 1.0 ko02010,map02010 1.0 M00603 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.29,3.A.1.1.9 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2044025 0 0 0 0 1911326 0 0 0 0 1879315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1139474 0 0 0 0 0 0 0 0 0 773022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)EENAELLPGGGSK MGYG000000002_03137 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A faecis|m__MGYG000000002 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439,ko:K17202 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212,M00590 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 1042388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235491 0 668315 0 0 0 0 0 360247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176215 0 0 0 0 0 740974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)EGTFTPADSYDVGER MGYG000003891_00348 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG4166@1|root,COG4166@2|Bacteria 1.0 2|Bacteria 1.0 E 1.0 transmembrane transport 1.0 - 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 BACON,DUF4374,DUF4488,DUF5011,F5_F8_type_C,M60-like_N,Peptidase_M60,SBP_bac_5,Sulfatase,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 513947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1311449 0 0 0 0 2144027 0 0 0 0 1911931 0 0 0 0 470425 0 0 0 0 427336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)EGVANKDKPLVWFNR MGYG000004735_00164 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7513173 0 0 0 0 0 0 0 1975768 0 0 0 976119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)EITSIVDGPISGEVK MGYG000000213_03703;MGYG000001617_04130;MGYG000000077_02122;MGYG000000262_01857;MGYG000000153_01716;MGYG000004785_01105;MGYG000002312_00278;MGYG000000159_02953;MGYG000000135_04104;MGYG000000179_02421;MGYG000004891_03103;MGYG000002492_02243;MGYG000003695_03041;MGYG000003500_00962;MGYG000004879_02429;MGYG000000153_02578;MGYG000001186_00767;MGYG000001338_02857;MGYG000000133_02555;MGYG000004548_00336;MGYG000004296_01841 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,3XYWX@572511|Blautia 0.38095238095238093 186801|Clostridia 1.0 H 0.9047619047619048 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1389758 0 0 0 1535233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 731669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)FTSGNC(Carbamidomethyl)YGIIGAN(Deamidated)GAGK MGYG000003363_03180;MGYG000004876_03090;MGYG000004899_00018;MGYG000000196_03902;MGYG000001313_01281;MGYG000001346_02987;MGYG000000236_01135 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,2FMW7@200643|Bacteroidia,4AKW8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ABC_tran,ABC_tran_Xtn 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)GEEGGAGVAKEDLK MGYG000004733_00545 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia,3Y2EG@572511|Blautia 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate-binding protein PnrA-like 1.0 - 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1184458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)GGGVRPGFEGGQM(Oxidation)PLFR MGYG000003368_00842 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Tissierellales|f__Peptoniphilaceae|g__Finegoldia|s__Finegoldia sp900766215|m__MGYG000003368 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,22HCT@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3876412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)GGGVRPGFEGGQMPLYR MGYG000002528_01858;MGYG000000028_01603 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,268S2@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3695107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)GKVAPDFELVK MGYG000000196_04914 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1532316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)ILTGAGQKSFVAGADIGEMSTLTK MGYG000001809_02346 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eisenbergiella|s__|m__MGYG000001809 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,36EDS@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 1.0 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1343649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224456 0 0 0 0 0 0 0 -(Acetyl)IYYQSDC(Carbamidomethyl)NLSLLDGK MGYG000000187_00168 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,25VBQ@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 708681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KAALIER MGYG000003899_00855 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539945|m__MGYG000003899 1.0 COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,3WGG6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O 1.0 hcp 1.0 - 1.0 1.7.99.1 1.0 ko:K05601 1.0 ko00910,map00910 1.0 - 1.0 R00143 1.0 RC02797 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Prismane 1.0 - 1.0 - 1.0 - 1.0 - 1.0 hydroxylamine reductase. hydroxylamine (acceptor) reductase. Reduced pyocyanine, methylene blue and flavins act as donors for the reduction of hydroxylamine.-!-May be identical to EC 1.7.2.1. A + H2O + NH4(+) = AH2 + H(+) + hydroxylamine. 1.0 1.0 1.0 1.0 Nitrogen metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 559637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KAEGGIER MGYG000000142_02504;MGYG000001338_02427;MGYG000000184_00683;MGYG000000184_00682;MGYG000000201_00496 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3XZDK@572511|Blautia 0.4 186801|Clostridia 1.0 C 1.0 acetyl-CoA decarbonylase synthase complex subunit beta 0.6 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 162393 0 0 0 0 0 0 0 0 0 0 0 0 0 960545 0 0 0 0 0 0 509083 0 0 0 0 0 0 0 0 0 0 0 0 1064367 0 0 0 1839741 0 0 0 0 0 0 0 0 0 0 0 0 0 1623087 0 0 0 0 0 0 481455 0 1238831 0 1324331 0 0 0 0 0 0 0 0 1804836 1877670 1524429 0 1672282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363856 0 1366772 0 0 0 0 0 0 0 0 1164435 1245235 1029536 0 2328944 0 0 0 0 0 0 0 0 0 0 0 0 0 1960383 0 0 0 0 0 0 0 0 3003223 0 0 0 0 0 0 0 0 0 0 2009363 2244257 1727692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KAGHYAVGQFNINNLEWTK MGYG000000142_01854;MGYG000000249_00065;MGYG000000258_00162;MGYG000001637_01196;MGYG000001374_02205;MGYG000002528_01756 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia 0.5 186801|Clostridia 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 0.8333333333333334 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1216331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KAPAAPK MGYG000004757_01023 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__UBA6398|s__UBA6398 sp900555645|m__MGYG000004757 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KEGHYAVGQFNINNLEWTK MGYG000001186_01756 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp900547695|m__MGYG000001186 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 1263256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KELLGK MGYG000001346_01043;MGYG000000196_00547;MGYG000004876_02935;MGYG000003681_00897;MGYG000002720_01363;MGYG000004797_02532;MGYG000000243_01228;MGYG000002478_02960;MGYG000001602_01322 domain d__Bacteria 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 0.5555555555555556 976|Bacteroidetes 0.7777777777777778 J 0.6666666666666666 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 0.5555555555555556 rpsA 0.5555555555555556 - 0.8888888888888888 - 0.5555555555555556 ko:K02945 0.5555555555555556 ko03010,map03010 0.5555555555555556 M00178 0.5555555555555556 - 0.6666666666666666 - 0.6666666666666666 br01610,ko00000,ko00001,ko00002,ko03011 0.5555555555555556 - 1.0 - 1.0 - 0.8888888888888888 S1 0.5555555555555556 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.5555555555555556 0.5555555555555556 0.5555555555555556 0.5555555555555556 Ribosome 0.5555555555555556 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KEWGLGNINK MGYG000000781_01762 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900541515|m__MGYG000000781 1.0 COG0280@1|root,COG0280@2|Bacteria,4NGX5@976|Bacteroidetes,2FMKY@200643|Bacteroidia,4AK60@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625,ko:K13788 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6295341 0 0 0 0 0 0 0 0 0 0 0 0 7698257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KGAMAY(O-pinacolylmethylphosphonate)LK MGYG000003374_01704 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella bivia|m__MGYG000003374 1.0 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane 1.0 hppA 1.0 - 1.0 3.6.1.1 1.0 ko:K15987 1.0 ko00190,map00190 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 3.A.10.1 1.0 - 1.0 - 1.0 H_PPase,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 inorganic diphosphatase. pyrophosphate phosphohydrolase. Specificity varies with the source and with the activating metal ion.-!-The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9. cf. EC 7.1.3.1. diphosphate + H2O = H(+) + 2 phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 651210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KGGVEPQSETVW(Dioxidation)R MGYG000002994_01409;MGYG000001658_02289;MGYG000003142_01866;MGYG000001300_00281;MGYG000004769_00436;MGYG000002619_00484;MGYG000002926_00231;MGYG000000089_01902;MGYG000000377_01099;MGYG000000392_00967;MGYG000003937_01028;MGYG000002040_01211;MGYG000004471_00745;MGYG000000084_01999;MGYG000000099_01235;MGYG000002098_01617;MGYG000001255_01100;MGYG000004642_00845;MGYG000002641_00068;MGYG000000371_01542;MGYG000000118_01086;MGYG000000039_00482;MGYG000002173_00226;MGYG000002224_01124;MGYG000000022_02282;MGYG000001733_00476;MGYG000004221_01652;MGYG000004285_00598;MGYG000002143_01658;MGYG000002720_00091;MGYG000004482_01536;MGYG000002965_00479;MGYG000000036_01379;MGYG000001685_01865;MGYG000002057_01067;MGYG000002545_02503;MGYG000001157_01851;MGYG000000258_00265;MGYG000004475_00888;MGYG000000989_00159;MGYG000001651_00900;MGYG000004525_01293;MGYG000004707_00950 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.46511627906976744 186801|Clostridia 0.9302325581395349 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KGGVEPQSETVWR MGYG000002994_01409;MGYG000001658_02289;MGYG000003142_01866;MGYG000001300_00281;MGYG000004769_00436;MGYG000002619_00484;MGYG000002926_00231;MGYG000000089_01902;MGYG000000377_01099;MGYG000000392_00967;MGYG000003937_01028;MGYG000002040_01211;MGYG000004471_00745;MGYG000000084_01999;MGYG000000099_01235;MGYG000002098_01617;MGYG000001255_01100;MGYG000004642_00845;MGYG000002641_00068;MGYG000000371_01542;MGYG000000118_01086;MGYG000000039_00482;MGYG000002173_00226;MGYG000002224_01124;MGYG000000022_02282;MGYG000001733_00476;MGYG000004221_01652;MGYG000004285_00598;MGYG000002143_01658;MGYG000002720_00091;MGYG000004482_01536;MGYG000002965_00479;MGYG000000036_01379;MGYG000001685_01865;MGYG000002057_01067;MGYG000002545_02503;MGYG000001157_01851;MGYG000000258_00265;MGYG000004475_00888;MGYG000000989_00159;MGYG000001651_00900;MGYG000004525_01293;MGYG000004707_00950 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.46511627906976744 186801|Clostridia 0.9302325581395349 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 524044 0 0 0 0 0 0 11088508 0 0 0 0 0 0 0 0 0 0 10225856 0 0 0 7510769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5620292 4933531 8226102 5116219 0 6915845 0 6351751 0 6535331 0 0 0 6408865 5799244 0 5230126 0 0 0 9077869 0 0 0 7413564 6826617 6574068 0 0 7739908 6119342 6236851 5873368 0 7076971 7536952 7470122 6426953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KGLITVLSK MGYG000000281_03142 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnoclostridium_A|s__Lachnoclostridium_A sp003464085|m__MGYG000000281 1.0 COG1715@1|root,COG1715@2|Bacteria,1R5BT@1224|Proteobacteria,2U0MJ@28211|Alphaproteobacteria,2K7S3@204457|Sphingomonadales 1.0 204457|Sphingomonadales 1.0 V 1.0 Restriction endonuclease 1.0 - 1.0 - 1.0 - 1.0 ko:K07448 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02048 1.0 - 1.0 - 1.0 - 1.0 Mrr_cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9670300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KIALTLY(Tyr->Val)K MGYG000001464_01830 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium|s__Fusobacterium polymorphum|m__MGYG000001464 1.0 COG0220@1|root,COG1519@1|root,COG0220@2|Bacteria,COG1519@2|Bacteria,378F3@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 M 1.0 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA 1.0 trmB 1.0 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 1.0 2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 1.0 ko:K02527,ko:K03439 1.0 ko00540,ko01100,map00540,map01100 1.0 M00060,M00080 1.0 R04658,R05074,R09763 1.0 RC00009,RC00077,RC00247 1.0 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03016 1.0 - 1.0 GT30 1.0 - 1.0 Glycos_transf_N,Methyltransf_4 1.0 - 1.0 GT30 1.0 GT30 1.0 GT30 1.0 tRNA (guanine(46)-N(7))-methyltransferase. | lipid IVA 3-deoxy-D-manno-octulosonic acid transferase. | (Kdo)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase. | (Kdo)2-lipid IVA (2-8) 3-deoxy-D-manno-octulosonic acid transferase. | (Kdo)3-lipid IVA (2-4) 3-deoxy-D-manno-octulosonic acid transferase. tRNA guanine 7-methyltransferase. | lipid IVA KDO transferase. | Kdo transferase. The enzyme specifically methylates guanine(46) at N(7) in tRNA. | The enzyme from Escherichia coli is bifunctional and transfers two 3-deoxy-D-manno-oct-2-ulosonate residues to lipid IVA (cf. EC 2.4.99.13).-!-The monofunctional enzymes from Bordetella pertusis, Aquifex aeolicus and Haemophilus influenzae catalyze the transfer of a single 3-D- manno-oct-2-ulosonate residue from CMP-3-D-manno-oct-2-ulosonate to lipid IVA.-!-The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno- oct-2-ulosonate residues and generate genus-specific epitopes. | The enzyme from Escherichia coli is bifunctional and transfers two 3-deoxy-D-manno-oct-2-ulosonate residues to lipid IVA (cf. EC 2.4.99.12).-!-The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno- oct-2-ulosonate residues and generate genus-specific epitopes. | The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno- octulosonate residues and generate genus-specific epitopes. | The enzyme from Chlamydia psittaci transfers four KDO residues to lipid A, forming a branched tetrasaccharide with the structure alpha- KDO-(2,8)-[alpha-KDO-(2,4)]-alpha-KDO-(2,4)-alpha-KDO (cf. EC 2.4.99.12, EC 2.4.99.13 and EC 2.4.99.14). guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)- methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine. | a lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha- Kdo-(2->6)-lipid IVA + CMP + H(+). | an alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+). | alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta- D-manno-octulosonate = alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha- Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+). | alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate = alpha-Kdo-(2->8)-[alpha- Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+). 1.0 1.0 1.0 1.0 Metabolic pathways;Lipopolysaccharide biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1385782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KIETISK MGYG000001683_01572 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Frisingicoccus|s__|m__MGYG000001683 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,21XZX@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Formyltetrahydrofolate synthetase 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4576073 0 0 0 0 0 -(Acetyl)KLALNLR MGYG000001423_01460;MGYG000004714_00478;MGYG000004699_00365 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae 1.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,36EKQ@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 - 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KLTVLSK MGYG000004479_01006;MGYG000001783_01851;MGYG000002478_04546;MGYG000004797_02951;MGYG000001599_02324;MGYG000000243_00072;MGYG000000781_01199;MGYG000004763_02178 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,2FMXC@200643|Bacteroidia,4ANTX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family 1.0 lysS 1.0 - 1.0 6.1.1.6 1.0 ko:K04567 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03658 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DUF4332,tRNA-synt_2,tRNA_anti-codon 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine--tRNA ligase. lysyl-tRNA synthetase. - ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 709879 885023 842043 0 0 0 0 0 0 1027582 848331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 842674 793260 0 661839 0 0 1605569 1131753 0 629290 0 708724 910518 627413 742474 857641 0 0 0 0 0 0 758706 1085602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822070 607125 0 805398 0 0 859030 1010491 0 792579 0 759621 851218 832059 430313 811573 0 0 0 0 0 0 1032456 932548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 749431 807937 0 505991 0 0 463485 663701 0 805829 0 909247 756326 1146274 1505930 1484497 0 0 0 0 0 0 1608643 981259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1046750 1208903 0 1357420 0 0 1366358 1759303 0 1241380 0 1010399 1391388 297286 538439 449423 0 0 0 0 0 0 255014 371957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231983 87682 0 205028 0 0 447546 326559 0 303588 0 321296 440167 -(Acetyl)KLVDELIPAVK MGYG000000022_00458;MGYG000000039_00979 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 2118017 0 0 0 0 0 0 0 0 0 0 0 871948 0 0 0 0 0 0 1013105 0 1190529 0 0 1143051 0 0 0 0 0 0 0 0 0 1073115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153409 0 0 0 0 0 504879 0 398401 0 0 0 0 0 193227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KVDAM(Oxidation)NAAGDKSVIK MGYG000001319_01320 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,36E17@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KVEVTIPVK(Lys->Arg) MGYG000004719_00336 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900756925|m__MGYG000004719 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2733027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KVIPELDGK MGYG000004757_00364 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__UBA6398|s__UBA6398 sp900555645|m__MGYG000004757 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KVIPELN(Deamidated)GK MGYG000001562_00044;MGYG000002540_02142;MGYG000001643_00773;MGYG000004285_00359;MGYG000002478_03999;MGYG000003697_01698;MGYG000000086_02423;MGYG000001789_00244;MGYG000003372_00674;MGYG000000243_01331;MGYG000002506_01169;MGYG000004756_01346;MGYG000003202_00946;MGYG000002905_02083 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.35714285714285715 976|Bacteroidetes 0.7142857142857143 G 0.5714285714285714 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 0.8571428571428571 - 0.8571428571428571 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.8571428571428571 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040466 0 0 0 0 1310783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582414 0 0 0 0 0 0 0 0 0 1020092 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KVIPELNGK MGYG000001562_00044;MGYG000002540_02142;MGYG000001643_00773;MGYG000004285_00359;MGYG000002478_03999;MGYG000003697_01698;MGYG000000086_02423;MGYG000001789_00244;MGYG000003372_00674;MGYG000000243_01331;MGYG000002506_01169;MGYG000004756_01346;MGYG000003202_00946;MGYG000002905_02083 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.35714285714285715 976|Bacteroidetes 0.7142857142857143 G 0.5714285714285714 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 0.8571428571428571 - 0.8571428571428571 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.8571428571428571 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)KVLPELNGK MGYG000001789_00244;MGYG000001562_00044;MGYG000000243_01331;MGYG000002506_01169;MGYG000000375_01483;MGYG000002478_03999;MGYG000003819_01468;MGYG000004642_01190;MGYG000001415_02219;MGYG000003202_00946;MGYG000002494_01669 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.2727272727272727 976|Bacteroidetes 0.5454545454545454 G 0.6363636363636364 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 0.8181818181818182 - 0.8181818181818182 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.8181818181818182 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1398112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)LGTGQAVAFENIDKAPEER MGYG000000198_01165 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,21XMI@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)LLTGLPDAYGR MGYG000003683_00301;MGYG000000138_02765;MGYG000002057_00708;MGYG000002469_00869;MGYG000003420_01555;MGYG000002974_01425;MGYG000002727_01362;MGYG000001292_01825;MGYG000003452_00444;MGYG000000164_01790;MGYG000001617_02351;MGYG000001464_02452;MGYG000002438_01173;MGYG000002654_00807 domain d__Bacteria 1.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 0.2857142857142857 186801|Clostridia 0.42857142857142855 C 1.0 Pyruvate formate lyase-like 0.2857142857142857 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 0.7142857142857143 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 605358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)M(Oxidation)GIIIKPLVTEK MGYG000000013_02234;MGYG000001378_05025;MGYG000001345_04701;MGYG000002033_01881;MGYG000002549_02923;MGYG000002478_00797;MGYG000000138_02887;MGYG000002561_02177;MGYG000001313_00072;MGYG000000243_01969;MGYG000000042_01089;MGYG000001346_01517;MGYG000000105_02006;MGYG000002455_03901;MGYG000000224_00474;MGYG000000098_02000;MGYG000003701_04696;MGYG000002438_02210;MGYG000003681_02053 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,2FT3A@200643|Bacteroidia,4ARB9@815|Bacteroidaceae 0.7894736842105263 976|Bacteroidetes 1.0 J 1.0 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome 1.0 rplW 1.0 - 1.0 - 1.0 ko:K02892 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 1137301 0 0 0 0 0 0 540516 996988 0 0 0 0 605421 0 904540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)M(Oxidation)ISAGDFR MGYG000000532_00439;MGYG000004735_00107;MGYG000000150_02633;MGYG000003335_00377;MGYG000001698_03996;MGYG000000095_00313;MGYG000000136_01173;MGYG000002445_00479;MGYG000000135_03339;MGYG000000359_00892;MGYG000004271_02006;MGYG000001315_00716;MGYG000001637_02148;MGYG000001688_01265;MGYG000000997_00192;MGYG000000153_00299;MGYG000004719_01278;MGYG000002025_02346;MGYG000000002_01173;MGYG000002989_00302;MGYG000001954_01282;MGYG000001617_04062;MGYG000000271_00872;MGYG000000141_00833;MGYG000000245_00761;MGYG000000389_00571;MGYG000003215_01007;MGYG000001367_01257;MGYG000001619_00509;MGYG000003702_00466;MGYG000000650_01785;MGYG000001247_00681;MGYG000002216_00086;MGYG000000179_03263;MGYG000002517_01016;MGYG000001065_01715;MGYG000000154_01060;MGYG000004548_01812;MGYG000000312_01121;MGYG000002247_02808 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 - 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 546658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 494544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)MDFTLDKK MGYG000000076_01275;MGYG000003694_00879;MGYG000000136_00900;MGYG000000312_02425;MGYG000000271_02102;MGYG000004271_00233;MGYG000000389_02149;MGYG000001793_01807;MGYG000002517_00542;MGYG000000489_01025 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.8 186801|Clostridia 1.0 C 0.8 acyl-CoA dehydrogenase 0.9 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 224556 0 0 0 0 0 0 270466 0 0 0 0 0 338828 476014 0 0 0 689682 616310 0 0 0 0 669778 0 318301 0 0 0 0 0 0 394690 218931 302398 432576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285590 0 0 0 0 0 219047 329982 0 0 0 736580 0 321178 366218 0 0 0 233097 366342 0 0 0 0 434427 274084 484743 0 0 0 0 0 0 171893 268094 0 668761 119842 2013481 702877 671255 0 1330157 871989 1078853 1983588 2075951 1072541 0 1425935 0 2572794 2475373 1160567 1722798 0 2060157 1905405 0 487349 0 527592 2118250 1865857 1932974 0 0 0 949886 0 1056953 1226312 1860626 1950900 2261208 822146 1332013 1069075 1822668 0 320023 1225563 1491651 979831 1445066 1874672 0 1695781 0 1791550 1722448 1538571 1647233 0 1523631 1761753 0 1100876 0 1039870 1647344 1097003 1550541 0 0 0 1243717 0 1653364 1374299 884707 1406180 1747393 1287046 -(Acetyl)MDLSNLQGAAGSTQSDNFR MGYG000002517_02854 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340200 0 0 0 0 0 0 0 0 0 0 436263 0 0 0 0 0 0 0 0 0 0 438330 0 0 0 0 0 0 0 0 0 0 0 0 483280 0 0 595785 0 0 0 0 0 0 0 0 0 0 461134 0 0 0 0 0 0 0 0 0 0 571504 0 0 -(Acetyl)MDTNSTITGR MGYG000002517_00557 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins 1.0 ribU 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ECF_trnsprt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726080 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)MINPIVK MGYG000004797_03519;MGYG000000098_03719;MGYG000000013_03985;MGYG000001306_02079;MGYG000001345_00516;MGYG000003693_00350;MGYG000000196_02452;MGYG000000042_02651;MGYG000001346_01624;MGYG000004185_01554;MGYG000002549_04587;MGYG000001337_03982;MGYG000003681_02801;MGYG000000243_02576;MGYG000000273_00377;MGYG000004763_01920;MGYG000002478_00894;MGYG000001364_02629;MGYG000000236_01868;MGYG000001378_04409 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 623029 0 0 0 0 0 0 0 0 0 0 0 0 0 414141 0 0 0 0 606434 0 0 0 0 504400 0 0 0 0 0 0 0 0 0 0 0 0 0 63677 0 0 0 0 0 0 0 0 0 0 0 0 0 607361 0 0 0 0 1029591 0 0 0 0 888703 0 0 0 0 0 0 0 0 0 0 0 0 0 427020 0 0 0 0 0 0 0 0 0 0 0 0 0 89497 0 0 0 0 368423 0 0 0 0 381060 0 0 0 0 0 0 0 0 0 0 0 0 0 102070 0 0 0 0 0 0 0 0 0 0 0 0 0 128067 0 0 0 0 139482 0 0 0 0 318464 0 0 0 0 0 0 0 0 0 0 0 0 0 467164 0 0 0 0 0 0 0 0 0 0 0 0 0 897981 0 0 0 0 725188 0 0 0 0 881159 0 0 0 0 0 0 0 0 0 0 -(Acetyl)MISAGDFK MGYG000000142_02218;MGYG000000077_00445 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3XZPQ@572511|Blautia 0.5 186801|Clostridia 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 - 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 813014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396952 0 0 0 0 0 0 0 0 1003019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1251117 0 0 0 0 0 0 0 0 1340575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488762 0 0 0 0 0 0 0 0 1441548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1237974 0 0 0 0 0 0 0 0 3278358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2228943 0 0 0 0 0 0 0 -(Acetyl)MISAGDFR MGYG000000532_00439;MGYG000004735_00107;MGYG000000150_02633;MGYG000003335_00377;MGYG000001698_03996;MGYG000000095_00313;MGYG000000136_01173;MGYG000002445_00479;MGYG000000135_03339;MGYG000000359_00892;MGYG000004271_02006;MGYG000001315_00716;MGYG000001637_02148;MGYG000001688_01265;MGYG000000997_00192;MGYG000000153_00299;MGYG000004719_01278;MGYG000002025_02346;MGYG000000002_01173;MGYG000002989_00302;MGYG000001954_01282;MGYG000001617_04062;MGYG000000271_00872;MGYG000000141_00833;MGYG000000245_00761;MGYG000000389_00571;MGYG000003215_01007;MGYG000001367_01257;MGYG000001619_00509;MGYG000003702_00466;MGYG000000650_01785;MGYG000001247_00681;MGYG000002216_00086;MGYG000000179_03263;MGYG000002517_01016;MGYG000001065_01715;MGYG000000154_01060;MGYG000004548_01812;MGYG000000312_01121;MGYG000002247_02808 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 - 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1816907 0 1695270 2099915 0 2126718 1383473 1782610 1930138 2309627 2021672 2889837 0 1610052 1859320 970476 1379272 0 1793133 0 0 1987855 0 1586426 1998078 2564274 1893235 0 2171940 1933280 1058183 0 1089389 1884052 1780933 1757048 1860483 1315164 715270 0 928368 826761 0 500900 821357 739224 642569 1036688 889967 1006033 0 777428 714831 752256 863064 0 609009 0 0 447883 0 591471 666080 889658 857188 0 1325975 1149076 771335 0 883443 840277 649840 710592 652568 692710 1704121 0 2349642 1304949 0 1106872 1277662 1601424 1537518 1326053 1871593 2035007 0 1878746 1531413 1849893 1683720 0 1270403 0 0 197415 0 1333832 1414656 1909452 1671686 0 1681185 1816479 1282091 0 2327411 1304081 1361997 1564201 1923192 2823580 2867747 0 1298484 3184451 0 1425609 1787384 3329717 3406085 2012363 2081358 1818494 0 3195792 3539053 1713105 2402068 0 2423761 0 0 960463 0 1052827 2738441 2448789 2942246 0 2682821 2732475 1701337 0 1634042 2472527 3007466 2701272 3668047 1335594 3661693 0 3220336 2939948 0 3318487 3155218 3061878 3977050 4351098 2255097 3105713 0 4041475 4031259 1997216 4156012 0 3225533 0 0 2924797 0 2780486 3409688 3825451 3739147 0 2345258 3294010 2689344 0 2403286 3194059 3337766 3841700 4814774 3006136 -(Acetyl)MKQDALGMIETK MGYG000003142_02726;MGYG000003142_02725 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium_J|s__Clostridium_J sp900547625|m__MGYG000003142 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 1.0 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)MVSAGDFR MGYG000000233_02473;MGYG000000205_01960 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,21Y5H@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 - 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 528297 0 0 0 0 0 0 0 0 541333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 503038 113686 0 0 0 0 0 0 0 0 0 0 495082 0 846965 0 0 0 0 0 0 0 0 1219737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 792199 715218 0 0 0 0 0 0 0 0 0 0 570657 0 459572 0 0 0 0 0 0 0 0 170297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517170 361414 0 0 0 0 0 0 0 0 0 0 327143 0 480707 0 0 0 0 0 0 0 0 653721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478793 372324 0 0 0 0 0 0 0 0 0 0 468837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114258 97421 0 0 0 0 0 0 0 0 0 0 139162 0 -(Acetyl)MVVQHNLTAM(Oxidation)NANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339173 0 0 0 0 0 0 0 863146 0 0 0 0 0 0 577525 0 484505 0 0 0 0 0 277305 0 0 0 0 460774 0 0 623623 0 0 0 0 0 0 0 0 0 296493 0 637719 482565 0 0 0 944543 0 751220 862884 0 0 0 0 0 0 0 0 0 949419 0 0 0 0 0 494369 0 1106971 0 0 0 0 0 0 995695 0 768314 484933 0 0 0 897544 951888 0 739896 0 792687 1281347 0 760360 1149988 1359125 0 870667 1161600 0 939383 1101115 0 0 0 1565957 909658 634495 0 715423 1092625 980767 0 0 0 0 1489840 0 1183113 1088477 875181 773250 1748768 1108013 -(Acetyl)MYEDETLVC(Carbamidomethyl)R MGYG000003891_00899 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,4H597@909932|Negativicutes 1.0 909932|Negativicutes 1.0 K 1.0 Probable zinc-ribbon domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-trcl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 900660 0 0 0 0 1109463 0 0 0 0 1204237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)NDSGVESIDDLAGKK MGYG000000133_01162 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3XYTF@572511|Blautia 1.0 186801|Clostridia 1.0 ET 1.0 COG COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain 1.0 artP 1.0 - 1.0 - 1.0 ko:K02029,ko:K02030 1.0 - 1.0 M00236 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1.3 1.0 - 1.0 - 1.0 SBP_bac_3,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822414 0 0 849417 0 784490 0 853460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521487 0 0 0 0 0 0 0 -(Acetyl)QLDEAQAGDNIGALLR MGYG000002492_00344;MGYG000002517_00205;MGYG000000245_03248;MGYG000002670_00364 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)QTENVLS(Ser->Gln)GK MGYG000000205_00061 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066535|m__MGYG000000205 1.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,268E5@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system 1.0 - 1.0 - 1.0 3.6.3.31 1.0 ko:K02052,ko:K11072 1.0 ko02010,ko02024,map02010,map02024 1.0 M00193,M00299 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 3.A.1.11,3.A.1.11.1 1.0 - 1.0 - 1.0 ABC_tran,TOBE_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ABC-type polyamine transporter. polyamine-transporting ATPase. An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.-!-Does not undergo phosphorylation during the transport process.-!-A bacterial enzyme that imports putrescine and spermidine.-!-In Escherichia coli the enzyme imports spermidine preferentially.-!-Formerly EC 3.6.3.31. ATP + H2O + polyamine-[polyamine-binding protein]Side 1 = ADP + phosphate + polyamineSide 2 + [polyamine-binding protein]Side 1. 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1368691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)SAFTGSASVM(Met->Xle)K MGYG000001789_02837 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002161565|m__MGYG000001789 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5902843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)SAGFLTR MGYG000002492_02720;MGYG000002517_00289;MGYG000000136_01618 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 1.0 rpsI 1.0 - 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3376203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)SATPGGVVK MGYG000003142_01853 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium_J|s__Clostridium_J sp900547625|m__MGYG000003142 1.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,36IUH@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome 1.0 rplN 1.0 - 1.0 - 1.0 ko:K02874 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L14 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3741545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3240583 0 0 0 0 0 0 0 0 0 0 3237371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)SEEHGPSSEAAPAWENYDAR MGYG000000133_00227 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,36EHU@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 Family 5 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236787 269007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1932880 2208960 0 0 0 827666 3331387 1490635 0 2723671 1797841 0 0 4763756 0 2229856 0 0 0 0 0 1417448 0 0 2310860 2002868 2649085 0 3925540 0 0 0 4476098 3268855 1898271 0 2617916 0 -(Acetyl)SEKDAAAEKTEESADETK MGYG000000133_00899 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1879@1|root,COG1879@2|Bacteria,1TSUI@1239|Firmicutes,24BR7@186801|Clostridia,26BK5@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K02058 1.0 - 1.0 M00221 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1.2 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 711720 0 0 0 1249046 0 0 1561327 0 869474 0 2727184 0 750884 0 0 2318378 0 1406274 0 0 0 0 0 0 0 0 0 0 0 1136521 1445174 0 0 0 802665 -(Acetyl)SEQNNTEMAFQIQR MGYG000002494_02265;MGYG000002535_04413;MGYG000002534_00127 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,3WXY5@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 U 1.0 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA 1.0 secB 1.0 GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 1.0 - 1.0 ko:K03071 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044,ko03110 1.0 3.A.5 1.0 - 1.0 - 1.0 SecB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 672549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502892 0 1036234 627246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1007973 0 0 754296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)SEQNNTEMTFQIQR MGYG000002506_03260;MGYG000002323_04108 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,3WXY5@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 U 1.0 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA 1.0 secB 1.0 GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 1.0 - 1.0 ko:K03071 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044,ko03110 1.0 3.A.5 1.0 - 1.0 - 1.0 SecB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 371351 0 0 0 741850 544630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424141 0 766857 0 0 0 0 463352 0 0 0 0 363469 0 0 0 0 0 413808 0 0 0 698033 866523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 434791 0 269176 0 0 0 0 287608 0 0 0 0 481546 0 0 0 0 0 225090 0 0 0 0 455472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519540 0 720941 0 0 0 0 382248 0 0 0 0 473983 0 0 0 0 0 581015 0 0 0 656327 612410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 926077 0 495141 0 0 0 0 374677 0 0 0 0 899561 0 0 0 0 0 0 0 0 0 0 177496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189763 0 0 0 0 356361 0 0 0 0 149662 0 0 0 0 -(Acetyl)SETNNTQER MGYG000003891_00998 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,25WUN@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA 1.0 rpsQ 1.0 - 1.0 - 1.0 ko:K02961 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 602947 0 0 0 0 630439 0 0 0 0 540059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)SHHHEGC(Carbamidomethyl)C(Carbamidomethyl)KHEGQPR MGYG000002506_02717 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3XNX9@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 K 1.0 transcriptional regulator 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 281194 319705 0 1583167 0 1042348 0 0 0 0 907270 0 0 0 725674 497056 427239 811898 0 0 0 0 0 0 287228 194607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67442 0 0 0 0 0 0 0 0 0 0 0 29381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35238 0 29950 0 0 0 0 16461 0 0 0 24085 29197 21619 11662 0 18667 0 0 0 0 38475 23384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)SKEKFER MGYG000000291_00377;MGYG000003184_03610;MGYG000002506_03686;MGYG000002506_02966 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,3ZITI@590|Salmonella 0.75 1236|Gammaproteobacteria 0.75 J 1.0 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.75 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 1964350 0 0 0 0 0 3904428 0 0 0 0 0 0 0 0 0 0 0 0 0 4287395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1351266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5751292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3574386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5505611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)SMSDDTHNSLSTGK MGYG000002494_01908 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0685@1|root,KOG0564@2759|Eukaryota 1.0 2759|Eukaryota 1.0 E 1.0 methylenetetrahydrofolate reductase (NAD(P)H) activity 1.0 MTHFR1 1.0 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.0 1.5.1.20,3.6.4.12 1.0 ko:K00297,ko:K10901 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko03440,ko03460,map00670,map00720,map01100,map01120,map01200,map01523,map03440,map03460 1.0 M00295,M00377,M00414 1.0 R01224,R07168 1.0 RC00081 1.0 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 1.0 - 1.0 - 1.0 - 1.0 BT1,DEAD,DUF1712,EamA,Helicase_C,Homoserine_dh,Hormone_recep,MTHFR,RecQ_Zn_bind,peroxidase,zf-C4 1.0 - 1.0 - 1.0 - 1.0 AA0 1.0 methylenetetrahydrofolate reductase [NAD(P)H]. | DNA helicase. MTHFR. A flavoprotein (FAD).-!-The enzyme catalyzes the reversible conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, playing an important role in folate metabolism by regulating the distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis.-!-This enzyme, characterized from Protozoan parasites of the genus Leishmania, is unique among similar characterized eukaryotic enzymes in that it lacks the C-terminal allosteric regulatory domain (allowing it to catalyze a reversible reaction) and uses NADH and NADPH with equal efficiency under physiological conditions. cf. EC 1.5.1.53, EC 1.5.1.54, and EC 1.5.7.1.-!-Formerly EC 1.1.1.68, EC 1.1.1.171, EC 1.1.99.15 and EC 1.7.99.5. | DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA.-!-Some of them unwind duplex DNA with a 3' to 5' polarity, other show 5' to 3' polarity or unwind DNA in both directions.-!-Some helicases unwind DNA as well as RNA.-!-May be identical with EC 3.6.4.13. (1) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH. (2) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH. | ATP + H2O = ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 Fanconi anemia pathway;Carbon metabolism;Homologous recombination;Carbon fixation pathways in prokaryotes;Metabolic pathways;Antifolate resistance;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 773241 1165052 1166439 0 0 1769198 0 0 677820 1030176 0 0 0 0 0 0 1366071 0 0 0 0 0 0 1875527 0 721648 0 0 1643524 0 0 0 1337991 0 0 0 706757 806767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)SNVIVKDNESLDSALR MGYG000001065_00121;MGYG000001954_00183;MGYG000001531_02509;MGYG000000087_00069;MGYG000001606_01557;MGYG000000255_00059;MGYG000002417_00179;MGYG000002445_00245 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 0.875 203691|Spirochaetes 0.875 L 0.875 PFAM Integrase core domain 0.875 - 0.875 - 1.0 - 1.0 ko:K07497 0.875 - 0.875 - 0.875 - 1.0 - 1.0 ko00000 0.875 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 0.875 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.875 none 1.0 0 0 590521 747026 579955 641708 472596 988508 807665 1052460 0 639235 534586 841685 660536 0 670218 0 793839 865206 568843 587031 0 738179 460105 792068 862263 0 1045333 717011 477151 510722 491040 732702 0 780570 514790 479275 812064 0 636558 1205948 591711 673546 719313 822081 814418 1417605 0 826180 1207445 981899 1035594 0 908762 0 811786 810015 705278 774416 0 610093 1138759 743359 1071319 0 1230096 797721 549448 915813 751293 964786 0 835342 752689 485081 488715 0 469879 904358 463982 473961 679803 426738 647618 420853 0 369179 294906 700618 541305 0 372099 0 419068 569880 539103 547650 0 541560 0 850615 336298 0 647869 468523 360735 308985 437860 474500 0 619355 347211 490797 378233 0 454170 358258 299031 600554 505252 529019 280561 637352 0 450888 358203 379452 527207 0 304802 0 537907 382375 632412 408390 0 464401 509346 407107 470279 0 227233 340168 411815 423090 571794 566185 0 453738 340881 308884 1220823 0 740933 1293594 784510 641336 551764 730558 1083590 1082485 0 808664 587978 1623973 1022518 0 1264827 0 871719 1570291 790081 459446 0 900174 743999 1359953 1175544 0 1564029 1118301 850653 345198 731963 1122752 0 1327606 1519141 1016076 -(Acetyl)SNVIVKDNESLDSALRR MGYG000001065_00121;MGYG000001954_00183;MGYG000001531_02509;MGYG000000087_00069;MGYG000000278_03375;MGYG000001606_01557;MGYG000000255_00059;MGYG000002417_00179;MGYG000002445_00245 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 0.7777777777777778 203691|Spirochaetes 0.7777777777777778 L 0.7777777777777778 PFAM Integrase core domain 0.7777777777777778 - 0.7777777777777778 - 1.0 - 1.0 ko:K07497 0.7777777777777778 - 0.7777777777777778 - 0.7777777777777778 - 1.0 - 1.0 ko00000 0.7777777777777778 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.7777777777777778 none 1.0 1337457 0 776717 0 675746 825261 745227 1087247 936550 1293068 786595 983458 705143 954305 724235 746583 948367 0 945852 1116136 996112 852502 0 838427 757849 1162540 1142027 0 984163 860250 665467 687098 641573 935547 0 211680 809674 598432 1497256 0 1189091 0 1130796 1521819 1413128 1534747 1276109 2768237 1568022 1138740 1893642 1997091 1766110 1938635 2055030 0 1241127 1455480 1670390 1362861 0 1131936 1653020 1532632 1753409 0 2287552 1192692 1098910 1468337 1232037 1947519 0 1788643 1695489 1004700 870404 0 716870 835558 684992 642699 516886 822017 804864 675736 617332 837503 715437 998852 658659 813773 570366 0 514933 828450 785914 0 0 656917 443964 842610 707849 0 1408409 859486 614722 509870 443077 774249 0 787678 642357 768589 799581 0 861580 887904 525226 1003516 658076 1047013 875074 1005882 644872 1017170 566580 795939 1034152 542094 766485 0 719573 551559 736916 742075 0 291049 876915 1015083 941387 0 391361 576276 0 755632 959399 1401313 0 1094215 843292 441354 2201590 0 1492020 2709301 0 1504042 1099159 1058467 2228073 2129671 1026388 1707947 939133 1588221 1714862 858147 2137125 0 1484022 1944353 1028179 1290101 0 1608085 1159269 2239339 1333963 0 2291418 1696606 1664944 890755 1200069 1515935 0 1993994 2292709 1584298 -(Acetyl)SNVIVKENESLDSALR MGYG000000187_00800;MGYG000002528_02821;MGYG000000193_00756;MGYG000000078_01046;MGYG000001319_00312;MGYG000003366_01669;MGYG000001543_03644 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 0.8571428571428571 203691|Spirochaetes 0.8571428571428571 L 0.8571428571428571 PFAM Integrase core domain 0.8571428571428571 - 0.8571428571428571 - 1.0 - 1.0 ko:K07497 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 1.0 - 1.0 ko00000 0.8571428571428571 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.8571428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1711591 0 0 0 0 1122306 0 0 0 0 1446285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 719214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469351 0 0 0 0 482212 0 0 0 0 520119 0 0 0 0 0 0 0 0 0 0 -(Acetyl)SNVIVKENESLDSALRR MGYG000000187_00800;MGYG000002528_02821;MGYG000000193_00756;MGYG000000078_01046;MGYG000001319_00312;MGYG000003366_01669;MGYG000001543_03644 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 0.8571428571428571 203691|Spirochaetes 0.8571428571428571 L 0.8571428571428571 PFAM Integrase core domain 0.8571428571428571 - 0.8571428571428571 - 1.0 - 1.0 ko:K07497 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 1.0 - 1.0 ko00000 0.8571428571428571 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.8571428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1704678 0 0 0 0 1322091 0 0 0 0 1255997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245923 0 0 0 0 201508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418715 0 0 0 0 0 0 0 0 0 268021 0 0 0 0 0 0 0 0 0 0 -(Acetyl)SVELFDVYEGK MGYG000001364_02003;MGYG000001787_00862;MGYG000003693_02480 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,2FNBF@200643|Bacteroidia,4AM0P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Psort location Cytoplasmic, score 1.0 pheT 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 1.0 6.1.1.20 1.0 ko:K01890 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 B3_4,B5,FDX-ACB,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 966621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1861161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)SWAAEHVVGVAK MGYG000000133_01999 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 560925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)TAVENAAVSQEELDAK MGYG000002469_00869;MGYG000001292_01825 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 Pyruvate formate lyase-like 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bac_luciferase,Fer4_12,Gly_radical,PFL-like,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 223790 0 0 0 283395 0 0 170266 401062 0 0 256097 0 0 0 0 0 0 0 477737 0 0 0 0 0 0 0 0 374356 0 0 0 0 381833 398932 0 0 0 848652 0 0 757873 968956 568306 1193032 975809 692165 834139 0 615058 2340823 780856 0 749203 454452 0 0 1075568 0 347387 0 1247572 0 1046485 928721 0 1447405 860505 1212590 874531 0 837282 872836 779990 752546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287933 0 0 0 380313 0 0 0 0 0 0 0 0 0 465138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)TDTTVEAPATPR MGYG000003683_01126;MGYG000003452_00876;MGYG000002395_00362;MGYG000001490_00332;MGYG000000756_00956;MGYG000002469_01757;MGYG000001292_02350;MGYG000000300_01074;MGYG000003383_00183 phylum d__Bacteria|p__Actinobacteriota 1.0 COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CZCA@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits 1.0 rplE 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02931 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L5,Ribosomal_L5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390180 0 0 0 0 0 656174 0 383377 0 354212 0 0 0 0 0 0 0 0 0 0 0 0 556168 0 0 0 0 824454 0 0 0 0 0 0 0 0 0 703082 0 2199390 0 0 0 500919 661869 942481 0 476714 0 1496447 0 0 0 0 0 0 0 0 553076 0 407559 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252433 0 0 0 0 0 227427 381848 572084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)TNVPADQVDEVLMGC(Carbamidomethyl)VIQAGLGQNVAR MGYG000000262_02231;MGYG000000077_02464 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 508471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 301486 0 490411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632592 1602609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877111 0 1357668 0 0 0 0 0 0 0 0 0 0 930061 0 0 0 0 0 0 0 0 0 259551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251810 0 0 0 0 0 0 0 0 0 0 274803 0 0 0 -(Acetyl)VAGNSATDFENIDKAPEER MGYG000000133_02991;MGYG000001141_02439;MGYG000002286_02469 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1966287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)VAGNSATDFENIDKAPEERER MGYG000000133_02991 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1530718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)VAGNTATDFANIDKAPEER MGYG000000216_02406;MGYG000002492_00344;MGYG000003013_00349;MGYG000002670_00364 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1645030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1315848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1176894 0 0 0 730009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550554 0 0 0 0 0 656457 0 0 0 0 0 0 0 0 659068 0 147303 0 426531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 561733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132492 0 0 0 0 0 0 0 0 157528 0 423428 0 195931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290773 0 0 0 0 0 464930 0 0 0 0 0 0 0 0 0 0 119726 0 -(Acetyl)VAGNTATDFANIDKAPEERER MGYG000000216_02406;MGYG000002492_00344;MGYG000003013_00349;MGYG000002670_00364 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)VSGNAEVAFDNIDKAPEER MGYG000004558_00415 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__|m__MGYG000004558 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,27I75@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2961181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)VTMKNTLGGK MGYG000001300_02837 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2423788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl)VVQHNLTAMNANR MGYG000004271_01770;MGYG000000153_01160;MGYG000000271_01499;MGYG000000404_00502;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 367991 0 272381 919621 0 0 521304 452479 370696 586736 0 427589 0 433237 410596 0 696155 0 0 402380 636041 0 0 323482 550983 516848 699506 0 0 574561 0 0 265640 543984 323249 476675 575133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 844244 0 0 0 763561 561155 0 0 350768 0 865428 815533 0 438810 0 0 459291 467589 0 0 0 852779 1035578 590543 0 0 290554 0 0 0 677198 796013 678430 918048 0 1476981 0 868841 644091 0 1098265 1164108 1050347 1730622 1612913 0 1156658 0 1345640 1571420 736800 1359148 0 0 1532958 1360127 744248 0 1475937 2074776 1840622 1182163 0 0 1947639 0 0 917788 1866582 1804981 1761111 2051083 1007187 -(Acetyl)YALADTVSAGEDSITVDGK MGYG000000280_02459;MGYG000004140_01100;MGYG000003335_00316;MGYG000000164_00800;MGYG000002857_01020;MGYG000000140_01181 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 0.3333333333333333 186801|Clostridia 1.0 G 0.8333333333333334 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1543874 0 0 0 0 0 0 1407121 994058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1806028 0 0 0 0 0 0 0 503495 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl_2H(3))ADLNNENLEALEK MGYG000000031_02020;MGYG000003869_00786;MGYG000000118_02883;MGYG000000212_02552;MGYG000000140_00392;MGYG000000184_03011;MGYG000000133_00802;MGYG000004733_02867;MGYG000000142_02498;MGYG000000002_01091;MGYG000000142_00761;MGYG000001698_00102;MGYG000001689_00148;MGYG000000171_02356;MGYG000001338_00681;MGYG000000031_00146;MGYG000004735_00336;MGYG000000119_00545;MGYG000000171_00584;MGYG000001698_02021;MGYG000000002_02249;MGYG000000212_01928 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae 0.7272727272727273 186801|Clostridia 1.0 H 0.9545454545454546 Belongs to the formate--tetrahydrofolate ligase family 0.8636363636363636 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 617421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 590868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl_2H(3))AVIAYEPVWAIGTGK MGYG000002506_03615 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,3WZWR@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iJN746.PP_4715 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Acetyl_2H(3))LEHTVANLDNVAENTQSAESR MGYG000004271_01770 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 770829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331570 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Amidine)ACVDSGWISADHQVGQTGK MGYG000002794_01438 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp003487665|m__MGYG000002794 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,2N6VH@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3055178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Amidine)ATELVQALK MGYG000002492_01475;MGYG000000018_00274;MGYG000000146_00169;MGYG000000031_02583;MGYG000000404_00576;MGYG000004271_01073;MGYG000000271_00472;MGYG000000142_00943;MGYG000000562_00488;MGYG000000187_00852 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia 0.5 186801|Clostridia 1.0 C 1.0 carboxylase 0.5 oadA 0.8 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Amidine)AVTDAGWMTADHQVGQTGK MGYG000002040_01719;MGYG000002619_02235;MGYG000002223_00611;MGYG000001255_01110;MGYG000001300_00291;MGYG000002610_00221;MGYG000003166_01338;MGYG000000195_01569;MGYG000003291_01730;MGYG000002651_00003;MGYG000000022_01320;MGYG000002274_00049 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1612588 0 0 0 0 0 0 0 0 0 1147756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1742257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Amidine)CVNMVADLWHAPAPK MGYG000002506_00791;MGYG000002323_02099;MGYG000002506_03156;MGYG000002323_00193;MGYG000002507_00543 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,1RNSQ@1236|Gammaproteobacteria,3XMMA@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria 1.0 gadB 1.0 GO:0003674,GO:0003824,GO:0004351,GO:0006873,GO:0006885,GO:0008150,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019725,GO:0030003,GO:0030004,GO:0030641,GO:0042592,GO:0045852,GO:0048878,GO:0050801,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 1.0 4.1.1.15 1.0 ko:K01580 1.0 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 1.0 M00027 1.0 R00261,R00489,R01682,R02466 1.0 RC00299 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECUMN_1333.ECUMN_1747,iUTI89_1310.UTI89_C1707,ic_1306.c1922 1.0 Pyridoxal_deC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate decarboxylase. L-glutamate 1-carboxy-lyase. The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate. H(+) + L-glutamate = 4-aminobutanoate + CO2. 1.0 1.0 1.0 1.0 GABAergic synapse;Type I diabetes mellitus;Taurine and hypotaurine metabolism;Butanoate metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Quorum sensing;beta-Alanine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 12936015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15317769 0 0 0 0 0 0 0 0 0 0 0 0 23293937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Amidine)EGVDVSITGNSTNPTR MGYG000000013_02686;MGYG000002854_01085;MGYG000004735_00009;MGYG000002802_02025;MGYG000003821_01383;MGYG000000205_02543;MGYG000004762_01356;MGYG000002582_01129;MGYG000002159_02251;MGYG000000233_02118;MGYG000004797_02907;MGYG000000140_00469;MGYG000001346_01121;MGYG000000089_00653;MGYG000001871_01775;MGYG000004733_02764;MGYG000004276_01664;MGYG000000242_02797;MGYG000000273_02192;MGYG000004482_01421;MGYG000003221_02162;MGYG000004604_01207;MGYG000000133_00506;MGYG000000127_05084;MGYG000004699_02799;MGYG000001303_02421;MGYG000001698_03439;MGYG000002528_00119;MGYG000002275_01873;MGYG000000032_06095;MGYG000000036_01924;MGYG000001604_01691;MGYG000004464_00921;MGYG000004140_00114;MGYG000000029_00187;MGYG000001378_03489;MGYG000001615_01983;MGYG000002213_00389;MGYG000000045_01847;MGYG000002281_03938;MGYG000000080_01714;MGYG000000268_00554;MGYG000000433_01203;MGYG000003446_01092;MGYG000003872_00869;MGYG000000223_01510;MGYG000000031_02290;MGYG000000118_02684;MGYG000000028_01055;MGYG000001027_01414;MGYG000000142_02731;MGYG000002974_01622;MGYG000000038_01050;MGYG000000347_00819;MGYG000000263_01515;MGYG000001606_02183;MGYG000004824_01069;MGYG000002455_00321;MGYG000001797_00319;MGYG000002194_01220;MGYG000002444_01680;MGYG000000269_00015;MGYG000002985_01044;MGYG000000781_01514;MGYG000001400_01185;MGYG000004822_01055;MGYG000000212_00326;MGYG000001688_03060;MGYG000000198_05683;MGYG000002025_00960;MGYG000001560_01190;MGYG000000042_01753;MGYG000000196_00899;MGYG000001881_00612;MGYG000001496_01287;MGYG000001423_03082;MGYG000003012_02646;MGYG000002880_00963;MGYG000002148_02635;MGYG000000301_00647;MGYG000003589_01350;MGYG000003922_03053;MGYG000003693_01584;MGYG000000179_04738;MGYG000000378_01853;MGYG000002438_03055;MGYG000001697_00682;MGYG000002530_01285;MGYG000003241_01405;MGYG000000312_02568;MGYG000004185_01308;MGYG000001599_00424;MGYG000003457_01216;MGYG000003819_00577;MGYG000000374_01026;MGYG000001237_02019;MGYG000000989_03267;MGYG000001707_00757;MGYG000001618_01635;MGYG000004869_01776;MGYG000002478_02896;MGYG000001785_00655 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.3235294117647059 186801|Clostridia 0.6470588235294118 S 1.0 Psort location Cytoplasmic, score 8.87 0.37254901960784315 - 0.9117647058823529 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 665200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Amidine)SNLDNISENTSSAESR MGYG000001186_01647;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1337692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Amidine)TAPAPAK MGYG000003926_00723 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Rikenella|s__Rikenella microfusus|m__MGYG000003926 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,22UXN@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8036084 -(Amidine)TGANTANEALGNLYIK MGYG000001789_01122;MGYG000001306_03308 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2065754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Amidine)TVDGPSM(Oxidation)KDWR MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003697_01698;MGYG000003457_01802;MGYG000000074_00883;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002834_00628;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000001562_00044;MGYG000004464_00783;MGYG000000254_01186;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000002281_04045;MGYG000000043_01774;MGYG000003363_01174;MGYG000004658_00366;MGYG000004822_01148;MGYG000000044_01948;MGYG000004479_00217;MGYG000000815_03106;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000000412_01371;MGYG000001302.1_00095;MGYG000003252_01337;MGYG000003202_00946;MGYG000003681_00790;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000001661_02632;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000002293_01263;MGYG000003155_00741;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000003908_00471;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.47368421052631576 976|Bacteroidetes 0.9649122807017544 G 0.5087719298245614 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.9473684210526315 gap 0.9824561403508771 - 1.0 1.2.1.12 0.9824561403508771 ko:K00134 0.9824561403508771 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9824561403508771 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9824561403508771 R01061 0.9824561403508771 RC00149 0.9824561403508771 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9824561403508771 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 0.9824561403508771 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9824561403508771 0.9824561403508771 0.9824561403508771 0.9824561403508771 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9824561403508771 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Ammonia-loss)TQEALGMVETR MGYG000000142_01601;MGYG000000301_01353;MGYG000000212_01002;MGYG000001338_00128;MGYG000003012_02044;MGYG000003821_00240;MGYG000004733_01675;MGYG000000216_00449 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Arg)DNELIVGALSVKPR MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2328747 917260 0 0 0 0 0 0 0 1253953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2173080 0 0 0 0 0 -(Arg)DYDVFVGK MGYG000000196_00547;MGYG000000701_00629;MGYG000001378_02385;MGYG000000355_01785;MGYG000002418_01004;MGYG000001306_01408;MGYG000002455_03377;MGYG000001313_02488;MGYG000004622_00252;MGYG000003374_01777;MGYG000000696_00589;MGYG000003681_00897;MGYG000000707_00011;MGYG000002293_00147;MGYG000003697_01824;MGYG000002080_02027;MGYG000002478_02960;MGYG000004885_00524;MGYG000004748_00571;MGYG000004757_01533;MGYG000003312_01455;MGYG000001489_02408;MGYG000004629_01633;MGYG000002281_02540;MGYG000004456_02407;MGYG000000243_01228;MGYG000001056_02440;MGYG000003460_01250;MGYG000001630_00344;MGYG000001750_01904;MGYG000002438_01919;MGYG000001346_01043;MGYG000002218_00698;MGYG000000174_02850;MGYG000000354_00668;MGYG000004495_00381;MGYG000001920_01523;MGYG000003353_01151;MGYG000001783_01031;MGYG000000044_01026;MGYG000001789_00306;MGYG000003362_00812;MGYG000003693_01627;MGYG000000222_02598 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 0.4090909090909091 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3167346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Arg)EEAEEIKK MGYG000000187_02023 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,25WHU@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1197641 0 0 -(Arg)GIEDALQEAYPDWAVR MGYG000000133_00237;MGYG000000301_01546 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 1.0 186801|Clostridia 1.0 M 1.0 Cobalt chelatase (CbiK) 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 74713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1187306 0 0 0 0 0 0 0 0 0 0 0 2160632 0 0 0 0 0 0 957606 0 0 0 0 0 0 0 0 0 0 682486 0 0 0 0 0 0 0 112692 0 0 0 0 0 0 0 0 0 0 0 0 0 172522 0 0 0 0 88768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388074 0 0 0 0 0 456870 0 0 0 0 0 0 905630 0 0 0 0 367585 0 483128 0 0 0 0 316425 0 0 0 0 0 0 0 0 0 0 730015 0 -(Arg)TQEALGMVETR MGYG000000142_01601;MGYG000000301_01353;MGYG000000212_01002;MGYG000001338_00128;MGYG000003012_02044;MGYG000003821_00240;MGYG000004733_01675;MGYG000000216_00449 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530384 0 408944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1606219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1154324 0 1203031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Arg)VAGNTATDFENIDKAPEER MGYG000002517_00205;MGYG000003425_03741;MGYG000000018_00453;MGYG000002212_00196;MGYG000001602_02247;MGYG000000501_01307;MGYG000001698_04050;MGYG000001619_01314 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 0.375 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Arg)VINLDKESEPDIYNAIR MGYG000001306_02577;MGYG000000451_00938;MGYG000001657_02023;MGYG000001733_01436;MGYG000001666_00909;MGYG000001763_01029;MGYG000001164_02313;MGYG000000622_01660;MGYG000003022_01459;MGYG000001531_02004;MGYG000001643_01060;MGYG000004740_01746;MGYG000002445_00666;MGYG000000258_01582;MGYG000000133_00275;MGYG000001065_01729;MGYG000001315_01422;MGYG000000251_02509;MGYG000004721_01708;MGYG000002721_02375 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,3WGXZ@541000|Ruminococcaceae 0.3 186801|Clostridia 0.65 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 0.7 4.1.1.49 0.95 ko:K01610 0.95 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 0.95 M00003,M00170 0.95 R00341 0.95 RC00002,RC02741 0.95 ko00000,ko00001,ko00002,ko01000 0.95 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 0.95 0.95 0.95 0.95 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.95 none 1.0 0 0 0 77989 0 0 0 0 88411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122992 0 0 70447 0 0 0 77174 0 0 136127 0 0 121263 49973 0 268717 0 0 225087 0 0 0 144308 0 0 0 0 0 0 0 202043 0 0 0 0 0 0 0 0 0 77051 0 0 0 0 0 0 0 0 96496 129854 95501 66111 0 0 0 192324 135749 167233 0 78386 0 0 0 0 0 0 0 79137 0 242002 0 0 0 141633 86219 197384 0 80362 0 0 0 0 82054 0 0 0 134217 0 0 0 0 0 0 0 0 0 0 248921 0 0 0 0 0 0 0 0 0 169328 0 0 0 0 0 93777 0 0 0 0 0 0 93484 0 0 0 169607 567045 690022 580393 719573 0 0 1075939 540256 576784 0 750956 0 0 0 753201 0 0 0 621102 0 916542 0 0 0 585803 423320 873409 0 948763 0 0 0 954813 794424 0 459893 214895 472223 -(Arg)VSQTGATQNAMTVSWTPENK MGYG000004735_01325 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG5492@1|root,COG5492@2|Bacteria,1UINF@1239|Firmicutes,25EP2@186801|Clostridia,4C1TK@830|Butyrivibrio 1.0 186801|Clostridia 1.0 N 1.0 Fibronectin type 3 domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fn3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1268701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(BITC)DNELIVGALSVKPR MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Benzoyl)TAEGALNETHSILQR MGYG000000154_02141;MGYG000003142_01387;MGYG000003142_01386 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,36ED6@31979|Clostridiaceae 0.6666666666666666 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 fliC 0.6666666666666666 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_IN,Flagellin_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 142714 0 0 0 0 0 0 0 0 0 165141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 672500 0 0 667915 0 0 0 0 0 0 0 0 0 1279848 1173337 0 0 0 0 0 0 0 0 0 0 637252 0 0 0 657191 0 0 0 0 1013196 0 1380391 0 579019 0 0 0 0 0 0 0 0 0 0 0 0 108235 759747 0 0 0 0 0 0 0 0 0 0 137085 0 0 0 393398 0 0 0 0 0 0 108844 0 -(Benzoyl)TCVAFNVTSKEQVIINTWYGGEMK MGYG000003697_01524 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,4AMYK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Biotin)ENGIGIVDIVENR MGYG000001338_00631;MGYG000000142_01654;MGYG000002528_00148;MGYG000000216_00388 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3XYUF@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 8.87 1.0 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Fluid shear stress and atherosclerosis;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Biotin)EPGALGEPLYLDVVAALK MGYG000001338_02036 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Biotin)KYVSERGK MGYG000000133_02916;MGYG000000184_02507 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,3Y0A3@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit 1.0 rpsR 1.0 - 1.0 - 1.0 ko:K02963 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S18 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Biotin)LEAMKMQNEIMAPADGTISDVR MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Biotin)NDLVPVDYMAYMLK MGYG000001546_00360 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes provencensis|m__MGYG000001546 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,22V16@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4827188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7345106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Biotin)QEGGYTYIFDLNR MGYG000002478_01528 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Biotin)SAVYSDLAETILPQLR MGYG000002438_01767;MGYG000000138_03130 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG3063@1|root,COG3063@2|Bacteria,4PKG6@976|Bacteroidetes,2G3G2@200643|Bacteroidia,2322F@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 NU 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 711043 42589709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14067380 0 0 0 0 0 0 21959821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Brij35)SFDSIDNAPEEKER MGYG000000042_01421;MGYG000004756_01173;MGYG000000196_03974;MGYG000002905_00001;MGYG000000138_00665;MGYG000001661_02666;MGYG000000053_00908;MGYG000004006_00433;MGYG000002762_01733;MGYG000000074_01773;MGYG000001789_00154;MGYG000000273_00431;MGYG000000054_03933;MGYG000000236_01807;MGYG000003701_03123;MGYG000000098_02017;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000001503_00139;MGYG000002281_02290;MGYG000004474_01617;MGYG000003546_00955;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000003446_00658;MGYG000001552_00984;MGYG000001346_01533;MGYG000000243_01988;MGYG000000013_02251;MGYG000001562_01075;MGYG000000348_00283;MGYG000003279_00951;MGYG000000414_00662;MGYG000001655_02933;MGYG000000044_01721;MGYG000002418_00753;MGYG000000117_01463;MGYG000000168_03211 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6142284 0 0 0 7453476 5355460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 349509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1872262 0 0 0 572219 1581238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7781236 0 0 0 3460870 4774993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 849938 0 0 0 1521005 1322341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Brij58)RAALHEFNPMMGHR MGYG000002528_02478 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)AANPTPDEPFVLGC(Carbamidomethyl)PTGSSPLGMYK MGYG000000098_01118 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides bouchesdurhonensis|m__MGYG000000098 1.0 COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,4AKMP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 240776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1750294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1682271 -(C+12)DKPFLMPIEDVMTISGR MGYG000001300_00280 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11073721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)EPFSALAFK MGYG000002528_01099;MGYG000001756_00184;MGYG000000142_00172;MGYG000000251_00063;MGYG000004769_00436;MGYG000000412_01545;MGYG000002494_01997;MGYG000000233_00808;MGYG000000200_01983;MGYG000001688_04230;MGYG000002421_00703;MGYG000000377_01099;MGYG000003022_00736;MGYG000000038_00759;MGYG000002492_00343;MGYG000001507_06244;MGYG000000269_00802;MGYG000001315_01206;MGYG000000173_00404;MGYG000004642_00845;MGYG000000371_01542;MGYG000000127_03983;MGYG000000206_00900 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.34782608695652173 186801|Clostridia 0.6956521739130435 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 0.9130434782608695 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113797 0 0 0 0 0 0 0 0 0 0 0 0 136852 0 0 0 782104 0 0 819384 0 1118421 1000545 746521 0 1182095 0 1242987 0 1114727 0 0 0 0 0 935329 0 625067 0 272991 0 649524 0 0 0 0 0 0 0 0 534394 0 980553 0 0 0 0 0 0 286122 0 0 0 227150 0 0 0 403870 0 0 0 0 0 139292 0 367863 0 0 0 350239 0 0 0 0 0 0 0 0 372853 0 0 0 0 0 0 0 0 0 0 224489 0 157007 0 146066 0 236474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281660 0 0 0 0 154928 0 0 266073 210737 0 0 0 0 0 0 0 0 0 0 0 0 0 424895 0 228537 0 163420 0 0 0 0 0 0 0 0 553777 0 218934 0 -(C+12)FTQAGSEVSALIGR MGYG000001780_01558;MGYG000000213_03735;MGYG000000236_04466;MGYG000002040_00953;MGYG000002033_02017;MGYG000001423_01292;MGYG000000146_02637;MGYG000002478_03332;MGYG000002042_00234;MGYG000000184_02765;MGYG000001619_01979;MGYG000000133_01065;MGYG000002517_03146;MGYG000003366_00975 domain d__Bacteria 1.0 COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,2FP0J@200643|Bacteroidia,4AKDD@815|Bacteroidaceae 0.21428571428571427 186801|Clostridia 0.7142857142857143 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 0.6428571428571429 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)FTQAGSEVSALLGR MGYG000000427_01448;MGYG000000028_00163;MGYG000001469_01126;MGYG000000213_03735;MGYG000003539_00081;MGYG000001306_00933;MGYG000000562_01724;MGYG000000201_01407;MGYG000000701_01560;MGYG000001552_03919;MGYG000002293_00144;MGYG000004039_01687;MGYG000002689_00805;MGYG000000312_01414;MGYG000004785_01194;MGYG000003498_00140;MGYG000001346_00388;MGYG000001635_01643;MGYG000003693_01490;MGYG000002312_02770;MGYG000000281_00461;MGYG000004679_00453;MGYG000000223_02026;MGYG000001027_00128;MGYG000004893_01690;MGYG000001558_00980;MGYG000000707_01777;MGYG000003695_02077;MGYG000002756_03006;MGYG000001697_01966;MGYG000004732_02133;MGYG000002563_01157;MGYG000004735_02328;MGYG000002148_00268;MGYG000003335_00448;MGYG000000187_01497;MGYG000004479_02289;MGYG000001315_02894;MGYG000002149_01760;MGYG000000953_00406;MGYG000004729_01517;MGYG000000196_02094;MGYG000001461_00699;MGYG000004691_00177;MGYG000004899_02408;MGYG000002140_01025;MGYG000000387_00075;MGYG000003694_02221;MGYG000002996_00349;MGYG000000251_00949;MGYG000002072_00153;MGYG000004558_00486;MGYG000000236_04466;MGYG000002545_01157;MGYG000001689_03424;MGYG000004019_00309;MGYG000001423_01292;MGYG000003702_00794;MGYG000004891_02692;MGYG000000098_02154;MGYG000003381_01169;MGYG000000184_02765;MGYG000003201_00717;MGYG000001374_01252;MGYG000000415_01739;MGYG000000138_00270;MGYG000000133_01065;MGYG000001370_01600;MGYG000000356_01025;MGYG000000323_02070;MGYG000001637_00761;MGYG000003367_02409;MGYG000004317_01545;MGYG000002286_00500;MGYG000000200_02339;MGYG000002641_02172;MGYG000004359_00873;MGYG000000690_01023;MGYG000000280_00975;MGYG000000187_00876;MGYG000003221_00065;MGYG000000515_02194;MGYG000001688_00407;MGYG000002478_03332;MGYG000004767_00409;MGYG000000029_01373;MGYG000001460_03542;MGYG000001007_00074;MGYG000003147_00100;MGYG000003984_00638;MGYG000002455_03102;MGYG000000036_00372;MGYG000001787_02529;MGYG000000215_02164;MGYG000000144_02454;MGYG000000174_01227;MGYG000000963_00198;MGYG000004703_00701;MGYG000001835_01143;MGYG000000287_00695;MGYG000000013_03756;MGYG000002360_00370;MGYG000002721_00656;MGYG000003291_01613;MGYG000004884_01676;MGYG000001655_01482;MGYG000003353_00328;MGYG000002245_01405;MGYG000000022_01420;MGYG000001531_01376;MGYG000000974_00540;MGYG000001447_00122;MGYG000000249_02082;MGYG000003921_00620;MGYG000004548_00278;MGYG000000484_00117;MGYG000002596_00246;MGYG000002517_03146;MGYG000003521_01445;MGYG000004828_00155;MGYG000001770_02068;MGYG000000170_00283;MGYG000000077_01276;MGYG000000417_01692;MGYG000004748_02718;MGYG000000204_01994;MGYG000003899_00596;MGYG000002042_00234;MGYG000002274_00866;MGYG000000175_03681;MGYG000000357_00511;MGYG000001420_00622;MGYG000002560_03936;MGYG000004789_00517;MGYG000003460_00897;MGYG000001338_03253;MGYG000002549_01699;MGYG000000146_02637;MGYG000003822_01520;MGYG000004797_02202;MGYG000002492_00116;MGYG000000164_01253;MGYG000001319_01872;MGYG000000042_02500;MGYG000000356_01862;MGYG000000318_00912;MGYG000002370_03742;MGYG000000105_00454;MGYG000000212_01192;MGYG000002421_01632;MGYG000000171_01102;MGYG000000224_02822;MGYG000003219_00228;MGYG000002218_01404;MGYG000003908_02773;MGYG000000076_02190;MGYG000003363_01154;MGYG000002052_00992;MGYG000002651_01644;MGYG000003362_00510;MGYG000002780_01575;MGYG000000226_00744;MGYG000004757_00198;MGYG000001300_02368;MGYG000001337_02728;MGYG000001400_02546;MGYG000003202_00654;MGYG000003701_04546;MGYG000000195_00674;MGYG000004545_00253;MGYG000000242_03210;MGYG000003500_00568;MGYG000002298_03479;MGYG000000044_01379;MGYG000000222_00569;MGYG000002492_02635;MGYG000000152_02848;MGYG000002552_02014;MGYG000000268_02191;MGYG000002528_01017;MGYG000002216_00439;MGYG000001780_01558;MGYG000001378_01045;MGYG000000278_03709;MGYG000004022_00852;MGYG000001065_01646;MGYG000000252_00908;MGYG000002485_02059;MGYG000000154_01956;MGYG000001313_01535;MGYG000001429_00858;MGYG000002131_00369;MGYG000004526_00330;MGYG000002997_01322;MGYG000001543_00548;MGYG000000867_00145;MGYG000002171_00087;MGYG000000245_03609;MGYG000000039_00037;MGYG000000280_00335;MGYG000002040_00953;MGYG000001489_01224;MGYG000002033_02017;MGYG000000119_02239;MGYG000002203_00701;MGYG000000243_00496;MGYG000003697_01827;MGYG000003812_00631;MGYG000004853_00155;MGYG000002275_01953;MGYG000002610_02017;MGYG000004271_01938;MGYG000001793_01261;MGYG000002772_01182;MGYG000003937_00311;MGYG000001345_02851;MGYG000001785_00789;MGYG000003366_00975;MGYG000002272_00435;MGYG000000262_00505;MGYG000003922_02492;MGYG000004431_00647;MGYG000001056_00141;MGYG000001777_00207;MGYG000003351_01481;MGYG000001186_01383;MGYG000000136_01559;MGYG000001619_01979;MGYG000003411_00809;MGYG000002470_03481;MGYG000002036_00388 domain d__Bacteria 1.0 COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,2FP0J@200643|Bacteroidia,4AKDD@815|Bacteroidaceae 0.1645021645021645 186801|Clostridia 0.5584415584415584 C 0.9783549783549783 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 0.9956709956709957 atpD 0.9956709956709957 - 0.5454545454545454 3.6.3.14 0.9826839826839827 ko:K02112 0.9826839826839827 ko00190,ko00195,ko01100,map00190,map00195,map01100 0.9826839826839827 M00157 0.9826839826839827 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 0.9826839826839827 3.A.2.1 0.9826839826839827 - 1.0 - 0.9653679653679653 ATP-synt_ab,ATP-synt_ab_N 0.9956709956709957 - 1.0 - 1.0 - 1.0 GT58 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 0.9826839826839827 0.9826839826839827 0.9826839826839827 0.9826839826839827 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 0.9826839826839827 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 687304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)IFFAAASAADKMR MGYG000000198_05065;MGYG000000179_02579 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,2686V@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)INNLGFIETPYR MGYG000004830_01656;MGYG000000348_00276 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-485 1.0 COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,2FMDI@200643|Bacteroidia,22X4R@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3624927 0 0 0 0 -(C+12)LTTEQMLPIVDK MGYG000000212_00765 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 829435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)MVEAGILDPVKVTR MGYG000000404_00409 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA11774|s__UBA11774 sp003507655|m__MGYG000000404 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)QTVVFDTDEGPR MGYG000000312_01321 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eisenbergiella|s__Eisenbergiella sp900539715|m__MGYG000000312 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,4BW0W@830|Butyrivibrio 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)SSLGAVQNR MGYG000002506_01312;MGYG000000489_01309;MGYG000002670_01665;MGYG000002670_01663;MGYG000002492_03078;MGYG000001470_04044 domain d__Bacteria 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6666666666666666 186801|Clostridia 0.6666666666666666 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 0.6666666666666666 - 0.6666666666666666 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 329885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3349796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)TATAEQAQEIHAFIR MGYG000004899_00852;MGYG000000243_02890;MGYG000002478_00492 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0149@1|root,COG2259@1|root,COG0149@2|Bacteria,COG2259@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia,4AVCD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 DoxX,MauE,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1625018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 764583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1471624 0 0 0 0 0 0 1880646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)TLDYDLIITGR MGYG000004285_02086;MGYG000004642_01566 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36EI7@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 304394 0 408281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306882 0 279022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 678868 0 754580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)VGYVMWPLR MGYG000002279_01699;MGYG000002992_02039 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,27UV0@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) 1.0 gltX 1.0 - 1.0 6.1.1.17,6.1.1.24 1.0 ko:K01885,ko:K09698 1.0 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 1.0 M00121,M00359,M00360 1.0 R03651,R05578 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 1.0 - 1.0 - 1.0 - 1.0 tRNA-synt_1c 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate--tRNA ligase. | glutamate--tRNA(Gln) ligase. glutamyl-tRNA synthetase. | nondiscriminating glutamyl-tRNA synthetase. When this enzyme acts on tRNA(Glu), it catalyzes the same reaction as EC 6.1.1.17.-!-It has, however, diminished discrimination, so that it can also form glutamate-tRNA(Gln).-!-This relaxation of specificity has been found to result from the absence of a loop in the tRNA that specifically recognizes the third position of the anticodon.-!-This accounts for the ability of this enzyme in, for example, Bacillus subtilis, to recognize both tRNA1(Gln) (UUG anticodon) and tRNA(Glu) (UUC anticodon) but not tRNA2(Gln) (CUG anticodon).-!-The ability of this enzyme to recognize both tRNA(Glu) and one of the tRNA(Gln) isoacceptors derives from their sharing a major identity element, a hypermodified derivative of U34 (5-methylaminomethyl-2- thiouridine).-!-The glutamyl-tRNA(Gln) is not used in protein synthesis until it is converted by EC 6.3.5.7 into glutaminyl-tRNA(Gln). ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu). | ATP + L-glutamate + tRNA(Glx) = AMP + diphosphate + L-glutamyl-tRNA(Glx). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis;Metabolic pathways;Porphyrin metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 141071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 301226 0 0 0 0 407148 0 0 135311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1338881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1087333 0 0 0 0 1295071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204915 0 0 0 0 204460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)VQSDSSDDTKEK MGYG000000198_05929 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,21ZAM@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 5709476 0 0 0 0 1613057 0 0 0 3502592 0 0 0 0 3923359 0 3645316 0 0 0 0 2195139 0 3188264 0 5292322 0 0 0 3714586 0 0 0 0 0 0 4958519 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147037 0 0 0 0 49137 0 0 0 203119 0 0 0 0 240267 0 48207 0 0 0 0 53933 0 93297 0 152200 0 0 0 56266 0 0 0 0 0 0 166537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)WILDNVEGAR MGYG000000157_02893;MGYG000003142_01159;MGYG000003425_03258;MGYG000000268_00688;MGYG000001698_01656;MGYG000003381_02295;MGYG000001326_01728;MGYG000001619_01501;MGYG000000142_00490;MGYG000000164_01754;MGYG000001338_01881;MGYG000002517_00259;MGYG000004785_01998;MGYG000002517_00523;MGYG000001508_01328;MGYG000001470_01135;MGYG000001464_01751;MGYG000000263_01173 domain d__Bacteria 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 0.2222222222222222 186801|Clostridia 0.7777777777777778 C 0.5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 0.7222222222222222 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5560579 0 0 0 -(C+12)WILDNVEGVR MGYG000000179_02171;MGYG000000198_04024;MGYG000000087_01966 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 461529 1350017 0 0 0 0 0 0 1401625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309527 0 0 0 0 0 0 127909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1357285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)WLLDNVEGAR MGYG000003142_01159;MGYG000000157_02893;MGYG000000337_00220;MGYG000002807_00504;MGYG000003425_03258;MGYG000000268_00688;MGYG000001698_01656;MGYG000001619_01501;MGYG000000142_00490;MGYG000000389_02030;MGYG000000164_01754;MGYG000000334_01513;MGYG000000083_02973;MGYG000001627_01644;MGYG000001338_01881;MGYG000002517_00259;MGYG000002517_00523;MGYG000001508_01328;MGYG000004431_01182;MGYG000001470_01135;MGYG000001464_01751 domain d__Bacteria 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 0.23809523809523808 186801|Clostridia 0.7619047619047619 C 0.5238095238095238 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 0.9523809523809523 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 0.9523809523809523 FGGY_C,FGGY_N,MazG 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 322764 0 315422 0 2357008 1081792 236040 273646 0 95439 0 0 0 2717254 0 2663366 398711 0 585063 625884 2729319 759150 0 313590 0 255261 0 0 0 0 0 0 226639 286658 304727 184475 326760 220157 0 0 108571 0 139866 0 138604 219488 0 99638 0 0 0 75854 0 0 0 0 104259 236423 0 0 0 0 0 112257 0 0 0 0 219372 0 88719 0 230499 99112 0 0 160786 0 0 0 78942 0 220582 276922 0 273164 0 0 0 118939 229382 180467 100607 0 270410 279704 0 141586 0 181767 0 181440 0 0 0 0 155905 0 123992 334312 344235 243253 366664 0 507655 0 240473 0 404336 294051 514983 0 0 351258 0 0 0 1296254 1514248 645817 811762 0 1117380 1596873 1020706 128039 0 0 0 1760539 0 0 0 0 484020 0 491220 1549478 1990940 1855297 0 669116 707456 0 710707 0 646732 1040576 1896387 1309801 0 1998137 0 0 0 257365 2338720 1189438 3000089 0 2370551 2210501 1983397 2049295 0 191994 0 3274428 0 0 0 0 2495137 0 3366766 5696661 0 0 5822232 0 -(C+12)WLLDNVPGAR MGYG000001315_01111;MGYG000004733_00600;MGYG000003152_00994;MGYG000002641_02439;MGYG000000003_00783;MGYG000000038_01493;MGYG000000489_01562;MGYG000001749_00513;MGYG000002312_03080;MGYG000000245_01078;MGYG000003374_00008;MGYG000002926_00484;MGYG000003166_01103;MGYG000001546_02385;MGYG000002274_01022;MGYG000004536_01113;MGYG000002802_02075;MGYG000000195_02804;MGYG000002279_02521;MGYG000000205_00108;MGYG000000252_02425;MGYG000004525_02134;MGYG000004762_00048 domain d__Bacteria 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,27V84@189330|Dorea 0.30434782608695654 186801|Clostridia 0.782608695652174 H 0.43478260869565216 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 0.5652173913043478 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1176119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C+12)WLPIAAAAQLTK MGYG000000301_01129;MGYG000000133_00992 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0510@1|root,COG0510@2|Bacteria,1TQW6@1239|Firmicutes,248A0@186801|Clostridia,36UHB@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 M 1.0 Phosphotransferase enzyme family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 APH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5354316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C8-QAT)DFDDAVEQAVWLEHGNR MGYG000000201_01080;MGYG000001338_00133;MGYG000002772_00609;MGYG000000133_00166;MGYG000004733_01680;MGYG000002298_02774;MGYG000000268_01901;MGYG000000175_02146;MGYG000000142_01606;MGYG000000212_01007;MGYG000002298_00039;MGYG000000249_01486 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,3XZI5@572511|Blautia 0.5833333333333334 186801|Clostridia 1.0 C 1.0 Aldehyde dehydrogenase family 0.8333333333333334 eutE 1.0 - 1.0 1.2.1.10,1.2.1.87 1.0 ko:K00132,ko:K13922 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00228,R01172,R09097 1.0 RC00004,RC00184,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetaldehyde dehydrogenase (acetylating). | propanal dehydrogenase (CoA-propanoylating). aldehyde dehydrogenase (acylating). Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme forms a bifunctional complex with EC 4.1.3.43, with a tight channel connecting the two subunits.-!-Also acts, more slowly, on glycolaldehyde and butanal.-!-In Pseudomonas species the enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.10.-!-NADP(+) can replace NAD(+) with a much slower rate. acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NAD(+) + propanal = H(+) + NADH + propanoyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340289 0 0 0 0 0 0 0 0 0 0 813698 0 581420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762885 0 0 0 0 0 0 0 0 0 0 952806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 935172 0 0 0 0 0 0 0 0 0 0 700242 0 548089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 653037 0 0 0 0 0 0 0 0 0 0 385724 0 795021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1163783 0 0 0 0 0 0 0 0 0 0 261023 0 -(C8-QAT)LAAYGAELVLTEGAK MGYG000002517_02918 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the cysteine synthase cystathionine beta- synthase family 1.0 cysK 1.0 - 1.0 2.5.1.47 1.0 ko:K01738 1.0 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00021 1.0 R00897,R03601,R04859 1.0 RC00020,RC02814,RC02821 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PALP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 cysteine synthase. OAS sulfhydrylase. Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors.-!-Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53.-!-Formerly EC 4.2.99.8. hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine. 1.0 1.0 1.0 1.0 Sulfur metabolism;Carbon metabolism;Metabolic pathways;Cysteine and methionine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(C8-QAT)MSNISAYDQGLNESFQGAFK MGYG000003891_02475 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(CAF)FDFRGVEATFELNDANK MGYG000002494_00458 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,3XN7B@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 UPF0234 protein YajQ 1.0 yajQ 1.0 GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 - 1.0 ko:K09767 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF520 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 512708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 777231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(CAF)IQAGSEVSALLGR MGYG000004769_01910 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4H2IA@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 - 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(CAF)RTAVQQEINQLASEITR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(CAMthiopropanoyl)YAIIATGGK MGYG000002517_01481;MGYG000000077_02303;MGYG000000171_00402;MGYG000000271_00118;MGYG000000028_00974;MGYG000004087_00797;MGYG000001714_01831;MGYG000000179_02644;MGYG000000198_03199;MGYG000001531_02377;MGYG000003684_00524 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,269QB@186813|unclassified Clostridiales 0.36363636363636365 186801|Clostridia 1.0 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 - 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133976 0 0 0 0 0 0 0 0 0 0 0 0 -(CLIP_TRAQ_2)GMSVLEYFIASHGAR MGYG000000215_00573;MGYG000002080_00535 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4860935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(CLIP_TRAQ_2)ITELGIYPAVDPLESTSR MGYG000001315_02894;MGYG000003367_02409;MGYG000000243_00496;MGYG000002478_03332;MGYG000000236_04466;MGYG000000415_01739;MGYG000004748_02718;MGYG000004797_02202;MGYG000003363_01154;MGYG000000044_01379;MGYG000003521_01445 domain d__Bacteria 1.0 COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,2FP0J@200643|Bacteroidia,4AKDD@815|Bacteroidaceae 0.6363636363636364 976|Bacteroidetes 0.9090909090909091 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 - 0.9090909090909091 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(CLIP_TRAQ_3)IAMHTLDGGR MGYG000000076_01275;MGYG000000217_01340;MGYG000004740_00273;MGYG000001615_04301;MGYG000000205_02133;MGYG000000164_00686;MGYG000003074_00587;MGYG000000153_01461;MGYG000001637_02229;MGYG000000255_01556;MGYG000001315_01868;MGYG000001617_02045;MGYG000000489_01025;MGYG000002670_01509;MGYG000002492_00659;MGYG000002528_02667;MGYG000000077_02467;MGYG000000204_00801;MGYG000003694_00879;MGYG000001777_01058;MGYG000002278_01893;MGYG000000312_02425;MGYG000000127_04022;MGYG000001793_01807;MGYG000000280_01471;MGYG000002945_00737;MGYG000000139_01931;MGYG000001564_00904;MGYG000000136_00900;MGYG000000271_02102;MGYG000000404_01797;MGYG000004271_00233;MGYG000000389_02149;MGYG000004039_00586;MGYG000001814_02502;MGYG000004762_01001;MGYG000001186_01721;MGYG000001199_01107;MGYG000000028_00943;MGYG000002517_00542;MGYG000000262_02234;MGYG000003486_02522;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.37209302325581395 186801|Clostridia 1.0 C 0.6976744186046512 acyl-CoA dehydrogenase 0.3953488372093023 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(CLIP_TRAQ_3)VIEFNPALEENNRYVEIMDIVK MGYG000002492_00661 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603538 0 0 0 0 677662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12179258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1642995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AAATAIYGSR MGYG000004748_03723;MGYG000001789_02910;MGYG000001925_00084 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2042534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1162985 0 0 0 0 0 -(Carbamidomethyl)AAAVNIVPNSTGAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AADDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 342686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375111 316750 0 0 667383 0 0 0 466068 160542 332195 365372 0 301807 0 0 0 0 0 0 0 0 0 0 0 0 1140561 0 0 0 0 0 0 0 0 0 0 0 0 315677 0 0 276065 0 0 0 396305 232859 899485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1751417 0 0 0 0 0 0 3526729 0 0 0 0 0 2056657 2726339 0 0 0 0 0 0 0 0 0 0 2273330 1939803 0 0 1712148 0 0 0 2748220 2088357 1799099 2882425 0 829638 0 0 0 0 0 0 722023 0 0 0 0 0 0 312605 0 0 0 0 0 0 0 0 0 0 1095563 459680 0 0 1283294 0 0 0 905318 498841 750079 1653724 0 -(Carbamidomethyl)AAIEEGIVPGGGVAYIR MGYG000004876_02137;MGYG000002478_00380;MGYG000003363_02977;MGYG000002171_01748;MGYG000004763_01826;MGYG000002470_00024;MGYG000000243_00634;MGYG000002455_00111;MGYG000001346_02504;MGYG000002933_01569 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AALEEAGASVELK MGYG000003730_01040 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium vaginale_E|m__MGYG000003730 1.0 COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4D0W2@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2378388 2768829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2691950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AASGNIIPSSTGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)ADDAAGLAISEK MGYG000002934_00200 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Caproiciproducens|s__Caproiciproducens sp900546895|m__MGYG000002934 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 hag 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1531635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AGDDAAGLTISEK MGYG000000356_01643;MGYG000000484_02079;MGYG000000153_01160;MGYG000000389_01367;MGYG000000076_03207;MGYG000001186_01647 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AGIALTDTFVK MGYG000003589_01892;MGYG000002540_02142;MGYG000001783_01519;MGYG000003457_01802;MGYG000002057_00658;MGYG000004006_01717;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000002944_01470;MGYG000001345_01069;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002006_01638;MGYG000001749_01249;MGYG000002455_02200;MGYG000001356_02656;MGYG000004487_00117;MGYG000001546_00360;MGYG000000086_02423;MGYG000004726_03349;MGYG000004638_00838;MGYG000000377_02142;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000003681_00790;MGYG000000003_00712;MGYG000002933_02039;MGYG000004482_00387;MGYG000000196_00479;MGYG000003693_00860;MGYG000001661_02632;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000002867_00573;MGYG000000053_01377;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.43859649122807015 976|Bacteroidetes 0.6666666666666666 C 0.5614035087719298 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7719298245614035 gap 0.9473684210526315 - 1.0 1.2.1.12 0.9649122807017544 ko:K00134 0.9649122807017544 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9649122807017544 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9649122807017544 R01061 0.9649122807017544 RC00149 0.9649122807017544 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9649122807017544 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 0.9649122807017544 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9649122807017544 0.9649122807017544 0.9649122807017544 0.9649122807017544 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9649122807017544 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545358 0 0 0 0 0 0 0 0 0 733097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AGIQLSPR MGYG000000170_00182 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900240235|m__MGYG000000170 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,22V16@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1409206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AGIQQEIR MGYG000000152_00117;MGYG000000141_00660;MGYG000002580_01017;MGYG000000095_00173;MGYG000000501_01598;MGYG000000255_00059;MGYG000004055_00346;MGYG000004431_01868;MGYG000000245_00531;MGYG000000280_00278;MGYG000002445_00245;MGYG000003425_03997;MGYG000002492_01669;MGYG000004414_01258;MGYG000000252_02525;MGYG000002992_00107;MGYG000002417_00179;MGYG000002836_01191;MGYG000002289_01189;MGYG000000187_00800;MGYG000002528_02821;MGYG000004250_00815;MGYG000000515_01072;MGYG000003500_01059;MGYG000001439_01091;MGYG000004785_00784;MGYG000000997_01904;MGYG000000359_00890;MGYG000000274_02713;MGYG000000175_00584;MGYG000002945_00316;MGYG000001619_00224;MGYG000000076_00705;MGYG000000398_02117;MGYG000001637_00450;MGYG000000067_02614;MGYG000004891_00983;MGYG000004799_00190;MGYG000002393_01989;MGYG000004879_00968;MGYG000000242_01546;MGYG000001065_00121;MGYG000004691_01413;MGYG000002304_00585;MGYG000004548_02161;MGYG000002278_00495;MGYG000001954_00183;MGYG000000312_02314;MGYG000001456.1_00409;MGYG000000136_01431;MGYG000000562_00584;MGYG000000204_01228;MGYG000000159_01824;MGYG000002286_00159;MGYG000000909_01150;MGYG000003694_00392;MGYG000004519_00667;MGYG000000193_00756;MGYG000000078_01046;MGYG000000231_00737;MGYG000003366_01669;MGYG000001543_03644;MGYG000001571_02035;MGYG000000087_00069;MGYG000004740_00388;MGYG000001193_00159;MGYG000000229_01952;MGYG000002247_01714;MGYG000002517_01319;MGYG000000325_01546;MGYG000003381_02022;MGYG000004039_02066;MGYG000000145_01503;MGYG000001531_02509;MGYG000000154_00852;MGYG000000278_03375;MGYG000001606_01557;MGYG000002963_01774;MGYG000001814_01719;MGYG000000217_00552;MGYG000001319_00312 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 0.9259259259259259 203691|Spirochaetes 0.9259259259259259 L 0.9259259259259259 PFAM Integrase core domain 0.9259259259259259 - 0.9259259259259259 - 1.0 - 1.0 ko:K07497 0.9259259259259259 - 0.9259259259259259 - 0.9259259259259259 - 1.0 - 1.0 ko00000 0.9259259259259259 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 0.9259259259259259 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9259259259259259 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AGPVILEPIMK MGYG000000358_00904 genome d__Bacteria|p__Elusimicrobiota|c__Elusimicrobia|o__Elusimicrobiales|f__Elusimicrobiaceae|g__UBA1436|s__UBA1436 sp002329395|m__MGYG000000358 1.0 COG0480@1|root,COG0480@2|Bacteria 1.0 2|Bacteria 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AGTTAESLAK MGYG000004271_00231;MGYG000000245_02019;MGYG000000271_02104 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AGVKPEMVDEVK MGYG000004271_00231;MGYG000000489_01023;MGYG000000271_02104;MGYG000000280_01473;MGYG000001637_02269;MGYG000003694_00877 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 3132296 1898042 0 0 0 2858956 0 0 0 1997980 0 0 0 0 2860622 0 0 0 0 0 0 0 0 0 0 3024464 0 0 0 0 0 0 0 0 0 3463999 0 0 0 181822 0 0 0 177804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174488 0 0 0 0 0 0 0 0 0 354597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189173 0 0 0 0 0 0 0 0 0 154991 0 0 0 0 0 0 0 0 0 0 80328 0 -(Carbamidomethyl)AGVTKEDINAAMK MGYG000003694_01737;MGYG000001311_02933;MGYG000001186_01925;MGYG000001065_01088;MGYG000000271_03250;MGYG000004271_00554;MGYG000000404_00344;MGYG000001493_05257;MGYG000002517_01026;MGYG000000179_02084;MGYG000002492_01379;MGYG000000489_00503;MGYG000000198_04065 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6153846153846154 186801|Clostridia 1.0 G 0.6153846153846154 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.6153846153846154 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AKFVTIGER MGYG000004785_01065;MGYG000000142_02501;MGYG000002298_01759;MGYG000000171_00587;MGYG000002286_00195;MGYG000000251_00652;MGYG000000200_00066;MGYG000002312_01594;MGYG000000002_02252;MGYG000000141_00320;MGYG000000252_00281;MGYG000003821_01555;MGYG000000216_02769;MGYG000004296_01202;MGYG000002966_01692;MGYG000001338_02424;MGYG000002186_02647;MGYG000000184_00686;MGYG000001602_02146;MGYG000000050_00432;MGYG000001027_02054;MGYG000000213_00152 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3XZQ5@572511|Blautia 0.6818181818181818 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 8.87 0.6818181818181818 acsE 1.0 - 1.0 2.1.1.258 1.0 ko:K15023 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R02289,R10243 1.0 RC00004,RC00113,RC01144,RC02871,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pterin_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the N(5) group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein.-!-Involved, together with EC 1.2.7.4 and EC 2.3.1.169, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea. (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein] = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)ALNDLAAIK MGYG000000301_01012;MGYG000002528_00367;MGYG000004785_01017;MGYG000000002_02120;MGYG000003012_02911;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000001338_02547;MGYG000000133_02283;MGYG000003335_00316;MGYG000000213_00374;MGYG000000806_01930 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.9230769230769231 186801|Clostridia 1.0 C 0.9230769230769231 Psort location Cytoplasmic, score 0.9230769230769231 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1348870 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AQAHIDAGAK MGYG000002999_00356;MGYG000002540_02142;MGYG000000375_01483;MGYG000001311_02933;MGYG000003012_02911;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000000205_02269;MGYG000003695_01114;MGYG000000145_03615;MGYG000002445_01920;MGYG000000193_03247;MGYG000002944_01470;MGYG000003110_00098;MGYG000004809_00788;MGYG000004799_00704;MGYG000000002_02120;MGYG000001065_01088;MGYG000002946_02881;MGYG000002966_00075;MGYG000002131_02428;MGYG000000242_02076;MGYG000003335_00316;MGYG000000233_00345;MGYG000001577_01888;MGYG000000099_02094;MGYG000003702_00925;MGYG000000252_01324;MGYG000000365_00999;MGYG000000301_01012;MGYG000004087_02290;MGYG000000312_01508;MGYG000001688_03910;MGYG000002972_00451;MGYG000000423_01499;MGYG000002857_01020;MGYG000002212_00259;MGYG000004296_01958;MGYG000000213_00374;MGYG000000281_02732;MGYG000000179_02084;MGYG000000142_01979;MGYG000000263_01341;MGYG000002095_00148;MGYG000004411_00321;MGYG000000806_01930;MGYG000001505_01467;MGYG000000212_01474;MGYG000001661_02632;MGYG000004785_01017;MGYG000000171_00850;MGYG000001757_00726;MGYG000001338_02547;MGYG000001602_01805;MGYG000003074_01265;MGYG000000133_02283;MGYG000002298_02410;MGYG000004246_01300;MGYG000001315_01699;MGYG000002035_01208 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.47540983606557374 186801|Clostridia 0.8852459016393442 C 0.7704918032786885 Psort location Cytoplasmic, score 0.47540983606557374 gap 0.9672131147540983 - 0.9672131147540983 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AQAHIEAGAK MGYG000000044_01948;MGYG000003312_01022;MGYG000003831_00170;MGYG000002455_02200;MGYG000003542_01626;MGYG000000354_00611;MGYG000002556_00846;MGYG000004748_00450;MGYG000003202_00946;MGYG000001345_01069;MGYG000003681_00790;MGYG000000196_00479;MGYG000001643_00773;MGYG000004464_00783;MGYG000002478_03999;MGYG000001313_02393;MGYG000002549_00455;MGYG000002737_00455;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000003469_01436;MGYG000001493_05257;MGYG000002281_04045;MGYG000000673_01725;MGYG000002905_02083;MGYG000000198_04065;MGYG000000941_01985 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.7857142857142857 976|Bacteroidetes 0.9285714285714286 C 0.8571428571428571 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.9285714285714286 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 314981 0 0 0 0 177000 0 0 0 0 0 0 0 0 0 159544 0 0 0 0 557539 0 0 0 0 421413 0 0 0 0 461796 0 0 0 0 316903 0 0 218364 0 0 0 0 760936 0 0 0 0 0 0 0 0 0 259186 0 0 0 0 459205 0 0 0 0 681146 0 0 0 0 186192 0 0 0 0 87005 0 0 281928 0 0 0 0 407205 0 0 0 0 0 0 0 0 0 176777 0 0 0 0 423335 0 0 0 0 407877 0 0 0 0 161232 0 0 0 0 200609 0 0 64890 0 0 0 0 177195 0 0 0 0 0 0 0 0 0 147306 0 0 0 0 0 0 0 0 0 81049 0 0 0 0 68771 0 0 0 0 250624 0 0 192213 0 0 0 0 85927 0 0 0 0 0 0 0 0 0 373567 0 0 0 0 482029 0 0 0 0 154068 0 0 0 0 0 0 0 0 0 138812 -(Carbamidomethyl)AQAHINAGAR MGYG000000251_00555;MGYG000000280_02459;MGYG000003694_01737;MGYG000002974_01418;MGYG000004140_01100;MGYG000001186_01925;MGYG000000484_01691;MGYG000000398_00286;MGYG000001683_01827;MGYG000001748_01525;MGYG000000271_03250;MGYG000004271_00554;MGYG000001319_00348;MGYG000003828_01578;MGYG000000404_00344;MGYG000002517_01026;MGYG000000153_00303;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000140_01181 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.8095238095238095 186801|Clostridia 1.0 G 0.9047619047619048 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8095238095238095 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 182637 0 0 0 0 0 192433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 51950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371759 0 0 0 0 0 342681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 764970 0 0 0 0 0 707797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 85890 0 0 0 0 0 111592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AQIGVTTSEYDKEK MGYG000002156_00861 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550585|m__MGYG000002156 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2N6RJ@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1002351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)ASVPFFK MGYG000004271_02656;MGYG000003215_00001;MGYG000000280_01601;MGYG000000271_02750;MGYG000000404_01534;MGYG000002517_02338;MGYG000000154_01456;MGYG000000076_01479 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,3NGQJ@46205|Pseudobutyrivibrio 0.875 186801|Clostridia 1.0 I 1.0 Enoyl-CoA hydratase/isomerase 0.875 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)AWAAEHVVGVAK MGYG000000201_02350;MGYG000001310_02359 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 0.5 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 0.5 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)DAGYLTR MGYG000001666_00329;MGYG000004797_04274;MGYG000000074_01764;MGYG000000358_00901;MGYG000000196_03983;MGYG000001630_01150;MGYG000004763_01698;MGYG000001489_05036;MGYG000001346_01525;MGYG000002438_02330;MGYG000002478_00805 domain d__Bacteria 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 0.45454545454545453 976|Bacteroidetes 0.9090909090909091 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 0.9090909090909091 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 0.9090909090909091 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1547397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)DELGIKGAFTSAGMDGSSDWR MGYG000002298_00512;MGYG000004733_01177 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3XZHY@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 GH49 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2778665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)DIHIIDLQK MGYG000003504_00560 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-314|g__CAG-1435|s__CAG-1435 sp003537755|m__MGYG000003504 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,267MF@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2496064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5130945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)DKLVEAIR MGYG000000179_02087;MGYG000004464_00924 domain d__Bacteria 1.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,267NF@186813|unclassified Clostridiales 0.5 186801|Clostridia 0.5 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 - 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Metalloenzyme,PglZ,Phosphodiest,iPGM_N 0.5 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1268507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)EAILADAQAK MGYG000004719_01421;MGYG000002492_01520;MGYG000000271_00139;MGYG000004271_00266;MGYG000000489_00322;MGYG000002517_01451 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 C 0.8333333333333334 Psort location Cytoplasmic, score 0.8333333333333334 - 0.8333333333333334 - 1.0 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 GARP,HrpE 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4207544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)EAINDAMK MGYG000003702_00925 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eisenbergiella|s__Eisenbergiella sp900066775|m__MGYG000003702 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2854094 0 0 0 0 3262647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)EKAQAHIEAGAK MGYG000000044_01948;MGYG000001643_00773;MGYG000004464_00783;MGYG000003831_00170;MGYG000002478_03999;MGYG000000243_01331;MGYG000000273_02725;MGYG000000354_00611;MGYG000003469_01436;MGYG000000673_01725;MGYG000002556_00846;MGYG000003202_00946;MGYG000003681_00790;MGYG000002905_02083;MGYG000000941_01985 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.7333333333333333 976|Bacteroidetes 1.0 C 0.7333333333333333 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)ELKNGGKIQLVGFGTFEVSER MGYG000001338_00344 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3Y0HQ@572511|Blautia 1.0 186801|Clostridia 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hup 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2110426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)ELLSEYDFPGDDTPIIR MGYG000003166_01350;MGYG000000022_02283;MGYG000002040_01212;MGYG000002272_01482;MGYG000002619_00483;MGYG000001300_00280;MGYG000002641_00069 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)FGLADAGNIYGR MGYG000001300_02567;MGYG000001642_00033;MGYG000000280_02177;MGYG000000185_00279;MGYG000002978_00618;MGYG000002651_00281;MGYG000004087_02957;MGYG000002279_01466;MGYG000003486_01767;MGYG000004733_02577;MGYG000002298_00566;MGYG000002274_02337;MGYG000000252_02565;MGYG000000090_02004;MGYG000003266_00234;MGYG000000028_02056;MGYG000001315_02833;MGYG000002775_00932;MGYG000003361_00996;MGYG000000142_03199;MGYG000004740_00564;MGYG000001502_02222;MGYG000002445_01002;MGYG000000383_00104;MGYG000002040_00064;MGYG000001086_01260;MGYG000001567_00737;MGYG000001737_00599;MGYG000004519_00910;MGYG000000693_01345;MGYG000000212_00356;MGYG000000213_02746;MGYG000002272_02328;MGYG000000031_03298;MGYG000004681_00802;MGYG000002528_02771;MGYG000000195_01901;MGYG000000146_02288;MGYG000001456.1_01574;MGYG000000171_00165;MGYG000001338_01027;MGYG000000100_00277;MGYG000001303_02138;MGYG000002545_01885;MGYG000000291_00793;MGYG000000269_00514;MGYG000001636_01145;MGYG000000216_02897;MGYG000000038_00531;MGYG000002641_02488;MGYG000002050_00805;MGYG000002312_02592;MGYG000000140_01570;MGYG000002992_00682;MGYG000002065_00609;MGYG000003291_00536;MGYG000004679_00587;MGYG000000022_02103;MGYG000001645_01495;MGYG000003891_00287;MGYG000000164_02014;MGYG000001779_00982;MGYG000002919_00234;MGYG000002619_00737 domain d__Bacteria 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia 0.296875 186801|Clostridia 0.609375 E 0.890625 Psort location Cytoplasmic, score 9.98 0.328125 metY 0.546875 - 1.0 2.5.1.49 0.890625 ko:K01740 0.890625 ko00270,ko01100,map00270,map01100 0.890625 - 1.0 R01287,R04859 0.890625 RC00020,RC02821,RC02848 0.890625 ko00000,ko00001,ko01000 0.890625 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 0.609375 - 1.0 - 1.0 - 1.0 - 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 0.890625 0.890625 0.890625 0.890625 Cysteine and methionine metabolism;Metabolic pathways 0.890625 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GAGEKVNLDPAESVAYLIGK MGYG000004719_02002;MGYG000000271_02101 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GAVHVTDYSNASR MGYG000001315_01111;MGYG000004733_00600;MGYG000004839_01969;MGYG000004689_01707;MGYG000002312_03080;MGYG000000213_01204;MGYG000000268_00688;MGYG000000245_01078;MGYG000003552_01937;MGYG000000145_02287;MGYG000000249_01696;MGYG000000142_00490;MGYG000004630_02409;MGYG000000164_01754;MGYG000004087_02483;MGYG000000271_02110;MGYG000002517_00523;MGYG000002186_01069;MGYG000000205_00108;MGYG000000501_01232;MGYG000000263_01173 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,27V84@189330|Dorea 0.3333333333333333 186801|Clostridia 1.0 F 0.42857142857142855 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GAVVLPHGTGK MGYG000000139_00679;MGYG000002992_01641;MGYG000000095_03286;MGYG000002963_02025;MGYG000001698_00708;MGYG000004839_01328;MGYG000000171_01515;MGYG000003694_02390;MGYG000002193_01562;MGYG000002052_00803;MGYG000004762_01114;MGYG000000050_01365;MGYG000000201_02339;MGYG000004733_01323;MGYG000001027_00236;MGYG000000179_05050;MGYG000003695_01274;MGYG000000242_00769;MGYG000000152_04608;MGYG000003142_01874;MGYG000000028_00271;MGYG000000119_02509;MGYG000001571_03428;MGYG000000076_03547;MGYG000004680_00227;MGYG000002966_01277;MGYG000000251_00050;MGYG000000249_00046;MGYG000004296_01660;MGYG000001338_03534;MGYG000000387_00298;MGYG000000154_02173;MGYG000004634_00431;MGYG000000212_02414;MGYG000002552_01596;MGYG000001622_01986;MGYG000003425_04472;MGYG000001186_01608;MGYG000004604_00078;MGYG000001714_01227;MGYG000000087_02073;MGYG000004735_02574;MGYG000000268_01636;MGYG000002445_02953;MGYG000000269_00794;MGYG000002772_00853;MGYG000001303_01960;MGYG000000118_00315;MGYG000004630_01085;MGYG000001607_01030;MGYG000001687_02063;MGYG000001315_01189;MGYG000002517_00192;MGYG000002098_01611;MGYG000002286_02461;MGYG000000146_01144;MGYG000001748_00537;MGYG000002202_02038;MGYG000000271_03296;MGYG000000164_01129;MGYG000004380_01359;MGYG000000031_00709;MGYG000000153_01114;MGYG000002845_01899;MGYG000004714_00474;MGYG000000136_02022;MGYG000001689_01643;MGYG000002170_01019;MGYG000001065_00817;MGYG000003335_00786;MGYG000002393_01693;MGYG000000278_00573;MGYG000001439_02403;MGYG000002492_00336;MGYG000004519_00684;MGYG000001374_02225;MGYG000004717_00220;MGYG000001319_01772;MGYG000002298_02666;MGYG000000287_00086;MGYG000001658_02414;MGYG000000078_01689;MGYG000002670_00356;MGYG000000002_03534;MGYG000000198_05828;MGYG000000364_02037;MGYG000001660_01137;MGYG000002596_02351;MGYG000001683_01776;MGYG000004747_01843;MGYG000004246_01047;MGYG000000080_02021;MGYG000002279_01914;MGYG000000281_01919;MGYG000001688_00640;MGYG000003116_00418;MGYG000002312_03039;MGYG000000142_01261;MGYG000000562_01874;MGYG000002836_02018;MGYG000000187_02021;MGYG000002985_00771;MGYG000002528_01114;MGYG000000489_01684;MGYG000002835_01623;MGYG000000018_02173;MGYG000000140_01578;MGYG000000205_00361;MGYG000000274_00236;MGYG000000200_03209;MGYG000002072_00516;MGYG000001141_02451;MGYG000001379_00716;MGYG000003215_01171;MGYG000000133_01992;MGYG000004359_00731;MGYG000001637_00078;MGYG000004087_00328;MGYG000000252_00576 domain d__Bacteria 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 0.3277310924369748 186801|Clostridia 0.9831932773109243 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 0.9915966386554622 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GEFLLR MGYG000000532_01862 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-510|s__CAG-510 sp000434615|m__MGYG000000532 1.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,27IWP@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Aminoacyl tRNA synthetase class II, N-terminal domain 1.0 pheS 1.0 - 1.0 6.1.1.20 1.0 ko:K01889 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Phe_tRNA-synt_N,tRNA-synt_2d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GFGIAMHTLDGGR MGYG000000080_01475;MGYG000002528_02667;MGYG000000204_00801;MGYG000000127_04022;MGYG000001793_01807;MGYG000002945_00737;MGYG000001615_04301;MGYG000000139_01931;MGYG000001564_00904;MGYG000000164_00686;MGYG000001315_01868;MGYG000001814_02502;MGYG000001617_02045;MGYG000000028_00943;MGYG000003486_02522 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.4 186801|Clostridia 1.0 C 0.6 acyl-CoA dehydrogenase 0.4666666666666667 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 414206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GFPIAMHTLDGGR MGYG000000076_01275;MGYG000003694_00879;MGYG000001777_01058;MGYG000000280_01471;MGYG000000153_01461;MGYG000000136_00900;MGYG000001637_02229;MGYG000000271_02102;MGYG000000404_01797;MGYG000004271_00233;MGYG000000389_02149;MGYG000001186_01721;MGYG000002517_00542;MGYG000000489_01025;MGYG000001319_02235;MGYG000002670_01509;MGYG000002492_00659;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.6111111111111112 186801|Clostridia 1.0 C 0.8888888888888888 acyl-CoA dehydrogenase 0.6111111111111112 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GGGYTGQAGAIR MGYG000002992_01001;MGYG000002772_00676;MGYG000000249_02000;MGYG000004879_02699;MGYG000000262_00186;MGYG000000133_01062;MGYG000001439_02724;MGYG000001338_00476;MGYG000000213_02255;MGYG000000077_00860;MGYG000000171_01362;MGYG000000164_02705;MGYG000001186_01285;MGYG000000212_00914;MGYG000000271_01696;MGYG000000216_00022;MGYG000001141_01300;MGYG000002145_02436;MGYG000000806_00037;MGYG000002517_00289;MGYG000000187_01724;MGYG000000078_01638;MGYG000000038_02280;MGYG000001303_03153;MGYG000000562_01950;MGYG000000200_02986;MGYG000000159_01079;MGYG000001379_00626;MGYG000001652_01613;MGYG000004431_01330;MGYG000001315_01067;MGYG000000251_00358;MGYG000000201_02593;MGYG000000142_00583;MGYG000000301_01483;MGYG000000245_02146;MGYG000002945_03245;MGYG000004719_01698;MGYG000001374_02193;MGYG000004869_00363;MGYG000002312_00529;MGYG000002393_00234;MGYG000003012_00713;MGYG000002492_02720;MGYG000000050_00963;MGYG000000280_01393;MGYG000002966_01975;MGYG000000002_00954;MGYG000002279_00145;MGYG000000489_02402 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae 0.52 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 0.9 rpsI 1.0 - 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GGIVFAPKPR MGYG000004525_00964;MGYG000004487_01021;MGYG000002964_01300;MGYG000001476_03271;MGYG000000972_00369;MGYG000002707_00964;MGYG000001193_00545;MGYG000003819_01159;MGYG000004784_00635;MGYG000000099_02400;MGYG000002143_00708;MGYG000001616_02450;MGYG000004715_01182;MGYG000001733_00032;MGYG000003686_01083;MGYG000000668_02069;MGYG000002159_00259;MGYG000003589_01463;MGYG000001576_02390;MGYG000001328_03280;MGYG000002057_00234;MGYG000004736_00666;MGYG000004726_03515;MGYG000001685_00537;MGYG000004124_01019;MGYG000003278_01675;MGYG000000036_00624;MGYG000002315_01089;MGYG000004252_00062;MGYG000002115_00710;MGYG000000392_01460;MGYG000002926_00535;MGYG000002552_01618;MGYG000003142_01862;MGYG000002944_01721;MGYG000001500_00883;MGYG000003581_01700;MGYG000001781_02370;MGYG000002116_01180;MGYG000004201_00826;MGYG000001577_00648;MGYG000002229_01222;MGYG000000484_00176;MGYG000002794_00540;MGYG000004667_05135;MGYG000002953_00592;MGYG000004482_00988;MGYG000003459_00671;MGYG000002857_00040;MGYG000003453_00779;MGYG000003770_00994;MGYG000002727_02380;MGYG000004276_01040;MGYG000001502_00411;MGYG000000078_01672;MGYG000002993_00662;MGYG000001319_01323 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,2N6EK@216572|Oscillospiraceae 0.3508771929824561 186801|Clostridia 0.9824561403508771 J 0.9473684210526315 Forms part of the polypeptide exit tunnel 0.5964912280701754 rplD 0.9473684210526315 - 0.9824561403508771 - 0.9649122807017544 ko:K02926 0.9298245614035088 ko03010,map03010 0.9473684210526315 M00178 0.9473684210526315 - 0.9649122807017544 - 0.9649122807017544 br01610,ko00000,ko00001,ko00002,ko03011 0.9473684210526315 - 0.9824561403508771 - 1.0 - 1.0 Ribosomal_L4 0.9298245614035088 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9649122807017544 0.9649122807017544 0.9649122807017544 0.9649122807017544 Ribosome 0.9473684210526315 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1115220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GGM(Oxidation)TSHAAVVAR MGYG000000236_00181;MGYG000002006_01658;MGYG000002685_01892;MGYG000004482_00393;MGYG000002298_01806;MGYG000002079_00687;MGYG000001415_02125;MGYG000002727_00240;MGYG000004680_00577;MGYG000004760_00878;MGYG000002560_01450;MGYG000001688_03814;MGYG000001698_00702;MGYG000004891_00190;MGYG000000378_00784;MGYG000001313_01473;MGYG000002103_01314;MGYG000002208_00666;MGYG000003116_01723;MGYG000004726_03204;MGYG000001374_00487;MGYG000001577_00663;MGYG000002517_01243;MGYG000002963_02777;MGYG000000074_01177;MGYG000002139_00077;MGYG000002933_01184;MGYG000004764_00308;MGYG000001665_01593;MGYG000000696_02522;MGYG000003801_01123;MGYG000002185_00531;MGYG000002545_01217;MGYG000000187_00493;MGYG000003236_01337;MGYG000000371_01679;MGYG000000262_01988;MGYG000003366_01811;MGYG000004468_01251;MGYG000000044_00817;MGYG000003223_01338;MGYG000000357_01205;MGYG000001641_02069;MGYG000000233_02503;MGYG000003221_00300;MGYG000004869_04101;MGYG000000111_01891;MGYG000000690_00823;MGYG000002455_03526;MGYG000003684_03260;MGYG000004630_00154;MGYG000001789_01569;MGYG000004797_01193;MGYG000001871_00692;MGYG000000194_03193;MGYG000002040_00906;MGYG000004296_00104;MGYG000000118_00274;MGYG000000039_02141;MGYG000002133_02142;MGYG000000312_02404;MGYG000000356_00934;MGYG000001496_03326;MGYG000001562_02560;MGYG000003821_02000;MGYG000000121_02531;MGYG000001502_03051;MGYG000002293_00252;MGYG000001356_00630;MGYG000004547_00698;MGYG000003312_03561;MGYG000000177_02155;MGYG000000231_00504;MGYG000002105_00879;MGYG000000002_01928;MGYG000004763_00142;MGYG000002965_00229;MGYG000002875_01930;MGYG000004667_00970;MGYG000001687_00537;MGYG000004735_00207;MGYG000003374_01797;MGYG000003921_00033;MGYG000002670_01671;MGYG000002590_00564;MGYG000001757_01805;MGYG000003979_01382;MGYG000002057_00345;MGYG000000728_00587;MGYG000002274_02693;MGYG000001531_01607;MGYG000000252_02480;MGYG000001136_01739;MGYG000000359_00714;MGYG000001306_00064;MGYG000000168_01244;MGYG000001345_02795;MGYG000000242_00224;MGYG000000212_00440;MGYG000003013_00135;MGYG000002794_01254;MGYG000004718_01489;MGYG000004733_01907;MGYG000003409_02325;MGYG000002580_00394;MGYG000003164_00707;MGYG000004545_00538;MGYG000004642_01131;MGYG000000170_00404;MGYG000000175_01356;MGYG000000076_02377;MGYG000001607_01964;MGYG000000159_02392;MGYG000000387_01345;MGYG000000184_00575;MGYG000000941_02014;MGYG000000281_03419;MGYG000002702_00763;MGYG000001489_03803;MGYG000000223_02468;MGYG000003899_02226;MGYG000004469_00050;MGYG000000154_00436;MGYG000000398_01662;MGYG000002102_01725;MGYG000002707_01357;MGYG000000045_00432;MGYG000001707_02428;MGYG000000255_02207;MGYG000001497_00744;MGYG000002212_01829;MGYG000002194_01689;MGYG000004871_01103;MGYG000002845_01363;MGYG000000198_00250;MGYG000002278_00689;MGYG000001732_00266;MGYG000002821_00845;MGYG000002945_01502;MGYG000003583_00265;MGYG000000133_02955;MGYG000004145_00052;MGYG000002191_00387;MGYG000003693_01476;MGYG000002279_01986;MGYG000000251_01169;MGYG000000153_02081;MGYG000001748_00979;MGYG000003166_00833;MGYG000000377_01737;MGYG000003628_00298;MGYG000000636_01370;MGYG000001191_01302;MGYG000002966_02744;MGYG000003656_02122;MGYG000000989_01009;MGYG000002219_00344;MGYG000003952_01418;MGYG000002925_01270;MGYG000003268_01036;MGYG000000202_02337;MGYG000001637_01169;MGYG000000087_02439;MGYG000001623_01332;MGYG000003285_00970;MGYG000000463_01481;MGYG000003222_00337;MGYG000000013_03892;MGYG000001597_00394;MGYG000001615_00145;MGYG000003662_00980;MGYG000002098_00511;MGYG000002609_02142;MGYG000001780_04079;MGYG000002926_01683;MGYG000002247_01703;MGYG000003681_00659;MGYG000003542_01534;MGYG000003539_00598;MGYG000000205_02701;MGYG000000152_05136;MGYG000003362_00767;MGYG000000028_00797;MGYG000001315_01921;MGYG000001300_02837;MGYG000004663_01541;MGYG000000743_01457;MGYG000000003_01500;MGYG000000352_00288;MGYG000004380_01725;MGYG000002025_01833;MGYG000004732_02304;MGYG000004475_00310;MGYG000003422_01232;MGYG000001328_00836;MGYG000002721_00889;MGYG000001541_00690;MGYG000000369_01165;MGYG000002549_01561;MGYG000001699_00078;MGYG000003702_00366;MGYG000002552_02286;MGYG000001346_03147;MGYG000003697_00469;MGYG000000404_01435;MGYG000002492_01692;MGYG000004784_01123;MGYG000003486_02360;MGYG000003512_01246;MGYG000004743_00400;MGYG000002218_01508;MGYG000000489_00801;MGYG000000394_00907;MGYG000000915_00888;MGYG000003446_00860;MGYG000003133_02846;MGYG000004464_01604;MGYG000000142_02834;MGYG000003891_00830;MGYG000002082_00584;MGYG000004866_01031;MGYG000000400_01783;MGYG000002099_01951;MGYG000000222_00273;MGYG000004487_00114;MGYG000000171_00241;MGYG000000280_02154;MGYG000003819_01577;MGYG000000325_02351;MGYG000004087_01282;MGYG000000245_03386;MGYG000003547_00119;MGYG000000258_01879;MGYG000000036_01410;MGYG000000179_00100;MGYG000003074_00103;MGYG000001367_01857;MGYG000003311_01206;MGYG000000217_00685;MGYG000001787_02320;MGYG000002934_01311;MGYG000000098_03346;MGYG000002026_01365;MGYG000000982_00638;MGYG000004634_00605;MGYG000001647_00185;MGYG000001423_03022;MGYG000001738_01167;MGYG000000201_02673;MGYG000003279_00708;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domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.22285714285714286 186801|Clostridia 0.7314285714285714 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8457142857142858 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9885714285714285 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 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MGYG000000022_02788;MGYG000000196_02017;MGYG000004558_03187;MGYG000003450_00463;MGYG000004810_00381;MGYG000002578_00642;MGYG000001754_01214;MGYG000001338_02151;MGYG000001675_00187;MGYG000001646_00500;MGYG000001666_00300;MGYG000002052_00198;MGYG000003202_01304;MGYG000001310_01399;MGYG000003432_00750;MGYG000003694_01656;MGYG000002675_00002;MGYG000001378_01176;MGYG000000077_02459;MGYG000002114_00088;MGYG000002229_00282;MGYG000002528_02478;MGYG000000701_00789;MGYG000001388_04287;MGYG000004594_00959;MGYG000000140_01464;MGYG000001461_02244;MGYG000002523_01400;MGYG000001157_01952;MGYG000001319_00729;MGYG000000145_01088;MGYG000000230_01645;MGYG000000115_00663;MGYG000002143_00035;MGYG000004317_00074;MGYG000000392_01615;MGYG000000243_00277;MGYG000003001_01218;MGYG000004271_01396;MGYG000001786_00858;MGYG000001660_00969;MGYG000002393_00923;MGYG000000127_02901;MGYG000000131_01163;MGYG000002935_00059;MGYG000000467_01756;MGYG000000268_00698;MGYG000002905_00879;MGYG000004517_00262;MGYG000000383_01314;MGYG000001733_00637;MGYG000004526_01655;MGYG000003708_02672;MGYG000003812_01931;MGYG000000354_02206;MGYG000003363_02147;MGYG000001756_01779;MGYG000004845_02015;MGYG000004879_02866;MGYG000001439_01567;MGYG000000806_02014;MGYG000001563_00781;MGYG000000174_00191;MGYG000002035_01821;MGYG000002304_00988;MGYG000000271_00388;MGYG000000417_00539;MGYG000002159_01291;MGYG000000278_00304;MGYG000004785_01840;MGYG000000031_02405;MGYG000000215_00031;MGYG000002478_03849;MGYG000002753_00264;MGYG000001619_00896;MGYG000000249_01089;MGYG000001505_00106;MGYG000000084_02524;MGYG000001364_03292;MGYG000003307_01519;MGYG000003469_00516;MGYG000001564_02842;MGYG000000099_03199;MGYG000002953_01784;MGYG000002438_03578;MGYG000004658_00597;MGYG000002007_01910;MGYG000002596_00549;MGYG000003142_00686;MGYG000004606_00249;MGYG000001661_00974;MGYG000000673_01172;MGYG000000164_00358;MGYG000003381_00006;MGYG000002224_02000;MGYG000000089_02490;MGYG000001255_00900;MGYG000001651_00429;MGYG000002126_00460;MGYG000003660_00478 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.22285714285714286 186801|Clostridia 0.7314285714285714 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8457142857142858 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9885714285714285 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GIDKAEIKR MGYG000002291_02272;MGYG000001630_01142;MGYG000000243_01988;MGYG000003691_01713 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GIDKAEVKR MGYG000001770_01653;MGYG000002293_00521;MGYG000002603_01782;MGYG000003374_00521;MGYG000002080_00527;MGYG000003697_01485 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0050@1|root,COG0050@2|Bacteria,4P1C5@976|Bacteroidetes,2FX1Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 295571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 731218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1163846 0 958471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GIDKNEIKR MGYG000000042_01421;MGYG000002905_00001;MGYG000000138_00665;MGYG000001661_02666;MGYG000004848_00666;MGYG000001789_00154;MGYG000000215_00564;MGYG000001925_01419;MGYG000000273_00431;MGYG000003701_03123;MGYG000000054_03933;MGYG000003681_02037;MGYG000000098_02017;MGYG000002470_01245;MGYG000002438_02321;MGYG000002556_01332;MGYG000001346_01533;MGYG000001313_00097;MGYG000004629_00424;MGYG000001763_00317;MGYG000000254_02569;MGYG000000044_01721;MGYG000002418_00753;MGYG000000117_01463;MGYG000002834_01866 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.48 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10816618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GIIVAPSK MGYG000002156_01453;MGYG000002720_01498;MGYG000004487_01572;MGYG000001824_01089;MGYG000002794_01483;MGYG000004475_01017 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,2N73E@216572|Oscillospiraceae 0.8333333333333334 186801|Clostridia 1.0 E 0.8333333333333334 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 0.8333333333333334 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GITINTSHVEYQTANR MGYG000000042_01421;MGYG000004756_01173;MGYG000001415_02515;MGYG000002438_02321;MGYG000004658_01205;MGYG000000053_00908;MGYG000000243_01988;MGYG000000013_02251;MGYG000004006_00433;MGYG000001562_01075;MGYG000000074_01773;MGYG000001789_00154;MGYG000003279_00951;MGYG000000273_00431;MGYG000001655_02933;MGYG000004763_01689;MGYG000002418_00753;MGYG000002291_02272;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000000168_03211 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 0.47619047619047616 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 317584 0 0 0 0 0 0 806770 0 0 0 0 0 0 0 0 335987 0 284608 0 0 0 0 0 497469 0 0 0 0 0 0 0 0 0 0 0 0 0 470086 0 0 314072 0 425627 0 577272 0 0 0 0 0 0 0 0 440315 0 0 0 0 0 0 0 591085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166969 0 839484 0 0 0 0 0 0 0 0 0 0 317544 0 0 0 0 0 456545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 528060 0 0 630833 0 352546 0 332699 0 0 0 0 0 0 0 0 294021 0 400246 0 0 0 0 0 560877 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GLIVAPSK MGYG000002720_01498;MGYG000002794_01483;MGYG000001675_00492 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,2N73E@216572|Oscillospiraceae 0.6666666666666666 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 0.6666666666666666 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GLLAYLK MGYG000000031_02386;MGYG000002298_00958;MGYG000000301_00463;MGYG000004733_02569;MGYG000000133_01737;MGYG000001314_02376;MGYG000000233_02689;MGYG000000200_01442;MGYG000001496_01208;MGYG000001698_03460;MGYG000001338_01245;MGYG000002274_00875;MGYG000000212_01974;MGYG000000171_00631;MGYG000000249_01938;MGYG000001310_00639;MGYG000001300_02374;MGYG000001602_02044;MGYG000004558_01263;MGYG000002438_01817;MGYG000000002_01947;MGYG000000184_00337;MGYG000001797_03146;MGYG000002966_03339;MGYG000000146_00467;MGYG000004869_04229;MGYG000004039_00267;MGYG000004735_01967;MGYG000002596_02036;MGYG000000142_02815;MGYG000002992_00137;MGYG000001970_01507;MGYG000000245_00310;MGYG000000245_02213;MGYG000000271_00460;MGYG000000245_00823;MGYG000002837_01061;MGYG000002492_01768;MGYG000002517_01666;MGYG000004519_01512;MGYG000000076_03321;MGYG000000038_02212;MGYG000000356_01426;MGYG000000119_01472;MGYG000000389_00299;MGYG000000268_01202;MGYG000000213_01727;MGYG000004271_01061;MGYG000003452_00551;MGYG000002279_00584;MGYG000003486_01734;MGYG000000201_02701;MGYG000000205_00957;MGYG000000216_02226;MGYG000004733_03076;MGYG000001186_00210 domain d__Bacteria 1.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia 0.23214285714285715 186801|Clostridia 0.75 J 0.6071428571428571 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 0.6071428571428571 rpsO 0.6071428571428571 - 1.0 - 0.9642857142857143 ko:K02956 0.6071428571428571 ko03010,map03010 0.6071428571428571 M00178,M00179 0.6071428571428571 - 0.7857142857142857 - 0.7857142857142857 br01610,ko00000,ko00001,ko00002,ko03011 0.6071428571428571 - 0.9464285714285714 - 1.0 - 1.0 Ribosomal_S15 0.6071428571428571 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9642857142857143 0.9642857142857143 0.9642857142857143 0.9642857142857143 Ribosome 0.6071428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3130645 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GMILC(Carbamidomethyl)KPGQVK MGYG000001789_00154;MGYG000000243_01988 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GNFLMDELAR MGYG000000271_03444;MGYG000004271_01228 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GPVASIC(Carbamidomethyl)YQGLMR MGYG000002560_02257;MGYG000001364_01116;MGYG000001787_02427;MGYG000004479_00625;MGYG000002933_00140;MGYG000000042_00775;MGYG000001306_01045;MGYG000003680_01392;MGYG000001599_02810;MGYG000004824_00039;MGYG000000781_01742;MGYG000003693_02590;MGYG000001783_00207;MGYG000002478_02040;MGYG000000442_00581;MGYG000000243_02202;MGYG000004763_00520;MGYG000000273_01192;MGYG000004797_01477 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 0.8947368421052632 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 0.8947368421052632 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 659162 0 0 0 0 645653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293361 0 0 0 0 494078 0 0 0 0 1940811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 854768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552681 0 0 0 0 734498 0 0 0 0 723787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 547978 0 0 0 0 514340 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GQKVNPHGLR MGYG000001365_00964;MGYG000002965_00664;MGYG000000249_01545;MGYG000004250_01651;MGYG000001367_00355;MGYG000001714_01322;MGYG000004517_00981;MGYG000004271_00022;MGYG000000177_02166;MGYG000001602_00386;MGYG000002953_00597;MGYG000002279_01066;MGYG000000187_01752;MGYG000000278_00919;MGYG000004769_00445;MGYG000001754_00745;MGYG000000362_00706;MGYG000000195_02127;MGYG000002619_02380;MGYG000002517_02867;MGYG000000515_01665;MGYG000001300_02209;MGYG000002298_00334;MGYG000002304_02165;MGYG000000071_01873;MGYG000000217_01260;MGYG000002528_01845;MGYG000002057_00239;MGYG000000140_01889;MGYG000001606_00218;MGYG000000198_04893;MGYG000000089_01490;MGYG000001315_01342;MGYG000002969_00164;MGYG000002312_02271;MGYG000000194_02276;MGYG000004680_02465;MGYG000000141_02175;MGYG000000139_02402;MGYG000004735_01595;MGYG000000262_00152;MGYG000003324_00575;MGYG000000334_01214;MGYG000000028_01616;MGYG000004593_00047;MGYG000004699_00276;MGYG000000050_01178;MGYG000000153_02048;MGYG000002105_00235;MGYG000002036_00649;MGYG000002154_01336;MGYG000003311_01156;MGYG000003876_00398;MGYG000000164_02758;MGYG000000022_02034;MGYG000000463_00749;MGYG000003422_00860;MGYG000000077_02604;MGYG000004558_00370;MGYG000001314_01374;MGYG000004317_00970;MGYG000000271_01067;MGYG000004736_00671;MGYG000000364_01346;MGYG000000146_01045;MGYG000000231_02152;MGYG000001576_02395;MGYG000001619_00828;MGYG000001338_02801;MGYG000004087_00388;MGYG000001626_01890;MGYG000004784_00630;MGYG000002966_02569;MGYG000004726_03510;MGYG000000258_00287;MGYG000003465_00837;MGYG000002290_02018;MGYG000000119_00095;MGYG000001191_00912;MGYG000000080_02261;MGYG000000171_01899;MGYG000004718_00068;MGYG000003215_00869;MGYG000002545_01134;MGYG000002276_00874;MGYG000000145_02795;MGYG000003895_00039;MGYG000003581_01705;MGYG000000245_02644;MGYG000000076_02814;MGYG000003147_00986;MGYG000001439_02149;MGYG000002113_00808;MGYG000000251_01825;MGYG000002159_00254;MGYG000002234_01447;MGYG000004681_01723;MGYG000004022_00110;MGYG000000591_02148;MGYG000002659_00451;MGYG000002492_00381;MGYG000001954_02309;MGYG000004296_00395;MGYG000000002_00876;MGYG000000179_04594;MGYG000004642_00857;MGYG000004727_00011;MGYG000000182_00577;MGYG000000099_02395 domain d__Bacteria 1.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae 0.2018348623853211 186801|Clostridia 0.908256880733945 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 0.9908256880733946 rpsC 0.9908256880733946 - 0.981651376146789 - 1.0 ko:K02982 0.9908256880733946 ko03010,map03010 0.9908256880733946 M00178,M00179 0.9908256880733946 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.9908256880733946 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 0.9908256880733946 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.9908256880733946 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GQVLAKPGTVTC(Carbamidomethyl)HR MGYG000000271_03365;MGYG000000532_02409;MGYG000000245_03248;MGYG000002670_00364;MGYG000001814_01592;MGYG000001319_01764 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GTWDAVHAQAK MGYG000004482_00318 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4|s__ER4 sp900546295|m__MGYG000004482 1.0 COG0031@1|root,COG0031@2|Bacteria,1TZEW@1239|Firmicutes,249RW@186801|Clostridia,2N6W5@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Pyridoxal-phosphate dependent 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PALP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 876007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80136 0 0 386616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GVDKNEIKR MGYG000000196_03974;MGYG000000236_01807;MGYG000004763_01689;MGYG000000013_02251;MGYG000002281_02290 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GVNRDQIVR MGYG000000271_03365;MGYG000002670_00364;MGYG000001319_01764 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GVWVFC(Carbamidomethyl)EQR MGYG000002105_00077;MGYG000002610_00221;MGYG000003166_01338;MGYG000000195_01569;MGYG000004487_01101;MGYG000003291_01730;MGYG000002794_00291;MGYG000000022_01320;MGYG000002707_00928;MGYG000001500_03165;MGYG000001824_01146;MGYG000000099_01610;MGYG000002059_01404;MGYG000002224_01329;MGYG000003937_01087;MGYG000004866_01546;MGYG000002651_00003;MGYG000000127_00940;MGYG000002040_01719;MGYG000001761_00373;MGYG000001157_00997;MGYG000003869_00111;MGYG000002619_02235;MGYG000000090_01517;MGYG000001300_00291;MGYG000004732_01392;MGYG000002287_01182;MGYG000002156_02067;MGYG000003899_01132;MGYG000001356_00011;MGYG000002223_00611;MGYG000001255_01110;MGYG000002287_00701;MGYG000004475_01038;MGYG000002720_01216;MGYG000002274_00049;MGYG000003770_01063 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 0.6216216216216216 186801|Clostridia 0.918918918918919 C 1.0 Electron transfer flavoprotein FAD-binding domain 0.6216216216216216 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 0.6216216216216216 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 5963920 0 0 0 0 0 0 4580095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2284218 0 0 0 0 2824027 0 2945233 0 0 0 0 0 0 0 0 0 0 0 0 2950549 0 2518740 0 0 0 2495733 0 0 0 0 3082236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)GYRPQFYFR MGYG000003096_01037;MGYG000004704_00398;MGYG000000303_01575;MGYG000004565_01266;MGYG000003189_00640;MGYG000004694_00667;MGYG000004893_00932;MGYG000003324_00542;MGYG000002563_00522;MGYG000001507_06245;MGYG000004685_00908;MGYG000001739_00819;MGYG000003184_03610;MGYG000003363_01661;MGYG000003411_00716;MGYG000004594_01333;MGYG000001234_01151;MGYG000003185_01074;MGYG000001623_00993;MGYG000003142_01879;MGYG000002994_01317;MGYG000003208_02857;MGYG000002563_00509;MGYG000003266_00392;MGYG000004119_01204;MGYG000002515_03657;MGYG000003189_01066;MGYG000003142_01865;MGYG000002557_00102;MGYG000004800_00190;MGYG000001713_03599;MGYG000004769_00437;MGYG000003851_00676;MGYG000003022_00748;MGYG000000371_01541;MGYG000000349_00457;MGYG000002098_01616;MGYG000003274_01474;MGYG000004528_00894;MGYG000003868_01133;MGYG000001359_01254;MGYG000004722_01495;MGYG000000333_00136;MGYG000001692_03322;MGYG000002996_00986;MGYG000003753_00317;MGYG000002506_03686;MGYG000003352_00730;MGYG000002447_00587;MGYG000001365_00649;MGYG000002854_00111;MGYG000004769_00412;MGYG000001524_01606;MGYG000002485_02622;MGYG000003022_00735;MGYG000003528_02124;MGYG000004724_00878;MGYG000004893_01944;MGYG000000802_00776;MGYG000000372_00001;MGYG000000365_00508;MGYG000002535_04656;MGYG000002515_03208;MGYG000003372_03275;MGYG000000291_00377;MGYG000000266_00259;MGYG000001464_00103;MGYG000002447_00574;MGYG000000449_00614;MGYG000002506_02966;MGYG000000120_01190;MGYG000001404_04883;MGYG000000375_01434;MGYG000002901_00528;MGYG000002514_02415;MGYG000001436_02249;MGYG000003891_00382;MGYG000001525_00035;MGYG000000157_01091;MGYG000003394_01668;MGYG000000490_01981;MGYG000001784_02227;MGYG000003110_00861;MGYG000002507_00346;MGYG000001485_02164;MGYG000002195_01684;MGYG000000479_00469;MGYG000001991_00383;MGYG000003465_01528;MGYG000001638_00284;MGYG000003977_00001;MGYG000003868_01166;MGYG000000024_03409;MGYG000001677_00114;MGYG000000432_00837;MGYG000003170_00035;MGYG000001590_00854;MGYG000002972_00178;MGYG000002098_00731;MGYG000002514_01953;MGYG000002912_01340;MGYG000000121_02189;MGYG000001567_01738;MGYG000003441_00074;MGYG000003389_01825;MGYG000004694_00680;MGYG000002502_01846;MGYG000000945_00137;MGYG000002854_00124;MGYG000002830_01189;MGYG000003185_01053;MGYG000003170_00048;MGYG000004746_00230;MGYG000000121_03149;MGYG000001665_01696;MGYG000004657_01190;MGYG000003504_00096;MGYG000000405_00711;MGYG000001646_01118;MGYG000003514_00785;MGYG000002970_01555;MGYG000001007_01315;MGYG000002659_00459;MGYG000004047_00605 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CUFV@84998|Coriobacteriia 0.12903225806451613 186801|Clostridia 0.41935483870967744 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9032258064516129 tuf 1.0 - 0.9032258064516129 - 1.0 ko:K02358 0.9919354838709677 - 0.9919354838709677 - 0.9919354838709677 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9919354838709677 - 0.9919354838709677 - 1.0 - 0.9435483870967742 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9919354838709677 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)HTIDNLDNISENTSSAESR MGYG000003694_00680;MGYG000003694_02093 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter faecis|m__MGYG000003694 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 652115 0 0 0 0 1748007 0 0 0 0 882111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)IDAFIR MGYG000004839_01245 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__GCA-900066135|s__|m__MGYG000004839 1.0 COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Acetolactate synthase, small subunit 1.0 ilvN 1.0 - 1.0 2.2.1.6 1.0 ko:K01653 1.0 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R00006,R00014,R00226,R03050,R04672,R04673,R08648 1.0 RC00027,RC00106,RC01192,RC02744,RC02893 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS10025 1.0 ACT,ACT_5,ALS_ss_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetolactate synthase. alpha-acetolactate synthetase. The reaction shown is in the pathway of biosynthesis of valine.-!-The enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine.-!-Formerly EC 4.1.3.18. H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Butanoate metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;C5-Branched dibasic acid metabolism;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1386468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1571383 0 0 0 0 0 0 -(Carbamidomethyl)IDPLIGLK MGYG000000142_00116;MGYG000000262_00026 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3XYSW@572511|Blautia 0.5 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)IEEVVAK MGYG000000213_02548;MGYG000000053_00926;MGYG000001787_01168;MGYG000002082_01733;MGYG000001364_00770;MGYG000000003_02420;MGYG000001346_02612;MGYG000002549_00764;MGYG000003539_00163;MGYG000001338_01196;MGYG000004185_02468;MGYG000000074_01808;MGYG000001630_00403;MGYG000000105_03037;MGYG000000224_00951;MGYG000002133_01046;MGYG000003542_01378;MGYG000003469_00458;MGYG000000200_03517;MGYG000001313_02533;MGYG000001750_00845;MGYG000004658_01241;MGYG000001789_01807;MGYG000001420_00031;MGYG000001835_00447;MGYG000002560_01566;MGYG000003922_03262;MGYG000002905_00830;MGYG000000273_00915;MGYG000004536_01855;MGYG000002108_00182;MGYG000003279_00867;MGYG000000243_01732;MGYG000000354_00645;MGYG000003681_01014;MGYG000004479_00195;MGYG000001360_00725;MGYG000000042_00518;MGYG000001429_01341;MGYG000004763_00341 domain d__Bacteria 1.0 COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia,4AKD2@815|Bacteroidaceae 0.475 976|Bacteroidetes 0.925 S 0.825 Endoribonuclease that initiates mRNA decay 0.925 rny 0.925 - 1.0 - 0.925 ko:K18682 0.925 ko03018,map03018 0.925 - 1.0 - 0.925 - 0.925 ko00000,ko00001,ko01000,ko03019 0.925 - 1.0 - 1.0 - 1.0 DUF3552,HD,KH_1 0.925 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.925 0.925 0.925 0.925 RNA degradation 0.925 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)IESVAR MGYG000004464_01712 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Barnesiellaceae|g__Barnesiella|s__Barnesiella sp900542255|m__MGYG000004464 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22WR5@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5845798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)IGEGLHTVEAGEGSIIVDGK MGYG000000392_01140 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Ruminococcus_E|s__Ruminococcus_E sp003521625|m__MGYG000000392 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1153943 0 0 0 0 1190018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)IIAYLK MGYG000002478_02508;MGYG000003922_03572;MGYG000002171_00339;MGYG000000196_03221;MGYG000000243_02815 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FNVV@200643|Bacteroidia,4AM0Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 pepD_1 1.0 - 1.0 - 1.0 ko:K01270 1.0 ko00480,ko01100,map00480,map01100 1.0 - 1.0 R00899,R04951 1.0 RC00096,RC00141 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Glutathione metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 3181591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)IINEPTAAALAYGLDNEKEQK MGYG000003366_02143;MGYG000000175_03865;MGYG000003355_02854;MGYG000001615_03019;MGYG000000255_01223;MGYG000000249_01105;MGYG000000181_00382;MGYG000002989_00635;MGYG000000171_01795;MGYG000000152_05170;MGYG000001689_04245;MGYG000002492_01740;MGYG000002772_01367;MGYG000000271_02474;MGYG000000038_00915;MGYG000003694_01621;MGYG000000142_01918;MGYG000000233_02915;MGYG000004842_01083;MGYG000004547_01722;MGYG000000287_03181;MGYG000001303_03339;MGYG000000133_02344;MGYG000004642_01648;MGYG000004271_00836;MGYG000000198_01270;MGYG000002393_02714;MGYG000000141_02906;MGYG000002234_00982;MGYG000003422_00551;MGYG000003012_00270;MGYG000002276_02250;MGYG000000123_02326;MGYG000004285_01970;MGYG000000200_01023;MGYG000002286_01322;MGYG000000002_00433;MGYG000004869_03374;MGYG000000278_01716;MGYG000000139_01467;MGYG000000281_00071;MGYG000000179_03775;MGYG000000245_00866;MGYG000001310_00050;MGYG000001247_01563;MGYG000001315_00535;MGYG000004733_01142;MGYG000004087_01928;MGYG000004735_00816;MGYG000000127_03199;MGYG000002279_01669;MGYG000001619_00480;MGYG000002256_00937;MGYG000001698_00974;MGYG000001065_01063;MGYG000000164_00503;MGYG000000153_02121;MGYG000002517_00989;MGYG000003821_01669;MGYG000001374_00251;MGYG000001496_00605;MGYG000001617_02693;MGYG000004762_01166;MGYG000000217_02058 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.375 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)ILPLEKNPDFVGTRK MGYG000004271_01228 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)ILVTLLHEMQKR MGYG000004525_00228;MGYG000002953_03277;MGYG000002670_01511;MGYG000002727_00924;MGYG000004769_00635;MGYG000003215_01534;MGYG000001356_02661;MGYG000002156_00131;MGYG000002720_01849;MGYG000000164_00683;MGYG000001814_02499;MGYG000001616_02334;MGYG000001637_02269;MGYG000001500_00694;MGYG000004628_02379;MGYG000001711_01126;MGYG000003589_00853;MGYG000002492_00657;MGYG000002099_02958;MGYG000000204_00804;MGYG000000997_00552;MGYG000000077_02464;MGYG000002926_00108;MGYG000002143_01933;MGYG000000280_01473;MGYG000002485_00796;MGYG000003074_00590;MGYG000002673_02531;MGYG000000389_02151;MGYG000000262_02231;MGYG000001793_01810;MGYG000004271_00231;MGYG000000245_02019;MGYG000000271_02104;MGYG000002517_00540;MGYG000004475_01257;MGYG000001315_01871 domain d__Bacteria 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,2N6SP@216572|Oscillospiraceae 0.32432432432432434 186801|Clostridia 0.918918918918919 I 1.0 Belongs to the thiolase family 0.5135135135135135 thlA 0.918918918918919 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)ISIKDTR MGYG000003374_00261;MGYG000000117_02272;MGYG000004733_01798;MGYG000004469_01045;MGYG000001211_00617;MGYG000001777_01726;MGYG000001356_01504;MGYG000003539_00358;MGYG000002534_00332;MGYG000003352_01970;MGYG000000146_00711;MGYG000000258_01582;MGYG000000463_00946;MGYG000004735_01737;MGYG000003282_01713;MGYG000002082_01050;MGYG000002042_01173;MGYG000001607_01410;MGYG000001489_01493;MGYG000000187_01632;MGYG000002438_01730;MGYG000004629_01198;MGYG000000201_03541;MGYG000000196_01785;MGYG000000164_00409;MGYG000004830_00640;MGYG000000231_00052;MGYG000003022_01459;MGYG000000369_01798;MGYG000000233_02484;MGYG000003621_01331;MGYG000003984_00341;MGYG000000182_00198;MGYG000002274_02526;MGYG000003546_01574;MGYG000000154_00030;MGYG000001637_01423;MGYG000000325_00559;MGYG000000268_00827;MGYG000000312_01303;MGYG000003353_02290;MGYG000001164_02313;MGYG000003063_03432;MGYG000001531_02004;MGYG000000398_00128;MGYG000002203_00985;MGYG000002772_01784;MGYG000002532_00097;MGYG000002279_00233;MGYG000000038_01227;MGYG000003204_01991;MGYG000001374_02763;MGYG000001065_01729;MGYG000002494_02064;MGYG000002619_01587;MGYG000002549_03009;MGYG000000249_00741;MGYG000000255_01277;MGYG000000359_02374;MGYG000001456.1_02555;MGYG000001754_01464;MGYG000001346_02112;MGYG000004271_00099;MGYG000003694_01770;MGYG000003695_03029;MGYG000000174_04897;MGYG000000074_00119;MGYG000001319_00792;MGYG000004757_00433;MGYG000001608_01372;MGYG000004638_00366;MGYG000001733_01436;MGYG000000140_02799;MGYG000002312_02047;MGYG000002007_01949;MGYG000000150_00934;MGYG000000650_01803;MGYG000002113_00157;MGYG000004296_01453;MGYG000000184_00227;MGYG000002290_01715;MGYG000000242_01153;MGYG000000193_03368;MGYG000000084_02464;MGYG000002298_02427;MGYG000000217_00585;MGYG000004822_01333;MGYG000003554_01585;MGYG000000673_00661;MGYG000000031_03161;MGYG000000212_01493;MGYG000001447_01495;MGYG000000622_01660;MGYG000000171_00870;MGYG000001302.1_01989;MGYG000002445_00666;MGYG000000271_02023;MGYG000002506_03025;MGYG000002641_01086;MGYG000004762_00297;MGYG000004558_00126;MGYG000002145_02237;MGYG000000078_00400;MGYG000000236_04489;MGYG000000022_02853;MGYG000000170_00471;MGYG000000562_01754;MGYG000002966_02362;MGYG000002212_01428;MGYG000002455_01424;MGYG000001337_04099;MGYG000000133_00275;MGYG000001602_01331;MGYG000000414_01708;MGYG000000044_02644;MGYG000000404_00613;MGYG000000589_00852;MGYG000003363_00033;MGYG000001315_01422;MGYG000001345_04617;MGYG000000142_01678;MGYG000001300_02311;MGYG000000412_00523;MGYG000004658_01689;MGYG000003291_00979;MGYG000001655_03297;MGYG000004536_00920;MGYG000001551_02111;MGYG000003681_02208;MGYG000003702_01556;MGYG000002517_01999;MGYG000002535_04602;MGYG000000050_00443;MGYG000000003_00469;MGYG000004747_00335;MGYG000001415_01110;MGYG000003937_01472;MGYG000001338_02508;MGYG000002721_02375;MGYG000003252_01528 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia 0.37142857142857144 186801|Clostridia 0.5928571428571429 H 0.9428571428571428 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 0.9928571428571429 pckA 0.9928571428571429 - 0.6428571428571429 4.1.1.49 0.9785714285714285 ko:K01610 0.9785714285714285 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 0.9785714285714285 M00003,M00170 0.9785714285714285 R00341 0.9785714285714285 RC00002,RC02741 0.9785714285714285 ko00000,ko00001,ko00002,ko01000 0.9785714285714285 - 1.0 - 1.0 - 0.9714285714285714 PEPCK_ATP 0.9928571428571429 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 0.9785714285714285 0.9785714285714285 0.9785714285714285 0.9785714285714285 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.9785714285714285 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)ISTEIGKSPVQVNEAAGFVVNR MGYG000001157_01000;MGYG000004866_01549 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 758184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1406795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1158768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 787703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 711052 0 0 0 0 -(Carbamidomethyl)ITEIYEGTSEVQR MGYG000002229_02144;MGYG000003589_02740;MGYG000000076_01275;MGYG000001714_01569;MGYG000003554_00067;MGYG000004740_00273;MGYG000002673_02001;MGYG000001615_04301;MGYG000002673_01997;MGYG000004610_01222;MGYG000000153_01461;MGYG000002057_01870;MGYG000002086_01703;MGYG000001637_02229;MGYG000003686_01365;MGYG000002926_00639;MGYG000000489_01025;MGYG000002670_01509;MGYG000002492_00659;MGYG000001299_00669;MGYG000004628_02311;MGYG000002528_02667;MGYG000001797_02605;MGYG000002964_00486;MGYG000001008_02486;MGYG000000312_02425;MGYG000001302.1_00495;MGYG000000127_04022;MGYG000002944_01934;MGYG000001793_01807;MGYG000000139_01931;MGYG000000532_01532;MGYG000001356_00009;MGYG000000378_01674;MGYG000001655_02978;MGYG000004475_01030;MGYG000000271_02102;MGYG000000404_01797;MGYG000004271_00233;MGYG000004039_00586;MGYG000002794_01608;MGYG000001814_02502;MGYG000001186_01721;MGYG000001199_01107;MGYG000000028_00943;MGYG000000223_02387;MGYG000001319_02235;MGYG000000262_02234;MGYG000003486_02522;MGYG000000154_01282;MGYG000002035_01743;MGYG000004487_00391;MGYG000004288_00482;MGYG000002485_00623;MGYG000002882_00479;MGYG000002143_01787;MGYG000000205_02133;MGYG000000378_01663;MGYG000002156_01815;MGYG000000164_00686;MGYG000001500_03163;MGYG000004893_01404;MGYG000003074_00587;MGYG000004196_00482;MGYG000002974_01094;MGYG000000099_01612;MGYG000001502_00068;MGYG000000255_01556;MGYG000001315_01868;MGYG000003753_00746;MGYG000002720_01506;MGYG000001617_02045;MGYG000003649_02139;MGYG000003828_00184;MGYG000000080_01475;MGYG000000018_00071;MGYG000000077_02467;MGYG000000204_00801;MGYG000003694_00879;MGYG000001777_01058;MGYG000002278_01893;MGYG000000121_03669;MGYG000000280_01471;MGYG000002945_00737;MGYG000000930_01661;MGYG000001327_01004;MGYG000001749_01450;MGYG000001460_01831;MGYG000000136_00900;MGYG000001683_00189;MGYG000000086_01916;MGYG000000389_02149;MGYG000002934_01789;MGYG000001675_00811;MGYG000004762_01001;MGYG000002517_00542 domain d__Bacteria 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2N683@216572|Oscillospiraceae 0.17708333333333334 186801|Clostridia 0.8333333333333334 I 0.53125 Acyl-CoA dehydrogenase, C-terminal domain 0.3645833333333333 bcd 0.875 - 1.0 1.3.8.1 0.90625 ko:K00248 0.90625 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 0.9375 - 1.0 R01175,R01178,R02661,R03172,R04751 0.9375 RC00052,RC00068,RC00076,RC00120,RC00148 0.9375 ko00000,ko00001,ko01000 0.9375 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 0.6770833333333334 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 0.90625 0.90625 0.90625 0.90625 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 0.9375 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)KDITGLGLK MGYG000004468_00169 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900539755|m__MGYG000004468 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)KIEAAVDTK MGYG000003681_02191 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3298246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)KLLDQGEAGDNVGLLLR MGYG000000042_01421;MGYG000000196_03974;MGYG000000138_00665;MGYG000004704_00398;MGYG000001661_02666;MGYG000001630_01142;MGYG000003424_00456;MGYG000001789_00154;MGYG000000273_00431;MGYG000000236_01807;MGYG000003701_03123;MGYG000000054_03933;MGYG000004763_01689;MGYG000003681_02037;MGYG000000098_02017;MGYG000002291_02272;MGYG000002281_02290;MGYG000002470_01245;MGYG000002438_02321;MGYG000001346_01533;MGYG000001313_00097;MGYG000000243_01988;MGYG000000013_02251;MGYG000001780_03476;MGYG000001562_01075;MGYG000002455_03884;MGYG000003497_00215;MGYG000000044_01721;MGYG000002418_00753;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.4666666666666667 976|Bacteroidetes 0.9666666666666667 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)KSDLTGAVSAISADK MGYG000003520_00430 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__UBA932|g__RC9|s__RC9 sp900769145|m__MGYG000003520 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AWE5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2328065 0 0 0 0 2499584 0 0 0 0 2045847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850805 0 0 0 0 932510 0 0 0 0 753708 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)KTVVTGIEMFRK MGYG000004743_00349;MGYG000000251_00064;MGYG000003236_02455;MGYG000000121_02189;MGYG000000099_01234;MGYG000003486_01055;MGYG000002772_01895;MGYG000002492_00344;MGYG000000255_02009;MGYG000002052_00232;MGYG000000164_01096;MGYG000001606_01669;MGYG000001698_04050;MGYG000001310_01963 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.2857142857142857 186801|Clostridia 0.9285714285714286 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)LFVVDAFC(Carbamidomethyl)GANKDTR MGYG000000268_00827;MGYG000001733_01436;MGYG000000179_01927;MGYG000000347_00991;MGYG000000140_02799;MGYG000002312_02047;MGYG000001615_04787;MGYG000002670_02163;MGYG000000150_00934;MGYG000000562_01754;MGYG000004296_01453;MGYG000000184_00227;MGYG000000245_00268;MGYG000002772_01784;MGYG000000463_00946;MGYG000000404_00613;MGYG000000084_02464;MGYG000000217_00585;MGYG000000187_01632;MGYG000000142_01678;MGYG000000201_03541;MGYG000000031_03161;MGYG000002492_01827;MGYG000001311_00844;MGYG000000249_00741;MGYG000000255_01277;MGYG000000095_02727;MGYG000000233_02484;MGYG000004740_01746;MGYG000004891_01172;MGYG000002445_00666;MGYG000002517_01999;MGYG000000198_03217;MGYG000004271_00099;MGYG000000271_02023;MGYG000003694_01770;MGYG000003695_03029;MGYG000004558_00126;MGYG000002145_02237;MGYG000004747_00335;MGYG000000489_00960;MGYG000003486_01799;MGYG000000078_00400;MGYG000000251_02509;MGYG000001637_01423;MGYG000003937_01472;MGYG000001338_02508;MGYG000000325_00559 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia 0.6875 186801|Clostridia 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)LGYDDATIADYLAK MGYG000004642_00725 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,36FMV@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 PFAM L-carnitine dehydratase bile acid-inducible protein F 1.0 hadA 1.0 - 1.0 2.8.3.24 1.0 ko:K20882 1.0 - 1.0 - 1.0 R11462 1.0 RC00014,RC00137 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_transf_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 (R)-2-hydroxy-4-methylpentanoate CoA-transferase. - The enzyme, characterized from the bacterium Peptoclostridium difficile, participates in an L-leucine fermentation pathway.-!-The reaction proceeds via formation of a covalent anhydride intermediate between a conserved aspartate residue and the acyl group of the CoA thioester substrate. (R)-2-hydroxy-4-methylpentanoate + 4-methylpentanoyl-CoA = (R)-2-hydroxy- 4-methylpentanoyl-CoA + 4-methylpentanoate. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1594056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)LIAYLK MGYG000002478_02508;MGYG000002171_00339;MGYG000000243_02815 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FNVV@200643|Bacteroidia,4AM0Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 pepD_1 1.0 - 1.0 - 1.0 ko:K01270 1.0 ko00480,ko01100,map00480,map01100 1.0 - 1.0 R00899,R04951 1.0 RC00096,RC00141 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Glutathione metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1983138 0 0 0 0 2202369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3294908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)LIDGGYDGK MGYG000000217_02098;MGYG000001310_01635;MGYG000002247_02055 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,27IZ4@186928|unclassified Lachnospiraceae 0.6666666666666666 186801|Clostridia 1.0 P 1.0 TOBE domain 0.6666666666666666 ugpC_1 1.0 - 1.0 - 1.0 ko:K10112 1.0 ko02010,map02010 1.0 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1 1.0 - 1.0 - 1.0 ABC_tran,TOBE,TOBE_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4272409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)LLDEAQAGDNIGALLR MGYG000000080_02058;MGYG000000171_02844;MGYG000002279_01932;MGYG000000201_03875;MGYG000001688_04229;MGYG000004735_00884;MGYG000000280_01200;MGYG000000198_01165;MGYG000001315_01207;MGYG000000133_02991;MGYG000001602_02247;MGYG000001310_01963;MGYG000003273_00234;MGYG000000140_01590;MGYG000003142_01879;MGYG000002528_01098;MGYG000004680_02443;MGYG000002609_01147;MGYG000002202_00030;MGYG000000263_00836;MGYG000001619_01314;MGYG000000179_00920;MGYG000000216_02406;MGYG000002290_01325;MGYG000004296_01668;MGYG000001607_01045;MGYG000001141_02439;MGYG000003142_01865;MGYG000000251_00064;MGYG000001338_03373;MGYG000000139_00697;MGYG000000142_00171;MGYG000001528_00736;MGYG000000404_00531;MGYG000004087_00551;MGYG000001439_02427;MGYG000002417_01244;MGYG000000164_01096;MGYG000002126_00299;MGYG000002234_01026;MGYG000000212_03313;MGYG000001698_04050;MGYG000003074_01359;MGYG000000032_01232;MGYG000002837_02416;MGYG000000193_02083;MGYG000002212_00196;MGYG000000249_00026;MGYG000004799_01385;MGYG000002136_02858;MGYG000004630_01824;MGYG000002286_02469;MGYG000001814_01592;MGYG000000262_00030;MGYG000003486_01055;MGYG000002772_01895;MGYG000001617_01406;MGYG000002596_02296;MGYG000004733_01211 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 0.3220338983050847 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 584343 0 0 0 0 0 0 0 0 0 0 630928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520573 0 0 0 0 0 0 0 0 0 0 348112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)LLDQGEAGDNVGLLLR MGYG000000042_01421;MGYG000000196_03974;MGYG000000138_00665;MGYG000004704_00398;MGYG000001661_02666;MGYG000001630_01142;MGYG000003424_00456;MGYG000001789_00154;MGYG000000273_00431;MGYG000000236_01807;MGYG000003701_03123;MGYG000000054_03933;MGYG000004763_01689;MGYG000003681_02037;MGYG000000098_02017;MGYG000002291_02272;MGYG000002281_02290;MGYG000002470_01245;MGYG000002438_02321;MGYG000001346_01533;MGYG000001313_00097;MGYG000000243_01988;MGYG000000013_02251;MGYG000001780_03476;MGYG000001562_01075;MGYG000002455_03884;MGYG000003497_00215;MGYG000000044_01721;MGYG000002418_00753;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.4666666666666667 976|Bacteroidetes 0.9666666666666667 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)LQSLVFDR MGYG000003376_01015 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Leptotrichiaceae|g__Sneathia|s__Sneathia sanguinegens|m__MGYG000003376 1.0 COG0173@1|root,COG0173@2|Bacteria,37982@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) 1.0 aspS 1.0 - 1.0 6.1.1.12 1.0 ko:K01876 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R05577 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 GAD,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon 1.0 - 1.0 - 1.0 - 1.0 GT83 1.0 aspartate--tRNA ligase. aspartyl-tRNA synthetase. - ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4143607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)LSAAEVETLLR MGYG000001415_00893 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,22UVQ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 595685 0 0 0 0 0 0 0 0 0 773301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)LVVFMNK MGYG000000080_02058;MGYG000001389_01588;MGYG000000171_02844;MGYG000004732_02398;MGYG000001673_01975;MGYG000000089_01901;MGYG000001688_04229;MGYG000002619_00483;MGYG000001654_02237;MGYG000004718_00646;MGYG000004735_00884;MGYG000000280_01200;MGYG000003547_00975;MGYG000001714_01291;MGYG000001760_00949;MGYG000000198_01165;MGYG000000392_00966;MGYG000003681_02037;MGYG000000133_02991;MGYG000001389_00024;MGYG000003185_01074;MGYG000003992_01709;MGYG000002202_00030;MGYG000001313_00097;MGYG000003895_00135;MGYG000001619_01314;MGYG000002455_03884;MGYG000000216_02406;MGYG000000348_00283;MGYG000002364_00543;MGYG000000044_01721;MGYG000000034_01346;MGYG000004296_01668;MGYG000003549_00407;MGYG000001469_02077;MGYG000002059_00460;MGYG000001809_00576;MGYG000001652_01300;MGYG000000127_03982;MGYG000001434_01407;MGYG000000258_00266;MGYG000001338_03373;MGYG000001300_00280;MGYG000001611_00087;MGYG000002762_01733;MGYG000000371_01541;MGYG000000255_02009;MGYG000002040_01212;MGYG000000164_01096;MGYG000004826_01022;MGYG000001757_01274;MGYG000002234_01026;MGYG000001606_01669;MGYG000000032_01232;MGYG000002105_00002;MGYG000001359_01254;MGYG000002224_01123;MGYG000002438_02321;MGYG000000036_01380;MGYG000001346_01533;MGYG000002136_02858;MGYG000000262_00030;MGYG000003497_00215;MGYG000004754_01565;MGYG000001412_04734;MGYG000002772_01895;MGYG000003921_01124;MGYG000002052_00232;MGYG000002418_00753;MGYG000001615_01716;MGYG000002695_01057;MGYG000000016_02519;MGYG000002279_01932;MGYG000000138_00665;MGYG000001756_00183;MGYG000000201_03875;MGYG000004547_01366;MGYG000003063_00662;MGYG000000271_03365;MGYG000000867_00556;MGYG000000185_02848;MGYG000001315_01207;MGYG000001602_02247;MGYG000001503_00139;MGYG000001405_04470;MGYG000001310_01963;MGYG000003273_00234;MGYG000000140_01590;MGYG000001065_02730;MGYG000003546_00955;MGYG000000022_02283;MGYG000002470_01245;MGYG000002528_01098;MGYG000003446_00658;MGYG000004680_02443;MGYG000002609_01147;MGYG000001436_02249;MGYG000000263_00836;MGYG000003899_01642;MGYG000003891_00382;MGYG000000179_00920;MGYG000003583_01411;MGYG000001749_02490;MGYG000001779_00600;MGYG000000177_01044;MGYG000002290_01325;MGYG000001531_00906;MGYG000001607_01045;MGYG000001141_02439;MGYG000003166_01350;MGYG000004499_02319;MGYG000000251_00064;MGYG000000233_00807;MGYG000000142_00171;MGYG000002702_01978;MGYG000002912_01340;MGYG000001528_00736;MGYG000000236_01807;MGYG000004087_00551;MGYG000001439_02427;MGYG000003701_03123;MGYG000000242_00282;MGYG000000084_02000;MGYG000002417_01244;MGYG000000028_00215;MGYG000000187_02029;MGYG000002641_00069;MGYG000000733_01034;MGYG000001698_04050;MGYG000000212_03313;MGYG000004558_00415;MGYG000003074_01359;MGYG000003185_01053;MGYG000002837_02416;MGYG000000193_02083;MGYG000002272_01482;MGYG000002212_00196;MGYG000000249_00026;MGYG000003236_02455;MGYG000001780_03476;MGYG000001665_01696;MGYG000004630_01824;MGYG000001814_01592;MGYG000003656_01823;MGYG000003504_00096;MGYG000000405_00711;MGYG000001617_01406;MGYG000003001_00359;MGYG000002596_02296;MGYG000001732_00030;MGYG000000206_00901;MGYG000004733_01211 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.23684210526315788 186801|Clostridia 0.7828947368421053 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9539473684210527 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.9539473684210527 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365895 0 0 0 0 366936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262894 0 0 0 0 357671 0 0 0 0 639707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328247 0 0 0 0 322043 0 0 0 0 463460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278388 0 0 0 0 341888 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)LYEELQAR MGYG000001255_00207 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_F|m__MGYG000001255 1.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3WHP7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) 1.0 tyrS 1.0 - 1.0 6.1.1.1 1.0 ko:K01866 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R02918 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 S4,tRNA-synt_1b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 tyrosine--tRNA ligase. tyrosyl-tRNA synthetase. - ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl- tRNA(Tyr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)NAPAQAK MGYG000000099_02570 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1428231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)NDIALLK MGYG000004158_00685;MGYG000004610_00323;MGYG000000267_01056;MGYG000002492_02947;MGYG000000258_00842;MGYG000000273_02707 domain d__Bacteria 1.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,3VNSJ@526524|Erysipelotrichia 0.3333333333333333 526524|Erysipelotrichia 0.3333333333333333 F 0.3333333333333333 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain glutamine amidotransferase domain) K01952 0.3333333333333333 - 0.6666666666666666 - 1.0 - 0.6666666666666666 - 0.5 - 0.6666666666666666 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.5 - 1.0 - 1.0 - 1.0 AIRS_C,GATase_5 0.3333333333333333 - 1.0 - 1.0 - 1.0 - 0.8333333333333334 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311169 0 0 0 0 218701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5412012 0 0 0 0 0 0 0 0 0 3263679 0 0 4980403 0 0 0 0 5963737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138812405 0 0 0 0 102849188 0 0 0 0 0 0 0 17039024 0 0 0 0 18504308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3735957 0 0 0 0 2900713 0 0 0 0 0 0 0 0 0 0 0 0 155724 0 0 -(Carbamidomethyl)NDLALIK MGYG000003241_00720;MGYG000004158_00685;MGYG000003484_00637 domain d__Bacteria 1.0 COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia,3WHDV@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 0.6666666666666666 KT 0.6666666666666666 Psort location Cytoplasmic, score 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 ko:K02647 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 0.6666666666666666 - 1.0 - 1.0 - 1.0 Diacid_rec,HTH_30 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 2945727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5116221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)NLDNISENTSSAESR MGYG000003694_00680;MGYG000001186_01647;MGYG000002517_00135;MGYG000003694_02093 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1597450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)NVWTVAK MGYG000004758_01534;MGYG000001447_02191;MGYG000001770_00014;MGYG000002737_00822;MGYG000001599_00236;MGYG000002540_00128;MGYG000001056_01383;MGYG000002438_03847;MGYG000004823_00968;MGYG000001372_00314;MGYG000001164_00708;MGYG000003542_00145;MGYG000003367_02063;MGYG000002108_01378;MGYG000004464_01891;MGYG000003202_00327;MGYG000000707_01761;MGYG000003469_00859;MGYG000001415_02017;MGYG000002560_03406;MGYG000002603_00629;MGYG000001302.1_00416;MGYG000003697_00528;MGYG000002293_00151;MGYG000000170_01829;MGYG000000243_00245;MGYG000001789_02629;MGYG000002291_01392;MGYG000003279_02296 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,2FSHF@200643|Bacteroidia,4AQX5@815|Bacteroidaceae 0.41379310344827586 976|Bacteroidetes 1.0 J 1.0 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit 1.0 rplT 1.0 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 1.0 - 1.0 ko:K02887 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1143317 0 0 0 0 4411191 0 0 0 0 1472958 1420833 0 0 0 0 0 0 0 1792609 0 0 0 0 0 -(Carbamidomethyl)PTFNQLVR MGYG000003494_00688;MGYG000001714_01288;MGYG000002212_02586;MGYG000002707_01737;MGYG000004735_00887;MGYG000000089_01904;MGYG000000383_00775;MGYG000000389_02262;MGYG000000252_01072;MGYG000000099_01237;MGYG000003552_02464;MGYG000003694_02395;MGYG000000262_00027;MGYG000001616_00517;MGYG000002105_00005;MGYG000004842_01773;MGYG000000133_02994;MGYG000002234_01029;MGYG000000141_02555;MGYG000003166_01347;MGYG000004526_00642;MGYG000004482_01538;MGYG000002312_02894;MGYG000001683_01330;MGYG000000145_02778;MGYG000000216_02409;MGYG000002274_00060;MGYG000004879_01611;MGYG000004760_00915;MGYG000002517_00202;MGYG000002651_00010;MGYG000000909_01305;MGYG000002993_01299;MGYG000004296_01665;MGYG000002154_01514;MGYG000002835_01672;MGYG000004785_01483;MGYG000000319_00856;MGYG000001300_00283;MGYG000002670_00361;MGYG000000139_00694;MGYG000001338_03376;MGYG000000150_02016;MGYG000000278_00901;MGYG000004317_00569;MGYG000000050_01746;MGYG000004431_01378;MGYG000000164_01099;MGYG000002702_02230;MGYG000001255_01102;MGYG000002289_02135;MGYG000001757_01271;MGYG000002224_01126;MGYG000000312_01433;MGYG000000724_01269;MGYG000001502_01275;MGYG000000280_01197;MGYG000001247_00855;MGYG000000200_01985;MGYG000000258_00263;MGYG000002057_01069;MGYG000003921_01127;MGYG000002492_00341;MGYG000002067_00670;MGYG000002040_01209;MGYG000000127_03985;MGYG000000369_00924;MGYG000002250_00453;MGYG000004747_01983;MGYG000001199_02552;MGYG000002026_01855;MGYG000002025_02452;MGYG000003510_00299;MGYG000003819_01359;MGYG000000271_03362;MGYG000000515_01912;MGYG000002148_02229;MGYG000001707_01473;MGYG000001315_01204;MGYG000001632_01554;MGYG000000217_01432;MGYG000000206_00898;MGYG000004276_00125;MGYG000002966_00549;MGYG000000325_02385;MGYG000000263_00833;MGYG000000562_01880;MGYG000002945_01967;MGYG000000090_01717;MGYG000003899_01645;MGYG000001157_01849;MGYG000002610_00228;MGYG000000028_00229;MGYG000002965_00481;MGYG000004628_02702;MGYG000004869_02963;MGYG000004726_01619;MGYG000001531_00909;MGYG000003589_00203;MGYG000001027_01013;MGYG000003355_03288;MGYG000000301_02342;MGYG000000119_01820;MGYG000001637_00072;MGYG000000194_01013;MGYG000000213_01897;MGYG000001689_01547;MGYG000000031_00744;MGYG000000204_00535;MGYG000000251_00061;MGYG000003074_01356;MGYG000004271_02228;MGYG000002136_02397;MGYG000002247_00116;MGYG000003684_05129;MGYG000000078_01684;MGYG000002641_00066;MGYG000000242_00285;MGYG000002974_01333;MGYG000002953_03324;MGYG000002417_01247;MGYG000000087_02569;MGYG000002251_01053;MGYG000002837_02419;MGYG000000249_00029;MGYG000000989_00161;MGYG000004039_00486;MGYG000001571_02828;MGYG000000274_01838;MGYG000000184_01004;MGYG000001725_00454;MGYG000001374_01221;MGYG000002115_00734;MGYG000001732_00033 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,21ZYE@1506553|Lachnoclostridium 0.5895522388059702 186801|Clostridia 1.0 J 1.0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit 1.0 rpsL 1.0 - 1.0 - 1.0 ko:K02950 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S12_S23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)PTINQLVR MGYG000001514_00036;MGYG000003891_00379;MGYG000003266_00423;MGYG000003352_01409;MGYG000002023_01663;MGYG000002659_01141;MGYG000000557_01073;MGYG000000304_01025;MGYG000001470_03725;MGYG000001086_00480;MGYG000003288_00773;MGYG000002050_01598;MGYG000001384_04564;MGYG000001381_02106;MGYG000000120_01187;MGYG000001410_00771;MGYG000001007_01325;MGYG000001651_00898;MGYG000004653_01146;MGYG000001785_00689;MGYG000000198_01162;MGYG000004565_01263;MGYG000003411_00713;MGYG000002447_00577;MGYG000004780_01212;MGYG000003376_00238;MGYG000000277_00489;MGYG000004540_00956;MGYG000002074_00231;MGYG000004158_01415;MGYG000004788_00776;MGYG000000179_00923;MGYG000000291_01370;MGYG000002315_00744;MGYG000004694_00677;MGYG000001436_02252;MGYG000004594_00890;MGYG000004232_01393;MGYG000003836_00554;MGYG000000269_00800;MGYG000002113_00819;MGYG000001647_00753;MGYG000003449_00702;MGYG000003868_01163;MGYG000002065_00315;MGYG000001991_00380;MGYG000001709_00474;MGYG000001613_01113;MGYG000000188_00929;MGYG000000157_01087;MGYG000002370_00101;MGYG000004647_01364;MGYG000004769_00434;MGYG000003802_01290;MGYG000004681_00045;MGYG000001401_00634;MGYG000001740_00096;MGYG000003441_00071;MGYG000004138_00061;MGYG000003369_00138;MGYG000003391_01660;MGYG000001636_01144;MGYG000002972_00644;MGYG000003324_01495;MGYG000003274_01510;MGYG000001460_03660;MGYG000000182_00588;MGYG000002820_00495;MGYG000003482_02072;MGYG000003170_00045;MGYG000001739_00822;MGYG000004704_00524;MGYG000004606_00606;MGYG000003501_00913;MGYG000004804_01398;MGYG000004728_00755;MGYG000001248_01380;MGYG000000045_02619;MGYG000003512_00649;MGYG000003022_00738;MGYG000000974_00870;MGYG000002986_00445;MGYG000001167_00880;MGYG000001646_01115;MGYG000001486_02525;MGYG000004532_01349;MGYG000004789_01482;MGYG000002919_00397;MGYG000000435_00533;MGYG000003110_00480;MGYG000001365_00343;MGYG000002101_01412;MGYG000001642_00116;MGYG000000802_00741 domain d__Bacteria 1.0 COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4CVWP@84998|Coriobacteriia 0.23404255319148937 186801|Clostridia 0.2553191489361702 J 1.0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit 0.9787234042553191 rpsL 0.9893617021276596 - 0.8404255319148937 - 1.0 ko:K02950 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S12_S23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)PTIQQLVR MGYG000002549_02929;MGYG000002291_02259;MGYG000002935_01235;MGYG000002470_01234;MGYG000001489_02610;MGYG000001562_01941;MGYG000004720_00748;MGYG000004536_01500;MGYG000002203_01143;MGYG000001789_00134;MGYG000001783_02410;MGYG000000673_01519;MGYG000001302.1_01162;MGYG000004658_00150;MGYG000001211_01231;MGYG000000138_02893;MGYG000000415_00047;MGYG000002478_00803;MGYG000000170_00045;MGYG000000029_02785;MGYG000002205_00902;MGYG000000414_01220;MGYG000000003_00091;MGYG000002560_00232;MGYG000001599_01855;MGYG000004185_01167;MGYG000001370_01691;MGYG000003279_01341;MGYG000003367_01248;MGYG000000111_01719;MGYG000001364_02758;MGYG000002675_00602;MGYG000001666_01977;MGYG000004469_01445;MGYG000003362_01941;MGYG000002281_02279;MGYG000001435_00765;MGYG000001415_01613;MGYG000001306_02656;MGYG000000243_01975;MGYG000001346_01523;MGYG000001461_00400;MGYG000002033_01887;MGYG000002455_03895;MGYG000002561_02171;MGYG000000254_00223;MGYG000001835_01812;MGYG000004756_01928;MGYG000003282_01776;MGYG000000054_03854;MGYG000003542_01353;MGYG000002120_01197;MGYG000003221_01989;MGYG000000273_00410;MGYG000000781_00844;MGYG000001787_02682;MGYG000000357_01295;MGYG000003701_04690;MGYG000003363_02295;MGYG000004479_01436;MGYG000000196_03985;MGYG000003693_00189;MGYG000004468_00433;MGYG000002438_02204;MGYG000003812_01484;MGYG000000042_01095;MGYG000001644_00961;MGYG000000144_01718;MGYG000001433_02272;MGYG000001420_02918;MGYG000001546_01213;MGYG000001337_03893;MGYG000003539_00287;MGYG000001925_01428;MGYG000004754_02254;MGYG000004464_01243;MGYG000003546_00263;MGYG000000098_02006;MGYG000002082_00491;MGYG000003202_00814;MGYG000003312_02995;MGYG000000053_00689 domain d__Bacteria 1.0 COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,2FRY7@200643|Bacteroidia 0.6951219512195121 976|Bacteroidetes 0.975609756097561 J 1.0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit 1.0 rpsL 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 0.975609756097561 - 1.0 ko:K02950 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S12_S23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)QLGITTGAQAK MGYG000000356_01643;MGYG000000389_01367;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)QLGITTGQQAK MGYG000004271_01770;MGYG000000271_01499 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)RAQAPVNKDLVTNEEIAADPVAAAMAK MGYG000002492_00484 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC transporter, solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2750619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)SFDSIDNAPEEKER MGYG000000042_01421;MGYG000004756_01173;MGYG000000196_03974;MGYG000002905_00001;MGYG000000138_00665;MGYG000001661_02666;MGYG000000053_00908;MGYG000004006_00433;MGYG000002762_01733;MGYG000000074_01773;MGYG000001789_00154;MGYG000000273_00431;MGYG000000054_03933;MGYG000000236_01807;MGYG000003701_03123;MGYG000000098_02017;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000001503_00139;MGYG000002281_02290;MGYG000004474_01617;MGYG000003546_00955;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000003446_00658;MGYG000001552_00984;MGYG000001346_01533;MGYG000000243_01988;MGYG000000013_02251;MGYG000001562_01075;MGYG000000348_00283;MGYG000003279_00951;MGYG000000414_00662;MGYG000001655_02933;MGYG000000044_01721;MGYG000002418_00753;MGYG000000117_01463;MGYG000000168_03211 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)SIAQQQNTQFK MGYG000000076_01275;MGYG000003694_00879;MGYG000000280_01471;MGYG000000153_01461;MGYG000000136_00900;MGYG000001637_02229;MGYG000000271_02102;MGYG000004271_00233;MGYG000000389_02149;MGYG000001186_01721;MGYG000002492_00659;MGYG000002670_01509;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.6923076923076923 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 0.6923076923076923 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)SVDSIHKELGHIMWDFVGMGR MGYG000002478_01127 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)TAELYADAVK MGYG000002966_00074;MGYG000000325_00585;MGYG000000181_00012 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,36ETN@31979|Clostridiaceae 0.3333333333333333 186801|Clostridia 1.0 F 0.6666666666666666 Belongs to the phosphoglycerate kinase family 0.3333333333333333 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739236 0 0 0 0 0 0 0 1117468 0 0 1127828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2516240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)TAIAIDTIINQK MGYG000003683_01588;MGYG000000636_00623;MGYG000000233_00546;MGYG000001514_01217;MGYG000001292_00312;MGYG000000489_01352;MGYG000003494_01954;MGYG000004757_00191;MGYG000002528_01019;MGYG000001615_03892;MGYG000002459_01436;MGYG000000989_00194;MGYG000000756_00392;MGYG000000271_02345;MGYG000002469_00372;MGYG000004271_01936;MGYG000000205_00317;MGYG000002517_03148;MGYG000001692_03638;MGYG000002492_00114;MGYG000001483_02668;MGYG000001315_02892;MGYG000003684_01754 domain d__Bacteria 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia 0.2608695652173913 186801|Clostridia 0.6086956521739131 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 0.5652173913043478 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 0.9565217391304348 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 0.6086956521739131 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 937080 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)TAIAIDTILNQK MGYG000002397_01410;MGYG000000233_00546;MGYG000001292_00312;MGYG000000489_01352;MGYG000004757_00191;MGYG000004879_02137;MGYG000000562_01722;MGYG000004380_00710;MGYG000004158_00763;MGYG000002469_00372;MGYG000002517_03148;MGYG000001692_03638;MGYG000001652_00148;MGYG000000436_01069;MGYG000002940_00217;MGYG000001543_00550;MGYG000003546_00355;MGYG000002171_00080;MGYG000000135_04341;MGYG000002528_01019;MGYG000004830_01573;MGYG000000389_00984;MGYG000000271_02345;MGYG000000243_00489;MGYG000004667_03726;MGYG000002720_00901;MGYG000003683_01588;MGYG000000997_00488;MGYG000004718_00143;MGYG000003494_01954;MGYG000000385_00450;MGYG000004719_00798;MGYG000002459_01436;MGYG000000989_00194;MGYG000000756_00392;MGYG000004271_01936;MGYG000002492_00114;MGYG000001315_02892;MGYG000003411_00811;MGYG000001525_01549;MGYG000001613_01167;MGYG000001314_01471;MGYG000001777_00205;MGYG000001247_01309;MGYG000000095_01030;MGYG000003147_00102;MGYG000001514_01217;MGYG000001436_02789;MGYG000000974_01373;MGYG000002963_00964;MGYG000000205_00317;MGYG000000187_00874 domain d__Bacteria 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia 0.23076923076923078 186801|Clostridia 0.6153846153846154 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 0.5769230769230769 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 0.9423076923076923 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 0.6538461538461539 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1149098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)TEEELKDFEPDFVVYNASK MGYG000000146_00711 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea|s__Dorea formicigenerans|m__MGYG000000146 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,27V2Q@189330|Dorea 1.0 186801|Clostridia 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 881764 0 0 0 0 1024973 0 0 0 0 1132425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212429 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)TGHEDNAVGGAK MGYG000000013_03050 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp902362375|m__MGYG000000013 1.0 COG0702@1|root,COG0702@2|Bacteria,4NHVQ@976|Bacteroidetes,2FPT0@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 GM 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 774361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)TGLLVDGK MGYG000002961_01417;MGYG000003266_00768 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CUNU@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 Belongs to the pyruvate kinase family 1.0 pyk 1.0 - 1.0 2.7.1.40 1.0 ko:K00873 1.0 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050 1.0 R00200,R00430,R01138,R01858,R02320 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 PK,PK_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate kinase. phosphoenol transphosphorylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Microbial metabolism in diverse environments;Type II diabetes mellitus;Carbon metabolism;Central carbon metabolism in cancer;Metabolic pathways;Viral carcinogenesis;Glycolysis / Gluconeogenesis;Glucagon signaling pathway;Human papillomavirus infection;Purine metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1576117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 186786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)VAGNAAVDFANIDKAPEERER MGYG000000271_03365 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)VFDEFPK MGYG000002549_04148 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,4AP35@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tat pathway signal sequence domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal 1.0 - 1.0 GH109 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1896906 0 0 0 0 0 0 0 0 0 0 1426036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1194166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)VGFQGVTADQAK MGYG000001338_02545;MGYG000000216_01309;MGYG000000301_01010;MGYG000001689_01427;MGYG000000123_03112;MGYG000000031_02179;MGYG000000200_02457;MGYG000002312_02076;MGYG000000142_01977;MGYG000000213_00371;MGYG000000249_01354 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3XYGS@572511|Blautia 0.5454545454545454 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)VLVFAK MGYG000000139_00679;MGYG000000217_01483;MGYG000000095_03286;MGYG000002963_02025;MGYG000001698_00708;MGYG000004839_01328;MGYG000000171_01515;MGYG000003694_02390;MGYG000002193_01562;MGYG000004475_01000;MGYG000003391_01004;MGYG000004762_01114;MGYG000002997_00961;MGYG000000201_02339;MGYG000004733_01323;MGYG000001027_00236;MGYG000000771_00908;MGYG000003695_01274;MGYG000002143_01055;MGYG000003142_01874;MGYG000000028_00271;MGYG000002882_00267;MGYG000000119_02509;MGYG000004487_00621;MGYG000000076_03547;MGYG000002966_01277;MGYG000002042_00904;MGYG000000251_00050;MGYG000004296_01660;MGYG000001338_03534;MGYG000000387_00298;MGYG000000154_02173;MGYG000004634_00431;MGYG000001970_02771;MGYG000000212_02414;MGYG000002552_01596;MGYG000004804_00955;MGYG000003425_04472;MGYG000001186_01608;MGYG000001714_01227;MGYG000004735_02574;MGYG000000226_01968;MGYG000000118_00315;MGYG000004630_01085;MGYG000002116_01221;MGYG000001191_01912;MGYG000002517_00192;MGYG000002944_00189;MGYG000002098_01611;MGYG000003868_01138;MGYG000000477_00308;MGYG000002286_02461;MGYG000004718_01623;MGYG000004158_00989;MGYG000001748_00537;MGYG000002954_00928;MGYG000000271_03296;MGYG000004380_01359;MGYG000000031_00709;MGYG000000262_02173;MGYG000003155_01392;MGYG000000153_01114;MGYG000002213_01020;MGYG000002926_01369;MGYG000004769_00417;MGYG000004714_00474;MGYG000000136_02022;MGYG000001689_01643;MGYG000002057_01279;MGYG000003335_00786;MGYG000000099_00104;MGYG000004702_00047;MGYG000002492_00336;MGYG000004519_00684;MGYG000000982_00331;MGYG000004717_00220;MGYG000001319_01772;MGYG000002298_02666;MGYG000000287_00086;MGYG000001658_02414;MGYG000000078_01689;MGYG000000323_00858;MGYG000003149_00722;MGYG000002670_00356;MGYG000004715_01765;MGYG000000002_03534;MGYG000000364_02037;MGYG000000171_02775;MGYG000001511_00104;MGYG000001660_01137;MGYG000001683_01776;MGYG000004747_01843;MGYG000001651_00889;MGYG000004831_00027;MGYG000000080_02021;MGYG000003702_00729;MGYG000000335_01427;MGYG000003589_00447;MGYG000003116_00418;MGYG000002312_03039;MGYG000000142_01261;MGYG000000562_01874;MGYG000002836_02018;MGYG000001616_00691;MGYG000000187_02021;MGYG000002090_00047;MGYG000002528_01114;MGYG000002707_01484;MGYG000000489_01684;MGYG000003819_01780;MGYG000002835_01623;MGYG000000018_02173;MGYG000000140_01578;MGYG000000071_00478;MGYG000000200_03209;MGYG000002072_00516;MGYG000001141_02451;MGYG000003215_01171;MGYG000004359_00731;MGYG000001637_00078;MGYG000004276_00634;MGYG000000252_00576 domain d__Bacteria 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 0.21311475409836064 186801|Clostridia 0.8770491803278688 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 0.9918032786885246 rplA 0.9918032786885246 - 0.9262295081967213 - 0.9918032786885246 ko:K02863 0.9918032786885246 ko03010,map03010 0.9918032786885246 M00178,M00179 0.9918032786885246 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.9918032786885246 - 1.0 - 1.0 - 1.0 Ribosomal_L1 0.9918032786885246 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9918032786885246 0.9918032786885246 0.9918032786885246 0.9918032786885246 Ribosome 0.9918032786885246 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)VQEVLQR MGYG000002485_02059 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0055@1|root,COG0055@2|Bacteria,3794W@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 - 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)VSAADANVINEDGTR MGYG000000802_00744;MGYG000003266_00420;MGYG000002968_00677;MGYG000002961_00370;MGYG000000188_00926;MGYG000002947_00119;MGYG000003122_00562 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CUED@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)VVAELMPYSGGLKR MGYG000000038_01496;MGYG000002298_00537;MGYG000000233_00988;MGYG000000274_03211;MGYG000001687_01701;MGYG000004733_00602;MGYG000001619_01504;MGYG000000404_00181;MGYG000000171_00188;MGYG000000255_01680;MGYG000002934_01839;MGYG000000271_03443;MGYG000000164_01751;MGYG000000489_01565;MGYG000000233_01586;MGYG000001627_02088;MGYG000001311_02982;MGYG000002517_00256;MGYG000001186_01772;MGYG000000489_00239;MGYG000000154_01591;MGYG000002517_00472;MGYG000001714_00944;MGYG000000121_01384;MGYG000000146_03224;MGYG000000150_04584;MGYG000003695_00823;MGYG000000076_01006;MGYG000000245_01075;MGYG000000249_02125;MGYG000004799_01118;MGYG000000179_02174;MGYG000002279_02523;MGYG000001315_01115;MGYG000004271_01229;MGYG000000087_01969;MGYG000000198_04021;MGYG000000212_00379 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,27UZQ@189330|Dorea 0.34210526315789475 186801|Clostridia 0.9736842105263158 C 0.9736842105263158 FAD dependent oxidoreductase 0.4473684210526316 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_oxidored,Pyr_redox_2,Pyr_redox_3 0.8421052631578947 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)VVTAFVDGWAK MGYG000001300_01498;MGYG000003899_02162;MGYG000002545_02469;MGYG000003291_00077 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 200286 0 0 0 0 307792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 707244 0 0 0 743200 702095 0 0 0 0 0 0 0 0 0 1259976 0 0 625329 0 0 0 0 0 0 0 0 0 0 0 613047 0 0 858020 0 0 0 0 83401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170463 0 0 0 0 1327094 0 0 0 0 161484 0 0 0 0 96749 0 0 0 0 0 -(Carbamidomethyl)YFSVASGGGTGR MGYG000000942_00243;MGYG000003420_01320;MGYG000001658_01116;MGYG000002854_01085;MGYG000004735_00009;MGYG000002802_02025;MGYG000003821_01383;MGYG000000205_02543;MGYG000000802_00613;MGYG000003570_02445;MGYG000004762_01356;MGYG000004517_01958;MGYG000000251_02115;MGYG000002159_02251;MGYG000001925_01569;MGYG000001346_01121;MGYG000000215_01600;MGYG000001871_01775;MGYG000004732_00759;MGYG000004276_01664;MGYG000003160_00232;MGYG000000273_02192;MGYG000003221_02162;MGYG000004604_01207;MGYG000000133_00506;MGYG000001698_03439;MGYG000003474_00100;MGYG000002312_00914;MGYG000002275_01873;MGYG000000515_00648;MGYG000000032_06095;MGYG000000036_01924;MGYG000000258_00155;MGYG000001770_01218;MGYG000002492_01963;MGYG000003450_00728;MGYG000004464_00921;MGYG000002213_00389;MGYG000001615_01983;MGYG000000268_00554;MGYG000000562_01148;MGYG000004779_02234;MGYG000000433_01203;MGYG000000249_02372;MGYG000003446_01092;MGYG000003872_00869;MGYG000004019_01333;MGYG000000223_01510;MGYG000003425_04615;MGYG000001970_01269;MGYG000001786_00203;MGYG000000118_02684;MGYG000000028_01055;MGYG000001027_01414;MGYG000002974_01622;MGYG000001338_01296;MGYG000000263_01515;MGYG000001606_02183;MGYG000004824_01069;MGYG000004055_00746;MGYG000001797_00319;MGYG000002194_01220;MGYG000002444_01680;MGYG000001400_01185;MGYG000002517_01686;MGYG000000212_00326;MGYG000002025_00960;MGYG000001560_01190;MGYG000000245_00061;MGYG000001496_01287;MGYG000001247_02016;MGYG000003012_02646;MGYG000003215_01743;MGYG000000479_02090;MGYG000001806_00888;MGYG000002919_01068;MGYG000002947_01620;MGYG000002880_00963;MGYG000003937_01695;MGYG000000018_02387;MGYG000002293_01605;MGYG000000301_00647;MGYG000003922_03053;MGYG000003693_01584;MGYG000002603_00277;MGYG000002965_01778;MGYG000000378_01853;MGYG000004594_01436;MGYG000002834_01893;MGYG000002438_03055;MGYG000004729_00222;MGYG000003241_01405;MGYG000000312_02568;MGYG000004185_01308;MGYG000000002_01850;MGYG000001636_01063;MGYG000001599_00424;MGYG000000707_02290;MGYG000001319_02415;MGYG000001760_00836;MGYG000004869_01776;MGYG000000391_01131;MGYG000000392_01121;MGYG000002050_01700;MGYG000000013_02686;MGYG000001619_00078;MGYG000004047_01253;MGYG000000387_01305;MGYG000001627_00963;MGYG000000154_00787;MGYG000004630_01662;MGYG000002582_01129;MGYG000003891_01818;MGYG000004561_02010;MGYG000000280_02029;MGYG000004763_01967;MGYG000004493_00376;MGYG000000233_02118;MGYG000004797_02907;MGYG000000140_00469;MGYG000000089_00653;MGYG000000404_00348;MGYG000004733_02764;MGYG000000242_02797;MGYG000004482_01421;MGYG000003470_00018;MGYG000000127_05084;MGYG000004699_02799;MGYG000001415_02505;MGYG000001303_02421;MGYG000002528_00119;MGYG000000136_01348;MGYG000001654_02223;MGYG000002218_00562;MGYG000001604_01691;MGYG000001577_02122;MGYG000001310_00612;MGYG000004140_00114;MGYG000000029_00187;MGYG000001378_03489;MGYG000000045_01847;MGYG000002281_03938;MGYG000000080_01714;MGYG000002098_00644;MGYG000000200_01506;MGYG000000031_02290;MGYG000000142_02731;MGYG000003266_00106;MGYG000000038_01050;MGYG000001300_02120;MGYG000002274_00309;MGYG000003521_00824;MGYG000000039_01269;MGYG000000347_00819;MGYG000002455_00321;MGYG000000269_00015;MGYG000000217_02528;MGYG000000693_00680;MGYG000002985_01044;MGYG000000781_01514;MGYG000000262_01832;MGYG000000187_00466;MGYG000004822_01055;MGYG000001688_03060;MGYG000000198_05683;MGYG000000078_02433;MGYG000000042_01753;MGYG000000196_00899;MGYG000001881_00612;MGYG000001423_03082;MGYG000002286_00349;MGYG000003504_00791;MGYG000003122_01397;MGYG000003335_02616;MGYG000002148_02635;MGYG000003535_01608;MGYG000002224_01738;MGYG000000043_00846;MGYG000000972_01097;MGYG000003589_01350;MGYG000000179_04738;MGYG000002080_00203;MGYG000003851_01315;MGYG000002139_01005;MGYG000002108_00627;MGYG000001697_00682;MGYG000002530_01285;MGYG000000733_01154;MGYG000003483_01370;MGYG000003457_01216;MGYG000003819_00577;MGYG000001763_00631;MGYG000000374_01026;MGYG000001237_02019;MGYG000000989_03267;MGYG000001618_01635;MGYG000001707_00757;MGYG000004317_00089;MGYG000002478_02896;MGYG000001086_01322;MGYG000001785_00655;MGYG000002807_00819 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.18811881188118812 186801|Clostridia 0.5841584158415841 S 0.9554455445544554 GGGtGRT protein 0.2623762376237624 - 0.8861386138613861 - 1.0 - 0.9554455445544554 - 0.9554455445544554 - 0.9554455445544554 - 0.9554455445544554 - 0.9554455445544554 - 0.9554455445544554 - 0.9554455445544554 - 1.0 - 1.0 - 1.0 GGGtGRT 0.9554455445544554 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9554455445544554 0.9554455445544554 0.9554455445544554 0.9554455445544554 0.9554455445544554 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)YKGILEVTGGR MGYG000000002_00856;MGYG000000301_00189;MGYG000000252_01792;MGYG000000216_02330;MGYG000002298_00361;MGYG000000031_02237;MGYG000001338_02781;MGYG000001496_03147;MGYG000000389_02481;MGYG000004733_01001 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3XYWU@572511|Blautia 0.5 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)YNSVEVPTK MGYG000000133_00993;MGYG000000301_01128 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471150 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 605542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340675 0 0 628696 0 0 0 936069 0 819342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1012036 0 0 0 0 0 -(Carbamidomethyl)YRPQFYLR MGYG000004757_00594;MGYG000000042_01421;MGYG000000408_01653;MGYG000004464_00178;MGYG000000138_00665;MGYG000000385_01364;MGYG000000053_00908;MGYG000001630_01142;MGYG000003643_00595;MGYG000004006_00433;MGYG000004848_00666;MGYG000003353_00058;MGYG000000074_01773;MGYG000003460_01161;MGYG000000215_00564;MGYG000002219_01207;MGYG000001806_01406;MGYG000001925_01419;MGYG000000273_00431;MGYG000004763_01689;MGYG000003681_02037;MGYG000001302.1_00073;MGYG000003202_00129;MGYG000002281_02290;MGYG000001503_00139;MGYG000000357_02040;MGYG000003546_00955;MGYG000001770_01653;MGYG000003992_01709;MGYG000002470_01245;MGYG000003446_00658;MGYG000001552_00984;MGYG000002165_00803;MGYG000001313_00097;MGYG000004629_00424;MGYG000000013_02251;MGYG000003691_01713;MGYG000003542_01415;MGYG000002455_03884;MGYG000003697_01485;MGYG000000348_00283;MGYG000001655_02933;MGYG000000044_01721;MGYG000001360_01239;MGYG000002834_01866;MGYG000002930_00867;MGYG000003152_01866;MGYG000004756_01173;MGYG000000196_03974;MGYG000004588_00463;MGYG000002905_00001;MGYG000001661_02666;MGYG000003374_00521;MGYG000002762_01733;MGYG000001789_00154;MGYG000000054_03933;MGYG000002293_00521;MGYG000000236_01807;MGYG000003701_03123;MGYG000002291_02272;MGYG000000098_02017;MGYG000000170_00073;MGYG000002080_00527;MGYG000004474_01617;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000001346_01533;MGYG000000243_01988;MGYG000001780_03476;MGYG000001562_01075;MGYG000002540_03367;MGYG000001763_00317;MGYG000000254_02569;MGYG000003812_01875;MGYG000003279_00951;MGYG000003497_00215;MGYG000000414_00662;MGYG000002418_00753;MGYG000000117_01463;MGYG000003535_00219;MGYG000000168_03211;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.32142857142857145 976|Bacteroidetes 0.9166666666666666 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9761904761904762 tuf 1.0 - 0.9761904761904762 - 1.0 ko:K02358 0.9761904761904762 - 0.9761904761904762 - 0.9761904761904762 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9761904761904762 - 0.9761904761904762 - 1.0 - 0.9761904761904762 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9761904761904762 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)YVEILNVVK MGYG000000271_02100;MGYG000000489_01027 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamidomethyl)YVVMSAPSKDDTPMFVC(Carbamidomethyl)GVNEK MGYG000000196_00479;MGYG000004479_00217;MGYG000003693_00860;MGYG000004464_00783;MGYG000003312_01022;MGYG000001661_02632;MGYG000002455_02200;MGYG000002478_03999;MGYG000001783_01519;MGYG000001313_02393;MGYG000002549_00455;MGYG000000243_01331;MGYG000000273_02725;MGYG000002281_04045;MGYG000000043_01774;MGYG000004748_00450;MGYG000001345_01069;MGYG000003681_00790;MGYG000002933_02039 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 392825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581766 0 0 0 0 460437 0 0 313698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193945 0 0 0 0 0 0 0 285188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232154 -(Carbamyl)AAASESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1136994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 925080 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)AAATAADKAR MGYG000004733_00775;MGYG000001338_01157;MGYG000000133_00993;MGYG000000301_01128 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4991204 0 0 0 0 0 0 0 0 0 4734591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522778 0 0 0 0 0 0 0 0 0 470067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1377675 0 0 0 0 0 0 0 0 0 1961266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)AAAVNIVPNSTGAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 139539 0 0 0 0 0 0 201601 0 0 0 0 0 0 0 0 0 0 232252 0 0 0 0 0 0 0 0 0 0 0 204124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237542 0 424172 0 0 0 0 0 0 157375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 708181 0 0 0 0 0 0 774803 0 0 0 790040 925780 0 0 0 478129 0 578251 0 0 0 0 0 0 0 489559 0 614992 0 1026640 0 0 0 0 556404 -(Carbamyl)AADDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642195 0 0 0 0 0 0 0 0 0 0 0 916507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375070 0 0 0 0 751065 -(Carbamyl)AADIVLQAAIAAGAPK MGYG000002323_02346;MGYG000000093_03243;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206;MGYG000002534_02768;MGYG000003883_03730 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.8571428571428571 1236|Gammaproteobacteria 1.0 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.8571428571428571 adhE 1.0 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4990357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)AALIDC(Carbamidomethyl)LAPDR MGYG000002515_01045;MGYG000002535_02741;MGYG000002323_01572;MGYG000002494_01366;MGYG000002507_01860;MGYG000002506_00283;MGYG000000107_04278;MGYG000000235_02283;MGYG000003372_01027 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3WWJT@544|Citrobacter 0.3333333333333333 1236|Gammaproteobacteria 1.0 M 1.0 Belongs to the ompA family 0.3333333333333333 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 264487 0 0 0 0 0 0 76673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 580529 0 0 0 0 0 0 652529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376578 0 0 0 0 359151 0 0 199366 0 0 0 0 0 0 260145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317960 0 0 0 0 310381 0 0 166071 0 0 0 0 0 0 171097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)AAPAVVTPIFQNAGK MGYG000001346_01584 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1256@1|root,COG1256@2|Bacteria,4PKVX@976|Bacteroidetes,2G05N@200643|Bacteroidia,4AWF1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 bacterial-type flagellum assembly 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4559138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)ADLKDVEDSNLGLK MGYG000000312_02426;MGYG000003486_02521 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 327128 0 0 0 0 0 0 0 307489 0 0 0 251276 232738 0 0 0 0 0 168307 0 0 0 0 0 295415 0 0 0 0 0 230573 0 0 0 295368 407596 0 0 0 0 0 0 0 0 0 776199 0 0 0 886938 856895 0 0 0 0 0 1292407 0 0 0 0 0 1158256 0 0 0 0 0 1192677 0 0 0 983091 775402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)AEGALSETHSILQR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 543017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564671 0 0 0 0 0 0 0 0 0 0 650714 0 0 0 0 0 0 0 0 0 0 0 0 354127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 696152 0 0 0 0 0 0 0 0 0 0 0 0 369377 0 0 0 0 0 0 0 0 0 0 0 0 0 1262660 0 0 0 0 0 0 0 0 0 0 1061280 0 0 0 0 0 0 0 0 0 0 1103462 0 338386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 323315 0 -(Carbamyl)AIGGVIVDGGK MGYG000002517_01802 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 O-acetylhomoserine 1.0 metY 1.0 - 1.0 2.5.1.49 1.0 ko:K01740 1.0 ko00270,ko01100,map00270,map01100 1.0 - 1.0 R01287,R04859 1.0 RC00020,RC02821,RC02848 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10123944 14223418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)AMVVQHNLTAMNANR MGYG000000404_00502 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA11774|s__UBA11774 sp003507655|m__MGYG000000404 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)AQAHINAGAR MGYG000000251_00555;MGYG000000280_02459;MGYG000003694_01737;MGYG000002974_01418;MGYG000004140_01100;MGYG000001186_01925;MGYG000000484_01691;MGYG000000398_00286;MGYG000001683_01827;MGYG000001748_01525;MGYG000000271_03250;MGYG000004271_00554;MGYG000001319_00348;MGYG000003828_01578;MGYG000000404_00344;MGYG000002517_01026;MGYG000000153_00303;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000140_01181 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.8095238095238095 186801|Clostridia 1.0 G 0.9047619047619048 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8095238095238095 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877738 0 0 0 544619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477472 0 0 0 453505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1794678 0 0 0 1587962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640247 0 0 0 823826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)AQIIAEYGR MGYG000001564_01760;MGYG000000179_05510;MGYG000002946_01744 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,220GG@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 - 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 757454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3668870 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3772603 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)ATEITAYVVK MGYG000004735_01873 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 aconitate hydratase 1.0 ybhJ 1.0 - 1.0 4.2.1.3 1.0 ko:K01681 1.0 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 1.0 M00009,M00010,M00012,M00173,M00740 1.0 R01324,R01325,R01900 1.0 RC00497,RC00498,RC00618 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aconitase,Aconitase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aconitate hydratase. citrate hydro-lyase. Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate.-!-The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate.-!-cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate.-!-Formerly EC 4.2.1.4. citrate = D-threo-isocitrate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Citrate cycle (TCA cycle);Glyoxylate and dicarboxylate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1202837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769026 0 0 0 0 0 0 0 -(Carbamyl)AVVDAGWMTADHQVGQTGK MGYG000002720_01216 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WCFX@538999|Clostridiales incertae sedis 1.0 186801|Clostridia 1.0 C 1.0 PFAM Electron transfer flavoprotein domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3061493 0 0 0 0 0 1419834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)AYLEAWDTYK MGYG000004797_03700 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,2FN8P@200643|Bacteroidia,4AMSQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 COG NOG06391 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4301 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 969117 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)AYLEAWDTYKEGEK MGYG000004797_03700 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,2FN8P@200643|Bacteroidia,4AMSQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 COG NOG06391 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4301 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1351067 0 0 0 0 1368901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95707 0 0 0 0 0 0 0 -(Carbamyl)DVKEEEEFLLR MGYG000000133_00992 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0510@1|root,COG0510@2|Bacteria,1TQW6@1239|Firmicutes,248A0@186801|Clostridia,36UHB@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 M 1.0 Phosphotransferase enzyme family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 APH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 306280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 906648 0 0 0 0 0 0 0 0 0 998471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)EGMGAFLEKR MGYG000002492_00917;MGYG000002670_01219;MGYG000002953_01330;MGYG000002143_01789;MGYG000003185_01503;MGYG000000099_01614;MGYG000001502_02387;MGYG000002926_00641;MGYG000001564_00906;MGYG000003869_00107;MGYG000004271_02656;MGYG000002673_01999;MGYG000002156_02025;MGYG000000271_02750;MGYG000002517_02338;MGYG000000164_00684;MGYG000003694_02682;MGYG000000489_01666;MGYG000003589_00701;MGYG000000356_02284;MGYG000004276_00459;MGYG000004489_00132 domain d__Bacteria 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.3181818181818182 186801|Clostridia 0.9545454545454546 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5454545454545454 crt 0.9545454545454546 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 217372 0 0 0 0 0 0 471824 0 0 0 0 0 308931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853065 0 0 0 0 0 0 1042894 0 0 0 0 0 1049686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)EHILLAR MGYG000000042_01421;MGYG000004464_00178;MGYG000001673_01975;MGYG000004704_00398;MGYG000000089_01901;MGYG000004288_00862;MGYG000002619_00483;MGYG000000412_01546;MGYG000002259_00929;MGYG000002926_00232;MGYG000000099_01234;MGYG000004763_01689;MGYG000003681_02037;MGYG000001384_04567;MGYG000003937_01027;MGYG000002707_01740;MGYG000002994_01317;MGYG000001313_00097;MGYG000003266_00392;MGYG000002455_03884;MGYG000000348_00283;MGYG000001776_00769;MGYG000000044_01721;MGYG000001672_00396;MGYG000002059_00460;MGYG000002685_01157;MGYG000002557_00102;MGYG000000196_03974;MGYG000001008_02651;MGYG000001661_02666;MGYG000001300_00280;MGYG000004769_00437;MGYG000002084_01252;MGYG000000433_00368;MGYG000003022_00748;MGYG000002040_01212;MGYG000002098_01616;MGYG000003266_00955;MGYG000000098_02017;MGYG000001757_01274;MGYG000001299_01777;MGYG000002224_01123;MGYG000002438_02321;MGYG000000163_00957;MGYG000004285_00597;MGYG000001346_01533;MGYG000003073_01160;MGYG000001616_00520;MGYG000003921_01124;MGYG000001238_02207;MGYG000002996_00986;MGYG000002052_00232;MGYG000002418_00753;MGYG000002448_02351;MGYG000000223_03134;MGYG000003352_00730;MGYG000001319_01764;MGYG000004757_00594;MGYG000001365_00649;MGYG000002695_01057;MGYG000000138_00665;MGYG000004769_00412;MGYG000001630_01142;MGYG000002673_02521;MGYG000003022_00735;MGYG000004717_00227;MGYG000000365_00508;MGYG000004276_00122;MGYG000001925_01419;MGYG000000273_00431;MGYG000000867_00556;MGYG000004788_02115;MGYG000000291_00377;MGYG000003202_00129;MGYG000002993_01302;MGYG000000357_02040;MGYG000002953_03321;MGYG000003546_00955;MGYG000000375_01434;MGYG000000022_02283;MGYG000002901_00528;MGYG000003446_00658;MGYG000003899_01642;MGYG000003891_00382;MGYG000002925_00238;MGYG000003428_00555;MGYG000000490_01981;MGYG000003686_02367;MGYG000001356_01661;MGYG000001655_02933;MGYG000003977_00001;MGYG000003166_01350;MGYG000003170_00035;MGYG000002905_00001;MGYG000002972_00178;MGYG000002098_00731;MGYG000002702_01978;MGYG000002912_01340;MGYG000003424_00456;MGYG000001789_00154;MGYG000001567_01738;MGYG000000182_00585;MGYG000003441_00074;MGYG000000236_01807;MGYG000003701_03123;MGYG000000084_02000;MGYG000002291_02272;MGYG000004642_00846;MGYG000000187_02029;MGYG000002641_00069;MGYG000001500_01929;MGYG000003170_00048;MGYG000000445_01370;MGYG000002272_01482;MGYG000004221_01651;MGYG000000243_01988;MGYG000001780_03476;MGYG000001665_01696;MGYG000003504_00096;MGYG000001421_00009;MGYG000001646_01118;MGYG000004047_00605 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.1721311475409836 186801|Clostridia 0.45081967213114754 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9590163934426229 - 1.0 ko:K02358 0.9836065573770492 - 0.9836065573770492 - 0.9836065573770492 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9836065573770492 - 0.9836065573770492 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9836065573770492 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1448548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)EHILLSR MGYG000000080_02058;MGYG000000245_03248;MGYG000001688_04229;MGYG000001654_02237;MGYG000004718_00646;MGYG000004735_00884;MGYG000000280_01200;MGYG000004565_01266;MGYG000001714_01291;MGYG000001760_00949;MGYG000000198_01165;MGYG000004893_00932;MGYG000000392_00966;MGYG000003324_00542;MGYG000002563_00522;MGYG000001507_06245;MGYG000000133_02991;MGYG000000919_01815;MGYG000004879_01608;MGYG000001234_01151;MGYG000001623_00993;MGYG000000466_00679;MGYG000000446_00437;MGYG000002202_00030;MGYG000003208_02857;MGYG000002563_00509;MGYG000003895_00135;MGYG000001619_01314;MGYG000000216_02406;MGYG000002517_00205;MGYG000000034_01346;MGYG000000123_01153;MGYG000004296_01668;MGYG000000277_00173;MGYG000004508_00787;MGYG000001469_02077;MGYG000001431_01181;MGYG000001809_00576;MGYG000001652_01300;MGYG000000127_03982;MGYG000000258_00266;MGYG000002670_00364;MGYG000004502_00031;MGYG000004600_00789;MGYG000001635_01137;MGYG000000139_00697;MGYG000001611_00087;MGYG000000255_02009;MGYG000000404_00531;MGYG000000164_01096;MGYG000000018_00453;MGYG000002234_01026;MGYG000000032_01232;MGYG000001777_01732;MGYG000002105_00002;MGYG000000347_00343;MGYG000000532_02409;MGYG000002136_02858;MGYG000003146_01522;MGYG000002286_02469;MGYG000000262_00030;MGYG000001412_04734;MGYG000002772_01895;MGYG000002492_00344;MGYG000003753_00317;MGYG000001615_01716;MGYG000002854_00111;MGYG000001487_02232;MGYG000000143_00646;MGYG000000016_02519;MGYG000002279_01932;MGYG000000201_03875;MGYG000002485_02622;MGYG000004547_01366;MGYG000003063_00662;MGYG000004893_01944;MGYG000000271_03365;MGYG000000185_02848;MGYG000000230_00429;MGYG000001315_01207;MGYG000001602_02247;MGYG000001508_00032;MGYG000001464_00103;MGYG000001558_01002;MGYG000001400_03001;MGYG000001405_04470;MGYG000001310_01963;MGYG000003273_00234;MGYG000000140_01590;MGYG000001404_04883;MGYG000000323_00619;MGYG000001065_02730;MGYG000002528_01098;MGYG000004302_00459;MGYG000004680_02443;MGYG000002609_01147;MGYG000001436_02249;MGYG000000263_00836;MGYG000000157_01091;MGYG000004789_00520;MGYG000000179_00920;MGYG000000134_02651;MGYG000002839_00878;MGYG000000217_01428;MGYG000000173_00405;MGYG000000177_01044;MGYG000001485_02164;MGYG000002290_01325;MGYG000001531_00906;MGYG000002220_00457;MGYG000002195_01684;MGYG000001607_01045;MGYG000000226_00644;MGYG000001141_02439;MGYG000000024_03409;MGYG000003425_03741;MGYG000000251_00064;MGYG000002444_02629;MGYG000000233_00807;MGYG000000142_00171;MGYG000000121_02189;MGYG000001528_00736;MGYG000004087_00551;MGYG000001439_02427;MGYG000000242_00282;MGYG000004216_00603;MGYG000002417_01244;MGYG000002126_00299;MGYG000000335_01138;MGYG000002854_00124;MGYG000001698_04050;MGYG000004558_00415;MGYG000003074_01359;MGYG000000037_01050;MGYG000002837_02416;MGYG000002997_01472;MGYG000000193_02083;MGYG000002212_00196;MGYG000000249_00026;MGYG000003236_02455;MGYG000000121_03149;MGYG000004799_01385;MGYG000000501_01307;MGYG000004630_01824;MGYG000000045_02616;MGYG000001814_01592;MGYG000003656_01823;MGYG000001432_01745;MGYG000003486_01055;MGYG000001617_01406;MGYG000002596_02296;MGYG000001712_00119;MGYG000003620_01283;MGYG000001007_01315;MGYG000003486_01459;MGYG000001732_00030;MGYG000000206_00901;MGYG000004733_01211 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.13924050632911392 186801|Clostridia 0.740506329113924 J 0.9873417721518988 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9810126582278481 tuf 0.9873417721518988 - 0.8164556962025317 - 0.9936708860759493 ko:K02358 0.930379746835443 - 0.9367088607594937 - 0.9430379746835443 - 0.9936708860759493 - 0.9936708860759493 ko00000,ko03012,ko03029,ko04147 0.930379746835443 - 0.9430379746835443 - 0.9936708860759493 - 0.930379746835443 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 0.9873417721518988 - 0.9936708860759493 - 0.9936708860759493 - 0.9936708860759493 - 0.9936708860759493 - - - - 0.9936708860759493 0.9936708860759493 0.9936708860759493 0.9936708860759493 0.9367088607594937 none 1.0 1001671 0 0 678214 0 1174840 0 0 471197 1373204 962051 1158084 0 996090 1472955 1108713 1067643 0 719873 0 0 1135212 0 480290 1284355 1211184 1165042 0 0 0 0 0 0 0 1168963 0 986595 0 1178516 0 0 1114386 0 423194 0 0 1580158 1652978 1490259 1358007 0 1296186 861342 1143785 1149168 0 1441739 0 0 383063 0 834780 1050537 1172035 1039265 0 0 0 0 0 0 0 1552750 0 1145424 0 1203710 0 0 1441299 0 966861 0 0 909911 1166059 877707 886121 0 1717185 1714857 1341456 1760541 0 622322 0 0 1220484 0 613220 1647433 1409559 1636415 0 0 0 0 0 0 0 1623658 0 950233 0 520874 0 0 1150050 0 645097 0 0 1297321 1150508 930625 921106 0 1024251 1096206 1084879 1389762 0 926238 0 0 475511 0 775985 1065318 1044383 899888 0 0 0 0 0 0 0 1287624 0 1279680 0 1039243 0 0 2280005 0 1602107 0 0 1613781 2258997 1710069 1741105 0 2094640 2396307 1028366 1671132 0 1666911 0 0 908166 0 2014978 1645240 1409960 1777478 0 0 0 0 0 0 0 1905335 0 2068622 0 -(Carbamyl)EHLLLAR MGYG000000408_01653;MGYG000004732_02398;MGYG000000089_01901;MGYG000000362_00956;MGYG000003547_00975;MGYG000002259_00929;MGYG000001754_00089;MGYG000004694_00667;MGYG000003155_00314;MGYG000004763_01689;MGYG000004685_00908;MGYG000001384_04567;MGYG000003937_01027;MGYG000003992_01709;MGYG000002455_03884;MGYG000000348_00283;MGYG000001672_00396;MGYG000002059_00460;MGYG000001008_02651;MGYG000000196_03974;MGYG000004573_00004;MGYG000001434_01407;MGYG000001661_02666;MGYG000001541_00185;MGYG000001300_00280;MGYG000003851_00676;MGYG000004769_00437;MGYG000002084_01252;MGYG000003869_01538;MGYG000002578_00911;MGYG000000433_00368;MGYG000000349_00457;MGYG000002040_01212;MGYG000000054_03933;MGYG000004528_00894;MGYG000002794_01318;MGYG000001606_01669;MGYG000000202_03457;MGYG000003442_01057;MGYG000004474_01617;MGYG000003868_01133;MGYG000001359_01254;MGYG000002224_01123;MGYG000004201_01254;MGYG000000036_01380;MGYG000003410_00864;MGYG000003073_01160;MGYG000001616_00520;MGYG000002052_00232;MGYG000002418_00753;MGYG000000369_00927;MGYG000000223_03134;MGYG000003352_00730;MGYG000001334_00218;MGYG000002447_00587;MGYG000004757_00594;MGYG000001365_00649;MGYG000002116_00788;MGYG000002695_01057;MGYG000001756_00183;MGYG000003819_01356;MGYG000004769_00412;MGYG000000395_01440;MGYG000001524_01606;MGYG000001193_00787;MGYG000004724_00878;MGYG000000802_00776;MGYG000000372_00001;MGYG000000273_00431;MGYG000000291_00377;MGYG000003202_00129;MGYG000002944_02285;MGYG000002281_02290;MGYG000002447_00574;MGYG000002993_01302;MGYG000002953_03321;MGYG000003546_00955;MGYG000000022_02283;MGYG000002470_01245;MGYG000000375_01434;MGYG000002901_00528;MGYG000000090_01714;MGYG000001737_01514;MGYG000003891_00382;MGYG000003428_00555;MGYG000000490_01981;MGYG000003686_02367;MGYG000001784_02227;MGYG000001749_02490;MGYG000002980_01277;MGYG000001779_00600;MGYG000001356_01661;MGYG000000488_00776;MGYG000000479_00469;MGYG000002930_00867;MGYG000004526_00639;MGYG000003166_01350;MGYG000003868_01166;MGYG000001677_00114;MGYG000003170_00035;MGYG000002905_00001;MGYG000001590_00854;MGYG000002098_00731;MGYG000002912_01340;MGYG000002702_01978;MGYG000003424_00456;MGYG000000182_00585;MGYG000003441_00074;MGYG000002143_01659;MGYG000000084_02000;MGYG000002291_02272;MGYG000004642_00846;MGYG000004300_00119;MGYG000001559_00042;MGYG000000945_00137;MGYG000000187_02029;MGYG000003185_01053;MGYG000000420_01950;MGYG000003170_00048;MGYG000000445_01370;MGYG000002272_01482;MGYG000004221_01651;MGYG000001444_01618;MGYG000003516_01606;MGYG000000243_01988;MGYG000001780_03476;MGYG000004657_01190;MGYG000002540_03367;MGYG000000254_02569;MGYG000001646_01118;MGYG000003660_00194;MGYG000002042_00774;MGYG000002970_01555;MGYG000003013_00349;MGYG000003484_00308;MGYG000000117_01463;MGYG000002659_00459;MGYG000000042_01421;MGYG000003096_01037;MGYG000002106_00224;MGYG000004464_00178;MGYG000004704_00398;MGYG000001673_01975;MGYG000000385_01364;MGYG000004288_00862;MGYG000002619_00483;MGYG000000412_01546;MGYG000000930_01271;MGYG000002926_00232;MGYG000002578_00898;MGYG000000099_01234;MGYG000003460_01161;MGYG000003681_02037;MGYG000001739_00819;MGYG000002707_01740;MGYG000003185_01074;MGYG000001444_01634;MGYG000002994_01317;MGYG000002165_00803;MGYG000001313_00097;MGYG000002654_00465;MGYG000003266_00392;MGYG000004119_01204;MGYG000004482_01535;MGYG000001576_02230;MGYG000001824_01594;MGYG000003628_01000;MGYG000001563_01273;MGYG000001776_00769;MGYG000000044_01721;MGYG000003549_00407;MGYG000002685_01157;MGYG000004800_00190;MGYG000002762_01733;MGYG000003022_00748;MGYG000001502_01278;MGYG000002098_01616;MGYG000003266_00955;MGYG000004826_01022;MGYG000000098_02017;MGYG000003274_01474;MGYG000001757_01274;MGYG000001299_01777;MGYG000002950.1_00050;MGYG000002438_02321;MGYG000002556_01332;MGYG000000163_00957;MGYG000000267_01379;MGYG000001346_01533;MGYG000004285_00597;MGYG000000333_00136;MGYG000004196_01067;MGYG000003497_00215;MGYG000002768_00022;MGYG000002057_01066;MGYG000003921_01124;MGYG000001238_02207;MGYG000002996_00986;MGYG000002448_02351;MGYG000004475_00887;MGYG000000168_03211;MGYG000001319_01764;MGYG000001881_00748;MGYG000004847_01222;MGYG000000138_00665;MGYG000001630_01142;MGYG000002673_02521;MGYG000003022_00735;MGYG000003528_02124;MGYG000001516_01186;MGYG000004717_00227;MGYG000004726_01622;MGYG000004276_00122;MGYG000000365_00508;MGYG000001925_01419;MGYG000004788_02115;MGYG000000266_00259;MGYG000001503_00139;MGYG000000449_00614;MGYG000000120_01190;MGYG000003446_00658;MGYG000001552_00984;MGYG000003899_01642;MGYG000000013_02251;MGYG000003583_01411;MGYG000002925_00238;MGYG000001655_02933;MGYG000001991_00383;MGYG000003977_00001;MGYG000003872_01017;MGYG000002972_00178;MGYG000001567_01738;MGYG000001789_00154;MGYG000000236_01807;MGYG000003701_03123;MGYG000003389_01825;MGYG000004694_00680;MGYG000001559_01093;MGYG000002641_00069;MGYG000000733_01034;MGYG000002114_00077;MGYG000001500_01929;MGYG000000370_00784;MGYG000002006_00835;MGYG000000622_01283;MGYG000002720_00092;MGYG000004746_00230;MGYG000001665_01696;MGYG000003504_00096;MGYG000001421_00009;MGYG000002848_00884;MGYG000003001_00359;MGYG000004047_00605;MGYG000000673_00997 life d__Bacteria 0.9961 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.16141732283464566 186801|Clostridia 0.484251968503937 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.952755905511811 - 1.0 ko:K02358 0.984251968503937 - 0.984251968503937 - 0.984251968503937 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.984251968503937 - 0.984251968503937 - 1.0 - 0.9881889763779528 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.984251968503937 none 1.0 946688 0 0 0 0 0 0 0 0 0 780282 0 0 0 0 0 0 807094 0 0 0 0 1186318 0 0 1056596 0 1396189 0 0 0 0 0 0 0 0 335074 0 1119061 0 0 0 0 0 0 0 0 0 1676207 0 0 0 0 0 0 711118 0 0 0 0 990998 0 0 1091439 0 1286885 0 0 0 0 0 0 0 0 1070326 0 573861 0 0 0 0 0 0 0 0 0 910311 0 0 0 0 0 0 825611 0 0 0 0 991480 0 0 620514 0 1540431 0 0 0 0 0 0 0 0 647510 0 415399 0 0 0 0 0 0 0 0 0 1055969 0 0 0 0 0 0 424897 0 0 0 0 614060 0 0 649120 0 834101 0 0 0 0 0 0 0 0 575036 0 900552 0 0 0 0 0 0 0 0 0 1416798 0 0 0 0 0 0 1121405 0 0 0 0 1052090 0 0 932367 0 570259 0 0 0 0 0 0 0 0 1156377 0 -(Carbamyl)EMIFKQMYANGIKDYFVELEQMPDGR MGYG000002438_02512 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,2FX90@200643|Bacteroidia,231YG@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Xylose isomerase-like TIM barrel 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1165754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)ERCESPILIAEDSPLLSR MGYG000002517_02216 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,24AQW@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 response regulator receiver 1.0 cheV 1.0 - 1.0 2.7.13.3 1.0 ko:K03407,ko:K03415 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW,HATPase_c,Hpt,Response_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 histidine kinase. protein kinase (histidine). This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine).-!-A number of histones can act as acceptor. ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 199548 0 0 0 0 0 0 0 0 0 0 0 0 0 148691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242053 0 151471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136859 0 0 0 278446 0 0 0 0 0 0 111421 0 270823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273854 0 0 0 0 0 0 0 0 0 0 333033 0 753483 0 0 0 0 0 0 0 0 0 0 0 0 0 888033 0 0 0 0 0 0 0 0 0 0 725386 781413 0 0 607204 0 0 0 536948 760071 648420 795239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)EVYYC(Carbamidomethyl)GDEDDGHAKK MGYG000000233_01872 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG5263@1|root,COG5263@2|Bacteria,1UY86@1239|Firmicutes,24EH1@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Cell wall-binding repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1228161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)GAGLTGEKDDKYYQSGK MGYG000000179_05046;MGYG000001311_00301 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 192035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 483459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1382425 0 0 0 0 0 0 0 0 0 0 743962 0 -(Carbamyl)GAPEGFVAPVTPGR MGYG000002549_02918;MGYG000002281_02268;MGYG000001345_04706;MGYG000000196_03996;MGYG000000243_01964;MGYG000001346_01512;MGYG000001313_00067;MGYG000001433_02283;MGYG000001378_05020;MGYG000002561_02182;MGYG000002560_00243;MGYG000000054_03865;MGYG000002455_03906;MGYG000000098_01995;MGYG000002478_00792;MGYG000002933_02454;MGYG000001370_01702;MGYG000003312_02984;MGYG000000013_02229 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,2FRZE@200643|Bacteroidia,4AKTM@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs 1.0 rplP 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02878 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 611834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1177359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 578024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3322842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)GFTQDDAHLFVR MGYG000003279_02468;MGYG000000074_00697;MGYG000000003_00538 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,2FMAU@200643|Bacteroidia,22U2K@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1236451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1880747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)GIDKAEIKR MGYG000002291_02272;MGYG000001630_01142;MGYG000000243_01988;MGYG000003691_01713 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 955682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 685640 0 0 0 0 718572 0 0 242523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178603 0 0 0 0 145458 0 0 1068896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1100357 0 0 101603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114073 0 0 0 0 5570750 0 0 1274364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 624081 0 0 0 0 64583 -(Carbamyl)GITINTSHVEYQTANR MGYG000000042_01421;MGYG000004756_01173;MGYG000001415_02515;MGYG000002438_02321;MGYG000004658_01205;MGYG000000053_00908;MGYG000000243_01988;MGYG000000013_02251;MGYG000004006_00433;MGYG000001562_01075;MGYG000000074_01773;MGYG000001789_00154;MGYG000003279_00951;MGYG000000273_00431;MGYG000001655_02933;MGYG000004763_01689;MGYG000002418_00753;MGYG000002291_02272;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000000168_03211 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 0.47619047619047616 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 445466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)GLVGAIEAADAMVK MGYG000000233_02829;MGYG000001504_03126;MGYG000001623_00764;MGYG000001388_01233;MGYG000003372_02282;MGYG000003355_02432;MGYG000003869_00942;MGYG000004087_00692;MGYG000002534_03148;MGYG000000262_00362;MGYG000001550_01963;MGYG000002506_01475;MGYG000002042_00147;MGYG000000099_00883;MGYG000000205_00403;MGYG000002477_02550;MGYG000000198_03144;MGYG000001065_00275;MGYG000002098_00283;MGYG000003131_01143;MGYG000004894_01424;MGYG000002707_01829;MGYG000001564_03645;MGYG000000093_02682;MGYG000002854_00976;MGYG000001622_00878;MGYG000002953_02106 domain d__Bacteria 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 0.3333333333333333 186801|Clostridia 0.7407407407407407 CQ 1.0 BMC 0.3333333333333333 - 0.9259259259259259 - 1.0 - 1.0 - 0.6296296296296297 - 1.0 - 1.0 - 1.0 - 1.0 - 0.6296296296296297 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 216241 0 0 0 0 0 0 0 170715 0 0 0 0 0 0 0 0 0 0 0 685211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 671179 0 0 0 0 0 0 0 189451 0 0 0 0 0 0 0 0 0 0 0 775883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 964307 0 0 0 0 0 0 0 3450102 0 0 0 0 0 0 0 0 0 0 0 124409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2556208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4967544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5418715 0 0 0 0 0 0 0 -(Carbamyl)GQKVNPHGLR MGYG000001365_00964;MGYG000002965_00664;MGYG000000249_01545;MGYG000004250_01651;MGYG000001367_00355;MGYG000001714_01322;MGYG000004517_00981;MGYG000004271_00022;MGYG000000177_02166;MGYG000001602_00386;MGYG000002953_00597;MGYG000002279_01066;MGYG000000187_01752;MGYG000000278_00919;MGYG000004769_00445;MGYG000001754_00745;MGYG000000362_00706;MGYG000000195_02127;MGYG000002619_02380;MGYG000002517_02867;MGYG000000515_01665;MGYG000001300_02209;MGYG000002298_00334;MGYG000002304_02165;MGYG000000071_01873;MGYG000000217_01260;MGYG000002528_01845;MGYG000002057_00239;MGYG000000140_01889;MGYG000001606_00218;MGYG000000198_04893;MGYG000000089_01490;MGYG000001315_01342;MGYG000002969_00164;MGYG000002312_02271;MGYG000000194_02276;MGYG000004680_02465;MGYG000000141_02175;MGYG000000139_02402;MGYG000004735_01595;MGYG000000262_00152;MGYG000003324_00575;MGYG000000334_01214;MGYG000000028_01616;MGYG000004593_00047;MGYG000004699_00276;MGYG000000050_01178;MGYG000000153_02048;MGYG000002105_00235;MGYG000002036_00649;MGYG000002154_01336;MGYG000003311_01156;MGYG000003876_00398;MGYG000000164_02758;MGYG000000022_02034;MGYG000000463_00749;MGYG000003422_00860;MGYG000000077_02604;MGYG000004558_00370;MGYG000001314_01374;MGYG000004317_00970;MGYG000000271_01067;MGYG000004736_00671;MGYG000000364_01346;MGYG000000146_01045;MGYG000000231_02152;MGYG000001576_02395;MGYG000001619_00828;MGYG000001338_02801;MGYG000004087_00388;MGYG000001626_01890;MGYG000004784_00630;MGYG000002966_02569;MGYG000004726_03510;MGYG000000258_00287;MGYG000003465_00837;MGYG000002290_02018;MGYG000000119_00095;MGYG000001191_00912;MGYG000000080_02261;MGYG000000171_01899;MGYG000004718_00068;MGYG000003215_00869;MGYG000002545_01134;MGYG000002276_00874;MGYG000000145_02795;MGYG000003895_00039;MGYG000003581_01705;MGYG000000245_02644;MGYG000000076_02814;MGYG000003147_00986;MGYG000001439_02149;MGYG000002113_00808;MGYG000000251_01825;MGYG000002159_00254;MGYG000002234_01447;MGYG000004681_01723;MGYG000004022_00110;MGYG000000591_02148;MGYG000002659_00451;MGYG000002492_00381;MGYG000001954_02309;MGYG000004296_00395;MGYG000000002_00876;MGYG000000179_04594;MGYG000004642_00857;MGYG000004727_00011;MGYG000000182_00577;MGYG000000099_02395 domain d__Bacteria 1.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae 0.2018348623853211 186801|Clostridia 0.908256880733945 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 0.9908256880733946 rpsC 0.9908256880733946 - 0.981651376146789 - 1.0 ko:K02982 0.9908256880733946 ko03010,map03010 0.9908256880733946 M00178,M00179 0.9908256880733946 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.9908256880733946 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 0.9908256880733946 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.9908256880733946 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)HVIISAPAGNDLK MGYG000000301_01012;MGYG000003695_01114;MGYG000001338_02547;MGYG000000133_02283;MGYG000004785_01017;MGYG000004296_01958;MGYG000000213_00374;MGYG000000002_02120;MGYG000003012_02911;MGYG000000806_01930;MGYG000003821_01266 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 426362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 634166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 612825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)HYAHVDC(Carbamidomethyl)PGHADYVK MGYG000000171_02844;MGYG000000089_01901;MGYG000003547_00975;MGYG000002259_00929;MGYG000004565_01266;MGYG000001714_01291;MGYG000003353_00058;MGYG000000198_01165;MGYG000004893_00932;MGYG000004804_01395;MGYG000002563_00522;MGYG000004763_01689;MGYG000003363_01661;MGYG000001384_04567;MGYG000001234_01151;MGYG000003992_01709;MGYG000002563_00509;MGYG000001619_01314;MGYG000000348_00283;MGYG000001360_01239;MGYG000004296_01668;MGYG000002834_01866;MGYG000003189_01066;MGYG000004508_00787;MGYG000000742_00548;MGYG000001809_00576;MGYG000001008_02651;MGYG000004588_00463;MGYG000004573_00004;MGYG000001434_01407;MGYG000004600_00789;MGYG000003851_00676;MGYG000002578_00911;MGYG000001515_00389;MGYG000000255_02009;MGYG000000404_00531;MGYG000000164_01096;MGYG000000018_00453;MGYG000001606_01669;MGYG000000202_03457;MGYG000002224_01123;MGYG000001692_03322;MGYG000002052_00232;MGYG000002418_00753;MGYG000000223_03134;MGYG000003352_00730;MGYG000000016_02519;MGYG000001756_00183;MGYG000001193_00787;MGYG000004893_01944;MGYG000000074_01773;MGYG000000372_00001;MGYG000000271_03365;MGYG000002535_04656;MGYG000000273_00431;MGYG000000867_00556;MGYG000000410_01314;MGYG000002281_02290;MGYG000001464_00103;MGYG000000022_02283;MGYG000000375_01434;MGYG000002470_01245;MGYG000004302_00459;MGYG000002901_00528;MGYG000004680_02443;MGYG000003891_00382;MGYG000000490_01981;MGYG000001248_00621;MGYG000002839_00878;MGYG000001779_00600;MGYG000001607_01045;MGYG000002930_00867;MGYG000003425_03741;MGYG000002098_00731;MGYG000000142_00171;MGYG000002912_01340;MGYG000000182_00585;MGYG000002291_02272;MGYG000004300_00119;MGYG000004642_00846;MGYG000000170_00073;MGYG000000187_02029;MGYG000001698_04050;MGYG000000445_01370;MGYG000002272_01482;MGYG000000249_00026;MGYG000000243_01988;MGYG000004657_01190;MGYG000000254_02569;MGYG000001646_01118;MGYG000003013_00349;MGYG000003535_00219;MGYG000002659_00459;MGYG000001732_00030;MGYG000000042_01421;MGYG000002106_00224;MGYG000001673_01975;MGYG000004288_00862;MGYG000001654_02237;MGYG000000412_01546;MGYG000004735_00884;MGYG000003460_01161;MGYG000003681_02037;MGYG000001739_00819;MGYG000003184_03610;MGYG000000133_02991;MGYG000000345_02688;MGYG000004879_01608;MGYG000002165_00803;MGYG000002202_00030;MGYG000001313_00097;MGYG000002654_00465;MGYG000004119_01204;MGYG000001776_00769;MGYG000000044_01721;MGYG000000034_01346;MGYG000001469_02077;MGYG000001431_01181;MGYG000003152_01866;MGYG000002685_01157;MGYG000003374_00521;MGYG000004502_00031;MGYG000000139_00697;MGYG000002762_01733;MGYG000002098_01616;MGYG000004826_01022;MGYG000001757_01274;MGYG000000032_01232;MGYG000001777_01732;MGYG000002105_00002;MGYG000002950.1_00050;MGYG000000347_00343;MGYG000001346_01533;MGYG000004285_00597;MGYG000002772_01895;MGYG000002492_00344;MGYG000000414_00662;MGYG000000168_03211;MGYG000000143_00646;MGYG000002279_01932;MGYG000000138_00665;MGYG000000201_03875;MGYG000000053_00908;MGYG000002603_01782;MGYG000002485_02622;MGYG000004547_01366;MGYG000004006_00433;MGYG000004717_00227;MGYG000000365_00508;MGYG000001602_02247;MGYG000001503_00139;MGYG000000120_01190;MGYG000000140_01590;MGYG000001065_02730;MGYG000001436_02249;MGYG000000263_00836;MGYG000003899_01642;MGYG000000013_02251;MGYG000003583_01411;MGYG000002925_00238;MGYG000000177_01044;MGYG000001485_02164;MGYG000002220_00457;MGYG000001531_00906;MGYG000001991_00383;MGYG000003465_01528;MGYG000004756_01173;MGYG000000024_03409;MGYG000002972_00178;MGYG000000121_02189;MGYG000001567_01738;MGYG000001439_02427;MGYG000000242_00282;MGYG000002417_01244;MGYG000002641_00069;MGYG000000733_01034;MGYG000004558_00415;MGYG000003074_01359;MGYG000001515_00877;MGYG000004658_01205;MGYG000000622_01283;MGYG000003236_02455;MGYG000001665_01696;MGYG000004630_01824;MGYG000003504_00096;MGYG000001617_01406;MGYG000003620_01283;MGYG000001007_01315;MGYG000000408_01653;MGYG000001688_04229;MGYG000004718_00646;MGYG000000280_01200;MGYG000003189_00640;MGYG000004694_00667;MGYG000003324_00542;MGYG000003155_00314;MGYG000002219_01207;MGYG000001507_06245;MGYG000004685_00908;MGYG000001302.1_00073;MGYG000000919_01815;MGYG000001623_00993;MGYG000003142_01879;MGYG000003895_00135;MGYG000002455_03884;MGYG000001672_00396;MGYG000003142_01865;MGYG000000127_03982;MGYG000000196_03974;MGYG000001713_03599;MGYG000001661_02666;MGYG000000258_00266;MGYG000002670_00364;MGYG000001541_00185;MGYG000001300_00280;MGYG000004769_00437;MGYG000001611_00087;MGYG000000433_00368;MGYG000000371_01541;MGYG000000349_00457;MGYG000002040_01212;MGYG000000054_03933;MGYG000004528_00894;MGYG000004474_01617;MGYG000004804_00945;MGYG000003868_01133;MGYG000004722_01495;MGYG000000532_02409;MGYG000000036_01380;MGYG000003410_00864;MGYG000001248_01383;MGYG000002286_02469;MGYG000003812_01875;MGYG000001412_04734;MGYG000003073_01160;MGYG000002937_00892;MGYG000003753_00317;MGYG000002447_00587;MGYG000001365_00649;MGYG000001615_01716;MGYG000002854_00111;MGYG000004769_00412;MGYG000001524_01606;MGYG000003643_00595;MGYG000004724_00878;MGYG000000802_00776;MGYG000000215_00564;MGYG000002515_03208;MGYG000000291_00377;MGYG000003202_00129;MGYG000001508_00032;MGYG000002447_00574;MGYG000002506_02966;MGYG000001310_01963;MGYG000001404_04883;MGYG000003546_00955;MGYG000002528_01098;MGYG000003691_01713;MGYG000000157_01091;MGYG000003394_01668;MGYG000001749_02490;MGYG000000488_00776;MGYG000002195_01684;MGYG000004499_02319;MGYG000003166_01350;MGYG000003868_01166;MGYG000001677_00114;MGYG000003170_00035;MGYG000002905_00001;MGYG000000251_00064;MGYG000000233_00807;MGYG000002514_01953;MGYG000002702_01978;MGYG000003424_00456;MGYG000001528_00736;MGYG000003441_00074;MGYG000002126_00299;MGYG000001559_00042;MGYG000000945_00137;MGYG000002854_00124;MGYG000003185_01053;MGYG000003170_00048;MGYG000004221_01651;MGYG000002212_00196;MGYG000003516_01606;MGYG000004799_01385;MGYG000001780_03476;MGYG000002540_03367;MGYG000001814_01592;MGYG000003656_01823;MGYG000003486_01055;MGYG000003660_00194;MGYG000003514_00785;MGYG000002970_01555;MGYG000001712_00119;MGYG000000117_01463;MGYG000000206_00901;MGYG000004733_01211;MGYG000004464_00178;MGYG000000385_01364;MGYG000000245_03248;MGYG000002619_00483;MGYG000000930_01271;MGYG000002578_00898;MGYG000000392_00966;MGYG000001470_03722;MGYG000001806_01406;MGYG000003185_01074;MGYG000001770_01653;MGYG000000446_00437;MGYG000002994_01317;MGYG000003208_02857;MGYG000004629_00424;MGYG000003542_01415;MGYG000003266_00392;MGYG000000216_02406;MGYG000002364_00543;MGYG000001563_01273;MGYG000002515_03657;MGYG000002517_00205;MGYG000003549_00407;MGYG000001652_01300;MGYG000002557_00102;MGYG000004800_00190;MGYG000001338_03373;MGYG000003022_00748;MGYG000002293_00521;MGYG000000098_02017;MGYG000003274_01474;MGYG000002234_01026;MGYG000002080_00527;MGYG000001299_01777;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000000267_01379;MGYG000000333_00136;MGYG000001562_01075;MGYG000001763_00317;MGYG000000262_00030;MGYG000003279_00951;MGYG000004754_01565;MGYG000002768_00022;MGYG000003921_01124;MGYG000002506_03686;MGYG000001319_01764;MGYG000001881_00748;MGYG000004847_01222;MGYG000001630_01142;MGYG000003063_00662;MGYG000003022_00735;MGYG000003528_02124;MGYG000001925_01419;MGYG000001315_01207;MGYG000000266_00259;MGYG000000449_00614;MGYG000001405_04470;MGYG000003273_00234;MGYG000003446_00658;MGYG000001552_00984;MGYG000002609_01147;MGYG000002514_02415;MGYG000001525_00035;MGYG000000179_00920;MGYG000003697_01485;MGYG000002507_00346;MGYG000000217_01428;MGYG000001655_02933;MGYG000000173_00405;MGYG000002290_01325;MGYG000001141_02439;MGYG000003977_00001;MGYG000003872_01017;MGYG000001789_00154;MGYG000000236_01807;MGYG000004087_00551;MGYG000003701_03123;MGYG000003389_01825;MGYG000004694_00680;MGYG000004216_00603;MGYG000001559_01093;MGYG000000212_03313;MGYG000002830_01189;MGYG000000037_01050;MGYG000002837_02416;MGYG000000193_02083;MGYG000004746_00230;MGYG000000501_01307;MGYG000001421_00009;MGYG000000405_00711;MGYG000001432_01745;MGYG000003001_00359;MGYG000002596_02296;MGYG000004047_00605;MGYG000000673_00997 life d__Bacteria 0.9975 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.09620253164556962 186801|Clostridia 0.47848101265822784 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9645569620253165 tuf 1.0 - 0.9215189873417722 - 1.0 ko:K02358 0.9924050632911392 - 0.9924050632911392 - 0.9924050632911392 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9924050632911392 - 0.9924050632911392 - 1.0 - 0.9493670886075949 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9924050632911392 none 1.0 0 1017916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 547336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 655742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)ICSDNAVFGQPEVGLGITPGFGGTQR MGYG000001315_01870;MGYG000000195_01573;MGYG000001809_02346;MGYG000003937_01091;MGYG000001300_00295;MGYG000003899_01136;MGYG000000022_01324;MGYG000004679_00524;MGYG000003166_01334;MGYG000002274_00044;MGYG000002545_00548;MGYG000004039_00584;MGYG000000217_01338;MGYG000000039_00171;MGYG000002040_01715;MGYG000001255_01114 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 0.75 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.75 thlA 0.75 - 1.0 2.3.1.9 0.75 ko:K00626 0.75 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 0.75 M00088,M00095,M00373,M00374,M00375 0.75 R00238,R01177 0.75 RC00004,RC00326 0.75 ko00000,ko00001,ko00002,ko01000,ko04147 0.75 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 0.75 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 0.75 0.75 0.75 0.75 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3798951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)ICVLEKEEDVC(Carbamidomethyl)C(Carbamidomethyl)GTSK MGYG000000205_00110;MGYG000000038_01495;MGYG000000255_01681 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 1.0 186801|Clostridia 1.0 S 1.0 BFD-like [2Fe-2S] binding domain 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 1970668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 970576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)ILVTLLHEMQK MGYG000004525_00228;MGYG000002953_03277;MGYG000002670_01511;MGYG000002727_00924;MGYG000004769_00635;MGYG000003215_01534;MGYG000001356_02661;MGYG000002156_00131;MGYG000002720_01849;MGYG000000164_00683;MGYG000001814_02499;MGYG000001616_02334;MGYG000001637_02269;MGYG000001500_00694;MGYG000004628_02379;MGYG000001711_01126;MGYG000000153_01463;MGYG000003694_00877;MGYG000003589_00853;MGYG000002492_00657;MGYG000002099_02958;MGYG000000204_00804;MGYG000000997_00552;MGYG000000077_02464;MGYG000002926_00108;MGYG000002143_01933;MGYG000000280_01473;MGYG000002485_00796;MGYG000003074_00590;MGYG000002673_02531;MGYG000000389_02151;MGYG000002945_00734;MGYG000000262_02231;MGYG000001793_01810;MGYG000004271_00231;MGYG000000245_02019;MGYG000000271_02104;MGYG000002517_00540;MGYG000004475_01257;MGYG000001315_01871 domain d__Bacteria 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.325 186801|Clostridia 0.925 I 1.0 Belongs to the thiolase family 0.55 thlA 0.925 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2885778 0 -(Carbamyl)INHTPDDACVTTFMTPVEK MGYG000001300_00424 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3WGWJ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4863886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1637147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)IQEKIDWMMNIK MGYG000001313_00346 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 628341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)IVTDGCVVSYIHGGGR MGYG000001315_00797 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1963218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)LAAIIPIDTAVK MGYG000000182_01809 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Mitsuokella|s__Mitsuokella sp003458855|m__MGYG000000182 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,4H2K7@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1901992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)LEHTIANLDNVVENTTSAESR MGYG000002552_01183;MGYG000004317_00093;MGYG000000398_01963 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4586826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)LVAHGVEEVK MGYG000003452_00041 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium ruminantium|m__MGYG000003452 1.0 COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CZ1D@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3528315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)MLAHLLK MGYG000000038_02185;MGYG000001311_02933;MGYG000003582_01256;MGYG000001558_01857;MGYG000002619_02023;MGYG000003374_01118;MGYG000000771_01164;MGYG000001412_01313;MGYG000000272_02321;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000001763_00396;MGYG000000223_00996;MGYG000001711_02099;MGYG000004732_01055;MGYG000001255_00370;MGYG000001482_02362;MGYG000001496_01122;MGYG000004493_00097;MGYG000000002_02120;MGYG000002194_02222;MGYG000004271_00554;MGYG000002966_00075;MGYG000004317_00142;MGYG000000233_00345;MGYG000001577_01888;MGYG000000174_02692;MGYG000001652_01009;MGYG000000077_00219;MGYG000000127_04855;MGYG000002993_00787;MGYG000002945_00682;MGYG000000229_00395;MGYG000004610_00503;MGYG000002098_00013;MGYG000002212_00259;MGYG000004826_01307;MGYG000001606_02632;MGYG000000213_00374;MGYG000003465_00706;MGYG000001542_01437;MGYG000002517_01026;MGYG000004707_01697;MGYG000000212_01474;MGYG000002126_00535;MGYG000000515_01608;MGYG000001338_02547;MGYG000003074_01265;MGYG000001493_05257;MGYG000004757_01889;MGYG000002141_01131;MGYG000000217_00275;MGYG000001439_00571;MGYG000000280_02459;MGYG000000249_01352;MGYG000003695_01114;MGYG000004691_00618;MGYG000002641_00563;MGYG000000193_03247;MGYG000000140_01181;MGYG000000080_03115;MGYG000002279_00557;MGYG000004799_00704;MGYG000001814_01253;MGYG000003656_01296;MGYG000000242_02076;MGYG000002492_01379;MGYG000000198_04065;MGYG000001334_01647;MGYG000001199_01005;MGYG000001658_00407;MGYG000001688_03910;MGYG000000278_03657;MGYG000001319_00348;MGYG000000495_01130;MGYG000001303_01883;MGYG000000187_02264;MGYG000003504_01686;MGYG000000371_00136;MGYG000004519_00423;MGYG000000097_00328;MGYG000001525_01747;MGYG000000615_00488;MGYG000001423_00991;MGYG000001157_00577;MGYG000000171_00850;MGYG000000195_01135;MGYG000001008_00728;MGYG000000271_03250;MGYG000000562_01218;MGYG000000022_00437;MGYG000000133_02283;MGYG000002298_02410;MGYG000000489_00503;MGYG000004600_00849;MGYG000000399_00360;MGYG000003694_01737;MGYG000001607_01815;MGYG000000230_01325;MGYG000003355_00996;MGYG000000484_01691;MGYG000001710_00672;MGYG000003001_00320;MGYG000000205_02269;MGYG000000145_03615;MGYG000002528_00367;MGYG000004140_01100;MGYG000002188_01071;MGYG000002286_00420;MGYG000000164_00800;MGYG000001748_01525;MGYG000001714_01796;MGYG000002946_02881;MGYG000000150_00838;MGYG000000404_00344;MGYG000004815_01345;MGYG000000141_02825;MGYG000003552_01242;MGYG000003702_00925;MGYG000001781_01334;MGYG000001542_02015;MGYG000002304_00547;MGYG000004740_01468;MGYG000000045_02136;MGYG000000162_00065;MGYG000000089_01653;MGYG000004296_01958;MGYG000002155_00766;MGYG000000179_02084;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000001299_00204;MGYG000000251_00555;MGYG000002992_00164;MGYG000002974_01418;MGYG000002997_01277;MGYG000001237_01808;MGYG000004785_01017;MGYG000002025_02240;MGYG000002963_04095;MGYG000000463_00862;MGYG000001602_01805;MGYG000002052_00078;MGYG000001970_02077;MGYG000004246_01300;MGYG000000153_00303;MGYG000001315_01699;MGYG000001627_00130;MGYG000001469_02299;MGYG000003409_01628;MGYG000003891_00096;MGYG000001310_02090;MGYG000002445_01920;MGYG000000325_00586;MGYG000000909_00644;MGYG000002234_00398;MGYG000003431_01105;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000004809_00788;MGYG000003450_00202;MGYG000003701_01708;MGYG000001954_02254;MGYG000002638_00362;MGYG000000215_01375;MGYG000001065_01088;MGYG000004810_01402;MGYG000000100_02166;MGYG000002131_02428;MGYG000003335_00316;MGYG000000084_01085;MGYG000001300_02008;MGYG000004866_01631;MGYG000003937_01177;MGYG000000252_01324;MGYG000000365_00999;MGYG000000301_01012;MGYG000004722_00591;MGYG000001186_01925;MGYG000004087_02290;MGYG000000312_01508;MGYG000000204_00778;MGYG000003013_01053;MGYG000002857_01020;MGYG000004288_00401;MGYG000000175_00767;MGYG000004714_00143;MGYG000003133_02653;MGYG000000281_02732;MGYG000001619_01736;MGYG000000398_00286;MGYG000001683_01827;MGYG000001421_02311;MGYG000004789_01485;MGYG000003812_01036;MGYG000004735_01946;MGYG000003503_01071;MGYG000004809_00408;MGYG000004593_01977 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.20398009950248755 186801|Clostridia 0.7711442786069652 C 0.5870646766169154 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.47761194029850745 gap 0.9552238805970149 - 0.9154228855721394 1.2.1.12 0.9850746268656716 ko:K00134 0.9850746268656716 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9850746268656716 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9850746268656716 R01061 0.9850746268656716 RC00149 0.9850746268656716 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9850746268656716 - 0.9950248756218906 - 1.0 - 0.9850746268656716 Gp_dh_C,Gp_dh_N 0.9850746268656716 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9850746268656716 0.9850746268656716 0.9850746268656716 0.9850746268656716 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9850746268656716 none 1.0 0 523574 0 0 0 587404 0 724559 0 0 531273 0 0 0 0 512826 0 0 0 0 0 487103 0 206307 0 0 0 0 0 0 218098 0 0 0 0 0 0 0 0 737473 0 0 0 324018 0 293019 0 0 491229 0 0 0 0 224458 0 0 0 0 0 209351 0 388567 0 0 0 0 0 0 592476 0 0 0 0 0 0 0 0 752396 0 0 0 393037 0 470008 0 0 341303 0 0 0 0 595050 0 0 0 0 0 598546 0 204260 0 0 0 0 0 0 196385 0 0 0 0 0 0 0 0 439772 0 0 0 285107 0 385070 0 0 387223 0 0 0 0 289846 0 0 0 0 0 313215 0 0 0 0 0 0 0 0 818827 0 0 0 0 0 0 0 0 806772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 792599 0 669578 0 0 367245 533391 0 640762 691985 591827 0 592139 295684 0 1052401 777319 0 0 0 416376 393229 0 629033 0 324400 0 0 0 681534 0 0 524943 687358 558413 0 441375 443762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81691 0 0 0 0 0 0 0 511771 0 0 0 0 0 0 0 0 0 0 0 0 0 291502 0 0 109035 0 0 165602 721119 0 0 0 596424 0 720687 0 0 993036 0 0 0 0 660802 0 0 0 0 0 0 0 0 745505 0 0 0 0 0 0 0 850361 395928 0 757013 0 0 0 240754 0 0 388027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 452465 1015046 0 1325887 0 0 0 1040931 0 1958577 1833211 1420667 0 953520 1112857 0 979166 1654413 0 1388060 0 1135710 866100 0 1191710 1624915 1354030 0 0 0 2133337 0 0 987641 1437378 1601826 0 3049647 1912001 -(Carbamyl)MYAIIATGGK MGYG000000018_00160;MGYG000002945_00146;MGYG000004140_00663;MGYG000001065_00185;MGYG000001707_00190;MGYG000002963_04167;MGYG000000095_03449;MGYG000002966_01844;MGYG000000141_00422;MGYG000000562_01328;MGYG000001607_00044;MGYG000002609_00091;MGYG000004879_01688;MGYG000002756_01375;MGYG000001543_03463;MGYG000000356_00131;MGYG000001564_03151;MGYG000000136_00836;MGYG000001338_01924;MGYG000004762_02308;MGYG000001687_00102;MGYG000002025_02389;MGYG000000249_01814;MGYG000001688_02554;MGYG000002098_01393;MGYG000001714_01831;MGYG000002445_00346;MGYG000000268_00142;MGYG000000233_01434;MGYG000001602_02315;MGYG000002552_00424;MGYG000000312_00330;MGYG000003684_00524;MGYG000000206_00602;MGYG000000038_02046;MGYG000000171_00402;MGYG000000123_04902;MGYG000004719_01440;MGYG000004735_00428;MGYG000001652_01261;MGYG000001367_01066;MGYG000001496_00976;MGYG000001319_02167;MGYG000004781_02718;MGYG000000262_02346;MGYG000001619_00163;MGYG000000271_00118;MGYG000000087_01675;MGYG000001219_01271;MGYG000002312_01467;MGYG000000164_00669;MGYG000000179_02644;MGYG000004740_00778;MGYG000004630_00782;MGYG000002772_00321;MGYG000004785_01646;MGYG000002145_00595;MGYG000000119_00390;MGYG000000213_03472;MGYG000002835_02344;MGYG000000245_00171;MGYG000000076_01152;MGYG000000080_01568;MGYG000001617_02393;MGYG000003425_04016;MGYG000001814_00334;MGYG000004039_00665;MGYG000001698_00228;MGYG000002247_01198;MGYG000004747_01719;MGYG000000378_00991;MGYG000000205_02464;MGYG000002212_02935;MGYG000002286_00609;MGYG000000193_01220;MGYG000001315_03087;MGYG000000489_00337;MGYG000002670_00617;MGYG000000154_00623;MGYG000001531_02377;MGYG000002992_00061;MGYG000000252_00071;MGYG000000140_00813;MGYG000000806_02097;MGYG000000146_00229;MGYG000002492_01534;MGYG000000187_02418;MGYG000000389_01071;MGYG000002528_02697;MGYG000000142_02633;MGYG000003694_00194;MGYG000004271_00287;MGYG000001493_00431;MGYG000001027_01084;MGYG000000216_01562;MGYG000001379_00307;MGYG000000028_00974;MGYG000001658_02153;MGYG000002279_00674;MGYG000004087_00797;MGYG000000217_01572;MGYG000002517_01481;MGYG000000077_02303;MGYG000000251_01966;MGYG000001310_01505;MGYG000000280_00589;MGYG000001615_00216;MGYG000000194_02994;MGYG000002216_01104;MGYG000002136_00755;MGYG000002170_01844;MGYG000001689_02530;MGYG000000118_00921;MGYG000000359_00548;MGYG000001637_01560;MGYG000000198_03199;MGYG000002234_01697;MGYG000004296_00312 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia 0.2796610169491525 186801|Clostridia 0.9830508474576272 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 - 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)NVALDIK MGYG000002274_00818;MGYG000003899_00639;MGYG000000039_01710;MGYG000001255_02108;MGYG000001300_02189;MGYG000002059_00486;MGYG000004866_02020;MGYG000000195_02108;MGYG000000022_02015;MGYG000002619_02361;MGYG000003166_00784;MGYG000002272_00476;MGYG000000084_01028;MGYG000001627_01338;MGYG000003921_00369;MGYG000000573_01503;MGYG000003937_00241;MGYG000001157_00691 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3WJ08@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 - 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2711393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)SAAELNEELVAAKK MGYG000000038_01584;MGYG000000213_00206;MGYG000000184_01180;MGYG000002945_02576;MGYG000002845_00986;MGYG000001607_01093;MGYG000004733_00976;MGYG000000206_01042;MGYG000001496_03128;MGYG000001748_00602;MGYG000001710_03003;MGYG000001338_02799;MGYG000000200_01105;MGYG000002966_02567;MGYG000000002_00874;MGYG000001698_02694;MGYG000000118_00226;MGYG000000133_00053;MGYG000000301_00168;MGYG000002279_01064 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3Y0MW@572511|Blautia 0.45 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uL29 family 1.0 rpmC 1.0 - 1.0 - 1.0 ko:K02904 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L29 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 983980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)SFDSIDNAPEEKER MGYG000000042_01421;MGYG000004756_01173;MGYG000000196_03974;MGYG000002905_00001;MGYG000000138_00665;MGYG000001661_02666;MGYG000000053_00908;MGYG000004006_00433;MGYG000002762_01733;MGYG000000074_01773;MGYG000001789_00154;MGYG000000273_00431;MGYG000000054_03933;MGYG000000236_01807;MGYG000003701_03123;MGYG000000098_02017;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000001503_00139;MGYG000002281_02290;MGYG000004474_01617;MGYG000003546_00955;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000003446_00658;MGYG000001552_00984;MGYG000001346_01533;MGYG000000243_01988;MGYG000000013_02251;MGYG000001562_01075;MGYG000000348_00283;MGYG000003279_00951;MGYG000000414_00662;MGYG000001655_02933;MGYG000000044_01721;MGYG000002418_00753;MGYG000000117_01463;MGYG000000168_03211 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 821538 0 0 0 0 0 0 0 484071 0 0 724996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690728 0 0 0 0 750945 0 0 458949 0 0 0 0 0 0 0 689308 0 0 390918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342265 0 0 0 0 300620 0 0 473271 0 0 0 0 0 0 0 355978 0 0 406133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326197 0 0 0 0 0 0 0 188292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319441 0 0 0 0 0 0 0 738989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 491247 -(Carbamyl)TCAVSGSGNVAIYAIEK MGYG000002517_02750 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 L 1.0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site 1.0 mfd 1.0 - 1.0 - 1.0 ko:K03723 1.0 ko03420,map03420 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03400 1.0 - 1.0 - 1.0 - 1.0 CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF,UB2H 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Nucleotide excision repair 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1356880 0 0 0 0 0 0 0 0 0 0 0 0 0 1688679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 673971 0 0 0 0 842775 -(Carbamyl)VAVSALDAAK MGYG000003937_01241 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3WKKU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)VFDIAIHGGK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carbamyl)VVILTGGPDKK MGYG000004271_02656;MGYG000000271_02750;MGYG000000404_01534;MGYG000002517_02338;MGYG000000489_01666;MGYG000000076_01479 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,3NGQJ@46205|Pseudobutyrivibrio 0.6666666666666666 186801|Clostridia 1.0 I 1.0 Enoyl-CoA hydratase/isomerase 0.6666666666666666 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 444541 0 0 0 0 0 0 0 0 320506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135079 0 0 0 0 0 0 0 0 906499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1267488 0 0 0 0 0 0 0 0 1125857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)AGVTADSIAK MGYG000002720_01849;MGYG000004487_00561 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,2N6SP@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4445872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)ALC(Carbamidomethyl)DTLEGDER MGYG000002223_00163;MGYG000001255_00186;MGYG000002105_01626;MGYG000001300_01405;MGYG000000022_01398 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3WGUG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)AVGAEVAKR MGYG000000182_00567 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Mitsuokella|s__Mitsuokella sp003458855|m__MGYG000000182 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4H4PJ@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 84146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)GIDGHDAASIKR MGYG000002506_02537 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,3XMMK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate 1.0 tktA 1.0 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,ic_1306.c2990 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 1899373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1230439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2190546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)GVKFDIAKPGESVR MGYG000001315_00847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 28HF7@1|root,2Z7RC@2|Bacteria,1TQET@1239|Firmicutes,249YW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Glycine sarcosine betaine reductase complex, protein B, alpha and beta subunits 1.0 grdE 1.0 - 1.0 1.21.4.2 1.0 ko:K10671 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 197114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635037 0 0 0 0 677369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242270 0 0 0 0 209127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)GVWVFC(Carbamidomethyl)EQR MGYG000002105_00077;MGYG000002610_00221;MGYG000003166_01338;MGYG000000195_01569;MGYG000004487_01101;MGYG000003291_01730;MGYG000002794_00291;MGYG000000022_01320;MGYG000002707_00928;MGYG000001500_03165;MGYG000001824_01146;MGYG000000099_01610;MGYG000002059_01404;MGYG000002224_01329;MGYG000003937_01087;MGYG000004866_01546;MGYG000002651_00003;MGYG000000127_00940;MGYG000002040_01719;MGYG000001761_00373;MGYG000001157_00997;MGYG000003869_00111;MGYG000002619_02235;MGYG000000090_01517;MGYG000001300_00291;MGYG000004732_01392;MGYG000002287_01182;MGYG000002156_02067;MGYG000003899_01132;MGYG000001356_00011;MGYG000002223_00611;MGYG000001255_01110;MGYG000002287_00701;MGYG000004475_01038;MGYG000002720_01216;MGYG000002274_00049;MGYG000003770_01063 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 0.6216216216216216 186801|Clostridia 0.918918918918919 C 1.0 Electron transfer flavoprotein FAD-binding domain 0.6216216216216216 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 0.6216216216216216 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 566147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 602456 0 0 0 0 638166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)IATELYLKR MGYG000002281_04459;MGYG000004564_00976;MGYG000002807_01339;MGYG000001378_04147;MGYG000003460_00457;MGYG000001780_00270;MGYG000001346_00851;MGYG000003374_01159;MGYG000001164_00399;MGYG000001313_03155;MGYG000001630_01414;MGYG000004699_00382;MGYG000002293_00782;MGYG000003697_00358;MGYG000001991_00556;MGYG000002108_00545;MGYG000004528_00573;MGYG000002935_02197;MGYG000001661_02119;MGYG000001056_00806;MGYG000003794_01885;MGYG000001789_00911;MGYG000000243_00072;MGYG000003521_00114;MGYG000000174_03370;MGYG000004876_01422;MGYG000000707_01912;MGYG000000196_02256;MGYG000001345_03306;MGYG000001489_02767;MGYG000000224_01316;MGYG000003423_01801;MGYG000003351_02552;MGYG000003241_00495;MGYG000003493_02326;MGYG000004561_00777;MGYG000003116_01995;MGYG000004495_00225;MGYG000000054_03589;MGYG000001447_00778;MGYG000004758_02044;MGYG000001925_01382;MGYG000004717_00453;MGYG000002834_01489 domain d__Bacteria 1.0 COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,2FMXC@200643|Bacteroidia,4ANTX@815|Bacteroidaceae 0.38636363636363635 976|Bacteroidetes 0.8181818181818182 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family 1.0 lysS 1.0 - 1.0 6.1.1.6 1.0 ko:K04567 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03658 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DUF4332,tRNA-synt_2,tRNA_anti-codon 0.8181818181818182 - 1.0 - 1.0 - 1.0 - 1.0 lysine--tRNA ligase. lysyl-tRNA synthetase. - ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 904126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)IAVDNGGK MGYG000000125_03124 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium_B|s__Clostridium_B tyrobutyricum|m__MGYG000000125 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,36EQT@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1813397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)LLAELDENGNTK MGYG000002478_00469;MGYG000000243_00698 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia,4AK9A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 peptidyl-prolyl cis-trans isomerase (trigger factor) 1.0 tig 1.0 - 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)QGAC(Carbamidomethyl)FSDGTPVTAK MGYG000000233_01508 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,36WU1@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 Extracellular solute-binding protein, family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2010619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)QINDAITADIFEHVK MGYG000001255_00900 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_F|m__MGYG000001255 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)SAWVEYDGNYYFVNSAGAK MGYG000000255_01008 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3465963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2263093 0 0 0 0 0 0 0 1824957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Carboxymethyl)YVGFGEENQVTADDEAGTITVK MGYG000000562_01218 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp000437735|m__MGYG000000562 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,25VFF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 881522 0 892057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(CarboxymethylDMAP)TDIPENIK MGYG000001461_00430;MGYG000001489_02640 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,2FMRC@200643|Bacteroidia,4AMR2@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 173826 261211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467523 0 0 0 0 0 0 293488 0 0 0 0 0 0 0 0 0 462563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 97820 0 0 0 0 0 319596 0 0 0 0 0 0 529592 0 0 0 0 0 0 0 0 0 616804 0 0 0 0 559487 0 0 0 0 0 0 0 0 0 0 0 0 335359 0 0 500501 0 425005 314436 0 0 0 517985 0 0 0 0 0 0 0 0 0 728744 0 0 0 810074 471034 0 0 0 0 0 0 0 0 0 896017 0 0 1009947 0 0 621041 0 1027293 653367 688451 0 0 824700 0 0 0 0 0 0 0 844246 0 17250335 0 0 0 26202256 20575673 0 0 0 0 0 0 0 0 0 20456502 0 0 25063271 0 0 16291940 0 26070832 19010902 20361243 0 0 18949183 0 0 0 0 0 0 0 25625906 0 -(CarboxymethylDMAP)VQDLEDEVAGLSTR MGYG000000243_01609;MGYG000002171_00452;MGYG000002478_03805 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,2FPGP@200643|Bacteroidia,4ANFP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Zinc ribbon domain protein 1.0 - 1.0 - 1.0 - 1.0 ko:K07164 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 zf-RING_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 439877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Cytopiloyne+water)ADDAAGLTISEK MGYG000000489_01309;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000002492_03078;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 887144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1607852 1374321 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Cytopiloyne+water)AEMAATC(Carbamidomethyl)TDPVR MGYG000000262_02730 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 152221 0 0 0 0 0 0 0 0 0 0 0 0 0 431627 0 283631 0 0 0 0 0 0 0 0 0 0 0 0 167497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 601454 0 0 0 0 0 0 0 0 686758 0 0 0 1385058 0 0 0 0 0 0 0 0 0 472262 0 1051358 0 519227 0 0 0 0 0 0 0 0 0 0 2176154 0 0 0 0 0 0 0 0 0 0 0 0 247097 0 0 0 0 0 0 0 0 0 1044857 0 590089 0 1007911 0 0 0 0 0 0 0 0 0 0 872813 0 0 0 0 0 0 0 0 804111 0 0 0 891520 0 0 0 0 0 0 0 0 0 331139 0 0 0 334577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Cytopiloyne+water)ANVALVGTEK MGYG000000142_01601;MGYG000000301_01353;MGYG000001338_00128;MGYG000000216_00449 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2300562 0 0 2626903 0 0 0 0 0 0 -(Cytopiloyne+water)ASGNIIPSSTGAAK MGYG000002934_01252;MGYG000000196_00479;MGYG000002478_03999;MGYG000003819_01468;MGYG000001783_01519;MGYG000002549_00455;MGYG000001415_02219;MGYG000001789_00244;MGYG000004536_01441;MGYG000000243_01331;MGYG000004006_01717;MGYG000002007_00386;MGYG000000170_00182;MGYG000003202_00946;MGYG000000003_00712 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.4 976|Bacteroidetes 0.8666666666666667 G 0.5333333333333333 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 0.9333333333333333 - 0.9333333333333333 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9333333333333333 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 10506088 9169411 5944870 0 0 0 0 0 0 8363624 0 0 0 0 0 0 0 5439523 0 6047155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3584607 3167281 2278255 0 0 0 0 0 0 2782553 0 0 0 0 0 0 0 3332704 0 327026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Cytopiloyne+water)LNENDDADETEIK MGYG000000249_00984 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,27I5J@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Peptidase family M20/M25/M40 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1047977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Cytopiloyne+water)NAVYPQAELMENVLK MGYG000003921_01192;MGYG000002274_00044;MGYG000001300_00295;MGYG000000039_00171;MGYG000002059_01523;MGYG000003899_01136;MGYG000000022_01324;MGYG000002040_01715;MGYG000001255_01114;MGYG000003166_01334 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Cytopiloyne+water)QLQEIAQTK MGYG000002515_03654 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia fergusonii|m__MGYG000002515 1.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,3ZIPY@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 786149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789145 0 496483 0 0 0 0 0 0 0 0 433848 0 0 0 0 381004 0 0 1838681 0 0 2244461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2127799 0 0 0 0 0 0 640062 0 0 0 662299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Cytopiloyne+water)YILVNTSGK MGYG000000198_04292 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 470975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146586 0 0 0 0 0 0 459372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352279 0 0 0 0 0 0 0 563542 0 0 0 0 0 304372 0 0 0 0 0 0 274703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 440162 0 0 1258870 0 0 0 0 0 2887171 0 0 0 0 0 0 1677979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603220 0 0 0 0 1989092 -(Dansyl)IAVQNELVAAYNELRDELAQEK MGYG000001313_03232 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia,4AMZ4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 COG NOG14449 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ExbD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dehydrated)CGELMMPHR MGYG000000967_00086;MGYG000004781_02148;MGYG000000389_00417;MGYG000001637_01679;MGYG000003828_01159;MGYG000000404_01424;MGYG000002517_01945;MGYG000004891_01821;MGYG000002963_01649;MGYG000004271_01619;MGYG000002131_00197;MGYG000004634_01055;MGYG000000127_02821;MGYG000000271_00778;MGYG000002145_00129;MGYG000000997_00132;MGYG000004210_01966;MGYG000004719_01295;MGYG000001303_02393;MGYG000001683_00880;MGYG000000136_01418;MGYG000002492_01354;MGYG000000245_01688;MGYG000000378_01329;MGYG000001793_00084;MGYG000002974_00298;MGYG000000989_00458;MGYG000002670_00826;MGYG000001027_01111;MGYG000004558_02523;MGYG000001186_01940;MGYG000000489_00567;MGYG000001652_01105 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia 0.45454545454545453 186801|Clostridia 1.0 S 0.7272727272727273 acr, cog1399 0.45454545454545453 - 0.7272727272727273 - 1.0 - 1.0 ko:K07040 0.7272727272727273 - 0.7272727272727273 - 0.7272727272727273 - 1.0 - 1.0 ko00000 0.7272727272727273 - 1.0 - 1.0 - 1.0 DUF177 0.7272727272727273 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.7272727272727273 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6262085 0 0 0 0 -(Dehydrated)CVVTGVEMFR MGYG000000215_00564 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella stercorea|m__MGYG000000215 1.0 COG0050@1|root,COG0050@2|Bacteria,4P1C5@976|Bacteroidetes,2FX1Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 347751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 795995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 929178 0 0 0 0 1197260 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1387491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376035 0 0 0 0 131196 -(Delta_H(2)C(2))AAVEAVK MGYG000002478_01108;MGYG000003510_00246;MGYG000000242_01287;MGYG000001157_00286 domain d__Bacteria 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3WGUG@541000|Ruminococcaceae 0.5 186801|Clostridia 0.75 O 0.5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 0.5 groL 0.5 - 0.5 - 0.75 ko:K04077 0.5 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 0.5 - 1.0 - 0.5 - 0.5 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 0.5 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 0.5 - 1.0 - 1.0 - 1.0 - 0.5 - - - - 0.75 0.75 0.75 0.75 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 0.5 none 1.0 2040145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1565906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Delta_H(2)C(2))EQLVHHDIIDAIENMK MGYG000002494_01934 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,3XNE3@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003872,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005945,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019200,GO:0019318,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035639,GO:0036094,GO:0042802,GO:0042866,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0061615,GO:0061695,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494,GO:1990234 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 iNRG857_1313.NRG857_19550 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6674351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Delta_H(2)C(2))LSTEQMLPIVDK MGYG000000133_01632 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 946856 0 0 0 0 0 0 715084 0 0 0 0 0 0 0 0 0 0 705683 0 -(Delta_H(2)C(2))TGLQVR MGYG000002926_00451 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,2N6S2@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Delta_H(2)C(2))YLMSQPNMVVAPSK MGYG000000087_01399 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp000435795|m__MGYG000000087 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,222GB@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2029959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(DiART6plex)FYGNLDAMFDQIHGK MGYG000000243_02236 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,2FN3G@200643|Bacteroidia,4AK6B@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 bifunctional purine biosynthesis protein PurH 1.0 purH 1.0 - 1.0 2.1.2.3,3.5.4.10 1.0 ko:K00602 1.0 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 1.0 M00048 1.0 R01127,R04560 1.0 RC00026,RC00263,RC00456 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 AICARFT_IMPCHas,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylaminoimidazolecarboxamide formyltransferase. | IMP cyclohydrolase. aminoimidazolecarboxamide ribonucleotide transformylase. | inosinicase. - (6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. | H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. 1.0 1.0 1.0 1.0 Antifolate resistance;Metabolic pathways;One carbon pool by folate;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 3004798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5290560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 674627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(DiART6plex115)VQELSGSDMAHWLK MGYG000002438_02345;MGYG000000243_01742;MGYG000000105_03053;MGYG000002478_02236;MGYG000004797_02345;MGYG000001346_02515 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia,4AKZY@815|Bacteroidaceae 0.8333333333333334 976|Bacteroidetes 1.0 E 1.0 Peptidase C1-like family 0.8333333333333334 pepC 1.0 - 1.0 3.4.22.40 1.0 ko:K01372 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_C1,Peptidase_C1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 bleomycin hydrolase. aminopeptidase C (Lactococcus lactis). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain.-!-Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity.-!-Known from bacteria as well as eukaryotic organisms.-!-Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates.-!-Belongs to peptidase family C1. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(DiART6plex118)PLQVETPERPSGQEDVIQLVTPK MGYG000000098_03129 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides bouchesdurhonensis|m__MGYG000000098 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 192760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264948 0 0 0 0 0 0 0 0 0 0 228658 0 483482 0 0 0 0 0 0 0 0 0 0 0 0 0 851009 0 0 0 0 0 0 0 0 0 0 495878 0 0 0 0 0 0 0 0 0 0 0 0 308639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183825 0 0 0 0 0 0 0 0 0 0 244875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355318 0 0 0 0 0 0 0 0 0 0 0 0 0 232043 0 0 0 0 0 0 0 0 0 0 301123 0 0 0 0 0 0 0 0 0 0 173037 0 -(DiLeu4plex117)LVDDEELIELVEM(Oxidation)EVR MGYG000002997_01472 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Streptococcaceae|g__Lactococcus_A|s__Lactococcus_A piscium_C|m__MGYG000002997 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,42CX2@671232|Streptococcus anginosus group 1.0 91061|Bacilli 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 1.0 - 1.0 ko:K02358,ko:K15771 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20533998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(DiLeu4plex117)VTDPIADMLTR MGYG000004743_00033 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__RF39|f__UBA660|g__HGM10873|s__HGM10873 sp900753645|m__MGYG000004743 1.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,3VQMK@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit 1.0 rpsH 1.0 - 1.0 - 1.0 ko:K02994 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 290192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 637959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361987 0 0 0 0 0 0 0 0 0 0 245835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317692 0 0 0 0 0 0 0 0 0 0 279381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(DiLeu4plex118)TYKAAANATGYDVVLGTSSK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)AAYFC(Carbamidomethyl)TNDAHTEPLLK MGYG000002720_01439;MGYG000002057_00766 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG1609@1|root,COG1609@2|Bacteria,1TSVS@1239|Firmicutes,24CU2@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 Protein of unknown function (DUF3798) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF3798 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 3772552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3188201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)AISGYGNVGWGIMK MGYG000002156_01453 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550585|m__MGYG000002156 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)ALIEAEGDFAR MGYG000000074_02445;MGYG000000003_01106;MGYG000001546_02727;MGYG000001562_02109 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,22U5T@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)ALNPEHPVLR MGYG000000177_02209;MGYG000003465_01810;MGYG000000036_01152;MGYG000001651_01539;MGYG000004707_01488 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 0.4 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 0.6 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_10,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 0.2 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1267052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)ANSAMITPATASPSPR MGYG000000074_02437 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG4770@1|root,COG4770@2|Bacteria,4NSWV@976|Bacteroidetes,2FRYI@200643|Bacteroidia,22UGJ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Biotin-requiring enzyme 1.0 mmdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2373020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)APAAIGPYSQAK MGYG000000171_01116;MGYG000000213_01248;MGYG000004733_03267;MGYG000002772_01052;MGYG000000200_03694;MGYG000000164_01191;MGYG000000249_02027 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3Y05K@572511|Blautia 0.7142857142857143 186801|Clostridia 1.0 J 1.0 Endoribonuclease L-PSP 0.7142857142857143 - 1.0 - 1.0 3.5.99.10 1.0 ko:K09022 1.0 - 1.0 - 1.0 R11098,R11099 1.0 RC03275,RC03354 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ribonuc_L-PSP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-iminobutanoate/2-iminopropanoate deaminase. enamine/imine deaminase. This enzyme, which has been found in all species and tissues examined, catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.-!-The reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates. (1) 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+). (2) 2-iminopropanoate + H2O = NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)ATVEVTPVLR MGYG000001789_01122;MGYG000002935_01609;MGYG000000243_03128;MGYG000001925_00906;MGYG000002560_00083;MGYG000003693_02255;MGYG000000273_01353;MGYG000000042_01472;MGYG000004797_03123;MGYG000001599_00128;MGYG000002478_01519 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1408084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)DGLAIIK MGYG000001464_01424 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium|s__Fusobacterium polymorphum|m__MGYG000001464 1.0 COG0015@1|root,COG0015@2|Bacteria,378VV@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 F 1.0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily 1.0 purB 1.0 - 1.0 4.3.2.2 1.0 ko:K01756 1.0 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 1.0 M00048,M00049 1.0 R01083,R04559 1.0 RC00379,RC00444,RC00445 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADSL_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adenylosuccinate lyase. succino AMP-lyase. Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole. (1) N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate. (2) (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamide + fumarate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22317500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)DLKDVEDSNLGLK MGYG000003486_02521 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-95|s__CAG-95 sp000436115|m__MGYG000003486 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 965827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)EVTNPTR MGYG000000038_01497;MGYG000000233_00987;MGYG000004733_00603;MGYG000000489_00240;MGYG000004271_01230;MGYG000000076_01005;MGYG000000245_01074;MGYG000000404_00182;MGYG000002992_00818;MGYG000000271_03442;MGYG000000164_01750;MGYG000000255_01679;MGYG000000179_02175;MGYG000000198_04020;MGYG000001311_02983;MGYG000001607_00943;MGYG000001315_01116;MGYG000000077_00888;MGYG000002517_00471;MGYG000000262_00169 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,27VRH@189330|Dorea 0.5 186801|Clostridia 1.0 S 1.0 Protein of unknown function (DUF1667) 0.65 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1667,Molybdop_Fe4S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2341813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)FEAATGVK MGYG000000243_00999 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,2FMV2@200643|Bacteroidia,4AMM1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family 1.0 galE 1.0 - 1.0 5.1.3.2 1.0 ko:K01784 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00361,M00362,M00632 1.0 R00291,R02984 1.0 RC00289 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 UDP-glucose 4-epimerase. uridine diphospho-galactose-4-epimerase. Also acts on UDP-2-deoxyglucose. UDP-alpha-D-glucose = UDP-alpha-D-galactose. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 971385 0 0 0 0 0 0 0 1846077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)FIDAIIKEK MGYG000002515_02505 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia fergusonii|m__MGYG000002515 1.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,3VZ7M@53335|Pantoea 1.0 1236|Gammaproteobacteria 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)FSDFNEDGTVK MGYG000002057_00764;MGYG000002036_00786;MGYG000001632_01270;MGYG000001464_00004 domain d__Bacteria 1.0 COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia 0.5 186801|Clostridia 0.75 E 1.0 Beta-eliminating lyase 1.0 tnaA 0.75 - 1.0 4.1.99.1 1.0 ko:K01667 1.0 ko00380,map00380 1.0 - 1.0 R00673 1.0 RC00209,RC00355 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Beta_elim_lyase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 tryptophanase. TNase. The enzyme cleaves a carbon-carbon bond, releasing indole and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-Also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine and other 3-substituted amino acids. H2O + L-tryptophan = indole + NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 Tryptophan metabolism 1.0 none 1.0 425431 0 359882 0 0 412754 0 0 371546 0 0 0 0 0 0 0 0 0 0 0 0 382472 0 305456 0 262336 0 0 0 0 0 301987 308958 0 0 236095 339249 258665 2514398 0 1514068 0 0 1915919 0 0 2404903 0 0 0 0 0 0 0 0 0 0 0 0 1620884 0 2430013 0 1987184 0 0 0 0 0 1323760 1372313 0 0 2508322 2384588 1413952 1477797 0 909895 0 0 482484 0 0 995287 0 0 0 0 0 0 0 0 0 0 0 0 1318841 0 619886 0 1125712 0 0 0 0 0 930700 987946 0 0 1027058 1330773 919629 527166 0 471678 0 0 510959 0 0 479380 0 0 0 0 0 0 0 0 0 0 0 0 623627 0 565438 0 400016 0 0 0 0 0 333648 496112 0 0 335250 471539 574628 1088897 0 898457 0 0 654258 0 0 1067562 0 0 0 0 0 0 0 0 0 0 0 0 986678 0 1089485 0 1096670 0 0 0 0 0 1048813 1125872 0 0 1292153 1041789 976160 -(Dicarbamidomethyl)GIIAYFR MGYG000004468_01439 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900539755|m__MGYG000004468 1.0 COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,2FM9V@200643|Bacteroidia,22UZW@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner 1.0 lepA 1.0 - 1.0 - 1.0 ko:K03596 1.0 ko05134,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)GISKDVQKGIELAEQLAAALGGGVVGASR MGYG000003166_01338 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539885|m__MGYG000003166 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)HVISLQNDR MGYG000000138_04128;MGYG000002218_01634;MGYG000000196_02325;MGYG000002549_04271;MGYG000001345_03406;MGYG000000029_00500;MGYG000001489_00791;MGYG000000355_01655;MGYG000001461_03026;MGYG000000098_00595;MGYG000002438_00804;MGYG000000044_01660 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia,22Y6V@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 U 1.0 Biopolymer transporter ExbD 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ExbD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 883406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)IAALLASDHVK MGYG000000074_00676 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG4198@1|root,COG4198@2|Bacteria,4NEQC@976|Bacteroidetes,2FPUQ@200643|Bacteroidia,22VDV@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like,SusD-like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1276927 3213532 0 921618 0 0 1900817 0 0 0 0 2465988 0 0 0 0 1679423 0 1826303 298750 0 0 2040628 0 1961590 0 0 2289407 0 0 1634573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1321491 0 0 0 0 0 0 0 973799 0 0 2078001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1361429 0 0 0 0 0 297389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)IDALIGK MGYG000000074_00389;MGYG000000022_01688 domain d__Bacteria 1.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,2FNBF@200643|Bacteroidia,22U65@171550|Rikenellaceae 0.5 976|Bacteroidetes 0.5 J 0.5 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily 0.5 pheT 0.5 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 0.5 6.1.1.20 0.5 ko:K01890 0.5 ko00970,map00970 0.5 M00359,M00360 0.5 R03660 0.5 RC00055,RC00523 0.5 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 0.5 - 1.0 - 1.0 - 1.0 B3_4,B5,FDX-ACB,tRNA_bind 0.5 - 1.0 - 1.0 - 1.0 - 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 0.5 0.5 0.5 0.5 Aminoacyl-tRNA biosynthesis 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2998471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)IGGVIVDGGK MGYG000002517_01802 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 O-acetylhomoserine 1.0 metY 1.0 - 1.0 2.5.1.49 1.0 ko:K01740 1.0 ko00270,ko01100,map00270,map01100 1.0 - 1.0 R01287,R04859 1.0 RC00020,RC02821,RC02848 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12405133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9257652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)IGTTTGTNGTFSLAAPANGK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1121580 0 0 0 0 0 0 0 0 0 0 2727640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)LDKESEPDIYNAIKR MGYG000000142_01678;MGYG000002438_01730;MGYG000000184_00227;MGYG000000179_01927;MGYG000000245_00268;MGYG000000146_00711;MGYG000004735_01737;MGYG000000255_01277;MGYG000004763_01642;MGYG000001338_02508;MGYG000001489_01493 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia 0.5454545454545454 186801|Clostridia 0.7272727272727273 H 0.9090909090909091 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 0.7272727272727273 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1778167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1486439 0 0 3137804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)LEYDLIITGR MGYG000003381_01959 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnoanaerobaculum|s__Lachnoanaerobaculum sp000296385|m__MGYG000003381 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)LGINAGLINR MGYG000001378_04709 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia,4AMCZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1710832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 847384 0 0 0 0 0 0 -(Dicarbamidomethyl)LTGVVVC(Carbamidomethyl)SC(Carbamidomethyl)SPR MGYG000001338_01864;MGYG000000184_02632 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,3Y0ZT@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 4Fe-4S dicluster domain 1.0 - 1.0 - 1.0 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.0 ko:K03388 1.0 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 1.0 M00356,M00357,M00563,M00567 1.0 R04540,R11928,R11931,R11943,R11944 1.0 RC00011 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Fer4,Fer4_10,Fer4_7,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ferredoxin:CoB-CoM heterodisulfide reductase. | coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase. | H2:CoB-CoM heterodisulfide,ferredoxin reductase. | formate:CoB-CoM heterodisulfide,ferredoxin reductase. - HdrABC is an enzyme complex that is found in most methanogens and catalyzes the reduction of the CoB-CoM heterodisulfide back to CoB and CoM.-!-HdrA contains a FAD cofactor that acts as the entry point for electrons, which are transferred via HdrC to the HdrB catalytic subunit.-!-One form of the enzyme from Methanosarcina acetivorans (HdrA2B2C2) can also catalyze EC 1.8.98.4. cf. EC 1.8.98.5, EC 1.8.98.6, and EC 1.8.98.1. | The enzyme, characterized from the archaeon Methanosarcina acetivorans, catalyzes the reduction of CoB-CoM heterodisulfide back to CoB and CoM.-!-The enzyme consists of three components, HdrA, HdrB and HdrC, all of which contain [4Fe-4S] clusters.-!-Electrons enter at HdrA, which also contains FAD, and are transferred via HdrC to the catalytic component, HdrB.-!-During methanogenesis from acetate the enzyme catalyzes the activity of EC 1.8.7.3.-!-However, it can also use electron bifurcation to direct electron pairs from reduced coenzyme F420 toward the reduction of both ferredoxin and CoB-CoM heterodisulfide.-!-This activity is proposed to take place during Fe(III)-dependent anaerobic methane oxidation. cf. EC 1.8.98.5, EC 1.8.98.6, and EC 1.8.98.1. | This enzyme complex is found in H2-oxidizing CO2-reducing methanogenic archaea such as Methanothermobacter thermautotrophicus.-!-It consists of a cytoplasmic complex of HdrABC reductase and MvhAGD hydrogenase.-!-Electron pairs donated by the hydrogenase are transferred via its Delta subunit to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide.-!-The reductase can also form a similar complex with formate dehydrogenase, see EC 1.8.98.6, formate:CoB-CoM heterodisulfide,ferredoxin reductase. cf. EC 1.8.7.3, EC 1.8.98.4, and EC 1.8.98.1. | The enzyme is found in formate-oxidizing CO2-reducing methanogenic archaea such as Methanococcus maripaludis.-!-It consists of a cytoplasmic complex of HdrABC reductase and formate dehydrogenase.-!-Electron pairs donated by formate dehydrogenase are transferred to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide. cf. EC 1.8.7.3, EC 1.8.98.4, EC 1.8.98.5, and EC 1.8.98.1. coenzyme B + coenzyme M + 2 oxidized [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | coenzyme B + coenzyme M + 4 H(+) + 2 oxidized coenzyme F420-(gamma-L- Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 reduced coenzyme F420-(gamma-L-Glu)(n). | coenzyme B + coenzyme M + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H2 + 2 oxidized [2Fe-2S]- [ferredoxin]. | 2 CO2 + coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]- [ferredoxin]. 1.0 1.0 1.0 1.0 Metabolic pathways;Methane metabolism;Carbon metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2785781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)MTGSDFSEITK MGYG000001315_01339;MGYG000001698_02689;MGYG000001338_02804 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,27J0H@186928|unclassified Lachnospiraceae 0.3333333333333333 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2372884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)MVNVYFFGK MGYG000000184_02627;MGYG000001338_01870 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4656@1|root,COG4656@2|Bacteria,1UY26@1239|Firmicutes,24D3I@186801|Clostridia,3Y0XC@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 2Fe-2S iron-sulfur cluster binding domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer2_4,Fer4_7,Fer4_8,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1618293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)MVNVYFFGKK MGYG000000184_02627;MGYG000000142_01107;MGYG000000050_02094;MGYG000001338_01870;MGYG000000216_03378 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia 0.6 186801|Clostridia 1.0 C 1.0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein 0.6 - 1.0 - 1.0 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.6 ko:K03388 0.6 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 0.6 M00356,M00357,M00563,M00567 0.6 R04540,R11928,R11931,R11943,R11944 0.6 RC00011 0.6 ko00000,ko00001,ko00002,ko01000 0.6 - 1.0 - 1.0 - 1.0 FAD_binding_2,Fer4,Fer4_10,Fer4_7,Pyr_redox_2 0.6 - 1.0 - 1.0 - 1.0 - 1.0 ferredoxin:CoB-CoM heterodisulfide reductase. | coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase. | H2:CoB-CoM heterodisulfide,ferredoxin reductase. | formate:CoB-CoM heterodisulfide,ferredoxin reductase. - HdrABC is an enzyme complex that is found in most methanogens and catalyzes the reduction of the CoB-CoM heterodisulfide back to CoB and CoM.-!-HdrA contains a FAD cofactor that acts as the entry point for electrons, which are transferred via HdrC to the HdrB catalytic subunit.-!-One form of the enzyme from Methanosarcina acetivorans (HdrA2B2C2) can also catalyze EC 1.8.98.4. cf. EC 1.8.98.5, EC 1.8.98.6, and EC 1.8.98.1. | The enzyme, characterized from the archaeon Methanosarcina acetivorans, catalyzes the reduction of CoB-CoM heterodisulfide back to CoB and CoM.-!-The enzyme consists of three components, HdrA, HdrB and HdrC, all of which contain [4Fe-4S] clusters.-!-Electrons enter at HdrA, which also contains FAD, and are transferred via HdrC to the catalytic component, HdrB.-!-During methanogenesis from acetate the enzyme catalyzes the activity of EC 1.8.7.3.-!-However, it can also use electron bifurcation to direct electron pairs from reduced coenzyme F420 toward the reduction of both ferredoxin and CoB-CoM heterodisulfide.-!-This activity is proposed to take place during Fe(III)-dependent anaerobic methane oxidation. cf. EC 1.8.98.5, EC 1.8.98.6, and EC 1.8.98.1. | This enzyme complex is found in H2-oxidizing CO2-reducing methanogenic archaea such as Methanothermobacter thermautotrophicus.-!-It consists of a cytoplasmic complex of HdrABC reductase and MvhAGD hydrogenase.-!-Electron pairs donated by the hydrogenase are transferred via its Delta subunit to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide.-!-The reductase can also form a similar complex with formate dehydrogenase, see EC 1.8.98.6, formate:CoB-CoM heterodisulfide,ferredoxin reductase. cf. EC 1.8.7.3, EC 1.8.98.4, and EC 1.8.98.1. | The enzyme is found in formate-oxidizing CO2-reducing methanogenic archaea such as Methanococcus maripaludis.-!-It consists of a cytoplasmic complex of HdrABC reductase and formate dehydrogenase.-!-Electron pairs donated by formate dehydrogenase are transferred to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide. cf. EC 1.8.7.3, EC 1.8.98.4, EC 1.8.98.5, and EC 1.8.98.1. coenzyme B + coenzyme M + 2 oxidized [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | coenzyme B + coenzyme M + 4 H(+) + 2 oxidized coenzyme F420-(gamma-L- Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 reduced coenzyme F420-(gamma-L-Glu)(n). | coenzyme B + coenzyme M + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H2 + 2 oxidized [2Fe-2S]- [ferredoxin]. | 2 CO2 + coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]- [ferredoxin]. 0.6 0.6 0.6 0.6 Metabolic pathways;Methane metabolism;Carbon metabolism;Microbial metabolism in diverse environments 0.6 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 824017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 829207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)QNAYVQEMMK MGYG000002478_01632 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4PIVU@976|Bacteroidetes,2FQ1R@200643|Bacteroidia,4APFX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 D 1.0 Domain of unknown function 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9249365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4836626 5566350 0 0 0 0 0 0 -(Dicarbamidomethyl)SDFSNTTR MGYG000001415_00852;MGYG000004756_00447 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1704413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1238088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)TLEEGQK MGYG000000255_00941 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG1278@1|root,COG1278@2|Bacteria 1.0 2|Bacteria 1.0 K 1.0 Cold shock 1.0 cspA 1.0 - 1.0 - 1.0 ko:K03704 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 CSD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3097535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)VAGTGVDIIAAR MGYG000002517_00471 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 protein with conserved CXXC pairs 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1667,Molybdop_Fe4S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)VIQGMIQGR MGYG000001619_02441;MGYG000000233_01317;MGYG000000205_00610;MGYG000000274_02582;MGYG000000251_01122;MGYG000000194_00522;MGYG000000255_00470;MGYG000000242_00796 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,21ZJJ@1506553|Lachnoclostridium 0.875 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 2775728 0 0 0 0 0 0 0 0 0 3683838 0 0 2541292 0 0 1261731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2497095 2661222 0 3101111 0 0 0 0 0 3923988 0 0 0 3319639 3278163 0 0 3278433 0 2863424 2370938 0 2244020 0 0 0 0 2936730 2710388 0 2811201 2568586 3085331 0 0 0 0 0 0 0 0 0 0 3672702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2514609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2159535 0 2972432 0 0 0 0 0 0 0 0 3051208 3547370 0 0 2581798 2864586 0 2877632 0 3015279 0 0 0 0 3205471 4019121 0 0 0 0 3665358 0 0 0 2741697 2701842 2457990 0 2841035 0 408642 0 0 0 0 857460 -(Dicarbamidomethyl)VWQVFSAAR MGYG000000089_01082 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1769586 0 0 0 0 2352183 0 0 0 0 2107430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dicarbamidomethyl)YGVQVIGC(Carbamidomethyl)PK MGYG000003697_01061;MGYG000000042_02105;MGYG000001346_02907;MGYG000002281_01665;MGYG000002834_01170;MGYG000002080_02441;MGYG000002549_01269;MGYG000002960_01607;MGYG000002293_01291;MGYG000001370_00660;MGYG000003363_03107;MGYG000001630_00093;MGYG000000196_00779;MGYG000002930_01194;MGYG000000098_01850 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 0.5333333333333333 976|Bacteroidetes 1.0 H 0.8666666666666667 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 0.9333333333333333 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 803761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1231678 0 0 0 0 2363061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1505326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742853 0 0 0 0 0 0 0 0 0 0 0 0 -(Diethyl)AAGLYKNER MGYG000000222_02092;MGYG000001302.1_01771;MGYG000001783_01717;MGYG000002478_01473;MGYG000004797_02540;MGYG000002438_03363;MGYG000003701_03757;MGYG000001489_04121;MGYG000000174_02073 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FN0E@200643|Bacteroidia,22WXW@171551|Porphyromonadaceae 0.7777777777777778 976|Bacteroidetes 1.0 H 1.0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA 1.0 kbl 1.0 - 1.0 2.3.1.29 1.0 ko:K00639 1.0 ko00260,map00260 1.0 - 1.0 R00371 1.0 RC00004,RC00394 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine C-acetyltransferase. 2-amino-3-ketobutyrate coenzyme A ligase. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 123443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Diethyl)EVEEMCPVAQGVHHGAAPIPEEAK MGYG000004140_00115;MGYG000000252_02593;MGYG000002989_01139;MGYG000004733_02765;MGYG000000142_02730;MGYG000000133_00505;MGYG000000216_01908;MGYG000001338_01295;MGYG000000031_02289;MGYG000000212_00325;MGYG000002298_00730;MGYG000000301_00648 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,25V1D@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261735 0 396586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Diethyl)GFCAGPSHALIEAAALVK MGYG000001607_00266;MGYG000001315_00855 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,2499C@186801|Clostridia,27V1U@189330|Dorea 0.5 186801|Clostridia 1.0 I 1.0 synthase III 0.5 grdC 1.0 - 1.0 1.21.4.2,1.21.4.3,1.21.4.4 1.0 ko:K21577 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ACP_syn_III,FA_synthesis 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine reductase. | sarcosine reductase. | betaine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. | The reaction is observed only in the direction of sarcosine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.4. | The reaction is observed only in the direction of betaine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.3. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. | [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine. | [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 884455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Diethyl)MAQQALGMVETR MGYG000004799_00497 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Schaedlerella|s__Schaedlerella sp900765975|m__MGYG000004799 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2263223 2691847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Diethyl)NDTAEATIEYK MGYG000003694_02663;MGYG000003694_02659 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter faecis|m__MGYG000003694 1.0 COG0791@1|root,COG0791@2|Bacteria,1V37S@1239|Firmicutes,4HGHH@91061|Bacilli 0.5 91061|Bacilli 0.5 M 0.5 NLP P60 protein 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 NLPC_P60,SLH 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - - - - 0.5 0.5 0.5 0.5 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147586 0 0 0 0 143537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 200384 0 0 0 0 217970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22267536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809409 0 0 0 0 663135 0 0 0 0 728288 0 0 0 0 0 0 0 0 0 0 -(Diethyl)SAALTILEK MGYG000003202_00870 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__UBA3263|s__UBA3263 sp900759865|m__MGYG000003202 1.0 COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,2FRYC@200643|Bacteroidia,22Y12@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Diethyl)SCDAFLEGHFLLSSGR MGYG000001300_02620;MGYG000000022_01702;MGYG000002619_01872;MGYG000001255_00856;MGYG000003291_01862;MGYG000004679_00415;MGYG000000195_02742;MGYG000002274_02246;MGYG000002641_01985;MGYG000002272_01960 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3WH1G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Belongs to the CarA family 1.0 carA 1.0 - 1.0 6.3.5.5 1.0 ko:K01956 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_sm_chain,GATase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127619 0 0 0 0 421985 0 0 0 0 386498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 301306 0 0 0 0 458705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210765 0 0 0 0 193229 0 0 0 0 0 0 0 0 0 0 -(Diethyl)SEAIAEAAIR MGYG000002156_00335 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550585|m__MGYG000002156 1.0 COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,36EW0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 pyruvate flavodoxin ferredoxin oxidoreductase domain protein 1.0 vorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00174 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFOR_II,POR_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 880508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Diethyl)SGAVER MGYG000001314_01816 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bacteroides_F|s__Bacteroides_F pectinophilus|m__MGYG000001314 1.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,269E9@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal L28 family 1.0 rpmB 1.0 - 1.0 - 1.0 ko:K02902 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Diethyl)VEATFELNDANK MGYG000002494_00458 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,3XN7B@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 UPF0234 protein YajQ 1.0 yajQ 1.0 GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 - 1.0 ko:K09767 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF520 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Diethyl)VLC(Carbamidomethyl)EIEAIAVK MGYG000000179_05387 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,267NT@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 1.0 cca 1.0 - 1.0 2.7.7.19,2.7.7.72 1.0 ko:K00970,ko:K00974 1.0 ko03013,ko03018,map03013,map03018 1.0 - 1.0 R09382,R09383,R09384,R09386 1.0 RC00078 1.0 ko00000,ko00001,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 HD,PEGA,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 polynucleotide adenylyltransferase. | CCA tRNA nucleotidyltransferase. RNA adenylating enzyme. | tRNA-nucleotidyltransferase. Also acts slowly with CTP.-!-Catalyzes template-independent extension of the 3'-end of a RNA strand by one nucleotide at a time.-!-Cannot initiate a chain de novo.-!-The primer, depending on the source of the enzyme, may be an RNA or DNA fragment or oligo(A) bearing a 3'-OH terminal group.-!-See also EC 2.7.7.6. | The acylation of all tRNAs with an amino acid occurs at the terminal ribose of a 3' CCA sequence.-!-The CCA sequence is added to the tRNA precursor by stepwise nucleotide addition performed by a single enzyme that is ubiquitous in all living organisms.-!-Although the enzyme has the option of releasing the product after each addition, it prefers to stay bound to the product and proceed with the next addition.-!-Formerly EC 2.7.7.21 and EC 2.7.7.25. ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide. | a tRNA precursor + ATP + 2 CTP = a tRNA with a 3' CCA end + 3 diphosphate. 1.0 1.0 1.0 1.0 Nucleocytoplasmic transport;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Diethylphosphate)RTAIQKEIDQLQSEITR MGYG000000389_01367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900550935|m__MGYG000000389 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1681826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Diethylphosphate)VAIEVPAAMTLDEIWK MGYG000000196_00457 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4983452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Diisopropylphosphate)FLQASFNYER MGYG000000188_01147;MGYG000004681_01085 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG3716@1|root,COG3716@2|Bacteria,2IDHX@201174|Actinobacteria,4CV2V@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 PTS system mannose fructose sorbose family IID component 1.0 - 1.0 - 1.0 - 1.0 ko:K02747 1.0 ko00052,ko02060,map00052,map02060 1.0 M00277 1.0 R08366 1.0 RC00017 1.0 ko00000,ko00001,ko00002,ko02000 1.0 4.A.6.1.4 1.0 - 1.0 - 1.0 EIID-AGA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Galactose metabolism;Phosphotransferase system (PTS) 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)AAALGFFEAAGYTVENGK MGYG000002926_01410 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1052159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1420850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472261 0 -(Dimethyl[AnyN-term](Ethyl)AAGQIDC(Carbamidomethyl)SR MGYG000002506_04505;MGYG000002323_00920 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG3477@1|root,COG3477@2|Bacteria,1MV9E@1224|Proteobacteria,1RYHM@1236|Gammaproteobacteria,3XQGU@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 response to acidic pH 1.0 yagU 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016020,GO:0044464,GO:0050896,GO:0071944 1.0 - 1.0 ko:K08996 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF1440 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12857722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)AALGAGVDKLANTVR MGYG000000245_00416;MGYG000002492_02075;MGYG000004271_02056;MGYG000000489_01318;MGYG000000271_00294 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)AAVAAMNNGDVVLLQNTR MGYG000001255_00368;MGYG000002272_00148;MGYG000001300_02037;MGYG000002223_00500;MGYG000002274_01739;MGYG000003899_01395;MGYG000000022_00457;MGYG000002641_00592;MGYG000002040_00807 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Phosphoglycerate kinase 1.0 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396040 0 0 0 0 0 0 0 0 0 427993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1154574 0 0 0 0 1148119 0 0 0 0 1072067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 719932 0 0 0 0 0 0 0 0 0 457403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)ADKEMTAAGK MGYG000000084_02247;MGYG000001157_02455 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2552928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106739 0 0 0 0 61883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)AGNDANVAALGEMWQGGGK MGYG000002492_02667 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,2684W@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 GK 1.0 ROK family 1.0 glcK 1.0 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Neomycin, kanamycin and gentamicin biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1152262 0 0 0 0 713091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)ATVESGGAEVGTK MGYG000001306_00336 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG3637@1|root,COG3637@2|Bacteria,4NRZA@976|Bacteroidetes,2FQ3Q@200643|Bacteroidia,4AQ2G@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 COG NOG19089 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,OMP_b-brl,OMP_b-brl_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5495325 0 0 0 0 8172205 0 0 0 0 6155824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302020 0 0 0 0 652083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)EDGAAITYK MGYG000000036_00872 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Pseudoruminococcus|s__Pseudoruminococcus massiliensis|m__MGYG000000036 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)EDIATAIVTGVEMFR MGYG000002997_01472 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Streptococcaceae|g__Lactococcus_A|s__Lactococcus_A piscium_C|m__MGYG000002997 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,42CX2@671232|Streptococcus anginosus group 1.0 91061|Bacilli 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 1.0 - 1.0 ko:K02358,ko:K15771 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 612058 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)FGQGEAAPVVAPAPAPAPEVQTK MGYG000002515_01045;MGYG000002323_01572;MGYG000002506_00283;MGYG000002507_01860 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3XMXT@561|Escherichia 0.75 1236|Gammaproteobacteria 1.0 M 1.0 Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes 0.75 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5322900 0 4713103 0 0 4341652 0 0 0 0 0 0 4554505 0 0 0 0 0 0 0 5039824 0 4154497 5500472 4215649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)IVSGGTDNHLMLVDLR MGYG000004712_00408;MGYG000000074_00316;MGYG000001415_00301;MGYG000000206_00151;MGYG000000003_00862;MGYG000001338_00197 domain d__Bacteria 1.0 COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,2FM07@200643|Bacteroidia,22U20@171550|Rikenellaceae 0.5 186801|Clostridia 0.5 E 1.0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism 1.0 glyA 1.0 - 1.0 2.1.2.1 1.0 ko:K00600 1.0 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 1.0 M00140,M00141,M00346,M00532 1.0 R00945,R09099 1.0 RC00022,RC00112,RC01583,RC02958 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 SHMT 1.0 - 1.0 - 1.0 - 1.0 GH13_11 1.0 glycine hydroxymethyltransferase. threonine aldolase. Also catalyzes the reaction of glycine with acetaldehyde to form L-threonine, and with 4-trimethylammoniobutanal to form 3-hydroxy- N(6),N(6),N(6)-trimethyl-L-lysine. (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)- 5,6,7,8-tetrahydrofolate + L-serine. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;Antifolate resistance;One carbon pool by folate;Glycine, serine and threonine metabolism;Cyanoamino acid metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 747127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1188433 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)KKENAVPEIIDNVEALEAK MGYG000000038_01608 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena|m__MGYG000000038 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,27V4C@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7823473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)NALILSEKEENYK MGYG000004733_01558;MGYG000000142_02503;MGYG000000031_02025;MGYG000000133_01785 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase delta subunit 1.0 acsD 1.0 - 1.0 2.1.1.245 1.0 ko:K00194 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 145236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1164943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)NVLSGK MGYG000003683_00886 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CYY6@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 743976 0 0 0 0 3071391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1695212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)QAIPEHLDIDVTELK MGYG000001056_01611 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900556395|m__MGYG000001056 1.0 COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,2FN3J@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance 1.0 ctc 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02897 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L25p,Ribosomal_TL5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1214108 0 0 0 0 0 0 0 0 0 0 0 1159664 0 0 0 0 0 0 0 0 0 0 0 1509525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)SGDIWEVHTNQGVFETK MGYG000000076_01007 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia intestinalis|m__MGYG000000076 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 1.0 186801|Clostridia 1.0 S 1.0 BFD-like [2Fe-2S] binding domain 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1955242 1779505 2093827 0 0 1643550 0 1930943 0 0 2575002 0 0 0 0 0 0 0 2744159 0 2355362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)SIANYLAEQGAK MGYG000002717_00189;MGYG000004876_00379 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,2FMB9@200643|Bacteroidia,4AM6Q@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Oxidoreductase, short chain dehydrogenase reductase family protein 1.0 uxuB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1322485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 715814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 484745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)SILLTAQEMNSPVILGVSEGAGK MGYG000000251_01798 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter saccharivorans|m__MGYG000000251 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2074780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)TDDTDAQC(Carbamidomethyl)EAAK MGYG000000022_00190;MGYG000000489_00610;MGYG000004414_01745;MGYG000001300_00328;MGYG000000573_00415;MGYG000001157_01716;MGYG000002619_02272 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae 0.7142857142857143 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 0.7142857142857143 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,NAD_binding_7,TP_methylase 0.7142857142857143 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1491176 0 0 0 0 0 0 0 1370981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2104184 0 0 0 1631793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Dimethyl[AnyN-term](Ethyl)VRPDFVVSTEPTDGGIYR MGYG000002994_00683;MGYG000000179_04171;MGYG000000198_04462 domain d__Bacteria 1.0 COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,267KB@186813|unclassified Clostridiales 0.6666666666666666 186801|Clostridia 0.6666666666666666 E 1.0 Peptidase dimerisation domain 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 963815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ESP_2H(10))ANYSNGTLYNQK MGYG000000198_03147;MGYG000004087_00695 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,21Y97@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 206524 0 0 0 0 0 0 2014821 0 0 0 2497929 0 0 0 0 0 0 0 0 371868 0 0 0 0 0 0 0 0 3944647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2034518 0 0 0 2106233 0 0 0 0 1150737 0 0 0 0 0 0 0 0 1589011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1608834 0 573533 0 0 0 102927 0 0 0 0 542381 0 0 0 0 0 0 0 0 299141 0 0 0 0 0 0 0 0 0 0 300980 0 0 0 0 0 0 0 0 8905035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10167925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ESP_2H(10))EALQTC(Carbamidomethyl)LDVVNQNR MGYG000000133_01598 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,3XZBA@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GARP,HrpE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ESP_2H(10))FDPVNSLVSGSMTEQQWIDGIK MGYG000002274_00295;MGYG000001300_00512 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ESP_2H(10))MVDDAEMLELVEMEMR MGYG000001313_00097 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ESP_2H(10))YAIPAFNFNNMEQMQAIIK MGYG000000243_02506 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2509144 0 0 0 0 132895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1012295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Ethylphosphate)GPNHGPAPIPEEGK MGYG000004876_02447;MGYG000003312_00750;MGYG000003554_01511;MGYG000001433_00320;MGYG000002560_00821;MGYG000001370_00749;MGYG000000701_01016;MGYG000001345_01938;MGYG000002603_00278;MGYG000001378_03490;MGYG000002455_00322;MGYG000000243_00196;MGYG000000098_01020;MGYG000002080_00204;MGYG000000236_00538;MGYG000001770_01219;MGYG000002561_00907;MGYG000003367_01951;MGYG000002834_01892;MGYG000003891_01819;MGYG000004748_00173;MGYG000000196_00898;MGYG000001780_00166;MGYG000000029_00188;MGYG000004185_01309;MGYG000002133_00565;MGYG000002281_03939;MGYG000004797_02908;MGYG000003697_02278;MGYG000003363_00818;MGYG000001657_01849;MGYG000001346_01122;MGYG000004456_01424;MGYG000001806_00887;MGYG000004479_00890;MGYG000003681_01495;MGYG000000707_02289;MGYG000002293_01604;MGYG000000272_02235 domain d__Bacteria 1.0 COG1196@1|root,COG1196@2|Bacteria,1TR05@1239|Firmicutes,24BXV@186801|Clostridia,25WTM@186806|Eubacteriaceae 0.6153846153846154 186801|Clostridia 0.6153846153846154 D 0.6153846153846154 nuclear chromosome segregation 0.6153846153846154 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 0.6153846153846154 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 925948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1705119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Ethylphosphate)IIGDLELDQTLTSR MGYG000002279_00846 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena_B|m__MGYG000002279 1.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,27UYM@189330|Dorea 1.0 186801|Clostridia 1.0 O 1.0 prohibitin homologues 1.0 qmcA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Band_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 788926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Ethylphosphate)VIKEKYDANIMFLIQQANIR MGYG000003681_02191 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Formyl)DSPYVNDPHDVSIK MGYG000002478_00658 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 2DBBS@1|root,2Z89P@2|Bacteria,4NG8V@976|Bacteroidetes,2FPGU@200643|Bacteroidia,4ANVA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like,SusD-like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 3678573 0 0 0 0 0 0 0 0 0 0 0 0 986225 0 0 0 0 2551296 0 0 0 0 2711339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2961784 0 0 0 0 0 0 0 0 0 0 0 0 874725 0 0 0 0 687108 0 0 0 0 660244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383539 0 0 0 0 0 0 0 0 0 0 0 0 1276017 0 0 0 0 753832 0 0 0 0 939329 0 0 0 0 0 0 0 0 0 0 -(Formyl)ELGLNSETATVFNLK MGYG000001345_04617;MGYG000002438_01730;MGYG000002033_01132;MGYG000002549_03009;MGYG000001655_03297;MGYG000000243_01838;MGYG000002455_01424;MGYG000003681_02208;MGYG000001337_04099;MGYG000001346_02112;MGYG000002171_01126;MGYG000002218_00618;MGYG000004763_01642;MGYG000003546_01574;MGYG000000044_02644;MGYG000004797_03540;MGYG000001604_00090;MGYG000003363_00033;MGYG000001489_01493;MGYG000004822_01333 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,4AMYK@815|Bacteroidaceae 0.85 976|Bacteroidetes 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2321724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1046675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Formyl)GNTDDMKEC(Carbamidomethyl)LK MGYG000002528_01588 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,248JR@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 PFAM Alcohol dehydrogenase zinc-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 ko:K19956 1.0 ko00051,map00051 1.0 - 1.0 R03234 1.0 RC00089 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 988325 0 0 0 617634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 875539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Formyl)GVDKNEIKR MGYG000000196_03974;MGYG000000236_01807;MGYG000004763_01689;MGYG000000013_02251;MGYG000002281_02290 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1980765 0 0 0 0 0 0 -(Formyl)MDKMADVLGR MGYG000000045_02691 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG1455@1|root,COG1455@2|Bacteria 1.0 2|Bacteria 1.0 G 1.0 protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HisKA,PTS_EIIC,PTS_IIB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Formyl)MDQMLLAK MGYG000002485_02054;MGYG000004893_01695;MGYG000004828_00160 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0636@1|root,COG0636@2|Bacteria,37AJP@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 667583 1891886 1280967 0 2152077 2100136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1524625 0 1227289 0 1289373 0 0 0 0 0 2479160 917525 0 0 0 924533 962086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184091 0 0 89223 0 147007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Formyl)MFSYLQK MGYG000002485_02525 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,378A5@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 G 1.0 PTS system 1.0 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Phosphotransferase system (PTS) 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1446602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1582687 0 1196388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114490 0 200960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Formyl)MKELVAK MGYG000000074_00307 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 S 1.0 Histone H1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Hc1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 474948 0 223643 0 0 0 0 1002834 0 213500 0 0 0 0 0 0 0 232924 0 0 0 0 0 0 0 0 0 0 0 622752 0 0 0 0 0 0 0 0 628260 0 499911 0 0 0 0 0 0 910132 0 0 0 0 0 0 0 991048 0 0 0 0 0 0 0 0 0 0 0 476668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 514712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1930590 0 0 0 0 0 0 0 0 0 0 1388919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1274644 0 0 0 0 0 0 0 0 0 0 4440577 5826601 0 0 0 0 0 0 0 0 3606555 0 4535016 0 0 0 0 2450161 0 2926836 0 0 0 0 0 0 0 3101331 0 0 0 0 0 0 -(Formyl)MKELVEK MGYG000004019_00977;MGYG000002281_03860;MGYG000004748_00642;MGYG000003922_01592;MGYG000001346_02634;MGYG000002561_03014;MGYG000000224_00965;MGYG000002470_01930;MGYG000002549_00791;MGYG000002455_04930;MGYG000000098_00150;MGYG000001370_01432;MGYG000000196_01092;MGYG000001470_03728;MGYG000000029_02290;MGYG000003363_02435;MGYG000000013_00813;MGYG000000003_01005;MGYG000001378_02536;MGYG000000054_03375;MGYG000001345_01255 domain d__Bacteria 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes,2FUJN@200643|Bacteroidia,4AS55@815|Bacteroidaceae 0.9047619047619048 976|Bacteroidetes 0.9523809523809523 S 0.9523809523809523 COG NOG16623 non supervised orthologous group 0.9047619047619048 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 1.0 - 1.0 - 1.0 Hc1 0.9523809523809523 - 1.0 - 1.0 - 1.0 - 0.9523809523809523 - - - - 0.9523809523809523 0.9523809523809523 0.9523809523809523 0.9523809523809523 0.9523809523809523 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8648037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3133491 0 0 6086302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5347614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Formyl)MLAHLLK MGYG000000038_02185;MGYG000001311_02933;MGYG000003582_01256;MGYG000001558_01857;MGYG000002619_02023;MGYG000003374_01118;MGYG000000771_01164;MGYG000001412_01313;MGYG000000272_02321;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000001763_00396;MGYG000000223_00996;MGYG000001711_02099;MGYG000004732_01055;MGYG000001255_00370;MGYG000001482_02362;MGYG000001496_01122;MGYG000004493_00097;MGYG000000002_02120;MGYG000002194_02222;MGYG000004271_00554;MGYG000002966_00075;MGYG000004317_00142;MGYG000000233_00345;MGYG000001577_01888;MGYG000000174_02692;MGYG000001652_01009;MGYG000000077_00219;MGYG000000127_04855;MGYG000002993_00787;MGYG000002945_00682;MGYG000000229_00395;MGYG000004610_00503;MGYG000002098_00013;MGYG000002212_00259;MGYG000004826_01307;MGYG000001606_02632;MGYG000000213_00374;MGYG000003465_00706;MGYG000001542_01437;MGYG000002517_01026;MGYG000004707_01697;MGYG000000212_01474;MGYG000002126_00535;MGYG000000515_01608;MGYG000001338_02547;MGYG000003074_01265;MGYG000001493_05257;MGYG000004757_01889;MGYG000002141_01131;MGYG000000217_00275;MGYG000001439_00571;MGYG000000280_02459;MGYG000000249_01352;MGYG000003695_01114;MGYG000004691_00618;MGYG000002641_00563;MGYG000000193_03247;MGYG000000140_01181;MGYG000000080_03115;MGYG000002279_00557;MGYG000004799_00704;MGYG000001814_01253;MGYG000003656_01296;MGYG000000242_02076;MGYG000002492_01379;MGYG000000198_04065;MGYG000001334_01647;MGYG000001199_01005;MGYG000001658_00407;MGYG000001688_03910;MGYG000000278_03657;MGYG000001319_00348;MGYG000000495_01130;MGYG000001303_01883;MGYG000000187_02264;MGYG000003504_01686;MGYG000000371_00136;MGYG000004519_00423;MGYG000000097_00328;MGYG000001525_01747;MGYG000000615_00488;MGYG000001423_00991;MGYG000001157_00577;MGYG000000171_00850;MGYG000000195_01135;MGYG000001008_00728;MGYG000000271_03250;MGYG000000562_01218;MGYG000000022_00437;MGYG000000133_02283;MGYG000002298_02410;MGYG000000489_00503;MGYG000004600_00849;MGYG000000399_00360;MGYG000003694_01737;MGYG000001607_01815;MGYG000000230_01325;MGYG000003355_00996;MGYG000000484_01691;MGYG000001710_00672;MGYG000003001_00320;MGYG000000205_02269;MGYG000000145_03615;MGYG000002528_00367;MGYG000004140_01100;MGYG000002188_01071;MGYG000002286_00420;MGYG000000164_00800;MGYG000001748_01525;MGYG000001714_01796;MGYG000002946_02881;MGYG000000150_00838;MGYG000000404_00344;MGYG000004815_01345;MGYG000000141_02825;MGYG000003552_01242;MGYG000003702_00925;MGYG000001781_01334;MGYG000001542_02015;MGYG000002304_00547;MGYG000004740_01468;MGYG000000045_02136;MGYG000000162_00065;MGYG000000089_01653;MGYG000004296_01958;MGYG000002155_00766;MGYG000000179_02084;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000001299_00204;MGYG000000251_00555;MGYG000002992_00164;MGYG000002974_01418;MGYG000002997_01277;MGYG000001237_01808;MGYG000004785_01017;MGYG000002025_02240;MGYG000002963_04095;MGYG000000463_00862;MGYG000001602_01805;MGYG000002052_00078;MGYG000001970_02077;MGYG000004246_01300;MGYG000000153_00303;MGYG000001315_01699;MGYG000001627_00130;MGYG000001469_02299;MGYG000003409_01628;MGYG000003891_00096;MGYG000001310_02090;MGYG000002445_01920;MGYG000000325_00586;MGYG000000909_00644;MGYG000002234_00398;MGYG000003431_01105;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000004809_00788;MGYG000003450_00202;MGYG000003701_01708;MGYG000001954_02254;MGYG000002638_00362;MGYG000000215_01375;MGYG000001065_01088;MGYG000004810_01402;MGYG000000100_02166;MGYG000002131_02428;MGYG000003335_00316;MGYG000000084_01085;MGYG000001300_02008;MGYG000004866_01631;MGYG000003937_01177;MGYG000000252_01324;MGYG000000365_00999;MGYG000000301_01012;MGYG000004722_00591;MGYG000001186_01925;MGYG000004087_02290;MGYG000000312_01508;MGYG000000204_00778;MGYG000003013_01053;MGYG000002857_01020;MGYG000004288_00401;MGYG000000175_00767;MGYG000004714_00143;MGYG000003133_02653;MGYG000000281_02732;MGYG000001619_01736;MGYG000000398_00286;MGYG000001683_01827;MGYG000001421_02311;MGYG000004789_01485;MGYG000003812_01036;MGYG000004735_01946;MGYG000003503_01071;MGYG000004809_00408;MGYG000004593_01977 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.20398009950248755 186801|Clostridia 0.7711442786069652 C 0.5870646766169154 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.47761194029850745 gap 0.9552238805970149 - 0.9154228855721394 1.2.1.12 0.9850746268656716 ko:K00134 0.9850746268656716 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9850746268656716 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9850746268656716 R01061 0.9850746268656716 RC00149 0.9850746268656716 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9850746268656716 - 0.9950248756218906 - 1.0 - 0.9850746268656716 Gp_dh_C,Gp_dh_N 0.9850746268656716 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9850746268656716 0.9850746268656716 0.9850746268656716 0.9850746268656716 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9850746268656716 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Formyl)MNELVAK MGYG000000243_03163 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes,2FUJN@200643|Bacteroidia,4AS55@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG16623 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Hc1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 75891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635800 0 0 0 0 726566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Formyl)MNKMEDLINMTK MGYG000004719_01173;MGYG000002517_02144 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 2E4IR@1|root,32ZDT@2|Bacteria,1VENP@1239|Firmicutes,24PCY@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236196 0 0 0 0 84091 0 0 1413441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Formyl)MNKYELALVVSAK MGYG000000171_00776;MGYG000000002_03074;MGYG000001338_00370;MGYG000000997_00916;MGYG000003821_02187;MGYG000002966_02660;MGYG000001777_00649;MGYG000004719_00775;MGYG000000184_02505;MGYG000000213_02194;MGYG000000271_02366;MGYG000000245_01910;MGYG000000201_01588;MGYG000004271_01915;MGYG000004733_01692;MGYG000000301_02038;MGYG000002492_02964;MGYG000002517_03265;MGYG000000806_00865 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3Y068@572511|Blautia 0.5789473684210527 186801|Clostridia 1.0 J 1.0 Binds together with S18 to 16S ribosomal RNA 1.0 rpsF 1.0 - 1.0 - 1.0 ko:K02990 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 470104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 373800 0 0 0 0 0 0 0 0 2335071 0 0 0 0 0 487484 0 0 0 0 0 0 326196 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3348433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2288677 0 1680413 0 2955913 0 0 0 0 2875660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2984732 0 0 0 0 0 0 -(Formyl)MPEKIEELVR MGYG000002775_00885;MGYG000004875_00297;MGYG000001718_01281;MGYG000002947_00531;MGYG000003266_00117;MGYG000002065_01444;MGYG000002961_01719;MGYG000003122_01407;MGYG000002050_01845;MGYG000000188_00186 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CUI3@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Arginyl-tRNA synthetase 1.0 argS 1.0 - 1.0 6.1.1.19 1.0 ko:K01887 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03646 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 arginine--tRNA ligase. arginyl-tRNA synthetase. - ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 422861 0 0 0 0 334426 0 0 0 0 0 0 0 0 0 0 0 0 0 238908 281280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261534 0 0 0 0 481569 0 0 0 0 0 0 0 0 0 0 0 0 0 125102 263993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228082 0 0 0 0 401710 0 0 0 0 0 0 0 0 0 0 0 0 0 580248 278092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189266 0 0 0 0 1303654 0 0 0 0 0 0 0 0 0 0 0 0 0 1642528 791252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 542583 0 0 0 0 0 0 0 0 -(Formyl)MQKEALGMIETK MGYG000000262_00362 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,25WKA@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Formyl)MTDFQYLAR MGYG000003899_00591;MGYG000003291_01608;MGYG000003166_00738;MGYG000002651_01639;MGYG000001300_02373;MGYG000002619_01675;MGYG000000022_01425;MGYG000002223_00953;MGYG000002641_02167;MGYG000004679_00018 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3WK2P@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 - 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334395 0 676222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398219 0 200257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Formyl)TLSGENAFK MGYG000000133_01646;MGYG000002517_01317;MGYG000000184_00874;MGYG000001338_01597;MGYG000003821_02419;MGYG000004785_00785;MGYG000002298_00919;MGYG000000171_00267;MGYG000000301_00414;MGYG000000806_01910 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae 0.9 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 - 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2157756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2296411 0 0 0 0 0 0 -(FormylMet)DKMADVLGR MGYG000000045_02691 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG1455@1|root,COG1455@2|Bacteria 1.0 2|Bacteria 1.0 G 1.0 protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HisKA,PTS_EIIC,PTS_IIB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 2129108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 729966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1440147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(FormylMet)NKMEDLINMTK MGYG000004719_01173;MGYG000002517_02144 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 2E4IR@1|root,32ZDT@2|Bacteria,1VENP@1239|Firmicutes,24PCY@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 307776 0 0 0 0 0 0 0 0 0 0 0 0 310630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 984829 0 0 0 0 0 0 0 0 0 0 0 0 980128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 930361 0 0 0 0 0 0 0 0 0 0 0 0 4433214 0 0 0 0 0 0 0 0 0 0 0 -(FormylMet)NKYELALVVSAK MGYG000000184_02505;MGYG000000271_02366;MGYG000001338_00370;MGYG000003821_02187;MGYG000000301_02038;MGYG000002492_02964;MGYG000004719_00775;MGYG000002517_03265;MGYG000000806_00865 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3Y068@572511|Blautia 0.5555555555555556 186801|Clostridia 1.0 J 1.0 Binds together with S18 to 16S ribosomal RNA 1.0 rpsF 1.0 - 1.0 - 1.0 ko:K02990 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 406446 0 339227 0 0 423911 349813 0 0 0 741166 761918 0 0 0 286294 0 347205 0 0 0 800072 547916 0 300405 319814 396483 828965 0 765781 0 0 366229 0 0 253960 0 378387 407765 0 578342 0 0 353128 507911 0 0 0 854273 116653 0 0 0 519831 0 3046027 284107 0 0 177396 1610339 715255 314654 425139 678767 2256039 0 496548 0 0 540869 0 0 559518 348128 807726 448487 0 1035141 0 0 416598 0 0 0 0 639290 533687 0 0 0 1089783 0 626138 341781 0 0 775014 1042309 564614 369621 0 438268 1609547 0 524068 0 0 1411946 0 0 312542 272403 1276310 132685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409793 0 0 0 0 0 0 323394 0 178974 417979 0 0 0 0 0 0 0 213755 221091 0 2810858 0 0 0 0 0 3201891 0 0 0 2804908 1909092 0 0 0 2215306 0 485227 2068430 0 0 2203286 1122856 2634918 3340218 3059914 3440310 1567357 0 1465106 0 0 4302884 0 0 3147989 2193628 0 -(FormylMet)VVQHNLTAMNANR MGYG000004271_01770;MGYG000000153_01160;MGYG000000271_01499;MGYG000000404_00502;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1309110 0 0 0 0 0 0 0 0 0 0 909042 0 -(GIST-Quat)APFGPGANPMHGR MGYG000002506_00229 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1RM96@1236|Gammaproteobacteria,3XMX2@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 formate C-acetyltransferase activity 1.0 pflB 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECH74115_1262.ECH74115_1064,iECIAI39_1322.ECIAI39_2245,iECSP_1301.ECSP_1007,iECs_1301.ECs0986,iEcSMS35_1347.EcSMS35_2218,iG2583_1286.G2583_1138,iSDY_1059.SDY_2358,iZ_1308.Z1248 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 761388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)ATSDQAEEVC(Carbamidomethyl)AAIR MGYG000001645_00996 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eubacterium_G|s__Eubacterium_G sp900550135|m__MGYG000001645 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,27IBE@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 497144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 871541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1179806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)AVAPTVAVCSNC(Carbamidomethyl)GAATLYHR MGYG000003539_00448 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900769405|m__MGYG000003539 1.0 COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,2FUZD@200643|Bacteroidia,22UKC@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal L32p protein family 1.0 rpmF 1.0 - 1.0 - 1.0 ko:K02911 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L32p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 625582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2226591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)DGPTALILSR MGYG000002506_02537 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,3XMMK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate 1.0 tktA 1.0 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,ic_1306.c2990 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 790628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)DNLYVAEC(Carbamidomethyl)YANKGPTMK MGYG000002966_02570 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900551075|m__MGYG000002966 1.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3XZZ2@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome 1.0 rplV 1.0 - 1.0 - 1.0 ko:K02890 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L22 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 971414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)GGLVTAGNASGINDGAAAIVVMSEEK MGYG000000271_02104;MGYG000002517_00540 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)GQHVIVDGK MGYG000004642_01927 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG3628@1|root,COG3628@2|Bacteria,1VFFX@1239|Firmicutes 1.0 1239|Firmicutes 1.0 S 1.0 Protein of unknown function (DUF2634) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF2634 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 495110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1060262 0 0 0 0 0 0 0 0 0 -(GIST-Quat)IDPIFMDLAR MGYG000000271_00961 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG1145@1|root,arCOG02189@2157|Archaea,2Y1K1@28890|Euryarchaeota,246P5@183980|Archaeoglobi 1.0 183980|Archaeoglobi 1.0 C 1.0 4Fe-4S dicluster domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4,Fer4_21,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)IPDGTTLIDPATGK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 131004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295962 0 0 0 0 130441 0 0 1730040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1791481 0 0 0 0 1799120 0 0 528329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 727482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 551531 0 0 0 0 819241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203728 -(GIST-Quat)KATIEKGQPLDLEVANVVASVMK MGYG000000084_01219;MGYG000001627_02121 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 1.0 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 GABAergic synapse;Necroptosis;Glyoxylate and dicarboxylate metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4317137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6294058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)LPGVAAANDK MGYG000001199_01004;MGYG000000142_01978 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3XYK6@572511|Blautia 0.5 186801|Clostridia 0.5 F 0.5 Psort location Cytoplasmic, score 0.5 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1229273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)MFGAEGFEIVAINDLTSPK MGYG000002298_02410;MGYG000000142_01979;MGYG000000171_00850 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)NAALDLAEK MGYG000002545_02171;MGYG000003166_00582;MGYG000001255_00661;MGYG000002040_00479 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 2ET0Z@1|root,33KJ7@2|Bacteria,1VNW5@1239|Firmicutes,254DV@186801|Clostridia,3WQEJ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-ribbon_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2491955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)RPDFVVSTEPTDGGIYR MGYG000000198_04462 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,267KB@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Peptidase dimerisation domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2980491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)SGVLTGLPDAYGR MGYG000002494_01412;MGYG000000037_00273;MGYG000002534_01733;MGYG000001692_01065;MGYG000000323_00781;MGYG000002515_00999;MGYG000000337_02065;MGYG000002507_03821;MGYG000000093_01913;MGYG000002506_00229;MGYG000000989_01728;MGYG000001712_00487;MGYG000001395_02012 domain d__Bacteria 1.0 COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1RM96@1236|Gammaproteobacteria,3XMX2@561|Escherichia 0.3076923076923077 1236|Gammaproteobacteria 0.5384615384615384 C 1.0 formate C-acetyltransferase activity 0.3076923076923077 pflB 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 0.5384615384615384 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECH74115_1262.ECH74115_1064,iECIAI39_1322.ECIAI39_2245,iECSP_1301.ECSP_1007,iECs_1301.ECs0986,iEcSMS35_1347.EcSMS35_2218,iG2583_1286.G2583_1138,iSDY_1059.SDY_2358,iZ_1308.Z1248 0.5384615384615384 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1337994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)SVQALIDC(Carbamidomethyl)MQEFEK MGYG000002171_00856;MGYG000000243_00367;MGYG000002478_03725;MGYG000002549_01442 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,2FMET@200643|Bacteroidia,4AKSS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)TANMISFMADVIGIR MGYG000001714_00587 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus_A|s__Coprococcus_A catus|m__MGYG000001714 1.0 COG0078@1|root,COG0078@2|Bacteria,1TNY4@1239|Firmicutes,249P4@186801|Clostridia,26870@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 1.0 ygeW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)TEPVYYEPAPAPAPK MGYG000000243_02431;MGYG000002171_00876 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2885@1|root,COG2885@2|Bacteria,4NKM0@976|Bacteroidetes,2FP8P@200643|Bacteroidia,4AN93@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 COG2885 Outer membrane protein and related peptidoglycan-associated 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HALZ,OMP_b-brl,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)TFNEYGIDGK MGYG000000243_02990 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507063 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)VYPAVQGQALK MGYG000000243_01886;MGYG000002171_01694 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3465418 3404630 2828835 2838720 4093879 2978622 3042031 0 2182015 0 0 0 0 0 2669335 4555063 3713116 8009643 0 0 2696577 3914539 7026731 3716622 0 3595620 0 7116668 0 0 3547028 0 2991895 0 4685469 0 2760897 2643920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat)YKDPDYSAK MGYG000000196_04182;MGYG000003367_02308;MGYG000000098_00764;MGYG000001345_00362;MGYG000002549_02853;MGYG000002455_00013 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2207@1|root,COG2207@2|Bacteria,4NVK3@976|Bacteroidetes,2FRSW@200643|Bacteroidia,4AN3S@815|Bacteroidaceae 0.8333333333333334 976|Bacteroidetes 1.0 K 0.8333333333333334 transcriptional regulator (AraC 0.8333333333333334 - 1.0 - 1.0 - 0.8333333333333334 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 HTH_18,TPR_8 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 815375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat_2H(3))ATQNSYSVEAAMAK MGYG000001564_00904 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster clostridioformis_A|m__MGYG000001564 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat_2H(3))DNISENTSSAESR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1033845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat_2H(3))DQPFLMPVEDVFTISGR MGYG000001500_01929;MGYG000004201_01254 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,267PG@186813|unclassified Clostridiales 0.5 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat_2H(3))GSIC(Carbamidomethyl)DVADEVIDYLNAK MGYG000001300_01192 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat_2H(6))IPFLHFFDGFR MGYG000002794_00026 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp003487665|m__MGYG000002794 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,36EA6@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 - 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_10,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 5398599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(GIST-Quat_2H(9))VFEFENFTHGSR MGYG000000196_04506;MGYG000002438_03839;MGYG000002455_00199 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 0.6666666666666666 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Galactosyl)EGWYLVNTSGR MGYG000001619_00313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA9502|s__UBA9502 sp900540335|m__MGYG000001619 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 229472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 206288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Galactosyl)SAEKLSSGYR MGYG000000404_00502 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA11774|s__UBA11774 sp003507655|m__MGYG000000404 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 9524267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Galactosyl)SIPVGLSYEYQNIVFDAR MGYG000003697_01780 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,2FU05@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 Outer membrane protein beta-barrel domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OMP_b-brl,OMP_b-brl_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Galactosyl)SREYPRNYINTGISAIDGLTTLIR MGYG000000133_02040 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,3XZA3@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit 1.0 ntpB 1.0 - 1.0 - 1.0 ko:K02118 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GH130 1.0 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25228221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAAAGVGISK MGYG000001306_00929;MGYG000001364_03302;MGYG000003693_01486 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia,4ARQC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2468820 0 0 0 0 0 0 0 0 0 2336937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAAEAVATSEETR MGYG000000074_02304 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,2FNBJ@200643|Bacteroidia,22UXT@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 TamB, inner membrane protein subunit of TAM complex 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AsmA,TamB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1321665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAAEYFGVK MGYG000000243_02695 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0614@1|root,COG0614@2|Bacteria,4NEF0@976|Bacteroidetes,2FNDC@200643|Bacteroidia,4AMJ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 382954 487625 0 0 0 0 487264 0 0 0 0 0 0 0 0 0 0 330757 274286 339952 0 0 0 0 0 0 0 0 0 0 0 604191 498874 0 0 0 615652 0 266612 445052 0 0 0 0 675978 0 0 0 0 0 0 0 0 0 0 355473 402368 357502 0 0 0 0 0 0 0 0 0 0 0 341282 353340 0 0 0 217298 0 71010 176626 0 0 0 0 136108 0 0 0 0 0 0 0 0 0 0 128543 118623 171199 0 0 0 0 0 0 0 0 0 0 0 127018 92278 0 0 0 183753 0 0 86098 0 0 0 0 172845 0 0 0 0 0 0 0 0 0 0 107515 0 210394 0 0 0 0 0 0 0 0 0 0 0 134921 122932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAAPAKK MGYG000003697_01978;MGYG000002293_00413 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,2FMF1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 51875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13095 0 0 0 0 1762704 0 0 0 0 43783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55587 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAAPVEEVKTEAVAAAETEAAPAK MGYG000000198_03437 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24R6P@186801|Clostridia,220KI@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 625644 0 0 0 0 0 0 0 0 675408 0 0 0 542400 437806 0 0 0 0 651393 0 0 0 0 0 638461 0 0 682773 721946 0 0 0 0 567460 0 629969 0 193298 0 0 0 0 0 0 0 0 236702 0 0 0 276135 267542 0 0 0 0 255513 0 0 0 0 0 323058 0 0 156539 204030 0 0 0 0 272111 0 248168 0 590711 0 0 0 0 0 0 0 0 389673 0 0 0 510929 666826 0 0 0 0 305851 0 0 0 0 0 614804 0 0 325181 260262 0 0 0 0 290288 0 269375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150010 0 0 0 0 0 260537 0 0 0 0 0 0 0 0 0 201815 0 0 0 0 203231 0 0 0 336736 0 0 0 0 0 0 0 0 234616 0 0 0 0 0 0 0 0 0 348821 0 0 0 0 0 271918 0 0 344324 228448 0 0 0 0 329879 0 311483 0 -(Gln->pyro-Glu)QADEYKVPR MGYG000004732_02399;MGYG000002224_01124;MGYG000000022_02282;MGYG000001300_00281;MGYG000002619_00484;MGYG000003409_01330;MGYG000001754_00088;MGYG000003412_02031;MGYG000003937_01028;MGYG000002040_01211;MGYG000002057_01067;MGYG000002545_02503;MGYG000000084_01999;MGYG000001157_01851;MGYG000001255_01100;MGYG000002641_00068;MGYG000000039_00482 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.7647058823529411 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 486629 0 0 0 0 0 0 2794764 3333151 5523055 3412310 0 0 0 5569150 0 475431 0 0 0 0 0 0 3851624 3781052 0 0 0 0 530758 3225368 512373 427519 0 0 666558 0 0 690039 433430 737461 0 0 3208263 0 376289 476479 6253287 1075941 1326954 603535 237199 0 0 0 0 939706 0 2202178 0 320075 444626 4175500 0 0 0 0 0 783872 0 2871890 0 407237 594319 0 0 1513651 505212 385896 818069 0 925195 0 733884 667111 3884618 855198 751720 853419 777346 0 165231 643644 0 698636 0 716684 1156709 794504 444022 0 0 0 0 0 333453 0 710896 674437 823972 524210 1649310 0 2940701 1826535 2291654 2372790 2641172 0 2821123 0 2532013 3192832 2727559 2318398 2143984 2553837 2187266 3199754 2800480 2097670 0 2870468 0 2858055 3048937 0 2069097 4507841 0 0 0 0 2879272 2276995 1268563 1997601 2386307 3126850 2398998 0 1690071 2279016 5301172 0 2042519 0 0 0 1891530 741868 0 0 815482 0 0 0 0 0 0 2299140 0 2447292 1947133 0 829065 3275912 0 0 0 0 659637 2186151 0 1397050 0 0 -(Gln->pyro-Glu)QADGAAQDFFVVDDDRVAK MGYG000002293_01420;MGYG000003697_02155 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 666923 0 0 0 0 673472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QADGSRHPFDSFIC(Carbamidomethyl)AK MGYG000001346_01937;MGYG000000196_04945;MGYG000003681_02456;MGYG000001345_04193;MGYG000001313_00382;MGYG000002281_01173;MGYG000001661_01094;MGYG000000054_00269 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,2FMSH@200643|Bacteroidia,4AKTZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Oxidoreductase, short chain dehydrogenase reductase family protein 1.0 idnO 1.0 - 1.0 1.1.1.69 1.0 ko:K00046 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 gluconate 5-dehydrogenase. 5-ketogluconate reductase. - (1) D-gluconate + NADP(+) = 5-dehydro-D-gluconate + H(+) + NADPH. (2) D-gluconate + NAD(+) = 5-dehydro-D-gluconate + H(+) + NADH. 1.0 1.0 1.0 1.0 1.0 none 1.0 103299 0 0 99189 0 0 0 0 0 0 0 211668 0 249725 113223 0 0 0 0 0 0 0 0 0 0 236055 0 0 0 183514 289371 0 0 0 168279 0 200320 0 255744 0 0 317126 0 0 0 0 0 0 0 244617 0 339269 388206 0 0 0 198532 0 0 0 0 0 0 370684 0 0 0 373805 199178 0 0 0 359259 0 231836 0 302406 0 0 230119 0 0 0 0 0 0 0 441568 0 381678 173517 0 0 0 274332 0 0 0 0 0 0 505635 0 0 0 0 368311 0 0 0 424314 0 286818 0 354220 0 0 460943 0 0 0 0 0 0 0 436635 0 438688 569273 0 0 0 543412 0 0 0 0 0 0 559078 0 0 0 485945 287406 0 0 0 635604 0 525287 0 0 0 0 207199 0 0 0 0 0 0 0 0 0 174079 228104 0 0 0 0 0 0 0 0 0 0 118096 0 0 0 112253 276479 0 0 0 176895 0 317729 0 -(Gln->pyro-Glu)QADGSVM(Oxidation)LR MGYG000004797_03519;MGYG000000098_03719;MGYG000000013_03985;MGYG000001345_00516;MGYG000000196_02452;MGYG000002560_00163;MGYG000001346_01624;MGYG000003221_00983;MGYG000004185_01554;MGYG000002549_04587;MGYG000001337_03982;MGYG000003681_02801;MGYG000000243_02576;MGYG000002455_01538;MGYG000002478_00894;MGYG000000236_01868;MGYG000003312_02028;MGYG000001378_04409 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QADGSVMLR MGYG000004797_03519;MGYG000000098_03719;MGYG000000013_03985;MGYG000001345_00516;MGYG000000196_02452;MGYG000002560_00163;MGYG000001346_01624;MGYG000003221_00983;MGYG000004185_01554;MGYG000002549_04587;MGYG000001337_03982;MGYG000003681_02801;MGYG000000243_02576;MGYG000002455_01538;MGYG000002478_00894;MGYG000000236_01868;MGYG000003312_02028;MGYG000001378_04409 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 648554 0 784625 0 0 0 0 0 714123 0 915942 0 0 744083 0 0 500775 0 617361 0 0 0 0 0 0 0 0 0 572152 0 940216 0 0 0 0 611888 0 0 467994 0 502412 0 0 0 0 0 583405 0 647737 0 0 574834 0 0 389822 0 370438 0 0 0 0 0 0 0 0 0 270345 0 282452 0 0 0 0 373687 0 0 283487 0 354103 0 0 0 0 0 489489 0 636354 0 0 434435 0 0 252644 0 281903 0 0 0 0 0 0 0 0 0 352715 0 394284 0 0 0 0 78596 0 0 249493 0 295599 0 0 0 0 0 418366 0 191435 0 0 466010 0 0 244033 0 0 0 0 0 0 0 0 0 0 0 286878 0 275636 0 0 0 0 246679 0 0 205446 0 648452 0 0 0 0 0 656289 0 657366 0 0 407894 0 0 372434 0 163387 0 0 0 0 0 0 0 0 0 257135 0 102479 0 0 0 0 271882 -(Gln->pyro-Glu)QADGTYSVDITDVK MGYG000001319_01521 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 28JY0@1|root,2Z9ND@2|Bacteria,4NIG7@976|Bacteroidetes,2FV40@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko:K21571 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF5115,SusE,SusF_SusE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1898402 0 0 0 0 1093007 0 0 0 0 1657683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QADIDSGKETIVGLNK MGYG000000742_00316 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900541605|m__MGYG000000742 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H37I@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1307031 0 0 0 0 1982969 0 0 0 0 1525807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QADIIMILINDEK MGYG000000212_02114;MGYG000000251_00670;MGYG000000258_00558;MGYG000000262_00972 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3XYWE@572511|Blautia 0.5 186801|Clostridia 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 899021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QADKYGVPR MGYG000004535_00736;MGYG000003383_01370;MGYG000003683_00888;MGYG000001292_02048;MGYG000001423_01465;MGYG000001477_00014;MGYG000002469_00667;MGYG000003452_00659;MGYG000004769_00436;MGYG000002395_00575;MGYG000000036_01379;MGYG000002421_00703;MGYG000003368_00166;MGYG000004564_01656;MGYG000003868_01165 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CYTB@85004|Bifidobacteriales 0.4 186801|Clostridia 0.4 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 0.6 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 821365 0 0 0 1078215 0 0 0 558221 579373 0 789223 0 0 928606 0 0 0 0 0 456281 0 1456128 0 0 0 0 0 0 941223 1417632 0 0 0 0 0 0 0 920186 0 0 0 927438 0 0 0 878678 980677 0 2015828 0 0 1094894 0 1727529 0 0 0 620032 632270 1203952 0 0 0 1541382 928611 0 975976 419897 0 0 0 0 0 0 0 644483 0 0 0 0 0 0 0 0 407015 0 640836 0 0 1138025 0 0 0 0 0 732579 0 0 0 0 0 0 0 0 631959 831215 0 0 0 0 0 0 0 0 0 0 0 884708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 945261 0 998039 0 0 0 0 529299 0 0 194152 0 0 0 0 0 0 0 0 0 0 0 148102 0 0 0 0 0 0 0 0 0 320806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QADKYKVPR MGYG000002218_02522 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides sp000436495|m__MGYG000002218 1.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia,22W0K@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 986536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228190 0 0 0 0 0 0 0 167339 0 323152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47215 0 0 0 0 0 0 0 696282 0 531637 0 0 0 0 0 0 0 0 0 0 0 0 509973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 586657 0 0 0 0 0 0 0 179035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249259 0 0 0 0 0 0 0 1637845 0 258626 0 0 0 0 0 0 0 0 0 0 0 0 557342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3059650 0 0 0 0 0 0 -(Gln->pyro-Glu)QADKYNVPR MGYG000002549_02927;MGYG000002900_01695;MGYG000001489_02612;MGYG000001659_00198;MGYG000001783_02408;MGYG000002203_01145;MGYG000004536_01502;MGYG000002007_02083;MGYG000003693_00191;MGYG000001763_00795;MGYG000003680_01539;MGYG000001302.1_01164;MGYG000004885_00623;MGYG000002293_00507;MGYG000000138_02891;MGYG000000118_01086;MGYG000002478_00801;MGYG000001599_01853;MGYG000000562_01882;MGYG000002275_02119;MGYG000000696_01665;MGYG000000243_01973;MGYG000000044_03026;MGYG000001364_02756;MGYG000004569_00159;MGYG000002603_01769;MGYG000004763_00924;MGYG000002281_02277;MGYG000001770_00611;MGYG000000003_00089;MGYG000002580_00548;MGYG000001346_01521;MGYG000004006_01224;MGYG000001415_01615;MGYG000002561_02173;MGYG000001306_02658;MGYG000001835_01810;MGYG000004756_01926;MGYG000004456_02002;MGYG000003353_00672;MGYG000003701_04692;MGYG000003363_02293;MGYG000000215_01916;MGYG000003926_00227;MGYG000000187_02028;MGYG000000196_03987;MGYG000000825_01836;MGYG000000272_00847;MGYG000004638_00290;MGYG000002438_02206;MGYG000000042_01093;MGYG000001314_02081;MGYG000000174_03528;MGYG000001806_01478;MGYG000002834_00438;MGYG000001337_03891;MGYG000000074_01964;MGYG000001546_01215;MGYG000003355_03290;MGYG000004464_01245;MGYG000001360_01215;MGYG000003546_00261;MGYG000000098_02004 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia,4AKVK@815|Bacteroidaceae 0.30158730158730157 976|Bacteroidetes 0.8888888888888888 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 0.9841269841269841 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 6254765 7363239 12577860 6324136 10545103 6830970 6588157 6552292 5878790 5988228 7764208 6249003 12732584 8669085 7057976 13615994 8074242 5433733 6197160 6391714 6510969 5305931 4164645 6750760 6365283 6807161 6761447 5032346 6868196 8195968 7231493 8761855 10928324 5930204 7895762 5584809 6090520 9790917 5670540 3774971 6354245 5486318 6741205 4765452 4083897 6545828 5992565 6203234 8200914 5766679 12214522 5971181 5505432 7036808 4819207 4238434 5168168 4844226 5163937 4497570 8451707 3432437 5249762 6227649 7060863 7539367 5039420 6115647 5157291 6041700 5123311 5967305 7021963 5613613 5770505 5619111 3837200 4116036 6823985 4073845 8177829 6431644 4667644 4088669 5734056 3560312 5517558 4457083 6720870 4598108 3528116 6275011 4523552 0 4578156 3522555 4021766 3278978 4082748 4098525 5035750 4012201 4301556 0 3956652 4273596 4651206 3549176 3908909 3702175 4360634 6844639 4961439 4573748 5014317 4781603 8550580 4078920 7098925 8598277 5544420 6524555 5175510 6471187 11110963 7811108 10067044 4944735 5940913 8347625 4893845 10155543 5311663 4063238 4488257 11757660 8693784 9469770 8653493 8270253 5289929 9406138 5961325 4831047 6137230 7112174 7734477 5879028 6116705 5436888 6365674 8954836 3958650 3663934 3952591 6431212 7620721 7214934 4608726 5082143 5527399 5141833 7458249 6597231 11803491 3621523 4342827 8399492 5029227 6313439 5217880 6405562 6072485 4683146 6447493 5485257 5098170 8211252 4436708 4645769 4467580 8350288 6046556 5609888 4031919 5542315 5996109 5791124 7631822 5901036 -(Gln->pyro-Glu)QADREGYPEIAEAFKR MGYG000000170_00133;MGYG000001655_01235;MGYG000004830_00759;MGYG000001302.1_00876;MGYG000001641_00704;MGYG000004468_01487;MGYG000001599_02598;MGYG000000243_02810;MGYG000000215_01429;MGYG000003992_02545;MGYG000002171_00343 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1592@1|root,COG1592@2|Bacteria,4NJ7V@976|Bacteroidetes,2FP1G@200643|Bacteroidia,4AKVP@815|Bacteroidaceae 0.45454545454545453 976|Bacteroidetes 0.9090909090909091 C 0.9090909090909091 Psort location Cytoplasmic, score 8.96 0.5454545454545454 rbr3A 0.9090909090909091 - 1.0 - 1.0 - 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 1.0 - 0.9090909090909091 - 1.0 - 1.0 - 1.0 Rubrerythrin 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 450380 654644 1720793 0 1001072 599237 0 811930 0 515911 0 0 782969 659348 0 787897 797307 0 0 0 0 541148 0 626698 0 571069 0 0 0 0 1081808 760309 1566766 0 0 568454 515898 1467985 246975 0 323021 0 230437 0 0 168749 0 299926 0 0 0 369406 0 0 0 0 0 0 0 0 0 0 0 352394 0 0 0 0 0 0 0 0 0 142629 145776 165378 256299 340505 345498 0 230520 324974 0 375370 0 192351 0 0 286724 97126 0 262098 110612 0 0 0 0 187608 0 181424 0 179852 0 0 0 0 218398 229232 211656 0 0 111884 352603 0 243302 0 254297 0 136455 96936 0 235436 0 253498 0 0 0 96572 0 0 470458 0 0 0 0 0 0 213573 0 141788 0 0 0 0 0 105630 189456 0 0 709258 244827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190362 0 0 0 0 0 0 0 0 0 115342 348424 0 0 0 189520 0 -(Gln->pyro-Glu)QADREGYPEIAEAYKR MGYG000000272_02992;MGYG000002293_00120;MGYG000003467_00199;MGYG000001770_01423;MGYG000000074_02407;MGYG000002080_02179;MGYG000001546_02758;MGYG000002834_02175;MGYG000003697_00652;MGYG000000003_01138;MGYG000002960_00848;MGYG000002603_00556 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1592@1|root,COG1592@2|Bacteria,4NJ7V@976|Bacteroidetes,2FP1G@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 0.6666666666666666 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 430637 0 460566 302936 0 293237 198942 0 354548 496581 0 307727 0 450892 0 0 416832 0 0 0 0 0 0 299773 411920 295660 450568 0 202879 0 224666 330099 0 193409 0 0 224687 0 324756 0 307219 423951 0 0 295250 0 0 406721 0 0 0 189678 326169 0 0 0 0 0 0 300764 0 262976 154115 308362 0 0 341883 0 243673 0 145345 0 413720 0 0 250659 0 0 0 0 0 0 0 205238 180194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340359 0 0 0 0 0 0 0 270782 0 0 0 0 1144610 1712515 2132362 1409481 1690768 2403875 1708065 1569896 1473972 2094541 2063855 2085237 1889864 1060801 1638113 1412130 1372704 3182500 0 1219714 0 2410216 5581167 1866035 1480327 1510270 1336108 5778816 2195619 0 2529936 2255846 1585702 1932676 2160522 0 1308254 2127244 0 175553 360845 723202 236031 272157 231169 0 0 334675 102713 0 565517 108852 0 0 220485 0 0 296341 0 0 0 0 253265 194365 249754 0 0 0 390658 532598 381144 0 262843 0 645667 0 -(Gln->pyro-Glu)QADREGYPEVAEAFKR MGYG000002438_03105;MGYG000004797_02618;MGYG000000042_00595;MGYG000001489_02852;MGYG000002281_03982;MGYG000001461_01112;MGYG000003351_03597;MGYG000001644_00337;MGYG000002455_02720;MGYG000002133_01221;MGYG000000098_01044;MGYG000000174_01697;MGYG000002291_00592;MGYG000000222_03431;MGYG000001345_01982;MGYG000002933_00579;MGYG000000196_00855;MGYG000002478_02503;MGYG000002561_03555;MGYG000003312_01033;MGYG000000696_01296;MGYG000003221_02337;MGYG000002549_01165;MGYG000001306_02407;MGYG000001337_03530;MGYG000000781_01988;MGYG000000236_00566;MGYG000001378_03535;MGYG000000054_03085;MGYG000001920_02116 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1592@1|root,COG1592@2|Bacteria,4NJ7V@976|Bacteroidetes,2FP1G@200643|Bacteroidia,4AKVP@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 0.8333333333333334 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1292237 1310253 1735761 1603237 1731234 1611441 1672222 1554287 1611126 1482968 1578913 1347616 1884316 1835401 1376470 2037229 1813875 1472309 1498229 1253108 1484169 1669046 1264257 1764040 1416652 1656651 1464313 1638348 1436588 2290409 1914592 1822517 1627691 1498296 1631457 1487090 1533958 1352619 1188404 942670 1191171 1245680 1427817 1214747 945093 1074134 1101686 1785540 1653142 1449146 1628322 1502308 1522363 1517167 1513627 723391 1037230 617139 1194078 1385680 946128 863120 1495598 1267550 1208003 1009352 1306604 1431956 932615 1631078 736674 1133441 1150271 1034108 1139753 989036 1138213 1344320 1312199 997544 1502537 1830469 984760 1216452 1196380 1231855 1323152 1696418 1461203 1239970 1064404 1268063 1018326 1758436 1035566 837557 1077765 949740 1607437 1190375 1230019 1136129 1593432 1489853 1268639 1079731 1307479 1086708 960696 977786 1308970 1268270 1249636 1016553 2474428 0 1054562 1990011 0 1701716 0 0 2839106 0 1226402 2079445 1572884 1974211 2761810 1569961 0 1083629 0 2044145 2452496 1017601 1849215 1050246 3307538 2309643 2239097 1319087 1385737 0 1144719 0 1150609 0 0 0 2138076 955592 1071318 1001715 1158501 1652946 1969752 1811725 1111030 1342587 1636085 1200926 1675421 1464949 2342869 867210 1393142 1714538 1474222 1232394 1261085 1234890 1279461 1239152 1239575 1251109 1126222 1382420 1053076 1397747 1322781 1921891 1475258 2067227 1005451 1501589 1893880 1080642 1850665 1550758 -(Gln->pyro-Glu)QADRQDFNHIPAAQWVITK MGYG000002438_01810 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 435591.BDI_2723|- 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 201079 0 313182 0 0 0 0 0 0 0 0 0 0 1783562 0 0 0 0 0 0 1979082 0 0 0 0 0 0 0 0 3384124 0 0 0 0 0 0 0 0 3012623 0 2479323 0 0 0 0 0 0 -(Gln->pyro-Glu)QADTYNVPR MGYG000001615_01715;MGYG000000080_02057;MGYG000000171_02843;MGYG000002279_01931;MGYG000000201_03874;MGYG000000417_00151;MGYG000003013_00348;MGYG000004735_00885;MGYG000002966_00551;MGYG000001688_04230;MGYG000001714_01290;MGYG000001311_05179;MGYG000000271_03364;MGYG000000038_00759;MGYG000001367_00668;MGYG000000133_02992;MGYG000001315_01206;MGYG000003702_00714;MGYG000004380_01409;MGYG000000262_00029;MGYG000001707_01475;MGYG000001379_00688;MGYG000000198_01164;MGYG000001310_01964;MGYG000000077_01356;MGYG000002528_01099;MGYG000000263_00835;MGYG000000179_00921;MGYG000002312_02892;MGYG000001710_02264;MGYG000000216_02407;MGYG000002517_00204;MGYG000001186_01601;MGYG000000909_01303;MGYG000002298_03446;MGYG000000028_00227;MGYG000001531_00907;MGYG000001607_01044;MGYG000004296_01667;MGYG000001637_00070;MGYG000000278_00903;MGYG000003366_00387;MGYG000001338_03374;MGYG000000251_00063;MGYG000000142_00172;MGYG000000233_00808;MGYG000000204_00533;MGYG000000200_01983;MGYG000000050_01748;MGYG000000146_01349;MGYG000000242_00283;MGYG000001303_01923;MGYG000000255_02008;MGYG000004891_02430;MGYG000004087_00550;MGYG000000164_01097;MGYG000000212_03312;MGYG000001374_01219;MGYG000000154_02190;MGYG000002946_01538;MGYG000001777_01731;MGYG000004271_02230;MGYG000002212_00197;MGYG000000249_00027;MGYG000000002_03595;MGYG000001319_01765;MGYG000001496_01735;MGYG000002492_00343;MGYG000001617_01407;MGYG000004359_00697;MGYG000000127_03983;MGYG000000206_00900;MGYG000004733_01212 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.3013698630136986 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 0.9863013698630136 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1585509 1952785 2009196 1185705 2244115 1967823 909711 2323591 1431719 2295913 2161715 2117000 2393611 1726787 2027973 2027712 1620361 2552612 1580177 1802933 1600322 2286267 1704583 892360 2264527 1572864 1538152 2346512 1481460 1717002 769715 1821676 969400 1523367 1555407 1154136 1256819 1084268 1819282 2717345 303432 1883211 1607438 0 1896501 1625805 1279595 1619410 1329247 1025010 1536900 1427800 967972 1021724 607245 2258878 725020 1864905 1427036 0 1686567 1852894 1648668 1458267 2057188 2468010 2359945 1627276 2896932 1825283 1212885 1733476 1773494 1674671 1330711 1365668 1737050 2530187 1741277 1982884 694638 1091249 1070185 1788912 1082418 1617651 1227565 1148344 1762096 1812004 1884493 1967793 1821920 741867 1515769 1452767 956951 2449460 1192254 912057 1627730 1403595 2205573 2343851 1682689 1327029 1115925 2545335 2048462 1723974 2143949 876227 1361894 1541927 1769405 1772609 1325116 1888904 1471367 951140 1284895 2183244 1983707 1612224 1347829 1449615 1898194 1806488 2041704 1430884 1931094 941783 1674820 2092890 1520801 1210250 966007 1375852 1957797 1853536 2072255 1330279 1928738 1821105 1724320 1670152 198923 1362903 1836833 1556916 1929771 1532034 917267 1280467 2562840 1499442 940958 1754051 2157325 1259800 1615931 3121902 1994046 2058829 1127791 2708873 1630129 1515756 1874210 715831 1606534 1022250 2286481 1085301 1238105 2124013 2768518 1943059 2679799 1373873 1619125 1048204 2146794 445992 6045583 2217282 370111 2764860 2924802 2705129 -(Gln->pyro-Glu)QAEAAAEAAEKDAVK MGYG000000179_03470 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 29UBJ@1|root,30FMY@2|Bacteria,1UE9B@1239|Firmicutes,25J4K@186801|Clostridia,22109@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 549623 0 1042948 416488 1119324 0 0 0 573397 0 582616 0 0 413514 399519 0 226581 0 384373 470044 0 482544 0 782737 0 413854 423398 0 610974 266725 212725 0 1444482 326797 0 360565 420914 1709501 0 0 0 0 0 0 0 0 234694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139320 0 0 0 0 482843 0 397984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324304 0 0 0 0 155350 0 0 0 0 814342 0 807758 0 541154 366605 0 0 391809 0 0 0 0 0 0 0 932952 0 558788 0 0 0 0 806660 0 460333 716479 0 902441 0 807862 0 914178 0 0 404653 621863 497894 1929822 0 793489 1672108 1361394 1123973 0 0 1744356 1417434 971624 0 0 1378371 1797786 0 2208449 0 1704572 2522579 0 945076 0 1588281 0 2151445 1237278 0 2350283 1852489 1177743 0 911297 1297169 0 1301661 2175376 1324428 -(Gln->pyro-Glu)QAEAAAESAEKDAVK MGYG000000198_04357 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 29UBJ@1|root,30FMY@2|Bacteria,1UE9B@1239|Firmicutes,25J4K@186801|Clostridia,22109@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 542572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 844409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133787 273081 0 0 0 0 0 405050 0 0 0 0 0 0 0 0 318008 455536 0 839135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472281 1411137 0 0 0 0 820309 754187 0 0 0 0 0 0 0 0 637597 446773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252188 0 0 -(Gln->pyro-Glu)QAEADKYAAQQR MGYG000002517_02730 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,247MK@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 SPFH Band 7 PHB domain protein 1.0 - 1.0 - 1.0 - 1.0 ko:K07192 1.0 ko04910,map04910 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03036,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Band_7,Flot 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Insulin signaling pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 556475 0 0 793023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 808047 0 0 0 0 0 0 0 0 0 0 581647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166368 0 0 0 0 0 0 0 0 0 0 631974 0 -(Gln->pyro-Glu)QAEAETQTASGLFIPDNAK MGYG000003452_00101;MGYG000000756_01001;MGYG000003683_01174 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4D101@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 288032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325204 0 0 0 0 0 0 1148530 0 0 0 0 834542 0 0 0 503106 820724 794243 0 0 0 906463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAEAIVAEAK MGYG000000198_04357;MGYG000000179_03470 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 29UBJ@1|root,30FMY@2|Bacteria,1UE9B@1239|Firmicutes,25J4K@186801|Clostridia,22109@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 329991 0 362665 0 0 0 0 0 116559 0 0 0 0 0 0 0 0 0 615263 287815 0 606399 0 0 0 112569 241385 0 0 226260 0 0 588638 0 0 339149 0 431810 0 0 165718 0 0 305161 0 0 0 170473 0 0 0 0 0 0 0 0 98035 308692 0 131052 0 404664 0 0 485266 0 0 304964 0 0 0 0 0 0 313758 614397 353862 0 0 0 0 0 0 0 218369 98107 0 0 0 0 226362 0 0 0 191897 223773 0 0 0 0 0 391607 241821 0 0 0 0 0 0 227927 0 375676 0 138679 0 0 0 0 0 0 0 0 296358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144530 0 0 548423 0 429047 0 0 305132 0 0 869221 673561 0 0 0 0 704777 0 0 0 514784 825020 0 581337 0 844043 0 1172033 848599 0 0 832559 0 0 429657 566292 0 691638 901279 1126392 -(Gln->pyro-Glu)QAEAQTQTASGLYIPDNAK MGYG000001292_02387 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4D101@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 884534 0 0 0 0 679578 0 0 0 0 1176554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAEENAKEK MGYG000000080_02732 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994041 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAEGM(Oxidation)SWAAEHVVGVAK MGYG000000133_01999 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 945194 1396768 904828 1581183 0 1033660 1233128 0 1092055 1570974 2167714 1224358 2689413 1408206 1119823 1206185 922935 0 1278995 0 994836 1118750 0 851733 1360303 1207900 928511 0 1484914 0 963790 2674063 1998184 1487818 0 1054552 1505782 963530 -(Gln->pyro-Glu)QAEGMSWAAEHVVGVAK MGYG000000133_01999 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 307761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493462 0 0 0 0 0 952362 0 0 0 0 0 0 0 0 0 0 0 225185 0 0 0 0 0 0 1293449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2244397 2576309 2069293 4298426 773291 1779826 2781861 1526042 1972632 3120105 4053770 2140208 3599913 3224314 2269983 1831202 2444026 0 2348052 0 2316070 1153705 0 1469485 2290372 2455538 2271018 0 3401261 0 2353395 4594362 3523885 2255138 1936350 2235906 2019528 1958200 -(Gln->pyro-Glu)QAEGNVLVPYR MGYG000000074_01523 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,22UVQ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 749237 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAEVHGMSQR MGYG000001787_00875;MGYG000000222_02316;MGYG000004479_01009;MGYG000004823_02546;MGYG000002935_02200;MGYG000003521_00869;MGYG000002438_02777;MGYG000003223_00829;MGYG000004006_01367;MGYG000003469_01108;MGYG000000354_01226;MGYG000001337_02097;MGYG000000044_02502;MGYG000002418_00346;MGYG000001302.1_02330;MGYG000004464_01478;MGYG000004797_03431;MGYG000003542_00040;MGYG000001750_01691;MGYG000003922_02594;MGYG000001661_02375;MGYG000002291_01399;MGYG000001562_00082;MGYG000002561_02121;MGYG000003351_04377;MGYG000000236_04030;MGYG000000224_02646;MGYG000002540_02695;MGYG000000074_00929;MGYG000003681_01658;MGYG000001346_02972;MGYG000003367_02059;MGYG000001420_02103;MGYG000003429_00309;MGYG000000415_00752;MGYG000000042_01640;MGYG000000003_01691;MGYG000003546_02127;MGYG000000355_01069;MGYG000001372_02690;MGYG000004573_01499;MGYG000000196_04785;MGYG000004468_01092;MGYG000002203_00473;MGYG000001780_04576;MGYG000003908_01857;MGYG000004853_01517;MGYG000003282_00166;MGYG000003363_02416;MGYG000000243_02435;MGYG000001666_01146;MGYG000002171_00872;MGYG000001789_00914;MGYG000000437_01559;MGYG000000170_01475;MGYG000001641_02232;MGYG000002082_01821;MGYG000001378_04698;MGYG000001783_01848;MGYG000000105_00772;MGYG000002560_03681;MGYG000004763_00180;MGYG000002478_02411;MGYG000000098_01750;MGYG000003353_02100;MGYG000004658_00043;MGYG000002218_02977 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1014@1|root,COG1014@2|Bacteria,4NGN3@976|Bacteroidetes,2FP78@200643|Bacteroidia,4AM9G@815|Bacteroidaceae 0.47761194029850745 976|Bacteroidetes 1.0 C 1.0 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin 0.5522388059701493 iorB 0.9552238805970149 - 1.0 1.2.7.8 1.0 ko:K00180 0.9552238805970149 - 1.0 - 1.0 - 1.0 - 1.0 br01601,ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 POR 0.9552238805970149 - 1.0 - 1.0 - 1.0 - 1.0 indolepyruvate ferredoxin oxidoreductase. IOR. Preferentially utilizes the transaminated forms of aromatic amino acids and can use phenylpyruvate and 4-hydroxyphenylpyruvate as substrates.-!-This enzyme, which is found in archaea, is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = (indol-3- yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 1031580 0 0 0 0 0 0 837291 0 0 0 0 0 0 0 0 0 1089418 0 0 0 0 738309 0 0 840234 0 793565 0 0 0 0 0 0 0 0 775674 0 770759 0 0 0 0 0 0 666258 0 0 0 0 0 0 0 0 0 400969 0 0 0 0 580105 0 0 508059 0 263869 0 0 0 0 0 0 0 0 754569 0 664992 0 0 0 0 0 0 785975 0 0 0 0 0 0 0 0 0 713161 0 0 0 0 743440 0 0 594449 0 672831 0 0 0 0 0 0 0 0 829329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454162 0 562561 0 0 0 0 0 0 1149009 0 0 0 0 0 0 0 0 0 178472 0 0 0 0 849392 0 0 1298680 0 782095 0 0 0 0 0 0 0 0 1191174 0 -(Gln->pyro-Glu)QAFGDTLVEDHK MGYG000001157_01264;MGYG000003921_00349 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 1.0 rpsC 1.0 - 1.0 - 1.0 ko:K02982 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 419392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAFHGLYR MGYG000002080_00556;MGYG000001056_02471;MGYG000003493_00796;MGYG000003697_01453;MGYG000000272_00830;MGYG000002293_00490;MGYG000002834_00455 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,2FNEG@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center 1.0 rplF 1.0 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02933 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 262637 485186 0 260407 0 0 0 0 427362 544871 542476 499192 634734 313109 0 107757 383980 0 446270 166670 0 0 178841 707881 398510 693939 484772 394279 0 0 0 395053 564871 413354 0 121338 0 0 0 0 0 0 0 0 0 0 0 0 196017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365794 0 0 0 210237 0 0 0 0 0 403480 0 0 0 0 0 0 0 149347 0 0 0 0 0 0 0 0 0 0 0 0 242838 0 1136626 1374221 4975008 1026823 2667202 3907021 0 1402575 1135726 1190458 4829576 1491282 4234369 1011975 1367539 2518245 1186094 2585048 1024931 941994 0 4400436 4389628 4539297 1467696 1382987 1322091 3266611 0 0 0 1886812 4301484 1387943 1360548 1265966 1168288 5040379 0 0 0 0 0 0 0 0 0 0 97286 0 0 0 0 0 0 423371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253071 0 280984 0 0 -(Gln->pyro-Glu)QAFTQVKIEK MGYG000000271_00118 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 - 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAGDNIGALLR MGYG000001615_01716;MGYG000000171_02844;MGYG000004732_02398;MGYG000002279_01932;MGYG000000385_01364;MGYG000000201_03875;MGYG000000245_03248;MGYG000001688_04229;MGYG000003063_00662;MGYG000004735_00884;MGYG000000280_01200;MGYG000004893_01944;MGYG000000198_01165;MGYG000004893_00932;MGYG000002563_00522;MGYG000001507_06245;MGYG000001315_01207;MGYG000000410_01314;MGYG000000133_02991;MGYG000001602_02247;MGYG000003937_01027;MGYG000001310_01963;MGYG000003273_00234;MGYG000000140_01590;MGYG000001404_04883;MGYG000001623_00993;MGYG000003142_01879;MGYG000002528_01098;MGYG000002202_00030;MGYG000001436_02249;MGYG000001525_00035;MGYG000002563_00509;MGYG000000157_01091;MGYG000001619_01314;MGYG000000179_00920;MGYG000000216_02406;MGYG000000217_01428;MGYG000002517_00205;MGYG000000173_00405;MGYG000002290_01325;MGYG000004296_01668;MGYG000001607_01045;MGYG000001141_02439;MGYG000002059_00460;MGYG000003142_01865;MGYG000000024_03409;MGYG000001652_01300;MGYG000003425_03741;MGYG000000251_00064;MGYG000001338_03373;MGYG000002670_00364;MGYG000000139_00697;MGYG000000233_00807;MGYG000000142_00171;MGYG000000255_02009;MGYG000000349_00457;MGYG000000404_00531;MGYG000004087_00551;MGYG000000084_02000;MGYG000000164_01096;MGYG000000018_00453;MGYG000002126_00299;MGYG000001299_01777;MGYG000002234_01026;MGYG000001606_01669;MGYG000000202_03457;MGYG000001698_04050;MGYG000000212_03313;MGYG000002105_00002;MGYG000001359_01254;MGYG000002224_01123;MGYG000002950.1_00050;MGYG000002837_02416;MGYG000000193_02083;MGYG000002212_00196;MGYG000000249_00026;MGYG000004799_01385;MGYG000004630_01824;MGYG000000501_01307;MGYG000002286_02469;MGYG000001814_01592;MGYG000000262_00030;MGYG000003486_01055;MGYG000003073_01160;MGYG000002772_01895;MGYG000002492_00344;MGYG000001617_01406;MGYG000002596_02296;MGYG000003921_01124;MGYG000001712_00119;MGYG000003620_01283;MGYG000000206_00901;MGYG000004733_01211 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 0.1827956989247312 186801|Clostridia 0.8387096774193549 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.946236559139785 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.946236559139785 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 128054 229974 0 66750 155715 0 432508 320892 250985 0 185211 95458 0 0 190504 75075 109381 0 199220 111454 83499 1073764 189968 0 0 0 670176 93765 0 263958 0 0 0 178946 0 0 172653 0 0 0 0 0 0 0 85793 0 197435 0 0 88280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81520 0 52849 0 0 0 0 321937 0 420821 615145 0 135119 340057 0 482282 554428 355299 0 575646 481659 0 0 459177 420395 0 0 174707 389166 114111 0 0 0 0 0 0 0 0 346034 0 576092 576433 444689 0 0 297742 0 591247 269640 0 506412 488632 0 459471 313310 526600 0 265924 688371 0 0 521513 745103 159790 0 516086 0 191957 500168 453635 0 0 0 608425 799239 0 713572 0 658223 0 630518 0 0 565561 0 0 0 0 65200 0 0 0 103002 114332 0 192516 236116 0 0 0 0 0 0 231623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAGDSVKEEALR MGYG000000089_01181 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405036 0 0 0 0 580845 0 0 0 0 404605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAGIVDPAKVER MGYG000002834_01380;MGYG000000272_02397;MGYG000001056_01919;MGYG000003697_01689;MGYG000002293_01257;MGYG000001770_01876;MGYG000002080_00257 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 0.5714285714285714 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 278010 0 0 336280 0 0 479298 0 0 0 0 0 0 758008 0 0 0 411179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 171529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2693948 0 2014729 2268005 0 1846564 0 0 2779039 0 1544157 0 0 0 0 3962628 0 0 0 1938359 5677107 2095411 0 0 0 4317898 0 0 2456615 0 2397097 0 0 0 0 3051486 0 0 0 0 695735 0 0 0 0 0 468460 0 362635 0 0 0 0 278538 0 0 0 0 485092 549864 0 0 0 421284 0 0 0 0 0 0 0 0 0 428594 -(Gln->pyro-Glu)QAGVVDSGGQGLMQVMK MGYG000000255_00270;MGYG000000087_00334;MGYG000002517_01429;MGYG000000233_01627 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,21XXP@1506553|Lachnoclostridium 0.75 186801|Clostridia 1.0 S 1.0 Dak1_2 0.75 - 1.0 - 1.0 - 1.0 ko:K07030 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Dak1_2,Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 506280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAHWNMR MGYG000002506_00089;MGYG000002323_01394;MGYG000002494_00829;MGYG000002515_00914 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,1RR4N@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 P 1.0 During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction 1.0 dps 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005623,GO:0006950,GO:0008150,GO:0008199,GO:0009289,GO:0009295,GO:0009605,GO:0009991,GO:0031667,GO:0042594,GO:0042802,GO:0042995,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0097159,GO:1901363 1.0 - 1.0 ko:K04047 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03036 1.0 - 1.0 - 1.0 - 1.0 Ferritin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1161188 1145549 908182 998006 1300515 1977058 1784745 2224831 1260371 2170057 91161 1149328 0 1674161 1008001 601449 845014 0 1216459 1181896 1353634 1546428 0 2238393 1526445 939112 1398662 0 1491733 1494220 0 974066 1035557 2310332 2098791 945632 945806 1073192 1858576 2027729 2134749 1976401 2045151 4516647 2500061 1435420 1685024 2792415 919198 1244809 0 1735912 2133585 884422 2031140 0 2739889 1662303 1741342 5227333 0 3654630 1701192 2052123 1547836 0 2395249 1691739 0 2159019 1721698 1806727 2141380 1646218 1589923 1571289 201531 0 493679 0 346734 1256472 516435 643211 308924 783558 251949 239351 0 357059 284221 498591 284885 0 506945 271776 340393 733858 0 851261 611702 158518 327683 0 0 510004 0 0 419452 740958 431662 320976 243594 302685 669856 840873 1167305 225576 301520 1213094 1507351 983234 784021 1409212 457049 441579 0 458187 700109 445123 697131 0 788756 740231 984783 2038184 0 1111601 1218274 967852 826596 0 260439 654834 0 255354 821796 1439712 1233156 874737 550772 716408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAIAESWPNSLDDTC(Carbamidomethyl)AR MGYG000000355_00183;MGYG000001364_03471;MGYG000004479_02858;MGYG000004797_02539;MGYG000003693_03216;MGYG000003701_03756;MGYG000000243_01845;MGYG000002171_01133;MGYG000002478_01472;MGYG000002438_03364;MGYG000000044_00200;MGYG000002218_02050 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 0.75 976|Bacteroidetes 1.0 GM 0.75 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAIAEVEKAEQASA MGYG000000171_00103;MGYG000000201_01930;MGYG000002298_00783;MGYG000000212_00237 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3Y0GK@572511|Blautia 1.0 186801|Clostridia 1.0 U 1.0 COG COG1862 Preprotein translocase subunit YajC 1.0 yajC 1.0 - 1.0 - 1.0 ko:K03210 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2 1.0 - 1.0 - 1.0 Ftsk_gamma,YajC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 854291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1148154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 826583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1243203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAIDGDTAQVGPQIAEK MGYG000003589_02741;MGYG000002926_00638;MGYG000003166_01337;MGYG000000016_02517;MGYG000002673_02002;MGYG000002610_00220;MGYG000002272_01494;MGYG000002086_01704;MGYG000004464_00649;MGYG000000177_02367;MGYG000003291_01729;MGYG000001157_00998;MGYG000001623_01849;MGYG000004271_00471;MGYG000004525_01509;MGYG000001356_00010;MGYG000003442_01120;MGYG000004863_01199;MGYG000003324_00158;MGYG000004679_00692;MGYG000003899_01133;MGYG000002057_00750;MGYG000000177_01042;MGYG000003770_01062;MGYG000000792_00568;MGYG000002105_00078;MGYG000002224_01330;MGYG000000354_00400;MGYG000000022_01321;MGYG000003498_00873;MGYG000004718_00706;MGYG000004196_00483;MGYG000001500_03164;MGYG000004276_00462;MGYG000000084_00626;MGYG000000099_01611;MGYG000002720_01505;MGYG000004866_01547;MGYG000001191_01318;MGYG000003937_01088;MGYG000002040_01718;MGYG000004489_00129;MGYG000002944_02006;MGYG000002619_02236;MGYG000001729_00006;MGYG000001300_00292;MGYG000004732_01391;MGYG000004482_00822;MGYG000002791_00492;MGYG000001643_03098;MGYG000000039_00174;MGYG000002274_00048 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WH8V@541000|Ruminococcaceae 0.4423076923076923 186801|Clostridia 0.9230769230769231 C 1.0 Psort location Cytoplasmic, score 0.5192307692307693 - 0.8076923076923077 - 0.9230769230769231 1.3.1.108 0.8269230769230769 ko:K03521,ko:K22431 0.8269230769230769 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 0.8269230769230769 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 0.8269230769230769 0.8269230769230769 0.8269230769230769 0.8269230769230769 1.0 none 1.0 2902150 3482514 3480259 3492128 2260496 2810106 2873677 3352543 3285871 3892182 2633420 2630853 3542117 3705241 4126819 2934673 3711207 2787264 4483766 3677617 2940443 3551365 2466438 3492361 4058095 3750086 3684758 2445870 2145697 3004976 2893881 2545360 3502715 4896400 3185274 3544663 3092593 3335689 3518359 3252953 3663096 4060651 2743682 4119354 4981966 2566909 3620722 1530109 2401667 4097704 2992426 3846544 4230288 2623498 3672936 2431154 4809496 3936009 2403001 2479550 2842447 3561968 5344554 3819402 4280600 2935099 1374409 3912988 4165628 3735370 3535103 3407218 1980711 2716772 3053232 3221657 1855845 0 1836525 1817773 1406249 1472268 1863529 1693607 1974431 1601119 2162137 2293470 1954830 1688798 1954324 1717196 1720334 1985927 1869900 1637972 1396526 0 2346456 0 1797618 2258707 1709245 2303327 1772998 2036042 1558280 0 1725558 2125630 1847456 1541438 1715725 1607843 2089526 2849292 4615949 2022662 3365504 3120998 3074752 1709774 3345885 3548252 3443092 3845944 3716536 2896927 2938787 2836401 2622365 2285020 4235019 2454588 2685344 2893851 3096220 2787656 2717137 2214235 2725399 2544503 2411594 3275270 3977354 3707692 4929621 4008407 2097189 2643519 3182844 4148144 767581 421420 985327 1162125 317956 735902 1156640 966808 1058683 834351 738657 1251380 660714 1176202 1139345 695053 826377 2060765 288796 394742 589292 313551 2388182 512881 891164 507010 791107 3024859 1119032 584772 975745 341201 1169844 786119 1171416 811807 826579 1168104 -(Gln->pyro-Glu)QAIDGDTAQVGPQLAEK MGYG000002105_00078;MGYG000003589_02741;MGYG000002926_00638;MGYG000000354_00400;MGYG000000022_01321;MGYG000003210_00606;MGYG000001191_00970;MGYG000003899_01133;MGYG000000084_00626;MGYG000003210_01741;MGYG000002791_00492;MGYG000004464_00649;MGYG000001191_01318;MGYG000001577_01511;MGYG000002274_00048 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WH8V@541000|Ruminococcaceae 0.3333333333333333 186801|Clostridia 0.8666666666666667 C 1.0 Psort location Cytoplasmic, score 0.5333333333333333 - 0.8 - 0.8 1.3.1.108 0.7333333333333333 ko:K03521,ko:K22431 0.7333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 0.7333333333333333 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 0.7333333333333333 0.7333333333333333 0.7333333333333333 0.7333333333333333 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1532562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2109497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1528839 0 1302325 0 0 0 0 0 0 0 1734975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1012223 0 0 0 0 0 0 -(Gln->pyro-Glu)QAIDGDTAQVGPQTAER MGYG000000223_02386 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,3VPI5@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 780252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAIDGDTAQVGPQVAEK MGYG000001302.1_00862;MGYG000002438_02893;MGYG000004019_01436;MGYG000004797_03900;MGYG000001346_02513;MGYG000002281_01804;MGYG000003469_01113;MGYG000003701_04105;MGYG000002082_01219;MGYG000000462_00816;MGYG000000224_01763;MGYG000004711_01572;MGYG000000414_01885;MGYG000002033_00724;MGYG000000273_00875;MGYG000003279_00423;MGYG000001313_00857;MGYG000003420_00107;MGYG000001608_02430;MGYG000001364_02529;MGYG000002549_02817;MGYG000004876_02154;MGYG000004468_01621;MGYG000000196_04138;MGYG000003533_01230;MGYG000001750_01698;MGYG000003744_00979;MGYG000000696_01312;MGYG000001789_02010;MGYG000001783_00812;MGYG000003221_01663;MGYG000000348_00234;MGYG000001546_02765;MGYG000004006_00632;MGYG000000043_03473;MGYG000000053_01232;MGYG000001489_04896;MGYG000000355_01943;MGYG000002203_01949;MGYG000003312_03228;MGYG000004757_01583;MGYG000003367_00838;MGYG000001415_00121;MGYG000002561_01048;MGYG000004658_02629;MGYG000003693_03123;MGYG000004105_01672;MGYG000000243_00603;MGYG000004748_00349;MGYG000001503_00715;MGYG000000054_02440;MGYG000000074_02400;MGYG000004479_00382;MGYG000001306_03031;MGYG000001787_00188;MGYG000002933_02399;MGYG000001345_00398;MGYG000002218_00405;MGYG000001871_00778;MGYG000003952_01066;MGYG000000042_01534;MGYG000004536_00209;MGYG000001663_00335;MGYG000000098_00813;MGYG000001433_02399;MGYG000001562_02164;MGYG000001337_03724;MGYG000000781_02566;MGYG000000170_02403;MGYG000003282_00210;MGYG000000442_01089;MGYG000004756_00803;MGYG000004763_00383;MGYG000004899_00349;MGYG000003542_01688;MGYG000003164_01226;MGYG000001461_03959;MGYG000003423_01174;MGYG000000174_04854;MGYG000001429_00437;MGYG000001655_00932;MGYG000001420_01358;MGYG000003681_02881 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,4AN6T@815|Bacteroidaceae 0.46987951807228917 976|Bacteroidetes 0.9879518072289156 C 1.0 Electron transfer flavoprotein 0.4939759036144578 etfB 1.0 - 0.9879518072289156 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 0.9879518072289156 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 472267 0 895584 549147 781481 641110 471456 592975 754668 691442 635717 590109 700159 654956 792653 759990 447321 0 625173 554911 724760 573211 0 784145 628728 618365 582601 274865 421651 778918 772322 631201 853240 0 617809 759693 444165 756968 618359 0 789619 752121 806660 635817 691238 814178 640236 757252 798353 828263 558620 699143 762789 614212 580543 488838 666199 693805 624047 592753 783832 475225 776049 748519 732623 583999 789461 822226 464008 666490 639726 0 600498 480854 724715 604114 273359 0 607211 0 728176 353688 562852 463032 570378 345431 506323 502252 441729 438215 348529 379874 335594 425828 343659 0 351983 0 479696 649916 374899 299143 458731 550004 571063 359592 525935 433990 414494 0 323395 423049 430794 577761 392651 0 478052 0 354059 457066 533902 543614 427658 480720 177928 614819 458434 491336 0 370932 371764 0 386450 0 452253 0 0 0 402831 521689 430301 0 493239 334103 457269 606863 0 0 515870 502054 518462 0 386547 0 777827 1032690 1150168 640088 732201 797647 850769 615737 533474 708677 952428 442601 684911 683755 908062 850048 993016 1110265 602326 617951 896928 787702 714882 663090 598910 536450 677189 1029369 455610 861310 368213 0 318866 620076 806967 717473 -(Gln->pyro-Glu)QAIENKPGAPLK MGYG000002279_01084 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena_B|m__MGYG000002279 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24AN3@186801|Clostridia,27WHN@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 RnfC Barrel sandwich hybrid domain 1.0 prdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,RnfC_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAIHVTK MGYG000000243_00262 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 2733055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAIHVTKK MGYG000000243_00262 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 1032241 0 0 1729694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1374009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAILDAAVANR MGYG000004797_01413;MGYG000002478_01739 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 301376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAILVEPK MGYG000002293_01420;MGYG000003697_02155 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107321 0 0 1193840 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 806560 0 0 0 0 1238252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAISKDNSADADYLR MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1017769 1197539 1588899 1141487 0 0 1130172 0 817784 0 866860 878113 520873 1119946 512964 0 1378723 0 504974 1261253 0 0 0 1089190 514507 557983 507109 0 1072809 1178235 0 770725 0 0 1100544 0 915053 0 178930 380983 501862 367283 602802 278260 346936 362766 478017 759066 549325 357669 464857 497604 671458 429539 449952 0 590578 588098 306697 263373 0 262923 442902 430324 689460 0 624291 413953 360650 809304 512437 0 624695 377206 509172 462155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690117 376046 685951 483068 739528 635887 557843 980223 690562 696109 343913 582691 499791 756018 850875 431884 431474 0 1041875 699500 420144 0 0 0 814786 825800 749080 0 637294 879374 453403 517549 554825 0 753786 667426 927944 469802 1929472 1534019 2478673 3835874 3323167 3494537 1785428 1281281 2328026 3996765 1853426 2599224 3220166 1740823 2203814 1982825 2994604 0 2786880 3223942 1705690 1832668 0 3055107 2053540 2499303 1911638 0 2199319 3356113 2307133 2942311 2083029 0 2462452 2454319 4496924 3315034 -(Gln->pyro-Glu)QAISYSYDRK MGYG000003891_00348 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG4166@1|root,COG4166@2|Bacteria 1.0 2|Bacteria 1.0 E 1.0 transmembrane transport 1.0 - 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 BACON,DUF4374,DUF4488,DUF5011,F5_F8_type_C,M60-like_N,Peptidase_M60,SBP_bac_5,Sulfatase,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1636505 0 0 0 0 1481172 0 0 0 0 1477408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2241597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 912516 0 0 0 0 865974 0 0 0 0 439712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398287 0 0 0 0 762083 0 0 0 0 975056 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAITAAGSGC(Carbamidomethyl)K MGYG000004876_03337;MGYG000001345_01115;MGYG000002218_02990;MGYG000001370_01519;MGYG000001378_02367;MGYG000002455_05114;MGYG000000243_01362;MGYG000003351_01292;MGYG000003363_02359;MGYG000002171_00772;MGYG000001925_01350;MGYG000004797_00961;MGYG000003701_01280;MGYG000004479_01379;MGYG000000013_00650;MGYG000001306_03156;MGYG000002438_02820;MGYG000001783_01305;MGYG000002560_04136;MGYG000000042_00184;MGYG000002478_04055;MGYG000000355_01906;MGYG000001835_00791;MGYG000000098_03753;MGYG000003367_02255;MGYG000000174_04272 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia,4AM3W@815|Bacteroidaceae 0.8076923076923077 976|Bacteroidetes 1.0 C 1.0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 329891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253870 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAITETGLIQGGEIK MGYG000000179_02302 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 299ND@1|root,2ZBPX@2|Bacteria,1UPWV@1239|Firmicutes,25HQW@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 L-2-amino-thiazoline-4-carboxylic acid hydrolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ATC_hydrolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 252625 0 365237 173692 348333 0 552429 0 687983 0 3800358 801787 376909 0 258253 592537 0 513708 210344 266640 0 0 401241 388285 153443 0 0 233888 304810 0 0 391591 0 240045 0 426180 250749 0 0 0 0 239269 0 0 0 0 0 0 0 330637 0 0 0 0 0 0 0 698032 0 0 0 0 0 0 0 0 411226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268756 135402 0 0 0 0 268127 0 0 0 280062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 654861 0 0 0 0 354569 0 0 0 0 0 0 0 0 0 0 0 511089 0 428340 0 311443 0 289945 0 0 0 0 0 1464349 943707 1190046 2368662 1348370 807228 0 854759 1510073 2401591 728409 1596406 1716850 2003064 1619978 758630 1876081 0 1327334 1731525 987844 1099908 0 982188 1382524 2236580 1470180 0 1661373 1306553 1216930 1769017 1366425 1306183 1068549 1314823 2036910 981297 -(Gln->pyro-Glu)QAITNPDNTVSSIKR MGYG000001300_00003;MGYG000002641_01428;MGYG000002619_01365 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3WGES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 267548 0 273416 0 0 278253 254715 0 285587 0 0 0 0 0 0 0 335254 0 0 0 0 243680 0 317719 0 0 0 0 0 0 0 0 361028 0 0 0 0 338882 792788 0 988318 0 0 793351 909788 0 897273 0 0 0 0 0 0 0 863873 0 0 0 0 554994 0 388328 919059 687701 0 0 0 0 0 0 937950 0 0 0 587726 799276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564333 520026 0 0 0 0 0 0 0 0 0 0 302597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAITNPENTVASIKR MGYG000002274_02128;MGYG000000022_02144 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3WGES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1194610 0 0 0 0 1496314 0 0 0 0 1226210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1488331 0 0 0 0 2310145 0 0 0 0 1802413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1990956 0 0 0 0 1698003 0 0 0 0 1961286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 646502 0 0 0 0 884212 0 0 0 0 334913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660053 0 0 0 0 769936 0 0 0 0 828072 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAITNPKR MGYG000000074_02347;MGYG000001787_01989;MGYG000002007_00900;MGYG000004720_01456;MGYG000000941_00572;MGYG000003279_01430;MGYG000000003_01212;MGYG000001789_02778;MGYG000001302.1_00819;MGYG000001562_02334;MGYG000001420_01443;MGYG000003202_00959 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,22UA3@171550|Rikenellaceae 0.5833333333333334 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAITNPQR MGYG000000098_00251;MGYG000000243_00100;MGYG000002478_02522;MGYG000002171_02941;MGYG000000170_00600 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,4ANVI@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 432798 0 0 839948 0 0 0 0 0 0 0 0 0 0 709724 0 511804 0 0 0 0 870037 0 0 0 0 953028 0 0 0 583807 0 0 0 0 0 0 0 454186 0 0 617564 0 0 0 0 0 0 0 0 0 0 619523 0 440990 0 0 0 0 860741 0 0 0 0 672265 0 0 0 502553 0 0 0 0 0 0 0 480013 0 0 627260 0 0 0 0 0 0 0 0 0 0 568068 0 1267148 0 0 0 0 886009 0 0 0 0 849328 0 0 0 127385 0 0 0 0 0 0 0 293804 0 0 133817 0 0 0 0 0 0 0 0 0 0 111975 0 215848 0 0 0 0 246905 0 0 0 0 444649 0 0 0 134235 0 0 0 0 0 0 0 173020 0 0 158690 0 0 0 0 0 0 0 0 0 0 255337 0 409890 0 0 0 0 281924 0 0 0 0 451120 0 0 0 198234 0 0 0 0 0 0 -(Gln->pyro-Glu)QAIVAEVSEVAK MGYG000002514_01948;MGYG000002535_04030;MGYG000002506_03691;MGYG000002323_03991;MGYG000000107_05463;MGYG000003365.1_02175;MGYG000003390_01039;MGYG000003372_03272;MGYG000000235_04432;MGYG000002494_02479;MGYG000002366_04477;MGYG000002500_00410;MGYG000003360_03951;MGYG000002534_04620;MGYG000002515_03652;MGYG000000093_05651;MGYG000002502_01841;MGYG000002507_00341 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,3XM5M@561|Escherichia 0.9444444444444444 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 469971 261507 406321 514527 0 734702 462577 458419 559299 916499 0 0 0 516988 452942 303909 290789 0 489071 467385 539556 611467 0 723018 214824 595960 624111 0 591350 731889 0 254483 357766 538733 268928 649385 318867 0 591893 640954 602214 842838 0 1451697 806264 832900 726168 1170190 0 0 0 1033990 824133 670508 953702 0 1314963 687145 942446 1704660 0 1407406 952879 1034591 729706 0 1002097 1043555 0 736998 630167 639672 633013 605806 701633 546204 408244 289517 364646 333959 0 572085 449433 322047 247212 434484 0 0 0 451063 455576 297581 119243 0 372817 376281 372443 485359 0 589230 339975 394911 490648 0 493816 348436 0 0 341130 616387 289368 340046 271030 287741 308096 248837 368682 178197 0 432834 373363 343032 138590 359528 0 0 0 191946 161014 244811 244564 0 242016 236746 179005 587210 0 267591 332821 299313 187732 0 318483 319085 0 275724 392714 514537 382685 419987 150790 114803 0 0 0 0 0 0 0 0 0 107952 0 0 0 0 0 0 0 0 0 91394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAKPGVK MGYG000000196_03583 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,4AKHK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 197584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1892886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 69545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAKPVETK MGYG000003266_01664;MGYG000002050_01168;MGYG000004681_00242;MGYG000001636_01239;MGYG000002961_00289 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CV5V@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 - 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 434894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1574352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QALAEEMSNQLR MGYG000004735_00784 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,27JJX@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1207153 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QALDNITPQVEVK MGYG000002293_00508;MGYG000003697_01471;MGYG000002834_00437;MGYG000002603_01770 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,22WEA@171551|Porphyromonadaceae 0.75 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1143466 0 0 0 0 0 0 0 1793191 0 0 0 0 0 0 1885459 0 0 0 0 3145356 0 0 0 0 1909933 0 0 0 0 556874 0 0 0 0 1262850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QALELPR MGYG000002477_04285;MGYG000002323_01056;MGYG000002506_04652;MGYG000002515_02505;MGYG000002534_01239;MGYG000002494_00468 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,3VZ7M@53335|Pantoea 0.5 1236|Gammaproteobacteria 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83087 0 188292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 173544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QALENIKPQIEVR MGYG000000953_00047;MGYG000002485_00024 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0049@1|root,COG0049@2|Bacteria,3790N@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724184 1564092 0 959815 1299993 0 751768 0 1993197 2046816 978957 2031224 770933 0 2062139 0 0 0 0 0 1495274 0 1352727 0 0 712346 0 0 0 1616360 810661 1763970 0 0 0 0 1308754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QALENITPQVEVK MGYG000001562_01942;MGYG000002203_01144;MGYG000001415_01614;MGYG000004536_01501;MGYG000001655_00055;MGYG000001420_02919;MGYG000000437_02347;MGYG000001546_01214;MGYG000004756_01927;MGYG000001663_00083;MGYG000000074_01965;MGYG000000053_00690;MGYG000000414_01221;MGYG000003279_01342;MGYG000003542_01354;MGYG000004822_02482;MGYG000001302.1_01163;MGYG000004658_00151;MGYG000003908_02195;MGYG000002082_00490;MGYG000002007_02084;MGYG000003952_00896 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,22V8M@171550|Rikenellaceae 0.8636363636363636 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 349054 0 0 0 0 481778 0 487559 0 525788 0 0 346431 0 0 384922 0 0 528206 509117 554844 274943 0 180702 703776 309621 482118 0 396904 385922 0 0 0 0 0 434496 411169 0 362545 0 0 0 0 168904 0 463032 427935 748255 0 0 247674 0 0 484537 0 0 633918 649505 304422 0 0 301232 390620 453284 0 0 655730 516428 0 0 0 0 0 311790 308176 0 285374 0 0 0 0 289271 0 268432 349379 0 0 0 421814 0 0 197001 0 0 300858 303588 276396 288025 0 0 284929 401462 0 0 277010 321551 0 0 0 0 0 302059 0 0 310455 0 0 609224 0 342888 0 222010 171591 380533 0 0 0 0 0 433972 0 0 191545 259718 0 449277 0 0 0 326152 137740 0 276100 407088 0 0 0 0 0 419486 296615 0 599987 0 0 735202 0 935463 0 671416 797289 654210 0 0 563679 0 0 783377 0 0 1136707 1049969 551694 410203 0 483178 678451 779889 636664 0 667632 977898 0 0 0 0 0 565659 761637 0 -(Gln->pyro-Glu)QALINSLC(Carbamidomethyl)AK MGYG000000233_01229;MGYG000004747_01854;MGYG000000205_02291 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 0.6666666666666666 adh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 837404 0 0 0 0 0 0 1282300 881329 1139884 0 0 0 0 0 0 622421 0 827353 915113 0 0 0 0 1083084 790637 0 0 0 0 0 0 0 983890 0 921179 583483 0 1255251 0 0 0 0 0 0 1932072 283849 1866935 0 0 0 0 0 0 863891 0 1173323 1173745 0 0 0 0 1394129 1207309 0 0 0 0 0 0 0 1945711 0 1130231 877949 0 638385 0 0 0 0 0 0 759130 899941 750251 0 0 0 0 0 0 0 0 811566 271402 0 0 0 0 489858 787250 0 0 0 0 0 0 0 1393403 0 639429 629314 0 0 0 0 0 0 0 0 272539 122571 287767 0 0 0 0 0 0 0 0 201674 401520 0 0 0 0 372499 194473 0 0 0 0 0 0 0 394227 0 0 0 0 0 0 0 0 0 0 0 234598 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330306 251651 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QALTAELSNQMK MGYG000002517_02914 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QALYEAIESR MGYG000001338_03091;MGYG000000200_01731 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 pgcA 1.0 - 1.0 5.4.2.2,5.4.2.8 1.0 ko:K01835,ko:K01840 1.0 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00114,M00549 1.0 R00959,R01057,R01818,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). | phosphomannomutase. phosphoglucose mutase. | phosphomannose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. | alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. | alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 95989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 200911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288887 0 0 0 0 0 0 0 0 374813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333339 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAM(Oxidation)QNVHFR MGYG000004271_01550;MGYG000000271_02821 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG4166@1|root,COG4166@2|Bacteria,1VRU1@1239|Firmicutes,255ES@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 ABC transporter, substrate-binding protein, family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAMQNVHFR MGYG000004271_01550;MGYG000000271_02821 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG4166@1|root,COG4166@2|Bacteria,1VRU1@1239|Firmicutes,255ES@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 ABC transporter, substrate-binding protein, family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 1838608 0 0 0 0 884884 2397506 0 1590497 1204473 0 1154132 0 1854773 1983886 0 0 0 0 1422746 1501664 657890 0 565911 1743416 1562822 1672641 0 0 0 0 0 0 1932915 0 1799406 1723589 0 0 0 0 0 0 303237 0 0 421325 0 0 0 0 0 0 0 0 0 0 235686 0 0 0 0 0 0 569722 0 0 0 0 0 0 0 0 0 0 0 528356 0 0 0 0 246986 566776 0 245479 434036 0 391084 0 262892 342566 0 0 0 0 494184 172405 257150 0 0 709938 338432 478594 0 0 0 0 0 0 624951 0 274104 353686 0 397219 0 0 0 0 0 356317 0 319759 360590 0 663040 0 119072 458542 0 0 0 0 0 604399 205981 0 0 463548 462668 457531 0 0 0 0 0 0 633412 0 490874 316843 0 844884 0 0 0 0 726071 1099997 0 1071391 733675 0 1176113 0 807498 989138 0 0 0 0 1130446 634760 278771 0 736793 918806 838845 808540 0 0 0 0 0 0 1328473 0 846858 1138249 0 -(Gln->pyro-Glu)QAMQNVHFRR MGYG000000271_02821 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG4166@1|root,COG4166@2|Bacteria,1VRU1@1239|Firmicutes,255ES@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 ABC transporter, substrate-binding protein, family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAMSDAGLKPSDLAK MGYG000002720_01392 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,2N6EU@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 O 1.0 MreB/Mbl protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAMSVFKDTR MGYG000000184_01405;MGYG000000198_02298;MGYG000001338_00963;MGYG000000142_01694;MGYG000002312_02533;MGYG000004735_01072 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3WHCQ@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 0.8333333333333334 - 1.0 - 1.0 - 1.0 ko:K10546 1.0 ko02010,map02010 1.0 M00216 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.5 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 539936 0 0 0 0 0 0 0 0 0 364750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 895068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403052 0 0 0 0 0 0 0 0 0 796611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532338 0 0 0 0 0 0 0 0 0 673157 0 0 0 0 0 0 0 0 0 1472640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAN(Deamidated)GAALM(Oxidation)HYGDTTVLSTATASKEPR MGYG000000133_01738;MGYG000001338_01246 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3XZKB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609070 0 0 0 0 0 0 -(Gln->pyro-Glu)QANKYKVPR MGYG000004647_01362;MGYG000000450_01762 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,4PQ8I@995019|Sutterellaceae 0.5 28216|Betaproteobacteria 0.5 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267799 0 0 0 0 253970 0 0 0 0 274952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408148 0 0 0 0 312290 0 0 0 0 214510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAPLASLEEAVVKGLASDKGLFMPMTIK MGYG000001337_01137 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis|m__MGYG000001337 1.0 COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,2FMPH@200643|Bacteroidia,4AKDS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Threonine synthase 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAPVQLDLIK MGYG000002171_01457;MGYG000000243_02392 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0738@1|root,COG0738@2|Bacteria,4NEPI@976|Bacteroidetes,2FP0B@200643|Bacteroidia,4ANX8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Transporter, major facilitator family protein 1.0 gluP 1.0 - 1.0 - 1.0 ko:K02429 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 2.A.1.7 1.0 - 1.0 - 1.0 MFS_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 489463 0 287596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532885 0 0 0 0 81232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166233 0 275947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 198480 0 0 0 0 194870 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQAVVVEEALR MGYG000000223_01130 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,36DHW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQDAIKAEAER MGYG000000249_01234;MGYG000001310_00255 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3XYW8@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 8.87 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 508091 0 0 0 0 0 0 518652 0 0 0 0 0 0 0 0 599818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609569 0 0 0 669583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 465608 0 0 0 200586 0 0 0 0 187771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQDAIKEEAAR MGYG000002042_01031 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-110|s__CAG-110 sp900762935|m__MGYG000002042 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,267MF@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQDAIKEEATR MGYG000000743_01190;MGYG000000163_01035;MGYG000000733_01113 domain d__Bacteria 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,267MF@186813|unclassified Clostridiales 0.3333333333333333 186801|Clostridia 0.6666666666666666 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 0.6666666666666666 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQDAIKSEAER MGYG000000271_00181;MGYG000004271_02124 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQDAIKTEAER MGYG000000150_02990;MGYG000000201_03495;MGYG000000909_00277;MGYG000001687_00923;MGYG000000213_00523;MGYG000000278_03745;MGYG000004785_01641;MGYG000001247_01746;MGYG000000255_00471;MGYG000000136_00722;MGYG000001186_00373;MGYG000000389_00258;MGYG000000002_01239;MGYG000002517_01401;MGYG000000404_00635;MGYG000001315_00796;MGYG000002393_02328;MGYG000000184_03160;MGYG000002492_01612 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,21Y04@1506553|Lachnoclostridium 0.42105263157894735 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 0.9473684210526315 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1544105 2525117 2272163 1086562 2939666 1778677 605153 445034 730120 0 2253234 1461148 2303679 1785583 1420673 2149797 1606821 1446715 1604426 616092 1595037 1764744 509099 778368 1481739 1267436 1014511 553583 0 1531359 944958 2354096 1480303 1527879 745996 1012463 931611 1610082 1395966 3811652 2092373 1553658 2517056 1142512 1374448 1394064 1106319 0 1683249 985551 1634405 1344649 143871 1427483 1102788 1613307 1068357 1322152 1007970 765422 1143532 1291803 1141425 1342502 1233963 2050603 0 1277862 3718265 2430379 2173706 1928440 1497185 1588941 1248975 0 1982015 5380229 6497841 2079138 2568838 1958427 1593785 2439088 1958777 0 2879151 2194173 3983336 1867758 1957201 4236804 1737949 1023587 2344021 2033212 1833719 1712655 1575526 1789711 2329459 1880258 2440022 2080749 0 2632170 2633266 3895581 5490140 2923583 2480626 1825208 2251833 4057308 2914067 3980708 2000836 3027346 2884007 1979556 2110502 3492283 3270132 0 2770159 2800386 2384735 3916760 4148633 3181214 2617627 1028368 3150456 2661906 2238726 1463785 883302 1295576 3597555 3385675 3907800 511158 0 2944905 3344177 3026794 2619312 2653059 3762237 2669968 3383340 2403564 1890032 3797698 4243684 1587937 2150895 3462257 2340331 1780741 2321507 0 1005232 2561936 2214861 2621512 2892533 2126924 2634018 567158 2277880 1661013 2503875 2377655 910036 2829353 729169 2496420 1229678 814282 0 1481581 5578352 4317052 6592254 2837313 2418353 2721921 3005143 3679565 -(Gln->pyro-Glu)QAQDAIKVEAER MGYG000003695_01035;MGYG000004296_02310;MGYG000000146_01613;MGYG000002279_01755;MGYG000002298_01550 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3XYW8@572511|Blautia 0.4 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 0.6 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 646862 460207 826566 414204 0 914531 0 811580 317335 460402 642357 613479 989748 362069 711683 757128 570629 0 651060 557269 516084 1074029 0 301898 602954 499029 370171 0 476224 0 597727 513496 762462 485230 607795 398128 369998 643351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288213 0 0 0 837227 1061065 731745 424248 0 464034 291276 723049 455691 642665 437567 381584 645065 400597 723050 580296 546905 0 668712 781370 533116 977498 0 371930 838206 777918 804179 0 536405 0 632864 985417 768443 929637 787180 466364 638499 649521 0 744622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390175 318668 0 0 0 0 0 0 1780908 1895878 1792169 2435573 0 1224800 2319347 1597794 1399668 2458603 1987427 1546475 1051481 2526054 2011627 1551106 1507413 0 1659866 403879 2154344 1934206 0 1086943 1492957 1406908 1656850 0 2551684 0 1533964 2153795 2926135 2188772 1251650 1811117 1362359 1236286 -(Gln->pyro-Glu)QAQDAVAEEATR MGYG000004788_00490 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Lactobacillaceae|g__Companilactobacillus|s__Companilactobacillus farciminis|m__MGYG000004788 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,3F3M1@33958|Lactobacillaceae 1.0 91061|Bacilli 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 806102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQDSIKNEAER MGYG000000262_02774 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,25UT8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184799 0 0 0 0 762445 0 0 0 459473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825884 0 220567 0 0 0 0 0 0 0 0 0 0 873078 0 0 0 0 421774 0 0 0 523633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 373310 0 416999 0 0 0 0 0 0 0 0 0 0 503156 0 0 0 0 255637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQEAIANQATR MGYG000002469_01208;MGYG000001292_01082 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CZ96@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQEAIKAEAER MGYG000000179_02939 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,21Y04@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 518633 0 0 344827 0 0 0 0 315241 419462 0 0 0 427780 0 0 0 0 0 347615 0 0 0 0 0 360633 0 0 437384 247684 0 0 0 0 0 477169 133920 0 400530 0 0 218261 0 0 0 0 0 210308 0 0 0 150941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 666755 505236 0 0 0 703895 0 0 0 0 0 477875 0 0 0 0 0 401271 460500 0 726840 0 0 0 0 0 0 640541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1090170 0 0 1377297 630337 558783 0 0 1096078 1218555 0 0 0 1035946 0 0 1175234 0 0 1157450 0 692000 0 717389 0 916172 1056565 0 1357547 666311 0 0 0 0 0 786895 1078725 937356 -(Gln->pyro-Glu)QAQEAIKDEAAR MGYG000002720_01476 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,2N6MD@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein S2 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 308351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQEAIKDEALR MGYG000002926_00692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,2N6MD@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein S2 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 657464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQEAVKEEAQR MGYG000001645_00483 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eubacterium_G|s__Eubacterium_G sp900550135|m__MGYG000001645 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,21Y04@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 909646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQEAVKEQAER MGYG000002485_02450;MGYG000004828_01989;MGYG000004893_01903;MGYG000000953_00545;MGYG000002574_00367 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0052@1|root,COG0052@2|Bacteria,3795U@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 996897 0 643932 0 0 472025 0 1231538 1423599 0 994332 637771 0 1040348 558118 0 392839 0 0 851743 0 757223 0 0 569776 0 0 0 0 0 757950 0 0 0 0 617760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQEAVKNAAER MGYG000002947_00285;MGYG000002961_01438;MGYG000004681_00359;MGYG000002775_01738;MGYG000003266_00512;MGYG000001642_01009;MGYG000000188_00078;MGYG000002970_00272 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CU8M@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQEAVKTEAER MGYG000001319_00659 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,4BXU0@830|Butyrivibrio 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein S2 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 966099 0 0 0 0 803005 0 0 0 0 920978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQEAVSNQAVR MGYG000003683_00403 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CZ96@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582624 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 574580 0 202895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQEILDNATNDANNIR MGYG000004719_01421;MGYG000000271_00139;MGYG000000389_00412;MGYG000004271_00266;MGYG000002517_01451 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GARP,HrpE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254060 0 0 0 0 0 0 0 0 0 0 260868 0 193711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572189 0 -(Gln->pyro-Glu)QAQEILDTDHYGLER MGYG000002477_04282;MGYG000002535_03207;MGYG000000235_01944;MGYG000002534_01242;MGYG000002323_01059;MGYG000002494_00471;MGYG000002500_01182;MGYG000002515_02502;MGYG000002506_04655;MGYG000002504_00799;MGYG000003372_00323 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 O 1.0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner 1.0 lon 1.0 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.0 3.4.21.53 1.0 ko:K01338 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,AAA_5,ClpB_D2-small,LON_substr_bdg,Lon_C,zf-C4_ClpX 1.0 - 1.0 - 1.0 - 1.0 - 1.0 endopeptidase La. ATP-dependent serine proteinase. ATP hydrolysis is linked with peptide bond hydrolysis.-!-Vanadate inhibits both reactions.-!-A similar enzyme occurs in animal mitochondria.-!-Belongs to peptidase family S16. Hydrolysis of proteins in presence of ATP. 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 804300 0 313386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQESIRDEALR MGYG000000022_01263;MGYG000001300_00246;MGYG000002223_00595;MGYG000000039_00227;MGYG000002224_00296;MGYG000002274_00630;MGYG000002651_00048;MGYG000002545_00160;MGYG000000195_01345;MGYG000002641_00104 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 938378 0 1271599 1058267 0 963519 616509 666576 852299 0 695677 0 0 1199293 862534 1180012 1200964 2127004 1206286 0 0 858576 1456001 951603 0 960501 883626 1655978 0 675997 767699 819527 1096341 1316190 0 944255 740645 1060057 1510072 0 1961944 1659054 0 1408051 1968715 911116 1915667 0 1506797 0 0 1676649 1646417 917984 1898249 1516865 2344657 0 0 993547 2253781 1330499 0 1665357 1605494 2051696 0 1738333 1528279 1239215 1785867 1492937 0 1493177 1721276 1269933 609690 0 1106472 974273 0 1197763 764508 707719 1024412 0 961200 0 0 748443 743575 871598 643851 2242339 656980 0 0 639747 1926041 761994 0 647114 710090 2733409 0 544149 994621 695167 585903 773584 0 767076 837981 614464 445846 0 1832790 760052 0 1706993 1136127 651725 841609 0 1233359 0 0 799758 943789 728169 528076 1715591 945647 0 0 2190270 2309863 366827 0 1202609 758392 884144 0 1317561 389149 1131057 1563437 1388744 0 896091 1130759 1734573 0 0 468019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1912716 0 0 0 0 2081700 0 0 0 0 2093484 0 0 0 0 604079 0 0 0 0 413571 -(Gln->pyro-Glu)QAQESIRDEATR MGYG000001157_00347;MGYG000003921_00807;MGYG000003937_00035 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQETKVDETAADTK MGYG000000133_01632 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 316871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155620 0 370306 0 0 0 0 0 0 368444 0 0 0 0 290145 0 0 0 0 0 297625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 701548 828864 1564431 1617439 0 668631 1027821 528539 789508 1672299 1271297 1237486 0 1537207 1088395 530472 1229890 0 973585 0 1057717 510067 0 597565 950710 1065764 1010463 0 1130139 0 945875 1182572 2371237 835805 0 0 1049977 1064845 -(Gln->pyro-Glu)QAQQTGVDAK MGYG000002492_01475 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 carboxylase 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300870 0 0 0 0 160796 0 0 649467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 772524 0 0 0 0 594512 0 0 480595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564313 0 0 0 0 809289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQTGGDKAAK MGYG000002549_03298;MGYG000001337_00591;MGYG000000196_03335;MGYG000001780_02910;MGYG000000243_01434;MGYG000004876_00281 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,2FMWX@200643|Bacteroidia,4AMIJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner 1.0 ychF 1.0 - 1.0 - 1.0 ko:K06942 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 MMR_HSR1,YchF-GTPase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 316810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353733 0 0 0 0 199708 0 0 150378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181373 0 0 0 0 282158 0 0 92540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252986 0 0 0 0 220207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47736 0 0 0 0 0 0 0 84610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182805 -(Gln->pyro-Glu)QAQVVMHDQAPALIIAHSTVYEPVRK MGYG000002494_02203 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,3XMYT@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis 1.0 dppA 1.0 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0008150,GO:0009987,GO:0015833,GO:0020037,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042938,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:0097159,GO:1901363 1.0 - 1.0 ko:K02035,ko:K12368 1.0 ko02010,ko02024,ko02030,map02010,map02024,map02030 1.0 M00239,M00324 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 iSSON_1240.SSON_3846 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 500905 0 0 968673 427949 0 0 0 0 0 0 0 0 631107 0 0 0 0 699457 1461895 0 1047598 0 0 0 0 0 0 0 0 414377 0 0 0 0 473622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQYKTEEGR MGYG000000245_00521;MGYG000004271_00924;MGYG000000271_01230 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM oxidoreductase FAD NAD(P)-binding domain protein 1.0 pyrK_1 1.0 - 1.0 1.18.1.2,1.19.1.1 1.0 ko:K00528,ko:K16951 1.0 ko00920,ko01120,map00920,map01120 1.0 - 1.0 R00858,R10146,R10159 1.0 RC00065 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ferredoxin--NADP(+) reductase. | flavodoxin--NADP(+) reductase. FPR. In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe- 2S] ferredoxins, but in other bacteria it can also reduce bacterial 2[4Fe-4S] ferredoxins and flavodoxin.-!-Formerly EC 1.6.7.1 and EC 1.6.99.4. | This activity occurs in some prokaryotes and algae that possess flavodoxin, and provides low-potential electrons for a variety of reactions such as nitrogen fixation, sulfur assimilation and amino acid biosynthesis.-!-In photosynthetic organisms it is involved in the photosynthetic electron transport chain.-!-The enzyme also catalyzes EC 1.18.1.2. H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]. | NADP(+) + reduced [flavodoxin] = 2 H(+) + NADPH + oxidized [flavodoxin]. 1.0 1.0 1.0 1.0 Sulfur metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAQYNFVGASEQLESAHR MGYG000002515_02888;MGYG000002494_04167;MGYG000002323_03571 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,3XMC8@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 1.0 M 0.6666666666666666 Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells 0.6666666666666666 tolC 1.0 GO:0002790,GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008104,GO:0008150,GO:0009279,GO:0009306,GO:0009987,GO:0010033,GO:0014070,GO:0015031,GO:0015075,GO:0015267,GO:0015288,GO:0015318,GO:0015562,GO:0015688,GO:0015711,GO:0015833,GO:0015850,GO:0015891,GO:0015893,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022838,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032940,GO:0032991,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0042886,GO:0042930,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0046618,GO:0046903,GO:0047485,GO:0050896,GO:0051179,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098796,GO:1901678,GO:1902495,GO:1990195,GO:1990196,GO:1990281,GO:1990351 1.0 - 1.0 ko:K12340 1.0 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 1.0 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.0 1.B.17,2.A.6.2 1.0 - 1.0 iAPECO1_1312.APECO1_3378,iEC042_1314.EC042_3326,iECOK1_1307.ECOK1_3463 1.0 OEP,SPOR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance;Plant-pathogen interaction;Bacterial secretion system;Two-component system;Cationic antimicrobial peptide (CAMP) resistance;Pertussis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 591200 0 0 0 1149384 0 0 0 0 0 0 0 0 0 0 0 0 645778 0 0 1092463 0 1098567 0 0 0 0 746393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QASHLALSASETAQK MGYG000002494_02854 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3WXSN@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 NT 1.0 Homologues of the ligand binding domain of Tar 1.0 tsr 1.0 GO:0001101,GO:0001932,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0006935,GO:0007154,GO:0007165,GO:0007172,GO:0008104,GO:0008150,GO:0009593,GO:0009605,GO:0009719,GO:0009966,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0023051,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031399,GO:0032101,GO:0032110,GO:0032268,GO:0032879,GO:0032991,GO:0033036,GO:0034613,GO:0034622,GO:0038023,GO:0040011,GO:0040012,GO:0042221,GO:0042325,GO:0042330,GO:0042802,GO:0042803,GO:0043113,GO:0043200,GO:0043424,GO:0043549,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0046983,GO:0048583,GO:0048870,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051174,GO:0051179,GO:0051246,GO:0051259,GO:0051260,GO:0051270,GO:0051338,GO:0051606,GO:0051641,GO:0051668,GO:0051674,GO:0051716,GO:0060089,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0070727,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071840,GO:0071944,GO:0072657,GO:0080090,GO:0098561,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902021,GO:2000145 1.0 - 1.0 ko:K03406,ko:K05874,ko:K05875,ko:K05876,ko:K05877 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 4HB_MCP_1,HAMP,MCPsignal,TarH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 425671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 616047 0 0 906677 0 0 0 774067 0 0 0 484603 0 0 754105 0 564134 0 621249 995100 0 788026 762446 0 0 0 646595 946193 0 0 276099 0 0 467438 0 323135 0 0 435670 0 0 0 0 0 0 0 0 0 0 0 0 0 109387 0 0 0 117670 0 0 0 0 0 0 0 0 0 0 0 415526 0 0 0 0 733186 0 0 0 0 0 199770 0 0 0 1365733 0 0 0 0 0 0 1612623 0 0 0 212314 0 0 140896 1293525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 118659 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QASHLAQSASDTAQHGGK MGYG000002494_03457 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3WWBY@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 T 1.0 Homologues of the ligand binding domain of Tar 1.0 tar 1.0 GO:0001101,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006935,GO:0007154,GO:0007165,GO:0007172,GO:0008150,GO:0009593,GO:0009605,GO:0009719,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010243,GO:0010604,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0023051,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032101,GO:0032268,GO:0032270,GO:0032991,GO:0034622,GO:0038023,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042802,GO:0042803,GO:0043200,GO:0043424,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051606,GO:0051716,GO:0060089,GO:0060255,GO:0065003,GO:0065007,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071840,GO:0071944,GO:0080090,GO:0098561,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901873,GO:1901875 1.0 - 1.0 ko:K03406,ko:K05875 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 4HB_MCP_1,HAMP,MCPsignal,TarH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1052142 1145210 1682878 0 1163240 2627517 1318959 650412 950195 1510423 0 0 568571 1182752 655253 893438 1616701 0 1396378 0 1943021 2384751 0 1870759 1619561 775233 0 0 0 2053647 0 0 1728757 1058470 0 930177 688819 1143412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QASQPAAKPGEKPAAPR MGYG000002438_01914 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1082@1|root,COG1082@2|Bacteria,4NFQY@976|Bacteroidetes,2FWU9@200643|Bacteroidia,22ZRC@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Xylose isomerase domain protein TIM barrel 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365755 0 0 0 0 0 0 0 0 212447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278477 0 0 0 0 0 0 0 0 137977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587778 0 0 0 0 0 0 0 0 706987 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QASTFNVPR MGYG000002775_00049;MGYG000002970_01003;MGYG000001718_01539;MGYG000002947_00114;MGYG000002961_01072;MGYG000003266_00425;MGYG000002978_00868;MGYG000002919_00399;MGYG000000802_00739;MGYG000000188_00931;MGYG000004681_00043 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CU9M@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QATAAAVGVSK MGYG000001345_02855;MGYG000002549_01703;MGYG000000196_02098 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia,4ARQC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1344676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1311689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 515428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QATEEDILAIYK MGYG000003683_01043 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CZ71@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 fucO 1.0 - 1.0 1.1.1.77,1.1.99.37,1.2.98.1 1.0 ko:K00048,ko:K17067 1.0 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 1.0 - 1.0 R00614,R01781,R02257 1.0 RC00034,RC00087,RC00099,RC00188 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lactaldehyde reductase. | methanol dehydrogenase (nicotinoprotein). | formaldehyde dismutase. propanediol oxidoreductase. | nicotinoprotein methanol dehydrogenase. Nicotinoprotein methanol dehydrogenases have a tightly bound NADP+/NADPH cofactor that does not dissociate during the catalytic process.-!-Instead, the cofactor is regenerated by a second substrate or electron carrier.-!-While the in vivo electron acceptor is not known, N,N-dimethyl-4- nitrosoaniline (NDMA) can serve this function in vitro.-!-The enzyme has been detected in several Gram-positive methylotrophic bacteria, including Amycolatopsis methanolica, Rhodococcus rhodochrous and Rhodococcus erythropolis.-!-These enzymes are decameric, and possess a 5-fold symmetry.-!-Some of the enzymes can also dismutate formaldehyde to methanol and formate. | Enzyme-bound NADPH formed by oxidation of formaldehyde to formate is oxidized back to NADP(+) by reaction with a second formaldehyde, yielding methanol.-!-The enzyme from Mycobacterium sp. DSM 3803 also catalyzes the reactions of EC 1.1.99.36 and EC 1.1.99.37.-!-Formaldehyde and acetaldehyde can act as donors; formaldehyde, acetaldehyde and propanal can act as acceptors.-!-Formerly EC 1.2.99.4. (1) (R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + H(+) + NADH. (2) (S)-propane-1,2-diol + NAD(+) = (S)-lactaldehyde + H(+) + NADH. | A + methanol = AH2 + formaldehyde. | 2 formaldehyde + H2O = formate + H(+) + methanol. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Chloroalkane and chloroalkene degradation;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QATFEEMIAR MGYG000003883_02162;MGYG000002494_01839;MGYG000002506_02873;MGYG000002515_03108;MGYG000002323_00471;MGYG000003372_02670;MGYG000002366_00531;MGYG000003365.1_03992 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,3XP67@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly 1.0 rplM 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02871 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 188212 0 146506 97992 0 321227 121844 0 93066 0 0 0 0 0 0 0 0 0 0 117416 114478 494527 0 266285 64154 0 0 0 0 0 0 87889 0 216648 0 118693 225575 191568 444166 546590 546975 479441 449966 825409 656497 466543 376216 0 0 0 342643 699983 624204 390085 0 0 0 522626 667440 1089322 0 902914 662706 431215 459917 0 666435 0 0 548402 449450 399402 396072 495390 311864 385185 108738 76581 253857 0 307235 351061 202930 196674 296764 0 0 0 108762 244076 204264 159861 0 0 0 233349 207676 337306 0 463987 223947 98455 108163 0 111610 0 0 194318 115730 125120 131224 248001 0 126223 293516 166961 225576 226335 88342 249791 255241 257254 136923 0 0 0 157263 235809 196470 214686 0 0 0 116441 274479 309803 0 92102 282478 312363 114964 0 119144 0 0 266873 277562 407773 312996 254563 127731 231009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QATKDAGKIAGLDVK MGYG000000200_01023;MGYG000000002_00433;MGYG000000255_01223;MGYG000002720_01392;MGYG000002926_00096;MGYG000002989_00635;MGYG000000245_00866;MGYG000000187_00181;MGYG000000262_01374;MGYG000000271_02474;MGYG000001310_00050;MGYG000001319_00507;MGYG000001315_00535;MGYG000000142_01918;MGYG000004733_01142;MGYG000004740_00081;MGYG000000251_02358;MGYG000000127_03199;MGYG000002279_01669;MGYG000000164_00503;MGYG000000562_02511;MGYG000002972_00261;MGYG000004879_00274;MGYG000000153_02121;MGYG000002517_00989;MGYG000004271_00836;MGYG000002042_00970 domain d__Bacteria 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.3333333333333333 186801|Clostridia 0.9629629629629629 O 1.0 Heat shock 70 kDa protein 0.9259259259259259 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 0.9629629629629629 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QATKDAGKIAGLDVKR MGYG000000200_01023;MGYG000000002_00433;MGYG000000255_01223;MGYG000002720_01392;MGYG000002926_00096;MGYG000002989_00635;MGYG000000245_00866;MGYG000000187_00181;MGYG000000262_01374;MGYG000000271_02474;MGYG000001310_00050;MGYG000001319_00507;MGYG000001315_00535;MGYG000000142_01918;MGYG000004733_01142;MGYG000004740_00081;MGYG000000251_02358;MGYG000000127_03199;MGYG000002279_01669;MGYG000000164_00503;MGYG000000562_02511;MGYG000002972_00261;MGYG000004879_00274;MGYG000000153_02121;MGYG000002517_00989;MGYG000004271_00836;MGYG000002042_00970 domain d__Bacteria 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.3333333333333333 186801|Clostridia 0.9629629629629629 O 1.0 Heat shock 70 kDa protein 0.9259259259259259 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 0.9629629629629629 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QATKEAGEIAGLK MGYG000004756_00370;MGYG000000003_01212;MGYG000001302.1_00819;MGYG000001562_02334;MGYG000000170_00600 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,22UA3@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QATKEAGQIAGLEVK MGYG000004876_01872;MGYG000001346_01172;MGYG000000196_01218;MGYG000000243_00100;MGYG000002478_02522;MGYG000002171_02941 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,4ANVI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QATKEAGQIAGLEVKR MGYG000004876_01872;MGYG000001346_01172;MGYG000000196_01218;MGYG000000243_00100;MGYG000002478_02522;MGYG000002171_02941 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,4ANVI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QATKGEVVSHIASDNVLGGK MGYG000002506_03421 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,3XN9E@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Part of the ABC transporter complex RbsABC involved in ribose import. Probably responsible for the translocation of the substrate across the membrane 1.0 rbsC 1.0 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015591,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 1.0 - 1.0 ko:K10440 1.0 ko02010,map02010 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 iAF1260.b3750,iAPECO1_1312.APECO1_2713,iB21_1397.B21_03581,iBWG_1329.BWG_3441,iE2348C_1286.E2348C_4060,iEC042_1314.EC042_4137,iEC55989_1330.EC55989_4225,iECABU_c1320.ECABU_c42350,iECBD_1354.ECBD_4280,iECB_1328.ECB_03636,iECDH10B_1368.ECDH10B_3938,iECDH1ME8569_1439.ECDH1ME8569_3638,iECED1_1282.ECED1_4440,iECH74115_1262.ECH74115_5186,iECIAI1_1343.ECIAI1_3934,iECNA114_1301.ECNA114_3899,iECO103_1326.ECO103_4407,iECO111_1330.ECO111_4584,iECO26_1355.ECO26_4828,iECOK1_1307.ECOK1_4199,iECS88_1305.ECS88_4172,iECSE_1348.ECSE_4040,iECSF_1327.ECSF_3598,iECSP_1301.ECSP_4800,iECUMN_1333.ECUMN_4280,iECs_1301.ECs4692,iEcDH1_1363.EcDH1_4217,iEcE24377_1341.EcE24377A_4266,iEcHS_1320.EcHS_A3966,iEcSMS35_1347.EcSMS35_4118,iEcolC_1368.EcolC_4244,iJO1366.b3750,iJR904.b3750,iLF82_1304.LF82_1817,iNRG857_1313.NRG857_18675,iUMN146_1321.UM146_18940,iUMNK88_1353.UMNK88_4562,iUTI89_1310.UTI89_C4305,iY75_1357.Y75_RS18320,ic_1306.c4678 1.0 BPD_transp_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 449713 0 375710 306430 0 564373 0 0 0 412632 0 0 0 0 0 0 0 0 0 0 259421 0 0 0 0 415027 0 0 0 529226 0 0 0 0 0 0 0 0 0 0 0 164446 0 304136 0 0 0 185214 0 0 0 0 0 0 0 0 0 0 241430 0 0 0 0 397362 0 0 0 410241 0 0 0 0 0 0 0 0 657662 0 576300 598872 0 667535 0 0 0 343026 0 0 0 0 0 0 0 0 0 0 781367 0 0 0 0 365406 0 0 0 1116532 0 0 0 0 0 0 0 0 559038 0 653020 772250 0 1060264 0 0 0 715703 0 0 0 0 0 0 0 0 0 0 966720 0 0 0 0 949725 0 0 0 1107542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QATQGLANWVK MGYG000001338_03091;MGYG000000002_03130;MGYG000002312_00094;MGYG000000038_02498;MGYG000000251_02538;MGYG000003937_00291;MGYG000000262_02904;MGYG000000084_01848;MGYG000000249_02227;MGYG000000195_00356;MGYG000002212_01534;MGYG000002772_00865;MGYG000003921_01064;MGYG000000200_01731;MGYG000003291_00397;MGYG000002040_00491;MGYG000000022_00865;MGYG000001315_01504;MGYG000004712_00027;MGYG000000909_02129;MGYG000001619_02390 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia 0.47619047619047616 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 0.47619047619047616 pgcA 1.0 - 1.0 5.4.2.2,5.4.2.8 1.0 ko:K01835,ko:K01840 1.0 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00114,M00549 1.0 R00959,R01057,R01818,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). | phosphomannomutase. phosphoglucose mutase. | phosphomannose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. | alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. | alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458004 0 0 0 0 340222 0 0 0 0 247445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259436 0 0 0 0 433525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342557 0 0 0 0 635275 0 0 0 0 723344 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAVENDVHVMGVSSLAAGHK MGYG000002438_02292 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,22WFX@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 412501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390360 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 729604 0 622260 0 0 0 0 0 0 -(Gln->pyro-Glu)QAVGARPK MGYG000001300_02313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3WJWZ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Belongs to the thioredoxin family 1.0 trxA 1.0 - 1.0 - 1.0 ko:K03671 1.0 ko04621,ko05418,map04621,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 Thioredoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Fluid shear stress and atherosclerosis;NOD-like receptor signaling pathway 1.0 none 1.0 0 0 0 0 0 121996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304908 0 0 0 0 270094 0 0 0 0 0 0 0 0 0 0 470762 0 226741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342554 0 0 0 0 208422 0 0 0 0 0 0 0 0 0 0 237623 0 273716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 977803 0 0 0 0 923874 0 0 0 0 0 0 0 0 0 0 990970 0 1413654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79991 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 411570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAVKPVEVK MGYG000002492_00606 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1294768 0 0 0 0 934795 0 0 0 0 1400907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1618550 0 0 0 0 1719412 0 0 0 0 2125924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAVMYALDTEK MGYG000002919_00279;MGYG000002947_01121;MGYG000003122_01785;MGYG000004681_01414;MGYG000003096_01010;MGYG000001718_00608;MGYG000001086_01015;MGYG000004746_01539 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0747@1|root,COG0747@2|Bacteria,2GK4Y@201174|Actinobacteria,4CUGK@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Tat pathway signal sequence domain protein 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 479000 0 0 0 0 0 0 0 0 0 0 0 0 0 320227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150890 0 0 0 0 0 0 0 0 237716 0 0 0 0 0 0 0 0 0 0 0 0 0 270331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199302 0 0 0 0 0 0 0 0 708850 0 0 0 0 0 0 0 0 0 0 0 0 0 582427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331083 0 0 0 0 0 0 0 0 432733 0 0 0 0 0 0 0 0 0 0 0 0 0 898834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 752459 0 0 0 0 0 0 0 0 813535 0 0 0 0 0 0 0 0 0 0 0 0 0 355329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 645305 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAVPLLRTEAPIVGTGIEK MGYG000000243_01980;MGYG000004763_01697;MGYG000002478_00806 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,2FMDI@200643|Bacteroidia,4AKI0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAVTNADKTISSIKR MGYG000002276_02250;MGYG000004087_01928;MGYG000003355_02854;MGYG000001698_00974;MGYG000000139_01467;MGYG000004869_03374;MGYG000002989_00635;MGYG000000562_02511;MGYG000000179_03775;MGYG000001689_04245;MGYG000000187_00181;MGYG000000262_01374;MGYG000000287_03181;MGYG000000198_01270;MGYG000003427_02364;MGYG000001652_01558 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.25 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 500399 0 340731 0 0 0 0 170701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228570 0 0 0 195342 0 0 0 0 145161 0 441231 0 0 0 0 0 0 447355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 972457 0 0 0 0 0 0 0 0 0 0 1160711 0 720825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 557698 1174007 1499914 0 0 0 0 1127044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1307813 0 0 0 1121294 0 0 0 0 886596 -(Gln->pyro-Glu)QAVTNADRTISSIKR MGYG000000142_01918;MGYG000004733_01142;MGYG000000255_01223 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAVTNAEKTISSIKR MGYG000004740_00081;MGYG000000153_02121;MGYG000000245_00866;MGYG000002517_00989;MGYG000000271_02474;MGYG000001315_00535;MGYG000004271_00836;MGYG000000002_00433;MGYG000000164_00503 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 0.5555555555555556 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAVTNPQNTLFAIKR MGYG000002494_02915;MGYG000002323_00619;MGYG000002506_04145;MGYG000002515_00010 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,3XM30@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 1440029 0 0 0 0 625780 0 1168026 960628 1348531 1191538 1636117 0 478309 0 0 0 0 927392 0 0 906450 0 0 0 980340 1283124 0 0 0 0 688301 0 925646 1274203 663027 0 0 1647228 0 0 0 0 2225953 2212880 1434306 1894529 1424170 552261 1628038 0 2660865 0 0 0 0 3712746 0 0 0 0 2305667 0 711813 1889925 0 0 0 1634560 1957725 0 1687655 1408964 1937061 1695653 0 906474 0 0 0 0 871691 911192 839631 498670 1262238 0 812584 0 492631 0 0 0 0 0 0 0 1078122 0 753077 0 1173257 656403 0 0 0 557799 901456 0 771709 0 801113 567406 0 619809 0 0 0 0 331116 0 482166 591833 0 948333 0 0 688248 0 0 0 0 0 0 0 587177 0 0 0 401792 728436 0 0 0 447133 477060 0 667568 0 684739 575162 0 0 0 0 0 0 523166 375536 1282458 0 697841 496261 0 0 0 0 0 0 0 349270 0 0 450092 0 609035 0 0 598198 0 0 0 0 0 0 804928 526961 508436 0 0 -(Gln->pyro-Glu)QAVTNVDR MGYG000002943_00903;MGYG000001292_00143;MGYG000001283_01100;MGYG000001443_05092;MGYG000003452_00557;MGYG000000111_01884;MGYG000003683_01758;MGYG000000756_01483 class d__Bacteria|p__Actinobacteriota|c__Actinomycetia 1.0 COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CZDX@85004|Bifidobacteriales 0.625 201174|Actinobacteria 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679 0.75 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl,TIR_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 689711 0 0 0 0 396615 0 0 0 0 613969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAYALNINYSATQRQ MGYG000000243_02199;MGYG000002171_02038 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,2FM42@200643|Bacteroidia,4APFS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 COG NOG14448 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K03559 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 ExbD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461910 0 0 0 0 410076 0 0 286152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 373239 0 0 0 0 258272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAYDC(Carbamidomethyl)LTHGLTTVC(Carbamidomethyl)EIGR MGYG000001636_00244;MGYG000002050_00004;MGYG000003266_01688;MGYG000002065_00521;MGYG000001642_00469 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4CXAV@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 Q 1.0 Amidohydrolase family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 823344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QAYILQNEDKR MGYG000002494_02083 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family 1.0 glpD 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004368,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006072,GO:0006091,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009331,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016901,GO:0019637,GO:0022900,GO:0031224,GO:0031226,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046168,GO:0046434,GO:0048037,GO:0050660,GO:0050662,GO:0052590,GO:0052646,GO:0055114,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:1901135,GO:1901136,GO:1901265,GO:1901363,GO:1901575,GO:1902494,GO:1990204 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iSSON_1240.SSON_3663 1.0 DAO,DAO_C 1.0 - 1.0 - 1.0 - 1.0 GH36 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156766 0 0 0 0 0 0 0 0 0 0 0 0 552854 0 0 0 0 0 0 0 0 498979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 617725 566304 0 0 0 0 0 0 0 0 0 541723 0 0 0 0 0 0 0 0 0 0 754295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 451651 816719 0 0 0 0 0 0 0 0 0 0 0 498363 0 0 0 0 0 0 0 0 150019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174051 636281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QC(Carbamidomethyl)EAEETTK MGYG000000997_00886;MGYG000000245_00417;MGYG000000164_00893;MGYG000002517_01841;MGYG000004271_02055;MGYG000000271_00295 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 344621 976216 687317 613187 753054 0 518118 441939 544578 355326 338251 287487 0 623427 531642 0 459436 0 321688 633361 644393 658211 0 0 847442 0 0 0 538094 0 831635 629537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754458 0 0 996023 0 0 352108 975947 703870 492950 448144 372973 309730 795030 953652 366593 611535 0 300413 600074 0 0 0 0 1338604 1171139 1302628 0 0 656457 0 422270 377304 960205 1023134 1191079 946451 0 664781 0 598640 0 0 900958 162216 501310 727256 850972 959971 598429 1334528 742780 1111936 949106 1005901 0 860566 744458 0 534694 0 713961 928226 1050735 862014 0 0 868636 0 347652 740926 850973 917274 808456 1528423 896689 -(Gln->pyro-Glu)QC(Carbamidomethyl)KGEGETAK MGYG000000013_01972;MGYG000002478_01954;MGYG000001378_04028;MGYG000002935_01218;MGYG000001750_00043;MGYG000004763_02063;MGYG000001346_03576;MGYG000000243_02666;MGYG000001783_00760;MGYG000002549_04091;MGYG000001835_00524;MGYG000001345_03177;MGYG000004479_00322 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,2FPZE@200643|Bacteroidia,4AKS9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another 1.0 frr 1.0 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02838 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 RRF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 505236 0 679150 611673 635822 495162 519358 505250 0 468780 832317 405882 0 0 0 0 0 0 0 426791 678793 644728 0 602477 656040 600151 592907 0 0 0 0 344026 832628 0 0 0 537800 842781 406515 0 533511 590385 608253 537719 394155 659627 0 465560 1067577 785436 0 0 0 0 0 0 0 395047 281640 526547 0 405864 490336 582368 542411 0 0 0 0 567986 315748 0 0 0 393170 465277 104197 0 277844 126428 281178 274911 65839 79636 0 151088 289988 184578 0 0 0 0 0 0 0 305968 71860 181362 0 341130 221153 101121 331441 0 0 0 0 274916 209431 0 0 0 209511 189198 207208 0 211893 263186 164786 0 295969 201757 0 109275 179246 194184 0 0 0 0 0 0 0 190748 0 126846 0 0 256558 347363 270960 0 0 0 0 107681 0 0 0 0 216596 104990 104481 0 139405 214151 249551 193771 198552 0 0 171972 279286 255568 0 0 0 0 0 0 0 210429 0 225278 0 215798 0 190744 66127 0 0 0 0 0 116286 0 0 0 298393 223348 -(Gln->pyro-Glu)QC(Carbamidomethyl)SIGVTAR MGYG000000003_01141;MGYG000001302.1_00873;MGYG000003952_01072 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG2066@1|root,COG2066@2|Bacteria,4NERJ@976|Bacteroidetes,2FM3D@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the glutaminase family 1.0 glsA 1.0 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.0 3.5.1.2 1.0 ko:K01425 1.0 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 1.0 - 1.0 R00256,R01579 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glutaminase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaminase. L-glutamine amidohydrolase. - H2O + L-glutamine = L-glutamate + NH4(+). 1.0 1.0 1.0 1.0 GABAergic synapse;Proximal tubule bicarbonate reclamation;Central carbon metabolism in cancer;Arginine biosynthesis;Metabolic pathways;MicroRNAs in cancer;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse 1.0 none 1.0 0 0 0 1083684 0 0 948483 0 915118 0 0 0 0 1092737 0 0 0 0 0 0 1518069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1295586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QC(Carbamidomethyl)SLGVTAR MGYG000000003_01141;MGYG000002007_00949 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG2066@1|root,COG2066@2|Bacteria,4NERJ@976|Bacteroidetes,2FM3D@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the glutaminase family 1.0 glsA 1.0 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.0 3.5.1.2 1.0 ko:K01425 1.0 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 1.0 - 1.0 R00256,R01579 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glutaminase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaminase. L-glutamine amidohydrolase. - H2O + L-glutamine = L-glutamate + NH4(+). 1.0 1.0 1.0 1.0 GABAergic synapse;Proximal tubule bicarbonate reclamation;Central carbon metabolism in cancer;Arginine biosynthesis;Metabolic pathways;MicroRNAs in cancer;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1376910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDAADAATAVEGGM(Oxidation)YQALK MGYG000002438_00802 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,22WD0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 803186 0 0 0 0 0 0 0 0 847936 0 0 0 0 0 0 0 0 649901 0 401045 0 0 0 0 0 0 0 699917 0 0 0 0 0 0 0 0 0 667975 0 0 0 0 0 0 0 0 669222 0 0 0 0 0 0 0 0 441629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 574707 0 0 1557911 528128 0 0 0 0 0 1735594 1320535 0 0 0 0 1096815 0 0 2740355 490897 993276 1064791 0 0 0 778403 0 2669444 0 1681885 0 0 0 0 0 0 -(Gln->pyro-Glu)QDAAPAQTEQTTEAAVVEEGGGLHK MGYG000002478_02040;MGYG000004797_01477 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 10123621 8347296 6771949 15163203 9366193 0 15632073 6462576 12671670 9593421 0 10367084 9985033 8901924 9421787 12308752 9893782 8593017 9349244 9362224 0 9385307 14405064 0 11620533 12331470 12242496 12763877 12843494 0 13184713 10749866 8120197 4624403 0 14892570 9575807 7198368 10440364 6024302 8689673 13105201 12117196 11750321 9475108 13764364 10385627 10357881 17098365 9861428 18399624 13276632 13571209 20616360 9665170 7942920 12635638 9607932 11316892 10305498 8068655 8123936 10791422 12390135 11691975 6752119 10671397 11062699 8355615 10803966 9668049 6751782 0 8609047 10571625 8619471 6507082 4715417 6468598 5926459 8779407 6991292 9024762 5095902 9694021 5819302 6438836 7899775 8027918 6098856 5509149 7406913 5654420 11291755 6251765 5275005 5754398 5103355 8818630 6130804 5795171 7376385 5742143 11514493 6886158 5317933 9241207 3819772 4452939 3421210 0 7488233 7646597 5560098 2388711 1430016 1715728 865677 1599229 1618759 1855478 2032565 1751477 2021630 1470982 1845218 2414682 2018692 1786966 352034 1854563 1008901 2182536 2022154 2332851 1555202 309466 1359159 318545 1762938 1834838 763156 1989962 0 238959 1682477 1682646 942328 0 2863149 2111930 1900241 13048597 8857772 6889471 9066833 21713466 11770632 12237733 13661363 13389845 4787464 9832735 8146071 20410932 9569924 10794707 19439544 10474894 0 12925215 15186052 7359048 10150286 0 11791927 13190434 15346805 12491069 0 13197649 12645921 8908169 12036027 7842275 11871374 0 12197516 13822834 10525067 -(Gln->pyro-Glu)QDAAPAQTEQTTEAAVVEEGGGLHKELK MGYG000002478_02040;MGYG000004797_01477 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 6062212 6500718 14899316 7290078 14106018 6906359 6423798 7646234 7165461 7206946 7810877 7218170 13885093 9182894 4471225 9611928 8450363 5348013 7661160 5852852 5037943 6770523 4578887 7603212 6327900 8548069 5897192 7273271 426695 8980544 16129467 1004981 11272635 2873264 0 5183343 8331770 9895077 1148938 1001548 1076345 1296682 3721538 1437235 1081399 1269367 914893 1703869 2621523 882753 4335133 1338918 2192502 2131964 1636073 0 899620 1010964 1179711 1769995 0 1137464 1424694 1114635 1601475 0 2197456 1275991 1272721 3519491 1558781 775881 0 1245527 1258088 1409033 3033306 3650292 4604448 5355271 5227142 5183453 2589685 3455718 3237350 4234332 3663016 4241942 6209467 2684314 2198452 4541014 3352291 3733128 2444564 2605536 2217087 2400300 2902940 3633417 2798974 3615889 2279237 2338131 3806083 2802374 3971784 3716302 3200619 1840269 0 3076764 4154706 2892807 997274 473886 1191879 1203745 741545 1154633 756671 1356103 1011819 1417862 669304 941477 1346251 816212 1458666 879473 557077 836462 1668088 791467 1122100 1015906 653330 736864 1065180 1171223 1239580 829517 790095 1056484 713004 806352 984216 720852 0 1034307 561715 883463 2540697 2633440 3670973 6993780 8533535 6112452 2225135 2202673 4194312 2642472 4954862 3635050 15199088 2952972 2368358 4846027 3906617 965275 3822522 2743914 1292188 3665413 898646 4407882 2700417 3725924 3187377 1087617 5047419 3123676 5484449 5647460 4475667 2143643 0 3782140 9928250 5927193 -(Gln->pyro-Glu)QDAKPEEGFVFTTVK MGYG000000196_04371 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia,4AKZY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase C1-like family 1.0 pepC 1.0 - 1.0 3.4.22.40 1.0 ko:K01372 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_C1,Peptidase_C1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 bleomycin hydrolase. aminopeptidase C (Lactococcus lactis). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain.-!-Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity.-!-Known from bacteria as well as eukaryotic organisms.-!-Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates.-!-Belongs to peptidase family C1. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 1030814 0 0 979509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1338888 0 0 0 0 0 0 0 0 1646690 0 0 1404440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1340167 0 0 0 0 0 0 0 0 995436 0 0 495997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 865611 0 0 0 0 0 0 0 0 664738 0 0 561793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545764 0 0 0 0 0 0 0 0 586372 0 0 392082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239284 0 0 -(Gln->pyro-Glu)QDAPAAEQTEQAAPAAQAAPADEAAAPVVAEEGGIHK MGYG000003681_00101 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3504456 1284812 2423272 5021798 2463381 0 3972434 5654383 3876042 5039955 0 0 0 5798455 5904859 0 3553773 0 4931262 4837046 4639455 0 0 0 5646424 5588508 5381936 0 3477748 5404629 2649729 2915321 2438423 3737211 4752946 3457610 4013178 3199467 841856 422189 792690 1047905 1024683 0 1416484 727938 1201369 948026 0 0 0 1051652 869658 0 1071442 0 926684 689745 125651 0 0 0 153722 1179370 819002 0 1151046 265375 999761 491261 228919 653107 866857 1074747 1038843 379274 740636 650156 728034 295492 862873 0 1147024 275356 1141359 291332 0 0 0 568330 859698 0 869360 0 1238291 1018480 1051537 0 0 0 630997 906677 346219 0 1065783 1042511 432015 664562 748566 1400147 956097 997854 393022 1025541 0 0 0 0 0 0 403975 372859 296150 0 0 0 0 0 171485 0 375013 0 0 0 274377 0 0 0 146430 546740 200040 0 0 522784 0 0 0 320297 699987 284572 469272 0 -(Gln->pyro-Glu)QDAPAAEQTEQAAPAAQAAPADEAAAPVVAEEGGIHKEIK MGYG000003681_00101 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1017326 0 0 0 711440 1125609 0 0 0 0 0 0 0 0 0 0 0 672188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 548085 0 0 0 289832 263601 0 0 0 0 0 0 0 0 0 0 0 543983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 569582 0 0 0 316395 649429 0 0 0 0 0 0 0 0 0 0 0 495601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDAPAAEQTEQAAPAAQAAPADEVAAPAVEAEEGGIHK MGYG000001313_03230 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1788708 0 1335192 0 0 1830438 2332456 1251059 2131685 1758477 0 0 1091194 0 1654763 0 2001773 5027607 1224988 0 0 1163159 4273103 2031025 0 2287082 1347070 3274839 1858824 0 2224170 1155392 1243366 1673642 1654922 2274336 2001489 1630122 336193 0 495492 0 0 452820 515071 293752 261748 405113 0 0 610933 0 455631 0 298883 0 426211 0 0 519978 0 0 0 492464 522412 0 191765 0 297496 340107 172232 220931 369075 495031 466863 443095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDAPAAEQTEQAAPAAQAAPADEVAAPAVEAEEGGIHKEIK MGYG000001313_03230 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1008709 0 1647525 0 0 1728740 0 1370070 1210871 1265912 0 0 1121537 0 0 0 1491881 2156816 0 0 0 1047257 1365547 1422156 0 1531904 0 1838381 0 0 1594571 1126946 912216 0 0 1194974 1016189 1167213 293786 0 239398 0 0 346516 0 183102 243279 304285 0 0 298360 0 0 0 129216 0 0 0 0 268474 0 0 0 298179 0 0 0 0 0 171198 216125 0 0 318460 174190 335960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDAPAAEQTEQAAPAAQAAPAGDATVEAEEGGIHK MGYG000001780_00327;MGYG000002455_01561 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 882037 0 0 1289853 0 466264 1138252 0 0 0 0 0 753720 0 826779 0 0 546666 0 0 0 757105 782573 1081858 807984 984992 977075 570211 1108400 0 902565 0 0 1441133 749467 0 787685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 434278 0 0 602308 0 0 715864 0 0 0 0 0 581989 0 618306 0 0 380783 0 0 0 321458 638452 292651 0 475736 461498 0 637234 0 275455 0 0 473994 531883 0 623801 0 1674966 0 0 1023348 0 1447952 2310946 0 0 0 0 0 2527465 0 1581100 0 0 9251856 0 0 0 1160269 6862909 1587107 2682415 2967624 2386554 6781342 1105035 0 1004045 0 0 3542924 2662103 0 2253015 0 -(Gln->pyro-Glu)QDAPAAEQTEQAAPAAQAAPAGDATVEAEEGGIHKEIK MGYG000001780_00327;MGYG000002455_01561 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 819499 0 962809 800753 986862 0 433760 1144448 0 0 0 1155846 526051 0 0 0 0 200863 874890 0 0 0 554659 0 0 734581 0 493127 0 0 0 0 822171 1080038 0 0 386420 710863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1312576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280094 0 578368 557259 538870 0 336728 907170 0 0 0 354757 319245 0 0 0 0 536904 945136 0 0 0 0 0 0 602275 0 609345 0 0 0 0 493948 542296 0 0 359404 507173 578042 0 798759 1354902 890041 0 798282 587618 0 0 0 691867 2180407 0 0 0 0 647375 837155 0 0 0 854007 0 0 1085606 0 809878 0 0 0 0 859860 1436213 0 0 1749459 1051534 -(Gln->pyro-Glu)QDAPAAEQTEQAAVAPAADAAAPAAMEAAEGGIHK MGYG000001346_00886 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 439339 0 0 0 0 0 464929 449339 314864 467433 1211713 635403 0 478702 349375 250424 388662 0 0 344860 444638 0 558335 454829 0 452361 386320 396630 0 0 457930 317848 0 416866 322672 451916 419781 0 1378080 0 1192805 0 1282303 1557530 1515931 1952846 1205982 2249794 2163723 4557516 0 1982588 2064573 293258 1630941 592320 0 1723983 2120572 1906300 353189 544061 0 2076745 1787536 413443 0 0 1088762 1574798 1365921 1368279 1358984 1221316 1221981 1011653 1330048 0 1385918 0 1796408 1164072 2018422 1427390 1618554 1313569 2804495 1912155 0 1266174 1414997 1565605 1521213 3291157 0 1215227 1677316 1151188 2756962 1440155 0 1636930 1307708 2108435 0 0 1536936 988773 1259301 629733 1346858 1701062 1207108 1196988 1014037 0 353812 0 1012037 777872 858005 843925 976055 955945 1373488 1414816 0 749952 672064 861043 878995 739307 0 864266 1198276 730082 799876 782045 0 1015472 852554 440364 0 0 925189 866394 452964 934565 818404 1093912 968745 735865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDAPAAEQTEQAAVAPAADAAAPAAMEAAEGGIHKELK MGYG000001346_00886 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 367898 0 230233 0 231647 0 0 0 1061151 0 0 0 0 0 0 0 0 0 0 0 269650 0 0 0 0 389275 0 0 0 0 362593 0 0 0 0 269458 0 0 307878 0 404732 0 332792 0 0 0 503990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308279 0 0 0 0 287162 0 0 1337419 0 1141263 0 880627 0 0 0 2250306 0 0 0 0 0 0 1403088 0 0 0 0 934138 0 0 0 0 1110423 0 0 0 0 925310 0 0 0 0 1001022 0 0 947095 0 691800 0 497187 0 0 0 1042138 0 0 0 0 0 0 329097 0 0 0 0 643148 0 0 0 0 825824 0 0 0 0 292181 0 0 0 0 413395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDAPAAEQTEQQAAPAAAQAAPAAAPAAEEGGIHK MGYG000000196_02323 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2267495 2077508 1453130 3358649 1409453 1565911 3442746 2119417 2695982 2457170 1156397 2343770 1272922 1743083 2598854 1519463 2195424 0 1939769 1966381 2379850 1687419 0 2681566 2183376 2784240 3220315 0 3627373 3447074 2732326 2202277 1417087 2892297 2093402 3246255 2468397 1286016 1048779 792181 1026604 1592000 1019325 1053038 1107615 1269853 1070692 1550729 1130132 1071384 240622 1368286 1234447 1114979 1188580 0 1310823 1460246 1302553 1236850 0 1079673 149716 1425999 1273046 0 1347927 1374766 869643 1284979 961999 1102141 931115 1049711 1251664 694370 1190390 942919 1022173 1603508 1561960 1111750 1963579 867142 1506419 765424 981722 1364682 809801 1285617 1093868 980440 1178672 0 938998 938531 1366382 789054 0 1189081 1024837 1656604 1147727 0 1101699 1207887 1072731 884920 887872 1119306 1084774 1647111 1288770 1185906 559590 603890 657405 497860 635560 339653 804292 461523 435098 281885 468607 491940 792415 375810 790949 507966 663374 0 386904 213326 841973 414098 0 490978 347722 448017 211358 0 351178 670337 191655 284031 358632 988103 628276 436723 402030 379187 1319411 1067565 1086829 1162138 1066763 1184714 1785879 2364152 1709664 1094867 850876 1120668 1478552 1529406 1187581 1089116 1117043 0 946423 1814756 1126467 1121907 0 1414348 2405270 2206337 2024824 0 1036182 1826456 844637 1128374 913853 2201223 2568864 1697906 1903585 1023872 -(Gln->pyro-Glu)QDAPAAEQTEQQAAPAAAQAAPAAAPAAEEGGIHKEIK MGYG000000196_02323 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1653798 2285092 2096313 1896402 1731471 1877681 1645880 1836239 1673882 1822520 1114882 1625507 1380017 1861101 1768751 1898594 2640635 0 1481499 1628082 1484034 1421597 0 1817726 1255930 1604995 1518638 0 1964100 1890642 2424390 2832291 1963636 1787105 1705925 1671972 1600227 1431129 203127 132845 129110 117558 384441 446878 267069 80451 116543 306504 202194 252565 248488 184992 492325 256345 380134 0 369292 91142 389851 291894 0 264402 271044 207639 297147 0 216795 259006 463457 583720 265470 432706 139835 227391 114464 250326 666560 948721 1432968 1328321 1497242 1105249 1052790 1240828 1449193 742297 722111 1193680 689026 900082 972562 756780 816718 0 767896 891004 958062 589956 0 1231359 1012414 881312 1263244 0 1167959 1435346 1254346 902177 691080 1078684 1326792 903013 1210032 966800 168875 350126 490962 486306 382578 446285 181310 507542 673514 275263 561450 373124 242275 752834 880305 459028 431023 0 458064 390957 606684 391970 0 630356 1014961 671594 1041854 0 418289 476508 461090 599707 285788 1548419 499734 325913 868161 453951 326201 261961 506971 1712371 691690 657057 475408 501425 1782448 1223611 1217990 739622 1965413 527798 689295 392455 512139 0 0 357988 456550 373732 0 578864 803649 1196957 496721 0 762212 532869 940839 868642 279728 1474136 975715 952871 2155583 1410713 -(Gln->pyro-Glu)QDAPAAEQTEQQAAPAAEATTAAAPAAEEGGIHK MGYG000001345_03404;MGYG000002549_04269 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2742856 0 1459660 3763870 1560595 2124345 4781579 3028357 4072717 3187950 5279588 2961604 1304899 2667245 3480487 1919472 2188247 0 2737626 0 0 2213637 0 4211161 0 3445951 3500402 0 0 3897900 2641307 0 1300969 0 2824593 3949308 2773939 1096234 3197410 0 2335048 3496740 1981219 2201686 2709656 3539896 3031267 3779975 7912781 4022419 265075 3809023 4210377 2587815 3060880 0 3414336 0 0 2093061 0 2205448 0 4104772 3605561 0 0 3763368 1598711 0 1767718 0 2669050 2589234 3268953 2779210 1316728 0 1962003 1269003 2111107 1231329 1841324 1013159 1478725 1294787 3003614 1507716 1294332 1125490 1267782 1418247 1151886 0 931382 0 0 895156 0 1335314 0 1615470 1073364 0 0 1152117 1484725 0 1634429 0 1142943 1550938 1156642 1851819 510113 0 1205028 1231325 1321108 1200276 1544297 1371413 1204295 1412560 2532274 1356266 1789647 1241712 1225653 1348531 429425 0 617031 0 0 944829 0 1310708 0 1267174 1333127 0 0 1581986 656273 0 348570 0 1460328 541834 1485138 1398188 1660048 0 1298460 1521338 2644653 4734187 1922840 1746411 2604440 1541182 3437668 1659961 2555897 2138818 1836310 2498947 2596653 0 1534794 0 0 4613623 0 5363546 0 3536200 2715411 0 0 2606367 1549965 0 1498802 0 2462568 2248160 2719925 1914712 -(Gln->pyro-Glu)QDAPAAEQTEQQAAPAAEATTAAAPAAEEGGIHKEIK MGYG000001345_03404;MGYG000002549_04269 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2158701 0 2557474 0 3034431 1917760 0 3722411 2511598 3446779 6356493 2957230 2113434 0 2009739 0 0 0 2352356 0 0 1703141 0 2762718 0 3222565 0 0 0 3229014 3150435 0 1971663 0 2691766 0 2461833 1540556 913058 0 639788 0 835037 371291 0 666378 779870 881725 2541572 539673 876222 0 1403428 0 0 0 498522 0 0 756293 0 545172 0 840732 0 0 0 810545 490420 0 680189 0 773656 0 878646 912078 767259 0 1881636 0 1677665 1080568 0 704325 1282691 805054 1749947 736041 877142 0 526444 0 0 0 478264 0 0 612009 0 1016459 0 820910 0 0 0 718168 1123750 0 1150318 0 222647 0 865524 1444174 1117136 0 1286045 0 1191913 1344253 0 1542472 1145346 1543244 1780273 1334724 1519857 0 1331967 0 0 0 1155933 0 0 1553011 0 875446 0 1262673 0 0 0 1159888 1125833 0 1487958 0 1318633 0 1329845 1019812 751227 0 904875 0 1580094 2942569 0 548171 939403 1108457 4402280 1005608 2817086 0 552392 0 0 0 500449 0 0 3103765 0 3866916 0 1327604 0 0 0 1380716 1500989 0 1156029 0 1657126 0 3469709 1659887 -(Gln->pyro-Glu)QDAPAAEQTEQQAAPAAEATTATAPAAEEGGIHK MGYG000001378_04234 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336309 0 0 0 0 0 0 0 415256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288006 0 0 0 0 510594 0 0 331525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255533 0 0 0 0 471346 0 0 415719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 590905 0 0 0 0 303532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDAPAAEQTEQQAVAPAAEATTAAAPAAEEGGIHK MGYG000000029_00498 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides finegoldii|m__MGYG000000029 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262677 0 0 290606 0 0 0 0 0 0 0 388771 0 358824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304234 0 0 0 0 432551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 844813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1409208 0 0 0 0 1502833 0 0 748663 0 566555 838347 0 0 0 0 0 0 0 297112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDAPAAEQTEQQAVAPAAEATTAAAPAAEEGGIHKEIK MGYG000000029_00498 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides finegoldii|m__MGYG000000029 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDAPKEEGFVFTTVK MGYG000000224_01762 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp003545565|m__MGYG000000224 1.0 COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia,4AKZY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase C1-like family 1.0 pepC 1.0 - 1.0 3.4.22.40 1.0 ko:K01372 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_C1,Peptidase_C1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 bleomycin hydrolase. aminopeptidase C (Lactococcus lactis). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain.-!-Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity.-!-Known from bacteria as well as eukaryotic organisms.-!-Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates.-!-Belongs to peptidase family C1. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1338056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDAQKEEPKEEGFVFTTVK MGYG000002478_02236;MGYG000004797_02345 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia,4AKZY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase C1-like family 1.0 pepC 1.0 - 1.0 3.4.22.40 1.0 ko:K01372 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_C1,Peptidase_C1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 bleomycin hydrolase. aminopeptidase C (Lactococcus lactis). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain.-!-Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity.-!-Known from bacteria as well as eukaryotic organisms.-!-Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates.-!-Belongs to peptidase family C1. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. 1.0 1.0 1.0 1.0 1.0 none 1.0 1983439 2022962 2461290 3182027 3707463 2912808 3462525 1588763 3416815 3007397 2786535 2228726 3624584 2700639 2018687 4385041 3745925 1804582 3208330 2723385 2662446 2303332 3218160 3004700 2333186 3035030 2829046 2408189 1832892 3083518 3319591 3276321 2478047 0 2472308 3008141 2256046 2061434 1497677 1374752 1580745 2055598 2351969 1858367 1715119 2364597 2109223 1328107 2145402 1784906 1936618 2075589 1329605 2218014 1318429 1142526 1960205 1765247 1781865 1702595 1304197 927043 1302082 1987963 1982276 1442689 1989796 1483692 876079 2401340 1771540 0 1774092 1765303 1731243 1234371 1023414 937751 1478773 1080560 2307302 1770110 1706462 880325 1916722 1632707 1747328 1797925 1956680 1473079 1324672 1331259 929052 2294797 1458503 1359432 963639 903669 1881520 1494009 911851 1270799 1150895 1845441 969527 1144654 2320177 884243 1281304 0 1217103 1750157 1514704 1079728 374973 333381 363790 448084 461193 556865 278548 424276 376103 679276 184028 454346 255354 461942 347348 329873 324090 0 634052 337339 306630 142493 0 310217 492439 530208 370518 0 488251 0 0 410098 655422 0 517735 865391 413346 391014 2683296 1395838 1884416 2196951 4160251 3250955 2903893 2477512 2976160 429906 1848349 2067790 3707725 1319456 1710311 3066563 2329351 5702387 2551118 3489112 876529 994065 5021274 2168700 3354854 2766866 2578924 4105061 2920914 3147493 2304073 1004969 1143836 0 2978976 2400149 2797774 2106849 -(Gln->pyro-Glu)QDASNC(Carbamidomethyl)NSNSSISHEAVR MGYG000003351_04948;MGYG000000196_00570;MGYG000000054_01567;MGYG000001378_02415 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1855752 1568930 1243968 1830679 0 1491729 2460206 1874697 1855143 1700084 3197967 1664589 0 0 1361642 1805533 2172316 0 0 1496162 1626564 1177575 0 1676358 1443391 1475162 0 0 1984200 0 0 1818244 1362594 1812650 1341198 1863958 1751004 1052268 472466 0 191721 506097 0 321312 394601 281688 196483 389447 318075 240250 0 0 169532 275819 326656 0 0 164123 427321 371179 0 386844 391762 368319 0 0 348909 0 0 477247 202782 420098 298987 228418 266243 193858 539004 760858 1246125 682211 0 405658 979817 563476 1053763 581608 858473 656095 0 0 697515 422694 778542 0 0 574513 566225 560410 0 698044 570333 749371 0 0 788932 0 0 485374 738391 639700 738059 983288 832081 1083080 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDATEQVVEGGMYQALK MGYG000001489_00789 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides goldsteinii|m__MGYG000001489 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,22WD0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 367193 0 537012 343022 553170 0 0 0 0 0 0 0 0 343415 0 0 385283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334520 0 277942 0 402058 0 0 289672 0 387514 0 0 0 0 0 0 272651 0 0 0 0 0 0 248266 603589 0 0 0 0 0 0 354006 0 0 0 0 0 0 0 0 0 0 0 0 366469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333133 255367 0 0 0 0 0 0 0 0 772167 0 0 0 0 999238 841051 888524 897599 828478 0 707672 1010553 0 596866 567246 0 0 359706 708761 0 381118 0 730478 0 1068720 0 0 713059 577655 0 0 0 0 0 0 1030772 0 -(Gln->pyro-Glu)QDATNC(Carbamidomethyl)NSNSSISHEAVR MGYG000002549_00688;MGYG000001345_01173 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1282128 1620065 0 0 0 0 0 0 3256676 0 0 0 1495108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 848886 681949 640987 0 0 978366 664518 0 0 1246510 0 0 0 791158 0 0 0 0 0 0 533189 0 519674 0 0 0 0 0 0 0 0 155401 0 0 0 0 591191 0 354978 0 0 0 0 0 0 0 0 1553924 0 0 0 0 0 0 0 0 0 0 0 0 1908950 0 0 0 0 0 0 0 0 528537 0 0 0 0 1070982 -(Gln->pyro-Glu)QDDNSSAKEEGNR MGYG000003697_01989;MGYG000002293_00403 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1629@1|root,COG4771@2|Bacteria,4NIXB@976|Bacteroidetes,2FNC3@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 beta-fructofuranosidase activity 1.0 scrL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_32C,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1446390 0 0 662984 0 0 0 0 1599355 0 2048031 0 0 0 0 0 0 0 0 1733414 0 1183454 0 0 0 0 0 0 0 0 1052267 0 0 0 0 1235382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDEAPAQTEQTAVVEEGGGLHK MGYG000000243_02202 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 9115832 9993030 24064773 12940884 13692250 12571542 11384146 9379734 11963690 8499581 8979634 8093934 11178512 11067563 9389902 14055559 12339150 8443098 9169081 7984695 10568849 8493062 8791417 13556209 7384154 9220331 9411748 8876745 10525101 13976562 19930963 11651080 26293639 12421169 9468758 11697014 8336577 28964010 3142538 2054343 3695849 0 5189308 3046657 2532499 4374425 4207476 3967769 3714277 3146745 5771564 4199021 3941315 4322660 4083180 1664774 3211469 3771048 3700558 3507434 2389595 2790750 3602655 3720467 3835738 1705233 2643537 3634302 2207109 3466428 3744676 3012385 3253129 3228337 3680716 2687178 5041948 3455157 5527392 5166359 7260460 6023473 6523755 3693412 7763897 3717945 5926536 6539653 6872598 4554533 4724404 5734399 4974113 7983471 4018707 4424810 4019785 3398677 7438939 5510375 0 5561116 4544512 5415291 5113236 3466639 6660068 3297220 3768098 1854713 5293555 6940064 5801149 6124094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262621 0 0 0 0 0 0 0 0 375445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211371 0 -(Gln->pyro-Glu)QDEAPAQTEQTAVVEEGGGLHKELK MGYG000000243_02202 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 5098834 9570526 48017642 8392602 22115987 9594505 5742094 11742497 8228518 6780386 9430260 7432146 10956993 9940167 5794440 10200109 10857165 4615966 9107758 6102388 5729219 7528492 3226809 9337723 6730844 7915109 5523813 3711298 6777828 7931631 25440766 14464409 38555001 7618507 7825239 4956342 6722531 37250899 499052 471708 576920 499065 1696384 583485 619706 592991 584285 949590 1105865 387224 1357439 478305 953713 947450 771634 0 336573 396453 430760 939972 0 656579 651042 520559 775816 0 892952 457496 393140 1135120 717141 648727 657299 552375 504252 723093 2571272 3466999 5005943 4453902 6286266 4495476 3420700 3278830 3814630 3352491 4806160 4203954 6495114 2534550 2273829 5129866 3445074 3931672 2781496 3066033 1958249 2231391 2579751 3574988 3171874 3616405 3070221 2222206 2691703 2153653 5149102 3041571 3156884 1502205 3230764 2930229 2983114 3020073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277394 0 0 0 353123 0 0 0 0 0 0 0 0 0 0 0 0 159050 0 0 0 150074 0 0 0 0 0 945796 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDELSHVFEK MGYG000000022_02144 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3WGES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270253 0 0 0 0 265399 0 0 0 0 131465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265245 0 0 0 0 401837 0 0 0 0 302041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 487974 0 0 0 0 0 0 0 0 0 370286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 595452 0 0 0 0 1076979 0 0 0 0 801401 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDFDNKPVVNVSNSK MGYG000003681_01830 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG3746@1|root,COG3746@2|Bacteria,4NK1Y@976|Bacteroidetes,2FKYR@200643|Bacteroidia,4AW00@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 ko:K07221 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.5.1 1.0 - 1.0 - 1.0 Porin_O_P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5697017 1962779 4451521 5257382 0 0 0 0 0 4887730 0 0 0 5887326 0 0 0 0 6583721 0 0 0 0 0 0 5535433 4785120 0 4862726 0 2722328 0 3888449 0 0 4807560 6572064 4382386 279929 399054 0 0 0 0 0 0 0 364279 0 0 0 380553 0 0 0 0 696763 0 0 0 0 0 0 440569 0 0 393762 0 419499 0 0 0 0 518908 674584 168169 1662543 1395175 1052846 2125013 0 0 0 0 0 1482883 0 0 0 1862144 0 0 0 0 2499060 0 0 0 0 0 0 2215326 2022878 0 2114657 0 1057190 0 1205508 0 0 2421767 1989108 1037135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDFDNNPVVNVSNSK MGYG000001313_00702 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG3746@1|root,COG3746@2|Bacteria,4NK1Y@976|Bacteroidetes,2FKYR@200643|Bacteroidia,4AW00@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 ko:K07221 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.5.1 1.0 - 1.0 - 1.0 Porin_O_P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 944253 0 0 0 0 0 1526466 0 1134292 1176706 0 0 0 0 946831 0 1520320 0 0 0 0 0 0 0 0 601772 816118 0 1001518 0 1241939 0 0 0 0 1316085 1017398 0 599695 0 0 0 0 0 755796 0 234859 411176 0 0 0 0 467521 0 698055 0 0 0 0 0 0 0 0 880736 395374 0 896921 0 269696 0 0 0 0 845390 751854 0 0 0 0 0 0 0 459552 0 0 457263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610241 0 0 0 0 0 0 0 0 0 332195 0 -(Gln->pyro-Glu)QDGEPHSHLAAMAK MGYG000001714_01569 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus_A|s__Coprococcus_A catus|m__MGYG000001714 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,36DR1@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.1.108,1.3.8.1 1.0 ko:K00248,ko:K22430 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. | short-chain acyl-CoA dehydrogenase. electron-bifurcating caffeoyl-CoA reductase. | unsaturated acyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. | One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. | a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 164204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 886027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDGPTALILSR MGYG000000107_04662;MGYG000000107_02891;MGYG000002494_04260;MGYG000002506_02537;MGYG000002323_03405 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,3XMMK@561|Escherichia 0.8 1236|Gammaproteobacteria 1.0 G 0.8 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate 1.0 tktA 1.0 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,ic_1306.c2990 0.8 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582533 0 336364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93143 0 254333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 123083 0 259942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDHN(Deamidated)GFSHQDPGVTSVLLNK MGYG000000756_01025;MGYG000002459_00966;MGYG000003452_01631;MGYG000003683_00701;MGYG000002395_00808;MGYG000001292_01832;MGYG000002469_00856;MGYG000001490_00761 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 565617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3136679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 229807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDHNGFSHQDPGVTSVLLNK MGYG000000756_01025;MGYG000002459_00966;MGYG000003452_01631;MGYG000003683_00701;MGYG000002395_00808;MGYG000001292_01832;MGYG000002469_00856;MGYG000001490_00761 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 1502209 0 0 0 821607 0 0 0 0 0 0 0 0 0 0 0 391055 0 0 0 827673 351471 2416371 0 0 0 390061 0 0 2452389 0 0 0 0 0 0 0 0 1184329 0 0 0 1323841 0 0 0 0 0 0 0 0 0 0 0 3204633 0 0 0 0 1138109 2492954 0 0 0 2109473 0 0 2157567 0 0 0 0 0 0 0 0 870102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 953017 0 0 0 896485 248283 356284 0 0 0 537367 0 0 601236 0 0 0 0 0 0 0 0 473634 0 0 0 377470 0 0 0 0 0 0 0 0 0 0 0 347611 0 0 0 747489 0 876416 0 0 0 424484 0 0 463679 0 0 0 0 0 0 0 0 0 0 0 0 604536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDIHVEIC(Carbamidomethyl)SK MGYG000002312_02603;MGYG000000213_02733;MGYG000000184_01331;MGYG000000201_01344;MGYG000000002_00125;MGYG000000200_00582;MGYG000004785_00522;MGYG000001338_01040 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZ78@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family 1.0 rumA 1.0 - 1.0 2.1.1.190 1.0 ko:K03215 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Methyltransf_31,TRAM,tRNA_U5-meth_tr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 23S rRNA (uracil(1939)-C(5))-methyltransferase. RNA uridine methyltransferase A. The enzyme specifically methylates uracil(1939) at C(5) in 23S rRNA.-!-The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues. S-adenosyl-L-methionine + uridine(1939) in 23S rRNA = 5-methyluridine(1939) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 839169 0 0 0 0 0 0 0 0 0 0 0 0 0 518503 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1209097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1276541 0 0 0 0 0 0 0 0 0 0 0 0 0 893209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1201005 0 0 0 0 0 0 0 0 0 0 0 0 0 618440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1469338 0 0 0 0 0 0 0 0 0 0 0 0 0 471838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDKGDWAIMPR MGYG000001415_02124 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG3637@1|root,COG3637@2|Bacteria,4NXWX@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 M 1.0 Outer membrane protein beta-barrel domain 1.0 - 1.0 - 1.0 - 1.0 ko:K11934 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6.2.1 1.0 - 1.0 - 1.0 OMP_b-brl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1074975 1078805 0 844170 955419 903245 1144324 1491707 1166024 0 0 0 0 1047525 0 798741 1091070 0 0 795121 858153 730786 0 1281894 0 902268 0 0 0 0 1446437 1188840 0 1357195 0 1014053 858830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502469 0 431258 0 339687 0 0 503609 0 0 0 0 0 0 0 715434 0 0 0 0 147023 0 0 0 498926 0 0 0 0 462344 305879 0 254789 0 416012 501026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDKYAAEYAAK MGYG000000174_02977;MGYG000000105_02297;MGYG000002438_00594;MGYG000001780_04721;MGYG000001661_00375;MGYG000000224_01350;MGYG000001346_00809;MGYG000003681_00189;MGYG000001313_03103;MGYG000001370_00206;MGYG000002455_01654;MGYG000001489_05046 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,2FSHK@200643|Bacteroidia,4AQYI@815|Bacteroidaceae 0.75 976|Bacteroidetes 0.75 J 0.75 Binds together with S18 to 16S ribosomal RNA 0.75 rpsF 0.75 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 0.75 - 1.0 ko:K02990 0.75 ko03010,map03010 0.75 M00178 0.75 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 0.75 - 1.0 - 1.0 - 1.0 Ribosomal_S6 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.75 none 1.0 335951 0 0 0 0 0 0 243454 0 0 356449 0 0 0 0 386300 0 0 0 0 259382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305815 0 270798 0 0 0 0 0 0 0 0 0 429412 0 0 0 0 315049 0 0 0 0 0 0 0 0 0 0 0 0 0 217176 0 447761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 145320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167849 0 0 0 0 0 0 0 0 0 0 428318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490986 0 0 0 895052 0 0 616971 602016 0 1248858 1003858 0 0 0 882813 0 0 0 0 1002112 0 0 0 0 701242 0 0 0 1321330 0 677261 0 649386 0 0 815633 0 -(Gln->pyro-Glu)QDLWFATK MGYG000000077_02534;MGYG000002992_01289;MGYG000004414_00496;MGYG000000076_00302;MGYG000000271_00043;MGYG000000650_00637;MGYG000004630_02109;MGYG000000378_02257;MGYG000002603_00810;MGYG000000146_00318;MGYG000002552_01282;MGYG000001637_01976;MGYG000000150_03719;MGYG000000489_00412;MGYG000002835_00491;MGYG000001687_00022;MGYG000004039_02130;MGYG000001528_02376;MGYG000002528_00841;MGYG000001311_03616;MGYG000000175_02007;MGYG000000099_02256;MGYG000000204_01085;MGYG000001314_02815;MGYG000000078_01372;MGYG000000154_00554;MGYG000000198_01314;MGYG000002133_00978;MGYG000002960_02247;MGYG000001645_01946;MGYG000003694_00268;MGYG000001374_01887;MGYG000002279_00786;MGYG000002523_00256;MGYG000001496_01079;MGYG000000135_00406;MGYG000003662_02146;MGYG000003147_02571;MGYG000000249_01884;MGYG000000139_01304;MGYG000000377_01969;MGYG000000562_01477;MGYG000002141_00952;MGYG000004271_00368;MGYG000002772_01345;MGYG000002517_01548;MGYG000000140_00828;MGYG000003695_00688;MGYG000003697_02877;MGYG000003427_02044;MGYG000004815_00205;MGYG000001770_01416;MGYG000000127_01878;MGYG000000312_00385;MGYG000004762_01414;MGYG000000038_01087;MGYG000000159_00506;MGYG000002080_02132;MGYG000000208_01206;MGYG000000080_02529;MGYG000004734_00467;MGYG000001056_02362;MGYG000000136_01284;MGYG000001714_01059;MGYG000001683_02046;MGYG000000179_01240;MGYG000001502_00893;MGYG000000272_02593;MGYG000002293_00899;MGYG000001781_00069;MGYG000001027_02002;MGYG000001607_00136;MGYG000002492_01799;MGYG000000268_00081;MGYG000002234_00368 domain d__Bacteria 1.0 COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia 0.21333333333333335 186801|Clostridia 0.8666666666666667 C 1.0 Belongs to the isocitrate and isopropylmalate dehydrogenases family 0.6533333333333333 icd 1.0 - 1.0 1.1.1.42 1.0 ko:K00031 1.0 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 1.0 M00009,M00010,M00173,M00740 1.0 R00267,R00268,R01899 1.0 RC00001,RC00084,RC00114,RC00626,RC02801 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Iso_dh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 isocitrate dehydrogenase (NADP(+)). oxalosuccinate carboxylase. Unlike EC 1.1.1.41, oxalosuccinate can be used as a substrate.-!-In eukaryotes, isocitrate dehydrogenase exists in two forms: an NAD(+)-linked enzyme found only in mitochondria and displaying allosteric properties, and a non-allosteric, NADP(+)-linked enzyme that is found in both mitochondria and cytoplasm.-!-The enzyme from some species can also use NAD(+) but much more slowly. D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;2-Oxocarboxylic acid metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Peroxisome;Glutathione metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 46280 0 0 36222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 52805 0 0 0 0 0 0 0 170395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64326 0 0 0 0 154454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56479 -(Gln->pyro-Glu)QDNELFHLR MGYG000002478_04584;MGYG000004797_02790 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4409@1|root,COG4409@2|Bacteria,4NFNK@976|Bacteroidetes,2FNCR@200643|Bacteroidia,4AMGI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 BNR Asp-box repeat protein 1.0 nanH 1.0 - 1.0 3.2.1.18 1.0 ko:K01186 1.0 ko00511,ko00600,ko04142,map00511,map00600,map04142 1.0 - 1.0 R04018 1.0 RC00028,RC00077 1.0 ko00000,ko00001,ko01000,ko02042 1.0 - 1.0 GH33 1.0 - 1.0 BNR,BNR_2,BNR_3,BNR_assoc_N 1.0 3.2.1.18 1.0 GH33 1.0 GH33 1.0 GH33 1.0 exo-alpha-sialidase. sialidase. The enzyme does not act on 4-O-acetylated sialic acids.-!-An endo-alpha-sialidase activity is listed as EC 3.2.1.129.-!-See also EC 4.2.2.15. Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. 1.0 1.0 1.0 1.0 Other glycan degradation;Sphingolipid metabolism;Lysosome 1.0 none 1.0 0 0 0 0 0 0 0 258669 170954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248143 289746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 504749 438087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDPMALQR MGYG000000196_01218;MGYG000003266_00564;MGYG000000357_00601;MGYG000000003_01212;MGYG000001562_02334;MGYG000002905_01326;MGYG000000074_02347;MGYG000003423_00341;MGYG000000098_00251;MGYG000003279_01430;MGYG000002218_02599;MGYG000001420_01443;MGYG000000053_01169;MGYG000001567_00204 domain d__Bacteria 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,22UA3@171550|Rikenellaceae 0.42857142857142855 976|Bacteroidetes 0.8571428571428571 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 597301 0 0 0 0 0 0 0 607205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 96306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564660 0 0 0 0 0 0 0 314515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670308 0 0 0 0 0 0 0 439476 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110937 0 0 0 0 0 0 0 200752 0 0 0 -(Gln->pyro-Glu)QDPSFGHPEK MGYG000000249_02121;MGYG000000216_00347;MGYG000000022_01381;MGYG000004733_00873;MGYG000000251_00145;MGYG000001338_00189;MGYG000001292_00841;MGYG000002469_01404;MGYG000002517_00467;MGYG000000133_01077;MGYG000000271_02405;MGYG000001300_00435 domain d__Bacteria 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia 0.4166666666666667 186801|Clostridia 0.8333333333333334 S 1.0 MCRA family 0.5833333333333334 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 1.0 none 1.0 394132 0 0 246757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257422 0 0 0 0 500188 1475847 342373 573984 0 332095 0 0 427789 0 0 0 0 0 0 0 0 0 0 149838 0 0 0 640015 0 325898 0 0 0 0 0 500744 301638 479781 0 0 153115 355394 0 533053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275832 0 0 0 0 0 0 0 0 0 344957 0 0 0 0 0 0 0 408424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 594110 905217 866072 0 0 447559 0 0 483547 0 0 0 0 0 0 0 0 0 0 521862 0 764952 0 668880 0 876172 0 0 0 0 0 763957 843679 830767 0 0 468611 688879 -(Gln->pyro-Glu)QDPSFGHPEKFC(Carbamidomethyl)SDIAK MGYG000000216_00347;MGYG000000251_00145;MGYG000001338_00189 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 S 1.0 Myosin-crossreactive antigen 0.6666666666666666 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456659 0 0 0 0 236236 -(Gln->pyro-Glu)QDQKPPEPPK MGYG000000074_00226 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,2FPKW@200643|Bacteroidia,22UEA@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins 1.0 - 1.0 - 1.0 - 1.0 ko:K03832 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 2.C.1.1 1.0 - 1.0 - 1.0 TonB_C,VIT,VWA_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 243392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 538840 0 0 0 0 0 0 0 0 0 0 0 337510 0 0 0 0 0 0 0 197969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458638 0 0 0 0 0 0 0 0 0 0 0 939955 0 0 0 0 0 0 0 540234 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDTNYYTPK MGYG000002478_04508 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG2885@1|root,COG2885@2|Bacteria,4P1BJ@976|Bacteroidetes,2FPC4@200643|Bacteroidia,4AMH8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 - 1.0 OMP_b-brl,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 534518 0 0 0 0 0 0 0 0 0 0 0 0 0 376025 0 437887 260775 864708 0 0 0 318583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1276342 0 0 0 0 0 0 0 0 0 0 0 884291 0 1276949 0 1190198 1242401 1338986 0 0 0 916867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 817659 0 0 0 0 0 0 0 0 0 0 0 1383445 0 559223 0 646038 1167123 767840 0 0 0 914624 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271338 0 0 0 0 0 0 0 0 0 0 0 624119 0 357434 0 588292 771265 352005 0 0 0 429375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 811284 0 0 0 0 0 0 0 0 0 0 0 1872234 0 1278121 0 442241 1524987 558954 0 0 0 1471599 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDVEFKR MGYG000002960_00143;MGYG000003697_02150 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0246@1|root,COG0246@2|Bacteria,4NEMT@976|Bacteroidetes,2FP8Z@200643|Bacteroidia,4ATAV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Mannitol dehydrogenase Rossmann domain 1.0 uxuB 1.0 - 1.0 1.1.1.17,1.1.1.58,1.1.1.67 1.0 ko:K00009,ko:K00041,ko:K00045 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00631 1.0 R00868,R02555,R02703 1.0 RC00085 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Mannitol_dh,Mannitol_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 mannitol-1-phosphate 5-dehydrogenase. | tagaturonate reductase. | mannitol 2-dehydrogenase. Tagaturonate dehydrogenase. | mannitol dehydrogenase. - D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + H(+) + NADH. | D-altronate + NAD(+) = H(+) + keto-D-tagaturonate + NADH. | D-mannitol + NAD(+) = D-fructose + H(+) + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2724850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3182522 0 3246192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469653 0 339327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDVIDKFK MGYG000000233_01543;MGYG000000255_00343 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,21YPK@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431494 463857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378444 166349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194034 140414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDVPSFRPGDTVEVK MGYG000002323_03125;MGYG000002477_01825;MGYG000003365.1_02196;MGYG000002494_04624;MGYG000001465_01866;MGYG000002500_03584;MGYG000000337_01318;MGYG000003360_03259;MGYG000003390_02497;MGYG000002535_00930;MGYG000002504_03064;MGYG000003883_03143;MGYG000002506_02124;MGYG000002515_00446;MGYG000002502_01722;MGYG000003372_01568;MGYG000000093_05408 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1Y8KB@135625|Pasteurellales 0.8823529411764706 135625|Pasteurellales 0.8823529411764706 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 0.8823529411764706 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1158461 0 366165 933984 0 974124 1258024 902782 1123496 984006 630853 1057405 0 841070 946442 343926 632000 0 520110 0 861395 1288310 0 779347 832550 661635 847738 0 863313 883557 0 519088 0 1074928 735164 973620 695619 739541 1911793 1518556 2071290 1855405 0 3929104 2059531 2017295 1989452 2942269 1055042 1876600 0 2314189 1995275 1525052 2401458 0 2675518 0 2313088 4432919 0 2969127 2807951 1926294 1956409 0 2702544 2607957 1168977 1683704 2360248 1746063 1812655 1616189 1586872 1917680 700984 515555 1047221 738607 0 1856102 0 870534 935542 1119447 556271 755939 0 877776 897503 865101 734774 0 1059774 0 1096728 1077700 0 1478178 1141828 799628 1019388 0 781588 984178 664494 0 830906 0 973509 1225901 917451 0 1113538 549990 461949 791996 0 871747 1065099 1301438 487155 1172893 526624 615225 0 1017437 953740 556542 625932 0 619325 0 1307441 884149 0 547412 1218392 1181422 1045847 0 686259 612321 0 1079499 303684 1835808 1775722 1278985 916341 549532 0 0 0 0 0 0 0 0 0 0 0 355309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDVTGTIHANQGTQK MGYG000002293_00077 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,2FNNB@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Alpha-L-arabinofuranosidase domain protein 1.0 abf2 1.0 - 1.0 3.2.1.55 1.0 ko:K01209 1.0 ko00520,map00520 1.0 - 1.0 R01762 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH51 1.0 - 1.0 Alpha-L-AF_C 1.0 3.2.1.55 1.0 GH51 1.0 GH51 1.0 GH51 1.0 non-reducing end alpha-L-arabinofuranosidase. arabinosidase. Acts on alpha-L-arabinofuranosides, alpha-L-arabinans containing (1,3)- and/or (1,5)-linkages, arabinoxylans and arabinogalactans.-!-Some EC 3.2.1.23 and EC 3.2.1.38 enzymes also hydrolyze alpha-L- arabinosides. cf. EC 3.2.1.185.-!-Formerly EC 3.2.1.79. Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18610611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1459641 0 0 0 0 2125057 0 0 0 0 606164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDVTGTIHASQGTQK MGYG000003697_02024 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,2FNNB@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Alpha-L-arabinofuranosidase domain protein 1.0 abf2 1.0 - 1.0 3.2.1.55 1.0 ko:K01209 1.0 ko00520,map00520 1.0 - 1.0 R01762 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH51 1.0 - 1.0 Alpha-L-AF_C 1.0 3.2.1.55 1.0 GH51 1.0 GH51 1.0 GH51 1.0 non-reducing end alpha-L-arabinofuranosidase. arabinosidase. Acts on alpha-L-arabinofuranosides, alpha-L-arabinans containing (1,3)- and/or (1,5)-linkages, arabinoxylans and arabinogalactans.-!-Some EC 3.2.1.23 and EC 3.2.1.38 enzymes also hydrolyze alpha-L- arabinosides. cf. EC 3.2.1.185.-!-Formerly EC 3.2.1.79. Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1147459 0 0 0 0 1549245 0 0 0 0 893947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QDVVTFNEKPVQIESK MGYG000002438_00809 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,2FP7M@200643|Bacteroidia,22WKX@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the pseudouridine synthase RsuA family 1.0 rluB 1.0 - 1.0 5.4.99.22 1.0 ko:K06178 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03009 1.0 - 1.0 - 1.0 - 1.0 PseudoU_synth_2,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 23S rRNA pseudouridine(2605) synthase. - Pseudouridine synthase RluB converts uridine(2605) of 23S rRNA to pseudouridine. uridine(2605) in 23S rRNA = pseudouridine(2605) in 23S rRNA. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553062 0 0 0 0 0 0 0 0 519705 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEAEAFYAVHR MGYG000003352_00067;MGYG000003022_00269 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,1KKKW@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 F 1.0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate 1.0 ndk 1.0 - 1.0 2.7.4.6 1.0 ko:K00940 1.0 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 1.0 M00049,M00050,M00052,M00053 1.0 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000,ko04131 1.0 - 1.0 - 1.0 - 1.0 NDK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 nucleoside-diphosphate kinase. nucleoside diphosphokinase. Many nucleoside diphosphates can act as acceptors.-!-Many ribo- and deoxyribonucleoside triphosphates can act as donors. (1) a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP. (2) a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism;MAPK signaling pathway - plant;Purine metabolism;Biosynthesis of secondary metabolites;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 246913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 455188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEAIYKK MGYG000001306_03308 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141430 0 0 0 0 2794921 0 0 0 0 2185913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239078 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEAKEEPKEEGFVFTTVK MGYG000000243_01742 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia,4AKZY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase C1-like family 1.0 pepC 1.0 - 1.0 3.4.22.40 1.0 ko:K01372 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_C1,Peptidase_C1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 bleomycin hydrolase. aminopeptidase C (Lactococcus lactis). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain.-!-Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity.-!-Known from bacteria as well as eukaryotic organisms.-!-Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates.-!-Belongs to peptidase family C1. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. 1.0 1.0 1.0 1.0 1.0 none 1.0 1776283 2147313 6017045 2400219 3616299 1775163 2561368 0 2172317 1649974 1833656 0 2194470 2172003 1716974 2111515 2235731 0 2015705 1535138 0 1876803 0 2529020 1804751 2161879 2114495 0 0 0 5363084 2756420 7211398 2638205 0 2263176 1938898 6720679 417512 281141 447902 513714 800908 490901 357489 0 535475 548297 452092 0 438440 445875 712940 728943 627609 0 276057 462535 0 526734 0 359626 548809 660807 691321 0 0 0 304956 658086 582233 529992 0 448132 485432 336416 1053692 833492 1045800 970750 1375434 1112475 1016345 0 1165199 868345 944926 0 1606848 1022854 889579 1315649 722111 0 979024 279625 0 714983 0 360263 896809 423588 998990 0 0 0 1148068 727503 497729 348233 0 409266 1071899 917042 231507 0 0 0 0 0 0 0 336688 0 0 0 0 411637 306572 0 0 0 0 0 0 531857 0 0 833854 0 0 0 0 0 0 0 278328 0 0 0 512207 0 0 0 0 119938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188627 0 232575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEAKPAAAPK MGYG000000003_00808 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 2EGII@1|root,33AAP@2|Bacteria,4NXMZ@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4890,LTXXQ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 3138586 0 0 0 0 0 0 0 0 0 0 2132353 0 0 0 4523155 0 4233297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212575 0 0 0 0 0 0 0 0 0 0 121329 0 0 0 142696 0 253734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721253 0 142978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 694866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEAPIHISNLNPVDPK MGYG000001364_02743;MGYG000000042_01080;MGYG000001306_02671;MGYG000001789_00119;MGYG000001925_01443 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,2FT5V@200643|Bacteroidia,22Y4Z@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit 1.0 rplX 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02895 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KOW,ribosomal_L24 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656422 0 0 0 0 996174 0 0 0 0 867010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEATETAVEGGMYQALK MGYG000002033_00945;MGYG000000138_04126 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,22WD0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 978315 1217414 1211313 1316488 1209337 931933 1877463 1517141 1628050 0 1188192 1604345 904357 1263758 444841 0 0 461866 1387475 997560 1434549 861942 1321062 1314436 1141922 1554754 1247705 1494787 0 0 0 1878012 1292311 1406862 1634405 1464265 1242974 1011912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449622 0 0 0 0 435609 0 0 0 0 0 0 0 0 0 0 1052549 757751 1095554 1145663 1619471 1285256 1067144 1037540 1144491 0 1047992 1447399 1043181 973533 975283 0 0 930172 1005386 922903 542919 340767 1058797 1031499 928719 784750 935815 794764 0 0 0 917237 698051 774955 1145976 1096883 865159 856885 1540227 1496860 1493220 1290622 1334261 1488957 1313196 1428267 1551720 0 1206153 1540952 1140705 1302405 1410459 0 0 872545 1390447 1177253 645480 1174389 1223845 1408233 1394806 1385532 1531649 813700 0 0 0 2331639 1494079 2147313 1771474 1838516 1820390 1458541 656274 528926 630512 662394 344504 586914 769280 690727 628623 0 500639 437885 960404 471374 412286 0 0 0 426347 572930 210441 468855 1831832 309335 674632 647503 618369 0 0 0 0 711043 525404 951138 635488 552996 500939 516905 -(Gln->pyro-Glu)QEDIKVK MGYG000000074_02170 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia,22UGQ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Biopolymer transport protein ExbD/TolR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ExbD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111170 0 0 0 0 0 0 1250839 0 0 0 391264 0 0 0 0 0 0 1087493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343693 0 0 0 0 0 0 0 0 334876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 536202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1536315 1316832 0 0 0 0 0 1285673 0 0 0 1221853 0 0 0 0 0 0 1202231 0 -(Gln->pyro-Glu)QEDNQVVVTRPNDLKK MGYG000002528_01854 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center 1.0 rplF 1.0 - 1.0 - 1.0 ko:K02933 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEFKPQVGFSNEAGYK MGYG000000138_03404;MGYG000000044_03456 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG2885@1|root,COG2885@2|Bacteria,4NKQC@976|Bacteroidetes,2FRBK@200643|Bacteroidia,22X13@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 - 1.0 GO:0001871,GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0006810,GO:0008150,GO:0015267,GO:0015288,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030246,GO:0030247,GO:0051179,GO:0051234,GO:0055085 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 1597604 0 0 0 0 0 0 0 0 0 0 0 0 772258 0 0 0 0 0 0 1153668 0 0 0 1272224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 229675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1390365 0 0 0 0 0 0 0 0 0 0 0 0 705576 0 0 0 0 0 0 1214900 0 0 0 1030692 0 0 0 0 0 0 0 0 0 0 0 0 0 998441 0 0 0 0 0 0 0 0 0 0 0 0 1277495 0 0 0 0 0 0 1284049 0 0 0 1234376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541220 0 0 0 0 0 0 379952 0 0 0 281868 0 0 -(Gln->pyro-Glu)QEGTLGKPVASDYQR MGYG000002438_00500 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,2324H@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 973680 0 0 0 0 766511 0 0 0 0 810920 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEHDAIC(Carbamidomethyl)DWVFDKDPDFK MGYG000000022_02380 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,3WQA7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Aldehyde ferredoxin oxidoreductase, N-terminal domain 1.0 - 1.0 - 1.0 1.2.7.5 1.0 ko:K03738,ko:K19515 1.0 ko00030,ko00362,ko01100,ko01120,ko01200,map00030,map00362,map01100,map01120,map01200 1.0 M00309,M00541 1.0 R08571,R10961 1.0 RC00242,RC01839 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AFOR_C,AFOR_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aldehyde ferredoxin oxidoreductase. tungsten-containing aldehyde ferredoxin oxidoreductase. This is an oxygen-sensitive enzyme.-!-Catalyzes the oxidation of aldehydes (including crotonaldehyde, acetaldehyde, formaldehyde and glyceraldehyde) to their corresponding acids.-!-However, it does not oxidize glyceraldehyde 3-phosphate (see EC 1.2.7.6).-!-Can use ferredoxin or methylviologen but not NAD(P)(+) as electron acceptor. an aldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = a carboxylate + 3 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Benzoate degradation;Metabolic pathways;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 514695 0 0 0 0 182143 0 0 0 0 657578 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302109 0 0 0 0 341783 0 0 0 0 275363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2244370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QELDLLK MGYG000002478_02020 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,4AKEY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QENPNKPDNIIEK MGYG000002279_01754;MGYG000000038_00954 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,27V7M@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 965657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 758816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QENQLTAIR MGYG000001315_01374;MGYG000000038_01351;MGYG000001338_03290;MGYG000004733_00268;MGYG000002298_02804;MGYG000000171_02327;MGYG000000212_02591;MGYG000000200_02310;MGYG000000184_01074;MGYG000000213_01826;MGYG000000133_00794 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3Y1DY@572511|Blautia 0.9090909090909091 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 0.9090909090909091 - 1.0 - 1.0 - 1.0 ko:K02058 1.0 - 1.0 M00221 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1.2 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 384093 0 0 0 0 0 0 0 0 0 742469 0 0 0 0 428098 0 0 0 0 474351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 649440 0 0 0 0 412621 0 0 0 0 713688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159227 0 0 0 0 0 0 0 0 0 171875 0 0 0 0 315597 0 0 0 0 149655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436419 0 0 0 0 0 0 0 0 0 343087 0 0 0 0 806014 0 0 0 0 1208246 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEPGIK MGYG000000212_02158 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3XZRM@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 8.87 1.0 glgD 1.0 - 1.0 2.7.7.27 1.0 ko:K00975 1.0 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 1.0 M00565 1.0 R00948 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Hexapep,NTP_transferase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-1-phosphate adenylyltransferase. ADP-glucose synthase. - alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Biofilm formation - Escherichia coli;Metabolic pathways;Starch and sucrose metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 70335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QESNAAIR MGYG000000196_00914 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 2924H@1|root,2ZPPH@2|Bacteria,4NNST@976|Bacteroidetes,2FR7C@200643|Bacteroidia,4AMVX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG27363 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4251 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 874537 0 0 0 0 864902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEVELTKEEK MGYG000001364_00890;MGYG000003693_02102 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2924H@1|root,2ZPPH@2|Bacteria,4NNST@976|Bacteroidetes,2FR7C@200643|Bacteroidia,4AMVX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG27363 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4251 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1865167 0 0 0 0 3026084 0 0 0 0 1761124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 655887 0 0 0 0 0 0 0 0 0 944669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEVELTKEEKK MGYG000003693_02102 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 2924H@1|root,2ZPPH@2|Bacteria,4NNST@976|Bacteroidetes,2FR7C@200643|Bacteroidia,4AMVX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG27363 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4251 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 891020 0 0 0 0 986755 0 0 0 0 818058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEVKEEGK MGYG000000243_02431;MGYG000002171_00876 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2885@1|root,COG2885@2|Bacteria,4NKM0@976|Bacteroidetes,2FP8P@200643|Bacteroidia,4AN93@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 COG2885 Outer membrane protein and related peptidoglycan-associated 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HALZ,OMP_b-brl,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1399690 1465892 6976061 3182870 2893948 1549714 2541851 0 2299709 0 2815735 2394106 3180031 1928870 2871586 2432787 2622152 2664470 2460133 0 0 2353440 2216732 3019106 2315874 2182056 1642296 1752815 2388723 2074799 6432049 0 6012654 2322967 0 2277554 2088405 7596490 608284 392016 585595 1080611 1547684 733597 1254227 0 381766 0 657136 377820 1397692 745223 679147 990663 413998 214363 433996 0 0 741659 465203 660248 635337 802365 843235 0 635520 824157 639328 0 819272 838207 0 717999 644191 580179 830804 1178770 1473414 1921173 1899065 1490808 985841 0 1497591 0 1473200 1354052 2498680 1035143 1284400 2103061 1017604 184069 1780885 0 0 1393528 975159 1287333 1363993 2031049 1186162 557590 1495327 1383046 1783720 0 1401502 811193 0 1798558 1540601 1893733 122518 165244 181960 0 0 88056 0 0 0 0 204716 324661 0 0 0 0 186173 243874 0 0 0 243378 140202 0 93184 0 0 6970 0 0 154051 0 0 0 0 0 243576 0 0 0 0 214836 0 0 0 0 0 0 0 83507 0 0 0 0 54406 0 0 0 0 108311 0 204189 0 0 189262 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEWADGGKEK MGYG000002517_00541;MGYG000000154_01283 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 593892 278109 0 641125 234566 264337 0 564322 335309 719186 0 308500 0 0 820498 330490 503831 0 714490 555354 835373 0 0 0 729609 470372 638808 0 190597 467043 0 0 0 429513 418676 441937 422385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170673 0 0 0 226854 0 0 250900 0 0 0 255774 0 410569 0 306466 0 277045 401993 189789 0 0 320188 407160 337988 0 0 0 281751 691118 296158 0 0 335910 293675 0 0 346766 501466 0 493374 342241 4362590 1186907 1255284 5199218 2988373 1615230 3111109 4763869 5663828 2802058 1749810 2512703 0 5892227 4562257 1835464 3846623 0 4404079 5599241 2665102 428727 0 431275 6572733 5076550 6275164 0 1765841 4993077 1405808 1913239 1192889 1477633 5010647 3812250 5477986 1180635 2930183 3019716 4182031 0 876330 2504700 3517961 2884090 2931403 4835203 2996426 3749645 0 5311570 5366512 3151988 4060561 0 3738774 1740495 4868815 2628934 0 2450949 6298530 5042886 4941878 0 923483 1991759 2473563 950560 4960061 4444558 4917581 7013188 4642589 3409114 -(Gln->pyro-Glu)QEWAEGGKDK MGYG000000018_00070;MGYG000003422_00257;MGYG000002492_00658;MGYG000001707_00051;MGYG000001319_02236 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 270719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454982 0 0 0 0 445469 0 0 0 0 452790 0 0 0 0 242322 0 0 0 0 0 0 0 476980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1399000 0 0 0 0 1979212 0 0 0 0 506283 0 0 0 0 726805 0 0 1141730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 730903 0 0 0 0 1211531 0 0 0 0 1308079 0 0 0 0 1049818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEWAEGGKEK MGYG000003486_02523;MGYG000000245_02020 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 484144 0 0 0 0 0 0 0 0 0 0 496502 479740 0 0 0 0 0 0 0 0 0 0 0 0 617350 0 0 0 593555 0 0 0 0 0 0 681195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEWAEN(Deamidated)GLAK MGYG000002619_02238;MGYG000001300_00294;MGYG000003899_01135;MGYG000000022_01323;MGYG000001255_01113;MGYG000002272_01496;MGYG000003166_01335;MGYG000002040_01716 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 243895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 713013 0 0 0 0 0 0 0 378835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 782521 0 0 0 0 0 0 0 844531 0 0 0 0 0 0 1307563 0 0 0 0 0 0 0 758071 0 0 0 985073 952630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416462 0 0 0 0 0 0 0 540489 0 0 0 0 0 0 614609 0 0 0 0 0 0 0 0 0 0 0 512208 214160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEWAENGLAK MGYG000002619_02238;MGYG000001300_00294;MGYG000003899_01135;MGYG000000022_01323;MGYG000001255_01113;MGYG000002272_01496;MGYG000003166_01335;MGYG000002040_01716 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 623117 646153 671378 789986 243901 498976 468440 0 518080 0 0 742837 0 527707 0 0 381748 554639 692987 657857 0 671625 728176 518130 711918 925449 737055 617752 0 0 514264 274749 671067 918175 0 756056 570968 755193 1145954 1709162 1403828 1357274 922798 1501722 1832431 0 1495977 0 0 1314990 0 1258514 0 0 1082410 869184 1817660 1739314 0 914208 1087550 1449152 1681328 963606 1380626 1688186 0 0 2058751 1115898 1195332 906546 0 828934 890177 1199221 346775 192692 296440 430731 0 258481 553367 0 327297 0 0 447499 0 416298 0 0 163901 806843 176048 301543 0 0 755412 335091 260161 532911 272600 802284 0 0 614074 156512 299963 376286 0 393154 453461 368436 509652 545609 664874 620825 775071 606121 900633 0 759639 0 0 937019 0 671843 0 0 482521 418063 678193 699785 0 0 0 424500 367465 692017 450646 0 0 0 828381 552041 796576 452488 0 571472 655461 756305 0 219908 0 0 0 0 0 0 0 0 0 132824 0 122660 0 0 0 858349 172983 0 0 0 914426 0 125083 0 0 141422 0 0 0 271090 300083 167291 0 158439 218723 279671 -(Gln->pyro-Glu)QEYNLSLQGGNAK MGYG000002478_01935 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489334 0 0 0 0 0 0 0 759794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 214643 0 0 0 0 0 0 0 292488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QEYQPQVGFSNEAGYK MGYG000002438_03857 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG2885@1|root,COG2885@2|Bacteria,4NKQC@976|Bacteroidetes,2FRBK@200643|Bacteroidia,22X13@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 - 1.0 GO:0001871,GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0006810,GO:0008150,GO:0015267,GO:0015288,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030246,GO:0030247,GO:0051179,GO:0051234,GO:0055085 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 356659 0 0 0 0 0 0 0 0 0 0 520120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304844 0 0 0 0 296901 529760 561802 543416 0 662085 502524 623713 812513 0 787174 0 2384239 0 600189 0 1000289 0 0 687091 380356 4013331 765956 372506 655411 0 844303 0 0 563522 2693687 629132 0 840328 574558 739243 775029 930190 684319 917806 0 0 0 596863 929718 527511 417264 0 504261 0 1750389 0 0 0 0 0 1185231 0 0 3117007 0 0 635094 0 406616 0 0 0 2384750 927784 0 0 0 705080 697619 676778 0 619617 519874 355566 0 492146 342231 359827 533181 0 453702 0 1319406 0 416950 0 501537 0 0 477668 490662 5296053 0 0 0 0 0 0 0 236358 1712868 311238 0 519154 474959 593348 509320 429946 0 1432314 1715216 1375152 0 2776472 1660239 1585848 1679423 0 1682876 0 4058438 0 1467220 0 2227566 0 2063736 1421117 1522203 4945252 625966 1900131 1560875 0 1696979 0 1371521 1573997 5886848 1711759 0 1210639 1437969 1764834 1580377 1665227 1265107 -(Gln->pyro-Glu)QFAETEVKPLAQETDETEVFPAETVAK MGYG000001186_01721;MGYG000002492_00659;MGYG000002670_01509 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 327268 0 336062 0 0 0 0 0 0 0 377696 0 0 270173 0 237915 0 0 0 0 0 0 250043 0 0 0 0 0 0 0 235510 0 0 0 0 0 0 0 681775 0 1197436 0 0 0 0 0 761010 0 611319 0 0 399920 0 2539888 0 422888 0 0 1824219 0 624528 0 0 2458353 0 0 560107 474141 733539 0 0 0 0 966960 0 0 3235710 0 1021608 0 0 0 0 0 1232811 0 1655488 0 0 1764799 0 779625 0 692184 0 0 1040243 0 801053 0 0 1779218 0 0 1332560 1045991 3528873 0 0 0 0 2628654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141937 0 422009 0 0 0 0 387876 0 0 0 0 377587 0 0 286294 0 0 0 0 0 0 213852 0 0 0 0 1498035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QFAFTLR MGYG000002494_02439 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,3X2BS@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 M 1.0 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell 1.0 mscL 1.0 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 1.0 - 1.0 ko:K03282 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.22.1 1.0 - 1.0 - 1.0 MscL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193832 164608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125893 0 0 0 0 106530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QFAKDNK MGYG000000251_02358;MGYG000001319_00507;MGYG000000002_00433 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QFDAVMEHINHANDLGTTK MGYG000002517_02762 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0840@1|root,COG0840@2|Bacteria,1TY0J@1239|Firmicutes,24DGH@186801|Clostridia 1.0 186801|Clostridia 1.0 NT 1.0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). 1.0 - 1.0 - 1.0 - 1.0 ko:K03406 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 MCPsignal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403276 0 0 0 0 0 0 0 0 0 0 638783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174821 0 -(Gln->pyro-Glu)QFDDRYMMLK MGYG000000255_01557 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36EI7@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 1387244 741107 1003064 0 0 0 0 0 0 0 0 0 762966 766042 0 0 0 0 0 518851 0 694490 0 0 0 0 0 958335 0 0 0 0 0 0 0 0 0 0 1440556 756967 1500854 0 0 0 0 0 0 0 0 0 1088172 798661 0 0 0 0 0 1322482 0 1367328 0 0 0 0 0 984791 0 0 0 0 0 0 0 0 0 0 664517 474823 636761 0 0 0 0 0 0 0 0 0 451328 391213 0 0 0 0 0 632900 0 472610 0 0 0 0 0 542904 0 0 0 0 0 0 0 0 0 0 920516 479127 435888 0 0 0 0 0 0 0 0 0 564177 573829 0 0 0 0 0 629954 0 650054 0 0 0 0 0 684728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QFDGMTFR MGYG000004479_01116;MGYG000002560_01730;MGYG000001789_02092;MGYG000000042_02678;MGYG000003693_00676;MGYG000001306_03824;MGYG000001337_03683;MGYG000002478_04117;MGYG000003221_00209;MGYG000001364_01848;MGYG000001835_01025;MGYG000000243_00095;MGYG000004763_00186 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 146516 0 501698 0 426224 236152 0 311224 95759 325578 229279 0 424768 237700 0 310343 0 181541 0 0 307428 275219 307795 408442 0 259080 226885 240786 0 0 316251 0 602543 0 204397 0 309329 476625 143005 0 224436 0 363027 255260 0 322890 213944 337052 286189 0 453743 227723 0 420924 0 503439 0 0 190697 209390 590106 190017 0 218777 235575 526071 0 0 72335 0 220889 0 270698 0 257541 169651 0 0 88161 0 189490 80122 0 0 69726 74134 102802 0 296549 67340 0 244559 0 229719 0 0 58627 64960 335165 98162 0 76032 140245 213393 0 0 94084 0 0 0 0 0 88307 65842 50000 0 75150 0 0 104125 0 66979 127738 90365 65807 0 156520 83128 0 0 0 100094 0 0 255724 0 0 72139 0 102781 199305 127554 0 0 91070 0 90761 0 265305 0 119323 0 276061 0 216941 0 708765 286663 0 302642 312695 184852 303891 0 308013 301124 0 452812 0 482811 0 0 159279 105502 455905 147302 0 94917 174435 578014 0 0 150773 0 137895 0 242163 0 0 305857 -(Gln->pyro-Glu)QFEDGYHIIK MGYG000004718_00706;MGYG000000177_01042;MGYG000000016_02517 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36EI7@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1807828 1674957 1817293 0 0 1730729 0 0 0 2509191 0 0 0 0 2240264 0 2250475 0 0 2010300 2021125 1962192 0 1296539 0 2104725 1790680 0 1803957 0 1009129 0 1591952 1991864 1816593 0 1390463 1360210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 785644 1120474 1008894 0 0 492991 0 0 0 938916 0 0 0 0 1237631 0 398153 0 0 1141082 687882 585801 0 655005 0 574812 1229294 0 1188024 0 616932 0 1055180 650764 1297163 0 545832 1065206 864643 385837 1397056 0 0 947960 0 0 0 1455214 0 0 0 0 808937 0 501299 0 0 730774 229835 1154962 0 2054197 0 918750 589375 0 1161619 0 1304019 0 1902120 1419653 940152 0 684051 1446733 401997 235580 337055 0 0 0 0 0 0 809661 0 0 0 0 746321 0 370123 0 0 304926 434792 0 0 186160 0 542390 393169 0 761757 0 755887 0 428811 563996 624764 0 455627 364970 -(Gln->pyro-Glu)QFEDRYHVLK MGYG000000164_00687;MGYG000000127_04021;MGYG000001315_01867;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1606093 1746402 1522857 459970 2413040 1827059 1570373 3017988 1987300 3098730 1706339 1428464 3778255 1854127 3105686 2578755 1904563 0 1738444 2550927 2536154 1818240 0 674621 3029670 1856672 1976931 0 1637009 1895525 612820 1274633 868630 1966398 2636533 1414081 1555640 894140 503382 807021 781649 557359 950876 612979 562726 661256 481570 565966 517373 263709 851554 349567 492084 507500 264920 0 532232 527934 415264 240734 0 741150 720043 532039 696188 0 846182 421645 921607 1071440 694231 689372 725743 516051 454111 1064307 451965 483873 288499 176926 165726 139892 251371 577542 247610 367198 163980 356901 435532 277414 417782 453445 220530 0 208227 426948 322663 342069 0 331706 485472 364031 457845 0 327838 411912 253893 366307 577431 85627 533253 226442 426834 292806 190769 331086 886655 202754 421920 92050 307179 253089 69890 238668 494275 655049 553459 225302 174515 523616 141284 0 277694 87796 235205 603843 0 432444 95772 173948 270450 0 85570 381655 395723 328409 850605 0 322094 87632 63669 1092240 239299 0 808594 387082 102661 363422 90255 189950 185661 162580 220728 317126 174148 306932 236133 166617 250308 0 182050 0 224107 127254 0 67359 246524 293476 256144 0 220753 0 242498 212536 929801 320386 104124 211025 366492 943981 -(Gln->pyro-Glu)QFFDEHQATYPTR MGYG000002506_02758 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1882@1|root,COG1882@2|Bacteria,1MWYE@1224|Proteobacteria,1RWKK@1236|Gammaproteobacteria,3XMIN@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 formate acetyltransferase 1.0 tdcE 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016020,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017144,GO:0019541,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0043875,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046459,GO:0070689,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcSMS35_1347.EcSMS35_3410 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311990 0 0 0 0 0 0 0 362996 0 0 0 417544 0 0 0 0 0 0 298498 0 0 0 137222 0 0 0 0 0 379701 0 0 0 0 0 0 0 0 177880 278881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276397 0 0 0 0 0 0 0 0 519895 0 0 0 0 0 0 0 401367 0 0 0 778085 0 0 0 0 0 0 507360 0 0 0 582589 0 0 0 0 0 833219 0 0 0 0 0 0 0 0 902107 674107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QFGKPVQVGIIIPK MGYG000000142_00004;MGYG000003695_01166;MGYG000002312_02616;MGYG000001338_01045;MGYG000001027_01800;MGYG000004296_01828;MGYG000000216_03624 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,3XYTN@572511|Blautia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 Methylenetetrahydrofolate reductase 1.0 metF 1.0 - 1.0 1.5.1.20 1.0 ko:K00297 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 1.0 M00377 1.0 R01224,R07168 1.0 RC00081 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MTHFR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylenetetrahydrofolate reductase [NAD(P)H]. MTHFR. A flavoprotein (FAD).-!-The enzyme catalyzes the reversible conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, playing an important role in folate metabolism by regulating the distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis.-!-This enzyme, characterized from Protozoan parasites of the genus Leishmania, is unique among similar characterized eukaryotic enzymes in that it lacks the C-terminal allosteric regulatory domain (allowing it to catalyze a reversible reaction) and uses NADH and NADPH with equal efficiency under physiological conditions. cf. EC 1.5.1.53, EC 1.5.1.54, and EC 1.5.7.1.-!-Formerly EC 1.1.1.68, EC 1.1.1.171, EC 1.1.99.15 and EC 1.7.99.5. (1) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH. (2) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Antifolate resistance;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 756352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QFHGYFNK MGYG000004681_01028;MGYG000003266_00909;MGYG000002947_00046;MGYG000002919_01817;MGYG000000188_01569;MGYG000001718_00229;MGYG000002970_01274;MGYG000001642_00447;MGYG000002775_00112 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CUFQ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 - 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QFHLVDSEHEINNLLK MGYG000002478_02180;MGYG000002560_01469;MGYG000000243_00722;MGYG000002291_01779;MGYG000001750_01197 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,2FM8A@200643|Bacteroidia,4AMZZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP 1.0 purA 1.0 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 6.3.4.4 1.0 ko:K01939 1.0 ko00230,ko00250,ko01100,map00230,map00250,map01100 1.0 M00049 1.0 R01135 1.0 RC00458,RC00459 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Adenylsucc_synt 1.0 - 1.0 - 1.0 - 1.0 - 0.8 adenylosuccinate synthase. succinoadenylic kinosynthetase. - GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 464038 316737 629577 236727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 639241 0 921101 707220 0 0 0 0 630826 0 0 0 218559 369492 251147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54752 0 0 0 0 0 0 0 0 172956 0 0 0 0 1178867 0 0 0 348844 940653 309972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213159 0 0 0 0 0 272647 0 0 0 0 0 0 0 0 0 0 0 0 102302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168808 0 0 0 0 0 0 0 0 0 71211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974520 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QFHNAYLK MGYG000002040_00997;MGYG000001300_02187;MGYG000003899_00641 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 336277 0 0 104621 0 0 229697 0 0 0 144875 0 0 0 0 0 378276 0 0 0 0 0 0 0 0 884276 0 0 0 0 2045535 0 0 2009559 0 1577217 2625242 0 2816889 0 0 1813526 0 2245130 1893554 0 0 0 3443410 0 0 1199142 0 1250642 2814935 2095504 0 0 0 0 0 0 0 2543620 0 2459455 1835990 0 0 0 0 564590 0 1236765 1004289 0 199006 0 0 1258257 0 0 0 0 0 0 1186771 0 0 638492 0 0 1510353 0 0 0 0 0 0 0 0 1833299 0 0 0 0 275480 0 0 231693 0 0 388573 0 0 0 0 2169721 0 0 757667 0 0 0 1547308 0 0 188516 0 323976 2123224 1845894 0 0 0 0 0 0 0 1919899 0 421740 0 0 107157 0 0 0 0 639642 695726 0 500622 0 0 484990 0 995525 873919 0 0 0 670822 0 0 125087 0 480984 872217 553844 0 0 0 0 0 0 0 700358 0 666285 620297 0 -(Gln->pyro-Glu)QFHNAYLR MGYG000000022_02013 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174768 0 0 0 0 371072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428369 0 0 0 0 495118 0 0 0 0 722655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1669241 0 0 0 0 1739378 0 0 0 0 1199084 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QFHNTFVK MGYG000004769_00464 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4H3YU@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1423021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QFM(Oxidation)ANQR MGYG000004748_03679;MGYG000003363_02290;MGYG000001346_01518;MGYG000002478_00798;MGYG000002470_01229;MGYG000000196_03990;MGYG000002561_02176;MGYG000001337_03888;MGYG000001313_00073;MGYG000003221_01994;MGYG000001461_00405;MGYG000000243_01970;MGYG000002455_03900;MGYG000004185_01162;MGYG000000236_01786 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,2FM1W@200643|Bacteroidia,4AKIE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QFMANQR MGYG000004748_03679;MGYG000003363_02290;MGYG000001346_01518;MGYG000002478_00798;MGYG000002470_01229;MGYG000000196_03990;MGYG000002561_02176;MGYG000001337_03888;MGYG000001313_00073;MGYG000003221_01994;MGYG000001461_00405;MGYG000000243_01970;MGYG000002455_03900;MGYG000004185_01162;MGYG000000236_01786 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,2FM1W@200643|Bacteroidia,4AKIE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 575083 0 0 0 796492 0 0 0 0 0 0 0 0 0 650814 0 0 0 0 0 0 0 0 0 0 0 0 575663 0 0 0 0 0 0 0 0 0 0 608529 0 0 0 1146107 0 0 0 0 0 0 0 0 0 500468 0 0 0 0 0 0 0 0 0 0 0 0 638953 0 0 0 0 0 0 0 0 0 0 280093 0 0 0 617973 0 0 0 0 0 0 0 0 0 167313 0 0 0 0 0 0 0 0 0 0 0 0 194119 0 0 0 0 0 0 0 0 0 0 236106 0 0 0 365941 0 0 0 0 0 0 0 0 0 420392 0 0 0 0 0 0 0 0 0 0 0 0 379315 0 0 0 0 0 0 0 0 0 0 359779 0 0 0 735885 0 0 0 0 0 0 0 0 0 189862 0 0 0 0 0 0 0 0 0 0 0 0 401281 0 0 0 0 -(Gln->pyro-Glu)QFNLM(Oxidation)FK MGYG000003366_01810;MGYG000001688_03818;MGYG000002523_01602;MGYG000000216_02240;MGYG000002298_01808;MGYG000002670_01474;MGYG000002937_00171;MGYG000001615_00144;MGYG000000002_01932;MGYG000001644_00341;MGYG000004196_01635;MGYG000003422_01231;MGYG000004839_00369;MGYG000000251_00298;MGYG000000031_02398;MGYG000002882_01752;MGYG000000348_01888;MGYG000003533_00387;MGYG000000378_00782;MGYG000000258_01693;MGYG000000371_00188;MGYG000004087_01279;MGYG000002116_00583;MGYG000002992_01229;MGYG000002794_00630;MGYG000000201_02682;MGYG000003256_02223;MGYG000003825_01449;MGYG000000416_00486;MGYG000001814_01722;MGYG000000354_00684;MGYG000000136_02286;MGYG000000119_01747;MGYG000004830_00903;MGYG000004487_00107;MGYG000003355_01218;MGYG000004475_00092;MGYG000000262_02744;MGYG000000223_03366;MGYG000001683_02052;MGYG000000142_02827;MGYG000000242_00227;MGYG000000501_00650;MGYG000000312_02403;MGYG000001500_00914;MGYG000000562_02504;MGYG000000462_01287;MGYG000002791_00657;MGYG000003533_00957;MGYG000001871_01158;MGYG000002057_00097;MGYG000004871_01776;MGYG000002279_02002;MGYG000002195_02035;MGYG000003694_01655;MGYG000004885_01325;MGYG000004735_00209;MGYG000004757_00072;MGYG000004271_01395;MGYG000000179_00115;MGYG000000249_01100;MGYG000000076_00068;MGYG000000193_01867;MGYG000001606_00310;MGYG000003498_00848;MGYG000002492_01703;MGYG000003535_01712;MGYG000000359_00712;MGYG000000133_02953;MGYG000003202_00086;MGYG000001711_01084;MGYG000003311_00453;MGYG000003427_01851;MGYG000002926_00944;MGYG000001913_01129;MGYG000000268_00696;MGYG000004733_01909;MGYG000003686_00223;MGYG000001319_00731;MGYG000000989_01980;MGYG000001764_00567;MGYG000000281_03413;MGYG000000212_00438;MGYG000000173_01055;MGYG000002149_01694;MGYG000002084_00804;MGYG000003147_00597;MGYG000002304_00986;MGYG000001733_00367;MGYG000000271_00389;MGYG000004525_01950;MGYG000001511_01429;MGYG000002720_01072;MGYG000000245_00871;MGYG000003486_02394;MGYG000002762_00453;MGYG000002212_01826;MGYG000001439_01577;MGYG000001622_02869;MGYG000000233_00373;MGYG000001781_01825;MGYG000003510_00241;MGYG000001651_00430;MGYG000003425_01035;MGYG000004869_04098;MGYG000002528_02207;MGYG000000198_00245;MGYG000000121_00703;MGYG000002517_01239;MGYG000004414_01227;MGYG000002715_00885;MGYG000001637_01168;MGYG000000252_02478 domain d__Bacteria 1.0 COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3WGTU@541000|Ruminococcaceae 0.2743362831858407 186801|Clostridia 0.8141592920353983 J 0.9911504424778761 Catalyzes the attachment of glycine to tRNA(Gly) 0.6460176991150443 glyQS 0.9734513274336283 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 0.8053097345132744 6.1.1.14 0.9911504424778761 ko:K01880 0.9911504424778761 ko00970,map00970 0.9911504424778761 M00359,M00360 0.9911504424778761 R03654 0.9911504424778761 RC00055,RC00523 0.9911504424778761 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 0.9911504424778761 - 1.0 - 1.0 - 0.9823008849557522 HGTP_anticodon,tRNA-synt_2b 0.9911504424778761 - 1.0 - 1.0 - 1.0 - 1.0 glycine--tRNA ligase. glycyl-tRNA synthetase. - ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). 0.9911504424778761 0.9911504424778761 0.9911504424778761 0.9911504424778761 Aminoacyl-tRNA biosynthesis 0.9911504424778761 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QFVEDDKILR MGYG000002492_01668 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 abc transporter atp-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K16786,ko:K16787 1.0 ko02010,map02010 1.0 M00582 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 1.0 - 1.0 - 1.0 ABC_tran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 3582480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284990 0 0 1653604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2194975 0 0 1839433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1071599 0 0 0 0 906810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1613234 0 0 0 0 0 0 0 818568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 904359 0 0 0 0 1588220 -(Gln->pyro-Glu)QFVVHR MGYG000003372_01707;MGYG000002494_00750;MGYG000002469_00977;MGYG000001292_01716;MGYG000002477_03920;MGYG000003683_00691 domain d__Bacteria 1.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,3WXKH@544|Citrobacter 0.5 1236|Gammaproteobacteria 0.5 U 0.5 Involved in the TonB-independent uptake of proteins 0.5 tolB 0.5 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 0.5 - 0.5 ko:K03641 0.5 - 0.5 - 0.5 - 0.5 - 0.5 ko00000,ko02000 0.5 2.C.1.2 0.5 - 1.0 - 1.0 PD40,TolB_N 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.5 0.5 0.5 0.5 0.5 none 1.0 0 0 430387 0 0 0 0 0 0 0 0 0 846471 0 0 0 0 234029 0 0 0 0 112500 0 0 0 0 282807 0 0 0 0 0 0 0 0 0 264315 0 0 948873 0 0 0 0 0 0 0 0 0 2287553 0 0 0 0 2019190 0 0 0 0 785142 0 0 0 0 1893205 0 0 1150830 0 697477 0 0 0 0 1389553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143337 0 0 0 0 548492 0 0 0 0 148631 0 0 0 0 202274 0 0 234205 0 0 0 0 0 0 0 0 0 129582 0 0 0 0 124959 0 0 0 0 0 0 0 0 0 0 0 0 206104 0 200222 0 0 0 0 165721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151452 0 0 0 0 0 -(Gln->pyro-Glu)QFYGSGFSDETYENAKK MGYG000001300_00301;MGYG000002223_00312 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Radical SAM domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,Radical_SAM,SPASM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507239 573251 615723 538587 0 555499 720138 0 662537 0 0 461654 0 0 0 0 711221 0 838803 555280 0 356543 0 558421 0 533997 683839 0 0 0 700720 0 489352 0 0 0 568139 452039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444527 0 0 502001 403884 0 0 0 0 0 0 0 0 0 347236 0 0 0 0 412723 0 0 0 0 0 0 0 0 501445 0 360833 0 0 0 0 288560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGADIIAVIR MGYG000002794_00763;MGYG000002926_00664;MGYG000002882_00085;MGYG000002720_00861;MGYG000002931_00001;MGYG000002143_01959;MGYG000001733_00672;MGYG000004196_01673;MGYG000004487_00297;MGYG000002086_01355 domain d__Bacteria 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 0.9 186801|Clostridia 0.9 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 0.9 kamD 0.9 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 108327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGADVIAVIR MGYG000000099_02239;MGYG000003801_01081 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,267NE@186813|unclassified Clostridiales 0.5 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 0.5 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 73823 0 0 0 0 0 0 220385 110927 0 0 0 0 0 0 0 0 0 0 192542 0 0 0 0 0 181473 120499 0 0 0 0 0 0 100396 0 0 208138 0 601089 0 0 0 0 0 1432054 456960 814829 0 0 0 0 0 0 0 0 0 0 711307 0 0 0 0 0 624870 610539 0 0 0 0 0 0 585041 0 749521 502450 0 1760482 0 0 0 0 0 439513 1336895 286226 0 0 0 0 0 0 0 0 0 0 1422258 0 0 0 0 0 818454 1366830 0 0 0 0 0 0 1462204 0 451497 933571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102161 105231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGANLQESNDKMFER MGYG000002478_00270;MGYG000000243_02147;MGYG000002171_01599 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,2FM2T@200643|Bacteroidia,4AKYC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 maeB 1.0 - 1.0 1.1.1.38,1.1.1.40 1.0 ko:K00027,ko:K00029 1.0 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 1.0 M00169,M00172 1.0 R00214,R00216 1.0 RC00105 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,PTA_PTB,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 malate dehydrogenase (oxaloacetate-decarboxylating). | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. | The enzyme catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate, cf. EC 1.1.1.38 and EC 1.1.1.39. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. | (1) (S)-malate + NADP(+) = CO2 + NADPH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Metabolic pathways;Two-component system;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 596536 0 700792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 650866 0 0 0 0 518433 0 0 395914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGASKDEANDIK MGYG000000233_00504;MGYG000000255_02155 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 504045 0 0 453495 0 371840 401970 725132 572776 440130 0 0 0 681790 0 0 0 0 471755 593103 0 684487 0 517463 0 441064 520635 0 658845 514930 0 351998 0 1057351 0 654085 420002 0 2109860 0 1984297 2871905 0 2199462 2086360 2815016 2411587 2137863 0 0 0 2320638 0 0 0 0 2015460 1470692 0 1558367 0 1600941 0 1716487 1743562 0 1700381 2126593 0 1770890 1850806 1867201 0 1588215 1893126 1588424 529459 0 0 223998 0 0 0 201410 399663 603395 0 0 0 393391 0 0 0 0 0 167212 0 0 0 0 0 627849 712878 0 449725 526151 0 225614 0 716953 0 675512 385982 0 1009026 0 1110791 962676 0 919504 1515701 1473655 1112865 1265542 0 0 0 1078784 0 0 0 0 1216360 874117 0 1330152 0 993388 0 1310201 1225190 0 1105431 863489 0 944213 1012240 1463186 0 1145337 1052646 950040 0 0 0 165019 0 195702 143379 283892 0 0 0 0 0 0 0 0 0 0 451725 0 0 467584 0 0 0 172154 0 0 210685 0 0 257995 0 687245 0 0 0 339522 -(Gln->pyro-Glu)QGASKDEANDIKTK MGYG000000233_00504;MGYG000000255_02155 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 222438 0 0 427590 0 0 0 0 0 0 0 0 226878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427922 0 0 509196 0 0 507224 0 0 0 0 0 645089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203774 0 0 325016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254841 0 0 612670 0 0 400235 0 0 0 0 0 286626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGASKEEANDIK MGYG000001199_02683;MGYG000000242_00771 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133701 0 0 0 0 176284 0 0 0 0 166158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217452 0 0 0 0 569588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1864513 0 0 0 0 2337755 0 0 0 0 1849815 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGDDIEILNPEWHIATLGEGAK MGYG000001300_02186;MGYG000001255_02105 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WGUM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 - 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGDSDTVSLK MGYG000000242_00772 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366708 0 0 0 0 277802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516224 0 0 0 0 446817 0 0 0 0 308711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2824348 0 0 0 0 2641513 0 0 0 0 2488666 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGEAATEEASERA MGYG000001490_00318;MGYG000003452_00078;MGYG000000756_00970;MGYG000003683_01140;MGYG000002395_00348 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 590072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386610 0 0 0 0 356648 0 0 1054890 0 0 461706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209291 0 910573 0 0 0 0 0 0 1257185 0 946275 0 0 0 0 1519494 0 0 531547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1138513 0 0 0 0 346289 0 0 0 0 0 408554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 876601 0 705555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGEEFPQDPKEQLIGAVK MGYG000000084_02524;MGYG000004866_01031;MGYG000001157_01952 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723686 0 0 0 0 0 0 0 0 0 189440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 589019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGEGVAATIVDLGNR MGYG000002455_02701 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,2FMIU@200643|Bacteroidia,4APG1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the conversion of L-arabinose to L-ribulose 1.0 araA 1.0 - 1.0 5.3.1.4 1.0 ko:K01804 1.0 ko00040,ko01100,map00040,map01100 1.0 - 1.0 R01761 1.0 RC00516 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Arabinose_Iso_C,Arabinose_Isome 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-arabinose isomerase. L-arabinose ketol-isomerase. Requires a divalent metal ion (the enzyme from the bacterium Escherichia coli prefers Mn(2+)).-!-The enzyme binds beta-L-arabinopyranose and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene-diol mechanism.-!-The enzyme can also convert alpha-D-galactose to D-tagatose with lower efficiency. beta-L-arabinopyranose = L-ribulose. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 628380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456666 0 0 0 0 336720 0 0 0 0 166813 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGELDDKQLEDGLTEKK MGYG000000224_00341;MGYG000000105_02189;MGYG000003681_00297;MGYG000001313_01991 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,2FN0C@200643|Bacteroidia,4AKKG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG19144 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 419515 0 0 397549 0 0 0 0 0 691214 0 546210 0 479043 0 0 417385 245374 0 0 0 0 218018 0 0 456199 0 0 0 0 0 0 0 0 492505 0 494115 0 489814 0 0 526392 0 0 0 0 0 681160 0 725763 0 541763 0 0 567207 977943 0 0 0 0 847556 0 0 485164 0 1181261 0 0 0 0 0 0 600353 0 572886 0 294075 0 0 200970 0 0 0 0 0 335946 0 304195 0 325358 0 0 434177 0 0 0 0 0 0 0 0 230306 0 0 0 0 0 0 0 0 446106 0 178329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGENRPSGGHEIVLKPIEGVR MGYG000000255_01680 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,27UZQ@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 323453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165759 0 0 0 0 0 0 0 0 0 0 0 0 407255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386684 0 0 0 0 0 0 0 0 0 0 373807 0 227436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271572 0 0 0 0 0 0 0 0 0 0 0 0 113700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124863 0 0 0 0 0 0 0 0 0 0 150717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGEVITAEVVR MGYG000003170_00225;MGYG000001410_02390 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella 1.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,4PQ3M@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572928 0 0 0 -(Gln->pyro-Glu)QGFEVYTTAEAAK MGYG000000245_00071;MGYG000000271_00298;MGYG000004271_02052 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 1.0 186801|Clostridia 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGFYNKDIITESIKR MGYG000003697_02156 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0524@1|root,COG0524@2|Bacteria,4NGFK@976|Bacteroidetes,2FN72@200643|Bacteroidia,22WT2@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 pfkB family 1.0 ydjH_1 1.0 - 1.0 2.7.1.4 1.0 ko:K00847 1.0 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 1.0 - 1.0 R00760,R00867,R03920 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructokinase. D-fructokinase. - ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways;Fructose and mannose metabolism;Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769359 0 0 822797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511952 0 417077 0 0 0 0 0 0 0 0 676908 0 0 0 0 419149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGGEVVGNHTR MGYG000002517_01765 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia 1.0 186801|Clostridia 1.0 L 1.0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage 1.0 recA 1.0 - 1.0 - 1.0 ko:K03553 1.0 ko03440,map03440 1.0 M00729 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03400 1.0 - 1.0 - 1.0 - 1.0 RecA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Homologous recombination 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGGIGFIHK MGYG000002485_02170;MGYG000004893_01198;MGYG000004828_01108;MGYG000001327_01268 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,378I3@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 297105 0 0 0 0 0 0 598792 0 0 0 0 0 216813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 441619 0 471013 0 0 467177 0 0 1123716 0 0 0 0 0 0 1078369 0 0 0 0 0 1135175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 940250 0 772377 0 0 883869 0 0 150782 0 0 0 0 0 0 363370 0 0 0 0 0 269770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311732 0 0 562299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 622235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585842 -(Gln->pyro-Glu)QGGIGIIHK MGYG000004847_02037;MGYG000000271_00603;MGYG000002901_00218;MGYG000003149_00433;MGYG000000087_02531;MGYG000000213_01314;MGYG000000562_02421;MGYG000000171_02641;MGYG000001367_02921;MGYG000004879_00512;MGYG000004271_01872;MGYG000002517_01047;MGYG000003783_01872;MGYG000001645_00506;MGYG000002492_02315;MGYG000000489_00932;MGYG000003486_02497;MGYG000000080_01161;MGYG000002528_02466;MGYG000000204_01913;MGYG000000212_00040;MGYG000001319_00739;MGYG000000136_01100;MGYG000004250_01264;MGYG000004735_02781;MGYG000002966_01598;MGYG000000146_01483;MGYG000002992_01076;MGYG000000233_01272;MGYG000001193_00608;MGYG000000164_00891;MGYG000000205_01225;MGYG000001315_00701;MGYG000000028_00786;MGYG000001186_00833;MGYG000000127_02910;MGYG000000206_01855;MGYG000000187_01407;MGYG000000133_00306;MGYG000000142_02314;MGYG000004740_01385;MGYG000003984_01817;MGYG000000356_01714;MGYG000002670_00089;MGYG000000263_02824;MGYG000002247_00883;MGYG000004642_00172;MGYG000003694_03060;MGYG000000193_00312;MGYG000001338_00214;MGYG000004869_03402;MGYG000000301_00957;MGYG000004884_01768;MGYG000000989_02246;MGYG000000252_03031;MGYG000001748_02097;MGYG000000262_01414;MGYG000001314_02149;MGYG000003782.1_00452;MGYG000004785_01919;MGYG000002279_00396;MGYG000000077_00487;MGYG000001623_01024;MGYG000000251_01328;MGYG000002298_01715;MGYG000004285_01802;MGYG000001637_01052;MGYG000002835_00811;MGYG000000002_02500;MGYG000001219_01350;MGYG000003366_01162;MGYG000001571_02994;MGYG000003695_02134;MGYG000000092_00381;MGYG000002985_01150;MGYG000004087_02343 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia 0.2236842105263158 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 2354011 2793765 2373496 1641613 3086858 3487239 1315804 3207496 1936679 2688630 2538011 2952400 3657663 2965391 2747130 3117380 3085105 2852382 2196633 2663577 3142663 3503856 2111843 1479558 2712302 1933601 2398627 2813588 2348706 2607921 1581039 3129233 2243973 2355399 2587041 2086207 2035847 2651530 1935103 2848634 1719858 1543140 1676971 1300688 1525492 2091387 2086048 1732423 1361265 1379121 1660233 1191243 1297272 1258882 1541997 2198146 1546344 1508735 1218233 985276 1294167 1642043 1665710 1541150 1821422 2378402 2283609 1536911 3115447 1738622 1913653 2354310 2633593 2085736 1846132 2415449 3848944 6823784 3896597 4110785 1949946 3097082 2326064 3859613 2950933 3281389 2883566 2618110 3310058 3668202 3880292 3629639 3661575 1861430 4039793 3669915 3202191 0 2300999 2793549 4773181 3576364 4467507 3004935 3663661 4000317 2542309 6015991 5154041 4777307 4299816 2472929 3331288 3490374 3270636 0 1523750 3677503 3613528 3002410 3047463 3990864 3626818 3884848 0 3283667 2806076 4293938 3598465 3392213 3758971 0 3363519 3657257 2620884 1758864 575924 1608547 3478602 3358540 4166438 183133 5034211 3781020 3775231 3994388 2468360 1956357 3752591 2927935 3386171 594756 3239069 4048926 4978246 4162388 1789030 3069053 4584077 3221794 3030462 4686013 3170069 4114659 2072122 4204062 4025018 2768451 3354198 1437978 3268103 1869646 4080087 4308902 2371089 2652000 3568757 2575654 3368659 2559366 4233660 1708816 3706767 4919636 6071032 4035456 3102825 3632353 3218146 4083149 -(Gln->pyro-Glu)QGGITLMMDR MGYG000002515_03615;MGYG000002494_01532;MGYG000002534_04857 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,3WVBR@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iJN746.PP_4678,iLF82_1304.LF82_1103 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319843 0 296905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 96646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGGLGIIHK MGYG000001412_04889;MGYG000000271_00603;MGYG000001338_00214;MGYG000002528_02466;MGYG000001193_00608;MGYG000000164_00891;MGYG000002835_00811;MGYG000000262_01414;MGYG000002279_00396 domain d__Bacteria 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,267WW@186813|unclassified Clostridiales 0.2222222222222222 186801|Clostridia 0.8888888888888888 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 0.8888888888888888 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4863385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGGLQFIDEVK MGYG000001364_02756;MGYG000001835_01810;MGYG000002478_00801;MGYG000004763_00924;MGYG000003693_00191;MGYG000000243_01973;MGYG000001783_02408;MGYG000001306_02658 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia,4AKVK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 801066 0 0 0 0 954380 0 0 0 0 881008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGGSNRETFTVR MGYG000004719_02005;MGYG000002517_01927;MGYG000002212_02160;MGYG000004271_01601;MGYG000000271_00796 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia 0.8 186801|Clostridia 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 - 1.0 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGGVRESLEDKTMNLAK MGYG000002478_00968;MGYG000004797_01273 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGGVRESLEEK MGYG000001783_00644;MGYG000000243_02351 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGHDVKGPTAAGNSVAK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 1048136 3012378 1242880 450331 3857600 2352282 120811 1817552 443817 1988358 1298381 1534742 3474616 1042135 1583170 4089853 1240142 0 1245941 1507067 945885 3503353 0 514592 1724538 789290 688694 0 581254 1121550 792146 2238570 753316 1038400 980724 368086 583753 1239490 2647329 2722791 528109 1157254 828566 1433811 3435838 1246815 1651791 951122 611435 565947 1200505 737456 932769 637155 875727 0 1425443 1911382 1158658 846329 0 2368726 1142754 1619778 1839869 0 2929851 1047636 1955213 1112980 642182 2166599 1908061 2358819 1365609 754974 5028162 10885980 1540305 6639471 884969 5814097 1086051 6356866 1263453 4579819 1923452 2837305 4006930 3369390 5340693 4261309 3747388 0 6835743 4856076 3381408 8329198 0 2984427 6039179 4150647 7206797 0 805882 3748773 1728629 5756074 3446313 7380607 2043283 1632157 3585816 1329733 2283833 2399083 1609351 2931797 1915029 3460896 3327410 2335519 2381260 4927846 1918278 1529164 3506828 2544117 2394527 4108528 3391638 0 1817479 3184939 1575435 2286189 0 2011498 2449744 966511 2864650 0 1901264 2533874 334308 1725552 1876890 1818710 2428062 1985760 1398039 1362728 2036041 3268825 5650694 2651269 5835598 3502890 1196026 1688696 2570726 3480658 5703270 2605002 6620983 1843763 1841325 3854461 2555647 0 2751462 2009720 1365725 2854620 0 1997670 2066879 2808784 1805645 0 608039 2095943 5483511 4774754 5530737 2548670 2722913 2784960 2963824 4845140 -(Gln->pyro-Glu)QGHDVKGPTAAGNSVAKLDQLNISN(Deamidated)GTLYNQK MGYG000000262_02730 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 963145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGHRQPYTK MGYG000002720_00243;MGYG000001658_02153;MGYG000002057_00937;MGYG000003686_02150;MGYG000001502_03046;MGYG000003819_01744 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,2N7IB@216572|Oscillospiraceae 0.6666666666666666 186801|Clostridia 0.8333333333333334 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 - 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGIAKLPEGNDYEQAAK MGYG000002293_00078;MGYG000001770_00051 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the transketolase family 1.0 tkt 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1576901 0 0 0 0 2386996 0 0 0 0 2129499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGIAVDKDYYYVSDTK MGYG000003681_01837 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG3391@1|root,COG3391@2|Bacteria,4NJJN@976|Bacteroidetes,2FNI0@200643|Bacteroidia,22Z3Y@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 amine dehydrogenase activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 529502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448365 0 0 582393 0 0 0 0 612548 0 0 0 0 0 0 0 0 0 924852 0 0 0 0 0 0 482299 602534 0 0 0 0 0 0 0 0 0 510259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395663 468855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGIGLVGYGQRDPVVEYK MGYG000000212_01327;MGYG000000301_01158;MGYG000000133_00962 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3XYPH@572511|Blautia 1.0 186801|Clostridia 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane 1.0 secA 1.0 - 1.0 - 1.0 ko:K03070 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 1.0 - 1.0 - 1.0 Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW 1.0 - 1.0 - 1.0 GT41 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169438 0 0 0 0 195276 0 0 98367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228191 0 0 0 0 220395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 536634 0 0 0 0 272604 -(Gln->pyro-Glu)QGIHPNYVDC(Carbamidomethyl)TITC(Carbamidomethyl)AC(Carbamidomethyl)GNVIK MGYG000001300_00389;MGYG000003166_00009;MGYG000002274_00606;MGYG000002651_01024;MGYG000002040_00344;MGYG000000022_01287 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3WKI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds the 23S rRNA 1.0 rpmE 1.0 - 1.0 - 1.0 ko:K02909 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L31 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 483244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGIHPNYYQAK MGYG000000205_01476;MGYG000000233_00887;MGYG000000255_02664 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,220Y9@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 50S ribosomal protein L31 1.0 rpmE 1.0 - 1.0 - 1.0 ko:K02909 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L31 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 318934 0 0 0 0 426951 0 0 0 512305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395960 0 0 372431 0 676962 0 0 0 493569 0 0 0 0 902635 1068073 0 0 495653 0 0 768615 0 0 0 0 0 0 0 0 374904 596671 0 0 0 0 0 0 823869 0 0 365786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGILDPDTLTKEER MGYG000000198_04022 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,21XTX@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 FAD dependent oxidoreductase 1.0 lhgO 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 1079831 0 335921 863431 651654 0 392075 811018 532882 944466 0 0 679947 1030185 714162 390045 576518 0 839930 1308686 737948 0 0 0 0 949814 888956 0 757957 892219 0 0 0 451309 919864 874518 734131 280129 250855 0 0 356736 0 0 418191 0 403793 420263 0 0 483953 382795 0 0 0 0 301969 376674 426425 0 0 0 0 343249 640438 0 717709 0 0 0 0 0 404309 0 424310 0 1145454 0 689649 1277466 0 0 761365 877711 1034479 795139 0 0 703144 1031421 1161400 745830 629535 0 1092188 1111052 1015222 0 0 0 0 860318 1186519 0 1078301 1003052 0 0 491377 1220038 575198 688435 823606 568254 192285 0 0 0 0 0 456026 0 0 0 0 0 0 0 0 217267 0 0 0 0 0 0 0 0 0 0 0 0 0 250938 0 0 0 0 0 0 0 0 0 0 184407 0 0 0 365835 206146 318598 322596 0 0 0 0 0 0 380157 0 0 0 441090 0 0 0 0 170995 0 0 0 363742 0 0 0 0 0 298547 0 0 -(Gln->pyro-Glu)QGIQWMIADMATK MGYG000004736_01082 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Evtepia|s__Evtepia sp004554585|m__MGYG000004736 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WI1F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGKFDFC(Carbamidomethyl)R MGYG000000133_00227 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,36EHU@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 Family 5 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 205175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135516 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 834288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1147215 0 0 0 0 700127 -(Gln->pyro-Glu)QGKFPGLR MGYG000002438_02078 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,2FN0C@200643|Bacteroidia,22YIM@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG19144 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181288 0 0 0 0 0 0 0 0 0 0 0 0 212950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736235 0 412887 0 0 0 0 0 0 0 0 0 0 168138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385574 0 0 0 0 0 0 0 0 0 0 0 0 215836 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 792248 0 732586 0 0 0 0 0 0 0 0 0 0 1738609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2972073 0 2257930 0 0 0 0 0 0 -(Gln->pyro-Glu)QGKIDFKVDK MGYG000000196_03979;MGYG000001370_01685;MGYG000000243_01983;MGYG000001835_01818;MGYG000002478_00809;MGYG000001345_04689 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,2FNKI@200643|Bacteroidia,4ANG1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGKPLEDLSLADLQK MGYG000002494_01893 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,3XMS6@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 argininosuccinate lyase 1.0 argH 1.0 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.3.1.1,4.3.2.1 1.0 ko:K01755,ko:K14681 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230 1.0 M00028,M00029,M00844,M00845 1.0 R00259,R01086 1.0 RC00004,RC00064,RC00445,RC00447 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ASL_C2,Acetyltransf_1,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 amino-acid N-acetyltransferase. | argininosuccinate lyase. N-acetylglutamate synthase. | omega-N-(L-arginino)succinate arginine-lyase. Also acts with L-aspartate and, more slowly, with some other amino acids. acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate. | 2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692773 465747 0 0 915932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1452265 0 841564 0 0 0 0 0 0 0 0 474034 0 0 0 0 345094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGKPQVNYK MGYG000000196_03987;MGYG000001659_00198;MGYG000001599_01853;MGYG000002293_00507 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia,4AKVK@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520235 0 0 0 292567 0 0 0 0 323645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 991457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 735993 0 0 0 571577 0 0 0 0 956304 0 0 1666447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1223919 0 0 0 1617881 0 0 0 0 2051642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGKYDDAVNAYTK MGYG000000013_00602 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp902362375|m__MGYG000000013 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,4ANQH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 758814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3167185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGLDELIDK MGYG000000179_02173 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,21XTX@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 FAD dependent oxidoreductase 1.0 lhgO 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 145982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79190 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 614056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 667220 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGLDFVR MGYG000000028_00488 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus_A|m__MGYG000000028 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD,NAD_binding_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 734602 0 236077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGLDHVC(Carbamidomethyl)SAAR MGYG000002517_00257 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 234739 464287 0 0 301528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5330038 0 0 5554411 2417426 417700 4042779 7745857 10447838 1945957 1634185 2707444 0 7984101 6836794 0 3616313 0 5950350 7875172 3321516 0 0 769029 7553920 9334462 6391525 0 0 3444581 0 0 0 5549636 6741260 6196456 10220210 1501201 5775489 0 5007572 0 3433033 4001522 7179027 5627694 7565352 7667044 5175321 4649669 0 8456655 8028817 4016505 6161418 0 4873320 4328752 5645215 3235362 0 3679524 10908099 10989126 5692478 0 0 4094624 4605037 0 5057469 8226158 6637948 10809641 8655897 6060144 -(Gln->pyro-Glu)QGM(Oxidation)LAGLDKLADTVK MGYG000003683_00853;MGYG000000756_00212;MGYG000002395_00609;MGYG000002459_00653 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CZJK@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGMIDEKTALER MGYG000004797_01193;MGYG000002478_03849 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGNALGWATAGGSGFR MGYG000002515_03180;MGYG000002385_00373;MGYG000001708_01489;MGYG000002534_00415;MGYG000001466_00767;MGYG000002415_02008;MGYG000002476_04062;MGYG000002525_03273;MGYG000002514_02441;MGYG000002536_00956;MGYG000002323_00409;MGYG000003386_02373;MGYG000002513_02354;MGYG000002506_02938;MGYG000002477_00164 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,3WY9K@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 153720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242673 0 0 0 0 516202 0 0 0 0 1173111 0 0 443786 992637 0 0 0 781596 0 0 655444 0 768886 0 0 1280157 0 776050 981335 600712 0 0 872749 0 0 0 0 451866 0 0 407770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 420547 0 0 0 0 0 0 0 0 0 324284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGNLLELAVEAAK MGYG000003279_00971;MGYG000004658_00971;MGYG000000003_01875 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,22U75@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 B12 binding domain 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 6427406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 888992 0 0 6082341 0 0 0 0 0 0 7663356 0 0 10275611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3874 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4197654 0 0 0 0 0 0 0 3616459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1517513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGNQEAAPAEDAANA MGYG000002272_01435;MGYG000001300_00246;MGYG000002223_00595;MGYG000002274_00630;MGYG000002545_00160 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGNTELQQK MGYG000002506_00187;MGYG000003390_02380;MGYG000003360_01604;MGYG000003372_02171;MGYG000002494_00886;MGYG000002323_01448;MGYG000003883_00530 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,1RPXK@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 ET 1.0 belongs to the bacterial solute-binding protein 3 family 1.0 artI 1.0 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 1.0 - 1.0 ko:K09996,ko:K09997,ko:K10014 1.0 ko02010,map02010 1.0 M00226,M00229 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.3.1,3.A.1.3.3 1.0 - 1.0 iLF82_1304.LF82_0153,iNRG857_1313.NRG857_03895,iPC815.YPO1351 1.0 SBP_bac_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 144780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 918982 0 232431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGQIWIR MGYG000002281_02268;MGYG000002549_02918;MGYG000001345_04706;MGYG000000196_03996;MGYG000003693_00200;MGYG000004763_00933;MGYG000000243_01964;MGYG000001346_01512;MGYG000001313_00067;MGYG000001378_05020;MGYG000002560_00243;MGYG000001599_01844;MGYG000002561_02182;MGYG000000105_02011;MGYG000002455_03906;MGYG000000054_03865;MGYG000000098_01995;MGYG000003256_00317;MGYG000002478_00792;MGYG000002933_02454;MGYG000001370_01702;MGYG000003312_02984;MGYG000001364_02747;MGYG000000013_02229 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,2FRZE@200643|Bacteroidia,4AKTM@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs 1.0 rplP 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02878 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 341935 0 405846 315482 0 248727 374068 479609 0 538926 571258 304561 469480 336165 341210 308896 269682 200000 589180 0 544887 392878 350099 522980 345221 501822 0 277881 0 0 0 0 345969 546039 0 0 407657 324507 356806 0 517176 504118 0 344718 498412 676211 0 565564 679844 562964 155095 472835 486392 483508 377870 457970 463023 0 299641 470823 585775 357147 347246 498522 0 381936 0 0 0 363172 386683 269395 0 0 454994 340186 97581 0 334278 490046 0 288749 326305 265580 0 244741 564312 470343 367626 327877 315848 342760 80960 132352 373606 0 281622 261888 111187 494052 298533 215740 0 386420 0 0 0 89203 120721 353809 0 0 106186 375737 90378 0 170060 202166 0 191908 213115 277639 0 191346 353492 255447 387407 84801 293004 308599 188026 119954 256921 0 95772 184976 148969 82407 0 107058 0 0 0 0 0 351156 412268 298230 0 0 330347 264645 86962 0 190426 85493 0 362583 243737 255953 0 320196 556865 210597 336294 87877 87494 296328 237288 458675 315143 0 71899 154899 83048 212932 183254 194103 0 574367 0 0 0 191355 197457 405368 0 0 253888 253650 -(Gln->pyro-Glu)QGQLLMTR MGYG000000077_02469;MGYG000000262_02236 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,25UTQ@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 etfA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107852 0 0 143380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298798 0 0 0 0 0 0 0 0 0 0 0 0 384626 0 0 900109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 590017 0 0 0 0 0 792434 0 0 0 0 588750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGQLWIR MGYG000002291_02248;MGYG000002549_02918;MGYG000001345_04706;MGYG000000196_03996;MGYG000004763_00933;MGYG000000243_01964;MGYG000001346_01512;MGYG000001433_02283;MGYG000001378_05020;MGYG000001599_01844;MGYG000004185_01156;MGYG000000105_02011;MGYG000002455_03906;MGYG000000098_01995;MGYG000002478_00792;MGYG000000013_02229 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,2FRZE@200643|Bacteroidia,4AKTM@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs 1.0 rplP 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02878 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 508634 0 0 0 0 273676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286469 0 0 0 0 97996 0 0 0 0 0 0 -(Gln->pyro-Glu)QGQVWIR MGYG000004629_00397;MGYG000001056_01156;MGYG000002603_01760;MGYG000001975_01109;MGYG000003697_01461;MGYG000003374_01448;MGYG000002108_01886;MGYG000002293_00498;MGYG000001770_00602;MGYG000003287_00278;MGYG000002080_00548;MGYG000002834_00447;MGYG000000215_01907;MGYG000003353_02087 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,2FMYX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 1.0 rpsC 1.0 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02982 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106685 0 0 0 0 126167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 873658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 780838 0 0 0 0 1034837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGSIRAPQWTGGGVVFAPVPR MGYG000002298_00329;MGYG000001338_02806 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGSTRAPQWTHGGVVFAPVPR MGYG000004271_00017;MGYG000002517_02872;MGYG000000271_01062 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGTGIKPGDLK MGYG000003697_01173 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AWE5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 834742 0 0 0 0 638006 0 0 0 0 602173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371112 0 0 0 0 256842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2290963 0 0 0 0 2481639 0 0 0 0 2514286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775408 0 0 0 0 500644 0 0 0 0 612041 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGTQSALTR MGYG000004487_01021;MGYG000002964_01300;MGYG000004246_00716;MGYG000001476_03271;MGYG000002707_00964;MGYG000001193_00545;MGYG000003819_01159;MGYG000001675_00231;MGYG000004784_00635;MGYG000000099_02400;MGYG000002143_00708;MGYG000001616_02450;MGYG000001733_00032;MGYG000003686_01083;MGYG000000743_00443;MGYG000002159_00259;MGYG000003589_01463;MGYG000001576_02390;MGYG000002882_01831;MGYG000002057_00234;MGYG000004736_00666;MGYG000004124_01019;MGYG000000258_00282;MGYG000000036_00624;MGYG000002934_00474;MGYG000002115_00710;MGYG000004196_00637;MGYG000000392_01460;MGYG000002926_00535;MGYG000002944_01721;MGYG000001500_00883;MGYG000003581_01700;MGYG000001781_02370;MGYG000002116_01180;MGYG000004201_00826;MGYG000004727_00006;MGYG000004831_00879;MGYG000002229_01222;MGYG000002523_01978;MGYG000002794_00540;MGYG000002953_00592;MGYG000004482_00988;MGYG000003409_02387;MGYG000002857_00040;MGYG000000328_00214;MGYG000003453_00779;MGYG000003770_00994;MGYG000002727_02380;MGYG000004276_01040;MGYG000001502_00411;MGYG000001824_00247 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,2N6EK@216572|Oscillospiraceae 0.49019607843137253 186801|Clostridia 0.9607843137254902 J 1.0 Forms part of the polypeptide exit tunnel 0.5098039215686274 rplD 1.0 - 0.9607843137254902 - 1.0 ko:K02926 0.9607843137254902 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 0.9607843137254902 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGVDGDHVDYTNQSHPV MGYG000001300_00241 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 734251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGVGTGSC(Carbamidomethyl)NLIFTK MGYG000000140_01408;MGYG000000076_03383;MGYG000002024_01702 domain d__Bacteria 1.0 2FJFS@1|root,34B5D@2|Bacteria,1W0D9@1239|Firmicutes,24WID@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 430917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1355260 0 0 0 0 2179691 0 0 0 0 1576905 3110605 0 0 0 0 3279718 0 1398378 0 0 3630453 0 0 0 0 0 0 0 1450277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 591809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290380 0 0 0 0 0 0 0 0 0 0 0 0 0 395716 0 0 0 0 385321 518081 0 0 0 0 483494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGVM(Oxidation)HSR MGYG000000271_00943;MGYG000004414_01832;MGYG000004271_01186 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Acetyl-CoA hydrolase transferase 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGVPADQLR MGYG000004158_00682 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister invisus|m__MGYG000004158 1.0 COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H22W@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 bhbA 1.0 - 1.0 5.4.99.2 1.0 ko:K01848 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00375,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGVSADKLR MGYG000004769_01826;MGYG000000591_01064;MGYG000002659_00371;MGYG000001365_01210 family d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae 1.0 COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H22W@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 bhbA 1.0 - 1.0 5.4.99.2 1.0 ko:K01848 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00375,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 715135 0 0 0 0 0 0 0 0 0 0 345907 0 0 638801 0 485590 1580680 0 0 0 0 0 0 0 131390 648673 0 0 0 0 0 0 0 0 0 0 0 2861563 0 0 1788651 0 0 0 2873065 0 3108188 0 2923468 0 0 0 0 0 0 0 0 0 0 3086945 0 2994328 0 0 1499342 0 0 0 0 0 2203297 1813158 0 2268289 0 2942850 0 0 3475151 0 0 0 2279005 0 2299898 0 2332695 0 0 2080480 0 1551224 2753754 0 2586270 0 992342 2473393 2176911 2046319 1319585 2841350 0 0 0 0 0 0 0 516252 0 0 450755 911629 0 0 0 0 0 0 786654 0 666920 0 298684 0 0 0 0 188376 1053436 0 809566 461266 0 671399 1174076 907684 0 1107271 1220822 0 0 0 0 0 1332181 1891821 0 2220660 1376501 1520002 0 0 1165715 0 0 0 1110889 0 1191559 2341924 1120509 0 0 1180721 2110721 1412989 1145172 0 733109 1547327 1283779 1125502 1712749 2148742 1520588 1320273 1602829 0 0 2150456 -(Gln->pyro-Glu)QGVSKDEAEDVK MGYG000000179_05048 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2717679 0 863553 2173539 0 684711 0 0 2321279 2511909 0 1636688 0 3569466 2939517 1109738 2175198 0 2654333 0 0 1539471 0 1241391 1975523 4223226 2458032 0 0 2486861 0 0 503431 2605245 0 3683138 2908601 1281751 -(Gln->pyro-Glu)QGVSKDEAEDVKAK MGYG000000179_05048 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 228188 0 91747 256495 0 0 0 0 263777 277571 0 0 0 0 78094 0 215530 0 256212 0 0 0 0 0 0 103032 195509 0 0 0 0 0 0 0 0 176303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175865 0 0 104276 0 127943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 160330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1448907 0 950216 1918379 0 0 0 0 1790978 1604476 0 0 0 1236640 2073172 0 1580628 0 1430262 2032512 0 0 0 0 0 2642764 1527141 0 0 0 0 0 326436 1241575 0 2281790 2078236 984306 -(Gln->pyro-Glu)QGVSKDEAEDVKAKLEAEGAK MGYG000000179_05048 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260171 0 0 0 0 0 0 0 0 0 0 0 0 82791 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 860358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 864891 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QGVSKEEAEDVK MGYG000000198_05826 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1124724 0 0 0 0 0 0 0 0 0 0 0 0 1008550 659176 0 0 0 0 0 0 0 0 0 0 797630 0 0 0 688105 0 0 0 0 623053 1003035 874385 0 496586 0 0 0 0 0 0 0 0 0 0 0 0 594781 397633 0 0 0 0 0 0 0 0 0 0 444629 0 0 0 284492 0 0 0 0 340754 440727 401701 0 1178729 0 0 0 0 0 0 0 0 0 0 0 0 1265638 1269379 0 0 0 0 0 0 0 0 0 0 735141 0 0 0 1038303 0 0 0 0 335549 1177677 1002429 0 634940 0 0 0 0 0 0 0 0 0 0 0 0 607416 348434 0 0 0 0 0 0 0 0 0 0 531639 0 0 0 514009 0 0 0 0 209112 207690 469937 0 321675 0 0 0 0 0 0 0 0 0 0 0 0 0 249354 0 0 0 0 0 0 0 0 0 0 485288 0 0 0 416898 0 0 0 0 400424 297992 594477 0 -(Gln->pyro-Glu)QGYPIGC(Carbamidomethyl)K MGYG000002323_00398;MGYG000003372_01982;MGYG000000235_04528;MGYG000002515_03191;MGYG000002494_02457;MGYG000000093_01127 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,3X0U0@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits 1.0 rplE 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02931 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L5,Ribosomal_L5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2044655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHAIAAGK MGYG000001300_02022;MGYG000003166_01134 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WG9P@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily 1.0 purB 1.0 - 1.0 4.3.2.2 1.0 ko:K01756 1.0 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 1.0 M00048,M00049 1.0 R01083,R04559 1.0 RC00379,RC00444,RC00445 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADSL_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adenylosuccinate lyase. succino AMP-lyase. Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole. (1) N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate. (2) (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamide + fumarate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 320734 0 0 0 0 0 678341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 594145 0 0 0 0 0 848997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816555 0 0 0 0 0 1693335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317275 0 0 0 0 0 417502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260050 0 0 0 0 0 579993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHALFWADGEPNR MGYG000001378_02163;MGYG000002560_00851;MGYG000002478_02855;MGYG000000098_00878;MGYG000000196_04522;MGYG000002281_01893;MGYG000002549_02754;MGYG000000224_01028;MGYG000000105_02930;MGYG000000243_00155;MGYG000001313_02627;MGYG000002171_02204;MGYG000003681_01113;MGYG000001345_00470;MGYG000000013_01207 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG3630@1|root,COG3630@2|Bacteria,4NV8J@976|Bacteroidetes,2G2DV@200643|Bacteroidia,4AVXB@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 COG NOG19100 non supervised orthologous group 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 LTD,OAD_gamma 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 600962 268474 561915 483145 572347 0 0 660342 532646 0 480502 373567 502991 0 685116 599015 0 1947777 701737 0 670172 0 1364100 0 299424 619329 637564 3202432 0 632953 0 528386 645591 0 431274 910076 527137 753548 722784 447008 573637 829711 509244 0 0 787599 740534 0 639689 888855 590787 0 948360 368411 0 0 865358 0 714404 0 282492 0 507554 965692 714223 184414 0 790207 0 790543 602287 0 353139 495247 748418 695775 391489 454189 355418 788719 550069 0 0 310139 607527 0 448285 650929 584998 0 435878 426931 0 671857 355684 0 467268 0 270668 0 500399 527162 611079 471646 0 636015 0 0 353137 0 0 834939 425025 524332 0 345140 0 289640 417145 0 0 0 351765 0 0 450385 186639 0 0 263112 0 0 0 0 0 0 0 0 0 0 0 0 0 313260 0 345655 0 0 0 0 403269 280062 388043 432138 0 0 0 0 0 565358 606262 0 0 0 770555 0 0 660330 0 0 488865 0 0 0 496931 0 243941 273534 534757 0 0 318183 0 0 0 0 550505 0 362323 0 -(Gln->pyro-Glu)QHEVLYYGPQDEAEVK MGYG000000074_01490 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0612@1|root,COG0612@2|Bacteria,4NDXM@976|Bacteroidetes,2FNQC@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Belongs to the peptidase M16 family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M16C_assoc,Peptidase_M16,Peptidase_M16_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1197904 564015 0 739044 715358 418432 0 834663 1065276 651482 0 858688 458445 334328 301874 760147 825701 0 615652 747698 1346281 0 0 1586857 384530 616488 681499 0 0 677739 0 1102858 725380 0 736264 924353 613492 1735920 1463357 372164 943184 229945 783184 1991977 1148030 1282919 1036655 876784 0 834869 705507 1399948 493905 1363718 744127 0 1432320 569363 1070672 414236 0 761946 195885 381599 620508 0 0 0 0 1204250 732354 0 1876850 745754 503489 878119 322741 0 863271 631041 0 745388 536113 701349 844703 0 0 579390 1296150 0 350177 0 0 0 516540 479916 630232 797485 0 770503 241713 804894 314768 0 716937 637998 0 720642 570587 0 310500 370869 580667 1002892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319704 0 0 0 0 0 0 0 0 0 412566 0 0 543273 549492 685822 1112266 1706760 879820 855825 719478 371815 757723 0 598561 856699 685376 804273 697832 860889 0 1019160 1072440 466231 532402 0 702824 772323 1030435 656974 0 756753 739246 0 685606 621752 0 924574 943184 1254968 1042322 -(Gln->pyro-Glu)QHFLC(Carbamidomethyl)GTGTTAR MGYG000002517_01837 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 methylglyoxal synthase 1.0 mgsA 1.0 - 1.0 2.7.1.24,4.2.3.3 1.0 ko:K00859,ko:K01734 1.0 ko00640,ko00770,ko01100,ko01120,map00640,map00770,map01100,map01120 1.0 M00120 1.0 R00130,R01016 1.0 RC00002,RC00078,RC00424 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoaE,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 dephospho-CoA kinase. | methylglyoxal synthase. dephosphocoenzyme A kinase. Does not act on D-glyceraldehyde 3-phosphate.-!-Formerly EC 4.2.99.11. 3'-dephospho-CoA + ATP = ADP + CoA + H(+). | dihydroxyacetone phosphate = methylglyoxal + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Propanoate metabolism;Pantothenate and CoA biosynthesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 668875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 706506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468896 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHGGDLIFR MGYG000002478_01628 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,2FN2D@200643|Bacteroidia,4AKMG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) 1.0 gltX 1.0 - 1.0 6.1.1.17 1.0 ko:K01885 1.0 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 1.0 M00121,M00359,M00360 1.0 R05578 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 1.0 - 1.0 - 1.0 - 1.0 tRNA-synt_1c 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate--tRNA ligase. glutamyl-tRNA synthetase. - ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis;Metabolic pathways;Porphyrin metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1037872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHGIDLPFSADNSYSR MGYG000000179_03143 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,26889@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Arginosuccinate synthase 1.0 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Fluid shear stress and atherosclerosis;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1180777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHGTHIHPGENVGR MGYG000002919_00595;MGYG000003266_00534;MGYG000000188_00101;MGYG000001642_00797;MGYG000002947_00317 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4CW85@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL27 family 1.0 rpmA 1.0 - 1.0 - 1.0 ko:K02899 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHGYETVVMGASFR MGYG000002494_02911 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0176@1|root,COG0303@1|root,KOG2371@2759|Eukaryota,KOG2772@2759|Eukaryota,3AHVW@33154|Opisthokonta,3BZ72@33208|Metazoa,3DEMK@33213|Bilateria,40QWN@6231|Nematoda,1M0KR@119089|Chromadorea,4171K@6236|Rhabditida 1.0 2759|Eukaryota 1.0 G 1.0 Transaldolase/Fructose-6-phosphate aldolase 1.0 CNX1G 1.0 - 1.0 2.10.1.1,2.2.1.2,2.7.7.75 1.0 ko:K00616,ko:K13168,ko:K15376 1.0 ko00030,ko00790,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04727,map00030,map00790,map01100,map01110,map01120,map01130,map01200,map01230,map04727 1.0 M00004,M00007 1.0 R01827,R09726,R09735 1.0 RC00002,RC00439,RC00604,RC03462 1.0 ko00000,ko00001,ko00002,ko01000,ko03041 1.0 - 1.0 - 1.0 - 1.0 AIRS,DRY_EERY,DUF1244,MoCF_biosynth,MoeA_C,MoeA_N,PgpA,Proteasome,RecA,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 molybdopterin molybdotransferase. | transaldolase. | molybdopterin adenylyltransferase. glycerone transferase. Catalyzes the insertion of molybdenum into the ene-dithiol group of molybdopterin.-!-In eukaryotes this reaction is catalyzed by the N-terminal domain of a fusion protein whose C-terminal domain catalyzes EC 2.7.7.75. | Catalyzes the activation of molybdopterin for molybdenum insertion.-!-In eukaryotes, this reaction is catalyzed by the C-terminal domain of a fusion protein that also includes EC 2.10.1.1.-!-Formerly EC 2.7.7.n5. adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin. | D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | ATP + H(+) + molybdopterin = adenylyl-molybdopterin + diphosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;GABAergic synapse;Carbon metabolism;Metabolic pathways;Folate biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 1652601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 908566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 509520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2309273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHLGSEYR MGYG000000254_00984;MGYG000001552_00916;MGYG000003681_01837 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG3391@1|root,COG3391@2|Bacteria,4NJJN@976|Bacteroidetes,2FNI0@200643|Bacteroidia,22Z3Y@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 amine dehydrogenase activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 3015950 0 2767471 3910304 0 3920284 0 0 3329708 2865294 0 0 0 3470691 0 0 3578924 0 0 0 0 3218022 0 3868740 0 2948117 0 0 0 0 3272087 0 3511647 6342512 3035432 0 3146484 3366223 2438562 0 2750445 2955779 0 1789512 0 0 2902821 2616094 0 0 0 3043607 0 0 1966402 0 0 0 0 2073349 0 1854719 0 2560998 0 0 0 0 1457883 0 2928867 3260592 1874401 0 2465392 3122775 1715156 0 2919476 1733628 0 2894093 0 0 3040539 2065471 0 0 0 2281678 0 0 1981811 0 0 0 0 2276358 0 3425634 0 1552197 0 0 0 0 2699124 0 1866623 1833931 1948643 0 2202031 3025404 668527 0 693998 0 0 0 0 0 543112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 842827 0 0 0 0 0 0 0 1649551 1124575 0 705927 0 1800750 0 2146530 2455283 0 3434002 0 0 3072974 2047429 0 0 0 1244604 0 0 2179070 0 0 0 0 2407642 0 2380451 0 3103906 0 0 0 0 2236485 0 1245907 1456694 2693936 0 2627610 2412477 -(Gln->pyro-Glu)QHLVDIK MGYG000002560_01730;MGYG000001345_00428;MGYG000000042_02678;MGYG000002561_01024;MGYG000003693_00676;MGYG000000013_01171;MGYG000002549_02787;MGYG000001306_03824;MGYG000001337_03683;MGYG000004899_00334;MGYG000003470_01719;MGYG000000243_00095;MGYG000004479_01116;MGYG000000196_04414;MGYG000001789_02092;MGYG000004629_01597;MGYG000001461_03964;MGYG000000029_01835;MGYG000003681_00938;MGYG000001346_02526;MGYG000001489_04394;MGYG000001313_00862;MGYG000002478_04117;MGYG000003221_00209;MGYG000000236_00388;MGYG000001835_01025;MGYG000000415_01202;MGYG000004763_00186 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 0.8571428571428571 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 1395180 2025750 1714392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2154094 1942468 1680546 1778995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1947537 0 0 0 0 1902826 0 0 0 0 0 0 0 0 0 0 2048755 0 0 0 0 2863751 3739002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4472242 0 0 0 0 0 0 0 0 2436848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1500352 0 0 0 0 0 -(Gln->pyro-Glu)QHLVLNLVSSPGSGK MGYG000002535_00734;MGYG000002494_04480 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,3XNGB@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 KO 1.0 Required for the maturation of the three NiFe hydrogenases. Exhibits a low intrinsic GTPase activity. The GTP hydrolysis catalyzed by HypB is an integral process in the incorporation of nickel into hydrogenases 1.0 hypB 1.0 GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010467,GO:0016151,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:1901564 1.0 - 1.0 ko:K04652 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03110 1.0 - 1.0 - 1.0 - 1.0 cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1190350 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHNDANVLVLPGR MGYG000002293_00079;MGYG000003697_02026 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,2FT1X@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Ribose 5-phosphate isomerase 1.0 rpiB 1.0 - 1.0 5.3.1.6 1.0 ko:K01808 1.0 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01056,R09030 1.0 RC00376,RC00434 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 LacAB_rpiB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-5-phosphate isomerase. ribose phosphate isomerase. Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate. aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 796515 0 0 612177 0 736931 0 0 815740 0 0 766040 0 0 0 0 0 1301489 0 0 0 881590 1969091 601993 722974 641376 0 1036631 0 0 0 0 0 709840 0 0 768876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244173 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHNITAMNANR MGYG000000398_01963 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__TF01-11|s__|m__MGYG000000398 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 777419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHNLTAM(Oxidation)NANR MGYG000000398_01070;MGYG000000997_01685;MGYG000002580_01396;MGYG000000076_03207;MGYG000002552_01183;MGYG000000562_01318;MGYG000000398_01963;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 301233 0 0 471123 0 0 0 0 0 676008 0 0 0 573560 512394 618112 782118 0 0 0 0 0 0 0 0 221342 0 0 0 0 0 0 0 0 0 363256 405975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317657 0 0 546451 0 0 0 0 0 465282 0 0 0 588007 943486 259826 270866 0 0 0 0 0 0 0 0 802998 0 0 0 0 0 0 0 0 0 434263 1099507 0 425183 0 0 0 0 0 0 0 0 618343 0 0 1351001 166158 627582 342853 299916 0 0 0 0 0 0 0 0 421651 0 0 0 0 0 0 0 0 0 0 197229 0 -(Gln->pyro-Glu)QHNLTAMNANR MGYG000000398_01070;MGYG000000997_01685;MGYG000002580_01396;MGYG000000076_03207;MGYG000002552_01183;MGYG000000562_01318;MGYG000000398_01963;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 2610240 1398708 1150679 4159858 1895908 1776447 1945702 2355048 2813802 3046116 2153875 2949671 2536575 3321334 2661926 1675951 3000670 0 2560001 1423056 2640168 1330687 0 2033190 2174119 2604546 2612060 0 824058 3099599 1261067 1267761 1677335 2649182 2372627 2220027 3136359 1166403 0 0 0 0 0 0 0 0 0 0 0 262525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219256 661570 0 0 506617 0 336861 483717 930724 594787 831604 379202 736252 0 510070 658229 469342 270362 0 570602 629059 0 0 0 0 928764 872995 744561 0 0 822577 213739 0 0 547332 906612 614739 881183 0 1964130 490837 861214 1895311 1298451 980117 1355134 2921690 3077653 1498564 1164416 1758262 1635913 2669719 3883726 1125193 1560715 0 2299877 1580735 2113415 0 0 509722 3783731 3729241 2382986 0 536256 2394200 738697 1028279 731804 4148206 3184582 2410384 4087928 514040 4474022 3102667 2652274 559575 2751734 3127366 1210393 2290806 2424730 6576561 3108470 2003929 6773032 2658380 5606184 2513285 3232513 0 4906001 2519456 2768728 2698369 0 2659294 3819815 3576662 4232609 0 1136131 3276986 2351699 2620683 3801046 4185784 4994764 3643135 4129317 2410546 -(Gln->pyro-Glu)QHNMQAANANR MGYG000002670_01665;MGYG000002670_01663;MGYG000002492_03078;MGYG000001141_00820 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.75 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407702 0 573176 0 0 0 0 0 651152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466133 0 0 0 0 488811 0 0 275167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310244 0 0 0 0 216434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHNVEGTVYDDAAK MGYG000003686_01440 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4|s__ER4 sp000765235|m__MGYG000003686 1.0 COG1404@1|root,COG1404@2|Bacteria,1UM3J@1239|Firmicutes 1.0 1239|Firmicutes 1.0 O 1.0 S-layer homology domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2110602 0 0 0 0 1945563 0 0 0 0 2177718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHPSFK MGYG000001789_01676 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002161565|m__MGYG000001789 1.0 COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,2FSHU@200643|Bacteroidia,4AQXS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 706800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1296034 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 684744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 925422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1161852 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHTPGYDPNAK MGYG000002293_02142;MGYG000002960_01872;MGYG000003697_01320 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,2FP7M@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the pseudouridine synthase RsuA family 1.0 rluB 1.0 - 1.0 5.4.99.22 1.0 ko:K06178 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03009 1.0 - 1.0 - 1.0 - 1.0 PseudoU_synth_2,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 23S rRNA pseudouridine(2605) synthase. - Pseudouridine synthase RluB converts uridine(2605) of 23S rRNA to pseudouridine. uridine(2605) in 23S rRNA = pseudouridine(2605) in 23S rRNA. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599269 0 0 0 0 0 0 0 988339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 863491 0 0 0 0 963982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHTSFVVR MGYG000000074_00430 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 28X6E@1|root,2ZJ4T@2|Bacteria,4P99Y@976|Bacteroidetes,2FZDY@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 927813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHVIYK MGYG000002494_02289;MGYG000002323_04134;MGYG000002506_03286 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,3X2KI@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL28 family 1.0 rpmB 1.0 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02902 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2019997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2216022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHVLYK MGYG000002535_04391;MGYG000002477_00502;MGYG000002534_00101;MGYG000002494_02289;MGYG000003372_03385;MGYG000002515_03800;MGYG000002323_04134;MGYG000002506_03286;MGYG000002476_00305;MGYG000002504_04504 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,3X2KI@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL28 family 1.0 rpmB 1.0 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02902 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2490818 0 0 0 2338015 0 0 0 0 970125 0 0 0 0 0 1801264 2638258 0 0 1879424 0 0 0 2488304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187634 0 0 0 0 0 0 0 0 429941 0 0 0 0 0 0 0 0 0 0 0 0 0 95948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325227 0 0 0 0 416918 0 0 0 0 0 193575 0 0 0 73759 0 0 0 121472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QHVPVFVTDEMVGHK MGYG000001708_01470;MGYG000002534_00396;MGYG000002507_04185;MGYG000000235_04536;MGYG000002494_02465;MGYG000002477_00183;MGYG000002323_00390;MGYG000002500_04421;MGYG000002504_03960;MGYG000002506_02957;MGYG000002515_03199 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA 1.0 rpsS 1.0 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02965 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 466352 427577 293085 323314 162563 662019 557590 726677 608229 680292 0 0 0 647083 542921 0 150447 0 324094 498170 628128 577869 0 580248 636282 0 283429 0 166637 0 452902 0 374276 358611 651211 590587 257590 170532 823003 825256 1105128 957869 1234502 2359812 1054646 980298 708227 1697269 0 0 0 1062091 891732 0 1185097 0 1481178 935501 1134489 2153823 0 1611226 1141263 892673 1143704 0 1521733 964709 411899 0 909373 844460 857814 765834 732406 731729 175760 0 237245 0 359889 622821 0 0 0 174117 0 0 0 213632 352424 0 0 0 0 184578 249349 482364 0 443247 265573 0 357409 0 418393 157241 0 0 206383 400191 359783 411072 0 0 301753 204987 176752 78008 390482 579802 327760 202927 241651 797455 0 0 0 0 194558 0 192507 0 215985 275490 175205 603883 0 585979 212037 0 0 0 0 537751 199729 0 339737 337093 388036 162720 346778 385260 0 0 0 0 265231 0 0 0 0 0 0 0 0 197133 0 0 0 0 0 0 0 171301 0 161442 328548 0 89505 0 0 0 0 0 0 0 0 0 220241 0 -(Gln->pyro-Glu)QIADKYGVPHISTGDIFR MGYG000000271_01082 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism 1.0 adk 1.0 - 1.0 2.7.4.3 1.0 ko:K00939 1.0 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 1.0 M00049 1.0 R00127,R01547,R11319 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS20110 1.0 ADK,ADK_lid 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adenylate kinase. myokinase. Inorganic triphosphate can also act as donor. AMP + ATP = 2 ADP. 1.0 1.0 1.0 1.0 Thiamine metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIADKYSIPHISTGDIFR MGYG000002517_02852 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism 1.0 adk 1.0 - 1.0 2.7.4.3 1.0 ko:K00939 1.0 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 1.0 M00049 1.0 R00127,R01547,R11319 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS20110 1.0 ADK,ADK_lid 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adenylate kinase. myokinase. Inorganic triphosphate can also act as donor. AMP + ATP = 2 ADP. 1.0 1.0 1.0 1.0 Thiamine metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 1211487 0 0 0 0 0 0 0 1577809 0 0 0 0 0 0 0 1058995 0 896795 493607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 616969 0 0 0 0 0 0 0 510986 0 0 0 0 0 0 0 738221 0 580401 806923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 619560 0 0 0 0 0 0 0 563966 0 0 0 0 0 0 0 684401 0 468073 897540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234833 0 0 0 0 0 0 0 459250 0 0 0 0 0 0 0 309530 0 680137 440548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1398127 0 0 0 0 0 0 0 2164352 0 0 0 0 0 0 0 0 0 44951 2370153 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIASNAGMEGAIVAEKVK MGYG000004158_00394 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister invisus|m__MGYG000004158 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4H29X@909932|Negativicutes 1.0 909932|Negativicutes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 - 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIC(Carbamidomethyl)DIGRR MGYG000000200_00392;MGYG000001338_00134;MGYG000000252_02294;MGYG000000133_00165;MGYG000002966_00348;MGYG000002298_02773;MGYG000004733_01681;MGYG000000171_01273;MGYG000000212_01008;MGYG000002298_00038;MGYG000000301_01359 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3WHFE@541000|Ruminococcaceae 0.5454545454545454 186801|Clostridia 1.0 G 1.0 L-fuculose phosphate aldolase 0.5454545454545454 fucA 0.5454545454545454 - 1.0 4.1.2.17 1.0 ko:K01628 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R02262 1.0 RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fuculose-phosphate aldolase. L-fuculose-1-phosphate lactaldehyde-lyase. - L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 946489 0 0 0 175486 0 521123 0 1058106 0 0 0 0 1220736 0 0 826155 0 0 0 0 0 0 0 0 0 0 0 0 0 862896 496983 0 0 0 950930 0 0 0 0 0 0 409916 0 550137 0 388921 0 0 0 0 130974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374836 305616 0 0 0 382549 0 0 1266958 0 0 0 826930 0 932513 0 820139 0 0 0 0 1054756 0 0 1394263 0 0 0 0 0 0 0 0 0 0 0 0 0 1451669 1598253 0 0 0 998222 0 0 502757 0 0 0 0 0 635032 0 372417 0 0 0 0 541186 0 0 339674 0 0 0 0 0 0 0 0 0 0 0 0 0 475655 0 0 0 0 522691 0 0 2082464 0 0 0 2326850 0 1871333 0 2621540 0 0 0 0 1580827 0 0 2271059 0 0 0 0 0 0 0 0 0 0 0 0 0 3108591 2602347 0 0 0 1796407 -(Gln->pyro-Glu)QIDKNEAR MGYG000002619_02370;MGYG000002274_00828;MGYG000002610_01878;MGYG000002040_00986;MGYG000000195_02117;MGYG000000022_02024;MGYG000002641_00972;MGYG000002651_00731 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3WJ8R@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 729945 683125 973593 914376 0 218624 485449 362424 660642 0 0 0 0 936985 0 0 304363 181261 718596 380891 0 616153 802426 668666 497615 701794 523682 1264530 0 213238 0 304665 1257979 1289916 0 0 651177 692675 1698018 1747496 2087486 2231916 0 1878629 2639213 976120 2317806 0 0 0 0 2908673 2527768 0 2784795 1780166 3098255 2191973 1187140 1434594 3298156 1464415 3343746 2340903 2730074 2867663 0 1959811 0 1717168 2617632 2425535 0 0 1472969 2011509 0 0 0 0 0 0 188519 0 0 0 0 0 0 0 0 0 0 1954799 0 0 152726 0 1539904 0 0 0 0 1317937 0 0 0 0 0 0 0 0 0 0 541659 599952 1556729 726965 0 1013951 924109 415293 882389 0 0 0 0 827692 1176016 0 512093 747536 1277760 797313 536438 1039663 920139 649969 1427277 959071 771511 687640 0 1248104 0 877886 1261043 1998276 0 0 1150725 1072262 0 0 0 148926 0 0 0 0 0 0 0 0 0 0 0 0 0 1810060 0 0 0 0 1401468 0 0 0 0 1885743 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIEDNKDALK MGYG000000223_00973 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG2222@1|root,COG2222@2|Bacteria,1TQUT@1239|Firmicutes,3VP6T@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 M 1.0 Sugar isomerase, AgaS family 1.0 - 1.0 - 1.0 - 1.0 ko:K02082 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 SIS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 703929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 983175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIEEEIVEVGKR MGYG000003542_01378;MGYG000003469_00458;MGYG000000053_00926;MGYG000002082_01733;MGYG000000074_01808 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia,22U4P@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Endoribonuclease that initiates mRNA decay 1.0 rny 1.0 - 1.0 - 1.0 ko:K18682 1.0 ko03018,map03018 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03019 1.0 - 1.0 - 1.0 - 1.0 DUF3552,HD,KH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIEEQSDKLIR MGYG000002279_01084;MGYG000002992_00601;MGYG000000038_01565 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24AN3@186801|Clostridia,27WHN@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 RnfC Barrel sandwich hybrid domain 1.0 prdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,RnfC_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIEETTSDFDREK MGYG000000919_03652;MGYG000000202_00541;MGYG000002992_01078;MGYG000000038_02089;MGYG000003486_00745;MGYG000001607_00737;MGYG000001496_00484;MGYG000000278_02028;MGYG000000179_05119;MGYG000001615_01161;MGYG000000198_00464;MGYG000002445_00865;MGYG000000217_01904;MGYG000003783_01372;MGYG000001367_02937;MGYG000001688_01574;MGYG000001617_04641;MGYG000004087_02347;MGYG000000262_01443;MGYG000001193_01063;MGYG000002247_01828;MGYG000002279_00394 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,21YIV@1506553|Lachnoclostridium 0.4090909090909091 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.9545454545454546 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 804839 0 0 779264 0 0 264381 0 410229 427367 0 478942 358930 893964 739502 0 796262 877000 512861 844137 816073 0 514864 0 0 563320 391159 768228 0 894804 0 0 0 270954 0 986150 264131 0 0 0 0 347227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217053 0 0 0 0 0 0 0 0 0 0 0 1213642 0 739584 1489351 0 0 1078218 0 921032 829862 0 991904 650315 1199459 1442548 0 846791 0 917033 1096099 1355289 0 0 0 0 1100431 1253671 396761 0 1211338 0 0 852599 1282828 0 984193 1042206 629429 602695 0 320157 477650 0 0 445963 0 508143 508684 0 291439 312927 181340 0 0 536345 0 313045 478823 580304 0 0 0 0 341714 780376 0 0 427003 0 0 337570 734236 0 700670 466904 509681 1521269 0 876445 861116 0 0 1681932 0 1651923 1615350 0 786955 445075 1112226 1746475 0 1349353 0 1424196 1518241 1236383 0 0 0 0 1545045 1496793 540341 0 923470 0 0 1066680 2405864 0 994374 1661974 1019564 -(Gln->pyro-Glu)QIGGGLVTAMVR MGYG000002494_04005;MGYG000003372_01152;MGYG000002477_02044;MGYG000002534_03547 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG4576@1|root,COG4577@1|root,COG4576@2|Bacteria,COG4577@2|Bacteria,1RIK4@1224|Proteobacteria,1S6GW@1236|Gammaproteobacteria,3ZNAY@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 CQ 1.0 Ethanolamine utilisation protein EutN/carboxysome 1.0 eutN 1.0 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 1.0 - 1.0 ko:K04028 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC,EutN_CcmL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426245 494555 629856 674343 0 567987 637648 684558 443940 948749 337806 650693 0 591932 647838 0 600794 0 635165 503519 622109 588249 0 487190 610626 565209 665392 0 0 863100 0 588250 574996 610225 0 0 518865 364147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 43348 0 0 0 73536 0 0 0 0 0 0 0 0 0 0 0 115927 0 143846 125225 0 0 0 0 0 0 0 41744 0 0 0 0 0 0 0 0 339635 0 560336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136164 0 0 0 46323 0 0 0 0 0 0 0 0 0 0 0 493302 -(Gln->pyro-Glu)QIGPSNIAAGESDEVK MGYG000002517_02160 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2182@1|root,COG2182@2|Bacteria,1VRPK@1239|Firmicutes,24Y63@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 210373 495711 405181 500378 0 603786 355315 0 575629 902697 449040 473250 0 407671 225991 517413 456402 0 435315 248619 0 400951 0 656175 444247 460429 700229 0 0 0 410139 0 435235 584653 675012 750561 616743 438104 0 444905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 528834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209909 0 0 0 0 394312 662659 600427 406230 0 352980 775526 0 575533 425211 408454 555884 0 371872 398293 0 433154 0 433372 459118 0 417164 0 349410 640511 427397 478735 0 0 0 779137 0 376360 717168 304427 586792 260376 461664 718719 199339 621555 839827 0 330200 504059 0 874052 336732 498146 536595 0 1274719 913604 641681 745821 0 886187 791974 0 350677 0 299479 799734 871548 743501 0 0 0 385909 0 0 0 1103219 858490 894318 400087 1195007 1001477 1863090 1119376 0 1516970 1671450 0 1722053 1301901 1354345 1466790 0 1068049 1675449 1098374 1474395 0 1322101 1091240 0 826722 0 1737480 2166843 1908892 1538003 0 0 0 1299785 0 1869397 2202839 1274889 1064228 2092310 0 -(Gln->pyro-Glu)QIGQTGVTVHPK MGYG000002960_00220;MGYG000003697_02505;MGYG000002603_00030;MGYG000002293_02659;MGYG000001306_03030 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia 0.8 976|Bacteroidetes 1.0 C 1.0 Electron transfer flavoprotein 0.8 etfA 1.0 - 1.0 - 1.0 ko:K03522 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha 0.8 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 625494 0 0 0 0 852843 0 0 0 0 704175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1408692 0 0 1302204 0 0 0 0 0 0 0 0 0 0 0 1612301 0 0 0 1308544 1524881 957620 0 0 0 1597748 0 0 0 0 1174025 0 0 0 0 1247112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278009 0 0 0 0 269557 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIGQTGVTVRPK MGYG000000013_01113;MGYG000004830_00491;MGYG000002181_01061;MGYG000004464_00650;MGYG000002281_01803;MGYG000001346_02512;MGYG000003469_01112;MGYG000003554_01591;MGYG000000224_01764;MGYG000004885_01161;MGYG000001370_00111;MGYG000001313_00856;MGYG000003420_00108;MGYG000003521_01088;MGYG000001661_01629;MGYG000002549_02818;MGYG000000673_00584;MGYG000001659_01714;MGYG000003922_03089;MGYG000000196_04139;MGYG000004876_02153;MGYG000001378_04598;MGYG000000138_01469;MGYG000000825_02222;MGYG000003221_01664;MGYG000002033_00723;MGYG000003926_00355;MGYG000004720_00561;MGYG000001489_04895;MGYG000003367_00837;MGYG000002721_00910;MGYG000000029_01804;MGYG000004824_01248;MGYG000000243_00604;MGYG000003498_00874;MGYG000000054_02441;MGYG000001503_00716;MGYG000002275_00940;MGYG000001666_00851;MGYG000004638_00871;MGYG000004748_00350;MGYG000002218_00406;MGYG000003460_00807;MGYG000001345_00397;MGYG000003535_01795;MGYG000003952_01067;MGYG000000098_00812;MGYG000001337_03725;MGYG000002560_03243;MGYG000000105_03056;MGYG000003542_01687;MGYG000000354_00401;MGYG000001630_00164;MGYG000001429_00436;MGYG000002478_00354;MGYG000003423_01173;MGYG000002438_02892;MGYG000003681_02880;MGYG000001643_03097;MGYG000000044_02111 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia,4AKN9@815|Bacteroidaceae 0.45 976|Bacteroidetes 0.9833333333333333 C 1.0 Psort location Cytoplasmic, score 8.96 0.45 etfA 0.8833333333333333 - 1.0 - 0.9833333333333333 ko:K03522 0.8666666666666667 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko04147 0.8666666666666667 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha 0.8166666666666667 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9833333333333333 0.9833333333333333 0.9833333333333333 0.9833333333333333 1.0 none 1.0 1394681 1605797 1519758 1320820 1773580 1217603 1564763 1306319 1177703 1180488 1442838 1409251 1445792 1494551 1500403 2051772 1579453 884883 1235914 1418978 1420623 1201121 979166 1826433 1231390 1523994 1535990 959494 1217765 1285945 1412319 1551571 2074396 1565556 1583253 1413741 1399887 1590465 1511002 1025949 1527510 1721983 1571389 1324175 1081629 1570236 1477678 1496799 1708079 1781297 1267666 1397831 1268502 1262193 1210552 496751 1491294 1052403 1347605 1218132 723100 845546 1320465 1403097 1388265 884805 1184914 1530792 814998 1229212 1107335 1247739 1532003 1225405 1722015 1348668 886674 914663 1282174 903275 1464032 1253481 1108460 873418 1034801 844025 1483721 1011476 1238423 985491 933682 1279933 989823 1530541 1104018 973631 980400 1113390 1658229 1069842 1070809 874404 843513 1470768 1103618 1401950 1341572 880326 987717 806703 1145149 981590 986953 937277 834963 1049334 996672 782790 814804 779647 850877 929172 934371 930739 919909 1215991 1079927 875446 804948 936029 775429 732767 808183 686118 1176221 823606 633545 646157 1059313 1220687 717399 577852 846682 971844 785987 1105549 980287 1088809 1522299 1190950 1112224 763696 864565 910678 933360 1265677 1298719 1440786 1188194 1268190 1424243 917230 1271238 1367515 1176117 885849 978299 1561626 1183027 1462239 1185474 1152686 1211454 1107863 1524984 1110399 1075699 1165857 894341 1098675 930448 2260156 1023453 1327284 582572 1333232 1357296 810648 1423139 1010083 -(Gln->pyro-Glu)QIGVTLPHLK MGYG000002478_00678;MGYG000004797_01301;MGYG000000243_02708 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0235@1|root,COG0235@2|Bacteria,4NIQK@976|Bacteroidetes,2FN5U@200643|Bacteroidia,4AN95@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases 1.0 rhaD 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 1.0 4.1.2.19 1.0 ko:K01629 1.0 ko00040,ko00051,ko01120,map00040,map00051,map01120 1.0 - 1.0 R01785,R02263 1.0 RC00438,RC00599,RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 rhamnulose-1-phosphate aldolase. L-rhamnulose-phosphate aldolase. - L-rhamnulose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions;Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644417 0 0 0 0 427928 0 0 0 0 410091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 129376 0 0 0 0 104147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 824224 0 0 0 0 920032 0 0 0 0 732687 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIGYQPYEDEGKIK MGYG000000133_00899 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1879@1|root,COG1879@2|Bacteria,1TSUI@1239|Firmicutes,24BR7@186801|Clostridia,26BK5@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K02058 1.0 - 1.0 M00221 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1.2 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1724427 0 0 0 1471286 0 0 0 0 1514689 0 0 2810567 0 0 0 2990726 0 0 0 0 0 0 0 0 0 0 0 0 1650883 2128069 0 0 0 0 1436432 -(Gln->pyro-Glu)QIIAEVDAIC(Carbamidomethyl)R MGYG000001338_01864;MGYG000000216_03383;MGYG000000184_02632;MGYG000000142_01112;MGYG000004296_00030;MGYG000002025_00748;MGYG000000200_00055;MGYG000003821_00296;MGYG000003012_02009 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,3Y0ZT@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 4Fe-4S dicluster domain 1.0 - 1.0 - 1.0 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.0 ko:K03388 1.0 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 1.0 M00356,M00357,M00563,M00567 1.0 R04540,R11928,R11931,R11943,R11944 1.0 RC00011 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Fer4,Fer4_10,Fer4_7,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ferredoxin:CoB-CoM heterodisulfide reductase. | coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase. | H2:CoB-CoM heterodisulfide,ferredoxin reductase. | formate:CoB-CoM heterodisulfide,ferredoxin reductase. - HdrABC is an enzyme complex that is found in most methanogens and catalyzes the reduction of the CoB-CoM heterodisulfide back to CoB and CoM.-!-HdrA contains a FAD cofactor that acts as the entry point for electrons, which are transferred via HdrC to the HdrB catalytic subunit.-!-One form of the enzyme from Methanosarcina acetivorans (HdrA2B2C2) can also catalyze EC 1.8.98.4. cf. EC 1.8.98.5, EC 1.8.98.6, and EC 1.8.98.1. | The enzyme, characterized from the archaeon Methanosarcina acetivorans, catalyzes the reduction of CoB-CoM heterodisulfide back to CoB and CoM.-!-The enzyme consists of three components, HdrA, HdrB and HdrC, all of which contain [4Fe-4S] clusters.-!-Electrons enter at HdrA, which also contains FAD, and are transferred via HdrC to the catalytic component, HdrB.-!-During methanogenesis from acetate the enzyme catalyzes the activity of EC 1.8.7.3.-!-However, it can also use electron bifurcation to direct electron pairs from reduced coenzyme F420 toward the reduction of both ferredoxin and CoB-CoM heterodisulfide.-!-This activity is proposed to take place during Fe(III)-dependent anaerobic methane oxidation. cf. EC 1.8.98.5, EC 1.8.98.6, and EC 1.8.98.1. | This enzyme complex is found in H2-oxidizing CO2-reducing methanogenic archaea such as Methanothermobacter thermautotrophicus.-!-It consists of a cytoplasmic complex of HdrABC reductase and MvhAGD hydrogenase.-!-Electron pairs donated by the hydrogenase are transferred via its Delta subunit to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide.-!-The reductase can also form a similar complex with formate dehydrogenase, see EC 1.8.98.6, formate:CoB-CoM heterodisulfide,ferredoxin reductase. cf. EC 1.8.7.3, EC 1.8.98.4, and EC 1.8.98.1. | The enzyme is found in formate-oxidizing CO2-reducing methanogenic archaea such as Methanococcus maripaludis.-!-It consists of a cytoplasmic complex of HdrABC reductase and formate dehydrogenase.-!-Electron pairs donated by formate dehydrogenase are transferred to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide. cf. EC 1.8.7.3, EC 1.8.98.4, EC 1.8.98.5, and EC 1.8.98.1. coenzyme B + coenzyme M + 2 oxidized [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | coenzyme B + coenzyme M + 4 H(+) + 2 oxidized coenzyme F420-(gamma-L- Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 reduced coenzyme F420-(gamma-L-Glu)(n). | coenzyme B + coenzyme M + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H2 + 2 oxidized [2Fe-2S]- [ferredoxin]. | 2 CO2 + coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]- [ferredoxin]. 1.0 1.0 1.0 1.0 Metabolic pathways;Methane metabolism;Carbon metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIIEADIPMSGLFGYC(Carbamidomethyl)TDLR MGYG000002247_02135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Acetatifactor|s__Acetatifactor sp900771995|m__MGYG000002247 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,27JEC@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Elongation factor G, domain IV 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 847962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIIGVIDR MGYG000002494_04127 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3WV6W@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 K 1.0 Transcriptional regulator PadR-like family 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1470348 0 0 730403 1155973 0 0 0 0 770599 0 1123828 0 0 0 858220 1244946 0 890439 868354 0 0 0 0 0 0 0 0 569196 506100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIKDFSLGGFAR MGYG000002478_00657;MGYG000002560_00458 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKGC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02014 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 720995 0 0 0 0 0 0 0 792474 0 0 797320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287339 0 0 0 0 0 0 0 319508 0 0 365513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 130630 0 0 0 0 0 0 0 178926 0 0 259823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 872093 0 0 0 0 0 0 0 527497 0 0 875445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167917 0 0 0 0 0 0 0 143504 0 0 476965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIKEAVAAKK MGYG000001315_01866 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,27IGM@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIKYPLAAK MGYG000000133_00306;MGYG000001338_00214;MGYG000000142_02314;MGYG000000212_00040;MGYG000000002_02500;MGYG000000146_01483 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia 0.8333333333333334 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 324453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 494006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1606854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIKYPLAAKDEQGR MGYG000000133_00306;MGYG000001338_00214;MGYG000000171_02641 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 96809 0 0 0 0 0 100763 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 712117 824048 0 0 0 228409 0 0 519348 0 0 639807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704351 0 468543 0 1182882 0 0 0 0 495358 -(Gln->pyro-Glu)QIKYPLSAK MGYG000000271_00603;MGYG000002963_04223;MGYG000000204_01913;MGYG000004740_01385;MGYG000001637_01052;MGYG000000356_01714;MGYG000001319_00739;MGYG000002670_00089;MGYG000002836_02134;MGYG000001219_01350;MGYG000002992_01076;MGYG000000198_00495;MGYG000000193_00312;MGYG000003695_02134;MGYG000004869_03402;MGYG000004879_00512;MGYG000000164_00891;MGYG000004271_01872;MGYG000004087_02343;MGYG000001315_00701;MGYG000002517_01047;MGYG000001645_00506;MGYG000002492_02315;MGYG000002279_00396 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia 0.2916666666666667 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 1809818 2081379 0 0 0 0 0 0 0 0 0 0 0 0 0 2245971 2008915 0 0 0 0 2027322 0 0 0 0 2311787 0 0 0 0 1965739 0 0 0 0 1810816 0 439244 446942 0 0 0 0 0 0 0 0 0 0 0 0 0 582524 712026 0 0 0 0 496607 0 0 0 0 763808 0 0 0 0 739797 0 0 0 0 644953 0 1618939 1620421 0 0 0 0 0 0 0 0 0 0 0 0 0 1049410 1303470 0 0 0 0 1539845 0 0 0 0 1504772 0 0 0 0 1577822 0 0 0 0 1393754 0 880600 926598 0 0 0 0 0 0 0 0 0 0 0 0 0 929249 1232878 0 0 0 0 870041 0 0 0 0 1432282 0 0 0 0 940879 0 0 0 0 1092603 0 455515 977462 0 0 0 0 0 0 0 0 0 0 0 0 0 681553 1033797 0 0 0 0 0 0 0 0 0 1386297 0 0 0 0 918787 0 0 0 0 883792 -(Gln->pyro-Glu)QILEIISQNAR MGYG000001461_00185;MGYG000002933_01451;MGYG000000029_02715;MGYG000002549_03412;MGYG000000781_00112;MGYG000001789_02087;MGYG000001661_01271;MGYG000003221_02267;MGYG000004899_00478;MGYG000002455_01329;MGYG000001345_04455;MGYG000003922_01960;MGYG000002478_01011;MGYG000002281_04321;MGYG000003693_00243;MGYG000000054_02904;MGYG000002470_01569;MGYG000001337_04159;MGYG000004185_02372;MGYG000001750_00997;MGYG000001925_01762;MGYG000003312_01840;MGYG000002560_03655;MGYG000001364_02711;MGYG000001787_00015;MGYG000003351_03113;MGYG000004019_02623;MGYG000001780_02391;MGYG000004748_01119;MGYG000001599_01405;MGYG000000098_00470;MGYG000001783_01941;MGYG000002935_00927;MGYG000002171_00554;MGYG000000236_04556;MGYG000004797_01237;MGYG000003681_02173;MGYG000004876_01322;MGYG000002561_00327;MGYG000004479_02768;MGYG000000224_00608;MGYG000000105_01860;MGYG000001313_00277;MGYG000001346_02074;MGYG000000273_00327;MGYG000000043_02680;MGYG000001370_01791;MGYG000003252_03222;MGYG000000243_03093;MGYG000002291_02066;MGYG000001378_00204;MGYG000001306_02191;MGYG000000196_04706;MGYG000000013_02428 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,2FMP2@200643|Bacteroidia,4AM91@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 Transcriptional regulator, AsnC family 1.0 asnC 1.0 - 1.0 - 1.0 ko:K03718 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 AsnC_trans_reg,HTH_24,HTH_AsnC-type 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5301552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QILGTHVAQK MGYG000002494_04513 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,3ZKEI@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550876 0 462494 0 0 0 0 517796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QILLDTYYGR MGYG000002323_02346;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 1.0 adhE 1.0 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 112883 0 0 182669 0 0 0 69669 0 97877 0 0 0 0 0 0 0 79370 0 402744 0 223983 0 0 0 0 0 104763 0 113603 0 0 0 0 0 0 2069867 3508958 4138185 2565020 3429364 4644980 3849559 1682086 2678387 3442205 0 2032396 1482866 2856668 2436013 1982176 3402340 0 4012515 2379287 2842027 3683807 0 3636576 3295433 2297737 2509045 0 4523849 3630209 1126311 1707195 3176991 2176219 1884960 1807435 2374109 2301858 0 211421 0 0 96456 323366 76872 131163 108741 77064 0 174539 65992 73279 204638 172103 64772 0 111778 52072 0 371510 0 758856 153019 305528 114663 0 104043 0 322178 73580 89378 137923 0 223998 202175 147203 0 1365446 132684 0 0 0 590020 0 0 0 0 0 1215668 0 1283083 0 0 0 0 0 0 61669 0 0 0 0 0 0 99555 0 0 2838254 0 0 0 0 0 0 0 85874 0 0 0 177518 0 0 2050537 0 0 0 0 0 0 0 0 0 4760 0 0 0 0 0 0 0 5218 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QILLDTYYGRDYVEGETAAKK MGYG000002506_00529 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 1.0 adhE 1.0 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 402438 0 0 988242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 953297 0 716167 0 0 0 0 0 0 0 0 366310 0 0 0 0 344833 0 0 0 0 0 280209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 129658 0 0 203102 0 0 1336536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692206 0 690019 0 0 0 0 0 0 0 0 426635 0 0 0 0 430756 0 0 453588 0 0 554911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762613 0 424571 0 0 0 0 0 0 0 0 480033 0 0 0 0 152459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QILSGIK MGYG000001617_01701;MGYG000000198_00821 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,21Z1B@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 J 1.0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation 1.0 metG 1.0 - 1.0 6.1.1.10 1.0 ko:K01874 1.0 ko00450,ko00970,map00450,map00970 1.0 M00359,M00360 1.0 R03659,R04773 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,tRNA-synt_1g,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 GH84 1.0 methionine--tRNA ligase. MetRS. In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9. ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis;Selenocompound metabolism 1.0 none 1.0 0 0 0 0 0 528074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 560352 0 452534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 198346 0 289370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1292716 0 438058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2925971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1597129 0 1657263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362044 0 495512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QILVQENDYVR MGYG000003312_01247;MGYG000001306_02654;MGYG000000183_03082;MGYG000002560_00228;MGYG000002935_00902;MGYG000003693_02792;MGYG000002455_03893;MGYG000001378_05033;MGYG000000243_01979;MGYG000001346_01525;MGYG000000105_01994;MGYG000001313_00088;MGYG000000224_00483;MGYG000000442_01373;MGYG000001345_04693;MGYG000000400_00966;MGYG000004757_00585;MGYG000004885_00605;MGYG000001920_01196;MGYG000000170_00064;MGYG000000196_03983;MGYG000004720_01708;MGYG000002549_02931;MGYG000002478_00805;MGYG000000042_01430;MGYG000001789_00145;MGYG000003351_04372;MGYG000004797_04274;MGYG000000054_03942;MGYG000002762_01078;MGYG000004105_01519;MGYG000001608_02201;MGYG000000236_01798;MGYG000004763_01698;MGYG000002291_02263;MGYG000003681_02045;MGYG000002556_01323 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 0.7297297297297297 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 0.972972972972973 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 8056448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1636637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIMTEIINSHSDMEM(Oxidation)VATAPDPLVAR MGYG000002506_01275;MGYG000002494_03454 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,3XNVQ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 NT 1.0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR 1.0 cheB 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006482,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0008214,GO:0008984,GO:0009605,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0018277,GO:0019538,GO:0019899,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051723,GO:0052689,GO:0070988,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1990827 1.0 3.1.1.61,3.5.1.44 1.0 ko:K03412 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheB_methylest,Response_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 protein-glutamate methylesterase. | protein-glutamine glutaminase. protein methyl-esterase. | peptidoglutaminase II. Hydrolyzes the products of EC 2.1.1.77, EC 2.1.1.78, EC 2.1.1.80 and EC 2.1.1.100. | Specific for the hydrolysis of the gamma-amide of glutamine substituted at the carboxyl position or both the alpha-amino and carboxyl positions, e.g., L-glutaminylglycine and L-phenylalanyl-L- glutaminylglycine. [protein]-L-glutamate 5-O-methyl ester + H2O = H(+) + L-glutamyl- [protein] + methanol. | H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+). 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QINAAESR MGYG000001313_01931;MGYG000002455_02656;MGYG000001346_03599;MGYG000003681_00353 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4372@1|root,COG4372@2|Bacteria,4NJGZ@976|Bacteroidetes,2G2H0@200643|Bacteroidia,4AKNU@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 667473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 508201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QINC(Carbamidomethyl)HIVDK MGYG000002438_00957 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22XE6@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QINDEIMAQIMEAITK MGYG000000212_00440;MGYG000000133_02955;MGYG000000184_00575;MGYG000000171_00241;MGYG000001338_02151 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.6 186801|Clostridia 1.0 G 1.0 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 0.6 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QINEAENRVDLQSGSIR MGYG000000243_03188;MGYG000002478_01929 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,2FNI1@200643|Bacteroidia,4AVYV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1224062 0 799613 0 0 0 0 0 0 0 900679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 871190 0 1104495 0 0 0 0 1106470 0 0 0 0 284065 0 0 0 0 0 0 0 684184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264588 0 0 511230 0 423115 0 0 0 0 0 0 0 393600 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178307 0 0 0 0 0 0 0 397324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248557 0 354024 0 0 0 0 362531 -(Gln->pyro-Glu)QINKDLAIQFK MGYG000000243_02696;MGYG000002171_02452 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FWW6@200643|Bacteroidia,4AWE3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1527671 0 1213884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1609258 0 1585262 0 0 0 0 1498954 0 0 277517 0 482833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 200213 0 0 0 0 0 0 292757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIQVDLPDIGHR MGYG000002274_01087;MGYG000002641_01949;MGYG000003899_02100;MGYG000002272_00718;MGYG000001300_02656;MGYG000003166_00234;MGYG000003291_01552 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 translation elongation 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 413384 397819 226751 0 904929 0 236206 0 0 170417 0 0 0 0 670716 0 454835 0 0 0 0 0 0 0 0 292342 0 0 835749 0 0 0 0 0 0 0 364759 0 662980 524766 0 0 339298 693199 598989 0 0 448352 0 0 449963 0 583250 0 291793 0 0 195619 0 0 0 503439 386384 0 0 373288 0 0 0 0 0 0 0 0 269378 0 0 0 0 0 457180 0 0 0 0 224816 0 0 0 0 0 0 547866 0 0 0 0 0 0 388105 132485 312750 0 486604 433926 0 0 0 0 0 0 0 259751 0 365956 291771 421741 0 595564 419536 466409 0 0 514288 0 0 174153 0 775241 0 453659 0 0 248019 0 0 0 298207 390501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128959 0 0 0 0 0 0 0 0 0 231393 0 237381 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIQVELPDIGHR MGYG000004679_00212 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000004679 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 translation elongation 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449858 0 0 0 0 427102 0 0 0 0 793129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1072072 0 0 0 0 0 0 0 0 0 624617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 944756 0 0 0 0 1152973 0 0 0 0 999003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609843 0 0 0 0 902912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1458325 0 0 0 0 1665636 0 0 0 0 2168002 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIQVYAEDAAK MGYG000002478_02937;MGYG000004797_02944;MGYG000002560_02890;MGYG000000236_02416 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1218773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1206713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QISAMILQK MGYG000000153_02121;MGYG000000245_00866;MGYG000002517_00989;MGYG000000271_02474;MGYG000002256_00937;MGYG000004271_00836;MGYG000000280_00287 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 0.8571428571428571 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 70618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 501453 0 0 714894 0 0 0 0 496596 0 0 0 0 0 573264 110110 476392 0 0 431370 0 0 0 0 0 396278 1007265 0 0 0 0 0 0 0 0 481505 378510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QISIAHIAR MGYG000000003_02555;MGYG000004536_01074;MGYG000001562_00614;MGYG000001420_00222 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,2FP6Q@200643|Bacteroidia,22U4U@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Succinate dehydrogenase fumarate reductase 1.0 frdB 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00240 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer2_3,Fer4_7,Fer4_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 543812 0 0 0 0 0 0 0 0 734502 0 0 0 0 0 0 0 0 1131002 0 0 0 0 0 0 695067 2158955 0 0 1578026 0 1545111 0 0 0 0 1511232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467040 0 0 0 0 0 0 0 0 399047 0 0 0 0 0 0 0 0 422151 0 0 0 0 0 0 0 610514 0 0 384762 0 275023 0 0 0 0 412853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121136 0 0 0 0 0 0 0 116478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QITEDTDKVIR MGYG000001306_02215 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,2FN99@200643|Bacteroidia,22WPD@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 seryl-tRNA synthetase 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 701671 0 0 0 0 526086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438497 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QITGKEPSK MGYG000000153_02121;MGYG000000179_03775;MGYG000002517_00989;MGYG000000271_02474;MGYG000000489_01891;MGYG000000133_02344;MGYG000000142_01918;MGYG000000255_01223;MGYG000001065_01063 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 0.4444444444444444 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 262455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1559485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QITITELGQR MGYG000002494_04127 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3WV6W@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 K 1.0 Transcriptional regulator PadR-like family 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 460311 0 554444 0 0 0 0 0 0 0 0 0 0 0 0 0 724309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 648271 0 0 0 1517201 0 1662150 1657145 2749399 0 0 0 1567584 0 0 0 0 0 0 0 1366239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 420407 0 0 0 0 0 782953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226833 0 0 0 0 0 0 0 0 0 0 0 0 191629 0 652933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 515177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QITLAHVITSPKPIVYR MGYG000000262_00817;MGYG000000077_01079 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG4810@1|root,COG4810@2|Bacteria,1V452@1239|Firmicutes,25DMT@186801|Clostridia,25ZJH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 E 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 ko:K04031 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534054 0 0 0 0 0 0 0 0 0 0 0 0 531005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 497008 0 433493 0 0 0 0 497814 -(Gln->pyro-Glu)QITMDTQDYTNNEK MGYG000001300_02598;MGYG000002641_02082;MGYG000002651_01603;MGYG000003899_02002;MGYG000002610_01434;MGYG000002272_02331;MGYG000003166_00861;MGYG000002274_01203 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788882 0 0 0 0 728800 0 0 0 0 687181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 767840 0 0 0 0 680681 0 0 0 0 830709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1369043 0 0 0 0 1349770 0 0 0 0 1452975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363835 0 0 0 0 540076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QITVSVIDPVGLHAR MGYG000000223_03916;MGYG000001421_00895 family d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae 1.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,3VR4T@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 G 1.0 phosphocarrier protein HPr 1.0 ptsH 1.0 - 1.0 - 1.0 ko:K11189 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1514720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 344620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QITVSVIDPVGLHARPATVAVNAASK MGYG000000223_03916 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,3VR4T@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 G 1.0 phosphocarrier protein HPr 1.0 ptsH 1.0 - 1.0 - 1.0 ko:K11189 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 954868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246699 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIVANAGK MGYG000002470_00024;MGYG000000355_02196;MGYG000001503_00482;MGYG000000044_03505;MGYG000000013_01093;MGYG000001661_02480;MGYG000003693_01240;MGYG000001313_00852;MGYG000002478_00380;MGYG000003363_02977;MGYG000003521_02097;MGYG000002171_01748;MGYG000000224_01773;MGYG000002218_01379;MGYG000000105_03063;MGYG000004899_00357;MGYG000003922_03103;MGYG000001925_02203;MGYG000002933_01569;MGYG000001787_00205;MGYG000004876_02137;MGYG000001306_00685;MGYG000001433_02375;MGYG000001364_01313;MGYG000003251_00039;MGYG000001345_00379;MGYG000004763_01826;MGYG000000243_00634;MGYG000002033_00862;MGYG000002438_00745;MGYG000001337_03744;MGYG000002455_00111;MGYG000001346_02504;MGYG000001489_00629;MGYG000001461_03937;MGYG000000236_02963;MGYG000000098_00786;MGYG000001789_02329;MGYG000003681_02583;MGYG000000138_02067;MGYG000001370_00105 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 0.7560975609756098 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 450278 0 0 0 0 0 0 0 0 0 0 0 85151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 569389 0 0 0 0 0 0 0 0 0 0 0 753816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1127927 0 0 0 0 0 0 0 0 0 0 0 279525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIVANAGKEGAVVVQK MGYG000002470_00024;MGYG000001503_00482;MGYG000000044_03505;MGYG000000013_01093;MGYG000001661_02480;MGYG000001313_00852;MGYG000002478_00380;MGYG000002171_01748;MGYG000000224_01773;MGYG000000105_03063;MGYG000004899_00357;MGYG000001925_02203;MGYG000003922_03103;MGYG000002933_01569;MGYG000004876_02137;MGYG000001345_00379;MGYG000004763_01826;MGYG000000243_00634;MGYG000002033_00862;MGYG000001337_03744;MGYG000002455_00111;MGYG000001346_02504;MGYG000000236_02963;MGYG000000098_00786;MGYG000001789_02329;MGYG000000138_02067;MGYG000003681_02583;MGYG000001370_00105 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 0.8571428571428571 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 466393 1090795 2084825 0 1566294 1007746 0 925582 0 969303 1126691 0 1745067 1091984 0 1498316 1546156 0 718616 0 642653 622123 0 867719 0 591541 0 0 0 846414 1593717 1400760 1799024 0 855663 0 845297 1619713 0 0 0 0 364636 0 0 0 0 0 279816 0 286624 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141903 0 0 0 0 0 0 0 339804 710907 0 676263 690449 0 463064 0 520199 682013 0 641668 336331 0 625150 328193 0 0 0 147070 387370 0 391784 0 281908 0 0 0 384126 653706 468294 444481 0 576356 0 0 379949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268393 0 0 0 0 0 243595 0 384925 0 0 450358 0 0 0 0 634664 0 0 0 0 0 0 0 0 313300 194968 151797 0 0 0 0 352838 0 -(Gln->pyro-Glu)QIVDHK MGYG000001311_00418;MGYG000000489_01431;MGYG000000301_00189;MGYG000000142_02037;MGYG000004055_01474;MGYG000001338_02781;MGYG000002528_01865;MGYG000000205_02177;MGYG000000164_02738;MGYG000001374_01170;MGYG000001698_04057;MGYG000000255_01813;MGYG000004271_00043;MGYG000001793_01088;MGYG000002298_00361;MGYG000004317_00991;MGYG000001319_01295;MGYG000000251_01802;MGYG000000233_02370;MGYG000000187_01733;MGYG000001310_00114;MGYG000004733_01001;MGYG000000242_01797;MGYG000002279_01045;MGYG000001193_00570;MGYG000002989_00885;MGYG000000216_02330;MGYG000002835_01006;MGYG000000031_02237;MGYG000000198_04914;MGYG000000154_01811;MGYG000000271_01088;MGYG000000146_01023;MGYG000000206_01061;MGYG000001496_03147;MGYG000000002_00856;MGYG000002517_02847;MGYG000000404_01611;MGYG000000179_04573;MGYG000000080_02281;MGYG000002492_00402;MGYG000004296_00416;MGYG000002145_00311 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia 0.27906976744186046 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 3731126 3545450 4163044 2402175 0 3217843 0 0 0 3831285 4928664 3721177 5380734 3861369 4522374 0 2539238 4972861 0 0 4550434 5634716 4619932 2435577 4260272 3651256 0 5635533 3520185 0 2258393 0 3230672 5027269 4275702 2872517 3397289 3082526 2252870 6236310 2592473 3307064 0 1898971 0 0 0 2823243 2829824 2161019 3650576 2291453 2277447 0 2854548 2482627 0 0 1916758 1281358 1880509 2627424 2337091 2565459 0 4297195 3269090 0 5200937 0 3355597 4181397 3677328 3004069 2897085 3528405 3724665 6066278 4750481 3018353 0 4328583 0 0 0 4005249 2834128 3129336 5002999 5030746 4705825 0 5083301 2586312 0 0 2596813 5577037 2823899 3188418 4805468 4494192 0 4881177 4397789 0 3808605 0 7414404 5333879 4159331 3634217 2678886 3884099 3451623 3438628 3462702 3651397 0 1954391 0 0 0 3805126 3370198 3703668 2993791 3029566 3917662 0 2802204 1974176 0 0 1073619 3043112 865209 3452462 3216354 2777121 0 3067011 3800446 0 4756113 0 3221745 2488103 3940770 2401890 3938796 4088828 6313152 8360105 5349555 5804034 0 5477816 0 0 0 9586945 8208787 5704792 3073823 13042168 7821677 0 6914514 723621 0 0 4357474 4018700 1829409 5127022 7332199 6449152 0 3221686 9717926 0 5622031 0 11114420 8683742 6903981 11575072 6654020 8747536 -(Gln->pyro-Glu)QIVDHKFVTVN(Deamidated)GK MGYG000004271_00043;MGYG000000154_01811;MGYG000000153_02069 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIVDHKHVLVN(Deamidated)GK MGYG000001193_00570;MGYG000002989_00885;MGYG000000142_02037;MGYG000004055_01474;MGYG000000216_02330;MGYG000002835_01006;MGYG000000031_02237;MGYG000001338_02781;MGYG000002528_01865;MGYG000004839_01287;MGYG000000164_02738;MGYG000000002_00856;MGYG000000404_01611;MGYG000002298_00361;MGYG000004317_00991;MGYG000001319_01295;MGYG000004296_00416;MGYG000000187_01733;MGYG000000251_01802;MGYG000001310_00114;MGYG000002279_01045;MGYG000004733_01001 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia 0.18181818181818182 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIVEISRRPEFLGK MGYG000002478_03891;MGYG000000044_00878;MGYG000000243_02790;MGYG000001780_04144 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,2FQ21@200643|Bacteroidia,4AMWE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Protein of unknown function (DUF3417) 1.0 glgP 1.0 - 1.0 2.4.1.1,2.4.1.11,2.4.1.8 1.0 ko:K00688,ko:K00691,ko:K16153 1.0 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 1.0 - 1.0 R00292,R01555,R02111 1.0 RC00005,RC00049 1.0 ko00000,ko00001,ko01000,ko01003 1.0 - 1.0 GH65,GT3,GT35 1.0 - 1.0 DUF3417,Glycogen_syn,Phosphorylase 1.0 2.4.1.1 1.0 GT35 1.0 GT35 1.0 GT35 1.0 glycogen phosphorylase. | glycogen(starch) synthase. | maltose phosphorylase. polyphosphorylase. | UDP-glucose--glycogen glucosyltransferase. This entry covers several enzymes from different sources that act in vivo on different forms of (1->4)-alpha-D-glucans.-!-Some of these enzymes catalyze the first step in the degradation of large branched glycan polymers - the phosphorolytic cleavage of alpha-1,4-glucosidic bonds from the non-reducing ends of linear poly(1->4)-alpha-D-glucosyl chains within the polymers.-!-The enzyme stops when it reaches the fourth residue away from an alpha-1,6 branching point, leaving a highly branched core known as a limit dextrin.-!-The description (accepted name) of the enzyme should be modified for each specific instance by substituting 'glycogen' with the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, etc. | The description (official name) varies according to the source of the enzyme and the nature of its synthetic product.-!-Glycogen synthase from animal tissues is a complex of a catalytic subunit and the protein glycogenin.-!-The enzyme requires glucosylated glycogenin as a primer; this is the reaction product of EC 2.4.1.186.-!-A similar enzyme utilizes ADP-glucose (cf. EC 2.4.1.21). [(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. | [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D- glucosyl](n+1) + H(+) + UDP. | D-maltose + phosphate = beta-D-glucose 1-phosphate + D-glucose. 1.0 1.0 1.0 1.0 Necroptosis;Biofilm formation - Escherichia coli;Metabolic pathways;Starch and sucrose metabolism;Insulin resistance;Glucagon signaling pathway;Biosynthesis of secondary metabolites;Insulin signaling pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIVENAGGEGSVVVNK MGYG000001562_02467;MGYG000000074_00757;MGYG000001546_00436;MGYG000001415_01066;MGYG000000003_00613;MGYG000003279_00515 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22UPC@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 288352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355341 0 0 0 0 0 409914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 500380 0 0 0 0 0 0 -(Gln->pyro-Glu)QIVENAGGEGSVVVNKVK MGYG000000074_00757;MGYG000000003_00613 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22UPC@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 258438 0 0 175454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376304 0 0 0 0 0 0 0 0 0 0 353679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 752955 0 0 0 0 0 0 0 0 757383 0 0 0 0 0 0 0 0 0 0 0 0 352255 0 0 0 0 0 0 0 0 0 0 610269 0 -(Gln->pyro-Glu)QIVGFLKDGC(Carbamidomethyl)EK MGYG000000029_02971;MGYG000003312_01933;MGYG000004763_00834;MGYG000000013_04188;MGYG000001306_01782;MGYG000001750_00741;MGYG000000196_03462;MGYG000001787_00809;MGYG000002478_03726;MGYG000001345_02371;MGYG000003681_00721;MGYG000000098_01490;MGYG000001346_03050 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,4AKZ7@815|Bacteroidaceae 0.46153846153846156 976|Bacteroidetes 1.0 S 0.46153846153846156 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 0.5384615384615384 serA 0.5384615384615384 - 1.0 1.1.1.399,1.1.1.95 0.5384615384615384 ko:K00058 0.5384615384615384 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 0.5384615384615384 M00020 0.5384615384615384 R01513 0.5384615384615384 RC00031 0.5384615384615384 ko00000,ko00001,ko00002,ko01000,ko04147 0.5384615384615384 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 0.5384615384615384 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 0.5384615384615384 0.5384615384615384 0.5384615384615384 0.5384615384615384 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 0.5384615384615384 none 1.0 0 0 0 0 848981 685723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726276 0 0 0 0 0 614559 0 0 0 0 356964 224536 0 0 0 0 0 0 208903 0 0 0 0 0 0 0 0 304610 0 0 0 0 0 0 0 0 0 453423 251796 0 0 0 0 315250 0 0 460838 0 0 380502 0 0 0 0 0 0 343807 0 0 0 0 0 0 0 0 214280 0 0 0 0 0 0 0 0 0 349623 359953 0 0 0 0 0 0 0 214348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIVGFLKDGC(Carbamidomethyl)EKFR MGYG000002478_03726 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIVLN(Deamidated)C(Carbamidomethyl)GEEPSVVANTVK MGYG000002515_04060;MGYG000002507_03180;MGYG000002494_02676;MGYG000002323_03824;MGYG000003390_03600;MGYG000002506_03866 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,3XN1I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797417 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 696784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIVLNC(Carbamidomethyl)GEEPSVVANTVK MGYG000002515_04060;MGYG000002507_03180;MGYG000002494_02676;MGYG000002323_03824;MGYG000003390_03600;MGYG000002506_03866 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,3XN1I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 439703 390143 292850 442811 314618 519255 353733 531669 0 493077 0 412182 388429 0 0 0 733756 0 453819 714588 0 413901 357199 0 0 0 488731 438334 0 352516 0 332262 566381 288092 0 242569 614281 1157413 897035 988588 1320131 2186586 1064140 882346 676976 1344672 588785 1177021 0 1053560 1129391 0 1251971 0 1332451 781543 1447653 2639952 0 1904997 1434832 943153 957350 0 1557262 1571482 0 1036529 1188496 778043 927826 686864 863164 1036148 514500 297233 0 0 448926 624528 491304 417336 489373 538248 283160 546532 0 0 431239 0 0 0 300655 473593 435861 337482 0 557471 560982 212854 0 0 362858 421016 0 536262 547509 500342 494697 462953 0 0 437950 470928 150319 0 291403 497769 0 307180 0 358415 0 433803 0 0 0 0 0 0 345864 0 0 516624 0 0 296109 0 0 0 230588 0 0 340392 299536 476462 449472 421181 0 346067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIVSHGHVAVN(Deamidated)GR MGYG000002485_02438;MGYG000004893_02153;MGYG000004828_01832 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia,36DJ1@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 S 1.0 Amidohydrolase family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 260261 0 0 0 0 0 0 0 573774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 536799 0 0 0 0 829186 0 0 830696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115070 0 0 0 0 485715 0 0 195427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348171 0 0 0 0 0 0 0 718715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399219 0 0 0 0 0 0 0 121881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIWLAR MGYG000002385_01670;MGYG000002836_00177;MGYG000000417_00990;MGYG000003425_04578;MGYG000000135_00904;MGYG000002835_00249;MGYG000000194_00148;MGYG000003074_01094;MGYG000002494_00954;MGYG000004740_00996;MGYG000004296_00563;MGYG000001466_01401;MGYG000000093_03264;MGYG000003365.1_01350;MGYG000002279_01345;MGYG000000198_05003;MGYG000000028_00551;MGYG000003386_02757;MGYG000002502_02035;MGYG000002513_00644;MGYG000000077_00742;MGYG000003500_01570;MGYG000000204_01919;MGYG000000337_00504;MGYG000000164_02309;MGYG000000650_00409;MGYG000004785_01595;MGYG000001714_03187;MGYG000002477_03371;MGYG000000251_00849;MGYG000002445_00508;MGYG000001637_00295;MGYG000001602_00896;MGYG000002140_02930;MGYG000000187_00017;MGYG000004719_00198;MGYG000003390_04838;MGYG000000280_00495;MGYG000004140_02145;MGYG000002415_03008;MGYG000004087_02771;MGYG000003381_00971;MGYG000001688_02232;MGYG000000242_00002;MGYG000000262_01894;MGYG000000233_01926;MGYG000003147_00384;MGYG000001027_00595;MGYG000004697_00980;MGYG000004691_01780;MGYG000004271_02671;MGYG000002247_02698;MGYG000000249_02765;MGYG000002500_02076;MGYG000004735_02560;MGYG000000172_02251;MGYG000000278_01794;MGYG000002772_02101;MGYG000002323_01869;MGYG000001617_03101;MGYG000000206_00307;MGYG000001379_00357;MGYG000000087_00675;MGYG000003184_02040;MGYG000004687_00694;MGYG000000909_00003;MGYG000000274_00640;MGYG000002534_02304;MGYG000002670_01394;MGYG000002212_01212;MGYG000000076_00222;MGYG000002492_01782;MGYG000000245_00328;MGYG000000140_00409;MGYG000000216_00894;MGYG000000325_00749;MGYG000002170_01655;MGYG000004842_00865;MGYG000001619_00780;MGYG000001607_01170;MGYG000000378_00736;MGYG000003360_04047;MGYG000003394_00456;MGYG000004313_00821;MGYG000004869_03499;MGYG000000179_01982;MGYG000004762_00052;MGYG000000255_00435;MGYG000003335_00558;MGYG000002552_01270;MGYG000001622_02998;MGYG000000038_00405;MGYG000000032_00759;MGYG000000127_02757;MGYG000001493_01515;MGYG000000312_00898;MGYG000001311_02799;MGYG000002256_02331;MGYG000001564_02958;MGYG000001065_01098;MGYG000000235_02801;MGYG000003702_00971;MGYG000002476_01918;MGYG000000205_01312;MGYG000002535_02257;MGYG000002528_02185;MGYG000000133_01122;MGYG000003427_02320;MGYG000001624_00366;MGYG000000271_00159;MGYG000001689_03339;MGYG000001615_01544;MGYG000000562_01465;MGYG000004879_02884;MGYG000000136_00740;MGYG000001319_00516;MGYG000001543_01619;MGYG000001531_01857;MGYG000001315_00603;MGYG000003486_01852;MGYG000002517_01594 domain d__Bacteria 1.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,22068@1506553|Lachnoclostridium 0.256198347107438 186801|Clostridia 0.8016528925619835 J 1.0 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit 1.0 rplT 1.0 - 0.8016528925619835 - 1.0 ko:K02887 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIYMAQAAESGKPEAIQEK MGYG000003266_00511;MGYG000002961_01439;MGYG000002775_01737;MGYG000001718_01380;MGYG000001642_01010;MGYG000004681_00360;MGYG000002919_00618;MGYG000000802_00143;MGYG000000188_00077 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CU7J@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 684665 0 0 0 0 0 0 0 0 0 0 453807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QIYVDHTK MGYG000000133_00237;MGYG000000216_00421 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 0.5 186801|Clostridia 1.0 M 0.5 Cobalt chelatase (CbiK) 0.5 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 0.5 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKAEADIAQER MGYG000003166_00739;MGYG000000195_00670;MGYG000001300_02372;MGYG000002619_01674;MGYG000000022_01424;MGYG000004679_00017;MGYG000002274_00872;MGYG000002545_01161;MGYG000002040_00949 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24IT1@186801|Clostridia,3WS1Z@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) 1.0 - 1.0 - 1.0 - 1.0 ko:K02109 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_B 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 3858420 0 5529745 3032394 0 4166001 218982 4811860 4243122 0 6284411 0 0 866264 3449878 6291149 3396963 2214685 4149850 4188073 0 3346120 531898 4151621 4052007 4444383 3214758 3011132 0 0 0 0 4501510 0 0 3521611 4379342 4707379 792894 0 806106 962524 0 465256 788664 1304603 786295 0 627063 0 0 764255 659088 563598 785457 381775 1472244 646909 0 528282 751397 517678 1003428 705682 665869 784282 0 0 0 0 818895 0 0 444435 680213 513977 348307 0 3678952 372351 0 3224866 466833 255268 3550072 0 4311417 0 0 391523 2205020 3025617 2234051 966107 2124096 885175 0 1841141 627340 183536 404148 238395 247514 616007 0 0 0 0 2109429 0 0 3492766 352770 3311280 1926467 0 1277397 1062067 0 1885205 1258456 1986333 958335 0 2469843 0 0 1278583 1782231 2507449 996267 891686 1488417 838425 0 0 841836 1010673 1278484 2489579 1997500 1383784 0 0 0 0 1647583 0 0 1442849 2040637 0 259449 0 287196 163835 0 131643 205341 65091 168379 0 445989 0 0 277966 139166 435894 408330 464353 416472 213501 0 377361 502228 382066 162678 364140 370924 541818 0 0 0 0 84638 0 0 294398 230128 398971 -(Gln->pyro-Glu)QKAEGLKR MGYG000002478_04161;MGYG000004797_00893 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,2FPDM@200643|Bacteroidia,4AMEQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 The glycine cleavage system catalyzes the degradation of glycine 1.0 gcvT 1.0 - 1.0 2.1.2.10 1.0 ko:K00605 1.0 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 1.0 M00532 1.0 R01221,R02300,R04125 1.0 RC00022,RC00069,RC00183,RC02834 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GCV_T,GCV_T_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aminomethyltransferase. tetrahydrofolate aminomethyltransferase. A component, with EC 1.4.4.2 and EC 1.8.1.4, of the glycine cleavage system, formerly known as glycine synthase.-!-The glycine cleavage system is composed of four components that only loosely associate: the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H protein. (6S)-5,6,7,8-tetrahydrofolate + N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]- L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + N(6)- [(R)-dihydrolipoyl]-L-lysyl-[protein] + NH4(+). 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;One carbon pool by folate;Glycine, serine and threonine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 188271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKAEVTIPAK MGYG000002517_00434 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 358630 257009 0 0 0 0 0 0 0 0 0 0 0 0 283481 0 0 147670 286030 218048 0 0 299049 0 0 0 0 546824 298698 190735 0 292921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394261 0 0 398485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246981 153893 159093 284314 0 0 188400 0 0 0 0 200903 151599 277403 0 1822427 0 0 0 0 0 0 1721560 1581962 0 0 0 0 1695293 1727067 0 1373328 0 1402717 0 0 0 0 0 1891935 1671631 2032808 0 0 1477940 0 0 0 0 1691319 1567963 1745790 0 911803 0 0 0 0 930086 0 897232 1197157 0 0 0 0 1168317 1417987 0 1069674 0 1344646 0 0 844748 0 844126 1128622 1453258 1038486 0 0 622672 0 0 0 0 828865 1169076 1043096 0 -(Gln->pyro-Glu)QKDFAASDR MGYG000000133_01279 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3XZ2A@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3485735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2470043 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKDFLAK MGYG000001338_02036;MGYG000004869_01160 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359854 0 0 0 0 0 -(Gln->pyro-Glu)QKDLSIVYTPLHGAGR MGYG000001313_01236;MGYG000002455_04364;MGYG000001346_01418;MGYG000002717_00478 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 592206 0 0 0 0 636065 0 0 0 0 591652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385749 0 0 0 0 316874 0 0 0 0 409977 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKDVYNIVLAC(Carbamidomethyl)HDK MGYG000000243_01741 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,2FMSQ@200643|Bacteroidia,4AKGR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 pepP 1.0 - 1.0 3.4.11.9 1.0 ko:K01262 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 AMP_N,Peptidase_M24 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Xaa-Pro aminopeptidase. X-Pro aminopeptidase. Generally membrane bound enzyme present in both mammalian and bacterial cells.-!-Belongs to peptidase family M24B. Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 434202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519871 0 0 0 0 391903 0 0 206698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242286 0 0 0 0 291255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKEAATENENR MGYG000000179_01759 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,268IA@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 O 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKEAVTELFR MGYG000003542_00743;MGYG000003415_00398;MGYG000000074_01933;MGYG000002082_00458;MGYG000000053_00721 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,2FNPH@200643|Bacteroidia,22UFD@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal protein L17 1.0 rplQ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02879 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Ribosomal_L17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 468815 0 282122 309517 435807 487715 0 322749 316644 417716 0 0 0 0 273667 329758 344877 0 0 150451 0 389829 0 550593 311957 279247 0 0 458932 457104 249573 0 388721 0 0 399064 303611 266986 0 0 426598 453083 571679 498593 0 392395 0 576790 0 0 0 0 421097 289194 169472 0 0 0 0 306744 0 369586 0 520090 0 0 546630 391865 190265 0 371758 0 0 391647 563839 292386 298346 0 0 358074 350095 432944 0 404277 809027 984116 0 0 0 0 806743 378631 650585 0 0 352307 0 0 0 319582 774392 190139 0 0 604034 268026 0 0 819469 0 0 605249 616836 336771 147530 0 626726 299743 340467 456557 0 483867 343665 292233 0 0 0 0 301765 466906 340342 0 425468 276778 0 518884 0 613599 377942 464333 0 0 405035 415099 374075 0 485716 0 0 415564 345782 471293 752647 0 922225 1452335 1119077 1262382 0 809291 1222233 1078768 0 0 0 0 967947 1145363 1107679 0 1695046 1677330 0 938012 0 840233 1108891 1124028 0 0 1202998 1448393 849205 0 595852 0 0 1035014 1404455 1077516 -(Gln->pyro-Glu)QKEIADGLASAER MGYG000002494_02408;MGYG000002506_03406;MGYG000002534_04893;MGYG000002477_00658;MGYG000002535_04275 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,3X0ZA@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) 1.0 atpF 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902600 1.0 - 1.0 ko:K02109 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664 1.0 ATP-synt_B 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613728 0 0 631086 1296790 0 0 0 1138089 0 0 0 0 0 0 1360070 0 0 0 0 989741 0 1334095 0 0 0 0 0 1785895 0 0 0 568145 0 0 0 0 0 0 0 0 496651 435603 0 0 0 0 0 0 0 0 0 0 749688 0 0 0 0 562936 0 0 0 0 0 0 0 1069914 0 0 0 910971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 592136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKEISAFIVEK MGYG000000164_00686;MGYG000000255_01556;MGYG000004740_00273;MGYG000001793_01807;MGYG000000205_02133 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,21YI4@1506553|Lachnoclostridium 0.4 186801|Clostridia 1.0 C 0.6 Acyl-CoA dehydrogenase, C-terminal domain 0.6 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 885384 0 912128 0 0 958381 0 794276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 844552 0 0 0 0 648983 0 0 0 0 0 0 0 0 0 0 346254 0 423316 0 0 222526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397526 0 0 0 0 0 0 0 0 0 0 114812 0 0 0 0 437020 0 244954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194892 0 0 0 0 0 0 0 0 0 0 0 0 469343 0 0 584691 0 503971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424215 0 0 0 0 635199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKELGYHVITDGEFR MGYG000002528_03006 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,248U0@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 methionine synthase, vitamin-B12 independent 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Meth_synt_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 892524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 673276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKELMER MGYG000002966_01704;MGYG000000806_02010;MGYG000000133_01628;MGYG000000301_00396;MGYG000003821_00638;MGYG000003012_01436 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3XZ91@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 9.98 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Ribosome;Metabolic pathways;Biosynthesis of secondary metabolites;Terpenoid backbone biosynthesis 1.0 none 1.0 0 809563 541984 0 0 396579 0 0 0 0 683303 0 1019366 0 0 537485 0 0 0 0 0 0 0 223804 503008 1885388 0 0 594533 0 0 211120 654455 0 0 1446743 0 829662 0 0 0 438060 0 0 0 0 0 0 138117 0 0 0 0 0 0 0 0 0 0 0 0 111910 0 130137 0 0 0 0 0 442664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321569 0 0 0 0 0 0 0 362108 333696 245092 0 0 0 126682 0 0 0 0 0 158316 0 502824 0 113281 0 0 5708119 0 0 295355 129419 0 0 0 344789 0 0 1819864 1265751 641584 0 260388 1040117 0 0 1713866 1657119 486181 801577 1569910 0 480127 0 0 155669 0 1582423 0 0 0 605288 315873 0 0 1117658 0 0 2019293 4918225 0 0 258617 0 887308 -(Gln->pyro-Glu)QKELQDMAQR MGYG000001346_02373;MGYG000002561_01358;MGYG000000224_01894;MGYG000003363_00932;MGYG000001313_00712;MGYG000004748_02076;MGYG000001661_00082;MGYG000003681_01828 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2825@1|root,COG2825@2|Bacteria,4NWPA@976|Bacteroidetes,2G3DE@200643|Bacteroidia,4AWDW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Membrane 1.0 - 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 273852 149381 690812 0 341263 214367 0 0 0 209705 358170 296751 0 325896 0 279535 544454 0 0 337137 0 393773 126113 257656 0 182778 351483 0 0 0 0 364921 0 303360 0 0 0 0 706629 637311 564334 569894 510391 554206 529291 654732 633517 772479 489968 1045502 0 725408 699832 606956 575224 187827 751372 464505 0 594088 310496 431461 528200 632446 661924 436295 489672 495696 0 640142 544674 590878 470772 771719 761445 653097 622340 641763 857167 720919 788480 966465 811000 673610 803500 857609 1262517 689807 0 848669 899803 561896 619767 1098218 693505 728100 0 702498 772536 656027 863605 727693 646629 1000387 740476 799556 0 256373 431285 696913 671989 819502 679567 711377 304519 277276 0 303743 369377 296955 0 203904 332630 0 303714 201803 0 0 312233 442096 172713 199932 301149 0 0 204232 0 180902 306410 272545 0 751725 290256 0 0 335246 348982 346973 0 510286 305376 0 0 205716 0 333978 429184 486792 0 445875 270570 324186 1064830 553745 0 0 0 648447 0 454744 408304 594938 0 408507 0 300348 338754 0 0 639200 528036 504402 0 473241 0 351127 669715 111373 266046 512459 -(Gln->pyro-Glu)QKELQDMMQR MGYG000000196_00111;MGYG000000013_00131;MGYG000002549_03516;MGYG000000029_03029;MGYG000003351_03212;MGYG000000054_01820;MGYG000001378_02728 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 317614 706522 0 0 932599 1113761 841290 0 1194210 0 0 746005 0 631669 0 0 409946 0 1183145 0 0 0 0 756213 0 0 0 0 0 0 0 0 0 900163 333671 407958 639669 0 765459 641380 0 0 595011 677570 228514 0 1073358 0 0 782769 0 668098 0 0 543277 0 584849 0 0 0 0 437243 0 0 0 0 0 0 449787 0 0 722754 471247 465756 425850 0 533740 0 0 0 521192 310764 576049 0 244063 0 0 0 0 0 0 0 386222 0 304727 0 0 0 0 0 0 0 0 0 0 0 221763 0 0 487744 473019 655181 0 0 571798 0 0 0 0 0 0 0 339723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 574481 0 0 0 0 0 0 0 0 0 0 0 260545 0 0 303738 371159 0 0 0 0 0 0 457682 0 0 324689 0 0 0 0 282837 0 0 0 0 0 0 272518 0 0 0 0 0 0 140930 0 0 0 334688 407261 -(Gln->pyro-Glu)QKELQELNEK MGYG000000243_03119 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1675811 0 0 0 0 0 0 0 761767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1848866 0 0 0 0 1992865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 751901 0 0 0 0 0 -(Gln->pyro-Glu)QKELQELQEK MGYG000002478_01528;MGYG000002560_00092;MGYG000004797_03114 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 1002696 0 0 0 0 0 416735 294496 1520986 0 0 1417024 0 368541 0 0 0 0 313501 0 0 0 0 400713 0 0 0 867722 761918 0 0 0 556130 614024 602877 0 672684 0 791977 0 0 0 0 0 680043 433555 1370890 0 0 1200963 0 0 0 0 0 0 0 0 0 533628 0 486246 0 675025 0 425193 767567 0 0 0 876903 541057 0 0 572625 0 1026099 0 0 0 0 0 348608 0 1258197 0 0 803326 0 705702 0 0 0 0 815103 0 0 297770 0 0 0 329585 0 0 0 0 0 0 616065 519392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520084 0 706774 0 1350171 0 0 0 0 0 490169 538005 1298275 0 0 1077114 0 1027049 0 0 0 0 800140 0 0 696085 0 476794 0 988679 0 803595 303619 0 0 0 1059047 893790 -(Gln->pyro-Glu)QKEVLEMPNLIEVQKDSYK MGYG000004271_02226;MGYG000000271_03641 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 - 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKFDMEDR MGYG000002619_02235;MGYG000002223_00611;MGYG000001255_01110;MGYG000001300_00291;MGYG000002610_00221;MGYG000003166_01338;MGYG000000195_01569;MGYG000003291_01730;MGYG000002651_00003;MGYG000000022_01320 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 2561677 2907083 4499904 3230745 903956 2600550 1568219 1601009 2448233 2845471 1832854 1654017 4653574 3738371 2828500 3203934 2998217 924398 6259231 3894597 1308504 2648809 741548 2270959 3006088 3133710 2698509 983802 0 1471454 2216310 2085944 4191788 4537331 1745160 1923482 2150722 4036450 4276029 5192475 5475032 3617608 3633886 4767203 5143866 2065215 4156453 939799 2965857 4207397 3809493 4525126 4318007 2817379 4133318 1192193 6467561 4254830 2143373 3945473 1311103 4440314 5700789 5160943 3889506 1601031 698992 3372021 5758047 4857921 4648439 4251487 1574375 3863301 4249986 5009985 730144 1283289 1081558 1072728 1118569 640423 1135081 901346 1080988 575239 1570543 688876 1318515 903420 904576 1066237 596140 1540644 891681 744113 590124 442682 1753259 803659 880257 801852 851846 1818645 559085 866922 939371 1395913 861581 1251728 499902 1146232 980631 997275 2481114 3755274 5497379 2694893 3854794 5066207 4512676 1565963 3801852 3870376 3919923 5195110 3852831 3098560 3277280 3855106 3188670 2072982 5509905 3451065 3580163 3519582 2124202 2778934 4111580 3438095 3432852 2516183 2023504 3973486 4878717 3396363 5476989 4333277 578992 2219549 3417993 6732702 0 0 535714 0 0 149777 0 0 0 219053 0 0 120411 0 201738 147282 0 1773252 0 0 0 0 1798402 0 0 0 0 1719926 0 0 200975 227656 529891 0 0 0 0 616457 -(Gln->pyro-Glu)QKFGHVK MGYG000000243_03119 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 2518121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3323431 0 0 0 0 3390638 0 0 204004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322984 0 0 96019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95442 -(Gln->pyro-Glu)QKIAPIAGAK MGYG000000271_02100;MGYG000002517_00544;MGYG000000245_02023 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 268270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1508633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKIEVTIPAK MGYG000002492_02675 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,27JIP@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480484 0 1524109 0 1753602 0 0 0 0 0 0 0 0 0 0 0 0 1922581 356577 514060 0 0 1176318 0 0 558957 0 1802142 0 0 0 0 1600815 0 0 0 570934 1871209 972948 0 3998342 0 1966981 0 0 0 0 0 0 0 0 0 0 0 0 691922 978018 928035 0 0 1044063 0 0 1165975 0 1599673 0 0 0 0 3507092 0 0 0 1120115 3198648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKIEVTIPMK MGYG000002528_01889 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,269H5@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 348539 368279 0 0 579402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 491041 0 370729 0 0 0 0 0 0 0 0 204210 0 0 0 0 301987 0 384794 201955 0 0 432915 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104439 0 501306 0 0 0 0 0 0 0 0 586325 0 0 0 0 143277 0 1706786 672499 0 0 835031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1979417 0 590393 0 0 0 0 0 0 0 0 770889 0 0 0 0 793459 0 229751 242045 0 0 210859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188662 0 0 0 0 0 0 0 0 149723 0 0 0 0 233427 0 258719 148628 0 0 699030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293697 0 142501 0 0 0 0 0 0 0 0 342241 0 0 0 0 707158 -(Gln->pyro-Glu)QKIEVTIPVK MGYG000000484_01496;MGYG000004733_00624;MGYG000000087_01289;MGYG000000002_00056;MGYG000000562_01970;MGYG000000038_01170;MGYG000004317_01434;MGYG000000205_02153;MGYG000000216_02638;MGYG000004869_04439;MGYG000001374_02466;MGYG000004519_00241;MGYG000002279_00296;MGYG000002835_00316;MGYG000004263_00951;MGYG000002992_01592;MGYG000000135_03575;MGYG000000249_00881;MGYG000000179_05419;MGYG000001367_04105;MGYG000003984_01028;MGYG000003684_03074;MGYG000004039_00581;MGYG000003012_02718;MGYG000004735_02698;MGYG000001607_01765;MGYG000002393_01024;MGYG000004842_00271;MGYG000004691_01360;MGYG000001571_02605;MGYG000000172_03322;MGYG000000806_01841;MGYG000002234_01596;MGYG000001027_00049;MGYG000000301_01176;MGYG000002945_01017;MGYG000000242_01723;MGYG000000201_01390;MGYG000000417_00332;MGYG000000140_00197;MGYG000000127_00990;MGYG000000359_01150;MGYG000002445_02284;MGYG000004689_01666;MGYG000001689_00254;MGYG000000251_02361;MGYG000001303_00122;MGYG000002946_03244;MGYG000003821_01882;MGYG000001338_01148;MGYG000000233_03002;MGYG000000278_00992;MGYG000000325_01136;MGYG000000200_01813;MGYG000000164_02141;MGYG000000187_02100;MGYG000000217_01334;MGYG000003783_01852;MGYG000000198_05420;MGYG000004087_02933;MGYG000000133_02532;MGYG000000050_01293;MGYG000001199_01379;MGYG000000312_00823;MGYG000000142_00063;MGYG000002212_00396;MGYG000003335_01038;MGYG000001531_03045;MGYG000001698_02999;MGYG000000031_00635;MGYG000002202_00135;MGYG000004799_00574;MGYG000001315_00409;MGYG000001065_00847;MGYG000004630_00387;MGYG000000139_02374;MGYG000001617_02330 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3XZRY@572511|Blautia 0.2727272727272727 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1429353 1582510 1034911 934725 1563860 1733117 954488 1686116 1143752 1525099 1518201 1366282 2006496 1451801 2165101 1641909 1617690 2798705 1224248 1512015 1541140 1814782 2467718 1157316 1601243 1213646 1305490 2916404 1631774 1538642 988977 1555015 1084381 1391696 1316528 1303510 1160085 1133250 1708431 2440319 1494448 1799465 1251195 0 1484724 1982217 1484459 1517945 1097170 1522666 1661848 0 1205988 1128691 1648583 1648174 1259996 1475383 1319377 671292 1117166 1237711 1685270 1413216 1575297 1414424 1490525 1421354 2750723 1461476 1227329 1898322 1909685 1521810 1409549 1342299 1872066 2350482 1730896 1334858 1441739 1733577 1513999 2281043 1568071 1864972 1274699 2119355 1976391 1745883 1996663 1915532 1626052 1901292 1764144 1865395 2002476 2114457 2254194 1444605 1736546 2040647 2184129 2671170 1550050 2144329 1700159 1885374 1813117 2284976 2134971 1592297 1800815 1547005 835080 1837840 1115949 693739 1423593 866992 680613 639303 736932 894533 1179506 955229 1327466 1037075 685388 1266548 1089022 774491 643851 752623 870900 813924 705281 1136412 638426 717491 893258 965320 1117347 971344 1479118 1309757 1224993 635819 888226 667243 782943 1645313 1821524 2188652 2488187 2315658 973824 1685104 2592286 1676541 1374028 2100666 1631421 1704943 1691359 2058727 1983067 2451605 1681610 1346955 2209140 833081 2224568 1958486 1787815 1361391 1767007 0 1650621 2154354 2033424 953403 2146946 2204590 3632013 2146263 1535833 1524831 1077597 1968180 -(Gln->pyro-Glu)QKIEVTIPVKGNIIR MGYG000000301_01176;MGYG000002945_01017;MGYG000000201_01390;MGYG000000417_00332;MGYG000004733_00624;MGYG000000002_00056;MGYG000000142_00063;MGYG000002835_00316;MGYG000000562_01970;MGYG000004317_01434;MGYG000002212_00396;MGYG000000249_00881;MGYG000000251_02361;MGYG000000031_00635;MGYG000003821_01882;MGYG000001338_01148;MGYG000000216_02638;MGYG000004735_02698;MGYG000001315_00409;MGYG000000200_01813;MGYG000000187_02100;MGYG000000806_01841;MGYG000002234_01596;MGYG000000133_02532 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3XZRY@572511|Blautia 0.625 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 1251349 2069708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 455147 1296687 1231575 0 0 0 0 537373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 817030 518487 0 0 0 0 0 0 0 1973983 568062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 867840 1103047 982526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 847502 1150236 1846256 0 0 0 0 935382 -(Gln->pyro-Glu)QKITEDNVQAIALGTDKK MGYG000000243_01847 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 542950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581605 0 0 0 0 261991 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKLESQISTLYGGR MGYG000002506_02820;MGYG000002534_00540;MGYG000002494_01794;MGYG000002515_03062;MGYG000002477_04931 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,41F7V@629|Yersinia 0.6 1236|Gammaproteobacteria 1.0 O 1.0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins 1.0 ftsH 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.0 - 1.0 ko:K03798 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000,ko01002,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,FtsH_ext,Peptidase_M41 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 530079 0 0 0 0 0 0 409658 0 0 0 0 0 0 0 0 0 0 0 455306 0 922477 0 0 0 0 0 0 0 0 949449 0 0 0 0 516182 0 0 763228 0 0 872704 530640 0 626276 581209 0 0 0 0 0 0 0 0 544431 0 0 1001693 0 696889 0 0 0 0 905159 0 0 0 532433 0 0 0 0 544317 0 0 0 0 0 345277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 198685 0 0 238384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKLMMDASTSR MGYG000000003_00816;MGYG000003279_01723 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,2FMVP@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG10142 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Porin_2,SH3_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 149259 0 0 0 0 0 0 0 0 0 588873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKLPSNN(Deamidated)GGFK MGYG000000243_02784;MGYG000001780_04138;MGYG000001345_00972;MGYG000002478_03897;MGYG000000044_00884;MGYG000002549_00555 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1830@1|root,COG1830@2|Bacteria,4NEUM@976|Bacteroidetes,2FKZ7@200643|Bacteroidia,4APQV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes 1.0 fbaB 1.0 - 1.0 4.1.2.13 1.0 ko:K11645 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DeoC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1002603 0 0 0 0 1304754 0 0 0 0 1552347 0 0 0 0 1630204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 487499 0 0 0 0 579981 0 0 0 0 0 0 0 0 0 776293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 831239 0 0 0 0 1807235 0 0 0 0 1797298 0 0 0 0 1694936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660262 0 0 0 0 541607 0 0 0 0 0 0 0 0 0 2019717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 420124 0 0 0 0 910026 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKLVSADEAVK MGYG000002517_02708;MGYG000000271_00943;MGYG000000245_03528;MGYG000004414_01832;MGYG000004271_01186 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Acetyl-CoA hydrolase transferase 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKPLRVILN(Deamidated)GLGK MGYG000000245_00061;MGYG000000251_02115;MGYG000000312_02568;MGYG000000262_01832;MGYG000000127_05084;MGYG000000404_00348;MGYG000003425_04615;MGYG000001606_02183;MGYG000000187_00466;MGYG000002528_00119;MGYG000000198_05683 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.36363636363636365 186801|Clostridia 0.8181818181818182 S 0.8181818181818182 Psort location Cytoplasmic, score 8.87 0.36363636363636365 - 0.8181818181818182 - 1.0 - 0.8181818181818182 - 0.8181818181818182 - 0.8181818181818182 - 0.8181818181818182 - 0.8181818181818182 - 0.8181818181818182 - 0.8181818181818182 - 1.0 - 1.0 - 1.0 GGGtGRT 0.8181818181818182 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8181818181818182 0.8181818181818182 0.8181818181818182 0.8181818181818182 0.8181818181818182 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKPVFVEDAK MGYG000002494_00281 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation 1.0 metE 1.0 - 1.0 2.1.1.14 1.0 ko:K00549 1.0 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 1.0 M00017 1.0 R04405,R09365 1.0 RC00035,RC00113,RC01241 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iJN746.PP_2698 1.0 Meth_synt_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. tetrahydropteroylglutamate-homocysteine transmethylase. Requires phosphate.-!-The enzyme from Escherichia coli also requires a reducing system.-!-Unlike EC 2.1.1.13 this enzyme does not contain cobalamin. 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Selenocompound metabolism;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 855314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 615500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKPWGQK MGYG000002791_00401 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__|m__MGYG000002791 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,36EGU@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1158225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 593972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 543799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 999952 0 0 -(Gln->pyro-Glu)QKQAETGIK MGYG000002281_00379;MGYG000001789_01205;MGYG000001313_01603;MGYG000001337_02813;MGYG000004763_01996;MGYG000002478_04391;MGYG000000224_02138;MGYG000004797_00652;MGYG000000196_04607;MGYG000004876_02961;MGYG000001787_00293;MGYG000001346_00290 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,2FN9P@200643|Bacteroidia,4AN2N@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 xylA 1.0 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 1.0 5.3.1.5 1.0 ko:K01805 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 - 1.0 R00878,R01432 1.0 RC00376,RC00516 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 xylose isomerase. D-xylose ketol-isomerase. Contains two divalent metal ions, preferably magnesium, located at different metal-binding sites within the active site.-!-The enzyme catalyzes the interconversion of aldose and ketose sugars with broad substrate specificity.-!-The enzyme binds the closed form of its sugar substrate (in the case of xylose and glucose, only the alpha anomer) and catalyzes ring opening to generate a form of open-chain conformation that is coordinated to one of the metal sites.-!-Isomerization proceeds via a hydride-shift mechanism. alpha-D-xylose = alpha-D-xylulofuranose. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 655546 793219 1207015 959492 1060824 0 1079099 1109939 0 1555406 1104980 1305543 0 1162747 982704 966206 1075647 424281 1301677 0 0 0 330582 0 0 1338401 0 426582 915008 1280677 0 1121553 730747 0 1221099 912394 784821 709623 698696 719739 500184 693707 906316 0 436974 755507 0 986810 947431 845956 0 698637 783505 568638 517862 682698 813844 0 0 0 719428 0 0 661063 0 807271 708842 590277 0 937696 547628 0 725430 346419 614136 599962 796999 807840 888109 925157 898774 0 897663 1128335 0 1357799 784073 1014990 0 892241 555068 630700 803931 2045946 971193 0 0 0 1215090 0 0 1000789 0 1500513 855070 1127347 0 922368 732619 0 875717 1268506 758473 593608 0 290143 363620 276215 249089 0 0 430501 0 391009 225193 520919 0 352876 0 0 526058 582060 862355 0 0 0 282920 0 0 498957 0 576081 335936 478114 0 337732 549527 0 0 0 454821 0 422869 332520 328296 420711 946762 0 479059 620274 0 564165 717461 592776 0 455576 431875 408254 648894 319108 467221 0 0 0 0 0 0 813488 0 0 629260 645502 0 481457 0 0 1091299 354215 702643 642546 -(Gln->pyro-Glu)QKQEETGIK MGYG000003681_01596 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,2FN9P@200643|Bacteroidia,4AN2N@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 xylA 1.0 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 1.0 5.3.1.5 1.0 ko:K01805 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 - 1.0 R00878,R01432 1.0 RC00376,RC00516 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 xylose isomerase. D-xylose ketol-isomerase. Contains two divalent metal ions, preferably magnesium, located at different metal-binding sites within the active site.-!-The enzyme catalyzes the interconversion of aldose and ketose sugars with broad substrate specificity.-!-The enzyme binds the closed form of its sugar substrate (in the case of xylose and glucose, only the alpha anomer) and catalyzes ring opening to generate a form of open-chain conformation that is coordinated to one of the metal sites.-!-Isomerization proceeds via a hydride-shift mechanism. alpha-D-xylose = alpha-D-xylulofuranose. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2041135 0 0 0 0 1747789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 419182 0 0 0 0 361895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312403 0 0 0 0 292654 0 0 0 0 525471 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKQEFQTK MGYG000001313_00977;MGYG000004748_00249 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,2FPTR@200643|Bacteroidia,4AMZ6@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 - 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1163971 0 0 0 0 651237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303978 0 0 0 0 226103 0 0 0 0 216187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1069800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKQPVDYVNPLMGTDSK MGYG000000196_01625;MGYG000001378_03102;MGYG000001345_01444;MGYG000002281_00094 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FMXD@200643|Bacteroidia,4APMR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Glycosyl hydrolase family 92 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_92 1.0 3.2.1.113|3.2.1.- 1.0 GH92 1.0 GH92 1.0 GH92 0.75 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 624348 0 0 877851 0 655340 882020 898817 0 721165 413933 0 0 694832 0 0 0 0 697864 0 788008 466852 0 793238 0 819658 774109 0 0 0 0 0 0 0 0 855595 1142878 0 443174 0 0 1070011 0 818956 569717 748547 0 686417 703500 0 0 820791 0 0 0 0 693462 0 642371 706626 0 552218 0 639830 655737 0 0 0 0 0 0 0 0 581116 741424 0 0 0 0 0 0 0 574608 0 0 0 322716 0 0 0 0 0 0 0 591551 0 0 0 0 374999 0 0 0 0 0 0 0 0 0 0 0 615133 0 0 395325 0 0 334731 0 520478 405357 0 0 221959 0 0 0 0 0 0 0 0 425753 0 0 353667 0 392806 0 0 367698 0 0 0 0 0 0 0 0 389646 381859 0 0 0 0 0 0 621969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 537106 0 0 0 0 0 0 0 0 0 0 0 348431 0 0 -(Gln->pyro-Glu)QKTDIPATVK MGYG000001300_02212 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WGQK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 426122 510537 724070 570316 0 391585 110159 214346 309082 0 242699 0 0 582807 0 0 532897 0 612123 606003 0 617717 264715 0 0 443223 521013 153401 0 196554 0 265602 580572 653883 0 255578 189279 716564 1966799 1309249 1595100 1593461 890356 1158549 1972910 628290 2240825 0 1067632 1255303 0 1950052 0 0 1403474 567230 1894866 1598525 0 761318 696267 1178041 0 1459568 1348997 834081 0 1288221 1413739 859010 1374217 1695052 0 1475115 1767226 1272566 0 169920 0 0 254098 0 0 0 0 0 262584 125837 0 0 0 0 0 704167 0 231652 0 157911 482814 0 0 0 0 460672 0 0 0 264836 138021 334309 0 0 0 143300 781372 675908 1138036 718560 762734 943250 867739 335171 568492 0 773924 1002850 0 776077 0 0 635918 318586 795918 627608 0 1170053 0 817265 0 652486 957329 514157 0 1010659 867625 709163 967660 789214 0 916021 666072 1113162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1245424 0 0 0 0 1186995 0 0 0 0 1101944 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKTGLMIDAYFSGTK MGYG000002528_01426 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKTGLVIDAYFSGTK MGYG000001617_02316;MGYG000002517_00259;MGYG000001619_01501;MGYG000004630_02409;MGYG000000389_02030 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 0.6 186801|Clostridia 1.0 C 0.6 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502715 646591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1733432 1643958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1559767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2751494 1978669 0 0 0 -(Gln->pyro-Glu)QKVDLNTFSDEEVLR MGYG000002494_02481;MGYG000002500_00412;MGYG000002534_04618;MGYG000002477_00983 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0085@1|root,COG0222@1|root,KOG0214@2759|Eukaryota,KOG1715@2759|Eukaryota,39VWS@33154|Opisthokonta,3BM6Z@33208|Metazoa,3DDNE@33213|Bilateria 1.0 33208|Metazoa 1.0 K 1.0 DNA-directed 5'-3' RNA polymerase activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7,Ribosomal_L10,Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1217271 0 0 0 1728107 0 0 0 0 0 0 0 0 0 0 0 0 1040801 0 0 1736984 0 1720865 1087619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKVEVTIPMKGSYIR MGYG000000271_01273;MGYG000004271_02465 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKVMLEGILDISK MGYG000002517_01337 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,25BET@186801|Clostridia 1.0 186801|Clostridia 1.0 NT 1.0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). 1.0 - 1.0 - 1.0 - 1.0 ko:K03406 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 MCPsignal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKVTDVEGK MGYG000002515_03209;MGYG000002506_02967 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 607116 0 0 1022288 546734 683410 408651 817473 0 0 0 0 1189403 0 0 0 0 888570 0 1159071 0 1071780 889861 0 0 0 0 0 0 0 494776 818204 0 0 0 593722 0 0 0 0 0 371261 0 262531 0 268535 0 0 0 0 0 0 0 0 0 0 0 233233 0 220908 0 0 0 0 0 0 0 0 0 227518 0 0 0 0 0 0 1349289 0 0 1434070 683561 1089828 1321842 984579 0 0 0 0 941386 0 0 0 0 1104328 0 1433030 0 1338945 1206584 0 0 0 0 0 0 0 867910 918919 0 0 0 1044760 0 0 1041937 0 0 1514113 1078848 1549681 817878 1771926 0 0 0 0 977049 0 0 0 0 0 0 1158468 0 0 946401 0 0 0 0 0 0 0 0 1407940 0 0 0 0 0 0 0 0 0 105183 0 0 115266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKVVAAEVENVK MGYG000000271_01229;MGYG000002517_01330 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 'glutamate synthase 1.0 gltA 1.0 - 1.0 1.4.1.13,1.4.1.14 1.0 ko:K00266 1.0 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 1.0 - 1.0 R00093,R00114,R00248 1.0 RC00006,RC00010,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,NAD_binding_8,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate synthase (NADPH). | glutamate synthase (NADH). NADPH-glutamate synthase. | NADH-glutamate synthase. The reaction takes place in the opposite direction.-!-The protein is composed of two subunits, alpha and beta.-!-The alpha subunit is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.4).-!-The beta subunit transfers electrons from the cosubstrate.-!-The NH3 is channeled through a 31 A channel in the active protein.-!-In the absence of the beta subunit, coupling between the two domains of the alpha subunit is compromised and some ammonium can be produced.-!-In the intact alphabeta complex, ammonia production only takes place as part of the overall reaction.-!-Formerly EC 2.6.1.53. | A flavoprotein (FMN).-!-The reaction takes place in the direction of L-glutamate production.-!-The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2). 2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH. | 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH. 1.0 1.0 1.0 1.0 Nitrogen metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1316802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 917146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKVYSVEAAK MGYG000000164_00686;MGYG000000271_02102;MGYG000002517_00542 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1973887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QKYVKPLATGEK MGYG000002517_00542;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87037 0 0 217184 0 0 0 0 0 0 156097 94592 63366 0 0 99219 0 132854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102099 0 0 131110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 807500 0 0 0 0 0 0 994461 921225 624838 0 0 745164 0 739714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 580431 0 0 736915 0 653351 -(Gln->pyro-Glu)QLAAENFGESVEETPASSTAR MGYG000002494_03341 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1080@1|root,COG1925@1|root,COG3412@1|root,COG1080@2|Bacteria,COG1925@2|Bacteria,COG3412@2|Bacteria,1MUT8@1224|Proteobacteria,1RRCZ@1236|Gammaproteobacteria,3WVVD@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 PEP-utilising enzyme, N-terminal 1.0 dhaM 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006476,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033554,GO:0033558,GO:0034983,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0047324,GO:0050896,GO:0051716,GO:0071704,GO:0098732,GO:0140096,GO:1901564 1.0 2.7.1.121 1.0 ko:K05881 1.0 ko00561,map00561 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000,ko02000 1.0 - 1.0 - 1.0 iECs_1301.ECs1703,iSF_1195.SF1201,iS_1188.S1285,iUTI89_1310.UTI89_C1391,iZ_1308.Z1969 1.0 EIIA-man,PEP-utilisers_N,PEP-utilizers,PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 696755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 684635 0 601686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLAAYGHMGR MGYG000001300_00585;MGYG000000573_01026;MGYG000002059_01607;MGYG000000084_01929 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3WGI3@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme 1.0 metK 1.0 - 1.0 2.5.1.6 1.0 ko:K00789 1.0 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 1.0 M00034,M00035,M00368,M00609 1.0 R00177,R04771 1.0 RC00021,RC01211 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N,YgbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methionine adenosyltransferase. S-adenosylmethionine synthetase. Formerly EC 2.4.2.13. ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L- methionine. 1.0 1.0 1.0 1.0 Biosynthesis of amino acids;Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 329642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 510499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLADKFGFEK MGYG000001761_01355;MGYG000000084_00730;MGYG000002148_01347;MGYG000004732_00468;MGYG000000573_00769 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WHKM@541000|Ruminococcaceae 0.8 186801|Clostridia 1.0 G 1.0 Kinase, PfkB family 0.8 - 1.0 - 1.0 2.7.1.45 1.0 ko:K00874 1.0 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 1.0 M00061,M00308,M00631 1.0 R01541 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-dehydro-3-deoxygluconokinase. KDG kinase. The enzyme shows no activity with 2-dehydro-3-deoxy-D-galactonate. cf. EC 2.7.1.178. 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D- gluconate + ADP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Metabolic pathways;Carbon metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6775867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3720957 0 0 0 0 5115549 0 0 0 0 3396477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3200184 0 0 0 0 2904890 0 0 0 0 4477022 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLADKFHFEK MGYG000002641_01227;MGYG000002272_02009;MGYG000002619_01740;MGYG000004679_00158;MGYG000000022_00356;MGYG000000195_01974;MGYG000002274_00782;MGYG000002610_02119;MGYG000003166_00504;MGYG000003921_02029;MGYG000000039_01372;MGYG000002545_01709;MGYG000001255_00803;MGYG000002224_01974 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WHKM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Kinase, PfkB family 1.0 - 1.0 - 1.0 2.7.1.45 1.0 ko:K00874 1.0 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 1.0 M00061,M00308,M00631 1.0 R01541 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-dehydro-3-deoxygluconokinase. KDG kinase. The enzyme shows no activity with 2-dehydro-3-deoxy-D-galactonate. cf. EC 2.7.1.178. 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D- gluconate + ADP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Metabolic pathways;Carbon metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 616150 674312 715916 686452 771278 810174 838837 674516 752456 903752 599807 614865 646621 844791 881883 625582 834827 2631783 749557 682900 694433 662305 2231486 791918 643312 810913 714006 2244710 741559 789616 722837 631348 706095 915695 866847 743424 626105 600906 763433 426101 624946 757181 509281 619619 665847 755185 818931 530636 570271 623061 616726 729910 727802 548044 723867 2367022 799190 875906 388613 543745 2951467 512328 739271 821702 740187 2578168 306012 634690 456067 583689 521367 768513 559767 532622 777549 688424 643587 721207 734146 885666 864261 724379 741455 909391 746660 810684 686715 737628 645541 745410 659357 742644 605836 2570302 526798 543344 614904 587251 2543966 955826 714627 740424 674833 3205853 769856 711040 792184 785126 517123 713143 819235 638873 809030 806258 778640 1009650 1038732 946729 728968 1288731 1198623 756170 1117002 1012935 1085479 987443 1294634 1157336 930456 730892 993667 2260522 1347962 967443 1113747 1060259 4092235 521372 1356657 1189566 1003633 2666217 697224 1218475 1020067 1042337 1172353 1564952 1208044 1132037 1057541 953494 542918 428420 534634 613134 725414 615316 579611 635319 588070 587566 537605 497236 495429 547914 509510 480254 615229 2633381 471504 533793 524676 648463 2797189 500747 430807 552791 519787 3321620 617617 723828 610290 552433 431746 713665 1122495 571311 613875 720579 -(Gln->pyro-Glu)QLADYLEITDVLDKFPSK MGYG000000251_00368;MGYG000001456.1_01658;MGYG000000245_01185 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 V 1.0 Psort location CytoplasmicMembrane, score 1.0 - 1.0 - 1.0 - 1.0 ko:K02003 1.0 - 1.0 M00258 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1 1.0 - 1.0 - 1.0 ABC_tran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLAELPR MGYG000002494_03637 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,3WX04@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine 1.0 hisD 1.0 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.1.1.23 1.0 ko:K00013 1.0 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 1.0 M00026 1.0 R01158,R01163,R03012 1.0 RC00099,RC00242,RC00463 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECUMN_1333.ECUMN_2362,iG2583_1286.G2583_2541,iUTI89_1310.UTI89_C2293,ic_1306.c2547 1.0 Aminotran_1_2,Histidinol_dh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 histidinol dehydrogenase. - Also oxidizes L-histidinal.-!-The Neurospora enzyme also catalyzes the reactions of EC 3.5.4.19 and EC 3.6.1.31. H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Biosynthesis of secondary metabolites;Histidine metabolism;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 80558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410895 0 337860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLAEQTKNSTEQITR MGYG000004271_01025 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,25BET@186801|Clostridia 1.0 186801|Clostridia 1.0 NT 1.0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). 1.0 - 1.0 - 1.0 - 1.0 ko:K03406 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 MCPsignal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLAGMRGLIANTSGTTIEIPIR MGYG000001756_02184 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__UBA1394|s__UBA1394 sp900538575|m__MGYG000001756 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1422125 0 88881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLAMHVAASKPEFVKPEDVSAEVVEK MGYG000002494_03067 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 893249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 620108 1080154 0 868968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLANKR MGYG000000301_00161;MGYG000002845_00979;MGYG000004733_00969;MGYG000001619_00833;MGYG000001367_00350;MGYG000002966_02574;MGYG000000398_00951;MGYG000000179_04599;MGYG000004735_01600;MGYG000000233_02344;MGYG000000198_04888;MGYG000001315_01337;MGYG000000133_00046;MGYG000001379_01346;MGYG000000262_00147 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia 0.4 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 434294 375742 594668 74384 0 1005449 334723 250091 701485 537486 860669 0 0 516708 633655 0 559833 0 0 0 376326 1698900 0 545963 0 508064 655614 0 202669 0 0 471540 853499 544104 580850 0 610835 671703 333260 282748 302005 298326 0 530792 284424 288491 249745 412248 80948 0 0 231666 389423 0 396194 0 0 0 473250 458344 0 425868 0 306760 384339 0 386939 0 0 0 238584 254012 238195 0 275668 0 344719 467629 795702 495237 0 588540 285799 538966 403246 490785 414029 0 0 462079 660713 0 490119 0 0 0 507841 1071084 0 643269 0 453140 565788 0 462008 0 0 548629 678141 710656 485366 0 487734 614135 484450 736044 289524 647753 0 523405 743040 452905 439972 570946 411650 0 0 412093 375792 0 579404 0 0 0 0 646749 0 467407 0 79726 461580 0 411863 0 0 1043849 299071 528513 612868 0 426586 284537 1590472 1746643 1883547 4001945 0 1191406 2669611 1128278 1336350 2472663 4520242 0 0 5226199 2408885 0 1246270 0 0 0 1874388 1682658 0 2283787 0 1802888 3236670 0 3672019 0 0 1800166 6396292 2532203 2313523 0 2324903 1853091 -(Gln->pyro-Glu)QLANSSIQGDQLKK MGYG000002834_00586;MGYG000003697_00203 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,2FNI1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 696292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLAYEIQK MGYG000002772_02524;MGYG000002528_01544;MGYG000000028_01782 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds together with S18 to 16S ribosomal RNA 1.0 rpsF 1.0 - 1.0 - 1.0 ko:K02990 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 154642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 973949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLC(Carbamidomethyl)DIGKR MGYG000000031_02924;MGYG000000142_01607 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3XZRB@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 4.1.2.17 1.0 ko:K01628 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R02262 1.0 RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fuculose-phosphate aldolase. L-fuculose-1-phosphate lactaldehyde-lyase. - L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLC(Carbamidomethyl)HNC(Carbamidomethyl)VAK MGYG000001300_00243;MGYG000002641_00107;MGYG000002040_01442;MGYG000002223_01488;MGYG000002274_02567 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 398815 0 472319 346797 0 297510 240072 0 272163 0 0 0 148113 0 0 0 0 0 421565 0 0 288840 0 370778 0 489009 261377 0 0 235496 241831 0 233343 0 0 0 0 575777 1204837 1030242 1164390 1099784 718658 921507 1043882 0 1372932 0 0 0 711241 0 0 0 910664 0 1164170 0 0 611239 0 831559 0 873381 786692 0 0 730913 855029 0 1032960 0 0 0 970778 789444 148579 0 141013 159541 0 0 135137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307566 0 0 0 480423 209656 0 0 357560 334084 0 0 0 0 0 0 0 434182 248355 838699 441645 556128 629878 909213 0 565334 0 0 0 736801 0 0 0 428671 0 535602 0 0 554904 0 0 0 793036 601896 0 0 696789 537730 0 758887 0 0 0 565757 697043 0 0 0 271656 120681 0 0 0 234715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 514534 0 0 0 0 0 0 255685 0 -(Gln->pyro-Glu)QLC(Carbamidomethyl)LDRDPHGNVQVSLIETEK MGYG000003697_01061;MGYG000001630_00093;MGYG000002080_02441;MGYG000002960_01607;MGYG000002293_01291 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia 0.8 976|Bacteroidetes 1.0 H 0.8 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 758656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1008728 0 0 0 0 0 0 0 0 0 379309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 864564 0 0 0 0 0 0 0 0 0 0 0 881352 0 0 0 848048 1710831 583626 0 0 0 391675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLDAYVAGLK MGYG000000251_00545 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter saccharivorans|m__MGYG000000251 1.0 COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,24AWQ@186801|Clostridia,27KF0@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Domain of unknown function (DUF3502) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF3502,SBP_bac_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 329901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLDDAYLQAR MGYG000002494_03341 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1080@1|root,COG1925@1|root,COG3412@1|root,COG1080@2|Bacteria,COG1925@2|Bacteria,COG3412@2|Bacteria,1MUT8@1224|Proteobacteria,1RRCZ@1236|Gammaproteobacteria,3WVVD@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 PEP-utilising enzyme, N-terminal 1.0 dhaM 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006476,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033554,GO:0033558,GO:0034983,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0047324,GO:0050896,GO:0051716,GO:0071704,GO:0098732,GO:0140096,GO:1901564 1.0 2.7.1.121 1.0 ko:K05881 1.0 ko00561,map00561 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000,ko02000 1.0 - 1.0 - 1.0 iECs_1301.ECs1703,iSF_1195.SF1201,iS_1188.S1285,iUTI89_1310.UTI89_C1391,iZ_1308.Z1969 1.0 EIIA-man,PEP-utilisers_N,PEP-utilizers,PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84577 0 0 140108 157245 0 0 0 0 360539 193038 197675 0 0 0 0 0 0 182537 0 0 0 0 629483 782468 978760 490406 859282 1380279 932166 458928 0 885629 0 567079 513131 715900 542728 734828 1009395 0 1356201 633369 1428664 1369378 0 1212984 1314096 543692 579005 0 1357291 1402736 0 0 1022039 588058 452765 576920 487725 786831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 130183 0 0 0 0 0 0 0 0 242963 0 97226 0 0 194304 0 0 213953 119285 0 0 0 0 0 0 0 296707 0 0 0 0 0 0 0 99071 0 0 0 0 0 0 0 0 0 0 0 259542 0 257960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 97760 0 0 -(Gln->pyro-Glu)QLDEFSQSSMAK MGYG000002517_02819 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,27NBZ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection 1.0 - 1.0 - 1.0 - 1.0 ko:K09747 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 YbaB_DNA_bd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLDESKSPSK MGYG000000251_02767;MGYG000000154_01777 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,27UW7@189330|Dorea 0.5 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 846768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLDKFK MGYG000000074_02648 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,2FTZJ@200643|Bacteroidia,22VIK@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal subunit interface protein 1.0 raiA 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 86389 0 0 0 0 0 0 93756 0 572088 0 0 0 0 0 0 0 0 0 0 96463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 679265 0 0 0 0 0 0 93636 0 754745 0 0 0 0 0 0 0 0 0 0 657785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 695370 0 0 0 0 0 0 534785 0 753529 0 0 0 0 0 0 0 0 0 0 874283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 821825 0 0 0 0 0 0 683928 0 812204 0 0 0 0 0 0 0 0 0 0 619895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1267511 0 0 0 0 0 0 1327256 0 1834692 0 0 0 0 0 0 0 0 0 0 2206595 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLDNEIIETGKR MGYG000002293_00334;MGYG000003697_01647 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 D 1.0 Endoribonuclease that initiates mRNA decay 1.0 rny 1.0 - 1.0 - 1.0 ko:K18682 1.0 ko03018,map03018 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03019 1.0 - 1.0 - 1.0 - 1.0 DUF3552,HD,KH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLDPLVVGQEHYDTAR MGYG000002534_04897;MGYG000002323_04215;MGYG000003390_00723;MGYG000000093_05344;MGYG000002515_03903;MGYG000002506_03402;MGYG000002494_02404;MGYG000002366_00010;MGYG000002507_04224 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,3XPEM@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 477726 612273 337057 1155570 424820 672478 420832 488661 536968 545674 569154 485499 324119 883325 341360 578620 427362 0 0 351701 360116 520146 0 395474 382501 793101 513280 0 489169 309955 807365 317090 371755 493178 358229 887170 693675 780301 1106969 1583407 1681770 1786137 1513280 2463870 1655629 1100800 1686357 1992626 859598 1798832 1089435 1635892 1176658 1500304 2229322 0 0 1399486 1678749 2744325 0 3151173 1796181 1333054 1644631 0 1973139 2279456 1321034 1514872 1723393 1466296 1042701 1492931 1771723 1347168 457568 595729 642245 790575 369408 1101815 415274 570634 714379 458878 397723 385460 443710 480144 557670 437571 478501 0 0 612607 470282 813244 0 850490 492177 668368 601685 0 617426 529666 434240 383072 527695 718549 683446 524995 601763 718859 1152334 913697 736930 854247 870622 1192351 1611466 1362479 782344 1072408 459978 722195 693315 884688 823521 714023 943170 0 0 864244 1074348 1255916 0 1046666 1284306 1272711 1098474 0 931692 1055499 478802 811283 872106 1353794 1398723 1327507 689567 910313 0 0 0 512688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 619645 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLDYAEAGDNAGVLLR MGYG000002925_00238 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__RF39|f__UBA660|g__CAG-877|s__CAG-877 sp900548695|m__MGYG000002925 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,3VNVP@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444387 0 0 0 0 324572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLEAATQSEGK MGYG000002494_04638 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,3XN3I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 1.0 - 1.0 ko:K03695 1.0 ko04213,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - multiple species 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 357065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLEAEETTK MGYG000003366_00226;MGYG000002963_04226;MGYG000000133_00303;MGYG000000201_03111;MGYG000001310_00228;MGYG000002670_02305;MGYG000001777_01222;MGYG000000171_02644;MGYG000003063_01532;MGYG000000268_00625;MGYG000000249_01189;MGYG000001615_01162;MGYG000000806_01491;MGYG000002492_02076;MGYG000000136_00457;MGYG000000067_00824;MGYG000000095_04662;MGYG000002602_00510;MGYG000004210_00553;MGYG000002298_01718;MGYG000000181_01147;MGYG000000489_01319;MGYG000001374_02751;MGYG000004764_00051;MGYG000000212_00037;MGYG000000252_03028;MGYG000004697_00536 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3Y05R@572511|Blautia 0.25925925925925924 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 264320 367207 0 553925 0 0 0 0 386550 0 170061 351892 0 0 0 208857 0 0 0 815974 520445 585760 224972 0 378428 639738 0 0 0 0 312406 0 0 118895 0 369034 0 0 399545 314420 0 173179 0 0 0 0 123357 0 279398 0 0 0 0 649036 0 0 0 0 1078224 0 0 0 174852 1130404 0 0 0 0 130265 0 0 0 0 0 0 0 720861 0 0 467199 317247 0 0 0 348737 0 0 312713 0 0 0 918716 0 0 0 395974 906273 158659 229500 0 349491 973634 0 0 0 0 460601 0 0 252358 0 510537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1307859 2609479 0 1501935 1743225 0 0 0 1801871 0 1749347 1871539 0 0 0 544684 0 0 0 1701614 583453 1295578 1517380 0 1779886 670311 0 0 0 0 2435272 0 0 1505280 0 1134364 -(Gln->pyro-Glu)QLEAEGKPAQIIEK MGYG000002485_02451;MGYG000004828_01990 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0264@1|root,COG0264@2|Bacteria,378TR@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 504849 0 0 0 1075786 0 0 0 0 0 0 0 0 0 0 0 655828 0 453067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLEAETTTK MGYG000002528_02458;MGYG000000080_01155 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1976330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLEAYLGVK MGYG000000177_00608 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,36FZP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 2-hydroxyglutaryl-CoA dehydratase, D-component 1.0 - 1.0 - 1.0 1.3.7.8,4.2.1.54 1.0 ko:K04112,ko:K20627 1.0 ko00362,ko00640,ko00643,ko01100,ko01120,ko01220,map00362,map00640,map00643,map01100,map01120,map01220 1.0 M00541 1.0 R02451,R02963 1.0 RC00002,RC00818,RC01839 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HGD-D 1.0 - 1.0 - 1.0 - 1.0 - 1.0 benzoyl-CoA reductase. | lactoyl-CoA dehydratase. - Inactive toward aromatic acids that are not CoA esters but will also catalyze the reaction: NH3 + acceptor + 2 ADP + 2 phosphate = hydroxylamine + reduced acceptor + 2 ATP + H2O.-!-In the presence of reduced acceptor, but in the absence of oxidizable substrate, the enzyme catalyzes the hydrolysis of ATP to ADP plus phosphate.-!-Formerly EC 1.3.99.15. | A bacterial enzyme that is involved in propanoate fermentation (also known as the acrylate pathway). 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized 2[4Fe-4S]- [ferredoxin] + 2 phosphate = 2 ATP + benzoyl-CoA + 2 H2O + reduced 2[4Fe- 4S]-[ferredoxin]. | (R)-lactoyl-CoA = acryloyl-CoA + H2O. 1.0 1.0 1.0 1.0 Benzoate degradation;Metabolic pathways;Styrene degradation;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 256296 0 0 0 171958 0 0 0 0 0 0 0 0 0 0 0 0 284724 0 441342 362320 0 131295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144563 0 0 0 109125 0 0 0 0 0 0 0 0 0 0 0 0 224404 0 96871 60219 0 80045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81460 0 0 182172 0 61045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLEDAVGKEEAK MGYG000001489_02765;MGYG000002218_01253;MGYG000002438_00429 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,22VVH@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382718 0 314786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527791 0 0 0 0 0 0 0 0 620641 0 0 0 0 0 0 0 0 137019 0 387430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559939 0 0 0 0 0 0 0 0 788785 0 0 0 0 0 0 0 0 661963 0 878527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470629 0 0 0 0 0 0 0 0 854457 0 0 0 0 0 0 0 0 623582 0 215042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1244083 0 0 0 0 0 0 0 0 1467185 0 0 0 0 0 0 0 0 1709091 0 967274 0 0 0 0 0 0 -(Gln->pyro-Glu)QLEDGLTEKK MGYG000000105_02189;MGYG000001346_03530;MGYG000003681_00297;MGYG000001313_01991 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,2FN0C@200643|Bacteroidia,4AKKG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG19144 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 699987 0 0 0 0 597257 0 0 0 0 407169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 954173 0 0 0 0 200030 0 0 0 0 759868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 940839 0 0 0 0 1071662 0 0 0 0 1273582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1058004 0 0 0 0 451135 0 0 0 0 1355583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409798 0 0 0 0 329170 0 0 0 0 355319 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLEDVC(Carbamidomethyl)GKPFDYDKFVK MGYG000000420_01196 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900553995|m__MGYG000000420 1.0 COG1775@1|root,COG1775@2|Bacteria,37BRW@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 E 1.0 2-hydroxyglutaryl-CoA dehydratase, D-component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HGD-D 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 204309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244250 0 326958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 890272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521643 0 774735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLEEAGAEVELK MGYG000000053_00901;MGYG000000044_01728;MGYG000000183_03084;MGYG000003202_00136;MGYG000004468_00169;MGYG000001562_01082;MGYG000002082_01855;MGYG000003701_03116;MGYG000003279_00958;MGYG000000825_01460;MGYG000004006_00426;MGYG000003282_01991;MGYG000004830_01657;MGYG000001546_01548;MGYG000004469_00969;MGYG000002867_00700;MGYG000001655_02927;MGYG000001608_02199;MGYG000002007_00362;MGYG000001489_05034;MGYG000000003_02516;MGYG000000138_00672;MGYG000002438_02328;MGYG000000117_01470;MGYG000002033_01014;MGYG000004573_00011;MGYG000003172_00544;MGYG000002203_00881;MGYG000000254_02576;MGYG000000074_01766;MGYG000000144_02611;MGYG000003498_00517;MGYG000004711_00303;MGYG000000222_01120;MGYG000001552_00977;MGYG000004658_01198;MGYG000002556_01325 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 0.43243243243243246 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 0.972972972972973 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 237460 425548 0 0 737535 0 0 858219 569803 326847 738785 447873 0 383955 527121 0 0 0 0 581150 407889 0 412785 0 0 0 0 0 0 477833 626670 411418 291319 564689 0 0 415671 0 0 426622 0 834284 564514 0 0 0 421466 471940 755547 122108 0 280360 499519 0 0 0 0 920028 327357 0 128369 0 0 0 0 380543 556501 134649 320896 261625 0 271729 0 0 0 0 0 0 0 334256 369907 0 0 401271 564752 358244 865331 489757 0 922881 0 0 0 0 0 382382 0 0 819738 0 0 0 0 0 541752 430029 365243 391620 0 491272 0 0 765080 0 458493 664546 0 382981 628170 0 0 1126263 5921510 387778 3698569 0 0 1013992 551055 0 0 0 0 2368998 503118 0 489701 0 0 0 0 638087 5353179 734185 534412 593213 887088 6692063 0 0 897798 0 920878 470296 0 1834147 602512 0 0 781720 707171 1009177 1223284 1111398 0 541665 985360 0 0 0 0 1365208 941529 0 609366 0 0 0 0 942769 1626032 562100 1496289 238199 780002 1273483 0 0 490066 -(Gln->pyro-Glu)QLEIEREAIKR MGYG000003282_00225;MGYG000004757_00271;MGYG000001372_02360;MGYG000004885_00467;MGYG000002478_04149;MGYG000004464_01783;MGYG000000243_01129;MGYG000004797_00905;MGYG000004763_00452;MGYG000000196_01208 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,2FM5N@200643|Bacteroidia,4AKZF@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 - 1.0 - 1.0 ko:K03695 1.0 ko04213,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - multiple species 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLEKNPWDEYETIYTPGSVHK MGYG000003697_01824;MGYG000002080_02027 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 634229 416498 315547 0 305735 124621 0 435071 0 0 541491 365722 0 0 325404 223011 0 267308 0 0 0 340357 336424 448939 0 497403 0 310592 0 0 410595 362388 248234 0 0 0 470858 414822 387106 306770 262559 0 409189 392738 0 325499 0 0 425694 405475 273070 0 462134 442248 0 499512 0 0 0 364793 0 124541 0 538908 0 216061 0 0 285993 293753 324740 0 0 0 240823 331969 204856 0 0 0 125693 458488 0 162160 0 0 371977 374056 238940 0 0 209366 0 329747 0 0 0 190415 201074 296721 0 261783 0 164816 0 0 507523 0 271166 0 0 0 0 320505 543529 760475 2143808 0 1450622 2062416 0 782906 0 0 2191551 722113 1455361 0 1003068 1334316 0 919706 0 0 0 2064317 1526906 1504156 0 565651 0 1416852 0 0 1107755 938149 1348370 0 0 0 553649 1432758 0 0 0 0 322929 342180 0 0 0 0 330709 245330 222750 0 0 236663 0 160545 0 0 0 397742 455004 519116 0 360563 0 581188 0 0 0 257641 231859 0 0 0 0 245038 -(Gln->pyro-Glu)QLEQEQMK MGYG000002323_03125;MGYG000002477_01825;MGYG000002513_01534;MGYG000002494_04624;MGYG000001465_01866;MGYG000003360_03259;MGYG000000337_01318;MGYG000002535_00930;MGYG000002504_03064;MGYG000003883_03143;MGYG000002506_02124;MGYG000002515_00446;MGYG000002525_00836;MGYG000003372_01568;MGYG000000093_05408 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1Y8KB@135625|Pasteurellales 0.7333333333333333 135625|Pasteurellales 0.7333333333333333 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 0.7333333333333333 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 572785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 707710 0 496575 0 0 0 0 0 0 0 0 404207 0 0 0 0 0 0 0 765396 0 0 1206804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1295459 0 931687 0 0 0 0 0 0 0 0 684010 0 0 0 0 485902 0 0 509222 0 0 637833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211002 0 608305 0 0 0 0 0 0 0 0 234440 0 0 0 0 169434 0 0 516198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401010 0 896411 0 0 0 0 0 0 0 0 824579 0 0 0 0 380334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLESDIYNAIHR MGYG000002281_02975;MGYG000000196_02928 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 2FJH4@1|root,312SQ@2|Bacteria,4PHR0@976|Bacteroidetes,2FTF5@200643|Bacteroidia,4ARNA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 YtxH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 616143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLFGESEGKDNK MGYG000002040_00814;MGYG000003291_01409;MGYG000002224_00441;MGYG000001319_00092;MGYG000001300_02540;MGYG000000039_01586;MGYG000001255_00391;MGYG000003899_00328;MGYG000003166_01024;MGYG000000022_00661;MGYG000000195_00211;MGYG000004679_00057;MGYG000000089_01040 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WHJX@541000|Ruminococcaceae 0.9230769230769231 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 0.9230769230769231 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 800632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507849 0 0 0 0 843048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1788125 0 0 0 0 1039423 0 0 0 0 1766897 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLFKDEVR MGYG000004552_02371;MGYG000000650_02217;MGYG000001780_04179;MGYG000001615_05534;MGYG000000029_03508;MGYG000000121_02100;MGYG000002478_04002;MGYG000004735_00074;MGYG000000174_03354;MGYG000000138_02270;MGYG000000098_03146;MGYG000001374_02303;MGYG000001346_03291;MGYG000002218_01878;MGYG000000013_02510;MGYG000002685_01245;MGYG000004769_01556;MGYG000002438_02747;MGYG000004899_02570;MGYG000003351_04375;MGYG000001493_04160;MGYG000000198_03851;MGYG000000044_00075;MGYG000002455_02568;MGYG000001617_00853;MGYG000000133_02443;MGYG000000179_04192;MGYG000001345_00044;MGYG000000222_01345 domain d__Bacteria 1.0 COG0519@1|root,COG0519@2|Bacteria,4NZSX@976|Bacteroidetes,2FNJE@200643|Bacteroidia,4AMZI@815|Bacteroidaceae 0.5517241379310345 976|Bacteroidetes 0.5517241379310345 F 1.0 Psort location Cytoplasmic, score 0.5517241379310345 - 1.0 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 0.5517241379310345 6.3.5.2 1.0 ko:K01951 1.0 ko00230,ko00983,ko01100,map00230,map00983,map01100 1.0 M00050 1.0 R01230,R01231,R08244 1.0 RC00010,RC00204 1.0 ko00000,ko00001,ko00002,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 GATase,GMP_synt_C,NAD_synthase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GMP synthase (glutamine-hydrolyzing). GMP synthetase (glutamine-hydrolyzing). Involved in the de novo biosynthesis of guanosine nucleotides.-!-An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain.-!-The enzyme can catalyze the second reaction alone in the presence of ammonia.-!-Formerly EC 6.3.4.1. ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate. 1.0 1.0 1.0 1.0 Purine metabolism;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 662381 676092 814647 0 838677 823317 0 0 0 0 801212 0 919731 809433 0 0 933298 539804 0 0 771556 589176 589882 695691 0 738381 0 501749 0 0 0 0 579680 0 0 0 553494 618632 0 498216 663314 0 808766 544052 0 0 0 0 1047860 0 1686057 662865 0 0 617576 234787 0 0 745888 574960 392707 377283 0 591895 0 295171 0 0 0 0 710678 0 0 0 656123 1295850 520380 683909 1058457 0 820048 1124406 0 0 0 0 0 0 739562 1340278 0 0 1316098 700424 0 0 827891 738251 1200572 1258707 0 584672 0 744184 0 0 0 0 445914 0 0 0 837033 835751 455674 1293306 1165651 0 352939 1214026 0 0 0 0 1139765 0 1648590 1149616 0 0 1378665 3332145 0 0 1969941 700510 1356525 1456133 0 782820 0 965100 0 0 0 0 1765766 0 0 0 648496 1156982 1407314 1333922 679152 0 2468113 2439210 0 0 0 0 1580146 0 2000881 837193 0 0 2317527 12565386 0 0 1175387 2240695 1081187 2916598 0 899114 0 0 0 0 0 0 1407548 0 0 0 1761216 1445527 -(Gln->pyro-Glu)QLGAIHR MGYG000002478_02225;MGYG000000243_00756;MGYG000004797_02333 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,2FPF1@200643|Bacteroidia,4AMCM@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 pheB 1.0 - 1.0 5.4.99.5 1.0 ko:K04516 1.0 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 1.0 M00024,M00025 1.0 R01715 1.0 RC03116 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CM_2,DAHP_synth_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 chorismate mutase. hydroxyphenylpyruvate synthase. - chorismate = prephenate. 1.0 1.0 1.0 1.0 Biosynthesis of amino acids;Metabolic pathways;Biosynthesis of secondary metabolites;Phenylalanine, tyrosine and tryptophan biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLGALVYSLHK MGYG000003937_00998;MGYG000004866_01442;MGYG000000724_00536;MGYG000000084_02378;MGYG000001157_00384;MGYG000003921_00769;MGYG000002059_00009 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 2ET0Z@1|root,33KJ7@2|Bacteria,1VNW5@1239|Firmicutes,254DV@186801|Clostridia,3WQEJ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-ribbon_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 211763 0 0 0 0 0 228811 0 0 0 0 256676 0 0 0 0 0 0 342258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 765455 0 0 0 0 0 227847 0 0 0 0 352938 0 0 0 0 272862 0 665937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265150 0 0 0 0 0 109833 0 0 0 0 0 0 0 0 0 137806 0 173307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476543 0 0 0 0 0 752932 0 0 0 0 687389 0 0 0 0 2352346 0 549365 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLGEDPWVAIAKR MGYG000002534_01740;MGYG000000093_01905;MGYG000002515_01006;MGYG000002535_02781;MGYG000002477_03740;MGYG000002506_00237;MGYG000002494_01406;MGYG000002323_01525 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,3Z8AH@586|Providencia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2401767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLGFDAIHDTVHEM(Oxidation)AKDEAR MGYG000004828_01486;MGYG000004893_01870;MGYG000002485_00254 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG1592@1|root,COG1592@2|Bacteria,378I0@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 523782 0 0 0 370038 0 0 0 0 0 0 0 0 0 0 0 513669 0 378506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLGFDAIHDTVHEMAK MGYG000004893_01870;MGYG000002485_00254 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG1592@1|root,COG1592@2|Bacteria,378I0@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 499659 0 0 642902 0 0 0 513361 213987 0 0 0 0 634123 0 0 0 0 0 625063 0 471046 0 0 0 0 0 0 0 0 431198 0 0 0 0 232216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLGFDAIHDTVHEMAKDEAR MGYG000004828_01486;MGYG000004893_01870;MGYG000002485_00254 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG1592@1|root,COG1592@2|Bacteria,378I0@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 145171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63420 0 0 0 0 0 0 0 598046 0 0 1614707 0 0 0 1034020 815965 332623 586955 0 0 1467472 1015086 0 0 0 0 1387139 0 809546 0 0 367793 0 0 0 736317 525215 481084 0 0 0 0 477160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLGHDVTIYEAMPK MGYG000000133_01493 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WCXB@538999|Clostridiales incertae sedis 1.0 186801|Clostridia 1.0 C 1.0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 1.0 - 1.0 - 1.0 1.17.1.9,1.3.1.1 1.0 ko:K00123,ko:K17722 1.0 ko00240,ko00410,ko00630,ko00680,ko00770,ko01100,ko01120,ko01200,map00240,map00410,map00630,map00680,map00770,map01100,map01120,map01200 1.0 M00046 1.0 R00519,R00977,R01414,R11026 1.0 RC00072,RC00123,RC02796 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_6,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,NAD_binding_1,NAD_binding_8,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate dehydrogenase. | dihydrouracil dehydrogenase (NAD(+)). NAD(+)-formate dehydrogenase. The enzyme from most aerobic organisms is devoid of redox-active centers but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centers, flavin and a molybdenum center.-!-Together with EC 1.12.1.2, forms a system previously known as formate hydrogenlyase.-!-Formerly EC 1.2.1.2. | The enzyme was originally discovered in the uracil-fermenting bacterium, Clostridium uracilicum, which utilizes uracil and thymine as nitrogen and carbon sources for growth.-!-Since then the enzyme was found in additional organisms including Alcaligenes eutrophus, Pseudomonas strains and Escherichia coli. formate + NAD(+) = CO2 + NADH. | (1) 5,6-dihydrouracil + NAD(+) = H(+) + NADH + uracil. (2) 5,6-dihydrothymine + NAD(+) = H(+) + NADH + thymine. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;beta-Alanine metabolism;Microbial metabolism in diverse environments;Pantothenate and CoA biosynthesis;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 813401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLGIDPAELGYSSKK MGYG000001636_00136;MGYG000003266_00909;MGYG000002050_01081;MGYG000001718_00229;MGYG000002970_01274;MGYG000002775_00112 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CUFQ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 - 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLGITTGAQAK MGYG000000356_01643;MGYG000000389_01367;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 5047509 2681990 2681943 8435829 3161624 3866282 4753950 4888230 5043829 6209966 3473304 6853979 3840799 5180466 6304334 3491081 6233179 0 6557443 4864801 6054437 3986651 0 5317481 4710913 5646486 6751651 0 581428 6398966 2579172 2072341 2870593 6541602 4903345 5290305 5776432 1953244 0 0 0 103232 342140 384240 0 209866 323486 328365 352532 0 240249 588046 0 408058 384612 0 272767 173132 292171 0 0 187688 198616 0 252198 0 0 514646 91879 0 0 448055 0 190343 0 193658 2521118 635498 626321 1979093 1543634 1056503 2197304 2729254 3378344 1937448 2677645 3825117 2080562 3006039 2624362 1681129 1737691 0 1917013 2120370 1426861 0 0 0 3233678 3301924 2679175 0 669305 2751623 562624 0 709668 1564316 2832979 3053681 3437405 730980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17753541 10240148 17779326 6572921 25123271 24906230 10839542 11847431 20676229 23520384 16524060 17014857 19355567 12395590 24847469 12773123 19362498 0 18366869 16036698 11173507 13754269 0 23246244 21385125 18755177 14737758 0 4440428 19789156 14392721 6795971 11422907 17561743 16835225 15864405 29373351 19370065 -(Gln->pyro-Glu)QLGITTGQQAK MGYG000004271_01770;MGYG000000271_01499 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3759680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 393695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLGKDVIVDGVNKR MGYG000002528_01293;MGYG000000028_01644 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,25VI8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 2.2.1.2,5.3.1.9 1.0 ko:K01810,ko:K13810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00004,M00007,M00114 1.0 R01827,R02739,R02740,R03321 1.0 RC00376,RC00439,RC00563,RC00604 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. | glucose-6-phosphate isomerase. glycerone transferase. | phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187074 0 0 95479 0 0 0 0 0 0 0 438152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312039 0 0 0 0 0 0 0 87506 0 0 0 0 0 0 0 1328237 0 0 0 473748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025835 0 398638 0 0 0 0 881341 0 0 1121166 0 0 0 0 0 0 0 265917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 627490 0 0 228181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLGNDVVVDGVNKR MGYG000000262_02071 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,25VI8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 2.2.1.2,5.3.1.9 1.0 ko:K01810,ko:K13810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00004,M00007,M00114 1.0 R01827,R02739,R02740,R03321 1.0 RC00376,RC00439,RC00563,RC00604 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. | glucose-6-phosphate isomerase. glycerone transferase. | phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 793717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLGPVTKPM(Oxidation)PEWK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 453601 196132 0 0 375003 0 0 0 244831 0 0 365343 0 439220 676789 296940 0 257408 0 0 738435 0 0 0 0 0 0 0 0 0 312700 0 0 311174 0 0 0 156156 419088 0 247064 0 0 430775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 583678 0 0 165493 0 0 294853 0 1399015 2842631 234611 1951061 0 1705232 393551 1278693 0 1294426 370544 0 1177735 1037284 1572337 1146491 1114499 0 1837636 1695580 958619 1798193 0 981103 1496393 1447432 1949898 0 0 988478 270724 1373644 715562 1529436 1615009 0 1186931 0 662356 862842 511005 863341 0 995411 1059252 640160 0 1649559 486678 0 1091173 895828 436660 1272747 982624 0 476336 1300595 652492 1092872 0 1086181 677584 251338 567854 0 0 743515 637145 542020 774963 422145 659702 0 361206 424668 353695 718318 837994 568036 0 619450 446179 462310 0 553991 864547 0 906153 525759 558139 833950 448867 0 586881 420003 330708 662414 0 489818 491091 537899 698626 0 0 364300 949777 839205 966202 725700 334997 0 837201 882232 -(Gln->pyro-Glu)QLGPVTKPMPEWK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 2362496 7024492 3569426 1082066 5504521 3824383 842144 4043044 1308150 3656282 2462552 3303216 5681737 1936518 3089967 4050986 1932168 0 3218609 3003900 2013911 4517448 0 1434226 3673290 1887562 2272090 0 1727906 1874745 1713347 4705674 1781935 2106689 2480635 1170309 1404655 2104692 7009771 6163027 1770746 4423310 2156261 4087961 13691438 5251512 4566121 3456940 2124434 3148768 3188120 3281546 3871717 1800105 3201053 0 5828207 7551381 4334158 3148833 0 8166936 4888513 6137554 6642473 0 8318249 3816863 5024516 3662834 1666144 6100987 5047032 7365319 4812321 1742662 15230091 16250424 3602510 18505325 2256665 15295529 3634104 14233988 4566371 13063682 4800545 9675142 11890818 9870113 20016472 12208949 12975970 0 20438570 17411305 12411782 22209770 0 7982668 18800337 15977021 20435822 0 2795450 10509395 3823473 12821648 8612544 21856814 19366070 4761068 12826127 3259875 6504139 10023457 4401597 9656709 6610808 12641788 12801391 7673380 5978184 17356296 6060544 3364182 11813460 7426321 6637142 14975212 11729787 0 4350046 11144903 5650761 10465932 0 10635658 6697249 3427781 8000157 0 9684887 8021260 4739242 5772087 6889856 4056835 7001610 4417096 3341659 6136353 5338033 9195949 10675143 6374842 13804040 6182627 3739249 5338166 5738525 7673668 9047061 6096987 12185979 4367931 8178946 10862360 7560375 0 7848216 6443334 5726118 8103441 0 4960320 5731420 5976516 6987306 0 2434443 8004038 12877813 11249016 14144741 9245559 7488861 5346975 8155813 10867325 -(Gln->pyro-Glu)QLGSDFPSDPVEQLK MGYG000000089_02490 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLHFGVR MGYG000003683_00463;MGYG000002469_01094;MGYG000001292_01123 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Belongs to the transketolase family 1.0 tkt 1.0 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA,Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 161840 0 370902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 266913 0 0 0 0 0 0 0 78545 0 131518 0 0 0 0 176800 0 0 0 79184 263585 637458 705326 890615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3046327 0 0 0 0 1197242 0 0 523069 0 2441593 0 0 1565617 0 652184 0 0 0 588893 1042587 456372 534652 572263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230585 0 0 0 0 0 0 0 530320 0 393857 0 0 0 0 910571 0 0 0 398898 410754 191568 349458 280246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242996 0 0 0 0 0 0 0 91359 0 586489 0 0 801238 0 356659 0 0 0 144569 279339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 51362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53911 0 -(Gln->pyro-Glu)QLHTAETEK MGYG000003697_01373;MGYG000002050_01273 domain d__Bacteria 1.0 COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,2FMVJ@200643|Bacteroidia 0.5 976|Bacteroidetes 0.5 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 - 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DUF1398,Metalloenzyme,PglZ,Phosphodiest,iPGM_N 0.5 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7516624 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLHVGQEEADPVTGAR MGYG000002517_01802 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 O-acetylhomoserine 1.0 metY 1.0 - 1.0 2.5.1.49 1.0 ko:K01740 1.0 ko00270,ko01100,map00270,map01100 1.0 - 1.0 R01287,R04859 1.0 RC00020,RC02821,RC02848 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism;Metabolic pathways 1.0 none 1.0 493262 0 0 302146 0 0 0 0 0 0 0 0 0 0 284582 0 0 0 0 402268 0 0 0 0 336404 218369 335109 0 0 494933 0 0 0 0 406153 479073 426943 0 464469 0 0 249673 0 0 0 0 0 0 0 0 0 0 438635 0 0 0 0 356588 0 0 0 0 455955 678139 468946 0 0 489042 0 0 0 0 566833 481613 364778 0 276237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337347 0 0 1510958 0 0 2452608 0 0 0 0 0 0 0 0 0 0 1652410 0 0 0 0 706837 0 0 0 0 1468542 1061134 1952342 0 0 1424280 0 0 0 0 1025861 1670921 890553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLIAGAEPMVR MGYG000000133_01657 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes,257WP@186801|Clostridia,3Y0N6@572511|Blautia 1.0 186801|Clostridia 1.0 K 1.0 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits 1.0 rpoZ 1.0 - 1.0 2.7.7.6 1.0 ko:K03060 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 503312 0 0 0 0 0 -(Gln->pyro-Glu)QLIAQSWHTDEIRK MGYG000002494_01897;MGYG000002515_03682 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,3X00P@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle 1.0 ppc 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.0 4.1.1.31 1.0 ko:K01595 1.0 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 1.0 M00168,M00170,M00171,M00172,M00173,M00346,M00374 1.0 R00345 1.0 RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iSFV_1184.SFV_4025 1.0 PEPcase,PEPcase_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxylase. phosphoenolpyruvic carboxylase. This enzyme replenishes oxaloacetate in the tricarboxylic acid cycle when operating in the reverse direction.-!-The reaction proceeds in two steps: formation of carboxyphosphate and the enolate form of pyruvate, followed by carboxylation of the enolate and release of phosphate. oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 162936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179315 0 181031 0 0 0 0 0 0 0 0 185319 0 0 0 0 161963 0 358115 773784 0 0 1728067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1463925 0 1039268 0 0 0 0 0 0 0 0 306302 0 0 0 0 302000 0 289441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107167 0 344240 0 0 0 0 0 0 0 0 0 0 0 0 0 257343 0 344955 258002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181350 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92487 0 0 0 0 0 -(Gln->pyro-Glu)QLIAYDALNR MGYG000004757_00444 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__UBA6398|s__UBA6398 sp900555645|m__MGYG000004757 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1589164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLIDAVIGR MGYG000001787_02109;MGYG000001306_03249;MGYG000001599_00729;MGYG000000273_01081;MGYG000002478_04323;MGYG000003420_00356;MGYG000000042_02614;MGYG000000243_00993;MGYG000001925_01151;MGYG000001364_01802;MGYG000000781_01397;MGYG000003693_02828 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4656@1|root,COG4656@2|Bacteria,4NIS7@976|Bacteroidetes,2FMAQ@200643|Bacteroidia,4AM9Y@815|Bacteroidaceae 0.9166666666666666 976|Bacteroidetes 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4_10,Fer4_17,Fer4_7,Fer4_8,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56169 0 0 0 0 123641 0 0 0 0 68667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180256 0 0 0 0 290925 0 0 0 0 276020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67066 0 0 0 0 133787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLIEC(Carbamidomethyl)LQPNRR MGYG000003022_01750;MGYG000003352_01361 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,1KIWG@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 M 1.0 Belongs to the ompA family 1.0 ompA 1.0 - 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 - 1.0 DUF1134,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1920377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2320097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLIYTAR MGYG000000127_04024;MGYG000000262_02232;MGYG000000077_02465;MGYG000001707_00050 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,36EDS@31979|Clostridiaceae 0.5 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 1.0 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLKAEEILPR MGYG000001415_00421;MGYG000003279_00276;MGYG000004756_00243;MGYG000001302.1_01584;MGYG000004536_01290;MGYG000000003_01073 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,4PKTH@976|Bacteroidetes,2G35Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Conserved carboxylase domain 1.0 - 1.0 - 1.0 4.1.1.3,6.4.1.1 1.0 ko:K01571,ko:K01960 1.0 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 1.0 M00173,M00620 1.0 R00217,R00344 1.0 RC00040,RC00367 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 Biotin_lipoyl,Biotin_lipoyl_2,HMGL-like,OAD_gamma,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | pyruvate carboxylase. | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). pyruvic carboxylase. | oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The animal enzyme requires acetyl-CoA. | The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. ATP + hydrogencarbonate + pyruvate = ADP + H(+) + oxaloacetate + phosphate. | H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 541424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324658 0 421572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLKAEVPEFR MGYG000000133_01766;MGYG000000271_00796 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,3Y019@572511|Blautia 0.5 186801|Clostridia 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 - 1.0 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLKQDPWETIEEKYPVGSK MGYG000004797_04001;MGYG000000196_00547;MGYG000001378_02385;MGYG000002281_02540;MGYG000002455_03377;MGYG000000243_01228;MGYG000002478_02960 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 3051290 2534350 5125146 2296873 3925746 2342427 2882963 2725733 3080810 3809195 3365922 2802251 5110706 3739307 2776799 4383169 2539583 1396910 3025222 2614305 2630153 2012267 1544129 3096876 3132567 3402361 3510370 805308 2718121 3712457 3842764 4029305 4769257 2992911 2885782 3011211 2820688 4791038 2114350 1150788 1842222 2262434 2840515 2126429 2111374 2447261 1842330 2955437 3466976 2347965 4656552 2361412 2388678 3895527 2328214 569320 2684657 1686753 2183744 2186696 899357 1658097 2457423 2537562 2058538 955953 2753509 3001515 1301182 2180658 1644516 2135273 2556045 1956020 2229379 1547265 1636612 788787 1725806 1451113 2612475 1635541 1477552 1521573 1585462 1446876 1721935 1733544 3233385 1541384 1384834 2291203 1250464 2000413 1392182 1330743 1263083 1176708 1596909 1480142 1303675 1604799 1227889 1423410 1297955 1301757 1578872 989653 1478320 1659967 1486050 1829014 1343692 1620745 836736 856411 1203116 912772 1062272 1071834 918896 1090127 1031988 1140952 1573486 1260566 1827066 959306 885011 1402911 1020182 818190 1089206 924245 1352126 1065222 1295683 973123 1254012 1152404 1229757 899323 969965 1064966 837266 1567582 1092734 1113322 1294211 1320891 1358840 1211750 1546605 1497460 1174268 286711 2843124 1766323 1874957 1677545 1763837 1168181 1763733 1597997 5687378 1147811 1733761 3214082 1922595 1863304 1738880 1880559 1618892 2104288 1743003 1763904 1847139 2308625 1797545 2195463 1721213 2380000 1509566 1708433 1043859 2785807 2497058 1385188 2053454 1610290 -(Gln->pyro-Glu)QLKTPEEVAR MGYG000000184_01189;MGYG000004296_00406;MGYG000001338_02790 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 913535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1144499 0 0 0 0 0 0 0 810118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382292 0 0 0 0 0 0 0 1672450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1107214 0 0 0 0 0 0 0 1543291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 855298 0 0 0 0 0 0 0 1025647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248957 0 0 0 0 0 0 -(Gln->pyro-Glu)QLLASGVGQTSR MGYG000002478_01914;MGYG000002281_00881;MGYG000004876_02356;MGYG000003312_02923;MGYG000000196_00013;MGYG000001787_00420;MGYG000003202_01366;MGYG000002561_01112;MGYG000000013_00011;MGYG000004019_02126;MGYG000001346_03669;MGYG000000224_02757;MGYG000003221_01732;MGYG000002455_04536;MGYG000003252_06179;MGYG000002120_00051;MGYG000000243_02236;MGYG000002171_02209;MGYG000004763_02744;MGYG000001370_01226 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,2FN3G@200643|Bacteroidia,4AK6B@815|Bacteroidaceae 0.85 976|Bacteroidetes 1.0 F 1.0 bifunctional purine biosynthesis protein PurH 0.85 purH 1.0 - 1.0 2.1.2.3,3.5.4.10 1.0 ko:K00602 1.0 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 1.0 M00048 1.0 R01127,R04560 1.0 RC00026,RC00263,RC00456 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 AICARFT_IMPCHas,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylaminoimidazolecarboxamide formyltransferase. | IMP cyclohydrolase. aminoimidazolecarboxamide ribonucleotide transformylase. | inosinicase. - (6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. | H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. 1.0 1.0 1.0 1.0 Antifolate resistance;Metabolic pathways;One carbon pool by folate;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 130469 0 262469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 806907 0 568903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294605 0 344082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575220 0 215942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450123 0 438726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLLEAEGKYDIK MGYG000003697_01280;MGYG000002293_01727 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,2FSGZ@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 1.0 rpsI 1.0 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1643413 0 0 0 0 2302397 0 0 0 0 1724675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150942 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLLEAGVHFGHQTR MGYG000000022_01263;MGYG000000150_02990;MGYG000000067_03067;MGYG000004221_00411;MGYG000004252_01040;MGYG000002610_00266;MGYG000001675_01243;MGYG000000280_00470;MGYG000000080_02857;MGYG000002098_01442;MGYG000001185_00083;MGYG000003695_01035;MGYG000002788_00212;MGYG000001444_00261;MGYG000002517_01401;MGYG000000404_00635;MGYG000001315_00796;MGYG000002274_00630;MGYG000004788_00490;MGYG000001564_00846;MGYG000003133_02718;MGYG000000417_00486;MGYG000000141_02711;MGYG000002224_00296;MGYG000000743_01190;MGYG000004735_00874;MGYG000000278_03745;MGYG000000136_00722;MGYG000004727_01767;MGYG000000214_00298;MGYG000001319_00659;MGYG000000392_00214;MGYG000002530_00769;MGYG000004628_02226;MGYG000000089_01181;MGYG000002993_00244;MGYG000001470_02362;MGYG000002492_01612;MGYG000000163_01035;MGYG000002272_01435;MGYG000003939_00421;MGYG000000201_03495;MGYG000000073_00924;MGYG000002994_00756;MGYG000001627_01481;MGYG000000213_00523;MGYG000004769_00832;MGYG000000071_00548;MGYG000003504_00560;MGYG000002121_00509;MGYG000002212_02444;MGYG000000195_01345;MGYG000000255_00471;MGYG000000271_00181;MGYG000001477_01559;MGYG000000002_01239;MGYG000003210_01100;MGYG000001646_00858;MGYG000002042_01031;MGYG000001651_01608;MGYG000000733_01113;MGYG000002702_01822;MGYG000001027_00474;MGYG000001615_00539;MGYG000001577_01277;MGYG000001658_01304;MGYG000000370_00988;MGYG000002975_00796;MGYG000001814_01311;MGYG000000251_01121;MGYG000004517_01292;MGYG000001469_00549;MGYG000003891_01770;MGYG000002113_00203;MGYG000001645_00483;MGYG000002965_01988;MGYG000001186_00373;MGYG000000217_03427;MGYG000002829_03341;MGYG000004719_00253;MGYG000000179_02939;MGYG000001157_00347;MGYG000000185_02697;MGYG000004717_00864;MGYG000004271_02124;MGYG000004526_00583;MGYG000001356_02488;MGYG000002651_00048;MGYG000003858_00045;MGYG000000039_00227;MGYG000000142_01133;MGYG000003355_04406;MGYG000004337_01667;MGYG000004898_00338;MGYG000004833_01801;MGYG000000562_00434;MGYG000004594_00211;MGYG000002563_01003;MGYG000004726_02941;MGYG000004296_02310;MGYG000004158_00495;MGYG000004540_00402;MGYG000000515_00532;MGYG000000312_01585;MGYG000000184_03160;MGYG000001300_00246;MGYG000002223_00595;MGYG000003868_00872;MGYG000004747_01385;MGYG000001553_01735;MGYG000002279_01755;MGYG000002026_00906;MGYG000002545_00160;MGYG000004087_03021;MGYG000000389_00258;MGYG000000258_00990;MGYG000002298_01550;MGYG000000164_02268;MGYG000003921_00807;MGYG000001309_02528;MGYG000001310_00255;MGYG000002393_02328;MGYG000003937_00035;MGYG000002641_00104;MGYG000000365_00889;MGYG000002880_01067;MGYG000000909_00277;MGYG000004667_02980;MGYG000004866_00093;MGYG000002956_00421;MGYG000002528_02846;MGYG000000249_01234;MGYG000000031_01448;MGYG000003494_01022;MGYG000001247_01746;MGYG000000099_00254;MGYG000000146_01613;MGYG000004805_00611;MGYG000000187_01168;MGYG000000262_02774;MGYG000000242_00797;MGYG000002304_00361;MGYG000001786_00366 domain d__Bacteria 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 0.3076923076923077 186801|Clostridia 0.8251748251748252 J 1.0 Belongs to the universal ribosomal protein uS2 family 0.9090909090909091 rpsB 1.0 - 0.9300699300699301 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 0.993006993006993 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1647679 1865683 1806652 1453488 1581215 1981296 1504279 1442839 1374257 1535217 2031250 1902222 1920813 1747033 1693774 1624955 2175126 2047440 1214416 1555962 1709020 2101478 2070713 1503695 1765360 1703131 1654242 2381605 1864277 2112528 1548680 1746002 1495143 1587083 1555678 1605308 1592533 1269088 1897069 1341816 1642257 2192436 2072880 1227139 1653858 1924900 1653335 1257217 2530040 1768005 1573891 1306377 1759316 1404121 1705189 767638 1257709 1390550 1111768 1154569 609464 1676177 1336225 1536499 1616774 878452 1208884 1437473 2520023 1963947 1403385 1611996 1851955 1812358 1051410 2150907 1847638 3412060 2744571 2029745 2185919 2439026 1890566 2301984 1660936 1653085 2407466 2931111 2685459 2103638 2034248 2687630 2582752 1820342 2313332 1978736 2597763 2653443 2347017 2525049 1589927 1947195 2141425 3101617 2242362 3022866 2115707 3019194 3225451 2638789 2535619 2083189 1833277 3095289 947819 382871 489912 493182 405988 374920 550991 708125 544939 443901 354132 650675 436025 525335 592538 105218 350225 123252 450193 550450 734173 192715 437572 0 872766 879604 774213 0 85893 754986 125296 649614 354708 944509 839752 681505 628248 151479 2950668 3221314 0 0 1999569 2169806 0 0 0 0 2277428 0 1712601 3285645 3094610 0 2645425 892632 0 2242683 0 2571073 1203119 2029729 3118471 2394862 2638362 1478951 0 1926611 0 0 5540275 0 2422301 2463531 2800825 0 -(Gln->pyro-Glu)QLLEAGVHFGHQTRR MGYG000000022_01263;MGYG000001300_00246;MGYG000000201_03495;MGYG000002279_01755;MGYG000001675_01243;MGYG000000255_00471;MGYG000000271_00181;MGYG000004271_02124;MGYG000000002_01239;MGYG000000164_02268;MGYG000002517_01401;MGYG000000404_00635;MGYG000001315_00796;MGYG000002274_00630;MGYG000001310_00255;MGYG000003937_00035;MGYG000002042_01031;MGYG000002975_00796;MGYG000004898_00338;MGYG000001814_01311;MGYG000000251_01121;MGYG000002528_02846;MGYG000000562_00434;MGYG000004296_02310;MGYG000004158_00495;MGYG000004540_00402;MGYG000001319_00659;MGYG000004805_00611;MGYG000000187_01168;MGYG000000312_01585;MGYG000001470_02362 domain d__Bacteria 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 0.2903225806451613 186801|Clostridia 0.8709677419354839 J 1.0 Belongs to the universal ribosomal protein uS2 family 0.8064516129032258 rpsB 1.0 - 0.9354838709677419 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLLENLAYVLDGR MGYG000002274_01132;MGYG000000195_01163 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 fprA2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Flavodoxin_1,Flavodoxin_5,Lactamase_B,Lactamase_B_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178778 0 0 0 0 333111 0 0 0 0 273757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 637823 0 0 0 0 1114695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1157025 0 0 0 0 0 0 0 0 0 1759353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 947920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLLGLVC(Carbamidomethyl)AK MGYG000002080_00556;MGYG000003697_01453;MGYG000000272_00830;MGYG000002293_00490;MGYG000002834_00455 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,2FNEG@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center 1.0 rplF 1.0 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02933 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527379 0 0 270181 0 0 0 0 376290 0 401544 0 0 0 0 285023 0 0 0 224461 368512 226253 0 0 0 248900 0 0 0 0 396404 0 146832 0 0 487478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLLGQVC(Carbamidomethyl)SK MGYG000000236_01772;MGYG000001306_02675;MGYG000000196_04004;MGYG000000243_01956;MGYG000003221_02008;MGYG000001346_01504;MGYG000002470_01215;MGYG000000224_00461;MGYG000000054_03873;MGYG000001461_00419;MGYG000003282_01795;MGYG000002478_00784;MGYG000003363_02276;MGYG000000098_01987;MGYG000000043_02831;MGYG000003693_00208;MGYG000000273_00391;MGYG000004479_01417;MGYG000002549_02910;MGYG000000781_00863;MGYG000000042_01076;MGYG000002560_00251;MGYG000001599_01836;MGYG000004185_01148;MGYG000001433_02291;MGYG000002281_02260;MGYG000002291_02240;MGYG000004763_00941 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,2FNEG@200643|Bacteroidia,4AKP6@815|Bacteroidaceae 0.9642857142857143 976|Bacteroidetes 1.0 J 1.0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center 1.0 rplF 1.0 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02933 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 398632 0 0 370719 155906 248642 0 347894 171209 226121 517156 0 0 500584 0 524224 0 0 314811 0 0 245145 0 453531 0 445631 644932 0 0 0 0 0 0 0 400255 0 404903 0 669335 0 0 841824 810562 529295 0 806340 664359 749563 1042247 0 0 1156292 0 825820 0 0 524269 0 0 411482 0 301445 0 759625 878989 0 0 0 0 0 0 0 1485796 0 723567 0 360754 0 0 367840 480541 334499 0 486797 404191 0 482473 0 0 219222 0 374249 0 0 146127 0 0 545712 0 185981 0 378870 332883 0 0 0 0 0 0 0 458590 0 379709 0 766925 0 0 301476 119948 0 0 524468 184577 258262 248126 0 0 273644 0 204044 0 0 147483 0 0 0 0 0 0 266630 422694 0 0 0 0 0 0 0 318115 0 133300 0 171526 0 0 293616 262067 521295 0 607075 622806 341762 696791 0 0 177700 0 704343 0 0 461133 0 0 644957 0 729059 0 443254 402534 0 0 0 0 0 0 0 174158 0 544523 0 -(Gln->pyro-Glu)QLLLAEKAEK MGYG000002298_00901;MGYG000002966_01704;MGYG000000133_01628;MGYG000000301_00396;MGYG000002985_01307;MGYG000000031_02579;MGYG000003012_01436;MGYG000000184_00844;MGYG000000200_00811;MGYG000000806_02010;MGYG000000212_00769;MGYG000003821_00638;MGYG000000142_00939;MGYG000004733_03028;MGYG000000213_01134;MGYG000001338_01638 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3XZ91@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 9.98 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Ribosome;Metabolic pathways;Biosynthesis of secondary metabolites;Terpenoid backbone biosynthesis 1.0 none 1.0 0 466052 400396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332312 0 0 0 0 280284 0 779258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1194069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1567692 1129825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2634398 0 0 0 0 1288943 -(Gln->pyro-Glu)QLLSDEIMGR MGYG000004735_02134 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG2221@1|root,COG2221@2|Bacteria,1UI1A@1239|Firmicutes,25EAA@186801|Clostridia,27UCZ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Nitrite/Sulfite reductase ferredoxin-like half domain 1.0 dsvA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 C_GCAxxG_C_C,Fer4,Fer4_10,NIR_SIR,NIR_SIR_ferr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 462980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLLVAAKK MGYG000002528_00408 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Ribosome;Metabolic pathways;Biosynthesis of secondary metabolites;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 239007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275392 0 293924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 751269 0 217656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLLVAERAEK MGYG000001315_00738;MGYG000002279_00513 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,27V5D@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 S1 RNA binding domain 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Ribosome;Metabolic pathways;Biosynthesis of secondary metabolites;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLLVMTNADNPR MGYG000002545_01217;MGYG000002274_02693;MGYG000000022_02788;MGYG000003899_02226;MGYG000002105_00879;MGYG000003921_00033;MGYG000003166_00833;MGYG000001300_02837;MGYG000001255_00900;MGYG000002040_00906;MGYG000000039_02141 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 524234 611400 1059332 878757 185443 737908 453941 517311 795807 846686 865957 657460 853677 627815 752789 743742 623169 1000549 994416 710775 402620 741846 1016718 519040 692377 683804 767352 1367939 147077 567616 913715 306522 1116946 807334 489113 619533 614456 816920 2128455 1705889 1783819 2571206 1904326 2059502 3068223 1223143 1815428 1045797 2060565 2091513 1367527 2689139 2284191 1181612 2068466 1455414 3095626 2950345 1389205 1088211 1351746 1759184 3386086 2558413 2873636 1584560 688934 1390038 2284206 1755548 1535102 1862337 596905 2234442 1948417 1024832 483388 475924 473109 626522 478836 364175 349566 592080 438956 245710 445213 415008 480942 481763 405235 499768 355349 977802 436982 610917 514322 342169 842569 177888 452163 554748 494180 1352933 235024 525139 543398 352002 304592 725849 525623 211339 361622 252751 626812 871596 1086655 745496 763079 989803 762481 162844 757050 664207 821207 997518 886304 742421 708285 931060 773773 406884 793122 826117 719710 1036846 666363 749075 677582 629598 694351 570750 492274 778038 1094043 902639 831604 555092 145306 660669 710934 765312 473412 0 429081 612724 0 430022 0 498332 514846 392121 190472 235789 441168 482108 395350 432831 515732 0 185154 0 432903 0 0 304841 674790 365827 541035 0 942535 318367 442892 540342 410326 852922 490857 0 484120 396095 -(Gln->pyro-Glu)QLMGPGGGLTIFHGTK MGYG000000196_05082;MGYG000002218_00631;MGYG000000196_01061;MGYG000002549_04148 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,4AP35@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 S 1.0 Tat pathway signal sequence domain protein 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal 1.0 - 1.0 GH109 0.75 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2514907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 993365 0 0 0 0 0 0 0 0 0 1669589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLMQSGGGLTIFHGTK MGYG000003351_05246;MGYG000001346_01665;MGYG000001378_04108;MGYG000001345_03248 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,4AP35@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tat pathway signal sequence domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal 1.0 - 1.0 GH109 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 403113 0 0 0 0 0 0 551782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381515 0 0 0 0 0 0 0 0 558849 0 570217 0 0 0 0 0 0 1883878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690383 320939 0 0 0 0 277785 0 0 0 0 749233 0 0 0 0 0 0 794040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308438 418806 0 0 0 0 326741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 606698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLNLDAIHDTVHEMAKDEAR MGYG000000781_01988;MGYG000001306_02407 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1592@1|root,COG1592@2|Bacteria,4NJ7V@976|Bacteroidetes,2FP1G@200643|Bacteroidia,4AKVP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211614 0 0 0 329906 0 0 0 0 0 533124 0 0 0 0 0 495181 554501 0 0 0 0 935446 0 0 253924 0 0 0 0 0 0 0 0 0 0 245471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64771 0 0 0 98815 0 0 0 0 0 0 0 0 0 0 0 140552 137229 0 0 0 0 369283 0 0 85208 0 187030 0 0 0 0 0 0 0 0 116973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87755 0 0 0 0 204973 0 0 0 0 99760 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLNPMEPIPADKDVR MGYG000000074_01292 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,2FMCE@200643|Bacteroidia,22UZ7@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Belongs to the peptidase M16 family 1.0 - 1.0 - 1.0 - 1.0 ko:K07263 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_M16,Peptidase_M16_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 499030 362929 0 493537 0 461217 330028 0 0 390833 0 0 0 0 364874 0 0 0 300361 0 289849 0 0 391238 416045 338831 0 363499 0 0 358671 359108 0 0 0 279705 0 857652 551547 879706 1238279 827917 711485 801275 1250075 827682 1098911 819341 1030581 496546 1119406 507387 925327 871746 0 1820342 1831333 1183045 826487 0 568395 888218 1081644 964162 0 959889 902568 439956 1059692 963449 0 962282 911328 1130227 639183 371125 469985 0 0 338158 387761 0 0 234917 0 0 510003 0 0 0 0 283417 0 407426 0 330571 448400 0 0 0 0 0 0 0 386749 0 0 352189 0 0 0 0 0 939411 864755 839074 957397 837954 1084765 1228678 1255802 920215 1210723 570266 878756 935900 1013085 1166815 885533 1027148 0 1370378 1039321 1034224 809029 0 749349 1197520 1198339 1210624 0 1079863 608117 724365 841720 777311 0 1043193 978547 1010594 768241 2284435 1567397 2161030 4024401 2479397 2410682 2047335 1879042 2359163 2746314 1705880 1999777 3153465 1511557 2276702 2240182 2809408 0 4208060 3669609 2252746 2194048 0 2645894 2580629 2565944 2347688 0 2655212 3579694 2116830 2053012 1693866 0 2169068 2105747 2991533 2626580 -(Gln->pyro-Glu)QLNTEITR MGYG000000280_01150 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__AM51-8|s__AM51-8 sp003478275|m__MGYG000000280 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,4BWM7@830|Butyrivibrio 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLNVVTTQLGVDAK MGYG000000142_02503;MGYG000004733_01558;MGYG000000171_00589;MGYG000000252_00283;MGYG000000201_00498;MGYG000002298_01761;MGYG000000031_02025;MGYG000000212_01933;MGYG000000002_02254 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase delta subunit 1.0 acsD 1.0 - 1.0 2.1.1.245 1.0 ko:K00194 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLNVVTTQLGVNAQK MGYG000001338_02426;MGYG000000184_00684;MGYG000002312_01596;MGYG000000213_00150 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase delta subunit 1.0 acsD 1.0 - 1.0 2.1.1.245 1.0 ko:K00194 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 914796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150031 594648 0 0 0 0 0 0 0 469479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 847405 518099 0 0 0 0 0 0 0 497037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 583456 898404 907411 0 0 0 0 372508 -(Gln->pyro-Glu)QLPIGKEDDFK MGYG000000077_01356;MGYG000001637_00070;MGYG000000154_02190;MGYG000002528_01099;MGYG000004414_01432;MGYG000000201_03874;MGYG000001338_03374;MGYG000000179_00921;MGYG000000146_01349;MGYG000002492_00343;MGYG000002517_00204;MGYG000001315_01206;MGYG000000262_00029 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia 0.38461538461538464 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 0.9230769230769231 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1145272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLPVYGDGMQIR MGYG000001300_00652;MGYG000001255_00155;MGYG000002040_00632;MGYG000003899_00401;MGYG000003166_01976;MGYG000001627_00377;MGYG000003291_01463 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily 1.0 rfbB 1.0 - 1.0 4.2.1.46 1.0 ko:K01710 1.0 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 1.0 M00793 1.0 R06513 1.0 RC00402 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS02615 1.0 GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 GT2 0.8571428571428571 dTDP-glucose 4,6-dehydratase. - - dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. 1.0 1.0 1.0 1.0 Acarbose and validamycin biosynthesis;Biosynthesis of vancomycin group antibiotics;Polyketide sugar unit biosynthesis;Streptomycin biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 445441 0 0 0 0 0 0 0 421644 0 0 0 0 0 0 249849 0 0 0 0 0 0 254617 0 0 0 0 0 0 0 0 0 0 850295 0 0 0 0 635180 0 0 0 0 0 0 0 794877 0 0 0 0 0 0 747860 0 0 0 0 0 0 458683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 357715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374070 0 0 0 0 429092 0 0 0 0 0 0 0 329700 0 0 0 0 0 0 95551 0 0 0 0 0 0 226555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLQALREELDSK MGYG000002834_00586;MGYG000003697_00203 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,2FNI1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 761618 0 0 0 0 851574 0 0 0 0 894100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLSGKR MGYG000001345_04617;MGYG000003539_00358;MGYG000002534_00332;MGYG000003681_02208;MGYG000002494_02064;MGYG000002506_03025;MGYG000002549_03009;MGYG000000243_01838;MGYG000001489_01493 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,4AMYK@815|Bacteroidaceae 0.5555555555555556 976|Bacteroidetes 0.6666666666666666 H 0.6666666666666666 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 0.6666666666666666 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 0.6666666666666666 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1414582 0 4482393 0 2941063 1727217 2118961 0 2211522 0 2548022 0 3384367 0 1656981 3221659 2040318 0 0 1817519 0 2188387 0 1956515 1769395 2108775 0 0 0 0 3571714 0 7776452 0 1999132 0 2311714 6769279 1409453 0 1593284 0 2191059 1211199 1686372 0 1165818 0 3678816 0 4876998 0 1860263 3344816 1720032 0 0 1481069 0 1295469 0 971557 1528830 2031736 0 0 0 0 1265113 0 963435 0 1885245 0 1480133 1527698 756639 0 1789610 0 1836423 1437009 835983 0 1386397 0 1779117 0 2627478 0 1372786 2150825 908753 0 0 1356619 0 1789555 0 335284 1307828 1398320 0 0 0 0 1057809 0 1527922 0 1626185 0 1273959 1211988 826576 0 427370 0 642165 461284 807517 0 789924 0 915867 0 551401 0 362858 913401 643810 0 0 644122 0 589536 0 321534 758377 810412 0 0 0 0 302896 0 489131 0 965095 0 868954 373935 1022468 0 972739 0 1870360 1174736 1469060 0 1545366 0 2791752 0 2162040 0 742082 971283 972050 0 0 862836 0 1610534 0 2478911 1648373 1643844 0 0 0 0 1901202 0 1399368 0 4066534 0 2998604 1577807 -(Gln->pyro-Glu)QLSLDRDPHGNVQVSLIETEK MGYG000000042_02105;MGYG000001306_00885;MGYG000000138_03763;MGYG000001346_02908;MGYG000000236_04310;MGYG000002033_03229;MGYG000003693_02493;MGYG000003681_01737;MGYG000003701_00980;MGYG000000243_02424;MGYG000003363_03107;MGYG000004479_02550;MGYG000002438_03062;MGYG000000043_01357 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 0.7142857142857143 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 0.9285714285714286 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 932891 0 0 0 0 0 0 0 448900 0 475544 0 0 594107 0 372945 0 0 287957 0 523738 0 0 0 0 558662 0 448551 0 0 1092276 0 0 327063 0 891900 0 0 397349 0 0 0 0 0 0 0 504650 0 269011 0 0 531567 0 0 0 0 0 0 1853720 0 0 0 0 1338500 0 0 0 0 0 0 0 0 0 0 0 0 286930 0 0 0 0 0 0 0 992630 0 591918 0 0 766362 0 721331 0 0 671300 0 598027 0 0 0 0 684864 0 368179 0 0 238740 0 0 388286 0 613198 0 0 0 0 0 0 0 0 0 0 180675 0 295774 0 0 0 0 0 0 0 523782 0 665480 0 0 0 0 0 0 296221 0 0 0 0 0 295135 0 0 0 0 0 0 0 0 0 0 0 0 1011051 0 439167 0 0 383917 0 688029 0 0 1016072 0 614847 0 0 0 0 512117 0 1273559 0 0 0 0 0 147008 0 0 -(Gln->pyro-Glu)QLTADELAAAPAQTK MGYG000002274_02671;MGYG000000022_01634;MGYG000002040_01920;MGYG000002545_01451;MGYG000000573_01090;MGYG000003899_01586;MGYG000003166_00684 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1081285 0 0 0 0 321983 0 0 0 0 314244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228682 0 0 0 0 176862 0 0 0 0 322609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217361 0 0 0 0 266629 0 0 0 0 479803 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 717294 0 0 0 0 644639 0 0 0 0 827046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252582 0 0 0 0 447692 0 0 0 0 540299 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLTAELQR MGYG000000013_00131;MGYG000000029_03029;MGYG000002549_03516;MGYG000003351_03212;MGYG000000054_01820;MGYG000001378_02728 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 161341 0 0 0 0 0 0 563264 361668 0 373970 0 0 200912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286193 0 0 0 0 0 283441 0 0 0 0 0 0 651431 347790 0 333964 0 0 233453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268030 0 0 0 0 0 113766 0 0 0 0 0 0 137451 305877 0 236108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261667 0 0 0 0 0 437541 0 0 0 0 0 0 1183211 419714 0 329576 0 0 394177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454750 0 0 0 0 0 381862 0 0 0 0 0 0 243821 117930 0 216607 0 0 294525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128414 0 0 -(Gln->pyro-Glu)QLTEAIKR MGYG000002926_01578;MGYG000004831_00136;MGYG000001500_00622;MGYG000003819_01324;MGYG000004482_00128;MGYG000002156_01981;MGYG000001616_02088;MGYG000002116_01091;MGYG000002103_00765;MGYG000003589_00969;MGYG000004784_01496;MGYG000004475_00688;MGYG000004276_01515;MGYG000001576_00629;MGYG000002720_00236;MGYG000002794_00964;MGYG000000099_01480;MGYG000004628_02333 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,2N7K8@216572|Oscillospiraceae 0.5555555555555556 186801|Clostridia 1.0 J 0.7777777777777778 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit 0.7777777777777778 rpsR 0.7777777777777778 - 1.0 - 1.0 ko:K02963 0.7777777777777778 ko03010,map03010 0.7777777777777778 M00178 0.7777777777777778 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.7777777777777778 - 1.0 - 1.0 - 1.0 Ribosomal_S18 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.7777777777777778 none 1.0 650847 0 0 0 0 0 0 462134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640779 0 0 0 0 0 0 0 574408 0 0 551925 0 1007719 0 0 0 0 0 0 814810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 665874 0 0 0 0 0 0 0 900224 0 0 710693 0 1063989 0 0 0 0 0 0 1131267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 950329 0 0 0 0 0 0 0 1260173 0 0 1294289 0 663453 0 0 0 0 0 0 726341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632959 0 0 0 0 0 0 0 999140 0 0 583315 0 676928 0 0 0 0 0 0 788448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460876 0 0 0 0 0 0 0 613479 0 0 601243 0 -(Gln->pyro-Glu)QLTFEQSLR MGYG000002298_01714;MGYG000000312_01698;MGYG000000142_02312;MGYG000000212_00041;MGYG000000200_01186;MGYG000004839_01157;MGYG000000242_00809;MGYG000000140_00016;MGYG000002286_02635;MGYG000000031_02755;MGYG000002312_00716;MGYG000003702_01337;MGYG000001338_00212;MGYG000000201_03106;MGYG000004735_01618 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3XZ1G@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 8.87 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP_cyclohyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLTGKEPFK MGYG000000077_00522;MGYG000002528_00169;MGYG000000262_01374;MGYG000000080_02990 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,25VH9@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225162 0 0 0 0 0 0 0 0 0 0 0 1005910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438273 0 0 0 0 0 0 0 0 0 0 0 628920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 952513 0 0 0 0 0 0 0 0 0 0 0 271510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1144508 0 0 0 0 0 0 0 0 0 0 0 1529680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1050038 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLTGKEPSK MGYG000003012_00270;MGYG000002278_00654;MGYG000000123_02326;MGYG000002528_00994;MGYG000000489_01891;MGYG000000200_01023;MGYG000000255_01223;MGYG000000002_00433;MGYG000000181_00382;MGYG000004869_03374;MGYG000000171_01795;MGYG000000152_05170;MGYG000000281_00071;MGYG000000179_03775;MGYG000001689_04245;MGYG000000245_00866;MGYG000001531_01900;MGYG000000271_02474;MGYG000000142_01918;MGYG000004733_01142;MGYG000004087_01928;MGYG000000202_02200;MGYG000002256_00937;MGYG000001065_01063;MGYG000000233_02915;MGYG000000153_02121;MGYG000002974_00091;MGYG000002517_00989;MGYG000003821_01669;MGYG000000133_02344;MGYG000004762_01166;MGYG000004271_00836;MGYG000000198_01270;MGYG000003422_00551;MGYG000000028_00147 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.37142857142857144 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 1651361 1180920 810144 1272828 1759518 1766360 855370 1295382 953014 1374967 1332823 1423513 1523804 1732482 1637958 1509387 1285450 1599526 1360655 1938929 1947052 1886107 1119127 1019832 1193077 1307809 1444089 1236042 1292289 1670634 730277 1228835 832044 2086707 1376731 1258732 1128627 786261 816577 2160283 809932 138087 768018 827537 906512 860465 0 809111 520793 0 0 845515 896303 467223 0 656190 782414 854035 977900 391237 664605 963482 943040 655756 851179 823464 1347290 1245819 1910045 1061698 1134809 1561060 1244059 597732 811295 724922 1440898 2037068 929283 1555471 450792 590151 1090767 1363559 1124517 1384935 584639 1034294 601751 1384863 1853368 1023693 1659228 0 1166949 1408524 1390827 1255184 479714 658336 1233151 1537205 1625777 363321 1204765 1936658 801449 1380546 933485 1857293 1269553 1299650 1544152 758925 4662310 2775671 1746334 5220853 2769022 1822536 2157423 4187945 3092928 2928705 2634582 1869668 1701022 4701458 3634997 2633160 4184106 576390 3324431 3322715 1611740 1732735 203564 1325240 3427253 2958301 7251730 1190252 3226707 3537350 2676094 2454957 2288507 2795932 4201445 4387596 3605286 2115199 2345830 2153127 2352029 1327479 2308164 2318972 1314308 1982498 3348758 3435780 2859378 2897201 1925748 1401125 2934212 3393950 2599102 596995 3152590 2444121 2221152 2479657 1315141 3267718 2658397 3253349 2430708 863458 1232149 2414742 1976188 1971239 2499342 1355686 1424358 1499938 3465209 2603157 -(Gln->pyro-Glu)QLTKEDGTTPK MGYG000000074_00712 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,22U9R@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal protein S1 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 282684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450405 0 0 0 0 145611 0 427841 421792 606463 0 117255 306924 0 370556 199398 0 0 0 237547 0 177336 0 0 227957 389406 328714 0 0 0 112073 0 0 0 543905 333431 405234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322172 0 406752 0 0 0 0 436255 225562 0 0 0 374634 0 0 0 0 287797 295502 335414 0 0 0 0 0 0 0 322710 171322 0 0 1523765 0 0 0 0 1676224 1725663 1352743 1763817 1807847 0 1442906 2324052 0 1674309 1615464 1570862 0 0 2165856 0 1252032 0 1408459 1646968 2459898 1297726 0 0 0 1365612 0 0 0 1891304 2276558 2650588 0 -(Gln->pyro-Glu)QLTLDRDPHGNVQVSLIETEK MGYG000004876_02004;MGYG000002281_01665;MGYG000004797_01062;MGYG000002181_00899;MGYG000001780_01920;MGYG000001313_01096;MGYG000002455_02781;MGYG000002549_01269;MGYG000000054_01445;MGYG000000196_00779;MGYG000004464_00923 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 0.8181818181818182 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 542322 0 0 0 602283 479016 0 440318 618520 0 582209 380418 924316 747990 515420 969835 0 581744 358483 459664 0 499951 580809 527753 0 703556 859154 755117 0 499205 0 348949 0 0 0 773916 643872 0 659442 0 0 0 1059897 839157 0 1099047 832343 0 1504958 1040197 1744459 979849 1052121 1898955 0 639920 816117 925335 0 904016 647077 606963 0 1102873 989967 774633 0 1209714 0 1392983 0 0 0 784701 745606 0 335261 0 0 0 721845 506040 0 375731 252114 0 609072 616634 218266 517871 478328 664355 0 982328 306498 424199 0 238663 738166 623590 0 205921 416907 935994 0 672349 0 0 0 0 0 468572 487012 0 345615 0 0 0 434221 325212 0 116708 253718 0 331347 388302 444288 486007 329460 436674 0 0 390404 357362 0 353117 0 0 0 344899 0 0 0 364605 0 441070 0 0 0 460494 260083 0 733543 0 0 0 1007201 682089 0 825694 766378 0 382462 0 1523359 423616 526077 1368052 0 1334658 775486 1173533 0 562356 1066795 607012 0 713419 420843 1121934 0 1268710 0 529930 0 0 0 659713 606341 0 -(Gln->pyro-Glu)QLTPHPWDALDANLQVGDKVK MGYG000000243_01228;MGYG000002478_02960 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1606649 1603416 3035558 0 3044648 1668474 0 1764825 1601633 1615564 1312304 1552570 3872269 1329350 1390329 2647921 0 1078655 1571258 1253337 1724836 1327614 1383607 1395757 1400749 1636978 2035544 1831361 1504937 2226963 2133298 1861366 3738843 1477349 1876886 0 1520306 2756778 757382 828766 1159903 0 2864053 1217512 0 1504679 1113430 1482456 1654976 1594514 4689154 1372873 1629099 3561099 0 674720 1476600 173101 1144989 1303527 1301378 853897 1517263 1555017 1467740 925355 1056157 1910137 717781 1486557 985190 857411 1428698 0 984997 1008982 520977 388434 442209 0 1235028 788578 0 377416 598321 377683 678232 737996 2274622 616646 575250 1301972 0 1242698 532038 462515 533690 550928 1098539 757974 517995 696961 348748 1193379 801475 512118 781035 335128 405527 335273 758666 0 482965 574179 0 0 0 0 0 0 0 0 0 0 0 0 199006 0 0 152377 0 0 73195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231259 0 0 82331 577401 0 335801 0 2023078 502042 0 443496 265422 250162 0 390830 7909802 1025514 392961 1760175 0 1015553 604196 984785 361536 0 1552627 2526529 870476 1448220 1818861 4229418 0 720012 177616 0 839534 94874 0 0 0 0 -(Gln->pyro-Glu)QLTPHPWDALDENLK MGYG000001630_00344;MGYG000000707_00011;MGYG000002293_00147 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608867 0 0 0 0 0 0 477816 0 0 0 0 588360 0 0 0 0 449852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLTPHPWDALDPNLK MGYG000002218_00698;MGYG000003681_00897;MGYG000003697_01824;MGYG000002080_02027;MGYG000004456_02407;MGYG000004495_00381;MGYG000001783_01031;MGYG000000044_01026;MGYG000001313_02488;MGYG000003693_01627;MGYG000003460_01250 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 0.36363636363636365 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363959 0 0 0 0 168776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724553 0 0 0 0 0 0 2833835 0 0 0 0 3080841 0 0 0 0 2474604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4245208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3236144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLTPHPWDALDSEIK MGYG000001806_00025 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900553965|m__MGYG000001806 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1715599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLTPHPWDALDSELK MGYG000003493_01806;MGYG000003470_00203 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1448027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLTPHPWDALDTDLK MGYG000003312_01455;MGYG000000196_00547;MGYG000001378_02385;MGYG000002281_02540 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 680509 1493602 0 0 868046 0 0 0 0 0 0 0 0 0 0 0 407926 0 691447 0 0 0 0 0 0 0 920219 0 0 0 0 0 0 0 0 0 0 0 1055410 607696 0 0 928209 0 0 0 0 0 0 0 0 0 0 0 704279 0 456529 0 0 0 0 0 0 0 741310 0 0 0 0 0 0 0 0 0 0 0 296415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257077 0 144301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLTPHPWDALDTNLK MGYG000002438_01919 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,22WN9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310536 0 0 0 0 0 0 0 0 0 0 0 0 292364 0 0 0 0 0 0 556700 0 0 0 0 0 0 0 0 528121 0 0 0 0 0 0 0 0 521860 0 0 0 0 0 0 0 0 0 0 0 0 543783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317489 0 0 0 0 0 0 0 0 827388 0 0 0 0 0 0 0 0 328345 0 0 0 0 0 0 0 0 0 0 0 0 749695 0 0 0 0 0 0 817145 0 0 0 0 0 0 0 0 1220894 0 0 0 0 0 0 0 0 1244260 0 705884 0 0 0 0 0 0 -(Gln->pyro-Glu)QLTPHPWDSLDPNLK MGYG000000696_00589;MGYG000001750_01904;MGYG000000355_01785;MGYG000001306_01408;MGYG000001789_00306;MGYG000004622_00252 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 921565 0 0 0 0 1390939 0 0 0 0 1493955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 606890 0 0 0 0 354937 0 0 0 0 446592 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLTPHPWEALDQNLK MGYG000000074_00712 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,22U9R@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal protein S1 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180246 0 0 0 302891 244417 0 0 298976 0 0 0 0 0 0 334389 242484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361057 0 0 0 0 0 0 0 219391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104707 717481 0 617396 881402 1137250 1035775 0 824028 851719 868442 0 650596 0 0 612193 815288 659729 0 1476814 1196130 0 722906 0 571178 1017535 1107361 0 0 0 1233180 0 0 439904 0 968304 0 1180486 704194 -(Gln->pyro-Glu)QLVAEETTK MGYG000000484_00676;MGYG000001496_00483;MGYG000004039_02305;MGYG000001710_01296;MGYG000000217_01905;MGYG000001319_00742;MGYG000001602_01548;MGYG000001311_02470;MGYG000000198_00463;MGYG000000205_01169;MGYG000001531_01705;MGYG000004891_01762;MGYG000000255_00822;MGYG000000233_00090;MGYG000001065_00813;MGYG000000179_05120;MGYG000001622_02526;MGYG000004296_00910;MGYG000001315_00697 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,220V7@1506553|Lachnoclostridium 0.42105263157894735 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1020661 0 0 207994 0 0 285981 0 415948 0 0 0 0 0 397322 0 230822 0 386723 863205 367036 0 0 0 0 412223 586955 0 0 546199 0 325738 0 566629 469540 0 536026 0 0 0 0 0 0 0 386598 350035 505106 0 0 312673 0 0 576058 0 211828 0 407089 0 536795 0 0 0 0 0 409182 0 0 138747 0 0 0 467411 330075 0 332078 411699 395613 0 410114 337492 0 387797 269477 0 551242 0 0 427740 0 0 431212 0 373946 0 261256 493644 433026 559870 0 369218 0 405089 359615 0 0 597117 144670 0 219231 209560 164377 0 369486 281937 380093 0 537816 632585 0 314839 153442 260350 337000 0 0 384190 0 0 296136 0 0 0 179075 486296 0 338111 0 184026 0 464694 228123 0 0 477316 338484 607989 291333 253473 382254 0 265461 586029 1570735 0 1227106 2366781 0 1232880 1576848 936238 2324681 0 0 1535565 0 0 1905922 0 2225521 0 1835145 2333244 1282479 1409521 0 1060943 0 2085241 1547579 0 0 2109356 1207946 1264373 1082734 1834792 825582 0 2258854 1326086 -(Gln->pyro-Glu)QLVEKEK MGYG000003697_00203 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,2FNI1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2871076 0 0 0 0 1779207 0 0 0 0 2645384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 661127 0 0 0 0 1544407 0 0 0 0 875619 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLVGGAGEDTILAR MGYG000001346_02810;MGYG000000224_00999;MGYG000002717_02505;MGYG000000196_01170;MGYG000001337_01654;MGYG000002561_03042;MGYG000001780_02594;MGYG000003351_01171;MGYG000000144_01411;MGYG000004748_03340;MGYG000003312_00309;MGYG000003681_01088;MGYG000000098_00198;MGYG000000013_00875;MGYG000000117_01899;MGYG000002549_00836;MGYG000001378_02596;MGYG000001345_01669;MGYG000002291_00827;MGYG000000105_02956;MGYG000002455_02988;MGYG000001313_02601;MGYG000000054_03643;MGYG000003252_05864;MGYG000000243_01379;MGYG000002171_02922;MGYG000004899_03911;MGYG000003282_01306;MGYG000000029_01582;MGYG000002275_00273 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,2FPNC@200643|Bacteroidia,4ANG3@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 S 0.9333333333333333 UPF0365 protein 0.9333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 YdfA_immunity 0.9333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232605 0 0 0 0 385039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361087 0 0 0 0 396521 0 0 0 0 370737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490600 0 0 0 0 365694 0 0 0 0 722355 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLVGHK MGYG000004797_01999;MGYG000001306_02686;MGYG000002293_00480;MGYG000003697_01442 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,2FMRC@200643|Bacteroidia,4AMR2@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 259092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209261 0 0 0 0 878098 0 0 0 0 1189762 0 0 0 0 1613646 0 0 0 0 1906803 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1183165 0 0 0 0 2981818 0 0 0 0 3336276 0 0 0 0 994161 0 0 0 0 991196 0 0 1044224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 933677 0 0 0 0 1073292 0 0 0 0 1220294 0 0 0 0 0 0 0 0 0 471022 0 0 4314992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2394638 0 0 0 0 2005355 0 0 0 0 3239881 0 0 0 0 3524695 0 0 0 0 3486376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLVYSALNIK MGYG000000195_01573;MGYG000004866_01550;MGYG000003921_01192;MGYG000002651_00836;MGYG000003937_01091;MGYG000001300_00295;MGYG000003899_01136;MGYG000000022_01324;MGYG000004679_00524;MGYG000003166_01334;MGYG000002274_00044;MGYG000002545_00548;MGYG000000084_00623;MGYG000002059_01523;MGYG000000039_00171;MGYG000002040_01715;MGYG000001255_01114;MGYG000001761_00369 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 968040 1532506 2076875 1150772 361832 1012777 903493 814241 957172 1118764 1093197 982415 1934012 1102438 0 1503449 1320049 572646 1381740 1176915 361768 1215353 735119 936652 935823 930412 1194888 894572 0 854951 1127616 903039 1957344 1551150 752283 385103 956639 1337177 1745152 3907247 3584256 2618710 2716273 4182895 3718442 1527595 2591036 911968 2215997 3416928 2667075 2742339 2664717 2016884 3612195 1380891 3480444 3081140 1476238 2949915 1872287 3786588 3709326 2986443 2743138 1604670 0 2420823 4560472 3778076 3139933 2238304 837945 2048890 2046759 3003024 114544 493747 216520 72062 386415 146407 251273 248146 208822 203288 330521 416301 319943 323096 98032 390014 277184 1141553 190194 207951 488677 129128 1162917 344818 201341 189884 199824 1452079 0 457245 367993 282971 73261 290182 224425 181051 222835 177339 409586 323808 568109 307946 385629 331955 577920 182615 428222 234353 373029 1032866 418359 388586 386726 270639 310870 0 409960 183730 775098 231621 0 0 543382 490208 399648 0 0 384753 316155 619220 465561 743069 63292 281334 448321 277003 0 0 630953 71610 124529 126157 247084 294377 0 0 0 546466 0 192978 0 248662 0 999590 136472 0 292211 77374 1114319 212619 234421 0 106517 1488330 0 224890 252572 131368 275592 0 0 232335 0 0 -(Gln->pyro-Glu)QLWWGHR MGYG000003546_00525;MGYG000003554_01593;MGYG000002963_04124;MGYG000002552_01119;MGYG000002549_00666;MGYG000002212_01054;MGYG000001599_01345;MGYG000002485_01178;MGYG000000028_00919;MGYG000000140_01107;MGYG000001770_02254;MGYG000000142_02094;MGYG000003469_00855;MGYG000000249_01473;MGYG000000245_01734;MGYG000000301_00138;MGYG000000138_02053;MGYG000004727_01310;MGYG000002517_00674;MGYG000000184_01152;MGYG000004762_01478;MGYG000000233_00075;MGYG000000271_01901;MGYG000004797_03994;MGYG000001164_02046;MGYG000003922_02194;MGYG000004642_00522;MGYG000000355_00463;MGYG000002050_00390;MGYG000002281_02548;MGYG000000031_03328;MGYG000001447_00042;MGYG000002312_02297;MGYG000002506_03988;MGYG000003363_00444;MGYG000002293_01163;MGYG000000201_00944;MGYG000001688_02000;MGYG000004317_00021;MGYG000002478_02951;MGYG000000222_00614;MGYG000000187_00532;MGYG000004763_01971;MGYG000002234_00068;MGYG000000212_03026;MGYG000002492_02349;MGYG000000213_00326;MGYG000000127_03267;MGYG000002756_00331;MGYG000001337_01539;MGYG000000002_00399;MGYG000002494_02798;MGYG000002985_00329;MGYG000001496_02122;MGYG000002033_00874;MGYG000001306_02859;MGYG000000258_00349;MGYG000002445_00464;MGYG000003697_02045;MGYG000002969_00818;MGYG000002535_03704;MGYG000002247_00836;MGYG000004893_01367;MGYG000002534_04274;MGYG000000262_01172;MGYG000003266_01529;MGYG000001543_01603;MGYG000002218_01736;MGYG000000909_02211;MGYG000003351_04957;MGYG000002528_02643;MGYG000002025_02287;MGYG000004828_00571;MGYG000000562_01100;MGYG000001714_01373;MGYG000002286_01614;MGYG000002737_01862;MGYG000002603_00589;MGYG000001789_02031;MGYG000001698_02715;MGYG000003372_04217;MGYG000002515_04203;MGYG000000076_01416;MGYG000000243_00147;MGYG000002717_01948;MGYG000000133_00022;MGYG000001338_02829;MGYG000001781_02124;MGYG000000038_00666;MGYG000004823_02266;MGYG000001661_01338;MGYG000001707_01441;MGYG000002298_00234;MGYG000004876_03015;MGYG000000312_01562 domain d__Bacteria 1.0 COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,2FPJG@200643|Bacteroidia,4AKPX@815|Bacteroidaceae 0.22105263157894736 186801|Clostridia 0.5368421052631579 J 1.0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner 1.0 valS 1.0 - 0.5684210526315789 6.1.1.9 1.0 ko:K01873 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03665 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 0.9368421052631579 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 0.6631578947368421 - 1.0 - 1.0 - 1.0 GH5_11 1.0 valine--tRNA ligase. valyl-tRNA synthetase. - ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 364034 514581 392219 403351 0 443716 0 0 0 485708 0 369641 542461 0 97119 0 0 0 0 0 0 334470 0 330020 0 330778 0 0 409204 455834 0 374503 472046 0 431742 0 297384 411939 480025 655727 561955 538340 0 833483 0 0 0 792057 0 643660 685102 0 484709 0 0 0 0 0 0 697005 0 738416 0 630590 0 0 528924 632285 0 617695 541153 0 508136 0 459565 569761 468888 370960 578114 538341 0 533340 0 0 0 384563 0 626878 583475 0 516687 0 0 0 0 0 0 728362 0 420806 0 442122 0 0 589222 499433 0 667190 699592 0 613267 0 541059 483563 374531 522051 488357 411579 0 561003 0 0 0 492510 0 421631 645583 0 475788 0 0 0 0 0 0 114916 0 62572 0 472076 0 0 188210 565507 0 686795 69973 0 599711 0 418824 547068 640829 596650 537326 710731 0 645007 0 0 0 667831 0 698912 555632 0 762560 0 0 0 0 0 0 679877 0 538115 0 608279 0 0 987948 716164 0 653484 593873 0 677114 0 718161 746035 -(Gln->pyro-Glu)QLYGESEGKDGK MGYG000000138_02259;MGYG000001489_02765;MGYG000000080_01997;MGYG000002218_01253;MGYG000003425_01378;MGYG000002478_04548;MGYG000002438_00429;MGYG000004797_02953;MGYG000004885_00824 domain d__Bacteria 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,22VVH@171551|Porphyromonadaceae 0.4444444444444444 976|Bacteroidetes 0.7777777777777778 G 1.0 Belongs to the GPI family 0.8888888888888888 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 391912 588946 516668 0 694242 875689 473778 0 418410 479821 0 631111 941314 0 0 917641 643203 758303 313193 0 660617 614692 585504 617899 0 423089 0 744343 461610 605064 557616 916085 445977 327729 641080 446371 625995 382046 497008 731645 575765 0 621330 262581 524655 0 517076 489344 0 382233 689950 0 0 552478 390811 328078 1162705 0 587829 233872 546674 504586 0 491650 0 475473 439138 466701 552519 546905 418320 530209 623141 583393 517495 443651 467302 311791 280065 0 414754 295452 387946 0 375949 723428 0 309266 416807 0 0 580790 588343 643257 2147959 0 635129 0 510693 592079 0 503249 0 512008 296846 277034 567459 876751 308072 169603 767175 331085 601410 298827 317740 284600 325715 0 503773 1016584 0 0 358557 393364 0 264595 565547 0 0 305896 297828 0 293304 0 581532 706004 0 237715 0 424712 0 0 437236 431542 239781 316321 429145 0 481939 261133 169476 315003 426492 411804 503286 0 769190 836994 546325 0 691752 397358 0 889007 662571 0 0 569049 720689 1009393 673221 0 961451 582075 1011660 482228 0 783779 0 957824 1232241 940418 667148 911915 389494 556332 872545 902704 632284 679305 -(Gln->pyro-Glu)QLYGESEGKDQK MGYG000002603_00166;MGYG000003697_00356;MGYG000001770_01372;MGYG000004735_01120;MGYG000003012_00855;MGYG000002445_02761;MGYG000002966_02852;MGYG000001056_00808;MGYG000004689_01366;MGYG000002293_00785;MGYG000000287_02964;MGYG000000806_00684;MGYG000002025_01407;MGYG000002960_01371;MGYG000000133_02455 domain d__Bacteria 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia 0.4 186801|Clostridia 0.6 G 1.0 Belongs to the GPI family 0.6666666666666666 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230059 0 0 0 0 0 0 0 0 0 189452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271412 599116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1159044 0 861798 0 0 0 0 0 963567 0 0 0 0 958424 0 1877942 0 0 0 1098852 2161223 0 805766 0 0 0 0 0 0 0 1015300 0 0 0 0 0 0 0 812594 1324576 350225 0 908197 0 0 0 0 0 0 0 0 588611 577035 0 0 0 922156 0 0 0 728351 1135529 620872 0 791590 0 0 951112 0 947686 0 1173325 0 687412 -(Gln->pyro-Glu)QLYGESEGKENK MGYG000002455_01614;MGYG000001780_00268;MGYG000004876_01420;MGYG000001346_00849;MGYG000003681_00158;MGYG000002171_00278;MGYG000004899_01388;MGYG000000243_00070;MGYG000001313_03153 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,4AKGG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 588769 611692 1392794 511252 1122223 748012 473243 608340 503193 609048 649089 543100 992516 733874 853483 876389 0 951044 585511 594177 0 493933 551872 501982 548133 619158 473705 644500 500935 551978 657385 0 1444738 659088 550022 436041 687116 1424438 494661 367474 460020 356215 468995 424149 347616 430883 496434 524599 424876 624438 401687 411293 377424 334759 0 289498 433396 293031 0 374273 291953 295406 204880 476799 410437 372378 347547 552053 238330 0 359664 458522 621795 472499 446516 505329 749576 760743 905990 589414 1011896 893709 888630 907236 1005660 772079 977392 627602 832142 922663 789343 799087 0 1229633 839233 597682 0 725514 1064661 800981 767488 588384 792825 1105805 832860 681162 813327 0 605797 732321 912857 900443 688965 804973 556682 726183 0 624984 0 1196962 755019 723843 742562 736118 0 966028 935359 694583 717470 0 0 0 601278 562959 0 529783 0 991169 0 0 701777 2343724 675463 674775 815753 0 0 799591 821680 801947 677625 1199680 555189 281434 0 298988 443575 580733 0 183120 678182 991734 1490517 1049481 453569 1046271 630354 0 0 699728 847583 421545 0 581049 565862 503673 0 0 0 664424 0 373752 743293 0 1417589 0 643409 581470 534540 0 -(Gln->pyro-Glu)QLYIHR MGYG000002202_02071;MGYG000000177_01062;MGYG000000146_02457;MGYG000000262_00216 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,27VFV@189330|Dorea 0.5 186801|Clostridia 1.0 QT 1.0 PucR C-terminal helix-turn-helix domain 0.75 cdaR_3 1.0 - 1.0 - 1.0 ko:K02647 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 HTH_30 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1166877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 970883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1761648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1290853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1006408 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLYQHMAK MGYG000002534_00492;MGYG000002494_01841;MGYG000002515_03110 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3105@1|root,COG3105@2|Bacteria,1RE90@1224|Proteobacteria,1S3S2@1236|Gammaproteobacteria,3XPIB@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 oxidoreductase activity 1.0 yhcB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 1.0 - 1.0 ko:K09908 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF1043 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 223306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 863410 0 0 1092276 0 0 0 968131 0 0 0 878445 0 0 0 0 1156784 0 0 1087320 0 971742 0 0 0 0 0 0 0 0 785778 0 0 713482 0 568940 0 0 281834 0 0 484548 0 0 0 264580 0 0 0 227861 0 0 0 0 365681 0 0 412452 0 331305 0 0 0 0 0 0 0 0 174417 0 0 289796 0 203305 0 0 485940 0 0 0 0 0 0 698392 0 0 0 510190 0 0 0 0 367641 0 0 886409 0 404284 0 0 0 0 0 0 0 0 634711 0 0 943298 0 875068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLYSAGIPK MGYG000004732_00520 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__|m__MGYG000004732 1.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 1.0 rpsC 1.0 - 1.0 - 1.0 ko:K02982 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 366984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1289141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QLYVDHTK MGYG000000133_00237;MGYG000000216_00421 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 0.5 186801|Clostridia 1.0 M 0.5 Cobalt chelatase (CbiK) 0.5 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 0.5 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 0 0 0 121846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 108810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15777839 0 16434509 23014774 0 9326026 0 9077627 11188413 20433567 18897209 14765260 9356411 23031789 16538493 11899858 14932748 0 15123664 6325371 18341275 0 0 6848585 11286371 21930313 17145636 0 23327450 5096063 12529497 19739976 20330797 19376373 6572063 14375461 12286927 10869373 -(Gln->pyro-Glu)QM(Oxidation)EVLEAIK MGYG000004785_01065;MGYG000000142_02501;MGYG000000200_00066;MGYG000002312_01594;MGYG000000002_02252;MGYG000003409_00273;MGYG000000216_02769;MGYG000003821_01555;MGYG000001338_02424;MGYG000002966_01692;MGYG000000184_00686;MGYG000000201_00500;MGYG000000263_02678;MGYG000001602_02146;MGYG000000806_02369;MGYG000000050_00432;MGYG000000743_01335;MGYG000000213_00152 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3XZQ5@572511|Blautia 0.7777777777777778 186801|Clostridia 1.0 E 0.8888888888888888 Psort location Cytoplasmic, score 8.87 0.7777777777777778 acsE 0.8888888888888888 - 1.0 2.1.1.258 0.8888888888888888 ko:K15023 0.8888888888888888 ko00720,ko01120,ko01200,map00720,map01120,map01200 0.8888888888888888 M00377 0.8888888888888888 R02289,R10243 0.8888888888888888 RC00004,RC00113,RC01144,RC02871,RC02977 0.8888888888888888 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pterin_bind 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the N(5) group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein.-!-Involved, together with EC 1.2.7.4 and EC 2.3.1.169, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea. (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein] = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+). 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 0.8888888888888888 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QM(Oxidation)FDAEGYEVVAINDLTSPK MGYG000002126_00535;MGYG000000022_00437;MGYG000001255_00370;MGYG000000371_00136;MGYG000002619_02023;MGYG000002641_00563;MGYG000000217_00275;MGYG000001300_02008 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.875 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.875 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13949069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QM(Oxidation)FDAEGYQVVAINDLTSPK MGYG000002098_00013 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01|s__|m__MGYG000002098 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20429713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QM(Oxidation)FGAEGYEVVAINDLTSPK MGYG000000280_02459;MGYG000000038_02185;MGYG000003582_01256;MGYG000001607_01815;MGYG000000204_00778;MGYG000001310_02090;MGYG000004740_01468;MGYG000001319_00348;MGYG000000187_02264;MGYG000000262_01195;MGYG000002517_01026;MGYG000001299_00204;MGYG000000251_00555;MGYG000002528_00367;MGYG000003450_00202;MGYG000002279_00557;MGYG000000398_00286;MGYG000002025_02240;MGYG000000164_00800;MGYG000000271_03250;MGYG000004271_00554;MGYG000000562_01218;MGYG000001421_02311;MGYG000004317_00142;MGYG000000404_00344;MGYG000004735_01946;MGYG000000153_00303;MGYG000002492_01379;MGYG000001652_01009;MGYG000000489_00503;MGYG000004593_01977 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.41935483870967744 186801|Clostridia 0.9354838709677419 G 0.6129032258064516 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5161290322580645 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 267837 0 0 0 0 0 0 0 0 253954 0 0 0 0 0 0 0 0 298831 0 0 0 0 0 0 294766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177581 0 246217 0 0 0 0 0 0 0 0 217215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234934 0 0 0 0 0 0 0 0 0 0 283613 0 0 0 0 0 0 0 0 0 0 90262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34635317 0 0 0 0 0 0 0 0 25129960 0 0 0 0 0 0 0 0 25803920 0 0 0 0 0 0 26115611 0 0 0 0 0 0 0 0 0 0 40385228 0 -(Gln->pyro-Glu)QM(Oxidation)LDDFSRR MGYG000000200_02976;MGYG000001338_00486;MGYG000000212_03361;MGYG000000171_01373 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3XYJC@572511|Blautia 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 943223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMDEC(Carbamidomethyl)EAGDNTGLLLR MGYG000003683_00887;MGYG000002397_00495;MGYG000003452_00658;MGYG000002395_00576;MGYG000000756_01285 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 431682 0 0 280726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 713862 507046 481683 1153516 450371 0 0 0 472226 0 1881129 0 0 632458 0 1795324 0 0 0 550147 344835 1806115 0 0 0 1333977 0 0 966512 0 572301 0 0 0 0 756332 0 0 288914 0 0 0 0 0 0 0 0 0 0 0 0 329194 0 0 0 0 0 393486 0 0 0 0 0 0 0 0 0 0 535778 0 0 0 0 0 0 0 0 0 0 384848 0 0 0 0 284455 0 0 0 0 359492 0 0 0 0 0 641871 0 783018 0 0 0 0 0 0 187302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMDKLDEK MGYG000002834_01606;MGYG000003697_01975;MGYG000001770_00647 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,2FNG9@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 1.0 P 0.6666666666666666 COG0226 ABC-type phosphate transport system, periplasmic component 0.6666666666666666 - 1.0 - 1.0 - 1.0 ko:K02040 0.6666666666666666 ko02010,ko02020,ko05152,map02010,map02020,map05152 0.6666666666666666 M00222 0.6666666666666666 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 0.6666666666666666 3.A.1.7 0.6666666666666666 - 1.0 - 1.0 PBP_like_2 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Tuberculosis;ABC transporters;Two-component system 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1663509 0 0 0 0 2641734 0 0 0 0 2508706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMEENKAQIAK MGYG000001345_03160;MGYG000001337_01162;MGYG000000013_02001;MGYG000002549_04073;MGYG000001378_04005;MGYG000000236_03679;MGYG000000196_04881;MGYG000000029_03397;MGYG000002281_03183 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4372@1|root,COG4372@2|Bacteria,4NJGZ@976|Bacteroidetes,2G2H0@200643|Bacteroidia,4AKNU@815|Bacteroidaceae 0.7777777777777778 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 588112 0 682367 0 734715 0 0 0 0 933078 0 0 0 0 0 0 0 0 0 0 545449 0 675335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448605 0 853256 0 231985 0 0 0 0 1430397 0 0 0 0 0 0 0 0 0 0 611367 0 597766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 412943 0 370424 0 0 0 0 596512 0 0 0 0 0 0 0 0 0 0 304740 0 468385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 558106 0 470522 0 479062 0 0 0 0 943514 0 0 0 0 0 0 0 0 0 0 0 0 222751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 129259 0 485619 0 813267 0 0 0 0 764979 0 0 0 0 0 0 0 0 0 0 780147 0 537919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMEENKEQIAK MGYG000001313_01931;MGYG000004185_01081;MGYG000001346_03599;MGYG000003681_00353 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4372@1|root,COG4372@2|Bacteria,4NJGZ@976|Bacteroidetes,2G2H0@200643|Bacteroidia,4AKNU@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 265566 0 0 0 0 0 0 0 150367 0 453080 448629 0 293846 0 0 0 0 0 0 182155 174111 0 330013 0 228315 0 0 0 322684 134054 0 0 0 0 0 0 0 864663 0 1061772 0 820271 781917 0 0 679999 756722 812642 1629164 0 801696 0 0 0 209073 0 0 673250 757325 386483 483749 0 749406 0 502272 802428 830911 523937 0 778048 0 0 545302 794464 771812 803936 0 1158309 0 1162755 1061535 0 0 1191896 895429 1215967 1081100 0 924448 0 0 0 1243702 0 0 971217 771759 1037843 842701 0 1025435 0 1279423 832557 1075672 1088085 0 782396 0 0 1086398 1141252 850076 628742 0 1030085 0 1061778 721764 0 0 622400 842214 1090040 1192094 0 763496 0 0 0 517402 0 0 636461 880696 0 505489 0 1131341 0 634647 916457 997851 727286 0 1119558 0 0 954203 681883 1010281 0 0 0 0 245919 0 0 0 0 0 785711 0 0 0 0 0 0 422835 0 0 0 207013 0 0 0 0 0 419851 0 461540 0 0 290969 0 0 0 0 0 -(Gln->pyro-Glu)QMEVLEAIK MGYG000004785_01065;MGYG000000142_02501;MGYG000000200_00066;MGYG000002312_01594;MGYG000000002_02252;MGYG000003409_00273;MGYG000000216_02769;MGYG000003821_01555;MGYG000001338_02424;MGYG000002966_01692;MGYG000000184_00686;MGYG000000201_00500;MGYG000000263_02678;MGYG000001602_02146;MGYG000000806_02369;MGYG000000050_00432;MGYG000000743_01335;MGYG000000213_00152 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3XZQ5@572511|Blautia 0.7777777777777778 186801|Clostridia 1.0 E 0.8888888888888888 Psort location Cytoplasmic, score 8.87 0.7777777777777778 acsE 0.8888888888888888 - 1.0 2.1.1.258 0.8888888888888888 ko:K15023 0.8888888888888888 ko00720,ko01120,ko01200,map00720,map01120,map01200 0.8888888888888888 M00377 0.8888888888888888 R02289,R10243 0.8888888888888888 RC00004,RC00113,RC01144,RC02871,RC02977 0.8888888888888888 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pterin_bind 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the N(5) group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein.-!-Involved, together with EC 1.2.7.4 and EC 2.3.1.169, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea. (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein] = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+). 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 0.8888888888888888 none 1.0 0 0 0 0 0 0 0 0 0 0 670597 0 0 0 0 0 0 0 264205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 118129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMFDAVC(Carbamidomethyl)AAC(Carbamidomethyl)GK MGYG000000039_01677;MGYG000002223_00262;MGYG000003291_01619;MGYG000000589_01601;MGYG000002272_00439;MGYG000002545_01146;MGYG000003899_00602;MGYG000003166_00747;MGYG000002641_01194;MGYG000002274_00854;MGYG000001255_02057;MGYG000001300_02903;MGYG000002651_01055;MGYG000002224_01668 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Probable zinc-ribbon domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-trcl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 417731 465406 975284 878158 0 499905 533123 239782 601147 528999 385711 0 348482 844089 425862 435709 466813 584002 1122322 562645 0 555180 607450 738345 631147 785189 550669 1308948 0 160776 573103 234393 742754 835080 235094 442355 430037 698540 1332016 1127261 1436418 1948999 881892 1420987 2329737 854554 1561156 438743 870540 1169843 1016515 2292253 1957971 1255393 2227090 829208 2880371 2016773 883697 957066 1035878 867524 2114531 1825981 1934363 921801 0 973311 1155961 934383 1551642 1487218 502720 1202322 1453878 1059230 0 0 0 0 0 0 0 0 271508 0 0 0 331517 402897 0 0 0 1123308 0 0 148583 0 1045460 0 0 324141 0 1209209 0 0 0 0 0 177072 0 0 0 165730 505486 249778 385196 633479 489916 861288 1054287 341484 682802 539008 0 663560 601335 726624 714675 310052 290448 400846 860412 149648 633395 0 306376 0 599664 743122 636787 0 0 1049282 302206 286894 435974 1542313 0 778407 759493 437267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721643 0 0 0 0 821551 0 0 0 0 640401 0 0 0 0 0 0 0 133897 0 0 -(Gln->pyro-Glu)QMFDAVC(Carbamidomethyl)ASC(Carbamidomethyl)GK MGYG000003937_01603;MGYG000004732_00815 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Probable zinc-ribbon domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-trcl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 205547 0 0 0 0 0 264446 0 0 0 0 494472 0 0 0 0 404066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746220 0 0 0 0 0 693589 0 0 0 0 631978 0 0 0 0 617928 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMFEAEGYEVVAINDLTSPK MGYG000004732_01055;MGYG000000215_01375;MGYG000003937_01177 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 0.6666666666666666 C 0.6666666666666666 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28333051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMFGAEGFEIVAINDLTSPK MGYG000000301_01012;MGYG000000212_01474;MGYG000000171_00850;MGYG000000002_02120;MGYG000002212_00259;MGYG000002966_00075;MGYG000001338_02547;MGYG000000133_02283;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000001315_01699;MGYG000003702_00925;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 981187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2870960 369720 0 0 0 0 0 0 1546145 0 0 0 215011 0 0 5012945 0 0 0 0 0 0 0 0 0 777936 0 0 0 0 0 0 0 0 0 0 0 0 0 2462223 0 0 0 0 5541808 0 0 0 0 1887770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5409323 848241 0 0 0 2435335 0 440610 4276303 975509 0 0 0 0 0 0 0 0 0 0 208187 0 0 0 0 0 0 0 0 0 0 369423 402129 0 0 0 0 3947230 3812625 3448907 0 0 213575 0 3142294 7600482 8673774 6602692 0 0 0 0 0 0 0 0 3615840 0 13897593 0 0 0 0 0 0 0 0 0 0 7006703 3946444 0 0 0 0 7585240 10464993 16064280 0 0 9285366 0 5722737 -(Gln->pyro-Glu)QMFGAEGYEVVAINDLTSPK MGYG000000280_02459;MGYG000000038_02185;MGYG000003582_01256;MGYG000001607_01815;MGYG000000204_00778;MGYG000001310_02090;MGYG000004740_01468;MGYG000001319_00348;MGYG000000187_02264;MGYG000000262_01195;MGYG000002517_01026;MGYG000001299_00204;MGYG000000251_00555;MGYG000002528_00367;MGYG000003450_00202;MGYG000002279_00557;MGYG000000398_00286;MGYG000002025_02240;MGYG000000164_00800;MGYG000000271_03250;MGYG000004271_00554;MGYG000000562_01218;MGYG000001421_02311;MGYG000004317_00142;MGYG000000404_00344;MGYG000004735_01946;MGYG000000153_00303;MGYG000002492_01379;MGYG000001652_01009;MGYG000000489_00503;MGYG000004593_01977 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.41935483870967744 186801|Clostridia 0.9354838709677419 G 0.6129032258064516 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5161290322580645 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 480344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450303 0 0 0 0 0 0 0 0 0 0 0 0 330860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 589897 0 0 0 0 0 0 0 0 0 0 315521 0 4144471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5728994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15241371 0 -(Gln->pyro-Glu)QMHDLKPAPGAK MGYG000001292_02343;MGYG000002469_01750;MGYG000003683_01119 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4D0R9@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 binds to the 23S rRNA 1.0 rplO 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1420415 0 0 0 0 542349 0 0 0 0 1179874 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 145331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMKDAIIK MGYG000000243_02364;MGYG000000042_02977;MGYG000001787_00060 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,4AKHK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMMNDFASR MGYG000000133_00637 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3XYJC@572511|Blautia 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468208 0 0 0 0 0 0 0 0 0 0 739950 0 0 0 0 0 0 498427 0 0 0 0 0 0 0 0 0 0 0 834202 0 0 0 0 389290 -(Gln->pyro-Glu)QMNVQFISHDKINQLR MGYG000000255_01546 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,21Z64@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 EK 1.0 COG COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Aminotran_MocR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 514132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMNYSEYESDQFKK MGYG000002438_03723 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1155@1|root,COG1155@2|Bacteria,4NIB6@976|Bacteroidetes,2FMQ6@200643|Bacteroidia,22WQG@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit 1.0 atpA 1.0 - 1.0 3.6.3.14,3.6.3.15 1.0 ko:K02117 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn 1.0 - 1.0 - 1.0 - 1.0 - 1.0 H(+)-transporting two-sector ATPase. | Na(+)-transporting two-sector ATPase. mitochondrial ATPase. | sodium-transporting two-sector ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. | A multisubunit ATPase transporter found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis.-!-The enzyme is similar to EC 7.1.2.2 but pumps Na(+) rather than H(+). cf. EC 7.2.2.3 and EC 7.2.2.4.-!-Formerly EC 3.6.3.15. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. | ATP + H2O + 4 Na(+)(in) = ADP + H(+) + 4 Na(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 529676 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMQFFAAR MGYG000003683_00301;MGYG000000756_01431;MGYG000002469_00869;MGYG000001292_01825 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 Pyruvate formate lyase-like 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bac_luciferase,Fer4_12,Gly_radical,PFL-like,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146125 0 0 0 0 0 0 0 0 0 0 0 436592 0 0 0 64725 98292 306273 0 0 0 356916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMQFFGAR MGYG000003872_00149;MGYG000002534_00608;MGYG000002534_01733;MGYG000000235_02550;MGYG000002354_02556;MGYG000002507_03821;MGYG000002506_00229;MGYG000001712_00487;MGYG000002438_01173;MGYG000002057_00708;MGYG000003420_01555;MGYG000000421_00811;MGYG000001913_00352;MGYG000002415_02033;MGYG000000323_00781;MGYG000000093_01913;MGYG000001464_02452;MGYG000002159_01115;MGYG000002963_00984;MGYG000004453_00589;MGYG000004632_01941;MGYG000002504_03659;MGYG000000215_01434;MGYG000002494_01739;MGYG000002515_00999;MGYG000000034_01553;MGYG000001326_00363;MGYG000002477_04855;MGYG000000919_01916;MGYG000004743_00132;MGYG000002654_00807;MGYG000001395_02012;MGYG000001325_00972;MGYG000003301_00377;MGYG000002727_01362;MGYG000002494_01412;MGYG000001763_01402;MGYG000003410_00860;MGYG000003470_01473;MGYG000002965_00898;MGYG000001749_02186;MGYG000002535_00167;MGYG000002912_00356;MGYG000001692_01065;MGYG000002535_02788;MGYG000003549_00903;MGYG000002506_02759;MGYG000001405_03199;MGYG000000989_01728 domain d__Bacteria 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36F8M@31979|Clostridiaceae 0.14285714285714285 186801|Clostridia 0.3673469387755102 C 0.9591836734693877 formate acetyltransferase 0.32653061224489793 pflB 0.8367346938775511 - 0.5918367346938775 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 0.673469387755102 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 209988 221552 259144 44470 240014 233849 224918 387213 256771 88550 0 0 63418 102852 286439 0 161241 0 153803 185147 0 404657 0 336368 371771 234449 202297 0 80297 276273 63477 0 216171 74443 451188 207286 75838 165393 561193 1200005 900566 636728 1558285 2585259 922821 575541 564302 1195774 0 0 780373 919539 753184 1324377 1536068 0 1014770 655651 0 3280931 0 2173035 1248518 671999 531414 0 1560801 1144521 474361 0 986016 486589 599956 512277 580486 1015382 331341 323186 367921 152766 86131 652048 433101 501407 97439 664588 0 0 345618 371360 390739 361355 406271 0 328384 333177 0 488840 0 581121 423985 442190 427076 0 407470 347493 392278 0 388330 449984 340109 85814 356261 128730 83972 84220 61653 167254 60926 155007 0 122559 62533 172208 0 0 93533 0 69352 70714 74750 0 76183 101911 0 105201 0 0 0 83077 101790 0 0 142005 65211 0 77286 79089 153230 107278 57607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMQVGGKDPLVPEENDKTTVIALR MGYG000002504_04484;MGYG000002477_00514;MGYG000002534_00089;MGYG000002323_04146;MGYG000002494_02311;MGYG000003372_02790;MGYG000002506_03300;MGYG000000235_03676;MGYG000002515_03814 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 K 1.0 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits 1.0 rpoZ 1.0 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03060 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1109683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268297 0 806019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMSLTLHRPPGR MGYG000002961_00589;MGYG000003266_01369;MGYG000002947_00479;MGYG000004681_01011;MGYG000002775_01356 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CU9G@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 - 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMTEVTDIDGHK MGYG000002293_02198;MGYG000002834_01646;MGYG000003697_02473 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FM0N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 8-amino-7-oxononanoate synthase 1.0 bioF 1.0 - 1.0 2.3.1.29,2.3.1.47 1.0 ko:K00639,ko:K00652 1.0 ko00260,ko00780,ko01100,map00260,map00780,map01100 1.0 M00123,M00573,M00577 1.0 R00371,R03210,R10124 1.0 RC00004,RC00039,RC00394,RC02725 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine C-acetyltransferase. | 8-amino-7-oxononanoate synthase. 2-amino-3-ketobutyrate coenzyme A ligase. | AONS. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. | The enzyme catalyzes the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis.-!-Pimeloyl-CoA can be used with lower efficiency. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. | 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism;Metabolic pathways;Biotin metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 748134 0 966047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMTFEQSLR MGYG000000133_00307;MGYG000000301_00956 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3XZ1G@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP_cyclohyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 849131 0 0 0 0 0 -(Gln->pyro-Glu)QMTGKEPSK MGYG000004740_00081;MGYG000002492_01740;MGYG000003694_01621 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 512934 0 0 959314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 800827 0 0 0 0 532123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMTGSDFSEITK MGYG000003215_00872;MGYG000000164_02761;MGYG000000249_01548;MGYG000000146_01048;MGYG000002279_01069;MGYG000000038_01579 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3XZ12@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2351558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QMVAHALTK MGYG000002528_00945;MGYG000000233_00055 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,26AUV@186813|unclassified Clostridiales 0.5 186801|Clostridia 1.0 I 0.5 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF 0.5 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 698262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1751736 0 0 0 0 1065265 0 0 0 0 1699482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466468 0 0 0 0 1040674 0 0 0 0 1617139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QN(Deamidated)ASVFSTQR MGYG000002517_00608 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 163296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1307629 0 0 0 0 0 0 1936425 1843475 805186 0 0 0 1510804 1973199 0 0 0 0 0 0 0 0 0 0 1777842 1993978 0 0 1371255 0 0 0 0 0 0 1765578 0 0 0 0 0 0 0 0 0 0 274493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246247 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QN(Deamidated)GEHGVWQYK MGYG000000489_02253;MGYG000000076_02271;MGYG000000187_02311;MGYG000002492_02848;MGYG000000271_00907;MGYG000002517_02750;MGYG000001637_01313 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 L 1.0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site 1.0 mfd 1.0 - 1.0 - 1.0 ko:K03723 1.0 ko03420,map03420 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03400 1.0 - 1.0 - 1.0 - 1.0 CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF,UB2H 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Nucleotide excision repair 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789274 0 0 0 0 489909 0 0 0 0 725267 0 0 0 0 0 0 0 269484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 765795 0 0 0 0 794560 0 0 0 0 939012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243452 0 0 0 0 0 0 0 0 0 0 485210 0 0 0 0 0 0 0 515609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297087 461925 0 0 0 0 0 0 0 0 0 523284 0 0 0 0 0 0 0 544808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8282668 249684 0 0 0 0 493353 0 0 0 0 552800 0 0 0 0 0 0 0 8004985 0 0 -(Gln->pyro-Glu)QN(Deamidated)PSFGHPEK MGYG000000213_01298 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp003477525|m__MGYG000000213 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia,3WGYT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 MCRA family 1.0 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 462515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNAHNMVVQTNK MGYG000002478_01460 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG3534@1|root,COG3534@2|Bacteria,4NGKW@976|Bacteroidetes,2FM0F@200643|Bacteroidia,4AMJ6@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Carbohydrate binding domain protein 1.0 - 1.0 - 1.0 3.2.1.55 1.0 ko:K01209 1.0 ko00520,map00520 1.0 - 1.0 R01762 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH51 1.0 - 1.0 Alpha-L-AF_C,CBM_4_9 1.0 3.2.1.55 1.0 GH51 1.0 GH51 1.0 GH51 1.0 non-reducing end alpha-L-arabinofuranosidase. arabinosidase. Acts on alpha-L-arabinofuranosides, alpha-L-arabinans containing (1,3)- and/or (1,5)-linkages, arabinoxylans and arabinogalactans.-!-Some EC 3.2.1.23 and EC 3.2.1.38 enzymes also hydrolyze alpha-L- arabinosides. cf. EC 3.2.1.185.-!-Formerly EC 3.2.1.79. Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604539 0 0 0 0 763945 0 0 0 0 414467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258065 0 0 0 0 387325 0 0 0 0 453454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1499895 0 0 0 0 967216 0 0 0 0 956623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3618718 0 0 0 0 3253417 0 0 0 0 2612501 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNAIIFSTER MGYG000004276_00442;MGYG000002926_01410 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 121304 0 0 0 0 0 225089 202001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270018 268451 0 0 0 0 0 0 0 168936 0 0 0 0 587751 969725 0 919918 0 0 0 827621 0 0 0 0 519600 757487 701517 502627 584961 0 0 0 0 0 0 0 825471 1195697 0 0 0 0 0 0 0 701394 0 0 630808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334035 0 370273 0 0 0 522515 0 0 0 0 0 762511 0 0 0 0 0 0 0 0 0 0 0 138716 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNC(Carbamidomethyl)IILSSQR MGYG000004475_00656 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900556015|m__MGYG000004475 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 836642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNDIIYVTPNK MGYG000002478_00603;MGYG000002478_02532 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1596@1|root,COG1596@2|Bacteria,4NNJT@976|Bacteroidetes,2FNYD@200643|Bacteroidia,4AKVB@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 COG1596 Periplasmic protein involved in polysaccharide export 1.0 - 1.0 - 1.0 - 1.0 ko:K01991 1.0 ko02026,map02026 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02000 1.0 1.B.18 1.0 - 1.0 - 1.0 Poly_export,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Biofilm formation - Escherichia coli 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 839616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564542 0 0 0 0 267145 0 0 0 0 456219 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNDILAIVK MGYG000000200_01193;MGYG000000184_01884;MGYG000002312_00710;MGYG000004785_01922;MGYG000001338_00217 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3Y05R@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 344375 103319 0 167612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99110 574786 0 0 0 0 0 0 0 693935 0 0 160907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596071 336705 57765 0 0 0 0 0 0 355202 0 0 74836 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230975 427954 74038 0 0 0 0 0 0 351119 109077 0 153534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530534 220926 157612 0 0 0 0 164314 0 534047 330280 0 100907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456460 695112 435705 0 0 0 0 231297 -(Gln->pyro-Glu)QNDVLAIVK MGYG000000164_00893 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3Y05R@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 429245 0 0 0 0 0 763429 0 469628 0 0 0 307128 396333 301986 0 0 0 0 0 730844 0 0 0 454876 450740 416299 0 388953 0 0 0 0 0 0 590290 441422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78988 0 0 0 0 0 0 0 0 0 0 0 97246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1390382 0 0 0 0 0 0 208135 0 0 0 0 151078 0 0 121786 0 0 0 0 0 0 424732 0 0 0 0 0 0 0 0 122116 0 109280 0 0 0 0 136140 0 0 0 0 0 0 0 0 0 0 98971 0 117758 0 170734 0 0 0 0 0 0 129987 198369 0 -(Gln->pyro-Glu)QNGDWEYANFADDNENGYTVK MGYG000002492_00221 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,25VT8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1522467 0 0 0 0 1048899 0 0 0 0 1561828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNGEHGVWQYK MGYG000000489_02253;MGYG000000076_02271;MGYG000000187_02311;MGYG000002492_02848;MGYG000000271_00907;MGYG000002517_02750;MGYG000001637_01313 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 L 1.0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site 1.0 mfd 1.0 - 1.0 - 1.0 ko:K03723 1.0 ko03420,map03420 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03400 1.0 - 1.0 - 1.0 - 1.0 CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF,UB2H 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Nucleotide excision repair 1.0 none 1.0 708598 463909 0 712609 0 430523 221376 252790 550088 732668 795802 520449 0 596886 370829 801906 682827 1051510 585290 752261 607100 462983 1306917 363890 620339 625786 418308 1298617 0 398431 0 0 0 600837 0 683541 645713 0 0 141364 467536 243141 0 0 0 0 218375 0 205882 0 0 0 0 448526 0 1729127 0 0 0 0 1716777 0 0 0 0 4009863 0 0 0 0 578924 0 0 187623 0 715043 839108 1181902 1327108 696253 0 457501 495505 871657 859193 818683 472685 461060 0 865083 1119408 1050931 717218 611536 559600 712501 505250 564769 867378 465384 1120602 546833 1076228 1535669 0 749371 0 0 1403570 777575 0 691012 1069721 1168199 1543172 159623 437503 1633164 0 610428 1265244 1888230 2045268 988293 1062115 904643 0 1734793 1924508 941830 1892038 874784 1323676 1668980 1919337 0 0 647643 2189814 1587577 1541140 399134 0 1414388 0 0 531639 860051 0 1400230 1569924 619617 1834494 1593897 1894131 0 0 1488338 1515054 1474879 1452101 2331564 1381206 1530530 0 1871205 2519680 1643992 1849728 955377 1833461 1319920 552963 1610150 1721409 2122309 2160018 1566261 2003872 1409864 0 1030610 0 0 2010935 1922729 0 1825548 1945778 1825449 -(Gln->pyro-Glu)QNHEPYSMDAAMAK MGYG000001500_03163;MGYG000004196_00482;MGYG000004475_01030;MGYG000004487_00391;MGYG000002794_01608;MGYG000002720_01506;MGYG000002926_00639;MGYG000002143_01787 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2N683@216572|Oscillospiraceae 0.875 186801|Clostridia 0.875 I 1.0 Psort location Cytoplasmic, score 9.97 0.875 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 0.875 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 783194 686116 441282 0 665976 864963 993312 1282772 1035770 0 0 0 0 877441 1182114 0 0 0 691429 0 0 531562 0 962243 783106 1035024 957522 0 869071 0 0 676194 463752 978560 0 1241831 906970 604214 0 0 0 0 0 0 0 125723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 137748 0 0 0 0 0 0 0 0 0 239441 0 314899 0 297585 0 0 0 376706 386865 364042 0 0 0 0 411806 455326 0 0 0 689042 0 0 382240 0 0 473956 360082 334415 0 333332 0 0 0 343584 295415 0 282363 290590 342685 0 466690 353590 0 0 190907 304688 0 0 0 0 0 0 403986 398937 0 0 0 220791 0 0 0 0 0 359956 439277 503255 0 522351 0 0 358684 377558 0 0 0 0 305133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNIEAVTNDAFMR MGYG000001300_00301;MGYG000002223_00312 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Radical SAM domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,Radical_SAM,SPASM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203927 0 581659 0 0 0 0 0 1068131 0 0 0 0 0 0 755294 0 0 817183 0 1246723 0 0 0 0 0 1025098 880640 882822 0 0 0 0 0 0 0 0 537490 516913 0 0 0 0 0 0 0 190546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 186644 0 0 0 0 0 290882 0 0 0 0 0 0 243500 0 0 232242 0 150599 0 0 0 0 0 291496 189969 0 0 0 0 0 0 0 0 0 234136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNLAQQER MGYG000000107_04662;MGYG000000107_02891;MGYG000002494_04260;MGYG000002506_02537;MGYG000002323_03405 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,3XMMK@561|Escherichia 0.8 1236|Gammaproteobacteria 1.0 G 0.8 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate 1.0 tktA 1.0 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,ic_1306.c2990 0.8 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNLATFC(Carbamidomethyl)QTWDDENVHK MGYG000002515_02735;MGYG000002506_00791;MGYG000002323_02099;MGYG000002506_03156;MGYG000002515_01515;MGYG000002323_00193 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,1RNSQ@1236|Gammaproteobacteria,3XMMA@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria 1.0 gadB 0.6666666666666666 GO:0003674,GO:0003824,GO:0004351,GO:0006873,GO:0006885,GO:0008150,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019725,GO:0030003,GO:0030004,GO:0030641,GO:0042592,GO:0045852,GO:0048878,GO:0050801,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 1.0 4.1.1.15 1.0 ko:K01580 1.0 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 1.0 M00027 1.0 R00261,R00489,R01682,R02466 1.0 RC00299 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECUMN_1333.ECUMN_1747,iUTI89_1310.UTI89_C1707,ic_1306.c1922 0.6666666666666666 Pyridoxal_deC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate decarboxylase. L-glutamate 1-carboxy-lyase. The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate. H(+) + L-glutamate = 4-aminobutanoate + CO2. 1.0 1.0 1.0 1.0 GABAergic synapse;Type I diabetes mellitus;Taurine and hypotaurine metabolism;Butanoate metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Quorum sensing;beta-Alanine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 576599 765679 0 667959 1782871 715771 1359484 587465 984220 0 0 596950 737744 0 546125 0 0 773311 526990 0 1314212 0 1267770 498141 0 773463 0 0 811133 0 0 628378 680481 820740 0 0 866198 0 0 0 0 0 799593 0 0 0 0 0 0 260011 0 0 0 0 0 0 0 0 665647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 626361 0 465710 0 507577 0 0 851261 0 0 693703 0 0 0 0 0 434259 0 486677 0 0 0 0 0 0 0 0 376382 0 580066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187039 0 0 0 0 0 0 0 0 0 0 193553 349529 0 0 0 0 0 0 0 0 0 193157 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNLTSPDGNLK MGYG000001306_00997 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,2FKZT@200643|Bacteroidia,4AMS4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG NOG06228 non supervised orthologous group 1.0 susB 1.0 GO:0000272,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0004558,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:0090599,GO:1901575 1.0 3.2.1.20,3.2.1.3 1.0 ko:K01187,ko:K21574 1.0 ko00052,ko00500,ko01100,map00052,map00500,map01100 1.0 - 1.0 R00028,R00801,R00802,R01790,R01791,R06087,R06088 1.0 RC00028,RC00049,RC00077 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH31,GH97 1.0 - 1.0 GH97_C,GH97_N,Glyco_hydro_97 1.0 3.2.1.3|3.2.1.20 1.0 GH97 1.0 GH97 1.0 GH97 1.0 alpha-glucosidase. | glucan 1,4-alpha-glucosidase. maltase-glucoamylase. | lysosomal alpha-glucosidase. Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.-!-The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links. | Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides.-!-This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides.-!-EC 3.2.1.20 from mammalian intestine can catalyze similar reactions. Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. | Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1542124 0 0 0 0 2223545 0 0 0 0 2879238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1551826 0 0 0 0 2607433 0 0 0 0 2857958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559552 0 0 0 0 0 0 0 0 0 414657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1987332 0 0 0 0 4416195 0 0 0 0 8766094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1286722 0 0 0 0 983283 0 0 0 0 957516 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNNDFTVELEENHR MGYG000000074_00310 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 2FK1S@1|root,34BPZ@2|Bacteria,4P558@976|Bacteroidetes,2FYSJ@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Bacterial protein of unknown function (YtfJ_HI0045) 1.0 - 1.0 - 1.0 - 1.0 ko:K07109 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 YtfJ_HI0045 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736487 710440 0 0 0 0 0 0 0 0 0 990586 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNPADVEALMAC(Carbamidomethyl)K MGYG000001300_00245;MGYG000002272_01434;MGYG000000022_01262;MGYG000003291_01082;MGYG000003166_00302;MGYG000002040_00320 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298141 0 0 470776 0 0 0 0 0 0 0 0 0 540154 0 0 0 0 494315 422814 0 0 0 0 630933 460707 333798 0 0 0 383314 0 0 0 0 0 339545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254006 0 0 0 0 0 0 0 0 0 0 341439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNPEKAAR MGYG000002298_00647;MGYG000000164_01756;MGYG000001338_02036;MGYG000000142_01058;MGYG000000200_00183;MGYG000000002_01844;MGYG000000212_02086;MGYG000000031_03215;MGYG000000171_02087 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3XZ4K@572511|Blautia 0.5555555555555556 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNPEKAER MGYG000000133_02129 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 210520 0 0 0 0 0 0 0 0 0 364551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732156 0 924397 1329999 0 0 1157827 0 633521 1224447 1810675 0 1171747 1894212 0 643827 0 0 628330 0 1037671 0 0 0 1029195 1040770 1364234 0 1471251 0 1206864 0 2092867 0 0 1628658 949262 803974 -(Gln->pyro-Glu)QNPITSIKDQNR MGYG000003697_00848;MGYG000002293_01475;MGYG000002960_00382;MGYG000002834_00840 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase C1-like family 1.0 pepC 1.0 - 1.0 3.4.22.40 1.0 ko:K01372 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_C1,Peptidase_C1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 bleomycin hydrolase. aminopeptidase C (Lactococcus lactis). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain.-!-Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity.-!-Known from bacteria as well as eukaryotic organisms.-!-Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates.-!-Belongs to peptidase family C1. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 484962 606930 0 0 0 0 0 0 644705 0 0 0 0 1075545 0 0 0 596465 420421 0 0 0 0 748246 0 0 0 0 339549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196510 0 0 0 0 0 0 0 0 0 396064 0 0 0 0 1539243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1955160 0 1120796 1266886 0 0 0 0 0 0 985549 0 0 0 0 2005026 0 0 0 1271471 2514971 896540 0 0 0 2014516 0 0 0 0 1399432 0 0 0 0 1378941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNTQQNSNVEKIEK MGYG000003693_02982 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia,4AMCZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682810 0 0 0 0 1496606 0 0 0 0 1006161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 556643 0 0 0 0 632447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNVFTDPQKPMK MGYG000001338_02425;MGYG000000301_00509;MGYG000000142_02502;MGYG000000200_00067;MGYG000000133_01786;MGYG000004735_00332;MGYG000000216_02768 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 0.8571428571428571 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism;Carbon metabolism 1.0 none 1.0 0 423541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 892943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 434635 0 0 0 0 0 0 0 0 0 0 1045897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1030421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1335831 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNVVLATIEALK MGYG000002492_00392 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNVVLATLNALSQLK MGYG000002517_02856 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1106813 0 714529 0 0 0 0 765714 679234 1102585 0 0 0 0 0 745455 0 0 0 0 0 0 0 0 0 1307557 0 0 0 1060440 0 0 0 1312493 0 0 579567 0 -(Gln->pyro-Glu)QNVYTDPQKPMK MGYG000000171_00588;MGYG000000184_00685;MGYG000002298_01760 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism;Carbon metabolism 1.0 none 1.0 0 589423 0 0 0 799787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 584440 0 0 0 0 0 0 0 0 328703 0 0 0 0 0 0 0 0 996266 0 0 0 155230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 668653 0 170142 0 0 0 0 0 0 1147299 0 0 0 0 0 0 0 0 646859 0 0 0 232771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 570058 0 451987 0 0 0 0 0 0 210961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270665 0 0 0 0 0 0 247044 0 0 0 0 0 0 0 0 0 0 0 0 536572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QNYIIVNSEK MGYG000000074_01846 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,2FQDW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1120708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QPDAMTHPDGMQIK MGYG000002476_04117;MGYG000003372_03956;MGYG000002535_04634;MGYG000002515_03227;MGYG000002494_02024;MGYG000002323_00362;MGYG000001692_02603;MGYG000002502_00525;MGYG000002534_00367;MGYG000002500_04458;MGYG000002477_00211;MGYG000002504_03997 order d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales 1.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,3XPHB@561|Escherichia 0.9166666666666666 1236|Gammaproteobacteria 0.9166666666666666 K 1.0 class I promoters have a single CRP-binding site upstream of the RNA polymerase (RNAP)- binding site, whereas in class II promoters the single CRP- and RNAP-binding site overlap, CRP making multiple contacts with RNAP. Class III promoters require multiple activator molecules, including at least one CRP dimer. It can act as an activator, repressor, coactivator or corepressor. Induces a severe bend in DNA (about 87 degrees), bringing upstream promoter elements into contact with RNAP. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP. High levels of active CRP are detrimental to growth. Plays a major role in carbon catabolite repression (CCR). CCR involves cAMP, adenylate cyclase (cyaA), CRP and the EIIA-Glc component of the PTS (crr). In the presence of glucose EIIA-Glc is dephosphorylated, and does not activate adenylate cyclase, leading to reduced cAMP and thus decreased CRP activity. Also plays a role in many other processes (see PubMed 22573269) 0.9166666666666666 crp 1.0 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 0.9166666666666666 - 1.0 ko:K10914 1.0 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03000 1.0 - 1.0 - 1.0 - 1.0 Crp,HTH_Crp_2,cNMP_binding 0.9166666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Biofilm formation - Vibrio cholerae;Biofilm formation - Escherichia coli;Biofilm formation - Pseudomonas aeruginosa;Two-component system;Quorum sensing 1.0 none 1.0 1430939 454747 1611635 0 1989644 436165 1810448 0 0 1315505 0 0 0 0 0 0 2996984 0 2127953 0 0 1331176 0 2688125 2195868 552486 0 0 2235758 0 0 0 2356865 0 0 0 2727227 713418 2159320 490794 779983 0 637814 1071322 664979 0 0 1825598 0 0 0 0 0 0 1611732 0 877976 0 0 1220595 0 2020862 1907178 1506046 0 0 1840162 0 0 0 830109 0 0 0 2112717 2723328 2387865 1796435 2226434 0 2924042 2804645 2794560 0 0 798626 0 0 0 0 0 0 3330896 0 2236914 0 0 2320404 0 650378 2345817 2657863 0 0 2681130 0 0 0 2624365 0 0 0 2419560 2947425 2104624 2423719 2474280 0 1976343 2212499 414145 0 0 976688 0 0 0 0 0 0 2554252 0 1959195 0 0 2582328 0 3346891 2588281 2324186 0 0 333760 0 0 0 546685 0 0 0 158723 2088318 2467313 2304375 2232602 0 2622501 2069622 955581 0 0 2224673 0 0 0 0 0 0 306528 0 2723973 0 0 826262 0 1621109 1089669 1542516 0 0 2854937 0 0 0 629681 0 0 0 1291387 1994027 -(Gln->pyro-Glu)QPDGSLAGDHYK MGYG000000022_00344 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,248C0@186801|Clostridia,3WH1J@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 glucuronate isomerase 1.0 uxaC 1.0 - 1.0 5.3.1.12 1.0 ko:K01812 1.0 ko00040,ko01100,map00040,map01100 1.0 M00061,M00631 1.0 R01482,R01983 1.0 RC00376 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 LacI,UxaC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucuronate isomerase. uronic isomerase. Also converts D-galacturonate to D-tagaturonate. D-glucuronate = D-fructuronate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1609786 0 0 0 0 1617708 0 0 0 0 1370226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564463 0 0 0 0 955172 0 0 0 0 653867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 972025 0 0 0 0 1482796 0 0 0 0 1465522 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QPDGSRHPFDSFIVAK MGYG000002545_01342;MGYG000002040_01325;MGYG000000187_02007 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia,3WHXZ@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 1.0 IQ 1.0 Psort location Cytoplasmic, score 0.6666666666666666 - 1.0 - 1.0 1.1.1.69 0.6666666666666666 ko:K00046 0.6666666666666666 - 0.6666666666666666 - 1.0 - 0.6666666666666666 - 0.6666666666666666 ko00000,ko01000 0.6666666666666666 - 1.0 - 1.0 - 1.0 adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 gluconate 5-dehydrogenase. 5-ketogluconate reductase. - (1) D-gluconate + NADP(+) = 5-dehydro-D-gluconate + H(+) + NADPH. (2) D-gluconate + NAD(+) = 5-dehydro-D-gluconate + H(+) + NADH. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1218940 0 0 0 0 1124589 0 0 0 0 1442368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80876 0 0 0 0 288371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618924 0 0 0 0 600923 0 0 0 0 481647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QPEASGDLR MGYG000003681_00522;MGYG000001306_00929;MGYG000003693_01486;MGYG000000781_01663 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia,4ARQC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 589874 0 0 0 0 0 0 0 0 0 135970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490381 0 0 0 0 839477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371464 0 0 0 0 309726 0 0 0 0 483416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1386125 0 0 0 0 0 0 0 0 0 956545 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QPFPGPGLGIR MGYG000001310_00986;MGYG000004847_02038;MGYG000000142_01325;MGYG000000171_01555;MGYG000002528_01386;MGYG000002610_00542;MGYG000004288_01478;MGYG000004735_01261;MGYG000001423_03192;MGYG000000140_02756;MGYG000002223_00095;MGYG000003482_00900;MGYG000000488_00920;MGYG000001602_01517;MGYG000003899_01640;MGYG000003577_01198;MGYG000003828_00369;MGYG000000184_02045;MGYG000002641_00286;MGYG000000915_01126;MGYG000003683_00702;MGYG000000087_02408;MGYG000002274_01246;MGYG000000271_01306;MGYG000000919_02508;MGYG000002835_00594;MGYG000000022_02285;MGYG000001300_00155;MGYG000002298_01935;MGYG000002619_02218;MGYG000002469_00855;MGYG000000187_01380;MGYG000001637_01668;MGYG000002279_02383;MGYG000003628_01363;MGYG000000028_00428;MGYG000000515_01866;MGYG000000242_02030;MGYG000000489_01853;MGYG000001652_00716;MGYG000004296_00217;MGYG000004548_02048;MGYG000001707_02152;MGYG000003422_00594;MGYG000003166_01352;MGYG000000251_01432;MGYG000000200_03164;MGYG000001255_01096;MGYG000001338_03497;MGYG000000216_01091;MGYG000000269_00045;MGYG000000389_01945;MGYG000001374_02320;MGYG000002492_00550;MGYG000002517_02553;MGYG000004733_00652;MGYG000001711_01546;MGYG000000133_02533;MGYG000000213_01020;MGYG000000387_00949;MGYG000001315_00172;MGYG000000194_00055;MGYG000002670_00532;MGYG000001292_01833;MGYG000000204_01415;MGYG000000398_02147;MGYG000001793_01311;MGYG000003486_00521;MGYG000001490_00760;MGYG000001777_00693;MGYG000004797_02013;MGYG000000212_02358 domain d__Bacteria 1.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3WGXK@541000|Ruminococcaceae 0.2777777777777778 186801|Clostridia 0.8888888888888888 F 1.0 Catalyzes the synthesis of GMP from XMP 0.9861111111111112 guaA 1.0 - 0.9305555555555556 6.3.5.2 0.9861111111111112 ko:K01951 0.9861111111111112 ko00230,ko00983,ko01100,map00230,map00983,map01100 1.0 M00050 1.0 R01230,R01231,R08244 1.0 RC00010,RC00204 1.0 ko00000,ko00001,ko00002,ko01000,ko01002 0.9861111111111112 - 1.0 - 1.0 - 0.9861111111111112 ATP_bind_3,GATase,GMP_synt_C,NAD_synthase,ThiI,tRNA_Me_trans 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 GMP synthase (glutamine-hydrolyzing). GMP synthetase (glutamine-hydrolyzing). Involved in the de novo biosynthesis of guanosine nucleotides.-!-An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain.-!-The enzyme can catalyze the second reaction alone in the presence of ammonia.-!-Formerly EC 6.3.4.1. ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate. 0.9861111111111112 0.9861111111111112 0.9861111111111112 0.9861111111111112 Purine metabolism;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 448522 523317 497817 628570 568490 594140 506007 417516 0 0 0 0 0 392101 510047 0 485684 350097 491087 551666 497337 768849 680344 280408 810312 445218 249513 905071 490607 0 0 458910 267572 438381 0 439509 375551 543354 467270 720132 497253 733069 538800 534973 786621 1333515 0 0 0 0 0 933755 373240 0 637365 1209875 956192 733447 233486 457216 636693 756518 1034229 700352 641056 911448 791637 0 0 538315 430821 803374 267907 621763 592804 257282 557409 680340 436738 396691 241483 380392 304417 494562 0 0 0 0 0 267234 786494 0 422637 316895 533353 428643 547676 536405 400762 283343 769218 285921 565713 506376 273148 0 0 549977 579813 593374 734408 262768 428230 471988 585281 456732 620203 626930 650073 603660 648267 604077 0 0 0 0 0 582497 555166 0 621649 354607 683800 803913 743759 463569 474625 596038 647991 521879 298775 441613 454975 0 0 621000 545801 490783 389266 571566 569577 688284 192600 0 0 0 175279 189116 0 136564 0 0 0 0 0 266673 191761 0 219318 83925 246919 198194 0 298331 263237 0 208059 0 156502 377927 0 0 0 0 401098 227711 321697 273012 194156 190296 -(Gln->pyro-Glu)QPFPGPGLGVR MGYG000000177_00259;MGYG000001622_03026;MGYG000000650_02217;MGYG000001564_01569;MGYG000002478_04002;MGYG000001311_04643;MGYG000001374_02303;MGYG000001346_03291;MGYG000002218_01878;MGYG000002685_01245;MGYG000000383_00024;MGYG000002438_02747;MGYG000003351_04375;MGYG000000198_03851;MGYG000000044_00075;MGYG000001617_00853;MGYG000001617_00899;MGYG000000172_03526;MGYG000001345_00044;MGYG000000222_01345;MGYG000000312_02550;MGYG000000032_05843;MGYG000000150_00351;MGYG000001780_04179;MGYG000001615_05534;MGYG000000029_03508;MGYG000000121_02100;MGYG000004863_00474;MGYG000000622_01763;MGYG000000378_00210;MGYG000000198_00134;MGYG000004735_00074;MGYG000000174_03354;MGYG000000138_02270;MGYG000001651_01803;MGYG000000098_03146;MGYG000000013_02510;MGYG000002727_00995;MGYG000004769_01556;MGYG000001619_01813;MGYG000001356_00700;MGYG000004899_02570;MGYG000003324_00600;MGYG000001493_04160;MGYG000002455_02568;MGYG000002004_00749;MGYG000000133_02443;MGYG000004630_02361;MGYG000000179_04192;MGYG000004762_01920 domain d__Bacteria 1.0 COG0519@1|root,COG0519@2|Bacteria,4NZSX@976|Bacteroidetes,2FNJE@200643|Bacteroidia,4AMZI@815|Bacteroidaceae 0.32 186801|Clostridia 0.64 F 1.0 Catalyzes the synthesis of GMP from XMP 0.32 - 0.8 - 0.68 6.3.5.2 1.0 ko:K01951 1.0 ko00230,ko00983,ko01100,map00230,map00983,map01100 1.0 M00050 1.0 R01230,R01231,R08244 1.0 RC00010,RC00204 1.0 ko00000,ko00001,ko00002,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 GATase,GMP_synt_C,NAD_synthase 0.8 - 1.0 - 1.0 - 1.0 - 1.0 GMP synthase (glutamine-hydrolyzing). GMP synthetase (glutamine-hydrolyzing). Involved in the de novo biosynthesis of guanosine nucleotides.-!-An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain.-!-The enzyme can catalyze the second reaction alone in the presence of ammonia.-!-Formerly EC 6.3.4.1. ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate. 1.0 1.0 1.0 1.0 Purine metabolism;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 208154 0 170296 431935 0 0 203270 0 387012 0 0 0 0 251292 0 347689 0 0 363276 0 0 0 0 0 386576 1008697 0 0 0 0 0 0 200256 274285 0 318037 369036 195714 177121 0 173870 297591 0 0 448598 0 169205 0 0 0 0 338443 0 849568 0 0 280859 0 0 0 0 0 1722362 516773 0 0 0 0 0 0 85456 1003632 0 282376 151273 1081819 192557 0 0 0 0 0 253569 0 0 0 0 0 0 0 0 0 0 0 181988 0 0 0 0 0 102137 0 0 0 0 0 0 0 0 0 0 0 0 0 178982 0 222980 349019 0 0 92963 0 0 0 0 0 0 195815 0 772831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374564 0 0 0 0 0 564542 0 494846 747287 0 0 566394 0 531953 0 0 0 0 734981 0 512931 0 0 670091 0 0 0 0 0 638145 621119 0 0 0 0 0 0 842343 706458 0 557551 649693 572771 -(Gln->pyro-Glu)QPSDEKPTYWEK MGYG000000022_00469 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,3WHNA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 purine-nucleoside phosphorylase 1.0 deoD 1.0 - 1.0 2.4.2.1 1.0 ko:K03784 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Metabolic pathways;Nicotinate and nicotinamide metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 755385 0 0 0 0 215947 0 0 0 0 336532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 906773 0 0 0 0 635194 0 0 0 0 446476 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QPSNSSTGELDTTALNYNK MGYG000002492_00430;MGYG000002670_00445 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,25UXG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1237560 0 0 0 0 499243 0 0 0 0 1071953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QPSQEELSIAR MGYG000002506_00321;MGYG000002494_01268;MGYG000002477_03573;MGYG000003372_00988;MGYG000002534_01961 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria 0.8 1236|Gammaproteobacteria 1.0 S 1.0 Belongs to the WrbA family 0.8 wrbA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016043,GO:0016491,GO:0016651,GO:0016655,GO:0022607,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 1.6.5.2 1.0 ko:K03809 1.0 ko00130,ko01110,map00130,map01110 1.0 - 1.0 R02964,R03643,R03816 1.0 RC00819 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FMN_red 1.0 - 1.0 AA6 1.0 AA6 1.0 - 1.0 NAD(P)H dehydrogenase (quinone). vitamin-K reductase. The enzyme catalyzes a two-electron reduction and has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone.-!-The animal, but not the plant, form of the enzyme is inhibited by dicoumarol.-!-Formerly EC 1.6.99.2. (1) a quinone + H(+) + NADH = a quinol + NAD(+). (2) a quinone + H(+) + NADPH = a quinol + NADP(+). 1.0 1.0 1.0 1.0 Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 346867 0 257420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1580411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1604371 0 1189997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QPSQEEMEK MGYG000000022_02066;MGYG000001255_00882;MGYG000000078_01938;MGYG000002223_01610;MGYG000003656_01457;MGYG000000274_02973;MGYG000000389_02289;MGYG000000195_00502;MGYG000000089_00814;MGYG000002098_00269;MGYG000002552_01350;MGYG000003702_01345;MGYG000002517_00745;MGYG000003921_02148;MGYG000000278_00036;MGYG000000187_00590;MGYG000002492_02033;MGYG000000154_00158;MGYG000000589_00988;MGYG000000271_02213;MGYG000002651_01773;MGYG000001300_01639;MGYG000003694_01134;MGYG000001652_01458 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia 0.375 186801|Clostridia 1.0 C 0.7083333333333334 alcohol dehydrogenase 0.4166666666666667 adh 0.7083333333333334 - 0.7083333333333334 - 0.5833333333333334 - 0.5833333333333334 - 0.5833333333333334 - 0.7083333333333334 - 0.5833333333333334 - 0.5833333333333334 - 0.5833333333333334 - 1.0 - 1.0 - 1.0 Fe-ADH 0.5833333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.5833333333333334 0.5833333333333334 0.5833333333333334 0.5833333333333334 0.5833333333333334 none 1.0 561048 0 361562 716760 0 0 0 589547 637597 672047 0 0 0 692297 801224 0 0 657439 564334 541116 0 0 1280760 0 742496 581652 596255 1478841 0 0 192757 0 364289 0 464399 605002 526924 403300 439982 0 436662 601645 0 0 0 396851 554161 236405 0 0 0 529850 561185 0 0 699245 551511 487826 0 0 758599 0 86525 483542 481881 1083909 0 0 362302 0 574782 0 253853 320761 448399 434586 676862 0 543615 502690 0 0 0 523411 464101 423635 0 0 0 645997 595502 0 0 652537 599103 466177 0 0 693652 0 643096 726505 633138 686285 0 0 521474 0 494850 0 382245 583003 671710 455209 804034 0 432470 785204 0 0 0 886593 966924 540950 0 0 0 1039889 981484 0 0 364979 869471 949669 0 0 526690 0 1352109 1262458 995350 517124 0 0 418769 0 465910 0 1157622 934645 1212108 444791 597195 0 746303 0 0 0 0 523964 601574 856822 0 0 0 797253 818934 0 0 903663 693235 522969 0 0 1002613 0 1132381 946597 987166 1267570 0 0 489917 0 781428 0 700197 1391921 1052318 722927 -(Gln->pyro-Glu)QPSQEEMEKLLK MGYG000002517_00745;MGYG000003921_02148;MGYG000000271_02213;MGYG000001300_01639;MGYG000002098_00269;MGYG000001652_01458 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia 0.5 186801|Clostridia 1.0 C 0.8333333333333334 alcohol dehydrogenase 0.5 adh 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 Fe-ADH 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QPVKEPLQTGIK MGYG000002272_00433;MGYG000004464_00315;MGYG000000195_00672;MGYG000002794_01431;MGYG000000039_00039;MGYG000002040_00951;MGYG000004679_00015;MGYG000001300_02370;MGYG000000022_01422;MGYG000003291_01611;MGYG000001655_01488;MGYG000003899_00594;MGYG000002545_01159;MGYG000002610_02019;MGYG000003697_01834;MGYG000002651_01642 domain d__Bacteria 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae 0.8125 186801|Clostridia 0.8125 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 0.8125 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 0.8125 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 678440 713656 765058 0 0 595472 492454 0 0 0 396691 0 0 861878 0 0 0 0 917585 915609 0 678437 0 627238 627725 716705 696588 0 0 0 580345 0 925228 0 0 0 756058 596938 1320607 1055295 1316096 0 0 1149287 1460947 0 0 0 869072 0 0 1481354 0 0 0 0 1952623 1180752 0 811585 0 919525 1912486 1390866 1310724 0 0 0 1091653 0 1268472 0 0 0 1558062 1312964 0 351627 565694 0 0 0 462414 0 0 0 0 0 0 0 0 0 0 0 485179 372181 0 0 0 0 0 498777 0 0 0 0 501631 0 0 0 0 0 594597 0 830723 192637 1551252 0 0 1280576 1328012 0 0 0 1126050 0 0 1221927 0 0 0 0 1624191 1156216 0 983968 0 1045833 1386663 1247156 916245 0 0 0 1143554 0 1352722 0 0 0 1185315 1362082 0 277695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 329040 0 270396 0 0 0 0 0 -(Gln->pyro-Glu)QPVKEPLQTGLK MGYG000001975_01278;MGYG000004464_00315;MGYG000001056_00148;MGYG000004758_01459;MGYG000002040_00951;MGYG000002224_01680;MGYG000004679_00015;MGYG000004456_02417;MGYG000001300_02370;MGYG000003291_01611;MGYG000000022_01422;MGYG000003812_00624;MGYG000003899_00594;MGYG000002545_01159;MGYG000002960_01412;MGYG000003697_01834;MGYG000002051_00534;MGYG000002651_01642 domain d__Bacteria 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae 0.5 976|Bacteroidetes 0.5 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 - 0.5 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 0.5 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1361697 0 0 0 0 0 0 0 0 0 0 0 0 1663853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QPVNQPLQTGLK MGYG000001661_02014;MGYG000004876_02547;MGYG000002549_01706;MGYG000002281_02651;MGYG000002171_00080;MGYG000000196_02101;MGYG000002478_03339;MGYG000001313_01542;MGYG000001346_00381;MGYG000004797_02195;MGYG000003201_00723;MGYG000000243_00489;MGYG000000013_03749;MGYG000001378_01038 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,2FM4H@200643|Bacteroidia,4AKBP@815|Bacteroidaceae 0.9285714285714286 976|Bacteroidetes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 - 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456909 0 0 0 0 475072 0 0 0 0 482808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375058 0 0 0 0 264796 0 0 0 0 256284 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QPVQVNEAAGFVVNR MGYG000002224_01332;MGYG000001255_01113;MGYG000002272_01496;MGYG000003166_01335 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1793302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1294415 0 0 0 0 0 0 0 0 0 2204077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1165966 0 0 0 0 0 0 0 0 0 1838617 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQAAGTTTLQPK MGYG000002293_00972;MGYG000002080_02252;MGYG000003697_01780;MGYG000002834_01787;MGYG000002960_00648 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,2FU05@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 Outer membrane protein beta-barrel domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OMP_b-brl,OMP_b-brl_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 138631 296850 0 0 0 0 0 0 0 0 366633 0 0 0 0 404166 0 0 0 0 0 0 0 0 0 0 202280 0 0 0 0 0 0 174120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 767127 0 0 0 0 0 210738 0 0 0 0 0 0 1651981 0 0 0 0 0 0 0 0 0 219566 0 0 212739 0 0 0 0 0 0 196707 2341096 2297096 9975608 0 3739901 7427440 0 3243897 2050589 0 4133484 4555000 5090869 0 0 2607543 1768691 12571075 0 0 1469337 8175808 16646143 8906277 2636181 3206136 0 9603660 0 0 4194797 3605970 9651290 4009694 3566198 3233131 2330377 8561908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQDAALAAK MGYG000003693_02255 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1525934 0 0 0 0 2591222 0 0 0 0 1647253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378513 0 0 0 0 331589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQEFDIIHAHDWLTYPAGVHAK MGYG000002560_03190;MGYG000001346_03285;MGYG000001661_02656;MGYG000000243_01312;MGYG000002171_02171;MGYG000001378_02334;MGYG000004797_02601;MGYG000002478_03183 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0438@1|root,COG0438@2|Bacteria,4NEWR@976|Bacteroidetes,2FMW0@200643|Bacteroidia,4AKN5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Glycosyltransferase, group 1 family protein 1.0 gmhA 1.0 - 1.0 2.4.1.346 1.0 ko:K13668 1.0 - 1.0 - 1.0 R11703,R11704 1.0 - 1.0 ko00000,ko01000,ko01003 1.0 - 1.0 GT4 1.0 - 1.0 Glyco_trans_4_4,Glyco_transf_4,Glyco_transf_5,Glycos_transf_1,SIS_2 1.0 - 1.0 GT4 1.0 GT4 1.0 GT4 1.0 phosphatidyl-myo-inositol dimannoside synthase. mannosyltransferase. The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs). (1) a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D- myo-inositol] + GDP-alpha-D-mannose = a 2,6-O-bis(alpha-D- mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+). (2) a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl- (1<->6)-D-myo-inositol] + GDP-alpha-D-mannose = 2-O-(alpha-D-mannosyl)-6- O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 104570 402986 578165 0 0 343053 0 0 0 372487 948370 0 0 0 0 269167 0 0 0 0 429068 0 0 0 0 844497 0 975686 1361036 872668 840838 0 2044045 0 0 683762 0 0 362334 306795 359768 0 0 807268 0 0 0 770934 1316075 0 0 0 0 0 0 0 0 0 330921 0 0 0 0 0 0 2083626 0 932664 1859621 0 0 0 0 0 0 0 0 0 2591025 0 0 0 0 0 0 0 0 0 0 0 0 1608991 0 0 0 0 921116 0 0 0 0 2372641 0 0 0 1398992 0 0 0 0 0 1680125 0 0 0 0 0 0 0 0 0 0 0 0 66207 0 0 0 0 1044837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1466083 0 0 128104 0 0 0 0 0 -(Gln->pyro-Glu)QQEIDYLNEHGFAADFTK MGYG000002171_00958;MGYG000004797_01307;MGYG000002478_00672;MGYG000000243_02714 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,2FMRA@200643|Bacteroidia,4AKJP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 argininosuccinate synthase 1.0 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Fluid shear stress and atherosclerosis;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 634806 0 911379 0 0 0 0 0 0 0 758184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 781354 0 0 0 0 748119 0 0 0 0 0 0 0 0 0 0 0 0 1549896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1249574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9747491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQFDKPSVLNR MGYG000002478_00821;MGYG000000243_01995 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,2FUNX@200643|Bacteroidia,4ARQ8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS21 family 1.0 rpsU 1.0 - 1.0 - 1.0 ko:K02970 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S21 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 728746 0 0 0 0 677082 0 0 0 0 814864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2051992 0 0 0 0 469538 0 0 0 0 2270414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1341333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3894747 0 0 0 0 4258513 0 0 0 0 3691626 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQFDKPSVTK MGYG000000196_03967;MGYG000001337_03914;MGYG000001378_05049;MGYG000002561_02155;MGYG000004748_01295;MGYG000001345_04677;MGYG000000098_02024;MGYG000001346_01539 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,2FUNX@200643|Bacteroidia,4ARQ8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS21 family 1.0 rpsU 1.0 - 1.0 - 1.0 ko:K02970 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S21 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327363 0 0 0 0 523877 0 0 0 0 315337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 671357 0 0 0 0 742320 0 0 0 0 736556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 500728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQGNLDYTDLYDKR MGYG000002549_02817;MGYG000000098_00813;MGYG000000196_04138;MGYG000001433_02399;MGYG000002281_01804;MGYG000001345_00398 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,4AN6T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG2086 Electron transfer flavoprotein beta subunit 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 637410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 503599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQHSDVRPSR MGYG000003372_00912;MGYG000002494_02547;MGYG000002535_03948 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,3XNQ9@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 1.0 S 1.0 Uncharacterised protein family UPF0047 0.6666666666666666 yjbQ 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 UPF0047 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 826875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 968507 0 708212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 821031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQIASDIEFIR MGYG000001313_01931;MGYG000004185_01081;MGYG000000105_02066;MGYG000001346_03599;MGYG000003681_00353 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4372@1|root,COG4372@2|Bacteria,4NJGZ@976|Bacteroidetes,2G2H0@200643|Bacteroidia,4AKNU@815|Bacteroidaceae 0.6 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181693 0 0 0 444169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 145384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQIASDIEFIRK MGYG000001313_01931;MGYG000004185_01081;MGYG000000105_02066;MGYG000001346_03599;MGYG000003681_00353;MGYG000004748_03718 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4372@1|root,COG4372@2|Bacteria,4NJGZ@976|Bacteroidetes,2G2H0@200643|Bacteroidia,4AKNU@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 294907 361196 0 0 0 515063 0 370574 465861 710082 0 688769 309847 427687 540961 556894 398271 709503 0 0 0 398284 460863 823290 0 277072 807179 540097 703809 0 627018 0 488151 683952 410279 292035 306398 0 0 386709 504044 0 0 1550324 0 355819 1439277 0 0 0 699078 0 605717 1386100 0 468993 0 0 673654 0 962828 646375 0 713247 694176 629981 0 0 0 0 0 0 0 0 848109 1211439 772352 712886 808231 930390 0 1032903 858352 920991 675233 991950 0 1141797 698254 820794 757045 712677 897834 1701357 0 0 879360 607616 1212662 1033332 813998 660424 698803 1171597 718468 0 961572 0 643913 822077 935235 880816 857831 761557 568552 256509 504948 614791 0 363943 620467 446871 536600 592580 0 814908 570988 399301 544477 518763 532267 275439 0 0 507754 493344 619422 321003 713927 572615 582364 221102 558628 0 527561 0 532529 1057792 768138 407369 456373 352088 0 382629 251517 525721 0 275663 473634 749806 0 0 0 210065 0 437290 435060 418704 291442 504192 0 0 486446 0 530643 0 332961 188653 278239 657659 0 0 467676 0 0 620877 611621 0 0 414731 -(Gln->pyro-Glu)QQIEEATSDYDREK MGYG000002515_04060;MGYG000002507_03180;MGYG000002494_02676;MGYG000002385_03148;MGYG000002323_03824;MGYG000002506_03866 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,3XN1I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 567959 1170694 507501 991133 603201 1430509 1262869 1628085 679573 1302080 0 492260 633769 1165950 962762 513129 637975 0 930737 731400 1116066 1910919 0 1949913 1374218 650697 1105317 0 620888 1359771 582046 752895 741773 1265877 1471793 1097151 819693 795082 3087142 4538722 4434915 2827784 3720221 9629651 2872657 2694430 3088819 5397005 1487956 2257412 2490321 3182195 3054862 3209007 6000048 0 3885750 2644950 3382781 8139174 0 7144749 4340526 2912440 2329860 0 5477547 3836772 1743821 3160315 4463314 3082513 2530257 3036077 2365964 4689168 1071747 924797 995492 540834 837166 2070172 1167725 1336457 876164 1157174 989555 566379 726309 980917 1052159 881530 757337 0 986147 618214 976189 1136407 0 1577066 1370444 574149 1119415 0 854442 1050834 873016 679222 1010086 1298037 1043328 1129024 694112 880481 994398 995953 1195656 1060179 960070 1469916 1279519 1376707 1096182 1506771 889845 1035120 1098540 1076406 175240 852433 1046320 0 615544 954660 996214 1801860 0 1168405 1245676 1119127 991750 0 1206028 1060709 617750 1086915 1171810 1616400 1550796 1285185 882336 933776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQIEEATSDYDREKLQER MGYG000002515_04060;MGYG000002494_02676;MGYG000002506_03866 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,3XN1I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 865630 0 0 0 893329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 787374 0 944139 0 0 0 0 0 0 0 0 0 889697 1123055 0 0 0 0 505530 0 0 0 860705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040508 0 486149 0 0 0 0 0 0 0 0 0 363316 0 0 0 0 0 813845 0 0 0 808001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363631 0 655708 0 0 0 0 0 0 0 0 0 454834 722717 0 0 0 0 340920 0 0 0 735342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 649876 0 530657 0 0 0 0 0 0 0 0 0 788185 699228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQIREDIPQVR MGYG000001642_01002;MGYG000000188_00085;MGYG000002919_00610;MGYG000002970_00265;MGYG000003274_00525;MGYG000002775_01392;MGYG000002050_00246;MGYG000003266_00519;MGYG000002961_01431;MGYG000004681_00352;MGYG000000802_00135 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4CXT4@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQIVSQHVAAAPEFC(Carbamidomethyl)YR MGYG000001300_02158 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 896932 0 0 806876 0 0 964383 1081000 1095922 0 0 0 0 441951 377647 0 925694 0 953287 631779 0 0 0 0 597987 852908 1123290 0 0 0 0 0 0 641919 0 650639 944686 0 625148 0 0 999470 0 0 724524 542105 1023580 0 0 0 0 831318 941481 0 850991 0 844001 625740 0 0 0 0 954853 794153 860912 0 0 0 0 0 0 662966 0 725845 719564 0 404016 0 0 647392 0 0 705942 540977 835205 0 0 0 0 0 724566 0 865016 0 362801 585357 0 0 0 0 284733 631666 348187 0 0 0 0 0 0 506950 0 605933 581619 0 513381 0 0 383179 0 0 771942 840260 630670 0 0 0 0 592364 168326 0 156907 0 289954 778705 0 0 0 0 821464 726904 826469 0 0 0 0 0 0 823334 0 1018323 440243 0 457161 0 0 591284 0 0 292961 244717 537315 0 0 0 0 0 0 0 623914 0 0 545136 0 0 0 0 511230 297365 460290 0 0 0 0 0 0 0 0 434559 931152 0 -(Gln->pyro-Glu)QQKPVVVEQVDIIQVQDK MGYG000001313_02966 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia,4AMCZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1109725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1860863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQLSQGTIDKLNESYDLMK MGYG000000164_00292 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,36EW8@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 S 1.0 basic membrane 1.0 tmpC 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 980545 1061850 0 0 924917 0 960520 763204 0 0 0 0 0 0 0 0 875531 0 934019 0 0 0 0 0 0 0 710874 741258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18552888 0 0 0 -(Gln->pyro-Glu)QQNAEAEKR MGYG000002494_03015 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,3ZJ1Q@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 C 1.0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) 1.0 aceF 1.0 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 1.0 2.3.1.12 1.0 ko:K00627 1.0 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 1.0 M00307 1.0 R00209,R02569 1.0 RC00004,RC02742,RC02857 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iETEC_1333.ETEC_0111,iSSON_1240.SSON_0123,iYL1228.KPN_00119 1.0 2-oxoacid_dh,Biotin_lipoyl,E3_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 dihydrolipoyllysine-residue acetyltransferase. transacetylase X. A multimer (24-mer or 60-mer, depending on the source) of this enzyme forms the core of the pyruvate dehydrogenase multienzyme complex, and binds tightly both EC 1.2.4.1 and EC 1.8.1.4.-!-The lipoyl group of this enzyme is reductively acetylated by EC 1.2.4.1, and the only observed direction catalyzed by EC 2.3.1.12 is that where the acetyl group is passed to coenzyme A. acetyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = CoA + N(6)- [(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 543930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQNLDAIHDTVHEMC(Carbamidomethyl)KDEAR MGYG000002438_03105;MGYG000001489_02852;MGYG000000222_03431 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG1592@1|root,COG1592@2|Bacteria,4NJ7V@976|Bacteroidetes,2FP1G@200643|Bacteroidia,22UC5@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Rubrerythrin 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193347 0 0 0 0 0 0 0 0 0 0 260692 0 0 0 0 0 0 0 0 0 0 202621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246495 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 639389 0 0 0 0 0 0 0 0 0 0 652049 0 0 0 0 0 0 -(Gln->pyro-Glu)QQNPVTGSGGMFK MGYG000002926_00666;MGYG000002882_00083;MGYG000002794_00765;MGYG000002156_01166;MGYG000001733_00674;MGYG000002720_00859;MGYG000004196_01675;MGYG000002143_01957;MGYG000004475_00754 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia 0.8888888888888888 186801|Clostridia 1.0 C 0.8888888888888888 alcohol dehydrogenase 0.8888888888888888 kdd 0.8888888888888888 - 1.0 1.4.1.11 0.8888888888888888 ko:K18012 0.8888888888888888 ko00310,map00310 0.8888888888888888 - 0.8888888888888888 R03349 0.8888888888888888 RC00888 0.8888888888888888 ko00000,ko00001,ko01000 0.8888888888888888 - 1.0 - 1.0 - 1.0 ADH_zinc_N 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 Lysine degradation 0.8888888888888888 none 1.0 548474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333374 536081 0 0 0 0 0 0 0 0 0 0 663032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480799 395028 0 0 0 0 0 0 0 0 0 0 498260 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQPELGEKLSPK MGYG000000074_01424 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0578@1|root,COG0578@2|Bacteria,4NEYG@976|Bacteroidetes,2FN2W@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 C-terminal domain of alpha-glycerophosphate oxidase 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,DAO_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358410 0 0 0 0 0 0 0 0 0 0 850331 0 -(Gln->pyro-Glu)QQQELQALQQK MGYG000002478_02506;MGYG000004797_02614;MGYG000002560_00938 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,2FPTR@200643|Bacteroidia,4AMZ6@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 - 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 776129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQQIETLQAELASK MGYG000000243_03188;MGYG000002478_01929;MGYG000004797_03694 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,2FNI1@200643|Bacteroidia,4AVYV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 812105 0 0 0 0 0 0 0 0 0 715454 0 0 0 0 0 0 0 0 252406 0 313520 0 0 0 0 0 0 0 0 801205 0 0 0 0 758461 0 0 344231 0 0 230791 0 0 0 0 0 0 647095 0 0 0 0 0 0 0 0 330732 0 0 0 0 0 0 0 0 0 0 326283 0 0 0 0 250788 0 0 137528 0 0 446539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQQMVQK MGYG000000195_01571;MGYG000001157_00999;MGYG000000084_00625;MGYG000002619_02237;MGYG000001300_00293;MGYG000004732_01390;MGYG000001255_01112;MGYG000002040_01717 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WI1F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 846371 1097606 1480229 1696350 0 499166 974688 1089234 0 1199761 1210156 1151315 1539032 1115204 1432292 603488 0 0 2229659 1861791 0 1183352 803365 930973 1829504 1538827 1173101 1213059 0 768017 853784 691888 1309801 2013998 750408 977036 914730 1124944 1744995 1860648 1605326 1786146 1498086 2134311 2613085 969589 0 518388 1369270 2285294 1813108 2273402 1901455 1453687 0 1373542 3082019 2500167 0 1640296 1586545 2349758 2537854 2236472 2065415 1533734 0 2049842 2531254 2179899 1673005 1747303 669644 1203356 1765953 1807155 0 0 0 570433 0 0 921621 0 0 611348 0 0 0 0 0 0 0 849222 0 0 0 0 667480 581585 0 863564 0 0 0 0 0 626147 0 0 0 0 0 0 0 1236879 2022398 793626 1679592 1417447 1705006 0 0 0 1664106 1863284 1545985 711062 603168 1426559 0 0 1225882 941669 0 1042938 513395 1343601 0 0 0 1353738 0 1034941 1747935 664612 2157484 1056303 0 127927 733362 2153869 0 0 0 206215 261077 0 0 0 0 0 0 281847 0 0 0 0 0 0 0 255909 0 0 0 0 0 0 0 1086599 0 0 0 105748 0 0 0 0 100263 0 -(Gln->pyro-Glu)QQVSLQDVANR MGYG000002478_02149 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,2FNBA@200643|Bacteroidia,4AM82@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EU 1.0 Peptidase, S9A B C family, catalytic domain protein 1.0 dpp 1.0 - 1.0 3.4.14.5 1.0 ko:K01278 1.0 ko04974,map04974 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 1.0 - 1.0 - 1.0 - 1.0 DPPIV_N,PD40,Peptidase_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 dipeptidyl-peptidase IV. Xaa-Pro-dipeptidylaminopeptidase. A membrane-bound serine-type peptidase in mammals.-!-EC 3.4.14.11 catalyzes a similar reaction.-!-Belongs to peptidase family S9B. Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline. 1.0 1.0 1.0 1.0 Protein digestion and absorption 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 584526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 678158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQYTAVKIEK MGYG000001687_00102;MGYG000001310_01505;MGYG000002279_00674;MGYG000001315_03087 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,27VNF@189330|Dorea 0.5 186801|Clostridia 1.0 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 - 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QQYTQVKIEK MGYG000004735_00428 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 - 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 886649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QREELAEQIK MGYG000000018_02208 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus|s__Coprococcus eutactus|m__MGYG000000018 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36F8M@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 formate acetyltransferase 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 729935 0 0 0 0 0 0 0 0 0 414292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QREELAEQIKR MGYG000000018_02208 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus|s__Coprococcus eutactus|m__MGYG000000018 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36F8M@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 formate acetyltransferase 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1652022 0 0 0 0 1015832 0 0 0 0 1653296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103454 0 0 0 0 252809 0 0 0 0 309774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QREELAEQIR MGYG000001315_01877 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25VH6@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QRELNNK MGYG000002438_02216 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,2FUJB@200643|Bacteroidia,22YR4@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uL29 family 1.0 rpmC 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02904 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L29 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 631084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 840414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 229823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1179507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QREQLLEQLTK MGYG000003122_00373;MGYG000002775_00629;MGYG000002970_00844;MGYG000003266_00492;MGYG000002961_01179;MGYG000004681_01377;MGYG000002919_00637;MGYG000001718_00865;MGYG000001636_00787;MGYG000002947_00265;MGYG000001567_01555;MGYG000000188_00058;MGYG000002050_00219;MGYG000001642_00367 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4CW7U@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 integration host factor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 820545 0 0 0 0 0 0 0 0 0 0 0 0 0 540008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285554 0 0 0 0 0 0 0 0 0 0 0 0 0 1339502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QRGDWDQAK MGYG000000198_03565;MGYG000004087_01554;MGYG000002966_00469;MGYG000000255_00860 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,21YYA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein-like domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 944902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 861769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040506 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QRKPGSLGASSYPSR MGYG000000074_01962;MGYG000002082_00487;MGYG000000170_00041;MGYG000000053_00693;MGYG000003539_00291;MGYG000001415_01617 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae 1.0 COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,2FMS5@200643|Bacteroidia,22U9U@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit 1.0 rplC 1.0 - 1.0 - 1.0 ko:K02906 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 179386 0 182242 0 172541 316395 0 0 0 262389 0 0 0 239121 209491 182584 0 0 316327 0 0 0 0 0 198565 0 0 0 0 0 0 0 0 414517 0 0 364417 200849 247391 0 274551 489943 556606 185877 0 175393 0 391706 0 0 0 288310 333235 342687 224758 0 327095 0 271268 0 0 0 255578 0 0 0 0 255862 0 400592 0 283348 0 0 298387 0 368536 0 603885 285558 0 0 0 0 0 256795 0 0 0 0 341813 0 220995 0 216918 0 256446 0 0 0 275522 0 0 0 0 0 0 300234 0 0 0 0 0 194750 541070 0 0 0 0 377660 0 0 0 0 0 0 0 0 0 0 448033 0 418210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1200669 0 0 1730864 1469182 1414663 0 1047790 1309602 1365056 1140556 0 1272111 0 1123217 0 0 0 1681142 1568100 979343 1013012 0 1120725 0 2068946 0 0 0 1525185 0 0 0 0 1795689 0 1838145 0 -(Gln->pyro-Glu)QRPDDFDKDEPVEFPLNR MGYG000001562_01034;MGYG000001546_01498;MGYG000003279_00890;MGYG000001420_00047;MGYG000000003_02437 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,2FNCK@200643|Bacteroidia,22UI6@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 1.0 fklB 1.0 - 1.0 5.2.1.8 1.0 ko:K03772,ko:K03773 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,FKBP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 780216 0 335546 0 334457 945686 679107 0 2056187 0 0 1497766 762414 1192825 0 0 1218391 0 1112885 0 1059599 1372302 0 807641 954758 1128270 1593802 0 773816 2173810 0 0 595579 246305 0 0 1178731 258768 0 0 347014 0 369147 1042589 0 0 361015 0 0 165175 0 335070 0 0 698691 0 0 0 269350 955685 0 0 0 0 0 0 0 368751 0 0 0 0 0 0 0 0 915372 0 1229467 0 1072142 373088 678714 0 1153400 0 0 1061440 597725 1001800 0 0 811149 0 895186 0 1074480 0 0 352895 1018235 868125 810322 0 824041 1413871 0 0 946642 1573268 0 0 767201 1627917 416604 0 415260 0 411424 518432 494152 0 549973 0 0 707408 465067 547206 0 0 427652 0 1545617 0 397852 0 0 478341 1060464 587588 324478 0 508935 431007 0 0 508595 426022 0 0 576342 436263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299252 0 0 0 0 141288 0 0 0 0 0 301032 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QRPGAGSAVSDDEIK MGYG000000243_00735 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG4771@2|Bacteria,4PKE0@976|Bacteroidetes,2G3DW@200643|Bacteroidia,4AME6@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Psort location OuterMembrane, score 10.00 1.0 - 1.0 - 1.0 - 1.0 ko:K02014 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,MipA,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 854417 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1087839 0 0 0 0 1073105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QRPLWASTGTK MGYG000001292_01122;MGYG000003683_00464;MGYG000002459_00838;MGYG000002469_01093 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2046291 0 0 0 0 412711 0 0 0 0 1530223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QRPYDIIADPTVTPK MGYG000000196_03453;MGYG000001345_02362 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,4AK9W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrA 1.0 - 1.0 1.6.5.8 1.0 ko:K00346 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQRA,NQRA_SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 748161 0 0 229845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733004 0 0 662063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281720 0 0 359524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262815 0 0 368987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QRPYDIVAAPLDTPR MGYG000002438_03483 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,22XC8@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrA 1.0 - 1.0 1.6.5.8 1.0 ko:K00346 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQRA,NQRA_SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 344872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 814793 0 0 0 0 0 0 0 0 670127 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QRPYDVIADPTIAPK MGYG000001306_00758 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,4AK9W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrA 1.0 - 1.0 1.6.5.8 1.0 ko:K00346 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQRA,NQRA_SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290413 0 0 0 0 640984 0 0 0 0 512095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QRPYDVIADPTVTPK MGYG000002561_02257;MGYG000001346_03128;MGYG000001313_01399;MGYG000000224_02589 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,4AK9W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrA 1.0 - 1.0 1.6.5.8 1.0 ko:K00346 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQRA,NQRA_SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 741108 0 0 0 0 0 0 789304 0 0 0 0 743855 0 0 0 0 569218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733502 0 0 0 0 0 0 229825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QRVALGR MGYG000003450_00520;MGYG000004022_02346;MGYG000000463_01070;MGYG000002274_02270;MGYG000003166_00269;MGYG000000084_00605;MGYG000003266_01093;MGYG000000131_01048;MGYG000003899_00682;MGYG000000036_00877;MGYG000000352_00466;MGYG000002934_00266;MGYG000003937_00574 domain d__Bacteria 1.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGC7@541000|Ruminococcaceae 0.8461538461538461 186801|Clostridia 0.8461538461538461 P 0.9230769230769231 Belongs to the ABC transporter superfamily 0.8461538461538461 - 0.5384615384615384 - 1.0 - 1.0 ko:K10112 1.0 ko02010,map02010 1.0 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1 1.0 - 1.0 - 1.0 ABC_tran,TOBE,TOBE_2 0.9230769230769231 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QRVAMGR MGYG000000127_05464;MGYG000001310_01635;MGYG000000142_00551;MGYG000000251_02973;MGYG000000312_02369;MGYG000003683_01833;MGYG000000031_00294;MGYG000004271_01581;MGYG000003702_02462;MGYG000000245_00944;MGYG000000002_00989;MGYG000000216_00631;MGYG000002517_01911;MGYG000001338_00540;MGYG000000187_01370;MGYG000002298_01871;MGYG000004733_00020;MGYG000001315_00237;MGYG000002279_00971;MGYG000004296_01406;MGYG000000271_00816;MGYG000000193_03113 domain d__Bacteria 1.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XYK4@572511|Blautia 0.45454545454545453 186801|Clostridia 0.9545454545454546 P 0.9090909090909091 Belongs to the ABC transporter superfamily 0.6363636363636364 ugpC_1 0.9545454545454546 - 1.0 - 0.9545454545454546 ko:K10112 0.9545454545454546 ko02010,map02010 1.0 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 0.9545454545454546 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 0.9545454545454546 3.A.1.1 0.9545454545454546 - 1.0 - 1.0 ABC_tran,TOBE,TOBE_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9545454545454546 0.9545454545454546 0.9545454545454546 0.9545454545454546 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSASDVGNDHR MGYG000002141_00290;MGYG000000217_02029 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,27I8W@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Glutamine synthetase type III N terminal 1.0 glnA 1.0 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 GABAergic synapse;Necroptosis;Glyoxylate and dicarboxylate metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479791 0 0 0 0 379570 0 0 0 0 293666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSC(Carbamidomethyl)EAAVAAIQK MGYG000000196_00720;MGYG000004797_01109;MGYG000003312_00148;MGYG000000098_01819;MGYG000001378_04763;MGYG000000054_01406;MGYG000001313_02680;MGYG000002549_01301;MGYG000003351_01089;MGYG000002560_01042;MGYG000001461_03637;MGYG000002455_02688;MGYG000000105_00820;MGYG000001345_02082;MGYG000003681_01697;MGYG000002171_01456;MGYG000001780_01857;MGYG000002281_01592;MGYG000000243_02393;MGYG000000029_00263 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,2FNGC@200643|Bacteroidia,4AKIZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Belongs to the GHMP kinase family. GalK subfamily 1.0 galK 1.0 - 1.0 2.7.1.6 1.0 ko:K00849 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00554,M00632 1.0 R01092 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 galactokinase. - Part of the Leloir pathway for galactose metabolism.-!-The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine. alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+). 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 540299 602810 938684 526410 456721 579975 656205 0 0 0 574996 0 537172 470234 236814 565617 0 400666 0 614408 558287 529757 494132 726076 657340 594580 754267 425618 585647 0 877298 0 970744 623013 516409 661899 484779 616532 515913 521631 604774 686932 666934 611339 539048 0 0 0 789057 0 602396 624100 641585 589701 0 0 0 296800 374929 443421 262997 513483 582781 347063 532650 0 496900 0 493602 0 445165 508309 0 402254 529801 350146 0 292322 366592 318159 428067 478365 504798 0 0 0 375869 0 134899 0 248764 248543 0 650828 0 292183 446927 280866 351529 0 0 404090 0 191468 376016 0 287380 0 461869 0 0 301327 0 387714 0 0 206144 214481 175609 0 633024 0 0 0 461689 0 389151 0 0 319722 0 277403 0 0 0 511123 0 688035 249269 387953 0 0 0 0 372196 0 397080 148718 281831 256513 390620 372256 359763 0 290928 468031 715183 755407 270097 0 0 0 419132 0 525278 397630 360919 454929 0 757928 0 914249 0 663872 700471 576566 694772 619634 472580 411778 496957 0 521854 0 376385 536668 742671 518658 748044 519570 -(Gln->pyro-Glu)QSC(Carbamidomethyl)EAAVAAIQKK MGYG000000196_00720;MGYG000004797_01109;MGYG000000098_01819;MGYG000001378_04763;MGYG000000054_01406;MGYG000001313_02680;MGYG000002549_01301;MGYG000003351_01089;MGYG000002560_01042;MGYG000002455_02688;MGYG000000105_00820;MGYG000001345_02082;MGYG000003681_01697;MGYG000002171_01456;MGYG000001780_01857;MGYG000002281_01592;MGYG000000243_02393 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,2FNGC@200643|Bacteroidia,4AKIZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Belongs to the GHMP kinase family. GalK subfamily 1.0 galK 1.0 - 1.0 2.7.1.6 1.0 ko:K00849 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00554,M00632 1.0 R01092 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 galactokinase. - Part of the Leloir pathway for galactose metabolism.-!-The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine. alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+). 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 1367923 2405300 2251360 0 2229641 2057067 1897407 2016482 0 2000208 0 2230614 0 1628243 1728427 2539008 2095507 1086972 1680394 0 0 0 1157211 1910946 0 1826715 0 0 2118833 2064873 0 0 2984706 1673971 0 0 1659606 2352757 1752512 1400530 1769970 0 1845139 1473392 1487180 0 0 1834736 2136337 1294154 0 1472244 1477988 1727705 1359176 713331 1601298 0 1277248 1458140 945649 1414012 1570642 0 0 1292702 1571353 1621503 0 0 1784614 0 0 0 1527838 1389623 1155268 1377008 1130552 0 1596255 1232874 1497638 1647040 0 1167350 975796 834282 0 1036146 1092893 1268387 1221406 0 1204090 0 2124404 1064184 0 924614 950227 1206495 0 2958051 1603156 1401334 0 0 381340 1153600 0 0 1186918 1340870 729844 749473 512125 0 860010 575525 739309 0 0 672930 567767 700758 0 594204 714043 464446 423935 359626 367582 0 485548 625305 0 0 925634 627019 0 734011 431498 505496 0 0 617084 428878 0 0 728275 383777 1041608 938674 1284116 0 1508306 1562240 589080 1105211 0 729624 1000517 1092421 0 878164 1135325 1161926 0 1253057 1165789 0 933636 1265920 1115048 1679826 1079150 1539535 0 1103160 512442 1281845 0 0 1055891 1485375 0 0 1467693 1222540 -(Gln->pyro-Glu)QSC(Carbamidomethyl)EAVVAAIKK MGYG000003693_01873 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,2FNGC@200643|Bacteroidia,4AKIZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Belongs to the GHMP kinase family. GalK subfamily 1.0 galK 1.0 - 1.0 2.7.1.6 1.0 ko:K00849 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00554,M00632 1.0 R01092 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 galactokinase. - Part of the Leloir pathway for galactose metabolism.-!-The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine. alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+). 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775830 0 0 0 0 1003908 0 0 0 0 698994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 768642 0 0 0 0 1006698 0 0 0 0 419936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSDC(Carbamidomethyl)NANSSISHEAVR MGYG000001313_02503;MGYG000003681_00913;MGYG000000224_00039 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376527 0 0 0 0 652839 908814 936313 0 0 707886 0 0 0 0 0 460334 0 618937 0 0 870943 0 0 0 0 625640 0 0 401405 0 0 0 872070 0 0 0 0 640045 0 0 0 0 889050 650208 796247 0 0 589691 0 0 0 0 0 1963093 0 555660 0 0 1236801 0 0 0 0 1222895 0 0 1063320 0 0 0 629410 0 0 0 0 0 0 0 0 0 444185 409270 334964 0 0 0 0 0 0 0 0 0 0 369418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSDILAVVK MGYG000000133_00303 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,25X0R@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1140260 1256579 971151 1463129 482229 856898 1415617 961564 896517 1317899 1510836 758574 1840450 2090252 1039387 1209585 1121016 0 826005 0 939270 827705 0 658825 1095510 983151 1411463 0 1680043 0 731365 2090581 1643198 1482679 0 974743 1043177 646636 -(Gln->pyro-Glu)QSEFFLYSKK MGYG000001637_01978;MGYG000002202_01441;MGYG000004719_00689;MGYG000000245_00251;MGYG000000489_00414;MGYG000002517_01550 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 E 1.0 Belongs to the alpha-IPM synthase homocitrate synthase family 0.8333333333333334 - 1.0 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 iHN637.CLJU_RS03250 1.0 HMGL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSETAAVEIKR MGYG000002494_02854 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3WXSN@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 NT 1.0 Homologues of the ligand binding domain of Tar 1.0 tsr 1.0 GO:0001101,GO:0001932,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0006935,GO:0007154,GO:0007165,GO:0007172,GO:0008104,GO:0008150,GO:0009593,GO:0009605,GO:0009719,GO:0009966,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0023051,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031399,GO:0032101,GO:0032110,GO:0032268,GO:0032879,GO:0032991,GO:0033036,GO:0034613,GO:0034622,GO:0038023,GO:0040011,GO:0040012,GO:0042221,GO:0042325,GO:0042330,GO:0042802,GO:0042803,GO:0043113,GO:0043200,GO:0043424,GO:0043549,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0046983,GO:0048583,GO:0048870,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051174,GO:0051179,GO:0051246,GO:0051259,GO:0051260,GO:0051270,GO:0051338,GO:0051606,GO:0051641,GO:0051668,GO:0051674,GO:0051716,GO:0060089,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0070727,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071840,GO:0071944,GO:0072657,GO:0080090,GO:0098561,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902021,GO:2000145 1.0 - 1.0 ko:K03406,ko:K05874,ko:K05875,ko:K05876,ko:K05877 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 4HB_MCP_1,HAMP,MCPsignal,TarH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 784058 841204 821624 566241 0 1172302 884728 0 0 1182326 0 0 0 895877 0 0 944259 0 977333 0 959851 1288041 0 1182544 832547 727966 631554 0 892255 825704 0 0 848963 0 0 0 662191 614748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSEYASQLKEK MGYG000001300_02187;MGYG000003899_00641 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 402191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463614 0 0 0 589671 0 0 0 0 0 0 0 0 0 452406 0 437053 0 0 0 0 0 0 0 356044 0 0 0 0 0 373231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSFYAAFYK MGYG000000243_00718;MGYG000003351_03535;MGYG000003367_02308;MGYG000002561_01067;MGYG000002549_02853;MGYG000001661_03082;MGYG000002717_01899;MGYG000002455_00013;MGYG000000224_01788;MGYG000000196_04182;MGYG000001337_03773;MGYG000004824_01681;MGYG000004899_00369;MGYG000002171_00434;MGYG000003363_01242;MGYG000001345_00362;MGYG000000098_00764;MGYG000002478_02176;MGYG000001346_02491 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2207@1|root,COG2207@2|Bacteria,4NVK3@976|Bacteroidetes,2FRSW@200643|Bacteroidia,4AN3S@815|Bacteroidaceae 0.7368421052631579 976|Bacteroidetes 1.0 K 0.7894736842105263 transcriptional regulator (AraC 0.7368421052631579 - 1.0 - 1.0 - 0.7894736842105263 - 0.7894736842105263 - 1.0 - 1.0 - 1.0 - 1.0 - 0.7894736842105263 - 1.0 - 1.0 - 1.0 HTH_18,TPR_8 0.7894736842105263 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.7894736842105263 0.7894736842105263 0.7894736842105263 0.7894736842105263 1.0 none 1.0 196111 0 218641 203372 274771 153150 213492 261173 0 0 243574 204765 0 0 0 0 281948 0 0 0 339822 248982 0 298207 276640 327760 0 0 301779 266726 431029 0 429190 210471 347235 131807 73900 369086 228055 0 392972 411418 526463 485292 483475 752346 0 0 614640 617083 0 0 0 0 456396 0 0 0 515670 435090 0 361339 210986 337641 0 0 410030 495496 263529 0 227196 516054 501694 397506 314232 469694 0 0 93887 99939 127422 247390 124500 0 0 0 260488 267046 0 0 0 0 110138 0 0 0 173139 183815 0 135448 174547 97145 0 0 261359 201590 285179 0 143035 108806 173522 188255 71436 192049 53454 0 0 0 0 0 0 62473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 69904 0 0 0 0 0 0 0 0 0 62378 0 0 72360 0 71817 0 224445 254548 230594 44548 0 0 240015 189065 0 0 0 0 89584 0 0 0 168747 0 0 255613 179146 181809 0 0 60040 180855 3058 0 72405 0 0 0 0 3447 -(Gln->pyro-Glu)QSGGHGQYGHVK MGYG000004733_01898;MGYG000000251_02148;MGYG000000249_00677;MGYG000000002_01361;MGYG000000404_01392;MGYG000002298_01791;MGYG000004735_01956;MGYG000002025_01499;MGYG000000142_02369;MGYG000002492_01806;MGYG000002772_00739;MGYG000000271_00034;MGYG000002835_01987;MGYG000000154_00745;MGYG000002202_01144;MGYG000000095_04309;MGYG000000171_00253;MGYG000004271_00377;MGYG000001338_01579;MGYG000000164_00435;MGYG000002517_01557;MGYG000000201_01853;MGYG000002966_02309;MGYG000002279_00268;MGYG000000133_01852;MGYG000000212_00731 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3XZ5X@572511|Blautia 0.38461538461538464 186801|Clostridia 1.0 J 1.0 translation elongation factor G 0.38461538461538464 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 683783 0 702973 1000471 913424 0 0 0 0 0 1814144 0 0 0 0 629833 0 0 0 0 1166264 0 633131 0 0 0 0 625206 0 0 0 0 0 0 0 0 0 0 603733 0 469311 782985 488259 0 0 0 0 0 693072 0 0 0 0 560593 0 0 0 0 1030028 0 576587 0 0 0 0 502286 0 0 0 0 0 0 0 0 0 0 273898 0 408077 460056 137586 0 0 0 0 0 0 0 0 0 0 702188 0 0 0 0 1214934 0 644545 0 0 0 0 598067 0 0 0 0 0 0 0 0 0 0 308631 0 323215 348506 326150 0 0 0 0 0 364722 0 0 0 0 35240 0 0 0 0 523572 0 382210 0 0 0 0 194486 0 0 0 0 0 0 0 0 0 0 48288 0 675440 771609 641087 0 0 0 0 0 258559 0 0 0 0 421362 0 0 0 0 437451 0 67265 0 0 0 0 413901 0 0 0 -(Gln->pyro-Glu)QSGGKGQYGHVK MGYG000002040_01211;MGYG000003937_01028;MGYG000003450_00444;MGYG000000084_01999;MGYG000001300_00281;MGYG000000436_01219 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.8333333333333334 186801|Clostridia 0.8333333333333334 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 715347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1033585 0 1038986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319080 0 483356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 942075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 672786 0 543727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSGGRGQYGHC(Carbamidomethyl)K MGYG000001615_01715;MGYG000002279_01931;MGYG000000171_02843;MGYG000000201_03874;MGYG000000417_00151;MGYG000004735_00885;MGYG000002966_00551;MGYG000001688_04230;MGYG000000271_03364;MGYG000000038_00759;MGYG000001367_00668;MGYG000001315_01206;MGYG000003702_00714;MGYG000000133_02992;MGYG000000262_00029;MGYG000001707_01475;MGYG000001379_00688;MGYG000000198_01164;MGYG000001310_01964;MGYG000002528_01099;MGYG000000562_01882;MGYG000000179_00921;MGYG000000216_02407;MGYG000003381_01598;MGYG000002517_00204;MGYG000000177_01045;MGYG000002298_03446;MGYG000004296_01667;MGYG000001637_00070;MGYG000003366_00387;MGYG000001338_03374;MGYG000000142_00172;MGYG000000251_00063;MGYG000000233_00808;MGYG000000200_01983;MGYG000000050_01748;MGYG000000146_01349;MGYG000000255_02008;MGYG000004891_02430;MGYG000004087_00550;MGYG000000164_01097;MGYG000004642_00845;MGYG000000212_03312;MGYG000000187_02028;MGYG000000154_02190;MGYG000002946_01538;MGYG000004285_00598;MGYG000004271_02230;MGYG000002212_00197;MGYG000000002_03595;MGYG000001617_01407;MGYG000003355_03290;MGYG000004733_01212 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.33962264150943394 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 0.9811320754716981 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 591855 124757 0 0 0 0 0 327836 362573 0 0 0 208353 0 0 0 421308 227924 0 0 0 0 0 0 0 0 0 0 0 308796 289698 0 0 0 0 225363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228079 62718 0 0 0 0 0 127261 146504 0 0 0 103480 0 0 0 115419 127153 0 0 0 0 0 0 0 0 0 0 0 319281 255713 0 0 0 0 0 0 0 187023 295674 0 0 0 0 0 205499 114739 0 0 0 356084 0 0 0 370894 177596 0 0 0 0 0 0 0 0 0 0 0 289751 141890 0 0 0 0 145002 0 0 441100 446561 0 0 0 0 0 483688 373397 0 0 0 147410 0 0 0 81849 0 0 0 0 0 0 0 0 0 0 0 0 324697 628813 0 0 0 0 343259 -(Gln->pyro-Glu)QSHQEMLDHVEGLLK MGYG000004797_00953;MGYG000002478_04065 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,2FN99@200643|Bacteroidia,4AK72@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Psort location Cytoplasmic, score 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291057 0 0 0 0 526314 0 0 0 0 399068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 506824 0 0 0 0 423742 0 0 0 0 321052 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSIAKEDALKK MGYG000002478_04502;MGYG000004797_02455 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,2FMAU@200643|Bacteroidia,4AMPD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSINGATN(Deamidated)PYYYAPIR MGYG000002082_00620 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900544265|m__MGYG000002082 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124629 0 226725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16884039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16914493 0 17938272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSIPLANAMR MGYG000002438_00646 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG3291@1|root,COG3291@2|Bacteria,4PMYH@976|Bacteroidetes,2G0KU@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Domain of Unknown Function (DUF1080) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1080 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269708 0 0 0 0 0 0 0 0 0 0 0 0 0 653621 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSITIPAKR MGYG000002455_01438 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia,4ARQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1922312 0 0 0 0 1579565 0 0 0 0 1183361 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSKQPLQR MGYG000002494_03339 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2376@1|root,COG2376@2|Bacteria,1MVSR@1224|Proteobacteria,1RNRQ@1236|Gammaproteobacteria,3WVUW@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Dak1 domain 1.0 dhaK 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 1.0 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 1.0 ko:K00863,ko:K05878 1.0 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 1.0 M00344 1.0 R01011,R01012,R01059 1.0 RC00002,RC00015,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 1.0 Dak1,Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. | triokinase. | glycerone kinase. | FAD-AMP lyase (cyclizing). triose kinase. | dihydroxyacetone kinase. | FMN cyclase. While FAD was the best substrate tested the enzyme also splits ribonucleoside diphosphate-X compounds in which X is an acyclic or cyclic monosaccharide or derivative bearing an X-OH group that is able to attack internally the proximal phosphorus with the geometry necessary to form a P=X product; either a five-atom monocyclic phosphodiester or a cis-bicyclic phosphodiester-pyranose fusion.-!-The reaction is strongly inhibited by ADP or ATP but is unaffected by the presence of the product, cFMN. dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. | ATP + D-glyceraldehyde = ADP + D-glyceraldehyde 3-phosphate + H(+). | ATP + dihydroxyacetone = ADP + dihydroxyacetone phosphate + H(+). | FAD = AMP + H(+) + riboflavin cyclic-4',5'-phosphate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RIG-I-like receptor signaling pathway;Glycerolipid metabolism;Metabolic pathways;Fructose and mannose metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 833798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 983343 0 691330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSLSPSTQWEWNK MGYG000001783_01400;MGYG000003693_03081 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 535728 0 0 0 0 1723088 0 0 0 0 928714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407856 0 0 0 0 287474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSNYNFSTGDLR MGYG000001346_03588 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 2DUCV@1|root,33Q16@2|Bacteria,4PMVT@976|Bacteroidetes,2G0IH@200643|Bacteroidia,4AV8P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1039391 410586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289649 397565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 776399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSPITNLAR MGYG000000271_03295;MGYG000000164_01128;MGYG000002517_00193;MGYG000000179_05049;MGYG000002279_01915;MGYG000004271_02223;MGYG000000198_05827;MGYG000000038_00775 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia 0.375 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 465599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1320148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSPNDPNSVWKK MGYG000000217_03304 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Acetatifactor|s__Acetatifactor sp900066565|m__MGYG000000217 1.0 COG1653@1|root,COG1653@2|Bacteria,1TW09@1239|Firmicutes,24BZW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 transport 1.0 - 1.0 - 1.0 - 1.0 ko:K02027,ko:K17318 1.0 ko02010,map02010 1.0 M00207,M00603 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1,3.A.1.1.29,3.A.1.1.9 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359720 0 0 0 0 554721 0 0 0 0 806343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSPQVLNLPFKEGISR MGYG000000133_00308 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3XYNE@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 8.87 1.0 purH 1.0 - 1.0 2.1.2.3,3.5.4.10 1.0 ko:K00602 1.0 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 1.0 M00048 1.0 R01127,R04560 1.0 RC00026,RC00263,RC00456 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 AICARFT_IMPCHas 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylaminoimidazolecarboxamide formyltransferase. | IMP cyclohydrolase. aminoimidazolecarboxamide ribonucleotide transformylase. | inosinicase. - (6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. | H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. 1.0 1.0 1.0 1.0 Antifolate resistance;Metabolic pathways;One carbon pool by folate;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530771 985667 0 0 401368 0 0 492773 596988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 414939 740379 1320255 0 0 0 0 606628 -(Gln->pyro-Glu)QSPQVLSLPFKPGIK MGYG000002517_01952 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Bifunctional purine biosynthesis protein PurH 1.0 purH 1.0 - 1.0 2.1.2.3,3.5.4.10 1.0 ko:K00602 1.0 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 1.0 M00048 1.0 R01127,R04560 1.0 RC00026,RC00263,RC00456 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 AICARFT_IMPCHas 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylaminoimidazolecarboxamide formyltransferase. | IMP cyclohydrolase. aminoimidazolecarboxamide ribonucleotide transformylase. | inosinicase. - (6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. | H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. 1.0 1.0 1.0 1.0 Antifolate resistance;Metabolic pathways;One carbon pool by folate;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541970 0 0 0 0 0 0 0 0 1276800 0 0 0 0 1127460 0 934482 0 0 0 0 0 0 0 933709 1009510 946820 0 0 0 0 0 0 0 0 916073 1370953 0 -(Gln->pyro-Glu)QSPSVILIDTTVIANAPVR MGYG000004717_01070;MGYG000002966_00993 domain d__Bacteria 1.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,4H3R3@909932|Negativicutes 0.5 909932|Negativicutes 0.5 C 1.0 Iron-containing alcohol dehydrogenase 0.5 - 0.5 - 1.0 1.1.1.6 1.0 ko:K00005 1.0 ko00561,ko00640,ko01100,map00561,map00640,map01100 1.0 - 1.0 R01034,R10715,R10717 1.0 RC00029,RC00117,RC00670 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol dehydrogenase. NAD-linked glycerol dehydrogenase. Also acts on 1,2-propanediol. glycerol + NAD(+) = dihydroxyacetone + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35854663 0 0 17416101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14468689 0 38700444 0 0 0 0 0 0 0 0 43620611 0 0 0 0 26237042 -(Gln->pyro-Glu)QSQEEMGHAYAMADYIIKR MGYG000000013_01582;MGYG000001345_00719;MGYG000002549_02437;MGYG000000196_02859;MGYG000001378_01746 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,2FQD1@200643|Bacteroidia,4AP5J@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Iron-storage protein 1.0 ftnA 1.0 - 1.0 1.16.3.2 1.0 ko:K02217 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ferritin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 bacterial non-heme ferritin. - Ferritins are intracellular iron-storage and detoxification proteins found in all kingdoms of life.-!-They are formed from two subunits that coassemble in various ratios to form a spherical protein shell.-!-Thousands of mineralized iron atoms are stored within the core of the structure.-!-The product of dioxygen reduction by the bacterial non-heme ferritin is hydrogen peroxide, which is consumed in a subsequent reaction. 4 Fe(2+) + 6 H2O + O2 = 12 H(+) + 4 iron(III) oxide-hydroxide. 1.0 1.0 1.0 1.0 1.0 none 1.0 570975 576015 0 0 0 0 0 0 0 0 610274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478554 0 0 0 0 0 0 0 0 724255 423855 517249 0 1557753 672673 0 0 0 0 0 0 0 0 1797586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 950061 0 0 0 0 0 0 0 0 1545762 973907 2206175 0 415062 0 0 0 0 0 0 0 0 0 191596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161570 0 0 0 0 0 0 0 0 0 182413 0 0 382271 474510 0 0 0 0 0 0 0 0 483012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331530 0 0 0 0 0 0 0 0 863299 396731 779191 0 12168 292860 0 0 0 0 0 0 0 0 1048501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3298447 0 0 0 0 0 0 0 0 0 8880 19274 0 -(Gln->pyro-Glu)QSQGVAIAYDSR MGYG000000133_00139;MGYG000003821_00787;MGYG000003012_01663 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 pgcA 1.0 - 1.0 5.4.2.2,5.4.2.8 1.0 ko:K01835,ko:K01840 1.0 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00114,M00549 1.0 R00959,R01057,R01818,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Alpha-amylase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). | phosphomannomutase. phosphoglucose mutase. | phosphomannose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. | alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. | alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 134009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518309 0 0 656023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 749312 0 0 0 0 381881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733560 0 0 0 0 994258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340489 0 0 0 0 0 -(Gln->pyro-Glu)QSQISGHVTSSEDGSPVIGASIK MGYG000003697_00736 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2G3FU@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2170372 0 1101481 1737858 0 0 0 0 1559359 0 1461582 0 0 1075489 0 3346911 0 0 0 2154195 5396605 1500365 0 0 0 2300507 0 0 0 0 1584594 0 0 0 0 1680994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSSDQKELALK MGYG000000003_02214 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG5010@1|root,COG5010@2|Bacteria 1.0 2|Bacteria 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2.7.11.1 1.0 ko:K14949 1.0 ko05152,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01001 1.0 - 1.0 - 1.0 - 1.0 AAT,DUF3868,Glyco_trans_1_2,Glyco_transf_4,Glycos_transf_2,MecA_N,Methyltransf_23,OmpA,PMT_2,Pkinase,PknG_TPR,PknG_rubred,SPOR,Sulfotransfer_3,TPR_11,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8,UnbV_ASPIC,VCBS,gag-asp_proteas 1.0 - 1.0 - 1.0 - 1.0 - 1.0 non-specific serine/threonine protein kinase. threonine-specific protein kinase. This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.-!-Formerly EC 2.7.1.37 and EC 2.7.1.70. (1) ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]. (2) ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl- [protein]. 1.0 1.0 1.0 1.0 Tuberculosis 1.0 none 1.0 0 0 0 0 0 0 606945 0 688424 0 0 0 0 0 0 0 0 0 1058031 0 899633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSSGAPGASSQIIIR MGYG000001313_01935;MGYG000004479_01491;MGYG000001783_00567 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG3188@1|root,COG1629@2|Bacteria,COG3188@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4ANM7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 NPU 1.0 Psort location OuterMembrane, score 9.49 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 698371 0 0 0 0 0 0 0 0 0 0 1679901 0 0 0 0 1542291 0 0 0 0 1450441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596648 0 0 0 0 0 0 0 0 0 1168533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSSGAPGASSQIVIR MGYG000003363_02129;MGYG000003681_00347 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1629@1|root,COG3188@1|root,COG1629@2|Bacteria,COG3188@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4ANM7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 NPU 1.0 Psort location OuterMembrane, score 9.49 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459958 0 0 0 0 0 0 724186 708628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572494 781737 0 0 0 0 0 0 0 0 0 0 492966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSTHAQEC(Carbamidomethyl)VSK MGYG000002517_02716 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia 1.0 186801|Clostridia 1.0 NT 1.0 methyl-accepting chemotaxis protein 1.0 - 1.0 - 1.0 - 1.0 ko:K03406 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 HAMP,MCPsignal,dCache_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656477 523401 0 0 0 0 0 0 0 0 0 0 553097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168574 0 0 0 0 0 0 0 0 0 0 393336 0 -(Gln->pyro-Glu)QSVAQYVAQVAK MGYG000000233_01317;MGYG000000205_00610;MGYG000000274_02582;MGYG000000251_01122;MGYG000000194_00522;MGYG000000278_03744;MGYG000004735_00873;MGYG000000255_00470;MGYG000002445_00993 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,21ZJJ@1506553|Lachnoclostridium 0.7777777777777778 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 182833 96442 0 0 0 0 0 0 0 324679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 148391 0 0 0 0 0 0 0 216330 446231 0 0 0 0 0 0 0 540284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 233693 0 0 0 0 144408 0 0 131787 129808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288353 0 0 0 0 79797 -(Gln->pyro-Glu)QSVDDIHK MGYG000000074_01707;MGYG000002082_02076 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,22U6H@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Fumarate reductase flavoprotein C-term 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 883647 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSVDDIHKK MGYG000002203_00448;MGYG000001546_01596;MGYG000004006_00370;MGYG000000003_02554;MGYG000001302.1_00465;MGYG000001663_00888;MGYG000001420_00223;MGYG000000074_01707;MGYG000001415_01060;MGYG000002082_02076 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,22U6H@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Fumarate reductase flavoprotein C-term 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 292269 287909 0 0 0 0 0 277766 0 0 0 0 0 0 0 0 462045 459696 0 0 0 0 0 0 0 0 0 644999 324233 0 264594 0 341036 0 0 311115 0 0 244482 328045 0 0 0 0 0 289731 0 0 0 0 0 0 0 0 315807 362288 0 0 0 0 0 0 0 0 0 185721 133997 0 129965 0 323690 0 0 298740 0 0 456996 294064 0 0 0 0 0 289954 0 0 0 0 0 0 0 0 183675 443246 0 0 0 0 0 0 0 0 0 416658 238855 0 256885 0 337604 0 0 238453 0 0 349885 240968 0 0 0 0 0 394690 0 0 0 0 0 0 0 0 666503 310130 0 0 0 0 0 0 0 0 0 340972 290964 0 395033 0 288020 0 0 332679 0 0 610404 890683 0 0 0 0 0 713317 0 0 0 0 0 0 0 0 949755 983219 0 0 0 0 0 0 0 0 0 838335 534389 0 642521 0 1240248 0 0 725731 -(Gln->pyro-Glu)QSVDEQFYSYIRPQETGNKTDIR MGYG000000243_02704 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,2FM0P@200643|Bacteroidia,4AKD1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG3250 Beta-galactosidase beta-glucuronidase 1.0 lacZ 1.0 - 1.0 3.2.1.23 1.0 ko:K01190 1.0 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 1.0 - 1.0 R01105,R01678,R03355,R04783,R06114 1.0 RC00049,RC00452 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N 1.0 3.2.1.23 1.0 GH2 1.0 GH2 1.0 GH2 1.0 beta-galactosidase. lactase. Some enzymes in this group hydrolyze alpha-L-arabinosides; some animal enzymes also hydrolyze beta-D-fucosides and beta-D-glucosides (cf. EC 3.2.1.108). Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D- galactosides. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Other glycan degradation;Sphingolipid metabolism 1.0 none 1.0 0 0 525074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318352 0 0 0 0 518450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSVDQPVQTGYK MGYG000002323_04217;MGYG000000093_05346;MGYG000002366_00008;MGYG000002515_03905;MGYG000002385_03599;MGYG000002494_02406;MGYG000002506_03404 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,3XP3D@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 iSbBS512_1146.SbBS512_E4187 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 404243 0 0 0 378067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292054 0 361351 0 0 0 0 0 287401 0 0 418844 0 0 0 0 0 0 0 1385498 0 1209975 1666341 1240227 0 960034 1193883 0 0 0 0 0 0 1447215 0 1516136 0 0 2053409 0 1411926 0 0 0 0 2524270 2023014 0 0 1072935 0 0 0 0 840428 0 0 0 0 410281 968677 445532 0 321588 383388 0 0 0 0 0 0 388516 0 0 0 0 909666 0 703900 0 0 0 0 0 516270 0 0 415189 0 0 0 0 326757 0 0 0 0 270071 343278 0 0 0 0 0 0 0 0 0 0 308653 0 0 0 0 544334 0 524322 0 0 0 0 981771 0 0 0 478734 0 0 0 0 581100 0 0 0 0 0 291202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSVIGIGEALFDVLPEGK MGYG000003697_02156 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0524@1|root,COG0524@2|Bacteria,4NGFK@976|Bacteroidetes,2FN72@200643|Bacteroidia,22WT2@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 pfkB family 1.0 ydjH_1 1.0 - 1.0 2.7.1.4 1.0 ko:K00847 1.0 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 1.0 - 1.0 R00760,R00867,R03920 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructokinase. D-fructokinase. - ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways;Fructose and mannose metabolism;Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2093976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3467226 0 0 3452588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7996399 0 3852263 0 0 0 0 0 0 0 0 1597500 0 0 0 0 3154733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4042909 0 0 0 0 0 -(Gln->pyro-Glu)QSVLNVIDGK MGYG000003279_01900 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900541585|m__MGYG000003279 1.0 COG5010@1|root,COG5010@2|Bacteria 1.0 2|Bacteria 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2.7.11.1 1.0 ko:K14949 1.0 ko05152,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01001 1.0 - 1.0 - 1.0 - 1.0 AAT,DUF3868,Glyco_trans_1_2,Glyco_transf_4,Glycos_transf_2,MecA_N,Methyltransf_23,OmpA,PMT_2,Pkinase,PknG_TPR,PknG_rubred,SPOR,Sulfotransfer_3,TPR_11,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8,UnbV_ASPIC,VCBS,gag-asp_proteas 1.0 - 1.0 - 1.0 - 1.0 - 1.0 non-specific serine/threonine protein kinase. threonine-specific protein kinase. This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.-!-Formerly EC 2.7.1.37 and EC 2.7.1.70. (1) ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]. (2) ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl- [protein]. 1.0 1.0 1.0 1.0 Tuberculosis 1.0 none 1.0 639293 0 0 0 0 0 680624 0 0 0 0 0 0 0 0 0 0 0 0 817247 0 0 0 0 528703 615738 0 0 591546 0 0 0 0 0 0 0 572023 0 0 0 0 0 0 0 70595 0 0 0 0 0 0 0 0 0 0 0 0 72584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 58111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QSYDETTNATFYSPMR MGYG000001346_03589 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 540840 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1109337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTAAYGHFGR MGYG000001688_00425;MGYG000002946_01647;MGYG000000146_01355;MGYG000001199_03286;MGYG000002312_03155;MGYG000002772_00452;MGYG000001141_02243;MGYG000004691_01096;MGYG000003074_01494;MGYG000000143_02413;MGYG000002393_02449;MGYG000001577_00680;MGYG000000142_00387;MGYG000002286_02226;MGYG000000087_01173;MGYG000003819_01446;MGYG000001531_00352;MGYG000003063_01146;MGYG000002989_01957;MGYG000000200_02586;MGYG000000323_01801;MGYG000001496_01620;MGYG000000164_01248;MGYG000002212_00029;MGYG000000206_02668;MGYG000000268_02165;MGYG000002492_00420;MGYG000000202_00319;MGYG000001683_00544;MGYG000002517_00444;MGYG000000252_02776;MGYG000002298_01200;MGYG000000198_05052;MGYG000000212_03221;MGYG000000242_02254;MGYG000004519_00378;MGYG000000133_01435;MGYG000000806_00731;MGYG000000127_01128 domain d__Bacteria 1.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3XZ7D@572511|Blautia 0.2564102564102564 186801|Clostridia 0.9487179487179487 H 1.0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme 1.0 metK 1.0 - 0.9743589743589743 2.5.1.6 0.9743589743589743 ko:K00789 0.9743589743589743 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 0.9743589743589743 M00034,M00035,M00368,M00609 0.9743589743589743 R00177,R04771 0.9743589743589743 RC00021,RC01211 0.9743589743589743 ko00000,ko00001,ko00002,ko01000 0.9743589743589743 - 1.0 - 1.0 - 1.0 S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N,YgbB 0.9487179487179487 - 1.0 - 1.0 - 1.0 - 0.8974358974358975 methionine adenosyltransferase. S-adenosylmethionine synthetase. Formerly EC 2.4.2.13. ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L- methionine. 0.9743589743589743 0.9743589743589743 0.9743589743589743 0.9743589743589743 Biosynthesis of amino acids;Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 0.9743589743589743 none 1.0 1453457 1353453 752398 0 0 1047345 703806 1104001 0 0 1142603 0 1491210 1054359 0 1737729 0 476525 1058670 0 1420990 1377791 849138 945321 0 1095575 1019747 1049066 1555050 0 642750 0 844347 0 1459707 1509784 1145968 771753 203055 376444 0 0 0 0 235142 522473 0 0 747291 0 0 526716 0 0 0 0 0 0 0 0 365131 301777 0 475066 801845 0 248499 0 1859437 0 0 0 0 469137 0 0 0 1570749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356802 0 0 0 662671 0 0 0 0 174514 662612 0 0 0 0 0 0 0 513383 462941 1244520 538943 0 0 0 366058 414920 851509 0 0 161614 0 644340 1021847 0 345993 0 0 560481 0 743787 138569 0 0 0 963298 1454529 0 628575 0 549748 0 182152 0 927381 927360 825649 0 813421 741647 0 0 0 697573 0 1200762 0 0 1867724 0 1192427 2789965 0 3307338 0 483012 1913100 0 1728998 2844222 939507 2500301 0 1692705 2436106 954286 0 0 1381845 0 4461800 0 1783689 2281712 2013089 3194802 -(Gln->pyro-Glu)QTAEGALNEAHSILQR MGYG000004271_01770;MGYG000000271_01499;MGYG000000404_00502;MGYG000002492_02952 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.5 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 4077745 3633413 2468114 4682823 3517319 4064203 4753604 4921824 5868830 5923190 8835161 8601868 5622799 6342543 4831510 0 5627111 0 3933311 2186819 3483643 2917558 0 3928206 5223668 4476024 4149698 0 4884483 9905993 3298842 3263883 2295530 6185491 4437723 3760505 5447976 2072458 222645 131659 221201 0 109038 0 267681 0 0 0 362139 604674 0 0 0 0 277683 0 225524 0 0 0 0 0 0 0 0 0 0 342513 257800 0 224467 228535 0 0 154358 0 0 215045 0 0 0 0 0 0 0 0 0 0 0 0 388445 0 0 0 0 229022 0 394162 0 0 0 0 0 0 193543 0 0 435884 0 0 0 0 0 0 296869 336755 273171 0 0 0 330929 0 0 338251 0 541284 0 0 156097 0 307261 0 0 411160 0 0 0 0 0 0 0 0 0 0 553370 367129 950763 0 622611 0 0 290109 0 348729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277258 0 0 0 0 0 0 0 0 0 338272 543274 0 0 0 0 0 218036 -(Gln->pyro-Glu)QTAEGSLNEINNNLQR MGYG000002494_03500 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,3X1YU@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 fliC 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1044904 0 0 1959733 1286758 1340174 956996 1305568 0 0 0 0 0 0 1229537 0 1544127 0 1055001 1485945 0 1830383 0 0 0 0 1112052 1403463 0 0 1246759 0 0 0 0 397367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTAENAYTEHVEK MGYG000000243_02459 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 2EZ6G@1|root,33SCG@2|Bacteria,4P1BR@976|Bacteroidetes,2FN2M@200643|Bacteroidia,4AMWX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG27649 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4488 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1723240 0 943973 0 0 0 0 0 0 0 1082440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1764100 0 0 0 0 1506161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575758 0 584401 0 0 0 0 0 0 0 836623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTAFSQYDRPQAR MGYG000002323_02346;MGYG000000093_03243;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206;MGYG000002534_02768;MGYG000001692_01757 order d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.8571428571428571 1236|Gammaproteobacteria 0.8571428571428571 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.8571428571428571 adhE 0.8571428571428571 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 0.8571428571428571 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 0.8571428571428571 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 276628 921121 1497609 1042498 1776764 1953759 253547 0 1149548 1690560 0 1306543 0 2313539 0 0 314164 0 1730437 193772 474941 2013738 0 2030864 1722523 1880538 1332931 0 1261470 1482350 0 1431159 297079 195597 1407854 1098463 580242 1190505 9928074 12840505 14815997 10731068 12174075 19189037 12653291 0 11725144 14608207 0 7867618 0 11840692 0 0 15441776 0 15812364 10205335 12282158 20516371 0 17465000 13562155 11674105 8977728 0 19037396 15937676 0 8261650 17150117 10946793 8243315 8723448 9793252 11269266 0 668791 512272 435045 480522 2536191 658668 0 0 522088 0 391230 0 0 0 0 431581 0 505187 0 0 2226623 0 1932111 549183 354224 518795 0 573326 170316 0 966628 1162164 1405433 646433 360671 270190 781697 1775812 2332698 2843646 2279188 2621812 2444674 1727260 0 2212537 3271802 0 2234605 0 2403563 0 0 2708456 0 2934075 604875 600528 2239283 0 2327502 2387387 806377 2641106 0 3114203 2424021 0 2602531 2975989 1779333 2724055 2236737 2006647 3304270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222722 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTAITEKFPNR MGYG000002438_02210 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,2FT3A@200643|Bacteroidia,22YD1@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome 1.0 rplW 1.0 - 1.0 - 1.0 ko:K02892 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 945355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1216732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTANSDVVVITSGIPR MGYG000002281_00044;MGYG000001337_04178;MGYG000000074_00796;MGYG000002549_00073;MGYG000000236_02903;MGYG000000098_01921;MGYG000001345_01394;MGYG000000196_04123;MGYG000001302.1_02054;MGYG000003922_03477;MGYG000003546_00282;MGYG000001378_03171 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,2FM7E@200643|Bacteroidia,4ANBW@815|Bacteroidaceae 0.8333333333333334 976|Bacteroidetes 1.0 C 1.0 Catalyzes the reversible oxidation of malate to oxaloacetate 1.0 mdh 1.0 - 1.0 1.1.1.37 1.0 ko:K00024 1.0 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 1.0 R00342,R07136 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ldh_1_C,Ldh_1_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 malate dehydrogenase. malic dehydrogenase. Also oxidizes some other 2-hydroxydicarboxylic acids. (S)-malate + NAD(+) = H(+) + NADH + oxaloacetate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Citrate cycle (TCA cycle);Glyoxylate and dicarboxylate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Cysteine and methionine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 447577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255085 0 188473 0 0 0 181960 479612 0 0 0 0 0 0 0 0 0 0 0 0 510449 0 0 0 0 262091 0 293658 0 0 0 325294 0 0 0 0 0 0 272692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 773883 0 0 0 1059933 784888 0 0 0 0 0 0 0 0 0 0 0 0 1643630 0 0 225984 0 815874 0 1173017 0 0 0 1371177 0 0 0 0 0 0 976092 0 -(Gln->pyro-Glu)QTAPNAYTEHVEK MGYG000002478_01733;MGYG000001787_02387;MGYG000004797_01424 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2EZ6G@1|root,33SCG@2|Bacteria,4P1BR@976|Bacteroidetes,2FN2M@200643|Bacteroidia,4AMWX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG27649 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4488 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 334653 0 757745 758485 823888 520719 0 0 0 367573 0 690177 1457852 0 0 1262763 0 741523 0 714571 0 608197 556907 311622 0 576062 0 563905 590095 275839 0 0 627369 0 0 604266 595271 417327 868246 0 806335 847396 1109385 626202 0 546175 0 895873 0 659010 1327721 0 0 1379050 0 0 0 783880 0 476845 334933 256325 0 777887 0 234899 643159 616397 0 0 654842 0 0 642169 606536 704874 174929 0 523509 0 527591 0 0 0 0 0 0 339363 668783 0 0 677543 0 549103 0 265193 0 0 352456 324697 0 0 0 473575 166995 295200 0 0 0 0 0 0 337106 452764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521988 0 449288 502753 992894 710862 0 463413 0 483689 0 536111 1651943 0 0 1005241 0 1493933 0 543702 0 518454 1415651 576077 0 591987 0 1210378 688959 702879 0 0 192444 0 0 472985 750141 542479 -(Gln->pyro-Glu)QTDLVEAMAK MGYG000002477_02889;MGYG000002534_02792;MGYG000002323_02376;MGYG000000093_03212;MGYG000002494_03237;MGYG000003372_04352;MGYG000002506_00505;MGYG000002515_01682;MGYG000002366_02168 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,400VK@613|Serratia 0.8888888888888888 1236|Gammaproteobacteria 1.0 M 1.0 Belongs to the KdsA family 1.0 kdsA 1.0 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046400,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 0.8888888888888888 2.5.1.55 1.0 ko:K01627 1.0 ko00540,ko01100,map00540,map01100 1.0 M00063 1.0 R03254 1.0 RC00435 1.0 ko00000,ko00001,ko00002,ko01000,ko01005 1.0 - 1.0 - 1.0 - 1.0 DAHP_synth_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-deoxy-8-phosphooctulonate synthase. phospho-2-keto-3-deoxyoctonate aldolase. Formerly EC 4.1.2.16. D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-alpha-D- manno-2-octulosonate-8-phosphate + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Lipopolysaccharide biosynthesis 1.0 none 1.0 0 115588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247887 321223 0 0 504149 0 0 0 354437 0 0 0 261410 0 0 418673 0 385129 0 0 526369 0 480042 0 0 0 0 694166 0 0 0 329350 0 0 0 0 366919 0 0 0 0 0 0 0 0 0 188120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260020 0 169714 0 0 331636 0 332666 0 0 0 0 95938 0 0 0 181059 0 0 0 0 99401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTENC(Carbamidomethyl)NSNSSISHEAVR MGYG000001346_01069 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1138817 420515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391714 1170427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1360175 707409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413950 664843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2663806 472667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTEQTTEAAVVEEGGGLHK MGYG000004797_01477 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488386 0 0 0 0 300976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1671478 0 0 0 0 2644938 0 0 0 0 1656184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 910212 0 0 0 0 687983 0 0 0 0 900240 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTESHAVK MGYG000002506_03516;MGYG000002494_01479;MGYG000002502_03943;MGYG000002500_04623;MGYG000002515_03540 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2820@1|root,COG2820@2|Bacteria,1P0EC@1224|Proteobacteria,1RN3N@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 udp 1.0 GO:0003674,GO:0003824,GO:0004850,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006218,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016043,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0022607,GO:0030955,GO:0031420,GO:0033554,GO:0034214,GO:0034641,GO:0034655,GO:0034656,GO:0042454,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046108,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0050896,GO:0051259,GO:0051716,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 1.0 2.4.2.3 1.0 ko:K00757 1.0 ko00240,ko00983,ko01100,map00240,map00983,map01100 1.0 - 1.0 R01876,R02484,R08229 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_2630,iB21_1397.B21_03667,iECABU_c1320.ECABU_c43290,iECBD_1354.ECBD_4198,iECB_1328.ECB_03718,iECD_1391.ECD_03718,iECNA114_1301.ECNA114_4136,iECOK1_1307.ECOK1_4296,iECP_1309.ECP_4040,iECS88_1305.ECS88_4275,iECSF_1327.ECSF_3683,iEcSMS35_1347.EcSMS35_4208,iLF82_1304.LF82_2357,iNRG857_1313.NRG857_19105,iUMN146_1321.UM146_19385,iUMNK88_1353.UMNK88_4655 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 uridine phosphorylase. UrdPase. The enzyme participates the the pathways of pyrimidine ribonucleosides degradation and salvage.-!-The mammalian enzyme also accepts 2'-deoxyuridine.-!-Formerly EC 2.4.2.23. phosphate + uridine = alpha-D-ribose 1-phosphate + uracil. 1.0 1.0 1.0 1.0 Metabolic pathways;Drug metabolism - other enzymes;Pyrimidine metabolism 1.0 none 1.0 182491 225463 0 307727 0 178553 203146 341486 279866 455102 0 264241 0 224853 458896 57809 0 0 255908 0 0 455540 0 0 424883 207982 198629 0 388480 245218 0 170795 0 440888 160014 183386 276219 259581 899625 704816 582841 1107909 150112 1408665 1168494 994413 663255 1441901 0 944016 0 1026116 646125 0 1274091 0 1085003 0 0 1078632 0 1024843 1052217 937639 920224 0 1009691 940946 0 792889 113704 821764 661289 647089 424121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1322958 1265780 1371289 1747474 968440 1059831 1813078 1319490 1132758 1243170 0 1423796 0 1153014 510219 683347 1396731 0 944222 0 0 1123000 0 1046277 1273934 1530028 1459213 0 987465 1592384 0 1103800 962660 1404127 1275185 542070 934285 859986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89434 0 0 0 0 0 186971 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTETTLVVN(Deamidated)QSANKPYIR MGYG000000074_00675 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1409@1|root,COG1409@2|Bacteria,4PNR4@976|Bacteroidetes,2FZJW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Putative binding domain, N-terminal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BACON 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTETTLVVNQSANKPYIR MGYG000000074_00675 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1409@1|root,COG1409@2|Bacteria,4PNR4@976|Bacteroidetes,2FZJW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Putative binding domain, N-terminal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BACON 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 124003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 646927 0 0 0 387867 0 0 0 0 0 658966 333626 1004926 0 948423 1479265 1000113 1216793 1291805 814152 1201135 1285649 0 0 1109965 0 1111616 798626 1180402 0 1778100 1640540 0 878411 0 886588 1075895 1149158 1018395 0 1188585 1879418 824858 773859 821676 0 1024012 1171975 1346122 1420459 -(Gln->pyro-Glu)QTFAEKPAEFDPR MGYG000000243_02506 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 3292926 4140964 7654486 3819904 6058801 4177543 4086046 3400504 3292070 2875542 3381627 3331996 7150531 3868021 3622899 6827301 3649071 5211362 2845189 2895106 3385625 3261830 5037379 4646125 3059752 3445927 3954859 5754355 3403383 4150509 5362080 4125456 7818448 3205362 4299819 4128568 3049339 7388035 2827709 2710249 3270030 3075631 4607174 2924935 2583040 3325924 2913587 2830304 3533799 2638865 7143541 2693499 2654538 5904323 2375026 3441163 2785684 2673509 2301876 3058390 4536729 2161453 2729509 2753044 3328846 3938523 2564221 3378157 2767025 3337795 2997120 2381245 3293121 3344310 2387715 2585936 1644867 2276128 3240539 1685071 4168983 2748024 2350517 1340090 3095320 1431577 1998014 2257044 3548667 2538629 1686268 3169907 1932304 5397472 1531589 1762323 1658969 1849112 4647636 3073194 1447251 2008794 1623850 5042620 2833796 1496685 2527628 1616156 1790731 965340 1900131 2882671 1899880 2414871 426906 627743 471254 537414 356555 630145 633461 581288 649567 774121 524767 768607 748825 366891 642579 621491 449921 0 406050 521926 632015 550700 0 474973 625110 354973 585653 210796 534281 479562 617148 583158 446675 413579 713446 629196 610898 682822 1911703 1637919 2189760 3097539 3711194 2492701 2984287 2785946 2853191 1153033 1921221 2741315 4785560 1886296 2250791 3114721 2226234 5530598 2568300 3012300 1742789 2405374 5622727 2179456 2912931 2578678 2258011 5508165 2728212 2726653 2623006 2200489 1899897 3183201 3331998 2526733 3221059 2727425 -(Gln->pyro-Glu)QTFAEKPAEFDPRK MGYG000000243_02506 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTFDKISAPEK MGYG000002528_00223 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,267YK@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01989 1.0 - 1.0 M00247 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 - 1.0 - 1.0 - 1.0 ABC_sub_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 598937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427550 0 251233 0 0 0 0 745657 0 0 435760 0 0 0 0 0 0 0 1100999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 473065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1181730 0 0 0 455491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1033370 0 388353 0 0 0 0 1171296 0 0 1188313 0 0 0 0 0 0 0 919131 0 0 0 726286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 904792 0 0 1013154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTFKELQDIC(Carbamidomethyl)KK MGYG000002528_02666;MGYG000001615_04302 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 0.5 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 0.5 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2067862 0 0 0 478158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 879525 0 460282 0 0 0 0 0 0 0 1501830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTFKELQDIVKK MGYG000000404_01796 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA11774|s__UBA11774 sp003507655|m__MGYG000000404 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,27IK9@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTGASDGSR MGYG000004797_02947;MGYG000000243_00135;MGYG000002478_02940 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 492608 0 0 0 0 0 0 0 0 0 636476 0 388832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809662 0 767585 0 0 0 0 956701 0 0 0 0 0 0 0 0 0 0 0 0 851653 0 372014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155046 0 0 0 0 0 0 0 223778 0 0 0 0 0 0 0 0 0 423253 0 130403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227801 0 155101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87832 0 0 0 0 0 0 0 0 0 188835 0 73748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107376 0 0 0 0 0 0 61509 -(Gln->pyro-Glu)QTGFAMLATSSVQEVMDLAGVAHLVSLK MGYG000001546_00078 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes provencensis|m__MGYG000001546 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,22U5S@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9935157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1591460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTGHMAAQVLK MGYG000000179_03811 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,267YK@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01989 1.0 - 1.0 M00247 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 - 1.0 - 1.0 - 1.0 ABC_sub_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1696102 0 0 0 0 0 0 0 0 0 371238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1711140 0 0 0 0 0 0 0 0 0 1625467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5762364 0 0 0 0 0 0 0 0 0 4215669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2044382 0 0 0 0 0 0 0 0 0 1216804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146864 0 0 0 0 0 0 0 0 0 1250501 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTGRPHGFLR MGYG000002323_00399;MGYG000002506_02948 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,3ZMD1@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site 1.0 rpsN 1.0 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02954 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S14 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 468418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 484626 0 468545 0 0 0 0 0 0 0 0 0 399648 0 138156 0 0 0 0 0 0 0 334880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366899 0 314546 0 0 0 0 0 0 0 0 0 223485 0 223465 0 0 0 0 0 0 0 988391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 646164 0 675099 0 0 0 0 0 0 0 0 0 569572 0 457753 0 0 0 0 0 0 0 374013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389375 0 317753 0 0 0 0 0 0 0 0 0 902002 0 432145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTGRPHGYVGK MGYG000002494_02456;MGYG000002535_04674;MGYG000002477_00174;MGYG000002534_00405 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,3ZMD1@590|Salmonella 0.5 1236|Gammaproteobacteria 1.0 J 1.0 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site 1.0 rpsN 1.0 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02954 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S14 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1864019 1534651 0 0 3249972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3111517 0 2289495 0 0 0 0 2093254 0 0 0 1989265 0 0 0 0 1365332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTGTVFNDHFSQAK MGYG000000242_00891 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,21Z0Q@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 K 1.0 PFAM regulatory protein GntR HTH 1.0 - 1.0 - 1.0 - 1.0 ko:K00375 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2,GntR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1673641 0 0 0 0 1581094 0 0 0 0 1708977 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTGTVFNDHFSQAR MGYG000000198_03565 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,21YYA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein-like domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 896305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTGTVFNNHFAQAQAASDIAVK MGYG000000233_02993 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,21YYA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein-like domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2129513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTHTVSGTVIDKDANEPLIGANVLIK MGYG000002478_01405;MGYG000004797_04333 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKS4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 402377 0 409025 0 0 0 0 0 0 0 294173 0 0 0 0 0 0 0 0 341576 0 0 0 0 0 200511 0 0 0 0 0 0 372009 0 0 0 252023 304907 585003 0 599691 0 0 0 0 0 0 0 776226 0 0 0 0 0 0 0 0 663763 0 0 0 0 0 662530 0 0 0 0 0 0 499785 0 0 0 638675 568864 512942 0 629891 0 0 0 0 0 0 0 258115 0 0 0 0 0 0 0 0 570686 0 0 0 0 0 573098 0 0 0 0 0 0 563343 0 0 0 532015 560589 231841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268737 0 410097 0 0 0 0 0 0 0 286652 0 0 0 0 0 0 0 0 317764 0 0 0 0 0 233166 0 0 0 0 0 0 303601 0 0 0 267424 416421 -(Gln->pyro-Glu)QTIDFHYGK MGYG000000013_03819;MGYG000002438_03404;MGYG000000196_02028;MGYG000001461_02234 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,2FNA0@200643|Bacteroidia,4AM34@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 C 1.0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems 1.0 sodB 1.0 - 1.0 1.15.1.1 1.0 ko:K04564 1.0 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Sod_Fe_C,Sod_Fe_N 0.75 - 1.0 - 1.0 - 1.0 - 1.0 superoxide dismutase. - - 2 H(+) + 2 superoxide = H2O2 + O2. 1.0 1.0 1.0 1.0 FoxO signaling pathway;MAPK signaling pathway - fly;Longevity regulating pathway - multiple species;Huntington disease;Peroxisome;Longevity regulating pathway;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4335637 0 0 0 0 0 0 0 0 5487997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4916350 0 0 0 0 0 0 0 0 4483318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6176147 0 0 0 0 0 0 0 0 8254033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6375286 0 0 0 0 0 0 0 0 4296934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5142237 0 0 0 0 0 0 0 0 6468000 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTIIQGQGEHHLNILR MGYG000000074_00169 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,22UNU@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Elongation factor G, domain IV 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 378765 0 0 0 0 0 0 0 0 0 0 0 0 865794 0 0 0 807724 0 0 0 0 0 0 0 0 0 875532 0 0 0 0 0 0 758016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 896254 0 0 0 977757 0 0 0 0 0 0 0 0 0 466773 0 0 0 0 0 0 365371 0 0 0 251355 0 0 0 0 0 0 0 0 0 0 0 0 428277 0 0 0 681226 0 0 0 0 0 0 0 0 0 501234 0 0 0 0 0 0 633381 0 0 0 226030 0 0 0 0 0 0 0 0 0 0 0 0 396810 0 0 0 506403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375394 0 0 0 971204 0 0 0 0 0 0 0 0 0 0 0 0 1125086 0 0 0 1825906 0 0 0 0 0 0 0 0 0 1624134 0 0 0 0 0 0 1069578 0 0 -(Gln->pyro-Glu)QTIVGINK MGYG000000354_01445 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-485|s__CAG-485 sp001701295|m__MGYG000000354 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,22WFX@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1469753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTIVHGQGEFHLR MGYG000001346_00804;MGYG000001780_04716;MGYG000000196_03773;MGYG000000243_00833;MGYG000001661_00370;MGYG000001313_03098;MGYG000001337_00442;MGYG000003363_00202;MGYG000002455_01659;MGYG000004797_02873;MGYG000004876_01617;MGYG000002171_00598;MGYG000000236_01356;MGYG000004748_03453;MGYG000002478_00020;MGYG000003922_00128 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,4AMQX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Psort location Cytoplasmic, score 9.26 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 1484940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1195706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1081710 0 0 0 0 0 0 0 0 0 0 0 0 0 1280726 0 0 0 0 1207850 0 0 0 0 884656 0 0 0 0 0 0 0 0 0 0 639319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 412606 0 0 0 0 0 0 313591 0 0 0 0 0 0 0 0 0 0 0 0 0 1145532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1085281 0 0 0 0 1502468 0 0 888539 0 0 0 1075478 0 0 0 -(Gln->pyro-Glu)QTIVQGQGEHHLNILK MGYG000000170_00137 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900240235|m__MGYG000000170 1.0 COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,22UNU@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Elongation factor G, domain IV 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTIVSGQGEFHLR MGYG000002438_00770;MGYG000001489_00758;MGYG000003521_01095 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,22VW0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 elongation factor G 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521777 0 399090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1063115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1680369 0 1177011 0 0 0 0 0 0 -(Gln->pyro-Glu)QTLDLGN(Deamidated)GSALTTNQK MGYG000003279_01169;MGYG000000003_00249 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG3047@1|root,COG3047@2|Bacteria,4NP9X@976|Bacteroidetes,2FMHB@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 COG NOG27406 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OMP_b-brl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 769669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTLDLGNGSALTTNQK MGYG000003279_01169;MGYG000000003_00249 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG3047@1|root,COG3047@2|Bacteria,4NP9X@976|Bacteroidetes,2FMHB@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 COG NOG27406 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OMP_b-brl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 297779 0 0 0 0 0 0 0 0 0 0 0 0 727989 549364 0 0 0 0 0 853434 0 0 0 0 832110 0 0 0 0 0 0 0 0 0 793018 328068 0 304548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343818 0 0 0 0 590789 0 0 0 0 0 0 0 0 0 303294 0 0 634572 0 0 0 0 0 0 0 0 0 0 0 0 351943 634575 0 0 0 0 0 494605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524582 0 279907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 195968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306739 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTLLFGGLESIQHNANRK MGYG000000243_01002;MGYG000002478_03878 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,2FNBF@200643|Bacteroidia,4AM0P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Psort location Cytoplasmic, score 1.0 pheT 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 1.0 6.1.1.20 1.0 ko:K01890 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 B3_4,B5,FDX-ACB,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 502505 0 356136 0 0 0 0 0 0 0 367892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 574176 0 0 0 0 424799 0 0 209765 0 228757 0 0 0 0 0 0 0 224167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70708 0 0 0 0 147735 0 0 0 0 124874 0 0 0 0 0 0 0 143628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1245659 0 0 524066 0 136997 0 0 0 0 0 0 0 336882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390495 0 0 0 0 432601 0 0 0 0 0 0 0 0 0 0 0 0 9603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7046322 0 0 0 0 0 -(Gln->pyro-Glu)QTLQNIIDR MGYG000002438_02191 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia,22WV0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Trigger factor 1.0 tig 1.0 - 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 106144 0 0 0 0 0 0 0 0 237113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417699 0 0 0 0 0 0 0 0 406079 0 0 0 0 0 0 0 0 127269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396094 0 0 0 0 0 0 0 0 196981 0 0 0 0 0 0 0 0 216366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338404 0 0 0 0 0 0 0 0 474845 0 0 0 0 0 0 0 0 493106 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTLVHGQGEFHLR MGYG000001345_03238;MGYG000001780_04716;MGYG000000196_03773;MGYG000001313_03098;MGYG000001337_00442;MGYG000003812_01202;MGYG000002171_00598;MGYG000000098_00698;MGYG000002478_00020;MGYG000002051_02357;MGYG000003681_00194;MGYG000001346_00804;MGYG000004823_02933;MGYG000000243_00833;MGYG000001661_00370;MGYG000001378_04098;MGYG000001370_00201;MGYG000003363_00202;MGYG000002455_01659;MGYG000004876_01617;MGYG000004797_02873;MGYG000000054_02613;MGYG000000236_01356;MGYG000004748_03453;MGYG000000013_01898;MGYG000003922_00128 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,4AMQX@815|Bacteroidaceae 0.9230769230769231 976|Bacteroidetes 1.0 J 1.0 Psort location Cytoplasmic, score 9.26 0.9230769230769231 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1163229 1426802 1509211 490066 2164639 0 1226509 1323706 1097602 933316 892978 1207183 1504529 1390439 1123440 1707851 1837102 757799 1035787 930335 1124109 1252259 1126003 1450567 1018726 1189171 1451497 0 1342417 1435598 2453200 1618973 1657769 0 1695965 1091825 1204467 1576458 880989 495137 1072650 838055 906183 752596 635450 1091870 1083179 1191881 1499896 1146144 693043 823307 1196986 1252469 1040394 500089 814325 822694 938817 786934 242408 661418 1018922 923523 1037823 380081 727635 1162355 508715 858251 741860 830767 1157369 781369 967275 1009754 860424 1101255 938536 1151606 1507350 1355141 929502 973501 0 1169925 1235206 1353809 984441 1175323 1104023 1085394 1110780 1090298 1256972 993970 905885 1004175 0 1384871 1103691 1264607 1124087 0 936702 958633 1127215 1026372 0 817774 1334934 1145771 1035817 1024438 459045 561976 701758 579526 503012 376925 565557 593718 456166 574460 368287 792872 512307 645178 537868 310642 407290 772261 675179 582894 676664 413738 616761 153644 522766 644158 576892 339374 500375 660796 304518 592643 442328 689361 769006 631791 714176 515471 904320 761798 1102672 938512 1661760 1247325 0 1251301 1245096 622604 906814 888875 1001583 633032 914061 1429015 877745 1741040 911417 958387 636467 1180666 0 1434139 987945 983635 561955 0 1013779 1075713 0 1050791 738311 1198446 0 684013 1064924 963272 -(Gln->pyro-Glu)QTNAKPVTGR MGYG000000271_00190 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 Signal transducing histidine kinase homodimeric 1.0 cheA 1.0 - 1.0 2.7.13.3 1.0 ko:K03407 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW,H-kinase_dim,HATPase_c,Hpt,P2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 histidine kinase. protein kinase (histidine). This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine).-!-A number of histones can act as acceptor. ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTSTNYEEASNPISTNPSLWVK MGYG000000243_00778 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3934@1|root,COG3934@2|Bacteria,4NF13@976|Bacteroidetes,2FNPI@200643|Bacteroidia,4ANXT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Domain of unknown function (DUF4091) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4091 1.0 3.2.1.53|3.2.1.- 1.0 GH123 1.0 GH123 1.0 GH123 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 618222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850966 0 717598 0 0 0 0 609371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTTFGELDK MGYG000001157_01000;MGYG000004732_01389;MGYG000003937_01090;MGYG000002619_02238;MGYG000001300_00294;MGYG000004866_01549;MGYG000000022_01323;MGYG000001255_01113;MGYG000002272_01496;MGYG000003166_01335;MGYG000002040_01716 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 0.9090909090909091 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 0.9090909090909091 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 229842 519185 568887 0 0 266268 238398 0 420125 0 0 0 777961 402278 600115 0 162604 0 930439 872327 0 770452 0 413416 129391 382221 622235 0 0 0 0 0 0 680567 371780 0 491057 0 1033768 1361120 1210224 0 757798 1523758 1733741 0 1449779 0 0 1596331 887171 1439679 944037 0 953344 0 1976156 1505591 0 958012 0 1383702 1554268 1250700 1101546 0 0 1258777 1422452 1102722 1026511 940290 428788 918296 1034271 1332191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239985 0 0 0 0 0 0 0 214857 0 0 0 0 479753 509928 814729 0 900357 701865 821114 0 790672 0 0 706519 856557 787587 319166 0 612994 0 1021523 536760 0 428240 0 266082 366891 601224 398833 0 0 666353 805895 574244 867363 619702 0 647447 444638 966689 0 0 97211 0 0 192065 0 0 117562 0 0 189537 299576 0 0 0 113450 0 0 181646 0 309876 0 0 101281 84706 108171 0 0 312290 0 151117 0 0 317685 0 0 126420 -(Gln->pyro-Glu)QTTFGELDKIC(Carbamidomethyl)KPE MGYG000003937_01090;MGYG000001300_00294;MGYG000003166_01335 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 854232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 750408 0 0 0 0 1384735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTTFNDMIK MGYG000000235_01320;MGYG000002506_04114;MGYG000002534_04109;MGYG000002515_04341 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0813@1|root,COG0813@2|Bacteria,1MUW6@1224|Proteobacteria,1RMMA@1236|Gammaproteobacteria,3WWYQ@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Phosphorylase superfamily 1.0 deoD 1.0 GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 1.0 2.4.2.1 1.0 ko:K03784 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_1997,iB21_1397.B21_04226,iE2348C_1286.E2348C_4682,iEC042_1314.EC042_4881,iECABU_c1320.ECABU_c50190,iECBD_1354.ECBD_3636,iECB_1328.ECB_04260,iECD_1391.ECD_04260,iECED1_1282.ECED1_5255,iECIAI39_1322.ECIAI39_4916,iECNA114_1301.ECNA114_4626,iECO26_1355.ECO26_5590,iECOK1_1307.ECOK1_4950,iECP_1309.ECP_4768,iEcolC_1368.EcolC_3672,iLF82_1304.LF82_0467,iNRG857_1313.NRG857_22170,iPC815.YPO0440,iSFV_1184.SFV_4418,iSF_1195.SF4416,iSFxv_1172.SFxv_4809,iS_1188.S4687,iUMN146_1321.UM146_22680,iUMNK88_1353.UMNK88_5303,iUTI89_1310.UTI89_C5155,ic_1306.c5468 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Metabolic pathways;Nicotinate and nicotinamide metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTTTVTSIETFHK MGYG000002395_00576;MGYG000003452_00658 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 717324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1286085 0 1313874 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTVAKPVTNR MGYG000002517_01392 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 Signal transducing histidine kinase homodimeric 1.0 cheA 1.0 - 1.0 2.7.13.3 1.0 ko:K03407 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW,H-kinase_dim,HATPase_c,Hpt,P2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 histidine kinase. protein kinase (histidine). This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine).-!-A number of histones can act as acceptor. ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 171827 0 0 0 0 0 356392 0 0 103690 0 0 546035 0 0 0 0 0 0 0 0 0 0 0 159513 0 0 406254 0 0 187264 375426 0 0 0 339560 0 0 226247 0 0 0 0 0 379246 0 0 78482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 97337 0 0 0 0 0 217053 242763 0 0 0 139580 0 0 0 0 0 0 0 0 405731 0 0 246823 0 0 630013 0 0 0 0 0 0 0 0 0 0 0 531844 0 0 498771 0 0 0 367820 0 0 0 0 0 0 0 0 0 0 0 0 2519819 0 0 1247353 0 0 2900285 0 0 0 0 0 0 0 0 0 0 0 2179407 0 0 1822938 0 0 0 1464807 0 0 0 0 0 0 1492879 0 0 0 0 0 1755830 0 0 1611564 0 0 1889187 0 0 0 0 0 0 0 0 0 0 0 1153163 0 0 963472 0 0 1173381 1555839 0 0 0 1269799 -(Gln->pyro-Glu)QTVDPAVKAPEVTDK MGYG000002619_00997;MGYG000002545_01731;MGYG000002610_01679;MGYG000003291_00558;MGYG000001300_01680;MGYG000002040_01831;MGYG000003166_01503;MGYG000002272_02058;MGYG000001255_01666 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4,Fer4_10,Fer4_4,Fer4_7,Fer4_8,Fer4_9,MTHFR_C,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390002 0 0 0 0 0 0 283546 0 0 0 0 0 0 0 0 0 0 274386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTVEEVLSSIGPVVDAHPEYEKVALLER MGYG000000233_02492 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,222GB@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTVNEIGYNDAK MGYG000002517_00444 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25V3W@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme 1.0 metK 1.0 - 1.0 2.5.1.6 1.0 ko:K00789 1.0 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 1.0 M00034,M00035,M00368,M00609 1.0 R00177,R04771 1.0 RC00021,RC01211 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N,YgbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methionine adenosyltransferase. S-adenosylmethionine synthetase. Formerly EC 2.4.2.13. ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L- methionine. 1.0 1.0 1.0 1.0 Biosynthesis of amino acids;Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633083 0 0 0 0 0 0 0 415352 0 0 0 0 0 0 0 0 223969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTVYTASPESQQIHVWSLNHDGSLK MGYG000002494_00779 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2706@1|root,COG2706@2|Bacteria,1MWGS@1224|Proteobacteria,1RNX2@1236|Gammaproteobacteria,3XMN9@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate 1.0 pgl 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 1.0 3.1.1.31 1.0 ko:K07404 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 1.0 M00004,M00006,M00008 1.0 R02035 1.0 RC00537 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iSSON_1240.SSON_0741 1.0 Lactonase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphogluconolactonase. - - 6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 555287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTYAFAAGTKK MGYG000002528_02671 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Acetyl-CoA hydrolase transferase 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 535160 0 0 0 222635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1486551 0 0 0 264875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 913755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QTYAFGAGTKK MGYG000002517_02708;MGYG000000164_00689 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Acetyl-CoA hydrolase transferase 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 820860 650922 0 0 0 0 0 0 0 266331 547851 1698559 0 1188659 1304379 0 0 0 0 0 0 0 0 660386 0 0 0 0 1245132 0 0 352767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230249 0 279135 0 0 371883 0 0 0 0 0 0 0 0 0 0 0 0 0 662831 0 0 372489 0 0 0 0 527694 0 0 738375 0 0 0 0 0 0 0 762842 1228761 757525 0 2338573 706906 0 0 0 0 0 0 0 0 2933256 0 0 0 0 2044689 0 0 527155 0 0 0 0 492265 0 1650382 0 0 0 0 0 0 0 0 2064314 2956527 664610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1914681 0 0 0 0 0 -(Gln->pyro-Glu)QVAAGSGC(Carbamidomethyl)YTHVVENTAR MGYG000000262_02783;MGYG000000262_02732;MGYG000000077_00328 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,25UUE@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Carbon-monoxide dehydrogenase, catalytic subunit 1.0 cooS 1.0 - 1.0 1.2.7.4 1.0 ko:K00198 1.0 ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200 1.0 M00377 1.0 R07157,R08034 1.0 RC00250,RC02800 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Prismane 1.0 - 1.0 - 1.0 - 1.0 - 1.0 anaerobic carbon-monoxide dehydrogenase. Ni-CODH. This prokaryotic enzyme catalyzes the reversible reduction of CO2 to CO.-!-The electrons are transferred to redox proteins such as ferredoxin.-!-In purple sulfur bacteria and methanogenic archaea it catalyzes the oxidation of CO to CO2, which is incorporated by the Calvin-Benson- Basham cycle or released, respectively.-!-In acetogenic and sulfate-reducing microbes it catalyzes the reduction of CO2 to CO, which is incorporated into acetyl CoA by EC 2.3.1.169, with which the enzyme forms a tight complex in those organisms.-!-In purple sulfur bacteria the enzyme forms complexes with the Ni-Fe-S protein EC 1.12.7.2 which catalyze the overall reaction: CO + H2O = CO2 + H2. cf. EC 1.2.5.3.-!-Formerly EC 1.2.99.2. CO + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Nitrotoluene degradation;Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 649218 0 0 0 527841 0 0 0 0 0 0 0 0 0 510435 0 0 0 0 0 545067 0 0 0 0 0 0 0 0 0 0 0 528923 609445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220856 0 0 0 0 0 0 0 0 0 0 0 0 0 623511 0 0 0 0 0 487429 0 503647 0 0 0 0 0 0 668681 0 0 309198 147979 0 0 0 -(Gln->pyro-Glu)QVAEGALNETHSILQR MGYG000000187_02828;MGYG000000389_01367;MGYG000000076_03207;MGYG000001186_01647;MGYG000004317_00523 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.8 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 7761711 3737731 8016070 14693557 8584396 6344447 5167425 10675297 0 0 0 8683824 9019580 0 9002966 8184428 0 0 15431893 6777325 8204203 5164995 0 6891220 8403339 10085061 12498496 0 1780821 13598834 4821542 3841687 5297295 8982098 8439476 7983035 9381683 5111340 569027 310183 285161 435076 318820 588744 0 411517 464489 0 0 292134 601254 1078503 378239 610620 405437 0 495364 0 479425 208605 0 0 956572 426400 299108 0 463930 1349371 0 0 365591 566343 392343 376554 222118 268439 5777634 2064509 963690 5130466 3570042 2511638 4726172 5773421 7317665 0 0 8352811 5673363 6002783 6669721 3863906 3881943 0 5717203 4281466 3720145 910401 0 1229322 8623629 10908519 6468833 0 1303037 5602489 2308597 1153355 1505340 4651872 8201250 7253646 10414819 1154902 0 0 433438 0 680384 263518 1169236 320793 832197 0 0 284487 306405 0 265642 215241 254803 0 0 348167 401200 206476 0 0 346157 252612 0 0 237931 0 281933 236876 252129 322507 316621 0 209568 211446 580209 0 2204757 558959 290677 1626263 1038475 78406 518703 0 0 0 239080 0 259782 71566 390808 0 330365 286812 0 160637 0 253168 298683 344821 0 0 210210 409237 0 0 899241 335026 194092 489880 290876 0 -(Gln->pyro-Glu)QVAEGALSETHSILQR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 1234408 1025448 1145438 1310671 1712010 1174216 1488883 1678960 2312541 2173309 954612 1414835 1382776 2240344 1218508 1599271 1887047 0 1438302 802149 1139117 986954 0 1214725 1349891 1350572 1117389 0 1312802 1595376 1645272 1318416 956420 1569829 1521121 1401671 1930214 1071807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261824 0 0 0 0 0 0 0 0 0 0 301257 0 0 0 0 0 20367219 5647117 6523086 28385475 16392607 8393000 15487654 47690690 37586166 13744129 11080328 21793850 10573421 46633871 51538328 13918975 20499157 0 29263112 21027388 21302577 2893022 0 2690542 51294205 48637216 33913144 0 6240426 28102582 6207312 8846478 5149577 39812043 37863310 30589603 45122988 6209053 15741562 8141936 14112612 5921404 15378940 20539931 6431544 9834132 13880725 24608500 16993519 11916432 25355895 14666562 20780251 11543627 16376325 0 18658255 15968572 12345665 12803547 0 23611262 20768116 18941575 23847768 0 5703304 21340849 15310574 8791279 17929295 22414343 22280906 12262389 30971009 23071790 -(Gln->pyro-Glu)QVAILAVAGAEK MGYG000002494_02408;MGYG000002506_03406;MGYG000000235_03967;MGYG000002534_04893;MGYG000002477_00658;MGYG000002323_04219;MGYG000002535_04275 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,3X0ZA@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) 1.0 atpF 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902600 1.0 - 1.0 ko:K02109 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664 1.0 ATP-synt_B 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381763 380362 0 389821 662058 0 0 0 437959 0 0 0 0 0 0 591108 0 470964 0 0 779308 0 678120 0 0 0 0 473477 0 0 0 327002 0 0 0 0 251248 0 0 0 0 0 189941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 149984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64978 0 0 0 0 105402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVAIVKR MGYG000004797_02827;MGYG000001056_01201;MGYG000004899_03971;MGYG000003697_01312;MGYG000002737_00135;MGYG000000196_04055;MGYG000001787_00508;MGYG000000243_00691;MGYG000002293_02133;MGYG000002478_00464;MGYG000000215_00958;MGYG000001313_02959;MGYG000000098_03787 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,2FMKX@200643|Bacteroidia,4AMQC@815|Bacteroidaceae 0.6153846153846154 976|Bacteroidetes 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO,NanE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVC(Carbamidomethyl)ETLEK MGYG000000142_02834;MGYG000002279_01986;MGYG000000184_00575;MGYG000004785_01840;MGYG000000031_02405;MGYG000001338_02151;MGYG000002203_00507 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.7142857142857143 186801|Clostridia 0.8571428571428571 G 0.8571428571428571 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 0.7142857142857143 ppdK 0.8571428571428571 - 1.0 2.7.9.1 0.8571428571428571 ko:K01006 0.8571428571428571 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.8571428571428571 M00169,M00171,M00172,M00173 0.8571428571428571 R00206 0.8571428571428571 RC00002,RC00015 0.8571428571428571 ko00000,ko00001,ko00002,ko01000 0.8571428571428571 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.8571428571428571 - 1.0 - 1.0 - 1.0 GT1 0.8571428571428571 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 0.8571428571428571 none 1.0 0 239351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116924 0 0 0 0 0 0 0 495013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1119562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1345961 0 0 0 0 0 0 0 577410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 620935 0 0 0 0 0 0 0 1355896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1175111 0 0 0 0 0 0 -(Gln->pyro-Glu)QVC(Carbamidomethyl)ETLEKHYR MGYG000000142_02834;MGYG000002279_01986;MGYG000000031_02405;MGYG000001338_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.75 186801|Clostridia 1.0 G 1.0 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 0.75 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVC(Carbamidomethyl)QTLEDHYR MGYG000000077_02459 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum soehngenii|m__MGYG000000077 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25VEG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 638586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVDDKVLAALVK MGYG000002517_02936 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 2.2.1.2,5.3.1.9 1.0 ko:K01810,ko:K13810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00004,M00007,M00114 1.0 R01827,R02739,R02740,R03321 1.0 RC00376,RC00439,RC00563,RC00604 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. | glucose-6-phosphate isomerase. glycerone transferase. | phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 91459 115411 184292 0 0 0 107814 183158 0 180571 0 185938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89108 125607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109079 0 0 0 0 0 0 0 0 78419 0 0 0 0 0 85041 104100 0 0 0 0 0 0 0 0 81491 0 74832 0 916632 0 156575 0 0 293862 501966 1341817 1081567 632612 368859 503524 0 1208288 1507195 0 724627 0 1021491 0 0 0 0 0 1125506 1293356 0 0 0 0 216615 0 209475 846480 1134178 961035 1398633 129323 502536 0 951172 0 0 914061 689579 389047 605078 978612 555656 673692 0 755549 849475 0 855769 0 629156 0 0 445855 0 532897 687732 679702 0 0 0 0 471689 0 910216 481004 743910 776572 766851 642167 -(Gln->pyro-Glu)QVDNVLDGVAFELLGK MGYG000002517_00544 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 251146 0 0 0 0 0 0 778181 0 0 0 0 0 0 0 0 0 0 330859 0 0 0 354256 0 0 0 0 0 0 357668 0 453137 0 0 0 0 0 0 1047168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2805356 485507 0 0 0 0 0 0 0 0 0 0 0 0 244471 0 0 0 0 0 0 204381 0 0 0 0 0 0 1182055 0 0 0 0 0 0 0 0 0 2376782 0 0 0 0 210293 0 0 0 0 0 0 0 0 1980776 0 0 0 0 0 0 2384712 0 0 0 0 0 0 2755694 0 0 0 0 0 0 0 0 0 1929186 2186822 0 0 0 3233882 0 0 0 0 0 0 2126771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVEAEETTK MGYG000004712_00508;MGYG000000200_01193;MGYG000002312_00710;MGYG000004785_01922;MGYG000001338_00217;MGYG000002989_00657;MGYG000000356_00231;MGYG000003215_00942 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia 0.5 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 489437 233632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168595 563435 248288 0 0 0 0 310491 0 877265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 944349 511385 0 0 0 0 0 0 0 556146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 601354 0 0 0 0 0 0 0 553926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 818127 475670 387251 0 0 0 0 330055 0 743467 353011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608004 1092345 694262 0 0 0 0 325294 -(Gln->pyro-Glu)QVEEAGGKVELK MGYG000002720_01642;MGYG000004487_00623;MGYG000002143_01057;MGYG000002156_00936 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2N7E0@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1283835 1395268 0 0 0 1397602 0 780082 0 0 0 0 0 1748795 0 0 0 0 0 0 0 1582411 0 1635485 1087362 1220421 0 0 0 0 0 0 0 0 0 1355613 1405096 0 670566 157245 0 0 0 0 0 0 0 0 0 0 0 181279 0 0 0 0 0 0 0 351336 0 0 0 0 0 0 0 0 0 0 0 0 0 444957 540139 0 799836 0 0 0 0 0 0 0 0 0 0 0 0 612436 0 0 0 0 0 0 0 0 0 0 0 350062 0 0 0 0 0 0 0 0 0 0 350222 0 749947 948602 0 0 0 1025161 0 1243306 0 0 0 0 0 1091259 0 0 0 0 0 0 0 934644 0 1141785 1381202 1572596 0 0 0 0 0 0 0 0 0 1334752 1288261 0 0 0 0 0 0 0 0 145681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVEEEIIETGKR MGYG000001780_03543 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__|m__MGYG000001780 1.0 COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia,4AKD2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Endoribonuclease that initiates mRNA decay 1.0 rny 1.0 - 1.0 - 1.0 ko:K18682 1.0 ko03018,map03018 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03019 1.0 - 1.0 - 1.0 - 1.0 DUF3552,HD,KH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 660749 703682 0 736001 0 0 0 0 0 0 0 0 0 0 604416 0 0 0 0 0 0 0 0 600607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378812 300821 0 0 0 0 0 0 0 0 0 0 0 0 273911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316779 0 0 347403 0 0 0 0 0 0 0 0 0 0 274466 0 0 0 0 0 0 0 0 345570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534936 0 0 719601 0 0 0 0 0 0 0 0 0 0 596287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435986 0 0 181484 0 0 0 0 0 0 0 0 0 0 167735 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVEEVGGKVELK MGYG000002926_01367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2N7E0@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 322803 0 0 301713 0 0 339389 169369 402861 0 0 0 0 248795 307978 0 0 0 0 0 0 0 0 0 346829 243348 0 0 0 0 0 0 301747 398212 0 0 0 0 0 0 0 310097 0 0 246448 357269 0 316397 0 0 0 0 228055 0 0 0 0 0 0 0 0 0 0 323031 534204 0 0 0 0 0 0 229055 448486 0 400725 230452 1138625 0 901289 1061751 0 0 1012586 1262467 1161741 1034123 0 0 1176672 1007429 1181820 0 0 0 1206314 1034576 800607 0 0 0 975415 1255278 1199229 0 837950 0 0 0 851180 1064892 1269481 0 1169116 714935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVEFITEQYKR MGYG000002528_01102 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,267JY@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 437171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410989 0 315504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618053 0 0 0 410263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603296 0 307044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396774 0 221005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVFAEKPAEFDPR MGYG000002575_01735;MGYG000001306_00718;MGYG000000273_02673 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.6666666666666666 976|Bacteroidetes 1.0 G 0.6666666666666666 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.6666666666666666 fba 0.6666666666666666 - 1.0 4.1.2.13 0.6666666666666666 ko:K01624 0.6666666666666666 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6666666666666666 M00001,M00003,M00165,M00167,M00344,M00345 0.6666666666666666 R01068,R01070,R01829,R02568 0.6666666666666666 RC00438,RC00439,RC00603,RC00604 0.6666666666666666 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 680524 0 0 909401 0 0 0 0 0 2838084 0 0 0 0 4130826 0 0 0 0 4389663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVFGEDTDVKDEAAFR MGYG000003697_01308;MGYG000002960_01695;MGYG000002080_00708;MGYG000002834_01496 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 O 1.0 Trigger factor 1.0 tig 1.0 - 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1222268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802725 0 0 0 0 1153333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVFGVTFEQGR MGYG000002528_02568;MGYG000002992_01014;MGYG000002603_01825;MGYG000000171_02639;MGYG000000212_00042;MGYG000002279_00204;MGYG000000233_01645;MGYG000000142_02311;MGYG000000201_03105;MGYG000002960_01934;MGYG000000255_00249;MGYG000000205_01720;MGYG000003697_02648;MGYG000002293_00459;MGYG000000028_00883;MGYG000000216_01228;MGYG000002834_02512 domain d__Bacteria 1.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3XYNE@572511|Blautia 0.4117647058823529 186801|Clostridia 0.7058823529411765 F 1.0 AICARFT IMPCHase bienzyme 0.47058823529411764 purH 0.7058823529411765 - 1.0 2.1.2.3,3.5.4.10 1.0 ko:K00602 1.0 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 1.0 M00048 1.0 R01127,R04560 1.0 RC00026,RC00263,RC00456 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 AICARFT_IMPCHas 0.8235294117647058 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylaminoimidazolecarboxamide formyltransferase. | IMP cyclohydrolase. aminoimidazolecarboxamide ribonucleotide transformylase. | inosinicase. - (6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. | H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. 1.0 1.0 1.0 1.0 Antifolate resistance;Metabolic pathways;One carbon pool by folate;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVGLGHGNLGAR MGYG000001300_02120;MGYG000002274_00309;MGYG000000039_01269 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2108676 2261719 3090271 2463389 1161202 2271037 1477040 1495151 2170793 2026440 1592341 746537 2672406 2730697 2149273 2705203 2241991 3719966 3735892 2878168 1031627 2383122 2758514 1729451 2305377 1883504 2171051 3107657 0 1250994 2068062 1558652 3003500 3299348 1162193 2217014 1739529 2436628 6874881 3220570 5162792 5906133 2499768 3809686 7112639 2814229 7638691 1806060 2702308 4228003 3289190 6074847 5391569 3406278 6317385 4005252 6541033 6044580 2545335 2790478 4636992 3336988 7472929 5995613 6202257 4887387 0 3947215 4366958 2711884 4948801 6332890 2884345 5787166 6289782 5066047 1815293 1145070 811261 1666337 1353499 1316425 1604942 1614179 1718320 1388707 1615230 1163151 1644610 1748213 1865524 1447037 1126888 4140665 1538575 1511675 1636109 749502 4345087 1382031 1551066 1470843 1708147 5053185 0 1634711 1271573 1487599 892670 1966865 1009191 1621399 1400052 1239329 3346898 2800444 5656540 3713291 3852568 4476691 5362422 2040235 4001639 3141500 3912254 4277681 5369729 3682634 3486529 3794106 3399570 4664347 5448164 4051843 3314771 4627482 4997512 3955824 3889169 3762426 3136786 4447521 0 4682201 4292699 3391768 4665613 5357898 1444389 3387682 3317833 4788247 829251 563405 1150730 784778 967899 745736 516065 877215 729402 767463 431636 1022865 883985 805488 773835 711273 748003 3256835 632950 825924 1085186 731766 3742577 488825 825700 750764 654638 4176017 0 837980 651033 895347 1025309 787856 159979 865777 684733 1314573 -(Gln->pyro-Glu)QVGQTGVTVRPK MGYG000001415_00122;MGYG000000074_02401;MGYG000002867_00909 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 - 1.0 ko:K03522 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 232175 0 0 0 0 373633 0 0 295291 0 0 0 0 0 557272 0 375940 0 521854 229727 0 0 0 264314 0 500056 0 0 155467 543038 0 0 333929 0 0 337138 277821 0 204993 0 342519 0 0 200431 0 432873 430115 0 0 0 0 0 315770 0 0 0 448428 375449 0 0 0 0 0 211243 0 0 324641 403120 0 0 324199 0 0 295391 293123 396769 224440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332869 0 0 0 0 0 0 0 0 0 0 241243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265451 242573 0 0 0 0 0 347371 0 0 0 0 159030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740405 0 788963 0 0 861125 0 828146 922001 0 0 0 0 0 760618 0 840612 0 1433553 1450003 0 602692 0 795638 0 1479016 0 0 753087 1191593 0 0 344753 0 0 722801 966860 724811 -(Gln->pyro-Glu)QVGVPYIIVFLNK MGYG000003486_01055;MGYG000002492_00344;MGYG000002515_03208;MGYG000002515_03657;MGYG000004704_00398;MGYG000001635_01137;MGYG000002506_03686;MGYG000000412_01546;MGYG000002506_02966;MGYG000000045_02616;MGYG000001400_03001;MGYG000000121_02189 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,3ZITI@590|Salmonella 0.3333333333333333 186801|Clostridia 0.3333333333333333 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.6666666666666666 tuf 1.0 - 0.8333333333333334 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2479700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152140831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVGVPYIVVFLNK MGYG000002854_00111;MGYG000002106_00224;MGYG000003425_03741;MGYG000000245_03248;MGYG000004724_00878;MGYG000001567_01738;MGYG000002563_00522;MGYG000000404_00531;MGYG000001507_06245;MGYG000000291_00377;MGYG000002126_00299;MGYG000003411_00716;MGYG000000266_00259;MGYG000000919_01815;MGYG000002854_00124;MGYG000001299_01777;MGYG000001623_00993;MGYG000004221_01651;MGYG000002563_00509;MGYG000003266_00392;MGYG000000157_01091;MGYG000003073_01160;MGYG000002042_00774;MGYG000002517_00205;MGYG000001485_02164;MGYG000000223_03134 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CUFV@84998|Coriobacteriia 0.2692307692307692 186801|Clostridia 0.5384615384615384 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9230769230769231 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.9615384615384616 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 583291 0 0 0 0 1612212 261024 218859 254680 0 0 4064792 0 0 612126 2374890 0 0 0 0 2759797 0 0 751533 2692605 448912 135275 0 0 0 0 0 0 0 4500203 229219 1483943 238757 14040243 0 6810290 0 0 353916 6013683 23166481 0 452555 0 0 0 7375463 14234140 0 486028 0 0 0 0 0 0 0 31248932 0 7976119 0 0 0 0 0 20534142 0 31260598 12060434 13548685 26202013 960126 0 0 0 0 0 1429329 1639398 1146541 1449628 0 0 0 0 2667977 4390273 3306914 0 0 0 4534269 0 0 0 2260297 3222640 1179883 0 0 0 0 0 0 2196679 3251177 966028 2013597 0 5249339 0 914400 0 0 0 2244818 1420952 5018462 1529999 0 2937904 0 1615322 5773866 4438931 2190800 0 2252528 0 5256485 4880973 0 0 4488991 5025899 1581795 0 0 0 0 0 8957205 0 1798812 2860931 5834582 5115095 9093962 0 19736896 0 13323840 7466847 8221832 2634890 7487794 7886630 0 7717255 0 7974354 5714652 4764924 11162908 0 7078719 0 4552297 2872597 0 10679205 6566055 5986877 10427504 0 0 0 0 0 9767457 3627462 8989509 11189067 4000969 2392929 -(Gln->pyro-Glu)QVGVPYIVVFMNK MGYG000000080_02058;MGYG000000171_02844;MGYG000001673_01975;MGYG000000089_01901;MGYG000001688_04229;MGYG000002619_00483;MGYG000001654_02237;MGYG000004718_00646;MGYG000004735_00884;MGYG000000280_01200;MGYG000001714_01291;MGYG000001760_00949;MGYG000000198_01165;MGYG000000392_00966;MGYG000000133_02991;MGYG000003185_01074;MGYG000002202_00030;MGYG000003895_00135;MGYG000001619_01314;MGYG000000216_02406;MGYG000000034_01346;MGYG000004296_01668;MGYG000003549_00407;MGYG000001809_00576;MGYG000001652_01300;MGYG000000127_03982;MGYG000000258_00266;MGYG000001338_03373;MGYG000001300_00280;MGYG000001611_00087;MGYG000000255_02009;MGYG000002040_01212;MGYG000000164_01096;MGYG000002234_01026;MGYG000001606_01669;MGYG000000032_01232;MGYG000002105_00002;MGYG000002224_01123;MGYG000000036_01380;MGYG000000262_00030;MGYG000001615_01716;MGYG000000016_02519;MGYG000002279_01932;MGYG000001756_00183;MGYG000000201_03875;MGYG000003063_00662;MGYG000000271_03365;MGYG000000185_02848;MGYG000001315_01207;MGYG000001602_02247;MGYG000003273_00234;MGYG000000140_01590;MGYG000001065_02730;MGYG000000022_02283;MGYG000002528_01098;MGYG000004680_02443;MGYG000001436_02249;MGYG000003899_01642;MGYG000003891_00382;MGYG000000179_00920;MGYG000001749_02490;MGYG000001779_00600;MGYG000000177_01044;MGYG000002290_01325;MGYG000001531_00906;MGYG000001607_01045;MGYG000001141_02439;MGYG000003166_01350;MGYG000000251_00064;MGYG000000233_00807;MGYG000000142_00171;MGYG000002702_01978;MGYG000001528_00736;MGYG000004087_00551;MGYG000001439_02427;MGYG000000242_00282;MGYG000002417_01244;MGYG000000187_02029;MGYG000002641_00069;MGYG000000733_01034;MGYG000001698_04050;MGYG000000212_03313;MGYG000003074_01359;MGYG000003185_01053;MGYG000002837_02416;MGYG000000193_02083;MGYG000002272_01482;MGYG000002212_00196;MGYG000003236_02455;MGYG000001665_01696;MGYG000004630_01824;MGYG000001814_01592;MGYG000003504_00096;MGYG000001617_01406;MGYG000001732_00030;MGYG000000206_00901;MGYG000004733_01211 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.24742268041237114 186801|Clostridia 0.9484536082474226 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9587628865979382 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.9587628865979382 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 14071210 0 2996072 6107834 5660032 224315 0 18831506 14557337 6243690 6000937 20034447 0 199139 946707 0 0 9959904 1586893 12670446 21311066 6572949 6602246 7904464 8950914 325021 2260914 9453514 16178567 0 192228 20672450 14056265 9467006 23401947 384061 8091094 786017 320150 297912 624361 3061130 18964878 19213790 0 1080586 4276993 8612972 10020782 574098 0 252427 2281784 0 0 15186981 13476923 12044315 10338258 3730887 2528319 495100 661135 6326305 5482934 923388 4950944 0 8944254 7802516 13103786 3341646 10062492 3566617 6777350 15667192 8933136 7009569 1281426 278219 8235269 8176362 0 0 1822869 4205900 6891925 412158 0 12618022 4744501 0 0 8917281 12544509 9793898 5166534 145015 16514714 7971729 1688178 3613959 189788 15241988 16648892 0 3731413 19733440 12092318 0 16257971 1693165 1890540 4096717 187100 5415335 6279940 0 0 2432040 0 0 3260265 184050 8342334 197354 0 6603345 4434092 0 0 0 5800424 5957532 3583695 5027630 0 4379629 2715411 210585 0 0 2705946 0 4001877 7706516 4766633 5174653 2084368 97638 2105399 3391684 12246439 41568386 17618721 41155468 5069774 3913140 0 16358022 4910673 10160329 38331328 22902770 0 66077962 7950733 0 0 0 9334136 10971335 14934362 26506300 12964200 15831038 20504653 20458431 31422814 15076582 17770810 0 28431194 8805252 64173786 27599446 40454290 11246187 15029040 7010222 -(Gln->pyro-Glu)QVGVPYLVVFMNK MGYG000001412_04734;MGYG000001405_04470;MGYG000001469_02077 class d__Bacteria|p__Firmicutes|c__Bacilli 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,1ZCZK@1386|Bacillus 1.0 91061|Bacilli 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 iSB619.SA_RS02960 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 17318545 0 0 0 12903784 0 0 0 0 0 0 0 13157664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16791071 0 0 0 650695 0 0 0 0 0 681367 0 0 0 0 0 0 0 0 0 0 0 0 22686738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17913244 0 0 0 0 0 0 0 0 0 0 0 0 0 25113373 0 0 0 0 14570584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431674 0 3760472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVHC(Carbamidomethyl)VNLTESTIEANKR MGYG000002492_02662 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,25VFM@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 - 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 923268 0 0 0 0 544675 0 0 0 0 845087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577956 0 0 0 0 858730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVHTISIDPEVIKR MGYG000001306_02264 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 707492 0 0 0 0 0 0 0 0 0 723673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 61446 0 0 0 0 72715 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVHTLSIDPEVIKR MGYG000001783_01353;MGYG000001306_02264 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 580819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135668 0 0 0 0 138116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVHTLSIDPEVIQR MGYG000003693_03082 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 949436 0 0 0 0 1493115 0 0 0 0 1136959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520167 0 0 0 0 414362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVIDASHAEGK MGYG000002535_01117;MGYG000002494_03970;MGYG000002506_01938;MGYG000002534_03518;MGYG000002515_00714;MGYG000002502_00289;MGYG000000235_01041;MGYG000002323_02956 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,3X15C@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsI 1.0 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702 1.0 2.7.3.9 1.0 ko:K08483 1.0 ko02060,map02060 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--protein phosphotransferase. sugar--PEP phosphotransferase enzyme I. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 none 1.0 0 231269 121134 0 0 591392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493041 0 558148 0 0 0 0 0 0 0 0 294347 0 0 0 0 0 0 1116141 1254979 0 0 1933236 0 0 0 0 0 0 0 905129 0 0 0 0 1288120 0 0 2135998 0 0 0 0 0 0 0 0 0 0 1444319 0 0 0 0 1185689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 570345 0 634703 0 0 0 0 0 0 0 0 358776 0 0 0 0 0 0 443462 1063828 0 0 1141260 0 0 0 0 0 0 0 746988 0 0 0 0 960989 0 0 1175307 0 848064 0 0 0 0 0 0 0 0 988453 0 0 0 0 1043468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVIETM(Oxidation)EKLDTSDPEYIK MGYG000000198_03147 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,21Y97@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVIHQDAIEAEGK MGYG000000133_00139 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 pgcA 1.0 - 1.0 5.4.2.2,5.4.2.8 1.0 ko:K01835,ko:K01840 1.0 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00114,M00549 1.0 R00959,R01057,R01818,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Alpha-amylase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). | phosphomannomutase. phosphoglucose mutase. | phosphomannose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. | alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. | alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 902282 0 0 0 0 0 0 0 0 607394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 813451 0 0 0 0 0 0 0 0 0 0 1223908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 933712 0 0 0 1231023 0 0 883568 0 621642 -(Gln->pyro-Glu)QVIMIDAAGPR MGYG000001300_01685 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1149@1|root,COG2878@1|root,COG1149@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,3WIFS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 electron transport complex, RnfABCDGE type, B subunit 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_13,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 356195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246078 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVIQFIDLSLITK MGYG000002506_00089;MGYG000002494_00829;MGYG000002515_00914 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,1RR4N@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 P 1.0 During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction 1.0 dps 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005623,GO:0006950,GO:0008150,GO:0008199,GO:0009289,GO:0009295,GO:0009605,GO:0009991,GO:0031667,GO:0042594,GO:0042802,GO:0042995,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0097159,GO:1901363 1.0 - 1.0 ko:K04047 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03036 1.0 - 1.0 - 1.0 - 1.0 Ferritin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208884 0 0 0 0 0 0 0 0 1904016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1740027 0 0 0 0 0 2704365 1058284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 743265 0 0 0 0 0 0 300621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVITSFAGLR MGYG000001564_01807;MGYG000002298_00538;MGYG000000038_01495;MGYG000000274_03210;MGYG000000280_01802;MGYG000000133_01814;MGYG000000404_00180;MGYG000004552_00557;MGYG000004691_01133;MGYG000001619_01503;MGYG000002312_03079;MGYG000001710_03464;MGYG000000171_00187;MGYG000000255_01681;MGYG000001493_05221;MGYG000001186_01771;MGYG000002290_01418;MGYG000000271_03444;MGYG000001683_00852;MGYG000002186_01068;MGYG000004548_00016;MGYG000000909_00226;MGYG000000301_00532;MGYG000000252_02426;MGYG000002517_00473;MGYG000001311_02981;MGYG000000489_00238;MGYG000000154_01590;MGYG000000076_01007;MGYG000000153_02080;MGYG000004087_02481;MGYG000000249_02126;MGYG000000245_01076;MGYG000000205_00110;MGYG000002276_00835;MGYG000003074_00570;MGYG000001622_01941;MGYG000000127_02775;MGYG000000179_02173;MGYG000002279_02522;MGYG000001315_01114;MGYG000004271_01228;MGYG000002105_01104;MGYG000000212_00378;MGYG000000198_04022 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 0.28888888888888886 186801|Clostridia 1.0 S 0.6222222222222222 FAD dependent oxidoreductase 0.5111111111111111 - 0.8666666666666667 - 1.0 1.1.5.3 0.9777777777777777 ko:K00111 0.9777777777777777 ko00564,ko01110,map00564,map01110 0.9777777777777777 - 1.0 R00848 0.9777777777777777 RC00029 0.9777777777777777 ko00000,ko00001,ko01000 0.9777777777777777 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 0.9777777777777777 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 0.9777777777777777 0.9777777777777777 0.9777777777777777 0.9777777777777777 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 0.9777777777777777 none 1.0 2401576 1266365 1429388 2392344 1774960 1423058 1360454 2947247 1928160 3103204 1909802 2520760 1789561 1932289 2728436 1619848 1979290 0 2369504 2605827 2539577 1483359 0 743628 2285591 1975988 2218994 0 1838952 3015369 550335 840699 860707 2334313 2437947 1819449 1931230 869933 846936 716117 436422 1403684 594579 559862 702248 1157479 760146 972603 615772 509455 821105 784500 830116 447613 551177 0 903491 1052190 602655 310838 0 727288 1165794 935490 860002 0 1032298 608632 869832 628964 396143 908257 1084805 783695 755104 402840 2201681 914203 693088 1662656 384933 437882 1050197 1651970 1349840 1687458 791389 1303867 1091984 1986366 2256533 1230124 1205406 0 2004279 2334613 1613649 839735 0 383028 1638130 2054443 2715905 0 1606645 1763230 367965 950063 1111516 2024941 1337505 1476573 1865620 655262 2313593 638470 749835 2514261 1407854 896558 1189441 2751272 2976516 1650582 1064940 1676101 1068618 3212921 3021141 1315642 2084206 0 2363517 2271729 2517100 578944 0 541751 3073915 2483787 3335196 0 815422 2692987 742828 1195137 821070 1668765 2553764 2016579 2933746 756900 4691390 3231672 5044061 1458245 2791827 4322983 3874662 2838806 5316878 6853824 3952403 5502816 1834583 7694496 7061430 3085901 5442718 0 4820897 3785805 4893928 3904322 0 3722044 7312979 6011097 5950727 0 3363452 3825513 3708348 1473786 5780895 6160526 4375824 6943599 7943615 4775290 -(Gln->pyro-Glu)QVITSFAGNR MGYG000002492_02355;MGYG000002517_00257 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 565250 0 0 321512 0 0 449062 0 0 509056 0 0 312418 0 428386 0 276448 0 0 0 0 323463 401153 0 0 0 0 0 0 0 591056 0 211768 0 0 473680 0 0 0 0 0 0 0 0 0 0 307877 245707 0 0 0 0 0 0 0 0 0 0 0 0 376780 0 0 0 0 0 0 0 0 0 247716 0 0 239517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1742506 0 217909 0 0 0 943376 0 656962 0 1265912 0 0 0 0 0 852454 0 0 0 0 0 0 0 0 0 1109737 0 0 0 0 0 2382797 0 0 1813720 0 0 3288493 0 2091224 2130747 0 0 3252388 0 2843471 0 2143465 0 0 2304573 0 1815464 4099031 0 0 0 0 0 0 0 2056254 0 3877942 0 0 2597780 -(Gln->pyro-Glu)QVKM(Oxidation)RLAMEAIVAK MGYG000001157_00290;MGYG000003921_01842 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237767 0 0 0 0 144817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1411258 0 0 0 0 0 0 0 0 0 931261 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVLANEPVTVEK MGYG000002281_01027;MGYG000002549_03571;MGYG000000196_00200;MGYG000000013_00186;MGYG000003351_01202;MGYG000002478_00234;MGYG000004797_03276 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,2FMHI@200643|Bacteroidia,4AKEU@815|Bacteroidaceae 0.7142857142857143 976|Bacteroidetes 1.0 E 1.0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate 1.0 asd 1.0 - 1.0 1.2.1.11 1.0 ko:K00133 1.0 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00017,M00018,M00033,M00525,M00526,M00527 1.0 R02291 1.0 RC00684 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Semialdhyde_dh,Semialdhyde_dhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate-semialdehyde dehydrogenase. L-aspartate-beta-semialdehyde dehydrogenase. - L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Monobactam biosynthesis;Cysteine and methionine metabolism;Metabolic pathways;Lysine biosynthesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 804623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242660 0 0 0 0 0 0 0 0 0 0 495937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255313 0 0 0 0 0 0 0 0 0 0 312999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVLEEIPR MGYG000000179_00905;MGYG000004087_00017;MGYG000001311_05164;MGYG000002946_01793 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,21YF6@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204165 0 0 0 0 0 0 0 0 0 0 0 0 151334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226479 0 0 176094 0 0 0 0 0 0 0 0 0 71082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115862 0 0 161956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464765 0 0 718335 0 0 0 0 0 0 0 710582 0 -(Gln->pyro-Glu)QVLESLAPR MGYG000002545_01228;MGYG000003291_00547;MGYG000001300_00027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3WGQS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9,2.7.9.2 1.0 ko:K01007,ko:K08483 1.0 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060 1.0 M00173,M00374 1.0 R00199 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--protein phosphotransferase. | pyruvate, water dikinase. sugar--PEP phosphotransferase enzyme I. | pyruvate,water dikinase. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. | ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Phosphotransferase system (PTS);Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78288 0 0 295890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 871531 0 0 918823 0 0 0 0 813546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVLGTHVEQK MGYG000003693_01656;MGYG000002560_02698;MGYG000001789_00344;MGYG000002478_02005;MGYG000000243_02626 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,2FN1R@200643|Bacteroidia,4AMS5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 992023 0 843871 0 0 0 0 0 0 0 1175573 0 0 1160216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1067942 0 0 0 0 1109552 0 0 493893 0 505058 0 0 0 0 0 0 0 701901 0 0 236938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507305 0 0 0 0 527858 0 0 572649 0 738164 0 0 0 0 0 0 0 1025554 0 0 859401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472039 0 0 0 0 727678 0 0 373076 0 295718 0 0 0 0 0 0 0 0 0 0 258685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260423 0 0 289871 0 728468 0 0 0 0 0 0 0 1014236 0 0 887442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131923 0 0 0 0 373261 -(Gln->pyro-Glu)QVLKDDR MGYG000003683_01127 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4D10I@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit 1.0 rplX 1.0 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02895 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KOW,ribosomal_L24 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2046273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVLNQHPEVFDPR MGYG000000164_02284 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZPJ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG0191 Fructose tagatose bisphosphate aldolase 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 935378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVM(Oxidation)AQLGLK MGYG000000031_02924;MGYG000000252_02294;MGYG000002966_00348;MGYG000002298_02773;MGYG000004733_01681;MGYG000000171_01273;MGYG000000142_01607;MGYG000000806_00435;MGYG000002298_00038 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3XZRB@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 0.6666666666666666 - 0.6666666666666666 - 1.0 4.1.2.17 1.0 ko:K01628 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R02262 1.0 RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fuculose-phosphate aldolase. L-fuculose-1-phosphate lactaldehyde-lyase. - L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVMAQLGLK MGYG000000031_02924;MGYG000000252_02294;MGYG000002966_00348;MGYG000002298_02773;MGYG000004733_01681;MGYG000000171_01273;MGYG000000142_01607;MGYG000000806_00435;MGYG000002298_00038 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3XZRB@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 0.6666666666666666 - 0.6666666666666666 - 1.0 4.1.2.17 1.0 ko:K01628 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R02262 1.0 RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fuculose-phosphate aldolase. L-fuculose-1-phosphate lactaldehyde-lyase. - L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 114180 0 0 0 0 0 0 0 354297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169091 0 0 0 0 0 0 0 88910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337532 0 0 0 0 0 0 0 366716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692839 0 0 0 0 341034 -(Gln->pyro-Glu)QVMAQLGMK MGYG000001338_00134;MGYG000000200_00392;MGYG000000133_00165;MGYG000000212_01008;MGYG000000301_01359 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3WHFE@541000|Ruminococcaceae 0.6 186801|Clostridia 1.0 G 1.0 L-fuculose phosphate aldolase 0.6 fucA 0.6 - 1.0 4.1.2.17 1.0 ko:K01628 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R02262 1.0 RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fuculose-phosphate aldolase. L-fuculose-1-phosphate lactaldehyde-lyase. - L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 157739 106396 328429 163315 0 0 0 77766 0 196002 98607 0 168618 236469 91675 154826 121881 0 0 0 0 0 0 0 0 0 109851 0 299624 0 0 175803 112699 0 0 0 0 234943 146686 222392 80754 102591 0 0 232707 104965 0 0 66257 0 79580 92227 79580 0 107395 0 0 0 0 0 0 0 0 75861 194619 0 161155 0 258783 86782 0 0 0 0 64602 0 85989 391692 212934 0 0 0 0 60447 84222 192326 108551 0 0 114196 203570 278171 308276 0 0 0 0 0 0 0 0 339326 194780 0 112889 0 0 329123 356257 0 0 0 106602 196809 0 0 0 0 0 0 0 57482 0 123544 0 0 0 0 93185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92511 0 0 0 0 0 0 778226 845529 739364 1043301 0 0 903272 610164 537145 1052973 1068153 0 757462 1069183 801501 624443 823860 0 0 0 0 0 0 0 0 728503 855793 0 1123767 0 727940 1035535 1237575 0 0 759070 666643 740196 -(Gln->pyro-Glu)QVMIIYAATNK MGYG000002517_03148 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218032 0 0 0 0 358125 -(Gln->pyro-Glu)QVNIPSYLVK MGYG000002989_00885;MGYG000000389_02466;MGYG000003695_00624;MGYG000000249_01525;MGYG000002202_01331;MGYG000000271_01088;MGYG000000206_01061;MGYG000001374_01170;MGYG000001698_04057;MGYG000002517_02847;MGYG000004271_00043;MGYG000000404_01611;MGYG000003335_01405;MGYG000004842_00283;MGYG000004296_00416;MGYG000001310_00114;MGYG000002145_00311 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia 0.4117647058823529 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 115841 0 0 141698 184328 394145 0 0 0 109538 0 106661 0 0 0 0 0 0 0 354424 0 147397 0 0 325987 0 0 0 0 0 88662 0 225224 0 0 96602 0 0 86444 0 0 99898 192211 173138 0 0 0 68844 0 125033 0 0 0 0 0 0 0 113237 0 0 0 0 211051 0 0 0 0 0 78205 0 107323 0 0 88241 0 0 184821 0 0 215716 100865 108246 0 0 0 187845 0 283100 0 0 0 0 0 0 0 153797 0 0 0 0 142475 0 0 0 0 0 91966 0 250488 0 0 189763 0 0 147859 0 0 256888 331702 684443 0 0 0 283268 0 739879 0 0 0 0 0 0 0 0 0 77399 0 0 587555 0 0 0 0 0 191546 0 729105 0 0 162351 0 0 921592 0 0 649775 848654 629144 0 0 0 956677 0 983762 0 0 0 0 0 0 0 696336 0 529161 0 0 685595 0 0 0 0 0 729224 0 653734 0 0 649083 -(Gln->pyro-Glu)QVNVPR MGYG000000042_01421;MGYG000004757_00594;MGYG000004464_00178;MGYG000000138_00665;MGYG000002603_01782;MGYG000001630_01142;MGYG000004848_00666;MGYG000003353_00058;MGYG000000074_01773;MGYG000003460_01161;MGYG000000215_00564;MGYG000001925_01419;MGYG000000273_00431;MGYG000004763_01689;MGYG000003681_02037;MGYG000003202_00129;MGYG000001503_00139;MGYG000002281_02290;MGYG000000357_02040;MGYG000001770_01653;MGYG000003546_00955;MGYG000003992_01709;MGYG000003446_00658;MGYG000001552_00984;MGYG000001313_00097;MGYG000004629_00424;MGYG000000013_02251;MGYG000003542_01415;MGYG000003691_01713;MGYG000003697_01485;MGYG000000348_00283;MGYG000001655_02933;MGYG000000044_01721;MGYG000001360_01239;MGYG000002834_01866;MGYG000003152_01866;MGYG000002930_00867;MGYG000000196_03974;MGYG000004588_00463;MGYG000002905_00001;MGYG000001661_02666;MGYG000003374_00521;MGYG000002762_01733;MGYG000003424_00456;MGYG000001789_00154;MGYG000000054_03933;MGYG000002293_00521;MGYG000003701_03123;MGYG000000098_02017;MGYG000002291_02272;MGYG000002080_00527;MGYG000004474_01617;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000001346_01533;MGYG000000243_01988;MGYG000001562_01075;MGYG000002540_03367;MGYG000001763_00317;MGYG000000254_02569;MGYG000003279_00951;MGYG000003812_01875;MGYG000003497_00215;MGYG000004754_01565;MGYG000000414_00662;MGYG000002418_00753;MGYG000000117_01463;MGYG000003535_00219;MGYG000000168_03211;MGYG000000673_00997 class d__Bacteria|p__Bacteroidota|c__Bacteroidia 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.39436619718309857 976|Bacteroidetes 0.971830985915493 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.971830985915493 tuf 1.0 - 0.971830985915493 - 1.0 ko:K02358 0.971830985915493 - 0.971830985915493 - 0.971830985915493 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.971830985915493 - 0.971830985915493 - 1.0 - 0.971830985915493 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.971830985915493 none 1.0 751499 1024103 1048639 487577 1472008 1045506 881565 965148 878681 740305 970212 916482 1501235 1108720 1312777 1238999 844781 443837 494645 946482 1913328 1484127 1318428 1688836 1074170 1521102 1151174 1054209 781460 1281710 1458691 1234282 1659225 1022366 1471014 1286017 1387236 1462623 1876267 903699 2007349 1236498 1841979 1286056 1257939 1942945 1858714 2434787 0 1601121 1713426 1531085 2876178 2908041 770852 1936067 1978172 1931669 2487501 1506483 1599604 786964 1718665 1699741 1291153 1490649 924479 1334884 407656 265992 2247769 1620938 2506357 1484905 1682476 2626886 1227503 397605 451078 1093146 1771157 1085624 1461070 1396383 1154373 1288849 2141694 971250 1377880 1414084 996610 1530167 1765065 2391690 1077191 954815 1457560 1118362 1995621 2098019 1171994 1398100 1119482 1458548 1645019 1686367 1596500 1442114 1335513 1228380 1272136 1315740 1111231 959884 1191576 1501301 618674 1012321 1687733 1959301 1008837 1071957 936434 1187353 2180883 1888127 1894053 1173436 1481567 1756867 671911 1681745 1097311 1064102 1199567 1780428 2386291 1810214 804263 888290 1098260 303324 1086827 1437473 1606871 1945259 2370837 1464702 1477168 1716364 1616503 1771243 1786630 1529089 1614397 1435332 4213135 2417068 1782380 1819786 2005209 1640386 2422776 2226271 1667951 602634 1616568 2761214 2312226 1935466 1924978 2349995 2118021 1826407 1373673 676758 773662 2526712 855501 1250149 1544432 2576608 1184134 2161096 563237 1061098 842888 699818 678271 1353368 -(Gln->pyro-Glu)QVNVPYIVVFMNK MGYG000000249_00026 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2654912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVNYTVQTAC(Carbamidomethyl)HPLDVK MGYG000000224_00262;MGYG000003681_00233 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG3717@1|root,COG3717@2|Bacteria,4NDUV@976|Bacteroidetes,2FMP5@200643|Bacteroidia,4AM3B@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate 1.0 kduI 1.0 - 1.0 5.3.1.17 1.0 ko:K01815 1.0 ko00040,map00040 1.0 - 1.0 R04383 1.0 RC00541 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 KduI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 5-dehydro-4-deoxy-D-glucuronate isomerase. 5-keto-4-deoxyuronate isomerase. The enzyme is involved in the degradation of polygalacturonate, a later stage in the degradation of pectin by many microorganisms. 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 859960 1087585 0 742716 0 1110952 1377242 1181482 0 1069599 0 1334771 0 0 0 0 0 917559 0 994548 0 730272 0 0 0 0 0 0 0 0 496484 0 0 0 0 856729 0 0 0 0 0 0 0 0 0 0 0 309524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721688 794337 400197 0 0 0 1052002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641183 0 0 530008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVPDSTEIRVDKVTGTLIR MGYG000000223_02386 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,3VPI5@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 669382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 357764 0 375674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 734979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVPDTAEIKIDPVTNTLIR MGYG000001714_01486 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus_A|s__Coprococcus_A catus|m__MGYG000001714 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27M97@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF,SSF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 323369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVPDTKGGVK MGYG000001637_02230;MGYG000000087_01268;MGYG000001367_03001;MGYG000001615_04300;MGYG000002141_01824;MGYG000000255_01557;MGYG000000489_01026;MGYG000001617_02046;MGYG000000077_02468;MGYG000004719_02002;MGYG000000997_00555;MGYG000001777_01059;MGYG000000312_02426;MGYG000002445_02276;MGYG000002528_02668;MGYG000003702_03102;MGYG000004359_01906;MGYG000000028_00944;MGYG000000271_02101;MGYG000000404_01798;MGYG000000398_00614;MGYG000002492_00660;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000003486_02521;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.48148148148148145 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.48148148148148145 etfB 1.0 - 0.9259259259259259 - 0.8148148148148148 ko:K03521 0.8148148148148148 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.8148148148148148 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8148148148148148 0.8148148148148148 0.8148148148148148 0.8148148148148148 1.0 none 1.0 925004 1112499 1389993 0 0 1614750 0 0 746091 1645543 0 1268502 2073980 1476889 0 0 0 0 1179419 0 0 1644508 0 596586 0 1169130 0 0 0 0 383488 0 929416 0 0 0 1034783 1257362 0 208847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220815 0 676524 3115953 1624096 0 0 937960 0 0 452712 675961 0 589632 1827023 658831 0 0 0 0 1623773 0 0 1858610 0 198187 0 780206 0 0 0 0 266828 0 1596150 0 0 0 483779 1007640 2765880 1875036 1833749 0 0 2484423 0 0 3591365 3922992 0 1628365 1141239 3804883 0 0 0 0 3773419 0 0 1370895 0 937078 0 2619275 0 0 0 0 1417476 0 2080444 0 0 0 3746932 2158300 310722 382051 1375016 0 0 1035045 0 0 603448 1394750 0 1281376 419590 855467 0 0 0 0 437238 0 0 411102 0 389155 0 799293 0 0 0 0 801587 0 1196209 0 0 0 2023243 1306877 -(Gln->pyro-Glu)QVPDTKGGVKFNPDGTLDR MGYG000001637_02230;MGYG000000271_02101;MGYG000000404_01798;MGYG000001777_01059;MGYG000000312_02426;MGYG000000154_01281;MGYG000002517_00543;MGYG000001319_02234;MGYG000002528_02668;MGYG000003702_03102 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.7 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.7 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVPDTKGGVQFNPDGTLNR MGYG000000164_00687;MGYG000004055_00051;MGYG000000127_04021;MGYG000001315_01867 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.75 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.75 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVPDTNEIKVDPVTHTLVR MGYG000000262_01290 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF,SSF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830589 0 0 0 0 335837 -(Gln->pyro-Glu)QVPDTSGKVAVNPDGTLNR MGYG000003589_02741;MGYG000002086_01704;MGYG000002057_00750 phylum d__Bacteria|p__Firmicutes_A 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,2N6RS@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVPDTSGKVSVKPDGTLDR MGYG000001300_00292 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WH8V@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1231097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 964742 0 0 0 0 796600 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVPDTSGVVAVKEDGTMDR MGYG000000099_01611 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,26915@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496477 0 0 0 0 0 0 683210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 512198 602730 0 0 0 0 0 0 0 0 0 503812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVPDTTEIKLDPVTGTLIR MGYG000004893_01403;MGYG000002485_00624;MGYG000004828_00743 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG2086@1|root,COG2086@2|Bacteria,378IK@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 778648 1426817 0 768714 2083907 785854 0 0 2148360 1814568 947710 1307979 523484 0 1898385 1190178 0 812275 0 692946 2145199 0 1526026 0 0 648426 0 0 1249833 1418805 869302 1491081 0 0 0 0 1194304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVPVMIHR MGYG000003372_03922;MGYG000002494_00951 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,3XNZY@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 GO:0000166,GO:0000900,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004812,GO:0004829,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006435,GO:0006446,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0017076,GO:0017148,GO:0019222,GO:0019538,GO:0019752,GO:0030371,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032553,GO:0032555,GO:0032559,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045947,GO:0046483,GO:0046872,GO:0046914,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097367,GO:0106074,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iPC815.YPO2433,iSDY_1059.SDY_1814 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 2863876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1611339 0 1453018 0 0 0 0 3016659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1349402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1119703 0 869942 0 0 0 0 1049977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1004764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4721662 0 509562 0 0 0 0 3629867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9796568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15117400 0 3906881 0 0 0 0 133076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVQHLVKVEE MGYG000000184_01190;MGYG000001338_02789;MGYG000000301_00178;MGYG000000133_00063;MGYG000000200_01095;MGYG000000213_00196 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,3Y0NM@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein L30p/L7e 1.0 rpmD 1.0 - 1.0 - 1.0 ko:K02907 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L30 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 720772 523771 0 0 0 418799 0 0 0 1362788 977033 0 0 0 0 304891 0 0 0 0 653559 0 0 663769 0 0 684805 0 0 393757 0 0 0 0 433007 0 861828 0 0 0 0 0 0 0 0 0 0 0 184092 0 0 0 0 329856 0 0 0 0 0 0 0 0 0 0 0 0 0 462285 0 0 0 0 298277 0 0 0 0 1131476 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563116 670829 0 0 0 0 0 0 0 896043 0 0 0 0 0 0 0 0 413326 341383 0 422414 0 542932 520900 0 0 322559 0 0 0 418548 0 0 606404 0 265243 0 0 0 0 0 0 0 508073 0 0 331785 0 0 0 0 0 0 349501 568003 3944881 2833091 3323111 4988933 0 3020998 4486436 0 0 4564720 2485073 0 2169736 3736110 3649869 2871022 3949075 0 3400033 0 3828432 1811009 0 3358498 0 3417499 3371328 0 0 1694717 0 0 3239885 4924453 2650692 0 2921977 2828121 -(Gln->pyro-Glu)QVQTGDKFVVR MGYG000002560_04324 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp902388365|m__MGYG000002560 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 9378810 0 0 0 0 5469452 0 0 0 0 0 0 0 7073532 0 0 0 0 4665487 0 0 0 0 5974499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1761462 0 0 0 0 0 0 0 1061847 0 0 0 0 1025795 0 0 0 0 2042747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314652 0 0 0 0 194672 0 0 0 0 0 0 0 458561 0 0 0 0 0 0 0 0 0 759831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 549842 0 0 0 0 0 0 0 0 0 306446 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVRPGLC(Carbamidomethyl)K MGYG000001338_03091;MGYG000000002_03130;MGYG000002312_00094;MGYG000000038_02498;MGYG000000251_02538;MGYG000000146_03079;MGYG000000262_02904;MGYG000000249_02227;MGYG000000195_00356;MGYG000002212_01534;MGYG000002772_00865;MGYG000000200_01731;MGYG000002040_00491;MGYG000001315_01504 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia 0.7857142857142857 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 0.7857142857142857 pgcA 1.0 - 1.0 5.4.2.2,5.4.2.8 1.0 ko:K01835,ko:K01840 1.0 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00114,M00549 1.0 R00959,R01057,R01818,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). | phosphomannomutase. phosphoglucose mutase. | phosphomannose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. | alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. | alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 1436736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1718812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2126479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2149714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVSAVKEAK MGYG000000243_01586 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0AS@200643|Bacteroidia,4AMX1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MbeB_N,TPR_1,TPR_11,TPR_16,TPR_17,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 2041257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1576212 0 0 0 0 1990524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVSPGVLALR MGYG000000255_00876;MGYG000000233_02977 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG1775@1|root,COG1775@2|Bacteria,1TS7H@1239|Firmicutes,2493U@186801|Clostridia,21YHW@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 2-hydroxyglutaryl-CoA dehydratase, D-component 1.0 fldB 1.0 - 1.0 1.3.7.8,4.2.1.167 1.0 ko:K04113,ko:K20903 1.0 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 1.0 M00541 1.0 R02451 1.0 RC00002,RC01839 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HGD-D 1.0 - 1.0 - 1.0 - 1.0 - 1.0 benzoyl-CoA reductase. | (R)-2-hydroxyglutaryl-CoA dehydratase. - Inactive toward aromatic acids that are not CoA esters but will also catalyze the reaction: NH3 + acceptor + 2 ADP + 2 phosphate = hydroxylamine + reduced acceptor + 2 ATP + H2O.-!-In the presence of reduced acceptor, but in the absence of oxidizable substrate, the enzyme catalyzes the hydrolysis of ATP to ADP plus phosphate.-!-Formerly EC 1.3.99.15. | The enzymes from the bacteria Acidaminococcus fermentans and Clostridium symbiosum are involved in the fermentation of L-glutamate.-!-The enzyme contains [4Fe-4S] clusters, FMNH2 and riboflavin.-!-It must be activated by a an activator protein.-!-Once activated, it can catalyze many turnovers. 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized 2[4Fe-4S]- [ferredoxin] + 2 phosphate = 2 ATP + benzoyl-CoA + 2 H2O + reduced 2[4Fe- 4S]-[ferredoxin]. | (R)-2-hydroxyglutaryl-CoA = (2E)-glutaconyl-CoA + H2O. 1.0 1.0 1.0 1.0 Degradation of aromatic compounds;Metabolic pathways;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 201209 552006 0 0 0 0 0 0 0 362333 252273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220701 0 340723 0 0 186223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127727 0 0 0 -(Gln->pyro-Glu)QVSVYPR MGYG000001065_00187;MGYG000000909_01199;MGYG000001311_00863;MGYG000001954_01693;MGYG000003366_00085;MGYG000003074_02174;MGYG000001531_02379;MGYG000000179_02646;MGYG000001367_01068;MGYG000000172_00061;MGYG000004691_02150;MGYG000001617_02395;MGYG000000198_03197 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,220IA@1506553|Lachnoclostridium 0.6923076923076923 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL27 family 0.6923076923076923 rpmA 0.7692307692307693 - 1.0 - 1.0 ko:K02899 0.7692307692307693 ko03010,map03010 0.7692307692307693 M00178 0.7692307692307693 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.7692307692307693 - 1.0 - 1.0 - 1.0 Ribosomal_L27 0.7692307692307693 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.7692307692307693 none 1.0 183142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170395 0 0 0 0 0 0 0 0 0 0 0 0 93320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294567 0 406999 0 0 0 0 0 0 387340 0 0 0 0 0 0 0 0 0 0 508395 0 -(Gln->pyro-Glu)QVTDGPAAENAK MGYG000000074_01070 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG0457@2|Bacteria,4PESY@976|Bacteroidetes,2G21B@200643|Bacteroidia,22UIH@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 624221 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVTEKAEK MGYG000002478_04136;MGYG000002549_02639;MGYG000004899_02720;MGYG000001378_01963;MGYG000000236_03832;MGYG000000196_03151;MGYG000001346_01418 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 1281214 0 1388561 1044643 0 0 0 1198136 0 0 0 0 0 0 0 0 0 0 0 1165903 0 1207375 0 0 0 0 0 1359427 0 0 1678284 0 0 0 0 901977 0 0 936627 0 994268 632068 0 0 0 947097 0 0 0 0 0 0 0 0 0 0 0 750761 0 566496 0 0 0 0 0 480998 0 0 522695 0 0 0 0 351754 0 0 1005521 0 988228 1101321 0 0 0 742520 0 0 0 0 0 0 0 0 0 0 0 604502 0 745988 0 0 0 0 0 473855 0 0 552004 0 0 0 0 599561 0 0 863334 0 662294 617727 0 0 0 662729 0 0 0 0 0 0 0 0 0 0 0 427674 0 452310 0 0 0 0 0 635605 0 0 613232 0 0 0 0 534546 0 0 469395 0 571459 509572 0 0 0 401717 0 0 0 0 0 0 0 0 0 0 0 259218 0 646377 0 0 0 0 0 247086 0 0 383532 0 0 0 0 665880 -(Gln->pyro-Glu)QVVDKTK MGYG000000074_01205 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,22U5S@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272598 0 0 0 0 326296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164428 0 625975 0 604847 0 0 0 0 0 0 0 0 0 0 968930 0 -(Gln->pyro-Glu)QVVEEEVK MGYG000000179_03221 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24R6P@186801|Clostridia,220KI@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582839 0 628785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490593 0 0 0 0 0 0 0 0 0 0 460954 0 -(Gln->pyro-Glu)QVVIC(Carbamidomethyl)GSQYSGEIKK MGYG000000077_01765;MGYG000000262_01556 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,25VG1@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 177742 0 372201 0 0 0 0 0 0 0 0 0 0 0 341577 0 0 0 0 0 0 0 0 0 0 0 279718 0 0 0 0 0 0 0 0 0 0 695331 0 0 0 0 0 0 0 0 0 0 0 373927 275691 0 0 0 351625 0 0 318513 0 0 0 0 0 0 265609 425041 0 0 0 0 0 0 1360665 0 435741 0 784990 0 729523 0 0 0 0 857466 0 0 0 996163 866851 0 932588 0 0 0 0 1035171 0 0 0 0 0 0 1020996 1080097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVVTAAADGAIAATQAEK MGYG000001315_00850 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,27IZT@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Pyridine nucleotide-disulphide oxidoreductase 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 497559 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 786533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVVTVAGDTK MGYG000001306_03308;MGYG000001783_02428 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 387583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 979562 0 0 0 0 756903 0 0 0 0 1658239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 615689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVYAFGAGTKK MGYG000001367_03018;MGYG000000262_02240 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,220DE@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 1.0 Acetyl-CoA hydrolase/transferase C-terminal domain 0.5 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 588500 0 0 0 623815 0 627225 0 0 0 0 0 0 0 0 0 0 0 0 0 717673 0 360540 0 0 0 0 0 0 0 0 0 353608 367982 0 0 0 0 353768 0 0 0 0 0 270254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386970 0 0 0 0 0 0 0 0 0 318762 571194 0 0 0 0 1531558 0 0 0 713248 0 1102594 0 0 0 0 0 0 0 0 0 0 0 0 0 1289403 0 291662 0 0 0 0 0 0 0 0 0 1447077 1243606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397100 0 0 0 726582 0 482465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 978790 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVYAFGAGTQK MGYG000003937_01094;MGYG000002272_01500;MGYG000001300_00298;MGYG000003166_01331;MGYG000002641_00051;MGYG000000022_01327;MGYG000002040_01712;MGYG000002545_00551;MGYG000002619_02242;MGYG000003899_01139 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,3WGGE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acetyl-CoA hydrolase/transferase C-terminal domain 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1108998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1224038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVYGFGAGTKK MGYG000000271_00943;MGYG000004414_01832;MGYG000004271_01186 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Acetyl-CoA hydrolase transferase 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 1566136 0 0 0 0 0 0 0 0 0 0 0 2369087 0 0 0 0 2342900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 979969 0 0 0 0 1045686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 542761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1062894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 892083 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVYGNANLYNK MGYG000002494_04543;MGYG000002506_02163;MGYG000002515_00391 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1652@1|root,COG1652@2|Bacteria,1RD8K@1224|Proteobacteria,1S4CB@1236|Gammaproteobacteria,3XPJS@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 1.0 S 1.0 response to potassium ion 0.6666666666666666 ygaU 1.0 GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BON,LysM 1.0 - 1.0 - 1.0 CBM50 1.0 - 0.6666666666666666 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 462259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379175 0 571024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1241919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1182172 0 841225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QVYVLTKDEGGR MGYG000001615_01716;MGYG000000171_02844;MGYG000002279_01932;MGYG000001673_01975;MGYG000000201_03875;MGYG000000245_03248;MGYG000001688_04229;MGYG000000930_01271;MGYG000000280_01200;MGYG000002926_00232;MGYG000001714_01291;MGYG000000198_01165;MGYG000000392_00966;MGYG000000271_03365;MGYG000001315_01207;MGYG000000133_02991;MGYG000004879_01608;MGYG000003273_00234;MGYG000000140_01590;MGYG000001065_02730;MGYG000002994_01317;MGYG000002528_01098;MGYG000000263_00836;MGYG000003899_01642;MGYG000000179_00920;MGYG000000216_02406;MGYG000001563_01273;MGYG000002980_01277;MGYG000002517_00205;MGYG000001531_00906;MGYG000004296_01668;MGYG000001607_01045;MGYG000001141_02439;MGYG000001809_00576;MGYG000001652_01300;MGYG000000127_03982;MGYG000003425_03741;MGYG000000258_00266;MGYG000000251_00064;MGYG000001338_03373;MGYG000002670_00364;MGYG000001300_00280;MGYG000000233_00807;MGYG000000142_00171;MGYG000002702_01978;MGYG000000255_02009;MGYG000002040_01212;MGYG000004087_00551;MGYG000000242_00282;MGYG000002143_01659;MGYG000003266_00955;MGYG000002417_01244;MGYG000000164_01096;MGYG000002794_01318;MGYG000000187_02029;MGYG000000202_03457;MGYG000000212_03313;MGYG000001698_04050;MGYG000003074_01359;MGYG000001777_01732;MGYG000002212_00196;MGYG000000249_00026;MGYG000004799_01385;MGYG000002136_02858;MGYG000004630_01824;MGYG000000262_00030;MGYG000003486_01055;MGYG000002772_01895;MGYG000002492_00344;MGYG000001617_01406;MGYG000002057_01066;MGYG000002052_00232;MGYG000004475_00887;MGYG000001086_01249;MGYG000000206_00901 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.21333333333333335 186801|Clostridia 0.9733333333333334 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 936182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2005113 0 0 0 0 0 0 0 0 0 0 0 0 0 1679268 0 0 0 0 1175175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1668469 0 1470358 0 0 0 0 0 0 0 0 1825600 0 0 1493465 0 0 0 1902755 0 0 0 0 0 0 1416832 0 0 0 1762801 0 0 1835003 0 0 0 1569919 1515233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QWDKGQQVIFEANPDYYGEEPK MGYG000000133_03036 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 651552 932475 0 0 0 0 0 0 0 639889 0 1107477 771454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1240416 0 0 0 0 463657 -(Gln->pyro-Glu)QWGFENVHC(Carbamidomethyl)VPEQMVK MGYG000000243_01121 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QWGFENVHTVPEQMVK MGYG000002478_04136 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 322402 533191 0 393353 595488 0 0 0 647003 0 0 0 490185 326808 0 488752 0 382154 330085 308789 0 0 584086 0 0 288499 753334 0 532381 544041 0 615733 350462 0 559905 0 401929 369460 458068 549817 467603 659794 684919 0 0 836526 493255 0 0 679483 710019 713961 0 618855 0 0 740867 615191 0 0 786458 0 0 789758 754258 754115 638437 583744 0 612395 515304 357859 615721 0 586786 392716 545591 997507 415952 651078 461559 0 0 307276 390257 0 0 618307 0 329403 0 0 0 0 700846 339769 0 0 731919 0 0 0 547481 615587 373023 246745 0 0 329791 819175 0 0 485824 314103 0 0 0 325284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402947 606027 0 0 484417 423240 0 0 143575 401367 291652 0 205545 0 1119371 306466 800198 0 0 1130853 0 0 572942 402934 1361420 528544 493343 0 0 353833 666046 820702 0 423560 460620 -(Gln->pyro-Glu)QWGSPTPGHPEVDIMR MGYG000001306_00741;MGYG000002560_01049;MGYG000002549_01292;MGYG000001378_04775;MGYG000000196_00739;MGYG000002478_02451;MGYG000001461_03636;MGYG000004797_01102 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia,4AKPQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Belongs to the transketolase family 1.0 tkt 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 795907 0 764500 0 0 0 0 0 888927 0 817106 0 0 0 0 633596 0 0 0 0 744365 0 0 0 0 515324 0 0 0 0 510956 0 0 0 0 747082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330295 0 436596 0 0 0 0 0 364098 0 517646 0 0 0 0 777412 0 0 0 0 717558 0 0 0 0 753068 0 0 0 0 0 0 0 0 0 314611 -(Gln->pyro-Glu)QWGSVTPGHPELDLQR MGYG000002080_01068;MGYG000002293_00078;MGYG000003697_02025 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the transketolase family 1.0 tkt 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 584632 0 611105 556191 0 513460 0 0 611160 446509 464063 0 0 564592 426237 1683588 0 0 0 696192 2266181 527433 0 0 0 2030077 0 0 0 0 657965 484161 398409 0 0 599023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QWNHEQR MGYG000000003_02056;MGYG000003279_02071 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 2559216 0 0 1796140 0 0 2196757 0 2313322 869844 0 0 0 2347225 1504545 0 0 0 3034621 2980260 0 0 0 0 1633717 2390804 0 0 0 0 0 0 0 0 0 2336452 1922586 0 157587 0 0 357162 0 0 412726 0 491910 264313 0 0 0 366458 112797 0 0 0 446743 141428 0 0 0 0 347629 287382 0 0 0 0 0 0 0 0 0 124264 265380 0 349219 0 0 0 0 0 153297 0 407393 149512 0 0 0 167070 0 0 0 0 333505 183400 0 0 0 0 476733 166042 0 0 0 0 0 0 0 0 0 401873 397136 0 0 0 0 181180 0 0 505827 0 175430 205619 0 0 0 185224 283059 0 0 0 552837 0 0 0 0 0 288542 321939 0 0 0 0 0 0 0 0 0 287376 0 0 0 0 0 90784 0 0 0 0 0 0 0 0 0 4031960 308444 0 0 0 0 0 0 0 0 0 178156 334370 0 0 0 0 0 0 0 0 0 0 164533 0 -(Gln->pyro-Glu)QWSVDFDGDGAHSDN(Deamidated)GR MGYG000002485_00658 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 2EYI9@1|root,33RS4@2|Bacteria,37BMK@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2298319 0 0 0 0 0 0 574865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QWSVDFDGDGAHSDNGR MGYG000002485_00658 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 2EYI9@1|root,33RS4@2|Bacteria,37BMK@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4860263 0 0 0 0 0 0 918720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QWTDMLQASK MGYG000000029_00388;MGYG000001345_03249;MGYG000003351_05247;MGYG000001378_04109;MGYG000000054_02624;MGYG000002549_04149;MGYG000003312_03104;MGYG000000013_01887;MGYG000004899_02709 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2152@1|root,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,2FPFW@200643|Bacteroidia,4APF0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG NOG16664 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1080 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 407600 0 0 359456 0 0 0 0 0 0 931390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168132 0 0 0 0 0 0 114054 0 191103 118342 0 287455 0 0 0 0 0 0 786496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305466 0 0 0 0 0 0 243050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 706176 240443 0 408278 0 0 0 0 0 0 488857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 200537 0 300353 0 0 0 0 165372 0 136504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QWTHGGVVFAPVPR MGYG000004271_00017;MGYG000000245_02639;MGYG000002517_02872;MGYG000000271_01062;MGYG000004719_01259 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513820 0 0 0 0 0 0 610657 0 0 0 0 0 0 0 0 0 0 0 933208 0 779324 0 0 0 0 0 0 0 0 0 0 0 0 0 442876 0 786383 901364 0 0 0 828909 0 0 1027084 0 0 0 0 0 0 0 0 0 0 0 1305784 0 1054768 0 0 0 0 0 0 0 0 0 0 0 0 0 940737 0 1117609 2243522 0 0 0 1304758 -(Gln->pyro-Glu)QYAAVLAVAK MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG3209@1|root,COG3209@2|Bacteria,1TRJ1@1239|Firmicutes,24AU6@186801|Clostridia,3WHF3@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 M 1.0 COG3209 Rhs family protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Big_2,Flg_new,Fn3_assoc,LRR_5,Lipase_3,N_methyl,Peptidase_M15_4,Transglut_core 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286295 0 0 0 0 0 0 -(Gln->pyro-Glu)QYAGFSTAEESNAFYR MGYG000002575_01112;MGYG000000029_00452;MGYG000003367_01505;MGYG000002205_01528;MGYG000002549_04227;MGYG000003449_01192;MGYG000001346_00857;MGYG000000053_01401;MGYG000002418_00781;MGYG000001370_02456;MGYG000004464_01736;MGYG000004658_00971;MGYG000000098_00635;MGYG000004769_01857;MGYG000003693_01258;MGYG000001412_02065;MGYG000000273_01824;MGYG000001783_00897;MGYG000001551_03344;MGYG000003279_00971;MGYG000000414_00242;MGYG000003908_01540;MGYG000004763_00641;MGYG000001345_03358;MGYG000000243_02184;MGYG000004158_00691;MGYG000004822_01122;MGYG000001378_04187;MGYG000002171_02052;MGYG000002007_01203;MGYG000000196_02288;MGYG000002113_00130;MGYG000004006_00254;MGYG000000254_00655;MGYG000003363_01960;MGYG000003542_00863;MGYG000003649_00955;MGYG000003469_00358;MGYG000004501_01751;MGYG000001306_00281;MGYG000003312_00926;MGYG000001925_02121;MGYG000000138_02196;MGYG000001806_01383;MGYG000002478_00340;MGYG000001415_00892;MGYG000001365_00414;MGYG000000442_00346;MGYG000000074_01524;MGYG000000054_02932;MGYG000000003_01875;MGYG000002438_02292;MGYG000003681_00140;MGYG000000236_01415 domain d__Bacteria 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,4AMCS@815|Bacteroidaceae 0.4444444444444444 976|Bacteroidetes 0.8703703703703703 I 1.0 Psort location Cytoplasmic, score 8.96 0.4444444444444444 mutB 0.9629629629629629 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428666 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYAGFSTAEESNAFYRR MGYG000002575_01112;MGYG000000029_00452;MGYG000003367_01505;MGYG000002205_01528;MGYG000002549_04227;MGYG000003449_01192;MGYG000001346_00857;MGYG000000053_01401;MGYG000002418_00781;MGYG000001370_02456;MGYG000004464_01736;MGYG000004658_00971;MGYG000000098_00635;MGYG000004769_01857;MGYG000001412_02065;MGYG000000273_01824;MGYG000001783_00897;MGYG000001551_03344;MGYG000003279_00971;MGYG000000414_00242;MGYG000003908_01540;MGYG000004763_00641;MGYG000001345_03358;MGYG000000243_02184;MGYG000004158_00691;MGYG000004822_01122;MGYG000001378_04187;MGYG000002171_02052;MGYG000002007_01203;MGYG000000196_02288;MGYG000002113_00130;MGYG000004006_00254;MGYG000000254_00655;MGYG000003363_01960;MGYG000003542_00863;MGYG000003469_00358;MGYG000003312_00926;MGYG000001925_02121;MGYG000000138_02196;MGYG000001806_01383;MGYG000002478_00340;MGYG000001415_00892;MGYG000001365_00414;MGYG000000442_00346;MGYG000000074_01524;MGYG000000054_02932;MGYG000000003_01875;MGYG000002438_02292;MGYG000003681_00140;MGYG000000236_01415 domain d__Bacteria 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,4AMCS@815|Bacteroidaceae 0.44 976|Bacteroidetes 0.88 I 1.0 Psort location Cytoplasmic, score 8.96 0.44 mutB 0.98 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYANATLLR MGYG000002438_02632;MGYG000000196_04526;MGYG000000029_01860;MGYG000001345_00467;MGYG000000044_01913;MGYG000002033_00099;MGYG000002478_01776;MGYG000000138_02337;MGYG000001372_03000;MGYG000000243_02506;MGYG000001346_02842;MGYG000003221_00520;MGYG000003681_01109;MGYG000001313_02623;MGYG000000174_01424;MGYG000000236_00428;MGYG000001599_01342;MGYG000004797_01374;MGYG000002540_01909 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia 0.3157894736842105 976|Bacteroidetes 1.0 G 0.6842105263157895 Fructose-1,6-bisphosphate aldolase, class II 0.3157894736842105 fba 0.6842105263157895 - 1.0 4.1.2.13 0.6842105263157895 ko:K01624 0.6842105263157895 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6842105263157895 M00001,M00003,M00165,M00167,M00344,M00345 0.6842105263157895 R01068,R01070,R01829,R02568 0.6842105263157895 RC00438,RC00439,RC00603,RC00604 0.6842105263157895 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6842105263157895 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6842105263157895 0.6842105263157895 0.6842105263157895 0.6842105263157895 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.6842105263157895 none 1.0 489493 951138 831031 765361 1037610 578073 1176048 694919 661553 717229 1174637 845326 1416679 597056 512344 1131807 585887 1138429 428090 441678 1202508 1017682 1526644 1042776 674505 724523 1214814 1179786 845827 984637 1140615 806813 1530823 731406 877951 948608 835493 1050520 1011349 846731 1177923 1270175 1868341 1147580 1186580 1246119 1217209 1487526 2001051 1526812 1861333 1347746 1144809 2453745 1119588 1056643 814416 0 1707318 1265537 2224929 815715 1210068 1247020 1235583 1668864 1122154 1475925 840747 726407 1178895 945170 0 0 913663 0 634968 1030371 1315912 589552 1704360 1053845 986859 714821 969214 508373 1271139 1317278 1075048 903158 707636 1251435 802987 2622058 700759 657937 941547 1214530 2795884 1525082 662342 0 653316 2873153 1014390 763272 1090424 994973 799310 429048 580060 1144547 614244 1008227 0 150612 0 0 0 0 213745 166616 0 0 232853 258947 487237 0 294016 235713 0 231007 0 223955 692893 179969 200574 0 0 319684 0 361053 0 187021 217152 154251 126445 389193 294717 310115 260492 0 741536 0 573412 612946 797108 1684739 1729250 1051384 1457992 928729 1448768 1483771 1190893 0 492121 1642119 1324461 2615340 731840 1252335 1828770 0 1862565 853823 857713 1061005 405343 2112342 0 2140903 981103 471132 443294 631780 0 565809 468913 1074352 -(Gln->pyro-Glu)QYANQTLLR MGYG000004468_00561;MGYG000002455_03337 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402865 0 0 0 0 329911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 612166 0 0 0 0 389275 0 0 0 0 239670 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYDDAIATFNK MGYG000002171_02152;MGYG000000243_01586;MGYG000002478_03786 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0AS@200643|Bacteroidia,4AMX1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MbeB_N,TPR_1,TPR_11,TPR_16,TPR_17,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 766126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1063383 0 0 0 0 839510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265237 0 0 0 0 0 -(Gln->pyro-Glu)QYDDRYHVLK MGYG000000077_02468;MGYG000003074_00586;MGYG000002141_01824;MGYG000000312_02426;MGYG000000262_02235;MGYG000003702_03102 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 0.6666666666666666 etfB 1.0 - 0.6666666666666666 - 0.6666666666666666 ko:K03521 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.6666666666666666 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 1.0 none 1.0 920098 1648074 1166998 578286 1936908 1560717 214536 1640941 606312 1657757 880943 1522750 1975825 1019598 1650459 1641846 1082114 0 1241461 1170943 903873 2095595 0 545666 1436820 776529 679229 0 638879 931499 466521 1137126 880315 923455 1017339 0 499414 781854 1386070 1169784 459542 984527 591495 816952 1800311 969003 1074410 765290 501877 526946 897875 564227 854393 327512 554525 0 997717 1079044 857741 564924 0 1355619 1021057 964159 1020376 0 1600345 904988 1074935 791744 456237 1225438 1205425 0 1179543 621307 3412622 6315657 1048727 6859588 424114 3620232 941028 3782291 1161141 4416858 1440009 1865463 2988706 2421188 4266176 3435303 2975887 0 4186710 4055126 2664527 5496247 0 1527295 5707773 3438746 4937722 0 758171 2802096 957431 4062973 2708239 5152992 5202242 0 3048368 866803 1402598 2092701 1148356 2520284 1530933 2099985 1937185 1449639 1624369 2307471 1312021 978785 2231864 1676998 1556068 3343744 2463964 0 1159214 2158499 1364834 1787587 0 1587538 1592506 1057532 1978502 0 1592324 1525331 990612 1354216 1648134 1095134 1457451 0 857524 1405290 0 717583 1017121 0 574785 1127239 517423 414213 307130 228987 1333534 474166 724148 268883 255482 823052 333392 0 352182 0 338459 1323845 0 935597 458629 231118 412973 0 0 178728 1302348 1403345 1362014 355757 401053 0 59044 802633 -(Gln->pyro-Glu)QYDEFFHR MGYG000001300_01892 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1073@1|root,COG1073@2|Bacteria,1UQS2@1239|Firmicutes,24F94@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 alpha beta 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AXE1,Abhydrolase_1,Chlorophyllase2,Hydrolase_4,Peptidase_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 539396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 676824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 785878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYEDEIKR MGYG000004479_01906;MGYG000001364_02120;MGYG000000042_01480;MGYG000003693_03030;MGYG000001306_00956 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2825@1|root,COG2825@2|Bacteria,4NWPA@976|Bacteroidetes,2G3DE@200643|Bacteroidia,4AWDW@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 M 1.0 Membrane 0.8 - 0.8 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 417837 0 0 0 0 0 0 0 0 0 0 0 211852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 785085 0 0 0 0 0 0 976076 0 0 0 0 1697291 0 0 0 0 1241671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYEDELQNLK MGYG000000179_04961;MGYG000000198_05763;MGYG000000650_00893;MGYG000004087_02269;MGYG000001065_01413;MGYG000001311_03457;MGYG000001531_02630 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,21ZWZ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 K 1.0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides 1.0 greA 1.0 - 1.0 - 1.0 ko:K03624 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03021 1.0 - 1.0 - 1.0 - 1.0 GreA_GreB,GreA_GreB_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYEDEMKR MGYG000002478_01528;MGYG000002171_01839;MGYG000002560_00092;MGYG000000243_03119;MGYG000004797_03114 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 2796049 1559014 2343546 1445369 0 1011086 1062649 0 984085 0 2819919 0 1198525 2906730 0 0 0 0 1323838 1254462 0 1368504 1118000 0 0 0 1116121 1364804 2011973 0 2775262 0 1535835 1068012 0 2591858 0 0 1018631 1027758 1213147 977729 0 1260467 844290 0 1051535 0 1782643 0 851779 1477619 0 0 0 0 879184 971326 0 570219 990737 0 0 0 899211 1116396 650903 0 880746 0 1119519 889891 0 734051 0 0 832807 550277 1069863 771719 0 473545 790483 0 540570 0 1813084 0 677518 1048390 0 0 0 0 543633 357373 0 853442 704846 0 0 0 686885 562719 964252 0 484332 0 744786 931777 0 693534 0 0 731979 370927 395846 465722 0 268688 529789 0 142138 0 237252 0 360285 0 0 0 0 0 133760 428258 0 356325 492753 0 0 0 288042 443106 325244 0 491504 0 264752 261001 0 521812 0 0 465610 392013 1130977 470314 0 480377 584132 0 324973 0 813519 0 583553 598764 0 0 0 0 260567 400092 0 441509 503860 0 0 0 803862 683019 470628 0 271368 0 280725 634445 0 566724 -(Gln->pyro-Glu)QYEDRYHEIK MGYG000000271_02101;MGYG000002517_00543;MGYG000000489_01026 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 160015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9893302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8806303 0 0 0 -(Gln->pyro-Glu)QYEDRYHELK MGYG000001637_02230;MGYG000004719_02002;MGYG000000997_00555;MGYG000000271_02101;MGYG000000404_01798;MGYG000002517_00543;MGYG000000489_01026 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 4697409 2962542 2524618 5348300 4904173 4396568 3835778 5871678 3661426 6546082 4531356 5482179 4316468 4973946 6037461 4263135 6322150 0 5740536 4544073 5428430 3001098 0 1925886 5592904 4035247 4811970 0 2505113 5332086 1625173 2281281 2289019 5944194 4475557 4632342 4768136 2011369 317973 190367 187508 206207 268048 294029 205374 256495 0 321811 321720 164879 242404 353678 73010 236014 295546 0 182642 87662 195065 214956 0 188971 258772 205924 192622 0 212509 184760 0 152669 124022 168523 118789 297153 0 247145 1134588 691823 291857 1410367 466445 334473 1332658 1529152 1624689 1747757 1105964 1327469 1876021 1837051 2230183 1448219 645821 0 2277578 2227428 1239267 497323 0 396881 2022225 2365733 2693411 0 1026836 1778883 218003 573573 555770 1353972 1018301 1317859 2584547 759719 13518484 3511045 3466330 12634788 8367114 5028658 7103395 21702823 19096620 9180113 5167916 9109985 4430314 20162213 20527384 5954889 11249408 0 14916442 12778682 9271234 1414218 0 689548 24471196 14465930 15479299 0 4135197 19597006 2970371 4520979 3694644 11150576 15924493 12158384 16496234 2639274 6906059 7599220 14246523 1674563 6315833 9741767 0 6874085 10720150 16538273 11616945 15292629 6500959 15525637 13067880 7416718 13038829 0 10155572 6004500 9705282 6590471 0 7655673 13453349 10205176 12365222 0 2932744 7551158 10470820 3712298 18008078 10759623 0 12224986 18916038 11753038 -(Gln->pyro-Glu)QYEDRYHELKAK MGYG000001637_02230;MGYG000000271_02101;MGYG000000404_01798;MGYG000002517_00543 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYEDRYHILK MGYG000002934_01790;MGYG000000028_00944;MGYG000002523_01027;MGYG000002528_02668 phylum d__Bacteria|p__Firmicutes_A 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.5 186801|Clostridia 0.75 C 1.0 electron transfer flavoprotein 0.5 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 0 329398 224278 0 0 301538 0 0 0 0 0 55877 150928 0 137612 197784 0 0 0 234298 477872 491743 0 225923 251539 0 455466 0 536733 0 0 501640 306318 160513 0 0 0 216855 0 2023183 479972 0 0 693510 0 0 0 0 0 0 298306 0 0 280356 0 0 0 315545 0 591616 0 1297554 90550 0 179838 0 398925 0 0 916798 465155 0 0 0 0 446419 0 7208500 2044536 0 0 2508265 0 0 0 0 0 1695534 1365666 0 1396089 1822508 0 0 0 1154278 1562769 7394866 0 1913497 1417328 0 1391033 0 4426093 0 0 6275728 2974522 2747160 0 0 0 1845243 0 1093966 545902 0 0 392491 0 0 0 0 0 82804 474383 0 171347 206216 0 0 0 359733 233831 460183 0 510902 105839 0 392540 0 2809322 0 0 1173049 602136 0 0 0 0 499802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63879 -(Gln->pyro-Glu)QYEDRYHVVK MGYG000000080_01476;MGYG000002492_00660 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 486699 281131 0 344900 0 0 0 0 0 0 0 155707 0 0 177231 0 316449 0 0 0 0 193354 0 0 0 0 158888 526372 0 0 0 207435 0 0 0 0 137953 0 314641 853831 0 794615 0 0 0 0 0 0 0 227524 0 0 267985 0 1338724 0 0 0 0 759739 0 0 0 0 1108256 357916 0 444719 0 612708 0 0 0 0 844444 0 1165813 5717752 0 1897960 0 0 0 0 0 0 0 2271357 0 0 2267946 0 595218 0 0 0 0 899525 0 0 0 0 1190253 1019042 0 1866193 0 4983354 0 0 0 0 4343446 0 0 264960 0 139933 0 0 0 0 0 0 0 944563 0 0 119259 0 404348 0 0 0 0 0 0 0 0 0 428953 0 0 84507 0 0 0 0 0 0 252182 0 0 218218 0 110651 0 0 0 0 0 0 0 168991 0 0 227785 0 0 0 0 0 0 0 0 0 0 0 194158 2915724 0 0 0 0 0 0 0 0 334025 -(Gln->pyro-Glu)QYEYHILK MGYG000001346_02437 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 2A8EE@1|root,30XG7@2|Bacteria,4NPA9@976|Bacteroidetes,2G2CC@200643|Bacteroidia,4ANGR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1492685 0 0 0 0 1520509 0 0 0 0 1324903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809624 0 0 0 0 813157 0 0 0 0 749801 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYFAETDQTVNKR MGYG000001300_02036;MGYG000000022_00458;MGYG000002224_01508;MGYG000002610_00685;MGYG000000039_00979;MGYG000000589_00366 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 959666 1406259 2093389 1240550 521099 1450351 805278 672877 1153299 1215247 905829 734526 1885342 1609451 1027386 1777944 1761009 1555157 2080053 1169915 0 1246081 795630 1074157 1233372 1098944 847152 1267800 0 658549 1515984 1380628 2322016 1283648 728299 968169 981699 2123465 1666862 2307671 2334906 1521238 1241892 1954885 2108496 735525 2438548 348017 1268836 1883406 1400633 1860382 1487714 1139263 1965463 803356 2651874 2060155 879197 1632728 1081619 1548821 2326943 1569669 1560106 1250401 256177 1509651 1894844 1605294 2433504 1584691 661255 1218534 1837583 1776344 359867 525368 466625 615890 491988 359391 432588 554486 759781 433010 584278 533548 557887 579018 319203 496654 0 1480942 359908 400688 528001 0 1673788 0 354051 0 0 1960234 0 613145 503596 373421 0 648869 0 289020 380169 394505 1234071 1466822 2289470 1254543 2011436 1585485 1959165 856218 1700285 1490555 1786398 2562754 2135884 1707443 1551039 1782592 1612474 1042628 2433733 1249994 1450809 1786703 2067586 1360619 2078336 1726055 1453054 1170387 767670 2183372 1982835 2035184 2401589 2456692 469789 1408306 1872792 2678921 0 280569 377081 0 0 340148 0 324663 301915 0 0 504923 201371 0 0 0 0 1211451 0 0 0 0 1351115 570172 0 235800 0 1763769 0 845372 259481 249887 300785 269921 382038 0 0 180637 -(Gln->pyro-Glu)QYFTKPSIAK MGYG000000053_01407;MGYG000002867_01589;MGYG000003539_01166;MGYG000003467_00952;MGYG000000074_01517;MGYG000001415_00889;MGYG000004241_00281 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,2FUNX@200643|Bacteroidia,22VJS@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS21 family 1.0 rpsU 1.0 - 1.0 - 1.0 ko:K02970 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S21 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 538791 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 898402 0 0 0 0 0 0 556663 0 0 0 0 0 0 0 0 0 0 0 0 0 1396175 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYGHFYLVDTTAMDAAK MGYG000004185_01219;MGYG000002478_00808;MGYG000004797_04277 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,2FSBB@200643|Bacteroidia,22XXG@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 338663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 486714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYGVDTSDIVR MGYG000002517_00849;MGYG000000245_02379 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Kinase, PfkB family 1.0 - 1.0 - 1.0 2.7.1.45 1.0 ko:K00874 1.0 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 1.0 M00061,M00308,M00631 1.0 R01541 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-dehydro-3-deoxygluconokinase. KDG kinase. The enzyme shows no activity with 2-dehydro-3-deoxy-D-galactonate. cf. EC 2.7.1.178. 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D- gluconate + ADP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Metabolic pathways;Carbon metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 162533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326435 0 0 0 0 150133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 823550 0 0 0 0 1054266 0 0 929312 0 0 0 0 0 0 0 0 380996 0 0 0 0 0 0 0 0 0 0 1062411 0 0 0 0 0 0 0 0 0 193786 0 0 0 0 0 0 0 220454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYIEKDAALER MGYG000002247_02283;MGYG000003307_01120;MGYG000002323_03113;MGYG000002476_03390;MGYG000002494_04638;MGYG000000262_01980;MGYG000002515_00455;MGYG000002506_02112;MGYG000000301_00104;MGYG000001315_03285;MGYG000000251_02717;MGYG000001338_00778;MGYG000000133_01006 domain d__Bacteria 1.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WH14@541000|Ruminococcaceae 0.3076923076923077 186801|Clostridia 0.6153846153846154 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 - 0.6153846153846154 - 1.0 ko:K03695,ko:K03696 0.6153846153846154 ko01100,ko04213,map01100,map04213 0.6153846153846154 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N,UVR 0.6153846153846154 - 1.0 - 1.0 - 1.0 GT4 1.0 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways;Longevity regulating pathway - multiple species 0.6153846153846154 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1336634 0 1372498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 979026 0 1424116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYIIDTIAQGGQK MGYG000002492_00882 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,3NHZR@46205|Pseudobutyrivibrio 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366117 0 0 0 0 568337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629730 0 0 0 0 0 0 0 0 0 978806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513039 0 0 0 0 0 0 0 0 0 537456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYIIGTAEKPR MGYG000004769_00454 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4H4PJ@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 768460 813507 0 0 0 1194782 1131424 0 0 1141905 0 0 0 0 0 0 0 455473 0 413537 0 0 0 0 0 0 0 778037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYIQLASGISYK MGYG000000255_01360;MGYG000001338_01563 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2BJ52@1|root,32DE8@2|Bacteria,1UQYJ@1239|Firmicutes,258RQ@186801|Clostridia,3WMD6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Protein of unknown function (DUF2829) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF2829 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766991 0 0 0 0 0 0 -(Gln->pyro-Glu)QYLDHTVYVTYK MGYG000002478_03179 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG3489@1|root,COG3489@2|Bacteria,4NHKU@976|Bacteroidetes,2FTBK@200643|Bacteroidia,4AP8S@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Psort location CytoplasmicMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1771,Peptidase_M75 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 991751 0 0 0 0 1099789 0 0 0 0 942321 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYLEETQSEVR MGYG000002469_00829;MGYG000001490_00724;MGYG000000756_01326;MGYG000003683_00731;MGYG000003452_01613;MGYG000001292_01866;MGYG000003120_01410;MGYG000002395_00735 family d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae 1.0 COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CZ6S@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Ribosomal protein S1 1.0 rpsA 1.0 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYMEVMDQVR MGYG000003697_01173 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AWE5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534491 0 0 0 0 949026 0 0 0 0 504641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYPAEAEELFK MGYG000001345_00428;MGYG000000196_04414 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYQNVEQDTKK MGYG000000243_00374;MGYG000004797_01916 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,2FMD0@200643|Bacteroidia,4AN66@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrB 1.0 - 1.0 1.6.5.8 1.0 ko:K00347 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQR2_RnfD_RnfE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 349067 418009 1074627 456018 688686 445098 0 0 0 0 0 0 1097378 0 0 862010 0 0 0 0 0 415973 0 458234 0 309906 0 0 0 0 600511 0 1119688 0 0 0 446134 960533 0 164577 128988 281023 284138 0 0 0 0 0 0 0 556264 0 0 536110 0 0 0 0 0 267069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587933 542324 996128 207199 526305 372229 0 0 0 0 0 0 0 455801 0 0 357246 0 0 0 0 0 861885 0 0 0 853652 0 0 0 0 280977 0 483760 0 0 0 1015691 0 872815 658445 613724 551435 356243 808893 0 0 0 0 0 0 1022087 0 0 0 0 0 0 0 0 776139 0 535547 0 703076 0 0 0 0 587217 0 383502 0 0 0 942960 788260 704535 845344 545246 0 238292 0 0 0 0 0 0 0 318548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468247 0 221609 0 0 0 0 925893 -(Gln->pyro-Glu)QYQPVN(Deamidated)GNIVFK MGYG000003681_03232;MGYG000001313_03346 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 2DKUK@1|root,30D8W@2|Bacteria,4NNND@976|Bacteroidetes,2G3DK@200643|Bacteroidia,4AQQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 589138 0 0 285079 0 255067 0 0 187814 0 0 0 0 0 0 0 0 0 0 0 310117 0 0 0 0 0 0 0 0 0 0 0 0 722841 909401 1747892 0 0 1157995 543438 0 1572891 0 2266792 0 0 683200 0 0 0 0 0 0 3163107 0 0 0 961397 3000096 0 0 553777 0 693341 0 0 0 0 209568 0 0 971559 548233 1595948 0 0 0 912174 0 1138330 0 2095239 0 0 0 0 1963185 0 0 0 0 1794639 0 0 0 950100 1900866 0 0 1093836 0 786444 0 0 0 0 531542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 279128 0 0 0 0 327136 0 0 0 0 0 0 0 0 0 231802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYQPVNGN(Deamidated)IVFK MGYG000003681_03232;MGYG000001313_03346 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 2DKUK@1|root,30D8W@2|Bacteria,4NNND@976|Bacteroidetes,2G3DK@200643|Bacteroidia,4AQQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 602604 0 0 0 0 423782 0 0 0 0 634618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431588 0 0 0 0 0 0 0 0 0 0 2509377 0 0 0 697982 0 715527 0 0 0 0 843379 0 0 0 0 0 0 0 0 0 946070 825731 0 0 0 0 738727 1169064 0 0 0 0 0 0 0 1633576 0 0 0 0 0 0 0 1363255 0 0 0 0 947583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702639 614392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYQPVNGNIVFK MGYG000003681_03232;MGYG000001313_03346 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 2DKUK@1|root,30D8W@2|Bacteria,4NNND@976|Bacteroidetes,2G3DK@200643|Bacteroidia,4AQQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 405124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353040 0 0 358613 245228 634204 319546 0 889864 0 889286 0 0 1272662 0 1297437 470105 0 0 435124 2007346 403832 0 0 0 1555039 148155 0 418830 0 333387 0 567063 276482 0 602932 0 0 643698 0 0 974227 644639 507583 646714 0 649794 0 804769 0 0 922274 0 1575316 487510 0 0 615118 1193496 925021 0 0 0 1198324 702704 0 985577 0 410881 0 723704 634766 0 682588 0 0 0 0 0 0 267536 0 0 0 0 0 0 0 0 156286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295812 0 0 0 0 0 0 0 0 0 133800 0 0 0 329808 563127 385825 0 0 0 0 0 0 0 0 149081 0 0 0 0 262993 -(Gln->pyro-Glu)QYQVNSAMM(Oxidation)AQTGNPQVK MGYG000002494_02793 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline 1.0 argI 1.0 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.1.3.3,2.1.3.9 1.0 ko:K00611,ko:K09065 1.0 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 1.0 M00029,M00844,M00845 1.0 R01398,R07245 1.0 RC00096 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECS88_1305.ECS88_4841 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ornithine carbamoyltransferase. | N-acetylornithine carbamoyltransferase. OTCase. | N-acetylornithine transcarbamylase. The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively. | Differs from EC 2.1.3.3.-!-This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic pathway of several eubacteria and has no catalytic activity with L-ornithine as substrate. carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate. | carbamoyl phosphate + N(2)-acetyl-L-ornithine = H(+) + N(2)-acetyl-L- citrulline + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYQVNSAMMAQTGNPQVK MGYG000002494_02793 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline 1.0 argI 1.0 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.1.3.3,2.1.3.9 1.0 ko:K00611,ko:K09065 1.0 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 1.0 M00029,M00844,M00845 1.0 R01398,R07245 1.0 RC00096 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECS88_1305.ECS88_4841 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ornithine carbamoyltransferase. | N-acetylornithine carbamoyltransferase. OTCase. | N-acetylornithine transcarbamylase. The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively. | Differs from EC 2.1.3.3.-!-This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic pathway of several eubacteria and has no catalytic activity with L-ornithine as substrate. carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate. | carbamoyl phosphate + N(2)-acetyl-L-ornithine = H(+) + N(2)-acetyl-L- citrulline + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468964 0 0 0 951269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 947153 0 682585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYSDLSSPQKR MGYG000001300_00283;MGYG000003166_01347;MGYG000002641_00066 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3WIHG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit 1.0 rpsL 1.0 - 1.0 - 1.0 ko:K02950 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S12_S23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 909694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1021204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 540022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYSELEEEWKAEK MGYG000002515_00455;MGYG000002506_02112;MGYG000002494_04638 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,3XN3I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 1.0 - 1.0 ko:K03695 1.0 ko04213,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - multiple species 1.0 none 1.0 0 0 0 0 0 465355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 539791 0 496408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1035351 0 575329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYSSQTAYDTDLK MGYG000000074_02389 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG0457@2|Bacteria,4PJ0T@976|Bacteroidetes,2G232@200643|Bacteroidia,22UIZ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_17,TPR_19,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYTGYKDMPR MGYG000000224_00462;MGYG000004748_03256;MGYG000001313_00060;MGYG000000105_02018;MGYG000002561_02189;MGYG000000236_01773;MGYG000002560_00250;MGYG000000243_01957;MGYG000001346_01505 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,2FRZ6@200643|Bacteroidia,22Y1I@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit 1.0 rpsH 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02994 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 1123513 0 0 0 0 910345 0 0 1155139 0 0 0 0 1114201 0 436967 0 0 841029 0 419655 0 0 0 0 0 1028959 0 0 0 1102595 1045296 0 0 0 994763 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327871 0 0 0 0 369931 0 0 1136773 0 0 0 0 0 0 711464 0 0 0 0 468984 0 0 0 0 905151 0 0 0 0 0 279031 0 0 0 0 0 0 0 0 0 0 0 750143 0 0 585946 0 0 0 0 424198 0 627598 0 0 802181 0 0 0 0 0 0 440335 685526 0 0 0 605986 622655 0 0 0 675480 0 0 0 0 0 0 0 0 0 0 1119623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYTHENAQASR MGYG000002171_02172;MGYG000000243_01313;MGYG000002478_03182;MGYG000001783_01513 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG3408@1|root,COG3408@2|Bacteria,4NF09@976|Bacteroidetes,2FMEX@200643|Bacteroidia,4ANWK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 glycogen debranching enzyme, archaeal type 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GDE_C,GDE_N 1.0 - 1.0 GH133 1.0 GH133 1.0 GH133 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 442499 451018 952737 475231 0 646192 0 498984 0 0 389877 0 0 743464 0 1516083 810925 600682 0 0 0 693970 616024 736800 0 521814 0 495459 0 645299 820237 600345 854543 0 0 540729 562184 1028681 348978 228049 446342 366976 0 364844 0 449019 0 0 498871 0 0 417139 0 547462 410941 462871 0 0 0 140323 867938 150515 0 426289 0 316811 0 298705 360708 324039 334787 0 0 0 310834 301852 248060 0 301726 154721 0 0 0 0 0 0 308551 0 0 0 0 436559 0 264545 0 0 0 0 0 251688 0 0 0 0 0 0 212531 0 0 0 0 343065 175811 212731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305136 0 0 419784 0 347767 0 341405 0 0 361065 0 0 0 0 428601 150703 493740 0 0 0 0 526319 113755 0 418385 0 304470 0 293071 293158 363810 198174 0 0 0 420647 362718 -(Gln->pyro-Glu)QYVSNPEEYDFHK MGYG000000074_02412 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 591809 0 0 0 0 0 0 0 0 0 169538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 591766 0 0 800260 835224 629490 0 0 708118 0 0 0 771603 0 629592 542437 633950 0 1057379 1159995 537887 633150 0 467989 560462 849353 0 0 0 1002483 0 0 0 0 0 0 890372 0 -(Gln->pyro-Glu)QYYGETAEILK MGYG000002603_01229;MGYG000003697_00181;MGYG000002293_00655;MGYG000002080_00933 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0149@1|root,COG2259@1|root,COG0149@2|Bacteria,COG2259@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 DoxX,MauE,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 343739 1629667 0 438967 0 0 0 0 0 0 0 0 0 582557 0 0 0 0 0 282036 0 1227532 0 0 0 0 0 0 0 0 1146412 0 0 0 0 838905 0 796474 723151 600088 0 1065003 0 0 0 0 0 0 783197 0 0 600681 0 0 0 0 0 235629 0 475901 0 0 0 0 0 0 0 0 288169 0 0 0 0 223949 0 0 722271 1110775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 818423 0 1131676 0 0 0 0 0 0 0 0 421193 0 0 0 0 1224384 0 1078811 1447553 1138923 0 1276292 0 0 0 0 0 0 1168242 0 0 1342459 0 0 0 0 0 1285616 0 1236200 0 0 0 0 0 0 0 0 1179739 0 0 0 0 1190991 0 256292 273609 377272 0 371789 0 0 0 0 0 0 395647 0 0 325755 0 0 0 0 0 220119 0 488036 0 0 0 0 0 0 0 0 485372 0 0 0 0 511455 -(Gln->pyro-Glu)QYYGETAEILKEK MGYG000002603_01229;MGYG000003697_00181 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0149@1|root,COG2259@1|root,COG0149@2|Bacteria,COG2259@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 DoxX,MauE,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850519 0 0 0 0 727091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Gln->pyro-Glu)QYYGETSATLNKK MGYG000000074_01931;MGYG000000003_00056;MGYG000000437_01534 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia,22UAZ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 577692 0 0 0 628633 0 0 485693 0 0 0 815947 0 0 643599 1019599 0 436811 0 0 406894 0 0 0 436848 640856 0 0 976014 0 601400 0 0 0 0 0 0 529060 189128 848635 549769 525706 481273 0 0 851130 0 0 0 279648 0 0 574463 396184 0 555666 594194 0 437134 0 284910 320868 498752 551392 0 617304 854738 0 654285 574242 0 559262 0 806334 484083 454268 338558 679415 0 379453 452283 0 0 601699 0 0 0 0 0 0 0 518359 0 497563 505993 0 345743 0 377348 285212 561301 0 0 0 653618 0 0 384960 0 536865 0 0 474565 0 0 0 0 0 0 0 0 0 0 0 0 217580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1130870 1283515 1348605 2023564 1867547 1933563 0 0 1418533 0 0 0 1803891 0 0 1499875 1405116 0 2787889 2082504 0 1150608 0 1038123 951165 1413087 941698 0 1556281 2151548 0 1683114 1187537 0 1441104 0 1490787 1474516 -(Glu->pyro-Glu)EFAENEVKPLAQEVDETEEFPVENVKK MGYG000002517_00542 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2845898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu)EGGHTVGSGVVSK MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027;MGYG000003504_00096 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.8333333333333334 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu)EGMGAFLEKR MGYG000002492_00917;MGYG000002670_01219;MGYG000002953_01330;MGYG000002143_01789;MGYG000003185_01503;MGYG000000099_01614;MGYG000001502_02387;MGYG000002926_00641;MGYG000001564_00906;MGYG000003869_00107;MGYG000004271_02656;MGYG000002673_01999;MGYG000002156_02025;MGYG000000271_02750;MGYG000002517_02338;MGYG000000164_00684;MGYG000003694_02682;MGYG000000489_01666;MGYG000003589_00701;MGYG000000356_02284;MGYG000004276_00459;MGYG000004489_00132 domain d__Bacteria 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.3181818181818182 186801|Clostridia 0.9545454545454546 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5454545454545454 crt 0.9545454545454546 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 696715 0 0 0 0 718050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453275 0 0 0 0 412306 0 0 690606 0 0 0 0 0 0 0 0 453549 0 0 0 0 537901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 574356 0 0 0 0 456832 -(Glu->pyro-Glu)EHILLAR MGYG000000042_01421;MGYG000004464_00178;MGYG000001673_01975;MGYG000004704_00398;MGYG000000089_01901;MGYG000004288_00862;MGYG000002619_00483;MGYG000000412_01546;MGYG000002259_00929;MGYG000002926_00232;MGYG000000099_01234;MGYG000004763_01689;MGYG000003681_02037;MGYG000001384_04567;MGYG000003937_01027;MGYG000002707_01740;MGYG000002994_01317;MGYG000001313_00097;MGYG000003266_00392;MGYG000002455_03884;MGYG000000348_00283;MGYG000001776_00769;MGYG000000044_01721;MGYG000001672_00396;MGYG000002059_00460;MGYG000002685_01157;MGYG000002557_00102;MGYG000000196_03974;MGYG000001008_02651;MGYG000001661_02666;MGYG000001300_00280;MGYG000004769_00437;MGYG000002084_01252;MGYG000000433_00368;MGYG000003022_00748;MGYG000002040_01212;MGYG000002098_01616;MGYG000003266_00955;MGYG000000098_02017;MGYG000001757_01274;MGYG000001299_01777;MGYG000002224_01123;MGYG000002438_02321;MGYG000000163_00957;MGYG000004285_00597;MGYG000001346_01533;MGYG000003073_01160;MGYG000001616_00520;MGYG000003921_01124;MGYG000001238_02207;MGYG000002996_00986;MGYG000002052_00232;MGYG000002418_00753;MGYG000002448_02351;MGYG000000223_03134;MGYG000003352_00730;MGYG000001319_01764;MGYG000004757_00594;MGYG000001365_00649;MGYG000002695_01057;MGYG000000138_00665;MGYG000004769_00412;MGYG000001630_01142;MGYG000002673_02521;MGYG000003022_00735;MGYG000004717_00227;MGYG000000365_00508;MGYG000004276_00122;MGYG000001925_01419;MGYG000000273_00431;MGYG000000867_00556;MGYG000004788_02115;MGYG000000291_00377;MGYG000003202_00129;MGYG000002993_01302;MGYG000000357_02040;MGYG000002953_03321;MGYG000003546_00955;MGYG000000375_01434;MGYG000000022_02283;MGYG000002901_00528;MGYG000003446_00658;MGYG000003899_01642;MGYG000003891_00382;MGYG000002925_00238;MGYG000003428_00555;MGYG000000490_01981;MGYG000003686_02367;MGYG000001356_01661;MGYG000001655_02933;MGYG000003977_00001;MGYG000003166_01350;MGYG000003170_00035;MGYG000002905_00001;MGYG000002972_00178;MGYG000002098_00731;MGYG000002702_01978;MGYG000002912_01340;MGYG000003424_00456;MGYG000001789_00154;MGYG000001567_01738;MGYG000000182_00585;MGYG000003441_00074;MGYG000000236_01807;MGYG000003701_03123;MGYG000000084_02000;MGYG000002291_02272;MGYG000004642_00846;MGYG000000187_02029;MGYG000002641_00069;MGYG000001500_01929;MGYG000003170_00048;MGYG000000445_01370;MGYG000002272_01482;MGYG000004221_01651;MGYG000000243_01988;MGYG000001780_03476;MGYG000001665_01696;MGYG000003504_00096;MGYG000001421_00009;MGYG000001646_01118;MGYG000004047_00605 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.1721311475409836 186801|Clostridia 0.45081967213114754 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9590163934426229 - 1.0 ko:K02358 0.9836065573770492 - 0.9836065573770492 - 0.9836065573770492 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9836065573770492 - 0.9836065573770492 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9836065573770492 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1112560 0 0 0 0 0 0 0 0 1108220 0 1207621 0 0 0 0 0 918570 0 0 0 0 1195263 0 0 0 0 1405735 0 0 407963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032510 0 0 0 -(Glu->pyro-Glu)EHILLSR MGYG000000080_02058;MGYG000000245_03248;MGYG000001688_04229;MGYG000001654_02237;MGYG000004718_00646;MGYG000004735_00884;MGYG000000280_01200;MGYG000004565_01266;MGYG000001714_01291;MGYG000001760_00949;MGYG000000198_01165;MGYG000004893_00932;MGYG000000392_00966;MGYG000003324_00542;MGYG000002563_00522;MGYG000001507_06245;MGYG000000133_02991;MGYG000000919_01815;MGYG000004879_01608;MGYG000001234_01151;MGYG000001623_00993;MGYG000000466_00679;MGYG000000446_00437;MGYG000002202_00030;MGYG000003208_02857;MGYG000002563_00509;MGYG000003895_00135;MGYG000001619_01314;MGYG000000216_02406;MGYG000002517_00205;MGYG000000034_01346;MGYG000000123_01153;MGYG000004296_01668;MGYG000000277_00173;MGYG000004508_00787;MGYG000001469_02077;MGYG000001431_01181;MGYG000001809_00576;MGYG000001652_01300;MGYG000000127_03982;MGYG000000258_00266;MGYG000002670_00364;MGYG000004502_00031;MGYG000004600_00789;MGYG000001635_01137;MGYG000000139_00697;MGYG000001611_00087;MGYG000000255_02009;MGYG000000404_00531;MGYG000000164_01096;MGYG000000018_00453;MGYG000002234_01026;MGYG000000032_01232;MGYG000001777_01732;MGYG000002105_00002;MGYG000000347_00343;MGYG000000532_02409;MGYG000002136_02858;MGYG000003146_01522;MGYG000002286_02469;MGYG000000262_00030;MGYG000001412_04734;MGYG000002772_01895;MGYG000002492_00344;MGYG000003753_00317;MGYG000001615_01716;MGYG000002854_00111;MGYG000001487_02232;MGYG000000143_00646;MGYG000000016_02519;MGYG000002279_01932;MGYG000000201_03875;MGYG000002485_02622;MGYG000004547_01366;MGYG000003063_00662;MGYG000004893_01944;MGYG000000271_03365;MGYG000000185_02848;MGYG000000230_00429;MGYG000001315_01207;MGYG000001602_02247;MGYG000001508_00032;MGYG000001464_00103;MGYG000001558_01002;MGYG000001400_03001;MGYG000001405_04470;MGYG000001310_01963;MGYG000003273_00234;MGYG000000140_01590;MGYG000001404_04883;MGYG000000323_00619;MGYG000001065_02730;MGYG000002528_01098;MGYG000004302_00459;MGYG000004680_02443;MGYG000002609_01147;MGYG000001436_02249;MGYG000000263_00836;MGYG000000157_01091;MGYG000004789_00520;MGYG000000179_00920;MGYG000000134_02651;MGYG000002839_00878;MGYG000000217_01428;MGYG000000173_00405;MGYG000000177_01044;MGYG000001485_02164;MGYG000002290_01325;MGYG000001531_00906;MGYG000002220_00457;MGYG000002195_01684;MGYG000001607_01045;MGYG000000226_00644;MGYG000001141_02439;MGYG000000024_03409;MGYG000003425_03741;MGYG000000251_00064;MGYG000002444_02629;MGYG000000233_00807;MGYG000000142_00171;MGYG000000121_02189;MGYG000001528_00736;MGYG000004087_00551;MGYG000001439_02427;MGYG000000242_00282;MGYG000004216_00603;MGYG000002417_01244;MGYG000002126_00299;MGYG000000335_01138;MGYG000002854_00124;MGYG000001698_04050;MGYG000004558_00415;MGYG000003074_01359;MGYG000000037_01050;MGYG000002837_02416;MGYG000002997_01472;MGYG000000193_02083;MGYG000002212_00196;MGYG000000249_00026;MGYG000003236_02455;MGYG000000121_03149;MGYG000004799_01385;MGYG000000501_01307;MGYG000004630_01824;MGYG000000045_02616;MGYG000001814_01592;MGYG000003656_01823;MGYG000001432_01745;MGYG000003486_01055;MGYG000001617_01406;MGYG000002596_02296;MGYG000001712_00119;MGYG000003620_01283;MGYG000001007_01315;MGYG000003486_01459;MGYG000001732_00030;MGYG000000206_00901;MGYG000004733_01211 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.13924050632911392 186801|Clostridia 0.740506329113924 J 0.9873417721518988 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9810126582278481 tuf 0.9873417721518988 - 0.8164556962025317 - 0.9936708860759493 ko:K02358 0.930379746835443 - 0.9367088607594937 - 0.9430379746835443 - 0.9936708860759493 - 0.9936708860759493 ko00000,ko03012,ko03029,ko04147 0.930379746835443 - 0.9430379746835443 - 0.9936708860759493 - 0.930379746835443 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 0.9873417721518988 - 0.9936708860759493 - 0.9936708860759493 - 0.9936708860759493 - 0.9936708860759493 - - - - 0.9936708860759493 0.9936708860759493 0.9936708860759493 0.9936708860759493 0.9367088607594937 none 1.0 511134 0 237422 244930 876653 0 0 0 0 818192 0 620917 0 0 909461 0 524579 720929 0 0 0 0 128074 0 0 288067 252407 387637 220476 0 0 550359 0 575141 325995 0 214993 575007 331697 0 274525 516586 450839 0 0 0 0 218212 0 340879 0 0 270730 0 165876 720889 0 0 0 0 495383 0 0 201435 394738 764906 370845 0 0 377758 0 549022 452082 0 343925 456359 1114254 0 973728 992215 220250 0 0 0 0 1069351 0 477635 0 0 1097886 0 849945 0 0 0 0 0 695582 0 0 842335 1162213 1158843 984717 0 0 1309867 1011204 1294390 1121310 0 823647 793938 519724 0 433478 835790 527388 0 0 0 0 545656 0 414895 0 0 627604 0 595790 247198 0 0 0 0 0 0 0 717548 836405 210443 650149 0 0 756970 589341 526907 745637 0 732970 508831 1009305 0 1605992 1358655 418807 0 0 0 0 1483800 0 1388992 0 0 1413985 0 1255282 275154 0 0 0 0 529918 0 0 966106 1173193 438157 1924351 0 0 1076145 1957743 1371534 1291494 0 1297436 1149790 -(Glu->pyro-Glu)EHLLLAR MGYG000000408_01653;MGYG000004732_02398;MGYG000000089_01901;MGYG000000362_00956;MGYG000003547_00975;MGYG000002259_00929;MGYG000001754_00089;MGYG000004694_00667;MGYG000003155_00314;MGYG000004763_01689;MGYG000004685_00908;MGYG000001384_04567;MGYG000003937_01027;MGYG000003992_01709;MGYG000002455_03884;MGYG000000348_00283;MGYG000001672_00396;MGYG000002059_00460;MGYG000001008_02651;MGYG000000196_03974;MGYG000004573_00004;MGYG000001434_01407;MGYG000001661_02666;MGYG000001541_00185;MGYG000001300_00280;MGYG000003851_00676;MGYG000004769_00437;MGYG000002084_01252;MGYG000003869_01538;MGYG000002578_00911;MGYG000000433_00368;MGYG000000349_00457;MGYG000002040_01212;MGYG000000054_03933;MGYG000004528_00894;MGYG000002794_01318;MGYG000001606_01669;MGYG000000202_03457;MGYG000003442_01057;MGYG000004474_01617;MGYG000003868_01133;MGYG000001359_01254;MGYG000002224_01123;MGYG000004201_01254;MGYG000000036_01380;MGYG000003410_00864;MGYG000003073_01160;MGYG000001616_00520;MGYG000002052_00232;MGYG000002418_00753;MGYG000000369_00927;MGYG000000223_03134;MGYG000003352_00730;MGYG000001334_00218;MGYG000002447_00587;MGYG000004757_00594;MGYG000001365_00649;MGYG000002116_00788;MGYG000002695_01057;MGYG000001756_00183;MGYG000003819_01356;MGYG000004769_00412;MGYG000000395_01440;MGYG000001524_01606;MGYG000001193_00787;MGYG000004724_00878;MGYG000000802_00776;MGYG000000372_00001;MGYG000000273_00431;MGYG000000291_00377;MGYG000003202_00129;MGYG000002944_02285;MGYG000002281_02290;MGYG000002447_00574;MGYG000002993_01302;MGYG000002953_03321;MGYG000003546_00955;MGYG000000022_02283;MGYG000002470_01245;MGYG000000375_01434;MGYG000002901_00528;MGYG000000090_01714;MGYG000001737_01514;MGYG000003891_00382;MGYG000003428_00555;MGYG000000490_01981;MGYG000003686_02367;MGYG000001784_02227;MGYG000001749_02490;MGYG000002980_01277;MGYG000001779_00600;MGYG000001356_01661;MGYG000000488_00776;MGYG000000479_00469;MGYG000002930_00867;MGYG000004526_00639;MGYG000003166_01350;MGYG000003868_01166;MGYG000001677_00114;MGYG000003170_00035;MGYG000002905_00001;MGYG000001590_00854;MGYG000002098_00731;MGYG000002912_01340;MGYG000002702_01978;MGYG000003424_00456;MGYG000000182_00585;MGYG000003441_00074;MGYG000002143_01659;MGYG000000084_02000;MGYG000002291_02272;MGYG000004642_00846;MGYG000004300_00119;MGYG000001559_00042;MGYG000000945_00137;MGYG000000187_02029;MGYG000003185_01053;MGYG000000420_01950;MGYG000003170_00048;MGYG000000445_01370;MGYG000002272_01482;MGYG000004221_01651;MGYG000001444_01618;MGYG000003516_01606;MGYG000000243_01988;MGYG000001780_03476;MGYG000004657_01190;MGYG000002540_03367;MGYG000000254_02569;MGYG000001646_01118;MGYG000003660_00194;MGYG000002042_00774;MGYG000002970_01555;MGYG000003013_00349;MGYG000003484_00308;MGYG000000117_01463;MGYG000002659_00459;MGYG000000042_01421;MGYG000003096_01037;MGYG000002106_00224;MGYG000004464_00178;MGYG000004704_00398;MGYG000001673_01975;MGYG000000385_01364;MGYG000004288_00862;MGYG000002619_00483;MGYG000000412_01546;MGYG000000930_01271;MGYG000002926_00232;MGYG000002578_00898;MGYG000000099_01234;MGYG000003460_01161;MGYG000003681_02037;MGYG000001739_00819;MGYG000002707_01740;MGYG000003185_01074;MGYG000001444_01634;MGYG000002994_01317;MGYG000002165_00803;MGYG000001313_00097;MGYG000002654_00465;MGYG000003266_00392;MGYG000004119_01204;MGYG000004482_01535;MGYG000001576_02230;MGYG000001824_01594;MGYG000003628_01000;MGYG000001563_01273;MGYG000001776_00769;MGYG000000044_01721;MGYG000003549_00407;MGYG000002685_01157;MGYG000004800_00190;MGYG000002762_01733;MGYG000003022_00748;MGYG000001502_01278;MGYG000002098_01616;MGYG000003266_00955;MGYG000004826_01022;MGYG000000098_02017;MGYG000003274_01474;MGYG000001757_01274;MGYG000001299_01777;MGYG000002950.1_00050;MGYG000002438_02321;MGYG000002556_01332;MGYG000000163_00957;MGYG000000267_01379;MGYG000001346_01533;MGYG000004285_00597;MGYG000000333_00136;MGYG000004196_01067;MGYG000003497_00215;MGYG000002768_00022;MGYG000002057_01066;MGYG000003921_01124;MGYG000001238_02207;MGYG000002996_00986;MGYG000002448_02351;MGYG000004475_00887;MGYG000000168_03211;MGYG000001319_01764;MGYG000001881_00748;MGYG000004847_01222;MGYG000000138_00665;MGYG000001630_01142;MGYG000002673_02521;MGYG000003022_00735;MGYG000003528_02124;MGYG000001516_01186;MGYG000004717_00227;MGYG000004726_01622;MGYG000004276_00122;MGYG000000365_00508;MGYG000001925_01419;MGYG000004788_02115;MGYG000000266_00259;MGYG000001503_00139;MGYG000000449_00614;MGYG000000120_01190;MGYG000003446_00658;MGYG000001552_00984;MGYG000003899_01642;MGYG000000013_02251;MGYG000003583_01411;MGYG000002925_00238;MGYG000001655_02933;MGYG000001991_00383;MGYG000003977_00001;MGYG000003872_01017;MGYG000002972_00178;MGYG000001567_01738;MGYG000001789_00154;MGYG000000236_01807;MGYG000003701_03123;MGYG000003389_01825;MGYG000004694_00680;MGYG000001559_01093;MGYG000002641_00069;MGYG000000733_01034;MGYG000002114_00077;MGYG000001500_01929;MGYG000000370_00784;MGYG000002006_00835;MGYG000000622_01283;MGYG000002720_00092;MGYG000004746_00230;MGYG000001665_01696;MGYG000003504_00096;MGYG000001421_00009;MGYG000002848_00884;MGYG000003001_00359;MGYG000004047_00605;MGYG000000673_00997 life d__Bacteria 0.9961 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.16141732283464566 186801|Clostridia 0.484251968503937 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.952755905511811 - 1.0 ko:K02358 0.984251968503937 - 0.984251968503937 - 0.984251968503937 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.984251968503937 - 0.984251968503937 - 1.0 - 0.9881889763779528 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.984251968503937 none 1.0 982443 0 1123225 0 0 1096118 0 0 763854 0 0 220569 1847175 0 928460 1637824 0 1527825 0 0 0 1050793 1102718 1038990 0 1025156 1011133 1159515 0 0 0 0 1396539 0 0 0 996447 1064930 967219 0 0 0 0 991837 0 0 1301465 0 0 0 1343930 0 1073465 1167351 0 1062085 0 0 0 744806 1377658 883909 0 1227051 1013610 1189745 0 0 0 0 950645 0 0 0 1084015 1223856 876721 0 935552 0 0 906279 0 0 910020 0 0 497373 1044088 0 692984 836317 0 1270124 0 0 0 697565 1362012 952931 0 802240 832730 1468822 0 0 0 0 860189 0 0 0 886354 782330 451632 0 288699 0 0 435629 0 0 420835 0 0 646882 877832 0 401344 650909 0 414734 0 0 0 446348 450604 379379 0 478276 394246 179433 0 0 0 0 489596 0 0 0 495553 445128 677093 0 602321 0 0 1040811 0 0 895089 0 0 1216063 1269887 0 729062 1122729 0 1806153 0 0 0 566274 1794548 1365404 0 817463 624701 1570308 0 0 0 0 442280 0 0 0 702505 995462 -(Glu->pyro-Glu)ELNLDAIHDTVHEMAKDEAR MGYG000000278_01143;MGYG000004866_00011;MGYG000000084_01252;MGYG000001157_01204;MGYG000001627_00301;MGYG000003921_01704 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3WGYN@541000|Ruminococcaceae 0.8333333333333334 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.8333333333333334 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 847048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl)EAGLYKNER MGYG000000243_01844 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FN0E@200643|Bacteroidia,22WXW@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA 1.0 kbl 1.0 - 1.0 2.3.1.29 1.0 ko:K00639 1.0 ko00260,map00260 1.0 - 1.0 R00371 1.0 RC00004,RC00394 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine C-acetyltransferase. 2-amino-3-ketobutyrate coenzyme A ligase. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism 1.0 none 1.0 0 0 0 0 0 461488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459267 0 421665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 266678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 130026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl)EGEELAALNPHIVVK MGYG000002549_02719;MGYG000001378_02110;MGYG000000013_01251;MGYG000002470_00140;MGYG000003351_02105;MGYG000000243_01624;MGYG000001661_03030;MGYG000000105_01128;MGYG000001346_02599;MGYG000004899_00244;MGYG000002478_03826;MGYG000004823_01716;MGYG000003681_01529;MGYG000000224_01690;MGYG000004876_00604;MGYG000000174_01155;MGYG000004763_01631 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,2FNM3@200643|Bacteroidia,4AM98@815|Bacteroidaceae 0.9411764705882353 976|Bacteroidetes 1.0 F 1.0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616,ko:K08314 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CBS,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl)EGGLVTAGNASGINDGAAAIVVMSEEK MGYG000000997_00552;MGYG000004271_00231;MGYG000002278_01891;MGYG000000245_02019;MGYG000000280_01473;MGYG000000271_02104;MGYG000001637_02269;MGYG000002517_00540;MGYG000003694_00877;MGYG000000153_01463;MGYG000000389_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.9090909090909091 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl)ENGIIHGTASLFR MGYG000002478_01935 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 83774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416230 0 0 0 0 555655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 373134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))EAFPGDVFYLHSR MGYG000002323_04217;MGYG000001785_00791;MGYG000002532_03724;MGYG000000093_05346;MGYG000002366_00008;MGYG000002515_03905;MGYG000002421_01630;MGYG000002385_03599;MGYG000002494_02406;MGYG000002506_03404 domain d__Bacteria 1.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,3XP3D@561|Escherichia 0.7 1236|Gammaproteobacteria 0.7 F 0.7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 0.8 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 iSbBS512_1146.SbBS512_E4187 0.7 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 0.8 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1072617 1162989 0 696910 0 0 0 0 0 0 381495 0 0 0 0 0 0 848025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1027280 0 115924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 52576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))EAGMNDVVLVGGR MGYG000002492_01331;MGYG000000280_02128;MGYG000000356_00314 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 0.3333333333333333 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))EGASKAEAEDIKAK MGYG000002528_01112;MGYG000000028_00269 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,36IQP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))EGLDVLEYFISAHGAR MGYG000002528_01102;MGYG000000198_01126;MGYG000000179_00949;MGYG000001714_01233;MGYG000002445_01330;MGYG000001683_01329;MGYG000000262_00026 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,21Y1Y@1506553|Lachnoclostridium 0.42857142857142855 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))EGLNPIKEEMAK MGYG000000184_01931;MGYG000000213_04019;MGYG000001338_00282 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3XYME@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 1.1.1.38 1.0 ko:K00027 1.0 ko00620,ko01200,ko02020,map00620,map01200,map02020 1.0 - 1.0 R00214 1.0 RC00105 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 malate dehydrogenase (oxaloacetate-decarboxylating). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392638 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 536690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238794 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))EIAEATDFVDGR MGYG000001292_01122;MGYG000003683_00464;MGYG000000756_00775;MGYG000001490_00981;MGYG000002469_01093;MGYG000002396_01111 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))EITAEDTADMLK MGYG000002494_01063 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1282@1|root,2QQ0A@2759|Eukaryota,38CB0@33154|Opisthokonta,3BDQK@33208|Metazoa,3CWZ6@33213|Bilateria,41XXS@6656|Arthropoda,3SFQ1@50557|Insecta,450JW@7147|Diptera 1.0 33208|Metazoa 1.0 C 1.0 NAD(P) transhydrogenase beta subunit 1.0 - 1.0 - 1.0 1.6.1.2 1.0 ko:K00323 1.0 ko00760,ko01100,map00760,map01100 1.0 - 1.0 R00112 1.0 RC00001 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 AlaDh_PNT_C,AlaDh_PNT_N,PNTB,PNTB_4TM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 proton-translocating NAD(P)(+) transhydrogenase. - The enzyme is a membrane bound proton-translocating pyridine nucleotide transhydrogenase that couples the reversible reduction of NADP by NADH to an inward proton translocation across the membrane.-!-In the bacterium Escherichia coli the enzyme provides a major source of cytosolic NADPH.-!-Detoxification of reactive oxygen species in mitochondria by glutathione peroxidases depends on NADPH produced by this enzyme.-!-Formerly EC 1.6.1.2 and EC 1.6.1.5. H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+). 1.0 1.0 1.0 1.0 Metabolic pathways;Nicotinate and nicotinamide metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1474830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1717325 0 0 3105056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3186122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429611 0 0 0 0 319454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1877928 0 0 0 0 2856959 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))EMFIANTTGTSSTDRIEGMIK MGYG000001315_00856 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0416@1|root,COG0416@2|Bacteria,1TPY8@1239|Firmicutes,248BX@186801|Clostridia,27K0U@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Fatty acid synthesis protein 1.0 grdD 1.0 - 1.0 1.21.4.2,1.21.4.3,1.21.4.4 1.0 ko:K21576 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 FA_synthesis 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine reductase. | sarcosine reductase. | betaine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. | The reaction is observed only in the direction of sarcosine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.4. | The reaction is observed only in the direction of betaine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.3. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. | [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine. | [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125351 0 0 0 0 0 0 0 0 0 0 0 0 370785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603442 0 0 0 0 0 0 0 0 0 0 483139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))EQVEMIEER MGYG000002506_02717 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3XNX9@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 K 1.0 transcriptional regulator 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 2157545 0 0 0 0 0 0 1667379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3124225 0 0 0 0 0 0 898334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2174949 0 0 0 0 0 0 395563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 615237 0 0 0 0 0 0 2907047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))ERPIDENLGSYEDVDEAVK MGYG000001338_02427;MGYG000000184_00682;MGYG000000200_00069 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1296747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))ETANMISFMADVIGIR MGYG000000262_01807;MGYG000001531_01879;MGYG000004799_00956;MGYG000000249_00985;MGYG000000268_02435;MGYG000000179_04170;MGYG000001714_00587;MGYG000001065_01053;MGYG000001619_01751;MGYG000000198_04461;MGYG000001496_02433 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0078@1|root,COG0078@2|Bacteria,1TNY4@1239|Firmicutes,249P4@186801|Clostridia,26870@186813|unclassified Clostridiales 0.36363636363636365 186801|Clostridia 1.0 E 1.0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 0.7272727272727273 ygeW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))ETVPVFHVGDTVK MGYG000000179_01851 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,2206I@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 - 1.0 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glu->pyro-Glu+Methyl_2H(2)13C(1))EVNELATILKEEYGIEPAAAAVAVAAGPAAGAAAAEEK MGYG000004797_04276;MGYG000002478_00807 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5716024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glucuronyl)VVQHNITAMNANR MGYG000000562_01318;MGYG000004271_01770;MGYG000000271_01499;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.75 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 3273205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Glucuronyl)VVQHNLTAMNANR MGYG000004271_01770;MGYG000000153_01160;MGYG000000271_01499;MGYG000000404_00502;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 1519017 0 0 0 0 0 0 0 0 3089803 0 0 0 0 0 2656109 1088197 0 950298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368941 0 0 0 0 0 316225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1484673 0 0 0 0 0 2751080 1475311 0 718686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352680 0 0 0 0 0 765527 0 0 397445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Guanidinyl)AAFEEAEHAAK MGYG000003509_00509;MGYG000000177_00118;MGYG000002026_00456;MGYG000003891_00390;MGYG000004769_01404;MGYG000000198_03730;MGYG000000172_04155;MGYG000004087_01663;MGYG000001434_00926;MGYG000000198_03710;MGYG000004087_01662;MGYG000001564_01103;MGYG000001311_01511;MGYG000001493_02801;MGYG000001493_02800;MGYG000003422_00075;MGYG000004713_00792 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,21YU6@1506553|Lachnoclostridium 0.5294117647058824 186801|Clostridia 0.8823529411764706 C 1.0 Rubrerythrin 0.6470588235294118 rbr3A 0.9411764705882353 - 0.9411764705882353 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.8823529411764706 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Guanidinyl)AINSGVTDKYK MGYG000003266_00038 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900762015|m__MGYG000003266 1.0 COG3444@1|root,COG3444@2|Bacteria,2GR9K@201174|Actinobacteria,4CVTK@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 PTS system sorbose subfamily IIB component 1.0 - 1.0 - 1.0 - 1.0 ko:K19507 1.0 ko02060,map02060 1.0 M00764 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.6.1.19 1.0 - 1.0 - 1.0 PTSIIB_sorb 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Guanidinyl)EGLATGLGDEGGFAPK MGYG000003683_00763;MGYG000003452_01522 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CYT3@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1921627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Guanidinyl)EGVANKDKPLVWFNR MGYG000004735_00164 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 879063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1555970 0 0 0 0 0 0 0 0 0 -(Guanidinyl)IPEPEHENDKPFLMPVEDVFTITGR MGYG000002052_00232 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum|s__|m__MGYG000002052 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 474651048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Guanidinyl)NISIAEKGHEER MGYG000002455_00941;MGYG000002470_04315;MGYG000002549_03230;MGYG000001378_00441;MGYG000000054_04429;MGYG000000029_03153;MGYG000000098_02688;MGYG000001337_00622;MGYG000000236_03467;MGYG000004464_01206;MGYG000000196_03295 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1592@1|root,COG1592@2|Bacteria,4NH0J@976|Bacteroidetes,2FNC9@200643|Bacteroidia,4AKRD@815|Bacteroidaceae 0.9090909090909091 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 0.9090909090909091 rbr 1.0 GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331405 0 0 0 0 0 0 0 353989 0 275891 0 0 0 0 271090 0 0 0 0 349642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Guanidinyl)SAAELNEELVAAKK MGYG000000038_01584;MGYG000000213_00206;MGYG000000184_01180;MGYG000002945_02576;MGYG000002845_00986;MGYG000001607_01093;MGYG000004733_00976;MGYG000000206_01042;MGYG000001496_03128;MGYG000001748_00602;MGYG000001710_03003;MGYG000001338_02799;MGYG000000200_01105;MGYG000002966_02567;MGYG000000002_00874;MGYG000001698_02694;MGYG000000118_00226;MGYG000000133_00053;MGYG000000301_00168;MGYG000002279_01064 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3Y0MW@572511|Blautia 0.45 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uL29 family 1.0 rpmC 1.0 - 1.0 - 1.0 ko:K02904 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L29 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1259727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Guanidinyl)SNVIVKDNESLDSALRR MGYG000001065_00121;MGYG000001954_00183;MGYG000001531_02509;MGYG000000087_00069;MGYG000000278_03375;MGYG000001606_01557;MGYG000000255_00059;MGYG000002417_00179;MGYG000002445_00245 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 0.7777777777777778 203691|Spirochaetes 0.7777777777777778 L 0.7777777777777778 PFAM Integrase core domain 0.7777777777777778 - 0.7777777777777778 - 1.0 - 1.0 ko:K07497 0.7777777777777778 - 0.7777777777777778 - 0.7777777777777778 - 1.0 - 1.0 ko00000 0.7777777777777778 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.7777777777777778 none 1.0 0 0 0 470787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2054824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633060 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1154616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Hex)AFAPDVIIALGGGSAMDAGK MGYG000003504_01226 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-314|g__CAG-1435|s__CAG-1435 sp003537755|m__MGYG000003504 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117234005 0 0 0 0 0 0 0 0 0 0 0 -(Hex)LSSGYKINR MGYG000002580_01396;MGYG000000136_01850;MGYG000000076_00961;MGYG000004039_00624;MGYG000004317_00523;MGYG000003694_02093;MGYG000000099_02202;MGYG000004317_00093;MGYG000002552_01183;MGYG000000489_01309;MGYG000001617_02963;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000000099_03212;MGYG000000205_00843;MGYG000000154_02141;MGYG000003422_01457;MGYG000002517_00135;MGYG000000417_00080;MGYG000000217_01135;MGYG000001141_01878;MGYG000000356_01643;MGYG000000398_01070;MGYG000003422_01458;MGYG000000187_02828;MGYG000001065_00070;MGYG000003215_01405;MGYG000002247_02078;MGYG000000562_01318;MGYG000000562_01835;MGYG000001637_00814;MGYG000000245_00974;MGYG000003694_00680;MGYG000000271_01499;MGYG000001186_01647;MGYG000004414_00337;MGYG000004831_00621;MGYG000000217_00038;MGYG000003694_03279;MGYG000001500_00161 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae 0.3488372093023256 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9534883720930233 - 0.8372093023255814 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.8837209302325582 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ICPL_13C(6))ADIIMILINDEK MGYG000000301_00839;MGYG000004735_00452;MGYG000000201_04066;MGYG000004087_02660;MGYG000001496_01234;MGYG000000271_00298;MGYG000002517_01587 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 0.42857142857142855 186801|Clostridia 1.0 EH 0.5714285714285714 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2718641 0 0 0 0 0 0 -(ICPL_13C(6))DTDKPFVMPVEDVFSITGR MGYG000000216_02406;MGYG000000171_02844;MGYG000000201_03875;MGYG000001338_03373;MGYG000000142_00171;MGYG000000212_03313;MGYG000004733_01211 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ICPL_13C(6))GLEARLYMWEGDYAK MGYG000003697_00737;MGYG000002080_01611 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG3193@1|root,COG3193@2|Bacteria,4NKF2@976|Bacteroidetes,2G0TY@200643|Bacteroidia,4AVF2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284379 0 337013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1382560 0 2482100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 202869 0 338610 0 0 0 0 0 0 0 0 0 0 0 -(ICPL_13C(6)2H(4))GLVTTIAWGLDGK MGYG000001315_01111;MGYG000004733_00600;MGYG000002059_01430;MGYG000000489_00188;MGYG000000038_01493;MGYG000002946_02679;MGYG000001698_01656;MGYG000000164_01754;MGYG000002274_01022;MGYG000000271_02110;MGYG000001338_01881;MGYG000002517_00259;MGYG000002186_01069;MGYG000000205_00108;MGYG000000187_00247;MGYG000001496_03285;MGYG000000489_01562;MGYG000000245_01078;MGYG000000249_01696;MGYG000002756_00504;MGYG000000389_02030;MGYG000000184_02616;MGYG000004087_02483;MGYG000001617_02316;MGYG000002517_00523;MGYG000000179_02171;MGYG000002105_01106;MGYG000000198_04024 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 0.2857142857142857 186801|Clostridia 1.0 F 0.5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44918860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ICPL_13C(6)2H(4))ISKWNATSLEAR MGYG000000184_00682 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A luti|m__MGYG000000184 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 929396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1030169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114136 0 0 0 0 0 0 0 0 -(ICPL_13C(6)2H(4))LAAADVNPDTR MGYG000000193_02120 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__KLE1615|s__KLE1615 sp900066985|m__MGYG000000193 1.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 - 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ICPL_13C(6)2H(4))LQSATLDDLGTAHQVR MGYG000004804_00243 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900759415|m__MGYG000004804 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4H29X@909932|Negativicutes 1.0 909932|Negativicutes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 - 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ICPL_13C(6)2H(4))NLSNSSADVVDNIEK MGYG000002478_04317 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,2FMV2@200643|Bacteroidia,4AMM1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family 1.0 galE 1.0 - 1.0 5.1.3.2 1.0 ko:K01784 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00361,M00362,M00632 1.0 R00291,R02984 1.0 RC00289 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 UDP-glucose 4-epimerase. uridine diphospho-galactose-4-epimerase. Also acts on UDP-2-deoxyglucose. UDP-alpha-D-glucose = UDP-alpha-D-galactose. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 779816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 735902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ICPL_13C(6)2H(4))VEHFGRLGGIVFTPDEVLNALK MGYG000001489_03267;MGYG000002438_03197 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0674@1|root,COG0674@2|Bacteria,4NGYK@976|Bacteroidetes,2FM6R@200643|Bacteroidia,22WCE@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA 1.0 vorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00174 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFOR_II,POR_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14406931 0 0 0 0 0 0 0 0 -(ICPL_2H(4))ADIIMILINDEK MGYG000000301_00839;MGYG000004735_00452;MGYG000000201_04066;MGYG000004087_02660;MGYG000001496_01234;MGYG000000271_00298;MGYG000002517_01587 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 0.42857142857142855 186801|Clostridia 1.0 EH 0.5714285714285714 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3141999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 936250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ISD_z+2_ion)EGALSETHSILQR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 303582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297724 0 178246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9428955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ISD_z+2_ion)EYQYFPFEPK MGYG000001313_02680 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,2FNGC@200643|Bacteroidia,4AKIZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Belongs to the GHMP kinase family. GalK subfamily 1.0 galK 1.0 - 1.0 2.7.1.6 1.0 ko:K00849 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00554,M00632 1.0 R01092 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 galactokinase. - Part of the Leloir pathway for galactose metabolism.-!-The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine. alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+). 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1970938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ISD_z+2_ion)GINPNAFDGR MGYG000000099_02389 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,268U3@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits 1.0 rplE 1.0 - 1.0 - 1.0 ko:K02931 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L5,Ribosomal_L5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ISD_z+2_ion)GSNGVIMITTK MGYG000002478_01871 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,4P0HT@976|Bacteroidetes,2FPW8@200643|Bacteroidia,4AT1I@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5895278 4270452 -(ISD_z+2_ion)NILVINC(Carbamidomethyl)GSSSLK MGYG000000233_01457 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,21XHV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217140 0 0 0 0 0 0 0 1883554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1746755 0 0 0 0 2288151 0 0 343057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ISD_z+2_ion)QHPDLIDVPITGVGGIETWR MGYG000002528_01044 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1TRPI@1239|Firmicutes,24A0Z@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Dihydroorotate dehydrogenase 1.0 preA 1.0 - 1.0 1.3.1.1 1.0 ko:K17723 1.0 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 1.0 M00046 1.0 R00977,R01414,R11026 1.0 RC00072,RC00123 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHO_dh,Fer4_20,Fer4_21,Fer4_4,Fer4_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 dihydrouracil dehydrogenase (NAD(+)). - The enzyme was originally discovered in the uracil-fermenting bacterium, Clostridium uracilicum, which utilizes uracil and thymine as nitrogen and carbon sources for growth.-!-Since then the enzyme was found in additional organisms including Alcaligenes eutrophus, Pseudomonas strains and Escherichia coli. (1) 5,6-dihydrouracil + NAD(+) = H(+) + NADH + uracil. (2) 5,6-dihydrothymine + NAD(+) = H(+) + NADH + thymine. 1.0 1.0 1.0 1.0 Metabolic pathways;beta-Alanine metabolism;Pantothenate and CoA biosynthesis;Pyrimidine metabolism 1.0 none 1.0 0 163645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222915 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 523109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ISD_z+2_ion)SSLGALQNRLEHTVANLDNVAENTQSAESR MGYG000004271_01770 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ISD_z+2_ion)VIMIEDVTTSGK MGYG000002992_01058;MGYG000002528_00495;MGYG000000140_00157;MGYG000000206_02791;MGYG000000301_01060;MGYG000002393_00122;MGYG000001374_01050;MGYG000000217_01922;MGYG000002279_02444;MGYG000002756_01770;MGYG000000028_01453;MGYG000001141_00854;MGYG000000187_01588 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,27UZH@189330|Dorea 0.3076923076923077 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 984926 0 0 0 0 0 0 0 0 0 0 0 0 1653985 0 0 0 0 794104 0 0 0 0 0 0 0 0 0 0 0 0 0 443226 0 0 0 0 0 3275672 0 0 0 0 0 0 0 0 0 0 0 0 889351 0 0 0 0 1654524 0 0 0 0 0 0 0 0 0 0 2254207 0 0 1381273 0 0 0 0 0 1776146 0 0 0 0 0 0 0 0 0 0 0 0 1352716 0 0 0 0 1140873 0 0 0 0 0 0 0 0 0 0 1052445 0 0 1306325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3370079 0 0 0 0 0 0 0 0 0 0 0 0 2024123 0 0 0 0 1367066 0 0 0 0 0 0 0 0 0 0 1557264 0 0 0 0 0 0 0 -(ISD_z+2_ion)VMIIEDVTTSGK MGYG000000179_05171 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,267V0@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1626184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ISD_z+2_ion)VNLCGGGFTGQSQALR MGYG000004748_03238;MGYG000002560_02422;MGYG000004479_00779;MGYG000000043_00067;MGYG000001599_02778;MGYG000000196_04089;MGYG000004185_02065;MGYG000004019_01937;MGYG000003681_02137;MGYG000002171_01962;MGYG000003367_01578;MGYG000002291_02395;MGYG000001780_01719;MGYG000004899_04130;MGYG000001787_00222;MGYG000001306_01211;MGYG000003693_02546;MGYG000001835_01928;MGYG000002281_00009;MGYG000000781_00884;MGYG000002455_03781;MGYG000001346_00647;MGYG000000243_02463;MGYG000000042_00637;MGYG000001783_00061;MGYG000001370_01952;MGYG000003363_02163 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,2FSGZ@200643|Bacteroidia,4AQR7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 1.0 rpsI 1.0 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3385219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ISD_z+2_ion)VVVTGVEMFR MGYG000001234_01151;MGYG000000120_01190;MGYG000002854_00111;MGYG000000420_01950;MGYG000004847_01222;MGYG000001623_00993;MGYG000002837_02416;MGYG000002528_01098;MGYG000002901_00528;MGYG000000016_02519;MGYG000004285_00597;MGYG000004718_00646;MGYG000002563_00509;MGYG000004565_01266;MGYG000000262_00030;MGYG000000433_00368;MGYG000002563_00522;MGYG000001315_01207;MGYG000000177_01044;MGYG000004642_00846;MGYG000002290_01325;MGYG000002854_00124;MGYG000002234_01026 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,25QFW@186804|Peptostreptococcaceae 0.30434782608695654 186801|Clostridia 0.9565217391304348 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9565217391304348 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702117 0 0 0 0 0 0 688955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496465 423456 0 0 0 0 0 0 0 0 0 823345 0 370849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 884592 688116 0 0 0 0 0 0 0 0 0 896026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ISD_z+2_ion)WSNGDPVTANDFVYAWHR MGYG000000045_02091 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG4166@1|root,COG4166@2|Bacteria,2NPWR@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788100 0 0 0 0 567438 0 0 0 0 856563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(ISD_z+2_ion)YKEAYELLTGK MGYG000003694_01732 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter faecis|m__MGYG000003694 1.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,2483I@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 SAICAR synthetase 1.0 purC 1.0 - 1.0 6.3.2.6 1.0 ko:K01923 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04591 1.0 RC00064,RC00162 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 SAICAR_synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase. SAICAR synthetase. Forms part of the purine biosynthesis pathway. 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate + ADP + 2 H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Iminobiotin)AAEHVVGVAQGVSEDILADLR MGYG000000255_00995 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 827259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331197 0 0 0 0 0 0 0 354221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162292 0 0 0 0 356100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1840778 0 0 0 0 497518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 393995 0 0 0 0 181386 0 0 766961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1401277 0 0 0 0 556998 -(Iminobiotin)TNCCCTIGLGGGK MGYG000002966_00993 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900551075|m__MGYG000002966 1.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,36ED1@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Dehydrogenase 1.0 dhaD 1.0 - 1.0 1.1.1.6 1.0 ko:K00005 1.0 ko00561,ko00640,ko01100,map00561,map00640,map01100 1.0 - 1.0 R01034,R10715,R10717 1.0 RC00029,RC00117,RC00670 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol dehydrogenase. NAD-linked glycerol dehydrogenase. Also acts on 1,2-propanediol. glycerol + NAD(+) = dihydroxyacetone + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1209883 0 0 0 0 593472 -(Iodoacetanilide)AAALQPGEVLLLENLR MGYG000000196_04506;MGYG000000013_01224;MGYG000003681_00986;MGYG000002549_02739;MGYG000001661_02348;MGYG000003922_03393;MGYG000004876_02584 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 389600 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1365499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Iodoacetanilide)EIAEISEDKR MGYG000000255_01812;MGYG000000198_04915 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,21XI7@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 - 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4728621 0 0 0 0 0 0 2575945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2186146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Iodoacetanilide)FMAAIEAALEKGDVEAAK MGYG000002561_00509;MGYG000001313_03230 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Iodoacetanilide)GITNKVSDVDISEFYR MGYG000000255_01008 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 832994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Iodoacetanilide)IAPVFTDDEDQSR MGYG000000179_05046 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 99691 0 145641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307348 0 0 97683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19179450 0 6826365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8571042 0 7339615 0 0 20109453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Iodoacetanilide)LIEWVLWNSER MGYG000000243_02761 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1803@1|root,COG1803@2|Bacteria,4NQJ9@976|Bacteroidetes,2FPT5@200643|Bacteroidia,4ANEX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 methylglyoxal synthase 1.0 mgsA 1.0 - 1.0 4.2.3.3 1.0 ko:K01734 1.0 ko00640,ko01120,map00640,map01120 1.0 - 1.0 R01016 1.0 RC00424 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylglyoxal synthase. - Does not act on D-glyceraldehyde 3-phosphate.-!-Formerly EC 4.2.99.11. dihydroxyacetone phosphate = methylglyoxal + phosphate. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10661698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Iodoacetanilide)LYDFLDSSK MGYG000004697_00401 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eubacterium_F|s__|m__MGYG000004697 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,25VKP@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 996169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Iodoacetanilide)SETFSTAADNQSEVTIHVLQGER MGYG000000196_01218 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,4ANVI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Iodoacetanilide_13C(6))DKTVTENTR MGYG000000258_01582 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Ruminococcus_E|s__Ruminococcus_E bromii_B|m__MGYG000000258 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia 1.0 186801|Clostridia 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 3749243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 787375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1058418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2995923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(LG-anhyropyrrole)INPESDLVEIVEIPTLK MGYG000001306_01353 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,2FMC4@200643|Bacteroidia,4AMIN@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates 1.0 pyrG 1.0 - 1.0 6.3.4.2 1.0 ko:K01937 1.0 ko00240,ko01100,map00240,map01100 1.0 M00052 1.0 R00571,R00573 1.0 RC00010,RC00074 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CTP_synth_N,GATase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CTP synthase (glutamine hydrolyzing). UTP--ammonia ligase. The enzyme contains three functionally distinct sites: an allosteric GTP-binding site, a glutaminase site where glutamine hydrolysis occurs (cf. EC 3.5.1.2), and the active site where CTP synthesis takes place.-!-The reaction proceeds via phosphorylation of UTP by ATP to give an activated intermediate 4-phosphoryl UTP and ADP.-!-Ammonia then reacts with this intermediate generating CTP and a phosphate.-!-The enzyme can also use ammonia from the surrounding solution. ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(LG-anhyropyrrole)LDAIHDTVHEMAR MGYG000002517_02838;MGYG000002961_00635 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.5 186801|Clostridia 0.5 C 1.0 Rubrerythrin 1.0 rbr3A 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(LG-anhyropyrrole)VGIALFLSHLAHEGK MGYG000000196_01613;MGYG000000042_02438;MGYG000000243_00830;MGYG000000098_01886;MGYG000002478_00044 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,2FM6E@200643|Bacteroidia,4ANM1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 8.96 1.0 glmM 1.0 - 1.0 5.4.2.8 1.0 ko:K01840 1.0 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 1.0 M00114 1.0 R01818 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphomannomutase. phosphomannose mutase. alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(LG-pyrrole)DLVLAPMMQGAVNYMHTGNR MGYG000000074_01125 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1834@1|root,COG1834@2|Bacteria,4NFQ7@976|Bacteroidetes,2FNG1@200643|Bacteroidia,22VJQ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8241855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13727568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2126201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Lys)NGGCGECQTSC(Carbamidomethyl)QSAC(Carbamidomethyl)K MGYG000004863_00663;MGYG000003961_01976 phylum d__Bacteria|p__Firmicutes_A 1.0 2EGRK@1|root,317VV@2|Bacteria,1U4MD@1239|Firmicutes,25N9S@186801|Clostridia,2N7T3@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Six-cysteine peptide SCIFF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SCIFF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 930217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Lys)RTAVQQEINQLASEITR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Lys)TYAMQTVHGR MGYG000000243_01840 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,2FME7@200643|Bacteroidia,4AKME@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin 1.0 oorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00175 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Met-loss)MEALGM(Oxidation)IETK MGYG000002098_00283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01|s__|m__MGYG000002098 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,22HKK@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2413967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Met-loss)MEALGMIETK MGYG000002098_00283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01|s__|m__MGYG000002098 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,22HKK@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21671039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Met-loss+Acetyl)MAIADLDKQPDSVSSVLK MGYG000003372_02465;MGYG000002494_03392;MGYG000002535_01618 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 2D4RX@1|root,2SW2Q@2759|Eukaryota 0.6666666666666666 2759|Eukaryota 0.6666666666666666 S 0.6666666666666666 helix_turn_helix isocitrate lyase regulation 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 HTH_IclR,IclR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2168386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2462786 0 1628753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Met-loss+Acetyl)MAKEKFER MGYG000003142_01865;MGYG000000196_03974;MGYG000003142_01879;MGYG000002528_01098;MGYG000001346_01533;MGYG000001630_01142;MGYG000001313_00097;MGYG000000243_01988;MGYG000003266_00392;MGYG000000236_01807;MGYG000003514_00785;MGYG000004763_01689;MGYG000001485_02164 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.38461538461538464 976|Bacteroidetes 0.5384615384615384 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9230769230769231 tuf 1.0 - 0.8461538461538461 - 1.0 ko:K02358 0.9230769230769231 - 0.9230769230769231 - 0.9230769230769231 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9230769230769231 - 0.9230769230769231 - 1.0 - 0.9230769230769231 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9230769230769231 none 1.0 0 684239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1340723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Met-loss+Acetyl)MAKEKYER MGYG000003683_00887 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Met-loss+Acetyl)MSEQNNTEMAFQIQR MGYG000002494_02265;MGYG000002535_04413;MGYG000003372_03408 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,3WXY5@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 U 1.0 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA 1.0 secB 1.0 GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 1.0 - 1.0 ko:K03071 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044,ko03110 1.0 3.A.5 1.0 - 1.0 - 1.0 SecB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 956586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1204543 0 584898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Met-loss+Acetyl)MSKEKFER MGYG000001692_03322;MGYG000002535_04656;MGYG000003363_01661;MGYG000002506_03686;MGYG000002506_02966 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,3ZITI@590|Salmonella 0.8 1236|Gammaproteobacteria 0.8 J 1.0 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.8 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 2306081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3801918 0 0 0 0 0 0 2108657 0 0 0 4202467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5647115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4365057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5830275 0 5511407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10027246 0 0 0 0 0 0 0 0 11029598 0 0 0 0 12054238 -(Met-loss+Acetyl)MSMSDDTHNSLSTGK MGYG000002494_01908 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0685@1|root,KOG0564@2759|Eukaryota 1.0 2759|Eukaryota 1.0 E 1.0 methylenetetrahydrofolate reductase (NAD(P)H) activity 1.0 MTHFR1 1.0 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.0 1.5.1.20,3.6.4.12 1.0 ko:K00297,ko:K10901 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko03440,ko03460,map00670,map00720,map01100,map01120,map01200,map01523,map03440,map03460 1.0 M00295,M00377,M00414 1.0 R01224,R07168 1.0 RC00081 1.0 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 1.0 - 1.0 - 1.0 - 1.0 BT1,DEAD,DUF1712,EamA,Helicase_C,Homoserine_dh,Hormone_recep,MTHFR,RecQ_Zn_bind,peroxidase,zf-C4 1.0 - 1.0 - 1.0 - 1.0 AA0 1.0 methylenetetrahydrofolate reductase [NAD(P)H]. | DNA helicase. MTHFR. A flavoprotein (FAD).-!-The enzyme catalyzes the reversible conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, playing an important role in folate metabolism by regulating the distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis.-!-This enzyme, characterized from Protozoan parasites of the genus Leishmania, is unique among similar characterized eukaryotic enzymes in that it lacks the C-terminal allosteric regulatory domain (allowing it to catalyze a reversible reaction) and uses NADH and NADPH with equal efficiency under physiological conditions. cf. EC 1.5.1.53, EC 1.5.1.54, and EC 1.5.7.1.-!-Formerly EC 1.1.1.68, EC 1.1.1.171, EC 1.1.99.15 and EC 1.7.99.5. | DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA.-!-Some of them unwind duplex DNA with a 3' to 5' polarity, other show 5' to 3' polarity or unwind DNA in both directions.-!-Some helicases unwind DNA as well as RNA.-!-May be identical with EC 3.6.4.13. (1) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH. (2) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH. | ATP + H2O = ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 Fanconi anemia pathway;Carbon metabolism;Homologous recombination;Carbon fixation pathways in prokaryotes;Metabolic pathways;Antifolate resistance;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2093754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Met-loss+Acetyl)MSNVIVKDNESLDSALR MGYG000000087_00069;MGYG000000255_00059 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 1.0 203691|Spirochaetes 1.0 L 1.0 PFAM Integrase core domain 1.0 - 1.0 - 1.0 - 1.0 ko:K07497 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 881644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531165 0 0 0 0 0 0 0 0 0 0 753405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 414670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Met-loss+Acetyl)MSNVIVKDNESLDSALRR MGYG000000087_00069;MGYG000000255_00059 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 1.0 203691|Spirochaetes 1.0 L 1.0 PFAM Integrase core domain 1.0 - 1.0 - 1.0 - 1.0 ko:K07497 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 980751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858672 0 0 0 0 0 0 0 0 0 0 497674 0 1279894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1532632 0 0 0 0 0 0 0 0 0 0 1695489 0 870404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 440804 0 0 0 0 0 0 0 0 0 0 671208 0 335467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 831248 0 0 0 0 0 0 0 0 0 0 1073052 0 431467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216384 0 0 0 0 0 0 0 0 0 0 2292709 0 -(Met-loss+Acetyl)MTAVENAAVSQEELDAK MGYG000001292_01825 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 Pyruvate formate lyase-like 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bac_luciferase,Fer4_12,Gly_radical,PFL-like,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 625192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Met-loss+Acetyl)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AASSESFGYNEDPIVSSDVIGMR MGYG000001157_00577 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540775|m__MGYG000001157 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4661388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5242856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AAVEEGIIPGGGVAYIR MGYG000000170_00603 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900240235|m__MGYG000000170 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22UPC@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2584432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AAVEEGIVPGGGVAYIR MGYG000001562_02467;MGYG000004469_00981;MGYG000003469_01417;MGYG000001302.1_02015;MGYG000003467_00265;MGYG000004658_01438;MGYG000000074_00757;MGYG000001546_00436;MGYG000000003_00613;MGYG000003279_00515 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22UPC@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2526331 0 0 0 0 0 0 0 0 0 0 0 2254615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AEDLKELYVLPENDLK MGYG000000198_05929 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,21ZAM@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2117428 0 0 0 0 0 0 0 0 0 0 539678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 439271 0 0 0 0 0 0 0 0 0 0 1722852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AGADLLVLAYHR MGYG000000077_01037;MGYG000000142_02711;MGYG000004839_00803;MGYG000000187_00408;MGYG000002098_00381;MGYG000000078_00616;MGYG000004317_01742;MGYG000004055_01306;MGYG000000206_00137;MGYG000000018_00879;MGYG000002156_00398;MGYG000000562_00802;MGYG000000690_00596;MGYG000000262_02262;MGYG000000216_01929;MGYG000000146_01522;MGYG000002756_03331;MGYG000001658_00185;MGYG000000352_00144;MGYG000000356_02067;MGYG000000193_02344 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae 0.8571428571428571 186801|Clostridia 0.9523809523809523 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily 1.0 rfbB 1.0 - 1.0 4.2.1.46 0.9523809523809523 ko:K01710 0.9523809523809523 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 0.9523809523809523 M00793 0.9523809523809523 R06513 0.9523809523809523 RC00402 0.9523809523809523 ko00000,ko00001,ko00002,ko01000 0.9523809523809523 - 1.0 - 1.0 - 1.0 GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 GT2 0.7142857142857143 dTDP-glucose 4,6-dehydratase. - - dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. 0.9523809523809523 0.9523809523809523 0.9523809523809523 0.9523809523809523 Acarbose and validamycin biosynthesis;Biosynthesis of vancomycin group antibiotics;Polyketide sugar unit biosynthesis;Streptomycin biosynthesis 0.9523809523809523 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AGDDAAGLAISEK MGYG000001615_01518;MGYG000000152_01227;MGYG000001334_01184;MGYG000000198_00788;MGYG000001496_01497;MGYG000001615_02187;MGYG000000150_03902;MGYG000000099_02202;MGYG000001617_02963;MGYG000000099_03212;MGYG000001311_05635;MGYG000001504_03254;MGYG000000024_00320;MGYG000002949_03375;MGYG000000090_01557;MGYG000001334_01190;MGYG000001615_01520;MGYG000003215_01405;MGYG000001496_01502;MGYG000000179_04407;MGYG000001496_01500;MGYG000002421_00363;MGYG000001470_01217;MGYG000000264_02727;MGYG000004541_00237;MGYG000000915_01790;MGYG000001571_00647;MGYG000000323_01374;MGYG000001470_04423;MGYG000004831_00621;MGYG000001470_04044;MGYG000001500_00161;MGYG000000152_03627 domain d__Bacteria 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,21Z1P@1506553|Lachnoclostridium 0.30303030303030304 186801|Clostridia 0.7272727272727273 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9696969696969697 hag 0.8484848484848485 - 0.7272727272727273 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.6060606060606061 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7703081 0 0 0 0 0 0 0 0 6686324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AGGYNMVSSVNDTYR MGYG000000217_02614 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Acetatifactor|s__Acetatifactor sp900066565|m__MGYG000000217 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3899843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AKEEFVR MGYG000002293_00521;MGYG000003697_01485 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0050@1|root,COG0050@2|Bacteria,4P1C5@976|Bacteroidetes,2FX1Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 396767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287738 0 0 0 0 0 0 0 193128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 349840 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29133985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14589689 0 21035984 0 0 0 0 21285956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AKEKFDR MGYG000004756_01173;MGYG000001415_02515;MGYG000002438_02321;MGYG000004658_01205;MGYG000004288_00862;MGYG000002972_00178;MGYG000003516_01606;MGYG000003542_01415;MGYG000001562_01075;MGYG000000045_02616;MGYG000000254_02569;MGYG000000074_01773;MGYG000003279_00951;MGYG000001470_03722;MGYG000000044_01721;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000000223_03134;MGYG000001400_03001 life d__Bacteria 0.9474 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 0.47368421052631576 976|Bacteroidetes 0.631578947368421 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.8421052631578947 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.9473684210526315 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64335 0 0 0 0 0 0 0 25703 0 232346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199776 0 0 0 0 0 0 0 590718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1479578 0 0 0 0 0 0 0 0 0 37064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444840 0 0 0 0 0 0 0 80052 0 14131 0 0 0 0 0 0 0 -(Methyl)AKEKFER MGYG000000042_01421;MGYG000002106_00224;MGYG000001524_01606;MGYG000001630_01142;MGYG000002485_02622;MGYG000004893_01944;MGYG000004893_00932;MGYG000003460_01161;MGYG000003155_00314;MGYG000001925_01419;MGYG000000273_00431;MGYG000001701_00473;MGYG000004763_01689;MGYG000003681_02037;MGYG000001384_04567;MGYG000001464_00103;MGYG000002281_02290;MGYG000003185_01074;MGYG000003992_01709;MGYG000003142_01879;MGYG000002528_01098;MGYG000001313_00097;MGYG000000013_02251;MGYG000003266_00392;MGYG000003583_01411;MGYG000002455_03884;MGYG000000348_00283;MGYG000003628_01000;MGYG000001485_02164;MGYG000000034_01346;MGYG000001141_02439;MGYG000002930_00867;MGYG000003142_01865;MGYG000000196_03974;MGYG000003375_00698;MGYG000004573_00004;MGYG000001661_02666;MGYG000003851_00676;MGYG000002762_01733;MGYG000000121_02189;MGYG000001789_00154;MGYG000001567_01738;MGYG000000182_00585;MGYG000000054_03933;MGYG000000236_01807;MGYG000000098_02017;MGYG000002291_02272;MGYG000003185_01053;MGYG000002556_01332;MGYG000000036_01380;MGYG000000445_01370;MGYG000001346_01533;MGYG000000243_01988;MGYG000001780_03476;MGYG000002540_03367;MGYG000001646_01118;MGYG000003073_01160;MGYG000003514_00785;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.23728813559322035 976|Bacteroidetes 0.4915254237288136 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9830508474576272 tuf 1.0 - 0.847457627118644 - 1.0 ko:K02358 0.9830508474576272 - 0.9830508474576272 - 0.9830508474576272 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9830508474576272 - 0.9830508474576272 - 1.0 - 0.9491525423728814 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9830508474576272 none 1.0 1323520 5014016 761927 1265284 4936830 613296 414322 1132323 794009 1238467 976466 1227882 1565935 2621112 965248 1036846 1558673 794050 949648 39971 1104889 422472 480844 1479437 1206540 938370 1182932 326152 727697 970637 8537718 647577 3205418 791620 1894943 622421 1669135 2715062 908867 3907080 1684027 498600 5398220 8838983 1169784 735151 190700 1422349 3426961 1974518 2402947 2179464 985939 9904334 3871971 1086867 2809866 349682 2431192 10281859 2658159 7454875 7229375 363285 663385 899365 9291523 1484799 751668 1666656 2130348 621762 403028 649443 603941 6755236 1602596 647035 275197 339188 246755 569800 641506 423726 186867 597099 782571 168391 553032 307474 223220 462286 1715003 31691 252781 255912 301933 236180 403926 1182713 462102 2391026 336570 319007 162210 207483 448548 224721 414071 289829 674558 498277 220632 241743 271500 0 1022074 371733 687260 770099 580463 658365 2373308 281029 3448333 2514002 3830141 756495 479739 1492526 171339 2129966 967808 166217 2601335 341549 1146627 510025 722565 882281 96311 3356769 98162 187478 1101393 538305 394755 119194 587752 958733 1183003 537927 3894783 3732409 701738 707887 2842788 5362876 457995 3438292 5848879 246467 910166 1233258 3389820 565523 1880784 6319160 5586806 4229669 503851 7264948 670582 620048 4049470 923990 1697498 4852755 915206 0 572354 2427318 260906 646269 796461 774549 13739183 609976 5680830 401707 -(Methyl)AKEQFQR MGYG000001881_00748 genome d__Bacteria|p__Verrucomicrobiota|c__Verrucomicrobiae|o__Verrucomicrobiales|f__Akkermansiaceae|g__Akkermansia|s__Akkermansia muciniphila_A|m__MGYG000001881 1.0 COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,2ITQE@203494|Verrucomicrobiae 1.0 203494|Verrucomicrobiae 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AKTETHIPAVIDTAEALEAK MGYG000000133_00993;MGYG000000301_01128 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 84362 0 0 0 0 0 0 0 0 0 0 0 0 56321 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71096 322306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2116302 1929282 2169706 0 0 2399104 0 0 0 0 0 0 2598604 0 1458987 2135995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2298380 0 0 1405093 0 0 -(Methyl)ALVPMVIEQTSR MGYG000003372_00321;MGYG000002535_03209;MGYG000002534_01240;MGYG000002494_00469 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,3WVQ6@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 OU 1.0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins 1.0 clpP 1.0 GO:0000502,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017171,GO:0019538,GO:0019899,GO:0030163,GO:0031597,GO:0032991,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051117,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 1.0 3.4.21.92 1.0 ko:K01358 1.0 ko04112,ko04212,map04112,map04212 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 CLP_protease 1.0 - 1.0 - 1.0 - 1.0 - 1.0 endopeptidase Clp. protease Ti. Belongs to peptidase family S14. Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs). 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Cell cycle - Caulobacter 1.0 none 1.0 0 0 432363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3966508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4856959 0 0 0 0 0 0 0 418394 0 0 0 394366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 526129 0 0 0 0 0 0 0 0 0 0 0 490196 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)ASNLLYTR MGYG000002494_00829 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,1RR4N@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 P 1.0 During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction 1.0 dps 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005623,GO:0006950,GO:0008150,GO:0008199,GO:0009289,GO:0009295,GO:0009605,GO:0009991,GO:0031667,GO:0042594,GO:0042802,GO:0042995,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0097159,GO:1901363 1.0 - 1.0 ko:K04047 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03036 1.0 - 1.0 - 1.0 - 1.0 Ferritin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1796961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)ATGEVMAIGR MGYG000000335_00337 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Enterococcaceae|g__Enterococcus_G|s__Enterococcus_G italicus|m__MGYG000000335 1.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,4AZM7@81852|Enterococcaceae 1.0 91061|Bacilli 1.0 EF 1.0 carbamoyl-phosphate synthetase ammonia chain 1.0 carB 1.0 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1211516 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AVAGVMNIETK MGYG000000074_02206 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,2FP7Y@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 O 1.0 Peptidase family M13 1.0 pepO 1.0 - 1.0 3.4.24.71 1.0 ko:K01415,ko:K07386 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002,ko04147 1.0 - 1.0 - 1.0 - 1.0 Peptidase_M13,Peptidase_M13_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 endothelin-converting enzyme 1. ECE-1. Phosphoramidon-sensitive.-!-Belongs to peptidase family M13. Hydrolysis of the 21-Trp-|-Val-22 bond in big endothelin to form endothelin 1. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1629959 0 0 -(Methyl)AVEAVDEC(Carbamidomethyl)VGK MGYG000003684_05297;MGYG000000249_01356 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,27JMY@186928|unclassified Lachnospiraceae 0.5 186801|Clostridia 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 - 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Metalloenzyme,PglZ,Phosphodiest,iPGM_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AVNTAVEAVK MGYG000003937_00155 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3WGUG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AVSAKDVMELR MGYG000003937_00036 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AVVGANWGDEGKGK MGYG000000171_01836;MGYG000000515_02290;MGYG000004785_00710;MGYG000000200_00992;MGYG000002528_02635;MGYG000002202_00641;MGYG000000136_00460;MGYG000000213_00509;MGYG000003324_01888;MGYG000004039_01400;MGYG000001338_02654;MGYG000000201_00874;MGYG000004593_02178;MGYG000004735_01537;MGYG000003425_00268;MGYG000000245_00501;MGYG000004719_01729;MGYG000000133_00154;MGYG000000184_00060;MGYG000000018_01545;MGYG000001607_00542;MGYG000000212_03119;MGYG000001652_00002;MGYG000004697_01453;MGYG000000031_02099;MGYG000000142_01890;MGYG000000251_00296;MGYG000000141_03421;MGYG000003702_00960;MGYG000004740_00439;MGYG000000389_00666;MGYG000002517_01833;MGYG000004733_01110;MGYG000002945_01173;MGYG000002234_01353;MGYG000002298_00432;MGYG000000404_00404;MGYG000000216_02589;MGYG000003422_00451 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3XYKX@572511|Blautia 0.48717948717948717 186801|Clostridia 1.0 F 1.0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP 1.0 purA 1.0 - 1.0 6.3.4.4 1.0 ko:K01939 1.0 ko00230,ko00250,ko01100,map00230,map00250,map01100 1.0 M00049 1.0 R01135 1.0 RC00458,RC00459 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Adenylsucc_synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adenylosuccinate synthase. succinoadenylic kinosynthetase. - GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 882817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)AVVTGVEMFR MGYG000000323_00619;MGYG000000277_00173;MGYG000001558_01002;MGYG000004789_00520 order d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,42CX2@671232|Streptococcus anginosus group 0.5 91061|Bacilli 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 1.0 - 1.0 ko:K02358,ko:K15771 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 754932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 826004 0 0 0 0 0 0 0 0 0 0 391064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 345577 0 0 0 0 0 0 0 0 0 0 231565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485986 0 0 0 0 0 0 0 0 0 0 362557 0 -(Methyl)DALGMIETK MGYG000000150_00816;MGYG000000179_01371;MGYG000000198_01506;MGYG000000150_00833 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 0.75 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 0.75 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12028563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22225482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DASATALYGSR MGYG000003922_01771;MGYG000000348_01754;MGYG000001780_01242;MGYG000001313_00412;MGYG000001346_02561;MGYG000003362_02386;MGYG000003533_00526;MGYG000001655_02726;MGYG000001345_04490;MGYG000000105_01162;MGYG000000098_00457;MGYG000002171_00691;MGYG000004876_03126;MGYG000001780_03810;MGYG000002478_01858;MGYG000004588_02518;MGYG000003202_01776;MGYG000000013_04510;MGYG000002281_04203;MGYG000000183_04381;MGYG000001346_02568;MGYG000001641_01324;MGYG000004876_02392;MGYG000003498_00420;MGYG000002960_00779;MGYG000001780_00781;MGYG000003362_01220;MGYG000003697_02404;MGYG000004763_00489;MGYG000000168_01851;MGYG000001787_00133;MGYG000001345_03710;MGYG000001346_02291;MGYG000000437_00933;MGYG000000168_03318;MGYG000000673_00330;MGYG000004748_02928;MGYG000000196_00461;MGYG000003493_01627;MGYG000004823_00190;MGYG000000354_01804;MGYG000002478_01871;MGYG000004763_00494;MGYG000004876_03105;MGYG000003363_01827;MGYG000000196_03064;MGYG000000224_00771;MGYG000003367_00895;MGYG000002721_00156;MGYG000002478_00956;MGYG000004876_02902;MGYG000001661_00787;MGYG000001780_00996;MGYG000004797_01968;MGYG000000196_03113;MGYG000004561_00722;MGYG000001337_03660;MGYG000004797_00001;MGYG000004763_01369;MGYG000004876_02476;MGYG000004479_01532;MGYG000004464_01616;MGYG000000354_00270;MGYG000004876_00176;MGYG000003922_02156;MGYG000001345_04437;MGYG000001345_04559;MGYG000002478_00565;MGYG000000224_01718;MGYG000003493_02187;MGYG000001661_01127;MGYG000001313_01021;MGYG000000196_00132;MGYG000004899_00292;MGYG000001789_00592;MGYG000004495_02402;MGYG000001433_00908;MGYG000003223_00188;MGYG000000236_00420;MGYG000000183_02560;MGYG000000013_00507;MGYG000002455_01818;MGYG000004797_01501;MGYG000001378_02925;MGYG000000243_02340;MGYG000003922_01732;MGYG000001780_02437;MGYG000001783_00603;MGYG000003423_01221;MGYG000002293_02867;MGYG000003363_02178;MGYG000001780_02820;MGYG000002478_00743;MGYG000000825_01952;MGYG000000781_00147;MGYG000003460_00442;MGYG000000105_01229;MGYG000003233_02240;MGYG000001789_02867;MGYG000002293_02874;MGYG000001345_01594;MGYG000004464_01003;MGYG000002556_00559;MGYG000004797_01285;MGYG000004797_01842;MGYG000004876_02563;MGYG000003164_00175;MGYG000002905_01072;MGYG000002561_01649 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia,4ANGT@815|Bacteroidaceae 0.21100917431192662 976|Bacteroidetes 0.9908256880733946 P 0.9174311926605505 TonB-linked outer membrane protein, SusC RagA family 0.7064220183486238 - 0.7064220183486238 - 0.9541284403669725 - 1.0 - 0.6055045871559633 - 1.0 - 1.0 - 1.0 - 1.0 - 0.6055045871559633 - 0.6055045871559633 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.7981651376146789 - 1.0 - 1.0 - 1.0 - 0.9724770642201835 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DATMAQLGR MGYG000000201_03110;MGYG000000806_01492;MGYG000003012_02207 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1485340 0 0 0 0 0 -(Methyl)DFAENEVKPLAAEIDEEERFPMETVEK MGYG000002794_01608;MGYG000002720_01506 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2N683@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Psort location Cytoplasmic, score 9.97 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 2149254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1249924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DFLLDMSDAGK MGYG000000171_02044 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3XYWE@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1072756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DFLLSEVR MGYG000004718_01473;MGYG000000016_02335 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,36EA6@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 - 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_10,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1263777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DGAATAIYGSR MGYG000002438_02058 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,4NDXS@976|Bacteroidetes,2G0KF@200643|Bacteroidia,22XIH@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DGEDPGYTLYDLSER MGYG000002515_02735;MGYG000002506_00791;MGYG000002323_02099;MGYG000002506_03156;MGYG000002515_01515;MGYG000002323_00193 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,1RNSQ@1236|Gammaproteobacteria,3XMMA@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria 1.0 gadB 0.6666666666666666 GO:0003674,GO:0003824,GO:0004351,GO:0006873,GO:0006885,GO:0008150,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019725,GO:0030003,GO:0030004,GO:0030641,GO:0042592,GO:0045852,GO:0048878,GO:0050801,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 1.0 4.1.1.15 1.0 ko:K01580 1.0 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 1.0 M00027 1.0 R00261,R00489,R01682,R02466 1.0 RC00299 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECUMN_1333.ECUMN_1747,iUTI89_1310.UTI89_C1707,ic_1306.c1922 0.6666666666666666 Pyridoxal_deC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate decarboxylase. L-glutamate 1-carboxy-lyase. The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate. H(+) + L-glutamate = 4-aminobutanoate + CO2. 1.0 1.0 1.0 1.0 GABAergic synapse;Type I diabetes mellitus;Taurine and hypotaurine metabolism;Butanoate metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Quorum sensing;beta-Alanine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DGWKLPDMPR MGYG000002218_00631;MGYG000000074_01657;MGYG000000174_02762 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,22ZVD@171551|Porphyromonadaceae 0.6666666666666666 976|Bacteroidetes 0.6666666666666666 S 0.6666666666666666 Oxidoreductase family, NAD-binding Rossmann fold 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal 0.6666666666666666 - 1.0 GH109 1.0 - 1.0 - 1.0 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DGWRLPDMPR MGYG000001378_04108;MGYG000000013_01888 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,4AP35@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tat pathway signal sequence domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal 1.0 - 1.0 GH109 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1462264 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DIALAYASGIGAGR MGYG000000022_01738;MGYG000004679_00185;MGYG000002641_01737;MGYG000000636_00571;MGYG000001300_02737;MGYG000003899_01538;MGYG000000039_02617;MGYG000002545_01021;MGYG000002651_01532;MGYG000002610_02042;MGYG000003291_01288 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3WGY4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 708248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596018 0 -(Methyl)DILSSVFR MGYG000004797_01140 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia,4ANV3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 ATPase histidine kinase DNA gyrase B HSP90 domain protein 1.0 htpG 1.0 - 1.0 - 1.0 ko:K04079 1.0 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HATPase_c_3,HSP90 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Estrogen signaling pathway;Antigen processing and presentation;Necroptosis;Prostate cancer;NOD-like receptor signaling pathway;Plant-pathogen interaction;Protein processing in endoplasmic reticulum;Th17 cell differentiation;Progesterone-mediated oocyte maturation;Fluid shear stress and atherosclerosis;Pathways in cancer;IL-17 signaling pathway;PI3K-Akt signaling pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DIQINIFEVK MGYG000001345_04705;MGYG000000029_02795;MGYG000001056_01155;MGYG000000196_03995;MGYG000000236_01781;MGYG000000243_01965;MGYG000001346_01513;MGYG000003697_01462;MGYG000001378_05021;MGYG000001337_03883;MGYG000000054_03864;MGYG000002080_00547;MGYG000000224_00470;MGYG000002293_00499;MGYG000003681_02057;MGYG000001370_01701;MGYG000002834_00446;MGYG000002549_02919;MGYG000003363_02285 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,2FMYX@200643|Bacteroidia,22W3B@171551|Porphyromonadaceae 0.7368421052631579 976|Bacteroidetes 1.0 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 1.0 rpsC 1.0 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02982 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858034 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DIVAYAAER MGYG000000053_01764 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp002358415|m__MGYG000000053 1.0 COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,2FNAR@200643|Bacteroidia,4AKUS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Glycosyl hydrolase family 20, catalytic domain protein 1.0 - 1.0 - 1.0 3.2.1.52 1.0 ko:K12373 1.0 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 1.0 M00079 1.0 R00022,R06004,R11316 1.0 RC00049 1.0 ko00000,ko00001,ko00002,ko01000,ko03110 1.0 - 1.0 GH20 1.0 - 1.0 CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b 1.0 3.2.1.52|3.2.1.- 1.0 GH20 1.0 GH20 1.0 GH20 1.0 beta-N-acetylhexosaminidase. N-acetyl-beta-glucosaminidase. Acts on N-acetylglucosides and N-acetylgalactosides.-!-Formerly EC 3.2.1.29 and EC 3.2.1.30. Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Glycosaminoglycan degradation;Glycosphingolipid biosynthesis - globo and isoglobo series;Other glycan degradation;Lysosome;Metabolic pathways;Glycosphingolipid biosynthesis - ganglio series;Various types of N-glycan biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1376800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DLEADFLK MGYG000001364_00421;MGYG000000029_02970;MGYG000001306_01781;MGYG000000442_00741;MGYG000002171_00856;MGYG000001835_00781;MGYG000000243_00367;MGYG000003693_03255;MGYG000001750_00740;MGYG000002549_01442;MGYG000001599_02900 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,2FMET@200643|Bacteroidia,4AKSS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2403625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DLPAFIIK MGYG000000201_02693;MGYG000001315_00492;MGYG000002994_00468;MGYG000001622_03187;MGYG000002186_00606;MGYG000000171_02133;MGYG000002966_03863;MGYG000000050_02427;MGYG000001439_01955;MGYG000001338_01256;MGYG000000184_00355;MGYG000001379_01879;MGYG000000262_00002 domain d__Bacteria 1.0 COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,3XZ23@572511|Blautia 0.46153846153846156 186801|Clostridia 0.9230769230769231 M 1.0 UDP-galactopyranose mutase 0.5384615384615384 glf 1.0 - 1.0 5.4.99.9 1.0 ko:K01854 1.0 ko00052,ko00520,map00052,map00520 1.0 - 1.0 R00505,R09009 1.0 RC00317,RC02396 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 GLF,NAD_binding_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 UDP-galactopyranose mutase. - - UDP-alpha-D-galactose = UDP-alpha-D-galactofuranose. 1.0 1.0 1.0 1.0 Galactose metabolism;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1181473 0 0 0 0 0 -(Methyl)DLYKNEIMDAMTKK MGYG000000142_02055 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,3WGYQ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits 1.0 rplE 1.0 - 1.0 - 1.0 ko:K02931 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L5,Ribosomal_L5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DMAEKVDAATK MGYG000002478_01081 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2465412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1996737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DMGHEVVEQFYEPDQLGK MGYG000002156_00958 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550585|m__MGYG000002156 1.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,2N6Y5@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 EH 1.0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1269105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DTNLSKKDVEAVLK MGYG000000031_02074;MGYG000000142_01875;MGYG000000216_00603 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3Y0HQ@572511|Blautia 1.0 186801|Clostridia 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hup 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)DVTLTYQLPK MGYG000001783_00567 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900551065|m__MGYG000001783 1.0 COG1629@1|root,COG3188@1|root,COG1629@2|Bacteria,COG3188@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4ANM7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 NPU 1.0 Psort location OuterMembrane, score 9.49 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3184705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)EGLFIDVTAR MGYG000002203_01195 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__|m__MGYG000002203 1.0 COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 813193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5085121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)EGNGSNPVR MGYG000000054_03245;MGYG000000196_02028;MGYG000000029_01424;MGYG000001378_01103 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,2FNA0@200643|Bacteroidia,4AM34@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems 1.0 sodB 1.0 - 1.0 1.15.1.1 1.0 ko:K04564 1.0 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Sod_Fe_C,Sod_Fe_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 superoxide dismutase. - - 2 H(+) + 2 superoxide = H2O2 + O2. 1.0 1.0 1.0 1.0 FoxO signaling pathway;MAPK signaling pathway - fly;Longevity regulating pathway - multiple species;Huntington disease;Peroxisome;Longevity regulating pathway;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1061543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)EVASEKYPAMK MGYG000000243_00044 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,2FNAR@200643|Bacteroidia,4AKUS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Glycosyl hydrolase family 20, catalytic domain protein 1.0 - 1.0 - 1.0 3.2.1.52 1.0 ko:K12373 1.0 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 1.0 M00079 1.0 R00022,R06004,R11316 1.0 RC00049 1.0 ko00000,ko00001,ko00002,ko01000,ko03110 1.0 - 1.0 GH20 1.0 - 1.0 CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b 1.0 3.2.1.52|3.2.1.- 1.0 GH20 1.0 GH20 1.0 GH20 1.0 beta-N-acetylhexosaminidase. N-acetyl-beta-glucosaminidase. Acts on N-acetylglucosides and N-acetylgalactosides.-!-Formerly EC 3.2.1.29 and EC 3.2.1.30. Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Glycosaminoglycan degradation;Glycosphingolipid biosynthesis - globo and isoglobo series;Other glycan degradation;Lysosome;Metabolic pathways;Glycosphingolipid biosynthesis - ganglio series;Various types of N-glycan biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1099624 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)EVELADAYQNTGAQLVK MGYG000004876_02137;MGYG000001313_00852;MGYG000003363_02977;MGYG000000224_01773;MGYG000000105_03063;MGYG000001661_02480;MGYG000003681_02583;MGYG000001370_00105;MGYG000001346_02504 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1544011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)EVIC(Carbamidomethyl)EIGYDSK MGYG000000262_02728;MGYG000000077_00332 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25V3W@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme 1.0 - 1.0 - 1.0 2.5.1.6 1.0 ko:K00789 1.0 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 1.0 M00034,M00035,M00368,M00609 1.0 R00177,R04771 1.0 RC00021,RC01211 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methionine adenosyltransferase. S-adenosylmethionine synthetase. Formerly EC 2.4.2.13. ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L- methionine. 1.0 1.0 1.0 1.0 Biosynthesis of amino acids;Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1303589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 883388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)EVTMQVK MGYG000000997_00886;MGYG000002963_04226;MGYG000000484_00676;MGYG000002098_01458;MGYG000004839_02458;MGYG000004271_02055;MGYG000002025_02130;MGYG000004884_01557;MGYG000000271_00295;MGYG000000268_00625;MGYG000002989_00657;MGYG000001658_01867;MGYG000000135_03501;MGYG000004735_02785;MGYG000001319_00742;MGYG000004712_00508;MGYG000000140_00956;MGYG000000245_00417;MGYG000001748_02093;MGYG000004891_01762;MGYG000000242_00062;MGYG000002517_01841;MGYG000000078_01452;MGYG000000356_00231 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2956962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3199425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2713887 2770669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)FDNAAEYTVGQEIK MGYG000001338_02807;MGYG000000200_01113;MGYG000000184_01172 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3XZ95@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit 1.0 rplC 1.0 - 1.0 - 1.0 ko:K02906 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 866927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 837347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 677907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)FGLADAGNIYGR MGYG000001300_02567;MGYG000001642_00033;MGYG000000280_02177;MGYG000000185_00279;MGYG000002978_00618;MGYG000002651_00281;MGYG000004087_02957;MGYG000002279_01466;MGYG000003486_01767;MGYG000004733_02577;MGYG000002298_00566;MGYG000002274_02337;MGYG000000252_02565;MGYG000000090_02004;MGYG000003266_00234;MGYG000000028_02056;MGYG000001315_02833;MGYG000002775_00932;MGYG000003361_00996;MGYG000000142_03199;MGYG000004740_00564;MGYG000001502_02222;MGYG000002445_01002;MGYG000000383_00104;MGYG000002040_00064;MGYG000001086_01260;MGYG000001567_00737;MGYG000001737_00599;MGYG000004519_00910;MGYG000000693_01345;MGYG000000212_00356;MGYG000000213_02746;MGYG000002272_02328;MGYG000000031_03298;MGYG000004681_00802;MGYG000002528_02771;MGYG000000195_01901;MGYG000000146_02288;MGYG000001456.1_01574;MGYG000000171_00165;MGYG000001338_01027;MGYG000000100_00277;MGYG000001303_02138;MGYG000002545_01885;MGYG000000291_00793;MGYG000000269_00514;MGYG000001636_01145;MGYG000000216_02897;MGYG000000038_00531;MGYG000002641_02488;MGYG000002050_00805;MGYG000002312_02592;MGYG000000140_01570;MGYG000002992_00682;MGYG000002065_00609;MGYG000003291_00536;MGYG000004679_00587;MGYG000000022_02103;MGYG000001645_01495;MGYG000003891_00287;MGYG000000164_02014;MGYG000001779_00982;MGYG000002919_00234;MGYG000002619_00737 domain d__Bacteria 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia 0.296875 186801|Clostridia 0.609375 E 0.890625 Psort location Cytoplasmic, score 9.98 0.328125 metY 0.546875 - 1.0 2.5.1.49 0.890625 ko:K01740 0.890625 ko00270,ko01100,map00270,map01100 0.890625 - 1.0 R01287,R04859 0.890625 RC00020,RC02821,RC02848 0.890625 ko00000,ko00001,ko01000 0.890625 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 0.609375 - 1.0 - 1.0 - 1.0 - 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 0.890625 0.890625 0.890625 0.890625 Cysteine and methionine metabolism;Metabolic pathways 0.890625 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1613503 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)FSLSQIVDAVSEK MGYG000001415_01540 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1376705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3388014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2174424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GAAEAYFGK MGYG000000098_00424 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides bouchesdurhonensis|m__MGYG000000098 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1039254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3200144 0 0 0 0 0 3100441 0 0 2936533 2456064 0 0 0 0 0 0 0 0 0 3154837 0 565773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1237207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351765 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1561986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GAMLTIMNPDDKAGLEAALR MGYG000003074_00586;MGYG000000028_00944;MGYG000000404_01798;MGYG000002141_01824;MGYG000001777_01059;MGYG000001367_03001;MGYG000003486_02521;MGYG000001617_02046;MGYG000002528_02668;MGYG000001615_04300 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 0.4 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 0.6 etfB 1.0 - 1.0 - 0.8 ko:K03521 0.8 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.8 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8 0.8 0.8 0.8 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675612 0 0 0 0 955053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GDFGYNAR MGYG000003763_00610;MGYG000000044_03505;MGYG000003351_04147;MGYG000003693_01240;MGYG000000196_04163;MGYG000003521_02097;MGYG000002171_01748;MGYG000001056_01919;MGYG000001659_02186;MGYG000003697_01689;MGYG000004899_00357;MGYG000003546_01342;MGYG000003353_01540;MGYG000004464_01712;MGYG000000029_01790;MGYG000001787_00205;MGYG000001433_02375;MGYG000001364_01313;MGYG000003251_00039;MGYG000000243_00634;MGYG000001763_00612;MGYG000001337_03744;MGYG000000215_01245;MGYG000000254_00174;MGYG000002051_00902;MGYG000001789_02329;MGYG000004495_01278;MGYG000002834_01380;MGYG000000355_02196;MGYG000002281_01780;MGYG000000013_01093;MGYG000003374_00724;MGYG000002478_00380;MGYG000003363_02977;MGYG000002218_01379;MGYG000003282_01136;MGYG000002293_01257;MGYG000000174_04760;MGYG000001925_02203;MGYG000001378_04618;MGYG000001306_00685;MGYG000001345_00379;MGYG000004763_01826;MGYG000002549_02837;MGYG000001770_01876;MGYG000002033_00862;MGYG000002438_00745;MGYG000002455_00111;MGYG000001489_00629;MGYG000000272_02397;MGYG000002133_00999;MGYG000002960_01776;MGYG000003252_04996;MGYG000000138_02067;MGYG000000117_00896;MGYG000004758_01391 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GFEIIK MGYG000001651_00562;MGYG000002549_01269;MGYG000000196_00779;MGYG000000098_01850 domain d__Bacteria 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 0.75 976|Bacteroidetes 0.75 H 0.75 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 0.75 pfp 0.75 - 1.0 2.7.1.11,2.7.1.90 0.75 ko:K00895,ko:K21071 0.75 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 0.75 - 1.0 R00756,R00764,R02073,R03236,R04779 0.75 RC00002,RC00017 0.75 ko00000,ko00001,ko01000 0.75 - 1.0 - 1.0 - 1.0 PFK 0.75 - 1.0 - 1.0 - 1.0 GT106 0.75 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 0.75 0.75 0.75 0.75 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 52716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2486123 0 0 0 0 0 0 0 0 0 0 1272323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GFELLK MGYG000000196_00779 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1664851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GFGIAMHTLDGGR MGYG000000080_01475;MGYG000002528_02667;MGYG000000204_00801;MGYG000000127_04022;MGYG000001793_01807;MGYG000002945_00737;MGYG000001615_04301;MGYG000000139_01931;MGYG000001564_00904;MGYG000000164_00686;MGYG000001315_01868;MGYG000001814_02502;MGYG000001617_02045;MGYG000000028_00943;MGYG000003486_02522 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.4 186801|Clostridia 1.0 C 0.6 acyl-CoA dehydrogenase 0.4666666666666667 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GGDDANTAFEK MGYG000000089_00652 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,3WGYK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1868568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1819490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GGMTGTALTEEKEFR MGYG000004733_00567;MGYG000000002_00058;MGYG000000212_01327;MGYG000000133_00962;MGYG000000142_00060 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3XYPH@572511|Blautia 1.0 186801|Clostridia 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane 1.0 secA 1.0 - 1.0 - 1.0 ko:K03070 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 1.0 - 1.0 - 1.0 Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW 1.0 - 1.0 - 1.0 GT41 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 722558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GGRDDVVDFVK MGYG000000164_01756 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,27JFG@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 2219265 1339177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1198896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270779 0 0 0 0 0 0 0 0 0 0 0 0 276886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243869 0 0 0 0 0 0 0 0 546753 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GIIHFAASK MGYG000004797_00724;MGYG000004757_00891;MGYG000003693_02823;MGYG000001750_00316;MGYG000001364_01807;MGYG000002478_04317;MGYG000004464_00098;MGYG000000243_00999 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,2FMV2@200643|Bacteroidia,4AMM1@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family 0.875 galE 1.0 - 1.0 5.1.3.2 1.0 ko:K01784 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00361,M00362,M00632 1.0 R00291,R02984 1.0 RC00289 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 UDP-glucose 4-epimerase. uridine diphospho-galactose-4-epimerase. Also acts on UDP-2-deoxyglucose. UDP-alpha-D-glucose = UDP-alpha-D-galactose. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1214645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GKSYYFDTDGK MGYG000000255_01008 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1568002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GLSRPLIGMHFFNPADR MGYG000001300_00294 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GLVGSIEAADAMVK MGYG000000150_00816;MGYG000001311_03739;MGYG000001564_02266;MGYG000000179_01371;MGYG000000233_02830;MGYG000001171_01490;MGYG000001714_00561;MGYG000000198_01506;MGYG000001367_03226;MGYG000003589_02226;MGYG000002938_00022;MGYG000000150_00833 domain d__Bacteria 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 0.5833333333333334 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 0.6666666666666666 NPD7_940 0.6666666666666666 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 722652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1294065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GNADAALAAK MGYG000001255_00192 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_F|m__MGYG000001255 1.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3WG9R@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 aconitate hydratase 1.0 acnA 1.0 - 1.0 4.2.1.3 1.0 ko:K01681 1.0 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 1.0 M00009,M00010,M00012,M00173,M00740 1.0 R01324,R01325,R01900 1.0 RC00497,RC00498,RC00618 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aconitase,Aconitase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aconitate hydratase. citrate hydro-lyase. Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate.-!-The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate.-!-cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate.-!-Formerly EC 4.2.1.4. citrate = D-threo-isocitrate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Citrate cycle (TCA cycle);Glyoxylate and dicarboxylate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2190817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GNGAILITTK MGYG000000196_00769 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4AWE8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2356720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GQVYVLSKEEGGR MGYG000004526_00639;MGYG000001616_00520 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,2N71Q@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GTDVMIAGK MGYG000003423_00948 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__W3P20-009|g__W3P20-009|s__W3P20-009 sp900766825|m__MGYG000003423 1.0 COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,2FPWZ@200643|Bacteroidia,3XJY8@558415|Marinilabiliaceae 1.0 976|Bacteroidetes 1.0 H 1.0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 1.0 ahcY 1.0 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 1.0 3.3.1.1 1.0 ko:K01251 1.0 ko00270,ko01100,map00270,map01100 1.0 M00035 1.0 R00192,R04936 1.0 RC00056,RC00069,RC01161,RC01243 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 1.0 - 1.0 - 1.0 - 1.0 AdoHcyase,AdoHcyase_NAD,Flavokinase,NUDIX 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adenosylhomocysteinase. SAHase. The enzyme contains one tightly bound NAD(+) per subunit.-!-This appears to bring about a transient oxidation at C-3' of the 5'-deoxyadenosine residue, thus labilizing the thioether bond, cf. EC 5.5.1.4.-!-Formerly EC 3.3.1.1. H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism;Metabolic pathways 1.0 none 1.0 0 1319986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1280457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 879821 0 0 0 -(Methyl)GVAGTIFVHK MGYG000000179_02177;MGYG000000198_04018;MGYG000000164_02351;MGYG000001311_02985 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia 0.5 186801|Clostridia 1.0 G 1.0 Dihydroxyacetone kinase 0.5 dhaK 1.0 - 1.0 2.7.1.121 1.0 ko:K05878 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak1,SDH_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways 1.0 none 1.0 1419431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)GVDSSVFETLR MGYG000003351_00939 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900765785|m__MGYG000003351 1.0 COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,2FMYF@200643|Bacteroidia,4AMJJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 purB 1.0 - 1.0 4.3.2.2 1.0 ko:K01756 1.0 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 1.0 M00048,M00049 1.0 R01083,R04559 1.0 RC00379,RC00444,RC00445 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADSL_C,ASL_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adenylosuccinate lyase. succino AMP-lyase. Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole. (1) N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate. (2) (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamide + fumarate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 483643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)IGTVGDAVSYIEANAK MGYG000002478_01408;MGYG000002560_00500;MGYG000004797_04291;MGYG000003282_01546 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,2FTWG@200643|Bacteroidia,4ARQA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Carrier of the growing fatty acid chain in fatty acid biosynthesis 1.0 acpP 1.0 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 1.0 - 1.0 ko:K02078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001 1.0 - 1.0 - 1.0 - 1.0 PP-binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19601458 11436891 0 0 0 0 0 0 0 4956677 0 0 0 0 0 0 0 0 0 0 0 334014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31492160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6563968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)IQALADAAR MGYG000000150_02059;MGYG000000242_01807;MGYG000002602_00833;MGYG000000278_00929;MGYG000000967_00332;MGYG000000077_02594;MGYG000001714_01312;MGYG000001564_01915;MGYG000000262_00162;MGYG000004869_03336;MGYG000001526_00290;MGYG000004547_00257;MGYG000001507_06267 domain d__Bacteria 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,2206V@1506553|Lachnoclostridium 0.38461538461538464 186801|Clostridia 0.8461538461538461 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 0.8461538461538461 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4759521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)IVGLYSAPAGSTVLIDR MGYG000000557_01986 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__|m__MGYG000000557 1.0 COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,4PRNS@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 E 1.0 Orn/Lys/Arg decarboxylase, N-terminal domain 1.0 adiA 1.0 - 1.0 4.1.1.18,4.1.1.19 1.0 ko:K01582,ko:K01584 1.0 ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110 1.0 M00133 1.0 R00462,R00566 1.0 RC00299 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine decarboxylase. | arginine decarboxylase. L-lysine carboxy-lyase. | L-arginine carboxy-lyase. Also acts on 5'-hydroxy-L-lysine. H(+) + L-lysine = cadaverine + CO2. | H(+) + L-arginine = agmatine + CO2. 1.0 1.0 1.0 1.0 Metabolic pathways;Arginine and proline metabolism;Biosynthesis of secondary metabolites;Lysine degradation;Tropane, piperidine and pyridine alkaloid biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)KAEDLKELYVLPENDLK MGYG000000198_05929 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,21ZAM@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 5239375 1476378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3607914 0 3624455 0 0 0 0 0 0 5605543 0 0 4807045 0 0 0 0 0 0 4730457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2718948 0 3092325 0 4969809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2176641 0 0 0 0 0 0 0 0 1858559 0 0 4856938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)KGDLYGVDLGGDVIPLPK MGYG000003166_00269 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539885|m__MGYG000003166 1.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGC7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 P 1.0 Belongs to the ABC transporter superfamily 1.0 - 1.0 - 1.0 - 1.0 ko:K10112 1.0 ko02010,map02010 1.0 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1 1.0 - 1.0 - 1.0 ABC_tran,TOBE,TOBE_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)KYSPQEISAMILQK MGYG000003012_00270;MGYG000000690_01090;MGYG000002276_02250;MGYG000001551_00080;MGYG000004697_01220;MGYG000000175_03865;MGYG000001615_03019;MGYG000000200_01023;MGYG000000002_00433;MGYG000001714_02275;MGYG000000249_01105;MGYG000000181_00382;MGYG000004869_03374;MGYG000000171_01795;MGYG000002126_00706;MGYG000001689_04245;MGYG000000262_01374;MGYG000002772_01367;MGYG000001310_00050;MGYG000000038_00915;MGYG000001315_00535;MGYG000004733_01142;MGYG000000142_01918;MGYG000003427_02364;MGYG000004740_00081;MGYG000000077_00522;MGYG000000202_02200;MGYG000000251_02358;MGYG000002279_01669;MGYG000003335_02400;MGYG000000164_00503;MGYG000003165_00617;MGYG000000562_02511;MGYG000004879_00274;MGYG000004296_02335;MGYG000002974_00091;MGYG000003821_01669;MGYG000004547_01722;MGYG000000287_03181;MGYG000001374_00251;MGYG000001303_03339;MGYG000000133_02344;MGYG000004762_01166;MGYG000002234_00982 domain d__Bacteria 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.5227272727272727 186801|Clostridia 0.9772727272727273 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 0.9772727272727273 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)LDNLVLR MGYG000002469_00977;MGYG000001292_01716 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0406@1|root,COG0406@2|Bacteria,2GK2I@201174|Actinobacteria,4CZH2@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Phosphoglycerate mutase family 1.0 - 1.0 - 1.0 5.4.2.12 1.0 ko:K15634 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 His_Phos_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)LGNPSLTQVEEK MGYG000002057_00001 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Dysosmobacter|s__Dysosmobacter sp001916835|m__MGYG000002057 1.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia,2N74S@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Methionine gamma-lyase 1.0 megL 1.0 - 1.0 2.5.1.48,4.4.1.11 1.0 ko:K01739,ko:K01761 1.0 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 1.0 M00017 1.0 R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946 1.0 RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 cystathionine gamma-synthase. | methionine gamma-lyase. O-succinyl-L-homoserine succinate-lyase (adding cysteine). | methionine lyase. Also reacts with H2S and methanethiol as replacing agents, producing homocysteine and methionine, respectively.-!-In the absence of thiol, can also catalyze beta,gamma-elimination to form 2-oxobutanoate, succinate and ammonia.-!-Formerly EC 4.2.99.9. | The enzyme cleaves a carbon-sulfur bond, releasing methanethiol and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form 2-oxobutanoate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-The enzyme is involved in L-methionine catabolism. L-cysteine + O-succinyl-L-homoserine = H(+) + L,L-cystathionine + succinate. | H2O + L-methionine = 2-oxobutanoate + methanethiol + NH4(+). 1.0 1.0 1.0 1.0 Sulfur metabolism;Metabolic pathways;Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Selenocompound metabolism;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3187953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)LSSANSINIGR MGYG000001617_01152;MGYG000000255_01003;MGYG000003013_01480;MGYG000004087_00427 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,21ZGH@1506553|Lachnoclostridium 0.75 186801|Clostridia 1.0 E 1.0 Threonine synthase 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 892291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502650 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)LSTTITGLEMFRK MGYG000003166_01350;MGYG000000022_02283;MGYG000002224_01123;MGYG000002040_01212;MGYG000002272_01482 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125739 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)MMQPQIKPVDEHSAGDIIAR MGYG000002494_03452;MGYG000002477_02737 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,3XM8Y@561|Escherichia 0.5 1236|Gammaproteobacteria 1.0 J 0.5 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) 1.0 cheZ 1.0 GO:0001539,GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032991,GO:0036211,GO:0040011,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0097588,GO:0098561,GO:0140096,GO:1901564 1.0 - 1.0 ko:K03414 1.0 ko02030,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheZ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1677556 0 0 0 0 0 0 2258509 0 0 0 0 0 0 2185367 0 1954201 0 2801449 2499772 0 1737992 1650411 0 0 0 0 2027774 0 0 1641889 0 0 0 0 1330429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)MNKSDLISAMAAEAQMSK MGYG000003312_02172;MGYG000000013_02349 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia,4ARQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 1102668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1550675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)NDGASIAEVTGR MGYG000002223_00691;MGYG000002619_01468;MGYG000002651_02042;MGYG000000022_01688;MGYG000002641_02245 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,3WHDM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 T 1.0 Psort location CytoplasmicMembrane, score 1.0 cstA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CstA,CstA_5TM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 2661035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8873287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)NDGVVLVTTK MGYG000000236_04054 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AKMU@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 923772 0 0 0 0 0 0 0 0 0 0 1034961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)NGATVSGPVPLPTKK MGYG000000251_01832 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter saccharivorans|m__MGYG000000251 1.0 COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,2N66W@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 KLT 1.0 Protein kinase domain 1.0 prkC 1.0 - 1.0 2.7.11.1 1.0 ko:K12132 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01001 1.0 - 1.0 - 1.0 - 1.0 PASTA,PBP1_TM,Pkinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 non-specific serine/threonine protein kinase. threonine-specific protein kinase. This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.-!-Formerly EC 2.7.1.37 and EC 2.7.1.70. (1) ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]. (2) ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl- [protein]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1708104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)NGLPSLFDFEKK MGYG000003899_01005 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539945|m__MGYG000003899 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 1499073 0 0 0 0 0 0 0 0 1283104 0 0 0 0 0 0 0 0 1495891 0 0 0 0 0 0 1110585 0 0 0 0 1148011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)NLDYDLIITGR MGYG000000077_02468;MGYG000000080_01476;MGYG000001637_02230;MGYG000000087_01268;MGYG000001777_01059;MGYG000002067_00419;MGYG000002445_02276;MGYG000002528_02668;MGYG000000028_00944;MGYG000000271_02101;MGYG000000404_01798;MGYG000003694_00880;MGYG000000398_00614;MGYG000000255_01557;MGYG000002492_00660;MGYG000000154_01281;MGYG000000356_02130;MGYG000002517_00543;MGYG000004762_01002;MGYG000000262_02235;MGYG000000217_01341 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.5714285714285714 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.5714285714285714 etfB 1.0 - 0.9047619047619048 - 0.8571428571428571 ko:K03521 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.8571428571428571 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 562191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 533296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)NLFKDEVR MGYG000003166_01352;MGYG000000251_01432;MGYG000002934_01864;MGYG000001255_01096;MGYG000002223_00095;MGYG000000389_01945;MGYG000002545_00612;MGYG000003899_01640;MGYG000002492_00550;MGYG000002641_00286;MGYG000002517_02553;MGYG000002274_01246;MGYG000000271_01306;MGYG000000133_02533;MGYG000000022_02285;MGYG000001300_00155;MGYG000002619_02218;MGYG000001319_01195;MGYG000002670_00532;MGYG000000398_02147;MGYG000000187_01380;MGYG000001637_01668;MGYG000002272_01480;MGYG000001814_03139;MGYG000000489_01853;MGYG000004548_02048;MGYG000003422_00594 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3WGXK@541000|Ruminococcaceae 0.4074074074074074 186801|Clostridia 0.9629629629629629 F 1.0 Catalyzes the synthesis of GMP from XMP 1.0 guaA 1.0 - 0.9629629629629629 6.3.5.2 0.9629629629629629 ko:K01951 0.9629629629629629 ko00230,ko00983,ko01100,map00230,map00983,map01100 1.0 M00050 1.0 R01230,R01231,R08244 1.0 RC00010,RC00204 1.0 ko00000,ko00001,ko00002,ko01000,ko01002 0.9629629629629629 - 1.0 - 1.0 - 0.9629629629629629 ATP_bind_3,GATase,GMP_synt_C,NAD_synthase,ThiI,tRNA_Me_trans 0.9629629629629629 - 1.0 - 1.0 - 1.0 - 1.0 GMP synthase (glutamine-hydrolyzing). GMP synthetase (glutamine-hydrolyzing). Involved in the de novo biosynthesis of guanosine nucleotides.-!-An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain.-!-The enzyme can catalyze the second reaction alone in the presence of ammonia.-!-Formerly EC 6.3.4.1. ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate. 0.9629629629629629 0.9629629629629629 0.9629629629629629 0.9629629629629629 Purine metabolism;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1163280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1202430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1046268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 741157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1798235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)NNLGELAYQAGK MGYG000004763_02569 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 4957033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)NPVQVNEAAGFVVNR MGYG000000022_01323;MGYG000002040_01716 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1207030 0 0 0 0 703790 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)NVTADSIAK MGYG000002057_01748 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Dysosmobacter|s__Dysosmobacter sp001916835|m__MGYG000002057 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,2N6SP@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 3391224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1057984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)NVVLLFQK MGYG000001567_01136 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__|m__MGYG000001567 1.0 COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4CUPQ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline 1.0 argF 1.0 - 1.0 2.1.3.3 1.0 ko:K00611 1.0 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 1.0 M00029,M00844 1.0 R01398 1.0 RC00096 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ornithine carbamoyltransferase. OTCase. The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively. carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1002873 0 2079990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 62986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)NYANQTLLR MGYG000003367_00149;MGYG000004763_01978;MGYG000002082_00368;MGYG000003493_01296;MGYG000000043_00075;MGYG000002218_00065;MGYG000003363_00419;MGYG000001306_00718;MGYG000003279_02442;MGYG000000355_00809;MGYG000000003_00510;MGYG000001783_00052;MGYG000000273_02673;MGYG000004479_00771;MGYG000001364_00648 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.6 976|Bacteroidetes 1.0 G 1.0 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.6 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1038124 832224 1348645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150682 0 0 -(Methyl)QLLAMTK MGYG000000243_02146 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,2FQ1C@200643|Bacteroidia,4AMBP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family 1.0 mtrC 1.0 - 1.0 - 1.0 ko:K03585 1.0 ko01501,ko01503,map01501,map01503 1.0 M00646,M00647,M00699,M00718 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 1.0 2.A.6.2,8.A.1.6 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cationic antimicrobial peptide (CAMP) resistance;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)QSVSQYVASVAK MGYG000000179_02938;MGYG000000242_00796 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,21ZJJ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2485816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)SAFPGAIK MGYG000004797_01529 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AWE5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1570210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)SIAQQQNTQFK MGYG000000076_01275;MGYG000003694_00879;MGYG000000280_01471;MGYG000000153_01461;MGYG000000136_00900;MGYG000001637_02229;MGYG000000271_02102;MGYG000004271_00233;MGYG000000389_02149;MGYG000001186_01721;MGYG000002492_00659;MGYG000002670_01509;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.6923076923076923 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 0.6923076923076923 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 6179705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1057361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3293943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)SISIDPEVIKR MGYG000002455_04364 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1155723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)SLEEGQAVSYDLTEGAR MGYG000002989_01533;MGYG000000287_00735;MGYG000000142_02892;MGYG000000031_02446;MGYG000001698_02841;MGYG000001689_05168;MGYG000004869_01115;MGYG000000263_01644;MGYG000000119_01719;MGYG000003147_00139;MGYG000004747_02624;MGYG000001602_00984;MGYG000000216_02459 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 Cold shock protein 1.0 - 1.0 - 1.0 - 1.0 ko:K03704 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 CSD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 465781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)SQQVTDAC(Carbamidomethyl)KK MGYG000004899_01569;MGYG000002323_01973;MGYG000002478_01945;MGYG000000243_02673;MGYG000001313_01946;MGYG000004464_00188;MGYG000003681_00341;MGYG000000098_02497;MGYG000001780_03233;MGYG000002506_00941;MGYG000000222_02644;MGYG000002455_02631 domain d__Bacteria 1.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,4NE85@976|Bacteroidetes,2FNPE@200643|Bacteroidia,4AKTC@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 0.8333333333333334 C 1.0 Catalyzes the reversible hydration of fumarate to (S)- malate 0.8333333333333334 fumB 0.8333333333333334 - 0.8333333333333334 4.2.1.2 1.0 ko:K01676 1.0 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00374 1.0 R01082 1.0 RC00443 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 0.8333333333333334 Fumerase,Fumerase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fumarate hydratase. fumarase. - (S)-malate = fumarate + H2O. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)SREFEPDAPNYTPR MGYG000002835_02584;MGYG000004735_01618;MGYG000000031_02755 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3XZ1G@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 8.87 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP_cyclohyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)SVDVMVK MGYG000000078_01647;MGYG000002528_01864;MGYG000000278_00938;MGYG000003215_00849;MGYG000004055_01475;MGYG000002417_02110;MGYG000003500_00156;MGYG000002559_01476;MGYG000001141_01291;MGYG000001564_01925;MGYG000003786_01019;MGYG000000204_02185;MGYG000001619_00808;MGYG000001793_01089;MGYG000002052_00761;MGYG000000028_01597;MGYG000004879_02709 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,21ZID@1506553|Lachnoclostridium 0.5294117647058824 186801|Clostridia 1.0 J 0.8823529411764706 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 0.6470588235294118 rpsD 0.6470588235294118 - 1.0 - 1.0 ko:K02986 0.6470588235294118 ko03010,map03010 0.8823529411764706 M00178,M00179 0.8823529411764706 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.8823529411764706 - 1.0 - 1.0 - 0.8823529411764706 Ribosomal_S4,S4 0.6470588235294118 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.8823529411764706 none 1.0 3609657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1383354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1764186 0 0 0 0 0 0 0 0 0 0 156719 0 -(Methyl)SVEELIEVVK MGYG000004733_01558 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase delta subunit 1.0 acsD 1.0 - 1.0 2.1.1.245 1.0 ko:K00194 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism;Carbon metabolism 1.0 none 1.0 491780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)SYYFDTDGK MGYG000000255_01008 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 11397768 8195866 0 0 6276071 0 0 0 0 0 0 7404045 0 0 0 0 8674442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12576693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2520831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2551628 0 0 0 0 0 0 0 0 0 0 0 2388006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)TAAILFSK MGYG000004797_02947;MGYG000002478_02940 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379588 0 0 0 0 472782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 68852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)TSEVLIDYR MGYG000004642_00430 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG2998@1|root,COG2998@2|Bacteria,1UI9K@1239|Firmicutes,25EEI@186801|Clostridia,36S90@31979|Clostridiaceae 1.0 2|Bacteria 1.0 H 1.0 Copper amine oxidase N-terminal domain 1.0 - 1.0 - 1.0 - 1.0 ko:K05772 1.0 ko02010,map02010 1.0 M00186 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.6.2,3.A.1.6.4 1.0 - 1.0 - 1.0 CAP,Cu_amine_oxidN1,NHL,PBP_like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2849268 0 0 0 0 1746716 0 0 1039361 2968550 0 1331791 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)TVEQAGMPMR MGYG000001733_00306 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550615|m__MGYG000001733 1.0 COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,247Q7@186801|Clostridia,25V46@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 1.0 - 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00175 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VASIVGR MGYG000002534_00124 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_A|s__Citrobacter_A farmeri|m__MGYG000002534 1.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECSE_1348.ECSE_3895,iJN746.PP_5056 1.0 Metalloenzyme,Phosphodiest,iPGM_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2863217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VASIYYQGLMR MGYG000001378_04234;MGYG000000029_00498;MGYG000000236_01493;MGYG000002281_03613;MGYG000000196_02323;MGYG000001461_03024;MGYG000001345_03404;MGYG000000013_01747;MGYG000003312_00912;MGYG000002549_04269;MGYG000000098_00597;MGYG000000054_02343 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 938430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VAVVADDLAQESR MGYG000004642_00531;MGYG000004285_00367 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670 1.0 COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,36FZP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 2-hydroxyglutaryl-CoA dehydratase, D-component 1.0 - 1.0 - 1.0 1.3.7.8,4.2.1.54 1.0 ko:K04112,ko:K20627 1.0 ko00362,ko00640,ko00643,ko01100,ko01120,ko01220,map00362,map00640,map00643,map01100,map01120,map01220 1.0 M00541 1.0 R02451,R02963 1.0 RC00002,RC00818,RC01839 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HGD-D 1.0 - 1.0 - 1.0 - 1.0 - 1.0 benzoyl-CoA reductase. | lactoyl-CoA dehydratase. - Inactive toward aromatic acids that are not CoA esters but will also catalyze the reaction: NH3 + acceptor + 2 ADP + 2 phosphate = hydroxylamine + reduced acceptor + 2 ATP + H2O.-!-In the presence of reduced acceptor, but in the absence of oxidizable substrate, the enzyme catalyzes the hydrolysis of ATP to ADP plus phosphate.-!-Formerly EC 1.3.99.15. | A bacterial enzyme that is involved in propanoate fermentation (also known as the acrylate pathway). 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized 2[4Fe-4S]- [ferredoxin] + 2 phosphate = 2 ATP + benzoyl-CoA + 2 H2O + reduced 2[4Fe- 4S]-[ferredoxin]. | (R)-lactoyl-CoA = acryloyl-CoA + H2O. 1.0 1.0 1.0 1.0 Benzoate degradation;Metabolic pathways;Styrene degradation;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 621293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1612563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VDEGLDVVER MGYG000001787_02427;MGYG000000042_00775 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32729701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VEAALEKGDVEGAK MGYG000004479_00625;MGYG000001306_01045;MGYG000000781_01742;MGYG000001835_01871;MGYG000001783_00207 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2145075 1707510 0 3239464 0 0 0 0 1988674 1660459 0 0 2088458 0 0 0 0 0 601224 0 1201084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VEGDSVIVQR MGYG000000997_00555;MGYG000001315_01867;MGYG000004762_01002;MGYG000000262_02235 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.5 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.5 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6619098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8498000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VEISNTSHPFYTGK MGYG000000696_00259;MGYG000002438_02631;MGYG000001489_00349;MGYG000004848_01257 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,2FTUG@200643|Bacteroidia,22YDW@171551|Porphyromonadaceae 0.75 976|Bacteroidetes 1.0 J 1.0 50S ribosomal protein L31 type B 1.0 rpmE2 1.0 - 1.0 - 1.0 ko:K02909 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L31 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2682612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VEYGEAAFYGPK MGYG000002675_01264;MGYG000003693_02322;MGYG000000105_00777;MGYG000000224_02651;MGYG000001313_02731;MGYG000002109_00674;MGYG000003539_00169;MGYG000004241_01257;MGYG000000053_01342;MGYG000002478_04502;MGYG000003681_01663;MGYG000004797_02455;MGYG000001789_02626;MGYG000000462_01070;MGYG000003554_00847;MGYG000004763_00464;MGYG000002171_01299;MGYG000001661_02959;MGYG000004464_01888;MGYG000003992_01259 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,2FMAU@200643|Bacteroidia,4AMPD@815|Bacteroidaceae 0.55 976|Bacteroidetes 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 445782 0 0 0 0 888080 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VFATYTQEQVDK MGYG000000278_03205 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA3402|s__UBA3402 sp003478355|m__MGYG000000278 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,36DKD@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1411174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VFSINGEIKPGVR MGYG000004893_00612 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A sp900555485|m__MGYG000004893 1.0 COG3055@1|root,COG3055@2|Bacteria,378BK@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 S 1.0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Kelch_1,Kelch_4,Kelch_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1375413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VFVHHENR MGYG000001783_01513 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900551065|m__MGYG000001783 1.0 COG3408@1|root,COG3408@2|Bacteria,4NF09@976|Bacteroidetes,2FMEX@200643|Bacteroidia,4ANWK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 glycogen debranching enzyme, archaeal type 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GDE_C,GDE_N 1.0 - 1.0 GH133 1.0 GH133 1.0 GH133 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 852464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1185696 0 0 0 0 2065168 0 0 0 0 1927694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 926407 0 0 0 0 854538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1031130 0 0 0 0 1542802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VGDDVPTVQNPEYFR MGYG000001783_01377;MGYG000000043_01665 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,2FM2Z@200643|Bacteroidia,4AN6Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate 1.0 purL 1.0 - 1.0 6.3.5.3 1.0 ko:K01952 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04463 1.0 RC00010,RC01160 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C,GATase_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylformylglycinamidine synthase. phosphoribosylformylglycinamidine synthetase. - ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D- ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D- ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1540251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VGGYGEAVASFK MGYG000003693_01537 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG2433@1|root,COG2433@2|Bacteria,4PKWF@976|Bacteroidetes,2G069@200643|Bacteroidia,4AKR0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Porin_O_P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809301 0 0 0 0 1468833 0 0 0 0 854045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VGIGPGSIC(Carbamidomethyl)TTR MGYG000000271_00603;MGYG000001558_01970;MGYG000002036_00721;MGYG000004513_02444;MGYG000000213_01314;MGYG000000348_01357;MGYG000000433_01485;MGYG000004271_01872;MGYG000001431_00382;MGYG000000204_01913;MGYG000002164_00434;MGYG000004735_02781;MGYG000002802_01985;MGYG000000146_01483;MGYG000002992_01076;MGYG000001654_00568;MGYG000003279_02037;MGYG000004468_00808;MGYG000000164_00891;MGYG000000205_01225;MGYG000001489_02595;MGYG000000170_02064;MGYG000000142_02314;MGYG000003446_00567;MGYG000004848_01417;MGYG000002721_01246;MGYG000003984_01817;MGYG000004899_03971;MGYG000003164_01607;MGYG000001681_02186;MGYG000003825_01286;MGYG000000263_02824;MGYG000000362_00934;MGYG000000280_00135;MGYG000001237_00306;MGYG000001559_01603;MGYG000000354_00044;MGYG000002515_00630;MGYG000004495_02116;MGYG000000273_02631;MGYG000000262_01414;MGYG000001306_01130;MGYG000001623_01024;MGYG000000412_01379;MGYG000001571_02994;MGYG000004847_02037;MGYG000003470_00956;MGYG000003149_00433;MGYG000001732_00933;MGYG000004006_00824;MGYG000003783_01872;MGYG000001645_00506;MGYG000002080_00704;MGYG000000080_01161;MGYG000000048_02015;MGYG000004797_02827;MGYG000000013_03187;MGYG000001432_00165;MGYG000003142_02362;MGYG000003493_00600;MGYG000004738_00436;MGYG000000196_04055;MGYG000002293_02133;MGYG000001370_01971;MGYG000002534_03593;MGYG000002535_01039;MGYG000002438_02195;MGYG000003391_01338;MGYG000000133_00306;MGYG000004658_02026;MGYG000000138_02900;MGYG000003390_00955;MGYG000004667_03662;MGYG000000356_01714;MGYG000003697_01312;MGYG000002836_02134;MGYG000004642_00172;MGYG000003694_03060;MGYG000000198_00495;MGYG000001611_01647;MGYG000002506_02025;MGYG000001359_00988;MGYG000003782.1_00452;MGYG000002494_04050;MGYG000004285_01802;MGYG000001637_01052;MGYG000002713_01239;MGYG000002737_00135;MGYG000002937_01780;MGYG000000092_00381;MGYG000001485_02667;MGYG000003236_01758;MGYG000003282_00251;MGYG000001630_01208;MGYG000004087_02343;MGYG000002067_00750;MGYG000001643_01399;MGYG000004464_01403;MGYG000002685_00288;MGYG000002901_00218;MGYG000004704_01124;MGYG000002997_01145;MGYG000000087_02531;MGYG000000562_02421;MGYG000003858_02319;MGYG000003162_00158;MGYG000001407_01210;MGYG000003022_00656;MGYG000001367_02921;MGYG000004517_00100;MGYG000004879_00512;MGYG000003338_02530;MGYG000002881_00044;MGYG000001313_02959;MGYG000002492_02315;MGYG000000489_00932;MGYG000003486_02497;MGYG000003202_01530;MGYG000002834_01472;MGYG000004850_00007;MGYG000004250_01264;MGYG000001327_01268;MGYG000000233_01272;MGYG000001193_00608;MGYG000003922_01814;MGYG000004727_00678;MGYG000001315_00701;MGYG000001781_01698;MGYG000000074_01340;MGYG000000187_01407;MGYG000002670_00089;MGYG000000437_01226;MGYG000002574_00994;MGYG000000243_00691;MGYG000004869_03402;MGYG000003549_00730;MGYG000004884_01768;MGYG000000989_02246;MGYG000001314_02149;MGYG000004785_01919;MGYG000000735_00745;MGYG000003868_00445;MGYG000000002_02500;MGYG000004828_01108;MGYG000002985_01150;MGYG000002960_01699;MGYG000004471_01025;MGYG000000374_01230;MGYG000003693_00994;MGYG000001056_01201;MGYG000000171_02641;MGYG000001423_03191;MGYG000000701_01634;MGYG000000003_02085;MGYG000003662_00787;MGYG000001701_00556;MGYG000002517_01047;MGYG000001346_00627;MGYG000000212_00040;MGYG000002485_02170;MGYG000001319_00739;MGYG000004851_00152;MGYG000000136_01100;MGYG000002966_01598;MGYG000002469_01587;MGYG000002895_00318;MGYG000003365.1_02647;MGYG000000089_02238;MGYG000000347_01341;MGYG000000215_00958;MGYG000001186_00833;MGYG000003352_01125;MGYG000000127_02910;MGYG000000206_01855;MGYG000004769_00915;MGYG000002963_04223;MGYG000001220_00502;MGYG000004740_01385;MGYG000001685_01145;MGYG000002905_02028;MGYG000002247_00883;MGYG000001412_04889;MGYG000001338_00214;MGYG000000301_00957;MGYG000001477_00304;MGYG000001748_02097;MGYG000000252_03031;MGYG000002478_00464;MGYG000003412_00366;MGYG000000098_03787;MGYG000002279_00396;MGYG000000077_00487;MGYG000000251_01328;MGYG000002298_01715;MGYG000003313_01965;MGYG000002835_00811;MGYG000003116_00649;MGYG000001219_01350;MGYG000003366_01162;MGYG000001787_00508;MGYG000003695_02134;MGYG000001395_02742;MGYG000001507_06410;MGYG000004893_01198 life d__Bacteria 0.9951 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia 0.08823529411764706 186801|Clostridia 0.5294117647058824 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 0.9901960784313726 guaB 1.0 - 0.8872549019607843 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 0.9362745098039216 CBS,IMPDH,NMO 0.6176470588235294 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1242659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 964845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VGNTLSESGTVSR MGYG000000196_00016;MGYG000004757_01252;MGYG000002281_00884;MGYG000000044_00029;MGYG000002478_00412;MGYG000003539_00592;MGYG000000243_00646;MGYG000002033_02736;MGYG000002560_02783;MGYG000000215_00870;MGYG000002549_03470;MGYG000004474_01037;MGYG000002171_01765;MGYG000004797_03414;MGYG000001378_02628;MGYG000003312_02930 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1208@1|root,COG1208@2|Bacteria,4PKJR@976|Bacteroidetes,2G07F@200643|Bacteroidia,4AKG8@815|Bacteroidaceae 0.4375 976|Bacteroidetes 1.0 JM 0.875 COG NOG09722 non supervised orthologous group 0.875 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NTP_transf_3,NTP_transferase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 887284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VIC(Carbamidomethyl)ENPK MGYG000003977_00980;MGYG000002926_00512;MGYG000004718_00086;MGYG000003160_00099;MGYG000001623_00884;MGYG000001464_01348;MGYG000004727_00030;MGYG000000365_01086;MGYG000003219_00818;MGYG000001500_00907;MGYG000003577_01703;MGYG000004810_00893;MGYG000001654_01669;MGYG000004854_01553;MGYG000000071_01854;MGYG000003581_01723;MGYG000004769_00461;MGYG000001460_03688;MGYG000004863_01347;MGYG000000369_01203;MGYG000004893_02156;MGYG000002079_00954;MGYG000001739_00922;MGYG000002139_01167;MGYG000004482_01012;MGYG000002993_00638;MGYG000004715_01204;MGYG000001601_01043;MGYG000003453_00403;MGYG000000405_00856;MGYG000002791_00834;MGYG000001646_00003;MGYG000004729_00728;MGYG000001470_03696;MGYG000004642_00876;MGYG000001746_00300;MGYG000000173_00321;MGYG000001563_00766;MGYG000004453_01158;MGYG000002715_01097;MGYG000000129_01145;MGYG000002702_01376;MGYG000000773_00999;MGYG000002707_00988;MGYG000001635_01410;MGYG000000258_00306;MGYG000001508_00059;MGYG000000435_00508;MGYG000003468_00750;MGYG000004249_00005;MGYG000002994_01290;MGYG000002964_01092;MGYG000000392_01436;MGYG000001405_04496;MGYG000000316_00896;MGYG000001732_00086;MGYG000001712_00145;MGYG000003484_01829;MGYG000003819_01183;MGYG000002716_01471;MGYG000004306_00025;MGYG000001756_01043;MGYG000004894_00054;MGYG000004809_00843;MGYG000000408_01127;MGYG000001488_02393;MGYG000002685_01383;MGYG000002485_02435;MGYG000000367_00545;MGYG000000477_01598;MGYG000003116_00454;MGYG000004784_00611;MGYG000000036_00601;MGYG000002057_00258;MGYG000001191_00894;MGYG000001626_01874;MGYG000002959_00707;MGYG000003465_00819;MGYG000004804_01241;MGYG000001702_03646;MGYG000001647_01148;MGYG000001474_01367;MGYG000004760_01483;MGYG000001326_01426;MGYG000001424_01384;MGYG000001913_00789;MGYG000002251_00158;MGYG000004517_01000;MGYG000001729_00295;MGYG000000182_00560;MGYG000001356_01792;MGYG000001238_00461;MGYG000000423_01045;MGYG000003538_00588;MGYG000002795_00391;MGYG000002848_00835;MGYG000003858_01271;MGYG000001577_00625;MGYG000001400_03640;MGYG000000493_00066;MGYG000000421_00578;MGYG000001697_01855;MGYG000001514_00066;MGYG000003871_00382;MGYG000001225_00112;MGYG000001553_00956;MGYG000000395_00100;MGYG000000919_01842;MGYG000002084_00612;MGYG000000377_01239;MGYG000002753_00096;MGYG000000374_00158;MGYG000000130_00521;MGYG000004700_01644;MGYG000000234_02029;MGYG000004565_00386;MGYG000001618_01418;MGYG000000099_02376;MGYG000000989_00131;MGYG000002659_00433;MGYG000004276_01064;MGYG000000385_00638;MGYG000002235_00892;MGYG000002105_00216;MGYG000004216_00457;MGYG000000073_01954;MGYG000004471_01172;MGYG000004628_02064;MGYG000004613_01552;MGYG000003510_00355;MGYG000001762_00997;MGYG000001507_06276;MGYG000000953_00554;MGYG000003961_00928;MGYG000003428_01084;MGYG000000910_01044;MGYG000000463_00767;MGYG000002953_00616;MGYG000001754_01550;MGYG000000177_02184;MGYG000001502_00387;MGYG000000121_02218;MGYG000004845_01930;MGYG000002042_01077;MGYG000000383_00908;MGYG000002720_00257;MGYG000002159_00236;MGYG000002903_00732;MGYG000000157_01118;MGYG000002067_01291;MGYG000002938_02179;MGYG000003307_01071;MGYG000002854_00085;MGYG000004502_01050;MGYG000000134_01732;MGYG000001477_00042;MGYG000002727_01961;MGYG000004526_00986;MGYG000002156_01375;MGYG000000413_00087;MGYG000004600_01297;MGYG000003153_00563;MGYG000000334_01933;MGYG000002315_01067;MGYG000004828_01829;MGYG000002026_01331;MGYG000004196_00613;MGYG000001365_00981;MGYG000000375_00837;MGYG000002857_00955;MGYG000002934_00498;MGYG000004252_00086 domain d__Bacteria 1.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,269B1@186813|unclassified Clostridiales 0.29651162790697677 186801|Clostridia 0.7848837209302325 J 0.9127906976744186 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex 0.5348837209302325 infA 0.5348837209302325 - 0.9941860465116279 - 1.0 ko:K02518 0.5348837209302325 - 0.6686046511627907 - 0.6686046511627907 - 1.0 - 1.0 ko00000,ko03012 0.5348837209302325 - 1.0 - 1.0 - 1.0 eIF-1a 0.5348837209302325 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.6686046511627907 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6137540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VILPDPVFNDQK MGYG000000029_02786;MGYG000000236_01790;MGYG000002549_02928;MGYG000002293_00508;MGYG000001306_02657;MGYG000003697_01471;MGYG000000196_03986;MGYG000002281_02278;MGYG000002455_03896;MGYG000001337_03892;MGYG000002834_00437;MGYG000000243_01974;MGYG000002603_01770;MGYG000003312_02994;MGYG000000013_02239;MGYG000001787_02681;MGYG000000098_02005 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 0.8235294117647058 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032740 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VITSFAGLR MGYG000002298_00538;MGYG000000038_01495;MGYG000000280_01802;MGYG000000404_00180;MGYG000001619_01503;MGYG000002312_03079;MGYG000000171_00187;MGYG000000255_01681;MGYG000000164_01752;MGYG000000271_03444;MGYG000001683_00852;MGYG000000301_00532;MGYG000002517_00473;MGYG000001311_02981;MGYG000000489_00238;MGYG000000154_01590;MGYG000000142_00484;MGYG000000153_02080;MGYG000000076_01007;MGYG000004087_02481;MGYG000002946_03411;MGYG000000245_01076;MGYG000000031_00359;MGYG000000205_00110;MGYG000002276_00835;MGYG000003074_00570;MGYG000000127_02775;MGYG000000179_02173;MGYG000002279_02522;MGYG000001315_01114;MGYG000004271_01228;MGYG000000212_00378;MGYG000000198_04022 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 0.30303030303030304 186801|Clostridia 1.0 S 0.6060606060606061 FAD dependent oxidoreductase 0.5151515151515151 - 0.9090909090909091 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 1174189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VKEVADAAR MGYG000001306_02676;MGYG000002281_02259;MGYG000000236_01771;MGYG000000013_02220;MGYG000002935_01255;MGYG000000196_04005;MGYG000004763_00942;MGYG000004748_03258;MGYG000001461_00420;MGYG000001378_05011;MGYG000002470_01214;MGYG000001337_03873;MGYG000002561_02191;MGYG000001313_00058;MGYG000000054_03874;MGYG000000442_02026;MGYG000000273_00390;MGYG000003693_00209;MGYG000002549_02909;MGYG000004479_01416;MGYG000001345_04715;MGYG000000029_02805;MGYG000000781_00864;MGYG000000042_01075;MGYG000004185_01147;MGYG000001925_01448;MGYG000000105_02020;MGYG000002933_02445;MGYG000003681_02067 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia,4AQZ3@815|Bacteroidaceae 0.9655172413793104 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1950474 0 0 0 0 0 0 0 0 0 0 0 0 0 1564310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VKGEPLTDFIGTTR MGYG000000196_02501;MGYG000002549_04620 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,2FNZ4@200643|Bacteroidia,4ANT4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the LDH MDH superfamily 1.0 mdh 1.0 - 1.0 1.1.1.37 1.0 ko:K00024 1.0 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 1.0 R00342,R07136 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ldh_1_C,Ldh_1_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 malate dehydrogenase. malic dehydrogenase. Also oxidizes some other 2-hydroxydicarboxylic acids. (S)-malate + NAD(+) = H(+) + NADH + oxaloacetate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Citrate cycle (TCA cycle);Glyoxylate and dicarboxylate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Cysteine and methionine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 719009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 197553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VLAEFAK MGYG000000233_00505;MGYG000000205_00362 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,21ZWI@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1166509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VLIMPGDNSSVPTMR MGYG000002720_00601 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG1879@1|root,COG1879@2|Bacteria,1UE0M@1239|Firmicutes,24C7Y@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system, periplasmic 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1960455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VLKLETFR MGYG000001599_02035;MGYG000000224_00262;MGYG000003681_00233;MGYG000001661_00812 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG3717@1|root,COG3717@2|Bacteria,4NDUV@976|Bacteroidetes,2FMP5@200643|Bacteroidia,4AM3B@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate 1.0 kduI 1.0 - 1.0 5.3.1.17 1.0 ko:K01815 1.0 ko00040,map00040 1.0 - 1.0 R04383 1.0 RC00541 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 KduI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 5-dehydro-4-deoxy-D-glucuronate isomerase. 5-keto-4-deoxyuronate isomerase. The enzyme is involved in the degradation of polygalacturonate, a later stage in the degradation of pectin by many microorganisms. 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VLPGIAAIR MGYG000001835_00603 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp000432735|m__MGYG000001835 1.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NIEK@976|Bacteroidetes,2FMAP@200643|Bacteroidia,4AKI4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 Psort location CytoplasmicMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1071096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VLPGVAAIKGE MGYG000000243_00781;MGYG000003420_00378;MGYG000004703_01936;MGYG000001447_00495;MGYG000002478_02340 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 0.6 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 0.6 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 3704927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4267523 0 0 0 0 0 0 0 0 3276040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3771420 5841969 3650338 0 0 0 0 0 3263475 9524499 0 0 8552934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VLVATEKPFAK MGYG000003511_00832;MGYG000000029_02971;MGYG000003312_01933;MGYG000000013_04188;MGYG000001306_01782;MGYG000001415_00202;MGYG000001750_00741;MGYG000000196_03462;MGYG000001787_00809;MGYG000003693_03256;MGYG000002549_01443;MGYG000001337_02575;MGYG000001835_00780 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,4AKZ7@815|Bacteroidaceae 0.46153846153846156 976|Bacteroidetes 1.0 C 0.46153846153846156 Conserved protein 0.46153846153846156 - 0.6153846153846154 - 1.0 1.1.1.399,1.1.1.95 0.5384615384615384 ko:K00058 0.5384615384615384 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 0.5384615384615384 M00020 0.5384615384615384 R01513 0.5384615384615384 RC00031 0.5384615384615384 ko00000,ko00001,ko00002,ko01000,ko04147 0.5384615384615384 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 0.5384615384615384 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 0.5384615384615384 0.5384615384615384 0.5384615384615384 0.5384615384615384 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 0.5384615384615384 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 923989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VNIEFDMPSR MGYG000002478_01480;MGYG000004479_01900;MGYG000000243_01831;MGYG000001787_00130 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,2FMNU@200643|Bacteroidia,4AMJB@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 GTP-binding protein TypA 1.0 typA 1.0 - 1.0 - 1.0 ko:K06207 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VQEFLLNFGK MGYG000004797_02292;MGYG000002478_02024 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FM0V@200643|Bacteroidia,4ANJE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Xaa-His dipeptidase 1.0 pepD_2 1.0 - 1.0 - 1.0 ko:K01270 1.0 ko00480,ko01100,map00480,map01100 1.0 - 1.0 R00899,R04951 1.0 RC00096,RC00141 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Glutathione metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VQFNNAIGPYK MGYG000003693_00515;MGYG000000415_01340;MGYG000001306_03642;MGYG000004464_00132;MGYG000000054_03508;MGYG000002561_00570;MGYG000000245_02477;MGYG000000348_00264;MGYG000002549_04345;MGYG000002218_02291;MGYG000003279_00861;MGYG000003681_00059;MGYG000000222_00649;MGYG000001345_03440;MGYG000000781_00162;MGYG000004879_02390;MGYG000003460_01711;MGYG000002609_02276;MGYG000002721_00727;MGYG000001346_00943;MGYG000002438_00729;MGYG000004797_04374;MGYG000000187_02311;MGYG000000356_00361;MGYG000000003_02629;MGYG000001789_02928;MGYG000002131_02188;MGYG000001666_02162;MGYG000002033_03142;MGYG000002205_00179;MGYG000003367_00479;MGYG000002470_04167;MGYG000002905_01332;MGYG000004757_01061;MGYG000004658_00724;MGYG000004763_01778;MGYG000000354_00366;MGYG000002455_00066;MGYG000002654_00571;MGYG000000243_02155;MGYG000001370_01143;MGYG000004380_02235;MGYG000000138_02030;MGYG000001643_02377;MGYG000002934_01476;MGYG000002517_02750;MGYG000001797_03050;MGYG000001637_01313;MGYG000000489_02253;MGYG000001489_00505;MGYG000000562_02592;MGYG000000196_02411;MGYG000003425_04268;MGYG000002258_01173;MGYG000000076_02271;MGYG000000355_01573;MGYG000002670_01100;MGYG000003133_03072;MGYG000001835_02316;MGYG000000273_02029;MGYG000000236_00923;MGYG000000044_02194;MGYG000002478_00277;MGYG000000174_04135;MGYG000000271_00907;MGYG000004468_00548 domain d__Bacteria 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AMNJ@815|Bacteroidaceae 0.4393939393939394 976|Bacteroidetes 0.696969696969697 C 0.45454545454545453 Belongs to the Glu Leu Phe Val dehydrogenases family 0.7272727272727273 gdh 0.7121212121212122 GO:0005575,GO:0005623,GO:0009986,GO:0044464 0.696969696969697 1.4.1.4 0.7272727272727273 ko:K00262 0.7272727272727273 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 0.7272727272727273 - 0.8787878787878788 R00248 0.7272727272727273 RC00006,RC02799 0.8484848484848485 ko00000,ko00001,ko01000 0.7272727272727273 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.8484848484848485 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.7272727272727273 0.7272727272727273 0.7272727272727273 0.7272727272727273 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.7272727272727273 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507911 0 1448158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VTAEKNPADLK MGYG000001789_00244;MGYG000004479_00217;MGYG000000445_00706;MGYG000001783_01519;MGYG000002933_02039 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 C 0.8 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5698020 0 0 0 4095051 0 0 0 0 0 0 6336316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2616693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VTIQNLEVVR MGYG000002835_00976;MGYG000000280_01267 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,21Z6A@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit 1.0 rplC 1.0 - 1.0 - 1.0 ko:K02906 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 863401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VTYTEPGIKGDTATNTLKPATVESGATVR MGYG000000029_03015;MGYG000000098_03555 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,2FP84@200643|Bacteroidia,4AMEV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1819527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VVC(Carbamidomethyl)EVVSGLVK MGYG000003681_00823 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,2FTJ4@200643|Bacteroidia,4AR0D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 GO:0003674,GO:0003735,GO:0005198 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 DUF4332,HHH_5,Rho_N,Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1846025 0 0 2455068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VVDLIAPYAK MGYG000002777_01079;MGYG000004158_00761;MGYG000000411_00371 genus d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister 1.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4H2IA@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 - 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1082967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VVFTAEDAK MGYG000004726_03204;MGYG000001502_03051 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,268N0@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1488154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 865023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VVGLQTEAPLKR MGYG000002506_00229 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1RM96@1236|Gammaproteobacteria,3XMX2@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 formate C-acetyltransferase activity 1.0 pflB 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECH74115_1262.ECH74115_1064,iECIAI39_1322.ECIAI39_2245,iECSP_1301.ECSP_1007,iECs_1301.ECs0986,iEcSMS35_1347.EcSMS35_2218,iG2583_1286.G2583_1138,iSDY_1059.SDY_2358,iZ_1308.Z1248 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 6097165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5850705 0 0 0 0 0 0 0 0 0 6369675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VVMIEDVTTSGK MGYG000002304_01630;MGYG000001379_01167;MGYG000002298_01629;MGYG000001314_03025;MGYG000002670_00027;MGYG000000141_00942;MGYG000001456.1_02603;MGYG000000119_01768;MGYG000000245_03142;MGYG000000200_01565;MGYG000000325_00864;MGYG000002517_00833;MGYG000000389_01227;MGYG000002596_02168;MGYG000000213_01465;MGYG000000133_02579;MGYG000000212_01799;MGYG000000252_02246;MGYG000001637_02321;MGYG000000489_01061;MGYG000004740_01192;MGYG000000204_00607;MGYG000001338_00074;MGYG000004719_01798;MGYG000000271_01398;MGYG000001528_01833;MGYG000004610_00048;MGYG000000184_02212;MGYG000001714_02809;MGYG000004747_02159;MGYG000002492_02249;MGYG000001602_00995;MGYG000001711_01559 domain d__Bacteria 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 0.5151515151515151 186801|Clostridia 0.9393939393939394 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 0.9393939393939394 ko:K00762 0.9393939393939394 ko00240,ko01100,map00240,map01100 0.9393939393939394 M00051 0.9393939393939394 R01870 0.9393939393939394 RC00611 0.9393939393939394 ko00000,ko00001,ko00002,ko01000 0.9393939393939394 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 0.9393939393939394 0.9393939393939394 0.9393939393939394 0.9393939393939394 Metabolic pathways;Pyrimidine metabolism 0.9393939393939394 none 1.0 1423685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1087844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1971194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350163 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VVSWYDNEFGYSNR MGYG000001508_01079 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Bacillales_D|f__Halobacillaceae|g__Thalassobacillus|s__Thalassobacillus devorans|m__MGYG000001508 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli 1.0 91061|Bacilli 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gapA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1408662 0 0 0 0 1456495 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VVTFLGR MGYG000003645_00336;MGYG000004464_00930;MGYG000001666_01195;MGYG000001780_02982;MGYG000001661_02656;MGYG000002171_02171;MGYG000002905_01300;MGYG000003202_00412;MGYG000000236_02485;MGYG000001378_02334;MGYG000003434_00296;MGYG000000215_01371;MGYG000002033_02334;MGYG000001337_01496;MGYG000002560_03190;MGYG000002455_04306;MGYG000000243_01312;MGYG000001806_01086;MGYG000004823_02033;MGYG000004797_02601;MGYG000004757_00359;MGYG000002478_03183;MGYG000000117_02886;MGYG000000196_00507 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0438@1|root,COG0438@2|Bacteria,4NEWR@976|Bacteroidetes,2FMW0@200643|Bacteroidia,4AKN5@815|Bacteroidaceae 0.5833333333333334 976|Bacteroidetes 1.0 M 0.9583333333333334 Glycosyltransferase, group 1 family protein 0.6666666666666666 gmhA 0.9583333333333334 - 1.0 2.4.1.346 0.9583333333333334 ko:K13668 0.9583333333333334 - 1.0 - 1.0 R11703,R11704 0.9583333333333334 - 1.0 ko00000,ko01000,ko01003 0.9583333333333334 - 1.0 GT4 0.9583333333333334 - 1.0 Glyco_trans_4_4,Glyco_transf_4,Glyco_transf_5,Glycos_transf_1,SIS_2 0.9583333333333334 - 1.0 GT4 1.0 GT4 1.0 GT4 1.0 phosphatidyl-myo-inositol dimannoside synthase. mannosyltransferase. The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs). (1) a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D- myo-inositol] + GDP-alpha-D-mannose = a 2,6-O-bis(alpha-D- mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+). (2) a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl- (1<->6)-D-myo-inositol] + GDP-alpha-D-mannose = 2-O-(alpha-D-mannosyl)-6- O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+). 0.9583333333333334 0.9583333333333334 0.9583333333333334 0.9583333333333334 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642026 0 0 0 0 0 0 0 998123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VVTLGEIMLR MGYG000004748_01870;MGYG000002281_02000;MGYG000001433_00077;MGYG000000013_04444;MGYG000001345_02616;MGYG000000196_03698;MGYG000003351_04347;MGYG000003493_01858;MGYG000002786_00778;MGYG000002291_01855;MGYG000002549_02252;MGYG000000054_04213;MGYG000002478_03488;MGYG000001378_01448;MGYG000004797_00251;MGYG000001806_00682;MGYG000003535_00588 domain d__Bacteria 1.0 COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,2FMMW@200643|Bacteroidia 0.7647058823529411 976|Bacteroidetes 1.0 G 1.0 glucuronate isomerase 0.7647058823529411 uxaC 0.7647058823529411 - 1.0 5.3.1.12 0.7647058823529411 ko:K01812 0.7647058823529411 ko00040,ko01100,map00040,map01100 0.7647058823529411 M00061,M00631 0.7647058823529411 R01482,R01983 0.7647058823529411 RC00376 0.7647058823529411 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 UxaC 0.7647058823529411 - 1.0 - 1.0 - 1.0 - 1.0 glucuronate isomerase. uronic isomerase. Also converts D-galacturonate to D-tagaturonate. D-glucuronate = D-fructuronate. 0.7647058823529411 0.7647058823529411 0.7647058823529411 0.7647058823529411 Pentose and glucuronate interconversions;Metabolic pathways 0.7647058823529411 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 657681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)VYTVTGTWNPDKPR MGYG000000224_01902 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp003545565|m__MGYG000000224 1.0 COG0584@1|root,COG0584@2|Bacteria,4NHVM@976|Bacteroidetes,2FNEP@200643|Bacteroidia,4AP34@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Glycerophosphoryl diester phosphodiesterase family 1.0 glpQ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GDPD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5893141 0 0 0 0 0 0 0 0 0 0 0 3264605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl)WKDVNGDGVIDNYDMVK MGYG000002549_01340;MGYG000000236_04054 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AKMU@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2553555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl_2H(2))ENADIYASLPEGVAR MGYG000000236_04310 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 664223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl_2H(2))IEAGIIHVGDEVEILGLGEDKK MGYG000001789_00154;MGYG000001780_03476;MGYG000002455_03884 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl_2H(2))NMYNGTSGTELMGK MGYG000001346_03050 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 916899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1474523 0 -(Methyl_2H(2))SFATGIAGFSHVVDSLSAIK MGYG000000249_01153;MGYG000000212_03425;MGYG000001338_02009;MGYG000000146_00290;MGYG000000201_01290;MGYG000000142_01268;MGYG000000184_00650;MGYG000000133_01279 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3XZ2A@572511|Blautia 0.75 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 0.75 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 136463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112413 0 5839545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2385888 0 0 0 0 0 0 0 0 0 0 8486436 0 2487768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4831943 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl_2H(2))SGETEDATIADIAVATNSGQIK MGYG000000174_03490;MGYG000000170_00013;MGYG000001780_02258;MGYG000001551_03232;MGYG000001306_00798;MGYG000004823_02623;MGYG000002438_02238;MGYG000002478_00851;MGYG000001461_01176;MGYG000001372_00511;MGYG000000105_02944;MGYG000000781_02456;MGYG000003363_02712;MGYG000003351_05187;MGYG000002033_02968;MGYG000003701_04731;MGYG000002478_03016;MGYG000000243_01149;MGYG000003363_01340;MGYG000000138_00292;MGYG000001787_01497;MGYG000003367_02246;MGYG000000355_00667;MGYG000002438_01170;MGYG000003362_00885;MGYG000002717_02775;MGYG000001346_02829;MGYG000001661_02794;MGYG000003312_00286;MGYG000001552_02061;MGYG000002455_01185;MGYG000002549_00850;MGYG000000196_01187;MGYG000003693_00001;MGYG000002455_05125;MGYG000002540_01420;MGYG000001655_00022;MGYG000000273_02920;MGYG000001364_02911;MGYG000001433_00549;MGYG000000013_00888 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 0.6585365853658537 976|Bacteroidetes 1.0 G 0.975609756097561 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 0.975609756097561 eno 0.975609756097561 - 1.0 4.2.1.11 0.975609756097561 ko:K01689 0.975609756097561 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 0.975609756097561 M00001,M00002,M00003,M00346,M00394 0.975609756097561 R00658 0.975609756097561 RC00349 0.975609756097561 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 0.975609756097561 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 0.975609756097561 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 0.975609756097561 0.975609756097561 0.975609756097561 0.975609756097561 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 0.975609756097561 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl_2H(2))VAGNSAVDFENIDKAPEER MGYG000002234_01026 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus sp900554415|m__MGYG000002234 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,267PG@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 543874 0 -(Methyl_2H(3)13C(1))AIAAQQNTQFQLANMATQVEAAK MGYG000000077_02467;MGYG000000262_02234 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 331962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1305476 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1776800 0 0 0 0 1615341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methyl_2H(3)13C(1))DLIEWVLWNSER MGYG000000243_02761 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1803@1|root,COG1803@2|Bacteria,4NQJ9@976|Bacteroidetes,2FPT5@200643|Bacteroidia,4ANEX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 methylglyoxal synthase 1.0 mgsA 1.0 - 1.0 4.2.3.3 1.0 ko:K01734 1.0 ko00640,ko01120,map00640,map01120 1.0 - 1.0 R01016 1.0 RC00424 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylglyoxal synthase. - Does not act on D-glyceraldehyde 3-phosphate.-!-Formerly EC 4.2.99.11. dihydroxyacetone phosphate = methylglyoxal + phosphate. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16235018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32410441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Methylthio)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2628493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 614736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 852286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 744542 0 0 0 0 0 0 0 0 0 0 0 -(NDA)MLAHLLK MGYG000000038_02185;MGYG000001311_02933;MGYG000003582_01256;MGYG000001558_01857;MGYG000002619_02023;MGYG000003374_01118;MGYG000000771_01164;MGYG000001412_01313;MGYG000000272_02321;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000001763_00396;MGYG000000223_00996;MGYG000001711_02099;MGYG000004732_01055;MGYG000001255_00370;MGYG000001482_02362;MGYG000001496_01122;MGYG000004493_00097;MGYG000000002_02120;MGYG000002194_02222;MGYG000004271_00554;MGYG000002966_00075;MGYG000004317_00142;MGYG000000233_00345;MGYG000001577_01888;MGYG000000174_02692;MGYG000001652_01009;MGYG000000077_00219;MGYG000000127_04855;MGYG000002993_00787;MGYG000002945_00682;MGYG000000229_00395;MGYG000004610_00503;MGYG000002098_00013;MGYG000002212_00259;MGYG000004826_01307;MGYG000001606_02632;MGYG000000213_00374;MGYG000003465_00706;MGYG000001542_01437;MGYG000002517_01026;MGYG000004707_01697;MGYG000000212_01474;MGYG000002126_00535;MGYG000000515_01608;MGYG000001338_02547;MGYG000003074_01265;MGYG000001493_05257;MGYG000004757_01889;MGYG000002141_01131;MGYG000000217_00275;MGYG000001439_00571;MGYG000000280_02459;MGYG000000249_01352;MGYG000003695_01114;MGYG000004691_00618;MGYG000002641_00563;MGYG000000193_03247;MGYG000000140_01181;MGYG000000080_03115;MGYG000002279_00557;MGYG000004799_00704;MGYG000001814_01253;MGYG000003656_01296;MGYG000000242_02076;MGYG000002492_01379;MGYG000000198_04065;MGYG000001334_01647;MGYG000001199_01005;MGYG000001658_00407;MGYG000001688_03910;MGYG000000278_03657;MGYG000001319_00348;MGYG000000495_01130;MGYG000001303_01883;MGYG000000187_02264;MGYG000003504_01686;MGYG000000371_00136;MGYG000004519_00423;MGYG000000097_00328;MGYG000001525_01747;MGYG000000615_00488;MGYG000001423_00991;MGYG000001157_00577;MGYG000000171_00850;MGYG000000195_01135;MGYG000001008_00728;MGYG000000271_03250;MGYG000000562_01218;MGYG000000022_00437;MGYG000000133_02283;MGYG000002298_02410;MGYG000000489_00503;MGYG000004600_00849;MGYG000000399_00360;MGYG000003694_01737;MGYG000001607_01815;MGYG000000230_01325;MGYG000003355_00996;MGYG000000484_01691;MGYG000001710_00672;MGYG000003001_00320;MGYG000000205_02269;MGYG000000145_03615;MGYG000002528_00367;MGYG000004140_01100;MGYG000002188_01071;MGYG000002286_00420;MGYG000000164_00800;MGYG000001748_01525;MGYG000001714_01796;MGYG000002946_02881;MGYG000000150_00838;MGYG000000404_00344;MGYG000004815_01345;MGYG000000141_02825;MGYG000003552_01242;MGYG000003702_00925;MGYG000001781_01334;MGYG000001542_02015;MGYG000002304_00547;MGYG000004740_01468;MGYG000000045_02136;MGYG000000162_00065;MGYG000000089_01653;MGYG000004296_01958;MGYG000002155_00766;MGYG000000179_02084;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000001299_00204;MGYG000000251_00555;MGYG000002992_00164;MGYG000002974_01418;MGYG000002997_01277;MGYG000001237_01808;MGYG000004785_01017;MGYG000002025_02240;MGYG000002963_04095;MGYG000000463_00862;MGYG000001602_01805;MGYG000002052_00078;MGYG000001970_02077;MGYG000004246_01300;MGYG000000153_00303;MGYG000001315_01699;MGYG000001627_00130;MGYG000001469_02299;MGYG000003409_01628;MGYG000003891_00096;MGYG000001310_02090;MGYG000002445_01920;MGYG000000325_00586;MGYG000000909_00644;MGYG000002234_00398;MGYG000003431_01105;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000004809_00788;MGYG000003450_00202;MGYG000003701_01708;MGYG000001954_02254;MGYG000002638_00362;MGYG000000215_01375;MGYG000001065_01088;MGYG000004810_01402;MGYG000000100_02166;MGYG000002131_02428;MGYG000003335_00316;MGYG000000084_01085;MGYG000001300_02008;MGYG000004866_01631;MGYG000003937_01177;MGYG000000252_01324;MGYG000000365_00999;MGYG000000301_01012;MGYG000004722_00591;MGYG000001186_01925;MGYG000004087_02290;MGYG000000312_01508;MGYG000000204_00778;MGYG000003013_01053;MGYG000002857_01020;MGYG000004288_00401;MGYG000000175_00767;MGYG000004714_00143;MGYG000003133_02653;MGYG000000281_02732;MGYG000001619_01736;MGYG000000398_00286;MGYG000001683_01827;MGYG000001421_02311;MGYG000004789_01485;MGYG000003812_01036;MGYG000004735_01946;MGYG000003503_01071;MGYG000004809_00408;MGYG000004593_01977 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.20398009950248755 186801|Clostridia 0.7711442786069652 C 0.5870646766169154 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.47761194029850745 gap 0.9552238805970149 - 0.9154228855721394 1.2.1.12 0.9850746268656716 ko:K00134 0.9850746268656716 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9850746268656716 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9850746268656716 R01061 0.9850746268656716 RC00149 0.9850746268656716 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9850746268656716 - 0.9950248756218906 - 1.0 - 0.9850746268656716 Gp_dh_C,Gp_dh_N 0.9850746268656716 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9850746268656716 0.9850746268656716 0.9850746268656716 0.9850746268656716 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9850746268656716 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347489 0 0 0 0 90633 -(NHS-LC-Biotin)APEKLRIGFTAYKYDDNFIALYR MGYG000002485_00350 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG1879@1|root,COG1879@2|Bacteria,3793S@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(NHS-LC-Biotin)LDGAAQR MGYG000004828_01576;MGYG000002485_02480;MGYG000004893_01506 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 22997 0 0 0 0 0 0 0 179387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163270 0 0 0 6038920 0 6808774 0 5050459 0 0 0 8756444 0 5199827 0 5940872 0 0 0 0 5485988 3437747 5102728 0 4912086 0 6450491 0 0 5736934 5264007 0 0 5307019 4174418 0 3972792 6511879 5174491 112405 0 27252 0 14422 37072 0 0 0 0 43156 0 82895 0 0 0 0 0 0 0 0 34766 0 0 0 112472 0 0 0 24435 0 0 62782 46559 0 73549 0 0 0 0 0 0 0 0 0 0 0 0 25082 0 63483 0 0 0 0 0 0 0 44230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128244 0 34602 0 81287 48706 76486 0 0 0 0 0 43038 0 0 0 0 0 0 62328 109429 39794 0 0 0 31719 0 0 75511 0 0 0 0 0 0 91487 110350 0 -(NIC[AnyN-term](ICPL)LLIGATNIGR MGYG000001300_00291 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 274220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1177803 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463364 0 0 0 0 0 0 0 -(NIC[AnyN-term](ICPL)LVEEATAEHPFQFISGLGTTLER MGYG000000243_00124 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,2FM08@200643|Bacteroidia,4AKD4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 slyD 1.0 - 1.0 5.2.1.8 1.0 ko:K03775 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 FKBP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4527052 0 0 0 0 2968812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3155839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(NP40)EHNLTPILC(Carbamidomethyl)C(Carbamidomethyl)GETLEQR MGYG000002517_01028 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 1029542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1212217 0 0 0 0 0 0 0 0 0 959238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 921889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1840413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2586561 0 0 0 0 0 0 0 0 0 4208327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Phenylisocyanate_2H(5))ADQVDDPELLELVEMEVR MGYG000002994_01317 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Megasphaeraceae|g__Megasphaera|s__Megasphaera sp002319965|m__MGYG000002994 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4H22P@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 10810158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37301044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5148315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Phenylisocyanate_2H(5))ADVIMILINDEK MGYG000000179_02288 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,21XQ9@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 419260 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Phenylisocyanate_2H(5))FMASIEAALEKGDVEAAK MGYG000000029_00498;MGYG000001378_04234;MGYG000002281_03613;MGYG000000196_02323;MGYG000001345_03404;MGYG000000013_01747;MGYG000003312_00912;MGYG000002549_04269;MGYG000000098_00597;MGYG000000054_02343 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449203 0 0 0 0 0 0 0 0 0 0 442462 0 976918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454613 0 0 0 0 0 0 0 0 0 0 490667 0 -(Phenylisocyanate_2H(5))GAGEVVTLDPEESVAYIMGK MGYG000000164_00687 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Phenylisocyanate_2H(5))GKGKGSLEYWVAVVKPGR MGYG000002517_02866 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs 1.0 rplP 1.0 - 1.0 - 1.0 ko:K02878 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 707881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327031 0 0 0 0 0 0 -(Piperidine)AQNNTGFKDHDTGVSPVFAGGVEYAITPEIATR MGYG000003372_01027 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter|s__Citrobacter werkmanii|m__MGYG000003372 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3WWJT@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 M 1.0 OmpA-like transmembrane domain 1.0 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2854652 0 0 0 0 0 2735637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1154874 0 0 0 0 0 1034010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Piperidine)ERTAKEIEIR MGYG000000031_02186;MGYG000000216_01302 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XZ67@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins 1.0 iscS 1.0 - 1.0 2.8.1.7 1.0 ko:K04487 1.0 ko00730,ko01100,ko04122,map00730,map01100,map04122 1.0 - 1.0 R07460,R11528,R11529 1.0 RC01789,RC02313 1.0 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 cysteine desulfurase. cysteine desulfurylase. The sulfur from free L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors.-!-The enzyme is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin).-!-In Azotobacter vinelandii, this sulfur provides the inorganic sulfide required for nitrogenous metallocluster formation. [sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine. 1.0 1.0 1.0 1.0 Thiamine metabolism;Metabolic pathways;Sulfur relay system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Piperidine)LEHTISNLDNISENTSSAESR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 695254 0 0 0 0 0 0 0 0 -(Propionamide)AAAPAPKAAAPA MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1736316 0 0 0 0 0 0 0 0 0 0 0 0 1876093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)AAELVQALK MGYG000000087_01479;MGYG000000198_02625 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,21YF6@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 857005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)AGAVNIVPNSTGAAK MGYG000003409_01628;MGYG000000515_01608;MGYG000002445_01920;MGYG000000325_00586;MGYG000003074_01265;MGYG000001423_00991;MGYG000004735_01946;MGYG000001651_01502;MGYG000000141_02825;MGYG000002025_02240;MGYG000004593_01977;MGYG000001714_01796 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 0.25 186801|Clostridia 0.9166666666666666 G 0.5833333333333334 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 0.9166666666666666 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 197170 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1003447 0 0 0 0 0 0 0 358986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530878 0 0 0 0 0 0 947598 743097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)AGIALTDTFVK MGYG000003589_01892;MGYG000002540_02142;MGYG000001783_01519;MGYG000003457_01802;MGYG000002057_00658;MGYG000004006_01717;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000002944_01470;MGYG000001345_01069;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002006_01638;MGYG000001749_01249;MGYG000002455_02200;MGYG000001356_02656;MGYG000004487_00117;MGYG000001546_00360;MGYG000000086_02423;MGYG000004726_03349;MGYG000004638_00838;MGYG000000377_02142;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000003681_00790;MGYG000000003_00712;MGYG000002933_02039;MGYG000004482_00387;MGYG000000196_00479;MGYG000003693_00860;MGYG000001661_02632;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000002867_00573;MGYG000000053_01377;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.43859649122807015 976|Bacteroidetes 0.6666666666666666 C 0.5614035087719298 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7719298245614035 gap 0.9473684210526315 - 1.0 1.2.1.12 0.9649122807017544 ko:K00134 0.9649122807017544 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9649122807017544 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9649122807017544 R01061 0.9649122807017544 RC00149 0.9649122807017544 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9649122807017544 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 0.9649122807017544 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9649122807017544 0.9649122807017544 0.9649122807017544 0.9649122807017544 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9649122807017544 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3071230 0 0 0 0 2082738 0 0 0 0 0 0 1848836 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2900067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2647601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)AGVPADQVDHVYMGCVIQAGLGQNVAR MGYG000002528_02664;MGYG000000164_00683;MGYG000000501_00162;MGYG000000028_00940;MGYG000000690_01881;MGYG000004359_01902 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.6666666666666666 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1469125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)AIGIPEEELR MGYG000003202_00622 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__UBA3263|s__UBA3263 sp900759865|m__MGYG000003202 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,4AKYT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9827384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)AIGIPEEELRK MGYG000001871_00441 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__|s__|m__MGYG000001871 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,4AKYT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3413234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)AKEKFER MGYG000000042_01421;MGYG000002106_00224;MGYG000001524_01606;MGYG000001630_01142;MGYG000002485_02622;MGYG000004893_01944;MGYG000004893_00932;MGYG000003460_01161;MGYG000003155_00314;MGYG000001925_01419;MGYG000000273_00431;MGYG000001701_00473;MGYG000004763_01689;MGYG000003681_02037;MGYG000001384_04567;MGYG000001464_00103;MGYG000002281_02290;MGYG000003185_01074;MGYG000003992_01709;MGYG000003142_01879;MGYG000002528_01098;MGYG000001313_00097;MGYG000000013_02251;MGYG000003266_00392;MGYG000003583_01411;MGYG000002455_03884;MGYG000000348_00283;MGYG000003628_01000;MGYG000001485_02164;MGYG000000034_01346;MGYG000001141_02439;MGYG000002930_00867;MGYG000003142_01865;MGYG000000196_03974;MGYG000003375_00698;MGYG000004573_00004;MGYG000001661_02666;MGYG000003851_00676;MGYG000002762_01733;MGYG000000121_02189;MGYG000001789_00154;MGYG000001567_01738;MGYG000000182_00585;MGYG000000054_03933;MGYG000000236_01807;MGYG000000098_02017;MGYG000002291_02272;MGYG000003185_01053;MGYG000002556_01332;MGYG000000036_01380;MGYG000000445_01370;MGYG000001346_01533;MGYG000000243_01988;MGYG000001780_03476;MGYG000002540_03367;MGYG000001646_01118;MGYG000003073_01160;MGYG000003514_00785;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.23728813559322035 976|Bacteroidetes 0.4915254237288136 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9830508474576272 tuf 1.0 - 0.847457627118644 - 1.0 ko:K02358 0.9830508474576272 - 0.9830508474576272 - 0.9830508474576272 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9830508474576272 - 0.9830508474576272 - 1.0 - 0.9491525423728814 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9830508474576272 none 1.0 0 0 1240537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133338 1279505 0 0 0 0 642122 0 0 136093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365959 117514 0 0 0 0 79448 0 0 430732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247889 271666 0 0 0 0 277753 0 0 292060 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216293 156941 0 0 0 0 266723 0 0 58577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320510 0 0 0 0 0 364122 -(Propionamide)ALAQVEK MGYG000003683_00219 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CYYY@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 L 1.0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage 1.0 recA 1.0 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 1.0 - 1.0 ko:K03553 1.0 ko03440,map03440 1.0 M00729 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03400 1.0 - 1.0 - 1.0 - 1.0 ABC2_membrane,Intein_splicing,LAGLIDADG_2,LAGLIDADG_3,Rad51,RecA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Homologous recombination 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1988227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)ALEAGVNQLADTVR MGYG000000080_01156;MGYG000000077_00451;MGYG000003486_00745;MGYG000001607_00737;MGYG000001619_01799;MGYG000000146_01484;MGYG000004317_02207;MGYG000002528_02459;MGYG000001714_01961;MGYG000003239_01867;MGYG000000179_05119;MGYG000001683_01057;MGYG000002445_00865;MGYG000000217_01904;MGYG000001531_01706;MGYG000000242_00061;MGYG000001065_00812;MGYG000004087_02347;MGYG000003828_02241;MGYG000000262_01443;MGYG000002279_00394;MGYG000000909_02638;MGYG000001707_02383 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2681F@186813|unclassified Clostridiales 0.30434782608695654 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)ALLHVAK MGYG000002494_03016 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,3XM8F@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes 1.0 lpdA 1.0 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0019438,GO:0019464,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045250,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0065007,GO:0065008,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.0 1.8.1.4 1.0 ko:K00382 1.0 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00036,M00307,M00532 1.0 R00209,R01221,R01698,R03815,R07618,R08549 1.0 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 1.0 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_1869,iEcolC_1368.EcolC_3543,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385 1.0 Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim 1.0 - 1.0 - 1.0 - 1.0 - 1.0 dihydrolipoyl dehydrogenase. L-protein. A component of the multienzyme 2-oxo-acid dehydrogenase complexes.-!-In the pyruvate dehydrogenase complex, it binds to the core of EC 2.3.1.12 and catalyzes oxidation of its dihydrolipoyl groups.-!-It plays a similar role in the oxoglutarate and 3-methyl-2- oxobutanoate dehydrogenase complexes.-!-Another substrate is the dihydrolipoyl group in the H-protein of the glycine-cleavage system, in which it acts, together with EC 1.4.4.2 and EC 2.1.2.10 to break down glycine.-!-It can also use free dihydrolipoate, dihydrolipoamide or dihydrolipoyllysine as substrate.-!-Was first shown to catalyze the oxidation of NADH by methylene blue; this activity was called diaphorase.-!-The glycine cleavage system is composed of four components that only loosely associate: the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H protein.-!-Formerly EC 1.6.4.3. N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = H(+) + N(6)-[(R)- lipoyl]-L-lysyl-[protein] + NADH. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 941562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)ALSATDGDMDKAVEFLR MGYG000000205_00610;MGYG000000255_00470 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,21ZJJ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)ATDGILAR MGYG000004797_01549 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,2FNCA@200643|Bacteroidia,4AM99@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG0427 Acetyl-CoA hydrolase 1.0 scpC 1.0 - 1.0 2.8.3.18,3.1.2.1 1.0 ko:K01067,ko:K18118 1.0 ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011 1.0 R00227,R10343 1.0 RC00004,RC00012,RC00014 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinyl-CoA:acetate CoA-transferase. | acetyl-CoA hydrolase. SCACT. | acetyl-CoA deacylase. In some bacteria the enzyme catalyzes the conversion of acetate to acetyl-CoA as part of a modified tricarboxylic acid (TCA) cycle.-!-In other organisms it converts acetyl-CoA to acetate during fermentation.-!-In some organisms the enzyme also catalyzes the activity of EC 2.8.3.27. acetate + succinyl-CoA = acetyl-CoA + succinate. | acetyl-CoA + H2O = acetate + CoA + H(+). 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 440579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 852667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2087756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2903803 0 0 0 0 0 0 -(Propionamide)AVDDKVLAALAK MGYG000001315_01172 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 2.2.1.2,5.3.1.9 1.0 ko:K01810,ko:K13810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00004,M00007,M00114 1.0 R01827,R02739,R02740,R03321 1.0 RC00376,RC00439,RC00563,RC00604 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. | glucose-6-phosphate isomerase. glycerone transferase. | phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)AYVDAK MGYG000002478_03973 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,2FNN5@200643|Bacteroidia,4AP04@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG0058 Glucan phosphorylase 1.0 glgP 1.0 - 1.0 2.4.1.1,2.4.1.11,2.4.1.8 1.0 ko:K00688,ko:K00691,ko:K16153 1.0 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 1.0 - 1.0 R00292,R01555,R02111 1.0 RC00005,RC00049 1.0 ko00000,ko00001,ko01000,ko01003 1.0 - 1.0 GH65,GT3,GT35 1.0 - 1.0 DUF3417,Glycogen_syn,Phosphorylase 1.0 2.4.1.1 1.0 GT35 1.0 GT35 1.0 GT35 1.0 glycogen phosphorylase. | glycogen(starch) synthase. | maltose phosphorylase. polyphosphorylase. | UDP-glucose--glycogen glucosyltransferase. This entry covers several enzymes from different sources that act in vivo on different forms of (1->4)-alpha-D-glucans.-!-Some of these enzymes catalyze the first step in the degradation of large branched glycan polymers - the phosphorolytic cleavage of alpha-1,4-glucosidic bonds from the non-reducing ends of linear poly(1->4)-alpha-D-glucosyl chains within the polymers.-!-The enzyme stops when it reaches the fourth residue away from an alpha-1,6 branching point, leaving a highly branched core known as a limit dextrin.-!-The description (accepted name) of the enzyme should be modified for each specific instance by substituting 'glycogen' with the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, etc. | The description (official name) varies according to the source of the enzyme and the nature of its synthetic product.-!-Glycogen synthase from animal tissues is a complex of a catalytic subunit and the protein glycogenin.-!-The enzyme requires glucosylated glycogenin as a primer; this is the reaction product of EC 2.4.1.186.-!-A similar enzyme utilizes ADP-glucose (cf. EC 2.4.1.21). [(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. | [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D- glucosyl](n+1) + H(+) + UDP. | D-maltose + phosphate = beta-D-glucose 1-phosphate + D-glucose. 1.0 1.0 1.0 1.0 Necroptosis;Biofilm formation - Escherichia coli;Metabolic pathways;Starch and sucrose metabolism;Insulin resistance;Glucagon signaling pathway;Biosynthesis of secondary metabolites;Insulin signaling pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3488127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)CDAFNAAHPNWDLTFK MGYG000001319_02248 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia,4BYAS@830|Butyrivibrio 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9707100 0 0 0 0 12124811 0 0 0 0 13445799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)DAEALKK MGYG000001619_00896 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA9502|s__UBA9502 sp900540335|m__MGYG000001619 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1453562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)DAVLTAK MGYG000003693_01161 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG1546@1|root,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,2FMFI@200643|Bacteroidia,4APD5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Belongs to the CinA family 1.0 cinA 1.0 - 1.0 3.5.1.42 1.0 ko:K03742,ko:K03743 1.0 ko00760,map00760 1.0 - 1.0 R02322 1.0 RC00100 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CinA,MoCF_biosynth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 nicotinamide-nucleotide amidase. - Also acts more slowly on beta-nicotinamide D-ribonucleoside. beta-nicotinamide D-ribonucleotide + H2O = NH4(+) + nicotinate beta-D- ribonucleotide. 1.0 1.0 1.0 1.0 Nicotinate and nicotinamide metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20501219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)DELGVKGAFTSAGMDGSSDWR MGYG000000201_01623 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066145|m__MGYG000000201 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3XZHY@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 GH49 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2357966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)DGAFKDEIVPVVIKGK MGYG000002274_00043;MGYG000001300_00296;MGYG000003937_01092;MGYG000002619_02240 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)DGEMEYGVGIHGEPGIQR MGYG000000050_00164 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066505|m__MGYG000000050 1.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,36E0T@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Dihydroxyacetone kinase DhaK, subunit 1.0 dhaK 1.0 - 1.0 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 1.0 ko:K00863,ko:K05878 1.0 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 1.0 M00344 1.0 R01011,R01012,R01059 1.0 RC00002,RC00015,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak1,Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. | triokinase. | glycerone kinase. | FAD-AMP lyase (cyclizing). triose kinase. | dihydroxyacetone kinase. | FMN cyclase. While FAD was the best substrate tested the enzyme also splits ribonucleoside diphosphate-X compounds in which X is an acyclic or cyclic monosaccharide or derivative bearing an X-OH group that is able to attack internally the proximal phosphorus with the geometry necessary to form a P=X product; either a five-atom monocyclic phosphodiester or a cis-bicyclic phosphodiester-pyranose fusion.-!-The reaction is strongly inhibited by ADP or ATP but is unaffected by the presence of the product, cFMN. dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. | ATP + D-glyceraldehyde = ADP + D-glyceraldehyde 3-phosphate + H(+). | ATP + dihydroxyacetone = ADP + dihydroxyacetone phosphate + H(+). | FAD = AMP + H(+) + riboflavin cyclic-4',5'-phosphate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RIG-I-like receptor signaling pathway;Glycerolipid metabolism;Metabolic pathways;Fructose and mannose metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9828999 0 0 4586331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6626574 0 9065325 0 0 0 0 0 0 0 0 12879149 0 0 0 0 7305238 -(Propionamide)DIGLTDADLAGQYQYTK MGYG000000022_00102 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1119888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)DSGCNVIIGLYEGSK MGYG000001315_02512;MGYG000004740_00571;MGYG000002492_01825;MGYG000002670_02165 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,25VBQ@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 H 0.75 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 0.75 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1565089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1617591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)EALHILK MGYG000002171_00028;MGYG000000243_00429 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0156@1|root,COG0156@2|Bacteria,4NJ3B@976|Bacteroidetes,2G2VS@200643|Bacteroidia,4AW5T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.3.1.47 1.0 ko:K00652 1.0 ko00780,ko01100,map00780,map01100 1.0 M00123,M00573,M00577 1.0 R03210,R10124 1.0 RC00004,RC00039,RC02725 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 AMP-binding,AMP-binding_C,Aminotran_1_2,PP-binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 8-amino-7-oxononanoate synthase. AONS. The enzyme catalyzes the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis.-!-Pimeloyl-CoA can be used with lower efficiency. 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]. 1.0 1.0 1.0 1.0 Biotin metabolism;Metabolic pathways 1.0 none 1.0 618439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 817154 0 0 0 0 0 0 0 0 0 0 708267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 839412 0 0 0 0 0 0 0 0 0 0 1126607 0 6191722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7424762 0 0 0 0 0 0 0 0 0 0 9259566 0 3702087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2189435 0 0 0 0 0 0 0 0 0 0 3009733 0 -(Propionamide)EGINEAMK MGYG000001683_01827 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Frisingicoccus|s__|m__MGYG000001683 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1833902 0 0 0 0 0 0 -(Propionamide)ELFNLR MGYG000000087_00997;MGYG000002040_00978;MGYG000004714_00674;MGYG000001365_00966;MGYG000003921_00351;MGYG000003166_00767;MGYG000002965_00666;MGYG000001748_00602;MGYG000000249_01543;MGYG000003899_00622;MGYG000004271_00024;MGYG000001636_00354;MGYG000000177_02168;MGYG000000133_00053;MGYG000001602_00388;MGYG000002393_00687;MGYG000002279_01064;MGYG000000184_01180;MGYG000000136_02070;MGYG000000251_01823;MGYG000001488_02376;MGYG000002272_00459;MGYG000004681_00019;MGYG000002945_02576;MGYG000004285_00578;MGYG000001607_01093;MGYG000001642_00142;MGYG000004733_00976;MGYG000001423_01146;MGYG000002619_02378;MGYG000004158_01539;MGYG000002670_00394;MGYG000003693_01253;MGYG000004769_00447;MGYG000000204_02168;MGYG000000159_01019;MGYG000002395_00358;MGYG000000195_02125;MGYG000000515_01667;MGYG000002517_02865;MGYG000002304_02163;MGYG000002557_00162;MGYG000000301_00168;MGYG000002978_01111;MGYG000001300_02207;MGYG000000193_02104;MGYG000002791_01000;MGYG000001652_00830;MGYG000000217_01262;MGYG000001292_02354;MGYG000000268_01519;MGYG000002202_01351;MGYG000002528_01847;MGYG000002074_00244;MGYG000004630_00943;MGYG000002772_00329;MGYG000001338_02799;MGYG000000233_02351;MGYG000003486_01262;MGYG000001567_01817;MGYG000000198_04895;MGYG000002445_01504;MGYG000000802_00715;MGYG000000255_01832;MGYG000004783_00291;MGYG000000039_01693;MGYG000001315_01344;MGYG000000194_02274;MGYG000000092_00988;MGYG000000140_01891;MGYG000002274_00837;MGYG000000325_01670;MGYG000003683_01130;MGYG000004894_01025;MGYG000000200_01105;MGYG000000911_00432;MGYG000000262_00154;MGYG000003459_00664;MGYG000004894_00604;MGYG000000693_00199;MGYG000000028_01614;MGYG000002968_01155;MGYG000002963_00446;MGYG000003422_00858;MGYG000000022_02032;MGYG000002702_01359;MGYG000003425_03563;MGYG000000420_00594;MGYG000004851_00265;MGYG000000258_00289;MGYG000002065_01091;MGYG000000562_01922;MGYG000002919_00423;MGYG000003937_00259;MGYG000000756_00960;MGYG000003074_00527;MGYG000002756_00361;MGYG000000084_01010;MGYG000000036_00617;MGYG000000281_01467;MGYG000000392_01453;MGYG000002998_00178;MGYG000000038_01584;MGYG000000312_01456;MGYG000000243_00039;MGYG000000271_01069;MGYG000002560_02573;MGYG000004140_01823;MGYG000002966_02567;MGYG000001707_02038;MGYG000004039_00542;MGYG000001627_01320;MGYG000000119_00093;MGYG000004558_00368;MGYG000003266_00868;MGYG000000080_02263;MGYG000003465_00835;MGYG000003922_01732;MGYG000000213_00206;MGYG000001439_02151;MGYG000000489_01450;MGYG000002545_01132;MGYG000000484_00183;MGYG000002459_00387;MGYG000002469_01761;MGYG000001645_00448;MGYG000004869_03328;MGYG000000245_02646;MGYG000000989_00148;MGYG000001814_02459;MGYG000003147_00988;MGYG000002641_00980;MGYG000004718_00070;MGYG000002651_00740;MGYG000003452_00880;MGYG000000417_00386;MGYG000004681_01725;MGYG000000206_01042;MGYG000001496_03128;MGYG000002492_00383;MGYG000004716_01214;MGYG000000002_00874;MGYG000001543_00409;MGYG000001374_01188;MGYG000000179_04592;MGYG000004642_00859;MGYG000001255_02125;MGYG000004762_01326 domain d__Bacteria 1.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae 0.20270270270270271 186801|Clostridia 0.7702702702702703 J 0.9594594594594594 Belongs to the universal ribosomal protein uL29 family 0.8108108108108109 rpmC 0.9391891891891891 - 0.918918918918919 - 0.9662162162162162 ko:K02904 0.9391891891891891 ko03010,map03010 0.9594594594594594 M00178,M00179 0.9391891891891891 - 0.972972972972973 - 0.972972972972973 br01610,ko00000,ko00001,ko00002,ko03011 0.9594594594594594 - 1.0 - 0.9797297297297297 - 1.0 Ribosomal_L29 0.918918918918919 - 0.9864864864864865 - 0.9797297297297297 - 0.9797297297297297 - 0.9797297297297297 - - - - 0.9662162162162162 0.9662162162162162 0.9662162162162162 0.9662162162162162 Ribosome 0.9594594594594594 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775214 0 0 0 0 0 0 -(Propionamide)EQNAAAADPNWK MGYG000000074_02571 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG4772@1|root,COG4772@2|Bacteria,4NEJW@976|Bacteroidetes,2G3F5@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1861050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)ESVNVPAGK MGYG000000099_01985 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0860@1|root,COG0860@2|Bacteria,1UMXD@1239|Firmicutes,25GRN@186801|Clostridia,26CS5@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 M 1.0 S-layer homology domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5330795 0 0 0 0 0 0 1578702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1790407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)FCLDDNDANTPR MGYG000000074_00675 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1409@1|root,COG1409@2|Bacteria,4PNR4@976|Bacteroidetes,2FZJW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Putative binding domain, N-terminal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BACON 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5584054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5170962 0 0 0 0 0 0 -(Propionamide)FEPDTIIALGGGSAMDAGK MGYG000001310_00117 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)FVTPVGPYFK MGYG000000196_04103;MGYG000001345_01382;MGYG000000243_02172;MGYG000002478_00294 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,2FMPE@200643|Bacteroidia,4AMTS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase 1.0 ilvE 1.0 - 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways;Cysteine and methionine metabolism;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GDDPNTAWEK MGYG000000271_00306;MGYG000002025_00961;MGYG000002989_01139;MGYG000000142_02730;MGYG000004733_02765;MGYG000000909_01068;MGYG000000133_00505;MGYG000000216_01908;MGYG000001338_01295;MGYG000001619_00079;MGYG000004740_00559;MGYG000002517_01687;MGYG000000262_01833;MGYG000000301_00648;MGYG000000198_05682 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,25V1D@186806|Eubacteriaceae 0.9333333333333333 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.9333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1087589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GDKIVQM(Oxidation)NYDAIDAGAK MGYG000001315_01946;MGYG000001496_03305 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,27VFG@189330|Dorea 0.5 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1048292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GDKIVQMNYDAIDAGAK MGYG000001315_01946;MGYG000001496_03305 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,27VFG@189330|Dorea 0.5 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6097800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GFDGDNTPIIR MGYG000000446_00437 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__RF39|f__UBA660|g__UMGS1045|s__UMGS1045 sp900547995|m__MGYG000000446 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,3VNVP@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1158458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GFYPDGK MGYG000000217_02614;MGYG000000018_02138 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14069695 0 0 0 0 16905229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 804867 0 0 0 0 604698 0 0 0 0 643884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 510162 0 0 0 0 481748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 600625 0 0 0 0 279299 0 0 0 0 306890 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GGAEFMDYSMIDKAPEER MGYG000001365_00649;MGYG000003868_01133;MGYG000003868_01166;MGYG000004769_00412;MGYG000002659_00459;MGYG000004769_00437 family d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4H22P@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GHYAVPAANIVNLENIK MGYG000002528_01589 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0191@1|root,COG0191@2|Bacteria,1TRQY@1239|Firmicutes,24DXB@186801|Clostridia,36VQR@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Fructose-bisphosphate aldolase class-II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 115250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185139 0 0 0 0 0 0 0 489240 429911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10638822 0 0 0 0 227540 0 0 886995 375431 0 0 0 0 586031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742028 340586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 118107 0 0 0 0 0 0 853190 0 0 840140 536285 0 0 0 0 0 0 0 0 0 0 218268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GIPIIADGGIK MGYG000001338_00214;MGYG000004785_01919 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GLNVADVPR MGYG000001496_01244 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Extibacter|s__Extibacter sp001185345|m__MGYG000001496 1.0 COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,24BF2@186801|Clostridia,2209B@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Peptidase family M20/M25/M40 1.0 amaB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GLSKEELASGDYSK MGYG000003351_05248 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900765785|m__MGYG000003351 1.0 COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,2FNWR@200643|Bacteroidia,4ANEE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 COG COG1082 Sugar phosphate isomerases epimerases 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1074775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GQYIKSATLTSTMGPGVK MGYG000002670_00356 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp900546625|m__MGYG000002670 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GTSAPEFTLVK MGYG000002478_04382 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG2077@1|root,COG2077@2|Bacteria,4NNGR@976|Bacteroidetes,2FSI3@200643|Bacteroidia,4AMD1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides 1.0 tpx 1.0 - 1.0 1.11.1.15 1.0 ko:K11065 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Redoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 and 1.11.1.29. - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4254092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GTTAESLAGLR MGYG000002528_02664 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12267377 0 0 0 3529805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7520176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9643749 3791346 0 0 1905166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3623681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4646338 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)GVDKNEIKR MGYG000000196_03974;MGYG000000236_01807;MGYG000004763_01689;MGYG000000013_02251;MGYG000002281_02290 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1371303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)IAAFQNTQFELAEMK MGYG000000195_01571 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_E|m__MGYG000000195 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WI1F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 634169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1461983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)IGGGMGC(Carbamidomethyl)STIVERD MGYG000000262_02231;MGYG000000077_02464;MGYG000002517_00540 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 0.6666666666666666 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2205336 0 4289485 0 0 1976983 0 0 2335792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3282563 3141873 0 0 0 0 0 0 1797934 0 0 3965450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)IGSIAQMATMR MGYG000003701_02275 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides sp003480915|m__MGYG000003701 1.0 COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,2FMB3@200643|Bacteroidia,22WM9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Myo-inositol-1-phosphate synthase 1.0 ino1 1.0 - 1.0 5.5.1.4 1.0 ko:K01858 1.0 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 1.0 - 1.0 R07324 1.0 RC01804 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Inos-1-P_synth,NAD_binding_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 inositol-3-phosphate synthase. myo-inositol-1-phosphate synthase. The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the -CHO at C-1; finally, the enzyme-bound NADH reconverts C-5 into the -CHOH- form. D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Inositol phosphate metabolism;Streptomycin biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 526411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1580154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)IGVLAAYYTDGTTITK MGYG000000003_01533 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 2DX4F@1|root,343BI@2|Bacteria,4P5MZ@976|Bacteroidetes,2FVJX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 1428652 0 0 1365363 0 0 0 0 0 1333680 0 0 0 0 0 1973648 0 0 0 0 0 0 0 0 1312218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 619053 0 0 741147 0 0 0 0 0 631012 0 0 0 0 0 697001 0 0 0 0 0 0 0 0 905461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)IMNPDDKAGLEAALR MGYG000001637_02230;MGYG000004740_00274;MGYG000000087_01268;MGYG000001367_03001;MGYG000002067_00419;MGYG000001615_04300;MGYG000000164_00687;MGYG000003074_00586;MGYG000002141_01824;MGYG000000255_01557;MGYG000001315_01867;MGYG000000489_01026;MGYG000001617_02046;MGYG000000018_00072;MGYG000000077_02468;MGYG000002278_01894;MGYG000004719_02002;MGYG000004055_00051;MGYG000000997_00555;MGYG000000127_04021;MGYG000001777_01059;MGYG000000312_02426;MGYG000001809_02343;MGYG000002445_02276;MGYG000002945_00738;MGYG000003801_01544;MGYG000002528_02668;MGYG000003702_03102;MGYG000001749_01451;MGYG000004359_01906;MGYG000000028_00944;MGYG000000271_02101;MGYG000000404_01798;MGYG000000398_00614;MGYG000002492_00660;MGYG000000154_01281;MGYG000002517_00543;MGYG000004762_01002;MGYG000000262_02235;MGYG000003381_01959;MGYG000003486_02521;MGYG000001319_02234 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.4523809523809524 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.4523809523809524 etfB 1.0 - 0.9047619047619048 - 0.8333333333333334 ko:K03521 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.8333333333333334 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1417897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)IPHVEIVR MGYG000000668_02273 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Anaerovoracaceae|g__CAG-238|s__CAG-238 sp900551415|m__MGYG000000668 1.0 COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,25UUF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 E 1.0 Lysine-2,3-aminomutase 1.0 kamA 1.0 - 1.0 5.4.3.2 1.0 ko:K01843 1.0 ko00310,map00310 1.0 - 1.0 R00461 1.0 RC00303 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,LAM_C,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine 2,3-aminomutase. - This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-It contains pyridoxal phosphate and a [4Fe-4S] cluster and binds an exchangeable S-adenosyl-L-methionine molecule.-!-Activity in vitro requires a strong reductant such as dithionite and strictly anaerobic conditions.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of S-adenosyl-L-methionine, mediated by the iron- sulfur cluster.-!-S-adenosyl-L-methionine is regenerated at the end of the reaction. L-lysine = (3S)-3,6-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1230475 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)ISEEIGKTPVQVEEAAGFVVNR MGYG000004604_00971;MGYG000000233_02444;MGYG000000164_00685;MGYG000000255_01554;MGYG000002945_00736;MGYG000000087_01270 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,27IK9@186928|unclassified Lachnospiraceae 0.6666666666666666 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 0.6666666666666666 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 3851068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3336254 0 0 0 0 0 0 3335122 5519113 1983954 0 0 0 0 2065659 330979 1148166 0 0 0 675983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459245 0 977971 0 0 0 0 0 0 1367651 391540 560358 0 296039 0 0 0 910554 788028 424304 0 0 0 0 1011924 0 0 0 0 0 0 0 0 0 0 0 940080 0 0 0 0 0 929256 0 0 0 0 0 0 0 0 1653015 0 0 616808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)IVDAIPYVESER MGYG000004667_05620 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium|s__Clostridium beijerinckii|m__MGYG000004667 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36EFE@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7959231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)LATGEKLGAFALTEPGAGTDAQGAQTK MGYG000000271_02102;MGYG000002517_00542;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 839129 0 0 0 0 0 1431895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)LIIADLNR MGYG000000312_01941 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eisenbergiella|s__Eisenbergiella sp900539715|m__MGYG000000312 1.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,27IZN@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 - 1.0 - 1.0 ko:K03695,ko:K03696 1.0 ko01100,ko04213,map01100,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N,UVR 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways;Longevity regulating pathway - multiple species 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)LPKTGVVAK MGYG000000217_02552 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Acetatifactor|s__Acetatifactor sp900066565|m__MGYG000000217 1.0 COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,36E1P@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 glutamate synthase (NADPH), homotetrameric 1.0 gltA 1.0 - 1.0 1.17.1.9,1.4.1.13,1.4.1.14 1.0 ko:K00123,ko:K00266 1.0 ko00250,ko00630,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00250,map00630,map00680,map00910,map01100,map01110,map01120,map01130,map01200,map01230 1.0 - 1.0 R00093,R00114,R00248,R00519 1.0 RC00006,RC00010,RC02796,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fer2_4,Fer4,Fer4_20,Molybdop_Fe4S4,Molybdopterin,NAD_binding_1,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate dehydrogenase. | glutamate synthase (NADPH). | glutamate synthase (NADH). NAD(+)-formate dehydrogenase. | NADPH-glutamate synthase. | NADH-glutamate synthase. The enzyme from most aerobic organisms is devoid of redox-active centers but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centers, flavin and a molybdenum center.-!-Together with EC 1.12.1.2, forms a system previously known as formate hydrogenlyase.-!-Formerly EC 1.2.1.2. | The reaction takes place in the opposite direction.-!-The protein is composed of two subunits, alpha and beta.-!-The alpha subunit is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.4).-!-The beta subunit transfers electrons from the cosubstrate.-!-The NH3 is channeled through a 31 A channel in the active protein.-!-In the absence of the beta subunit, coupling between the two domains of the alpha subunit is compromised and some ammonium can be produced.-!-In the intact alphabeta complex, ammonia production only takes place as part of the overall reaction.-!-Formerly EC 2.6.1.53. | A flavoprotein (FMN).-!-The reaction takes place in the direction of L-glutamate production.-!-The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2). formate + NAD(+) = CO2 + NADH. | 2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH. | 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Nitrogen metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1442493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)LPLALK MGYG000000127_00702;MGYG000000133_00543;MGYG000000301_01106 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 E 0.6666666666666666 Psort location CytoplasmicMembrane, score 10.00 0.6666666666666666 agcS 0.6666666666666666 - 1.0 - 0.6666666666666666 ko:K03310 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 ko00000 0.6666666666666666 2.A.25 0.6666666666666666 - 1.0 - 1.0 Na_Ala_symp 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1084924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)LQNDFTGVLTGK MGYG000003455_00764 genome d__Archaea|p__Thermoplasmatota|c__Thermoplasmata|o__Methanomassiliicoccales|f__Methanomethylophilaceae|g__UBA71|s__UBA71 sp900767505|m__MGYG000003455 1.0 COG0334@1|root,arCOG01352@2157|Archaea,2XU0F@28890|Euryarchaeota,3F2GY@33867|unclassified Euryarchaeota 1.0 28890|Euryarchaeota 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 1.4.1.2,1.4.1.3,1.4.1.4 1.0 ko:K00260,ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase. | glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). | (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Taurine and hypotaurine metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)LSTTITGLEMFR MGYG000003166_01350;MGYG000000022_02283;MGYG000002224_01123;MGYG000002040_01212;MGYG000002272_01482 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 552144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394356 0 0 0 0 266690 0 0 172748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)LYEALEGC(Carbamidomethyl)PVTIR MGYG000000417_00539;MGYG000000153_02081;MGYG000000280_02154;MGYG000004810_00381;MGYG000000154_00436;MGYG000002670_01671;MGYG000004517_00262;MGYG000003307_01519;MGYG000000392_01615;MGYG000001756_01779;MGYG000000404_01435;MGYG000002492_01692;MGYG000001652_01307;MGYG000002517_01243;MGYG000000489_00801;MGYG000001637_01169;MGYG000003694_01656;MGYG000003422_01232 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 0.5 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8333333333333334 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1036002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)MAQLALGMVETR MGYG000000268_01898 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Schaedlerella|s__Schaedlerella sp900066545|m__MGYG000000268 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1319156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)MVVQHNLTAM(Oxidation)NANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 903892 1203227 0 2847612 0 656978 2515732 0 746584 0 0 2120241 0 0 0 0 0 0 0 0 0 665848 0 1730909 0 0 2030679 0 0 912978 0 0 0 0 0 887586 879951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032376 655484 0 1569731 0 657194 267204 0 785072 0 0 856521 0 0 0 0 0 0 0 0 0 104490 0 402527 0 558656 275150 0 0 984576 0 0 0 0 0 680520 999507 0 -(Propionamide)NGAILITTK MGYG000000196_00769 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4AWE8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2464228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)NIPGVK MGYG000000080_02256;MGYG000001781_02370;MGYG000000036_00624;MGYG000000045_02210;MGYG000004158_01532;MGYG000000255_02599;MGYG000002857_00040;MGYG000004727_00006;MGYG000003937_00266;MGYG000001319_01323;MGYG000002777_00388;MGYG000003453_00779 domain d__Bacteria 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,36DFP@31979|Clostridiaceae 0.3333333333333333 186801|Clostridia 0.75 J 0.9166666666666666 Forms part of the polypeptide exit tunnel 0.9166666666666666 rplD 0.9166666666666666 - 0.9166666666666666 - 0.9166666666666666 ko:K02926 0.8333333333333334 ko03010,map03010 0.9166666666666666 M00178 0.9166666666666666 - 0.9166666666666666 - 0.9166666666666666 br01610,ko00000,ko00001,ko00002,ko03011 0.9166666666666666 - 1.0 - 1.0 - 1.0 Ribosomal_L4 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9166666666666666 0.9166666666666666 0.9166666666666666 0.9166666666666666 Ribosome 0.9166666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7954091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)NLDNISENTSSAESR MGYG000003694_00680;MGYG000001186_01647;MGYG000002517_00135;MGYG000003694_02093 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14516171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)NMFALLGK MGYG000002040_00814;MGYG000003291_01409;MGYG000001300_02540;MGYG000003899_00328 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WHJX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742072 0 484639 0 0 0 0 0 0 0 0 530353 0 0 0 0 59620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 69530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)NPEVQFC(Carbamidomethyl)HSTGTR MGYG000002794_01702 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp003487665|m__MGYG000002794 1.0 COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia,2N8Z1@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate-binding protein PnrA-like 1.0 - 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3648888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)QIEETTSDFDREK MGYG000000919_03652;MGYG000000202_00541;MGYG000002992_01078;MGYG000000038_02089;MGYG000003486_00745;MGYG000001607_00737;MGYG000001496_00484;MGYG000000278_02028;MGYG000000179_05119;MGYG000001615_01161;MGYG000000198_00464;MGYG000002445_00865;MGYG000000217_01904;MGYG000003783_01372;MGYG000001367_02937;MGYG000001688_01574;MGYG000001617_04641;MGYG000004087_02347;MGYG000000262_01443;MGYG000001193_01063;MGYG000002247_01828;MGYG000002279_00394 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,21YIV@1506553|Lachnoclostridium 0.4090909090909091 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.9545454545454546 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1495015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)QLEEAGAEVELK MGYG000000053_00901;MGYG000000044_01728;MGYG000000183_03084;MGYG000003202_00136;MGYG000004468_00169;MGYG000001562_01082;MGYG000002082_01855;MGYG000003701_03116;MGYG000003279_00958;MGYG000000825_01460;MGYG000004006_00426;MGYG000003282_01991;MGYG000004830_01657;MGYG000001546_01548;MGYG000004469_00969;MGYG000002867_00700;MGYG000001655_02927;MGYG000001608_02199;MGYG000002007_00362;MGYG000001489_05034;MGYG000000003_02516;MGYG000000138_00672;MGYG000002438_02328;MGYG000000117_01470;MGYG000002033_01014;MGYG000004573_00011;MGYG000003172_00544;MGYG000002203_00881;MGYG000000254_02576;MGYG000000074_01766;MGYG000000144_02611;MGYG000003498_00517;MGYG000004711_00303;MGYG000000222_01120;MGYG000001552_00977;MGYG000004658_01198;MGYG000002556_01325 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 0.43243243243243246 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 0.972972972972973 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1102722 0 1071526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)QYAVVLAVAK MGYG000000200_01752 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp003471165|m__MGYG000000200 1.0 COG3209@1|root,COG3209@2|Bacteria,1TRJ1@1239|Firmicutes,24AU6@186801|Clostridia,3WHF3@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 M 1.0 COG3209 Rhs family protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Big_2,Flg_new,Fn3_assoc,LRR_5,Lipase_3,N_methyl,Peptidase_M15_4,Transglut_core 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3692564 0 0 0 0 3156864 0 0 0 0 2749352 0 0 0 5326412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1332889 0 0 0 0 0 0 0 0 0 1679658 0 0 0 5693129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2680250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428964 0 0 0 0 481445 0 0 0 1173532 0 0 0 0 0 0 -(Propionamide)RPEPYKGK MGYG000004558_00361;MGYG000002534_00407;MGYG000002494_02454;MGYG000000154_01823;MGYG000002148_03762;MGYG000000198_04902;MGYG000002445_01497;MGYG000000142_02052;MGYG000000136_02063;MGYG000000181_01077;MGYG000000205_02189;MGYG000002517_02858;MGYG000000280_01282;MGYG000000118_00219;MGYG000000235_04525;MGYG000000515_01674;MGYG000002835_00991;MGYG000000200_01098;MGYG000000249_01536;MGYG000004271_00031;MGYG000004740_00882;MGYG000001714_01313;MGYG000002141_01709;MGYG000000164_02749;MGYG000004869_03335;MGYG000000212_03062;MGYG000001617_01229;MGYG000002279_01057;MGYG000000184_01187;MGYG000000217_01269;MGYG000001637_00016;MGYG000000251_01816;MGYG000000312_01463;MGYG000000038_01591;MGYG000002670_00401;MGYG000000076_02823;MGYG000000242_01808;MGYG000000245_02653;MGYG000000271_01076;MGYG000002966_02560;MGYG000001496_03135;MGYG000002492_00390;MGYG000002366_00451;MGYG000000095_00559;MGYG000003821_00354;MGYG000000002_00867;MGYG000002415_02001;MGYG000000206_01049;MGYG000000179_04585;MGYG000000233_02358;MGYG000002477_00172;MGYG000000806_01297;MGYG000002502_01800;MGYG000002506_02946;MGYG000001970_02204;MGYG000002323_00401;MGYG000004519_01474;MGYG000002504_03949;MGYG000002836_03716;MGYG000004762_01319;MGYG000001615_01744;MGYG000001338_02792;MGYG000002286_01574;MGYG000001065_00455;MGYG000002202_01344;MGYG000001374_01181;MGYG000000255_01825;MGYG000000133_00060;MGYG000000216_02348 domain d__Bacteria 1.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,3XYVK@572511|Blautia 0.21739130434782608 186801|Clostridia 0.855072463768116 J 1.0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center 0.8695652173913043 rplF 1.0 - 0.855072463768116 - 1.0 ko:K02933 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573546 0 0 0 0 0 468626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)SLGEISDAVEK MGYG000000742_00316 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900541605|m__MGYG000000742 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H37I@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16437751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)SLGEISDAVEKVSGR MGYG000000742_00316 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900541605|m__MGYG000000742 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H37I@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1192713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)SVFDLSAEDFAK MGYG000000236_04341 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0149@1|root,COG2259@1|root,COG0149@2|Bacteria,COG2259@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia,4AVCD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 DoxX,MauE,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 728927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)SVGADCVAHGSTGAGNDQVR MGYG000000074_01979 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,2FMRA@200643|Bacteroidia,22UZN@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Arginosuccinate synthase 1.0 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Fluid shear stress and atherosclerosis;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1409434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)TGSAAYNQK MGYG000001415_01222 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)TSITIDGDNFNFYFEK MGYG000000198_05929 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,21ZAM@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9494996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)TSNLSLDER MGYG000000074_00675 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1409@1|root,COG1409@2|Bacteria,4PNR4@976|Bacteroidetes,2FZJW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Putative binding domain, N-terminal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BACON 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2642387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)TVEALGLK MGYG000001310_00105;MGYG000000194_02264;MGYG000000038_01594;MGYG000002835_00994;MGYG000001496_03138;MGYG000000249_01533;MGYG000001456.1_01734;MGYG000000146_01033;MGYG000002772_00339;MGYG000002528_01857;MGYG000000159_01029;MGYG000003324_00563;MGYG000000164_02746;MGYG000000262_00164;MGYG000002290_02006;MGYG000002279_01054;MGYG000001315_01354 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1841@1|root,COG1841@2|Bacteria,1TU6C@1239|Firmicutes,2588K@186801|Clostridia,3WM76@541000|Ruminococcaceae 0.17647058823529413 186801|Clostridia 0.8823529411764706 J 1.0 Ribosomal protein L30p/L7e 0.7058823529411765 rpmD 1.0 - 0.8823529411764706 - 1.0 ko:K02907 0.8235294117647058 ko03010,map03010 0.8235294117647058 M00178,M00179 0.8235294117647058 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.8235294117647058 - 1.0 - 1.0 - 1.0 Ribosomal_L30 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.8235294117647058 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1390955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)VADDIQAR MGYG000001658_01510;MGYG000002641_02426;MGYG000001300_01498;MGYG000000039_00844;MGYG000002224_01363;MGYG000002619_02323;MGYG000002098_00988;MGYG000000195_01879;MGYG000003166_00426;MGYG000000076_00689;MGYG000003291_00077;MGYG000000245_00548;MGYG000003899_02162;MGYG000002272_02091;MGYG000002545_02469;MGYG000002040_01179;MGYG000000201_01623;MGYG000000389_01654;MGYG000002517_01303;MGYG000002274_02019;MGYG000001255_01254;MGYG000002298_00512;MGYG000004733_01177 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 0.6956521739130435 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 0.8260869565217391 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 GH49 0.8695652173913043 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 658309 1460444 0 0 0 1377019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4011623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)VAGAATQSVADQEAIK MGYG000000054_01445 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides acidifaciens|m__MGYG000000054 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1537390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)VAGVDAYIVDLNEPATASGR MGYG000002171_02932 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002493165|m__MGYG000002171 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 535869 0 0 507341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 715712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)VAVVADDLAQESR MGYG000004642_00531;MGYG000004285_00367 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670 1.0 COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,36FZP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 2-hydroxyglutaryl-CoA dehydratase, D-component 1.0 - 1.0 - 1.0 1.3.7.8,4.2.1.54 1.0 ko:K04112,ko:K20627 1.0 ko00362,ko00640,ko00643,ko01100,ko01120,ko01220,map00362,map00640,map00643,map01100,map01120,map01220 1.0 M00541 1.0 R02451,R02963 1.0 RC00002,RC00818,RC01839 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HGD-D 1.0 - 1.0 - 1.0 - 1.0 - 1.0 benzoyl-CoA reductase. | lactoyl-CoA dehydratase. - Inactive toward aromatic acids that are not CoA esters but will also catalyze the reaction: NH3 + acceptor + 2 ADP + 2 phosphate = hydroxylamine + reduced acceptor + 2 ATP + H2O.-!-In the presence of reduced acceptor, but in the absence of oxidizable substrate, the enzyme catalyzes the hydrolysis of ATP to ADP plus phosphate.-!-Formerly EC 1.3.99.15. | A bacterial enzyme that is involved in propanoate fermentation (also known as the acrylate pathway). 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized 2[4Fe-4S]- [ferredoxin] + 2 phosphate = 2 ATP + benzoyl-CoA + 2 H2O + reduced 2[4Fe- 4S]-[ferredoxin]. | (R)-lactoyl-CoA = acryloyl-CoA + H2O. 1.0 1.0 1.0 1.0 Benzoate degradation;Metabolic pathways;Styrene degradation;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)VCVLEKEEDVC(Carbamidomethyl)C(Carbamidomethyl)GTSK MGYG000001379_01928;MGYG000000076_01007;MGYG000002279_02522;MGYG000000245_01076 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 0.75 186801|Clostridia 1.0 S 1.0 BFD-like [2Fe-2S] binding domain 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1806167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)VSAIDFLK MGYG000002528_01043 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0493@1|root,COG0493@2|Bacteria,1TR18@1239|Firmicutes,24A8Q@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 'oxidoreductase 1.0 - 1.0 - 1.0 1.3.1.1 1.0 ko:K17722 1.0 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 1.0 M00046 1.0 R00977,R01414,R11026 1.0 RC00072,RC00123 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4_20,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 dihydrouracil dehydrogenase (NAD(+)). - The enzyme was originally discovered in the uracil-fermenting bacterium, Clostridium uracilicum, which utilizes uracil and thymine as nitrogen and carbon sources for growth.-!-Since then the enzyme was found in additional organisms including Alcaligenes eutrophus, Pseudomonas strains and Escherichia coli. (1) 5,6-dihydrouracil + NAD(+) = H(+) + NADH + uracil. (2) 5,6-dihydrothymine + NAD(+) = H(+) + NADH + thymine. 1.0 1.0 1.0 1.0 Metabolic pathways;beta-Alanine metabolism;Pantothenate and CoA biosynthesis;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1274356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)VSWYDNEMSYTSQLVR MGYG000004789_01485 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Streptococcaceae|g__Streptococcus|s__Streptococcus sp001556435|m__MGYG000004789 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli 1.0 91061|Bacilli 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 GO:0000166,GO:0002020,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0019899,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)VTLSGPDGYIYDPDGITTK MGYG000000255_02227;MGYG000000233_02492 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,222GB@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 351470 0 0 443311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326910 0 0 0 0 0 0 408212 0 0 0 0 0 0 0 379001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2959082 0 1627454 2258158 0 1116975 0 0 2303375 0 0 0 0 0 0 0 0 0 0 0 0 1835699 0 1456292 0 2803898 3086107 0 2736966 0 0 2010633 1656439 3455961 2723624 2025178 2322934 1388963 6725857 4764455 0 5790083 0 5644337 0 0 6036079 0 3755066 0 0 0 0 0 0 0 0 5605677 0 6511032 0 4482835 0 4087266 5887239 0 0 0 0 0 5354318 6378595 5652272 6668848 0 3915985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)VYPAVQGQALK MGYG000000243_01886;MGYG000002171_01694 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 7791023 0 0 3451940 0 0 0 0 3577103 0 0 0 4245609 4637689 0 0 0 0 0 0 0 4942424 0 0 0 0 0 4022982 6589525 0 0 0 0 0 3946300 9311451 0 0 0 0 0 0 0 0 0 0 148896 0 0 0 0 0 0 0 0 0 0 268109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)YDVLEDGAFK MGYG000001602_00394 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia|s__Blautia sp900547685|m__MGYG000001602 1.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,3Y02G@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit 1.0 rpsH 1.0 - 1.0 - 1.0 ko:K02994 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 273922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 679771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2072337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)YGIPHISTGDIFR MGYG000000194_02261;MGYG000000479_01390;MGYG000001247_00924;MGYG000000077_00875;MGYG000004733_00989;MGYG000000216_02342;MGYG000000398_00972;MGYG000002989_00878;MGYG000001785_00490;MGYG000001577_00628;MGYG000002966_02554;MGYG000003012_01979;MGYG000001619_00813;MGYG000000135_01184;MGYG000000252_01798;MGYG000002298_00349;MGYG000001543_00396;MGYG000004697_01278;MGYG000002835_00997;MGYG000000002_00861;MGYG000003335_01412;MGYG000003821_00360;MGYG000000205_02183;MGYG000000171_01884;MGYG000004879_01576;MGYG000000274_01716;MGYG000000233_02364;MGYG000000206_01055;MGYG000001065_00449;MGYG000000133_00066;MGYG000000909_01226;MGYG000001315_01358;MGYG000000212_03068;MGYG000001199_01747;MGYG000001777_00253;MGYG000001793_01093;MGYG000000806_01303;MGYG000000690_01580;MGYG000000404_01617 domain d__Bacteria 1.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3XZAB@572511|Blautia 0.358974358974359 186801|Clostridia 0.9487179487179487 F 0.9743589743589743 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism 0.9743589743589743 adk 0.9743589743589743 - 1.0 2.7.4.3 0.9743589743589743 ko:K00939 0.9743589743589743 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 0.9743589743589743 M00049 0.9743589743589743 R00127,R01547,R11319 0.9743589743589743 RC00002 0.9743589743589743 ko00000,ko00001,ko00002,ko01000,ko04147 0.9743589743589743 - 1.0 - 1.0 iHN637.CLJU_RS20110 0.9230769230769231 ADK,ADK_lid 0.9743589743589743 - 1.0 - 1.0 - 1.0 - 1.0 adenylate kinase. myokinase. Inorganic triphosphate can also act as donor. AMP + ATP = 2 ADP. 0.9743589743589743 0.9743589743589743 0.9743589743589743 0.9743589743589743 Thiamine metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 0.9743589743589743 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)YIIAPEGIK MGYG000003683_01135;MGYG000000171_01902;MGYG000002395_00353;MGYG000000142_02064;MGYG000000200_01110;MGYG000002835_00979;MGYG000000002_00879;MGYG000003702_00697;MGYG000003452_00885;MGYG000000164_02761;MGYG000002459_00382;MGYG000001490_00323;MGYG000000756_00965;MGYG000000184_01175;MGYG000000133_00048;MGYG000001338_02804;MGYG000000127_02546 domain d__Bacteria 1.0 COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CZ5U@85004|Bifidobacteriales 0.35294117647058826 186801|Clostridia 0.6470588235294118 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 0.6470588235294118 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3165272 0 0 0 0 0 0 0 0 0 0 0 4862985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 887325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionamide)YSVVC(Carbamidomethyl)GSFGVK MGYG000003681_01674 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG3087@1|root,COG3087@2|Bacteria,4NU0A@976|Bacteroidetes,2FPJ1@200643|Bacteroidia,4AKB9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 D 1.0 Sporulation and cell division repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SPOR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1842646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1907062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl)ADGGSKDFATYDDDGAVYVQR MGYG000002445_02384 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp003024715|m__MGYG000002445 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3118726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl)AEDAAKTIGVGLQSFC(Carbamidomethyl)IPGSVADDR MGYG000000045_01847 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 2C4R5@1|root,2Z7JK@2|Bacteria 1.0 2|Bacteria 1.0 S 1.0 Psort location Cytoplasmic, score 1.0 BT0173 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl)ALVANGVFAVSEGANMPSTPEAIR MGYG000001789_00079;MGYG000003693_00557 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AKTV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 286742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1997307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl)ANDQPFIMPVEDVFSITGR MGYG000003324_00542 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Anaerovoracaceae|g__VUNA01|s__|m__MGYG000003324 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WCCR@538999|Clostridiales incertae sedis 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl)FDVLATDVLSSIDTALK MGYG000002494_03500 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,3X1YU@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 fliC 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl)GQNADLFIAGPAFNAGR MGYG000000146_02851 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea|s__Dorea formicigenerans|m__MGYG000000146 1.0 COG1978@1|root,COG1978@2|Bacteria,1TPAB@1239|Firmicutes,2487X@186801|Clostridia,27UY7@189330|Dorea 1.0 186801|Clostridia 1.0 S 1.0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) 1.0 grdB 1.0 - 1.0 1.21.4.2 1.0 ko:K10672 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 GRDB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2298119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2679575 0 0 0 0 3742324 0 0 0 0 0 0 0 0 0 0 0 0 0 2129681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl)LSAAEVETLLR MGYG000001415_00893 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,22UVQ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 232779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243625 0 0 0 0 0 0 0 0 0 0 268339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl)LVALIEASDAMVK MGYG000002494_04005;MGYG000002477_02044 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG4576@1|root,COG4577@1|root,COG4576@2|Bacteria,COG4577@2|Bacteria,1RIK4@1224|Proteobacteria,1S6GW@1236|Gammaproteobacteria,3ZNAY@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 CQ 1.0 Ethanolamine utilisation protein EutN/carboxysome 1.0 eutN 1.0 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 1.0 - 1.0 ko:K04028 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC,EutN_CcmL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl)LVAMNMMEGTLVQIR MGYG000002494_02689 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily 1.0 frdA 1.0 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.0 1.3.5.4 1.0 ko:K00244 1.0 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 1.0 M00009,M00011,M00150,M00173 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECIAI39_1322.ECIAI39_4621,iEcSMS35_1347.EcSMS35_4625,iPC815.YPO0360 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl)MLDAAGILTAR MGYG000002082_00584;MGYG000003279_00708;MGYG000000074_01177 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,22U5P@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 2186542 3386945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2703759 0 3194813 0 0 4067573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3131196 3119250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2995907 0 3582499 0 0 4712208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4496323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1891985 1773927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2097986 0 1207679 0 0 3075643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3343392 4060779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2965357 0 3408806 0 0 3978012 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl)PEIMLVGATAIGR MGYG000000312_02427;MGYG000000164_00688;MGYG000002492_00661;MGYG000002517_00544;MGYG000000245_02023;MGYG000002528_02669 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8333333333333334 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1157395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 504191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl)SEGYQDFLNGEVR MGYG000001310_00851 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 868902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl_13C(3))AGFAASQDLVGNTWTPEHTNAK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 526622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053620 0 0 0 1593827 0 0 0 711753 701878 0 0 0 882781 0 0 308889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343575 0 0 0 0 -(Propionyl_13C(3))AGFAASQDLVGNTWTPEHTNAKFPK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl_13C(3))AIETGVPK MGYG000002171_02052;MGYG000000243_02184;MGYG000002478_00340 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,4AMCS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Psort location Cytoplasmic, score 8.96 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1865603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl_13C(3))ANVELVGYEK MGYG000001065_00269 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp900538485|m__MGYG000001065 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,2235C@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 CQ 1.0 BMC domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl_13C(3))AVDYIMDKLAEK MGYG000002528_02668 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl_13C(3))DVVANADGQVIIGEVNQDATAQNIQQR MGYG000000200_00369 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp003471165|m__MGYG000000200 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 890754 0 0 0 0 858567 0 0 0 0 854555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 678125 0 0 0 0 0 0 0 0 0 1142555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 441163 0 0 0 0 0 0 0 0 0 320450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl_13C(3))DVVANADGQVVIGEVNQDATAQNIQQR MGYG000004733_00834;MGYG000000212_00952 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 548537 0 355644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propionyl_13C(3))LIDEFEKLEGR MGYG000000742_00316 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900541605|m__MGYG000000742 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H37I@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3934566 0 0 0 0 6356086 0 0 0 0 5614239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)AAFEEAEHAAK MGYG000003509_00509;MGYG000000177_00118;MGYG000002026_00456;MGYG000003891_00390;MGYG000004769_01404;MGYG000000198_03730;MGYG000000172_04155;MGYG000004087_01663;MGYG000001434_00926;MGYG000000198_03710;MGYG000004087_01662;MGYG000001564_01103;MGYG000001311_01511;MGYG000001493_02801;MGYG000001493_02800;MGYG000003422_00075;MGYG000004713_00792 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,21YU6@1506553|Lachnoclostridium 0.5294117647058824 186801|Clostridia 0.8823529411764706 C 1.0 Rubrerythrin 0.6470588235294118 rbr3A 0.9411764705882353 - 0.9411764705882353 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.8823529411764706 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2841248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)ADADIASDDAIKK MGYG000000212_00409 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG1879@1|root,COG1879@2|Bacteria,1TRBC@1239|Firmicutes,24DQX@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)ADAPQFNVGDTVK MGYG000004735_00305 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 - 1.0 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7100136 0 0 0 0 0 0 0 -(Propyl)AFADLDEDQQK MGYG000002218_01634 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides sp000436495|m__MGYG000002218 1.0 COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia,22Y6V@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Biopolymer transporter ExbD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ExbD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1270489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)AGFMGIPVPK MGYG000000404_01797;MGYG000000312_02425;MGYG000001814_02502 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,27K1G@186928|unclassified Lachnospiraceae 0.6666666666666666 186801|Clostridia 1.0 I 0.6666666666666666 Acyl-CoA dehydrogenase, C-terminal domain 0.6666666666666666 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 9890275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)AIDPAAMAK MGYG000001310_00280;MGYG000002772_01916;MGYG000000249_01751 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 0.6666666666666666 adh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 368333 163015 507096 349524 167575 514457 202036 190364 0 0 495300 0 0 220073 136364 507149 0 0 0 0 502878 549666 0 335236 723926 310631 490029 0 0 1062235 457675 459877 345868 742347 551287 254605 225362 281960 0 9524823 6366613 13631395 6444511 4651941 10782836 14840271 0 0 6615874 0 0 10882815 10109415 4787132 0 0 0 0 7211264 4374699 0 6313904 10462634 10596956 12788845 0 0 6856932 6187680 8596647 9496154 22777977 13627189 13534279 10347324 0 300177 665867 192847 505552 213534 171179 222273 366636 0 0 138401 0 0 165748 204978 278619 0 0 0 0 379764 363092 0 452416 257603 229014 388445 0 0 260994 351164 431082 195823 585118 202106 164837 0 272190 251236 0 353916 254489 616668 460585 420557 447012 0 0 623816 0 0 481391 811868 796131 0 0 0 0 798031 1122438 0 353041 795544 566613 809448 0 0 953873 802758 847309 797525 372720 915839 262522 331842 428022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1321727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1026160 0 -(Propyl)ALISIAHPDFR MGYG000000077_02473 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum soehngenii|m__MGYG000000077 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,25VHE@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 805758 548644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518904 465832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)ALTTKHER MGYG000000236_00435 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG1883@1|root,COG1883@2|Bacteria,4NH3V@976|Bacteroidetes,2FMSY@200643|Bacteroidia,4ANA7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 sodium ion-translocating decarboxylase, beta subunit 1.0 oadB 1.0 - 1.0 4.1.1.3 1.0 ko:K01572 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 OAD_beta 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)ASYGETGLDESAGR MGYG000002721_02202 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-873|s__CAG-873 sp009775195|m__MGYG000002721 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3175042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)ATVLGHIQR MGYG000002366_04608;MGYG000003394_01036;MGYG000001423_01186;MGYG000000337_02244;MGYG000002534_04706;MGYG000002504_03852;MGYG000002323_04064;MGYG000000093_04937;MGYG000002506_03612;MGYG000002494_01934 domain d__Bacteria 1.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,3XNE3@561|Escherichia 0.7 1236|Gammaproteobacteria 0.8 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 0.9 pfkA 1.0 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003872,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005945,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019200,GO:0019318,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035639,GO:0036094,GO:0042802,GO:0042866,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0061615,GO:0061695,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494,GO:1990234 0.8 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 iNRG857_1313.NRG857_19550 0.8 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1671804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)AVALEDEKIK MGYG000001496_02714 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Extibacter|s__Extibacter sp001185345|m__MGYG000001496 1.0 28HF7@1|root,2Z7RC@2|Bacteria,1TQET@1239|Firmicutes,249YW@186801|Clostridia,27V4K@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 Glycine/sarcosine/betaine reductase component B subunits 1.0 grdE 1.0 - 1.0 1.21.4.2 1.0 ko:K10671 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1742567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)AVPIQLPIGK MGYG000002926_00231 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,2N72W@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 728274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210525 0 0 0 0 0 0 0 0 0 0 114325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)AVVFINC(Carbamidomethyl)K MGYG000003510_00582 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__UBA6857|s__|m__MGYG000003510 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2529601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176096 0 0 0 0 0 0 0 0 -(Propyl)EADPELQIVAFKR MGYG000004797_01413;MGYG000002478_01739 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)GALLVGPPGTGK MGYG000001787_01446;MGYG000002478_02017;MGYG000000251_01096;MGYG000001675_00396;MGYG000004105_01889;MGYG000004006_00226;MGYG000002966_02777;MGYG000000364_01789;MGYG000004879_00637;MGYG000001310_01000;MGYG000000201_02976;MGYG000002171_01780;MGYG000002298_03713;MGYG000002528_01333;MGYG000002638_00844;MGYG000000142_01577;MGYG000001193_00690;MGYG000003149_00769;MGYG000001315_00392;MGYG000002540_02250;MGYG000001423_00451;MGYG000004414_00685;MGYG000001461_01641;MGYG000002247_02233;MGYG000001630_01353;MGYG000000121_03763;MGYG000000171_02296;MGYG000001338_00422;MGYG000001655_01521;MGYG000000216_00467;MGYG000002275_00331;MGYG000003486_02088;MGYG000004757_01506;MGYG000000484_01836;MGYG000003565_00613;MGYG000000042_00712;MGYG000002946_03966;MGYG000004899_01671;MGYG000000325_02475;MGYG000000255_02652;MGYG000000271_03460;MGYG000001789_00355;MGYG000000387_01574;MGYG000000223_03489;MGYG000000127_05497;MGYG000001804_00967;MGYG000002963_00296;MGYG000000201_02153;MGYG000000251_00277;MGYG000004703_01701;MGYG000002438_02722;MGYG000002082_00215;MGYG000004317_02215;MGYG000000154_01586;MGYG000004733_02060;MGYG000000198_00286;MGYG000000781_00218;MGYG000001617_00913;MGYG000004740_00938;MGYG000001567_00555;MGYG000002492_00620;MGYG000004464_01963;MGYG000002517_00481;MGYG000004891_02849;MGYG000003202_01226;MGYG000002772_00708;MGYG000003366_01210;MGYG000003367_00619;MGYG000000105_02204;MGYG000000138_02290;MGYG000001338_01442;MGYG000001606_02454;MGYG000002052_00044;MGYG000002875_00453;MGYG000000172_03039;MGYG000001503_01865;MGYG000002133_01352;MGYG000004885_00121;MGYG000000249_00927;MGYG000002989_01596;MGYG000000142_02465;MGYG000001783_02519;MGYG000000243_02615;MGYG000003984_01746;MGYG000001814_01099;MGYG000002614_00650;MGYG000003353_01906;MGYG000000153_02386;MGYG000000031_02902;MGYG000003821_01844;MGYG000001602_02233;MGYG000002279_00289;MGYG000000262_01668;MGYG000001378_03057;MGYG000000171_00202;MGYG000003460_01946;MGYG000002298_02917;MGYG000001370_01381;MGYG000003493_00456;MGYG000003546_00869;MGYG000003362_02047;MGYG000003702_02477;MGYG000000200_03319;MGYG000004271_00167;MGYG000000255_01996;MGYG000000205_00988;MGYG000000073_00731;MGYG000001623_03260;MGYG000003922_00970;MGYG000002042_00092;MGYG000001364_01334;MGYG000002033_00064;MGYG000000301_00550;MGYG000001489_00269;MGYG000003351_03543;MGYG000003215_00517;MGYG000004830_00142;MGYG000000245_01966;MGYG000002905_00935;MGYG000002218_00112;MGYG000000164_02134;MGYG000002155_00457;MGYG000000133_02963;MGYG000001570_01070 domain d__Bacteria 1.0 COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,2FNEA@200643|Bacteroidia,4AKUK@815|Bacteroidaceae 0.1532258064516129 186801|Clostridia 0.6129032258064516 O 1.0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins 1.0 ftsH 0.9919354838709677 - 1.0 - 1.0 ko:K03798 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000,ko01002,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,FtsH_ext,Peptidase_M41 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)GAVIPELDGK MGYG000004729_00235 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Anaerovoracaceae|g__Eubacterium_T|s__|m__MGYG000004729 1.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2WIK1@28221|Deltaproteobacteria,43S9H@69541|Desulfuromonadales 1.0 28221|Deltaproteobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gapA 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)GFIENVLR MGYG000000215_01440 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella stercorea|m__MGYG000000215 1.0 COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,2FMFC@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) 1.0 dapA 1.0 - 1.0 4.3.3.7 1.0 ko:K01714 1.0 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 1.0 M00016,M00525,M00526,M00527 1.0 R10147 1.0 RC03062,RC03063 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHDPS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-tetrahydrodipicolinate synthase. dihydrodipicolinate synthetase. The reaction can be divided into three consecutive steps: Schiff base formation with pyruvate, the addition of L-aspartate-semialdehyde, and finally transimination leading to cyclization with simultaneous dissociation of the product.-!-The product of the enzyme was initially thought to be (S)-2,3- dihydrodipicolinate, and the enzyme was classified accordingly as EC 4.2.1.52.-!-Later studies of the enzyme from the bacterium Escherichia coli have suggested that the actual product of the enzyme is (2S,4S)-4-hydroxy- 2,3,4,5-tetrahydrodipicolinate, and thus the enzyme has been reclassified as 4-hydroxy-tetrahydrodipicolinate synthase.-!-However, the identity of the product is still controversial, as more recently it has been suggested that it may be (S)-2,3- dihydrodipicolinate after all.-!-Formerly EC 4.2.1.52. L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5- tetrahydrodipicolinate + H(+) + H2O. 1.0 1.0 1.0 1.0 Monobactam biosynthesis;Metabolic pathways;Lysine biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4269351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)GTDIKLDEEAK MGYG000000198_05418 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,21YP5@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane 1.0 secA 1.0 - 1.0 - 1.0 ko:K03070 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 1.0 - 1.0 - 1.0 Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW 1.0 - 1.0 - 1.0 GT41 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 2074563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)LGTGDDQIVSAGFDAGSVIK MGYG000002772_00505 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__|m__MGYG000002772 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,36GVP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7810874 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8757830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)NAKYPTISQENGVQGK MGYG000000243_02206 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,2FPKW@200643|Bacteroidia,4AKHT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins 1.0 - 1.0 - 1.0 - 1.0 ko:K03832 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 2.C.1.1 1.0 - 1.0 - 1.0 TonB_C,VIT,VWA_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 519971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726763 0 0 0 0 0 0 0 0 0 0 0 0 0 1026979 0 0 0 0 0 0 0 401962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177879 0 0 -(Propyl)NAQESALK MGYG000000196_04532 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,4NEQV@976|Bacteroidetes,2FMXG@200643|Bacteroidia,4AMK8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG5016 Pyruvate oxaloacetate carboxyltransferase 1.0 cfiA 1.0 - 1.0 6.4.1.1 1.0 ko:K01960 1.0 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 1.0 M00173,M00620 1.0 R00344 1.0 RC00040,RC00367 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl,HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate carboxylase. pyruvic carboxylase. The animal enzyme requires acetyl-CoA. ATP + hydrogencarbonate + pyruvate = ADP + H(+) + oxaloacetate + phosphate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5070408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)QALENIK MGYG000000953_00047;MGYG000002485_00024 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0049@1|root,COG0049@2|Bacteria,3790N@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2650985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)QGILTVSLK MGYG000003482_02091 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Selenomonas_C|s__Selenomonas_C bovis|m__MGYG000003482 1.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4H4AT@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit 1.0 rpsH 1.0 - 1.0 - 1.0 ko:K02994 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2907225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)SGMTPKFINGLR MGYG000000127_03225 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Catenibacillus|s__Catenibacillus sp902363555|m__MGYG000000127 1.0 COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the acetylglutamate kinase family. ArgB subfamily 1.0 argB 1.0 - 1.0 2.7.2.8 1.0 ko:K00930 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028 1.0 R02649 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AA_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetylglutamate kinase. - - ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 919258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)TATADQAEEVC(Carbamidomethyl)AAIR MGYG000003921_00579;MGYG000003937_01848;MGYG000001157_01821 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 830697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459347 0 0 0 0 394352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 445143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)TGIQITKAANDDLLNSFWLLDSEKGEAR MGYG000002506_02099 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG3445@1|root,COG3445@2|Bacteria,1RDRB@1224|Proteobacteria,1S45G@1236|Gammaproteobacteria,3XPJB@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Acts as a radical domain for damaged PFL and possibly other radical proteins 1.0 grcA 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.0 - 1.0 ko:K06866 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 iSF_1195.SF2641,iSFxv_1172.SFxv_2898,iS_1188.S2814 1.0 Gly_radical 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl)VGATAADIGAIGITNQR MGYG000002517_00259 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 1372913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 957237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1865310 -(Propyl_2H(6))EVLGGTVSC(Carbamidomethyl)SR MGYG000000271_02100;MGYG000000389_02147;MGYG000002517_00544;MGYG000000154_01280;MGYG000004697_01805;MGYG000000076_01277;MGYG000003486_02520 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.7142857142857143 etfA 1.0 - 0.8571428571428571 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23734632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Propyl_2H(6))GFEMEYQVDPLR MGYG000004479_02858 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola mediterraneensis|m__MGYG000004479 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,4AKE4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 738729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466551 0 0 0 0 576931 0 0 475592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 499474 0 0 0 0 945141 0 0 5141385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4470009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 861755 0 0 0 0 0 -(Propyl_2H(6))QMFGAEGFEIVAINDLTSPK MGYG000000301_01012;MGYG000000212_01474;MGYG000000171_00850;MGYG000000002_02120;MGYG000002212_00259;MGYG000002966_00075;MGYG000001338_02547;MGYG000000133_02283;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000001315_01699;MGYG000003702_00925;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(PyMIC)IEDAKAEIAR MGYG000000271_02507;MGYG000004271_00779 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9,2.7.9.2 1.0 ko:K01007,ko:K08483 1.0 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060 1.0 M00173,M00374 1.0 R00199 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--protein phosphotransferase. | pyruvate, water dikinase. sugar--PEP phosphotransferase enzyme I. | pyruvate,water dikinase. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. | ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Phosphotransferase system (PTS);Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(PyMIC)MLLDAMENPEKYPQLTIR MGYG000002506_00229 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1RM96@1236|Gammaproteobacteria,3XMX2@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 formate C-acetyltransferase activity 1.0 pflB 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECH74115_1262.ECH74115_1064,iECIAI39_1322.ECIAI39_2245,iECSP_1301.ECSP_1007,iECs_1301.ECs0986,iEcSMS35_1347.EcSMS35_2218,iG2583_1286.G2583_1138,iSDY_1059.SDY_2358,iZ_1308.Z1248 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyridylacetyl[AnyN-term](Phenylisocyanate)TLDSYIPEPER MGYG000001485_02164 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Pseudomonadales|f__Pseudomonadaceae|g__Pseudomonas_E|s__Pseudomonas_E massiliensis|m__MGYG000001485 1.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1YM7S@136843|Pseudomonas fluorescens group 1.0 1236|Gammaproteobacteria 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1783163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyridylacetyl[AnyN-term](Phenylisocyanate)TVIPEDVR MGYG000000243_02364 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,4AKHK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2028623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyridylacetyl[AnyN-term](Phenylisocyanate)VAAALEEGK MGYG000000484_01539 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A sp000431815|m__MGYG000000484 1.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,4BWIF@830|Butyrivibrio 1.0 186801|Clostridia 1.0 EH 1.0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 1.0 pdxB 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C,ACT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3768331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyridylacetyl[AnyN-term](Phenylisocyanate)VSIVDLR MGYG000000142_01784;MGYG000000077_01492;MGYG000000262_00348;MGYG000000184_01361;MGYG000001642_01325 domain d__Bacteria 1.0 COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,25WBX@186806|Eubacteriaceae 0.4 186801|Clostridia 0.8 L 0.4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA 0.4 priA 0.4 - 1.0 - 1.0 ko:K04066 0.4 - 0.6 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03400 0.4 - 1.0 - 1.0 - 1.0 DEAD,Helicase_C,ResIII 0.4 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.6 none 1.0 0 1207862 0 0 0 0 0 0 0 0 0 0 588640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyridylacetyl[AnyN-term](Phenylisocyanate)VSLVDLR MGYG000000262_00348 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,25WBX@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 csoS1C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 586973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyridylacetyl[AnyN-term](Phenylisocyanate)VVVTMGPPPAEGMLR MGYG000002040_01718;MGYG000003899_01133;MGYG000000084_00626;MGYG000001300_00292;MGYG000003166_01337;MGYG000004732_01391;MGYG000004866_01547;MGYG000003937_01088;MGYG000002274_00048 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WH8V@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 4396017 0 0 0 0 0 0 5761775 0 0 0 2554834 4140889 0 0 0 0 3706117 0 4416021 0 0 0 0 0 5605245 0 0 0 0 0 0 5173204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1749743 0 0 0 0 2263383 0 0 0 0 0 0 2108659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516166 0 0 0 0 0 0 0 0 0 0 0 573089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 730985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CADAVKEYGIK MGYG000002515_03180;MGYG000002323_00409;MGYG000002506_02938;MGYG000002477_00164 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,3WY9K@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 890125 0 0 1200961 0 0 0 1008005 0 0 0 859081 0 0 0 0 0 0 0 1092931 0 1427241 0 0 503228 0 0 1006585 0 0 721700 860088 0 0 0 1041384 0 0 1172596 0 0 1913860 0 0 0 1548050 0 0 0 837495 0 0 0 0 0 0 0 2156432 0 1534347 0 0 939492 0 0 1036824 0 0 1359804 828931 0 0 0 1047142 0 0 1257958 0 0 1597167 0 0 0 932651 0 0 0 1017181 0 0 0 0 0 0 0 1710205 0 1220317 0 0 922461 0 0 775965 0 0 966788 944233 0 0 0 746253 0 0 1117479 0 0 1695155 0 0 0 1285702 0 0 0 693863 0 0 0 0 0 0 0 1148397 0 712022 0 0 982278 0 0 1169870 0 0 1177034 1800907 0 0 0 393795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257076 0 0 435340 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CADLHEFNPMMGHR MGYG000000198_00250 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,21XUV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 778350 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 979359 0 0 0 0 0 773950 0 0 0 0 0 0 0 0 0 660112 545702 0 247541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280274 0 0 0 0 0 376826 0 0 0 0 0 0 0 0 0 316894 302108 0 948782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 671808 0 0 0 0 0 708153 0 0 0 0 0 0 0 0 0 534937 709409 0 215539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293111 0 0 0 0 0 96855 0 0 0 0 0 0 0 0 0 323977 290495 0 -(Pyro-carbamidomethyl)CADYVLKDNPDVIR MGYG000000271_02809;MGYG000004271_01538 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CAELHEFNPMMGHR MGYG000000179_00100;MGYG000001646_00500;MGYG000002139_00077 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,21XUV@1506553|Lachnoclostridium 0.3333333333333333 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.6666666666666666 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 227142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423945 0 0 0 0 0 0 0 0 0 0 0 0 264363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242244 0 0 0 0 0 0 0 0 0 0 0 0 2151822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3503319 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CAEYALSR MGYG000002619_01801;MGYG000001300_02848;MGYG000002641_01266 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0152@1|root,COG0152@2|Bacteria,1VTBC@1239|Firmicutes,24ZTC@186801|Clostridia,3WH16@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 1.0 F 1.0 Belongs to the SAICAR synthetase family 0.6666666666666666 purC 1.0 - 1.0 6.3.2.6 1.0 ko:K01923 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04591 1.0 RC00064,RC00162 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 SAICAR_synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase. SAICAR synthetase. Forms part of the purine biosynthesis pathway. 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate + ADP + 2 H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110289 0 0 0 0 0 0 0 321655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CAHANEILQR MGYG000001345_03240;MGYG000000196_03771 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia,4AKWQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 1.0 rprY 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Response_reg,Trans_reg_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 589501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 669278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CAQVAQC(Carbamidomethyl)YK MGYG000000089_02197 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2415468 0 0 0 0 2353698 0 0 0 0 3288487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CATSDKASAELK MGYG000002517_00959;MGYG000000389_00578 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 208027 716691 457769 0 0 0 0 0 0 0 733923 0 0 819890 863934 0 0 0 680688 0 0 0 0 449788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182102 311384 0 0 0 0 0 0 0 0 0 0 226189 0 0 0 0 473659 0 0 0 0 512248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2267052 5715399 5940644 0 0 0 0 0 0 0 3609395 0 0 4265264 2571463 0 0 0 6010436 0 0 0 0 3922222 1702437 0 0 0 0 0 0 0 0 0 0 0 0 0 1955227 1539437 2457050 0 0 0 0 0 0 0 3100822 0 0 1931364 2050078 0 0 0 3089655 0 0 0 0 1452789 2726326 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CAYGWAKED MGYG000000164_01754 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 1511690 0 0 0 0 746515 0 0 0 0 0 0 0 0 0 0 0 0 0 1935690 0 964599 0 367188 0 2036310 0 0 0 0 0 0 0 0 1627444 0 1318897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CAYTPDKK MGYG000002517_01658 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 781303 0 491130 0 900708 774902 348032 0 605937 1053715 363942 722952 0 0 861541 0 755585 0 1091382 731667 922198 760160 0 725282 772767 567631 817005 0 0 726654 304999 0 412562 770395 0 0 759170 456423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321070 0 0 0 0 0 0 0 276872 430103 0 0 0 0 475480 0 162719 0 501634 434786 0 140473 0 0 395820 634468 511681 0 0 392251 0 0 0 0 0 0 624165 0 4564639 0 896627 0 3087801 1780552 2602693 0 6622574 2716157 1866450 2929694 0 0 6515226 0 4296570 0 4825870 4717498 2610039 389185 0 383917 6595199 5547317 5469917 0 0 4455275 1334935 0 1126005 3195282 0 0 5946141 934215 2511973 0 3693706 0 2288361 3268517 3169371 0 2824972 4336355 3981083 3444730 0 0 3123655 0 3594784 0 3544245 2088569 3666097 3187763 0 3286451 5226864 4247083 3680047 0 0 2249602 2710143 0 4040405 3537036 0 0 5813499 4011141 -(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHAAIRPF MGYG000001920_00369 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900546355|m__MGYG000001920 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1162620 0 0 0 0 802280 0 0 0 0 1532841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHAAIRPV MGYG000002298_00647;MGYG000001315_01946;MGYG000000031_03215 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3XZ4K@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHAAIRPVALTEEELAKAPEGLK MGYG000001315_01946 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,27VFG@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHASIRPF MGYG000001345_00428;MGYG000000196_04414;MGYG000002033_00365;MGYG000000013_01171;MGYG000002549_02787;MGYG000000138_01901;MGYG000000029_01835;MGYG000002540_01631;MGYG000002455_00144;MGYG000001780_02881;MGYG000003681_00938;MGYG000001346_02526;MGYG000003363_02878;MGYG000001337_03683;MGYG000001313_00862;MGYG000004899_00334;MGYG000002478_04117;MGYG000001666_02224;MGYG000000236_00388;MGYG000000243_00095;MGYG000004763_00186;MGYG000002438_04196 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 0.8181818181818182 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 1340173 0 2010835 0 2047239 1162736 0 1715113 1286487 0 2793476 0 1676186 1692493 1890145 1843789 0 0 1791846 0 0 803696 0 975538 0 1404099 1120195 0 1306457 1253042 0 0 1514251 1422095 1276344 0 1069632 1588946 479259 0 600293 0 586271 730476 0 927319 721927 0 635469 0 526499 557427 737325 541898 0 0 514180 0 0 631140 0 0 0 794167 922946 0 685111 574476 0 0 378402 712327 937472 0 470399 636321 0 0 610781 0 484026 0 0 493076 0 0 467452 0 0 0 0 539974 0 0 0 0 0 0 0 0 0 0 0 0 260934 1156441 0 0 0 0 0 0 586530 484537 1510523 0 1883658 0 1978122 2088508 0 1692808 1381177 0 2041403 0 2106300 1651362 1649605 2360564 0 0 1596604 0 0 1684372 0 1742473 0 1513562 1625973 0 1349414 1543801 0 0 1367307 1440920 1986992 0 1439852 1520313 401582 0 0 0 470484 0 0 426153 601580 0 367200 0 616586 444406 448282 777386 0 0 543801 0 0 666002 0 687063 0 0 584763 0 0 335969 0 0 0 812964 514384 0 0 655918 -(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHASIRPFVLDAEEQK MGYG000001345_00428;MGYG000000196_04414;MGYG000002561_01024;MGYG000000013_01171;MGYG000001461_03964;MGYG000002549_02787;MGYG000000029_01835;MGYG000002455_00144;MGYG000001780_02881;MGYG000003681_00938;MGYG000001346_02526;MGYG000001337_03683;MGYG000001313_00862;MGYG000004899_00334;MGYG000002478_04117;MGYG000000236_00388;MGYG000000243_00095 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 2030102 1890434 2465395 0 1911877 1885542 0 2694847 0 0 3364054 2662096 0 2348038 0 3123768 2164002 1628163 1739843 1603675 0 1886198 1885258 2280436 1806741 2226876 2556018 1509760 3008937 0 2977698 2191038 2811130 0 2147713 3165241 1960024 2499254 2147419 1498380 2350267 0 2764341 3136175 0 3232925 0 0 3912292 3479919 0 3277605 0 4070064 2585267 0 2559973 2385390 0 2713206 2051674 1773478 3303296 3377262 2450029 1120672 1979230 0 1883194 2663150 2098086 0 2397160 2741616 2973026 2052975 2009260 1199554 2323196 0 2966702 2365295 0 1583005 0 0 4383181 2995617 0 2060614 0 2800591 1816159 4143123 1726012 1469896 0 1520128 3262223 2372159 2078243 1964404 1710192 3096681 2046355 0 2880507 1551141 1499316 0 1943054 2802343 1975411 2453815 478677 336756 485024 0 394633 294343 0 484774 0 0 733137 747722 0 720123 0 276661 427180 0 560788 496835 0 282545 603703 0 844212 975131 796499 0 218068 0 355365 893454 256859 0 709744 858275 326322 335888 1484881 1173375 594762 0 2435096 1886159 0 1923120 0 0 3566517 1500104 0 1297237 0 1995356 1502428 5006073 1451043 1957663 0 2365704 4570755 1862552 1824980 1718653 1583576 3617850 1904644 0 1708248 1410969 1158431 0 1821904 1288753 1520659 1519066 -(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHAVIRPV MGYG000002989_02129;MGYG000000249_01618;MGYG000001602_02095;MGYG000000133_02129;MGYG000002279_02008;MGYG000000038_01290;MGYG000001496_03305;MGYG000001710_03430;MGYG000000164_01756;MGYG000001338_02036;MGYG000000002_01844;MGYG000002945_01470;MGYG000001310_00851;MGYG000001374_00733 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 0.35714285714285715 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 715116 0 0 957365 0 0 0 0 1290407 0 0 0 1237681 0 0 0 0 1048848 0 811325 0 0 0 0 0 0 0 269821 0 1323105 0 0 0 0 0 614023 0 0 530793 0 0 504862 0 0 0 0 344969 0 0 0 392454 0 0 0 0 401547 0 345511 0 339633 0 0 0 0 0 621877 0 1034514 481179 0 0 0 0 278230 0 0 273477 0 0 549817 0 0 0 0 0 0 0 0 396899 0 0 0 0 337957 0 0 0 443306 0 0 0 0 0 0 0 903237 628257 0 0 0 0 0 0 0 1353810 0 0 607282 0 0 0 0 829567 0 0 0 0 0 0 0 0 534058 0 1073770 0 650998 0 0 0 0 0 782034 0 2110155 1056675 0 0 0 0 1053609 0 0 957021 0 0 678728 0 0 0 0 682622 0 0 0 529830 0 0 0 0 230890 0 749061 0 644492 0 0 0 0 0 0 0 3786853 1452297 0 0 0 0 0 -(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHAVIRPVALTAEEAANAPEGMK MGYG000001338_02036;MGYG000000200_00183 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2210021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDAYAEHWAPK MGYG000001338_03293 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Radical SAM domain protein 1.0 atsB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,Radical_SAM,SPASM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 533111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432713 0 0 0 0 0 0 0 1526639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1306850 475147 0 0 0 0 0 0 0 782316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588577 0 0 0 0 0 0 0 647851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 794617 247711 0 0 0 0 0 0 0 643601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 574805 548441 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDC(Carbamidomethyl)GEQLHK MGYG000004763_02275;MGYG000002935_02168;MGYG000000003_02146;MGYG000000243_01797;MGYG000003279_01847;MGYG000002171_02994;MGYG000002478_00161;MGYG000002549_04025 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,2FNS0@200643|Bacteroidia,4AN9P@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 H 1.0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate 1.0 ribBA 0.75 - 1.0 3.5.4.25,4.1.99.12 1.0 ko:K14652 1.0 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 1.0 M00125,M00840 1.0 R00425,R07281 1.0 RC00293,RC01792,RC01815,RC02504 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHBP_synthase,GTP_cyclohydro2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GTP cyclohydrolase II. | 3,4-dihydroxy-2-butanone-4-phosphate synthase. guanosine triphosphate cyclohydrolase II. | L-3,4-dihydroxybutan-2-one-4-phosphate synthase. The enzyme, found in prokaryotes and some eukaryotes, hydrolytically cleaves the C-N bond at positions 8 and 9 of GTP guanine, followed by a subsequent hydrolytic attack at the base, which liberates formate, and cleavage of the alpha-beta phosphodiester bond of the triphosphate to form diphosphate.-!-The enzyme continues with a slow cleavage of the diphosphate to form two phosphate ions.-!-The enzyme requires zinc and magnesium ions for the cleavage reactions at the GTP guanine and triphosphate sites, respectively.-!-It is one of the enzymes required for flavin biosynthesis in many bacterial species, lower eukaryotes, and plants. cf. EC 3.5.4.16, EC 3.5.4.29, and EC 3.5.4.39. | The reaction involves an intramolecular skeletal rearrangement, with the bonds in D-ribulose 5-phosphate that connect C-3 and C-5 to C-4 being broken, C-4 being removed as formate and reconnection of C-3 and C-5.-!-The phosphorylated four-carbon product (L-3,4-dihydroxybutan-2-one 4-phosphate) is an intermediate in the biosynthesis of riboflavin. GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H(+) + 2 phosphate. | D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+). 1.0 1.0 1.0 1.0 Folate biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Riboflavin metabolism 1.0 none 1.0 853249 0 1205793 0 1163447 0 0 0 0 0 0 0 1025123 0 0 1117753 0 0 0 0 0 0 0 0 0 677554 0 0 0 0 0 0 1051640 0 0 0 847541 1140965 629036 0 728998 0 795769 0 0 0 0 0 0 0 765757 0 0 782859 0 0 0 0 0 0 0 0 0 755101 0 0 0 0 0 0 623045 0 0 0 690495 735314 624479 0 861762 0 1017967 0 0 0 0 0 0 0 815784 0 0 650825 0 0 0 0 0 0 0 0 0 700717 0 0 0 0 0 0 584179 0 0 0 630164 777971 364325 0 228787 0 255149 0 0 0 0 0 0 0 413389 0 0 254405 0 0 0 0 0 0 0 0 0 533598 0 0 0 0 0 0 345437 0 0 0 512071 0 476058 0 280949 0 719349 0 0 0 0 0 0 0 905534 0 0 582665 0 0 0 0 0 0 0 0 0 533038 0 0 0 0 0 0 374621 0 0 0 603571 360879 -(Pyro-carbamidomethyl)CDEMEQAKVK MGYG000000243_01586 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0AS@200643|Bacteroidia,4AMX1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MbeB_N,TPR_1,TPR_11,TPR_16,TPR_17,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1755067 0 1001328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1754597 0 0 0 0 1599333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359899 0 146845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDFNVPLK MGYG000002492_01380;MGYG000004552_00730;MGYG000000989_01451;MGYG000000262_01196;MGYG000003486_02012;MGYG000003628_01098;MGYG000000325_00585;MGYG000002854_00823;MGYG000000909_00645;MGYG000003684_03801;MGYG000001707_00062;MGYG000000193_03246;MGYG000000118_02693;MGYG000002528_00366;MGYG000004667_02165;MGYG000000181_00012;MGYG000001814_01254;MGYG000002946_02880;MGYG000000404_00343;MGYG000002966_00074;MGYG000004271_00555;MGYG000004087_02289;MGYG000001553_02341;MGYG000000233_00344;MGYG000000198_04064;MGYG000000359_00927;MGYG000002445_01919;MGYG000002989_02172;MGYG000001479_00351;MGYG000000301_01011;MGYG000000258_00429;MGYG000001186_01924;MGYG000001199_01004;MGYG000000076_03636;MGYG000000255_01167;MGYG000000154_00118;MGYG000000312_01507;MGYG000000204_00777;MGYG000000378_01265;MGYG000004740_01467;MGYG000004519_00424;MGYG000002517_01027;MGYG000000179_02085;MGYG000000087_02748;MGYG000001617_03190;MGYG000000245_03070;MGYG000001423_00990;MGYG000002670_00852;MGYG000001619_01735;MGYG000001683_01828;MGYG000000383_00714;MGYG000000271_03251;MGYG000004863_01610;MGYG000001493_05256;MGYG000000133_02282;MGYG000004735_01945;MGYG000000489_00504;MGYG000002289_02222 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 0.43103448275862066 186801|Clostridia 1.0 F 0.8620689655172413 Belongs to the phosphoglycerate kinase family 0.6379310344827587 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 267720 0 0 290103 0 71394 92272 102266 236474 207630 0 145871 0 208621 317437 85672 0 0 89859 183845 247527 190160 0 64662 101304 255378 71448 0 0 0 0 0 0 193914 0 279199 231582 0 144301 46528 0 139802 0 0 162107 68255 159529 145657 0 157961 0 64833 112774 0 0 0 157592 92498 0 0 0 0 0 141825 92226 0 0 0 0 0 59822 0 0 54669 59141 0 292109 0 59443 273017 0 90777 192004 143815 67561 189160 0 175309 0 272710 316000 184354 0 0 214788 140624 276629 128273 0 101102 226365 251332 212492 0 0 0 0 0 83925 175737 0 176957 221771 0 701033 127062 281457 561132 0 246630 410048 508412 595958 218290 0 343543 0 826132 674538 83867 0 0 495788 770147 522593 54050 0 82832 463640 492761 525745 0 0 0 0 0 242106 606167 0 762148 960690 215092 1262542 648218 872922 493046 0 826609 1216371 1069799 1094199 1213865 0 803561 0 1028562 1395063 877624 0 0 1432758 997222 985511 880281 0 634939 1139670 980658 907642 0 0 0 0 0 692422 1216467 0 854585 701035 631819 -(Pyro-carbamidomethyl)CDFNVPLKDGK MGYG000001186_01924;MGYG000000245_03070;MGYG000002670_00852;MGYG000001619_01735;MGYG000002492_01380;MGYG000004740_01467;MGYG000000271_03251;MGYG000000262_01196;MGYG000000404_00343;MGYG000004271_00555;MGYG000004519_00424;MGYG000000325_00585;MGYG000000233_00344;MGYG000000909_00645;MGYG000001141_01007;MGYG000000193_03246 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 0.6875 186801|Clostridia 1.0 F 0.8125 Belongs to the phosphoglycerate kinase family 0.75 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1635393 1494016 887899 2188640 1281483 1437967 1957109 1739353 1822713 2004258 2450647 0 1719525 1523252 0 1648961 1926478 1397183 1221834 1641924 0 1707896 730853 1109690 2105785 1515595 1677134 862425 1394503 0 776943 0 967135 2231618 1373876 1649232 1564983 555980 2531796 1918174 2000783 2560429 2626148 1567152 2541452 2240900 2012781 2131329 2597612 0 2512586 1834187 0 1843067 2038813 5033172 1767912 2075519 0 1367643 3154233 1782917 2174168 1911600 1965924 4430369 2319936 0 1492470 0 2019998 2329356 2308826 2361943 1783404 2044105 2339828 1798525 4244967 3120875 1440287 1579681 1345674 2573666 1511765 1830935 2221243 0 2414253 1995282 0 3082603 2126296 1451005 2126304 2010957 0 2216496 2564119 1112117 2354680 2190570 2567084 3429103 1256014 0 1320059 0 4038744 2928958 2572446 1459454 1965836 4845427 483358 593285 432490 846360 569940 602375 803326 636188 464375 586034 568675 0 577139 512003 0 841163 789169 519032 408264 752101 0 353930 0 679362 478029 341230 653035 411384 745604 0 539699 0 560701 413493 541972 487409 422408 495289 1668329 1281113 1106205 1005457 774068 1344120 2209767 1543647 1656737 1477360 1097334 0 896035 853625 0 1045743 1452256 1267289 1831579 1897657 0 701801 1591093 1183146 1529734 1435072 1309783 1809643 1355188 0 1071406 0 1282247 1900576 1313663 1332167 1580687 1168242 -(Pyro-carbamidomethyl)CDFNVPLKDGKITDENR MGYG000000271_03251;MGYG000000404_00343;MGYG000000262_01196;MGYG000004271_00555;MGYG000002670_00852;MGYG000002492_01380;MGYG000001141_01007;MGYG000004740_01467 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 0.5 186801|Clostridia 1.0 F 0.75 Belongs to the phosphoglycerate kinase family 0.625 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDFNVPLKDGQITDENR MGYG000002528_00366;MGYG000000118_02693 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3XYK6@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 425961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1815829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDFNVPLKEGK MGYG000000301_01011;MGYG000001617_03190;MGYG000001199_01004;MGYG000000133_02282;MGYG000000181_00012;MGYG000000076_03636;MGYG000000154_00118;MGYG000002445_01919;MGYG000001707_00062 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3XYK6@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 0.5555555555555556 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 488351 0 0 0 422270 0 0 380863 0 0 0 506900 0 0 0 547635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 737380 0 0 0 0 0 744001 0 0 0 0 1255475 1011917 646724 701521 951757 0 0 696048 0 676152 0 0 0 1057741 871455 885539 0 0 0 0 0 0 0 0 0 753338 0 0 0 0 0 0 0 0 0 0 264714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5812202 0 6663259 9241415 0 3600909 7966056 0 0 8225071 5679005 5284605 4598155 7959586 5610581 4052405 5533501 0 5640857 0 7492416 2949381 0 2802251 4561146 3830277 6289761 0 0 0 0 0 10976102 0 0 4955674 3098803 4670060 -(Pyro-carbamidomethyl)CDFNVPLKEGVIQNYNR MGYG000004087_02289;MGYG000000198_04064;MGYG000000179_02085;MGYG000002946_02880 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,21XSB@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Phosphoglycerate kinase 1.0 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 500551 0 0 0 0 0 0 461436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261473 362430 0 0 0 0 0 0 0 0 0 0 0 0 0 267970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114327 0 0 0 0 240574 0 0 0 0 0 0 0 0 0 490573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457652 974591 0 0 0 243122 0 0 197003 0 0 0 0 0 0 67674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363778 0 0 0 0 0 0 777428 0 0 0 0 0 0 1300245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1405195 1687205 0 0 0 1034807 -(Pyro-carbamidomethyl)CDFNVPLKNGEITDETR MGYG000003486_02012;MGYG000002517_01027;MGYG000000255_01167;MGYG000001814_01254;MGYG000002989_02172 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 0.8 186801|Clostridia 1.0 F 0.8 Belongs to the phosphoglycerate kinase family 0.8 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 438542 0 0 1038103 531367 0 0 0 0 1061792 0 0 0 0 764050 585648 1207985 0 0 883755 0 0 0 0 863185 789255 0 0 0 0 0 0 0 0 0 867042 947599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480570 0 0 0 0 0 346016 0 0 0 0 455178 0 0 0 0 0 0 0 0 0 417448 569377 0 0 0 0 0 0 0 0 0 599357 614280 0 2639783 0 0 3671224 1341769 0 0 0 0 1475402 0 1974294 0 0 3778300 1260422 2169580 0 0 2849356 0 0 0 0 3455939 3093505 0 0 0 0 0 0 0 0 0 3344550 3429087 0 2668899 0 0 0 2176550 0 0 0 0 4144301 0 2699328 0 0 4177120 2250479 3725626 0 0 2533444 0 0 0 0 4275823 3948290 0 0 0 0 0 0 0 0 0 4517391 5410455 0 -(Pyro-carbamidomethyl)CDFNVPLQDGK MGYG000000080_03114;MGYG000000212_01475;MGYG000000171_00851;MGYG000000139_00882;MGYG000000200_02456;MGYG000001714_01797;MGYG000000125_00366;MGYG000000249_01353;MGYG000001338_02546;MGYG000000002_02119;MGYG000001543_00857;MGYG000000050_00594;MGYG000002298_02411;MGYG000000806_01931;MGYG000000263_01340;MGYG000000252_01325;MGYG000000142_01978 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H2GV@909932|Negativicutes 0.6470588235294118 909932|Negativicutes 0.6470588235294118 G 0.7647058823529411 Belongs to the phosphoglycerate kinase family 0.7647058823529411 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 546048 1033486 838531 0 688651 913810 0 756177 0 0 1292367 0 0 0 0 0 499931 749524 0 204793 0 1340362 535565 0 0 378599 391657 948801 1020326 0 0 790403 443373 301436 0 311796 182935 531364 524212 1623278 450166 0 1237787 492572 0 1119046 548978 0 758819 0 0 0 0 0 1003501 1728047 0 1061872 0 0 812898 633450 0 708923 778927 1396358 1210959 0 2406400 1309434 511216 676349 0 671870 492268 249111 197512 1196050 376075 0 0 339692 0 359615 204022 0 254938 0 0 0 0 0 563801 201403 0 349288 0 700774 538205 164613 0 692025 392094 718402 258577 0 421503 1210942 562271 485410 0 321235 287622 467919 0 1289885 0 0 655145 0 0 0 206493 0 316480 0 0 0 0 0 215714 0 0 204507 0 0 0 222172 0 0 189858 0 805727 0 1012353 815538 0 0 0 248558 0 600839 321253 1511306 1178506 0 0 605114 0 424491 219512 0 575263 0 0 0 0 0 289975 316393 0 0 0 135690 622467 573207 0 163853 404723 959219 1163684 0 859365 1132887 2091440 398920 0 443827 172829 779171 -(Pyro-carbamidomethyl)CDFNVPLQDGKITDENR MGYG000001338_02546;MGYG000000080_03114;MGYG000000212_01475;MGYG000000171_00851;MGYG000000002_02119;MGYG000000139_00882;MGYG000000050_00594;MGYG000002298_02411;MGYG000000200_02456;MGYG000001714_01797;MGYG000000142_01978 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H2GV@909932|Negativicutes 0.7272727272727273 909932|Negativicutes 0.7272727272727273 G 0.9090909090909091 Belongs to the phosphoglycerate kinase family 0.8181818181818182 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 552386 0 0 868671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1427524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 627018 0 0 454367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDFNVPMK MGYG000001255_00368;MGYG000001300_02037;MGYG000004221_01544;MGYG000002274_01739;MGYG000000022_00457;MGYG000003937_01847;MGYG000003921_00578;MGYG000002105_00517;MGYG000000084_00216;MGYG000003899_01395;MGYG000002641_00592;MGYG000002098_01090;MGYG000002040_00807 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae 0.9230769230769231 186801|Clostridia 1.0 G 0.9230769230769231 Phosphoglycerate kinase 0.9230769230769231 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189131 0 0 0 276146 0 0 0 0 0 0 342259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161387 0 0 0 0 229102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154619 0 0 0 0 0 0 89474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128784 0 0 0 0 103550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDFNVPMKDGVITNENR MGYG000001255_00368;MGYG000002272_00148;MGYG000001300_02037;MGYG000000039_00980;MGYG000000195_00272;MGYG000002223_00500;MGYG000002274_01739;MGYG000003899_01395;MGYG000000022_00457;MGYG000002641_00592;MGYG000002040_00807 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Phosphoglycerate kinase 1.0 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1229735 1393595 2575577 1856177 530301 1152534 1041475 0 1484368 1385351 0 747258 0 1771360 1173974 1483294 1585251 1513597 2212681 1851306 0 1158028 1284511 651494 1461735 1297009 1173366 563492 0 363530 0 622054 2257715 2207160 0 1168718 888446 2112040 1879741 2308513 2642496 2490091 1625230 2327701 2913506 0 1977258 625667 0 2402004 0 2769167 2624024 1392601 2710980 1291268 3073123 2966699 0 1751042 2130644 2095749 1030065 2459284 2320835 2346814 0 1902990 0 2412580 2602166 1941335 0 1964957 1845778 1846070 0 367679 522971 0 432827 0 492741 0 812854 0 0 0 0 0 0 486317 0 734041 0 332571 0 0 1413455 0 0 0 411788 1938593 0 0 0 0 0 483044 0 572890 455688 0 1363567 1167418 2366643 1301395 1542605 2122176 2690312 0 1594280 1259528 0 2366409 0 993021 1554111 1702536 1303236 974124 2510071 1584694 0 1261664 1569782 820490 2048001 1469294 1854325 1108584 0 1978116 0 1529640 2111018 1481191 0 692287 1639533 1665588 0 0 482865 0 0 0 437743 0 0 376280 0 0 0 399882 0 340060 0 1356244 0 0 0 0 1967022 0 0 345272 0 1431697 0 0 0 318292 537861 0 0 448238 0 482747 -(Pyro-carbamidomethyl)CDGADEAEALAAAIELIK MGYG000003266_00144;MGYG000002961_01622;MGYG000000188_00406;MGYG000003122_01007;MGYG000003274_01389;MGYG000000802_00030;MGYG000001636_01240;MGYG000002919_00987;MGYG000001086_00655;MGYG000004875_01407;MGYG000002065_00911 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1925@1|root,COG1925@2|Bacteria,2H0K7@201174|Actinobacteria,4CWQ1@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 PTS HPr component phosphorylation site 1.0 - 1.0 - 1.0 - 1.0 ko:K11189 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 560741 0 0 0 0 0 0 0 0 555093 1901831 0 0 0 3265350 0 0 0 0 0 0 0 0 0 0 0 0 0 1756843 0 0 0 0 0 0 0 0 0 795758 0 0 0 0 0 0 0 0 892677 0 0 0 0 1169202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546490 0 0 0 3521115 0 0 0 0 0 0 0 0 0 0 0 0 0 669858 1026947 0 0 0 0 0 0 0 0 3358796 0 0 0 0 0 0 0 0 10250478 5320202 0 0 0 8659493 0 0 0 0 0 0 0 0 0 0 0 0 0 6074156 7292930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1328598 0 0 0 2252777 0 0 0 0 0 0 0 0 0 0 0 0 0 737563 1501596 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDGDNVAPIFPK MGYG000000179_00066;MGYG000000198_00289 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG1744@1|root,COG1744@2|Bacteria,1U4NN@1239|Firmicutes,24CRY@186801|Clostridia 0.5 186801|Clostridia 1.0 S 1.0 Basic membrane protein 0.5 - 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 169880 0 0 0 0 346995 0 0 0 0 0 0 0 0 290944 0 404588 0 600105 464117 0 0 0 0 0 698257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170536 0 0 0 0 0 0 0 0 314572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138852 0 0 0 0 0 0 0 0 0 0 307893 0 0 0 0 0 0 0 0 0 0 0 205929 0 0 0 0 0 0 0 0 0 2693890 0 0 3451582 0 1063217 0 0 2667907 3943394 0 0 0 0 3189448 0 2136828 0 2444869 1854264 0 1217033 0 1183652 0 3181600 4017593 0 5528318 0 2197485 0 0 2503465 0 0 2403122 0 -(Pyro-carbamidomethyl)CDIKQEWADGGKEK MGYG000002517_00541;MGYG000000154_01283 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 114971 0 0 0 175566 0 0 0 0 0 0 0 0 0 0 213654 0 0 0 0 0 89210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1383176 0 0 2698934 0 0 0 2087673 3044311 0 0 0 0 2322485 0 1367405 2637042 0 2516718 2740547 0 0 0 0 1712894 1229350 2159033 0 0 0 0 0 0 0 2287232 0 1625194 0 117142 0 0 111760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDIKQEWAENGLAK MGYG000001300_00294;MGYG000003166_01335 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDTSSAEFQAR MGYG000000179_00909 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,21XKR@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481684 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDVAALVGK MGYG000000074_01945 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia,22VD9@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134435 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDVDDNDELTGR MGYG000000243_02652 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,2FTV5@200643|Bacteroidia,4ARCY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Belongs to the thioredoxin family 1.0 trxA 1.0 - 1.0 - 1.0 ko:K03671 1.0 ko04621,ko05418,map04621,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 Thioredoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Fluid shear stress and atherosclerosis;NOD-like receptor signaling pathway 1.0 none 1.0 0 0 588268 483496 383419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 725092 0 0 428413 0 650542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476509 467211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825558 0 0 0 0 641661 0 398253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339755 0 0 444211 0 167346 -(Pyro-carbamidomethyl)CDVDTMKTER MGYG000002438_02511 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,2FQNW@200643|Bacteroidia,22ZVG@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase family, NAD-binding Rossmann fold 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C 1.0 - 1.0 GH109 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CDVESTKANQ MGYG000002171_02571;MGYG000000243_02590 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1256@1|root,COG1256@2|Bacteria,4PKVX@976|Bacteroidetes,2G05N@200643|Bacteroidia,4AWF1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 bacterial-type flagellum assembly 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1328088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150791 0 0 0 0 939048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CEAAIAAGKFDDEIVPVPVK MGYG000002670_01511;MGYG000003694_00877;MGYG000002492_00657 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8514735 0 7331263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12955829 0 0 0 0 13014455 0 0 52572651 0 24983199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8807164 0 0 0 0 53798382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12605380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CEAAIAAGKFDDEIVPVPVKVK MGYG000002492_00657 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1190017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1208085 0 0 0 0 997363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CEDDKLDVALDVIKK MGYG000002293_01994;MGYG000003697_01048;MGYG000002834_02633 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 66701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177854 0 0 0 0 75966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 555374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341470 0 0 0 0 773914 0 0 0 0 457599 0 0 0 0 389119 0 0 0 0 431208 0 0 95852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CEEFKTEEGQKR MGYG000002528_01287 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,2682U@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 290005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319513 0 636891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1107287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2201811 0 711499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CEFDAIHLTR MGYG000002517_01855 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 'glutamate synthase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4,Fer4_20,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 374488 297545 0 500668 0 0 374665 0 462753 0 0 0 0 0 0 0 0 0 324691 0 0 0 0 616165 221390 0 0 0 0 0 0 0 0 0 186051 278308 246406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1019152 0 197409 807494 386641 216706 581128 1054091 956324 632012 0 432951 0 1195038 955398 422407 671004 0 742236 1011643 879647 0 0 0 1087239 1072600 1260534 0 0 916061 0 0 173036 752461 1261362 873234 1154052 246904 725614 346679 522718 0 354892 449496 819476 617277 784200 848332 0 593343 0 1264595 1050963 444204 897138 0 619479 609023 740706 579266 0 496941 1061853 766751 838489 0 0 669579 0 0 370046 932029 866506 997880 1053082 597619 -(Pyro-carbamidomethyl)CEGDTGSPEVQVAVLTAR MGYG000000002_01947;MGYG000000171_00631;MGYG000002298_00958;MGYG000002966_03339;MGYG000000133_01737;MGYG000000201_02701;MGYG000004733_03076;MGYG000000212_01974 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4H3DG@909932|Negativicutes 0.75 909932|Negativicutes 0.75 M 0.75 Belongs to the UDP-glucose GDP-mannose dehydrogenase family 0.75 - 0.75 - 1.0 - 1.0 ko:K02474 0.75 ko00520,map00520 0.75 - 0.75 R06894 0.75 RC00291 0.75 ko00000,ko00001,ko01000,ko01005 0.75 - 1.0 - 1.0 - 1.0 UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 0.75 none 1.0 0 0 246000 0 0 0 0 411501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339018 0 0 0 0 0 0 0 0 0 0 269646 0 523496 0 0 0 0 0 0 0 0 0 0 0 0 504667 0 0 0 304508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295956 0 0 0 0 0 0 0 0 0 761595 883221 794343 1331701 0 0 1119709 605159 0 1213306 0 663690 0 2207160 0 456877 0 0 0 0 937902 0 0 0 0 748717 0 0 1409106 0 0 885418 1547551 706956 0 963157 560596 820970 -(Pyro-carbamidomethyl)CEPNKLDELLHPVFDKK MGYG000004797_01193;MGYG000002560_01450;MGYG000002478_03849 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 1300317 0 0 0 0 0 0 0 0 0 0 1724115 0 669612 0 0 0 0 887260 0 0 0 0 1137518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1042419 0 0 0 0 0 0 0 0 0 0 1305192 0 500639 0 0 0 0 476843 0 0 0 0 495528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675986 0 0 0 0 0 0 0 0 0 0 610608 0 0 0 0 0 0 530867 0 0 0 0 596119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41697 0 0 0 0 0 0 0 0 0 0 58335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1285488 0 0 0 0 0 0 0 0 0 0 1068479 0 1049353 0 0 0 0 917363 0 0 0 0 1030596 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CETDFVAK MGYG000003645_01304;MGYG000002476_01244;MGYG000003868_00871;MGYG000002291_02397;MGYG000002205_01448;MGYG000002905_00241;MGYG000001708_01075;MGYG000000442_00899;MGYG000004769_00833;MGYG000000100_00889;MGYG000001306_01209;MGYG000002246_00674;MGYG000001783_00059;MGYG000004754_01676;MGYG000002171_01964;MGYG000003926_00749;MGYG000004797_01413;MGYG000003521_01644;MGYG000004763_01244;MGYG000002438_01052;MGYG000002120_01117;MGYG000003693_02548;MGYG000004464_00789;MGYG000002540_02892;MGYG000001552_01770;MGYG000000170_01177;MGYG000002930_00993;MGYG000000098_01947;MGYG000002935_00870;MGYG000000358_00459;MGYG000002236_01429;MGYG000000413_02556;MGYG000003259_00703;MGYG000002525_02210;MGYG000002478_01739;MGYG000001789_02687;MGYG000004105_00545;MGYG000001489_01081;MGYG000000243_02465;MGYG000000174_01105;MGYG000003857_00549;MGYG000000273_00241;MGYG000001925_02037;MGYG000003446_00288;MGYG000001503_01830 domain d__Bacteria 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 0.35555555555555557 976|Bacteroidetes 0.7333333333333333 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 0.6666666666666666 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 0.9333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 368531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CETDFVAQNADFVK MGYG000002281_00012;MGYG000003312_00467;MGYG000000013_03147;MGYG000004876_02408;MGYG000001337_04207;MGYG000004019_01939;MGYG000001661_02572;MGYG000001378_03196;MGYG000001313_02981;MGYG000003252_02162;MGYG000000105_01496;MGYG000001345_01370;MGYG000000196_04091;MGYG000003681_02139;MGYG000000236_02875;MGYG000000029_01191 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 630195 0 0 0 0 612665 1083075 528668 822875 0 2117905 0 0 0 0 745486 0 0 0 707874 0 767344 0 915427 0 498298 0 0 0 0 0 0 0 0 0 945569 719171 0 695119 0 0 0 0 970554 585011 1063718 840835 0 1429547 0 0 0 0 793608 0 0 0 736941 0 822445 0 374491 0 900877 0 0 0 0 0 0 0 0 0 730446 758450 0 1008985 0 0 0 0 976541 1008216 817491 1081971 0 709045 0 0 0 0 311964 0 0 0 501494 0 288102 0 1525755 0 951151 0 0 0 0 0 0 0 0 0 1033377 600345 0 813665 0 0 0 0 1221102 1454283 940577 934112 0 1417764 0 0 0 0 1038978 0 0 0 818385 0 1610961 0 692027 0 1453615 0 0 0 0 0 0 0 0 0 1486834 1373953 0 0 0 0 0 0 970642 578590 924156 881937 0 1661715 0 0 0 0 796912 0 0 0 1344494 0 402661 0 1047486 0 512532 0 0 0 0 0 0 0 0 0 683649 520490 0 -(Pyro-carbamidomethyl)CETLGVAC(Carbamidomethyl)EK MGYG000002312_01590;MGYG000002756_01700;MGYG000000200_00061;MGYG000000184_03367;MGYG000000142_02496;MGYG000004735_00338;MGYG000001698_00104;MGYG000002216_01774;MGYG000001338_02420;MGYG000004785_01735;MGYG000000212_01925;MGYG000000213_03796;MGYG000000216_02775 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3XZ53@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate 1.0 folD 1.0 - 1.0 1.5.1.5,3.5.4.9 1.0 ko:K01491 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R01220,R01655 1.0 RC00202,RC00578 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 THF_DHG_CYH,THF_DHG_CYH_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylenetetrahydrofolate dehydrogenase (NADP(+)). | methenyltetrahydrofolate cyclohydrolase. - - (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10- methenyltetrahydrofolate + NADPH. | (6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H(+). 1.0 1.0 1.0 1.0 Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 627914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343935 0 0 0 0 227181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513894 0 0 0 0 362992 0 0 483449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379387 0 0 0 0 252745 0 0 708429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1162202 0 0 0 0 595089 -(Pyro-carbamidomethyl)CFAFLAGHESFAAAEGAIK MGYG000000013_02686;MGYG000003420_01320;MGYG000001658_01116;MGYG000002854_01085;MGYG000003521_00824;MGYG000002455_00321;MGYG000004824_01069;MGYG000002444_01680;MGYG000000269_00015;MGYG000003570_02445;MGYG000000781_01514;MGYG000001400_01185;MGYG000004822_01055;MGYG000004561_02010;MGYG000000042_01753;MGYG000000196_00899;MGYG000004763_01967;MGYG000004493_00376;MGYG000004797_02907;MGYG000001423_03082;MGYG000000479_02090;MGYG000001925_01569;MGYG000001806_00888;MGYG000001346_01121;MGYG000000215_01600;MGYG000003535_01608;MGYG000001871_01775;MGYG000002293_01605;MGYG000000043_00846;MGYG000000273_02192;MGYG000003221_02162;MGYG000003470_00018;MGYG000003922_03053;MGYG000003693_01584;MGYG000001415_02505;MGYG000004699_02799;MGYG000002080_00203;MGYG000002275_01873;MGYG000002218_00562;MGYG000001770_01218;MGYG000001604_01691;MGYG000002834_01893;MGYG000002108_00627;MGYG000001697_00682;MGYG000002438_03055;MGYG000004464_00921;MGYG000000029_00187;MGYG000001378_03489;MGYG000000045_01847;MGYG000002281_03938;MGYG000001599_00424;MGYG000001763_00631;MGYG000002098_00644;MGYG000000707_02290;MGYG000001760_00836;MGYG000003446_01092;MGYG000004019_01333;MGYG000002478_02896 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.43103448275862066 976|Bacteroidetes 0.7586206896551724 S 1.0 Psort location Cytoplasmic, score 8.96 0.6724137931034483 - 0.9137931034482759 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 578828 0 0 0 0 0 0 0 0 0 0 0 0 14069114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733539 0 0 0 0 0 0 0 0 0 0 24833639 0 1431229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18005074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22712349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8870748 0 0 0 0 0 0 0 0 0 0 58784960 0 -(Pyro-carbamidomethyl)CFDAANAAAEEKVEAVR MGYG000002478_04136 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1669114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 345467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CFDAANAAAEEKVEAVRK MGYG000002478_04136 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 825822 0 0 0 0 806050 0 0 0 0 0 0 968629 0 0 975558 0 752937 794557 0 0 850769 839597 862393 0 875570 0 1005039 0 0 0 0 0 0 962731 0 820365 0 528214 0 0 0 0 272962 0 0 0 0 0 0 766368 0 0 931031 0 272935 525150 0 0 299744 514363 742239 0 952417 0 521086 0 0 0 0 0 0 882138 0 638319 0 331243 0 0 0 0 353213 0 0 0 0 0 0 475352 0 0 438009 0 1025110 323091 0 0 278738 440239 123805 0 253041 0 450983 0 0 0 0 0 0 449521 0 232635 0 116603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 266655 0 0 0 0 0 0 0 509171 0 0 0 0 0 0 0 0 321208 0 102887 0 518608 0 0 0 0 796190 0 0 0 0 0 0 645432 0 0 493305 0 1247333 751398 0 0 488809 964072 513452 0 527053 0 1137539 0 0 0 0 0 0 1137485 0 1103808 0 -(Pyro-carbamidomethyl)CFDADELKR MGYG000002506_01728 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,1RRBP@1236|Gammaproteobacteria,3XP14@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 glycerophosphoryl diester phosphodiesterase 1.0 glpQ 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 1.0 3.1.4.46 1.0 ko:K01126 1.0 ko00564,map00564 1.0 - 1.0 R01030,R01470 1.0 RC00017,RC00425 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECNA114_1301.ECNA114_2331,iECSF_1327.ECSF_2119 1.0 GDPD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerophosphodiester phosphodiesterase. glycerophosphoryl diester phosphodiesterase. Broad specificity for glycerophosphodiesters; glycerophosphocholine, glycerophosphoethanolamine, glycerophosphoglycerol and bis(glycerophospho)-glycerol are hydrolyzed. a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 743052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CFDIGRDHYYYDDYENER MGYG000004797_02600;MGYG000002478_03184 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,2FMRY@200643|Bacteroidia,4AMCU@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glycosyl hydrolase 57 family 1.0 amyA 1.0 - 1.0 3.2.1.1 1.0 ko:K07405 1.0 ko00500,ko01100,map00500,map01100 1.0 - 1.0 R02108,R02112,R11262 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH57 1.0 - 1.0 Glyco_hydro_57 1.0 - 1.0 GH57 1.0 GH57 1.0 GH57 1.0 alpha-amylase. glycogenase. Acts on starch, glycogen and related polysaccharides and oligosaccharides in a random manner; reducing groups are liberated in the alpha-configuration.-!-The term 'alpha' relates to the initial anomeric configuration of the free sugar group released and not to the configuration of the linkage hydrolyzed. Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units. 1.0 1.0 1.0 1.0 Metabolic pathways;Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 752268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CFEIEKK MGYG000000301_01375;MGYG000004733_03272;MGYG000000251_00123;MGYG000000213_04019;MGYG000000133_01193;MGYG000001338_00282;MGYG000000200_01241;MGYG000000142_01828;MGYG000000031_00555;MGYG000000002_01111;MGYG000004735_01013 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3XYME@572511|Blautia 0.9090909090909091 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 1.1.1.38 1.0 ko:K00027 1.0 ko00620,ko01200,ko02020,map00620,map01200,map02020 1.0 - 1.0 R00214 1.0 RC00105 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 malate dehydrogenase (oxaloacetate-decarboxylating). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Two-component system 1.0 none 1.0 0 982240 1053343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207572 0 0 0 0 162201 0 0 0 0 0 0 0 0 0 633572 0 0 0 0 296226 0 1748492 699149 744423 0 0 1004776 0 0 0 0 0 0 446836 0 0 0 1279675 0 0 0 0 613570 0 0 0 0 864204 0 0 2103126 0 793945 0 0 0 0 1055564 0 1437994 742151 610371 0 0 449054 0 0 0 0 0 0 911498 0 0 0 383728 0 0 0 0 602562 0 0 0 0 646154 0 0 463957 0 1190736 0 0 0 0 600528 0 1064164 490542 394026 0 0 801417 0 0 0 0 0 0 451529 0 0 0 186195 0 0 0 0 0 0 0 0 0 484175 0 0 825165 0 690757 0 0 0 0 788600 0 1103540 1146862 2633557 0 0 1408069 0 0 0 0 0 0 1539282 0 0 0 207783 0 0 0 0 542537 0 0 0 0 511146 0 0 1131024 0 2156990 0 0 0 0 1057170 -(Pyro-carbamidomethyl)CFGALQR MGYG000000074_01490 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0612@1|root,COG0612@2|Bacteria,4NDXM@976|Bacteroidetes,2FNQC@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Belongs to the peptidase M16 family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M16C_assoc,Peptidase_M16,Peptidase_M16_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 242491 314158 0 286494 225132 0 161445 0 0 176615 0 0 0 206917 196224 0 163053 0 239157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55183 516045 0 716579 816888 0 1078974 0 0 139333 0 0 0 91083 71311 0 56150 0 527572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392394 58846 0 520615 407991 0 428646 0 0 409156 0 0 0 300732 292527 0 46863 0 330098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169859 334882 0 276186 359084 0 203052 0 0 244016 0 0 0 118109 257564 0 189411 0 66167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453583 317214 0 447040 506001 0 353137 0 0 398837 0 0 0 654952 610325 0 399446 0 270982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CFITNGK MGYG000000076_01275;MGYG000000217_01340;MGYG000004740_00273;MGYG000000205_02133;MGYG000000164_00686;MGYG000000153_01461;MGYG000001637_02229;MGYG000000255_01556;MGYG000001315_01868;MGYG000000489_01025;MGYG000002670_01509;MGYG000002492_00659;MGYG000000080_01475;MGYG000000018_00071;MGYG000000204_00801;MGYG000001777_01058;MGYG000002278_01893;MGYG000000312_02425;MGYG000000127_04022;MGYG000001793_01807;MGYG000000280_01471;MGYG000002945_00737;MGYG000000139_01931;MGYG000000136_00900;MGYG000000271_02102;MGYG000004271_00233;MGYG000000389_02149;MGYG000004039_00586;MGYG000004762_01001;MGYG000001186_01721;MGYG000002517_00542;MGYG000001319_02235;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.45454545454545453 186801|Clostridia 1.0 C 0.7575757575757576 acyl-CoA dehydrogenase 0.5151515151515151 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 66130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191347 0 0 159529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210142 0 0 368960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388103 0 0 560046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CFIVTDSFLYK MGYG000002098_00441;MGYG000004733_00775;MGYG000000212_01362;MGYG000000287_00634;MGYG000002966_01058;MGYG000000031_00643;MGYG000000171_02770;MGYG000000142_00071;MGYG000000200_01803;MGYG000003822_00610;MGYG000001338_01157;MGYG000000216_02630;MGYG000002298_01049;MGYG000000133_00993;MGYG000000301_01128 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 0.8666666666666667 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 0.8666666666666667 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 252527 0 0 0 0 162014 0 0 0 0 115828 0 247476 172528 85626 0 0 0 0 86099 0 0 0 119389 0 0 0 0 0 158918 0 0 0 0 0 0 153423 0 426771 0 0 572054 304959 257654 228655 200960 0 0 1166597 0 265360 514776 0 0 192423 0 288162 321130 0 527404 0 269197 265709 0 251998 0 0 163693 546518 0 0 0 380333 218552 195284 0 188472 0 0 92916 337138 239062 426585 631544 0 0 513649 0 312231 395786 273004 0 174936 0 0 159606 0 164202 0 293469 234839 0 1306263 0 0 221166 441804 0 0 122998 176538 449479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187283 162154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481772 169998 0 0 189686 0 0 73117741 0 14168650 0 0 8480964 44461886 11253279 27077097 56062702 0 0 47685717 0 41642598 11505229 50355728 0 24727670 0 29685640 20454596 0 19698079 0 29051878 45790200 0 74985156 0 0 43380724 65875386 0 0 86085623 15805944 28108731 -(Pyro-carbamidomethyl)CFRDEDLR MGYG000004876_02985;MGYG000000133_00405;MGYG000004871_00028;MGYG000003376_01015;MGYG000000184_03179;MGYG000001346_00214;MGYG000000002_01263;MGYG000000013_03290;MGYG000002515_01154;MGYG000001337_02892;MGYG000000273_01761;MGYG000002293_01630;MGYG000000262_02041;MGYG000000312_01098;MGYG000000177_01950;MGYG000002298_01534;MGYG000000077_02526;MGYG000002477_02755;MGYG000004828_02136;MGYG000001306_01794;MGYG000002528_03034;MGYG000003697_02254;MGYG000000398_01746;MGYG000001338_02328;MGYG000002534_02980;MGYG000000229_00294;MGYG000000187_00052;MGYG000000212_01726;MGYG000004763_00125;MGYG000004558_00003;MGYG000000074_01068;MGYG000003022_00350;MGYG000003390_03348;MGYG000004502_00224;MGYG000002772_02118;MGYG000003352_01471;MGYG000004797_01951;MGYG000002492_02656;MGYG000002478_03690;MGYG000000412_00005;MGYG000002494_03433;MGYG000001345_03009;MGYG000000196_01400;MGYG000003273_01271;MGYG000002485_01149;MGYG000000142_01151;MGYG000004735_01033;MGYG000002960_00319;MGYG000000243_00388;MGYG000002024_00788;MGYG000002438_03185;MGYG000002992_00318;MGYG000004762_01202;MGYG000000028_01137 domain d__Bacteria 1.0 COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,2FMCA@200643|Bacteroidia,4AMA8@815|Bacteroidaceae 0.2222222222222222 186801|Clostridia 0.42592592592592593 J 1.0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) 0.5740740740740741 aspS 1.0 - 0.9074074074074074 6.1.1.12 1.0 ko:K01876 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R05577 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 0.9074074074074074 GAD,Glu-tRNAGln,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon 0.42592592592592593 - 1.0 - 1.0 - 1.0 GT83 1.0 aspartate--tRNA ligase. aspartyl-tRNA synthetase. - ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 1617364 2631191 3005218 1511846 0 2437644 0 2213254 1973109 2143168 2627676 0 3112975 0 2101164 3326849 2613025 0 0 2016543 0 2594975 0 2441242 1983922 1958486 1805159 0 2177367 2261386 2710262 2508060 2695317 0 0 1761549 1700100 2831575 2308775 2509628 2513024 2235467 0 2643237 0 2335343 2073968 2835589 2653944 0 2958732 0 2139000 2287423 2231048 0 0 1944833 0 2720503 0 2372283 2000216 2062758 1972555 0 2510692 3223782 2385036 2548552 2732710 0 0 2437930 2284476 2384982 2061944 3964268 3210361 2381162 0 2847659 0 2715216 2699606 2217080 2922285 0 3173584 0 2332013 2623405 2351639 0 0 2176369 0 2892240 0 2030250 2598640 2145821 2703843 0 2565325 2498678 2584644 3133868 2662909 0 0 2506627 2583302 2937837 2081256 2813496 2446962 1557852 0 2371715 0 2504439 2134892 2351820 2796877 0 2362878 0 2423273 2997633 2150131 0 0 1899218 0 2240995 0 1540107 2234812 2152990 2011331 0 2697165 2082859 512602 2732773 2875241 0 0 2177430 1788486 3439199 2225535 2972714 2407086 3759940 0 3455464 0 2757109 2670864 3218716 2471484 0 3930632 0 2606394 3232482 2865977 0 0 2769652 0 2552970 0 3470015 2426046 2448210 1997413 0 4057610 3078813 3358009 4207400 3469050 0 0 2595633 2299330 2967495 -(Pyro-carbamidomethyl)CFYALEQER MGYG000002438_03723;MGYG000000243_01720;MGYG000002478_03979;MGYG000004797_04027 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1155@1|root,COG1155@2|Bacteria,4NIB6@976|Bacteroidetes,2FMQ6@200643|Bacteroidia,4AM1M@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit 1.0 atpA 1.0 - 1.0 3.6.3.14,3.6.3.15 1.0 ko:K02117 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn 1.0 - 1.0 - 1.0 - 1.0 - 1.0 H(+)-transporting two-sector ATPase. | Na(+)-transporting two-sector ATPase. mitochondrial ATPase. | sodium-transporting two-sector ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. | A multisubunit ATPase transporter found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis.-!-The enzyme is similar to EC 7.1.2.2 but pumps Na(+) rather than H(+). cf. EC 7.2.2.3 and EC 7.2.2.4.-!-Formerly EC 3.6.3.15. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. | ATP + H2O + 4 Na(+)(in) = ADP + H(+) + 4 Na(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 705015 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CFYALSQGR MGYG000000074_00959 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1155@1|root,COG1155@2|Bacteria,4NIB6@976|Bacteroidetes,2FMQ6@200643|Bacteroidia,22TZV@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit 1.0 atpA 1.0 - 1.0 3.6.3.14,3.6.3.15 1.0 ko:K02117 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn 1.0 - 1.0 - 1.0 - 1.0 - 1.0 H(+)-transporting two-sector ATPase. | Na(+)-transporting two-sector ATPase. mitochondrial ATPase. | sodium-transporting two-sector ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. | A multisubunit ATPase transporter found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis.-!-The enzyme is similar to EC 7.1.2.2 but pumps Na(+) rather than H(+). cf. EC 7.2.2.3 and EC 7.2.2.4.-!-Formerly EC 3.6.3.15. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. | ATP + H2O + 4 Na(+)(in) = ADP + H(+) + 4 Na(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 130113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGALMMPHR MGYG000001065_00261;MGYG000002945_00023;MGYG000000179_02817;MGYG000002286_00299;MGYG000003012_02436;MGYG000000123_04491;MGYG000000184_01513;MGYG000004296_02221;MGYG000003684_03684;MGYG000001564_03631;MGYG000000205_02427;MGYG000002528_02347;MGYG000000356_00278;MGYG000000133_02978;MGYG000004884_01461;MGYG000000251_02472;MGYG000002247_00696;MGYG000000139_01214;MGYG000001531_02457;MGYG000000198_02838;MGYG000003074_00675;MGYG000004630_02620;MGYG000000152_04139;MGYG000000187_01105;MGYG000003425_04033;MGYG000000087_01701;MGYG000000233_01459;MGYG000002756_00452;MGYG000001619_01623;MGYG000002276_00117;MGYG000003821_02212;MGYG000001367_03878;MGYG000004691_02181;MGYG000001617_02721;MGYG000000050_00499;MGYG000000172_00225;MGYG000000217_03235;MGYG000004747_02388;MGYG000004879_01707;MGYG000000201_02958;MGYG000001689_01909;MGYG000000255_00182;MGYG000000806_01709;MGYG000002835_01149;MGYG000002212_02575;MGYG000002985_01348;MGYG000000193_02646;MGYG000000216_01771;MGYG000001602_00675;MGYG000002170_00636;MGYG000001493_00603 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,3Y029@572511|Blautia 0.45098039215686275 186801|Clostridia 1.0 S 0.8627450980392157 Psort location Cytoplasmic, score 8.87 0.45098039215686275 - 0.8627450980392157 - 1.0 - 1.0 ko:K07040 0.8627450980392157 - 0.8627450980392157 - 0.8627450980392157 - 1.0 - 1.0 ko00000 0.8627450980392157 - 1.0 - 1.0 - 1.0 DUF177 0.8627450980392157 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.8627450980392157 none 1.0 840183 560100 655839 0 0 1168097 0 872274 625837 1054683 1002503 936610 969649 925207 1051760 726772 275403 0 947852 906193 980288 1181443 0 920386 1024314 685423 771394 0 1291700 798932 217635 564657 475588 0 0 829202 699032 495486 1834799 1619807 1555153 0 0 1567327 0 1578274 1160102 1646703 1432098 1866560 1667624 1395810 1281426 1302146 1337429 0 1256536 1601137 1471834 1297778 0 1344605 1409472 1168717 1587812 0 2090073 1619090 1722690 1521635 1636364 0 0 1444611 1139986 1266581 990736 1369391 1055232 0 0 1292968 0 1042129 995453 1081378 962169 1457612 1305460 1225174 1035421 1040312 1206248 0 1098858 983793 981742 2365438 0 1114780 768978 1026760 1201833 0 1684764 1028054 1092737 1352544 1048077 0 0 1123755 1013495 958791 402736 760758 471174 0 0 353863 0 453752 422922 687736 466115 462965 782037 417025 537665 477036 638132 0 359968 429705 796415 451884 0 432436 442786 346230 432946 0 906565 533147 692960 921122 604467 0 0 444086 481036 337719 5735752 3656561 4085792 0 0 3570360 0 3994726 4129521 5520621 3159946 3595560 3145279 5667120 4430668 2867427 4682853 0 4320130 3168898 5862211 4896083 0 4875913 4550957 3917853 5814053 0 8361624 2445769 3823354 4489086 6417521 0 0 4770239 3711275 3647466 -(Pyro-carbamidomethyl)CGANKDTR MGYG000003535_01089;MGYG000001733_01436;MGYG000003425_04059;MGYG000000179_01927;MGYG000003353_02290;MGYG000001615_04787;MGYG000001164_02313;MGYG000000150_00934;MGYG000004296_01453;MGYG000001643_01060;MGYG000000184_00227;MGYG000004495_01226;MGYG000000146_00711;MGYG000000242_01153;MGYG000000258_01582;MGYG000003697_01524;MGYG000001065_01729;MGYG000000193_03368;MGYG000001315_01422;MGYG000000084_02464;MGYG000000142_01678;MGYG000001300_02311;MGYG000000201_03541;MGYG000002492_01827;MGYG000000249_00741;MGYG000000255_01277;MGYG000000233_02484;MGYG000004740_01746;MGYG000000198_03217;MGYG000002517_01999;MGYG000003694_01770;MGYG000000182_00198;MGYG000002641_01086;MGYG000002293_02312;MGYG000000489_00960;MGYG000002274_02526;MGYG000001637_01423;MGYG000000251_02509;MGYG000000154_00030;MGYG000003937_01472;MGYG000004638_00366;MGYG000001338_02508;MGYG000002721_02375 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia 0.5116279069767442 186801|Clostridia 0.813953488372093 H 0.9534883720930233 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 0.8372093023255814 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 272478 83953 276500 0 0 0 0 0 0 0 0 0 0 0 0 306314 216058 503550 0 0 0 0 431634 0 0 364517 0 462980 0 229101 0 186942 163037 0 215190 0 145838 0 256732 221858 292589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358897 0 0 0 0 257115 0 0 226051 0 462402 0 276732 377794 167039 176278 0 119482 0 153946 0 508921 810135 640231 0 0 0 0 0 0 0 0 0 0 0 0 515049 283380 161203 0 0 0 0 317103 0 0 566797 0 377349 0 451413 268055 430996 739660 0 395589 0 580006 660893 835521 1406994 1242635 0 0 0 0 0 0 0 0 0 0 0 0 992807 1201708 1185643 0 0 0 0 367405 0 0 1248395 0 1837913 0 966110 1422110 1069543 981912 0 1076928 0 891270 1259848 78716 0 189954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25626 0 0 116324 0 0 0 0 163660 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGASHGC(Carbamidomethyl)APIPEEGK MGYG000000223_01509 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,3VSKI@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 NifU-like N terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1410141 0 0 0 0 0 0 0 1277331 2661904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1488584 0 0 0 0 0 0 0 699368 1945339 0 685591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203557 0 0 0 0 0 0 0 182944 0 0 2132293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGASHGC(Carbamidomethyl)APIPEEGKWVYSR MGYG000000223_01509 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,3VSKI@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 NifU-like N terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1377293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGATYHLVYAAPK MGYG000000133_00066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3XZAB@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism 1.0 adk 1.0 - 1.0 2.7.4.3 1.0 ko:K00939 1.0 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 1.0 M00049 1.0 R00127,R01547,R11319 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS20110 1.0 ADK,ADK_lid 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adenylate kinase. myokinase. Inorganic triphosphate can also act as donor. AMP + ATP = 2 ADP. 1.0 1.0 1.0 1.0 Thiamine metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 966771 0 0 0 0 0 0 0 0 0 0 0 479492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 529197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2517452 0 0 0 0 0 0 0 0 0 0 0 2498310 0 0 0 0 3681308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGDTVC(Carbamidomethyl)VVK MGYG000000179_04898 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,269AQ@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 P 1.0 FeoA 1.0 feoA 1.0 - 1.0 - 1.0 ko:K04758 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 - 1.0 - 1.0 - 1.0 FeoA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1246885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGEDLNYAR MGYG000002477_02766;MGYG000002506_01246;MGYG000002494_03422;MGYG000002535_02468;MGYG000002534_02969;MGYG000002500_02895;MGYG000003372_02436 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,3XPGP@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Belongs to the pyruvate kinase family 1.0 pykA 1.0 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 2.7.1.40 1.0 ko:K00873 1.0 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050 1.0 R00200,R00430,R01138,R01858,R02320 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 1.0 PK,PK_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate kinase. phosphoenol transphosphorylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Microbial metabolism in diverse environments;Type II diabetes mellitus;Carbon metabolism;Central carbon metabolism in cancer;Metabolic pathways;Viral carcinogenesis;Glycolysis / Gluconeogenesis;Glucagon signaling pathway;Human papillomavirus infection;Purine metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 794184 0 0 0 0 0 0 798512 0 0 0 0 0 380544 0 0 0 0 795059 0 0 0 0 0 0 0 0 0 0 0 776052 0 0 0 0 567198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGELALLR MGYG000002494_01481 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,3XP3E@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation 1.0 metE 1.0 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.1.1.14 1.0 ko:K00549 1.0 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 1.0 M00017 1.0 R04405,R09365 1.0 RC00035,RC00113,RC01241 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 1.0 Meth_synt_1,Meth_synt_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. tetrahydropteroylglutamate-homocysteine transmethylase. Requires phosphate.-!-The enzyme from Escherichia coli also requires a reducing system.-!-Unlike EC 2.1.1.13 this enzyme does not contain cobalamin. 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Selenocompound metabolism;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234691 0 0 0 0 0 125319 0 0 0 0 0 0 203610 85528 0 248733 0 218251 181582 0 111069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGELGTVHR MGYG000002485_02237 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0441@1|root,COG0441@2|Bacteria,378FC@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92553 0 0 0 0 0 0 0 0 0 234929 0 0 0 0 0 0 0 0 1457414 0 0 1714430 0 0 0 1388385 1134327 0 0 0 0 1592886 0 0 0 0 0 1761592 0 1309506 0 0 0 0 0 0 0 970993 1565744 0 0 0 0 1226402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGELM(Oxidation)M(Oxidation)PHR MGYG000000967_00086;MGYG000004781_02148;MGYG000000389_00417;MGYG000001637_01679;MGYG000003828_01159;MGYG000000404_01424;MGYG000002517_01945;MGYG000004891_01821;MGYG000002963_01649;MGYG000004271_01619;MGYG000002131_00197;MGYG000004634_01055;MGYG000000127_02821;MGYG000000271_00778;MGYG000002145_00129;MGYG000000997_00132;MGYG000004210_01966;MGYG000004719_01295;MGYG000001303_02393;MGYG000001683_00880;MGYG000000136_01418;MGYG000002492_01354;MGYG000000245_01688;MGYG000000378_01329;MGYG000001793_00084;MGYG000002974_00298;MGYG000000989_00458;MGYG000002670_00826;MGYG000001027_01111;MGYG000004558_02523;MGYG000001186_01940;MGYG000000489_00567;MGYG000001652_01105 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia 0.45454545454545453 186801|Clostridia 1.0 S 0.7272727272727273 acr, cog1399 0.45454545454545453 - 0.7272727272727273 - 1.0 - 1.0 ko:K07040 0.7272727272727273 - 0.7272727272727273 - 0.7272727272727273 - 1.0 - 1.0 ko00000 0.7272727272727273 - 1.0 - 1.0 - 1.0 DUF177 0.7272727272727273 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.7272727272727273 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGELMMPHR MGYG000000967_00086;MGYG000004781_02148;MGYG000000389_00417;MGYG000001637_01679;MGYG000003828_01159;MGYG000000404_01424;MGYG000002517_01945;MGYG000004891_01821;MGYG000002963_01649;MGYG000004271_01619;MGYG000002131_00197;MGYG000004634_01055;MGYG000000127_02821;MGYG000000271_00778;MGYG000002145_00129;MGYG000000997_00132;MGYG000004210_01966;MGYG000004719_01295;MGYG000001303_02393;MGYG000001683_00880;MGYG000000136_01418;MGYG000002492_01354;MGYG000000245_01688;MGYG000000378_01329;MGYG000001793_00084;MGYG000002974_00298;MGYG000000989_00458;MGYG000002670_00826;MGYG000001027_01111;MGYG000004558_02523;MGYG000001186_01940;MGYG000000489_00567;MGYG000001652_01105 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia 0.45454545454545453 186801|Clostridia 1.0 S 0.7272727272727273 acr, cog1399 0.45454545454545453 - 0.7272727272727273 - 1.0 - 1.0 ko:K07040 0.7272727272727273 - 0.7272727272727273 - 0.7272727272727273 - 1.0 - 1.0 ko00000 0.7272727272727273 - 1.0 - 1.0 - 1.0 DUF177 0.7272727272727273 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.7272727272727273 none 1.0 1676552 1704581 1081218 1271995 0 1552208 0 1683851 1496021 1380665 2182834 0 0 0 0 1585799 1402088 456349 1300994 1727615 0 1672520 406726 1422792 1981900 1423374 1532705 747012 0 1677333 758880 0 1005738 1671052 1436570 1418100 1543904 1089573 1577319 3812748 1893063 2133222 0 995924 0 1497731 1367748 1521939 1553679 0 0 0 0 999252 1924179 2825267 1432982 1707781 0 715906 2415578 1525343 1271748 1318115 1575687 2554415 0 1276917 3636778 0 1671414 1554792 1628963 1721445 1190786 1380569 1226802 2015591 1784688 723812 0 551708 0 1019624 931538 858391 980766 0 0 0 0 1706624 950170 743381 1282432 1178025 0 864512 915055 272719 1495425 1193507 1242929 1122476 0 1052377 963701 0 1694191 1069023 1270148 1261305 914524 1710878 2612562 2525880 1325019 2742950 0 1082201 0 3258142 3474596 1585662 1728262 0 0 0 0 1788223 2365280 348851 2467899 2715807 0 0 0 631459 3859541 3498234 3379119 0 0 2611393 2809815 0 1550466 2330261 3138413 3423526 3724776 1377717 3552645 3548923 3432341 499464 0 3001147 0 2527429 3490681 4292404 2147940 0 0 0 0 2720427 3529146 889586 4209127 3058251 0 2686134 1170847 1949057 3937548 3346109 2879396 1393512 0 3301809 4313750 0 3607851 4567527 3319008 3155494 4199462 3919278 -(Pyro-carbamidomethyl)CGEWHVYHTVC(Carbamidomethyl)GAC(Carbamidomethyl)GYYR MGYG000000243_00707;MGYG000001378_03243;MGYG000001661_02741;MGYG000000042_00685;MGYG000000236_02794;MGYG000003367_02448;MGYG000002478_00477;MGYG000004479_01738;MGYG000004797_02847;MGYG000000013_03200;MGYG000003351_01374;MGYG000000196_04043;MGYG000004899_04076;MGYG000001780_04486;MGYG000002455_03824;MGYG000000781_00308;MGYG000000273_02620;MGYG000001337_04283;MGYG000000098_03799;MGYG000003363_02244 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,2FUZD@200643|Bacteroidia,4ARR4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL32 family 1.0 rpmF 1.0 - 1.0 - 1.0 ko:K02911 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L32p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 1097514 0 0 1014377 0 0 839615 0 0 0 1549145 0 0 1051702 1075273 0 0 0 0 980050 897649 1135208 0 0 1364675 966307 0 0 0 0 1100289 908249 1166885 1443689 0 661552 0 0 2568326 0 0 1547478 0 0 2293118 0 0 0 2216802 0 0 2767140 1908919 2304501 0 0 0 2515537 2737979 1746886 0 0 2306777 2217683 0 0 0 0 1857832 1847130 1742466 1519051 0 1677153 0 0 481999 0 0 653381 0 0 350160 0 0 0 299745 0 0 603164 387098 678541 0 0 0 314644 563663 286119 0 0 537330 772675 0 0 0 0 0 0 297822 273493 0 463071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527315 0 318648 0 0 0 0 670048 0 0 1017011 0 0 1455511 0 0 0 403019 0 0 371547 1021249 1938749 0 0 0 874408 1456132 1089190 0 0 774352 1870907 0 0 0 0 495277 1836135 1108955 1095048 0 1098376 -(Pyro-carbamidomethyl)CGGDHADSGK MGYG000002517_00256 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGGDHADSGKEIPIVATDGVR MGYG000002517_00256 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 848704 296922 509617 1601179 547515 473363 274956 1368982 985765 2123548 341008 413178 0 1161973 1868609 361996 727367 0 1603767 1354833 1492690 670380 0 248011 1695492 1246301 949101 0 0 470108 0 0 269509 876516 822885 1017111 917800 370210 0 0 264369 0 0 300428 0 0 0 311111 0 0 0 0 0 0 0 0 0 0 212259 368503 0 0 274111 0 0 0 0 0 0 0 0 0 0 0 268938 0 1387846 0 0 670386 0 0 0 794448 0 1197580 0 0 0 1024071 1145198 0 0 0 1244100 809351 0 0 0 0 1450459 1401773 1056900 0 0 0 0 0 0 357376 1666011 0 1536986 0 9564935 1108604 2668675 8165480 3873795 3058544 6478025 12727599 14923942 4484058 2949554 4325300 0 11414049 13225880 3900083 6809749 0 12417316 12731949 6060314 878335 0 610887 9802201 10260816 10261155 0 2456668 7052769 1903387 3534031 2106656 7680084 11153461 8845788 14158206 2939085 5965843 3821019 7461683 0 3759013 5450722 8787633 5895696 9794739 9801850 5521645 6854311 0 11501585 9428590 4173866 9382918 0 7803856 6149679 5930628 3849302 0 8454675 12653194 8098239 8398975 0 2391172 4241206 6059565 673088 6356192 8801199 8973210 12474999 12659142 8198273 -(Pyro-carbamidomethyl)CGIC(Carbamidomethyl)GEHGGEPSSVK MGYG000000236_00181;MGYG000001378_01176;MGYG000001489_03803;MGYG000000013_03892;MGYG000001461_02244;MGYG000000222_00273;MGYG000003374_01797;MGYG000002560_01450;MGYG000001780_04079;MGYG000002478_03849;MGYG000001313_01473;MGYG000003681_00659;MGYG000002455_03526;MGYG000000243_00277;MGYG000001789_01569;MGYG000004797_01193;MGYG000001306_00064;MGYG000001787_02320;MGYG000000098_03346;MGYG000001345_02795;MGYG000002438_03578;MGYG000002133_02142;MGYG000002933_01184;MGYG000000196_02017;MGYG000001661_00974;MGYG000000696_02522;MGYG000002549_01561;MGYG000003812_01931;MGYG000003363_02147;MGYG000001346_03147;MGYG000003542_00399;MGYG000003312_03561;MGYG000002218_01508;MGYG000000174_00191;MGYG000004763_00142 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 0.8285714285714286 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 2820306 0 0 0 3795976 0 0 0 0 0 0 0 0 0 0 4849027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2934423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3703456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGIVGAIAQR MGYG000002515_03899;MGYG000002494_02401;MGYG000002506_03399;MGYG000002534_04900 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,3XMF7@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 M 1.0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source 1.0 glmS 1.0 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 2.6.1.16 1.0 ko:K00820 1.0 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 1.0 - 1.0 R00768 1.0 RC00010,RC00163,RC02752 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 iE2348C_1286.E2348C_4039,iEC042_1314.EC042_4115,iECIAI39_1322.ECIAI39_4333,iECNA114_1301.ECNA114_3878,iECOK1_1307.ECOK1_4178,iECSF_1327.ECSF_3577,iECUMN_1333.ECUMN_4259,iEcSMS35_1347.EcSMS35_4097,iLF82_1304.LF82_0844,iNRG857_1313.NRG857_18570,iSFV_1184.SFV_3755,iSF_1195.SF3809,iSFxv_1172.SFxv_4151,iS_1188.S3959,iUMN146_1321.UM146_18835,iUTI89_1310.UTI89_C4281 1.0 GATase_6,GATase_7,SIS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamine--fructose-6-phosphate transaminase (isomerizing). L-glutamine-D-fructose-6-phosphate amidotransferase. Although the overall reaction is that of a transferase, the mechanism involves the formation of ketimine between fructose 6-phosphate and a 6-amino group from a lysine residue at the active site, which is subsequently displaced by ammonia (transamidination).-!-Formerly EC 5.3.1.19. D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Insulin resistance;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 365857 690740 0 798802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788629 0 693394 0 0 0 0 0 0 0 0 290470 0 0 0 0 397716 0 0 523204 701727 0 640820 0 0 0 0 0 0 0 0 0 0 457822 0 0 0 0 742203 0 573421 0 0 0 0 0 0 0 0 379422 0 0 0 0 381703 0 0 0 357922 0 0 0 0 0 0 0 0 0 0 0 0 156487 0 0 0 0 164806 0 189552 0 0 0 0 0 0 0 0 0 0 0 0 0 226803 0 0 509473 206335 0 436351 0 0 0 0 0 0 0 0 0 0 208976 0 0 0 0 436292 0 379362 0 0 0 0 0 0 0 0 378820 0 0 0 0 469057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGKEVEVFTSR MGYG000000133_01803;MGYG000000301_00524 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 2A2DC@1|root,30QQD@2|Bacteria,1UGEZ@1239|Firmicutes,25NVE@186801|Clostridia,3Y22X@572511|Blautia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 466400 0 0 175463 0 0 0 0 0 452843 724957 0 0 0 0 0 0 0 0 0 0 253112 0 288000 0 380299 0 0 0 0 0 0 0 0 0 0 400678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 875126 0 835927 1714595 0 1139648 0 0 0 1412992 1047461 0 1452749 0 0 0 1321040 0 0 0 0 0 0 382435 0 983391 0 0 1437829 613731 1126930 0 910468 0 0 0 1534545 838840 -(Pyro-carbamidomethyl)CGLC(Carbamidomethyl)AEKC(Carbamidomethyl)PK MGYG000000271_00487;MGYG000004271_01086 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1036@1|root,COG2878@1|root,COG1036@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transport complex, RnfABCDGE type, B subunit 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_13,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGLSEHFK MGYG000001689_04266;MGYG000003012_02006;MGYG000000806_00468;MGYG000003821_00299 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3XZ3D@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 ldh 1.0 - 1.0 1.1.1.27 1.0 ko:K00016 1.0 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 1.0 - 1.0 R00703,R01000,R03104 1.0 RC00031,RC00044 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Ldh_1_C,Ldh_1_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-lactate dehydrogenase. L-lactic dehydrogenase. Also oxidizes other (S)-2-hydroxymonocarboxylic acids.-!-NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme. (S)-lactate + NAD(+) = H(+) + NADH + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Cysteine and methionine metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Glucagon signaling pathway;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1000723 0 0 1970407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2391326 0 2716449 0 0 0 0 0 0 0 0 2008999 0 0 0 0 793524 -(Pyro-carbamidomethyl)CGMFYVNER MGYG000004719_00253;MGYG000000067_03067;MGYG000000141_02711;MGYG000001814_01311;MGYG000004735_00874;MGYG000002121_00509;MGYG000000562_00434;MGYG000000271_00181;MGYG000002563_01003;MGYG000004271_02124;MGYG000000389_00258;MGYG000002854_01839;MGYG000000164_02268;MGYG000002517_01401;MGYG000000515_00532;MGYG000004805_00611;MGYG000000187_01168;MGYG000002393_02328 domain d__Bacteria 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia 0.2777777777777778 186801|Clostridia 0.8888888888888888 J 1.0 Belongs to the universal ribosomal protein uS2 family 0.8888888888888888 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 377114 376326 311804 563758 0 458109 0 0 341979 0 0 0 0 357378 443430 316537 0 0 137758 494652 0 447243 0 250118 696325 687548 647193 0 0 647812 0 0 230865 297800 527673 512979 511542 232879 0 0 0 0 0 0 0 0 0 0 0 0 0 252796 0 0 0 0 122950 130735 0 0 0 0 0 0 0 0 0 0 0 0 0 114945 150623 0 0 0 491361 160975 137502 0 0 93125 0 0 233861 0 0 0 0 251287 446010 112832 0 0 275903 307492 0 195824 0 158806 356039 603584 118525 0 0 383291 0 0 107066 141864 410537 288865 392785 0 473137 0 151204 538085 0 143489 0 0 592078 0 0 0 0 563043 611066 182156 0 0 363045 468735 0 0 0 0 566566 494293 515011 0 0 360340 0 0 153275 342388 553295 392269 465532 0 1308332 886317 1066143 1026243 0 930771 0 0 926229 0 0 0 0 1373782 1222428 868739 0 0 938991 747106 0 813774 0 938295 1590818 1071135 1284365 0 0 790808 0 0 1186081 1151822 995470 1217169 1318612 1094289 -(Pyro-carbamidomethyl)CGMFYVNQR MGYG000000080_02857;MGYG000002528_02846 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493891 0 0 0 392301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 936323 0 164127 0 0 0 0 517825 0 0 0 0 402181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632024 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGMHYVNAR MGYG000000022_01263;MGYG000002272_01435;MGYG000001300_00246;MGYG000002223_00595;MGYG000001627_01481;MGYG000001157_00347;MGYG000002610_00266;MGYG000004866_00093;MGYG000002545_00160;MGYG000000195_01345;MGYG000003921_00807;MGYG000002274_00630;MGYG000002651_00048;MGYG000003937_00035;MGYG000002641_00104 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1431743 1643695 2070151 1755633 1379422 1822594 880298 1389936 1485497 1471179 1478710 1292552 2395221 1970054 1640913 1799117 1626558 2249705 1876059 1699295 1064687 1572661 2522830 1404628 1505932 1623960 1745705 2481763 1020565 1514096 1500170 1340534 1984464 1859853 1193259 1342724 1274078 1606461 2847604 1610610 2067901 2393094 1477773 2040511 2619177 1209435 2403258 773425 2322362 2622643 1911771 2319088 2277104 1541919 2674452 2517892 3463634 2046490 1093307 1191888 3262306 1633847 2694757 2146753 2232515 3309244 674581 2300166 1678722 1543345 2075913 2182733 1060324 1862913 1954957 1708451 816534 875531 897761 822580 1017813 1071608 974555 956341 980141 856684 1258813 1006663 1159866 888351 954397 938939 1018447 2314066 698344 647935 704791 712678 2009667 994386 838136 899441 611660 2714676 568245 1272596 1075890 805259 732795 966582 914201 796843 874915 832696 1051795 1138798 1666874 1193024 1208604 1388213 1430321 866358 1364219 1381823 1441233 2012384 1752692 1067858 1220451 1155519 1288698 1802794 1569752 1152500 1302378 1878813 1785121 1367823 1771093 1199846 1070199 1375520 682939 1421984 1724968 1166013 1347127 1374839 1056940 1129275 1042918 1794382 379761 465259 934750 567383 466737 435404 498138 693913 457359 487546 328315 1313455 646869 492611 303150 515443 409686 2322728 439691 260589 444345 565523 3274700 322090 514215 422135 477512 3237267 648780 502057 638262 588321 934588 541950 567787 402954 419294 698725 -(Pyro-carbamidomethyl)CGMYYVNER MGYG000000150_02990;MGYG000004747_01385;MGYG000000179_02939;MGYG000002279_01755;MGYG000000280_00470;MGYG000000255_00471;MGYG000003695_01035;MGYG000004087_03021;MGYG000000404_00635;MGYG000001315_00796;MGYG000001310_00255;MGYG000001615_00539;MGYG000000417_00486;MGYG000000909_00277;MGYG000003355_04406;MGYG000000251_01121;MGYG000000249_01234;MGYG000001645_00483;MGYG000000136_00722;MGYG000001186_00373;MGYG000004296_02310;MGYG000000146_01613;MGYG000001319_00659;MGYG000000217_03427;MGYG000000242_00797;MGYG000000312_01585;MGYG000002304_00361;MGYG000002492_01612 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,21Y04@1506553|Lachnoclostridium 0.39285714285714285 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 0.6785714285714286 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 759522 664625 1009501 0 753183 725779 533731 1200689 596553 763970 1007192 957536 877393 685410 1102030 656191 135851 0 664642 865880 0 798800 0 632691 1023472 809840 803746 0 811396 687778 730142 702974 783309 749313 841182 687812 711391 700335 867921 786919 1075121 0 1037429 231356 1207182 1161599 649921 1106206 1289380 909945 1350445 784255 811274 1083281 1551605 0 743526 1031098 0 536938 0 854703 1025678 868255 1094061 0 1165558 933000 970260 1097050 1265348 1060306 860968 1077682 690933 1324084 1129106 983716 2587814 0 1317269 1120494 1215993 1235487 1011804 1228190 1505493 1685771 1924625 1126491 1183927 2156757 1026573 0 1179255 1140785 0 1165083 0 1131409 1290960 1199778 1172773 0 1156007 1250589 1608136 1347316 3026691 1400020 1355320 1104520 1117618 2325129 179881 617650 527783 0 333184 290999 282958 366887 261862 419562 574658 460354 538704 291212 258217 384410 541100 0 451526 348093 0 292930 0 294017 339245 374849 324372 0 317891 416065 466439 429262 715177 263670 413997 322642 293774 703350 197952 503087 879518 0 750227 461058 543488 644741 709183 1224771 566787 701449 463902 885447 809558 652915 1029857 0 812518 822761 0 651888 0 552166 668086 1010563 1014198 0 1118780 595582 634706 494716 954950 988061 747239 848653 1009259 824670 -(Pyro-carbamidomethyl)CGNIHGANFK MGYG000000179_04478 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 299ND@1|root,2ZWQQ@2|Bacteria,1V769@1239|Firmicutes,25D2A@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 L-2-amino-thiazoline-4-carboxylic acid hydrolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ATC_hydrolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1074346 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGQFYVNER MGYG000000201_03495;MGYG000000002_01239;MGYG000000213_00523;MGYG000000050_02653;MGYG000004785_01641;MGYG000000184_03160 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 302186 817591 488125 0 867230 695372 0 498489 179196 427251 880409 555308 785279 227914 441713 0 368459 0 323717 0 0 831203 0 255116 509043 237120 200413 0 658083 0 395267 973057 405730 248806 0 252236 0 464680 181207 1162503 0 200210 153444 0 0 125720 0 0 178971 0 230000 0 0 0 0 0 0 0 0 0 0 171530 0 0 0 0 436314 0 1906777 486701 0 0 0 0 0 0 0 1315393 457185 0 0 0 0 226475 0 0 289097 406801 437939 210771 172915 0 295657 0 0 0 0 434860 0 0 371209 0 265688 0 345947 0 150298 1183290 369964 250479 0 0 0 356238 0 1079966 544534 0 663585 0 0 0 132273 303093 316185 217841 551626 0 0 0 124573 0 0 0 0 0 0 131083 0 0 171491 0 689280 0 1323808 746331 175497 0 0 0 0 563564 1476112 3053333 2295992 2093711 905742 1519142 2009076 1424212 1097365 1732180 1737341 1330953 1548875 2599001 1693288 0 1181929 0 1403426 0 0 1820691 0 1406985 1270355 1300547 1911711 0 2279713 0 2393067 3476352 4204231 1325891 0 1535323 1261707 1488351 -(Pyro-carbamidomethyl)CGTPLSSHEVAQGYK MGYG000000255_02938 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,21XHQ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) 1.0 ileS 1.0 - 1.0 6.1.1.5 1.0 ko:K01870 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03656 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 isoleucine--tRNA ligase. isoleucyl-tRNA synthetase. - ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830503 0 0 0 0 0 0 0 0 0 530277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGVEVGKDVTIQQLR MGYG000002517_01855 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 'glutamate synthase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4,Fer4_20,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 848135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1038727 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CGVEVTEKK MGYG000001306_02654;MGYG000004561_01031;MGYG000003493_00375;MGYG000002935_00902;MGYG000002455_03893;MGYG000001546_01550;MGYG000001378_05033;MGYG000003542_00717;MGYG000000243_01979;MGYG000001346_01525;MGYG000001415_02506;MGYG000000105_01994;MGYG000001562_01084;MGYG000001641_01493;MGYG000001313_00088;MGYG000000224_00483;MGYG000003542_00369;MGYG000000003_02519;MGYG000001345_04693;MGYG000001489_05036;MGYG000004757_00585;MGYG000004885_00605;MGYG000000053_00899;MGYG000000170_00064;MGYG000001630_01150;MGYG000000196_03983;MGYG000004720_01708;MGYG000002549_02931;MGYG000004536_01758;MGYG000000042_01430;MGYG000002478_00805;MGYG000003374_00512;MGYG000001789_00145;MGYG000001666_00329;MGYG000004797_04274;MGYG000000074_01764;MGYG000000054_03942;MGYG000003649_01855;MGYG000004105_01519;MGYG000000236_01798;MGYG000004763_01698;MGYG000004658_01196;MGYG000003681_02045;MGYG000000222_01122;MGYG000002438_02330 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 0.4666666666666667 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 0.9777777777777777 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 821902 0 0 0 0 1077193 0 0 0 0 0 0 0 0 0 0 861532 0 671448 0 0 817598 0 988646 0 1085761 0 0 0 469678 0 0 0 0 0 0 695087 0 1937732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1259675 0 700055 0 0 1480011 0 912088 0 1430021 0 0 0 1540932 0 0 0 0 0 0 1765687 0 911693 0 0 0 0 1002388 0 0 0 0 0 0 0 0 0 0 923448 0 1075887 0 0 580829 0 922092 0 607176 0 0 0 0 0 0 0 0 0 0 1158699 0 943353 0 0 0 0 1558593 0 0 0 0 0 0 0 0 0 0 705365 0 1067235 0 0 1510035 0 0 0 1591509 0 0 0 707547 0 0 0 0 0 0 908538 0 1316886 0 0 0 0 1612838 0 0 0 0 0 0 0 0 0 0 967863 0 1475236 0 0 887236 0 969441 0 1898458 0 0 0 1929229 0 0 0 0 0 0 1572584 0 -(Pyro-carbamidomethyl)CGYWHLWR MGYG000002560_01730;MGYG000001770_00199;MGYG000003493_02131;MGYG000002561_01024;MGYG000003202_01861;MGYG000000042_02678;MGYG000003693_00676;MGYG000000413_00744;MGYG000003363_02878;MGYG000000215_00689;MGYG000002293_01557;MGYG000003470_01719;MGYG000003362_00325;MGYG000004885_01331;MGYG000000196_04414;MGYG000001789_02092;MGYG000003446_00859;MGYG000002033_00365;MGYG000000138_01901;MGYG000001780_02881;MGYG000001346_02526;MGYG000002905_00715;MGYG000003680_00979;MGYG000003221_00209;MGYG000001666_02224;MGYG000000236_00388;MGYG000000415_01202;MGYG000001643_00941;MGYG000004757_00573;MGYG000003301_00088;MGYG000001345_00428;MGYG000004569_01724;MGYG000003185_00896;MGYG000000013_01171;MGYG000002549_02787;MGYG000000781_02114;MGYG000001306_03824;MGYG000002455_00144;MGYG000002540_01631;MGYG000002108_01088;MGYG000001337_03683;MGYG000004899_00334;MGYG000003697_00534;MGYG000004474_00367;MGYG000004495_01066;MGYG000000243_00095;MGYG000001920_00369;MGYG000004479_01116;MGYG000004464_00688;MGYG000001461_03964;MGYG000000029_01835;MGYG000004876_02170;MGYG000003681_00938;MGYG000001489_04394;MGYG000000305_00576;MGYG000001630_01448;MGYG000001313_00862;MGYG000002478_04117;MGYG000001364_01848;MGYG000001763_01292;MGYG000001835_01025;MGYG000002051_02389;MGYG000002438_04196;MGYG000004763_00186 domain d__Bacteria 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 0.5625 976|Bacteroidetes 0.96875 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 0.96875 - 1.0 - 1.0 - 1.0 GT2 0.984375 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 1202221 1451740 622208 1000809 1060532 848411 890189 924911 926802 977212 2318623 842725 1268368 1700021 940645 705260 750764 0 801536 1100313 1381722 739461 0 1415344 840020 1136440 1207920 0 0 1488902 1268780 1940302 984537 1800902 0 1781638 2407198 835701 1353224 1046549 1917171 1174569 1019402 1016731 717749 1572282 0 2395644 2529048 2283105 2464792 2649403 3958632 1251912 2117146 0 1863788 1688047 2701921 1405828 0 985569 3192395 1630984 1760143 0 0 0 992026 1446881 1550478 1423821 0 1456123 2803529 2294894 0 0 2593227 386347 2541280 1466896 2025727 1197219 2218688 0 4805454 0 0 0 1814305 475371 933027 0 1452361 582329 0 0 0 2770383 2557148 0 165890 0 0 0 74734 2289617 0 68570 0 0 911727 2633972 2240777 1417088 930348 0 0 3316790 0 2647581 2831993 0 3045776 0 9967376 0 1337852 2090486 3384548 0 0 171788 6209139 80641 0 320609 4800979 0 204185 0 0 0 2634051 64974 1646829 0 0 0 0 2528661 0 105427 0 0 0 2660964 892249 0 0 0 7303 2737 0 0 0 0 0 0 3505 0 0 7890 0 3818871 0 3299999 0 0 0 0 131061 0 0 116063 0 7048 5628362 0 -(Pyro-carbamidomethyl)CGYWHNFR MGYG000002298_00647;MGYG000001602_02095;MGYG000001617_02091;MGYG000000133_02129;MGYG000000142_01058;MGYG000002445_00390;MGYG000000212_02086;MGYG000000031_03215;MGYG000000171_02087;MGYG000000002_01844;MGYG000001367_00948;MGYG000000050_02874;MGYG000004296_00115 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3XZ4K@572511|Blautia 0.5384615384615384 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 1253217 1926274 780021 0 3008911 560806 0 0 1395620 0 0 0 1041375 0 0 0 1430820 0 0 0 2404413 1237571 1073659 0 0 0 2021720 1758368 0 0 0 1565799 1140177 0 944133 0 1550642 0 479502 460701 325946 0 335616 586700 0 0 285222 0 0 0 248537 0 0 0 1051333 0 0 0 0 686491 559961 0 0 0 1084877 741076 0 0 0 405129 533642 0 421719 0 568138 0 1194362 1183231 826608 0 1092748 639377 0 0 1089610 0 0 0 916819 0 0 0 315391 0 0 0 1759846 762624 865293 0 0 0 1049167 1017013 0 0 0 1429534 1068695 0 859748 0 1371214 0 1304114 668246 384303 0 536812 497328 0 0 697322 0 0 0 429995 0 0 0 487010 0 0 0 573172 278469 603758 0 0 0 885532 1737624 0 0 0 842560 269411 0 437541 0 935482 0 3984512 4085866 6729003 0 3161903 4462991 0 0 6188425 0 0 0 6440181 0 0 0 476022 0 0 0 3990217 1101127 3141823 0 0 0 1128226 6146923 0 0 0 6706467 4604260 0 3895681 0 4329110 -(Pyro-carbamidomethyl)CHDVNQTIIAFVNK MGYG000002517_01665 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 225779 0 0 0 0 0 0 0 0 0 0 0 0 0 427734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248174 0 0 0 0 0 0 394948 0 0 0 0 0 0 238608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498320 0 0 0 0 0 0 598116 0 0 0 0 0 0 555962 0 0 0 0 0 0 0 0 0 0 604708 0 0 0 0 0 0 0 0 0 0 594990 0 1046779 0 0 0 0 0 0 714915 0 0 0 0 0 0 1493172 0 0 0 0 0 0 0 0 0 0 1233608 0 0 0 0 0 0 0 0 0 0 1043086 0 -(Pyro-carbamidomethyl)CHEHINNVLAIPGNK MGYG000002438_03452 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,22VW2@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 hydrolase activity, acting on glycosyl bonds 1.0 nagA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,TAT_signal 1.0 3.2.1.49 1.0 GH109 1.0 GH109 1.0 GH109 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 540228 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CHLEDITR MGYG000000154_00552;MGYG000002517_01550 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the alpha-IPM synthase homocitrate synthase family 1.0 - 1.0 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 iHN637.CLJU_RS03250 1.0 HMGL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 532051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CHNPAYIHMGMK MGYG000001627_00502;MGYG000000573_01090;MGYG000000084_00490;MGYG000001300_01192;MGYG000003166_00684 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 357218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168819 0 0 0 0 106484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 837989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1030609 0 672391 0 0 0 0 990952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 68436 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CHNPSYVTK MGYG000002517_00959;MGYG000000389_00578;MGYG000004475_00979;MGYG000000154_00174;MGYG000004487_00003 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 0.6 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 185734 0 0 0 0 0 0 0 0 0 258150 0 0 0 0 0 0 0 0 0 0 596151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3033350 0 0 0 0 0 0 0 0 0 3415299 0 0 0 0 0 0 0 0 0 0 2987962 0 3289716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CHPFFTGK MGYG000002944_01662;MGYG000003241_01136;MGYG000004482_01642;MGYG000002098_01144;MGYG000000412_00435;MGYG000000258_00827;MGYG000002095_00519;MGYG000003819_01132;MGYG000002926_00350;MGYG000003116_02088;MGYG000001911_00529;MGYG000004779_01763;MGYG000000358_01112;MGYG000003494_00340;MGYG000000377_00044;MGYG000004487_01757;MGYG000004734_00288;MGYG000002287_01308;MGYG000003581_01223;MGYG000003538_00848;MGYG000002720_00511;MGYG000003589_02457;MGYG000003549_00736;MGYG000002506_03634;MGYG000001732_01677;MGYG000003621_00559;MGYG000004221_00006;MGYG000003142_02526;MGYG000002323_04044;MGYG000003428_00399;MGYG000001685_00344;MGYG000002996_01085;MGYG000003484_01382;MGYG000002794_00382;MGYG000003582_00806;MGYG000002057_00277;MGYG000002934_01800;MGYG000002515_03711;MGYG000000371_00886;MGYG000003311_01734;MGYG000000392_00573;MGYG000001502_01406;MGYG000004475_00421;MGYG000004517_00716;MGYG000004743_00460;MGYG000002156_00083;MGYG000000836_00997 domain d__Bacteria 1.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,269AE@186813|unclassified Clostridiales 0.23404255319148937 186801|Clostridia 0.6595744680851063 J 1.0 Binds the 23S rRNA 0.48936170212765956 rpmE 0.9148936170212766 - 0.8297872340425532 - 0.9148936170212766 ko:K02909 0.9148936170212766 ko03010,map03010 0.9148936170212766 M00178 0.9148936170212766 - 0.9148936170212766 - 0.9148936170212766 br01610,ko00000,ko00001,ko00002,ko03011 0.9148936170212766 - 1.0 - 1.0 - 1.0 Ribosomal_L31 0.9148936170212766 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9148936170212766 0.9148936170212766 0.9148936170212766 0.9148936170212766 Ribosome 0.9148936170212766 none 1.0 1773738 1762884 1878015 0 1586957 2626323 1992515 2185593 1666156 2177648 990780 0 1224644 2681279 1908091 1375537 2493483 1112712 1723488 1871379 1957792 3066299 1145410 129690 1848217 2171606 1746655 1125764 0 1519470 1798149 2202690 1775042 2363422 2444629 2020964 1917756 1684173 1318013 1068945 1452279 0 1035086 1496894 1141297 1676790 1505763 1682696 1292561 0 1146917 1253033 1479709 1117092 1036430 508685 1512991 1206055 1164437 1510801 526677 1290478 1018052 1291422 1343217 569278 0 1054541 739102 1124044 1305878 1330204 1742178 1387053 1369387 1404016 2013926 1856136 2639855 0 2546533 3998053 2361449 2507603 2453624 2298092 2258907 0 2548733 2462616 2181487 2299107 2033693 2175193 2234669 2273512 2117419 2681302 1658883 3055840 2534850 2321498 2330849 1613410 0 2005594 2937654 1782299 1801294 2433825 2615879 2678431 2407523 1949745 2326545 2416206 2231663 0 1871743 2700960 2606359 3055751 2340014 3466913 1972150 0 2849561 1947774 2294574 2276257 2235031 1336468 2444934 1870260 2190792 2578569 1606323 2048805 3026538 2942581 2600129 911250 0 2138839 1576492 2558610 2401561 3985765 3302087 3079070 2812478 1651693 0 340222 778507 0 0 783864 699720 925165 690221 657373 573015 0 739675 570668 644652 511966 1074840 1146916 898275 0 685383 739188 1235884 1201214 713902 683181 599013 1111303 0 597010 612946 248063 467872 1090100 1164057 582402 640175 682326 -(Pyro-carbamidomethyl)CHPFYTGK MGYG000003683_00994;MGYG000001292_00592;MGYG000001300_00389;MGYG000002105_00013;MGYG000003891_02556;MGYG000004702_00491;MGYG000002223_00333;MGYG000000708_00823;MGYG000001485_00826;MGYG000002059_00084;MGYG000002494_01915;MGYG000004565_01425;MGYG000004834_02241;MGYG000004866_01409;MGYG000003408_00608;MGYG000002139_00894;MGYG000000073_00598;MGYG000001483_02679;MGYG000002854_00783;MGYG000001627_01530;MGYG000002370_03761;MGYG000000953_01713;MGYG000001424_00163;MGYG000000427_01317;MGYG000004201_01078;MGYG000004564_00748;MGYG000002040_00344;MGYG000002485_02213;MGYG000000045_02320;MGYG000003166_00009;MGYG000001779_00921;MGYG000002651_01024;MGYG000003452_00770;MGYG000002395_00480;MGYG000002224_00322;MGYG000001279_02159;MGYG000002802_00949;MGYG000000573_00476;MGYG000003465_00870;MGYG000002274_00606;MGYG000002469_01597;MGYG000000022_01287;MGYG000004707_01413;MGYG000003921_01139;MGYG000001440_01124;MGYG000001490_00439;MGYG000001480_01524;MGYG000003387_02745;MGYG000002993_01881;MGYG000002045_01614;MGYG000001136_00960;MGYG000003450_00029;MGYG000003313_00119;MGYG000000435_01031;MGYG000000479_01462;MGYG000001157_01667;MGYG000001624_00848;MGYG000000636_01561;MGYG000000303_01723;MGYG000001448_01935;MGYG000001601_01455;MGYG000002753_00307;MGYG000001563_00283;MGYG000000989_02899 domain d__Bacteria 1.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3WKI1@541000|Ruminococcaceae 0.296875 186801|Clostridia 0.515625 J 0.953125 Binds the 23S rRNA 0.734375 rpmE 0.953125 - 0.765625 - 1.0 ko:K02909 0.953125 ko03010,map03010 0.953125 M00178 0.953125 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.953125 - 0.96875 - 1.0 - 1.0 Ribosomal_L31 0.9375 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.953125 none 1.0 1668498 1740259 2291431 2378427 1203829 1557680 1255257 1482058 1656353 1723669 1258946 1438647 0 2407677 1537666 2264174 1973925 3420559 2145107 1707448 1095866 1581666 3384382 1989593 1639855 1941710 1713624 3880104 819552 913618 1629027 1714871 2318817 2715989 1376802 1662268 1660666 1962314 6114023 5975688 7119780 5598918 4519727 7987766 6399001 4144918 7101795 6194383 5644205 6401141 0 5843037 5533088 5139248 7294093 2966774 7604763 4895073 4811489 6767678 4656445 6218745 7795342 5757986 5512651 4529855 4282091 6740824 3967072 4581861 6862741 5444113 3696700 4648337 5287226 5991344 921460 1098453 1068802 1189681 1342306 1272726 1176231 1052471 1113994 645604 1693877 1403128 0 1048600 905467 1393457 872148 3036235 789378 800715 911522 1251902 2376522 979670 1212403 1060582 991774 2896535 860076 1050324 1362136 946729 0 1196770 1033730 1223004 1098681 0 2002787 1510377 2631071 2209871 1966822 2250477 3150384 2086959 2587734 2366916 1980620 3477778 0 2087730 2441080 1766883 1837116 1912224 2746551 1935974 1906731 2380083 2345893 1646495 3566710 3041580 2141329 1591699 1309099 3122170 1925711 2204359 2080870 3997812 1552066 2871141 2496908 1938573 614087 566076 708213 659669 754847 675682 621874 927603 722652 666499 409672 1657421 0 563041 553767 639915 768533 6093430 648058 813101 628012 610551 6091477 654135 893217 756757 591261 5405407 853999 1011395 840898 656838 603849 742345 818292 671443 812626 825596 -(Pyro-carbamidomethyl)CHPFYTGQQK MGYG000001315_02623;MGYG000004697_01068;MGYG000002186_01718;MGYG000001645_02131;MGYG000002492_01343;MGYG000000404_01286;MGYG000001718_00208;MGYG000002212_01646;MGYG000001636_00951;MGYG000002145_01593;MGYG000000389_00478;MGYG000000268_00177;MGYG000003694_01383;MGYG000000133_01189;MGYG000002552_02137;MGYG000004681_01708;MGYG000000119_03195;MGYG000002670_00815;MGYG000004414_01891;MGYG000002065_00824;MGYG000000123_03448;MGYG000002278_00861;MGYG000002756_02545;MGYG000001777_00587;MGYG000001310_01807;MGYG000004317_01587;MGYG000000251_00253;MGYG000004884_02111;MGYG000003096_00337;MGYG000000204_00863;MGYG000001338_01040;MGYG000002919_00814;MGYG000000359_01733;MGYG000001193_00607;MGYG000001637_01986;MGYG000000136_00322;MGYG000002312_02603;MGYG000000187_01464;MGYG000002835_02384;MGYG000002970_00284;MGYG000000301_01379;MGYG000000693_00533;MGYG000004548_01514;MGYG000002517_01891;MGYG000000038_00186;MGYG000000356_00302;MGYG000000212_01164;MGYG000004719_00151;MGYG000002985_00203;MGYG000000171_01130;MGYG000004869_02681;MGYG000000493_00772;MGYG000002580_02047;MGYG000003122_00496;MGYG000002978_01849;MGYG000000802_01723;MGYG000001319_00822;MGYG000004296_00580;MGYG000001374_00187;MGYG000000184_01331;MGYG000004558_01746;MGYG000000489_00557;MGYG000000050_03075;MGYG000000484_00653;MGYG000004875_00363;MGYG000000213_02733;MGYG000000201_01344;MGYG000000280_02121;MGYG000000095_02446;MGYG000002961_00396;MGYG000000002_00125;MGYG000000200_00582;MGYG000004785_00522;MGYG000004055_00977;MGYG000000245_01527;MGYG000002947_00032;MGYG000003851_01403;MGYG000000154_00334;MGYG000000206_02001;MGYG000000164_02373;MGYG000002050_00612;MGYG000002775_01690;MGYG000003266_00923;MGYG000002298_01368;MGYG000001607_00699;MGYG000004842_00378;MGYG000004733_03276;MGYG000000188_00340 domain d__Bacteria 1.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZ78@572511|Blautia 0.4318181818181818 186801|Clostridia 0.7727272727272727 J 0.9659090909090909 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family 0.4318181818181818 rpmE 0.5340909090909091 - 1.0 - 0.5681818181818182 ko:K02909 0.5340909090909091 ko03010,map03010 0.5340909090909091 M00178 0.5340909090909091 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.5340909090909091 - 1.0 - 1.0 - 1.0 Ribosomal_L31 0.5340909090909091 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.5681818181818182 0.5681818181818182 0.5681818181818182 0.5681818181818182 Ribosome 0.5340909090909091 none 1.0 6291566 7255669 6956415 6589663 7310162 8971880 6051201 7162217 6041286 6684769 8745329 7636904 8808228 7738943 6663775 8803840 8596285 8404714 6626260 7062751 6881265 8481535 6927474 9486574 6399747 6083349 6802047 7413961 5331145 7609725 7042435 8889190 6645458 7064711 6327187 6602769 6275380 7212293 5280069 9758997 9619619 4726732 7276648 3412622 3791415 5866976 4547193 4611644 6894628 5613843 6625641 3568222 4436365 6349503 11761112 8949455 4466757 4835027 4206750 3608270 13273666 3914193 3807199 4351849 4826939 13757967 5356555 4524519 10625227 7915242 11584102 4784364 5498419 4278084 4120871 7912981 3465134 6469134 8415506 2825756 5716994 4494855 2827026 4033716 4502386 3805470 5855137 5029076 6269229 3578142 3589763 6293466 3448148 9608581 3959414 3841113 3057637 3883997 7728142 3550837 4366289 3473650 4397752 9588071 3622764 4020252 5786267 5775922 6250776 3533085 3207093 3878749 3839287 8648142 6285868 8416253 4568012 5975521 5778733 2844167 3467169 9374050 6869240 4904451 4231920 7825661 5005736 6697779 9090646 4204251 9132799 3064654 5339106 4982628 5474457 2072188 3245592 1908921 9449337 10028822 7900305 2845967 4749105 6385869 7253667 7126109 5042144 8939051 8290851 6778193 10017775 5029825 15860648 14076026 16084192 13642492 14172916 17754504 12958516 14475900 16900334 18325900 15315412 13576068 18725567 15873030 15901587 12335615 15551911 6917454 14978470 13674211 12126730 16590281 8736555 19303498 16543174 17356527 15467019 6400215 14096767 13762351 18816497 22825360 18791628 20555232 14248984 14009609 18635766 18333913 -(Pyro-carbamidomethyl)CHSFYTGQQK MGYG000000172_03808;MGYG000001619_02179;MGYG000002963_00683;MGYG000004359_00097;MGYG000004762_00617;MGYG000001367_03041;MGYG000000233_00887;MGYG000001564_00733;MGYG000000077_01563;MGYG000000087_02394;MGYG000001698_03557;MGYG000002216_00646;MGYG000000398_00199;MGYG000004735_01044;MGYG000002141_00907;MGYG000001688_00648;MGYG000001311_05376;MGYG000000217_00649;MGYG000000205_01476;MGYG000003074_00484;MGYG000004604_01270;MGYG000001797_02586;MGYG000002989_02263;MGYG000002170_01016;MGYG000003001_01693;MGYG000001606_00998;MGYG000000312_01595;MGYG000004781_01785;MGYG000001622_02362;MGYG000000255_02664;MGYG000004380_01297;MGYG000001247_01269;MGYG000003355_01554;MGYG000000135_03652;MGYG000000092_01672;MGYG000001714_00123;MGYG000001954_02190;MGYG000000145_02678;MGYG000001531_01419;MGYG000002445_02309;MGYG000000179_01087;MGYG000001707_01263;MGYG000001199_01801;MGYG000002974_01366 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,220Y9@1506553|Lachnoclostridium 0.5454545454545454 186801|Clostridia 1.0 J 0.8636363636363636 50S ribosomal protein L31 0.5454545454545454 rpmE 0.7727272727272727 - 1.0 - 0.9090909090909091 ko:K02909 0.7727272727272727 ko03010,map03010 0.7727272727272727 M00178 0.7727272727272727 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.7727272727272727 - 1.0 - 1.0 - 1.0 Ribosomal_L31 0.7727272727272727 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Ribosome 0.7727272727272727 none 1.0 0 0 0 0 0 2188798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2113411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1975732 0 0 0 0 0 0 0 0 3485409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2713404 0 0 0 0 0 0 0 0 0 0 0 0 2362235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1620300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7563610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2859553 0 0 -(Pyro-carbamidomethyl)CHSQAFTIK MGYG000002494_02089;MGYG000002506_03058 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,3ZJ2I@590|Salmonella 0.5 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate 1.0 asd 1.0 GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009090,GO:0009092,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0033554,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.2.1.11 1.0 ko:K00133 1.0 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00017,M00018,M00033,M00525,M00526,M00527 1.0 R02291 1.0 RC00684 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECP_1309.ECP_3527 1.0 Semialdhyde_dh,Semialdhyde_dhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate-semialdehyde dehydrogenase. L-aspartate-beta-semialdehyde dehydrogenase. - L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Monobactam biosynthesis;Cysteine and methionine metabolism;Metabolic pathways;Lysine biosynthesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 347897 0 0 0 0 0 0 0 0 0 0 0 0 0 601301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265799 0 0 0 0 224653 0 0 1574445 0 0 0 0 0 0 0 0 0 0 0 0 0 1779536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1352551 0 0 0 0 1262836 0 0 413575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228107 0 0 0 0 328698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CHVLVAMNPSALK MGYG000000196_01836;MGYG000001345_04520 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,2FN08@200643|Bacteroidia,4AM9Z@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 2-oxoacid acceptor oxidoreductase, alpha subunit 1.0 porA 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00174 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFOR_II,POR,POR_N,Transketolase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 308608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 839447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CIAEIGTYDPNLEPSAYKVDEEAAKK MGYG000000133_02937 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3Y0EA@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 - 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1500413 0 0 0 0 0 0 0 0 0 0 3292397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2305867 0 0 0 3408505 0 0 0 0 882581 -(Pyro-carbamidomethyl)CIAGSVADDRK MGYG000003521_00824;MGYG000002438_03055 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,22VUI@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 GGGtGRT protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 486650 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 768017 0 0 0 0 0 276640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302483 0 0 0 0 0 658279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CIAMGPTDGLVR MGYG000001315_02894;MGYG000000187_00876;MGYG000000028_00163;MGYG000000356_01862;MGYG000002528_01017;MGYG000000262_00505;MGYG000004317_01545;MGYG000001777_00207;MGYG000000562_01724;MGYG000004735_02328;MGYG000002492_00116;MGYG000001543_00548;MGYG000000484_00117;MGYG000002517_03146 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,25UUG@186806|Eubacteriaceae 0.42857142857142855 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 361001 0 262590 0 0 117139 0 336411 0 358580 0 112399 0 343868 88738 94011 250957 0 486533 0 0 479047 0 0 371494 256394 0 0 0 224802 0 0 106562 321194 355885 256675 139972 0 195270 0 358384 0 0 0 202432 349587 0 0 0 0 0 95036 0 0 0 0 302083 0 0 0 0 260434 145095 200017 286029 0 0 0 0 0 260083 253684 251317 270884 145471 173912 225302 0 377222 0 0 264787 180251 268216 0 0 0 369590 0 250660 220570 0 0 0 296602 0 0 395712 0 0 261178 394681 379363 0 0 142549 0 0 336722 280230 348584 0 115441 267001 860074 0 378987 0 0 397187 476723 850171 0 564253 0 663535 0 1060028 1018461 627473 648200 0 832776 0 0 0 0 0 690973 784784 1082638 0 0 819544 0 0 606927 579675 1006029 777856 967954 333885 619317 0 889449 0 0 477127 619408 588742 0 1000043 0 571089 0 868763 812280 482187 744873 0 634844 0 0 629755 0 431913 733046 638470 762411 0 0 392408 0 0 805649 801596 863539 834865 844033 769120 -(Pyro-carbamidomethyl)CIAMSSTDGLVR MGYG000001300_02368;MGYG000002040_00953;MGYG000004022_00852;MGYG000001065_01646;MGYG000003899_00596;MGYG000002545_01157;MGYG000000036_00372;MGYG000000022_01420;MGYG000001531_01376;MGYG000000195_00674;MGYG000002641_02172;MGYG000002610_02017;MGYG000002274_00866;MGYG000000133_01065;MGYG000002651_01644;MGYG000002780_01575 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3WGVH@541000|Ruminococcaceae 0.75 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 214993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CIDDVSEISAIGHR MGYG000002040_00963 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900758465|m__MGYG000002040 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407228 0 0 0 0 529257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 688462 0 0 0 0 886284 0 0 0 0 635915 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492229 0 0 0 0 597628 0 0 0 0 719101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 345672 0 0 0 0 0 0 0 0 0 325040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CIDGIVVNAEHC(Carbamidomethyl)K MGYG000001410_00317 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__Sutterella wadsworthensis_A|m__MGYG000001410 1.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2W02M@28216|Betaproteobacteria,4PQCS@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 E 1.0 Fumarase C C-terminus 1.0 aspA 1.0 - 1.0 4.3.1.1 1.0 ko:K01744 1.0 ko00250,ko01100,map00250,map01100 1.0 - 1.0 R00490 1.0 RC00316,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FumaraseC_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate ammonia-lyase. fumaric aminase. - L-aspartate = fumarate + NH4(+). 1.0 1.0 1.0 1.0 Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 307723 0 0 0 0 0 0 0 413420 0 0 0 0 0 319866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1287325 0 3529144 1369032 0 0 0 0 0 0 1445160 0 0 1895566 0 0 792266 0 1409787 0 0 0 0 0 0 0 0 0 0 2657919 0 0 0 -(Pyro-carbamidomethyl)CIDPIMTYGTEDQKQK MGYG000002517_00542 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1048699 0 0 1101212 0 0 0 0 0 0 0 0 0 820110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CIDVC(Carbamidomethyl)YHR MGYG000000262_02729;MGYG000000077_00331 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,25W5G@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 glycyl-radical enzyme activating protein family 1.0 pflC 1.0 - 1.0 1.97.1.4 1.0 ko:K04069 1.0 - 1.0 - 1.0 R04710 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4,Fer4_12,Fer4_4,Fer4_6,Fer4_9,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 [formate-C-acetyltransferase]-activating enzyme. pyruvate formate-lyase 1 activating enzyme. A single glycine residue in EC 2.3.1.54 is oxidized to the corresponding radical by transfer of H from its CH2 to AdoMet with concomitant cleavage of the latter.-!-The first stage is reduction of the AdoMet to give methionine and the 5'-deoxyadenosin-5'-yl radical, which then abstracts a hydrogen radical from the glycine residue. glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl- L-methionine = 5'-deoxyadenosine + glycin-2-yl radical-[formate C-acetyltransferase] + H(+) + L-methionine + semiquinone [flavodoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 532086 127650 0 0 636509 0 130837 0 133990 128363 0 0 0 0 0 0 0 157626 184481 0 532348 0 0 144105 0 0 0 0 0 0 307333 0 0 0 0 0 0 0 229871 0 0 0 0 620545 147130 0 0 0 0 0 0 0 0 0 0 376617 245018 0 0 0 333085 292715 0 253970 0 0 0 136829 0 0 254612 277023 0 0 0 0 1497396 327279 1437950 0 929466 239802 1160133 0 897427 371256 0 0 0 0 0 0 0 1241729 1211667 0 1162368 0 614051 1351981 0 1346564 0 0 0 252905 1004755 533614 1227268 1152034 0 0 144017 0 474898 182689 623140 0 728092 755832 322756 0 855463 308409 0 0 0 0 0 0 0 237023 644749 0 525342 0 586584 305757 0 454717 0 0 0 322447 222731 431346 0 378609 0 0 311179 0 1122073 942967 559054 0 629961 415882 585719 0 821823 931256 0 0 0 0 0 0 0 754194 671063 0 804888 0 513306 428276 0 449403 0 0 0 1560148 1254793 1538325 928729 534276 0 0 1336470 -(Pyro-carbamidomethyl)CIDYVAAHPEVR MGYG000002882_00084;MGYG000002720_00860;MGYG000002926_00665;MGYG000004525_00411;MGYG000002143_01958;MGYG000001733_00673;MGYG000004196_01674;MGYG000004487_00298 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,25UUF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 E 1.0 Lysine-2,3-aminomutase 1.0 kamA 1.0 - 1.0 5.4.3.2 1.0 ko:K01843 1.0 ko00310,map00310 1.0 - 1.0 R00461 1.0 RC00303 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,LAM_C,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine 2,3-aminomutase. - This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-It contains pyridoxal phosphate and a [4Fe-4S] cluster and binds an exchangeable S-adenosyl-L-methionine molecule.-!-Activity in vitro requires a strong reductant such as dithionite and strictly anaerobic conditions.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of S-adenosyl-L-methionine, mediated by the iron- sulfur cluster.-!-S-adenosyl-L-methionine is regenerated at the end of the reaction. L-lysine = (3S)-3,6-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 3607834 2865598 2071000 3788568 0 3313926 0 5178157 4742478 3232045 2535399 2485609 0 3333088 3900624 2294969 3283397 0 3366565 3234248 0 2671342 0 2889600 3767761 4281999 3509217 0 3767762 2106893 0 0 2209663 4024915 3739803 4484891 3679876 2097934 1192347 281644 229869 1310702 0 217137 0 1209216 1071443 915801 0 358141 0 865225 795730 0 432436 0 1276935 1052762 0 0 0 431419 744822 878347 1247781 0 1092777 750177 0 0 152646 840073 1270976 1025452 1227329 469439 3146539 2333568 2664247 3556558 0 1715456 0 3212412 2976495 3037299 1603492 2625240 0 3405234 3445752 1667155 3149762 0 5237803 2962429 0 2265369 0 1466117 3236273 3770503 3189672 0 2946099 2724077 0 0 2252902 4241383 3612849 3029050 3447450 2867561 1772101 1692903 1687357 1755619 0 1864266 0 1913896 1846935 1848644 964671 1054742 0 1705076 1640643 1481307 2155779 0 2439007 1622872 0 1254596 0 1089198 1303541 1933768 2017796 0 2724733 1710537 0 0 1349084 1663533 1823802 1786348 1444496 1582840 0 392912 0 317965 0 466650 0 0 0 0 310777 0 0 0 0 0 472983 0 719063 681671 0 0 0 0 209230 392351 657436 0 0 0 0 0 0 0 0 0 452619 0 -(Pyro-carbamidomethyl)CIEEIGTYDPTKDPSEYHVNEELAKK MGYG000002492_01364;MGYG000000154_00276;MGYG000002517_01931;MGYG000004719_01372;MGYG000000271_00791;MGYG000004271_01605;MGYG000000489_02523;MGYG000002670_00836 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 - 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 786915 0 0 1105406 0 0 0 901585 898080 0 0 0 0 0 0 0 0 0 894282 0 0 0 0 0 0 960374 0 0 0 0 0 0 0 0 573176 662963 421625 0 234943 0 0 443038 0 0 0 445965 0 0 0 0 0 0 0 0 0 0 315241 0 0 0 0 0 0 312903 0 0 0 0 0 0 0 0 0 241114 0 0 727801 0 0 469303 0 0 0 314400 496053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2127277 0 0 0 0 0 0 0 0 0 0 428992 0 1376507 0 0 1791040 0 0 0 1989547 1441416 0 0 0 0 0 0 0 0 0 1401562 0 0 0 0 0 0 1634572 0 0 0 0 0 0 0 0 1775856 1471409 1709538 0 1287576 0 0 284667 0 0 0 772276 1787884 0 0 0 0 0 0 0 0 0 1417013 0 0 0 0 0 0 1837600 0 0 0 0 0 0 0 0 1247247 1968892 2245342 0 -(Pyro-carbamidomethyl)CIEGVYHTGQR MGYG000000142_02504;MGYG000001338_02427;MGYG000004733_01559;MGYG000002298_01762;MGYG000000201_00496;MGYG000000216_02766;MGYG000004296_01205;MGYG000000133_01784 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3XZDK@572511|Blautia 0.75 186801|Clostridia 1.0 C 1.0 acetyl-CoA decarbonylase synthase complex subunit beta 0.75 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 609446 858171 0 1308138 0 0 0 0 0 0 0 0 0 0 0 0 1086878 0 0 0 0 457578 0 0 0 0 659106 0 0 0 0 492511 0 0 0 0 629154 0 215049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154269 0 0 336385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427176 0 0 0 0 359186 0 2287602 964974 0 1761144 0 0 0 0 0 0 0 0 0 0 0 0 519071 0 0 0 0 0 0 0 0 0 1245567 0 0 2109708 0 1530154 0 0 0 0 1421719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CIGGGM(Oxidation)GC(Carbamidomethyl)STIVERD MGYG000000262_02231;MGYG000000404_01795;MGYG000000204_00804;MGYG000000997_00552;MGYG000000077_02464;MGYG000000164_00683;MGYG000001814_02499;MGYG000002517_00540;MGYG000000153_01463;MGYG000000389_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.4 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.7 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CIGGGMGC(Carbamidomethyl)ATIVERD MGYG000000205_02136;MGYG000002445_02272;MGYG000000233_02446;MGYG000001617_02042;MGYG000000255_01552;MGYG000001711_01126;MGYG000001615_04304;MGYG000000281_02192;MGYG000001315_01871 domain d__Bacteria 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,4BWBU@830|Butyrivibrio 0.3333333333333333 186801|Clostridia 0.8888888888888888 I 1.0 Thiolase, C-terminal domain 0.6666666666666666 thlA 0.8888888888888888 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291111 0 0 0 0 567699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CIGGGMGC(Carbamidomethyl)STIVER MGYG000000262_02231;MGYG000000404_01795;MGYG000000204_00804;MGYG000000997_00552;MGYG000004271_00231;MGYG000000164_00683;MGYG000001814_02499;MGYG000000245_02019;MGYG000000271_02104;MGYG000002517_00540;MGYG000000389_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.5454545454545454 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.7272727272727273 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 429295 0 0 829962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368638 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CIGGGMGC(Carbamidomethyl)STIVERD MGYG000000262_02231;MGYG000000404_01795;MGYG000000204_00804;MGYG000000997_00552;MGYG000000077_02464;MGYG000000164_00683;MGYG000001814_02499;MGYG000002517_00540;MGYG000000153_01463;MGYG000000389_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.4 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.7 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 333058 0 0 551724 0 695709 283474 0 0 0 591845 0 0 0 581385 257432 402940 0 0 0 532524 541324 419953 0 0 0 0 0 0 461760 335881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2054856 1081911 832725 3331477 1931165 1535489 2004192 2920302 3957978 2156770 1251804 1632459 1392277 3555511 3433288 1447096 2854234 0 3059234 3381422 2212499 811044 0 738000 2010294 2107536 2497160 0 1168700 3259586 1218584 1325487 957633 1600516 3694096 2126224 3094152 1046809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CIHSC(Carbamidomethyl)PFGAIGSK MGYG000004271_01048;MGYG000000271_00447;MGYG000000179_00443;MGYG000001065_01137;MGYG000002234_01825;MGYG000000389_00676;MGYG000002517_01844;MGYG000002670_00991;MGYG000002492_02180 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1143@1|root,COG4624@1|root,COG1143@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Iron only hydrogenase large subunit, C-terminal domain 0.6666666666666666 - 1.0 - 1.0 1.12.7.2 1.0 ko:K00533 1.0 - 1.0 - 1.0 R00019 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe_hyd_lg_C,Fer4,Fer4_6,Fer4_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ferredoxin hydrogenase. uptake hydrogenase. Can use molecular hydrogen for the reduction of a variety of substances.-!-Formerly EC 1.12.1.1, EC 1.12.7.1, EC 1.18.3.1, EC 1.18.99.1 and EC 1.98.1.1. H2 + 2 oxidized [2Fe-2S]-[ferredoxin] = 2 H(+) + 2 reduced [2Fe-2S]- [ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 737943 0 0 0 0 0 0 0 345581 0 395920 777809 0 0 0 0 0 0 0 0 0 0 0 571176 0 0 0 0 0 0 525285 0 557182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1731788 0 0 0 0 0 0 0 785126 0 2270331 2218375 0 0 0 0 0 0 0 0 0 0 0 1939015 0 0 0 0 0 0 1266874 0 1325329 0 0 0 0 0 0 0 0 0 0 0 0 0 1326573 0 1733336 0 0 0 0 0 0 0 0 0 0 0 0 1088099 0 0 0 0 0 0 1614702 0 1683835 0 0 -(Pyro-carbamidomethyl)CIHVHATDFDR MGYG000002560_03190;MGYG000000243_01312;MGYG000002478_03183 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0438@1|root,COG0438@2|Bacteria,4NEWR@976|Bacteroidetes,2FMW0@200643|Bacteroidia,4AKN5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Glycosyltransferase, group 1 family protein 1.0 gmhA 1.0 - 1.0 2.4.1.346 1.0 ko:K13668 1.0 - 1.0 - 1.0 R11703,R11704 1.0 - 1.0 ko00000,ko01000,ko01003 1.0 - 1.0 GT4 1.0 - 1.0 Glyco_trans_4_4,Glyco_transf_4,Glyco_transf_5,Glycos_transf_1,SIS_2 1.0 - 1.0 GT4 1.0 GT4 1.0 GT4 1.0 phosphatidyl-myo-inositol dimannoside synthase. mannosyltransferase. The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs). (1) a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D- myo-inositol] + GDP-alpha-D-mannose = a 2,6-O-bis(alpha-D- mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+). (2) a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl- (1<->6)-D-myo-inositol] + GDP-alpha-D-mannose = 2-O-(alpha-D-mannosyl)-6- O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 255866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CILFNEK MGYG000001315_01111;MGYG000004733_00600;MGYG000001687_00314;MGYG000001564_01809;MGYG000000038_01493;MGYG000000077_01442;MGYG000002670_00126;MGYG000000268_00688;MGYG000001619_01501;MGYG000001476_03312;MGYG000004630_02409;MGYG000000164_01754;MGYG000002274_01022;MGYG000000404_00178;MGYG000000271_02110;MGYG000001338_01881;MGYG000002517_00259;MGYG000001493_05223;MGYG000004785_01998;MGYG000000262_02304;MGYG000000205_00108;MGYG000000252_02425;MGYG000002934_02584;MGYG000003142_01159;MGYG000000489_01562;MGYG000000301_00099;MGYG000002312_03080;MGYG000000213_01204;MGYG000000245_01078;MGYG000000145_02287;MGYG000000389_02030;MGYG000003801_01473;MGYG000000184_02616;MGYG000004558_00607;MGYG000004087_02483;MGYG000001617_02316;MGYG000001439_02537;MGYG000002279_02521;MGYG000000179_02171;MGYG000002105_01106;MGYG000001007_01036;MGYG000000087_01966;MGYG000000198_04024;MGYG000000095_02480 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 0.2727272727272727 186801|Clostridia 0.9545454545454546 F 0.5681818181818182 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 0.9772727272727273 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 157627 0 0 0 0 0 66669 175060 353991 82793 0 0 0 0 235608 37980 0 0 109096 0 450623 0 0 0 0 123671 67814 0 0 0 0 0 0 0 59310 79866 137487 0 0 0 0 0 0 0 82568 0 90139 0 0 0 0 0 266820 0 0 0 341580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86053 58138 46094 0 296340 0 0 228005 0 0 136673 177430 77928 142783 0 0 0 0 350233 0 104077 0 241485 0 144352 0 0 0 0 274319 221046 0 0 183161 0 0 0 0 0 150293 267704 0 800662 0 0 627258 0 0 483534 636357 760362 382135 0 0 0 0 621300 361479 523568 0 806830 0 481379 0 0 0 0 405289 695132 0 0 484132 0 0 0 0 526171 594019 800627 0 554273 0 0 82898 0 0 735777 439090 491463 351041 0 0 0 0 530533 246485 560292 0 430108 0 531479 0 0 0 0 198998 191664 0 0 232349 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CILFNEKGDMC(Carbamidomethyl)SVAQK MGYG000000198_04024 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 1830949 0 0 1364250 0 0 0 0 0 0 0 0 0 0 1186831 0 0 0 0 2048493 1206411 0 0 0 0 1382944 1432811 0 1503764 0 0 0 0 0 0 0 1574741 0 498501 0 0 782045 0 0 0 0 0 0 0 0 0 0 447859 0 0 0 0 417200 468012 0 0 0 0 698373 865682 0 808534 0 0 0 0 0 0 0 577352 0 1778073 0 0 2040359 0 0 0 0 0 0 0 0 0 0 1848659 0 0 0 0 1470557 1485538 0 0 0 0 1649110 2010833 0 2170756 0 0 0 0 0 0 0 1520332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682761 0 0 0 0 0 0 0 0 0 0 0 0 0 702361 0 0 0 0 506589 542122 0 0 0 0 803204 910659 0 770587 0 0 0 0 0 0 0 598803 0 -(Pyro-carbamidomethyl)CILFNEKGEMC(Carbamidomethyl)SVAQK MGYG000002934_02584;MGYG000001564_01809;MGYG000000489_01562;MGYG000002670_00126;MGYG000000268_00688;MGYG000000067_02180;MGYG000000145_02287;MGYG000001619_01501;MGYG000001476_03312;MGYG000000389_02030;MGYG000000164_01754;MGYG000002274_01022;MGYG000000404_00178;MGYG000004087_02483;MGYG000002517_00259;MGYG000001493_05223;MGYG000000179_02171;MGYG000002105_01106;MGYG000001007_01036 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 0.3684210526315789 186801|Clostridia 0.8947368421052632 C 0.47368421052631576 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 5273230 3281247 2066516 2978962 2998017 2758501 5387328 5436209 6504822 7115368 2141488 2074124 0 4646114 4340648 3221037 3744022 0 4222038 5648669 4873767 2139205 0 1166766 6558235 4158128 4265644 0 4623022 3904846 633825 0 1189263 3728655 6104154 4358862 4594597 1056723 0 351634 323769 345063 663723 201573 360246 0 418063 270058 0 0 0 562030 0 0 0 0 205505 374288 0 0 0 389681 189196 366323 413644 0 726317 492815 494398 0 400234 361901 349393 289795 124883 412005 1693139 585805 487522 1365926 269576 0 926508 1117251 1254482 2195319 294691 852270 0 1534668 1956895 821510 982089 0 1287691 1503298 1317563 660724 0 0 1061159 1209661 1896815 0 1546733 648508 0 0 833011 694183 1994449 1442908 1614998 292769 3423803 443588 866151 2353011 1132357 996961 2085502 4012957 5132669 1335001 600349 1700501 0 3635619 3467937 1151963 2053306 0 3285947 3191085 3103953 0 0 539966 4273128 5630509 4342964 0 682426 1934701 0 0 736668 3382770 4746590 3585782 5199829 539985 8369847 4213700 6235922 3566302 4270650 5180681 7946458 4512515 11047390 9325049 5483721 6898095 0 14964057 9788085 3923727 8038765 0 7644633 7554649 7562295 5966057 0 5290343 11633411 10997243 10609841 0 6899040 4861290 5915716 0 9135109 9244305 9031902 13025245 12730112 9339195 -(Pyro-carbamidomethyl)CILFNEKGEMC(Carbamidomethyl)SVAQR MGYG000001315_01111;MGYG000004733_00600;MGYG000004558_00607;MGYG000000038_01493;MGYG000002279_02521;MGYG000000245_01078;MGYG000000205_00108;MGYG000000252_02425 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,27V84@189330|Dorea 0.875 186801|Clostridia 1.0 F 0.875 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 1543149 1135544 1471654 1009220 1342312 972441 991762 2190339 1224092 1745723 1342899 1345290 0 1458164 1299427 1246516 1378670 0 1499007 1611345 1133748 888779 0 389079 1537223 1082871 1008743 0 0 0 544147 0 740408 1429261 1513121 1147414 981937 394846 1509952 1317858 633195 2092694 915987 678344 1193952 1280094 1230568 1161277 766126 724335 0 889946 1192178 335985 710009 0 1032239 1466722 1028288 451433 0 1135738 1288543 1407844 1331387 0 0 0 1422331 0 809404 1843762 1332546 1250932 1187639 683048 1681410 278206 589070 1587621 0 255505 971163 1375531 1178942 918878 666400 899024 0 1192488 1419814 1166734 1104696 0 1925067 1798476 819453 1129451 0 207812 1619487 1153250 1694713 0 0 0 374518 0 1015341 1912045 1143875 1197712 1326968 626827 480673 338303 0 513278 0 0 667471 788051 505290 523771 0 391560 0 129181 684781 0 595069 0 508825 0 675826 0 0 0 910695 570931 596044 0 0 0 382179 0 240063 449792 535512 616103 361427 0 0 393177 190834 637185 0 397511 175676 290351 279252 0 592030 109794 0 0 389940 129448 106421 0 268558 95038 202837 454818 0 377839 335383 95058 258285 0 0 0 542860 0 0 681408 0 304424 76870 511574 -(Pyro-carbamidomethyl)CILNGLGK MGYG000000013_02686;MGYG000003420_01320;MGYG000000273_02192;MGYG000003221_02162;MGYG000003470_00018;MGYG000003922_03053;MGYG000003693_01584;MGYG000002455_00321;MGYG000004824_01069;MGYG000000781_01514;MGYG000001604_01691;MGYG000004464_00921;MGYG000000042_01753;MGYG000000029_00187;MGYG000000196_00899;MGYG000001378_03489;MGYG000004763_01967;MGYG000002281_03938;MGYG000001599_00424;MGYG000004797_02907;MGYG000001925_01569;MGYG000001346_01121;MGYG000002478_02896;MGYG000004019_01333;MGYG000000043_00846 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.88 976|Bacteroidetes 1.0 S 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 342214 0 0 0 0 0 0 0 0 0 201129 243561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 430202 0 0 0 0 0 0 0 0 0 327263 495987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464169 0 0 0 0 0 0 0 0 0 289253 339249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675370 0 0 0 0 0 0 0 0 0 338130 628115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CINDVSEIDAIGHR MGYG000001300_02904;MGYG000001627_01221;MGYG000002619_01707;MGYG000003899_00603 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1527174 0 0 0 0 899836 0 377100 0 0 1155711 0 0 0 0 0 440500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519078 0 0 0 0 768141 0 699555 0 0 794432 0 0 368614 0 0 421362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724737 0 0 0 0 514851 0 339252 0 0 852830 0 0 540381 0 0 300591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1324234 0 0 0 0 1528390 0 672802 0 0 1997059 0 0 740171 0 0 551707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CIPGSVADDRK MGYG000000013_02686;MGYG000003420_01320;MGYG000004047_01253;MGYG000000347_00819;MGYG000002455_00321;MGYG000000269_00015;MGYG000000781_01514;MGYG000001400_01185;MGYG000004561_02010;MGYG000000196_00899;MGYG000004763_01967;MGYG000004797_02907;MGYG000001423_03082;MGYG000001925_01569;MGYG000001806_00888;MGYG000001346_01121;MGYG000000215_01600;MGYG000003535_01608;MGYG000001871_01775;MGYG000002293_01605;MGYG000000273_02192;MGYG000003470_00018;MGYG000003221_02162;MGYG000003922_03053;MGYG000003693_01584;MGYG000002603_00277;MGYG000001415_02505;MGYG000002080_00203;MGYG000002275_01873;MGYG000001770_01218;MGYG000001604_01691;MGYG000002834_01893;MGYG000002108_00627;MGYG000001697_00682;MGYG000004464_00921;MGYG000000029_00187;MGYG000001378_03489;MGYG000004185_01308;MGYG000000045_01847;MGYG000002281_03938;MGYG000001599_00424;MGYG000000374_01026;MGYG000000707_02290;MGYG000000345_00815;MGYG000000433_01203;MGYG000000989_03267;MGYG000003446_01092;MGYG000004019_01333;MGYG000002478_02896;MGYG000000223_01510;MGYG000001785_00655 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.45098039215686275 976|Bacteroidetes 0.7450980392156863 S 1.0 Psort location Cytoplasmic, score 8.96 0.7254901960784313 - 0.9019607843137255 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1693626 1310661 0 1387382 2745205 1617138 0 1273358 1470129 1395036 0 1640830 2495253 2049172 1821789 2451307 1655652 1604120 1574313 1685547 1705500 1260788 1748889 1672883 1464795 1763876 1780237 1453648 1435242 1649153 1814776 1886966 2329157 1552157 1751463 1820578 1480826 2307009 1303602 887683 1643022 1600138 1182468 1204309 1114048 1414434 1534304 1299369 1456281 1468887 1694221 1220173 1164444 1832982 1154325 1110848 1314072 1288139 1239125 1047320 1594234 838031 1385490 1426471 1024338 1574775 1186753 1590973 737674 1046457 1282990 1126605 1750559 1060799 1431544 1050733 1134654 419239 1390602 816279 1533030 953971 1183578 860875 1308059 945915 1387276 405397 1491489 970790 920427 1012138 944774 1676666 950617 818184 1101546 566832 1216245 882984 1025317 629203 895827 1392563 1140722 1217578 1048241 695406 952665 553087 1051294 1347227 968469 998524 1989421 2989097 4924032 2204143 3679200 4601065 2783315 2424920 2345841 2981102 5479072 2846559 3386450 1991051 2268987 4199869 2508955 6584922 2740328 1853776 1860003 5322952 5401127 4813023 2955592 2671331 2383162 8157336 3263573 2026431 3459029 3890942 4390784 2290129 2806758 2604827 2597456 4883306 788136 421176 175630 364368 1150952 0 835479 1165974 789186 360539 360300 653061 808869 388340 611996 1144138 506427 2860099 850682 1112956 593950 215158 2188391 287592 774875 760008 0 2043272 456386 1264679 404131 471273 193719 1109197 404475 430300 852311 237862 -(Pyro-carbamidomethyl)CIPGSVADHR MGYG000003425_04615;MGYG000002517_01686;MGYG000002492_01963 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 0.6666666666666666 183925|Methanobacteria 0.6666666666666666 F 0.6666666666666666 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 0.6666666666666666 purD 0.6666666666666666 - 1.0 6.3.4.13 0.6666666666666666 ko:K01945 0.6666666666666666 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 0.6666666666666666 M00048 0.6666666666666666 R04144 0.6666666666666666 RC00090,RC00166 0.6666666666666666 ko00000,ko00001,ko00002,ko01000 0.6666666666666666 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 0.6666666666666666 none 1.0 0 0 256622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610696 0 0 0 0 492940 0 0 301603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596557 0 0 0 0 530060 0 0 1088563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 868916 0 0 0 0 1210098 0 0 812182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332905 0 0 0 0 670408 0 0 497086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CIPVHGTNQSK MGYG000002293_02708;MGYG000003697_02283;MGYG000000272_01790 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 184968 0 0 0 0 0 0 220414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287930 0 0 0 0 167280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4377582 0 0 0 0 0 0 1781584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4008618 0 0 0 0 4180823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250759 -(Pyro-carbamidomethyl)CISC(Carbamidomethyl)GIC(Carbamidomethyl)ATK MGYG000002485_02284 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG1142@1|root,COG2878@1|root,COG1142@2|Bacteria,COG2878@2|Bacteria,378T9@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Putative Fe-S cluster 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 841578 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKDAGVVMTGAGATYPYGKDPHDSNIR MGYG000000255_01546;MGYG000000205_02142 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,21Z64@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 EK 1.0 COG COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Aminotran_MocR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 1763106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1752094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 906522 0 0 0 0 0 0 0 0 0 0 0 748258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 977949 0 0 0 0 0 0 0 0 0 0 0 486401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 765160 0 0 0 0 -(Pyro-carbamidomethyl)CKDFVGR MGYG000000254_00985 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Marinifilaceae|g__Odoribacter|s__Odoribacter splanchnicus|m__MGYG000000254 1.0 COG3746@1|root,COG3746@2|Bacteria,4NIID@976|Bacteroidetes,2FN19@200643|Bacteroidia,22Z0H@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Phosphate-selective porin O and P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Porin_4,Porin_O_P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1120006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 694192 0 0 0 0 -(Pyro-carbamidomethyl)CKEALGYIAEAR MGYG000002478_03489 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,2FNWD@200643|Bacteroidia,4AMHW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 KDPG and KHG aldolase 1.0 eda 1.0 - 1.0 4.1.2.14,4.1.3.42 1.0 ko:K01625 1.0 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 1.0 M00008,M00061,M00308,M00631 1.0 R00470,R05605 1.0 RC00307,RC00308,RC00435 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-dehydro-3-deoxy-phosphogluconate aldolase. | (4S)-4-hydroxy-2-oxoglutarate aldolase. phospho-2-keto-3-deoxygluconate aldolase. | hydroxyketoglutaric aldolase. The enzyme shows no activity with 2-dehydro-3-deoxy-6-phosphate-D- galactonate (cf. EC 4.1.2.55).-!-Also acts on 2-oxobutanoate. | The enzyme from the bacterium Escherichia coli is specific for the (S) enantiomer.-!-That enzyme is trifunctional, and also catalyzes the reactions of EC 4.1.1.3 and EC 4.1.2.14. cf. EC 4.1.3.16. 2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate. | (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKEALQDR MGYG000001300_02377;MGYG000002040_00944;MGYG000002641_02163;MGYG000003899_00586 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3WGRA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Synthesizes alpha-1,4-glucan chains using ADP-glucose 1.0 glgA 1.0 - 1.0 2.4.1.21 1.0 ko:K00703 1.0 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 1.0 M00565 1.0 R02421 1.0 RC00005 1.0 ko00000,ko00001,ko00002,ko01000,ko01003 1.0 - 1.0 GT5 1.0 - 1.0 Glyco_transf_5,Glycos_transf_1,HC2 1.0 2.4.1.21 0.75 GT5 1.0 GT5 0.75 GT5 1.0 starch synthase. starch (bacterial glycogen) synthase. The description (accepted name) varies according to the source of the enzyme and the nature of its synthetic product, e.g. starch synthase, bacterial glycogen synthase.-!-A similar enzyme utilizes UDP-alpha-D-glucose (cf. EC 2.4.1.11). [(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-alpha-D- glucosyl](n+1) + ADP + H(+). 1.0 1.0 1.0 1.0 Metabolic pathways;Biosynthesis of secondary metabolites;Biofilm formation - Escherichia coli;Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641796 576718 1178831 0 0 0 0 1144897 0 0 0 0 1129001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797621 0 897226 0 0 442276 0 0 762885 351640 809041 518976 966035 0 0 0 833682 0 0 0 0 1039817 0 0 0 0 0 679921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 500580 0 0 0 0 505415 0 0 0 0 545205 0 0 0 0 0 269716 0 0 0 0 0 0 0 0 0 0 1244405 0 1082228 0 0 1160495 0 0 899576 1053988 1193405 1061498 1417115 0 0 0 803943 0 0 0 0 1103502 0 0 0 0 0 1278595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232214 0 0 0 0 137163 0 0 0 0 301871 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKEDIAETAR MGYG000000205_03218;MGYG000000233_00909 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 29UEJ@1|root,30FRA@2|Bacteria,1UEGZ@1239|Firmicutes,25JDX@186801|Clostridia,2228T@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 259517 0 0 223653 0 0 0 521429 0 412519 0 0 0 414769 0 0 296462 0 0 591768 0 0 0 0 0 227749 0 0 0 0 0 0 0 473828 0 0 366757 0 1181543 0 0 1453991 0 0 0 1121400 0 1278853 0 0 0 1258815 0 0 933759 0 1023446 920717 0 0 0 0 0 948554 0 0 0 0 0 0 0 1515456 0 0 1006661 0 0 0 0 0 0 0 0 565393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401654 0 0 0 0 0 0 0 0 0 0 460168 0 297764 0 0 131217 0 0 0 0 0 718656 0 0 0 0 0 0 274525 0 480575 0 0 0 0 0 0 550317 0 0 0 0 0 0 0 498587 0 0 0 0 0 0 0 253031 0 0 0 374333 0 320899 0 0 0 263173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282090 0 0 0 0 -(Pyro-carbamidomethyl)CKEFTTPEGR MGYG000000236_01485;MGYG000004797_01485;MGYG000000243_02209;MGYG000002171_02378;MGYG000002560_02265;MGYG000002478_02033;MGYG000001346_00878 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,2FMPI@200643|Bacteroidia,4AP54@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1960820 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858576 906173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 738350 659097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427573 868935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKEFVTAEGQQK MGYG000002492_00955 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 238730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563658 0 0 2054323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2379470 0 0 0 0 2016614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKEQGVNVR MGYG000000090_02531;MGYG000002116_00410 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes 0.5 1239|Firmicutes 0.5 H 1.0 Belongs to the formate--tetrahydrofolate ligase family 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 880210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 566734 0 0 0 0 666224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124973 -(Pyro-carbamidomethyl)CKEVELGTMNLDHIR MGYG000000142_01106 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WHXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 FAD binding domain 1.0 - 1.0 - 1.0 1.3.5.1,1.3.5.4,1.3.99.33 1.0 ko:K00239,ko:K00244,ko:K17363 1.0 ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 1.0 M00009,M00011,M00149,M00150,M00173,M00374,M00376 1.0 R02164,R10330 1.0 RC00045,RC00669 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,FMN_bind,FMN_red 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. | urocanate reductase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. | The enzyme functions as part of an anaerobic electron transfer chain that utilizes urocanate as the terminal electron acceptor.-!-The activity has been demonstrated with the artificial donor reduced methyl viologen. a quinone + succinate = a quinol + fumarate. | A + dihydrourocanate = AH2 + urocanate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Histidine metabolism;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 745072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKIEQAPGQHGAR MGYG000000235_04517;MGYG000002515_03179;MGYG000002323_00410;MGYG000002494_02445;MGYG000002507_04205;MGYG000002477_00163;MGYG000002506_02937;MGYG000002534_00416;MGYG000002535_00001;MGYG000002366_00460;MGYG000000093_01116 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,3XNVS@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1078475 794758 970944 160621 904456 1380366 1014778 1306490 847287 1395303 0 800641 540162 1171484 877240 559827 770537 0 122416 1297750 0 1783662 0 1767553 1011259 906794 0 0 1125956 1091648 585375 0 931881 1187471 1114184 784575 916052 768164 0 3064737 3336483 2994317 3081939 5983419 3146674 2507108 2951309 5128383 0 2549664 1779392 3434993 2909348 2310992 3170847 0 3749628 2395998 0 6145172 0 4374790 4052018 2764357 0 0 3785987 3759115 1569489 0 3630790 2894686 2937550 2506872 2126808 2958249 1316813 1209527 1402333 327101 1048680 1793619 1196712 1269409 1130283 1671822 0 833349 1128994 990617 993790 1066647 834300 0 1049529 1262131 0 1678327 0 1623330 848427 1324839 0 0 1023032 1139911 910430 0 1074805 1466580 1214552 1097600 1074757 1007432 1937966 1446501 1642762 1676386 1200924 2125971 1949159 2492349 1812852 2143794 0 1584868 1722808 1968213 1764768 1491299 284881 0 1898044 1440599 0 2324496 0 1415228 2498202 1971028 0 0 1653749 1863621 884654 0 1732143 2936026 2745911 2138615 1228820 996243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41741 0 0 0 0 0 233100 0 0 0 -(Pyro-carbamidomethyl)CKIEQVC(Carbamidomethyl)PMK MGYG000004735_02134 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG2221@1|root,COG2221@2|Bacteria,1UI1A@1239|Firmicutes,25EAA@186801|Clostridia,27UCZ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Nitrite/Sulfite reductase ferredoxin-like half domain 1.0 dsvA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 C_GCAxxG_C_C,Fer4,Fer4_10,NIR_SIR,NIR_SIR_ferr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2048585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKLEQAPGQHGAR MGYG000002515_03179;MGYG000002494_02445;MGYG000001465_00016;MGYG000002477_00163;MGYG000002534_00416 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,3XNVS@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3219106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2281931 0 0 0 0 0 0 0 0 0 0 0 602644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKNDEETIR MGYG000002549_01439 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,2FN44@200643|Bacteroidia,4AKAD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway 1.0 nqrF 1.0 - 1.0 1.6.5.8 1.0 ko:K00351 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_6,Fer2,NAD_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 798537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1159985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 681907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKNEEETIR MGYG000001306_00763 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,2FN44@200643|Bacteroidia,4AKAD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway 1.0 nqrF 1.0 - 1.0 1.6.5.8 1.0 ko:K00351 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_6,Fer2,NAD_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 577426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545011 0 0 0 0 602435 0 0 0 0 302044 0 0 0 0 432333 0 0 0 0 731757 0 0 895813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1902944 0 0 0 0 8517890 0 0 0 0 9061562 0 0 0 0 244420 0 0 0 0 342106 0 0 314366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244130 0 0 0 0 0 0 0 0 0 326015 0 0 449752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139801 0 0 0 0 0 0 0 0 0 202822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055390 0 0 0 0 494469 0 0 0 0 310648 0 0 0 0 171349 0 0 0 0 327768 -(Pyro-carbamidomethyl)CKNTEETIR MGYG000002478_03723;MGYG000000243_00371 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,2FN44@200643|Bacteroidia,4AKAD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway 1.0 nqrF 1.0 - 1.0 1.6.5.8 1.0 ko:K00351 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_6,Fer2,NAD_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 1030557 1000701 2379723 848954 1945112 0 0 0 897517 0 0 0 2090320 1031371 0 2021518 0 1058982 0 0 0 0 1245270 0 0 903713 0 735391 0 0 0 0 2032410 0 1043620 0 1246846 1972547 511268 284568 413842 442069 939813 0 0 0 415019 0 0 0 1326361 373385 0 913887 0 105762 0 0 0 0 369767 0 0 603318 0 165446 0 0 0 0 422433 0 532615 0 378284 418896 358162 380350 692712 448917 756307 0 0 0 428210 0 0 0 1014084 437037 0 722031 0 509797 0 0 0 0 152476 0 0 433333 0 767791 0 0 0 0 344833 0 758831 0 522494 670152 0 0 0 0 0 0 0 0 0 0 0 0 0 991490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 652682 0 0 0 0 0 352858 341801 290761 483349 613845 0 0 0 432721 0 0 0 1887630 77603 0 1020996 0 852157 0 0 0 0 570032 0 0 764706 0 452606 0 0 0 0 271684 0 521694 0 673031 427004 -(Pyro-carbamidomethyl)CKPGQIKPH MGYG000002470_01245;MGYG000000196_03974;MGYG000000236_01807;MGYG000000054_03933;MGYG000001661_02666;MGYG000003681_02037;MGYG000001346_01533;MGYG000000098_02017;MGYG000001313_00097;MGYG000000013_02251;MGYG000001780_03476;MGYG000002281_02290 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.8333333333333334 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 5865546 0 4065926 0 0 4680571 0 0 5272492 0 8623603 0 0 0 5736126 0 3737109 2161985 0 4525546 0 4383708 2612079 5363390 5597794 6170300 0 2172186 0 6816958 0 0 3402509 0 5630430 4467640 5150420 3203321 569588 0 829909 0 442983 530148 0 0 1247449 624754 600851 0 0 0 1005486 0 557245 183946 0 1323988 0 176767 236953 149393 579703 1374633 0 93776 0 683156 0 0 381470 0 1107615 354453 1174558 344215 6999887 0 10029534 0 9055824 7110275 0 0 0 7637081 12862229 0 0 0 6743270 0 5852615 5969227 0 6382948 0 4140571 5096764 7513673 8663874 8725657 0 4568447 0 6629647 0 0 5111278 0 6518944 8815296 8252593 6324314 9521282 0 10640708 0 12015385 8301556 0 0 9192381 13223216 15876202 0 0 0 10229724 0 7807636 5669476 0 7258770 0 7636444 5183178 8524379 9970339 9614019 0 7606561 0 10608346 0 0 10863024 0 10952220 11496582 9628421 9891269 382527 0 307867 0 413136 611420 0 0 1000595 1014936 468715 0 0 0 175557 0 266940 375610 0 315860 0 357573 339950 477463 590009 587914 0 274858 0 942446 0 0 292287 0 309321 434896 510286 333060 -(Pyro-carbamidomethyl)CKPGQIKPHSK MGYG000000236_01807;MGYG000000054_03933;MGYG000001661_02666;MGYG000001346_01533;MGYG000003681_02037;MGYG000001313_00097;MGYG000000098_02017;MGYG000000013_02251;MGYG000001780_03476 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.7777777777777778 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 154898 437682 73361 226351 410881 0 303946 0 600273 411281 0 0 0 375794 0 0 0 0 0 500311 40768 194090 0 0 0 0 0 529691 346663 65809 207325 0 286511 0 0 159320 0 0 966808 1353403 670233 974577 771253 0 993719 0 2027885 1210273 0 0 0 385500 0 88333 0 0 0 447187 172492 300032 0 0 0 172194 0 860697 235758 1366999 773524 0 938114 0 0 200592 0 0 2221372 1111260 2128256 1615848 877226 0 1145009 0 2690969 1225426 0 0 0 1412310 0 1148884 0 0 0 1422846 994258 1976791 0 0 0 1236504 0 1130040 1327536 989193 1145677 0 804953 0 0 1659443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121956 83709 0 0 0 0 264235 84424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKPGSVTC(Carbamidomethyl)HHK MGYG000002279_01932;MGYG000001315_01207 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 2136216 0 0 1146857 0 0 0 1413243 1812145 1542452 1399785 879212 0 1677092 0 0 1876053 0 0 1160979 0 437613 1686635 0 0 0 0 0 0 0 941129 0 1357270 0 0 1212553 0 0 220683 0 0 142098 0 0 0 206957 0 205285 37831 228546 0 0 0 0 647751 0 0 0 0 136022 234135 0 0 0 0 0 0 0 54344 0 223180 0 0 0 0 0 1182099 0 0 524923 0 0 0 1162131 663850 998951 1376744 1176021 0 1286292 0 0 1105165 0 0 863601 0 406862 1686222 0 0 0 0 0 0 0 1575805 0 371720 0 0 1171273 0 0 739550 0 0 154101 0 0 0 260248 311403 938282 142254 0 0 432575 0 0 327451 0 0 378688 0 111119 468778 0 0 0 0 0 0 0 616348 0 220734 0 0 756108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKPGSVTPHTK MGYG000000802_00776;MGYG000003096_01037;MGYG000004746_00230;MGYG000003274_01474;MGYG000003851_00676;MGYG000000333_00136;MGYG000003266_00392 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CUFV@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 2775611 786575 0 0 668175 0 0 0 910294 1665107 0 1994972 0 0 2139757 0 0 0 559853 0 983507 0 460952 0 0 0 0 1043626 0 686386 0 523916 0 0 0 0 586574 0 0 0 0 0 0 0 0 0 0 84652 0 0 0 0 0 0 0 0 90443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 537047 501954 0 0 386925 0 0 0 991701 546226 0 1507542 0 0 1577733 0 0 0 1189516 0 694315 0 496755 0 0 0 0 871909 0 391526 0 861095 0 0 0 0 381473 0 1211326 1258039 0 0 943593 0 0 0 1660519 3504680 0 3179253 0 0 4009567 0 0 0 1310393 0 1712833 0 1491715 0 0 0 0 2301874 0 2272200 0 1185969 0 0 0 0 1204091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKQDSATGLYYFDTAK MGYG000000258_01692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Ruminococcus_E|s__Ruminococcus_E bromii_B|m__MGYG000000258 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 757693 465125 0 0 0 0 700113 0 0 0 445869 0 0 0 0 0 0 0 586358 0 0 0 0 0 726674 0 0 0 0 737649 0 412612 0 0 0 491164 571865 497683 357940 514470 0 0 554705 0 338648 0 0 0 496023 0 0 576602 0 0 0 0 511104 0 461564 0 0 0 376290 442174 0 0 342120 0 0 0 511561 0 0 457377 0 1161167 868238 1103102 0 0 1161071 0 1164364 0 0 0 1233576 0 0 1185577 1219523 0 0 0 875956 0 713668 0 878289 0 1501173 1094527 0 0 1415411 1136316 0 1094431 1434635 0 0 1591122 1296724 1226394 777152 1489252 0 0 1094650 0 1096569 0 0 0 956667 0 0 1216710 1326664 0 0 0 1268805 0 1413054 0 743995 0 1267503 969706 0 0 821315 1574338 0 1047575 1502979 0 0 845033 995426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKTDYEIAWTR MGYG000002528_01048 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,24BF2@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Amidase, hydantoinase carbamoylase family 1.0 - 1.0 - 1.0 3.5.1.6,3.5.1.87 1.0 ko:K06016 1.0 ko00240,ko01100,map00240,map01100 1.0 M00046 1.0 R00905,R04666 1.0 RC00096 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 beta-ureidopropionase. | N-carbamoyl-L-amino-acid hydrolase. N-carbamoyl-L-amino acid amidohydrolase. The animal enzyme also acts on beta-ureidoisobutyrate. | This enzyme, along with EC 3.5.1.77, EC 5.1.99.5 and EC 3.5.2.2, forms part of the reaction cascade known as the 'hydantoinase process', which allows the total conversion of D,L-5-monosubstituted hydantoins into optically pure D- or L-amino acids.-!-The enzyme from Alcaligenes xylosoxidans has broad specificity for carbamoyl-L-amino acids, although it is inactive on the carbamoyl derivatives of glutamate, aspartate, arginine, tyrosine or tryptophan.-!-The enzyme from Sinorhizobium meliloti requires a divalent cation for activity and can hydrolyze N-carbamoyl-L-tryptophan as well as N-carbamoyl L-amino acids with aliphatic substituents.-!-The enzyme is inactive on derivatives of D-amino acids.-!-In addition to N-carbamoyl L-amino acids, the enzyme can also hydrolyze formyl and acetyl derivatives to varying degrees. 3-(carbamoylamino)propanoate + 2 H(+) + H2O = beta-alanine + CO2 + NH4(+). | an N-carbamoyl-L-alpha-amino acid + 2 H(+) + H2O = an L-alpha-amino acid + CO2 + NH4(+). 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 304067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 836880 0 531033 381341 0 193331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423686 0 375578 0 0 0 0 410039 0 1073190 301244 0 384659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 357138 0 711534 0 0 0 0 304684 0 1337524 411499 0 881619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1417462 0 1182916 0 0 0 0 867617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKTLDEVK MGYG000000013_03147;MGYG000000243_02465;MGYG000001783_00059;MGYG000000196_04091;MGYG000004876_02408;MGYG000003521_01644;MGYG000004763_01244 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 0.8571428571428571 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKTLEEVK MGYG000004797_01413;MGYG000002549_00046;MGYG000002478_01739 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1185196 0 1484791 0 2711865 0 0 0 1425392 1784094 2430827 0 4113585 0 0 0 0 0 0 1853495 0 0 0 0 0 1656199 1747238 0 0 1537009 0 0 1825885 0 0 0 2015308 2100002 946496 0 1224904 0 1943876 0 0 0 1077741 1284110 1640730 0 3194884 0 0 0 0 0 0 792356 0 0 0 0 0 1114403 1152799 0 0 877341 0 0 1167701 0 0 0 1128220 1136660 819413 0 1417037 0 2255888 0 0 0 1151197 1315501 1404214 0 3321861 0 0 0 0 0 0 0 0 0 0 0 0 711582 1089624 0 0 0 0 0 847073 0 0 0 0 1172479 1002374 0 497549 0 431343 0 0 0 740873 933847 501562 0 1080812 0 0 0 0 0 0 252199 0 0 0 0 0 955923 465508 0 0 257128 0 0 0 0 0 0 567558 0 431338 0 1236900 0 3367296 0 0 0 1883745 1176178 1801791 0 4197917 0 0 0 0 0 0 1270339 0 0 0 0 0 2718641 0 0 0 2055793 0 0 1211870 0 0 0 2108020 1787325 -(Pyro-carbamidomethyl)CKVGDEVQLL MGYG000001770_01653;MGYG000002293_00521;MGYG000003697_01485 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0050@1|root,COG0050@2|Bacteria,4P1C5@976|Bacteroidetes,2FX1Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2570974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CKVGDEVQLLGLGEDKK MGYG000001770_01653;MGYG000002293_00521;MGYG000002603_01782;MGYG000003374_00521;MGYG000002080_00527;MGYG000003697_01485 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0050@1|root,COG0050@2|Bacteria,4P1C5@976|Bacteroidetes,2FX1Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 129450 0 203036 417327 199224 329032 373722 242891 159394 199607 194343 170699 303506 0 145043 0 289193 311333 0 208776 0 223329 350495 165522 465580 538957 0 236662 248751 0 232774 488359 239861 193505 233007 235124 435125 0 231089 0 0 0 0 86284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 201035 0 0 0 0 0 0 0 0 243156 0 0 0 0 331278 0 279670 0 0 247921 0 0 0 0 0 0 0 0 0 0 2583797 0 12155910 2489765 4222638 7316736 2341933 3475176 3057108 2371359 8455709 3184080 4228978 0 3370047 4845646 2108129 11261588 0 2134066 0 7791786 17663026 6053935 2656981 3333928 0 10009376 2120707 0 4024731 4813348 6777651 3416331 4049359 3364547 3216011 6648571 0 0 264996 510832 388723 133632 454352 399006 272423 0 0 132420 0 0 217687 0 0 0 0 536026 0 276826 568182 338479 369096 436410 0 0 0 0 0 163556 0 550528 351368 318294 0 96870 -(Pyro-carbamidomethyl)CLAPLAK MGYG000003589_01892;MGYG000002999_00356;MGYG000004468_00660;MGYG000002540_02142;MGYG000000375_01483;MGYG000004734_01400;MGYG000001783_01519;MGYG000003697_01698;MGYG000002057_00658;MGYG000000390_01195;MGYG000000074_00883;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002834_00628;MGYG000004756_01346;MGYG000002007_00386;MGYG000001692_02867;MGYG000002944_01470;MGYG000001345_01069;MGYG000002438_00285;MGYG000002026_00895;MGYG000003110_00098;MGYG000001562_00044;MGYG000004464_00783;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000000111_00274;MGYG000004536_01441;MGYG000003372_00674;MGYG000001448_01713;MGYG000004779_01244;MGYG000000243_01331;MGYG000002506_01169;MGYG000000273_02725;MGYG000002275_01823;MGYG000003469_01436;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000001334_01647;MGYG000003643_00817;MGYG000004658_00366;MGYG000004479_00217;MGYG000000044_01948;MGYG000003312_01022;MGYG000004526_01607;MGYG000002006_01638;MGYG000001445_01532;MGYG000001749_01249;MGYG000002455_02200;MGYG000001356_02656;MGYG000004487_00117;MGYG000004794_00985;MGYG000001546_00360;MGYG000002494_01669;MGYG000003542_01626;MGYG000000423_01499;MGYG000000421_00908;MGYG000001608_00559;MGYG000000412_01371;MGYG000001489_03093;MGYG000004638_00838;MGYG000000377_02142;MGYG000000445_00706;MGYG000001302.1_00095;MGYG000002556_00846;MGYG000003202_00946;MGYG000004411_00321;MGYG000002095_00148;MGYG000003681_00790;MGYG000000003_00712;MGYG000000097_00328;MGYG000002933_02039;MGYG000004482_00387;MGYG000000196_00479;MGYG000004757_00364;MGYG000001643_00773;MGYG000001661_02632;MGYG000003819_01468;MGYG000002549_00455;MGYG000000467_01930;MGYG000001337_01464;MGYG000002737_00455;MGYG000001789_00244;MGYG000002293_01263;MGYG000003155_00741;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002905_02083;MGYG000000941_01985;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.2872340425531915 976|Bacteroidetes 0.6170212765957447 G 0.6063829787234043 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8723404255319149 gap 0.9468085106382979 - 0.8936170212765957 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9468085106382979 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 118361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579400 0 0 0 0 528580 0 0 0 457941 129906 0 0 0 0 0 0 0 129921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159780 0 0 0 0 0 0 0 0 0 329838 0 0 0 0 0 0 0 0 0 136287 0 0 374376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101017 0 0 0 0 0 0 0 0 0 0 0 0 0 273598 0 0 0 0 0 613824 0 0 1052884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2406692 0 0 0 0 0 0 0 0 0 2417322 0 0 0 1014698 1200771 0 0 0 0 997652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290631 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CLAPMADALNK MGYG000003694_01737;MGYG000002974_01418;MGYG000001683_01827;MGYG000003374_01118;MGYG000000271_03250;MGYG000001319_00348;MGYG000000262_01195;MGYG000000404_00344;MGYG000003812_01036;MGYG000002517_01026;MGYG000000153_00303;MGYG000001652_01009;MGYG000000489_00503;MGYG000001299_00204;MGYG000001439_00571;MGYG000004707_01697;MGYG000000077_00219 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6470588235294118 186801|Clostridia 0.8235294117647058 G 0.8235294117647058 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7647058823529411 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 120167 0 140525 220426 272513 0 0 370024 387810 430593 0 0 0 350057 521278 189367 348899 0 452299 448052 0 0 0 0 0 364997 325259 0 0 329982 0 0 157200 0 0 0 277755 212704 0 0 0 69539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199909 0 312284 230094 122971 0 0 0 164493 0 0 0 0 0 361299 168179 180478 0 193952 306762 0 0 0 0 0 0 154994 0 0 435219 0 0 370015 0 0 0 170019 438318 1199585 0 676975 2887737 1100570 0 0 1551981 1995381 1296308 0 0 0 1833694 1784180 1458635 1865386 0 1691565 1952187 0 0 0 0 0 1243426 1928082 0 0 1649261 0 0 848980 0 0 0 1687706 853771 377327 0 232213 0 232086 0 0 139788 154516 442840 0 0 0 561404 485999 207594 449715 0 368552 349665 0 0 0 0 0 375029 330087 0 0 203071 0 0 135166 0 0 0 396857 327115 -(Pyro-carbamidomethyl)CLGGFEEGIHVSR MGYG000000262_02240 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,25VHE@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 248840 389672 0 292827 0 256917 0 255326 0 400392 0 0 400940 0 276759 462255 0 0 0 0 0 257905 0 0 0 0 0 0 0 295576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134990 173887 0 0 0 166617 0 0 0 0 189905 0 188089 0 1782468 1403324 0 2015717 0 1333105 0 1264828 0 1167072 0 0 1055971 0 1756744 1173178 0 0 0 0 0 2117571 0 291169 1487783 1651074 1694211 0 0 1123752 0 0 0 0 1650339 0 1093285 0 0 141616 0 212136 0 0 0 0 0 295913 0 0 320712 0 0 579350 0 0 0 0 0 230387 0 0 139643 0 228518 0 0 0 0 0 0 0 0 0 0 0 0 244280 0 226457 0 471533 0 167712 0 0 0 0 165409 0 334816 452877 0 0 0 0 0 441508 0 352311 97907 153429 0 0 0 197287 0 0 0 0 174606 0 352188 0 -(Pyro-carbamidomethyl)CLGVDDRK MGYG000001683_00453 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Frisingicoccus|s__|m__MGYG000001683 1.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,27J24@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Amidohydrolase family 1.0 nagA 1.0 - 1.0 3.5.1.25 1.0 ko:K01443 1.0 ko00520,ko01130,map00520,map01130 1.0 - 1.0 R02059 1.0 RC00166,RC00300 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_1 1.0 - 1.0 CE9 1.0 CE9 1.0 CE9 1.0 N-acetylglucosamine-6-phosphate deacetylase. - Formerly EC 3.5.1.80. H2O + N-acetyl-D-glucosamine 6-phosphate = acetate + D-glucosamine 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CLIITGAGEK MGYG000001315_01870;MGYG000000262_02232;MGYG000000077_02465 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,25UX1@186806|Eubacteriaceae 0.6666666666666666 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.6666666666666666 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 479192 0 235283 137172 0 0 0 0 0 271483 0 0 0 202380 700444 0 225570 0 583719 697050 568972 0 0 0 751137 546486 205078 0 0 197725 0 0 139353 612952 489138 0 327311 0 204465 0 118385 673623 0 0 444571 0 0 382703 0 0 0 400173 507939 0 370309 0 202252 1079119 449816 0 0 0 587714 216326 624352 0 0 710324 0 0 102428 632287 346544 0 525377 0 3005012 0 678758 4738865 0 0 819972 0 0 2495872 0 0 0 2302308 3144659 0 2131085 0 2722197 2756355 1824012 0 0 0 3415279 2795111 3401548 0 0 1738572 0 0 1623369 3452101 3245772 0 2319342 661722 893809 0 690272 0 0 0 1203387 0 0 1055415 0 0 0 966395 780315 0 1345170 0 683030 1328874 258736 0 0 0 563771 481630 886383 0 0 700746 0 0 1018161 209114 818221 0 551390 827731 168238 0 727710 328171 0 0 416658 0 0 326784 0 0 0 421499 261503 0 242375 0 354555 0 469599 0 0 0 359019 209377 238393 0 0 84526 0 0 1298100 342561 346494 0 179870 559960 -(Pyro-carbamidomethyl)CLILTGAGEK MGYG000001315_01870;MGYG000003311_01584;MGYG000000262_02232;MGYG000000077_02465;MGYG000001777_01056;MGYG000001319_02237 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,27IZZ@186928|unclassified Lachnospiraceae 0.3333333333333333 186801|Clostridia 1.0 I 1.0 Enoyl-CoA hydratase/isomerase 0.5 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 213147 0 0 0 0 0 729976 652499 0 0 0 0 984260 0 0 0 0 0 0 0 381442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 861378 0 542851 0 0 0 746619 0 0 368188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 847555 0 0 0 0 0 0 0 3175217 0 0 0 0 0 2850974 0 0 0 0 0 0 0 0 0 0 0 0 0 3803619 0 0 0 0 0 0 0 0 0 2415266 0 0 0 0 0 0 0 0 0 1370001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CLITALSELNQPR MGYG000002934_01790;MGYG000000404_01798;MGYG000002517_00543 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.6666666666666666 186801|Clostridia 0.6666666666666666 C 1.0 electron transfer flavoprotein 0.6666666666666666 etfB 1.0 - 0.6666666666666666 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 228781 0 528705 121993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99359 0 0 0 0 0 0 363414 0 0 0 0 0 213178 0 197152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164115 0 0 0 3036456 0 155288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1661751 0 0 0 5454047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7313742 0 0 0 0 0 0 0 0 0 0 3014047 0 12628995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6998271 0 0 0 0 0 0 0 0 0 0 16041173 20936132 -(Pyro-carbamidomethyl)CLLNQEDIMDGKK MGYG000001346_00649;MGYG000000243_02465;MGYG000003367_01580;MGYG000004876_02408;MGYG000000029_01191;MGYG000004797_01413;MGYG000002438_01052;MGYG000002478_01739 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 0.875 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 545000 0 0 0 0 0 0 0 0 0 1358327 0 0 1434675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1026553 0 0 0 0 743399 0 0 321890 0 0 0 0 0 0 0 0 0 466292 0 0 320895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468535 0 0 0 0 0 0 0 336811 0 0 0 0 0 0 0 0 0 903608 0 0 720608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519155 0 0 0 0 381615 0 0 510534 0 0 0 0 0 0 0 0 0 783355 0 0 672460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407299 0 0 0 0 462927 0 0 355251 0 0 0 0 0 0 0 0 0 1165392 0 0 772764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CLLYAINGGKDEK MGYG000000251_01975;MGYG000000417_02137;MGYG000003702_02236;MGYG000004039_00572;MGYG000000018_02208;MGYG000000217_01657;MGYG000000231_00514 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,27J0U@186928|unclassified Lachnospiraceae 0.5714285714285714 186801|Clostridia 1.0 C 1.0 Pyruvate formate lyase-like 0.5714285714285714 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2508198 0 0 0 0 2115784 0 0 0 0 2283283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 631531 0 0 0 0 965612 0 0 0 0 754690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421755 0 0 0 0 633245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 819370 0 0 0 0 597914 0 0 0 0 302751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331316 0 0 0 0 493850 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CLPGSVADDRK MGYG000004464_00921;MGYG000000196_00899;MGYG000004763_01967;MGYG000004493_00376;MGYG000000045_01847;MGYG000001415_02505;MGYG000004797_02907;MGYG000001423_03082;MGYG000000479_02090;MGYG000001925_01569;MGYG000001346_01121;MGYG000000215_01600;MGYG000002478_02896 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.46153846153846156 976|Bacteroidetes 0.6923076923076923 S 1.0 Psort location Cytoplasmic, score 8.96 0.6153846153846154 - 0.9230769230769231 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 2368328 0 0 0 1521131 0 0 0 1687583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 778930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CLQEAQAQR MGYG000001783_01717;MGYG000000029_01548;MGYG000003681_00508;MGYG000003701_03757;MGYG000001364_03472;MGYG000001346_01330;MGYG000003312_02085;MGYG000004185_00718;MGYG000000054_03790;MGYG000002275_00363;MGYG000002478_01473;MGYG000004797_02540;MGYG000003252_02925;MGYG000001489_04121;MGYG000000013_01585;MGYG000000196_02857;MGYG000004757_01054;MGYG000004571_00850;MGYG000000236_02278;MGYG000000243_01844;MGYG000001345_00716;MGYG000002549_02435;MGYG000001461_03704;MGYG000001599_01758;MGYG000003922_02564;MGYG000002438_03363;MGYG000001313_02809;MGYG000000174_02073 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FN0E@200643|Bacteroidia,4AN4E@815|Bacteroidaceae 0.6071428571428571 976|Bacteroidetes 1.0 H 1.0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA 1.0 kbl 1.0 - 1.0 2.3.1.29 1.0 ko:K00639 1.0 ko00260,map00260 1.0 - 1.0 R00371 1.0 RC00004,RC00394 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine C-acetyltransferase. 2-amino-3-ketobutyrate coenzyme A ligase. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism 1.0 none 1.0 1180243 1620779 2470779 1410032 1312226 1186012 1169438 1599548 1012951 839307 922365 1546448 1480961 1379096 1421422 1332199 1431515 808856 1130022 303569 1413212 1536626 1020929 2301058 0 1241832 1656549 1290546 1385581 1699860 2646672 1514995 3067088 1455741 1644550 1211180 1693467 2190046 1261306 943652 1599988 1727152 1480478 1292017 1296672 1515806 1615606 1791994 1567706 1704897 1467583 1644313 1869277 1554443 1160153 929531 1480275 1286984 1403281 1411447 1704935 1037109 0 1283241 1449410 1436646 1096932 1650220 1032121 1465429 1429922 1349640 1671452 1221036 1294524 1363478 1074100 1176334 1225432 1864577 1777983 1365389 1418603 1098463 1169041 1121341 1295896 1105530 634973 1180614 993416 1322353 1153589 2036619 1213777 955502 826345 701751 1540551 1754032 0 1500229 1103739 1522899 1407448 961464 1382233 1208179 1373307 705442 1467458 1627242 1246501 1265606 0 0 224525 0 0 0 0 0 0 0 348246 427573 547563 0 0 0 0 0 0 0 874573 0 217408 225864 0 0 0 0 0 0 0 0 0 658709 0 0 0 0 0 0 249598 471205 111511 924398 936016 986568 1191960 551767 926292 485419 1153975 1030933 0 824971 669954 1495343 672792 998076 826520 774543 1378751 1382295 0 739994 597758 1188154 0 1630430 966375 1310571 603824 1041840 413823 721159 1325297 976102 -(Pyro-carbamidomethyl)CLSAGSNESHSAIIAR MGYG000002494_03341 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1080@1|root,COG1925@1|root,COG3412@1|root,COG1080@2|Bacteria,COG1925@2|Bacteria,COG3412@2|Bacteria,1MUT8@1224|Proteobacteria,1RRCZ@1236|Gammaproteobacteria,3WVVD@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 PEP-utilising enzyme, N-terminal 1.0 dhaM 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006476,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033554,GO:0033558,GO:0034983,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0047324,GO:0050896,GO:0051716,GO:0071704,GO:0098732,GO:0140096,GO:1901564 1.0 2.7.1.121 1.0 ko:K05881 1.0 ko00561,map00561 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000,ko02000 1.0 - 1.0 - 1.0 iECs_1301.ECs1703,iSF_1195.SF1201,iS_1188.S1285,iUTI89_1310.UTI89_C1391,iZ_1308.Z1969 1.0 EIIA-man,PEP-utilisers_N,PEP-utilizers,PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330930 0 0 0 0 260469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CLSC(Carbamidomethyl)FAC(Carbamidomethyl)VER MGYG000001338_01863;MGYG000001689_04268;MGYG000004735_02511;MGYG000000142_01113;MGYG000000216_03384;MGYG000000184_02633;MGYG000000201_01324;MGYG000002989_01366;MGYG000002042_01111;MGYG000000806_00466;MGYG000000251_01182;MGYG000000050_02100 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1150@1|root,COG1150@2|Bacteria,1V27J@1239|Firmicutes,24FU5@186801|Clostridia,3Y1I7@572511|Blautia 0.3333333333333333 186801|Clostridia 0.75 C 0.8333333333333334 4Fe-4S dicluster domain 0.5833333333333334 - 1.0 - 1.0 - 0.6666666666666666 - 0.5 - 0.9166666666666666 - 0.9166666666666666 - 0.6666666666666666 - 0.9166666666666666 - 0.5 - 0.8333333333333334 - 1.0 - 1.0 Fer4_10,Fer4_8 0.4166666666666667 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.9166666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 700610 912146 0 0 0 0 444306 -(Pyro-carbamidomethyl)CLTADEAANAPESTK MGYG000001627_00502;MGYG000003937_00374 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 765062 0 0 0 0 0 0 0 0 0 468329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CLVDIARK MGYG000000179_03143 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,26889@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Arginosuccinate synthase 1.0 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Fluid shear stress and atherosclerosis;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 404372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 171872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907057 0 1491845 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CLVEGAIENSYTK MGYG000000223_01696 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG1486@1|root,COG1486@2|Bacteria,2GK80@201174|Actinobacteria,4CV7D@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 Family 4 glycosyl hydrolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_4,Glyco_hydro_4C 1.0 3.2.1.122 1.0 GH4 1.0 GH4 1.0 GH4 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 713252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 315995 0 0 0 0 0 0 0 1305871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 626980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CMDAAAHVR MGYG000000077_00330 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum soehngenii|m__MGYG000000077 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 534677 0 0 0 1012309 0 0 0 671551 0 0 0 0 0 648607 0 0 0 0 0 1014888 0 0 0 0 0 0 206979 0 0 0 0 0 0 0 0 0 0 890541 0 997461 0 719173 1661928 0 0 599975 0 0 0 0 0 0 0 0 0 0 0 348825 0 855948 0 0 0 0 1385934 0 0 0 0 0 0 0 0 0 0 2408897 0 3703762 0 2591067 714345 0 0 1863874 0 0 0 0 0 2006707 0 0 0 0 0 3612803 0 1399712 0 0 0 0 408114 0 0 0 0 0 0 0 0 0 0 5125429 0 4127194 0 5451393 4445793 0 0 7678038 0 0 0 0 0 6803081 0 0 0 0 0 5604590 0 4828540 0 0 0 0 5184512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CMGANQQQYLK MGYG000002485_01479 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,378RN@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 538373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CNIGTIGHVDHGK MGYG000001615_01716;MGYG000000171_02844;MGYG000002279_01932;MGYG000000201_03875;MGYG000000245_03248;MGYG000001688_04229;MGYG000000280_01200;MGYG000001714_01291;MGYG000000198_01165;MGYG000000271_03365;MGYG000004804_01395;MGYG000001315_01207;MGYG000000133_02991;MGYG000001602_02247;MGYG000001310_01963;MGYG000003273_00234;MGYG000000140_01590;MGYG000001065_02730;MGYG000002528_01098;MGYG000002609_01147;MGYG000002202_00030;MGYG000000179_00920;MGYG000000216_02406;MGYG000000217_01428;MGYG000002517_00205;MGYG000002290_01325;MGYG000001531_00906;MGYG000004296_01668;MGYG000001607_01045;MGYG000001141_02439;MGYG000001652_01300;MGYG000000127_03982;MGYG000003425_03741;MGYG000000251_00064;MGYG000001338_03373;MGYG000002670_00364;MGYG000000139_00697;MGYG000000233_00807;MGYG000000142_00171;MGYG000000255_02009;MGYG000000404_00531;MGYG000004087_00551;MGYG000000242_00282;MGYG000000018_00453;MGYG000000187_02029;MGYG000000202_03457;MGYG000001606_01669;MGYG000000212_03313;MGYG000001698_04050;MGYG000004558_00415;MGYG000000032_01232;MGYG000001777_01732;MGYG000002837_02416;MGYG000000193_02083;MGYG000000445_01370;MGYG000002212_00196;MGYG000000249_00026;MGYG000004799_01385;MGYG000004630_01824;MGYG000002286_02469;MGYG000001814_01592;MGYG000000262_00030;MGYG000002772_01895;MGYG000002492_00344;MGYG000001617_01406;MGYG000003514_00785;MGYG000002052_00232;MGYG000003013_00349;MGYG000000206_00901;MGYG000004733_01211;MGYG000001319_01764 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.2535211267605634 186801|Clostridia 0.9577464788732394 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9859154929577465 tuf 1.0 - 0.971830985915493 - 1.0 ko:K02358 0.9859154929577465 - 0.9859154929577465 - 0.9859154929577465 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9859154929577465 - 0.9859154929577465 - 1.0 - 0.9859154929577465 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9859154929577465 none 1.0 0 312121 430402 355920 748856 380431 219923 0 0 640556 0 0 340715 0 1918560 492928 338263 1777344 239510 931890 0 653667 694134 129710 0 0 0 1126744 526548 0 155778 499829 220565 0 0 0 0 296219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 202234 175696 208757 0 238867 211400 0 0 214254 0 0 213780 0 324083 0 183904 0 293800 140905 0 219736 0 113117 0 0 0 0 188443 0 205384 185348 244533 0 0 0 0 294900 0 3063411 1837412 2400795 2191377 1817668 1802763 0 0 2334836 0 0 1344318 0 1950460 2559000 3032616 1478841 1986098 2844467 0 1764078 1063521 1851395 0 0 0 3346435 3724025 0 3557461 1788718 2251286 0 0 0 0 3287018 0 0 0 308861 0 0 303271 0 0 424815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157352 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CNVGDTVKR MGYG000002438_00415 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG4770@1|root,COG4770@2|Bacteria,4NSWV@976|Bacteroidetes,2FRYI@200643|Bacteroidia,22YBV@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Biofilm PGA synthesis protein PgaD 1.0 mmdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1081097 0 0 0 0 0 0 0 0 1974143 0 0 0 0 206311 0 0 0 347383 0 0 0 0 0 0 442340 0 303844 0 0 0 0 0 0 0 0 0 0 356207 0 0 0 0 0 0 0 0 665852 0 0 0 0 294661 0 0 0 469924 0 0 0 0 0 0 271965 0 136878 0 0 0 0 0 0 354943 0 0 0 687567 0 0 0 0 0 0 0 0 1782109 0 0 0 0 513736 0 0 0 652047 0 0 0 0 0 0 327659 0 1092203 0 0 0 0 0 0 1174992 0 0 0 2344709 0 0 0 0 0 0 0 0 2636796 0 0 0 0 1392959 0 0 0 3465620 0 0 0 0 0 0 1569138 0 -(Pyro-carbamidomethyl)CNYEAVKER MGYG000000179_05289 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248IC@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Glycosyl hydrolases family 31 1.0 yicI 1.0 - 1.0 3.2.1.177,3.2.1.199 1.0 ko:K01811,ko:K15922 1.0 - 1.0 - 1.0 R00802,R11543 1.0 RC00028,RC00059,RC00077,RC00451 1.0 ko00000,ko01000 1.0 - 1.0 GH31 1.0 - 1.0 Glyco_hydro_31 1.0 - 1.0 GH31 1.0 GH31 1.0 GH31 1.0 alpha-D-xyloside xylohydrolase. | sulfoquinovosidase. alpha-xylosidase. The enzyme catalyzes hydrolysis of a terminal, unsubstituted xyloside at the extreme reducing end of a xylogluco-oligosaccharide.-!-Representative alpha-xylosidases from glycoside hydrolase family 31 utilize a two-step (double-displacement) mechanism involving a covalent glycosyl-enzyme intermediate, and retain the anomeric configuration of the product. | The enzyme, characterized from the bacteria Escherichia coli and Pseudomonas putida, hydrolyzes terminal non-reducing alpha- sulfoquinovoside residues in alpha-sulfoquinovosyl diacylglycerides and alpha-sulfoquinovosyl glycerol. Hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose. | a 6-sulfo-alpha-D-quinovosyldiacylglycerol + H2O = 6-sulfo-alpha-D- quinovose + a 1,2-diacyl-sn-glycerol. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290557 0 0 0 0 0 0 0 0 958345 0 0 0 0 0 0 0 1146699 1410962 0 1081003 0 942075 1019059 0 715861 0 958732 737576 1244978 0 0 0 0 1544287 944396 0 0 867419 0 0 0 742042 0 942727 1281800 0 -(Pyro-carbamidomethyl)CPAGISHPMVGLLAR MGYG000000142_01107;MGYG000002298_01727;MGYG000001652_00112;MGYG000004201_01235;MGYG000000200_00050;MGYG000001698_00113;MGYG000000031_01423;MGYG000004839_00388;MGYG000000194_00425;MGYG000003335_01021;MGYG000002202_00763;MGYG000002946_00022;MGYG000004296_00035;MGYG000000184_02627;MGYG000001338_01870;MGYG000001689_04274;MGYG000004735_02505;MGYG000000216_03378;MGYG000004733_00383;MGYG000002989_01360;MGYG000000140_03070 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia 0.47619047619047616 186801|Clostridia 1.0 C 0.8095238095238095 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein 0.47619047619047616 - 1.0 - 1.0 - 0.5238095238095238 - 0.5238095238095238 - 0.5238095238095238 - 0.5238095238095238 - 0.5238095238095238 - 0.5238095238095238 - 0.5238095238095238 - 1.0 - 1.0 - 1.0 FAD_binding_2,Fer4,Fer4_10,Fer4_7,Pyr_redox_2 0.47619047619047616 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.5238095238095238 0.5238095238095238 0.5238095238095238 0.5238095238095238 0.5238095238095238 none 1.0 0 1508162 1269838 0 1775344 0 0 0 0 0 1467143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762364 1762631 845040 0 0 0 0 1003624 0 2676878 472668 0 1154858 0 0 0 0 0 1139435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3091039 819234 613911 0 0 0 0 728897 0 2987826 620550 0 287623 0 0 0 0 0 236320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742811 2024002 1032638 0 0 0 0 593592 0 827899 264172 0 575281 0 0 0 0 0 256290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577716 680900 0 0 0 0 0 0 0 4868600 3007437 0 1178333 0 0 0 0 0 1521492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3924077 5680239 4733206 0 0 0 0 2757271 -(Pyro-carbamidomethyl)CPGSDEFTLVNANTGK MGYG000001302.1_01986 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391242 1169332 0 0 456454 749337 564328 0 0 0 781563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475439 655272 0 0 0 0 0 0 0 0 0 0 0 888972 825154 0 0 545235 833860 600028 0 0 0 719444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388319 370667 0 0 0 0 0 0 0 0 0 0 0 544866 787258 0 0 0 1297796 0 0 0 0 425220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 598788 0 0 0 0 0 0 0 0 0 0 0 800485 555147 0 0 0 889968 346546 0 0 0 758940 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CPLPGTVLSVK MGYG000000074_02437;MGYG000000003_01112 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG4770@1|root,COG4770@2|Bacteria,4NSWV@976|Bacteroidetes,2FRYI@200643|Bacteroidia,22UGJ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Biotin-requiring enzyme 1.0 mmdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 114973 0 0 0 0 0 0 0 0 0 83265 0 0 0 0 0 0 157184 0 0 0 0 0 0 0 0 0 386891 0 0 111674 0 0 0 0 0 0 0 245052 0 0 0 0 0 0 0 0 0 77681 0 0 0 0 0 0 357608 0 0 0 0 0 0 0 0 0 177351 0 0 139678 0 0 0 0 339659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80066 0 0 0 0 0 0 0 0 0 0 694486 0 0 0 0 0 0 0 0 0 1012239 0 0 0 0 0 0 1507619 0 0 0 0 0 0 0 0 0 1683504 0 0 286114 0 0 0 0 794904 -(Pyro-carbamidomethyl)CPNHVEVSHIR MGYG000001300_01521;MGYG000003166_01563 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,3WH9C@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 DAK2 domain fusion protein YloV 1.0 - 1.0 - 1.0 - 1.0 ko:K07030 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Dak1_2,Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 200719 0 0 0 0 0 139559 0 0 0 305891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478857 0 0 0 0 0 0 0 0 0 0 375388 0 901265 0 0 0 0 0 1304528 0 0 0 852490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1132522 0 0 0 0 0 0 0 0 0 0 1105191 0 0 0 0 0 0 0 414053 0 0 0 281899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284653 0 0 0 0 0 0 0 0 0 0 282054 0 533924 0 0 0 0 0 852040 0 0 0 592384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476382 0 0 0 0 0 0 0 0 0 0 524052 0 94361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361352 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CPTAHIDRK MGYG000002492_01293 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 - 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 63956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86807 0 0 0 0 0 0 0 446466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253133 0 0 0 0 235780 0 0 2144334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2213239 0 0 0 0 2391957 0 0 371809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 510649 0 0 0 0 692875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CPTQIHNFATDDELK MGYG000001338_01046 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG4656@1|root,COG4656@2|Bacteria,1TS9H@1239|Firmicutes,24DQ7@186801|Clostridia,3XYYU@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Methylene-tetrahydrofolate reductase C terminal 1.0 metV 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 iHN637.CLJU_RS18525 1.0 MTHFR_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 453300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 597923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 954354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CPVYQNVDALPHTDPAEIK MGYG000004797_03294;MGYG000004876_02965;MGYG000002171_00714;MGYG000004720_00652;MGYG000000196_04611;MGYG000004823_01134;MGYG000000243_00899;MGYG000001345_02939;MGYG000000013_03230;MGYG000002560_01276 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia,4AK7G@815|Bacteroidaceae 0.9 976|Bacteroidetes 1.0 I 1.0 malonyl CoA-acyl carrier protein transacylase 1.0 fabD 1.0 - 1.0 2.3.1.39 1.0 ko:K00645 1.0 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 1.0 M00082 1.0 R01626,R11671 1.0 RC00004,RC00039,RC02727 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 Acyl_transf_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 [acyl-carrier-protein] S-malonyltransferase. MCAT. Essential, along with EC 2.3.1.38, for the initiation of fatty-acid biosynthesis in bacteria.-!-Also provides the malonyl groups for polyketide biosynthesis.-!-The product of the reaction, malonyl-ACP, is an elongation substrate in fatty-acid biosynthesis.-!-In Mycobacterium tuberculosis, holo-ACP (the product of EC 2.7.8.7) is the preferred substrate.-!-This enzyme also forms part of the multienzyme complexes EC 4.1.1.88 and EC 4.1.1.89.-!-Malonylation of ACP is immediately followed by decarboxylation within the malonate-decarboxylase complex to yield acetyl-ACP, the catalytically active species of the decarboxylase.-!-In the enzyme from Klebsiella pneumoniae, methylmalonyl-CoA can also act as a substrate but acetyl-CoA cannot whereas the enzyme from Pseudomonas putida can use both as substrates.-!-The ACP subunit found in fatty-acid biosynthesis contains a pantetheine-4'-phosphate cofactor; that from malonate decarboxylase also contains pantetheine-4'-phosphate but in the form of a 2'-(5-triphosphoribosyl)-3'-dephospho-CoA cofactor. holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis;Prodigiosin biosynthesis;Metabolic pathways;Fatty acid metabolism 1.0 none 1.0 0 0 1468648 0 0 0 0 0 0 0 0 0 1515772 0 0 1425166 0 0 0 706829 0 0 0 0 0 0 0 0 0 901478 0 0 1675618 0 0 0 0 1386469 0 0 488112 0 0 0 0 0 0 0 0 0 1255840 0 0 1085958 0 0 0 229670 0 0 0 0 0 0 0 0 0 769015 0 0 524437 0 0 0 0 595991 0 0 501998 0 0 0 0 0 0 0 0 0 731677 0 0 398983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141341 0 0 0 0 0 0 453748 0 0 0 0 0 0 0 0 0 639940 0 0 0 0 0 0 0 349338 -(Pyro-carbamidomethyl)CQAGFC(Carbamidomethyl)SPR MGYG000002298_00538;MGYG000000038_01495;MGYG000002993_00207;MGYG000000404_00180;MGYG000004552_00557;MGYG000001619_01503;MGYG000002312_03079;MGYG000000255_01681;MGYG000001186_01771;MGYG000000164_01752;MGYG000000271_03444;MGYG000001683_00852;MGYG000002517_00257;MGYG000002036_00234;MGYG000001627_02087;MGYG000002517_00473;MGYG000002059_01429;MGYG000000489_00238;MGYG000000154_01590;MGYG000000153_02080;MGYG000000076_01007;MGYG000000245_01076;MGYG000000205_00110;MGYG000003074_00570;MGYG000000127_02775;MGYG000002279_02522;MGYG000001315_01114;MGYG000004271_01228;MGYG000000212_00378;MGYG000002105_01104 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 0.3333333333333333 186801|Clostridia 0.9666666666666667 S 0.4666666666666667 FAD dependent oxidoreductase 0.5 - 1.0 - 1.0 1.1.5.3 0.9666666666666667 ko:K00111 0.9666666666666667 ko00564,ko01110,map00564,map01110 0.9666666666666667 - 1.0 R00848 0.9666666666666667 RC00029 0.9666666666666667 ko00000,ko00001,ko01000 0.9666666666666667 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 0.9666666666666667 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 0.9666666666666667 0.9666666666666667 0.9666666666666667 0.9666666666666667 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 0.9666666666666667 none 1.0 1733066 1054860 1029240 1259332 1454658 1454285 1598919 2248693 2197284 2358474 1413524 1763756 1488935 1480309 2158529 1369047 1436701 0 2109025 2257880 1742384 1216178 0 628124 2413241 1972213 1662345 0 1453468 1848562 570522 783547 681628 1408028 1887809 1363889 1402404 774764 518183 552966 219983 607738 363362 229258 559328 461195 342456 461998 306744 236371 140849 365749 380866 265874 335648 0 635166 543026 381380 0 0 519874 552747 410093 446661 0 733906 376138 469951 448698 356664 584406 443989 417261 385676 359217 503428 0 0 317819 0 0 344778 501434 0 349187 0 253572 0 364740 448684 0 259213 0 488826 767767 0 0 0 0 496440 559412 444501 0 164667 404420 0 152612 295872 388313 459168 419494 525530 0 2253708 327350 491478 1893893 897096 676406 1167057 2347134 2507969 1260607 717447 1023385 625330 2288577 2376621 866817 1536399 0 2101320 2042184 1439190 0 0 0 3078984 2104130 2363391 0 627234 1814005 442823 917931 617446 1332749 2231768 2360334 2169111 549128 1604080 969974 1891072 329853 1066518 1774959 2083827 1492198 1900516 2859389 1823396 1841167 749309 2731188 2286811 1079200 1744666 0 1942320 1186721 1658090 1086454 0 1430452 2689726 1972758 2370641 0 702929 1378124 1519133 546493 2087867 2353191 1829647 3180123 3254903 2071569 -(Pyro-carbamidomethyl)CQAGFC(Carbamidomethyl)TPR MGYG000001564_01807;MGYG000000077_00890;MGYG000004691_01133;MGYG000002445_00671;MGYG000002946_03411;MGYG000001199_03274;MGYG000001493_05221;MGYG000001622_01941;MGYG000002912_01338;MGYG000000179_02173;MGYG000000233_01585;MGYG000001311_02981;MGYG000000262_00167;MGYG000000198_04022 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,21XTX@1506553|Lachnoclostridium 0.5714285714285714 186801|Clostridia 1.0 S 0.5714285714285714 FAD dependent oxidoreductase 0.8571428571428571 lhgO 0.42857142857142855 - 1.0 1.1.5.3 0.8571428571428571 ko:K00111 0.8571428571428571 ko00564,ko01110,map00564,map01110 0.8571428571428571 - 0.8571428571428571 R00848 0.8571428571428571 RC00029 0.8571428571428571 ko00000,ko00001,ko01000 0.8571428571428571 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 0.8571428571428571 none 1.0 930621 0 0 721109 0 404507 0 0 744546 779029 0 0 0 885914 940858 320888 451748 0 0 1166941 0 499859 0 288856 0 776280 653434 0 852303 862454 0 0 0 0 795196 748687 917885 0 443939 0 0 581864 0 230347 0 0 533293 470319 0 0 0 408313 433072 90894 100551 0 0 514481 0 90392 0 291228 0 431156 566633 0 506348 351017 0 0 0 0 524984 465770 470299 0 1482795 0 0 1302685 0 490193 0 0 808966 889999 0 0 0 1026411 1301391 851756 1058051 0 0 1427409 0 1060807 0 372195 0 1081417 1384293 0 920920 1049009 0 0 0 0 641821 853466 773880 0 386831 0 0 465408 0 411463 0 0 440402 600111 0 0 0 388682 253975 362977 466031 0 0 446982 0 335994 0 0 0 265645 430818 0 330179 273825 0 0 0 0 259775 329855 281455 0 1634971 0 0 1321847 0 734014 0 0 1497510 1321643 0 0 0 2341048 1609213 541478 1281515 0 0 1315511 0 833848 0 1049002 0 1560474 1625140 0 1771650 894429 0 0 0 0 654902 1432815 1738722 0 -(Pyro-carbamidomethyl)CQDILKK MGYG000002478_02197 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1332186 0 326401 0 0 0 0 271240 0 0 0 0 299481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 700058 0 239322 0 0 0 0 481056 0 0 0 0 335835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 565131 0 314050 0 0 0 0 304749 0 0 0 0 305699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1229704 0 1345091 0 0 0 0 1059905 0 0 0 0 678944 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CQDTGTAIIHGEK MGYG000000215_02049;MGYG000002293_01379;MGYG000003697_00235;MGYG000003493_01720 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,4NE85@976|Bacteroidetes,2FNPE@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Catalyzes the reversible hydration of fumarate to (S)- malate 1.0 fumB 1.0 - 1.0 4.2.1.2 1.0 ko:K01676 1.0 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00374 1.0 R01082 1.0 RC00443 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fumerase,Fumerase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fumarate hydratase. fumarase. - (S)-malate = fumarate + H2O. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2518551 0 0 0 0 2410564 0 0 0 0 2083595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CQETGITIER MGYG000002494_03339 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2376@1|root,COG2376@2|Bacteria,1MVSR@1224|Proteobacteria,1RNRQ@1236|Gammaproteobacteria,3WVUW@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Dak1 domain 1.0 dhaK 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 1.0 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 1.0 ko:K00863,ko:K05878 1.0 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 1.0 M00344 1.0 R01011,R01012,R01059 1.0 RC00002,RC00015,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 1.0 Dak1,Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. | triokinase. | glycerone kinase. | FAD-AMP lyase (cyclizing). triose kinase. | dihydroxyacetone kinase. | FMN cyclase. While FAD was the best substrate tested the enzyme also splits ribonucleoside diphosphate-X compounds in which X is an acyclic or cyclic monosaccharide or derivative bearing an X-OH group that is able to attack internally the proximal phosphorus with the geometry necessary to form a P=X product; either a five-atom monocyclic phosphodiester or a cis-bicyclic phosphodiester-pyranose fusion.-!-The reaction is strongly inhibited by ADP or ATP but is unaffected by the presence of the product, cFMN. dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. | ATP + D-glyceraldehyde = ADP + D-glyceraldehyde 3-phosphate + H(+). | ATP + dihydroxyacetone = ADP + dihydroxyacetone phosphate + H(+). | FAD = AMP + H(+) + riboflavin cyclic-4',5'-phosphate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RIG-I-like receptor signaling pathway;Glycerolipid metabolism;Metabolic pathways;Fructose and mannose metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 274090 0 0 0 0 0 0 0 0 0 0 0 0 128265 0 0 0 0 0 0 0 0 0 0 0 0 0 3033889 4427940 4460422 2332505 3858928 8064920 4611438 2050543 3980134 5527901 0 2518515 1731017 4639226 3844485 2711244 6328907 0 7974401 0 5653059 10897142 0 8374593 5241899 4066113 3012525 0 7099905 5965643 1692345 2298300 4353328 2962323 2619828 2783091 3010535 3735024 0 0 0 0 0 0 0 0 0 0 0 0 0 314453 0 0 0 0 0 0 0 0 0 0 0 288464 0 0 0 0 0 0 0 0 0 0 0 0 0 693593 0 0 0 0 0 0 0 462288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343698 295450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CQGGFC(Carbamidomethyl)GPR MGYG000001365_00857;MGYG000004667_02863;MGYG000002223_00242;MGYG000000395_00387;MGYG000002528_01430;MGYG000001300_01090;MGYG000000615_00659;MGYG000003899_00568;MGYG000001339_00546;MGYG000003291_01075;MGYG000000121_02636;MGYG000002274_01878;MGYG000004732_01408;MGYG000002934_02590;MGYG000001616_00737;MGYG000001464_01654;MGYG000000080_03188;MGYG000002641_01322;MGYG000000028_00488;MGYG000002651_01302 domain d__Bacteria 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,3WH8P@541000|Ruminococcaceae 0.4 186801|Clostridia 0.7 C 0.75 FAD dependent oxidoreductase 0.85 glpA 0.7 - 1.0 1.1.5.3 0.9 ko:K00111 0.85 ko00564,ko01110,map00564,map01110 0.9 - 1.0 R00848 0.9 RC00029 0.9 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD,NAD_binding_8 0.7 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 0.9 0.9 0.9 0.9 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 0.9 none 1.0 742712 879645 1160444 851595 298418 938469 604684 0 739353 766796 527397 0 1068926 798741 606948 726981 728807 0 1715691 834983 267728 814983 0 601287 852387 818288 568140 0 563092 411242 600835 537835 932338 1266545 0 548930 488261 991046 1624134 2126484 1330292 1351868 970512 1771692 1869822 0 1672128 393362 655025 0 1010775 1644735 1169447 800757 1362975 0 2489629 1718039 222284 1075545 0 1844816 1794197 1374025 1664464 0 443471 1182620 1904086 1488560 1195976 1331192 0 1217755 1177343 1450410 676229 3500295 955455 0 367496 1103519 852974 0 779874 397878 931887 0 989648 624502 858456 1106162 961544 0 1072257 787040 1104023 3333965 0 787844 754074 610279 834297 0 1858347 454633 660434 2566855 1342773 1494845 0 370822 516205 908868 727124 1002450 1329905 714477 1174074 1168186 1534838 0 1245956 881075 875254 0 1410528 1076701 956748 878663 1010788 0 1356512 1174933 297285 933600 0 1038056 1320746 892588 959591 0 1969822 1231279 1331159 1307471 1564572 1167567 0 704451 978422 1373649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 836289 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CQKEEIFEK MGYG000002517_01956 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 Belongs to the UPF0237 family 1.0 - 1.0 - 1.0 - 1.0 ko:K07166 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ACT_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 439614 0 0 0 0 0 0 308068 0 0 0 0 0 0 0 0 0 0 0 476566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391882 0 0 0 0 0 0 0 0 0 0 0 0 2277674 0 0 0 0 0 0 3434613 2259079 0 0 0 0 0 3347437 0 0 0 0 0 0 0 0 0 3499451 2835671 2258262 0 0 0 0 0 0 0 0 0 3076655 0 1740472 0 0 0 0 0 0 1277149 1711145 0 0 0 0 0 2219467 0 0 0 0 0 0 0 0 0 1595948 1433781 1396338 0 0 0 0 0 0 0 0 0 2292674 0 -(Pyro-carbamidomethyl)CQPGSITC(Carbamidomethyl)HTK MGYG000002528_01098 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 427271 0 0 0 285944 0 0 0 0 0 0 0 0 0 193739 0 0 0 0 0 384649 0 0 259981 0 0 0 186289 0 0 290372 0 0 0 0 0 0 0 585843 0 0 0 358699 0 0 0 0 0 0 0 0 0 267789 0 0 0 0 0 0 0 0 763137 0 0 0 0 0 425492 245641 0 0 0 0 0 0 0 1681940 0 0 0 1594302 0 1040324 0 0 0 0 0 0 0 909879 0 0 1183684 0 1055166 2751964 0 1246643 1581598 0 0 0 3226126 0 700118 1411797 0 1161249 0 789800 0 0 0 1964482 0 0 0 796115 0 314066 0 0 0 0 0 0 0 761278 0 0 202907 0 338051 887061 0 783598 448427 0 0 0 4624590 0 1334837 1690131 0 0 0 348599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CQSPANLLK MGYG000002641_02188 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp003449675|m__MGYG000002641 1.0 COG1653@1|root,COG1653@2|Bacteria,1TS6D@1239|Firmicutes,248CI@186801|Clostridia,27JZY@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K17318 1.0 ko02010,map02010 1.0 M00603 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.29,3.A.1.1.9 1.0 - 1.0 - 1.0 SBP_bac_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308609 0 0 0 0 343770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 799965 0 0 0 0 820508 0 0 0 0 802588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340090 0 0 0 0 294168 0 0 0 0 261039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 412762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 123634 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CQSTNDAYPTGFR MGYG000002535_03845;MGYG000002507_03184;MGYG000002494_02672;MGYG000002323_03828;MGYG000002506_03862;MGYG000002515_04056 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,3XP1Y@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Aspartate ammonia-lyase 1.0 aspA 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319 1.0 4.3.1.1 1.0 ko:K01744 1.0 ko00250,ko01100,map00250,map01100 1.0 - 1.0 R00490 1.0 RC00316,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_2250,iECs_1301.ECs5120,iG2583_1286.G2583_4966,iSBO_1134.SBO_4317,iSDY_1059.SDY_4444,iSF_1195.SF4293,iSFxv_1172.SFxv_4682,iSSON_1240.SSON_4322,iS_1188.S4560,iUTI89_1310.UTI89_C4736,iYL1228.KPN_04529,iZ_1308.Z5744,ic_1306.c5222 1.0 FumaraseC_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate ammonia-lyase. fumaric aminase. - L-aspartate = fumarate + NH4(+). 1.0 1.0 1.0 1.0 Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 570889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 510921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 668784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 773931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CQVVEGGGEILPSEK MGYG000004797_01913;MGYG000002478_03723;MGYG000000243_00371 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,2FN44@200643|Bacteroidia,4AKAD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway 1.0 nqrF 1.0 - 1.0 1.6.5.8 1.0 ko:K00351 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_6,Fer2,NAD_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 830935 0 0 0 0 0 0 0 0 0 0 830886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 923790 0 0 0 0 0 0 0 0 0 0 746525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644497 0 0 0 0 0 0 0 0 0 0 1005787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243114 0 0 0 0 0 0 0 0 0 0 506195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488013 0 0 0 0 0 0 0 0 0 0 977359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CRDLTDDEVK MGYG000003702_00674;MGYG000001315_01362;MGYG000004271_00041;MGYG000000271_01086;MGYG000000312_01473 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia 0.8 186801|Clostridia 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 - 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CRDLTDDEVKK MGYG000001315_01362 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 - 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321332 0 0 0 0 213686 0 0 456253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522889 0 0 0 0 547959 0 0 481603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87393 0 0 0 0 112191 0 0 396811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498096 0 0 0 0 485926 0 0 318861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437640 0 0 0 0 257657 -(Pyro-carbamidomethyl)CRDLTDDEVKR MGYG000004271_00041;MGYG000000271_01086 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 - 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CRPDEVAYAHAHNVPVPEGANDNPYSIDDNLWGR MGYG000002775_00228;MGYG000003266_01591 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CV0T@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Belongs to the argininosuccinate synthase family. Type 1 subfamily 1.0 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Fluid shear stress and atherosclerosis;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 883507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CSANTDKEGK MGYG000000412_00523;MGYG000000236_04489;MGYG000001319_00792;MGYG000003937_01472;MGYG000000084_02464;MGYG000001302.1_01989 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia 0.3333333333333333 186801|Clostridia 0.5 H 0.8333333333333334 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 0.6666666666666666 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 583195 0 0 0 0 334290 0 0 0 0 379400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 556487 0 0 0 0 287853 0 0 0 0 948503 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CSDQASMHIR MGYG000002517_00142 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0037@1|root,COG0037@2|Bacteria,1V1S0@1239|Firmicutes,24BSC@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 tRNA processing 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1191837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CSFEVAAYDQGAR MGYG000002494_02793;MGYG000002323_03719;MGYG000002534_04280;MGYG000002515_04199 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria 0.75 1236|Gammaproteobacteria 1.0 E 1.0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline 1.0 argI 1.0 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.1.3.3,2.1.3.9 1.0 ko:K00611,ko:K09065 1.0 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 1.0 M00029,M00844,M00845 1.0 R01398,R07245 1.0 RC00096 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECS88_1305.ECS88_4841 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ornithine carbamoyltransferase. | N-acetylornithine carbamoyltransferase. OTCase. | N-acetylornithine transcarbamylase. The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively. | Differs from EC 2.1.3.3.-!-This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic pathway of several eubacteria and has no catalytic activity with L-ornithine as substrate. carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate. | carbamoyl phosphate + N(2)-acetyl-L-ornithine = H(+) + N(2)-acetyl-L- citrulline + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1054537 0 0 0 0 0 0 535066 0 0 0 0 0 0 0 0 1041424 0 841847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CSHEMDWVR MGYG000000196_05082;MGYG000000196_01061 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,4AP35@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tat pathway signal sequence domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 1660301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1978287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1193702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CSIIEVM(Oxidation)GR MGYG000001714_01207;MGYG000004140_01431;MGYG000000263_02969;MGYG000000389_01497;MGYG000002445_01890;MGYG000002670_01194;MGYG000001748_00489;MGYG000000164_01314;MGYG000000193_01502;MGYG000002131_01267;MGYG000000262_01672;MGYG000004271_01479;MGYG000001338_03108;MGYG000000200_01715;MGYG000004785_01977;MGYG000000404_01769;MGYG000002298_02985;MGYG000000252_03136;MGYG000000489_01140;MGYG000000251_02553;MGYG000000087_01570;MGYG000001688_01941;MGYG000002945_02739;MGYG000004799_00788;MGYG000001619_00145;MGYG000004879_03089;MGYG000002517_00722;MGYG000000233_02644;MGYG000002145_01062;MGYG000001374_02297;MGYG000001637_01748;MGYG000004869_03739;MGYG000004519_00079;MGYG000000133_02661;MGYG000003074_00958;MGYG000000205_01904;MGYG000000271_01933;MGYG000002985_01092;MGYG000000118_00086;MGYG000000255_02050;MGYG000001315_03537;MGYG000000201_02247;MGYG000002312_00043;MGYG000000002_03264;MGYG000003486_02032;MGYG000000806_01094;MGYG000000378_01139;MGYG000003012_00904;MGYG000000187_00684;MGYG000002992_01459;MGYG000000152_00728;MGYG000000038_01820;MGYG000000142_02989;MGYG000002492_00955;MGYG000000216_01646;MGYG000000909_01001;MGYG000004589_01118;MGYG000001199_00400;MGYG000000202_02060;MGYG000003694_02580;MGYG000000301_01958;MGYG000000281_00124;MGYG000002279_02763;MGYG000002393_02419;MGYG000001319_01087 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3XYH6@572511|Blautia 0.3076923076923077 186801|Clostridia 1.0 F 0.5230769230769231 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CSIIEVMGR MGYG000001714_01207;MGYG000004140_01431;MGYG000000263_02969;MGYG000000389_01497;MGYG000002445_01890;MGYG000002670_01194;MGYG000001748_00489;MGYG000000164_01314;MGYG000000193_01502;MGYG000002131_01267;MGYG000000262_01672;MGYG000004271_01479;MGYG000001338_03108;MGYG000000200_01715;MGYG000004785_01977;MGYG000000404_01769;MGYG000002298_02985;MGYG000000252_03136;MGYG000000489_01140;MGYG000000251_02553;MGYG000000087_01570;MGYG000001688_01941;MGYG000002945_02739;MGYG000004799_00788;MGYG000001619_00145;MGYG000004879_03089;MGYG000002517_00722;MGYG000000233_02644;MGYG000002145_01062;MGYG000001374_02297;MGYG000001637_01748;MGYG000004869_03739;MGYG000004519_00079;MGYG000000133_02661;MGYG000003074_00958;MGYG000000205_01904;MGYG000000271_01933;MGYG000002985_01092;MGYG000000118_00086;MGYG000000255_02050;MGYG000001315_03537;MGYG000000201_02247;MGYG000002312_00043;MGYG000000002_03264;MGYG000003486_02032;MGYG000000806_01094;MGYG000000378_01139;MGYG000003012_00904;MGYG000000187_00684;MGYG000002992_01459;MGYG000000152_00728;MGYG000000038_01820;MGYG000000142_02989;MGYG000002492_00955;MGYG000000216_01646;MGYG000000909_01001;MGYG000004589_01118;MGYG000001199_00400;MGYG000000202_02060;MGYG000003694_02580;MGYG000000301_01958;MGYG000000281_00124;MGYG000002279_02763;MGYG000002393_02419;MGYG000001319_01087 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3XYH6@572511|Blautia 0.3076923076923077 186801|Clostridia 1.0 F 0.5230769230769231 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 537874 660030 638133 475946 848722 573139 436771 910032 569389 849915 777753 939178 628967 418933 709332 452707 539477 591585 638883 720729 693965 932136 841540 450320 860788 597535 730930 966680 735734 747848 484669 701477 503783 614896 702159 611652 549840 435790 349406 587004 322631 501556 565878 115800 573804 550381 255959 421969 440535 388110 484002 315215 386954 292118 181060 1361552 415270 454943 335521 292514 955512 501353 406630 418700 560457 1263211 656345 360555 616477 457827 317329 478425 482016 404982 300394 356589 745757 824792 725646 522755 364291 471465 504431 692699 484908 687718 541610 796822 677714 698912 765888 644468 692621 478409 740051 677281 682566 641119 637764 502276 841958 892519 711982 850164 588228 690536 593107 891040 1006764 863028 867651 435719 635542 779568 760749 605372 441127 920237 580928 367818 468807 883031 927279 672045 519193 603331 475456 1032773 964805 594726 633207 272525 656722 670613 635376 312361 126896 180525 620111 716696 796770 459518 571614 858878 671988 586902 482963 573108 1082165 769548 872034 542671 994357 1142858 1137673 549744 519494 832505 967474 766121 638469 1110763 945136 903522 495561 1219999 1024859 740523 935750 255933 734603 415324 816068 797345 350981 648953 990778 859857 871152 451069 624070 420825 813968 789056 1230469 525748 687221 815755 642435 590874 -(Pyro-carbamidomethyl)CSIVEVMGR MGYG000000650_00890;MGYG000000989_02475;MGYG000000028_00264;MGYG000002528_01287;MGYG000000179_04958;MGYG000000080_02619 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,2682U@186813|unclassified Clostridiales 0.8333333333333334 186801|Clostridia 1.0 G 0.8333333333333334 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106682 0 80174 0 0 0 0 142919 0 0 0 0 0 0 0 0 0 0 412254 0 0 0 135138 0 0 0 0 0 0 0 0 0 81157 57418 0 0 61112 0 105451 0 374880 0 0 0 0 0 0 0 83448 0 0 0 0 96284 0 373622 666266 0 0 0 413236 0 0 249099 284296 0 0 0 0 345644 319050 300459 0 0 265194 0 919383 0 447524 0 311275 0 0 667566 0 0 976972 0 420463 0 0 310801 0 137768 252119 0 0 0 87940 0 0 131225 131322 0 0 0 0 246208 177690 0 0 0 203167 0 95301 0 0 0 0 0 0 483707 0 0 205066 0 91855 0 0 0 0 353257 0 0 0 0 0 0 0 341998 326193 0 0 0 0 395678 121919 361314 0 0 286805 0 303851 0 0 0 362029 0 0 762178 0 0 0 0 295951 0 0 322830 0 -(Pyro-carbamidomethyl)CSNNYGPYHFPEK MGYG000001661_01673;MGYG000002994_00738;MGYG000003922_00043;MGYG000004558_01494;MGYG000001599_00610;MGYG000004748_00803;MGYG000000029_00536;MGYG000002549_04302;MGYG000000105_02489;MGYG000000255_02670;MGYG000000696_01314;MGYG000000146_01522;MGYG000002992_01118;MGYG000000236_00855;MGYG000002506_03458;MGYG000004762_00029;MGYG000000174_02161;MGYG000000077_01037;MGYG000003701_00934;MGYG000004839_00803;MGYG000000187_00408;MGYG000004317_01742;MGYG000000205_01470;MGYG000001750_00039;MGYG000002950.1_00427;MGYG000000193_02344;MGYG000000013_01636;MGYG000001310_02226;MGYG000001543_01411;MGYG000003681_00071;MGYG000002291_02998;MGYG000000142_02711;MGYG000004479_00899;MGYG000003312_01661;MGYG000000054_02319;MGYG000001378_04346;MGYG000002033_00278;MGYG000001400_02608;MGYG000004561_00703;MGYG000003695_00289;MGYG000000216_01929;MGYG000001783_01061;MGYG000002279_00355;MGYG000000200_01470;MGYG000004604_01556;MGYG000000249_00466;MGYG000002312_00890;MGYG000001313_03263;MGYG000001617_02017;MGYG000004797_03148;MGYG000002952_00715;MGYG000001306_03162;MGYG000002560_02224;MGYG000004185_00765;MGYG000003351_01794;MGYG000002528_00617;MGYG000000781_02576;MGYG000000179_01049;MGYG000003165_01329;MGYG000000044_03155;MGYG000000206_00137;MGYG000001141_01051;MGYG000000018_00879;MGYG000002156_00398;MGYG000003581_01363;MGYG000000251_00915;MGYG000002171_02673;MGYG000001623_02871;MGYG000002281_03831;MGYG000001345_03507;MGYG000002478_00328;MGYG000003367_00501;MGYG000001787_01258;MGYG000002098_00381;MGYG000000273_01234;MGYG000000243_02180;MGYG000000028_01398;MGYG000000356_02067;MGYG000001461_03061;MGYG000001364_01620;MGYG000000107_05121;MGYG000001697_00958;MGYG000000262_02262;MGYG000004899_01501;MGYG000003374_01808;MGYG000002756_03331;MGYG000000222_03512;MGYG000004876_01367;MGYG000000078_00616;MGYG000001338_01660;MGYG000001346_00923;MGYG000002788_01238;MGYG000000562_00802;MGYG000002717_00859;MGYG000004757_01843;MGYG000000038_02127;MGYG000000233_00880;MGYG000000184_00391 domain d__Bacteria 1.0 COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,2FMUH@200643|Bacteroidia,4AME0@815|Bacteroidaceae 0.3979591836734694 976|Bacteroidetes 0.4897959183673469 M 0.9897959183673469 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily 0.9285714285714286 rfbB 0.9795918367346939 - 0.9897959183673469 4.2.1.46 0.9693877551020408 ko:K01710 0.9693877551020408 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 0.9693877551020408 M00793 0.9693877551020408 R06513 0.9693877551020408 RC00402 0.9693877551020408 ko00000,ko00001,ko00002,ko01000 0.9693877551020408 - 1.0 - 1.0 - 0.9897959183673469 GDP_Man_Dehyd 0.9897959183673469 - 1.0 - 1.0 - 1.0 GT2 0.8571428571428571 dTDP-glucose 4,6-dehydratase. - - dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. 0.9693877551020408 0.9693877551020408 0.9693877551020408 0.9693877551020408 Acarbose and validamycin biosynthesis;Biosynthesis of vancomycin group antibiotics;Polyketide sugar unit biosynthesis;Streptomycin biosynthesis 0.9693877551020408 none 1.0 884512 744582 1019513 0 979627 988510 0 1437399 0 0 1079239 0 1101004 824159 1216425 1139948 0 866205 1176866 1079147 0 886786 703931 799935 0 1033022 892849 863280 0 0 0 921491 809805 830317 0 0 773209 744026 834637 935730 872531 0 1187491 635282 0 974375 0 0 1103049 0 1036105 763111 452216 751655 0 1468279 849234 856652 0 608142 822766 767548 0 940889 915840 1151880 0 0 0 1000104 884733 905987 0 0 612697 932502 1038556 2016644 1164577 0 764504 928692 0 1319982 0 0 804012 0 997367 1052664 1221585 1070919 0 707510 1244457 1271214 0 1564577 863645 856895 0 1189499 1240847 825479 0 0 0 959342 1333179 1351962 0 0 1318176 1084113 718131 902857 415847 0 1016244 491671 0 634016 0 0 737845 0 776940 723297 725090 783783 0 355299 605423 881426 0 421396 645651 381442 0 571953 677056 533687 0 0 0 779172 703367 414044 0 0 442113 374779 625067 555807 512658 0 616275 601465 0 800285 0 0 501144 0 689563 711615 331045 714229 0 761507 707259 536126 0 649373 840580 550614 0 815842 312106 826011 0 0 0 517940 851947 963798 0 0 840156 871857 -(Pyro-carbamidomethyl)CSPFRVPLAR MGYG000000236_00181;MGYG000002298_01806;MGYG000004482_00393;MGYG000002079_00687;MGYG000001415_02125;MGYG000002727_00240;MGYG000004760_00878;MGYG000002560_01450;MGYG000001688_03814;MGYG000001698_00702;MGYG000000378_00784;MGYG000004891_00190;MGYG000001313_01473;MGYG000002208_00666;MGYG000001374_00487;MGYG000001577_00663;MGYG000002517_01243;MGYG000000074_01177;MGYG000002963_02777;MGYG000002720_01364;MGYG000001714_01953;MGYG000002139_00077;MGYG000002933_01184;MGYG000001665_01593;MGYG000003801_01123;MGYG000000187_00493;MGYG000003236_01337;MGYG000000371_01679;MGYG000000262_01988;MGYG000003366_01811;MGYG000000044_00817;MGYG000001641_02069;MGYG000000233_02503;MGYG000004869_04101;MGYG000003468_00865;MGYG000000111_01891;MGYG000001789_01569;MGYG000004797_01193;MGYG000001871_00692;MGYG000002040_00906;MGYG000004296_00104;MGYG000002133_02142;MGYG000000312_02404;MGYG000000356_00934;MGYG000001496_03326;MGYG000001562_02560;MGYG000002293_00252;MGYG000003312_03561;MGYG000002105_00879;MGYG000004763_00142;MGYG000002965_00229;MGYG000004221_00458;MGYG000004667_00970;MGYG000001687_00537;MGYG000003374_01797;MGYG000003921_00033;MGYG000002670_01671;MGYG000002590_00564;MGYG000002057_00345;MGYG000000728_00587;MGYG000002274_02693;MGYG000001136_01739;MGYG000000359_00714;MGYG000001345_02795;MGYG000000212_00440;MGYG000002794_01254;MGYG000004733_01907;MGYG000002580_00394;MGYG000004642_01131;MGYG000000170_00404;MGYG000000076_02377;MGYG000000184_00575;MGYG000000281_03419;MGYG000002702_00763;MGYG000000223_02468;MGYG000003899_02226;MGYG000002102_01725;MGYG000001707_02428;MGYG000002922_00885;MGYG000000255_02207;MGYG000000345_00443;MGYG000002212_01829;MGYG000002194_01689;MGYG000002912_00804;MGYG000000198_00250;MGYG000002278_00689;MGYG000002945_01502;MGYG000000133_02955;MGYG000002279_01986;MGYG000000251_01169;MGYG000001748_00979;MGYG000003166_00833;MGYG000000377_01737;MGYG000000636_01370;MGYG000002966_02744;MGYG000000989_01009;MGYG000003952_01418;MGYG000001637_01169;MGYG000000087_02439;MGYG000004713_00347;MGYG000000013_03892;MGYG000001597_00394;MGYG000001615_00145;MGYG000002098_00511;MGYG000001780_04079;MGYG000002926_01683;MGYG000002247_01703;MGYG000003681_00659;MGYG000003542_01534;MGYG000000205_02701;MGYG000001315_01921;MGYG000001300_02837;MGYG000000003_01500;MGYG000000743_01457;MGYG000000352_00288;MGYG000004732_02304;MGYG000004475_00310;MGYG000001328_00836;MGYG000002549_01561;MGYG000003702_00366;MGYG000002552_02286;MGYG000001346_03147;MGYG000003697_00469;MGYG000000404_01435;MGYG000004784_01123;MGYG000002492_01692;MGYG000003486_02360;MGYG000004743_00400;MGYG000002218_01508;MGYG000000489_00801;MGYG000003446_00860;MGYG000000915_00888;MGYG000000142_02834;MGYG000003891_00830;MGYG000000222_00273;MGYG000000171_00241;MGYG000004487_00114;MGYG000000280_02154;MGYG000003819_01577;MGYG000000325_02351;MGYG000000245_03386;MGYG000004087_01282;MGYG000000258_01879;MGYG000000036_01410;MGYG000000179_00100;MGYG000003074_00103;MGYG000003311_01206;MGYG000001787_02320;MGYG000000098_03346;MGYG000002934_01311;MGYG000001647_00185;MGYG000001738_01167;MGYG000003279_00708;MGYG000000196_02017;MGYG000000022_02788;MGYG000003450_00463;MGYG000004810_00381;MGYG000001754_01214;MGYG000001338_02151;MGYG000001646_00500;MGYG000001666_00300;MGYG000003202_01304;MGYG000001310_01399;MGYG000003694_01656;MGYG000001378_01176;MGYG000000077_02459;MGYG000002528_02478;MGYG000000701_00789;MGYG000002523_01400;MGYG000000140_01464;MGYG000002143_00035;MGYG000000392_01615;MGYG000000243_00277;MGYG000004271_01396;MGYG000001786_00858;MGYG000002393_00923;MGYG000002905_00879;MGYG000004517_00262;MGYG000000383_01314;MGYG000001733_00637;MGYG000004526_01655;MGYG000000193_00368;MGYG000003363_02147;MGYG000004879_02866;MGYG000000271_00388;MGYG000002159_01291;MGYG000000417_00539;MGYG000000031_02405;MGYG000000215_00031;MGYG000002478_03849;MGYG000000249_01089;MGYG000002753_00264;MGYG000003307_01519;MGYG000003469_00516;MGYG000002953_01784;MGYG000002438_03578;MGYG000004658_00597;MGYG000002007_01910;MGYG000001661_00974;MGYG000000673_01172;MGYG000000164_00358;MGYG000003381_00006;MGYG000001255_00900;MGYG000001651_00429;MGYG000002126_00460 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.24390243902439024 186801|Clostridia 0.7170731707317073 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8536585365853658 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9853658536585366 - 1.0 - 1.0 - 1.0 GT1 0.9902439024390244 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 3772286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4502144 0 0 0 0 0 0 0 0 0 0 3311115 0 977118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025307 0 0 0 0 0 0 0 0 0 0 792025 0 5070249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5851816 0 0 0 0 0 0 0 0 0 0 5181028 0 1762998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2389396 0 0 0 0 0 0 0 0 0 0 2689452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CSYGWAKED MGYG000002059_01430;MGYG000001564_01809;MGYG000000077_01442;MGYG000001493_05223;MGYG000000179_02171;MGYG000000262_02304;MGYG000000084_01195 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 0.42857142857142855 186801|Clostridia 1.0 F 0.7142857142857143 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 385854 0 104479 274866 0 0 0 0 0 0 0 0 0 0 797108 0 0 0 0 0 0 0 0 0 0 423610 0 0 371095 0 0 0 0 0 0 414984 392628 0 279538 0 0 0 0 0 0 0 0 0 0 0 0 0 143478 0 0 0 0 0 0 0 0 0 0 200076 0 0 345270 0 0 0 0 0 0 268296 262851 0 1045876 0 237504 563391 0 0 0 0 0 0 0 0 0 0 1029331 0 320706 0 0 0 0 0 0 0 0 945288 0 0 692617 0 0 0 235501 0 0 713355 567218 179836 656780 0 460895 553754 0 0 0 0 0 0 0 0 0 0 490210 0 867993 0 0 0 0 0 0 0 0 168991 0 0 770251 0 0 0 589498 0 0 516168 554199 671067 1594364 0 1111050 1378762 0 0 0 0 0 0 0 0 0 0 1731368 0 1175732 0 0 0 0 0 0 0 0 1631919 0 0 2092368 0 0 0 1180726 0 0 1553178 1368990 822947 -(Pyro-carbamidomethyl)CTDAVLAAIDEEKK MGYG000002834_00307;MGYG000002960_02297;MGYG000003697_02228;MGYG000002293_02268;MGYG000001056_01406 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,2FM2W@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 glucosamine-6-phosphate deaminase 1.0 nagB 1.0 - 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso,PIG-L,Sulfatase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 136176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1492088 0 0 0 644187 2636578 0 0 0 0 1894472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CTEEHQAIVR MGYG000002535_00457;MGYG000002494_04238 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3171@1|root,COG3171@2|Bacteria,1RH3U@1224|Proteobacteria,1S6UT@1236|Gammaproteobacteria,3XPPI@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Protein with unknown function (DUF469) 1.0 yggL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 - 1.0 ko:K09923 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF469 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1360817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1465879 0 1171449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CTEYGC(Carbamidomethyl)VNLK MGYG000001300_00298;MGYG000002274_00041 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,3WGGE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acetyl-CoA hydrolase/transferase C-terminal domain 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 936431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CTLTEEQIKTEAK MGYG000002517_01855 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 'glutamate synthase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4,Fer4_20,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 881973 0 0 0 0 0 0 0 0 0 0 0 0 1024252 992083 0 0 0 0 817932 0 0 0 0 892633 793612 0 0 0 0 0 0 0 0 0 0 923474 0 490413 0 0 0 0 0 0 0 0 0 0 0 0 679869 874889 0 0 0 0 386247 0 0 0 0 675488 661597 0 0 0 0 0 0 0 0 0 0 1004668 0 -(Pyro-carbamidomethyl)CTNFGMEKK MGYG000001056_01523;MGYG000004797_02703;MGYG000002549_02753;MGYG000001346_02848;MGYG000001378_02162;MGYG000002478_01618;MGYG000000182_00097;MGYG000003363_00431;MGYG000002293_00175;MGYG000002960_01099;MGYG000001313_02628;MGYG000000243_00156;MGYG000003697_00501;MGYG000002478_03534;MGYG000001345_00471;MGYG000002834_00254;MGYG000002171_02203;MGYG000004876_02773;MGYG000004797_03640 domain d__Bacteria 1.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FM4G@200643|Bacteroidia,4AMFG@815|Bacteroidaceae 0.5263157894736842 976|Bacteroidetes 0.9473684210526315 I 1.0 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 0.5263157894736842 mmdA 0.8421052631578947 - 1.0 - 0.8421052631578947 - 0.8421052631578947 - 0.8421052631578947 - 0.8421052631578947 - 0.8421052631578947 - 0.8421052631578947 - 0.8421052631578947 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 GH101 1.0 - - - - 0.8421052631578947 0.8421052631578947 0.8421052631578947 0.8421052631578947 0.8421052631578947 none 1.0 1534540 1672873 2254647 1740013 2220418 1678112 0 1515480 0 0 1751611 1459839 1906695 2283933 0 2226980 1724567 967166 0 0 0 1372646 904781 2136831 0 1559306 1873233 905183 1941383 0 2193137 2152367 2270023 0 1894994 0 1867507 2711647 1975236 1102052 1745176 1506384 1635570 1426023 0 1693537 0 0 1728836 1620028 1672728 1667983 0 1684831 1582347 524932 0 0 0 1744498 898337 1087509 0 1819582 1920740 695845 1505008 0 935959 1416422 1601537 0 1968543 0 1820631 1461283 1568597 1442856 2272450 1735183 2101618 1778971 0 1691846 0 0 1741909 1487434 1708108 1647791 0 1463201 1148734 2150866 0 0 0 1246356 1675793 1798279 0 1399749 1669321 1898442 1649970 0 1826575 1528360 1436353 0 1679524 0 1869219 1788973 1072950 827611 1705419 1105033 1329717 1357951 0 1341522 0 0 1498299 1307096 1445650 1006805 0 1295038 974643 1191530 0 0 0 1265903 1426008 1238995 0 1333345 1341122 964273 1056543 0 1003292 1295486 1427182 0 1658428 0 1333495 1167015 1157679 824033 1064553 1383050 1980136 1801011 0 1451388 0 0 1513283 1503885 1718496 924068 0 1568451 1220697 1443476 0 0 0 1428568 1215630 1236042 0 1704040 1170987 1073958 1478812 0 1296337 1285286 755570 0 1909383 0 1676694 1550326 -(Pyro-carbamidomethyl)CTNFGQEKK MGYG000004769_00266;MGYG000000236_00438;MGYG000001337_03643 domain d__Bacteria 1.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FM4G@200643|Bacteroidia,4AMFG@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 0.6666666666666666 I 1.0 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 0.6666666666666666 mmdA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 GH101 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1652402 0 0 0 0 1873997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1843897 0 1651385 0 1469976 0 0 0 0 0 0 0 0 0 0 1472747 0 1156451 0 0 0 0 1408663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1197790 0 1176266 0 865484 0 0 0 0 0 0 0 0 0 0 891136 0 1258385 0 0 0 0 1799821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1861975 0 1638475 0 1340856 0 0 0 0 0 0 0 0 0 0 956561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CTQELLFGK MGYG000002323_01542;MGYG000002506_00254;MGYG000002494_01389;MGYG000000093_01888 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,3XNR8@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 L-aspartate:2-oxoglutarate aminotransferase activity 1.0 aspC 1.0 GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.0 2.6.1.1,2.6.1.57 1.0 ko:K00813,ko:K00832 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 M00024,M00025,M00034,M00040 1.0 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 iPC815.YPO1410,iSFxv_1172.SFxv_1000 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. | aromatic-amino-acid transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. | L-methionine can also act as donor, more slowly.-!-Oxaloacetate can act as acceptor.-!-Controlled proteolysis converts the enzyme to EC 2.6.1.1. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. | 2-oxoglutarate + an aromatic L-alpha-amino acid = an aromatic oxo-acid + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 165424 378253 0 0 0 0 0 0 0 0 0 0 0 0 0 136305 0 99261 0 0 0 0 0 0 0 0 0 0 0 0 0 200763 0 0 0 0 253970 0 254447 358762 0 0 0 0 0 0 0 0 0 0 0 0 0 493281 0 475983 0 0 0 0 0 0 0 0 0 0 0 0 0 309291 0 0 0 0 113051 0 86862 115241 0 0 0 0 0 0 0 0 0 0 0 0 0 83010 0 90807 0 0 0 0 0 0 0 0 0 0 0 0 0 66914 0 0 0 0 77681 0 73877 76229 0 0 0 0 0 0 0 0 0 0 0 0 0 138608 0 211346 0 0 0 0 0 0 0 0 0 0 0 0 0 169776 0 0 0 0 330656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CTSAHLGQAFTK MGYG000002438_00431;MGYG000000138_02261 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,2FNWR@200643|Bacteroidia,22XN3@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Xylose isomerase-like TIM barrel 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1164435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4283939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2484584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2739107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6904101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CTTNC(Carbamidomethyl)LAPIAK MGYG000004658_00366;MGYG000004757_00364;MGYG000000196_00479;MGYG000001562_00044;MGYG000000044_01948;MGYG000001643_00773;MGYG000001661_02632;MGYG000004464_00783;MGYG000004734_01400;MGYG000002478_03999;MGYG000001783_01519;MGYG000003697_01698;MGYG000001337_01464;MGYG000001789_00244;MGYG000002293_01263;MGYG000000243_01331;MGYG000004779_01244;MGYG000002506_01169;MGYG000003469_01436;MGYG000004756_01346;MGYG000000170_00182;MGYG000003202_00946;MGYG000001345_01069 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.43478260869565216 976|Bacteroidetes 0.8695652173913043 C 0.5217391304347826 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 0.9565217391304348 - 0.9565217391304348 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9565217391304348 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1627514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1906697 0 0 0 0 609219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CTTNC(Carbamidomethyl)LAPLAK MGYG000002999_00356;MGYG000004468_00660;MGYG000002540_02142;MGYG000000375_01483;MGYG000004734_01400;MGYG000001783_01519;MGYG000003697_01698;MGYG000002057_00658;MGYG000000074_00883;MGYG000004006_01717;MGYG000000354_00611;MGYG000002834_00628;MGYG000004756_01346;MGYG000002007_00386;MGYG000001692_02867;MGYG000002944_01470;MGYG000001345_01069;MGYG000002438_00285;MGYG000003110_00098;MGYG000001562_00044;MGYG000004464_00783;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000000111_00274;MGYG000004536_01441;MGYG000003372_00674;MGYG000000243_01331;MGYG000001448_01713;MGYG000004779_01244;MGYG000002506_01169;MGYG000000273_02725;MGYG000002275_01823;MGYG000003469_01436;MGYG000000099_02094;MGYG000001334_01647;MGYG000003643_00817;MGYG000004658_00366;MGYG000000044_01948;MGYG000001749_01249;MGYG000004487_00117;MGYG000004794_00985;MGYG000001546_00360;MGYG000003542_01626;MGYG000000423_01499;MGYG000001608_00559;MGYG000000412_01371;MGYG000001489_03093;MGYG000000377_02142;MGYG000004638_00838;MGYG000000445_00706;MGYG000001302.1_00095;MGYG000002556_00846;MGYG000003202_00946;MGYG000004411_00321;MGYG000002095_00148;MGYG000003681_00790;MGYG000000003_00712;MGYG000000097_00328;MGYG000002933_02039;MGYG000004482_00387;MGYG000000196_00479;MGYG000004757_00364;MGYG000001643_00773;MGYG000001661_02632;MGYG000003819_01468;MGYG000002549_00455;MGYG000000467_01930;MGYG000001337_01464;MGYG000002737_00455;MGYG000001789_00244;MGYG000002293_01263;MGYG000003155_00741;MGYG000000053_01377;MGYG000000170_00182;MGYG000004831_00204;MGYG000000673_01725;MGYG000002905_02083 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.28205128205128205 976|Bacteroidetes 0.6410256410256411 G 0.6153846153846154 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8717948717948718 gap 0.9743589743589743 - 0.9102564102564102 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9743589743589743 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1090321 0 2254211 0 0 0 0 0 0 1289554 0 1591293 0 0 0 0 0 1245801 0 0 0 0 1215054 0 1468061 1586574 0 0 1402342 0 0 1712898 2184081 0 0 0 1515797 2119698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 149063 0 0 0 294273 0 0 0 0 0 0 152328 0 170654 0 0 0 0 0 694158 0 0 0 0 174527 0 246405 267503 0 545012 322798 0 0 259492 450381 0 0 0 415924 392588 1701300 0 2571998 0 0 0 0 0 0 1548231 0 2260557 0 0 0 0 0 2612788 0 0 0 0 1247982 0 2206999 2128330 0 1639746 1733360 0 0 2777060 2480211 0 0 0 1906531 1066028 0 0 170159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467634 0 0 0 0 468152 0 0 0 0 755584 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CTVEDYDYTKGQGFK MGYG000003697_01174 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0436@1|root,COG0436@2|Bacteria,4NFV4@976|Bacteroidetes,2FN4K@200643|Bacteroidia,4AMHU@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1553556 0 0 0 0 2731429 0 0 0 0 1486140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CTVNDFEYTAGK MGYG000002438_00501 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,2324H@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422854 0 0 0 0 239269 0 0 0 0 388828 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CTYFAVIDK MGYG000004797_02947;MGYG000001337_01561;MGYG000000243_00135;MGYG000002171_02490;MGYG000002478_02940;MGYG000000196_00570;MGYG000001378_02415 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 118868 0 0 0 0 121420 0 0 0 0 188081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139321 0 0 0 0 121433 0 0 0 0 130312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157597 0 0 0 0 132494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232932 0 0 0 0 140685 0 0 0 0 146991 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVATHALNIFGDHSDVYAC(Carbamidomethyl)R MGYG000001637_01998;MGYG000003656_01278;MGYG000000233_01543;MGYG000000255_00343;MGYG000000404_01294;MGYG000000489_00545 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 519955 1701609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 984194 1339651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215969 382134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264522 182470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVC(Carbamidomethyl)TPDKK MGYG000000271_00468 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVDGITANAEHTK MGYG000002447_01881;MGYG000002447_01092 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Mesosutterella|s__Mesosutterella multiformis|m__MGYG000002447 1.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2W02M@28216|Betaproteobacteria,4PQCS@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 E 1.0 Fumarase C C-terminus 1.0 aspA 1.0 - 1.0 4.3.1.1 1.0 ko:K01744 1.0 ko00250,ko01100,map00250,map01100 1.0 - 1.0 R00490 1.0 RC00316,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FumaraseC_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate ammonia-lyase. fumaric aminase. - L-aspartate = fumarate + NH4(+). 1.0 1.0 1.0 1.0 Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1260676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVDMNDR MGYG000000031_02020;MGYG000003869_00786;MGYG000000118_02883;MGYG000000184_03010;MGYG000000212_02552;MGYG000000249_01748;MGYG000000133_00802;MGYG000000142_02498;MGYG000002036_00603;MGYG000001698_00102;MGYG000001356_01588;MGYG000001338_00681;MGYG000003355_04197;MGYG000000171_00584;MGYG000004762_01392;MGYG000002229_00638;MGYG000003628_00321;MGYG000001652_00547;MGYG000000268_00090;MGYG000002854_00387;MGYG000004628_02036;MGYG000002953_02673;MGYG000000142_00761;MGYG000001496_02657;MGYG000001683_01572;MGYG000001698_02021;MGYG000000212_01928;MGYG000004565_00983;MGYG000003468_00280;MGYG000002563_01362;MGYG000002836_01567;MGYG000004781_01910;MGYG000000140_00392;MGYG000004733_02867;MGYG000000466_00763;MGYG000003582_01115;MGYG000004285_01532;MGYG000000031_00146;MGYG000000739_00465;MGYG000003558_01066;MGYG000001777_01705;MGYG000004736_00479;MGYG000000301_00718;MGYG000001606_01069;MGYG000000002_02249;MGYG000001954_00253;MGYG000001493_00835;MGYG000004697_00027;MGYG000003589_00277;MGYG000000743_01174;MGYG000002835_00653;MGYG000000002_01091;MGYG000002279_01909;MGYG000001689_00148;MGYG000000146_00652;MGYG000000171_02356;MGYG000004735_00336;MGYG000004799_00369;MGYG000000119_00545;MGYG000000164_00746;MGYG000002057_01219;MGYG000001647_00733;MGYG000000099_00457;MGYG000002042_01022;MGYG000001651_01713;MGYG000002992_01647;MGYG000000127_02971;MGYG000002998_01059;MGYG000000251_02727;MGYG000001460_03056 domain d__Bacteria 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae 0.38571428571428573 186801|Clostridia 0.9857142857142858 H 0.7285714285714285 Belongs to the formate--tetrahydrofolate ligase family 0.6428571428571429 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 366298 379158 0 0 383629 0 345193 0 304795 804172 308425 0 0 866241 336263 278682 0 278102 0 591803 935168 0 185326 0 369607 314170 0 0 0 0 361971 321849 0 0 0 228463 591726 272519 577638 0 227800 0 93090 300056 130475 0 205794 518731 161569 0 0 253103 97603 135300 0 285542 0 117713 0 0 0 0 131307 365953 0 0 0 553014 0 154129 0 0 0 132285 258601 593612 657923 417160 443215 0 193975 375152 837506 0 780934 506883 607106 0 0 708237 746320 787969 0 656099 0 564526 1058192 0 666426 0 771621 690698 0 0 0 505899 960937 1001557 0 0 0 431807 545911 194165 811234 484928 0 0 0 157988 0 0 212428 344708 472416 0 0 169494 264208 322498 0 0 0 0 163854 0 0 0 0 0 0 0 0 630259 588394 677964 0 0 0 0 557122 1320242 1970046 2171063 1976880 0 1353789 1586039 1163253 0 1467362 569207 1466423 0 0 1321519 1020341 1118626 0 1083298 0 1202094 963782 0 432021 0 526538 990130 0 0 0 1392835 1664312 2061606 0 0 0 315399 1145186 -(Pyro-carbamidomethyl)CVDVAIVEAC(Carbamidomethyl)K MGYG000004769_01827 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,4H31P@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 succinate CoA transferase 1.0 scpC 1.0 - 1.0 2.8.3.18 1.0 ko:K18118 1.0 ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011 1.0 R10343 1.0 RC00012,RC00014 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinyl-CoA:acetate CoA-transferase. SCACT. In some bacteria the enzyme catalyzes the conversion of acetate to acetyl-CoA as part of a modified tricarboxylic acid (TCA) cycle.-!-In other organisms it converts acetyl-CoA to acetate during fermentation.-!-In some organisms the enzyme also catalyzes the activity of EC 2.8.3.27. acetate + succinyl-CoA = acetyl-CoA + succinate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660713 652881 0 780241 499560 0 694371 0 0 837661 0 0 0 0 0 0 0 0 0 0 480232 0 478594 0 0 0 0 645431 0 0 0 550450 0 0 0 0 511891 0 521582 412833 0 176038 441674 0 319023 0 0 495950 0 0 0 0 0 0 0 0 0 0 372182 0 257874 0 0 0 0 378956 0 0 0 307568 0 0 0 0 198038 0 148780 0 0 0 0 0 0 0 0 189191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300531 0 0 0 0 209729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVENAYFIK MGYG000004893_02071;MGYG000003372_04160;MGYG000002689_01090;MGYG000002513_00431;MGYG000002535_03654;MGYG000000179_02516;MGYG000002574_02872;MGYG000001464_02324;MGYG000000242_02080;MGYG000004828_01853;MGYG000002494_02836;MGYG000000152_02649 domain d__Bacteria 1.0 COG3033@1|root,COG3033@2|Bacteria,1NG5U@1224|Proteobacteria,1RS6E@1236|Gammaproteobacteria,3WWJR@544|Citrobacter 0.3333333333333333 186801|Clostridia 0.5833333333333334 E 0.75 Beta-eliminating lyase 0.75 tpl 0.75 - 1.0 4.1.99.2 0.75 ko:K01668 0.75 ko00350,map00350 0.75 - 1.0 R00728 0.75 RC00355,RC00364 0.75 ko00000,ko00001,ko01000 0.75 - 1.0 - 1.0 - 1.0 Beta_elim_lyase 0.75 - 1.0 - 1.0 - 1.0 - 1.0 tyrosine phenol-lyase. beta-tyrosinase. The enzyme cleaves a carbon-carbon bond, releasing phenol and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-The enzyme also slowly catalyzes similar reactions with D-tyrosine, S-methyl-L-cysteine, L-cysteine, L-serine and D-serine. H2O + L-tyrosine = NH4(+) + phenol + pyruvate. 0.75 0.75 0.75 0.75 Tyrosine metabolism 0.75 none 1.0 0 0 116499 0 0 167630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239741 0 110639 0 0 0 0 0 0 0 0 225622 0 0 0 0 150979 0 0 315522 0 0 529982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492171 0 552141 0 0 0 0 0 0 0 0 406564 0 0 0 0 488797 0 0 323603 0 0 342029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453847 0 428218 0 0 0 0 0 0 0 0 514418 0 0 0 0 334317 0 0 310862 0 0 193910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117490 0 101087 0 0 0 0 0 0 0 0 118883 0 0 0 0 195336 0 0 79738 0 0 430849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 482422 0 475719 0 0 0 0 0 0 0 0 722513 0 0 0 0 627607 -(Pyro-carbamidomethyl)CVFTFKR MGYG000000243_01003 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,2FN07@200643|Bacteroidia,4AK76@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 Transcriptional regulatory protein 1.0 yebC 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Transcrip_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 374887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 414787 0 0 0 0 381428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95427 -(Pyro-carbamidomethyl)CVGAALR MGYG000002506_02717 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3XNX9@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 K 1.0 transcriptional regulator 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 280644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435602 0 365357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 195051 0 97632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVGFELR MGYG000002494_04127 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3WV6W@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 K 1.0 Transcriptional regulator PadR-like family 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613176 0 0 0 524810 0 0 0 0 0 0 0 0 0 0 0 614217 0 101336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVHAMNK MGYG000002528_01429 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DAO,FAD_binding_2,FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1069953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVHAMNKK MGYG000002528_01429;MGYG000000028_00487 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DAO,FAD_binding_2,FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 125644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2959451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1831692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVIVEVNENMPR MGYG000002528_02671 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Acetyl-CoA hydrolase transferase 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 411985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 790339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1406887 0 0 0 0 0 0 1153026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVLQDGLHIR MGYG000000262_00350;MGYG000000077_01494 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,25UXF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Aldehyde dehydrogenase (NAD) family protein 1.0 pduP 1.0 - 1.0 1.2.1.87 1.0 ko:K13922 1.0 ko00640,map00640 1.0 - 1.0 R09097 1.0 RC00004,RC00184 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 propanal dehydrogenase (CoA-propanoylating). - The enzyme forms a bifunctional complex with EC 4.1.3.43, with a tight channel connecting the two subunits.-!-Also acts, more slowly, on glycolaldehyde and butanal.-!-In Pseudomonas species the enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.10.-!-NADP(+) can replace NAD(+) with a much slower rate. CoA + NAD(+) + propanal = H(+) + NADH + propanoyl-CoA. 1.0 1.0 1.0 1.0 Propanoate metabolism 1.0 none 1.0 791737 1347975 0 329929 0 898508 201543 959163 0 0 0 1119567 1573580 574954 943804 1421536 1001471 0 685913 995476 0 1460552 0 246179 1117637 659016 546844 0 733139 827967 596202 1240556 0 600425 549001 510233 386331 0 1640611 1547271 0 1313393 0 1336109 3584102 1155259 0 0 0 677500 902696 758126 1210023 607698 750998 0 1408727 2429809 0 897546 0 2498407 1391862 1365723 1400571 0 2907310 1261663 1531833 718059 0 1795163 1425047 1841114 1292373 0 3068797 5218710 0 4373107 0 3164294 950070 3273679 0 0 0 2377366 3036601 2070655 4148610 2917737 2453224 0 3674501 3714749 0 5087224 0 2003452 3513365 3071803 4257990 0 1026000 2458965 1518519 4112380 0 3799401 4606768 1133906 2941784 0 1278796 1808557 0 1545936 0 2546355 2013065 1395100 0 0 0 1083749 1907366 1399890 1176293 2942626 1846711 0 987783 1834063 0 2518746 0 2541061 1208025 711073 0 0 1790336 1480332 1557947 1365563 0 1134363 1221049 1005862 836043 0 2396953 3637712 0 2679215 0 2316627 1946567 2224337 0 0 0 2099673 3243831 2252723 2940998 3812985 2670412 0 3430360 2973016 0 2750747 0 2156883 2919795 2493038 2854633 0 1154756 3217757 4640122 3833477 0 3647273 2423992 2194973 3574642 0 -(Pyro-carbamidomethyl)CVMSDSLC(Carbamidomethyl)IR MGYG000000133_00166;MGYG000003355_02940;MGYG000000301_01358 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,3XZI5@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Aldehyde dehydrogenase family 1.0 eutE 1.0 - 1.0 1.2.1.10,1.2.1.87 1.0 ko:K00132,ko:K13922 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00228,R01172,R09097 1.0 RC00004,RC00184,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetaldehyde dehydrogenase (acetylating). | propanal dehydrogenase (CoA-propanoylating). aldehyde dehydrogenase (acylating). Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme forms a bifunctional complex with EC 4.1.3.43, with a tight channel connecting the two subunits.-!-Also acts, more slowly, on glycolaldehyde and butanal.-!-In Pseudomonas species the enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.10.-!-NADP(+) can replace NAD(+) with a much slower rate. acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NAD(+) + propanal = H(+) + NADH + propanoyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVNDAATMIK MGYG000002670_01511;MGYG000000489_01023;MGYG000002492_00657 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 194795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135293 239390 766308 180321 1125200 259699 0 144744 301826 379709 689680 191386 647055 302834 265281 426417 214122 4151618 104168 489365 0 0 2080288 285862 317020 490067 473084 3247430 125324 190852 400329 0 792473 432370 270636 456286 242812 905172 803323 511412 3613286 861760 988433 589734 0 950750 712886 1012893 1738268 1314548 1578472 981254 1008110 1920500 866672 767748 684034 725436 0 746534 1255671 725607 1040923 1036040 1039791 1694557 780854 766986 1176340 0 4032728 871540 1076722 537624 862502 3925522 0 0 0 0 0 0 0 0 0 0 0 325012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268433 93827 0 0 122568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105094 0 149693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVQMLHDR MGYG000000084_01999 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger formicilis|m__MGYG000000084 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435760 0 0 0 0 454563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 753745 0 0 0 0 772933 0 0 0 0 943165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 512219 0 0 0 0 334424 0 0 0 0 696934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242678 0 0 0 0 467830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133863 0 0 0 0 1239555 0 0 0 0 1462098 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVSHDDDATK MGYG000000262_00532 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,25XEF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10439,ko:K17202 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212,M00590 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 222324 0 0 0 0 0 0 0 0 0 0 0 0 0 309001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 972338 0 0 0 0 0 0 0 0 0 0 0 0 0 742327 0 0 0 0 0 0 0 0 0 0 813339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170240 0 0 0 0 0 0 0 0 0 0 0 0 0 346539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CVVNAAGVYADVFHNMVSSK MGYG000002517_00257 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77892645 0 0 0 -(Pyro-carbamidomethyl)CWAAVKDLATK MGYG000000196_01785 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,4AMYK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CWNDEFQSR MGYG000001300_02598;MGYG000002641_02082;MGYG000002934_02602;MGYG000001627_01176;MGYG000002272_02331;MGYG000003166_00861;MGYG000002545_01196;MGYG000003891_02475;MGYG000002274_01203 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae 0.8888888888888888 186801|Clostridia 0.8888888888888888 G 1.0 ABC-type sugar transport system periplasmic component 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 462455 0 0 0 0 151190 0 0 0 0 212043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1484379 0 0 0 0 1729671 0 0 0 0 1983169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CYAIEEVADQK MGYG000000053_01519;MGYG000000074_02434;MGYG000002007_00972;MGYG000000003_01115;MGYG000001562_02119;MGYG000004006_00750;MGYG000002082_01949 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,22VAD@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 1.0 mce 1.0 - 1.0 5.1.99.1 1.0 ko:K05606 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R02765,R09979 1.0 RC00780,RC02739 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glyoxalase_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA epimerase. methylmalonyl coenzyme A racemase. - (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 133323 0 0 0 252280 0 186527 0 0 336404 0 0 0 0 0 0 0 0 298542 0 262153 0 0 0 0 0 0 0 0 0 0 0 0 216364 0 0 399188 0 223761 0 0 0 259919 0 181084 0 0 338212 0 0 0 0 371434 0 0 0 0 0 296504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298559 0 0 0 0 0 0 0 0 0 0 198576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277697 0 840750 0 0 1071732 1289844 1251382 0 0 0 1013337 0 955987 0 0 773453 0 0 0 0 1795436 0 977028 0 987123 0 1130651 0 0 0 0 0 0 0 0 0 0 1052139 0 -(Pyro-carbamidomethyl)CYAIEEVADQKVR MGYG000000074_02434;MGYG000002082_01949 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,22VAD@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 1.0 mce 1.0 - 1.0 5.1.99.1 1.0 ko:K05606 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R02765,R09979 1.0 RC00780,RC02739 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glyoxalase_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA epimerase. methylmalonyl coenzyme A racemase. - (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 437846 0 0 573652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416237 0 0 0 505001 0 0 0 648297 0 0 647413 0 0 0 377591 0 0 0 396451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1330409 0 0 0 0 0 0 0 0 0 0 459635 0 0 0 346183 0 333263 0 698109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481023 0 0 0 0 0 0 500533 0 0 0 0 0 0 0 1075555 0 0 1729327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1483178 0 0 0 0 0 0 2175874 1318872 -(Pyro-carbamidomethyl)CYDAANAAAEEKVEAVR MGYG000000243_01121 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 748581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518120 0 0 0 0 760133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381459 0 0 0 0 0 -(Pyro-carbamidomethyl)CYDAANAAAEEKVEAVRK MGYG000000243_01121 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 1361531 0 2625314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1810170 0 0 0 0 0 0 2708484 0 0 0 972190 2958310 790372 0 588986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 905291 0 0 0 0 0 0 582584 0 0 0 1111246 799358 547350 0 779012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682806 0 0 0 485283 546410 603777 0 605351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489947 0 0 0 0 0 0 417347 0 0 0 599879 979728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CYDKELLER MGYG000000133_01552 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 COG NOG14451 non supervised orthologous group 1.0 - 1.0 - 1.0 2.7.4.25 1.0 ko:K00945 1.0 ko00240,ko01100,map00240,map01100 1.0 M00052 1.0 R00158,R00512,R01665 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 (d)CMP kinase. deoxycytidylate kinase. The prokaryotic cytidine monophosphate kinase specifically phosphorylates CMP (or dCMP), using ATP as the preferred phosphoryl donor.-!-Unlike EC 2.7.4.14, a eukaryotic enzyme that phosphorylates UMP and CMP with similar efficiency, the prokaryotic enzyme phosphorylates UMP with very low rates, and this function is catalyzed in prokaryotes by EC 2.7.4.22.-!-The enzyme phosphorylates dCMP nearly as well as it does CMP. (1) ATP + CMP = ADP + CDP. (2) ATP + dCMP = ADP + dCDP. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125280 0 0 0 0 0 0 0 0 258606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 860281 0 800548 956096 0 348231 0 0 0 1476388 0 0 1205301 1248193 0 0 970023 0 0 0 1133703 700977 0 410829 0 688214 0 0 0 0 0 1420658 1765039 0 0 0 820775 591318 -(Pyro-carbamidomethyl)CYDSHKGPVVFR MGYG000002506_03438;MGYG000002323_00012;MGYG000003372_00850;MGYG000002534_04862;MGYG000002515_03619;MGYG000002477_00691;MGYG000002535_04244;MGYG000002494_01536;MGYG000002500_04676 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,3XMH2@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Acts on leucine, isoleucine and valine 1.0 ilvE 1.0 GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 iB21_1397.B21_03597,iECBD_1354.ECBD_4269,iECB_1328.ECB_03648,iECD_1391.ECD_03648,iECO103_1326.ECO103_4394 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways;Cysteine and methionine metabolism;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 195666 0 173001 186812 0 0 0 0 0 0 0 0 0 0 237959 0 0 0 0 240300 0 172812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 760609 1080393 0 671018 741494 0 0 0 637604 0 0 0 0 0 0 1117405 0 0 0 0 784131 0 859967 882597 0 0 0 0 0 0 0 903603 0 0 0 0 846415 0 90603 128063 0 92670 120436 0 0 0 0 0 0 0 0 0 0 75628 0 0 0 0 95884 0 127426 597865 0 0 0 0 0 0 0 97146 0 0 0 0 0 0 336756 184584 0 0 0 0 0 0 162333 0 0 0 0 0 0 194251 0 0 0 0 123017 0 0 0 0 0 0 0 0 0 0 150695 0 0 0 0 179587 0 0 112892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CYGADDVQEGVAIMHHENVGVSITGNSTNPTR MGYG000000245_00061;MGYG000000404_00348;MGYG000002517_01686;MGYG000002492_01963;MGYG000004055_00746 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 0.8 183925|Methanobacteria 0.8 F 0.8 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 0.8 purD 0.8 - 1.0 6.3.4.13 0.8 ko:K01945 0.8 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 0.8 M00048 0.8 R04144 0.8 RC00090,RC00166 0.8 ko00000,ko00001,ko00002,ko01000 0.8 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 0.8 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 0.8 0.8 0.8 0.8 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 0.8 none 1.0 0 0 362522 0 0 0 0 382934 0 0 0 0 0 0 0 0 0 0 0 0 384723 0 0 0 0 0 0 0 0 0 0 0 0 0 413433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204316 0 0 0 0 226879 0 0 610682 0 0 0 0 380196 0 0 0 0 0 0 0 0 0 0 0 0 306805 0 0 0 0 0 0 0 0 0 0 0 999404 0 515109 0 0 831236 0 0 468500 0 0 0 0 1012601 0 0 0 0 0 0 0 0 0 0 0 0 1104903 0 0 0 0 0 0 0 0 0 0 0 255317 0 1746150 0 0 348620 0 0 665084 0 0 0 0 537466 0 0 0 0 0 0 0 0 0 0 0 0 540232 0 0 0 0 0 0 0 0 0 0 0 1066167 0 8556140 0 0 653666 -(Pyro-carbamidomethyl)CYGADDVR MGYG000000013_02686;MGYG000003420_01320;MGYG000001658_01116;MGYG000003521_00824;MGYG000002802_02025;MGYG000000347_00819;MGYG000004824_01069;MGYG000002444_01680;MGYG000000269_00015;MGYG000003570_02445;MGYG000000781_01514;MGYG000001400_01185;MGYG000002582_01129;MGYG000004822_01055;MGYG000003891_01818;MGYG000004561_02010;MGYG000000042_01753;MGYG000000196_00899;MGYG000004763_01967;MGYG000004493_00376;MGYG000004797_02907;MGYG000000479_02090;MGYG000001925_01569;MGYG000001806_00888;MGYG000001346_01121;MGYG000002947_01620;MGYG000003535_01608;MGYG000001871_01775;MGYG000002293_01605;MGYG000004276_01664;MGYG000000043_00846;MGYG000000273_02192;MGYG000004482_01421;MGYG000003221_02162;MGYG000003470_00018;MGYG000003589_01350;MGYG000003922_03053;MGYG000003693_01584;MGYG000002603_00277;MGYG000001415_02505;MGYG000004699_02799;MGYG000002080_00203;MGYG000002275_01873;MGYG000003851_01315;MGYG000002218_00562;MGYG000000036_01924;MGYG000000258_00155;MGYG000001770_01218;MGYG000002834_01893;MGYG000001604_01691;MGYG000002438_03055;MGYG000001697_00682;MGYG000004464_00921;MGYG000001577_02122;MGYG000004729_00222;MGYG000000029_00187;MGYG000001378_03489;MGYG000004185_01308;MGYG000002213_00389;MGYG000000045_01847;MGYG000002281_03938;MGYG000001599_00424;MGYG000003457_01216;MGYG000003819_00577;MGYG000002098_00644;MGYG000000374_01026;MGYG000001237_02019;MGYG000000345_00815;MGYG000000433_01203;MGYG000003446_01092;MGYG000004019_01333;MGYG000000392_01121;MGYG000002478_02896;MGYG000001086_01322;MGYG000000223_01510;MGYG000001785_00655 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.32894736842105265 976|Bacteroidetes 0.5394736842105263 S 1.0 Psort location Cytoplasmic, score 8.96 0.47368421052631576 - 0.8947368421052632 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 367266 339799 0 0 0 0 0 0 0 0 0 303626 0 0 0 0 0 240162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396244 137746 0 0 0 0 0 0 0 0 0 243768 214493 0 0 0 0 270684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553590 144581 0 238120 0 0 0 0 0 0 0 482319 444020 0 0 0 0 188113 0 606564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273285 312464 0 138359 0 0 0 0 0 0 0 389970 308507 0 0 0 0 192302 0 279408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 892589 656535 0 754755 0 0 0 0 0 0 0 833491 589106 0 0 0 0 595916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Pyro-carbamidomethyl)CYGANDVMEGVAIMKK MGYG000001300_02120;MGYG000002274_00309;MGYG000000039_01269;MGYG000002224_01738 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 429911 1098275 472619 953803 814440 0 805017 0 0 1244673 1292296 1722328 613495 1034588 981089 0 2224685 331432 536322 1086848 0 1003958 919556 1182270 1088475 0 0 0 1342910 0 1583086 1892849 0 441138 1045293 1262935 1670319 0 1674426 2565761 900226 2097024 2686353 0 1478594 0 0 2039615 1299147 2110587 2932533 1135749 2513246 0 2477010 2014674 1089370 1371792 0 1588729 2837922 2111284 2007509 0 0 0 1807054 0 1038794 1570536 0 1527776 1522465 1290905 750621 0 567013 0 429001 628713 562109 0 331568 0 0 581944 334200 684256 381291 485491 0 0 943088 0 0 0 0 530006 701713 360097 673873 0 0 0 620119 0 325515 630657 0 436075 335305 468468 1335931 0 1582073 1131467 1321933 1679551 1833154 0 1544371 0 0 1348942 1917122 1627048 1520393 1486860 1523661 0 2623971 1238910 1720924 1442867 0 1315426 1837674 1565990 1461520 0 0 0 1825051 0 1704914 1928693 0 1189593 1526564 861013 0 0 593295 0 0 0 325831 0 0 0 0 0 0 0 0 293285 0 0 551236 0 0 0 0 0 0 0 0 0 0 0 0 0 425722 423122 0 0 511372 535019 -(Pyro-carbamidomethyl)CYNIETVEDQK MGYG000004185_00877;MGYG000001661_01872;MGYG000001346_02849;MGYG000002478_02857;MGYG000000029_01865;MGYG000003922_02460;MGYG000004797_02704;MGYG000000196_04520;MGYG000002549_02752;MGYG000002455_03369;MGYG000001378_02161;MGYG000001337_03642;MGYG000001789_01388;MGYG000000236_00439;MGYG000000243_00157;MGYG000000224_01030;MGYG000001599_01157;MGYG000003681_01115;MGYG000001345_00472;MGYG000002171_02202;MGYG000001313_02629;MGYG000000098_00880;MGYG000004876_02774;MGYG000001306_03183 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,4AQJI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 mce 1.0 - 1.0 5.1.99.1 1.0 ko:K05606 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R02765,R09979 1.0 RC00780,RC02739 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glyoxalase_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA epimerase. methylmalonyl coenzyme A racemase. - (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242244 0 488062 0 0 0 0 0 0 0 0 0 0 780471 0 0 0 0 0 0 0 0 0 0 0 0 0 567074 0 0 0 0 0 0 0 0 0 0 331109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469149 0 0 0 0 0 0 0 0 0 0 0 0 148927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307242 0 -(Pyro-carbamidomethyl)CYNIETVEDQKVK MGYG000002470_02013;MGYG000002478_02857;MGYG000004797_02704;MGYG000002455_03369;MGYG000004876_02774;MGYG000001306_03183 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,4AQJI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 mce 1.0 - 1.0 5.1.99.1 1.0 ko:K05606 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R02765,R09979 1.0 RC00780,RC02739 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glyoxalase_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA epimerase. methylmalonyl coenzyme A racemase. - (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 1107386 0 1080203 0 0 1525760 0 757378 1423476 1230565 0 0 0 1305984 0 2237870 1818339 1518340 0 1514872 0 1373298 1194981 1893216 0 1273125 0 1014775 0 0 0 0 1419877 647104 0 0 1050609 1178590 1048176 0 1498508 0 0 1252171 0 1223502 1251331 990578 0 0 0 1304573 0 1865894 1117271 706464 0 0 0 1630852 1050183 1100292 0 1121561 0 932397 0 0 0 0 1227903 391629 0 0 0 1057903 492146 0 840102 0 0 748530 0 0 798649 708276 0 0 0 589386 0 867480 614639 1095603 0 573044 0 498443 830375 746285 0 462663 0 788243 0 0 0 0 487702 0 0 0 522775 744951 381990 0 0 0 0 427847 0 335564 365711 664582 0 0 0 473248 0 473720 298821 0 0 432094 0 404543 289592 409250 0 470420 0 0 0 0 0 0 334161 375404 0 0 373744 238898 1001135 0 1356666 0 0 1620223 0 979519 1670105 796461 0 0 0 867323 0 982051 1550186 1749334 0 1200418 0 1311032 1644895 1488553 0 1647249 0 1463837 0 0 0 0 1112694 1948015 0 0 1547685 2017287 -(Pyro-carbamidomethyl)CYNIETVEDQKVR MGYG000004185_00877;MGYG000001661_01872;MGYG000001346_02849;MGYG000000029_01865;MGYG000003922_02460;MGYG000000196_04520;MGYG000002549_02752;MGYG000001337_03642;MGYG000001378_02161;MGYG000000236_00439;MGYG000000243_00157;MGYG000000224_01030;MGYG000001599_01157;MGYG000003681_01115;MGYG000001345_00472;MGYG000002171_02202;MGYG000001313_02629;MGYG000000098_00880;MGYG000001370_00016 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,4AQJI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 mce 1.0 - 1.0 5.1.99.1 1.0 ko:K05606 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R02765,R09979 1.0 RC00780,RC02739 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glyoxalase_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA epimerase. methylmalonyl coenzyme A racemase. - (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 1186782 1539080 0 0 1746812 1563453 998182 1912450 1281646 0 1927461 1177427 0 0 0 1788227 2089097 1098204 0 0 0 1194705 1222665 1240026 1121274 1528458 0 1189826 0 490702 1984687 1319249 3339398 1889724 0 1455973 1631081 3035265 1006001 698431 1131390 0 1977902 1072847 962282 1474494 1061334 0 1962916 1755030 0 0 0 1272750 1106373 0 0 0 0 1297017 0 873529 1147636 1364801 1110952 0 0 672997 677355 1422780 1044800 988344 0 809950 865214 1195169 1552687 1068797 1741210 0 1930937 1461021 1610853 1136763 1441292 0 1470087 1679268 0 0 0 1249084 882318 1756132 0 0 0 994553 1499860 1223900 860524 1260607 1152370 1326245 0 1013333 1400963 1098408 1169466 981092 0 1510913 1245642 1276570 999612 841219 846408 0 814576 796738 833059 1065853 1323279 0 861647 914983 0 0 0 1235634 899782 729043 0 0 0 778781 846652 759233 1117631 1649099 1311781 387304 0 1090919 677574 1072564 935568 1724421 0 1241119 1007608 674908 497953 258919 563163 0 518136 995052 509331 436675 753358 0 1177889 628967 0 0 0 299390 568905 0 0 0 0 822141 0 849774 706733 656458 499032 648065 0 673400 561514 592727 525170 602345 0 535601 950350 550565 -(Pyro-carbamidomethyl)CYYFGGGDDGSMR MGYG000000198_04292 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283760 0 0 0 0 0 0 0 0 0 0 0 1547429 0 0 0 0 0 0 0 0 1829612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1489491 0 0 0 0 -(SMA)AALENK MGYG000001630_00344;MGYG000003460_00376;MGYG000003460_01250 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotellamassilia 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,1WD2N@1283313|Alloprevotella 0.6666666666666666 976|Bacteroidetes 1.0 J 0.6666666666666666 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 0.6666666666666666 rpsA 0.6666666666666666 - 1.0 - 0.6666666666666666 ko:K02945 0.6666666666666666 ko03010,map03010 0.6666666666666666 M00178 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 br01610,ko00000,ko00001,ko00002,ko03011 0.6666666666666666 - 1.0 - 1.0 - 1.0 S1 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Ribosome 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3843425 0 0 0 0 0 0 -(SMA)AC(Carbamidomethyl)AAANVLLK MGYG000002506_04111 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3ZJCJ@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 F 1.0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 deoA 1.0 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 1.0 2.4.2.4 1.0 ko:K00758 1.0 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 1.0 - 1.0 R01570,R02484,R08222,R08230 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 1.0 Glycos_trans_3N,Glycos_transf_3,PYNP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thymidine phosphorylase. pyrimidine phosphorylase. In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.-!-Formerly EC 2.4.2.23. phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine. 1.0 1.0 1.0 1.0 Metabolic pathways;Drug metabolism - other enzymes;Bladder cancer;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1027031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 855825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(SMA)APAPQTVPDAVETLKR MGYG000003681_01829 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0584@1|root,COG0584@2|Bacteria,4NHVM@976|Bacteroidetes,2FNEP@200643|Bacteroidia,4AP34@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Glycerophosphoryl diester phosphodiesterase family 1.0 glpQ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GDPD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(SMA)ENLDIAGMMNVLNKK MGYG000000184_01511;MGYG000001338_01460;MGYG000000200_00890 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286091 0 0 0 0 0 0 -(SMA)GISKDVNKGIELAEQLAAALGGGVVGASR MGYG000000022_01320 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2417872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(SMA)IGPHTDVPAGDIGVGAR MGYG000002195_01526 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Anaerovoracaceae|g__Emergencia|s__Emergencia sp900551775|m__MGYG000002195 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WCGW@538999|Clostridiales incertae sedis 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.2,1.4.1.3,1.4.1.4 1.0 ko:K00260,ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase. | glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). | (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Taurine and hypotaurine metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4646720 0 0 0 0 0 0 0 2836864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(SMA)INTVEELC(Carbamidomethyl)NR MGYG000000133_00101 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3XYUC@572511|Blautia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 - 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1516653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2568194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(SMA)LAERVAGNVVENFEDIDKAPEER MGYG000001338_03373 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 821107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2668794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(SMA)LLDEGEAGDNVGLLLR MGYG000004757_00594;MGYG000002930_00867;MGYG000003170_00035;MGYG000002905_00001;MGYG000000053_00908;MGYG000004006_00433;MGYG000002762_01733;MGYG000004848_00666;MGYG000000074_01773;MGYG000003460_01161;MGYG000000215_00564;MGYG000001925_01419;MGYG000001302.1_00073;MGYG000003202_00129;MGYG000000357_02040;MGYG000003992_01709;MGYG000002556_01332;MGYG000004658_01205;MGYG000003446_00658;MGYG000003170_00048;MGYG000002540_03367;MGYG000001763_00317;MGYG000000254_02569;MGYG000000348_00283;MGYG000003279_00951 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.32 976|Bacteroidetes 0.92 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 233631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 570014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(SMA)TILEAVAK MGYG000002494_04513 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,3ZKEI@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 92982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 621538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663168 0 0 0 0 0 0 0 0 0 0 0 0 169886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(SMA)TWINEK MGYG000000146_01791 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea|s__Dorea formicigenerans|m__MGYG000000146 1.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Mannitol dehydrogenase 1.0 - 1.0 - 1.0 1.1.1.58 1.0 ko:K00041 1.0 ko00040,ko01100,map00040,map01100 1.0 M00631 1.0 R02555 1.0 RC00085 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Mannitol_dh,Mannitol_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 tagaturonate reductase. Tagaturonate dehydrogenase. - D-altronate + NAD(+) = H(+) + keto-D-tagaturonate + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14989701 0 0 0 0 14727433 0 0 0 0 11769580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70639965 0 0 0 0 85263100 0 0 0 0 70232764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4939733 0 0 0 0 2991734 0 0 0 0 3107105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 27260151 0 0 0 0 43246479 0 0 0 0 23540343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12105496 0 0 0 0 10859023 0 0 0 0 7880289 0 0 0 0 0 0 0 0 0 0 -(SMA)VELAGYLDSYIPEPER MGYG000002535_04656 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter|s__Citrobacter gillenii|m__MGYG000002535 1.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,3ZITI@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15626670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(SMA)VVLNIPMMSAAMDTVTEHR MGYG000002517_01047 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(SPITC_13C(6))AKQAALAAAVK MGYG000001338_03293 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Radical SAM domain protein 1.0 atsB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,Radical_SAM,SPASM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 908588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2293671 0 0 0 0 0 0 -(Succinyl)AADPAAQFEGLK MGYG000000133_00205 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739547 0 0 0 0 0 0 0 0 1918878 0 0 0 0 0 0 0 0 0 0 -(Succinyl)AEDYLGQEVTEAVITVPAYFSDSQR MGYG000004876_01872;MGYG000000196_01218;MGYG000000243_00100;MGYG000002478_02522 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,4ANVI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Succinyl)GMEAVYTLLNIDR MGYG000001300_00435 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia,3WGYT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 MCRA family 1.0 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Succinyl)KAAIGIPEEELR MGYG000000196_04526;MGYG000002478_01776;MGYG000002905_01187;MGYG000002033_00099;MGYG000000243_02506 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.6 976|Bacteroidetes 1.0 G 0.6 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.6 fba 0.6 - 1.0 4.1.2.13 0.6 ko:K01624 0.6 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6 M00001,M00003,M00165,M00167,M00344,M00345 0.6 R01068,R01070,R01829,R02568 0.6 RC00438,RC00439,RC00603,RC00604 0.6 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6 0.6 0.6 0.6 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.6 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1914145 0 0 2419123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Succinyl)LRGLYEGVLTGK MGYG000002298_00811;MGYG000002528_01412;MGYG000000201_03244;MGYG000000142_02223;MGYG000004839_02530;MGYG000003012_01963;MGYG000000095_00309;MGYG000000164_00589;MGYG000004055_01618;MGYG000002279_01299;MGYG000002042_01497;MGYG000000404_01723;MGYG000002517_02750 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.6153846153846154 186801|Clostridia 0.9230769230769231 C 0.7692307692307693 Belongs to the Glu Leu Phe Val dehydrogenases family 0.7692307692307693 gdhA 0.9230769230769231 - 1.0 1.4.1.3,1.4.1.4 0.8461538461538461 ko:K00261,ko:K00262 0.8461538461538461 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.8461538461538461 M00740 0.9230769230769231 R00243,R00248 0.9230769230769231 RC00006,RC02799 0.9230769230769231 ko00000,ko00001,ko00002,ko01000,ko04147 0.9230769230769231 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.9230769230769231 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.8461538461538461 0.8461538461538461 0.8461538461538461 0.8461538461538461 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.8461538461538461 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Succinyl)NKLDANDPEYLQKR MGYG000000262_02730 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7346893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20545860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 186269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Succinyl)TQNQELLDFTAR MGYG000000098_00811 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides bouchesdurhonensis|m__MGYG000000098 1.0 COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,2FM28@200643|Bacteroidia,4AN5I@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 acd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_dehyd_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 1012583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Succinyl_13C(4))EMSFEQMLEESFK MGYG000002517_01648;MGYG000000271_00477 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,21Z6B@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Ribosome;Metabolic pathways;Biosynthesis of secondary metabolites;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4608124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Succinyl_2H(4))AIGSMGGALSNVPAAELGAVVIK MGYG000002485_00796 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0183@1|root,COG0183@2|Bacteria,378R0@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 I 1.0 Belongs to the thiolase family 1.0 - 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44732004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37087729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Succinyl_2H(4))AYELEGSIEDKLNQIVQK MGYG000001338_00681 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Belongs to the formate--tetrahydrofolate ligase family 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Succinyl_2H(4))NLVDAIYAC(Carbamidomethyl)HDGVLR MGYG000002293_00847 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FM0V@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Xaa-His dipeptidase 1.0 pepD_2 1.0 - 1.0 - 1.0 ko:K01270 1.0 ko00480,ko01100,map00480,map01100 1.0 - 1.0 R00899,R04951 1.0 RC00096,RC00141 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Glutathione metabolism;Metabolic pathways 1.0 none 1.0 0 0 283279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9539589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Sulfo-NHS-LC-LC-Biotin)AMTAFQPDVIIALGGGSAMDAGK MGYG000001619_01035 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA9502|s__UBA9502 sp900540335|m__MGYG000001619 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,2686V@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Sulfo-NHS-LC-LC-Biotin)DGAAQR MGYG000004828_01576;MGYG000002485_02480;MGYG000004893_01506 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5330257 0 0 0 0 6852654 0 0 6536640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7643205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37495 0 0 0 0 0 0 0 0 0 0 0 -(Sulfo-NHS-LC-LC-Biotin)EGGHYGDLYVR MGYG000002478_01405;MGYG000001489_02235;MGYG000004797_04333;MGYG000002203_01195 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKS4@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 655880 0 0 0 0 0 0 0 0 0 228587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1507622 0 0 0 0 1769465 0 0 0 0 1250669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458566 0 0 0 0 1854172 0 0 0 0 260535 0 0 0 0 0 0 0 0 0 0 -(Sulfo-NHS-LC-LC-Biotin)VFGGMTSHAAVVAR MGYG000003891_00830 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Sulfo-NHS-LC-LC-Biotin)YPVATRLSLNGTIIVGR MGYG000002478_01945;MGYG000000243_02673;MGYG000000236_04233;MGYG000002455_02631 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,4NE85@976|Bacteroidetes,2FNPE@200643|Bacteroidia,4AKTC@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 C 1.0 Catalyzes the reversible hydration of fumarate to (S)- malate 1.0 fumB 1.0 - 1.0 4.2.1.2 1.0 ko:K01676 1.0 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00374 1.0 R01082 1.0 RC00443 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fumerase,Fumerase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fumarate hydratase. fumarase. - (S)-malate = fumarate + H2O. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 234425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154685 0 298459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293522 0 196417 0 0 0 0 212762 0 0 716873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 764972 0 150122 0 0 0 0 934090 -(TMAB)DMPFLMPVEDVFTISGR MGYG000002057_01066;MGYG000003819_01356;MGYG000003266_00955;MGYG000004475_00887;MGYG000001086_01249;MGYG000002794_01318;MGYG000002926_00232 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,2N71Q@216572|Oscillospiraceae 0.7142857142857143 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 9967781 0 0 0 14090011 0 0 0 0 0 14573816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14888773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3078057 0 0 0 0 0 5787709 0 0 3658513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4955352 0 0 0 0 0 0 0 0 0 0 14636194 0 0 0 0 0 0 0 0 0 0 14578012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMAB)GEMNFDVVIASPDAMR MGYG000002506_03690;MGYG000002494_02478 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,3WVKV@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 315865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 750578 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMAB)HGYVCDVTDEPAVQAMVATIAK MGYG000000013_04699 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp902362375|m__MGYG000000013 1.0 COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,2FMSH@200643|Bacteroidia,4AKTZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Oxidoreductase, short chain dehydrogenase reductase family protein 1.0 idnO 1.0 - 1.0 1.1.1.69 1.0 ko:K00046 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 gluconate 5-dehydrogenase. 5-ketogluconate reductase. - (1) D-gluconate + NADP(+) = 5-dehydro-D-gluconate + H(+) + NADPH. (2) D-gluconate + NAD(+) = 5-dehydro-D-gluconate + H(+) + NADH. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMAB)SNEALGMVETK MGYG000000198_03138 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,2235C@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 CQ 1.0 BMC domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6550003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2365264 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11787884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7095634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1808437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMAB)TSVEDATVPAWLELDR MGYG000002485_02438 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia,36DJ1@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 S 1.0 Amidohydrolase family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490735 0 0 0 0 532308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMAB)VAEGALSETHSILQR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMT)PAEDIVSKDVFDAAVR MGYG000004797_03291;MGYG000002478_00220 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,4AMRT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 GK 1.0 Psort location Cytoplasmic, score 9.26 1.0 glk 1.0 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Neomycin, kanamycin and gentamicin biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2403438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1078464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMT)TISTNLSAQR MGYG000003363_02129 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900766195|m__MGYG000003363 1.0 COG1629@1|root,COG3188@1|root,COG1629@2|Bacteria,COG3188@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4ANM7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 NPU 1.0 Psort location OuterMembrane, score 9.49 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMT)VDSEALADAVEAGK MGYG000000177_00811 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,249PP@186801|Clostridia,36DQS@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CH 1.0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 ldhA 1.0 - 1.0 1.1.1.28 1.0 ko:K03778 1.0 ko00620,ko01120,map00620,map01120 1.0 - 1.0 R00704 1.0 RC00044 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C,PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 D-lactate dehydrogenase. D-lactic dehydrogenase. - (R)-lactate + NAD(+) = H(+) + NADH + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMT2plex)DEGEAGDNVGLLLR MGYG000004757_00594;MGYG000000254_02569;MGYG000002905_00001;MGYG000004658_01205;MGYG000001302.1_00073;MGYG000003202_00129;MGYG000004006_00433 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.42857142857142855 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMT2plex)DLNAASIEAAMSMIAGTAR MGYG000000099_00105;MGYG000000142_01260 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,2N790@216572|Oscillospiraceae 0.5 186801|Clostridia 1.0 J 1.0 50S ribosomal protein L11 0.5 rplK 1.0 - 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 52581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMT2plex)PVEDVFSITGR MGYG000004757_00594;MGYG000000127_03982;MGYG000000196_03974;MGYG000002905_00001;MGYG000001338_03373;MGYG000002098_00731;MGYG000000142_00171;MGYG000001789_00154;MGYG000000236_01807;MGYG000004763_01689;MGYG000002098_01616;MGYG000000098_02017;MGYG000000164_01096;MGYG000004642_00846;MGYG000003202_00129;MGYG000000919_01815;MGYG000001558_01002;MGYG000001310_01963;MGYG000003185_01053;MGYG000003185_01074;MGYG000001415_02515;MGYG000002438_02321;MGYG000004658_01205;MGYG000000193_02083;MGYG000000243_01988;MGYG000000013_02251;MGYG000001780_03476;MGYG000001562_01075;MGYG000002286_02469;MGYG000000216_02406;MGYG000003279_00951;MGYG000003812_01875 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.21875 976|Bacteroidetes 0.5 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.96875 tuf 1.0 - 0.875 - 1.0 ko:K02358 0.9375 - 0.9375 - 0.9375 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9375 - 0.9375 - 1.0 - 0.90625 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9375 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5234027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 74496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28974496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMT6plex)AGAANIVPNSTGAAK MGYG000001311_02933;MGYG000004087_02290;MGYG000001558_01857;MGYG000001688_03910;MGYG000000278_03657;MGYG000000036_01872;MGYG000000362_01155;MGYG000003001_00320;MGYG000000258_00590;MGYG000000145_03615;MGYG000001606_02632;MGYG000000089_01653;MGYG000000909_00644;MGYG000004691_00618;MGYG000003510_00403;MGYG000003465_00706;MGYG000000179_02084;MGYG000002155_00766;MGYG000000193_03247;MGYG000001707_00061;MGYG000003431_01105;MGYG000000690_01295;MGYG000002683_02093;MGYG000002258_00386;MGYG000001954_02254;MGYG000001619_01736;MGYG000002638_00362;MGYG000000463_00862;MGYG000001065_01088;MGYG000001757_00726;MGYG000002946_02881;MGYG000000150_00838;MGYG000000433_00630;MGYG000003656_01296;MGYG000004810_01402;MGYG000004789_01485;MGYG000000242_02076;MGYG000004815_01345;MGYG000004884_01637;MGYG000001493_05257;MGYG000002052_00078;MGYG000000392_01140;MGYG000000231_00608;MGYG000000836_00852;MGYG000000198_04065 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.4222222222222222 186801|Clostridia 0.9111111111111111 C 0.7333333333333333 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5333333333333333 gap 1.0 - 0.9333333333333333 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMT6plex)DLRELMNIPDNYK MGYG000002492_01710 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 186615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TMT6plex)EGLSPCETGIFLETAHPAK MGYG000002478_02214 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,2FMPH@200643|Bacteroidia,4AKDS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Threonine synthase 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 856632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 812175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1319190 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 842381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3620596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TNBS)NETATASLAILK MGYG000003425_00283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-127|s__CAG-127 sp900766925|m__MGYG000003425 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Threonine synthase 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6425728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(TNBS)PVLTPADIIDAR MGYG000004464_01448 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Barnesiellaceae|g__Barnesiella|s__Barnesiella sp900542255|m__MGYG000004464 1.0 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,2FMGP@200643|Bacteroidia,22W2U@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 ATPase family associated with various cellular activities (AAA) 1.0 moxR 1.0 - 1.0 - 1.0 ko:K03924 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1128297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 966087 0 0 0 0 0 0 0 0 0 0 1249607 0 -(Triton)DFDSIDNAPEEKER MGYG000003542_01415 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900769445|m__MGYG000003542 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Triton)LALFPLSTEGWAEQR MGYG000002478_01404 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 6678575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_210)SYGMLMTDILPARDDQGR MGYG000002478_00647 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKGC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02014 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)AGVTKEDINAAMK MGYG000003694_01737;MGYG000001311_02933;MGYG000001186_01925;MGYG000001065_01088;MGYG000000271_03250;MGYG000004271_00554;MGYG000000404_00344;MGYG000001493_05257;MGYG000002517_01026;MGYG000000179_02084;MGYG000002492_01379;MGYG000000489_00503;MGYG000000198_04065 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6153846153846154 186801|Clostridia 1.0 G 0.6153846153846154 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.6153846153846154 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320634 0 0 324667 0 458690 0 0 0 460221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505441 0 0 0 0 0 0 0 0 0 361218 0 0 0 0 0 0 415180 0 0 0 0 0 0 805347 0 788327 0 0 0 0 341327 0 770716 0 0 0 662305 973477 0 0 0 0 0 0 0 0 0 0 0 270552 0 0 0 0 0 0 0 359718 456950 0 0 377467 0 821118 180454 0 0 272798 0 0 0 0 0 0 397169 0 1674490 0 3118574 0 0 1707082 1464190 0 2338618 3196039 0 1690340 0 0 1891115 0 3340711 0 1971756 1528858 1885366 0 0 1277748 0 889945 2009816 0 0 1437325 1293380 0 2140934 0 0 1528979 1049934 1050945 -(Unknown_216)AVVDAGWKPR MGYG000000080_01477 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 630182 0 0 0 0 0 0 0 0 0 -(Unknown_216)AYTGDQMTLDGPQRK MGYG000003694_01737;MGYG000000038_02185;MGYG000001607_01815;MGYG000001310_02090;MGYG000000249_01352;MGYG000000205_02269;MGYG000000262_01195;MGYG000000140_01181;MGYG000002528_00367;MGYG000000223_00996;MGYG000001711_02099;MGYG000002279_00557;MGYG000001496_01122;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000002966_00075;MGYG000000404_00344;MGYG000003335_00316;MGYG000000233_00345;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000252_01324;MGYG000000077_00219;MGYG000002945_00682;MGYG000000312_01508;MGYG000004610_00503;MGYG000004740_01468;MGYG000002212_00259;MGYG000004296_01958;MGYG000000213_00374;MGYG000002517_01026;MGYG000000142_01979;MGYG000001299_00204;MGYG000004707_01697;MGYG000000251_00555;MGYG000000212_01474;MGYG000002974_01418;MGYG000004785_01017;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001338_02547;MGYG000000133_02283;MGYG000002298_02410;MGYG000001315_01699;MGYG000000153_00303;MGYG000000489_00503 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5490196078431373 186801|Clostridia 0.9215686274509803 C 0.7058823529411765 Psort location Cytoplasmic, score 0.5882352941176471 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284043 0 0 0 0 0 0 0 0 0 0 0 0 468487 0 0 0 0 0 0 0 901041 0 0 0 0 1187179 815051 0 0 0 0 859870 0 0 0 0 1307250 903277 0 0 0 0 0 0 0 0 0 0 752074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)DKPFLMPIEDVFTITGR MGYG000000255_02009 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,27W01@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)FNPDGTLDR MGYG000001637_02230;MGYG000001367_03001;MGYG000001615_04300;MGYG000003074_00586;MGYG000002141_01824;MGYG000000356_02130;MGYG000000489_01026;MGYG000001617_02046;MGYG000000080_01476;MGYG000002278_01894;MGYG000004719_02002;MGYG000000997_00555;MGYG000001777_01059;MGYG000000312_02426;MGYG000002445_02276;MGYG000002528_02668;MGYG000003702_03102;MGYG000004359_01906;MGYG000000028_00944;MGYG000000271_02101;MGYG000000404_01798;MGYG000000398_00614;MGYG000002492_00660;MGYG000000154_01281;MGYG000002517_00543;MGYG000003486_02521;MGYG000001319_02234;MGYG000000217_01341 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.5357142857142857 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.5357142857142857 etfB 1.0 - 0.9642857142857143 - 0.8571428571428571 ko:K03521 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.8571428571428571 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 1.0 none 1.0 0 0 0 0 0 0 0 0 314703 296493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492314 0 0 0 0 0 0 0 0 0 0 763729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 655279 590078 0 0 0 0 0 0 0 0 0 271176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)IFGPVAR MGYG000002560_00246;MGYG000004396_01391;MGYG000000121_02203;MGYG000003921_00353;MGYG000000136_02068;MGYG000003899_00624;MGYG000002965_00668;MGYG000000405_00842;MGYG000002393_00685;MGYG000002418_00868;MGYG000000243_01961;MGYG000003367_01234;MGYG000000133_00055;MGYG000003694_02438;MGYG000004732_00524;MGYG000001835_01798;MGYG000001604_00189;MGYG000003420_00101;MGYG000004769_00449;MGYG000002720_00272;MGYG000004733_00978;MGYG000002291_02245;MGYG000001447_01054;MGYG000002619_02376;MGYG000002670_00396;MGYG000003073_00057;MGYG000000105_02014;MGYG000000301_00170;MGYG000001754_00741;MGYG000004006_01212;MGYG000004158_01541;MGYG000001616_02247;MGYG000002148_03767;MGYG000000159_01021;MGYG000001925_01442;MGYG000000184_01182;MGYG000001615_01739;MGYG000000272_00835;MGYG000003374_01451;MGYG000002835_00986;MGYG000001789_00120;MGYG000000198_04897;MGYG000000074_01952;MGYG000000802_00713;MGYG000002057_00243;MGYG000001338_02797;MGYG000001637_00021;MGYG000003142_01853;MGYG000004763_00936;MGYG000000216_02353;MGYG000004735_01591;MGYG000000696_01653;MGYG000003012_01779;MGYG000002935_01249;MGYG000003375_01792;MGYG000003346_00191;MGYG000000911_00434;MGYG000001367_00359;MGYG000000462_00473;MGYG000003273_00547;MGYG000000414_01234;MGYG000003013_00823;MGYG000001186_01102;MGYG000002963_00444;MGYG000000022_02030;MGYG000000205_02194;MGYG000000144_01704;MGYG000000274_01727;MGYG000000016_01671;MGYG000002250_00105;MGYG000000212_03057;MGYG000003937_00257;MGYG000002156_01360;MGYG000003074_00525;MGYG000000084_01012;MGYG000003266_00870;MGYG000002145_00328;MGYG000002925_00079;MGYG000002944_01730;MGYG000000080_02265;MGYG000003539_00301;MGYG000004019_02165;MGYG000002218_02510;MGYG000001619_00824;MGYG000002065_01089;MGYG000002290_02014;MGYG000004479_01422;MGYG000001627_01322;MGYG000000222_02479;MGYG000002298_00338;MGYG000003355_02352;MGYG000001439_02153;MGYG000002651_00738;MGYG000002834_00450;MGYG000000213_00204;MGYG000002820_00726;MGYG000000002_00872;MGYG000000252_01809;MGYG000000208_01759;MGYG000002545_01130;MGYG000000271_01071;MGYG000001477_00028;MGYG000000263_01425;MGYG000001310_00097;MGYG000001562_01955;MGYG000004475_01148;MGYG000001776_00078;MGYG000000031_02256;MGYG000000145_02799;MGYG000002492_00385;MGYG000001255_02123;MGYG000000179_04590;MGYG000002737_01338;MGYG000000053_00703;MGYG000002716_01485;MGYG000001346_01509;MGYG000004848_00703;MGYG000001975_01106;MGYG000001733_00023;MGYG000003282_01790;MGYG000002485_02421;MGYG000004271_00026;MGYG000001636_00356;MGYG000001502_00402;MGYG000002279_01062;MGYG000002978_01109;MGYG000000195_02123;MGYG000000138_02879;MGYG000000356_00514;MGYG000002082_00477;MGYG000002945_02574;MGYG000002610_01884;MGYG000000095_00564;MGYG000000185_02307;MGYG000002040_00980;MGYG000002989_00867;MGYG000002753_00203;MGYG000003166_00769;MGYG000002517_02863;MGYG000001672_00432;MGYG000000050_01182;MGYG000001444_01646;MGYG000002224_01650;MGYG000002312_02267;MGYG000002272_00461;MGYG000003241_00581;MGYG000002845_00988;MGYG000000233_02353;MGYG000002202_01349;MGYG000004124_01028;MGYG000000042_01081;MGYG000003268_00796;MGYG000001315_01346;MGYG000001056_01159;MGYG000001364_02744;MGYG000000143_00634;MGYG000000039_01695;MGYG000002274_00835;MGYG000004680_02469;MGYG000003519_00370;MGYG000002836_03711;MGYG000000181_01082;MGYG000000781_00858;MGYG000002108_01883;MGYG000003697_01458;MGYG000001464_01860;MGYG000002059_00502;MGYG000001613_01098;MGYG000002438_02218;MGYG000000142_02057;MGYG000003422_00856;MGYG000004833_01895;MGYG000001531_03077;MGYG000000776_00450;MGYG000004828_02406;MGYG000003274_01538;MGYG000000223_03149;MGYG000000273_00396;MGYG000002203_01157;MGYG000000201_02091;MGYG000002154_01340;MGYG000004140_01825;MGYG000004784_00626;MGYG000000224_00466;MGYG000000164_02754;MGYG000002966_02565;MGYG000002115_00719;MGYG000003984_01595;MGYG000004468_00447;MGYG000002775_00023;MGYG000002854_00099;MGYG000003147_00990;MGYG000002641_00978;MGYG000002954_00797;MGYG000002795_00406;MGYG000000806_01293;MGYG000003695_00642;MGYG000001157_01268;MGYG000001970_02200;MGYG000004464_01257;MGYG000001199_01758;MGYG000002794_00549;MGYG000000489_01448;MGYG000002603_01757;MGYG000004569_00147;MGYG000004469_01431;MGYG000004487_01012;MGYG000002777_00379;MGYG000002563_00497;MGYG000002080_00551;MGYG000004716_01212;MGYG000004565_00400;MGYG000002050_01544;MGYG000000054_03868;MGYG000001543_00407;MGYG000002234_01451;MGYG000000215_01904;MGYG000001306_02670 domain d__Bacteria 1.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,36IUH@31979|Clostridiaceae 0.2798165137614679 186801|Clostridia 0.6055045871559633 J 1.0 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome 1.0 rplN 1.0 - 0.7018348623853211 - 1.0 ko:K02874 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L14 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461843 0 0 0 0 0 0 0 0 579546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1142762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1841183 0 0 0 0 0 0 0 0 1293280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)IVGDGIAIKPTGNK MGYG000002507_04262;MGYG000003390_03803;MGYG000002494_03971;MGYG000002506_01939;MGYG000000093_00708;MGYG000002534_03519;MGYG000002504_02873;MGYG000000235_01040;MGYG000003365.1_02703;MGYG000002477_02073;MGYG000002500_03419;MGYG000002535_01116;MGYG000002515_00713;MGYG000002323_02957 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2190@1|root,COG2190@2|Bacteria,1MWIQ@1224|Proteobacteria,1RNE3@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 G 1.0 pts system 1.0 crr 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009892,GO:0009898,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045912,GO:0048519,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071944,GO:0080090,GO:0098552,GO:0098562 1.0 - 1.0 ko:K02777 1.0 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 1.0 M00265,M00266,M00268,M00270,M00272,M00303,M00806 1.0 R02738,R02780,R04111,R04394,R05132,R08559 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.1 1.0 - 1.0 e_coli_core.b2417,iAF1260.b2417,iAPECO1_1312.APECO1_4128,iB21_1397.B21_02278,iBWG_1329.BWG_2179,iE2348C_1286.E2348C_2603,iEC042_1314.EC042_2626,iEC55989_1330.EC55989_2707,iECABU_c1320.ECABU_c27380,iECBD_1354.ECBD_1264,iECB_1328.ECB_02317,iECDH10B_1368.ECDH10B_2582,iECDH1ME8569_1439.ECDH1ME8569_2351,iECD_1391.ECD_02317,iECED1_1282.ECED1_2861,iECH74115_1262.ECH74115_3648,iECIAI1_1343.ECIAI1_2475,iECIAI39_1322.ECIAI39_2563,iECNA114_1301.ECNA114_2494,iECO103_1326.ECO103_2936,iECO111_1330.ECO111_3147,iECO26_1355.ECO26_3470,iECOK1_1307.ECOK1_2734,iECS88_1305.ECS88_2607,iECSE_1348.ECSE_2708,iECSF_1327.ECSF_2281,iECSP_1301.ECSP_3365,iECUMN_1333.ECUMN_2739,iECW_1372.ECW_m2646,iEKO11_1354.EKO11_1311,iETEC_1333.ETEC_2530,iEcDH1_1363.EcDH1_1244,iEcE24377_1341.EcE24377A_2704,iEcHS_1320.EcHS_A2552,iEcSMS35_1347.EcSMS35_2572,iEcolC_1368.EcolC_1261,iG2583_1286.G2583_2949,iJO1366.b2417,iJR904.b2417,iLF82_1304.LF82_0357,iNRG857_1313.NRG857_12120,iSFV_1184.SFV_2469,iSF_1195.SF2472,iSFxv_1172.SFxv_2721,iSSON_1240.SSON_2506,iS_1188.S2618,iUMN146_1321.UM146_04535,iUMNK88_1353.UMNK88_3019,iUTI89_1310.UTI89_C2751,iWFL_1372.ECW_m2646,iY75_1357.Y75_RS12665,ic_1306.c2952 1.0 PTS_EIIA_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Biofilm formation - Vibrio cholerae;Biofilm formation - Escherichia coli;Starch and sucrose metabolism;Phosphotransferase system (PTS);Glycolysis / Gluconeogenesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 771163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 566261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)LVEADNAVDIAHK MGYG000000077_00330 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum soehngenii|m__MGYG000000077 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 529957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 843461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1444966 0 0 0 489516 1865549 0 0 0 0 0 0 0 0 0 0 0 884695 0 0 316579 0 244290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)LVEADNAVDIAHKER MGYG000000077_00330 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum soehngenii|m__MGYG000000077 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 880675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)MTDLDLAGKR MGYG000002506_02523;MGYG000002494_04273;MGYG000002507_00704;MGYG000000093_02472;MGYG000002323_03392 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0126@1|root,KOG1367@2759|Eukaryota,37R6T@33090|Viridiplantae,3GA5G@35493|Streptophyta,4JDX3@91835|fabids 1.0 2759|Eukaryota 1.0 G 1.0 Belongs to the phosphoglycerate kinase family 1.0 - 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N,MS_channel,PGK,TM_helix,Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 625163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 867636 0 0 0 0 -(Unknown_216)MYAGFSTAEESNKR MGYG000004717_00702;MGYG000004769_01826;MGYG000004804_00343;MGYG000000591_01064;MGYG000002659_00371;MGYG000001626_00536;MGYG000001365_01210 class d__Bacteria|p__Firmicutes_C|c__Negativicutes 1.0 COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H22W@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 bhbA 1.0 - 1.0 5.4.99.2 1.0 ko:K01848 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00375,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)NLFIPGKK MGYG000002293_02708;MGYG000003697_02283;MGYG000000272_01790;MGYG000002080_01422;MGYG000001920_01212;MGYG000001789_02670 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 0.6666666666666666 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 196221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82992 0 0 0 0 283225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 123911 0 0 0 0 100527 0 0 759234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356351 0 0 0 0 534625 0 0 145534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408948 0 0 0 0 0 -(Unknown_216)SFDQIDNAPEEKER MGYG000003152_01866;MGYG000002930_00867;MGYG000004588_00463;MGYG000004464_00178;MGYG000002603_01782;MGYG000001630_01142;MGYG000003374_00521;MGYG000003353_00058;MGYG000003424_00456;MGYG000003460_01161;MGYG000000215_00564;MGYG000001925_01419;MGYG000001806_01406;MGYG000002293_00521;MGYG000004763_01689;MGYG000003681_02037;MGYG000002291_02272;MGYG000003202_00129;MGYG000002080_00527;MGYG000001770_01653;MGYG000003992_01709;MGYG000002470_01245;MGYG000001313_00097;MGYG000004629_00424;MGYG000003691_01713;MGYG000001780_03476;MGYG000002540_03367;MGYG000003697_01485;MGYG000002455_03884;MGYG000001763_00317;MGYG000000254_02569;MGYG000003812_01875;MGYG000003497_00215;MGYG000001360_01239;MGYG000003535_00219;MGYG000002834_01866;MGYG000000673_00997 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4P1C5@976|Bacteroidetes,2FX1Q@200643|Bacteroidia 0.3783783783783784 976|Bacteroidetes 0.9459459459459459 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9459459459459459 tuf 1.0 - 0.9459459459459459 - 1.0 ko:K02358 0.9459459459459459 - 0.9459459459459459 - 0.9459459459459459 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9459459459459459 - 0.9459459459459459 - 1.0 - 0.9459459459459459 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9459459459459459 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1872959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)SFDSIDNAPEEKER MGYG000000042_01421;MGYG000004756_01173;MGYG000000196_03974;MGYG000002905_00001;MGYG000000138_00665;MGYG000001661_02666;MGYG000000053_00908;MGYG000004006_00433;MGYG000002762_01733;MGYG000000074_01773;MGYG000001789_00154;MGYG000000273_00431;MGYG000000054_03933;MGYG000000236_01807;MGYG000003701_03123;MGYG000000098_02017;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000001503_00139;MGYG000002281_02290;MGYG000004474_01617;MGYG000003546_00955;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000003446_00658;MGYG000001552_00984;MGYG000001346_01533;MGYG000000243_01988;MGYG000000013_02251;MGYG000001562_01075;MGYG000000348_00283;MGYG000003279_00951;MGYG000000414_00662;MGYG000001655_02933;MGYG000000044_01721;MGYG000002418_00753;MGYG000000117_01463;MGYG000000168_03211 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5810675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1751540 0 0 0 0 0 0 0 345657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2529036 0 1195237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4270017 3656809 974948 5751517 7943761 1945400 0 0 428596 0 4248310 751433 0 2105320 4300512 0 2509424 970780 0 2768394 2134090 2007131 1717727 1605060 0 3561852 1800555 2340075 4062260 2608913 3214250 5607364 0 3407675 2432903 1387527 3703631 0 -(Unknown_216)SSASFGYNEDPIVSSDVIGMR MGYG000003465_00706 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__CAG-272|g__CAG-841|s__CAG-841 sp900544285|m__MGYG000003465 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)TSIFDAK MGYG000004468_00660;MGYG000002540_02142;MGYG000004734_01400;MGYG000001783_01519;MGYG000003457_01802;MGYG000001174_00433;MGYG000000074_00883;MGYG000003423_01365;MGYG000004748_00450;MGYG000002944_01470;MGYG000001345_01069;MGYG000002438_00285;MGYG000002026_00895;MGYG000004464_00783;MGYG000002926_01713;MGYG000004513_03104;MGYG000000254_01186;MGYG000002478_03999;MGYG000004760_00889;MGYG000001313_02393;MGYG000004847_00969;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000002067_00330;MGYG000002281_04045;MGYG000000043_01774;MGYG000004658_00366;MGYG000002084_00526;MGYG000004822_01148;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000004526_01607;MGYG000002455_02200;MGYG000001356_02656;MGYG000004487_00117;MGYG000001608_00559;MGYG000001489_03093;MGYG000004726_03349;MGYG000004638_00838;MGYG000000445_00706;MGYG000001302.1_00095;MGYG000003252_01337;MGYG000002095_00148;MGYG000003202_00946;MGYG000003514_00715;MGYG000003681_00790;MGYG000002933_02039;MGYG000004482_00387;MGYG000000196_00479;MGYG000004285_00359;MGYG000003693_00860;MGYG000001657_02260;MGYG000001661_02632;MGYG000004642_01190;MGYG000002549_00455;MGYG000002737_00455;MGYG000003155_00741;MGYG000000170_00182;MGYG000003908_00471;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.3968253968253968 976|Bacteroidetes 0.6507936507936508 G 0.5079365079365079 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7777777777777778 gap 0.9365079365079365 - 0.9206349206349206 1.2.1.12 0.9841269841269841 ko:K00134 0.9841269841269841 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9841269841269841 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9841269841269841 R01061 0.9841269841269841 RC00149 0.9841269841269841 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9841269841269841 - 1.0 - 1.0 - 0.9523809523809523 Gp_dh_C,Gp_dh_N 0.9841269841269841 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9841269841269841 0.9841269841269841 0.9841269841269841 0.9841269841269841 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9841269841269841 none 1.0 0 0 197619 0 0 0 0 0 156396 0 0 0 0 0 0 0 219527 0 0 217884 0 123513 0 233947 0 0 0 0 0 527442 0 0 0 171195 0 147456 0 233561 0 0 472325 0 0 526115 0 0 463242 0 0 0 0 0 0 0 0 855429 0 373681 0 279120 0 631121 0 0 0 632946 0 0 0 0 291739 772569 0 0 0 1510992 0 0 616012 0 0 423081 0 0 1311142 0 0 248033 0 0 0 0 2600468 1409353 0 288603 332386 452286 3528830 1698650 0 0 0 1536743 0 197984 0 0 0 568287 0 1915731 0 2130831 0 0 404442 0 0 0 0 0 0 0 0 470117 0 0 0 0 0 0 0 159376 0 200241 0 1097272 0 0 0 0 0 475551 0 0 582162 1603846 0 371224 0 189437 0 0 1149676 0 0 1198027 0 0 1625946 0 0 1067212 0 0 0 0 1419281 3485394 0 1371219 1159462 0 2466920 1282929 0 0 0 490272 0 1656917 0 0 439824 634678 0 756984 0 389461 -(Unknown_216)TTLTAAITK MGYG000000080_02058;MGYG000000171_02844;MGYG000004732_02398;MGYG000000303_01575;MGYG000000089_01901;MGYG000001688_04229;MGYG000004718_00646;MGYG000003547_00975;MGYG000000280_01200;MGYG000002259_00929;MGYG000001754_00089;MGYG000004565_01266;MGYG000000198_01165;MGYG000003324_00542;MGYG000003155_00314;MGYG000004804_01395;MGYG000002563_00522;MGYG000003937_01027;MGYG000003411_00716;MGYG000000919_01815;MGYG000001234_01151;MGYG000003992_01709;MGYG000001623_00993;MGYG000002563_00509;MGYG000003895_00135;MGYG000001619_01314;MGYG000000348_00283;MGYG000004296_01668;MGYG000004508_00787;MGYG000000742_00548;MGYG000001809_00576;MGYG000004573_00004;MGYG000001434_01407;MGYG000000258_00266;MGYG000001541_00185;MGYG000001300_00280;MGYG000003851_00676;MGYG000004769_00437;MGYG000002084_01252;MGYG000003869_01538;MGYG000002578_00911;MGYG000001611_00087;MGYG000000371_01541;MGYG000000255_02009;MGYG000002040_01212;MGYG000000404_00531;MGYG000000164_01096;MGYG000000018_00453;MGYG000002794_01318;MGYG000001606_01669;MGYG000004474_01617;MGYG000004804_00945;MGYG000003868_01133;MGYG000001359_01254;MGYG000002224_01123;MGYG000004201_01254;MGYG000000532_02409;MGYG000000036_01380;MGYG000001248_01383;MGYG000002286_02469;MGYG000003073_01160;MGYG000001616_00520;MGYG000002937_00892;MGYG000002052_00232;MGYG000000369_00927;MGYG000001086_01249;MGYG000001365_00649;MGYG000001615_01716;MGYG000002116_00788;MGYG000002854_00111;MGYG000002695_01057;MGYG000000016_02519;MGYG000001756_00183;MGYG000003819_01356;MGYG000004769_00412;MGYG000000395_01440;MGYG000001524_01606;MGYG000000802_00776;MGYG000000271_03365;MGYG000000867_00556;MGYG000002944_02285;MGYG000002993_01302;MGYG000001310_01963;MGYG000002953_03321;MGYG000000022_02283;MGYG000002528_01098;MGYG000004680_02443;MGYG000000090_01714;MGYG000001737_01514;MGYG000002895_00716;MGYG000003428_00555;MGYG000001248_00621;MGYG000003686_02367;MGYG000001784_02227;MGYG000001749_02490;MGYG000002980_01277;MGYG000001779_00600;MGYG000001356_01661;MGYG000004526_00639;MGYG000003166_01350;MGYG000003868_01166;MGYG000003425_03741;MGYG000000251_00064;MGYG000001590_00854;MGYG000000233_00807;MGYG000000142_00171;MGYG000002702_01978;MGYG000001528_00736;MGYG000000182_00585;MGYG000002143_01659;MGYG000000084_02000;MGYG000002126_00299;MGYG000004642_00846;MGYG000001559_00042;MGYG000000187_02029;MGYG000002854_00124;MGYG000001698_04050;MGYG000001443_06656;MGYG000000445_01370;MGYG000002272_01482;MGYG000000249_00026;MGYG000001444_01618;MGYG000002212_00196;MGYG000004799_01385;MGYG000001814_01592;MGYG000003656_01823;MGYG000003486_01055;MGYG000002970_01555;MGYG000003013_00349;MGYG000003484_00308;MGYG000002715_01695;MGYG000002659_00459;MGYG000001732_00030;MGYG000000206_00901;MGYG000004733_01211;MGYG000001389_01588;MGYG000003096_01037;MGYG000002106_00224;MGYG000001673_01975;MGYG000001654_02237;MGYG000002619_00483;MGYG000004735_00884;MGYG000002926_00232;MGYG000002578_00898;MGYG000001760_00949;MGYG000000099_01234;MGYG000000392_00966;MGYG000000133_02991;MGYG000004879_01608;MGYG000001389_00024;MGYG000002707_01740;MGYG000000466_00679;MGYG000001444_01634;MGYG000002994_01317;MGYG000002202_00030;MGYG000003266_00392;MGYG000004482_01535;MGYG000001576_02230;MGYG000000216_02406;MGYG000003628_01000;MGYG000001563_01273;MGYG000000034_01346;MGYG000002685_01157;MGYG000001652_01300;MGYG000002557_00102;MGYG000001338_03373;MGYG000004502_00031;MGYG000000139_00697;MGYG000002762_01733;MGYG000001502_01278;MGYG000003266_00955;MGYG000004826_01022;MGYG000003274_01474;MGYG000001757_01274;MGYG000002234_01026;MGYG000000032_01232;MGYG000001777_01732;MGYG000002105_00002;MGYG000004285_00597;MGYG000000333_00136;MGYG000000262_00030;MGYG000004196_01067;MGYG000002772_01895;MGYG000002057_01066;MGYG000003921_01124;MGYG000001238_02207;MGYG000002996_00986;MGYG000002448_02351;MGYG000004475_00887;MGYG000001319_01764;MGYG000002279_01932;MGYG000000201_03875;MGYG000004547_01366;MGYG000003063_00662;MGYG000001516_01186;MGYG000004717_00227;MGYG000004726_01622;MGYG000004276_00122;MGYG000001925_01419;MGYG000004788_02115;MGYG000001315_01207;MGYG000001602_02247;MGYG000000266_00259;MGYG000003273_00234;MGYG000000140_01590;MGYG000001065_02730;MGYG000002609_01147;MGYG000000263_00836;MGYG000003899_01642;MGYG000003583_01411;MGYG000000179_00920;MGYG000000173_00405;MGYG000000177_01044;MGYG000002290_01325;MGYG000001531_00906;MGYG000003465_01528;MGYG000001141_02439;MGYG000002530_01393;MGYG000000024_03409;MGYG000003872_01017;MGYG000002972_00178;MGYG000001567_01738;MGYG000001439_02427;MGYG000004087_00551;MGYG000000242_00282;MGYG000002417_01244;MGYG000001559_01093;MGYG000002641_00069;MGYG000004558_00415;MGYG000000212_03313;MGYG000002830_01189;MGYG000002837_02416;MGYG000001500_01929;MGYG000000370_00784;MGYG000002006_00835;MGYG000000193_02083;MGYG000000622_01283;MGYG000002720_00092;MGYG000003236_02455;MGYG000004746_00230;MGYG000004630_01824;MGYG000000501_01307;MGYG000000405_00711;MGYG000002848_00884;MGYG000001617_01406;MGYG000003001_00359;MGYG000002596_02296;MGYG000003620_01283;MGYG000001007_01315 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.20080321285140562 186801|Clostridia 0.7469879518072289 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9678714859437751 - 1.0 ko:K02358 0.9919678714859438 - 0.9919678714859438 - 0.9919678714859438 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9919678714859438 - 0.9919678714859438 - 1.0 - 0.9959839357429718 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9919678714859438 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 616757 0 0 0 1498697 0 0 0 1070641 0 0 1022783 0 0 1633232 0 0 0 0 0 0 289005 0 0 0 0 2386742 0 1510092 0 2111448 3711546 702591 0 0 0 2716175 0 1004187 2775147 1665908 3514938 2707232 0 0 0 2431247 0 0 1085011 0 0 1010706 0 0 0 0 0 0 2393428 0 0 0 0 1209597 0 2180595 0 2034599 0 1592070 0 0 0 375624 0 2463110 2716646 1926600 907988 1895151 0 0 0 874951 0 0 1650826 0 0 639372 0 0 0 0 0 0 0 0 0 0 0 1452880 0 0 0 0 1540415 666581 0 0 0 0 0 406121 653903 0 2723515 0 0 0 0 0 -(Unknown_216)VLILTGGPDKK MGYG000002492_00917;MGYG000000280_01601 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.5 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1272897 0 0 0 0 1314779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)VLPELNGK MGYG000000038_02185;MGYG000001311_02933;MGYG000000375_01483;MGYG000003582_01256;MGYG000001558_01857;MGYG000002619_02023;MGYG000003374_01118;MGYG000003821_01266;MGYG000000272_02321;MGYG000002947_01132;MGYG000001400_02195;MGYG000003828_01578;MGYG000000354_00611;MGYG000004681_01193;MGYG000000262_01195;MGYG000001763_00396;MGYG000001707_00061;MGYG000003110_00098;MGYG000000223_00996;MGYG000001711_02099;MGYG000002258_00386;MGYG000004732_01055;MGYG000001255_00370;MGYG000001496_01122;MGYG000004493_00097;MGYG000000002_02120;MGYG000002194_02222;MGYG000004271_00554;MGYG000002966_00075;MGYG000003274_01603;MGYG000002970_00369;MGYG000004317_00142;MGYG000000233_00345;MGYG000001652_01009;MGYG000000231_00608;MGYG000000077_00219;MGYG000000127_04855;MGYG000002993_00787;MGYG000000815_03106;MGYG000001445_01532;MGYG000002945_00682;MGYG000000229_00395;MGYG000004610_00503;MGYG000002098_00013;MGYG000001608_00559;MGYG000002212_00259;MGYG000004826_01307;MGYG000001606_02632;MGYG000000173_00071;MGYG000000213_00374;MGYG000003465_00706;MGYG000002517_01026;MGYG000000003_00712;MGYG000004707_01697;MGYG000002683_02093;MGYG000000212_01474;MGYG000001643_00773;MGYG000002126_00535;MGYG000004642_01190;MGYG000001789_00244;MGYG000000515_01608;MGYG000001338_02547;MGYG000003074_01265;MGYG000001493_05257;MGYG000004396_00612;MGYG000000217_00275;MGYG000002905_02083;MGYG000001439_00571;MGYG000003589_01892;MGYG000000280_02459;MGYG000000188_00829;MGYG000000249_01352;MGYG000003695_01114;MGYG000003423_01365;MGYG000004756_01346;MGYG000004691_00618;MGYG000002641_00563;MGYG000000193_03247;MGYG000000140_01181;MGYG000000080_03115;MGYG000001562_00044;MGYG000002279_00557;MGYG000004799_00704;MGYG000001814_01253;MGYG000002968_00328;MGYG000003656_01296;MGYG000003372_00674;MGYG000000242_02076;MGYG000002492_01379;MGYG000000198_04065;MGYG000001199_01005;MGYG000001749_01249;MGYG000001658_00407;MGYG000001688_03910;MGYG000002972_00451;MGYG000000278_03657;MGYG000000362_01155;MGYG000001319_00348;MGYG000000495_01130;MGYG000001303_01883;MGYG000000258_00590;MGYG000004638_00838;MGYG000002051_00298;MGYG000000187_02264;MGYG000003504_01686;MGYG000000371_00136;MGYG000004519_00423;MGYG000003202_00946;MGYG000000615_00488;MGYG000001423_00991;MGYG000001157_00577;MGYG000000584_01909;MGYG000000171_00850;MGYG000000195_01135;MGYG000001008_00728;MGYG000000271_03250;MGYG000002293_01263;MGYG000000562_01218;MGYG000004622_00259;MGYG000000022_00437;MGYG000000133_02283;MGYG000002298_02410;MGYG000002675_01717;MGYG000000489_00503;MGYG000000399_00360;MGYG000003694_01737;MGYG000002540_02142;MGYG000003831_00170;MGYG000001607_01815;MGYG000000230_01325;MGYG000000484_01691;MGYG000003697_01698;MGYG000002057_00658;MGYG000001710_00672;MGYG000000036_01872;MGYG000003001_00320;MGYG000000205_02269;MGYG000003510_00403;MGYG000000802_01543;MGYG000000690_01295;MGYG000002528_00367;MGYG000004140_01100;MGYG000002478_03999;MGYG000002286_00420;MGYG000000164_00800;MGYG000004847_00969;MGYG000001748_01525;MGYG000002946_02881;MGYG000000150_00838;MGYG000000243_01331;MGYG000002506_01169;MGYG000000404_00344;MGYG000004815_01345;MGYG000001718_00619;MGYG000000141_02825;MGYG000003552_01242;MGYG000003702_00925;MGYG000001781_01334;MGYG000000392_01140;MGYG000002304_00547;MGYG000001356_02656;MGYG000001546_00360;MGYG000002494_01669;MGYG000000045_02136;MGYG000002507_01945;MGYG000000162_00065;MGYG000000089_01653;MGYG000004296_01958;MGYG000002155_00766;MGYG000000179_02084;MGYG000000142_01979;MGYG000000263_01341;MGYG000000806_01930;MGYG000001697_00003;MGYG000001299_00204;MGYG000000251_00555;MGYG000002992_00164;MGYG000002974_01418;MGYG000004285_00359;MGYG000002997_01277;MGYG000003819_01468;MGYG000002025_02240;MGYG000000463_00862;MGYG000002737_00455;MGYG000000433_00630;MGYG000001602_01805;MGYG000004884_01637;MGYG000002052_00078;MGYG000000053_01377;MGYG000001970_02077;MGYG000004246_01300;MGYG000000153_00303;MGYG000003908_00471;MGYG000001315_01699;MGYG000001627_00130;MGYG000002035_01208;MGYG000000941_01985;MGYG000003409_01628;MGYG000003012_02911;MGYG000001310_02090;MGYG000002445_01920;MGYG000000325_00586;MGYG000002834_00628;MGYG000000909_00644;MGYG000002944_01470;MGYG000002775_01122;MGYG000003431_01105;MGYG000003149_01253;MGYG000002026_00895;MGYG000000369_00836;MGYG000003450_00202;MGYG000001954_02254;MGYG000000254_01186;MGYG000002638_00362;MGYG000001415_02219;MGYG000000215_01375;MGYG000001065_01088;MGYG000004810_01402;MGYG000000100_02166;MGYG000002131_02428;MGYG000002067_00330;MGYG000003335_00316;MGYG000000084_01085;MGYG000000836_00852;MGYG000001300_02008;MGYG000004866_01631;MGYG000003937_01177;MGYG000000252_01324;MGYG000000365_00999;MGYG000003363_01174;MGYG000004822_01148;MGYG000000301_01012;MGYG000004722_00591;MGYG000000044_01948;MGYG000001186_01925;MGYG000004087_02290;MGYG000003899_01412;MGYG000000312_01508;MGYG000000204_00778;MGYG000003013_01053;MGYG000002857_01020;MGYG000004288_00401;MGYG000000974_00886;MGYG000004714_00143;MGYG000000281_02732;MGYG000002556_00846;MGYG000001619_01736;MGYG000000398_00286;MGYG000001683_01827;MGYG000001421_02311;MGYG000004789_01485;MGYG000003812_01036;MGYG000004735_01946;MGYG000003503_01071;MGYG000000673_01725;MGYG000000266_00946;MGYG000001567_00998;MGYG000004593_01977;MGYG000000345_01945 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.1583011583011583 186801|Clostridia 0.6718146718146718 C 0.5675675675675675 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5868725868725869 gap 0.9768339768339769 - 0.9305019305019305 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9652509652509652 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 668170 0 842327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 947340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)VLVATDKPFAK MGYG000004763_00834;MGYG000000224_02581;MGYG000000243_00366;MGYG000003681_00721;MGYG000002561_02267;MGYG000003367_00322;MGYG000003363_03157;MGYG000002478_03726;MGYG000001346_03050 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 0.8888888888888888 976|Bacteroidetes 1.0 C 0.8888888888888888 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385764 0 0 0 0 213189 0 0 599399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_216)YAWEEAEHASK MGYG000000170_00133;MGYG000001302.1_00876;MGYG000002007_00952;MGYG000000196_00855;MGYG000002561_03555;MGYG000001461_01112;MGYG000002455_02720;MGYG000001337_03530;MGYG000002203_01956;MGYG000002867_00443;MGYG000004006_00639;MGYG000003467_00199;MGYG000000437_02174;MGYG000000074_02407;MGYG000001546_02758;MGYG000000243_02810;MGYG000000236_00566;MGYG000000003_01138;MGYG000002171_00343;MGYG000001420_01351;MGYG000001920_02116 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1592@1|root,COG1592@2|Bacteria,4NJ7V@976|Bacteroidetes,2FP1G@200643|Bacteroidia,22UC5@171550|Rikenellaceae 0.5714285714285714 976|Bacteroidetes 1.0 C 1.0 Rubrerythrin 0.5714285714285714 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 104326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609879 0 0 0 0 404681 0 0 76782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105267 0 0 0 0 214565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_234)QTKLTTKESELLGLLC(Carbamidomethyl)AHANEILQR MGYG000002478_00018 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia,4AKWQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 1.0 rprY 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Response_reg,Trans_reg_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 46570205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_248)VCGYDDYSLFLINSGAEANENALK MGYG000003363_01506 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900766195|m__MGYG000003363 1.0 COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,2FNR5@200643|Bacteroidia,4AKEG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family 1.0 argD 1.0 - 1.0 2.6.1.11,2.6.1.17 1.0 ko:K00821 1.0 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00028,M00845 1.0 R02283,R04475 1.0 RC00006,RC00062 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetylornithine transaminase. | succinyldiaminopimelate transaminase. succinylornithine aminotransferase. | succinyldiaminopimelate transferase. Also acts on L-ornithine and N(2)-succinyl-L-ornithine. 2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L- glutamate 5-semialdehyde. | 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (S)-2- succinylamino-6-oxoheptanedioate + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Lysine biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1303165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_250)PILGGEATFSFGEAIK MGYG000001338_01563 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 2BJ52@1|root,32DE8@2|Bacteria,1UQYJ@1239|Firmicutes,258RQ@186801|Clostridia,3WMD6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Protein of unknown function (DUF2829) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF2829 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3457102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_302)EELTGPEYARRFINQALDLNIEYR MGYG000002517_00256 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1186787 0 0 0 0 0 0 0 -(Unknown_302)EGGRTVGAGQIIEIIK MGYG000000170_00073 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900240235|m__MGYG000000170 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_420)EAADKATADDIK MGYG000002517_00194;MGYG000000271_03294 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1525049 0 0 0 0 0 0 0 0 0 3086730 0 0 0 0 3430263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2307655 0 0 0 0 0 0 0 0 0 4133612 0 0 0 0 1068862 0 0 0 -(Unknown_420)EEINAAMK MGYG000004828_01576;MGYG000002485_02480 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 274113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1475699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1731484 0 0 -(Unknown_420)EGATAIC(Carbamidomethyl)HGATGK MGYG000003012_02122;MGYG000001311_02316;MGYG000002945_01110;MGYG000000076_00148;MGYG000000271_00682;MGYG000000181_00360;MGYG000004869_02793;MGYG000000177_02080;MGYG000004296_00572;MGYG000003702_01632;MGYG000000245_01511;MGYG000000179_03143;MGYG000004087_00138;MGYG000004642_01769;MGYG000002517_01103;MGYG000000404_01916;MGYG000001374_00302;MGYG000000198_02164 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,21XSH@1506553|Lachnoclostridium 0.2777777777777778 186801|Clostridia 1.0 E 0.7222222222222222 Belongs to the argininosuccinate synthase family. Type 1 subfamily 0.6666666666666666 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Fluid shear stress and atherosclerosis;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179852 0 0 0 0 0 0 0 0 0 448160 274145 0 1126431 0 538502 0 0 898951 0 0 0 1661016 1913329 1082593 0 0 1716584 810628 1402206 0 0 0 0 0 0 1607396 0 565081 2193899 0 0 0 0 0 1004996 0 0 1869853 1922863 1965263 -(Unknown_420)GQVLAKPGTVTC(Carbamidomethyl)HHK MGYG000002492_00344;MGYG000002517_00205 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697547 0 0 0 0 333997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 688586 0 0 0 0 0 0 0 0 2026660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1043749 0 990302 0 0 1784433 0 1484797 -(Unknown_420)IYSESADETKDK MGYG000000179_05046 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4369750 0 733366 0 0 1574352 0 0 1585972 0 2231910 2457369 0 3895145 0 0 6837971 0 0 7107469 2334570 0 0 3973216 3072892 3721635 6588020 0 0 4470065 0 0 2549585 0 0 6066133 6779381 4506243 -(Unknown_420)KATQVYSHEVEK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_420)KVVLTANAQK MGYG000000031_02020;MGYG000000002_02249;MGYG000000142_00761;MGYG000000142_02498;MGYG000001698_00102;MGYG000001338_00681 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae 0.8333333333333334 186801|Clostridia 1.0 H 1.0 Belongs to the formate--tetrahydrofolate ligase family 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1127960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_420)KYVQDTSVTSK MGYG000000089_02197 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4141698 0 0 0 0 534175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_420)MTAAKAEQLIDQGIITDGMIVK MGYG000002494_01894 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,3XM7I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde 1.0 argC 1.0 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.2.1.38 1.0 ko:K00145 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028,M00845 1.0 R03443 1.0 RC00684 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iSSON_1240.SSON_4131 1.0 AA_kinase,Semialdhyde_dh,Semialdhyde_dhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 N-acetyl-gamma-glutamyl-phosphate reductase. NAGSA dehydrogenase. - N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 302455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_420)PEIMLVGATAIGR MGYG000000312_02427;MGYG000000164_00688;MGYG000002492_00661;MGYG000002517_00544;MGYG000000245_02023;MGYG000002528_02669 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8333333333333334 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_420)TDGSHVTSDLGDGKK MGYG000000089_02197 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2718652 0 0 0 0 3175332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Unknown_420)VSQAEADDIKK MGYG000002610_00935;MGYG000002619_00763;MGYG000002651_00254;MGYG000001300_02635;MGYG000002223_01729 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 803889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Xlink_BS2G[113])SKVVLAGAC(Carbamidomethyl)R MGYG000002857_02065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Hydrogeniiclostridium|s__Hydrogeniiclostridium sp900550095|m__MGYG000002857 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,27J2B@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 989666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(Xlink_EGS[226])AVTQALGMIETK MGYG000000359_01134;MGYG000000359_01133 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7182|s__|m__MGYG000000359 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia 1.0 186801|Clostridia 1.0 CQ 1.0 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259914 0 0 0 0 0 0 0 0 0 0 0 0 268090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306932 0 0 0 0 0 0 0 0 0 0 525073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 761700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1577690 0 0 0 0 0 0 0 0 0 0 2126085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(biotinAcrolein298)MESVMK MGYG000002438_02119 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG2133@1|root,COG2133@2|Bacteria,4PMXZ@976|Bacteroidetes,2G0K9@200643|Bacteroidia,2324V@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Domain of Unknown Function (DUF1080) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1080 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314196 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134411 0 0 0 0 0 0 0 0 0 0 6840683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15171939 0 0 0 0 0 0 0 0 0 0 0 0 -(dNIC)ADIIMILINDEK MGYG000000301_00839;MGYG000004735_00452;MGYG000000201_04066;MGYG000004087_02660;MGYG000001496_01234;MGYG000000271_00298;MGYG000002517_01587 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 0.42857142857142855 186801|Clostridia 1.0 EH 0.5714285714285714 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(dNIC)AEILKEEGYIANYK MGYG000004828_02462;MGYG000002485_02425 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0096@1|root,COG0096@2|Bacteria,379ZT@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit 1.0 rpsH 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02994 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 402398 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225817 0 0 0 0 0 0 0 567546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463947 0 0 0 0 408322 0 0 162409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221515 0 0 0 0 140596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524752 -(dNIC)FAPHMALVPMVIEQTSR MGYG000002535_03209;MGYG000002494_00469 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,3WVQ6@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 OU 1.0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins 1.0 clpP 1.0 GO:0000502,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017171,GO:0019538,GO:0019899,GO:0030163,GO:0031597,GO:0032991,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051117,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 1.0 3.4.21.92 1.0 ko:K01358 1.0 ko04112,ko04212,map04112,map04212 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 CLP_protease 1.0 - 1.0 - 1.0 - 1.0 - 1.0 endopeptidase Clp. protease Ti. Belongs to peptidase family S14. Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs). 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 474412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282249 0 415205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1062663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1340656 0 743555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338040 0 260946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(dNIC)INDLCPVDYMAYMLK MGYG000002293_01263;MGYG000003697_01698 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7468347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(dNIC)QLDEAQAGDNIGALLR MGYG000002492_00344;MGYG000002517_00205;MGYG000000245_03248;MGYG000002670_00364 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)AAASESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)ACKVPFQPR MGYG000000039_01677;MGYG000003291_01619;MGYG000002040_00964;MGYG000002272_00439;MGYG000002545_01146;MGYG000002059_01092;MGYG000001157_01746;MGYG000003899_00602;MGYG000000084_00993;MGYG000003166_00747;MGYG000002274_00854;MGYG000001255_02057;MGYG000001300_02903 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Probable zinc-ribbon domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-trcl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2724752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4645587 0 0 0 0 0 0 0 0 -(glycidamide)ADDEANTITVDGK MGYG000000690_01295;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.5 186801|Clostridia 1.0 G 0.5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)AKMPCLVTALSELNQPR MGYG000000997_00555;MGYG000000271_02101 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)ALAATDGDMDKAVEFLR MGYG000001619_02441;MGYG000000233_01317;MGYG000000179_02938;MGYG000000909_00278;MGYG000000274_02582;MGYG000000198_02721;MGYG000000194_00522;MGYG000000278_03744;MGYG000002445_00993 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,21ZJJ@1506553|Lachnoclostridium 0.8888888888888888 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1470524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1591922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)ALLLLK MGYG000001328_01553;MGYG000004536_01045;MGYG000000312_00604;MGYG000002234_01825;MGYG000000205_01544;MGYG000003142_01539;MGYG000000389_00676;MGYG000002517_01844;MGYG000001489_04239;MGYG000000245_00420;MGYG000001423_01504 domain d__Bacteria 1.0 COG1143@1|root,COG4624@1|root,COG1143@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia 0.2727272727272727 186801|Clostridia 0.8181818181818182 C 0.5454545454545454 Iron only hydrogenase large subunit, C-terminal domain 0.2727272727272727 - 0.7272727272727273 - 1.0 1.12.7.2 0.5454545454545454 ko:K00533 0.5454545454545454 - 0.7272727272727273 - 0.7272727272727273 R00019 0.5454545454545454 - 0.7272727272727273 ko00000,ko01000 0.5454545454545454 - 1.0 - 1.0 - 1.0 Fe_hyd_lg_C,Fer4,Fer4_6,Fer4_7 0.5454545454545454 - 1.0 - 1.0 - 1.0 - 1.0 ferredoxin hydrogenase. uptake hydrogenase. Can use molecular hydrogen for the reduction of a variety of substances.-!-Formerly EC 1.12.1.1, EC 1.12.7.1, EC 1.18.3.1, EC 1.18.99.1 and EC 1.98.1.1. H2 + 2 oxidized [2Fe-2S]-[ferredoxin] = 2 H(+) + 2 reduced [2Fe-2S]- [ferredoxin]. 0.5454545454545454 0.5454545454545454 0.5454545454545454 0.5454545454545454 0.7272727272727273 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3165772 0 0 3676994 0 0 0 0 0 3724852 0 0 1425838 0 0 0 0 0 2921146 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)APGDDATYLDYFQK MGYG000002993_01407 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-170|s__CAG-170 sp000432135|m__MGYG000002993 1.0 COG0747@1|root,COG0747@2|Bacteria 1.0 2|Bacteria 1.0 E 1.0 dipeptide transport 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1079473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)APKPVFTDAYFLDK MGYG000004536_01290 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900542505|m__MGYG000004536 1.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,4PKTH@976|Bacteroidetes,2G35Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Conserved carboxylase domain 1.0 - 1.0 - 1.0 4.1.1.3,6.4.1.1 1.0 ko:K01571,ko:K01960 1.0 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 1.0 M00173,M00620 1.0 R00217,R00344 1.0 RC00040,RC00367 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 Biotin_lipoyl,Biotin_lipoyl_2,HMGL-like,OAD_gamma,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | pyruvate carboxylase. | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). pyruvic carboxylase. | oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The animal enzyme requires acetyl-CoA. | The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. ATP + hydrogencarbonate + pyruvate = ADP + H(+) + oxaloacetate + phosphate. | H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)DIYENLHAAGVVDPAK MGYG000001345_00379 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides xylanisolvens|m__MGYG000001345 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 969220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1116479 0 1003398 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3977843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2315485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1763573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)DRPVYC(Carbamidomethyl)SEC(Carbamidomethyl)FAK MGYG000000084_00993;MGYG000003937_01603 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Probable zinc-ribbon domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-trcl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1072046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1205007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1366227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1152540 -(glycidamide)FDNYTFDGSIK MGYG000003279_01059 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900541585|m__MGYG000003279 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1236422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)GENITDLAAK MGYG000000022_01830 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44796621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)GILLGYAR MGYG000002517_01919 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,25CDF@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 M42 glutamyl aminopeptidase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Peptidase_M42 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73687389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)GLCGTDANNLLTSVVER MGYG000001346_03676;MGYG000002281_00884;MGYG000002561_01098;MGYG000002455_04522 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1208@1|root,COG1208@2|Bacteria,4PKJR@976|Bacteroidetes,2G07F@200643|Bacteroidia,4AKG8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 JM 1.0 COG NOG09722 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NTP_transf_3,NTP_transferase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1016449 0 0 0 0 0 1159941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)GNAGAPAVHYLLDSR MGYG000000074_00948 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,2FN8N@200643|Bacteroidia,22UCK@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 CO 1.0 Domain of unknown function (DUF4369) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AhpC-TSA,DUF4369,Thioredoxin_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 67666 0 232232 0 0 161008 0 91998 0 0 0 85927 0 0 0 0 849628 1481105 0 0 0 129337 0 0 0 0 0 0 0 0 88365 0 0 0 0 170450 0 0 190099 0 243118 75866 0 0 0 0 0 0 0 166120 0 0 115293 0 0 0 0 0 0 0 0 0 0 0 0 132961 0 0 0 0 0 0 0 0 0 0 0 0 113341 0 0 0 0 0 0 0 0 0 0 200675 0 0 0 110462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217433 0 199730 243403 0 305923 0 261951 0 0 0 0 189109 122065 131847 0 209645 261718 552513 405226 0 709563 0 0 0 0 0 0 0 166788 227152 0 0 0 0 428744 0 0 2231405 0 3992888 3502307 0 2807449 0 3247484 0 0 0 2200818 2702016 2910195 3783665 0 5345900 6694484 2336939 2646082 0 4181194 0 0 0 0 3227904 4474240 0 2358576 1787775 0 0 0 0 2529452 -(glycidamide)HFGPTYYAFDMGR MGYG000000074_00680 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1409@1|root,COG1409@2|Bacteria,4NF9K@976|Bacteroidetes,2FPK8@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 C terminal of Calcineurin-like phosphoesterase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Metallophos,MetallophosC,MetallophosN,PQQ_2,PQQ_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 74796 0 0 0 0 0 77168 0 101923 0 0 0 0 0 0 0 0 0 0 0 0 0 115557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79656 0 0 0 0 0 0 0 72127 0 0 0 0 0 88258 104813 0 0 0 0 0 0 0 0 0 85634 71387 0 90115 83691 0 0 0 0 0 0 68917 0 1476840 0 946451 0 1396508 1143513 0 1245734 1392259 1190858 0 0 0 946820 1224003 1014618 1334829 0 1741689 0 0 1174221 0 1144432 0 1613522 1170807 0 1465981 2068138 0 0 719333 0 0 0 1419250 1009273 -(glycidamide)IDEYFGLETLK MGYG000000036_01966;MGYG000000142_00583;MGYG000000212_00914;MGYG000000216_00022;MGYG000000038_02280;MGYG000000171_01362;MGYG000002279_00145 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 1.0 rpsI 1.0 - 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 868773 0 0 141462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)IGGGMGC(Carbamidomethyl)STIVERD MGYG000000262_02231;MGYG000000077_02464;MGYG000002517_00540 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 0.6666666666666666 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 957487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)IIAGNIIVR MGYG000002293_01155;MGYG000001770_01237;MGYG000001447_00270;MGYG000003697_02055 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,2FTXU@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL27 family 1.0 rpmA 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02899 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Ribosomal_L27 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1653863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)IIIAAHGNSLR MGYG000002494_00767;MGYG000001613_00806 domain d__Bacteria 1.0 COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,1RNCX@1236|Gammaproteobacteria 0.5 1236|Gammaproteobacteria 0.5 G 1.0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily 0.5 gpmA 1.0 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 0.5 5.4.2.11 0.5 ko:K01834 0.5 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 0.5 M00001,M00002,M00003 0.5 R01518 0.5 RC00536 0.5 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.5 - 1.0 - 1.0 - 1.0 His_Phos_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent). phosphoglyceromutase. The enzymes from vertebrates, platyhelminths, mollusks, annelids, crustaceans, insects, algae, some fungi, yeast and some bacteria (particularly Gram-negative) require 2,3-bisphospho-D-glycerate as a cofactor.-!-The enzyme is activated by 2,3-bisphospho-D-glycerate by transferring a phosphate to histidine (His(10) in man and Escherichia coli, His(8) in Saccharomyces cerevisiae).-!-This phosphate can be transferred to the free OH of 2-phospho-D- glycerate, followed by transfer of the phosphate already on the phosphoglycerate back to the histidine. cf. EC 5.4.2.12.-!-The enzyme has no requirement for metal ions.-!-This enzyme also catalyze, slowly, the reactions of EC 5.4.2.4.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 0.5 0.5 0.5 0.5 Methane metabolism;Carbon metabolism;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Glucagon signaling pathway;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1719567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)IPEYQYQISK MGYG000002517_00722 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 416962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287061 0 0 0 0 0 0 317870 0 0 429172 433415 0 0 0 0 0 0 0 0 396957 0 409326 0 0 0 0 0 272625 293740 383180 0 0 706256 0 0 0 422608 503463 490222 438957 0 4664027 0 0 5781183 0 0 2541281 5840523 5548346 0 0 2723194 0 0 0 2509041 4752302 0 4935116 0 0 0 0 0 5957128 4988744 5611902 0 0 4632889 0 0 0 3076880 5071938 4404143 6248733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)IPHISTGDIFR MGYG000000002_00861 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A faecis|m__MGYG000000002 1.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3XZAB@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism 1.0 adk 1.0 - 1.0 2.7.4.3 1.0 ko:K00939 1.0 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 1.0 M00049 1.0 R00127,R01547,R11319 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS20110 1.0 ADK,ADK_lid 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adenylate kinase. myokinase. Inorganic triphosphate can also act as donor. AMP + ATP = 2 ADP. 1.0 1.0 1.0 1.0 Thiamine metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1347316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)KFGDLENPLLVSVR MGYG000004221_00458;MGYG000000013_03892;MGYG000002006_01658;MGYG000002099_01951;MGYG000000278_00304;MGYG000002727_00240;MGYG000000245_03386;MGYG000003547_00119;MGYG000002478_03849;MGYG000001780_04079;MGYG000002103_01314;MGYG000002455_03526;MGYG000001707_02428;MGYG000003504_01005;MGYG000004663_01541;MGYG000000194_03193;MGYG000004732_02304;MGYG000003412_01990;MGYG000003422_01232;MGYG000002933_01184;MGYG000000196_02017;MGYG000002794_01254;MGYG000000076_02377;MGYG000003312_03561;MGYG000000231_00504;MGYG000000002_01928 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.2692307692307692 186801|Clostridia 0.7307692307692307 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8076923076923077 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 794784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516170 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)LEASGTSGEK MGYG000002549_02274;MGYG000002438_02554;MGYG000001346_00032;MGYG000002478_03973;MGYG000000236_00368;MGYG000001789_02936;MGYG000000196_03749 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,2FNN5@200643|Bacteroidia,4AP04@815|Bacteroidaceae 0.8571428571428571 976|Bacteroidetes 1.0 G 1.0 COG0058 Glucan phosphorylase 0.8571428571428571 glgP 1.0 - 1.0 2.4.1.1,2.4.1.11,2.4.1.8 1.0 ko:K00688,ko:K00691,ko:K16153 1.0 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 1.0 - 1.0 R00292,R01555,R02111 1.0 RC00005,RC00049 1.0 ko00000,ko00001,ko01000,ko01003 1.0 - 1.0 GH65,GT3,GT35 1.0 - 1.0 DUF3417,Glycogen_syn,Phosphorylase 1.0 2.4.1.1 1.0 GT35 1.0 GT35 1.0 GT35 1.0 glycogen phosphorylase. | glycogen(starch) synthase. | maltose phosphorylase. polyphosphorylase. | UDP-glucose--glycogen glucosyltransferase. This entry covers several enzymes from different sources that act in vivo on different forms of (1->4)-alpha-D-glucans.-!-Some of these enzymes catalyze the first step in the degradation of large branched glycan polymers - the phosphorolytic cleavage of alpha-1,4-glucosidic bonds from the non-reducing ends of linear poly(1->4)-alpha-D-glucosyl chains within the polymers.-!-The enzyme stops when it reaches the fourth residue away from an alpha-1,6 branching point, leaving a highly branched core known as a limit dextrin.-!-The description (accepted name) of the enzyme should be modified for each specific instance by substituting 'glycogen' with the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, etc. | The description (official name) varies according to the source of the enzyme and the nature of its synthetic product.-!-Glycogen synthase from animal tissues is a complex of a catalytic subunit and the protein glycogenin.-!-The enzyme requires glucosylated glycogenin as a primer; this is the reaction product of EC 2.4.1.186.-!-A similar enzyme utilizes ADP-glucose (cf. EC 2.4.1.21). [(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. | [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D- glucosyl](n+1) + H(+) + UDP. | D-maltose + phosphate = beta-D-glucose 1-phosphate + D-glucose. 1.0 1.0 1.0 1.0 Necroptosis;Biofilm formation - Escherichia coli;Metabolic pathways;Starch and sucrose metabolism;Insulin resistance;Glucagon signaling pathway;Biosynthesis of secondary metabolites;Insulin signaling pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1389916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)LEEAGAEVEVK MGYG000000170_00066 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900240235|m__MGYG000000170 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5505603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)LNYFVDTKNVA MGYG000000243_01886 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 24772530 0 0 0 24214893 0 0 0 0 26992665 0 0 23821841 0 0 0 0 0 0 0 23454166 0 32415937 0 0 0 0 35320566 36321383 0 38004034 0 0 0 0 0 0 0 295829 0 0 0 395601 0 0 0 0 301768 0 0 454401 0 0 0 0 0 0 0 359651 0 377597 0 0 0 0 549812 225917 0 464057 0 0 0 0 0 0 0 3892014 0 0 0 4905771 0 0 0 0 4306023 0 0 4671543 0 0 0 0 0 0 0 4511869 0 0 0 0 0 0 5278711 4313046 0 4290712 0 0 0 0 0 0 0 0 0 0 0 216158 0 0 0 0 0 0 0 331610 0 0 0 0 0 0 0 319083 0 247889 0 0 0 0 258671 298855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)MGPPQADVALR MGYG000001651_01266 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Anaerovoracaceae|g__UBA1191|s__UBA1191 sp900545775|m__MGYG000001651 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36EI7@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2888201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)MVVQHNLTAM(Oxidation)NANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)NFSFQVEEITR MGYG000000243_00698 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia,4AK9A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 peptidyl-prolyl cis-trans isomerase (trigger factor) 1.0 tig 1.0 - 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)NLDNVVENTTSAESR MGYG000004271_00134 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 751811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)PVQVNEAAGFVVNR MGYG000004732_01389;MGYG000000325_01144;MGYG000002517_00541;MGYG000001255_01113;MGYG000000245_02020;MGYG000002492_00658 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 0.6666666666666666 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Benzoate degradation;Butanoate metabolism;Metabolic pathways;Phenylalanine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3439355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)QIEETTSDFDREK MGYG000000919_03652;MGYG000000202_00541;MGYG000002992_01078;MGYG000000038_02089;MGYG000003486_00745;MGYG000001607_00737;MGYG000001496_00484;MGYG000000278_02028;MGYG000000179_05119;MGYG000001615_01161;MGYG000000198_00464;MGYG000002445_00865;MGYG000000217_01904;MGYG000003783_01372;MGYG000001367_02937;MGYG000001688_01574;MGYG000001617_04641;MGYG000004087_02347;MGYG000000262_01443;MGYG000001193_01063;MGYG000002247_01828;MGYG000002279_00394 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,21YIV@1506553|Lachnoclostridium 0.4090909090909091 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.9545454545454546 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1127131 0 0 0 0 0 1696852 0 0 0 0 0 0 0 0 0 1959435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1251695 -(glycidamide)QLIYTAR MGYG000000127_04024;MGYG000000262_02232;MGYG000000077_02465;MGYG000001707_00050 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,36EDS@31979|Clostridiaceae 0.5 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 1.0 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 3057320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)SGEFLPC(Carbamidomethyl)VFHVSAR MGYG000004763_00186 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 605230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)TCDDIAAC(Carbamidomethyl)AGDTSIALSR MGYG000000171_00277 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3XZR6@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Acetyl-CoA carboxylase alpha subunit 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 740101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)TVVTSMEMFRK MGYG000001500_01929 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter asaccharolyticus|m__MGYG000001500 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,267PG@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)VITSFAGLR MGYG000002298_00538;MGYG000000038_01495;MGYG000000280_01802;MGYG000000404_00180;MGYG000001619_01503;MGYG000002312_03079;MGYG000000171_00187;MGYG000000255_01681;MGYG000000164_01752;MGYG000000271_03444;MGYG000001683_00852;MGYG000000301_00532;MGYG000002517_00473;MGYG000001311_02981;MGYG000000489_00238;MGYG000000154_01590;MGYG000000142_00484;MGYG000000153_02080;MGYG000000076_01007;MGYG000004087_02481;MGYG000002946_03411;MGYG000000245_01076;MGYG000000031_00359;MGYG000000205_00110;MGYG000002276_00835;MGYG000003074_00570;MGYG000000127_02775;MGYG000000179_02173;MGYG000002279_02522;MGYG000001315_01114;MGYG000004271_01228;MGYG000000212_00378;MGYG000000198_04022 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 0.30303030303030304 186801|Clostridia 1.0 S 0.6060606060606061 FAD dependent oxidoreductase 0.5151515151515151 - 0.9090909090909091 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1583490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 677823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)VNFSLEGK MGYG000000243_01545 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,2FMSH@200643|Bacteroidia,4AKTZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Oxidoreductase, short chain dehydrogenase reductase family protein 1.0 idnO 1.0 - 1.0 1.1.1.69 1.0 ko:K00046 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 gluconate 5-dehydrogenase. 5-ketogluconate reductase. - (1) D-gluconate + NADP(+) = 5-dehydro-D-gluconate + H(+) + NADPH. (2) D-gluconate + NAD(+) = 5-dehydro-D-gluconate + H(+) + NADH. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1440353 1633346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)VPAYTVGMVC(Carbamidomethyl)GSGMK MGYG000002953_03277 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__UMGS1202|s__UMGS1202 sp900549565|m__MGYG000002953 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2148423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)YDSSQGKYALADTVSAGEDSITVDGK MGYG000000280_02459;MGYG000000164_00800 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)YIIAPDGLK MGYG000003449_00709 genome d__Bacteria|p__Verrucomicrobiota|c__Verrucomicrobiae|o__Opitutales|f__CAG-312|g__CAG-312|s__CAG-312 sp002405555|m__MGYG000003449 1.0 COG0090@1|root,COG0090@2|Bacteria,46S71@74201|Verrucomicrobia,3K7DN@414999|Opitutae 1.0 414999|Opitutae 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 3193289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)YSLNDIC(Carbamidomethyl)DEWSR MGYG000003697_02405 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,2FNRM@200643|Bacteroidia,4AKT2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 565123 0 1366556 0 0 0 1735198 0 0 0 0 0 7539486 0 0 0 0 0 0 0 1432598 0 4326667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)YTSFAGAPEDAESSVK MGYG000002223_00841;MGYG000001300_02394 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3WGGJ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1357134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(glycidamide)YYFDTDGK MGYG000000233_01872;MGYG000000205_02372 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG5263@1|root,COG5263@2|Bacteria,1UY86@1239|Firmicutes,24EH1@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Cell wall-binding repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34952186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(iTRAQ4plex[AnyN-term](mTRAQ_13C(3)15N(1))KNEGIESIMAVYKK MGYG000002438_01883 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 435591.BDI_2653|- 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(mTRAQ)GTTSVMFSEVANAPAK MGYG000000273_00425;MGYG000004185_01219;MGYG000002478_00808;MGYG000004797_04277 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,2FSBB@200643|Bacteroidia,22XXG@171551|Porphyromonadaceae 0.75 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 0.75 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(mTRAQ)MASIEAALEKGDVEAAK MGYG000001378_04234;MGYG000000029_00498;MGYG000000196_02323;MGYG000001345_03404;MGYG000000013_01747;MGYG000001433_03806;MGYG000002549_04269;MGYG000000054_02343;MGYG000000098_00597 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1782863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(mTRAQ_13C(6)15N(2))ADMVDDAELLELVEMEVR MGYG000002485_02622;MGYG000001485_02164 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,3784P@32066|Fusobacteria 0.5 32066|Fusobacteria 0.5 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.5 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(mTRAQ_13C(6)15N(2))AHIAELAVGDAC(Carbamidomethyl)TGSNPR MGYG000004558_00984 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__|m__MGYG000004558 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 962653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -(mTRAQ_13C(6)15N(2))GGTVTNVDEWGK MGYG000000179_03534;MGYG000004087_00279;MGYG000000198_04385 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,220M9@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Binds together with S18 to 16S ribosomal RNA 1.0 rpsF 1.0 - 1.0 - 1.0 ko:K02990 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5512810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asn)DLKDVEDSNLGLK MGYG000000312_02426;MGYG000003486_02521 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 573957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 783466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 836698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asn)GIGDLVTYEVK MGYG000000099_01985 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0860@1|root,COG0860@2|Bacteria,1UMXD@1239|Firmicutes,25GRN@186801|Clostridia,26CS5@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 M 1.0 S-layer homology domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2224888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 956529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asn)GILFAPGK MGYG000003542_01587;MGYG000001302.1_00046;MGYG000000053_01686 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdh 1.0 GO:0005575,GO:0005623,GO:0009986,GO:0044464 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asn)VVDAGWMTADHQVGQTGK MGYG000002720_01216 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WCFX@538999|Clostridiales incertae sedis 1.0 186801|Clostridia 1.0 C 1.0 PFAM Electron transfer flavoprotein domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 2408707 0 1701168 0 0 0 0 0 0 0 0 2532045 0 0 0 0 0 0 0 0 2067807 0 0 0 0 2563948 0 0 2325658 0 0 0 0 3045389 0 0 0 0 0 0 368439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asn)YLEAWDTYKEGEK MGYG000004797_03700 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,2FN8P@200643|Bacteroidia,4AMSQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 COG NOG06391 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4301 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340742 0 0 0 0 477947 0 0 0 0 1078780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asp)AAAAAEAEAK MGYG000002293_01607 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1649360 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asp)AASESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asp)AGGVILITTK MGYG000002438_00861;MGYG000002218_02008;MGYG000000355_00074;MGYG000002478_00138;MGYG000002834_00163;MGYG000001489_04986;MGYG000003521_00292;MGYG000001666_00694;MGYG000003697_02612;MGYG000002080_00857 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 0.4 976|Bacteroidetes 1.0 P 0.9 TonB-linked outer membrane protein, SusC RagA family 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 891729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asp)ATFNTVYC(Carbamidomethyl)C(Carbamidomethyl)FYK MGYG000002478_01081 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2954226 3336163 7312666 0 0 2432910 4786412 0 0 2558802 0 0 0 0 0 0 3495964 982587 2088032 0 0 2347008 1886939 4267095 2092491 2248739 3580436 1806269 3568438 0 0 0 8961813 0 3064044 0 2955322 8199940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asp)AYLFNHVEYR MGYG000004893_00001 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A sp900555485|m__MGYG000004893 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,378RN@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 851623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asp)HANADDTWK MGYG000001619_00313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA9502|s__UBA9502 sp900540335|m__MGYG000001619 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2129521 0 1607912 0 0 3887362 0 0 0 0 1521412 0 754366 0 0 0 0 0 0 0 0 -A(Ala->Asp)LVDGAPK MGYG000003166_01197;MGYG000000053_00901;MGYG000001292_02396;MGYG000001597_00990;MGYG000002619_00763;MGYG000003872_00167;MGYG000001255_00183;MGYG000002082_01855;MGYG000003683_01183;MGYG000001562_01082;MGYG000003279_00958;MGYG000000130_00379;MGYG000000756_00072;MGYG000004006_00426;MGYG000002610_00935;MGYG000002545_02317;MGYG000000258_01583;MGYG000003899_00430;MGYG000001546_01548;MGYG000002977_00165;MGYG000002867_00700;MGYG000003307_00505;MGYG000001420_00134;MGYG000000039_01033;MGYG000002007_00362;MGYG000001300_02635;MGYG000000003_02516;MGYG000002224_00796;MGYG000001613_01124;MGYG000002040_00800;MGYG000001497_00224;MGYG000004158_00987;MGYG000002203_00881;MGYG000000195_00269;MGYG000004756_01180;MGYG000001660_01967;MGYG000003730_01040;MGYG000000074_01766;MGYG000003509_00721;MGYG000002651_00254;MGYG000003542_00372;MGYG000004658_01198;MGYG000000414_00669;MGYG000002397_01219;MGYG000002223_01729;MGYG000002274_01731 domain d__Bacteria 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 0.34782608695652173 186801|Clostridia 0.4782608695652174 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 0.8695652173913043 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2876607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asp)MMVGLDGTPEK MGYG000000179_05287 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Arabinose_Isome,Fucose_iso_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 973980 0 0 0 0 0 0 0 516502 366789 0 0 0 0 0 0 0 0 0 665817 583042 0 0 0 0 1086487 972320 0 0 634544 0 0 0 497242 0 617983 576747 0 564517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332433 0 0 0 0 0 0 0 0 0 841318 1448107 0 904739 0 0 0 0 0 901378 0 656043 903881 0 0 0 0 0 0 0 0 0 734464 448942 0 0 0 717860 755218 770413 0 0 756527 597835 0 0 751454 0 683648 947950 0 417706 0 0 0 0 0 520999 0 0 201662 0 0 0 0 0 0 0 0 516719 681976 0 0 0 0 238398 351896 763029 0 0 0 309109 0 0 0 0 695130 685761 0 2293488 0 0 0 0 0 1619232 0 1998695 2507444 0 0 0 0 0 0 0 0 2216599 1581885 2910463 0 0 0 2058404 1986508 2498140 0 0 1627389 3749019 0 0 1936427 0 1904274 1629459 0 -A(Ala->Asp)SGRFDDEIVPVPVK MGYG000004482_00909;MGYG000000377_01679 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,2N6SP@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 1204007 0 0 0 1704631 0 0 0 1484257 0 0 0 0 0 0 1438508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1174352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1272795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Asp)YKPFAPGASPSYGAEK MGYG000000217_01657 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Acetatifactor|s__Acetatifactor sp900066565|m__MGYG000000217 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,27J0U@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate formate lyase-like 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8503684 0 0 0 0 7520598 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 499323 0 0 0 0 378587 0 0 0 0 276480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1219198 0 0 0 0 1162782 0 0 0 0 1074145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 630500 0 0 0 0 428592 0 0 0 0 953109 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gln)ADDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1896826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gln)AMEIMR MGYG000002224_01341;MGYG000000084_02152 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes 0.5 1239|Firmicutes 0.5 S 1.0 Myosin-crossreactive antigen 0.5 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5077804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gln)DLKDVDDSNLGLK MGYG000001637_02230;MGYG000000154_01281;MGYG000000217_01341 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.6666666666666666 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1397892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gln)GVKPEMVDEVK MGYG000004271_00231;MGYG000000489_01023;MGYG000000271_02104;MGYG000000280_01473;MGYG000001637_02269;MGYG000003694_00877 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 3126235 2866097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4865524 3228802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)AAGTAAVSAAEQTK MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1068014 0 0 0 0 1228467 -A(Ala->Glu)AASESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)AASSFNK MGYG000000198_05930 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Cell wall-binding repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1136627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 214330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)ATPLAK MGYG000002279_01986;MGYG000000359_00714 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2995274 2555781 0 0 0 0 0 0 0 0 0 0 0 1281050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1067180 1303409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4974681 6205444 0 0 0 0 0 0 0 0 0 0 0 3806399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 377317 413854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)AWDALTDAQK MGYG000002720_00991;MGYG000002040_00824;MGYG000002143_00828;MGYG000000369_00585;MGYG000000022_00190;MGYG000002517_01775;MGYG000000489_00610;MGYG000001300_00328;MGYG000002993_01434 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,2N7HM@216572|Oscillospiraceae 0.4444444444444444 186801|Clostridia 1.0 H 1.0 Cobalt chelatase (CbiK) 0.5555555555555556 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 0.6666666666666666 - 1.0 - 1.0 - 0.8888888888888888 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 694751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)EREAAEQAK MGYG000002506_02810 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,3XMNK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 681122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)GLAGLEITC(Carbamidomethyl)PK MGYG000000802_01545;MGYG000000188_00827;MGYG000000333_00450;MGYG000004746_01526;MGYG000002968_00326;MGYG000003274_01601;MGYG000002947_01134;MGYG000003851_00621;MGYG000002065_00755;MGYG000002970_00371;MGYG000002775_01124 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0696@1|root,COG0696@2|Bacteria,2HHGK@201174|Actinobacteria,4CUJ8@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 - 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Metalloenzyme,Phosphodiest,Sulfatase,iPGM_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1232692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)GTLAVAK MGYG000001300_02037;MGYG000000233_00344 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 G 0.5 Phosphoglycerate kinase 0.5 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 687734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3289688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1965310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)GVTADSIAK MGYG000002720_01849;MGYG000004487_00561 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,2N6SP@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7476411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8545539 0 0 0 0 0 0 4164682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)IPHVEIVR MGYG000002720_00860;MGYG000004573_00975;MGYG000002926_00665;MGYG000004525_00411;MGYG000002143_01958;MGYG000003919_00339;MGYG000001733_00673;MGYG000004196_01674;MGYG000002574_02767;MGYG000004487_00298;MGYG000001502_02361 domain d__Bacteria 1.0 COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,25UUF@186806|Eubacteriaceae 0.6363636363636364 186801|Clostridia 0.7272727272727273 E 0.7272727272727273 Lysine-2,3-aminomutase 0.9090909090909091 kamA 0.7272727272727273 - 1.0 5.4.3.2 0.9090909090909091 ko:K01843 0.9090909090909091 ko00310,map00310 1.0 - 1.0 R00461 1.0 RC00303 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,LAM_C,Radical_SAM 0.8181818181818182 - 1.0 - 1.0 - 1.0 - 1.0 lysine 2,3-aminomutase. - This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-It contains pyridoxal phosphate and a [4Fe-4S] cluster and binds an exchangeable S-adenosyl-L-methionine molecule.-!-Activity in vitro requires a strong reductant such as dithionite and strictly anaerobic conditions.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of S-adenosyl-L-methionine, mediated by the iron- sulfur cluster.-!-S-adenosyl-L-methionine is regenerated at the end of the reaction. L-lysine = (3S)-3,6-diaminohexanoate. 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Lysine degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)ITGLGLAEAK MGYG000002026_00911 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__HGM13010|s__HGM13010 sp900754965|m__MGYG000002026 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,269AI@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1900027 0 0 0 0 -A(Ala->Glu)IVKNPGESC(Carbamidomethyl)DEK MGYG000000164_00379;MGYG000000133_02152;MGYG000000249_00984;MGYG000002772_01083;MGYG000001714_00588 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,36G77@31979|Clostridiaceae 0.4 186801|Clostridia 1.0 E 1.0 peptidase 0.4 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 388601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 899944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)KEKFER MGYG000000042_01421;MGYG000002106_00224;MGYG000001524_01606;MGYG000001630_01142;MGYG000002485_02622;MGYG000004893_01944;MGYG000004893_00932;MGYG000003460_01161;MGYG000003155_00314;MGYG000001925_01419;MGYG000000273_00431;MGYG000001701_00473;MGYG000004763_01689;MGYG000003681_02037;MGYG000001384_04567;MGYG000001464_00103;MGYG000002281_02290;MGYG000003185_01074;MGYG000003992_01709;MGYG000003142_01879;MGYG000002528_01098;MGYG000001313_00097;MGYG000000013_02251;MGYG000003266_00392;MGYG000003583_01411;MGYG000002455_03884;MGYG000000348_00283;MGYG000003628_01000;MGYG000001485_02164;MGYG000000034_01346;MGYG000001141_02439;MGYG000002930_00867;MGYG000003142_01865;MGYG000000196_03974;MGYG000003375_00698;MGYG000004573_00004;MGYG000001661_02666;MGYG000003851_00676;MGYG000002762_01733;MGYG000000121_02189;MGYG000001789_00154;MGYG000001567_01738;MGYG000000182_00585;MGYG000000054_03933;MGYG000000236_01807;MGYG000000098_02017;MGYG000002291_02272;MGYG000003185_01053;MGYG000002556_01332;MGYG000000036_01380;MGYG000000445_01370;MGYG000001346_01533;MGYG000000243_01988;MGYG000001780_03476;MGYG000002540_03367;MGYG000001646_01118;MGYG000003073_01160;MGYG000003514_00785;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.23728813559322035 976|Bacteroidetes 0.4915254237288136 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9830508474576272 tuf 1.0 - 0.847457627118644 - 1.0 ko:K02358 0.9830508474576272 - 0.9830508474576272 - 0.9830508474576272 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9830508474576272 - 0.9830508474576272 - 1.0 - 0.9491525423728814 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9830508474576272 none 1.0 0 0 0 0 0 0 0 3919345 0 0 0 0 0 4818233 0 1044038 0 0 0 0 2631983 4751343 0 0 2753006 0 0 0 0 2954044 0 0 0 3183946 0 0 0 0 0 0 0 0 0 3511410 0 1107512 0 0 0 0 0 1798820 0 1762084 0 0 0 0 1669775 0 0 3033570 2302140 0 0 0 0 1591621 0 0 0 1699616 0 0 0 0 0 0 0 0 0 5573936 0 3841690 0 0 0 0 0 1911641 0 2453630 0 0 0 0 1829163 3576849 0 0 2809754 0 0 0 0 2124568 0 0 0 3364226 0 0 0 0 0 0 0 0 0 6391476 0 5353453 0 0 0 0 0 3168782 0 2634152 0 0 0 0 1587189 5686151 0 5816077 4879284 0 0 0 0 4416713 0 0 0 6803715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)LADSVHAYGTK MGYG000000022_00970 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WH0G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 NADH oxidase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Oxidored_FMN,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438990 0 0 0 0 443676 0 0 0 0 449591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1271412 0 0 0 0 1549090 0 0 0 0 1372584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)LC(Carbamidomethyl)DTLEGDER MGYG000002223_00163;MGYG000001255_00186;MGYG000002105_01626;MGYG000001300_01405;MGYG000000022_01398 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3WGUG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 804404 0 0 0 0 0 0 0 0 0 0 0 0 1028425 0 0 0 0 0 1081770 0 0 0 0 0 649323 633288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 621206 0 0 615759 0 823672 0 0 736944 0 0 0 0 0 0 0 0 0 0 0 762141 0 492493 0 0 0 0 0 0 0 0 0 654755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)LNDIYYGR MGYG000002082_01706 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900544265|m__MGYG000002082 1.0 COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,2FN0N@200643|Bacteroidia,22UX5@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Aminotransferase class I and II 1.0 dapL 1.0 - 1.0 2.6.1.83 1.0 ko:K10206,ko:K14261 1.0 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 1.0 M00527 1.0 R07613 1.0 RC00006,RC01847 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 LL-diaminopimelate aminotransferase. LL-diaminopimelate transaminase. In vivo, the reaction occurs in the opposite direction to that shown above.-!-This is one of the final steps in the lysine biosynthesis pathway of plants (ranging from mosses to flowering plants).-!-Meso-diaminoheptanedioate, an isomer of LL-2,6-diaminoheptanedioate, and the structurally related compounds lysine and ornithine are not substrates.-!-2-oxoglutarate cannot be replaced by oxaloacetate or pyruvate.-!-It is not yet known if the substrate of the biosynthetic reaction is the cyclic or acyclic form of tetrahydropyridine-2,6-dicarboxylate. (2S,6S)-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5- tetrahydrodipicolinate + H(+) + H2O + L-glutamate. 1.0 1.0 1.0 1.0 Lysine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2059706 0 2165651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)LNLTATLDGAK MGYG000002549_04177 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,2FMZ9@200643|Bacteroidia,4AM97@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family 1.0 ugd 1.0 - 1.0 1.1.1.22 1.0 ko:K00012 1.0 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 1.0 M00014,M00129,M00361,M00362 1.0 R00286 1.0 RC00291 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 UDP-glucose 6-dehydrogenase. - Also acts on UDP-2-deoxyglucose. H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D- glucuronate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose and glucuronate interconversions;Ascorbate and aldarate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 936902 0 0 0 0 0 0 0 -A(Ala->Glu)MGFEVIDC(Carbamidomethyl)NESDPVEK MGYG000002528_02461 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG1063@1|root,COG1063@2|Bacteria,1V0K3@1239|Firmicutes,24DWK@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1267392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633753 0 1840454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)SGAGGQC(Carbamidomethyl)VNTTDSAVR MGYG000000271_00850;MGYG000000245_01524;MGYG000003422_01334;MGYG000004271_01559 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA 1.0 prfA 1.0 - 1.0 - 1.0 ko:K02835 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 PCRF,RF-1 1.0 - 1.0 - 1.0 - 1.0 GH23 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 414904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1232064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)TDQPFLMPVEDVFTITGR MGYG000004735_00884 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230735535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)TTDKLAGILAAK MGYG000002720_01505 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,2N6RS@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 968332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)TTEQAQEVC(Carbamidomethyl)AGIR MGYG000001338_02545 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 895683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1130943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3204444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)TVIALNVR MGYG000001346_01583 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1196@1|root,COG1196@2|Bacteria,4PIVU@976|Bacteroidetes,2FQ1R@200643|Bacteroidia,4APFX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 D 1.0 Domain of unknown function 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 5530829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)VDC(Carbamidomethyl)DEAVAR MGYG000001225_01793 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Evtepia|s__Evtepia sp004556345|m__MGYG000001225 1.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3WGQA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 acetylornithine aminotransferase 1.0 argD 1.0 - 1.0 2.6.1.11,2.6.1.17 1.0 ko:K00821 1.0 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00028,M00845 1.0 R02283,R04475 1.0 RC00006,RC00062 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetylornithine transaminase. | succinyldiaminopimelate transaminase. succinylornithine aminotransferase. | succinyldiaminopimelate transferase. Also acts on L-ornithine and N(2)-succinyl-L-ornithine. 2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L- glutamate 5-semialdehyde. | 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (S)-2- succinylamino-6-oxoheptanedioate + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Lysine biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5615095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)VSMEDIK MGYG000003535_00725 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp004556065|m__MGYG000003535 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 1279284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2378081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Glu)VSMEDIKK MGYG000003535_00725 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp004556065|m__MGYG000003535 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3352195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)AHFGNNVSHSHR MGYG000000184_00823;MGYG000001338_01758 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL28 family 1.0 rpmB 1.0 - 1.0 - 1.0 ko:K02902 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 480084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112079 0 0 0 0 202047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2030210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2677053 0 0 0 0 1126511 -A(Ala->Gly)AMLAIMNPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)AMLTIMNPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)ASEFEALR MGYG000002717_02115;MGYG000001661_02103;MGYG000001313_03171;MGYG000000098_00636;MGYG000000054_02931;MGYG000000196_02287;MGYG000003681_00141;MGYG000004763_00640;MGYG000001346_00856 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 0.8888888888888888 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 0.8888888888888888 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)DDIALLK MGYG000001599_02718 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900544075|m__MGYG000001599 1.0 COG4115@1|root,COG4115@2|Bacteria,4NUMR@976|Bacteroidetes,2FUIS@200643|Bacteroidia,4ASEK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 YoeB-like toxin of bacterial type II toxin-antitoxin system 1.0 - 1.0 - 1.0 - 1.0 ko:K19158 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko02048 1.0 - 1.0 - 1.0 - 1.0 YoeB_toxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 486833 0 0 0 0 505921 0 0 0 0 408452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275804 0 0 0 0 0 0 0 0 0 182765 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253129 0 0 0 0 228660 0 0 0 0 198197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2630328 0 0 0 0 2417287 0 0 0 0 2644608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394309 0 0 0 0 299529 0 0 0 0 317346 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)IYVVLDK MGYG000000243_01886;MGYG000002171_01694 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 5315458 0 0 0 0 4961401 0 0 7676985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1524411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)LGLLFAPEKGEDTR MGYG000000196_04764;MGYG000003681_01676;MGYG000000105_00790;MGYG000000236_02677;MGYG000001461_03645;MGYG000001345_02126;MGYG000004876_01798;MGYG000004899_00075 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4980@1|root,COG4980@2|Bacteria,4NXMW@976|Bacteroidetes,2FUB7@200643|Bacteroidia,4ARS7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG35214 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 YtxH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)LLDYLK MGYG000000236_03731 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,2FTTZ@200643|Bacteroidia,4ARAW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1064534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)NPILLEPIMK MGYG000003423_00914 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__W3P20-009|g__W3P20-009|s__W3P20-009 sp900766825|m__MGYG000003423 1.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,47M8E@768503|Cytophagia 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 387107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)QLEETTSEFDKEK MGYG000000231_00495;MGYG000004271_02056;MGYG000000187_01409;MGYG000000404_00409;MGYG000000271_00294;MGYG000002528_02459;MGYG000004707_00421;MGYG000001707_02383 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia 0.375 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1085726 0 0 0 0 0 0 0 0 0 1528601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1242457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)QTFELYAIK MGYG000001661_01211;MGYG000003681_02216;MGYG000001313_00227;MGYG000004899_00384 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1496142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)VTETVTQPVGFR MGYG000000074_01087 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,2FM0P@200643|Bacteroidia,22V3F@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Beta galactosidase small chain 1.0 - 1.0 - 1.0 3.2.1.23 1.0 ko:K01190 1.0 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 1.0 - 1.0 R01105,R01678,R03355,R04783,R06114 1.0 RC00049,RC00452 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N 1.0 3.2.1.23 1.0 GH2 1.0 GH2 1.0 GH2 1.0 beta-galactosidase. lactase. Some enzymes in this group hydrolyze alpha-L-arabinosides; some animal enzymes also hydrolyze beta-D-fucosides and beta-D-glucosides (cf. EC 3.2.1.108). Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D- galactosides. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Other glycan degradation;Sphingolipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1861798 0 0 0 0 0 0 0 0 0 0 1503535 0 0 0 0 0 0 0 0 -A(Ala->Gly)VVTAFVDGWAK MGYG000002040_01179;MGYG000000195_01879 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 GH49 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 220751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 725253 0 0 0 0 0 0 0 0 569830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)YASNAANFEDTAK MGYG000001750_01297 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola ilei|m__MGYG000001750 1.0 COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,2FNB4@200643|Bacteroidia,4ANUZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 with different specificities (related to short-chain alcohol 1.0 fabG 1.0 - 1.0 1.1.1.100 1.0 ko:K00059 1.0 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 1.0 M00083,M00572 1.0 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-oxoacyl-[acyl-carrier-protein] reductase. - Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates. a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH. 1.0 1.0 1.0 1.0 Biotin metabolism;Fatty acid metabolism;Fatty acid biosynthesis;Biosynthesis of unsaturated fatty acids;Metabolic pathways;Prodigiosin biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1402348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)YASNAASFEDTAK MGYG000001661_02228;MGYG000003681_02278 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,2FNB4@200643|Bacteroidia,4ANUZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 with different specificities (related to short-chain alcohol 1.0 fabG 1.0 - 1.0 1.1.1.100 1.0 ko:K00059 1.0 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 1.0 M00083,M00572 1.0 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-oxoacyl-[acyl-carrier-protein] reductase. - Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates. a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH. 1.0 1.0 1.0 1.0 Biotin metabolism;Fatty acid metabolism;Fatty acid biosynthesis;Biosynthesis of unsaturated fatty acids;Metabolic pathways;Prodigiosin biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2746067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Gly)YDSFQFVR MGYG000001687_02017;MGYG000000095_04521;MGYG000000271_00685;MGYG000002989_00673;MGYG000002492_01449;MGYG000004271_02184;MGYG000000077_00482;MGYG000002517_01100;MGYG000000359_01824;MGYG000000489_02027 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia 0.8 186801|Clostridia 1.0 J 1.0 Glutaminyl-tRNA synthetase 0.8 glnS 1.0 - 1.0 6.1.1.18 1.0 ko:K01886 1.0 ko00970,ko01100,map00970,map01100 1.0 M00359,M00360 1.0 R03652 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 tRNA-synt_1c,tRNA-synt_1c_C 1.0 - 1.0 - 1.0 - 1.0 CE8 1.0 glutamine--tRNA ligase. glutaminyl-tRNA synthetase. - ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl- tRNA(Gln). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1212869 0 0 0 0 0 0 0 -A(Ala->Lys)AEILQISK MGYG000000427_00123 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__RFN20|f__CAG-449|g__CAG-449|s__CAG-449 sp000432895|m__MGYG000000427 1.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,3VNPX@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 P 1.0 Belongs to the ABC transporter superfamily 1.0 - 1.0 - 1.0 - 1.0 ko:K10112 1.0 ko02010,map02010 1.0 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1 1.0 - 1.0 - 1.0 ABC_tran,TOBE_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 7142402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Lys)DLKPHAPR MGYG000004797_03519 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640364 0 0 0 0 0 0 694096 0 0 0 0 0 0 0 0 0 0 0 0 0 339149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Lys)IAEELVNLTVK MGYG000002540_03361;MGYG000001164_01590;MGYG000001056_00099;MGYG000001659_00517;MGYG000003697_01479;MGYG000004848_00672;MGYG000003374_00514;MGYG000002603_01776;MGYG000002080_00533;MGYG000004495_01664;MGYG000003353_00116;MGYG000002293_00514;MGYG000004757_00587;MGYG000003301_00858 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia 0.5714285714285714 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 933381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Lys)LLDYLK MGYG000000236_03731 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,2FTTZ@200643|Bacteroidia,4ARAW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2454087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2087296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Lys)LSTDLADQGK MGYG000000044_01042 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides merdae|m__MGYG000000044 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1932017 0 1968400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1986937 0 0 0 0 1820454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Lys)SGGGYAISIK MGYG000002171_00690 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002493165|m__MGYG000002171 1.0 COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,2FKZT@200643|Bacteroidia,4AMS4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG NOG06228 non supervised orthologous group 1.0 susB 1.0 GO:0000272,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0004558,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:0090599,GO:1901575 1.0 3.2.1.20,3.2.1.3 1.0 ko:K01187,ko:K21574 1.0 ko00052,ko00500,ko01100,map00052,map00500,map01100 1.0 - 1.0 R00028,R00801,R00802,R01790,R01791,R06087,R06088 1.0 RC00028,RC00049,RC00077 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH31,GH97 1.0 - 1.0 GH97_C,GH97_N,Glyco_hydro_97 1.0 3.2.1.3|3.2.1.20 1.0 GH97 1.0 GH97 1.0 GH97 1.0 alpha-glucosidase. | glucan 1,4-alpha-glucosidase. maltase-glucoamylase. | lysosomal alpha-glucosidase. Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.-!-The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links. | Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides.-!-This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides.-!-EC 3.2.1.20 from mammalian intestine can catalyze similar reactions. Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. | Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3546178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Lys)YENGVLTGK MGYG000002485_00504;MGYG000000233_02492 domain d__Bacteria 1.0 COG0334@1|root,COG0334@2|Bacteria,378XT@32066|Fusobacteria 0.5 32066|Fusobacteria 0.5 C 0.5 Belongs to the Glu Leu Phe Val dehydrogenases family 0.5 gluD 0.5 - 0.5 1.4.1.2,1.4.1.4 0.5 ko:K00260,ko:K00262 0.5 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 0.5 - 0.5 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 0.5 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.5 0.5 0.5 0.5 Taurine and hypotaurine metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Met)LGTGVEKDGNIDSTPVGTNADGTATVVK MGYG000000179_01753 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Phe)NIPGFR MGYG000004797_02839;MGYG000002478_00469;MGYG000000243_00698 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia,4AK9A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 peptidyl-prolyl cis-trans isomerase (trigger factor) 1.0 tig 1.0 - 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 689892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Pro)ADDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 637576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1433019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Pro)EGTPEEIVPAR MGYG000003383_02109;MGYG000001292_00431;MGYG000003683_01237;MGYG000001490_00221;MGYG000002469_00458;MGYG000002395_00255;MGYG000000756_00019 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4CYVV@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGE-sulfatase,Glucosamine_iso,PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 1074458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1262887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1352694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)AASESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 837119 0 0 0 0 0 0 0 2074205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325663 0 0 0 0 533112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)ADDAAGLSISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 2025243 0 0 1878988 1596316 0 0 1289800 0 0 1707062 1212119 0 0 0 0 0 1431711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276437 0 0 0 0 0 0 245164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328597 0 0 0 0 0 462979 493931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475859 0 0 907647 437222 0 0 514312 0 0 643978 571850 0 0 0 0 0 421976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)AGAAGVIRPSK MGYG000001300_00059;MGYG000003899_00538;MGYG000002641_02329;MGYG000002610_01595;MGYG000004719_01899;MGYG000003166_01772;MGYG000003921_01901;MGYG000001157_01521;MGYG000003937_01168;MGYG000000573_01714;MGYG000000589_01770;MGYG000000084_01199;MGYG000004732_01998 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 0.9230769230769231 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 0.9230769230769231 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Phosphotransferase system (PTS) 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 962875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1373515 0 1284797 0 0 0 -A(Ala->Ser)AGNAFFEIAAK MGYG000000216_00086;MGYG000000142_00725 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1879@1|root,COG1879@2|Bacteria,1TRBC@1239|Firmicutes,24APE@186801|Clostridia,3Y16X@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 lsrB 1.0 - 1.0 - 1.0 ko:K10555 1.0 ko02010,ko02024,map02010,map02024 1.0 M00219 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.8 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)ANAGGVATSALEMSQNSER MGYG000002945_01156;MGYG000000080_02138;MGYG000004689_01489;MGYG000000245_02477;MGYG000000135_03486;MGYG000004839_02530;MGYG000000251_03197;MGYG000000146_00040;MGYG000002212_01108;MGYG000000164_00589;MGYG000000153_01021;MGYG000004296_00383;MGYG000004380_02235;MGYG000000404_01723;MGYG000002517_02750;MGYG000001797_03050;MGYG000000312_01079;MGYG000001637_01313;MGYG000001689_00608;MGYG000000489_02253;MGYG000000280_02447;MGYG000002528_01412;MGYG000003425_04268;MGYG000000076_02271;MGYG000004879_02390;MGYG000000229_01813;MGYG000002670_01100;MGYG000000136_01003;MGYG000002609_02276;MGYG000004719_01514;MGYG000004547_00997;MGYG000003702_00540;MGYG000004055_01618;MGYG000003063_02071;MGYG000000187_02311;MGYG000002279_01299;MGYG000002149_01514;MGYG000002992_01902;MGYG000000271_00907;MGYG000002492_02848;MGYG000002131_02188 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.3170731707317073 186801|Clostridia 0.6829268292682927 C 0.4146341463414634 Belongs to the Glu Leu Phe Val dehydrogenases family 0.4634146341463415 gdhA 0.6829268292682927 - 1.0 1.4.1.3,1.4.1.4 0.6341463414634146 ko:K00261,ko:K00262 0.6341463414634146 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6341463414634146 M00740 0.6829268292682927 R00243,R00248 0.6829268292682927 RC00006,RC02799 0.6829268292682927 ko00000,ko00001,ko00002,ko01000,ko04147 0.6829268292682927 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.6829268292682927 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6341463414634146 0.6341463414634146 0.6341463414634146 0.6341463414634146 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.6341463414634146 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1269544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)ANLPEAMIQNIAK MGYG000002171_01964 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002493165|m__MGYG000002171 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 649501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1553269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1278607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)ANVTLVGYEK MGYG000001065_00275;MGYG000001622_00878 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11942269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42021232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49150122 0 -A(Ala->Ser)APILLEPIMR MGYG000000171_02843;MGYG000004733_01212 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)ATDGPMPQTR MGYG000000042_01421;MGYG000004732_02398;MGYG000004464_00178;MGYG000002619_00483;MGYG000000412_01546;MGYG000004848_00666;MGYG000004565_01266;MGYG000003353_00058;MGYG000003189_00640;MGYG000003460_01161;MGYG000003324_00542;MGYG000001806_01406;MGYG000001701_00473;MGYG000004763_01689;MGYG000003681_02037;MGYG000003184_03610;MGYG000003363_01661;MGYG000003937_01027;MGYG000001234_01151;MGYG000001770_01653;MGYG000003992_01709;MGYG000001313_00097;MGYG000002654_00465;MGYG000004629_00424;MGYG000002455_03884;MGYG000000348_00283;MGYG000002515_03657;MGYG000000044_01721;MGYG000001360_01239;MGYG000002834_01866;MGYG000003549_00407;MGYG000003189_01066;MGYG000002059_00460;MGYG000003152_01866;MGYG000000196_03974;MGYG000004588_00463;MGYG000003375_00698;MGYG000004573_00004;MGYG000001713_03599;MGYG000001661_02666;MGYG000003374_00521;MGYG000001300_00280;MGYG000001635_01137;MGYG000002762_01733;MGYG000003334_00997;MGYG000002040_01212;MGYG000000054_03933;MGYG000002293_00521;MGYG000000098_02017;MGYG000002080_00527;MGYG000001359_01254;MGYG000002438_02321;MGYG000002556_01332;MGYG000003410_00864;MGYG000001346_01533;MGYG000002976_00273;MGYG000001763_00317;MGYG000003812_01875;MGYG000003497_00215;MGYG000004754_01565;MGYG000001692_03322;MGYG000002768_00022;MGYG000003921_01124;MGYG000002996_00986;MGYG000002418_00753;MGYG000002506_03686;MGYG000000168_03211;MGYG000001334_00218;MGYG000004757_00594;MGYG000001487_02232;MGYG000000138_00665;MGYG000002603_01782;MGYG000001630_01142;MGYG000001516_01186;MGYG000000215_00564;MGYG000002535_04656;MGYG000001925_01419;MGYG000002515_03208;MGYG000000273_00431;MGYG000003372_03275;MGYG000004788_02115;MGYG000000230_00429;MGYG000003202_00129;MGYG000002281_02290;MGYG000002506_02966;MGYG000001400_03001;MGYG000003546_00955;MGYG000001554_00107;MGYG000000022_02283;MGYG000002470_01245;MGYG000003446_00658;MGYG000001552_00984;MGYG000002514_02415;MGYG000003899_01642;MGYG000000013_02251;MGYG000003691_01713;MGYG000003394_01668;MGYG000002895_00716;MGYG000002951_00422;MGYG000003697_01485;MGYG000000134_02651;MGYG000001784_02227;MGYG000002507_00346;MGYG000001655_02933;MGYG000000173_00405;MGYG000002220_00457;MGYG000002195_01684;MGYG000000226_00644;MGYG000002930_00867;MGYG000003166_01350;MGYG000002905_00001;MGYG000001590_00854;MGYG000002444_02629;MGYG000002514_01953;MGYG000002912_01340;MGYG000003424_00456;MGYG000001789_00154;MGYG000000236_01807;MGYG000003701_03123;MGYG000000084_02000;MGYG000002291_02272;MGYG000002502_01846;MGYG000004300_00119;MGYG000002641_00069;MGYG000000733_01034;MGYG000002997_01472;MGYG000004221_01651;MGYG000002272_01482;MGYG000000622_01283;MGYG000000243_01988;MGYG000001780_03476;MGYG000000045_02616;MGYG000002540_03367;MGYG000001421_00009;MGYG000000254_02569;MGYG000003660_00194;MGYG000003514_00785;MGYG000003620_01283;MGYG000000117_01463;MGYG000003535_00219;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.1773049645390071 976|Bacteroidetes 0.46808510638297873 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.900709219858156 tuf 1.0 - 0.8368794326241135 - 1.0 ko:K02358 0.9290780141843972 - 0.9290780141843972 - 0.9290780141843972 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9290780141843972 - 0.9290780141843972 - 1.0 - 0.9645390070921985 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.9290780141843972 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1557250 0 0 0 0 0 0 0 0 0 0 1060948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)AVDAGAASAR MGYG000002854_00976 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Peptostreptococcaceae|g__Peptacetobacter|s__Peptacetobacter sp900539645|m__MGYG000002854 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,22HEI@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5676261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)AVETGADAAGR MGYG000000249_01483;MGYG000004799_00497;MGYG000001379_02073;MGYG000000268_01898;MGYG000002596_02056 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1246483 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)AVFYGK MGYG000000095_02180 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__GCA-900066755|s__GCA-900066755 sp902363085|m__MGYG000000095 1.0 COG1063@1|root,COG1063@2|Bacteria,1UUV0@1239|Firmicutes,25MAN@186801|Clostridia,3Y1TA@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Alcohol dehydrogenase GroES-like domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 4022608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)DAATTIIPLDK MGYG000002560_04324 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp902388365|m__MGYG000002560 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)DDDFRK MGYG000004006_01512 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp000434235|m__MGYG000004006 1.0 COG1834@1|root,COG1834@2|Bacteria,4NFQ7@976|Bacteroidetes,2FNG1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 COG NOG25454 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 548210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)DLEGYLK MGYG000001255_00113;MGYG000001300_00595 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,3WJGA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 1754028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)DLGALQNR MGYG000002934_00200 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Caproiciproducens|s__Caproiciproducens sp900546895|m__MGYG000002934 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 hag 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 6047675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4544998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)EDNPWEQLK MGYG000002040_01384;MGYG000002272_02217;MGYG000001255_00085;MGYG000000195_02259 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3WGII@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 IJM 1.0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Ribosome;Metabolic pathways;Biosynthesis of secondary metabolites;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1063015 0 0 0 0 1270526 0 0 0 0 1095481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518908 0 0 0 0 429000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)ENMQTAESR MGYG000000187_02577 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,25VSN@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)ENTQSAESR MGYG000004271_01770 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1238979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)EVVKKPLKITETVLR MGYG000000271_00472 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 carboxylase 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)FIVTDSFLYK MGYG000001496_03152;MGYG000001954_02140;MGYG000001607_02072;MGYG000000249_01522;MGYG000000179_02579;MGYG000000392_01607;MGYG000000146_01010;MGYG000004779_01269;MGYG000000036_00973;MGYG000002279_01040;MGYG000002004_00639;MGYG000000268_01541;MGYG000000038_01608;MGYG000001311_01191;MGYG000001564_02820;MGYG000002829_01933;MGYG000000198_05065;MGYG000001379_01314;MGYG000002912_00827;MGYG000001310_00117;MGYG000000175_03076;MGYG000000402_01136;MGYG000001531_00350;MGYG000000258_01863;MGYG000004087_01471;MGYG000002772_01870 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 0.8076923076923077 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 108547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189478 0 0 0 0 0 0 0 364523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308923 0 0 0 0 360653 0 0 235917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1700420 0 0 0 0 113412 -A(Ala->Ser)FVAGADIGEMSTLTK MGYG000002156_02025;MGYG000002794_01606 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,4BXEG@830|Butyrivibrio 1.0 186801|Clostridia 1.0 I 1.0 Enoyl-CoA hydratase/isomerase 1.0 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1298181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)GAFKDEIVPVEVK MGYG000000233_02446 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,4BWBU@830|Butyrivibrio 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 2918301 0 0 0 0 2797022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2907434 0 4213936 0 0 0 0 0 3798189 0 0 5018977 0 0 0 0 0 0 0 0 0 0 5156824 0 0 0 0 4289681 0 2680681 0 0 0 0 0 3050874 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2144148 1332541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3534979 0 0 0 0 0 0 0 0 0 0 0 3193628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 685216 -A(Ala->Ser)GAFKDEIVPVEVKK MGYG000000233_02446 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,4BWBU@830|Butyrivibrio 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 156132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 533745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)GDTITVAYR MGYG000001306_03854;MGYG000004479_03019;MGYG000004797_00028;MGYG000000042_00899;MGYG000001599_02656;MGYG000003693_02594;MGYG000000243_01801;MGYG000002935_00735;MGYG000001783_01702;MGYG000000273_02944;MGYG000000781_00438;MGYG000001364_03460;MGYG000002478_00167;MGYG000002560_01858;MGYG000003498_00929;MGYG000001925_02300;MGYG000000043_02305;MGYG000003363_03253 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,2FSHU@200643|Bacteroidia,4AQXS@815|Bacteroidaceae 0.9444444444444444 976|Bacteroidetes 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 359916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1125145 1259497 0 0 807821 0 0 0 0 0 0 0 704863 0 0 0 925441 0 0 0 0 0 751240 0 0 0 0 0 0 0 0 1429235 0 0 0 0 -A(Ala->Ser)GEVPEAIR MGYG000001564_01916;MGYG000000087_01006;MGYG000000909_01230;MGYG000001619_00817;MGYG000001199_01751;MGYG000000194_02265;MGYG000000198_04904;MGYG000001688_04193;MGYG000000274_01720;MGYG000000205_02187 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,21YA9@1506553|Lachnoclostridium 0.8 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5127979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)GILNPVTK MGYG000000031_00355 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066205|m__MGYG000000031 1.0 COG2055@1|root,COG2055@2|Bacteria 1.0 2|Bacteria 1.0 C 1.0 Belongs to the LDH2 MDH2 oxidoreductase family 1.0 mdh 1.0 - 1.0 1.1.1.350 1.0 ko:K00073 1.0 ko00230,ko01120,map00230,map01120 1.0 - 1.0 R02935,R02936 1.0 RC00169 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ldh_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ureidoglycolate dehydrogenase (NAD(+)). - Involved in catabolism of purines.-!-The enzyme from the bacterium Escherichia coli is specific for NAD(+). cf. EC 1.1.1.154. (S)-ureidoglycolate + NAD(+) = H(+) + N-carbamoyl-2-oxoglycine + NADH. 1.0 1.0 1.0 1.0 Purine metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1771900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)GMGYC(Carbamidomethyl)GAK MGYG000004769_00915 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H2GU@909932|Negativicutes 1.0 909932|Negativicutes 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1590811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)GYWHLFR MGYG000003355_02242 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnoclostridium|s__Lachnoclostridium phytofermentans_A|m__MGYG000003355 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,21YPK@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 59695 0 0 0 45323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7551002 0 0 0 451356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 638328 0 0 0 0 0 0 0 -A(Ala->Ser)HILTGLPDTYGR MGYG000000479_01151 genome d__Bacteria|p__Spirochaetota|c__Spirochaetia|o__Treponematales|f__Treponemataceae|g__Treponema_D|s__Treponema_D sp900541995|m__MGYG000000479 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,268DX@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate formate lyase-like 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 763471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)IDDNILNIYK MGYG000002281_03314;MGYG000000196_02520;MGYG000001345_00571 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,4AMRT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 GK 1.0 Psort location Cytoplasmic, score 9.26 1.0 glk 1.0 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Neomycin, kanamycin and gentamicin biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 1265940 1187177 0 0 0 0 0 0 0 1301350 0 0 0 0 0 0 1151673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 840396 0 0 0 0 0 0 0 0 0 0 285345 0 0 0 0 0 0 479793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)IDINSLK MGYG000000236_02872 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,2FS3I@200643|Bacteroidia,4AM76@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly 1.0 rplM 1.0 - 1.0 - 1.0 ko:K02871 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2273938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)IDPVNDDLVVLNNR MGYG000001552_00916 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Marinifilaceae|g__Butyricimonas|s__Butyricimonas synergistica|m__MGYG000001552 1.0 COG3391@1|root,COG3391@2|Bacteria,4NJJN@976|Bacteroidetes,2FNI0@200643|Bacteroidia,22Z3Y@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 amine dehydrogenase activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1731201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632592 0 0 0 0 0 0 0 -A(Ala->Ser)IEAVDEC(Carbamidomethyl)VGK MGYG000000164_00796;MGYG000000255_02926;MGYG000000038_02188;MGYG000000233_02244;MGYG000000205_01016;MGYG000004799_00701;MGYG000001602_01797;MGYG000002279_00560;MGYG000000146_00360;MGYG000002992_00161;MGYG000001315_01695 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,27V4Y@189330|Dorea 0.45454545454545453 186801|Clostridia 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 - 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Metalloenzyme,PglZ,Phosphodiest,iPGM_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)ILDEATDPWGIK MGYG000003589_00770;MGYG000002182_00653;MGYG000002993_00293;MGYG000002926_00988;MGYG000002707_00629;MGYG000000223_01135;MGYG000004285_00398;MGYG000002485_01701;MGYG000001008_02199;MGYG000000380_00607 domain d__Bacteria 1.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,2N6P2@216572|Oscillospiraceae 0.3 186801|Clostridia 0.7 O 1.0 prohibitin homologues 0.4 qmcA 0.7 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Band_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 147025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 922840 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)KGKPIVNSADAGDR MGYG000003821_01555;MGYG000001338_02424;MGYG000002966_01692;MGYG000004785_01065;MGYG000000184_00686;MGYG000000200_00066;MGYG000002312_01594;MGYG000000213_00152 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3XZQ5@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 8.87 1.0 acsE 1.0 - 1.0 2.1.1.258 1.0 ko:K15023 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R02289,R10243 1.0 RC00004,RC00113,RC01144,RC02871,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pterin_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the N(5) group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein.-!-Involved, together with EC 1.2.7.4 and EC 2.3.1.169, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea. (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein] = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563249 0 0 0 0 927022 0 0 0 552009 0 0 0 0 0 0 0 620371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)KVDAAIDTK MGYG000001780_02426 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__|m__MGYG000001780 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1561372 0 743488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)LDNVTVSTITSHK MGYG000001370_00939 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fluxus|m__MGYG000001370 1.0 COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,2FMC2@200643|Bacteroidia,4AM54@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 9.97 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1309750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)LEEAGAEVEVK MGYG000002514_01947;MGYG000003539_00331;MGYG000002506_03692;MGYG000002323_03990;MGYG000002415_01567;MGYG000002507_00340 domain d__Bacteria 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria 0.3333333333333333 1236|Gammaproteobacteria 0.8333333333333334 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 0.8333333333333334 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)LEEVVVVGYATVK MGYG000000236_02987 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 801285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)LNEVVVIGYGR MGYG000002960_00779 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900555035|m__MGYG000002960 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 susC 1.0 - 1.0 - 1.0 ko:K21573 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14.6.1 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 751341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)LREEDVEFK MGYG000000045_02624 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,3XYKH@572511|Blautia 1.0 186801|Clostridia 1.0 L 1.0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity 1.0 mutS2 1.0 - 1.0 - 1.0 ko:K07456 1.0 ko03430,map03430 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03400 1.0 - 1.0 - 1.0 - 1.0 MutS_III,MutS_V,Smr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Mismatch repair 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 965863 0 0 0 0 504419 0 0 0 0 621109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312365 0 0 0 0 531991 0 0 0 0 629055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104750 0 0 0 0 0 0 0 0 0 204461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)LTEEEAK MGYG000000099_02570 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7285775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)LVAAGPKL MGYG000003535_01089;MGYG000001306_02577;MGYG000004479_02615;MGYG000003521_00688;MGYG000003693_02275;MGYG000002540_00741;MGYG000004824_00239;MGYG000001164_02313;MGYG000002455_01424;MGYG000004495_01226;MGYG000000273_00474;MGYG000003282_01713;MGYG000004763_01642;MGYG000003363_00033;MGYG000000415_02204;MGYG000001345_04617;MGYG000000451_00938;MGYG000000196_01785;MGYG000002549_03009;MGYG000001655_03297;MGYG000001551_02111;MGYG000000781_01597;MGYG000003681_02208;MGYG000001346_02112;MGYG000002506_03025;MGYG000000174_04897;MGYG000001599_00077;MGYG000003546_01574;MGYG000000043_00605;MGYG000004757_00433;MGYG000001604_00090;MGYG000003172_00938;MGYG000003252_01528 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,4AMYK@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 0.9696969696969697 H 0.9696969696969697 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 0.9696969696969697 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 0.9696969696969697 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2633387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2526929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)NDFSNTTR MGYG000003363_02700 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900766195|m__MGYG000003363 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1129287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)NLDNVSENTSSAESR MGYG000000271_01499 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 883455 4167058 0 3148307 988994 0 1639163 615479 1237367 0 0 0 928314 0 0 0 0 843585 0 685940 0 0 1366641 0 0 893297 0 1578858 0 0 0 2986234 0 0 0 0 4397092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 543914 0 0 0 0 0 0 0 0 0 0 0 0 0 396871 0 0 0 0 0 0 0 0 0 964592 0 0 0 0 0 0 0 181942 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)PIQVR MGYG000002105_00006 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__SFJ001|s__SFJ001 sp004555865|m__MGYG000002105 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4326623 0 0 0 9946870 0 0 0 6636017 0 0 0 0 0 0 0 0 0 0 0 7830273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)QAHIDAGAK MGYG000002999_00356;MGYG000002540_02142;MGYG000000375_01483;MGYG000001311_02933;MGYG000003012_02911;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000000205_02269;MGYG000003695_01114;MGYG000000145_03615;MGYG000002445_01920;MGYG000000193_03247;MGYG000002944_01470;MGYG000003110_00098;MGYG000004809_00788;MGYG000004799_00704;MGYG000000002_02120;MGYG000001065_01088;MGYG000002946_02881;MGYG000002966_00075;MGYG000002131_02428;MGYG000000242_02076;MGYG000003335_00316;MGYG000000233_00345;MGYG000001577_01888;MGYG000000099_02094;MGYG000003702_00925;MGYG000000252_01324;MGYG000000365_00999;MGYG000000301_01012;MGYG000004087_02290;MGYG000000312_01508;MGYG000001688_03910;MGYG000002972_00451;MGYG000000423_01499;MGYG000002857_01020;MGYG000002212_00259;MGYG000004296_01958;MGYG000000213_00374;MGYG000000281_02732;MGYG000000179_02084;MGYG000000142_01979;MGYG000000263_01341;MGYG000002095_00148;MGYG000004411_00321;MGYG000000806_01930;MGYG000001505_01467;MGYG000000212_01474;MGYG000001661_02632;MGYG000004785_01017;MGYG000000171_00850;MGYG000001757_00726;MGYG000001338_02547;MGYG000001602_01805;MGYG000003074_01265;MGYG000000133_02283;MGYG000002298_02410;MGYG000004246_01300;MGYG000001315_01699;MGYG000002035_01208 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.47540983606557374 186801|Clostridia 0.8852459016393442 C 0.7704918032786885 Psort location Cytoplasmic, score 0.47540983606557374 gap 0.9672131147540983 - 0.9672131147540983 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 595502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)QAHINAGAK MGYG000003457_01802;MGYG000000188_00829;MGYG000004740_01468;MGYG000002947_01132;MGYG000000325_00586;MGYG000000187_02264;MGYG000000262_01195;MGYG000004681_01193;MGYG000002775_01122;MGYG000000802_01543;MGYG000004707_01697;MGYG000001456.1_00715;MGYG000002278_02184;MGYG000002968_00328;MGYG000000562_01218;MGYG000000515_01608;MGYG000003274_01603;MGYG000002970_00369;MGYG000004317_00142;MGYG000001718_00619;MGYG000004396_00612;MGYG000001567_00998;MGYG000004593_01977;MGYG000000077_00219;MGYG000001334_01647 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CUJP@84998|Coriobacteriia 0.44 186801|Clostridia 0.48 C 0.76 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.56 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341180 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)QEALGMVETR MGYG000000212_01004;MGYG000003012_02042;MGYG000004733_01677;MGYG000000301_01355;MGYG000000268_01896;MGYG000000252_02290;MGYG000000201_01077;MGYG000004039_01859;MGYG000002966_00344;MGYG000000031_02920;MGYG000000171_01277;MGYG000000263_00749;MGYG000001615_02630;MGYG000000127_01924;MGYG000002298_00042;MGYG000004785_00406;MGYG000000806_00431;MGYG000002298_02777;MGYG000000142_01603;MGYG000000202_01544 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.75 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.8 - 1.0 - 1.0 - 1.0 - 0.95 - 1.0 - 1.0 - 1.0 - 1.0 - 0.95 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2971993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)QIEETTSDFDREK MGYG000000038_02089;MGYG000002992_01078;MGYG000002445_00865;MGYG000001367_02937;MGYG000001607_00737;MGYG000001688_01574;MGYG000001617_04641;MGYG000002202_00450;MGYG000002279_00394 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,21YIV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1725136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)QIETTTSDYDREK MGYG000004726_00851;MGYG000004464_01712 domain d__Bacteria 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2681F@186813|unclassified Clostridiales 0.5 186801|Clostridia 0.5 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 0.5 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1115889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1461608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)SFDAGQTTTGDLWGDEWK MGYG000003165_00389 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus|s__Coprococcus sp900548315|m__MGYG000003165 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)SFEQPVETR MGYG000004797_02944 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 1712730 0 0 0 3288098 2024107 0 0 0 0 0 0 3592472 0 0 3772479 0 1808986 0 0 0 1691208 1848017 2237149 0 0 0 1692671 0 0 0 0 0 0 0 1597570 1988733 0 4764298 0 0 0 2109437 1096940 3344070 0 0 0 0 0 4684446 4722516 0 2861626 0 1040071 1394713 0 0 1096797 1664614 874119 0 1059476 0 887109 0 0 0 0 0 0 0 1006881 3825095 0 1290839 0 0 0 2049821 1380004 1382506 0 0 0 0 0 2343270 1069038 0 1945508 0 2139539 746539 0 0 1168649 1522536 1031799 0 959195 0 1193034 0 0 0 0 0 0 0 1296685 1091314 0 0 0 0 0 0 0 0 0 0 0 0 0 959925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443182 0 0 0 0 0 0 0 0 0 0 1716392 0 0 0 3574882 1900320 1525768 0 0 0 0 0 4387458 1160387 0 2838245 0 3186372 1648230 0 0 1745022 2331393 1576024 0 2092280 0 2197634 0 0 0 0 0 0 0 1331366 2091640 0 -A(Ala->Ser)SGNDIVAPYADEFPGSTFVAGK MGYG000000236_00923 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AMNJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdh 1.0 GO:0005575,GO:0005623,GO:0009986,GO:0044464 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1475114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2028382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)SLDVATDPWGIK MGYG000002279_00846;MGYG000000133_02658;MGYG000004719_00917;MGYG000000650_01797;MGYG000002298_02982;MGYG000002992_00180;MGYG000002212_01684;MGYG000000038_02902;MGYG000000002_03269;MGYG000000301_01961;MGYG000004733_03198;MGYG000003684_05093 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3XZEQ@572511|Blautia 0.5 186801|Clostridia 1.0 O 1.0 SPFH Band 7 PHB domain protein 0.5833333333333334 qmcA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Band_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 698757 0 0 1248262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 805948 0 0 1022831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)SNIGQVAQFAAAGK MGYG000004482_01233;MGYG000002720_01300;MGYG000002753_00323;MGYG000002716_01693;MGYG000002042_01048;MGYG000003435_00255;MGYG000001616_01740;MGYG000002926_00914;MGYG000004628_00495;MGYG000000935_00193;MGYG000002794_00417;MGYG000002727_00774 domain d__Bacteria 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,2N72Y@216572|Oscillospiraceae 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 0.9166666666666666 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 495506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 800227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)STIFPEFVGHTFAVHDGR MGYG000002272_00455;MGYG000003899_00618;MGYG000004681_01721;MGYG000001300_02211;MGYG000002040_00974;MGYG000000195_02129;MGYG000000022_02036;MGYG000003166_00763;MGYG000002619_02382;MGYG000001627_01316;MGYG000002545_01136;MGYG000002274_00841;MGYG000002641_00984 domain d__Bacteria 1.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3WJ9F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA 1.0 rpsS 1.0 - 1.0 - 1.0 ko:K02965 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277621 0 0 0 0 0 0 0 0 0 394392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174353 0 0 0 0 150386 0 0 0 0 87154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73695 0 0 0 0 0 0 0 0 0 204881 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)TGANTANEALGNLYIK MGYG000000042_01472;MGYG000001599_00128 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2894609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3602285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)TGWAEEDGTWVYYNR MGYG000001531_03141;MGYG000000179_05046;MGYG000001493_03216;MGYG000001531_03157;MGYG000000198_04292;MGYG000001493_03204;MGYG000001531_03144;MGYG000001493_03219 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 0.875 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 418656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1281356 0 -A(Ala->Ser)TNVELIEAAC(Carbamidomethyl)GK MGYG000000038_01566 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena|m__MGYG000000038 1.0 COG0252@1|root,COG5275@1|root,COG0252@2|Bacteria,COG5275@2|Bacteria,1TQ9S@1239|Firmicutes,24A9Y@186801|Clostridia,27WDD@189330|Dorea 1.0 186801|Clostridia 1.0 EJ 1.0 Glycine/sarcosine/betaine reductase component B subunits 1.0 prdA 1.0 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114 1.0 1.21.4.1 1.0 ko:K10793 1.0 ko00330,map00330 1.0 - 1.0 R02825 1.0 RC00790 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 D-proline reductase. - A pyruvoyl- and L-selenocysteine-containing enzyme found in a number of Clostridial species.-!-The pyruvoyl group, located on the PrdA subunit, binds the substrate, while the selenocysteine residue, located on the PrdB subunit, attacks the alpha-C-atom of D-proline, leading to a reductive cleavage of the C-N-bond of the pyrrolidine ring and formation of a selenoether.-!-The selenoether is cleaved by a cysteine residue of PrdB, resulting in a mixed selenide-sulfide bridge, which is restored to its reduced state by another selenocysteine protein, PrdC.-!-5-aminopentanoate is released from PrdA by hydrolysis, regenerating the pyruvoyl moiety.-!-The resulting mixed selenide-sulfide bridge in PrdC is reduced by NADH.-!-Formerly EC 1.4.1.6 and EC 1.4.4.1. 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine = [PrdC protein]-L-selenocysteine/L-cysteine + D-proline. 1.0 1.0 1.0 1.0 Arginine and proline metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 2521800 3540059 2447957 0 0 0 0 0 0 0 3926898 0 0 0 0 0 0 3067481 0 0 0 0 0 2652558 0 0 2877909 0 0 0 0 0 3186725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3563000 0 0 0 0 0 3254860 0 0 573157 0 4289258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2832581 4761946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3767368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3621202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)TVVTGVEMFR MGYG000003868_01133;MGYG000003868_01166;MGYG000004769_00412;MGYG000004769_00437 genus d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4H22P@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 205823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723119 0 0 793274 0 0 0 0 0 744120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)VDPSVAEEANK MGYG000000196_00570 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 988009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)VGEAIVEATK MGYG000000013_01224;MGYG000002549_02739;MGYG000002281_01909;MGYG000000138_00869;MGYG000000044_00323;MGYG000004876_02584;MGYG000002455_00199;MGYG000004185_02169 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 0.75 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2081411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)VGELLQNQYR MGYG000002528_01103;MGYG000000142_00117;MGYG000004140_01870;MGYG000003063_00668;MGYG000002445_01331;MGYG000000179_00950;MGYG000000145_02776;MGYG000001814_01581;MGYG000004785_02035;MGYG000003694_02393;MGYG000000164_01118;MGYG000000271_03641;MGYG000000198_01125;MGYG000002148_02227;MGYG000000193_02077;MGYG000000909_01259;MGYG000000217_01477;MGYG000000359_01966;MGYG000000262_00025;MGYG000002492_00339;MGYG000002517_00197;MGYG000001707_01471;MGYG000002670_00359;MGYG000003422_00869;MGYG000000028_00231;MGYG000004697_01015;MGYG000000484_02056;MGYG000003427_01334;MGYG000000139_00682;MGYG000001338_03384;MGYG000001683_01328;MGYG000001619_01910;MGYG000000233_00817;MGYG000000242_00290;MGYG000000002_03604;MGYG000000127_00618;MGYG000002304_02205;MGYG000004414_00350;MGYG000004735_00902;MGYG000000150_02012;MGYG000002417_01250;MGYG000000172_05471;MGYG000003355_03484;MGYG000000018_00459;MGYG000000281_02099;MGYG000004271_02226;MGYG000000249_00042;MGYG000000398_01656;MGYG000003486_01060;MGYG000001493_02698;MGYG000001564_03092;MGYG000003684_05127;MGYG000002289_02137;MGYG000000251_01869;MGYG000004680_00150;MGYG000001311_05232;MGYG000002290_01341;MGYG000001615_01700;MGYG000000489_01681;MGYG000000278_00899;MGYG000001319_01769;MGYG000000690_00038;MGYG000002052_00237;MGYG000001310_01990;MGYG000004431_01386;MGYG000000213_01890 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia 0.2727272727272727 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 - 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 1673084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1178907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)VIELAGIK MGYG000001315_01353;MGYG000004733_00985;MGYG000000201_02098;MGYG000000252_01802;MGYG000001423_01155;MGYG000000301_00177;MGYG000001338_02790;MGYG000001689_02303;MGYG000000031_02249;MGYG000000142_02050;MGYG000000133_00062;MGYG000000002_00865;MGYG000002966_02558;MGYG000000212_03064;MGYG000000213_00197;MGYG000004296_00406;MGYG000000184_01189;MGYG000000050_01189;MGYG000000216_02346;MGYG000002298_00345;MGYG000000251_01814 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.9047619047619048 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1842939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1020905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)VIELAGLK MGYG000001315_01353;MGYG000000133_00062;MGYG000001338_02790;MGYG000000142_02050 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.75 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1802984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)VIEMAGIK MGYG000000038_01593;MGYG000004842_00293;MGYG000000206_01051;MGYG000001374_01179;MGYG000000146_01034;MGYG000000164_02747;MGYG000002279_01055;MGYG000001303_01198;MGYG000001310_00104 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,27V4S@189330|Dorea 0.5555555555555556 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1359013 0 0 0 0 0 0 0 0 0 0 631377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756527 0 0 951856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)VLDSYAGK MGYG000000039_02623;MGYG000000195_01938;MGYG000000022_00316 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,3WJGA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1591982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 948727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)VSETVDIMDAK MGYG000002945_00739 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus massiliensis|m__MGYG000002945 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,27IGM@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 7081442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)VVELAGIK MGYG000000242_01806;MGYG000000359_02324;MGYG000003012_01983;MGYG000000413_00080;MGYG000000141_02164 domain d__Bacteria 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,21YA9@1506553|Lachnoclostridium 0.2 186801|Clostridia 0.8 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 0.8 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1070403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)WAPQNWDKYDELIK MGYG000000404_01511 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA11774|s__UBA11774 sp003507655|m__MGYG000000404 1.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Family 5 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 2938480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)YADMMEPIYK MGYG000004479_01906;MGYG000001783_02108;MGYG000003693_03030;MGYG000001306_00956 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2825@1|root,COG2825@2|Bacteria,4NWPA@976|Bacteroidetes,2G3DE@200643|Bacteroidia,4AWDW@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 M 1.0 Membrane 0.75 - 0.75 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1123922 0 0 0 0 0 0 0 0 0 0 0 0 0 1319706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1602278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525139 0 510877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)YALLDELKK MGYG000001607_01352 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_B|s__Dorea_B phocaeensis|m__MGYG000001607 1.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,27V62@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) 1.0 proS 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 6.1.1.15 1.0 ko:K01881 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03661 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,ProRS-C_1,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 proline--tRNA ligase. prolyl-tRNA synthetase. - ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 511262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)YDGQYVQTR MGYG000002293_00403 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG1629@1|root,COG4771@2|Bacteria,4NIXB@976|Bacteroidetes,2FNC3@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 beta-fructofuranosidase activity 1.0 scrL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_32C,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3016255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)YILAPDGLK MGYG000004869_03323 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lactonifactor|s__Lactonifactor sp009677585|m__MGYG000004869 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3XZ12@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1120084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)YIPGIGHNLQEHSVVLIR MGYG000002113_00819 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Anaerovibrio|s__Anaerovibrio sp900548165|m__MGYG000002113 1.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4H4CG@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit 1.0 rpsL 1.0 - 1.0 - 1.0 ko:K02950 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S12_S23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 804966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)YSPWSSK MGYG000002438_00414 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG3630@1|root,COG3630@2|Bacteria,4NIHN@976|Bacteroidetes,2FMSV@200643|Bacteroidia,22W1S@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxaloacetate decarboxylase, gamma chain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 LTD,OAD_gamma 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1222051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)YTPQEISAMILQK MGYG000001733_01226 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550615|m__MGYG000001733 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,2N6EU@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 O 1.0 MreB/Mbl protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 771973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Ser)YTVETNR MGYG000000196_04774 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia,4AMCZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 895898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656174 0 0 -A(Ala->Thr)AAEAYFGK MGYG000000196_01844;MGYG000000029_02657;MGYG000003312_02145;MGYG000001345_04496 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1399864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)AAESYLSK MGYG000003367_01391;MGYG000004876_01285 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1911619 0 0 2474203 0 1143339 0 2299759 0 0 0 0 2648421 3284344 0 0 2354301 0 0 0 0 0 0 0 0 0 0 0 0 4434269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6316477 0 3629733 0 3390012 4536151 3727103 4226813 0 2991729 0 0 0 0 3814793 0 1913448 0 0 0 0 0 0 0 0 0 0 0 2650366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2050119 0 0 0 0 0 0 1724844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3024391 0 0 0 2791338 0 0 0 2327616 -A(Ala->Thr)AAEVTPEEKKEE MGYG000000271_02066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,27IMH@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Fibronectin type III-like domain 1.0 - 1.0 - 1.0 3.2.1.21 1.0 ko:K05349 1.0 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 1.0 - 1.0 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 1.0 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH3 1.0 - 1.0 Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C 1.0 - 1.0 GH3 1.0 GH3 1.0 GH3 1.0 beta-glucosidase. gentobiase. Wide specificity for beta-D-glucosides.-!-Some examples also hydrolyze one or more of the following: beta-D- galactosides, alpha-L-arabinosides, beta-D-xylosides and beta-D- fucosides. Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose. 1.0 1.0 1.0 1.0 Phenylpropanoid biosynthesis;Metabolic pathways;Starch and sucrose metabolism;Cyanoamino acid metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 97236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2469811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)AAQTDNVHRPFYPMLIFR MGYG000002469_00856 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium breve|m__MGYG000002469 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)AASESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3420558 0 2230228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5931805 0 0 8532388 0 0 0 6360862 0 0 0 0 0 0 0 8717928 0 0 0 0 0 0 0 0 0 0 0 0 1623647 0 0 1527232 0 0 0 0 2160865 0 0 0 0 1799405 0 0 0 0 0 0 0 0 6702418 0 0 0 0 0 0 0 0 0 0 0 0 1780388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521019 0 0 0 0 0 0 0 0 0 848364 0 0 727932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660281 699352 0 -A(Ala->Thr)AASESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 871387 0 0 0 0 0 0 0 0 0 0 0 0 698258 0 0 0 0 0 0 0 0 0 0 0 0 0 811392 888669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)AASESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 1191884 0 0 0 0 0 0 0 1021672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 833801 0 0 0 0 948492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)AEAYFLLAEAK MGYG000002478_01404;MGYG000004797_04332 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1735704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)AEIPEAIR MGYG000000136_02061;MGYG000002670_00403;MGYG000001315_01353;MGYG000002234_01458;MGYG000004733_00985;MGYG000003891_01006;MGYG000000252_01802;MGYG000000280_01284;MGYG000000031_02249;MGYG000000142_02050;MGYG000004630_00952;MGYG000002492_00392;MGYG000000135_01188;MGYG000000690_01576;MGYG000000028_01605;MGYG000004689_01598;MGYG000002517_02856;MGYG000000002_00865;MGYG000002966_02558;MGYG000001186_01095;MGYG000000213_00197;MGYG000004296_00406;MGYG000000806_01299;MGYG000002278_02309;MGYG000000050_01189;MGYG000002298_00345;MGYG000000193_02113;MGYG000000201_02098;MGYG000000301_00177;MGYG000004879_01580;MGYG000001338_02790;MGYG000002528_01856;MGYG000000164_02747;MGYG000001689_02303;MGYG000000562_01931;MGYG000000133_00062;MGYG000000212_03064;MGYG000000184_01189;MGYG000003694_02445;MGYG000000216_02346;MGYG000000251_01814;MGYG000001637_00014;MGYG000000187_01741 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.46511627906976744 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2171422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)AGVIVAC(Carbamidomethyl)DTNVPTDRFDGK MGYG000002492_00017 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Phosphotransferase System 1.0 fruA 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 GGDEF,PTS_EIIA_2,PTS_EIIC,PTS_IIB,Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS);Metabolic pathways;Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2599405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2673789 0 0 0 0 2580781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)AGVIVAC(Carbamidomethyl)DTNVPTDRFDGKK MGYG000002492_00017 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Phosphotransferase System 1.0 fruA 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 GGDEF,PTS_EIIA_2,PTS_EIIC,PTS_IIB,Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS);Metabolic pathways;Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193983 0 0 0 0 349274 0 0 314691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 377303 0 0 0 0 625789 0 0 2758920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3495911 0 0 0 0 2961558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155871 -A(Ala->Thr)ANVSLVGYEK MGYG000004087_00692;MGYG000001564_03645;MGYG000000205_00403;MGYG000000198_03144 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 0.75 186801|Clostridia 0.75 CQ 1.0 PFAM microcompartments protein 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 9341003 0 0 0 0 0 0 0 0 0 0 0 15318127 0 0 0 0 0 0 0 12321948 0 0 0 0 0 14527780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25466540 0 0 0 0 17282713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81291414 0 0 0 0 0 0 37020253 0 0 0 0 0 0 0 0 0 0 0 0 29458752 0 32629206 0 0 0 0 0 0 0 31240089 0 0 55223525 -A(Ala->Thr)APHLDGSYAAFGK MGYG000000133_02803;MGYG000000301_01800 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides 1.0 ppiB 1.0 - 1.0 5.2.1.8 1.0 ko:K03768 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Pro_isomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1211434 0 0 0 0 0 0 0 0 0 0 0 1473779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)AVAGIK MGYG000004317_00074 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp900316325|m__MGYG000004317 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,268N0@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)AVVGDTVGDPFK MGYG000003510_01564;MGYG000002964_00576;MGYG000002036_00419;MGYG000001500_00249;MGYG000002212_02487;MGYG000002673_01165;MGYG000001502_01055;MGYG000000179_01304;MGYG000000198_01375;MGYG000002727_01191;MGYG000001576_02602;MGYG000002953_01954;MGYG000002229_02459;MGYG000001616_01732;MGYG000003589_01348 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,2N6F3@216572|Oscillospiraceae 0.5333333333333333 186801|Clostridia 1.0 C 1.0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane 0.8666666666666667 hppA 1.0 - 1.0 3.6.1.1 1.0 ko:K15987 1.0 ko00190,map00190 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 3.A.10.1 1.0 - 1.0 - 1.0 H_PPase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 inorganic diphosphatase. pyrophosphate phosphohydrolase. Specificity varies with the source and with the activating metal ion.-!-The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9. cf. EC 7.1.3.1. diphosphate + H2O = H(+) + 2 phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1187103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)DAPVAGK MGYG000002506_00491;MGYG000002323_02391;MGYG000000093_04195 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2376@1|root,COG2376@2|Bacteria,1MVSR@1224|Proteobacteria,1RNRQ@1236|Gammaproteobacteria,3XP0J@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 1.0 G 1.0 Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)- dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP. Binds covalently dihydroxyacetone in hemiaminal linkage. DhaK acts also as corepressor of the transcription activator DhaR by binding to the sensor domain of DhaR. In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity. In the absence of dihydroxyacetone, DhaL-ADP is converted by the PTS to DhaL-ATP, which does not bind to DhaR 0.6666666666666666 dhaK 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 1.0 2.7.1.121 1.0 ko:K05878 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 1.0 Dak1,Dak2 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 82293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258575 0 0 0 0 0 0 0 0 118676 0 143092 0 0 0 0 0 0 0 0 0 598149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541750 421163 551141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1354999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1582372 0 0 0 0 0 0 0 0 2967112 2370534 1189265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)EGVDLSGDKMAMQR MGYG000000153_02121 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-45|s__CAG-45 sp000438375|m__MGYG000000153 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1341226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)GDAAAALK MGYG000002478_02340 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9258451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)GDDAAGLSISEK MGYG000001309_02256;MGYG000004879_00388;MGYG000001309_02255;MGYG000003116_00184;MGYG000004317_00523;MGYG000003142_01387;MGYG000003273_00970;MGYG000003142_01386 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,36ED6@31979|Clostridiaceae 0.75 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 fliC 0.75 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_IN,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 1733369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1561404 0 3917645 0 0 0 0 4696930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)GGSIISSQK MGYG000001364_02798;MGYG000000243_01847;MGYG000001783_02406 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1586009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)GLDKIISQIK MGYG000000198_04354 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG1390@1|root,COG1390@2|Bacteria,1VDHZ@1239|Firmicutes,24H5N@186801|Clostridia,220QV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane 1.0 atpE 1.0 - 1.0 - 1.0 ko:K02121 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 vATP-synt_E 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2224812 0 0 0 0 2654682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3708117 0 0 0 0 0 0 3457662 0 0 0 0 132028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365106 0 0 0 0 2698339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)GMIGLAK MGYG000000074_00315;MGYG000004797_02999;MGYG000000243_00655;MGYG000004763_02028;MGYG000002438_03088 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,2FNB4@200643|Bacteroidia,4ANUZ@815|Bacteroidaceae 0.6 976|Bacteroidetes 1.0 IQ 1.0 with different specificities (related to short-chain alcohol 0.6 fabG 1.0 - 1.0 1.1.1.100 1.0 ko:K00059 1.0 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 1.0 M00083,M00572 1.0 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-oxoacyl-[acyl-carrier-protein] reductase. - Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates. a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH. 1.0 1.0 1.0 1.0 Biotin metabolism;Fatty acid metabolism;Fatty acid biosynthesis;Biosynthesis of unsaturated fatty acids;Metabolic pathways;Prodigiosin biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)GTVTMDVTK MGYG000000139_00679;MGYG000002992_01641;MGYG000000217_01483;MGYG000000095_03286;MGYG000002963_02025;MGYG000001698_00708;MGYG000004839_01328;MGYG000000171_01515;MGYG000003694_02390;MGYG000000201_02339;MGYG000004762_01114;MGYG000000050_01365;MGYG000004733_01323;MGYG000001027_00236;MGYG000000179_05050;MGYG000003695_01274;MGYG000000152_04608;MGYG000000242_00769;MGYG000000119_02509;MGYG000001571_03428;MGYG000000076_03547;MGYG000002966_01277;MGYG000000251_00050;MGYG000000249_00046;MGYG000004296_01660;MGYG000001338_03534;MGYG000000387_00298;MGYG000000154_02173;MGYG000001970_02771;MGYG000000212_02414;MGYG000002552_01596;MGYG000001622_01986;MGYG000003425_04472;MGYG000001186_01608;MGYG000004604_00078;MGYG000001714_01227;MGYG000000087_02073;MGYG000004735_02574;MGYG000000268_01636;MGYG000002445_02953;MGYG000002772_00853;MGYG000001303_01960;MGYG000004630_01085;MGYG000001607_01030;MGYG000001687_02063;MGYG000001315_01189;MGYG000002517_00192;MGYG000002286_02461;MGYG000004718_01623;MGYG000000146_01144;MGYG000001748_00537;MGYG000002202_02038;MGYG000000271_03296;MGYG000000164_01129;MGYG000000031_00709;MGYG000000153_01114;MGYG000002845_01899;MGYG000000136_02022;MGYG000001689_01643;MGYG000002170_01019;MGYG000001065_00817;MGYG000003335_00786;MGYG000002393_01693;MGYG000000278_00573;MGYG000001439_02403;MGYG000002492_00336;MGYG000004519_00684;MGYG000001374_02225;MGYG000001319_01772;MGYG000002298_02666;MGYG000000287_00086;MGYG000000078_01689;MGYG000003149_00722;MGYG000002670_00356;MGYG000000002_03534;MGYG000000198_05828;MGYG000000364_02037;MGYG000001660_01137;MGYG000002596_02351;MGYG000001683_01776;MGYG000004747_01843;MGYG000000080_02021;MGYG000003702_00729;MGYG000002279_01914;MGYG000001688_00640;MGYG000002312_03039;MGYG000000142_01261;MGYG000000562_01874;MGYG000002836_02018;MGYG000000187_02021;MGYG000002985_00771;MGYG000000489_01684;MGYG000002835_01623;MGYG000000018_02173;MGYG000000140_01578;MGYG000000205_00361;MGYG000000274_00236;MGYG000000200_03209;MGYG000001141_02451;MGYG000001379_00716;MGYG000003215_01171;MGYG000000133_01992;MGYG000004087_00328;MGYG000000252_00576 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 0.36538461538461536 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 1474687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3241875 0 0 0 0 0 0 0 0 0 743243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1102867 0 0 0 0 0 0 0 0 525223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)HGLDKDFK MGYG000002281_00379;MGYG000001313_01603;MGYG000001783_00231;MGYG000003693_02561;MGYG000001378_00884;MGYG000003681_01596;MGYG000000196_04607;MGYG000004797_00652;MGYG000004876_02961;MGYG000001787_00293 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,2FN9P@200643|Bacteroidia,4AN2N@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 xylA 1.0 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 1.0 5.3.1.5 1.0 ko:K01805 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 - 1.0 R00878,R01432 1.0 RC00376,RC00516 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 xylose isomerase. D-xylose ketol-isomerase. Contains two divalent metal ions, preferably magnesium, located at different metal-binding sites within the active site.-!-The enzyme catalyzes the interconversion of aldose and ketose sugars with broad substrate specificity.-!-The enzyme binds the closed form of its sugar substrate (in the case of xylose and glucose, only the alpha anomer) and catalyzes ring opening to generate a form of open-chain conformation that is coordinated to one of the metal sites.-!-Isomerization proceeds via a hydride-shift mechanism. alpha-D-xylose = alpha-D-xylulofuranose. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2333533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)IDMIGMPGMK MGYG000000164_01756;MGYG000002279_02008;MGYG000001315_01946;MGYG000002992_01235;MGYG000000038_01290;MGYG000002945_01470;MGYG000001687_01112 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,27VFG@189330|Dorea 0.8571428571428571 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 888155 0 0 894179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)IGQFQNTQFQLADMATK MGYG000000204_00801 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eubacterium_G|s__Eubacterium_G sp000435815|m__MGYG000000204 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1105048 0 0 0 0 0 0 0 0 -A(Ala->Thr)IIDSLHEFNPMMGHR MGYG000000140_01464;MGYG000001687_00537;MGYG000004558_03187;MGYG000004735_00207;MGYG000000249_01089;MGYG000000728_00587;MGYG000000164_00358;MGYG000001607_01964;MGYG000000159_02392;MGYG000001439_01567;MGYG000001374_00487;MGYG000001310_01399;MGYG000001637_01169;MGYG000004296_00104 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.6428571428571429 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8571428571428571 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)IIEAIK MGYG000002966_01860 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900551075|m__MGYG000002966 1.0 COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 COG NOG14451 non supervised orthologous group 1.0 - 1.0 - 1.0 2.7.4.25 1.0 ko:K00945 1.0 ko00240,ko01100,map00240,map01100 1.0 M00052 1.0 R00158,R00512,R01665 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 (d)CMP kinase. deoxycytidylate kinase. The prokaryotic cytidine monophosphate kinase specifically phosphorylates CMP (or dCMP), using ATP as the preferred phosphoryl donor.-!-Unlike EC 2.7.4.14, a eukaryotic enzyme that phosphorylates UMP and CMP with similar efficiency, the prokaryotic enzyme phosphorylates UMP with very low rates, and this function is catalyzed in prokaryotes by EC 2.7.4.22.-!-The enzyme phosphorylates dCMP nearly as well as it does CMP. (1) ATP + CMP = ADP + CDP. (2) ATP + dCMP = ADP + dCDP. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 957389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)ILDALK MGYG000000255_00877;MGYG000000233_02976 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,21XUU@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 COG COG1775 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit, BcrC BadD HgdB 1.0 hgdB 1.0 - 1.0 1.3.7.8,4.2.1.167 1.0 ko:K04112,ko:K20904 1.0 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 1.0 M00541 1.0 R02451 1.0 RC00002,RC01839 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HGD-D 1.0 - 1.0 - 1.0 - 1.0 - 1.0 benzoyl-CoA reductase. | (R)-2-hydroxyglutaryl-CoA dehydratase. - Inactive toward aromatic acids that are not CoA esters but will also catalyze the reaction: NH3 + acceptor + 2 ADP + 2 phosphate = hydroxylamine + reduced acceptor + 2 ATP + H2O.-!-In the presence of reduced acceptor, but in the absence of oxidizable substrate, the enzyme catalyzes the hydrolysis of ATP to ADP plus phosphate.-!-Formerly EC 1.3.99.15. | The enzymes from the bacteria Acidaminococcus fermentans and Clostridium symbiosum are involved in the fermentation of L-glutamate.-!-The enzyme contains [4Fe-4S] clusters, FMNH2 and riboflavin.-!-It must be activated by a an activator protein.-!-Once activated, it can catalyze many turnovers. 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized 2[4Fe-4S]- [ferredoxin] + 2 phosphate = 2 ATP + benzoyl-CoA + 2 H2O + reduced 2[4Fe- 4S]-[ferredoxin]. | (R)-2-hydroxyglutaryl-CoA = (2E)-glutaconyl-CoA + H2O. 1.0 1.0 1.0 1.0 Degradation of aromatic compounds;Metabolic pathways;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1576867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)ILEALK MGYG000001319_00393;MGYG000000089_01318 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,4BZXW@830|Butyrivibrio 0.5 186801|Clostridia 1.0 G 1.0 PTS HPr component phosphorylation site 0.5 - 0.5 - 1.0 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 1.0 - 1.0 - 0.5 PTS-HPr 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.5 0.5 0.5 0.5 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 968163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)KIDAAVDTK MGYG000004899_00435 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900555635|m__MGYG000004899 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)KLEAEGAEVNLK MGYG000000164_01127 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,27VNP@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 207809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117598 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)LAALNAGLK MGYG000000022_00458;MGYG000000039_00979;MGYG000000589_00366 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1719481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1336171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1996646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)LAANLKEGK MGYG000002545_01058 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_G|m__MGYG000002545 1.0 COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,3WIE3@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1014233 0 0 0 0 71512 0 0 0 0 65867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)LAIC(Carbamidomethyl)TVSDHIR MGYG000002507_00236;MGYG000002323_00590 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0813@1|root,COG0813@2|Bacteria,1MUW6@1224|Proteobacteria,1RMMA@1236|Gammaproteobacteria,3WWYQ@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Phosphorylase superfamily 1.0 deoD 1.0 GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 1.0 2.4.2.1 1.0 ko:K03784 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_1997,iB21_1397.B21_04226,iE2348C_1286.E2348C_4682,iEC042_1314.EC042_4881,iECABU_c1320.ECABU_c50190,iECBD_1354.ECBD_3636,iECB_1328.ECB_04260,iECD_1391.ECD_04260,iECED1_1282.ECED1_5255,iECIAI39_1322.ECIAI39_4916,iECNA114_1301.ECNA114_4626,iECO26_1355.ECO26_5590,iECOK1_1307.ECOK1_4950,iECP_1309.ECP_4768,iEcolC_1368.EcolC_3672,iLF82_1304.LF82_0467,iNRG857_1313.NRG857_22170,iPC815.YPO0440,iSFV_1184.SFV_4418,iSF_1195.SF4416,iSFxv_1172.SFxv_4809,iS_1188.S4687,iUMN146_1321.UM146_22680,iUMNK88_1353.UMNK88_5303,iUTI89_1310.UTI89_C5155,ic_1306.c5468 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Metabolic pathways;Nicotinate and nicotinamide metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1834418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)LGDLSEEEFEAHK MGYG000000133_00919 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) 1.0 galK 1.0 - 1.0 2.7.1.6 1.0 ko:K00849 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00554,M00632 1.0 R01092 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 galactokinase. - Part of the Leloir pathway for galactose metabolism.-!-The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine. alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+). 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 107132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212558 0 0 0 0 0 0 0 0 0 0 0 0 0 566086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1067229 0 0 0 0 0 0 0 764655 0 0 1430536 0 0 0 0 913390 0 0 0 0 0 0 0 0 0 0 0 0 0 1290476 0 0 0 0 688912 -A(Ala->Thr)LLHNMVVGVTDGYKK MGYG000004482_01002 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4|s__ER4 sp900546295|m__MGYG000004482 1.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,2N726@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center 1.0 rplF 1.0 - 1.0 - 1.0 ko:K02933 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 868997 0 0 0 0 0 0 0 444913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)LTLYGK MGYG000001346_01584 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1256@1|root,COG1256@2|Bacteria,4PKVX@976|Bacteroidetes,2G05N@200643|Bacteroidia,4AWF1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 bacterial-type flagellum assembly 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8322197 2618057 0 0 0 1557675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)MEPSR MGYG000000133_00153 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3XZ1Q@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 8.87 1.0 purB 1.0 - 1.0 4.3.2.2 1.0 ko:K01756 1.0 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 1.0 M00048,M00049 1.0 R01083,R04559 1.0 RC00379,RC00444,RC00445 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADSL_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 adenylosuccinate lyase. succino AMP-lyase. Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole. (1) N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate. (2) (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamide + fumarate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1600694 0 0 -A(Ala->Thr)MGQQITSDAC(Carbamidomethyl)THDNAEEK MGYG000001319_02248 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia,4BYAS@830|Butyrivibrio 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16689706 0 0 0 0 32194250 0 0 0 0 37061798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)NEAYLQGQLGNPK MGYG000002506_02522;MGYG000000235_01782;MGYG000002515_02771 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,3XMVJ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis 1.0 fbaA 1.0 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iZ_1308.Z4263 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1086185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 565107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)NELKADEER MGYG000002323_01056 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia sp000208585|m__MGYG000002323 1.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,3XM6A@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2957137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)NLIAQLTAPVR MGYG000001489_02989;MGYG000000003_02000;MGYG000000138_01885;MGYG000004658_00545;MGYG000000355_01595;MGYG000002033_00373;MGYG000004006_02257;MGYG000003701_02224;MGYG000004536_00884;MGYG000002007_01308;MGYG000000415_01725;MGYG000003926_01411;MGYG000000222_01291;MGYG000000174_04029;MGYG000000074_01416;MGYG000002218_02809;MGYG000001302.1_01294;MGYG000003539_00735;MGYG000000053_01501;MGYG000002203_00959;MGYG000002082_00141 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia,22U7E@171550|Rikenellaceae 0.5238095238095238 976|Bacteroidetes 0.9523809523809523 I 0.8571428571428571 malonyl CoA-acyl carrier protein transacylase 0.8571428571428571 fabD 0.8571428571428571 - 1.0 2.3.1.39 0.8571428571428571 ko:K00645 0.8571428571428571 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 0.8571428571428571 M00082 0.8571428571428571 R01626,R11671 0.8571428571428571 RC00004,RC00039,RC02727 0.8571428571428571 ko00000,ko00001,ko00002,ko01000,ko01004 0.8571428571428571 - 1.0 - 1.0 - 1.0 Acyl_transf_1 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 [acyl-carrier-protein] S-malonyltransferase. MCAT. Essential, along with EC 2.3.1.38, for the initiation of fatty-acid biosynthesis in bacteria.-!-Also provides the malonyl groups for polyketide biosynthesis.-!-The product of the reaction, malonyl-ACP, is an elongation substrate in fatty-acid biosynthesis.-!-In Mycobacterium tuberculosis, holo-ACP (the product of EC 2.7.8.7) is the preferred substrate.-!-This enzyme also forms part of the multienzyme complexes EC 4.1.1.88 and EC 4.1.1.89.-!-Malonylation of ACP is immediately followed by decarboxylation within the malonate-decarboxylase complex to yield acetyl-ACP, the catalytically active species of the decarboxylase.-!-In the enzyme from Klebsiella pneumoniae, methylmalonyl-CoA can also act as a substrate but acetyl-CoA cannot whereas the enzyme from Pseudomonas putida can use both as substrates.-!-The ACP subunit found in fatty-acid biosynthesis contains a pantetheine-4'-phosphate cofactor; that from malonate decarboxylase also contains pantetheine-4'-phosphate but in the form of a 2'-(5-triphosphoribosyl)-3'-dephospho-CoA cofactor. holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]. 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 Fatty acid biosynthesis;Prodigiosin biosynthesis;Metabolic pathways;Fatty acid metabolism 0.8571428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1681023 0 0 0 0 0 0 0 0 -A(Ala->Thr)NVDNVVENTTSAESR MGYG000000136_01850 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp000434275|m__MGYG000000136 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 800756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)QLSYTAK MGYG000002478_00307 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,4NZZK@976|Bacteroidetes,2FX99@200643|Bacteroidia,4AV66@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Outer membrane protein beta-barrel family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 5495842 6118075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6038747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)SEDTALR MGYG000002517_02764 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia 1.0 186801|Clostridia 1.0 GK 1.0 ROK family 1.0 - 1.0 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Neomycin, kanamycin and gentamicin biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 422049 0 0 151996 0 0 0 521042 0 0 0 0 0 0 0 0 0 0 0 735252 0 116060 493367 0 0 0 0 0 0 0 285338 0 0 0 0 266025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314189 0 0 0 0 0 0 0 0 0 0 0 0 357769 0 0 334801 0 0 322004 0 0 0 143394 0 0 0 0 0 0 0 0 0 0 0 889859 0 512396 326044 0 0 0 0 0 0 0 231616 0 0 0 0 450326 0 0 624680 0 0 860161 0 0 0 1547639 0 0 0 0 0 0 0 0 0 0 0 598117 0 1090858 2793961 0 0 0 0 0 0 0 1107841 0 0 0 0 899181 0 0 1559735 0 0 1730009 0 0 0 2318996 0 0 0 0 0 0 0 0 0 0 0 1050123 0 1984111 2598373 0 0 0 0 0 0 0 1871926 0 0 0 0 2071519 -A(Ala->Thr)TDLNAQELGK MGYG000002478_03813 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG2731@1|root,COG2731@2|Bacteria,4P2HG@976|Bacteroidetes,2G2E3@200643|Bacteroidia,4AVXE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Domain of unknown function (DUF386) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF386 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 5245366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3340752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)TVDDDER MGYG000000188_00824 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp003462685|m__MGYG000000188 1.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CUJQ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 pathway, signal sequence 1.0 - 1.0 - 1.0 - 1.0 ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3943507 2142077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)VELIQEGFR MGYG000000003_01804 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,2FM6J@200643|Bacteroidia,4AMTF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_2,SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 3619543 0 0 0 3171416 0 0 0 0 0 5123313 0 3135095 5497145 0 0 0 0 0 4811880 2512170 0 4330978 0 3736204 0 0 0 7182583 0 3428794 0 0 2710540 4303371 3846746 0 277211 253198 0 0 0 116706 0 0 0 0 0 203812 0 347892 353387 0 0 0 0 0 314474 196813 0 342413 0 232806 0 0 0 430433 0 433033 0 0 179441 194821 287309 0 234674 337302 0 0 0 320105 0 0 0 0 0 450263 0 245998 0 0 0 0 0 0 0 0 0 448637 0 176493 0 0 0 321833 0 0 0 0 347504 227017 129263 0 0 171118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 652965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)VGEAIVEATK MGYG000000013_01224;MGYG000002549_02739;MGYG000002281_01909;MGYG000000138_00869;MGYG000000044_00323;MGYG000004876_02584;MGYG000002455_00199;MGYG000004185_02169 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 0.75 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3130736 0 0 0 0 0 0 0 0 4323967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)VIKPSTLGLELK MGYG000001306_00997 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,2FKZT@200643|Bacteroidia,4AMS4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG NOG06228 non supervised orthologous group 1.0 susB 1.0 GO:0000272,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0004558,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:0090599,GO:1901575 1.0 3.2.1.20,3.2.1.3 1.0 ko:K01187,ko:K21574 1.0 ko00052,ko00500,ko01100,map00052,map00500,map01100 1.0 - 1.0 R00028,R00801,R00802,R01790,R01791,R06087,R06088 1.0 RC00028,RC00049,RC00077 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH31,GH97 1.0 - 1.0 GH97_C,GH97_N,Glyco_hydro_97 1.0 3.2.1.3|3.2.1.20 1.0 GH97 1.0 GH97 1.0 GH97 1.0 alpha-glucosidase. | glucan 1,4-alpha-glucosidase. maltase-glucoamylase. | lysosomal alpha-glucosidase. Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.-!-The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links. | Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides.-!-This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides.-!-EC 3.2.1.20 from mammalian intestine can catalyze similar reactions. Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. | Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1910228 0 0 0 0 2797522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116945 0 0 0 0 78119 0 0 0 0 75298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)VLELAGLK MGYG000001315_01353;MGYG000004733_00985;MGYG000000201_02098;MGYG000001423_01155;MGYG000000301_00177;MGYG000001338_02790;MGYG000002854_00092;MGYG000001689_02303;MGYG000000142_02050;MGYG000000133_00062;MGYG000000212_03064;MGYG000000213_00197;MGYG000000184_01189;MGYG000002938_00273;MGYG000000216_02346;MGYG000004852_00027;MGYG000000251_01814;MGYG000004667_05119 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)VNDIVLSK MGYG000000045_02152 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria 1.0 2|Bacteria 1.0 C 1.0 hydroxyacid-oxoacid transhydrogenase activity 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iSB619.SA_RS00885 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1606959 0 0 0 0 1011676 0 0 0 0 1581845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333598 0 0 0 0 358189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232759 0 0 0 0 519277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850842 0 0 0 0 344809 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)VVEEFNPGFTPDNK MGYG000003684_03047 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eisenbergiella|s__Eisenbergiella massiliensis|m__MGYG000003684 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,36DD9@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ECH_1,ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1968297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)YDPAAK MGYG000000074_00680 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1409@1|root,COG1409@2|Bacteria,4NF9K@976|Bacteroidetes,2FPK8@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 C terminal of Calcineurin-like phosphoesterase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Metallophos,MetallophosC,MetallophosN,PQQ_2,PQQ_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2143195 0 0 0 0 0 0 0 1836404 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Thr)YLVSK MGYG000003170_00231 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__Sutterella sp900764215|m__MGYG000003170 1.0 COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,4PQDC@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 M 1.0 OmpA family 1.0 ompA 1.0 - 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 - 1.0 DUF1134,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1488625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Trp)DAIIIR MGYG000000243_00366;MGYG000001787_00809 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 1442048 0 0 0 0 0 0 0 1030475 0 0 0 0 0 0 2350766 0 0 0 0 3253673 0 0 0 0 4976848 0 0 0 0 1156184 0 0 0 0 1028630 0 0 1422310 0 0 0 0 0 0 0 1209956 0 0 0 0 0 0 6334840 0 0 0 0 2423800 0 0 0 0 2573609 0 0 0 0 1894718 0 0 0 0 372805 0 0 777190 0 0 0 0 0 0 0 707235 0 0 0 0 0 0 378737 0 0 0 0 475260 0 0 0 0 578111 0 0 0 0 532642 0 0 0 0 114530 0 0 53418 0 0 0 0 0 0 0 878153 0 0 0 0 0 0 2114477 0 0 0 0 1011619 0 0 0 0 1560684 0 0 0 0 1389748 0 0 0 0 67672 0 0 383934 0 0 0 0 0 0 0 146259 0 0 0 0 0 0 63086 0 0 0 0 792316 0 0 0 0 2319972 0 0 0 0 214722 0 0 0 0 331452 -A(Ala->Trp)NAIIIR MGYG000002455_04590;MGYG000000029_02971;MGYG000004876_03505;MGYG000003681_00721;MGYG000001306_01782;MGYG000000098_01490;MGYG000003367_00322;MGYG000000196_03462;MGYG000001337_02575;MGYG000001346_03050 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 0.6 976|Bacteroidetes 1.0 C 0.6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 0.6 serA 0.6 - 1.0 1.1.1.399,1.1.1.95 0.6 ko:K00058 0.6 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 0.6 M00020 0.6 R01513 0.6 RC00031 0.6 ko00000,ko00001,ko00002,ko01000,ko04147 0.6 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 0.6 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 0.6 0.6 0.6 0.6 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 0.6 none 1.0 0 0 0 83638889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72176315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325140889 0 0 0 64633128 436479536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31632697 0 0 0 51107003 35309327 0 34958338 0 0 0 0 0 0 0 0 0 0 0 0 33416513 77537611 40563642 0 0 33180140 0 0 40444571 0 0 0 0 0 0 0 40285592 0 36046225 48177594 45335947 0 42501611 0 48921675 43298712 0 0 39780800 0 42938437 0 35125482 40649428 100375912 0 43085585 0 0 181288197 32797543 0 55263490 0 50856460 0 40470734 0 0 0 0 0 0 45195078 0 0 0 0 0 0 0 0 0 0 0 0 0 23269634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Trp)NAIILR MGYG000001302.1_00942;MGYG000004876_03505;MGYG000004763_00834;MGYG000003681_00721;MGYG000001835_00780;MGYG000000196_03462;MGYG000001337_02575;MGYG000001346_03050 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 C 0.5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 0.75 serA 0.625 - 1.0 1.1.1.399,1.1.1.95 0.75 ko:K00058 0.75 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 0.75 M00020 0.75 R01513 0.75 RC00031 0.75 ko00000,ko00001,ko00002,ko01000,ko04147 0.75 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 0.75 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 0.75 0.75 0.75 0.75 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6586980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59691534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 43714184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31883747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Trp)NALIIR MGYG000002455_04590;MGYG000001302.1_00942;MGYG000000029_02971;MGYG000003312_01933;MGYG000004876_03505;MGYG000004763_00834;MGYG000000013_04188;MGYG000001306_01782;MGYG000002561_02267;MGYG000000196_03462;MGYG000002549_01443;MGYG000001337_02575;MGYG000004899_01858;MGYG000001345_02371;MGYG000000224_02581;MGYG000003681_00721;MGYG000000098_01490;MGYG000001789_00954;MGYG000001346_03050 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 0.47368421052631576 976|Bacteroidetes 1.0 C 0.47368421052631576 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 0.5789473684210527 serA 0.5263157894736842 - 1.0 1.1.1.399,1.1.1.95 0.5789473684210527 ko:K00058 0.5789473684210527 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 0.5789473684210527 M00020 0.5789473684210527 R01513 0.5789473684210527 RC00031 0.5789473684210527 ko00000,ko00001,ko00002,ko01000,ko04147 0.5789473684210527 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 0.5789473684210527 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 0.5789473684210527 0.5789473684210527 0.5789473684210527 0.5789473684210527 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 0.5789473684210527 none 1.0 0 65431464 70540623 0 53580727 0 0 0 75540820 90240795 0 0 0 0 0 0 75484408 0 0 0 0 54374974 186704583 0 0 77820892 76373441 224554865 0 84137313 0 82568109 62351865 59896871 0 0 0 0 38712673 0 0 47839133 0 0 0 55372214 0 0 65697993 55658064 0 0 53996097 0 0 0 0 0 47157591 0 0 0 0 0 0 383517300 0 0 49836555 0 0 0 48569031 0 48453152 52198027 0 0 0 0 39803486 0 0 0 0 0 0 0 0 33031058 0 27214992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35870667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360783 0 0 0 144372829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Trp)NALLIR MGYG000004763_00834;MGYG000001789_00954 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,22WZN@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 CH 0.5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32015262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Tyr)ATLMLK MGYG000002549_01341 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG3637@1|root,COG3637@2|Bacteria,4PM3D@976|Bacteroidetes,2G0AF@200643|Bacteroidia,4AV3U@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 1005203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1624947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 667531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Tyr)IAPDETPLYR MGYG000002438_01883 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 435591.BDI_2653|- 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3295228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Tyr)VAEGANMPTTR MGYG000000095_00309 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__GCA-900066755|s__GCA-900066755 sp902363085|m__MGYG000000095 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,21ZF0@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 - 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 1028704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Tyr)YSSGKPALGVGAGNTPVIIDDTADVR MGYG000000133_00993 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2398942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1721565 0 0 0 0 2055320 -A(Ala->Val)AGQIDC(Carbamidomethyl)SR MGYG000002506_04505;MGYG000002323_00920 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG3477@1|root,COG3477@2|Bacteria,1MV9E@1224|Proteobacteria,1RYHM@1236|Gammaproteobacteria,3XQGU@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 response to acidic pH 1.0 yagU 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016020,GO:0044464,GO:0050896,GO:0071944 1.0 - 1.0 ko:K08996 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF1440 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4207997 0 0 0 9567726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8005675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)AITPVVNATVER MGYG000002794_00763;MGYG000002143_01959;MGYG000001733_00672;MGYG000004196_01673;MGYG000004475_00752 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)ALQYSTTEGFPR MGYG000001733_01320 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550615|m__MGYG000001733 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,25WJ6@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 EK 1.0 Aminotransferase class I and II 1.0 - 1.0 - 1.0 - 1.0 ko:K05825 1.0 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 1.0 - 1.0 R01939 1.0 RC00006 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2,GntR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Lysine biosynthesis;Metabolic pathways;2-Oxocarboxylic acid metabolism 1.0 none 1.0 745341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)AQGILTVR MGYG000000463_01481;MGYG000002114_00088;MGYG000002229_00282;MGYG000002006_01658;MGYG000004482_00393;MGYG000004594_00959;MGYG000004667_00970;MGYG000002727_00240;MGYG000001319_00729;MGYG000004680_00577;MGYG000000145_01088;MGYG000004760_00878;MGYG000002670_01671;MGYG000001688_03814;MGYG000001698_00702;MGYG000002926_01683;MGYG000001757_01805;MGYG000002143_00035;MGYG000002057_00345;MGYG000000728_00587;MGYG000002103_01314;MGYG000000084_02423;MGYG000000205_02701;MGYG000000152_05136;MGYG000004663_01541;MGYG000004866_01724;MGYG000002059_01602;MGYG000004380_01725;MGYG000002025_01833;MGYG000004475_00310;MGYG000003422_01232;MGYG000000242_00224;MGYG000002139_00077;MGYG000002794_01254;MGYG000004718_01489;MGYG000004517_00262;MGYG000001733_00637;MGYG000000175_01356;MGYG000002552_02286;MGYG000000404_01435;MGYG000000387_01345;MGYG000004784_01123;MGYG000002492_01692;MGYG000004845_02015;MGYG000001439_01567;MGYG000000371_01679;MGYG000000489_00801;MGYG000000281_03419;MGYG000000142_02834;MGYG000002702_00763;MGYG000002099_01951;MGYG000004487_00114;MGYG000000233_02503;MGYG000000031_02405;MGYG000001619_00896;MGYG000000179_00100;MGYG000000690_00823;MGYG000003074_00103;MGYG000000255_02207;MGYG000001564_02842;MGYG000000198_00250;MGYG000002945_01502;MGYG000001496_03326;MGYG000003921_01571;MGYG000001748_00979;MGYG000001675_00187;MGYG000003628_00298;MGYG000001646_00500;MGYG000003656_02122;MGYG000002925_01270;MGYG000002126_00460;MGYG000003694_01656;MGYG000001637_01169;MGYG000000087_02439 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.17567567567567569 186801|Clostridia 1.0 G 0.9459459459459459 Belongs to the PEP-utilizing enzyme family 0.6756756756756757 ppdK 0.9459459459459459 - 1.0 2.7.9.1 0.9459459459459459 ko:K01006 0.9459459459459459 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.9459459459459459 M00169,M00171,M00172,M00173 0.9459459459459459 R00206 0.9459459459459459 RC00002,RC00015 0.9459459459459459 ko00000,ko00001,ko00002,ko01000 0.9459459459459459 - 0.9459459459459459 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9459459459459459 - 1.0 - 1.0 - 1.0 GT1 0.9459459459459459 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.9459459459459459 0.9459459459459459 0.9459459459459459 0.9459459459459459 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 0.9459459459459459 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)ASNESFGYNTDEIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1052204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2020899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12679346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3503042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)ATILAK MGYG000000271_01703;MGYG000004271_02802 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the cysteine synthase cystathionine beta- synthase family 1.0 cysK 1.0 - 1.0 2.5.1.47 1.0 ko:K01738 1.0 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00021 1.0 R00897,R03601,R04859 1.0 RC00020,RC02814,RC02821 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PALP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 cysteine synthase. OAS sulfhydrylase. Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors.-!-Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53.-!-Formerly EC 4.2.99.8. hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine. 1.0 1.0 1.0 1.0 Sulfur metabolism;Carbon metabolism;Metabolic pathways;Cysteine and methionine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)AVEAAPK MGYG000003770_00148;MGYG000002707_01485;MGYG000000099_00102;MGYG000002944_00191 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,269AI@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 998814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1169392 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)AVEADLKDLK MGYG000002528_00169 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2183757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)DKEMTAAGK MGYG000000084_02247;MGYG000001157_02455 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94029 0 0 0 0 0 0 0 0 0 0 0 61823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4371399 0 1345855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193644 0 0 0 0 541842 0 0 0 0 587015 0 497520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 813024 0 0 0 0 44673 0 0 0 0 485466 0 189529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)GEVYNVGGHNEK MGYG000001599_00610 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900544075|m__MGYG000001599 1.0 COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,2FMUH@200643|Bacteroidia,4AME0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily 1.0 rfbB 1.0 - 1.0 4.2.1.46 1.0 ko:K01710 1.0 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 1.0 M00793 1.0 R06513 1.0 RC00402 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 dTDP-glucose 4,6-dehydratase. - - dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. 1.0 1.0 1.0 1.0 Acarbose and validamycin biosynthesis;Biosynthesis of vancomycin group antibiotics;Polyketide sugar unit biosynthesis;Streptomycin biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)HLATIEGK MGYG000002517_00959;MGYG000000562_02319;MGYG000000389_00578;MGYG000000154_00174 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 0.75 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 662327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1875934 0 0 0 0 2047157 0 0 0 0 1543137 0 0 0 0 0 0 0 0 0 0 0 416382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 871996 0 0 0 0 1761301 0 0 0 0 1436739 0 0 0 0 0 0 0 0 0 0 0 2528571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6357689 0 0 0 0 4242338 0 0 0 0 4287862 0 0 0 0 0 0 0 0 0 0 0 560369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2014991 0 0 0 0 326474 0 0 0 0 1374954 0 0 0 0 0 0 0 0 0 0 0 247151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1634145 0 0 0 0 1356881 0 0 0 0 1183286 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)HLATLEGK MGYG000002963_01235 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerosporobacter|s__Anaerosporobacter mobilis|m__MGYG000002963 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,36EA6@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2281945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)IAEAIAEATK MGYG000001835_00603 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp000432735|m__MGYG000001835 1.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NIEK@976|Bacteroidetes,2FMAP@200643|Bacteroidia,4AKI4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 Psort location CytoplasmicMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2738644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)LQEAVYNYIK MGYG000001345_01307;MGYG000001378_03234;MGYG000000013_03191 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,27W9G@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 NADH:flavin oxidoreductase / NADH oxidase family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Oxidored_FMN,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 960538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)LVLVNLAPR MGYG000000074_02196 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,2FNV6@200643|Bacteroidia,22U5Q@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation 1.0 metG 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.10 1.0 ko:K01874 1.0 ko00450,ko00970,map00450,map00970 1.0 M00359,M00360 1.0 R03659,R04773 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,tRNA-synt_1g,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 GH55 1.0 methionine--tRNA ligase. MetRS. In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9. ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis;Selenocompound metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 778694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)LVVTGAGEK MGYG000000233_02445 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,21Z2Z@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 I 1.0 Enoyl-CoA hydratase/isomerase 1.0 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1725428 0 0 0 0 0 0 1328187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Val)SAAVDAQAEAIKNQASSTVDAQAEAIR MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146494 0 0 0 0 0 0 0 0 -A(Ala->Val)TIIGHIQR MGYG000000255_02050;MGYG000000233_02644;MGYG000000087_01570;MGYG000000205_01904 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,21XPK@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1995379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1314235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228756 0 0 0 0 0 0 0 0 0 0 1248724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1162959 0 0 0 0 0 0 1165025 0 0 0 0 -A(Ala->Val)YEPDTAQSELGVVLR MGYG000000074_02075 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF4@976|Bacteroidetes,2G3EZ@200643|Bacteroidia,22VH9@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 273279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550080 0 0 0 0 0 0 0 0 0 0 0 0 0 295335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 801581 0 0 0 0 0 0 0 0 0 0 0 0 0 1579812 0 468245 0 830502 0 0 0 0 0 1808491 0 0 0 0 0 0 0 0 -A(Ala->Xle)GIVGLPNVGK MGYG000001346_01808;MGYG000000224_00729;MGYG000003470_01179 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,2FMWX@200643|Bacteroidia,4AMIJ@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 J 1.0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner 1.0 ychF 1.0 - 1.0 - 1.0 ko:K06942 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 MMR_HSR1,YchF-GTPase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3016179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3318986 0 0 0 0 0 0 0 0 0 0 -A(Ala->Xle)IDPAAMAK MGYG000001310_00280;MGYG000002772_01916;MGYG000000249_01751 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 0.6666666666666666 adh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13718540 0 0 0 0 0 0 0 0 0 0 0 7610580 0 0 0 6718743 0 0 11789113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7306401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Xle)SYGETGLDESAGR MGYG000002721_02202 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-873|s__CAG-873 sp009775195|m__MGYG000002721 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1530372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Ala->Xle)VDLLVEGK MGYG000000159_01307 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Sellimonas|s__Sellimonas intestinalis|m__MGYG000000159 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,2682U@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Carbonyl)ALNPHIVVK MGYG000000243_01624;MGYG000002478_03826 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,2FNM3@200643|Bacteroidia,4AM98@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616,ko:K08314 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CBS,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 915606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3999893 0 0 0 0 3275601 0 0 1392551 0 4398963 0 0 0 0 0 0 0 0 1030087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2000703 0 0 0 0 1914765 0 0 970678 0 1637691 0 0 0 0 0 0 0 0 919619 0 88856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 799347 0 0 0 0 476655 0 0 86609 0 0 0 0 0 0 0 0 0 0 216602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -A(Carbonyl)TGAMAALLK MGYG000002517_01537 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia 1.0 186801|Clostridia 1.0 H 1.0 Belongs to the formate--tetrahydrofolate ligase family 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1121469 0 0 0 0 0 0 0 0 -AA(Ala->Asp)AAAAEAEAK MGYG000002293_01607 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1562231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 782546 0 2545259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Asp)YLFNHVEYR MGYG000004893_00001 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A sp900555485|m__MGYG000004893 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,378RN@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 909059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Glu)AGTAAVSAAEQTK MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 712537 0 0 0 2585726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564808 0 939275 0 0 0 0 0 2101365 0 0 0 0 0 0 0 0 -AA(Ala->Gly)ADLLVLAYHR MGYG000003695_00289;MGYG000004558_01494;MGYG000000249_00466;MGYG000003581_01363;MGYG000002279_00355;MGYG000002992_01118;MGYG000001338_01660;MGYG000000038_02127;MGYG000000184_00391 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily 1.0 rfbB 1.0 - 1.0 4.2.1.46 1.0 ko:K01710 1.0 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 1.0 M00793 1.0 R06513 1.0 RC00402 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 dTDP-glucose 4,6-dehydratase. - - dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. 1.0 1.0 1.0 1.0 Acarbose and validamycin biosynthesis;Biosynthesis of vancomycin group antibiotics;Polyketide sugar unit biosynthesis;Streptomycin biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 734508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374927 0 0 0 0 0 0 422276 0 0 0 0 0 127121 0 0 0 0 0 0 0 0 0 0 435939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Gly)DDAAGLAISEK MGYG000001777_01359;MGYG000003422_01458;MGYG000000362_01735;MGYG000003422_01457;MGYG000000217_00038;MGYG000002934_00200;MGYG000001814_01561;MGYG000001514_01163 domain d__Bacteria 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae 0.375 186801|Clostridia 0.75 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 0.625 - 0.75 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2066248 0 0 0 0 2041449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Gly)DDAAGLSISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 1741351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1423102 0 0 0 0 0 1327070 0 0 1277453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 811255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Gly)DDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6465599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Gly)MLAIMNPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1186600 1929629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Gly)MLTIMNPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1270812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Pro)AQNIVPNTTGAAK MGYG000003504_01686 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-314|g__CAG-1435|s__CAG-1435 sp003537755|m__MGYG000003504 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 922961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Pro)DDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 450601 0 0 0 0 0 238147 0 0 0 0 0 0 0 0 0 0 0 813230 1449754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 901162 0 0 0 0 0 1533606 0 0 0 0 1420442 0 0 0 0 0 0 1827625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1658723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Ser)ASESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Ser)DDAAGLSISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1234319 0 0 0 0 0 3811613 1413880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 206224 0 0 0 0 472723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290497 0 0 0 0 0 0 350711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 576997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Ser)DDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 255137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154083 0 215493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374076 0 514002 235175 386252 403483 558404 339260 0 849515 564977 443007 481058 274683 0 419424 475396 0 442030 0 0 424972 0 435456 401036 0 363578 187508 488052 0 247655 293391 673703 268590 377886 347088 274650 718055 256875 0 332214 0 342305 407996 367192 0 349419 0 0 0 0 207649 0 0 388615 168261 0 0 528267 490914 558691 299417 304613 0 209663 0 227506 0 475534 0 0 0 0 0 244201 186349 367087 0 0 152287 0 0 0 455375 0 0 0 0 0 343780 0 0 0 0 507154 440935 0 175810 0 0 370393 502124 0 0 264012 0 0 0 0 334224 333374 330530 0 0 19627721 7401456 11577962 7134919 7924266 21446020 18003105 10021905 28255393 21564367 8004535 54534562 21692731 15544662 22120373 8808892 24834696 3990712 25509650 32257591 14649337 13075779 3144264 16042796 17975935 22555573 16242184 3381047 3922889 34171633 5229084 4806555 9073431 25909040 10244195 16101614 26743766 13960548 -AA(Ala->Ser)GAAGVIRPSK MGYG000001300_00059;MGYG000003899_00538;MGYG000002641_02329;MGYG000002610_01595;MGYG000004719_01899;MGYG000003166_01772;MGYG000003921_01901;MGYG000001157_01521;MGYG000003937_01168;MGYG000000573_01714;MGYG000000589_01770;MGYG000000084_01199;MGYG000004732_01998 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 0.9230769230769231 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 0.9230769230769231 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Phosphotransferase system (PTS) 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2539535 0 -AA(Ala->Ser)LPSTTFDGTYLR MGYG000003697_02264 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG4772@1|root,COG4772@2|Bacteria,4NF0U@976|Bacteroidetes,2FM7N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1329778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1004011 0 0 0 0 1336922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Ser)PILLEPIMR MGYG000000171_02843;MGYG000004733_01212 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Ser)VDAGAASAR MGYG000002854_00976 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Peptostreptococcaceae|g__Peptacetobacter|s__Peptacetobacter sp900539645|m__MGYG000002854 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,22HEI@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12172014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8744214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Ser)VETGADAAGR MGYG000000249_01483;MGYG000004799_00497;MGYG000001379_02073;MGYG000000268_01898;MGYG000002596_02056 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1452056 0 0 0 0 0 0 0 0 0 0 0 0 3098360 0 0 0 0 2385639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Thr)AQTDNVHRPFYPMLIFR MGYG000002469_00856 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium breve|m__MGYG000002469 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 501548 1174442 0 0 0 0 0 0 0 0 0 842328 970570 0 0 0 0 0 0 0 0 0 955169 973452 0 0 0 978235 0 834415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Thr)ASESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2311699 0 0 0 0 0 0 0 3496962 0 0 0 0 3946242 0 0 0 0 0 0 0 3440651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13542061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6493339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 767866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5720695 0 0 0 0 0 0 0 5148507 0 0 0 0 0 0 0 0 0 0 0 0 5988994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Thr)ASESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 961374 0 0 0 0 0 0 0 0 0 0 0 0 933804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1091767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1014733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Thr)EAYFLLAEAK MGYG000002478_01404;MGYG000004797_04332 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1708918 1850725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2112786 0 1483055 0 0 0 0 0 0 0 2045308 0 1641716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Thr)EIPEAIR MGYG000000136_02061;MGYG000002670_00403;MGYG000001315_01353;MGYG000002234_01458;MGYG000004733_00985;MGYG000003891_01006;MGYG000000252_01802;MGYG000000280_01284;MGYG000000031_02249;MGYG000000142_02050;MGYG000004630_00952;MGYG000002492_00392;MGYG000000135_01188;MGYG000000690_01576;MGYG000000028_01605;MGYG000004689_01598;MGYG000002517_02856;MGYG000000002_00865;MGYG000002966_02558;MGYG000001186_01095;MGYG000000213_00197;MGYG000004296_00406;MGYG000000806_01299;MGYG000002278_02309;MGYG000000050_01189;MGYG000002298_00345;MGYG000000193_02113;MGYG000000201_02098;MGYG000000301_00177;MGYG000004879_01580;MGYG000001338_02790;MGYG000002528_01856;MGYG000000164_02747;MGYG000001689_02303;MGYG000000562_01931;MGYG000000133_00062;MGYG000000212_03064;MGYG000000184_01189;MGYG000003694_02445;MGYG000000216_02346;MGYG000000251_01814;MGYG000001637_00014;MGYG000000187_01741 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.46511627906976744 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3864447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Thr)LGAGVDKLANTVR MGYG000000245_00416;MGYG000002492_02075;MGYG000004271_02056;MGYG000000489_01318;MGYG000000271_00294 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Thr)VLVPNDVSNEAR MGYG000000179_03320;MGYG000001311_00514 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,268FE@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 P 1.0 NLPA lipoprotein 1.0 metQ 1.0 - 1.0 - 1.0 ko:K02073 1.0 ko02010,map02010 1.0 M00238 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.24 1.0 - 1.0 - 1.0 Lipoprotein_9,SBP_bac_3,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2402120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Val)ALGFFEAAGYTVENGK MGYG000002926_01410 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 314430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296495 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907748 0 0 0 0 1177227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Val)ASESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 909114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 653043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Val)EAPATEEPKAESAE MGYG000000236_01758 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,2FNPH@200643|Bacteroidia,4AK8D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal protein L17 1.0 rplQ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02879 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Ribosomal_L17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1326408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Val)EDLLDAEAYK MGYG000000196_02494 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,2FT3J@200643|Bacteroidia,4AQKP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein 1.0 gcvH 1.0 - 1.0 - 1.0 ko:K02437 1.0 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 1.0 M00532 1.0 R01221 1.0 RC00022,RC02834 1.0 ko00000,ko00001,ko00002 1.0 - 1.0 - 1.0 - 1.0 GCV_H 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 1181914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154204 0 -AA(Ala->Val)ITPVVNATVER MGYG000002794_00763;MGYG000002143_01959;MGYG000001733_00672;MGYG000004196_01673;MGYG000004475_00752 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 1190375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 914957 0 0 0 0 0 0 0 0 0 0 1090272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AA(Ala->Val)TQALGMIETK MGYG000000413_00044 genome d__Bacteria|p__Firmicutes_B|c__Peptococcia|o__Peptococcales|f__Peptococcaceae|g__UBA7185|s__|m__MGYG000000413 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3WM1H@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAA(Ala->Asn)SESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1623239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAA(Ala->Asp)SESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 862830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAA(Ala->Met)GTAAVSAAEQTK MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3917630 0 0 0 0 -AAA(Ala->Met)QNIVPNTTGAAK MGYG000003504_01686 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-314|g__CAG-1435|s__CAG-1435 sp003537755|m__MGYG000003504 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAA(Ala->Ser)SESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAA(Ala->Thr)SESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2792354 7638729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6807142 0 0 0 0 4898068 7027324 0 0 0 0 0 0 0 0 0 0 6362155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1606096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4439376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1321407 0 0 0 0 0 563369 0 0 0 0 0 0 0 0 0 0 672941 0 0 0 0 0 0 0 0 -AAA(Ala->Thr)SESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 939875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 679894 0 997245 0 0 0 0 805230 0 0 0 0 0 0 509769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAA(Ala->Thr)SESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1255091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAAAAAEAAAETEATEEAPAEA MGYG000003697_02087;MGYG000002834_00364 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 352779 0 380553 0 0 0 0 0 0 531369 0 0 0 338253 0 146190 0 0 0 0 365782 0 0 0 0 0 0 0 0 0 481551 0 0 0 0 0 0 0 0 0 522675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1296181 0 716319 0 0 0 0 0 0 872996 0 0 0 647398 0 2380515 0 0 0 0 5463481 0 0 0 0 2163485 0 0 0 0 841796 0 0 0 0 926969 0 0 1273223 0 299613 0 0 0 0 0 0 0 0 0 0 433692 0 405385 0 0 0 0 0 0 0 0 0 239950 0 0 0 0 2127202 0 0 0 0 0 -AAAAAAAAK MGYG000003279_02451 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900541585|m__MGYG000003279 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2491599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAADTSAADKPADEGKAE MGYG000001292_00236 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG3937@1|root,COG3937@2|Bacteria,2GS3M@201174|Actinobacteria,4D1FE@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 S 1.0 granule-associated protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Phasin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1476068 0 0 0 0 143773 0 0 0 0 1136758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAALDSLPEAWK MGYG000001313_01371 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,2FR40@200643|Bacteroidia,4AMEY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Belongs to the short-chain dehydrogenases reductases (SDR) family 1.0 ydfG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,adh_short 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355616 0 0 0 0 0 0 0 0 0 266036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479453 0 0 0 0 456814 0 0 0 0 282597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397245 0 0 0 0 622761 0 0 0 0 462006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAALQTPLYSYLGGIHVGK MGYG000001607_00631 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_B|s__Dorea_B phocaeensis|m__MGYG000001607 1.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,21XMD@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAAQVER MGYG000004797_04190 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0845@1|root,COG0845@2|Bacteria,4NECC@976|Bacteroidetes,2FMDD@200643|Bacteroidia,4ANZR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Auxiliary transport protein, membrane fusion protein (MFP) family protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01993 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 767428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1116139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 627717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1456868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAADFGDGSQIDR MGYG000001302.1_02383 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG5492@1|root,COG5492@2|Bacteria,4NIA5@976|Bacteroidetes,2FN73@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 N 1.0 domain, Protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glug,Mfa_like_1,Peptidase_M26_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 608258 864236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 845023 0 0 0 0 0 0 0 0 0 0 0 0 0 592431 0 0 0 0 443767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 703828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209110 -AAAADVGNDHR MGYG000002492_00629;MGYG000001637_01195;MGYG000003694_02366 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 1.0 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 GABAergic synapse;Necroptosis;Glyoxylate and dicarboxylate metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 31905 115432 147032 112946 176751 0 124184 131828 109082 244307 248716 0 196010 0 253480 84685 141933 299732 0 79626 126155 149088 232762 0 145262 0 55744 290716 141707 0 108770 31818 84529 72473 0 0 0 147052 361168 343845 382194 565653 763658 211220 599668 486195 341100 263405 532589 269053 671571 337692 308081 457687 196895 3857790 0 373413 426295 192679 2236062 373814 260464 375973 494374 4286980 312293 120725 563573 345271 418970 381521 301833 456384 272191 512720 438838 901728 1940165 748760 649644 689890 477994 749285 704563 624081 1014732 806012 950597 820044 947742 1480506 670851 99791 0 812916 837607 911962 760986 643988 662513 795756 698545 1483753 913282 606449 1034684 762431 2596579 1043125 733487 620305 852680 2548482 68913 0 95216 0 60120 48487 147083 0 126590 107912 162263 0 0 83625 0 196084 78805 856546 0 31236 0 169522 93977 106693 0 44419 40052 984710 101735 115413 294950 0 122808 0 0 0 0 268012 0 0 0 0 0 0 76937 0 0 0 0 0 0 111156 172870 0 0 0 0 0 114785 72618 0 82348 0 0 90702 0 0 0 44009 49276 111128 0 115750 241258 0 0 -AAAAEAAAETEATEEAPAEA MGYG000003697_02087;MGYG000002834_00364 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053725 0 625522 852680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1190977 0 1057550 0 0 0 0 0 0 0 0 642336 0 0 0 0 895087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAEGNEDAKNAIEVLC(Carbamidomethyl)YGIAK MGYG000000201_02960 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066145|m__MGYG000000201 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAEQEVIADDAAESAAE MGYG000003937_01585 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,3WKHQ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 608137 0 0 0 0 0 0 0 0 0 0 0 0 0 285916 0 0 680468 0 900950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAETLADVK MGYG000001345_01346;MGYG000002549_00032;MGYG000000196_04075 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,2FMAT@200643|Bacteroidia,4AP4X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the class-I aminoacyl-tRNA synthetase family 1.0 trpS 1.0 - 1.0 6.1.1.2 1.0 ko:K01867 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03664 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 tRNA-synt_1b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 tryptophan--tRNA ligase. tryptophanyl-tRNA synthetase. - ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 963907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 661554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 817419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAEYLDTYADGSK MGYG000002528_01780 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1345948 0 0 0 0 809370 170916 0 0 0 1256313 1601304 0 0 135972 0 0 404169 0 0 448433 590203 4041027 573575 0 784155 2191981 0 0 0 0 0 0 0 0 0 0 0 7038234 0 0 0 1495883 4280240 5133887 0 0 0 6609221 415822 0 2591751 1609280 525879 0 360916 0 0 836236 212199 3474569 2285444 0 948172 5126887 0 0 0 0 1073725 0 0 0 0 0 0 1239435 0 0 0 15219841 2268161 3293219 0 581096 0 2888090 7292317 0 0 4303731 2627506 0 293628 0 374689 2694952 0 240297 0 0 0 0 0 0 0 0 153989 0 0 0 0 0 0 332074 0 0 0 0 506264 0 0 121746 0 335779 7138559 0 104684 3982998 0 0 0 0 67100 0 0 0 0 0 218992 0 0 0 0 0 0 0 0 0 0 0 0 594132 0 0 0 532079 915178 0 0 0 0 923704 0 0 0 0 0 0 0 0 0 0 -AAAAEYLDTYADGSKNGAATDKLVAALEAC(Carbamidomethyl)GC(Carbamidomethyl)DAAK MGYG000002528_01780 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4779533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAEYLDTYTDGK MGYG000000080_02732 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1721321 0 0 0 0 0 0 0 0 0 -AAAAEYLDTYTDGKK MGYG000000080_02732 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7507500 0 0 0 0 0 0 0 0 0 -AAAAGAAAPAAEAK MGYG000001494_00393;MGYG000002447_00580 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Mesosutterella 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4H4X8@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 344623 0 0 361929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 703273 479344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAGC(Carbamidomethyl)AESAEILK MGYG000002274_02671;MGYG000002545_01451 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 1226603 1292439 1118791 1444399 0 1585516 1272107 0 0 0 1687198 1437772 1056597 0 1009487 0 1037022 3503426 0 0 0 1333590 4049980 2014819 1076215 0 1241802 4467057 0 1683672 1489119 1479711 1079306 0 1148619 1393794 1114655 1182576 289154 384352 0 381691 0 551062 730122 0 0 0 0 0 618985 0 339966 0 0 715338 0 0 0 269558 912407 635623 412964 0 568788 897104 0 525468 493171 357920 0 0 0 517818 137754 839778 1561643 462804 560524 1176866 0 2110824 1961968 0 0 0 1579247 1436988 1610029 0 1346843 0 1858789 6705260 0 0 0 1105537 6644270 2939503 1570014 1731152 1370593 6357977 0 1791357 1919893 1904277 1051588 0 1935541 1850438 1443856 1443757 1191957 615652 1246058 1303150 0 924511 543361 0 0 0 922817 729102 1550154 0 1042599 0 1036110 4166611 0 0 0 1024350 5479827 913571 656306 1136039 1100291 6006846 0 923771 2550567 1075556 1283969 0 978681 991885 1164587 1081277 0 449880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2647611 0 0 0 474957 2841185 0 1361148 0 0 2452059 0 1094314 0 0 0 0 0 780998 0 337275 -AAAAGC(Carbamidomethyl)PDAADVLEK MGYG000000077_01058 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum soehngenii|m__MGYG000000077 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAGC(Carbamidomethyl)PDAAEVLEK MGYG000000262_01692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 631091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAGC(Carbamidomethyl)PDAAEVLEKK MGYG000000262_01692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 276534 0 0 0 0 0 0 0 0 0 602661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176751 0 0 0 0 0 0 292095 0 0 554441 0 0 0 0 0 0 0 0 0 318956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 205755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1445928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 861260 0 0 0 0 0 0 558374 0 0 619827 0 0 0 0 0 0 0 0 0 469132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 716905 0 1427451 0 0 0 0 589819 -AAAAGC(Carbamidomethyl)PDAK MGYG000000271_02509;MGYG000002517_00959;MGYG000000356_00314;MGYG000000280_02128;MGYG000000389_00578;MGYG000000076_02414;MGYG000000154_00174 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 1697292 623189 236071 1662113 601167 652274 1564206 657311 1652317 1039266 1764342 981509 860402 1040406 1899235 759213 1237126 2398605 1903933 0 1841225 669345 2277680 788686 1544590 1207026 1951126 2776434 624190 1615966 392937 319705 287664 1996672 708593 1795593 1374186 427357 113679 0 0 0 86722 66141 125480 0 0 0 130442 0 75386 185592 0 0 102129 279397 75671 88154 0 0 641338 64164 130110 0 0 732589 0 47494 0 0 0 111239 0 0 106227 0 445365 97068 0 251784 107867 86886 190359 401116 334459 301797 186205 271159 326863 315499 546126 339618 447290 0 398730 640764 1028858 164179 98564 349755 709850 620122 676445 224335 201240 311795 41964 118593 0 555935 470182 493092 654792 0 3027964 672124 161473 6370509 571410 660899 4644815 2959125 6639542 1092174 661487 818978 555638 2955332 1868120 991410 1832969 407590 1939203 3845323 1586086 190740 0 99301 4466428 3198059 3598909 350862 576893 1514626 253215 628393 176425 1665779 2815971 1652626 4174323 304246 3238727 2183608 1561265 0 1061790 968634 2929412 1137941 2918375 2897515 1839350 1985949 321408 3638388 4461766 752063 2817102 1104421 686708 1879638 2634089 887804 1622895 1244802 2269075 2785247 3473102 912390 557488 1026165 1281222 168488 2642947 1755508 3027923 3646063 3519466 1351611 -AAAAGC(Carbamidomethyl)TESAEILK MGYG000000022_01634;MGYG000002040_01920 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 260159 509047 552005 0 436038 379527 376507 392837 415236 366122 636916 302791 438460 438276 336591 447206 278711 1632728 291761 0 429113 478224 1739694 348471 354809 350016 324976 1221448 396557 398737 450800 515356 504047 348156 410313 307210 0 280174 781075 678076 814292 716129 736937 673445 819442 791747 899720 1204330 1341677 633984 828370 706258 707305 800526 892584 10816558 403758 797162 612394 603660 12774228 803679 591279 824455 1090767 12244484 632339 477269 712206 683333 769234 771997 789070 883885 988328 791905 1416906 2067722 1458237 1584140 1444593 1842635 1694080 1517083 1416667 2093908 1793227 996843 1530403 1939508 1715468 1575908 2112342 6479260 1858815 1104991 1305672 1743379 7739014 1688848 1866828 1639872 1447288 8031148 1856740 1683219 1704439 1772714 1565038 1660925 1989454 1765471 2073032 2119958 410971 621752 597128 669631 612335 488850 590204 343164 736433 802693 331871 491099 657455 346568 475828 433161 753908 2283600 455329 549495 552038 520844 1679666 345215 601698 408691 497264 2306661 633887 594635 619300 648405 578474 0 671615 462400 439695 612289 929582 796202 1732114 1197351 980616 1244167 1456961 1565944 849149 1508101 976860 955485 1149532 1074795 1112278 1121493 1053716 11068902 1255689 861707 924151 981404 12164596 1256359 1202238 993227 1191670 13261180 1234576 774202 1109189 1096556 1728501 1063096 1212158 1010733 1106161 1859932 -AAAAGCT(Thr->Gln)ESAEILK MGYG000000022_01634;MGYG000002040_01920 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1044120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAGENEEWSLDYPK MGYG000001364_02910;MGYG000000273_02921;MGYG000001306_00797;MGYG000003693_00002 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1592@1|root,COG1592@2|Bacteria,4NH0J@976|Bacteroidetes,2FNC9@200643|Bacteroidia,4AKRD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 1.0 rbr 1.0 GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 952457 0 826034 1162029 0 825556 1055910 1299039 1109876 1245217 1173337 1134696 0 1169337 1337558 0 1321930 5068349 0 0 634403 0 6101312 698848 1046107 1115123 1219750 5427749 768347 0 822869 0 797975 0 0 871172 1193266 832741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 673809 0 0 0 0 787195 0 0 0 0 565435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAGENEEWSLDYPR(Arg->Lys) MGYG000000042_01353 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900066445|m__MGYG000000042 1.0 COG1592@1|root,COG1592@2|Bacteria,4NH0J@976|Bacteroidetes,2FNC9@200643|Bacteroidia,4AKRD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 1.0 rbr 1.0 GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 771964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAGENEEWTQMYK MGYG000000099_00558 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,268QG@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478211 0 0 0 0 0 0 771891 0 0 0 0 0 0 670765 0 0 0 0 0 0 0 0 0 0 943969 863981 0 0 0 0 0 0 0 0 0 406097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAGENEEWTTDYPHFADVADQEGFPAIATMYR MGYG000000243_01523;MGYG000004797_00312 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1592@1|root,COG1592@2|Bacteria,4NH0J@976|Bacteroidetes,2FNC9@200643|Bacteroidia,22WSM@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Rubrerythrin 1.0 rbr 1.0 GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAGWGFDGLADDATAK MGYG000002926_01410 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 290334 0 0 0 0 422552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429373 0 0 314515 0 0 0 255539 0 335214 0 0 349111 0 0 568129 0 0 549516 511167 0 204024 0 0 0 0 0 0 0 0 419263 0 0 0 0 0 0 313519 668004 0 0 0 0 0 0 423036 235965 400556 549354 0 930314 0 392729 1157146 0 0 700060 762234 621384 550510 0 763226 0 0 0 0 956124 0 927774 784632 678875 0 0 0 933262 1126183 1224399 0 0 871743 0 0 809484 864254 1302502 520545 1065603 809593 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAIDQK MGYG000002528_02464 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,267YC@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gltA 1.0 - 1.0 1.4.1.13,1.4.1.14 1.0 ko:K00266 1.0 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 1.0 - 1.0 R00093,R00114,R00248 1.0 RC00006,RC00010,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fer4_20,NAD_binding_8,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate synthase (NADPH). | glutamate synthase (NADH). NADPH-glutamate synthase. | NADH-glutamate synthase. The reaction takes place in the opposite direction.-!-The protein is composed of two subunits, alpha and beta.-!-The alpha subunit is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.4).-!-The beta subunit transfers electrons from the cosubstrate.-!-The NH3 is channeled through a 31 A channel in the active protein.-!-In the absence of the beta subunit, coupling between the two domains of the alpha subunit is compromised and some ammonium can be produced.-!-In the intact alphabeta complex, ammonia production only takes place as part of the overall reaction.-!-Formerly EC 2.6.1.53. | A flavoprotein (FMN).-!-The reaction takes place in the direction of L-glutamate production.-!-The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2). 2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH. | 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH. 1.0 1.0 1.0 1.0 Nitrogen metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 116320 0 0 0 147573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324626 0 0 0 144458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAIVGGGGGGRPNMAQAGGK MGYG000002989_02299;MGYG000000806_01910 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3XYZ6@572511|Blautia 0.5 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 - 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 976273 0 0 0 0 0 -AAAAKPEDEKLAK MGYG000000233_02981;MGYG000002445_00877;MGYG000000255_00872 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1788@1|root,COG1788@2|Bacteria,1UYH2@1239|Firmicutes,24CPB@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit 1.0 gctA 1.0 - 1.0 2.8.3.12 1.0 ko:K01039 1.0 ko00643,ko00650,ko01120,map00643,map00650,map01120 1.0 - 1.0 R04000,R05509 1.0 RC00012,RC00131,RC00137 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconate CoA-transferase. - Glutarate, (R)-2-hydroxyglutarate, propenoate and propanoate, but not (Z)-glutaconate, can also act as acceptors. acetyl-CoA + trans-glutaconate = (2E)-glutaconyl-CoA + acetate. 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Styrene degradation 1.0 none 1.0 4349954 2231726 3419254 3233979 2084067 2013214 2568785 4455822 2934022 4571421 2254337 2767738 2039628 4047996 3266909 2219038 2666410 2003678 3296806 3511380 3103174 2733083 1352528 1845730 3641241 2603310 3043464 1441540 3261023 2879100 2014932 2937892 1925370 4940828 3663322 2607333 2411691 1680790 3733848 3102914 2582609 5706127 4542456 3126834 4660280 5162780 3473333 5475742 4380500 4065585 4608427 4979749 3960993 3241563 4226342 680959 3656300 3943830 2940957 2682570 738727 3504852 4462522 4037748 4223984 1144246 5285819 4000028 3044588 4641508 3872231 4428034 3616986 4270693 3690824 2440256 1750820 3185068 1913771 2499789 1079231 1717620 1219738 2697527 2505805 2565660 1401902 1525162 0 2268289 2241730 1730008 1946767 1017200 2406227 2264757 1574581 2371025 993802 1749756 2748744 2677316 2883344 1430069 2191334 1887950 1382750 1894376 1891989 3709901 2206739 1828663 2099350 1796548 2443357 2408182 2575568 1920961 1828757 2929177 3009733 3338357 2277880 3724877 2425972 2085736 1806338 2636471 2508490 2613436 2184535 1053664 2586343 2296960 1161882 3308542 304768 3685505 2369430 2355438 3090796 964942 3143886 1867383 2158740 2006179 2699975 3110749 2201888 1732254 0 2434041 615921 846369 907474 1387819 899053 863287 1207871 925613 987567 955400 1671060 1095323 1331879 1274307 878988 882680 714634 515685 758898 577967 809407 1000572 701175 1358035 1329565 1359173 1072413 469076 1237767 557394 1640064 1096431 1696595 1380909 1361035 1255779 1434733 1252131 -AAAAKWGLGNINR MGYG000000236_03540 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0280@1|root,COG0280@2|Bacteria,4NGX5@976|Bacteroidetes,2FMKY@200643|Bacteroidia,4AK60@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625,ko:K13788 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2061931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1749988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAALI(Xle->Val)DKDSAVELYAGFGK MGYG000000022_01359 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 646116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAALID(Asp->Asn)KDSAVEMYAGFGK MGYG000002040_01442;MGYG000002545_00188;MGYG000002274_02567 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1682368 0 0 0 0 115066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1748946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1542719 0 0 0 0 1210850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 722032 0 0 0 0 354610 0 0 0 0 158904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238558 0 0 0 0 529380 0 0 0 0 0 0 0 0 0 0 -AAAALIDKDSAVE(Glu->Gln)MYAGFGK MGYG000002040_01442;MGYG000002545_00188;MGYG000002274_02567 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1272669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408126 0 0 0 0 0 0 0 0 0 0 -AAAALIDKDSAVELYAGFGK MGYG000000022_01359 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116610 0 0 0 0 479876 0 0 0 0 0 0 0 168405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588410 0 0 0 0 592094 0 0 0 0 434387 0 0 0 0 88287 0 0 0 0 0 0 0 621452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 710560 0 0 0 0 897498 0 0 0 0 1064246 0 0 0 0 116915 0 0 0 0 604439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 440541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 932370 0 0 0 0 1090496 0 0 0 0 1972091 0 0 0 0 580998 0 0 0 0 471918 -AAAALIDKDSAVEM(Met->Xle)YAGFGK MGYG000002040_01442;MGYG000002545_00188;MGYG000002274_02567 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1069986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAALIDKDSAVEMYAGFGK MGYG000002040_01442;MGYG000002545_00188;MGYG000002274_02567 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 404978 0 0 0 0 0 868416 0 0 0 0 1080866 0 0 0 0 1061863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 960814 0 0 0 0 956260 0 0 0 0 749971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431018 0 0 0 0 0 1117770 0 0 410865 0 1172078 0 0 0 0 1233437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192365 0 0 0 0 0 292816 0 0 0 0 314354 0 0 0 0 290136 0 0 0 0 0 0 0 0 0 0 -AAAAM(Oxidation)EGPVYMR MGYG000000028_00572;MGYG000002528_00836 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Transketolase 1.0 tktB 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 957304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599321 0 0 0 0 0 0 0 0 0 -AAAAMEGPVYMR MGYG000000028_00572;MGYG000002528_00836 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Transketolase 1.0 tktB 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 996453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6456622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4380046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAMGDEVEIFALPISEGEKR MGYG000000045_01524 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG1440@1|root,COG1440@2|Bacteria 1.0 2|Bacteria 1.0 G 1.0 protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity 1.0 gmuB_2 1.0 - 1.0 2.7.1.196,2.7.1.205 1.0 ko:K02760 1.0 ko00500,ko02060,map00500,map02060 1.0 M00275 1.0 R11170,R11172 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.3.2 1.0 - 1.0 iEC55989_1330.EC55989_1672,iECIAI1_1343.ECIAI1_1550,iECO103_1326.ECO103_1669,iECO111_1330.ECO111_1934,iECO26_1355.ECO26_2139,iECSE_1348.ECSE_1627,iECW_1372.ECW_m1666,iEKO11_1354.EKO11_2279,iWFL_1372.ECW_m1666 1.0 PTS_IIB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphotransferase. | protein-N(pi)-phosphohistidine--D-cellobiose phosphotransferase. N,N'-diacetylchitobiose PTS permease. | D-cellobiose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N,N'-diacetylchitobiose(out) = diacetylchitobiose-6'-phosphate(in) + L-histidyl-[protein]. | D-cellobiose(out) + N(pros)-phospho-L-histidyl-[protein] = 6-phospho- beta-D-glucosyl-(1->4)-D-glucose(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS);Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 9323139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAANIVPN(Deamidated)TTGAAK MGYG000004828_01576;MGYG000002485_02480 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 658941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492624 0 264702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAANIVPN(Deamidated)TTGAAKAIGLVIPSLKGK MGYG000004828_01576;MGYG000002485_02480 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410775 0 0 0 0 0 0 0 576440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAANIVPNTTGAAK MGYG000004828_01576;MGYG000002485_02480 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3653980 6508843 8687046 0 6147523 11349256 5765418 0 3731639 14146903 10175351 5084645 8314079 4540235 0 12149556 11011687 0 3990925 3046713 5074493 13934807 0 10015308 3904900 3304999 4224987 0 4992437 6565095 9878917 5820264 10386987 3536332 3720629 3804931 3152486 9087550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAPAAAAPVAPTADPVIPK MGYG000000212_01006 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3XYZP@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1041218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAPAAAGAAAAAEEEKTEFDVILAEAGATK MGYG000003166_01197;MGYG000001300_02635 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 2745690 0 0 0 0 0 0 0 0 0 0 0 1788612 0 0 0 7733357 794283 7360445 0 0 0 785323 0 0 0 0 3787309 0 0 0 0 0 0 0 25885579 0 0 5757028 0 0 0 0 0 4649047 15692324 0 0 0 0 12221699 0 0 0 4785464 38336049 9535542 0 0 0 11877629 0 0 4836867 0 24929259 0 0 0 0 27402939 0 0 0 0 0 5162600 0 0 0 0 0 0 3007896 0 0 0 0 0 0 0 0 2048938 5304842 1139226 0 0 0 10516931 0 0 0 0 0 0 0 0 0 0 0 0 10118280 0 0 12393852 0 0 0 0 0 0 35079699 0 0 0 0 0 0 0 0 4151482 0 32850541 0 0 0 26541431 0 0 21313017 0 27989365 0 0 0 0 16163137 0 0 9999411 0 0 4867594 0 0 0 0 0 1262281 0 0 0 0 0 11202413 0 0 0 0 41182975 0 0 0 0 11803711 0 0 0 0 14662710 0 0 0 0 0 -AAAAPAAGGAAAPAEEEKTEFDVILADVGANK MGYG000003921_01314 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 173805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31210659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAPAAPAAPK MGYG000003166_01306;MGYG000003899_01745 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468637 0 532518 0 0 0 3075871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 868355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAPAVR MGYG000004797_01082 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 2DZSH@1|root,32VHS@2|Bacteria,4NYRA@976|Bacteroidetes,2FRXJ@200643|Bacteroidia,4AT0S@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 to other proteins from the same organism 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAPVAGGEPVKAPMPGNILDVK MGYG000003891_01453 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1460373 0 0 960429 0 1952381 0 0 0 0 1775376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAPVAR MGYG000004482_00849;MGYG000004276_00434 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,2N7T7@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-lipoyl like 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 183129 0 0 0 0 762190 0 0 0 0 1270506 0 0 0 0 1178094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769484 0 0 0 0 190926 0 0 0 0 703276 0 0 0 0 1142145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116619 0 0 0 0 0 0 0 0 0 465836 0 0 0 0 462172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAQTTDEANK MGYG000003683_00185;MGYG000003683_00184 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 E 1.0 ABC transporter, substrate-binding protein, family 5 1.0 dppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 165316 0 0 0 0 69240 0 0 101467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119360 0 0 0 0 262897 0 421728 979642 707978 438178 1444013 0 653317 0 0 706291 0 0 0 0 0 0 2055936 0 563335 0 628076 1168046 2581485 0 0 0 3081357 0 0 1924459 0 622566 0 0 0 0 1011023 0 293428 220280 159580 0 104085 0 175461 0 0 145863 0 0 0 0 0 0 0 0 308818 0 212683 77756 0 0 0 0 203741 0 0 85642 0 408268 0 0 0 0 171073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 240953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAQVK MGYG000002105_01537 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__SFJ001|s__SFJ001 sp004555865|m__MGYG000002105 1.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WG9P@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily 1.0 purB 1.0 - 1.0 4.3.2.2 1.0 ko:K01756 1.0 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 1.0 M00048,M00049 1.0 R01083,R04559 1.0 RC00379,RC00444,RC00445 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADSL_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adenylosuccinate lyase. succino AMP-lyase. Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole. (1) N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate. (2) (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamide + fumarate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1398587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAASLEMPLYR MGYG000001255_01646;MGYG000001300_01663 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 774724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAASLEPGDHGTTYGGNPFVC(Carbamidomethyl)AAVSK MGYG000000133_01201 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3XYZW@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 8.87 1.0 argD 1.0 - 1.0 2.6.1.11,2.6.1.17 1.0 ko:K00821 1.0 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00028,M00845 1.0 R02283,R04475 1.0 RC00006,RC00062 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetylornithine transaminase. | succinyldiaminopimelate transaminase. succinylornithine aminotransferase. | succinyldiaminopimelate transferase. Also acts on L-ornithine and N(2)-succinyl-L-ornithine. 2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L- glutamate 5-semialdehyde. | 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (S)-2- succinylamino-6-oxoheptanedioate + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Lysine biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 699507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692186 0 0 0 0 0 0 0 -AAAATALSAVK MGYG000004769_01749 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 2DBJA@1|root,2Z9JR@2|Bacteria,1VPE5@1239|Firmicutes,4H62X@909932|Negativicutes 1.0 909932|Negativicutes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1904647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2403233 0 0 0 0 1695681 0 0 0 0 988452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAVAVAAPAAGGEGAAAAEQTEFDVILK MGYG000000254_02576 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Marinifilaceae|g__Odoribacter|s__Odoribacter splanchnicus|m__MGYG000000254 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAVEGIKK MGYG000002960_01043;MGYG000003697_02080;MGYG000002293_01614;MGYG000002603_00267 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 CH 1.0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 - 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 257417 0 0 0 0 0 0 0 0 0 0 0 582457 84605 0 0 0 599124 0 0 0 0 62763 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 274929 0 0 0 0 261291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2199503 0 0 500215 0 0 0 0 896482 0 0 0 0 0 0 1274353 0 0 0 1431465 536509 1897429 0 0 0 2261345 0 0 0 0 573639 0 0 0 0 1469852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAVIDKDSAVELYAGFGK MGYG000001300_00243;MGYG000002641_00107;MGYG000002619_00445;MGYG000002223_01488;MGYG000002651_00051 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 880371 955512 1283749 1657868 345096 680829 926639 488027 1055685 727218 781722 583501 737821 805315 756596 738273 1142582 669824 1063220 823418 417858 742582 614415 796938 735462 872974 853841 461154 0 387323 932325 656952 1074394 1311936 349926 809528 591468 1137728 2031241 1485689 1472204 2184531 1691727 2800191 3397595 1363417 2180791 461440 1551352 2818542 1665590 2443370 2608128 1828308 3206368 543137 2545227 2226067 1014508 1927453 107367 1589033 2545649 2119337 2111771 437018 0 1444671 2522381 2137680 1305736 2110512 834832 1837956 1912899 1901569 475689 489940 364310 564587 482947 363884 581583 640509 495546 349913 794251 545562 646531 500176 553398 523700 258693 478911 312765 0 354502 121500 333584 213763 455883 625080 600290 590251 0 493386 722707 536460 289275 658796 666075 504516 628248 402498 1038590 1572922 1676937 991165 1226919 1522808 1965822 575889 1377578 745532 1254250 1383901 1840503 1516895 1110506 1239534 1219825 562320 1330135 1145209 1521096 1936035 987098 1614373 1281741 1213132 980831 615031 0 1452776 1788681 1545250 1331195 1521277 480624 1029582 1521022 1631822 672980 506130 509914 863453 0 256647 826234 471701 307911 692814 533340 289095 327854 615860 412952 547103 376828 0 153114 198363 968272 223379 0 466769 754674 549981 443976 0 0 0 283977 325996 0 611223 227295 565584 372778 315411 -AAAAVLGWER MGYG000004735_02276 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 S1 RNA binding domain protein 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 329707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1527082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAYLDIPLYR MGYG000001346_02829;MGYG000002717_02775;MGYG000001780_02258;MGYG000001661_02794;MGYG000003681_01100;MGYG000002455_05125 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 1002390 748883 808595 913356 587944 729399 1105329 1104395 1069848 1010415 1140835 1592671 0 915646 0 763481 870157 0 1030589 872444 966342 770109 0 879258 0 882769 813688 0 875288 1433848 807517 808880 796972 1209721 1080821 991526 1024527 703023 823831 1328123 1162189 1563316 1918707 1660790 975132 1438571 933978 1280996 1405094 4069542 0 1523206 0 1486372 1240745 0 931868 1157380 1440049 2164407 0 1332593 0 1271031 1154661 0 1253109 1447538 1299820 1764750 1434008 1416186 1115498 930162 866789 1312753 1351273 904687 1264178 771150 1388145 1230703 1424896 1673677 1041858 1206129 1579985 2111429 0 1181405 0 1338812 654123 0 1084840 1255512 1172971 1039620 0 1201010 0 1037064 0 0 1155624 1409868 1295376 946933 1009487 806507 1181177 859376 911030 1124182 864096 588861 1100332 751802 897654 786292 745689 917098 814169 691541 846304 1431425 0 724209 0 786285 645249 0 839863 692266 975462 1033183 0 0 0 981751 941819 0 832670 1158353 608206 772121 1050513 1093425 992761 850880 745225 707640 460107 493647 435317 770259 1212086 791657 475985 936800 759473 502336 2196650 992475 0 426823 0 225738 567780 0 280634 673005 450532 366690 0 710775 0 648496 410295 0 638847 1079627 461874 768875 398632 1007546 797481 312579 718923 552611 -AAAAYLDV(Val->Xle)PLYR MGYG000001313_02613;MGYG000000224_01011;MGYG000000105_02944 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1091076 0 0 0 0 0 0 0 0 0 1320826 0 1315964 0 1236466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 831998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAYLDVPLYR MGYG000001313_02613;MGYG000000224_01011;MGYG000000105_02944 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 255791 0 0 0 0 168203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300886 0 0 0 0 0 504873 0 0 0 255302 0 0 192372 0 0 0 0 1735472 1121922 0 0 0 0 1838820 2363617 0 1776064 0 1719572 0 0 1510544 998799 1224222 0 0 1404089 1786239 0 0 0 1678446 1496067 1365410 0 1786032 0 1784762 0 0 3525905 1518376 0 1448036 0 461111 387367 0 0 0 0 343245 465376 0 269511 0 266550 0 0 427282 642406 306233 0 0 339925 607602 0 0 0 544782 277100 459174 0 258851 0 147885 0 0 837972 482187 0 497571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAAYLNIPLYR MGYG000001364_02911 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius|m__MGYG000001364 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 700116 0 0 0 0 0 0 0 3805746 0 0 0 0 5950170 0 0 0 0 3682429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180927 0 0 0 0 379479 0 0 0 0 387661 0 0 0 0 0 0 0 0 0 0 -AAAAYVGTVIAK MGYG000000179_04584;MGYG000000198_04903 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,2206V@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1229683 0 0 0 0 0 0 0 618243 363342 0 0 0 0 545955 0 0 0 307822 825780 874708 0 0 0 340683 670459 793412 0 0 616262 0 0 0 0 0 0 813675 0 968253 0 217873 0 0 0 0 846403 834638 1092782 0 472803 0 0 753164 0 412604 0 543596 959794 638694 0 0 0 592087 944401 1027228 0 0 461940 231744 256802 346636 0 0 0 849691 281669 1171819 0 381954 0 0 0 0 692712 990899 843451 0 505595 0 0 974308 0 772728 0 740499 1008357 1348208 0 0 0 165050 786263 1114059 0 0 1283806 401321 453100 624493 0 0 0 788400 694333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3477086 0 1295229 0 0 0 0 2397993 2071621 2162518 0 1767396 0 0 3051309 0 2069486 0 2217831 3145654 2639245 0 0 0 2001006 2564055 2992762 0 0 1744230 1150638 973770 1275481 0 0 0 1583718 1073549 -AAAC(Carbamidomethyl)EAVGR MGYG000003291_01608;MGYG000003166_00738;MGYG000001300_02373;MGYG000000022_01425 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3WK2P@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 - 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 178244 0 0 0 508594 250664 0 0 0 158109 277165 0 0 186448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217570 270704 0 0 0 0 0 0 105104 0 0 310846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115401 385098 490769 0 0 156782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1376516 1289871 0 1198597 1258997 1404271 0 0 1134988 0 0 1076714 1312689 896343 0 1372258 1494410 1217829 1942602 0 1693741 370222 2947485 746076 0 0 3925159 955315 1080372 2210572 597832 1180394 0 0 0 0 2236112 0 0 0 0 226867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380170 0 319641 0 0 0 0 0 0 0 0 -AAAC(Carbamidomethyl)ESFGYNEDAIVSSDVIGMR MGYG000000198_04065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 776023 0 0 819883 0 275591 0 0 0 0 0 0 0 0 325434 0 0 0 483913 847248 0 324569 0 201158 0 696240 513407 0 1168391 1028266 0 0 0 0 0 637875 696263 0 267274 0 0 192762 0 0 0 0 0 0 0 0 0 0 323435 0 0 0 0 228481 0 0 0 0 0 348007 267080 0 282524 0 0 0 0 0 0 206340 228609 0 767078 0 0 401246 0 0 0 0 0 0 0 0 0 0 609808 0 0 0 319130 616139 0 287345 0 0 0 796345 660718 0 707681 671373 0 0 0 0 0 654540 590833 0 0 0 0 258284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106341 379940 0 0 0 0 0 679795 1479195 0 174298 0 0 124319 0 705525 0 0 0 0 0 0 0 0 170365 0 0 0 1999059 127249 0 4853349 0 264688 0 169417 16699150 0 3694606 0 0 0 0 0 0 238802 650295 0 -AAAC(Carbamidomethyl)FLIR MGYG000002753_00171 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-103|s__|m__MGYG000002753 1.0 COG4716@1|root,COG4716@2|Bacteria,2GKZ8@201174|Actinobacteria,4CYZK@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 S 1.0 MCRA family 1.0 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 1.0 none 1.0 700362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 779321 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456771 0 0 0 0 0 0 0 0 0 0 408665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAC(Carbamidomethyl)FLVR MGYG000004785_01095;MGYG000000231_02045;MGYG000004733_00873;MGYG000000251_00145;MGYG000000249_02121;MGYG000002186_00911;MGYG000000242_03073;MGYG000000216_00347;MGYG000000212_00918;MGYG000001338_00189;MGYG000000187_00790;MGYG000001698_00562;MGYG000002517_00467;MGYG000000133_01077;MGYG000001185_00828;MGYG000000271_02405 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia 0.5 186801|Clostridia 1.0 S 1.0 Myosin-crossreactive antigen 0.625 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 1.0 none 1.0 941030 0 1268165 590772 1720620 1308942 0 1103003 0 0 2341389 0 1461486 864493 0 1548335 0 0 0 0 0 1222108 0 597658 1211258 692366 0 0 826137 0 708616 1238920 796641 0 133393 0 490149 988126 345623 0 413698 210661 0 0 0 419381 0 0 0 0 0 259218 0 0 0 0 0 0 0 0 0 0 99180 133036 0 0 408143 0 0 0 184667 0 285246 0 171024 0 530745 0 848817 609287 371433 528889 0 526314 0 0 525243 0 852154 680150 0 776638 0 0 0 0 0 757703 0 261224 622971 569857 0 0 643206 0 564623 725877 905704 0 471362 0 123550 727442 836724 0 748541 964752 1125777 803326 0 781548 0 0 685301 0 574683 844511 0 1324301 0 0 0 0 0 912165 0 478980 529333 0 0 0 1010920 0 1965840 974175 1006919 0 771931 0 804335 1025943 390418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527832 441995 449062 0 0 0 0 0 0 0 0 0 0 0 0 -AAAC(Carbamidomethyl)GGVTTIFDYPVQHK MGYG000002528_01045 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 PFAM amidohydrolase 1.0 hydA_1 1.0 - 1.0 3.5.2.2 1.0 ko:K01464 1.0 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 1.0 M00046 1.0 R02269,R03055,R08227 1.0 RC00632,RC00680 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_1,Urease_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 dihydropyrimidinase. hydantoinase. Also acts on dihydrothymine and hydantoin. 5,6-dihydrouracil + H2O = 3-(carbamoylamino)propanoate + H(+). 1.0 1.0 1.0 1.0 Metabolic pathways;beta-Alanine metabolism;Pyrimidine metabolism;Pantothenate and CoA biosynthesis;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 197885 0 433868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110964 0 455204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 425256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1144700 0 466963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAC(Carbamidomethyl)NIVPN(Deamidated)STGAAK MGYG000003355_00996;MGYG000001299_00204 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 0.5 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 648499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1604786 0 0 0 0 452263 -AAAC(Carbamidomethyl)NIVPNSTGAAK MGYG000003355_00996;MGYG000001299_00204 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 0.5 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 518381 0 0 0 0 361133 0 0 0 208012 0 0 0 0 0 0 0 0 474010 286330 168225 0 0 0 0 0 0 0 0 0 0 0 0 272332 319564 289581 0 2823116 2038721 840165 2625583 1180276 1587704 2715976 3037177 2153800 2198368 978822 1101017 0 1730879 0 0 0 0 1407591 2471653 1705563 970382 0 2353203 0 2046653 2724685 0 2861304 0 1952416 0 931931 2849235 3155158 2655990 2527159 979686 742668 917715 392548 617603 0 364718 607868 890367 339903 634186 464258 593443 0 553185 0 0 0 0 1108494 880713 556762 788549 0 330574 0 713534 857686 0 751233 0 311356 0 574281 1022099 905034 565317 691313 501509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1580495 2623077 9855997 2129900 632814 12685454 3549151 2461632 1715703 2759881 2383801 1811216 0 3404852 0 0 0 0 1668801 554020 2318346 10798161 0 12097834 0 2406635 1974263 0 3572205 0 4616534 0 20059372 2429093 2008920 2435272 1212585 6509163 -AAAC(Cys->Ser)ESFGYNEDAIVSSDVIGMR MGYG000000198_04065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 907449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAACESFGYNED(Asp->Trp)AIVSSDVIGMR MGYG000000198_04065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 1348023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 688293 0 0 0 0 1189551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 810487 0 0 0 0 807485 0 0 394643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225168 0 0 0 0 0 -AAACNI(Xle->Tyr)VPNSTGAAK MGYG000003355_00996;MGYG000001299_00204 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 0.5 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 602390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 526875 0 0 0 0 597772 0 0 698516 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663654 0 0 0 0 1072768 0 0 630798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1758850 0 0 0 0 1013277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3952983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3301715 0 0 0 0 2919300 -AAADAAKTEADKAVAEASAVK MGYG000002455_05079 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG3883@1|root,COG3883@2|Bacteria,4P07U@976|Bacteroidetes,2FN9Y@200643|Bacteroidia,4APBT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 nuclear chromosome segregation 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Collagen,DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 737248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5834560 0 0 0 0 -AAADAAVQFISGEEVDAK MGYG000000242_00891 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,21Z0Q@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 K 1.0 PFAM regulatory protein GntR HTH 1.0 - 1.0 - 1.0 - 1.0 ko:K00375 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2,GntR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1098607 0 0 0 0 420342 0 0 0 0 347514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239125 0 0 0 0 0 0 0 0 0 195165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 693574 0 0 0 0 745094 0 0 0 0 1042929 0 0 0 0 0 0 0 0 0 0 -AAADALFAAGK MGYG000003166_02177;MGYG000001300_01133;MGYG000003291_01773 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WHFT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner 1.0 valS 1.0 - 1.0 6.1.1.9 1.0 ko:K01873 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03665 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 GH5_11 1.0 valine--tRNA ligase. valyl-tRNA synthetase. - ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 120523 308296 329862 0 0 250502 0 0 114785 0 471239 198626 0 0 0 0 0 0 551068 428970 0 122841 0 198039 0 334019 0 0 0 0 0 315353 0 0 0 0 121043 150712 647041 899321 888373 0 0 912577 0 0 752475 0 526469 962856 0 0 0 0 0 0 937449 985749 0 685907 0 1082402 0 509654 0 0 0 0 965141 756639 927506 0 0 0 686870 723191 303718 295869 428646 0 0 291627 0 0 295250 0 516952 535222 0 0 0 0 0 0 346092 389000 0 118215 0 173679 0 261532 0 0 0 0 251302 258767 119352 0 0 0 206631 314393 365037 299836 879639 0 0 647823 0 0 327356 0 588459 612145 0 0 0 0 0 0 238738 376392 0 646440 0 685761 0 374560 0 0 0 0 672545 505650 771621 0 0 0 300858 721687 467182 550359 309746 0 0 735176 0 0 411407 0 302084 384113 0 0 0 0 0 0 581354 512761 0 475179 0 923355 0 527598 0 0 0 0 269554 322728 375658 0 0 0 508833 1687923 -AAADAMQDGDVILLQNTR MGYG000000080_03114 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3352533 0 0 0 0 0 0 0 0 0 -AAADDAETIC(Carbamidomethyl)GEDYWPLPSYSK MGYG000001300_00352;MGYG000002040_00733;MGYG000000022_01091 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 0.6666666666666666 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 GABAergic synapse;Necroptosis;Glyoxylate and dicarboxylate metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 566356 264383 0 0 0 0 257227 0 0 0 0 485334 0 0 0 0 612945 325970 0 0 0 0 0 400586 232982 527561 0 0 0 0 455615 0 0 0 272441 311637 536736 0 590965 656978 0 0 768765 0 689226 0 0 713632 0 759021 0 0 646481 877488 874675 797944 0 0 1092504 0 956550 840109 562150 881572 0 0 0 0 0 0 0 0 0 421724 0 0 0 0 0 0 224144 0 0 0 0 0 0 291863 0 0 0 272877 127476 203459 0 0 0 0 0 0 0 425342 0 0 0 0 0 0 0 0 0 161358 500048 0 745928 453646 0 0 619238 0 520939 0 0 529200 0 563305 0 0 587609 248095 575684 503654 0 0 243491 0 435904 602181 466355 381693 0 0 0 0 531717 0 0 0 531792 465862 0 0 0 0 0 0 84190 0 0 0 0 0 0 0 0 0 0 472891 0 0 0 0 544388 0 0 0 0 530754 0 0 0 0 0 0 0 0 0 179092 -AAADDAETLC(Carbamidomethyl)GEDYWPLPSYSK MGYG000003291_00218;MGYG000003899_00843 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 1.0 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 GABAergic synapse;Necroptosis;Glyoxylate and dicarboxylate metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303924 0 0 0 0 0 0 0 0 0 0 482564 0 0 0 0 0 0 0 0 783219 0 0 0 0 0 0 471288 0 459932 0 0 0 0 0 0 0 0 524185 0 0 546139 733428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 624471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADEAAAPAVVEEGGLHK MGYG000003693_02590 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 828560 0 0 0 0 1847266 0 0 0 0 1112199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADEEKEPAKK MGYG000000280_00174 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__AM51-8|s__AM51-8 sp003478275|m__MGYG000000280 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,27I7R@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADEHHVQYEER MGYG000000133_02652 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,27I57@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 tRNA synthetases class II (D, K and N) 1.0 lysS 1.0 - 1.0 6.1.1.6 1.0 ko:K04567 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03658 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DUF2156,tRNA-synt_2,tRNA-synt_2_TM,tRNA_anti-codon,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine--tRNA ligase. lysyl-tRNA synthetase. - ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517531 0 757192 0 0 0 949630 0 0 755942 0 647623 0 0 0 0 0 0 0 0 1250022 0 0 0 0 753286 0 0 0 0 0 0 1691749 0 0 1261687 580546 751737 -AAADEWDER MGYG000002506_00360 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 291QA@1|root,2ZPAE@2|Bacteria,1RI2H@1224|Proteobacteria,1S689@1236|Gammaproteobacteria,3XPRZ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 MsyB protein 1.0 msyB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 - 1.0 ko:K12147 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 MsyB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 773017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 744328 0 1104428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 514041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604187 0 363744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 548383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227751 0 483717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADGC(Carbamidomethyl)PTAPEVLAK MGYG000002552_01042 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp000436535|m__MGYG000002552 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 614727 0 0 0 0 463504 0 0 0 0 579609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1038724 0 0 0 0 925383 0 0 0 0 1143372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 757789 0 0 0 0 480659 0 0 0 0 385134 0 0 0 0 0 0 0 0 0 0 -AAADKAGVNVK MGYG000001060_01648 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister hominis|m__MGYG000001060 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,4H3VQ@909932|Negativicutes 1.0 909932|Negativicutes 1.0 G 1.0 sugar-binding domain protein 1.0 rbsB 1.0 - 1.0 - 1.0 ko:K10439,ko:K17213 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212,M00593 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 868595 0 0 0 0 394035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADKAVADAK MGYG000002478_01081 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 5348952 4662430 5108485 9597658 7817546 6856743 6377108 0 6645392 6068871 0 6927671 10165920 4582508 0 13336360 9317951 9587995 9359437 6625683 5490413 0 6323513 5123369 5701862 5588351 6649266 8360777 5507132 7941239 0 7119878 4412900 0 5739340 6864245 5423283 4659211 215486 0 0 228927 116920 0 0 0 0 0 0 0 88473 195051 0 242537 286315 108565 0 0 0 239664 0 0 128358 0 0 0 0 216819 0 287261 144440 0 71161 159096 156849 52579 803249 1541333 1082627 1422775 1014341 900509 401567 0 812251 0 0 773551 1671895 972558 0 1342577 1040696 319811 1255203 1136490 1316537 1097951 642422 745656 889536 1085438 1284130 1677821 1009192 829102 0 834285 767472 0 1770821 1367808 1404985 1043639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325272 147558 102647 220073 220472 172671 119225 0 288355 167457 0 150274 348423 727422 0 255876 221251 547813 263105 265527 767901 194513 395347 289986 408611 305051 203335 199276 208368 0 0 190378 86520 0 400330 278121 119262 312607 -AAADKAVADAKAEAIK MGYG000002478_01081 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 3379548 5866319 6618855 4120322 8709420 5182787 2580135 0 3261236 4013850 0 0 10031994 4349659 0 9232052 5914018 5344374 5677653 3871936 3873754 0 3296506 4048154 3915497 4182576 2995089 3286894 2758432 4340221 0 7051009 6358811 0 5406424 0 3843796 5826132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 866905 1581975 1236289 1063424 1376097 964559 0 0 0 1184594 0 0 2324207 786511 0 1656352 82172 110978 1055990 914198 681854 1040881 78882 697427 0 722875 950710 0 914156 738796 0 1164936 1065460 0 841745 0 89544 622313 0 0 0 0 0 0 0 0 0 0 0 0 129837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374460 0 0 0 0 0 0 0 359944 0 0 0 0 313193 0 0 0 0 0 58583 0 0 0 0 0 0 0 0 0 0 -AAADKAVAE(Glu->Asp)AK MGYG000002560_04324 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp902388365|m__MGYG000002560 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1185512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADKFLETK MGYG000002492_01331;MGYG000000398_00301 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 135008 164266 125778 123948 212687 117677 47161 149188 131999 0 224405 233736 253819 85642 135845 182287 0 538726 72017 100593 163296 134064 325249 0 149341 180694 84139 398822 0 100704 84609 272095 0 62276 152637 74424 152411 165580 793162 698953 3790394 822806 1759017 512295 1038244 736699 926745 0 1683710 0 1400175 652128 611837 1220240 0 6905602 545077 806877 987568 418710 4307091 550199 728759 733278 749168 5918432 0 724363 2075897 1093246 0 858270 794016 876981 0 4012417 0 1966463 9303990 1628222 3420056 2119321 2014300 1770349 1990994 0 0 2194859 3717223 1880746 2144879 4323668 0 2089054 1846644 1846074 1740441 0 0 0 0 1925079 0 0 0 2240617 3547620 0 8718200 2361711 2211292 1560841 0 0 295620 124307 0 708799 98383 0 81909 0 518311 0 452265 227871 148274 0 275156 181524 0 301466 218896 0 165484 0 139160 76677 101622 257734 0 99447 0 83455 150623 65821 78158 229051 0 301903 0 551500 0 429417 513910 96592 97022 0 84468 0 72654 0 133594 0 0 575516 103476 231139 0 0 183436 74018 146727 0 140979 124701 144546 146699 484105 132869 0 0 1168869 134548 0 101025 0 131817 0 0 -AAADKFLETKDDTK MGYG000002492_01331;MGYG000000398_00301 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 210951 0 497769 310936 228630 0 0 0 0 429648 526440 423907 296168 0 392389 221218 0 769423 0 0 0 406741 567031 214765 587167 317540 0 578879 0 331033 0 0 202174 0 384558 0 0 321055 429141 214836 1035902 353377 1162170 438524 0 248505 0 380894 1017564 323701 656298 308876 260178 457292 0 1071653 211553 0 0 243982 486909 434874 282954 321058 0 1196801 0 325774 437397 0 2392784 409221 444902 0 395807 1228401 1776975 1696822 7225770 1548795 2636353 1319595 0 1764245 0 1707473 2469336 2125611 3333848 1518205 1494347 3439986 1527710 1220105 1735757 0 0 1393596 1927319 1304353 1688038 1783135 0 2510570 0 1808178 2719123 0 5932657 1762331 1999002 0 1592270 6412781 0 0 168207 0 0 0 0 0 0 0 170016 0 0 0 274483 0 0 0 0 0 0 0 221130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163794 0 0 0 0 0 0 0 0 0 0 350597 0 0 0 0 0 0 217871 0 0 0 0 0 0 0 0 -AAADKFLETKDDTKANVEPTTALIAELEK MGYG000002492_01331;MGYG000000398_00301 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1397043 0 0 0 0 0 0 0 0 0 920326 0 0 881673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1739914 0 0 0 0 1241381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADLLVLAYHR MGYG000003695_00289;MGYG000004558_01494;MGYG000000249_00466;MGYG000003581_01363;MGYG000002279_00355;MGYG000002992_01118;MGYG000001338_01660;MGYG000000038_02127;MGYG000000184_00391 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily 1.0 rfbB 1.0 - 1.0 4.2.1.46 1.0 ko:K01710 1.0 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 1.0 M00793 1.0 R06513 1.0 RC00402 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 dTDP-glucose 4,6-dehydratase. - - dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. 1.0 1.0 1.0 1.0 Acarbose and validamycin biosynthesis;Biosynthesis of vancomycin group antibiotics;Polyketide sugar unit biosynthesis;Streptomycin biosynthesis 1.0 none 1.0 748334 440342 415592 405102 269376 479775 0 858522 499561 354595 672616 0 416769 408837 0 373192 760174 187884 1026264 769964 554429 525295 73016 276560 0 561056 541294 186248 245765 375995 0 447166 297131 531869 668527 295661 424566 330446 350022 491697 471019 422816 1563365 204130 0 400461 483946 433672 825875 0 526451 341667 526943 312051 143523 1126279 257679 519010 408914 239144 512978 339343 485613 352517 304639 698666 285809 268642 0 860702 494086 408469 395954 400179 320333 786852 805070 732674 365600 967335 360561 288435 0 787653 345704 658702 451767 0 577850 764529 1056113 600100 551977 150243 1249458 1161410 671896 565731 332713 409951 1131215 980296 1170131 411645 714638 749813 0 650600 611383 1021020 1307945 423980 773268 460771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADLNYTLR MGYG000002438_02346 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG3015@1|root,COG3015@2|Bacteria,4P5SI@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 MP 1.0 NlpE N-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NlpE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1275302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1064042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2003698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADLQLQGVPAMFVN(Deamidated)GK MGYG000002494_01991;MGYG000002534_04778 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Thiol disulfide interchange protein 1.0 dsbA 1.0 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0016853,GO:0016860,GO:0016864,GO:0042597,GO:0044464,GO:0140096 1.0 - 1.0 ko:K03673 1.0 ko01503,map01503 1.0 M00728 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03110 1.0 - 1.0 - 1.0 - 1.0 DSBA,Thioredoxin,Thioredoxin_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cationic antimicrobial peptide (CAMP) resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 643688 1068823 1009827 601595 998361 1766710 828662 0 0 1047102 0 733030 0 1155983 0 0 1537569 0 1216809 638619 0 1693200 0 1332391 1252623 456955 740700 0 1897019 1183107 447314 935932 1162151 0 0 0 676002 620504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2937786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADLQLQGVPAMFVNGK MGYG000002494_01991;MGYG000002534_04778 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Thiol disulfide interchange protein 1.0 dsbA 1.0 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0016853,GO:0016860,GO:0016864,GO:0042597,GO:0044464,GO:0140096 1.0 - 1.0 ko:K03673 1.0 ko01503,map01503 1.0 M00728 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03110 1.0 - 1.0 - 1.0 - 1.0 DSBA,Thioredoxin,Thioredoxin_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cationic antimicrobial peptide (CAMP) resistance 1.0 none 1.0 0 371983 0 255685 0 375852 0 0 0 241148 0 0 0 0 0 0 0 0 202768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207754 0 852159 732667 582370 0 857400 644775 0 0 801337 0 0 0 0 0 0 784668 0 723002 0 0 1195851 0 884414 0 0 0 0 928415 0 0 0 598524 0 0 0 0 840813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359190 0 307081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADPFAELYK MGYG000002528_02607 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG5263@1|root,COG5263@2|Bacteria 1.0 2|Bacteria 1.0 S 1.0 dextransucrase activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Big_2,Big_3,Big_4,CHAP,CW_binding_1,DUF5011,Esterase,Glyco_hydro_70,LRR_5,Lectin_C,Lyase_8,Lyase_8_C,Lyase_8_N,SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 264705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193512 0 0 266538 0 0 0 0 0 0 0 1316711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 758850 0 0 0 0 0 0 0 385377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1911495 0 0 239968 0 0 0 0 0 0 0 704246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1969498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADTAAAETK MGYG000000074_01658 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG2152@1|root,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,2FPFW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 COG NOG16664 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1080 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 110547 95395 237647 386144 513161 576918 0 391161 356536 511735 416953 390438 716189 0 725214 145310 463026 0 376884 498156 315083 0 0 136360 748876 329983 351345 0 268342 225747 331600 747214 242961 0 375190 466836 417056 383518 1597864 1255221 2096595 2677601 2028781 2001605 0 2191712 1970566 2008101 1685155 2494326 1401308 0 2111024 1535113 2055704 0 2621110 2673470 1975906 2082519 0 1874388 2207663 2006625 2196035 0 2123387 2666517 1670237 2174586 1768584 0 1510574 1224512 1922233 1364044 792897 0 432707 1478091 164977 877126 0 1209077 257417 935483 443573 650984 746166 0 1031125 921005 743476 0 216170 1097034 773768 1592451 0 639617 869514 1064416 1134664 0 555264 624491 297203 915036 727780 0 1110508 414181 786618 434077 1885301 1662597 1535469 0 1596386 1954103 0 1966438 2404771 1970293 1159625 1657440 1292489 0 1778154 2012731 1903425 0 2669740 2434200 902013 1838650 0 1668320 2787467 2985131 2174445 0 2163660 1916139 1295485 1660954 1629853 0 2076331 1047728 1924512 1562357 3166602 3532385 2835613 5049615 4726534 3590342 0 2397661 3724936 3388354 3082192 3136856 6220237 0 3320602 3300148 2928532 0 5848387 4637752 2987010 3481129 0 4914127 4031788 6889888 3637558 0 3301629 5020805 3940082 3596895 3592476 0 6941527 5630711 5765625 4492461 -AAADTESEKLGTLDQGTVVTR MGYG000002517_01751 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG3103@1|root,COG3103@2|Bacteria,COG4991@2|Bacteria,1USNV@1239|Firmicutes,24DRI@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 Bacterial SH3 domain homologues 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SH3_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235644 0 0 1111418 0 0 0 1395287 1135048 0 0 0 0 1302083 1447111 0 0 0 0 0 0 0 0 0 1254363 1052897 1168945 0 0 919764 0 0 0 1106287 1235183 894021 1472344 0 651666 0 0 0 0 0 0 504728 844624 0 0 0 0 862147 1072345 0 0 0 0 0 0 0 0 0 586097 635461 805575 0 0 734718 0 0 0 593758 665265 748807 1466034 0 -AAADVGAPYIEIHTGC(Carbamidomethyl)YADAK MGYG000002494_04100;MGYG000002534_03650 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,3XP85@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate 1.0 pdxJ 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.0 2.6.99.2 1.0 ko:K03474 1.0 ko00750,ko01100,map00750,map01100 1.0 M00124 1.0 R05838 1.0 RC01476 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iAF1260.b2564,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 1.0 PdxJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyridoxine 5'-phosphate synthase. pyridoxine 5-phosphate phospho lyase. In Escherichia coli, the cofactor pyridoxal 5'-phosphate is synthesized de novo by a pathway that involves EC 1.2.1.72, EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5.-!-1-Deoxy-D-xylulose cannot replace 1-deoxy-D-xylulose 5-phosphate as a substrate. 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432911 0 0 0 781939 0 0 0 0 0 0 0 0 0 0 630634 0 0 0 0 964357 0 464039 572977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADVYM(Oxidation)FAN(Deamidated)DQLEPLIK MGYG000002492_00484 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC transporter, solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADVYM(Oxidation)FANDQLEPLIK MGYG000002492_00484 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC transporter, solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADVYMFANDQLEPLIK MGYG000002492_00484 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC transporter, solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 539035 0 0 0 0 0 0 0 0 0 499756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134425342 0 0 0 0 12346821 0 0 0 0 130719313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20486343 0 0 0 0 53937645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3872040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADYFGLPLYR MGYG000001302.1_00358 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,22U9M@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 126441 0 0 0 0 302288 0 0 0 0 266431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585538 0 0 0 0 446859 0 0 0 0 491586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 916179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAADYFGM(Oxidation)PLYR MGYG000001420_02263;MGYG000002203_01744;MGYG000002082_02009;MGYG000000003_00610;MGYG000000074_00749 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,22U9M@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 504970 0 0 0 272289 0 0 0 237727 0 0 0 316546 0 0 0 0 0 0 409102 0 0 0 0 0 371885 0 0 0 0 0 0 0 0 0 0 238386 0 0 0 0 0 0 0 0 0 660862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139528 0 0 0 0 0 0 0 0 0 0 186375 0 0 0 0 0 242631 0 0 0 245359 0 0 0 247907 0 0 0 0 0 0 298521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 510074 0 222037 0 0 0 817956 0 0 0 419117 0 0 0 555396 0 0 0 0 0 0 299141 0 0 0 0 0 455012 0 0 0 0 0 0 0 0 0 0 364314 0 637458 0 0 0 683916 0 0 0 893343 0 0 0 1124551 0 0 0 0 0 0 1229153 0 0 0 0 0 815897 0 0 0 0 0 0 0 0 0 0 1079241 0 -AAADYFGMPLYR MGYG000001420_02263;MGYG000002203_01744;MGYG000002082_02009;MGYG000000003_00610;MGYG000000074_00749 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,22U9M@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 2880556 2992618 2014045 3616447 2010927 2626508 2884742 0 3311450 3603179 919661 4179778 2571608 2504857 3224531 2061663 3370466 0 4342551 3021406 3191736 2110833 0 2984581 2928422 3017993 3741592 0 2759441 6166898 2296809 3020433 1839945 0 2372382 3408139 3527803 1199050 2595907 1956710 3360092 3856683 2893340 2597902 2089675 2899661 2146126 3736778 2823836 3518908 2387543 3371879 4546781 2951667 2778648 0 4831515 4599774 4240981 3305623 0 2394560 3280413 3481422 2937355 0 2817353 3568630 1873912 3673301 2543626 2255065 2376242 2417321 2752697 2611181 1714017 999272 613077 779138 1398936 375421 458613 620362 2392770 645888 705453 940809 760930 445292 519985 0 1233320 0 638031 672177 2593311 535541 0 515911 383636 427014 400485 0 1099503 564760 469197 369585 611034 784783 281373 1900724 691111 330936 1847701 1315826 1644932 1410806 1775930 1907116 2623167 1879947 1743698 1968593 988989 2289117 1700025 2343690 2289056 1734937 1325954 0 2284524 1808513 2321093 906222 0 917636 2831717 2417229 1931190 0 1414645 1932444 1183771 1567031 1928884 1365496 1687843 2019917 2778110 979553 4210874 4593542 1259641 10310748 10734566 3075145 1369697 3388868 3422601 1122796 1592052 2514391 12703900 867458 124061 5197986 1732487 0 10247431 15604284 1403246 6399584 0 7422721 3573667 9484733 4624958 0 8187441 12069569 3808809 7874989 1548495 0 6129096 3545693 7263310 5083889 -AAAEAAAAQK MGYG000000003_00520;MGYG000003279_02451 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1686008 829395 204577 1236256 0 387738 844822 354465 1421757 897820 175576 976157 394015 0 1616957 406030 772549 0 1461250 282860 1597250 307676 0 870627 1030748 1192730 1567371 0 1015455 1350857 0 0 401487 55198 915152 1331529 1202942 335402 333620 230259 411720 425584 0 405100 327939 424416 380702 0 473270 910610 272935 0 428867 268698 317328 0 602589 385805 361435 407259 0 580068 306730 264760 402182 0 400535 410264 0 0 222742 0 275026 258857 527911 308589 1084827 386123 670226 564413 0 159685 510872 720125 541395 964659 255115 203955 391067 0 657236 424512 681167 0 571076 1158283 1269891 284790 0 793198 771164 807808 759651 0 362665 530238 0 0 884237 1519987 883440 1315341 566681 596305 181352 94128 45047 395566 0 153026 909430 196977 486957 161369 95575 121457 0 0 0 241309 208761 0 370519 318396 0 187759 0 304378 77251 0 148240 0 150193 0 0 0 54061 124760 177049 134083 193254 89711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEAAEAPKAE MGYG000004487_00048;MGYG000002720_01558;MGYG000002090_00804 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG2768@1|root,COG2878@1|root,COG2768@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,2N6NY@216572|Oscillospiraceae 0.6666666666666666 186801|Clostridia 1.0 C 0.6666666666666666 Putative Fe-S cluster 0.6666666666666666 rnfB 0.6666666666666666 - 1.0 - 0.6666666666666666 ko:K03616 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 ko00000 0.6666666666666666 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_13,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 none 1.0 859406 653818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 952454 0 0 0 0 0 0 0 0 632210 0 0 0 0 0 0 0 1017215 0 0 726574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEAAEGAEE MGYG000000802_00126;MGYG000001636_01005;MGYG000002775_01401;MGYG000003122_01642;MGYG000002050_00255;MGYG000002947_00311;MGYG000003274_00534;MGYG000003266_00528;MGYG000002961_01014;MGYG000004681_00342 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CWB2@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 - 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 773311 0 1142395 0 0 1011557 0 0 0 0 0 0 0 0 0 0 0 0 327520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 595366 0 279934 0 0 153321 0 0 0 0 0 0 0 0 0 0 0 0 248021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164919 0 461190 0 0 799664 0 0 0 0 0 0 0 0 0 0 0 0 352595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2179666 0 1911632 0 0 3009442 0 0 0 0 0 0 0 0 0 0 0 0 1285178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 129122 0 591850 0 0 407976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEADIAQER MGYG000004866_01541;MGYG000001627_00734;MGYG000003937_00315;MGYG000000724_00927;MGYG000001157_02268;MGYG000000573_01525;MGYG000000084_01366;MGYG000003921_00616 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,3WIRW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) 1.0 atpF 1.0 - 1.0 - 1.0 ko:K02109 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 iHN637.CLJU_RS01170 1.0 ATP-synt_B,DUF2130 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 893598 0 0 0 0 808506 0 0 0 0 1213848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386239 0 0 0 0 505516 0 0 0 0 460792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276588 0 0 0 0 443165 0 0 0 0 386601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 969911 0 0 0 0 1052342 0 0 0 0 1117825 0 0 0 0 0 0 0 0 0 0 -AAAEAIKPMC(Carbamidomethyl)ELQYELAK MGYG000003697_00700 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 208588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 978631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEAIKPMC(Carbamidomethyl)ELQYELAKEK MGYG000003697_00700 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 811916 0 0 180256 0 0 0 0 0 0 0 0 0 507546 0 0 0 0 0 82617 0 327467 0 0 0 0 0 0 0 0 687215 151655 0 0 0 76844 0 0 0 0 0 319093 0 0 0 0 0 0 0 0 0 85625 0 0 0 0 0 0 0 323265 0 0 0 0 0 0 0 0 0 0 0 0 0 375480 0 0 698246 0 0 969439 0 0 0 0 0 0 0 0 0 226443 0 0 0 0 0 980037 0 1115248 0 0 0 0 0 0 0 0 0 897118 0 0 0 928803 0 0 874556 0 0 781388 0 0 0 0 0 0 0 0 0 707272 0 0 0 0 0 930167 0 440540 0 0 0 0 0 0 0 0 589544 918046 0 0 0 551712 0 0 0 0 0 1571598 0 0 0 0 0 0 0 0 0 627696 0 0 0 0 0 899125 0 1424254 0 0 0 0 0 0 0 0 767601 768260 0 0 0 0 -AAAEAK(Lys->Glu)AAEAPK MGYG000004276_00796 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4|s__ER4 sp900550165|m__MGYG000004276 1.0 COG2768@1|root,COG2878@1|root,COG2768@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,2N6NY@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Putative Fe-S cluster 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_13,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 558734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEALAAK MGYG000003921_00586 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,3WH8C@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 T 1.0 domain protein 1.0 yybT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DHH,DHHA1,GGDEF,PAS_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1028288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEALGMPLYK MGYG000004893_01711;MGYG000000953_00361;MGYG000002485_02554 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0148@1|root,COG0148@2|Bacteria,378QW@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 H 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 114883 0 97673 57956 48191 144727 31862 370397 52830 76601 74944 0 61130 0 119500 55550 0 0 74165 0 0 141188 0 0 0 79079 0 0 0 65375 0 0 162855 89364 0 200070 60218 0 0 0 9012607 3173544 8463058 13466596 8470789 6887209 5028220 13774861 10936910 6594848 11350908 0 7271673 13223122 0 0 6278550 0 7407027 13634234 0 0 0 8935479 7965081 0 0 7723113 0 0 11278835 5906288 7960447 7355184 7494476 0 0 0 61524 47309 58540 60103 530277 0 59659 0 49914 88033 293075 0 67378 0 0 0 252621 0 60084 70541 0 202047 0 0 57028 0 0 51840 0 0 69745 0 0 0 0 67238 140639 0 150485 172781 63070 82799 76490 74160 62503 0 0 146124 0 0 76182 0 0 0 52474 0 945588 86378 0 259908 0 98873 211131 0 0 76255 0 0 150420 75494 61930 62306 0 140861 144715 0 0 77035 0 0 237804 55594 163735 146639 0 246117 0 0 191003 27577 0 0 129586 0 0 0 0 0 0 100480 128415 0 0 0 0 0 0 56848 0 0 0 0 -AAAEALGTSLYNYIGGANAK MGYG000000099_02352 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,268GV@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 479534 111334 0 0 0 0 0 0 0 0 0 0 0 89232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1039995 0 0 1346712 0 0 1505931 978377 0 941231 0 0 0 1159028 1247593 0 932148 0 0 1208132 0 0 0 0 0 1030712 1197280 0 1409338 0 0 0 0 1092313 814165 1130837 725452 0 0 0 0 683255 0 0 0 234724 0 106621 0 0 0 285108 351514 0 870132 0 0 0 0 0 0 0 0 0 0 0 599521 0 0 0 0 641762 151049 0 0 0 0 0 0 0 0 0 200968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5783 0 0 0 0 0 0 0 0 0 0 917696 0 0 0 0 0 0 0 0 0 0 2318896 0 0 3117452 0 0 0 0 0 88718 0 94638 0 -AAAEAPAEEAAAAPAEEAPATEAAAE MGYG000001378_01465;MGYG000001345_02599 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 598635 0 0 0 0 424135 1075325 0 0 1008345 2527839 0 0 0 0 0 0 0 0 0 861671 723105 0 1017039 0 776951 867582 0 0 0 0 0 0 0 0 946299 807632 0 245730 0 0 0 0 229532 124684 0 0 247293 1194881 0 0 0 0 0 0 0 0 0 108763 304976 0 335782 0 415106 161256 0 0 0 0 0 0 0 0 131017 358933 0 0 0 0 0 0 219486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525025 0 267999 0 0 0 0 0 0 0 0 0 271034 0 0 425987 0 0 0 0 486902 512241 0 0 218154 1159409 0 0 0 0 0 0 0 0 0 803992 0 0 385367 0 276429 391351 0 0 0 0 0 0 0 0 422449 389029 0 0 0 0 0 0 737021 281100 0 0 333079 123281 0 0 0 0 0 0 0 0 0 0 198369 0 908704 0 140711 0 0 0 0 0 0 0 0 0 270677 215183 0 -AAAEAPAEEAPAEEAPAAEEAAAE MGYG000001346_00042 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1304415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3463504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEAPAEEATEAAAEEAPATEAAAE MGYG000002561_03440 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp902388495|m__MGYG000002561 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEAPAEEATEAPAEEAAATEAAAE MGYG000000196_03725 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 1149947 0 0 1170133 0 1001350 894974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1022278 0 0 0 1083596 0 0 740564 0 0 0 0 0 0 0 0 0 0 337736 0 534084 726664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271815 0 0 0 436967 0 0 385508 0 0 0 0 0 0 0 0 0 0 439442 0 176197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189999 0 0 261757 0 0 0 0 0 0 0 0 0 0 207587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260218 0 0 243884 0 0 0 0 0 0 0 496354 0 0 160776 0 200385 277774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366735 0 0 0 215908 0 0 510646 0 0 0 0 -AAAEAPAEEATEAPAEEAPAAEAAAE MGYG000002455_05203 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1023408 0 0 0 0 751520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEAPAEETAAPAEEAPATEAAAE MGYG000002549_01142 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1238453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 202605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1365303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEAYFGK MGYG000000196_01844;MGYG000000029_02657;MGYG000003312_02145;MGYG000001345_04496 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 3954518 3961676 2324731 4537009 1979347 2905371 4879439 3156055 3697030 3238535 1769904 2947706 1987293 2465771 3039415 2375072 3861903 1180260 2422244 3727546 3942283 1865545 1799105 4061411 3021561 3550310 3789243 0 4912967 3892245 2785494 3848743 2898626 4419537 4801713 4916346 3285577 2596846 3163828 2098386 3219711 3508390 2865862 0 2301861 0 2955972 3182740 3351876 0 2799437 3352210 0 0 2650855 1328287 2624819 2469130 2856382 3907625 1789599 2664303 3112427 0 2543256 1420020 2920719 2771141 2009424 2620327 2443549 2876818 0 2816028 2955962 0 2008721 644779 1588591 1906851 2608211 2209051 2783542 1827651 2415679 1273293 1553952 1234892 1179920 1786716 1846324 1239330 1612443 2636244 1373518 1586878 2065635 1263719 1896808 2621888 1752535 1936752 1611486 818896 1605079 1141266 1698135 1330942 1167874 1546418 1237894 2428417 0 1478959 1032956 1005216 1207197 1201005 993644 964722 1328316 940725 945314 1142607 1478428 1282318 1516712 861619 748985 887238 1209566 1104317 623387 819565 1096251 724694 1472589 609689 1278446 1337484 880707 740764 557287 1097776 893992 1179115 1029409 1123164 1184085 1390570 1041558 775246 2642867 1627891 0 2323010 2036558 3439590 2769274 2868851 2949110 1846696 1336555 1933805 1996540 1623418 1922730 2159375 2141558 1686295 1537736 2806146 2354687 3614838 1674595 3664830 2672422 3283423 2090406 1426841 1647304 3182863 1863645 2248412 1185087 3136323 2491381 2088320 2729601 1690327 -AAAEEAGASGDSAPK MGYG000004158_01106;MGYG000004158_01109;MGYG000001683_02241 domain d__Bacteria 1.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H3G4@909932|Negativicutes 1.0 909932|Negativicutes 1.0 P 1.0 Transporter DASS family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CitMHS,Na_sulph_symp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 1098727 0 963242 1399777 0 0 0 0 0 1760935 0 0 0 0 1124802 0 0 0 1039666 0 0 0 0 1058578 0 0 0 1635137 0 1776682 1390904 0 1280737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEEAGITPETSASDTC(Carbamidomethyl)DKMK MGYG000000233_00306 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,21XVQ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Receptor family ligand binding region 1.0 braC 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 782663 0 0 1096031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEEHHVEYEER MGYG000000028_00251 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus_A|m__MGYG000000028 1.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family 1.0 lysS 1.0 - 1.0 6.1.1.6 1.0 ko:K04567 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03658 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DUF2156,tRNA-synt_2,tRNA-synt_2_TM,tRNA_anti-codon,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine--tRNA ligase. lysyl-tRNA synthetase. - ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 785661 0 151045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEELGLK MGYG000002960_00316;MGYG000002293_01627 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,2FPIS@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Carbohydrate kinase, FGGY family protein 1.0 xylB_2 1.0 - 1.0 2.7.1.17 1.0 ko:K00854 1.0 ko00040,ko01100,map00040,map01100 1.0 M00014 1.0 R01639 1.0 RC00002,RC00538 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 xylulokinase. Xylulose kinase. - ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+). 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7317666 0 0 0 0 4303703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEEVLGKDER MGYG000001346_02345 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0312@1|root,COG0312@2|Bacteria,4NE1F@976|Bacteroidetes,2FPXY@200643|Bacteroidia,4AMRA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Psort location Cytoplasmic, score 9.26 1.0 tldD3 1.0 - 1.0 - 1.0 ko:K03592 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01002 1.0 - 1.0 - 1.0 - 1.0 PmbA_TldD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 323837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEFTDVK MGYG000002720_00025;MGYG000004475_00733 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,2N6G4@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate-binding protein PnrA-like 1.0 tmpC 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 7850631 0 7747171 7463496 0 8415019 9263167 8119035 0 0 0 0 0 0 7288557 0 8206658 0 0 0 0 7375610 0 7939648 7872468 7788271 0 0 10671868 0 6398930 6821235 6843128 0 7760422 0 8366962 7156853 0 0 208628 334285 0 337124 583249 412177 0 0 0 0 0 0 263866 0 330088 0 0 0 0 253522 0 447590 464326 482589 0 0 601020 0 0 101497 178173 0 205540 0 256523 461290 1138777 0 814416 612433 0 839775 576465 1231364 0 0 0 0 0 0 389895 0 581124 0 0 0 0 475825 0 722666 703139 560182 0 0 614153 0 745077 818521 323071 0 174176 0 651445 568808 813090 0 2033564 982436 0 950086 1512362 1226020 0 0 0 0 0 0 988179 0 1455992 0 0 0 0 2380097 0 2025231 974392 844501 0 0 1494371 0 1414053 420400 1558970 0 1042970 0 732704 2186523 653125 0 0 125002 0 0 125309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164345 0 0 0 0 0 200594 335075 140756 0 0 0 0 115406 -AAAEGAGAAEKDEFDVELTSAGASK MGYG000000249_00044 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 921219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEGAIGIAEK MGYG000000118_02684;MGYG000000142_02731;MGYG000000038_01050;MGYG000004604_01207;MGYG000001338_01296;MGYG000000179_04738;MGYG000000127_05084;MGYG000002528_00119;MGYG000000515_00648;MGYG000000205_02543;MGYG000000217_02528;MGYG000002985_01044;MGYG000000262_01832;MGYG000004762_01356;MGYG000002517_01686;MGYG000000187_00466;MGYG000000212_00326;MGYG000002492_01963;MGYG000000198_05683;MGYG000000245_00061;MGYG000000280_02029;MGYG000000251_02115;MGYG000000312_02568;MGYG000001615_01983;MGYG000000233_02118;MGYG000001496_01287;MGYG000000249_02372;MGYG000001707_00757;MGYG000002880_00963;MGYG000003425_04615;MGYG000004733_02764;MGYG000000301_00647 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.375 186801|Clostridia 0.90625 S 0.90625 Psort location Cytoplasmic, score 8.87 0.46875 - 0.90625 - 1.0 - 0.90625 - 0.90625 - 0.90625 - 0.90625 - 0.90625 - 0.90625 - 0.90625 - 1.0 - 1.0 - 1.0 GGGtGRT 0.90625 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.90625 0.90625 0.90625 0.90625 0.90625 none 1.0 1353283 1319401 293497 336510 0 0 0 0 0 677756 0 0 0 0 0 0 0 0 480979 589634 0 0 0 0 616051 0 0 457556 989322 0 349113 0 996222 0 0 582881 0 328173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733947 0 0 0 0 279440 0 0 0 0 1041098 0 0 0 0 0 0 0 0 0 163806 1842006 1359610 2129733 1506395 0 0 1073621 0 0 1780562 0 0 0 1345052 0 1201707 924491 644355 1751896 1758464 0 0 869007 0 1690634 1590410 1472810 823679 1533508 0 574717 1196358 1738905 1944562 0 1392878 1894479 1733136 564584 948226 0 756790 0 0 0 0 0 604488 0 0 0 730160 0 609209 1002843 668523 391503 904978 0 0 344585 0 311406 0 755523 1584174 1226275 0 1046080 365416 566092 0 0 444831 370296 1010447 464782 335254 930728 1438745 0 0 1758943 0 0 1603275 0 0 0 1235243 0 257826 0 552664 1280651 496060 0 0 909443 0 953877 956465 1412484 830785 1702111 0 788173 450428 1238903 391432 0 617843 1019116 804706 -AAAEGAIGIAR MGYG000001627_00963;MGYG000001300_02120;MGYG000002274_00309;MGYG000000258_00155;MGYG000003937_01695;MGYG000000223_01510;MGYG000004732_00759 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae 0.8571428571428571 186801|Clostridia 0.8571428571428571 S 1.0 Psort location Cytoplasmic, score 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 408935 657154 0 0 0 0 0 0 0 1469548 0 0 454506 0 0 0 0 0 0 1102504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432362 0 0 0 0 687091 0 0 0 0 594983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1344608 1296666 0 0 0 0 0 0 0 2044391 0 0 0 0 1583236 0 0 0 952885 0 0 1594459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2349389 0 0 973904 0 2164089 0 0 0 1426979 3361848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEGDGDMINGR MGYG000002293_01819;MGYG000001338_00685;MGYG000003697_01754 domain d__Bacteria 1.0 COG2407@1|root,COG2407@2|Bacteria,4NFGS@976|Bacteroidetes,2FMDZ@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 0.6666666666666666 G 1.0 L-fucose isomerase, C-terminal domain 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 129438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1039846 0 0 711613 567534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769318 0 944248 0 0 0 0 0 0 0 0 435381 0 0 0 0 730098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEGELK MGYG000001712_05136 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Bacillales|f__Bacillaceae_G|g__Bacillus_A|s__Bacillus_A thuringiensis_S|m__MGYG000001712 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus 1.0 91061|Bacilli 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gapA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1045065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1250183 0 901588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEGEMK MGYG000002506_01169 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gapA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1210873 0 0 0 935332 1100234 0 1001052 0 0 193734 0 614600 1144256 0 0 540797 0 0 0 1104918 1169438 0 3210204 0 1014549 0 0 728875 0 0 525009 0 966125 915947 0 772984 0 357966 0 0 0 726065 1839359 0 833920 0 0 629846 0 732061 471714 0 0 626508 0 0 0 484061 1448956 0 2074133 0 266681 0 0 545482 0 0 361497 0 63820 446921 0 522296 0 1249172 0 0 0 489602 1598414 0 767746 0 0 662672 0 661518 621511 0 0 1325917 0 0 0 886422 1241476 0 11875454 0 1631137 0 0 290369 0 0 433009 0 1248912 1657751 0 488842 0 212250 0 0 0 199518 1309500 0 755035 0 0 712264 0 2481695 494862 0 0 202294 0 0 0 2157621 2265370 0 1587791 0 695402 0 0 571634 0 0 700280 0 442206 601747 0 542697 0 120950 0 0 0 0 0 0 0 0 0 0 0 0 150603 0 0 0 0 0 0 0 0 0 156588 0 95244 0 0 100497 0 0 0 0 0 239162 0 0 0 -AAAEGIAYVK MGYG000002528_01658 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,24819@186801|Clostridia,21ZS7@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 1.0 carB2 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 216545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1045001 0 388175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEIAGLNNATGC(Carbamidomethyl)DVR MGYG000003895_00007 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Negativibacillus|s__|m__MGYG000003895 1.0 COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,2499C@186801|Clostridia,21YIA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 I 1.0 Psort location Cytoplasmic, score 8.87 1.0 grdC 1.0 - 1.0 1.21.4.2,1.21.4.3,1.21.4.4 1.0 ko:K21577 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ACP_syn_III,FA_synthesis 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine reductase. | sarcosine reductase. | betaine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. | The reaction is observed only in the direction of sarcosine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.4. | The reaction is observed only in the direction of betaine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.3. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. | [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine. | [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 967094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEIEEFR MGYG000000074_02203 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,2FNZN@200643|Bacteroidia,22U4G@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily 1.0 pheS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.20 1.0 ko:K01889 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Phe_tRNA-synt_N,tRNA-synt_2d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 342256 0 332078 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199764 0 0 0 492891 0 0 0 0 0 0 339153 269985 794937 0 659887 0 0 0 0 438344 0 0 0 0 0 0 0 385949 0 0 834715 525155 0 0 0 0 0 543644 0 0 0 285572 0 0 503078 0 0 0 466297 431856 0 0 559374 0 0 0 0 631883 0 0 0 0 0 0 0 326443 0 0 0 476733 0 0 0 0 0 0 0 0 426324 838285 0 0 587253 0 0 0 353138 454557 424407 0 210063 0 0 0 0 426039 0 0 0 0 0 0 0 367889 0 0 0 809450 0 0 0 0 0 609495 0 0 415697 259909 0 0 0 0 0 0 385078 0 856924 0 449903 0 0 0 0 743548 0 0 0 0 0 0 0 929583 0 0 1343032 1669937 0 0 0 0 0 824995 0 0 627498 1214443 0 0 326642 0 0 0 1016761 920007 -AAAEIILK MGYG000000118_02724;MGYG000000133_02501 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C6IR@1|root,33WXF@2|Bacteria,1VVM0@1239|Firmicutes,24QSU@186801|Clostridia 0.5 186801|Clostridia 1.0 - 0.5 - 0.5 - 1.0 - 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEKAEITPDMSTSEIC(Carbamidomethyl)DALK MGYG000000164_00677 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,3WI31@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 ABC-type branched-chain amino acid transport systems periplasmic component 1.0 braC 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 1.0 none 1.0 1922650 0 0 0 1583969 1828018 1878285 3338370 2472681 2782193 0 0 2139680 1529534 2038441 1464392 1598155 0 1768412 2027851 2132483 2119823 0 1356216 2267711 2788653 2770760 0 0 1270179 0 0 0 3248976 0 0 2208595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAELDGPVYMR MGYG000000080_00459 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Transketolase 1.0 tktB 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5840933 0 0 0 0 0 0 0 0 0 -AAAELGYPVIIR MGYG000002293_01440 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 EF 1.0 Carbamoyl-phosphate synthase (glutamine-hydrolyzing) 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1026159 0 0 0 0 1593502 0 0 0 0 850956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAELVQALK MGYG000000179_00905;MGYG000000198_02625 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,21YF6@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 755729 0 0 0 0 0 654759 0 569192 3677255 0 0 0 802494 919173 0 0 0 0 664756 0 0 0 0 0 2973783 139419 0 677771 489946 0 0 0 599035 0 719242 2925299 0 1026528 0 0 0 0 0 170338 0 306593 284543 0 0 0 108072 385021 0 0 0 0 380845 0 0 0 0 0 372015 345924 0 1268509 142538 0 0 0 179634 0 1361947 272180 0 2908453 0 0 0 0 0 3240502 0 1037178 3864546 0 0 0 1012063 923673 0 0 0 0 3433104 0 0 0 0 0 721151 961680 0 1164791 4656412 0 0 0 3666199 0 3406790 696036 0 627562 0 0 0 0 0 2703870 0 3710333 0 0 0 0 4344966 4605026 0 0 0 0 0 0 0 0 0 0 569139 762129 0 745574 4082023 0 0 0 585123 0 715755 564121 0 1069050 0 0 0 0 0 787472 0 2711595 699576 0 0 0 897225 994518 0 0 0 0 1416306 0 0 0 0 0 799129 1053180 0 923955 982708 0 0 0 1250829 0 842912 662658 0 -AAAENIIPHTTGAAK MGYG000002506_00654;MGYG000002494_01095;MGYG000002515_01523;MGYG000002534_02628;MGYG000002477_03045 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,3XQM0@561|Escherichia 0.6 1236|Gammaproteobacteria 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.6 gapC 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iJR904.b1416,iJR904.b1417 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 379906 808312 0 0 0 224356 0 0 0 480634 0 0 0 0 0 0 0 0 182916 0 0 119187 0 238780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 720127 1945041 1559459 0 0 3058883 0 0 0 805746 0 0 0 0 0 645323 1260716 0 1183847 0 0 3041346 0 2740798 784535 480611 0 0 2095126 0 0 0 1586799 0 0 637802 529284 1438200 0 164118 452385 0 0 0 0 0 0 0 0 0 0 0 0 0 300242 0 276204 0 0 388786 0 300145 0 0 0 0 0 0 0 0 236095 0 0 0 267570 358643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99080 556286 450620 0 0 589156 0 0 0 444573 0 0 0 0 0 716509 522133 0 288717 0 0 668679 0 587728 460009 716831 0 0 483980 0 0 0 0 0 0 0 83700 0 -AAAENMIPTSTGAAK MGYG000001712_05136 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Bacillales|f__Bacillaceae_G|g__Bacillus_A|s__Bacillus_A thuringiensis_S|m__MGYG000001712 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus 1.0 91061|Bacilli 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gapA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 240317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907188 0 496300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEPAPVNPC(Carbamidomethyl)IR MGYG000002272_02058 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_D|m__MGYG000002272 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4,Fer4_10,Fer4_4,Fer4_7,Fer4_8,Fer4_9,MTHFR_C,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 643031 0 0 0 0 661950 0 0 0 0 688463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293811 0 0 0 0 0 0 0 0 0 598469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 500944 0 0 0 0 614372 0 0 0 0 648142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 835756 0 0 0 0 667393 0 0 0 0 1166904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEQDYEEFGKK MGYG000000243_00376 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,4AK9W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrA 1.0 - 1.0 1.6.5.8 1.0 ko:K00346 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQRA,NQRA_SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1605878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 917046 0 1315366 0 0 0 0 1414751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEQELTR MGYG000001300_02745 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 P 1.0 Belongs to the TelA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TelA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 878235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 795650 0 0 0 0 0 519205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEQELTRIEDELK MGYG000001300_02745;MGYG000002223_00590 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 P 1.0 Belongs to the TelA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TelA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 349142 0 0 0 230442 0 0 0 0 204137 156886 0 0 501075 53785 0 604709 132327 0 0 0 0 181223 192314 0 0 0 290889 80604 0 212464 108888 0 0 208393 114078 393593 0 320480 0 352213 0 601063 0 0 0 0 435131 467138 0 0 340607 537950 0 703598 503470 0 0 0 0 654407 723472 0 0 0 294403 392718 0 431262 353973 0 0 415439 345026 180296 0 491970 0 556434 0 560436 0 0 0 0 268821 210337 0 0 383592 148364 0 409166 238420 0 0 0 0 211493 72185 0 0 0 209189 318450 0 144768 158071 0 0 156447 143717 361738 0 463300 0 509611 0 246453 0 0 0 0 468574 496771 0 0 474152 219792 0 462898 328712 0 0 0 0 200543 432806 0 0 0 432694 498919 0 699694 474070 0 0 362546 542461 109894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316222 47466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAESFADFAK MGYG000002279_02340 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena_B|m__MGYG000002279 1.0 COG1653@1|root,COG1653@2|Bacteria,1TPBF@1239|Firmicutes,24920@186801|Clostridia,27UWQ@189330|Dorea 1.0 186801|Clostridia 1.0 G 1.0 COG COG1653 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAESSIQVK MGYG000002477_00984;MGYG000002494_02482;MGYG000002500_00413;MGYG000002507_00338;MGYG000002506_03694;MGYG000002534_04617;MGYG000002476_04022;MGYG000002535_04027;MGYG000002515_03649 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0085@1|root,COG0222@1|root,KOG0214@2759|Eukaryota,KOG1715@2759|Eukaryota,39VWS@33154|Opisthokonta,3BM6Z@33208|Metazoa,3DDNE@33213|Bilateria 1.0 33208|Metazoa 1.0 K 1.0 DNA-directed 5'-3' RNA polymerase activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7,Ribosomal_L10,Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 593106 573026 450901 131447 209194 1006712 941615 918145 604044 852311 0 543815 0 723950 411779 229891 157286 0 358692 320009 429541 1422526 0 1477902 504158 506666 353979 0 389519 536299 604876 640270 513932 752009 487272 248082 0 497685 3394296 3633691 3657801 2648138 2668782 5278678 2975432 2783765 3860489 3927483 0 2410145 0 2946491 2633772 1949391 3766746 0 3761749 2238469 4283122 6168366 0 4356663 3136178 2716305 2528639 0 4766958 4247465 1575272 2461919 4194334 2786619 2532971 2371080 2677098 2849692 952478 1167296 1179615 985534 1217163 2336601 1558371 929899 174976 1386584 0 538438 0 1517043 978234 982332 1029455 0 867910 788161 1224008 1924233 0 2069402 811327 1076926 991320 0 1010462 1272072 1473771 740320 1208591 1310051 1055671 0 1158923 591302 218591 0 0 268584 755483 837492 2200390 730941 0 429737 0 0 0 687074 1446171 175760 1441782 0 0 1063365 1510818 1439997 0 0 301461 0 0 0 213300 220692 0 0 0 2019930 1887759 1769259 901545 741981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285433 0 0 0 -AAAESYLGK MGYG000001661_01238;MGYG000001337_04131;MGYG000000243_03128;MGYG000001313_00261;MGYG000000236_03748;MGYG000000224_00588 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 312702 0 0 0 0 344660 0 0 0 0 0 0 0 0 0 0 0 310765 0 0 138222 230367 0 225472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192943 0 0 0 0 0 130512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3293055 0 0 0 0 3289070 4557739 0 0 0 0 0 0 0 0 0 0 18183206 0 0 3155456 2542865 14550410 791479 0 2344002 0 12682528 0 0 0 0 0 0 0 0 2877768 0 784153 0 0 0 0 1312662 1091733 0 0 0 0 0 0 0 0 0 0 2943821 0 0 284944 1370474 1320577 1547659 0 859685 0 1851794 0 0 0 0 0 0 0 0 470706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 922532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAETYFGK MGYG000002549_03156 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 92682 0 0 0 136220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196480 0 0 0 0 0 0 0 0 0 0 0 0 0 1320579 0 0 0 3377779 0 0 0 2173885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 774066 0 0 0 1710109 0 0 0 0 0 0 0 0 0 610318 0 0 0 1378697 0 0 0 502839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 620985 0 0 0 327356 0 0 0 0 0 0 0 0 0 516313 0 0 0 683545 0 0 0 661980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511717 0 0 0 724279 0 0 0 0 0 0 0 0 0 1066958 0 0 0 2094794 0 0 0 914263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055276 0 0 0 1309084 0 0 0 -AAAETYGIK MGYG000000445_01242 genome d__Bacteria|p__Proteobacteria|c__Alphaproteobacteria|o__RF32|f__CAG-239|g__RUG410|s__|m__MGYG000000445 1.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2TQM1@28211|Alphaproteobacteria,2JUHP@204441|Rhodospirillales 1.0 204441|Rhodospirillales 1.0 GM 1.0 Oxidoreductase family, NAD-binding Rossmann fold 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GFO_IDH_MocA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 933678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAETYL(Xle->Phe)GK MGYG000003681_02191;MGYG000004763_02569;MGYG000004797_03123;MGYG000002478_01519 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1294522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1438717 0 0 0 0 0 0 0 0 -AAAETYLGK MGYG000003681_02191;MGYG000004763_02569;MGYG000004797_03123;MGYG000002478_01519 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 281497 611568 342825 653181 0 419012 505095 362176 495582 691456 299852 289076 0 285727 294347 364472 770369 596194 483326 0 416771 489405 360414 580058 0 573344 546485 321114 172771 518982 227432 685508 577118 0 658330 503338 544413 372458 4074378 1950228 3143243 4704635 0 2477579 3427650 4447976 4862117 4402100 2025344 4592110 0 4659902 3609173 2252263 3088394 2714717 3707664 4272453 3478299 2763107 4122837 2610476 0 4154355 3989189 3760805 3105810 4398860 2039575 2448023 3097965 0 5115604 2267278 5152768 4378134 1034585 442745 916717 725146 0 868375 1366429 696875 1335297 775116 925394 558086 0 1280196 1208287 418418 994688 4739840 990725 829333 939181 524443 3545422 1182345 0 975048 942695 3443481 988600 881378 849024 705911 405463 0 687659 1244367 1044905 768252 319627 910648 743995 273653 0 857898 1020957 0 429064 531019 1163614 820583 0 0 505621 1146553 0 2559887 1034205 0 0 1049307 1699597 610555 0 918841 248117 1345404 853626 393964 814031 862963 645656 0 411087 994301 570730 739683 119675 0 0 224599 0 0 0 0 0 0 0 0 0 0 0 0 0 1885771 0 0 0 0 1218952 0 0 0 0 806900 0 0 0 107336 404894 0 266708 0 561241 0 -AAAETYLSK MGYG000002455_01371 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEVAGLLNATGSDSR MGYG000001315_00855 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,2499C@186801|Clostridia,27JWX@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 I 1.0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 1.0 grdC 1.0 - 1.0 1.21.4.2,1.21.4.3,1.21.4.4 1.0 ko:K21577 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ACP_syn_III,FA_synthesis 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine reductase. | sarcosine reductase. | betaine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. | The reaction is observed only in the direction of sarcosine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.4. | The reaction is observed only in the direction of betaine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.3. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. | [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine. | [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate. 1.0 1.0 1.0 1.0 1.0 none 1.0 681382 788498 1189194 536787 1245255 746712 385707 548375 636131 935656 1447062 935133 885598 613966 834148 891334 702814 430797 824057 664228 0 722658 338068 513973 593004 496870 509514 197755 502289 428923 58669 664317 879938 529328 538151 690790 297327 934870 2555302 2300597 1264319 2682995 1517429 1473126 2649665 2720792 1674828 1411283 1201293 1506788 1777402 1713479 1664436 1022281 1499818 1637220 2315446 2574512 0 808144 299943 2335080 2345688 2347449 2722844 1151422 3088183 1671778 3012073 1842531 1439911 2689570 2106388 3007057 2042739 1312159 897378 821415 937578 789004 581621 116802 646921 957022 935038 751616 728866 821354 915112 742884 972361 786433 1014158 880776 645311 881085 0 1078695 806787 636540 882015 891712 1015813 1233067 255164 845351 626377 0 846728 1198426 903918 603685 711622 535644 894260 1051763 974641 529692 947405 718868 717402 658881 498072 690612 695534 945699 1123941 737848 812218 1256474 823312 574647 808947 1082763 0 1110543 153927 804022 779334 713581 888272 549971 0 902823 868504 1220320 987062 494045 710997 610912 589139 998732 0 890467 1635478 2570603 631394 1070255 2273519 1866181 1356371 1930034 1763556 1428595 937540 2650166 1449723 1450169 1510183 539731 1184604 941101 0 1647875 252788 1315449 2047773 1276745 1832111 610105 2350498 582221 1835891 0 528311 0 2057875 2409237 1308889 1586661 -AAAEVAGLVSA(Ala->Gly)TGSDAR MGYG000001496_02720 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Extibacter|s__Extibacter sp001185345|m__MGYG000001496 1.0 COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,2499C@186801|Clostridia,21YIA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 I 1.0 Psort location Cytoplasmic, score 8.87 1.0 grdC 1.0 - 1.0 1.21.4.2,1.21.4.3,1.21.4.4 1.0 ko:K21577 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ACP_syn_III,FA_synthesis 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine reductase. | sarcosine reductase. | betaine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. | The reaction is observed only in the direction of sarcosine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.4. | The reaction is observed only in the direction of betaine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.3. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. | [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine. | [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEVAGLVSAT(Thr->Ser)GSDAR MGYG000001496_02720 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Extibacter|s__Extibacter sp001185345|m__MGYG000001496 1.0 COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,2499C@186801|Clostridia,21YIA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 I 1.0 Psort location Cytoplasmic, score 8.87 1.0 grdC 1.0 - 1.0 1.21.4.2,1.21.4.3,1.21.4.4 1.0 ko:K21577 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ACP_syn_III,FA_synthesis 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine reductase. | sarcosine reductase. | betaine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. | The reaction is observed only in the direction of sarcosine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.4. | The reaction is observed only in the direction of betaine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.3. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. | [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine. | [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate. 1.0 1.0 1.0 1.0 1.0 none 1.0 125411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 506600 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1011961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1167909 0 0 0 0 0 0 0 0 0 0 1047627 0 472218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEVALK MGYG000001338_00592 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3Y0DB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4253125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3826014 0 0 0 0 0 0 1266647 0 2763584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5488512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3047295 0 1403156 0 0 0 0 1672651 0 738427 764514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1502672 0 1728788 0 0 0 0 1360571 -AAAEVALKDAVSTISK MGYG000000200_02066;MGYG000001338_00592 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3Y0DB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 798085 181566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246349 454663 168258 0 0 0 0 153505 0 853373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1008428 212237 0 0 0 0 0 0 0 1464891 187356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284681 1132867 433658 0 0 0 0 218876 0 341207 158452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293114 450217 167770 0 0 0 0 0 0 1280689 731570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146282 1006582 853909 0 0 0 0 514951 -AAAEVATEVVDAVK MGYG000003937_00337 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG3940@1|root,COG3940@2|Bacteria,1UK7P@1239|Firmicutes,25FPI@186801|Clostridia,3WSNK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Ricin-type beta-trefoil lectin domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 RicinB_lectin_2 1.0 - 1.0 CBM13 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 862845 0 0 915701 0 0 0 0 0 925936 0 1070965 0 1086321 1058090 0 1287329 0 785430 0 0 913032 0 925713 0 0 1139950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405334 0 0 203754 0 0 0 0 0 668662 0 207065 0 283906 562777 0 634363 0 150588 0 0 210603 0 278782 0 0 566769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264231 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAEYAATR MGYG000002961_01578;MGYG000001642_01246;MGYG000001709_01740;MGYG000001567_00451;MGYG000003266_01787;MGYG000002919_01660;MGYG000002947_01105;MGYG000002775_01057;MGYG000004681_01444;MGYG000001718_00699;MGYG000000188_00729 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4CUV7@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 F 1.0 SAICAR synthetase 1.0 purC 1.0 - 1.0 6.3.2.6 1.0 ko:K01923 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04591 1.0 RC00064,RC00162 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 SAICAR_synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase. SAICAR synthetase. Forms part of the purine biosynthesis pathway. 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate + ADP + 2 H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 1513157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAFEGELIPASQIDR MGYG000002535_04030;MGYG000002506_03691;MGYG000002323_03991;MGYG000000107_05463;MGYG000003365.1_02175;MGYG000003390_01039;MGYG000000235_04432;MGYG000002494_02479;MGYG000002366_04477;MGYG000002500_00410;MGYG000003360_03951;MGYG000002534_04620;MGYG000002515_03652;MGYG000000093_05651;MGYG000002502_01841;MGYG000002507_00341 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,3XM5M@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 2613041 2053670 2198962 3127702 1810110 3271554 3529737 2867816 3084954 3635005 1259724 2450092 957403 2365675 2109836 1156676 2723403 0 2381003 2530192 2620049 4045255 0 4542883 2488505 2342675 2958363 0 3307614 3022307 2170861 2367379 1913861 3339442 2471574 2897143 2517908 1938569 4646632 4617078 5060882 7139531 4893065 11662186 6212529 5275563 5401268 7967050 2057283 4874771 2912801 6376898 6260363 3418801 5454204 0 7388183 5067807 7255465 13684547 0 11132172 6808654 6189355 5738044 0 9108984 7747551 3671099 4349434 5694404 4755471 5121562 4954322 5070780 4274285 3389114 2171316 3630448 3179553 2958916 6571765 4319563 3850201 3398622 4570797 2673286 3064124 3196173 3313767 3417679 2384221 1812981 0 3208558 3846796 2831742 4619709 0 5162732 4043332 3551410 3807204 0 2180048 2765241 2973046 2013088 3052349 4416145 3776150 3777641 4012905 3247349 4096201 2651872 2859237 3262969 2343902 3829437 4042594 4456950 2704836 4054313 1919370 3050486 3084852 3462893 3782112 2940156 2946071 0 3375442 3314526 4179781 4004617 0 3151616 4761285 3509939 3960388 0 3118434 3342510 1541765 3054153 3496027 4682428 4851796 4201719 3076376 2383166 0 0 0 0 0 0 0 0 0 0 0 760380 0 411739 0 0 0 0 0 0 780636 0 0 0 435734 0 0 0 198269 276609 0 0 652514 0 0 0 0 0 -AAAFIGKDEEA MGYG000001306_01210 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,4AN49@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1872657 0 0 0 0 2164460 0 0 0 0 1994383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293107 0 0 0 0 320196 0 0 0 0 216177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 601886 0 0 0 0 22629843 0 0 0 0 18502418 0 0 0 0 0 0 0 0 0 0 -AAAFIKEDEEA MGYG000000196_04090;MGYG000000236_02874;MGYG000001313_02980 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,4AN49@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2454451 1844730 0 2466465 0 0 0 0 0 0 1298951 0 0 0 0 0 0 0 0 0 0 0 0 1368913 0 0 0 0 0 0 0 0 0 0 1531588 0 0 0 1427785 1815505 0 0 0 0 0 0 0 0 1211920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1360806 0 0 0 0 0 0 0 0 0 0 0 0 516464 0 153890 0 0 0 0 0 0 703629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 730023 0 0 0 1471403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1538614 0 0 1318291 0 0 0 0 0 0 0 485044 0 0 0 660402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAFLKEDEEA MGYG000002478_01738;MGYG000003312_00466;MGYG000002281_00010;MGYG000004797_01414;MGYG000001378_03198;MGYG000000196_04090;MGYG000002455_03780;MGYG000000236_02874;MGYG000001313_02980 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,4AN49@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1577973 1524689 1491075 2061635 1363743 1574025 2915848 1188624 2988337 1866548 1605181 1206663 3120900 2075168 1328246 2703415 2559685 1852337 2797782 1553513 1667740 1172144 986846 1725723 1989815 2527045 1211597 1840372 2301790 1534038 1862195 1425509 1219867 1247279 1288117 2580620 1174284 930410 1951247 890909 1971395 1568601 1993458 0 1690616 1984184 1966598 2587971 2345135 1645366 2894046 2793021 2680479 3052833 1181077 945004 1639468 1964936 0 1801056 1244005 1238801 2154106 2198852 1388609 1104998 1902597 1907971 0 1595727 1587859 1814006 2154267 1471161 2191007 1514922 1446640 729750 681113 992872 1396238 1239516 1719037 1011067 922691 972111 1177941 879648 0 740279 1123590 988598 1111815 2473318 1082929 1044458 710494 925992 2118418 1712792 885378 654032 1117465 1864246 1322961 801815 1233610 945206 489913 1086190 640905 1692632 1014033 879755 832798 802429 1010601 692983 1037380 1137978 881084 622662 713667 867652 1291009 857472 1526984 692720 729599 1669403 477188 1470158 646320 737452 888064 1302764 2406827 1168898 875572 1026139 580812 1395865 1096235 1262964 1169476 995836 1349172 524810 1121054 1085832 764841 396458 1440894 640706 1509172 2005152 3082691 1797541 2535125 1976195 2293564 1633590 3162186 1798492 2932075 1238435 1797041 1783653 2191941 4850372 2593618 1878196 2027286 1533027 3793793 1446464 1927136 1683496 1438463 3441423 1465545 3123700 1636372 1953714 434048 2346349 1976510 1724909 914003 2028615 -AAAFMKDEEEA MGYG000000243_02464 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,4AN49@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 1212480 1981353 0 1244317 0 0 2707236 0 1276223 1401155 1478053 0 0 1880047 0 0 868519 0 0 0 0 1345858 0 0 0 0 1099773 0 0 0 0 2709456 2645459 0 0 0 2262251 0 0 0 0 161721 0 0 273081 0 189217 0 0 0 0 201523 0 0 0 0 0 0 0 0 0 0 0 0 112491 0 0 0 0 0 0 0 0 0 0 0 331545 599859 0 833175 0 0 521580 0 379907 0 0 0 0 0 0 0 1762007 0 0 0 0 1325191 0 0 0 0 1289188 0 0 0 0 257842 0 0 0 0 384359 0 217469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 482200 0 0 0 0 0 0 347309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAFMKEEEA MGYG000001780_01720;MGYG000001346_00648 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,4AN49@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1613534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 776009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3188305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1063960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4054954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAFVK MGYG000000133_01636;MGYG000000179_02852;MGYG000004087_00727;MGYG000002720_00599;MGYG000001315_02441 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3XZR6@572511|Blautia 0.2 186801|Clostridia 1.0 I 0.4 Acetyl-CoA carboxylase alpha subunit 0.2 - 0.6 - 1.0 - 0.6 - 0.6 - 0.6 - 0.6 - 0.6 - 0.6 - 0.6 - 1.0 - 1.0 - 1.0 Carboxyl_trans 0.4 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.6 0.6 0.6 0.6 0.6 none 1.0 0 0 143233 113433 0 0 0 0 0 0 0 0 0 57659 0 0 0 0 0 0 255594 0 0 0 0 0 49296 0 59190 0 0 0 237949 147978 0 0 0 473662 0 0 462481 85897 0 0 0 0 0 0 0 0 0 125981 0 0 0 0 0 0 173108 0 0 0 0 0 375178 0 437924 0 0 0 411095 404176 0 0 0 383466 0 0 224786 0 0 0 0 0 0 0 0 0 0 241603 0 0 0 0 0 0 41245 0 0 0 0 0 209737 0 94333 0 0 0 66808 105253 0 0 0 195298 0 0 283338 175487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325054 0 0 0 0 304348 0 0 675458 685297 0 0 0 0 0 0 0 0 0 1174139 0 0 0 0 0 0 466364 0 0 0 0 0 639309 0 845728 0 0 0 999379 729379 0 0 0 678532 -AAAGAAGAVAVK MGYG000001300_00242;MGYG000003166_01306 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 443642 0 240592 606109 0 256750 514399 343302 470325 0 0 236984 152432 407409 0 233013 161172 0 750275 649024 0 267120 0 401523 325738 396870 0 0 0 286466 0 0 345105 0 0 0 356836 207703 5953683 0 5754426 5292035 0 4038380 5419772 2993763 4327985 0 0 4660063 3602626 5211233 0 3140115 6108130 0 5736844 4397347 0 2529299 0 3212633 6623875 5039173 0 0 0 3254175 0 0 5023956 0 0 0 5702754 4342954 538363 0 376455 960401 0 312885 931005 0 577942 0 0 381088 586131 549481 0 506240 361392 0 329011 577901 0 0 0 413235 297975 418394 0 0 0 407687 0 0 254485 0 0 0 501401 422768 2170248 0 3307321 1813316 0 2784574 3413583 1579440 2278129 0 0 3542249 2641215 1543098 0 1850765 2244330 0 2355011 1817517 0 2297621 0 2329467 2165959 2177602 0 0 0 2354117 0 0 2954134 0 0 0 2434501 2395270 954280 0 896757 792324 0 117721 415310 1047698 1025392 0 0 0 0 699024 0 0 1063368 0 685949 845079 0 833931 0 179839 815161 904889 0 0 0 0 0 0 255657 0 0 0 1124018 992714 -AAAGAATEVDLK MGYG000001300_00298 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,3WGGE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acetyl-CoA hydrolase/transferase C-terminal domain 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 2854738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4778309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342865 0 0 0 0 0 -AAAGAGEAAEEKDEFDVELTEVGPNKVK MGYG000000002_03606 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A faecis|m__MGYG000000002 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,27N7Q@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 806211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520989 0 557044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 323282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGAGQNFSLGK MGYG000001313_01386 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,2FKYY@200643|Bacteroidia,4AN2X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarboxypepD_reg,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 375671 0 0 0 0 0 0 0 2245603 0 0 0 0 348218 0 0 0 0 1218108 0 0 883426 0 0 0 0 304369 0 0 0 0 0 0 0 0 0 0 0 2144667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2157087 0 0 0 0 0 0 0 0 0 0 855202 1410218 0 0 0 0 0 0 0 1734508 0 0 0 0 1285676 0 0 0 0 0 0 0 1076067 0 0 0 0 1100859 0 0 0 0 0 0 0 0 0 0 986264 1625634 0 0 0 0 0 0 0 573299 0 0 0 0 0 0 0 0 0 18535557 0 0 1913907 0 0 0 0 805009 0 0 0 0 0 0 0 0 0 0 0 502535 0 0 0 0 0 0 0 0 0 0 0 0 695209 0 0 0 0 0 0 0 0 0 0 0 0 245244 0 0 -AAAGAGSIQVK MGYG000000249_01881 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4741611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGDQLQEWANR MGYG000002517_01937 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia 1.0 186801|Clostridia 1.0 U 1.0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) 1.0 ftsY 1.0 - 1.0 - 1.0 ko:K03110 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SRP54,SRP54_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 487943 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGEAAAAEK MGYG000001302.1_00066 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1433577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1559490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4006368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGEIIVIDSIK MGYG000004487_01021 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900547745|m__MGYG000004487 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,2N6EK@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein L4/L1 family 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 422117 303372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762985 0 0 551706 0 0 0 0 0 0 0 316224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383828 320981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318179 0 0 406474 0 0 0 0 0 0 0 380389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGEIIVVDSIK MGYG000002926_00535 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,2N6EK@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein L4/L1 family 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 709875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300792 0 0 0 0 0 0 0 0 0 0 529433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437854 0 0 0 0 0 0 0 0 0 0 0 0 968805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 651565 0 0 0 0 0 0 0 0 0 0 621530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGEQLSQWADR MGYG000000133_01477 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3XZT9@572511|Blautia 1.0 186801|Clostridia 1.0 U 1.0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) 1.0 ftsY 1.0 - 1.0 - 1.0 ko:K03110 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SRP54,SRP54_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1160016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGEQLTEWANR MGYG000001338_01473 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3XZT9@572511|Blautia 1.0 186801|Clostridia 1.0 U 1.0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) 1.0 ftsY 1.0 - 1.0 - 1.0 ko:K03110 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SRP54,SRP54_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 263053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 555973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGGFQYR MGYG000001757_00012 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Ruminococcus|s__Ruminococcus sp900540005|m__MGYG000001757 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3722314 0 0 0 0 2731287 0 0 0 0 3848436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 549006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGILEQQIH MGYG000000171_00267 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 - 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2628505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGILEQQLH MGYG000000212_00751 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 - 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 963241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2664424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2086270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGISETLLR MGYG000002494_01913 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,3XNGS@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia 1.0 metB 1.0 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.5.1.48 1.0 ko:K01739 1.0 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 1.0 M00017 1.0 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 1.0 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iAF1260.b3939,iBWG_1329.BWG_3608,iECDH10B_1368.ECDH10B_4128,iECDH1ME8569_1439.ECDH1ME8569_3808,iETEC_1333.ETEC_4208,iEcDH1_1363.EcDH1_4046,iEcHS_1320.EcHS_A4172,iEcolC_1368.EcolC_4076,iJO1366.b3939,iJR904.b3939,iUMNK88_1353.UMNK88_4777,iUTI89_1310.UTI89_C4524,iY75_1357.Y75_RS17365 1.0 Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 cystathionine gamma-synthase. O-succinyl-L-homoserine succinate-lyase (adding cysteine). Also reacts with H2S and methanethiol as replacing agents, producing homocysteine and methionine, respectively.-!-In the absence of thiol, can also catalyze beta,gamma-elimination to form 2-oxobutanoate, succinate and ammonia.-!-Formerly EC 4.2.99.9. L-cysteine + O-succinyl-L-homoserine = H(+) + L,L-cystathionine + succinate. 1.0 1.0 1.0 1.0 Sulfur metabolism;Metabolic pathways;Cysteine and methionine metabolism;Biosynthesis of secondary metabolites;Selenocompound metabolism;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1349685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1595557 0 1592374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 404700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471009 0 1058640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGN(Deamidated)IIPSSTGAAK MGYG000004822_01148;MGYG000004757_00364;MGYG000002006_01638;MGYG000001661_02632;MGYG000001749_01249;MGYG000000254_01186;MGYG000004734_01400;MGYG000003697_01698;MGYG000004760_00889;MGYG000004487_00117;MGYG000000086_02423;MGYG000000390_01195;MGYG000002293_01263;MGYG000001608_00559;MGYG000004779_01244;MGYG000004638_00838;MGYG000000377_02142;MGYG000002067_00330;MGYG000003155_00741;MGYG000002834_00628;MGYG000003681_00790;MGYG000002944_01470 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.22727272727272727 976|Bacteroidetes 0.5 G 0.6363636363636364 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8181818181818182 gap 0.9090909090909091 - 0.9090909090909091 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9090909090909091 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGNADDIRPC(Carbamidomethyl)IGC(Carbamidomethyl)LR MGYG000004681_00166 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__|m__MGYG000004681 1.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CU83@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 NADH flavin oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Oxidored_FMN,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGNIIPSST MGYG000002293_01263;MGYG000004734_01400;MGYG000003697_01698 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 0.6666666666666666 G 0.6666666666666666 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 685412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2694764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAGNIIPSSTGAAK MGYG000004822_01148;MGYG000004757_00364;MGYG000002006_01638;MGYG000001661_02632;MGYG000001749_01249;MGYG000000254_01186;MGYG000004734_01400;MGYG000003697_01698;MGYG000004760_00889;MGYG000004487_00117;MGYG000000086_02423;MGYG000000390_01195;MGYG000002293_01263;MGYG000001608_00559;MGYG000004779_01244;MGYG000004638_00838;MGYG000000377_02142;MGYG000002067_00330;MGYG000003155_00741;MGYG000002834_00628;MGYG000003681_00790;MGYG000002944_01470 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.22727272727272727 976|Bacteroidetes 0.5 G 0.6363636363636364 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8181818181818182 gap 0.9090909090909091 - 0.9090909090909091 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9090909090909091 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1208302 1398580 996376 1438592 1284590 1232802 1244629 1350206 1104610 1168589 965318 1125453 1179756 1120189 1186032 0 1162544 989529 1303395 1663503 1491806 896306 1004488 1290257 1372153 1201705 1400235 1124197 1389158 1023299 980068 1389404 1136859 1139238 1395473 1346093 1262886 1031820 8960311 3895674 7222117 7884147 6451408 0 6311214 9213933 9831713 10658312 0 7480150 6152304 9880014 8381763 5932909 6787441 7856578 7592301 8215187 7808634 7246072 0 5123885 7883816 8572780 9018457 8637970 6267733 9158596 4447209 6609318 5974218 8551197 9984561 8696435 9873733 7996450 2511252 2826472 2947643 2959899 3559052 0 3101771 2411292 2601581 2245894 0 2685859 0 2628925 2026926 3170334 3054373 7230293 2529195 2671237 2489822 0 5743961 3226962 2334692 2482048 2518250 4965015 2871380 2434263 3685277 3934920 2692904 2269463 2102741 3151141 2503727 2792950 16226527 9746170 32844169 10088558 16867352 33456789 15120703 22387073 13701130 9167241 24087727 19642096 19393677 12327934 16289960 14627876 9514163 17281592 8129363 8588104 11851068 34810225 28411705 15853263 19877043 20159078 14348778 1592312 7349969 8016819 10137842 18784762 32635755 35001557 18896936 20205838 19455801 20876257 1286216 850094 1010183 1583271 1319110 1343268 1640217 2229223 1515785 1610595 819439 1004340 1662542 1076722 1287085 1581702 0 3814648 1313051 1679643 1187467 970086 2793102 1044121 1799986 1301449 1249695 2536966 1502435 1742825 1346193 1170555 952073 2088636 1862911 1331943 1493486 1115027 -AAAGVILITTK MGYG000001562_01245;MGYG000004876_01631;MGYG000000825_00527;MGYG000002717_02046;MGYG000002478_00534;MGYG000003701_02597;MGYG000001562_02036;MGYG000001789_02639;MGYG000000054_02947;MGYG000002007_00083 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.4 976|Bacteroidetes 1.0 P 0.9 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 388416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318887 0 637366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656169 0 933368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAHEIMDTVLAGDAYK MGYG000001658_01423 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01|s__SFFH01 sp900548125|m__MGYG000001658 1.0 COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1UJBN@1239|Firmicutes,24QYH@186801|Clostridia,26C5N@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,FAD_binding_2,FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1157864 0 0 0 0 2966361 0 0 0 0 639093 835185 0 0 0 0 0 0 0 0 0 -AAAHMVDEVRR MGYG000001661_00238 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides gallinarum|m__MGYG000001661 1.0 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,4AKW4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane 1.0 hppA 1.0 - 1.0 3.6.1.1 1.0 ko:K15987 1.0 ko00190,map00190 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 3.A.10.1 1.0 - 1.0 - 1.0 H_PPase,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 inorganic diphosphatase. pyrophosphate phosphohydrolase. Specificity varies with the source and with the activating metal ion.-!-The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9. cf. EC 7.1.3.1. diphosphate + H2O = H(+) + 2 phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 85023 0 142730 0 0 0 0 0 0 58676 0 0 0 0 0 0 0 0 0 0 580176 0 613070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347937 0 439364 0 0 0 0 0 0 494092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138764 0 0 0 0 0 0 0 -AAAIALDIPLYR MGYG000002517_02082 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 339236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133524 0 0 0 0 385331 0 0 0 0 117237 0 0 0 0 323683 0 0 0 0 247422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 674006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283704 2700551 0 0 0 493296 0 0 0 0 502733 0 0 0 0 630082 0 0 0 0 294399 -AAAIC(Carbamidomethyl)AER MGYG000002506_01784;MGYG000002494_03864;MGYG000002534_03414 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,1RMJS@1236|Gammaproteobacteria 0.6666666666666666 1236|Gammaproteobacteria 1.0 C 0.6666666666666666 belongs to the CobB CobQ family 1.0 pta 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006091,GO:0006113,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008959,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015980,GO:0016053,GO:0016054,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017000,GO:0017001,GO:0017144,GO:0018130,GO:0019413,GO:0019427,GO:0019438,GO:0019541,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046394,GO:0046395,GO:0046459,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070689,GO:0071616,GO:0071704,GO:0072329,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.0 2.3.1.8 1.0 ko:K13788 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iG2583_1286.G2583_2834,iYL1228.KPN_02688 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 1036383 1071481 0 1202497 1305528 1620279 0 0 1228769 0 0 2081650 1207197 1044656 1359136 982636 0 1329548 689586 1137720 1532765 0 2284194 1263976 0 0 0 1552100 0 0 1430021 1184085 0 0 0 0 1179076 0 2634145 1623492 0 2043697 4261583 2209478 0 0 2796316 0 0 1780545 2703372 1481410 2052795 3003217 0 2543133 1588760 2777190 5588779 0 4085878 2279654 0 0 0 3100616 0 0 1835738 2542364 0 0 0 0 1836587 0 895501 964161 0 991973 2472597 1761022 0 0 1719655 0 0 1319514 1297384 1354020 1487841 803231 0 1408813 1482950 1331319 1788217 0 1978756 1772984 0 0 0 908557 0 0 1255399 1156555 0 0 0 0 833743 0 629938 1194542 0 804932 1650084 997270 0 0 1251696 0 0 897703 816655 985651 634334 557776 0 805189 723709 548272 1560703 0 1470070 910475 0 0 0 803674 0 0 722124 1726122 0 0 0 0 795703 0 362603 307722 0 1387784 528170 274592 0 0 315711 0 0 681591 287486 261369 1225145 409350 0 583152 697263 126251 513231 0 655113 443458 0 0 0 414160 0 0 74132 373373 0 0 0 0 681204 -AAAIC(Carbamidomethyl)GADMK MGYG000000258_00350;MGYG000002528_01331 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,2493N@186801|Clostridia,27TH1@186928|unclassified Lachnospiraceae 0.5 186801|Clostridia 1.0 E 1.0 Glucose dehydrogenase C-terminus 0.5 - 1.0 - 1.0 1.1.1.103,1.1.1.14 0.5 ko:K00008,ko:K00060 0.5 ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100 0.5 M00014 0.5 R00875,R01465,R01896 0.5 RC00085,RC00102,RC00525 0.5 ko00000,ko00001,ko00002,ko01000 0.5 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-threonine 3-dehydrogenase. | L-iditol 2-dehydrogenase. TDH. | sorbitol dehydrogenase. Acts in concert with EC 2.3.1.29 in the degradation of threonine to glycine.-!-This threonine-degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex.-!-In aqueous solution, the product L-2-amino-3-oxobutanoate can spontaneously decarboxylate to form aminoacetone. | This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + H(+) + NADH. | L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 0.5 0.5 0.5 0.5 Glycine, serine and threonine metabolism;Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 993377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAIELIK MGYG000003266_00144;MGYG000000188_00406;MGYG000000802_00030;MGYG000001086_00655 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1925@1|root,COG1925@2|Bacteria,2H0K7@201174|Actinobacteria,4CWQ1@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 PTS HPr component phosphorylation site 1.0 - 1.0 - 1.0 - 1.0 ko:K11189 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 2262068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2587794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1144473 0 0 0 0 0 0 0 0 0 0 1989206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1362722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1831425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAIGEMTYGAAR MGYG000002281_03314;MGYG000002171_03031;MGYG000000196_02520;MGYG000000013_04059;MGYG000002438_00951;MGYG000000243_01803;MGYG000002549_04632;MGYG000004797_03291;MGYG000001313_00778;MGYG000000105_03290;MGYG000001666_00135;MGYG000002478_00220;MGYG000004876_01712 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,4AMRT@815|Bacteroidaceae 0.8461538461538461 976|Bacteroidetes 1.0 GK 0.8461538461538461 Psort location Cytoplasmic, score 9.26 0.8461538461538461 glk 0.9230769230769231 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Neomycin, kanamycin and gentamicin biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 258108 0 388779 0 295158 159845 291620 243841 249709 0 323730 384280 0 351509 0 297084 0 511724 302739 257819 352652 421580 438568 431983 0 294220 296528 168744 0 162021 0 0 335190 287024 0 302451 313485 360369 400760 0 357565 0 299827 324145 418841 408283 456465 349942 246875 268135 384617 301152 0 174867 0 172573 548006 519357 543182 304306 359205 322448 0 432117 370459 1168619 0 376896 0 0 500551 518627 0 474857 583869 580171 1212196 0 1739426 0 1715284 1183649 1358170 1143809 1535797 1018023 1114298 918200 956795 1124602 0 737391 0 1268042 1178303 1495932 1289618 584498 866996 1163250 0 1056832 981278 815239 0 1594732 0 0 1025877 956182 0 1869931 1239599 1136756 352447 0 605546 0 675054 593727 559812 347839 834623 737239 637933 456842 595215 640221 0 654496 0 480981 1049342 535207 760233 505394 0 604430 0 0 582872 709321 0 422153 0 0 617688 0 0 553149 457829 507469 1004393 0 992360 0 1236487 1235279 1056000 802778 953051 941074 609788 1215204 953944 751479 0 1095162 0 288820 1325819 0 765533 704310 0 1027936 0 1059350 1201802 0 0 987298 0 0 556778 431346 0 866041 747593 1007843 -AAAILAARPENK MGYG000002517_02918 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the cysteine synthase cystathionine beta- synthase family 1.0 cysK 1.0 - 1.0 2.5.1.47 1.0 ko:K01738 1.0 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00021 1.0 R00897,R03601,R04859 1.0 RC00020,RC02814,RC02821 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PALP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 cysteine synthase. OAS sulfhydrylase. Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors.-!-Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53.-!-Formerly EC 4.2.99.8. hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine. 1.0 1.0 1.0 1.0 Sulfur metabolism;Carbon metabolism;Metabolic pathways;Cysteine and methionine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 2096865 0 293972 118942 259217 328626 0 0 293006 0 177878 320652 0 1157781 945801 379761 510269 0 0 1039627 2486115 173117 0 367545 798295 1325387 0 0 0 356571 0 0 224666 0 0 1758280 1597423 294085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9713899 0 0 9054916 301523 0 0 0 1549437 0 0 0 0 4508718 2771942 0 935180 0 0 2535667 955721 0 0 0 2477136 5451342 8739687 0 0 4006875 0 0 0 3325674 0 8981464 2136955 0 650514 14507054 10252410 0 10226129 6108645 0 0 403227 0 2219552 14791854 0 477612 1360759 17274398 6615189 0 0 279781 13255993 12812775 0 13106943 553565 634959 606003 0 0 653434 7995894 672748 9693352 578175 0 1007241 611563 13645157 -AAAILDKLGVEYEMK MGYG000000301_01054;MGYG000000133_02573 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3XZ51@572511|Blautia 0.5 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) 1.0 purE 1.0 - 1.0 5.4.99.18 1.0 ko:K01588 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R07405 1.0 RC01947 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 5-(carboxyamino)imidazole ribonucleotide mutase. N(5)-carboxyaminoimidazole ribonucleotide mutase. In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates.-!-In the absence of EC 6.3.2.6, the reaction is reversible.-!-The substrate is readily converted into 5-amino-1-(5-phospho-D- ribosyl)imidazole by non-enzymic decarboxylation. 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1- (5-phospho-D-ribosyl)imidazole-4-carboxylate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 67365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65723 0 91096 0 0 0 0 0 0 0 0 0 0 59693 173299 0 0 110319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76429 0 0 0 0 0 0 0 0 0 93993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70438 0 0 0 0 0 0 0 0 0 609635 663680 908741 835874 0 507117 683952 408616 409145 1065160 1090655 437130 579502 1273057 718193 466489 707228 0 0 0 709774 624603 0 583053 645794 517913 717145 0 1160438 0 658833 1075080 1167347 0 489078 675698 406042 515876 -AAAINIIPTTTGAAK MGYG000001881_00319 genome d__Bacteria|p__Verrucomicrobiota|c__Verrucomicrobiae|o__Verrucomicrobiales|f__Akkermansiaceae|g__Akkermansia|s__Akkermansia muciniphila_A|m__MGYG000001881 1.0 COG0057@1|root,COG0057@2|Bacteria,46S59@74201|Verrucomicrobia,2ITXT@203494|Verrucomicrobiae 1.0 203494|Verrucomicrobiae 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 - 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1221977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAINIVPN(Deamidated)STGAAK MGYG000000205_02269;MGYG000003335_00316;MGYG000000233_00345;MGYG000002972_00451 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.75 186801|Clostridia 0.75 C 1.0 Psort location Cytoplasmic, score 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447079 520944 0 0 0 0 0 448183 438134 0 0 0 0 0 0 0 593835 0 583202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460675 0 0 0 0 0 0 205716 235515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAINIVPNSTGAAK MGYG000000205_02269;MGYG000003335_00316;MGYG000000233_00345;MGYG000002972_00451 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.75 186801|Clostridia 0.75 C 1.0 Psort location Cytoplasmic, score 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1671106 1483025 902833 1418563 839206 982663 1148308 2275419 1160842 1554201 868726 1394595 931138 925305 897079 942570 1252966 235035 696777 900925 1442725 1367217 454859 917241 1285976 995780 1458898 237028 1439492 1182980 495994 991372 741817 1276594 1718585 1617511 1082089 671390 7669481 5988828 3850095 10004706 0 3463577 8361955 7842124 6593867 8848448 4281051 4983082 5110802 6439611 0 3902677 0 822530 5537262 7887674 5853589 0 542302 4859372 5239423 5858276 5531968 696498 8468317 5299207 5581156 3810977 6460706 0 7621782 8817022 5056327 4436412 997751 1806872 405527 653220 283221 597469 623356 1410306 394333 839109 637104 451848 588232 572499 912555 937317 778395 581480 1653685 1233608 718757 1190577 641102 600767 639211 621454 1376836 949403 1013839 989416 559475 1635466 1012782 2038709 1222897 669765 584518 410318 592815 0 0 0 0 0 0 311192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392477 263750 0 0 0 0 0 0 0 480209 553324 306919 172292 0 1335497 2346577 1921116 0 1642588 1657490 2482824 3115708 1593459 2113268 2005375 0 972761 2572817 2212898 2185600 2158361 689411 2121758 1291705 1638903 2411516 995739 3655773 2364022 1481567 0 780537 2921955 1022376 2378605 1377382 2073260 0 1871339 1689777 0 2153118 -AAAINTIAHSTGAAK MGYG000002469_01340;MGYG000001292_00923 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CZ97@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1411858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3224561 3718861 0 0 0 2547187 0 0 0 0 0 0 0 0 0 0 0 10404354 0 0 0 1608314 3287842 3266339 0 2995999 0 5775052 3702422 0 3813839 0 0 0 3918781 0 3195641 0 0 182664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 508534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 870250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAINTIPHSTGAAK MGYG000003683_00168;MGYG000002459_01163;MGYG000000756_01094;MGYG000001490_01234 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CZ97@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 805512 0 0 1074434 0 0 0 0 0 0 117590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1803786 2501816 3782674 0 2042527 3894507 2173386 1697038 0 1933163 2443839 0 7710181 1204103 0 2423094 0 9468343 0 0 0 1925403 2627586 6824319 1868871 1587427 1643413 6042706 2608892 0 4805510 0 3393916 2502741 2114096 0 1755700 4650468 848860 1956081 677675 0 0 387366 0 1065418 0 779579 610112 0 803377 447718 0 1147453 0 193383 0 0 0 1431517 176500 0 590697 612397 1098271 1153311 509557 0 330215 0 1967258 1525961 1518205 0 561970 472052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAISTGAK MGYG000001346_02120 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,2FME7@200643|Bacteroidia,4AKME@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin 1.0 oorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00175 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 903376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2850139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAISTGC(Carbamidomethyl)K MGYG000000243_01840;MGYG000004899_00389;MGYG000002455_01429;MGYG000004797_02543;MGYG000002478_01476;MGYG000004876_03121 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,2FME7@200643|Bacteroidia,4AKME@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin 0.6666666666666666 oorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00175 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 1448124 1084442 2554764 1836526 785315 1219434 2099153 493352 1884908 597704 0 342705 1549257 590358 0 493218 0 0 528422 1249823 1994124 509969 604950 2100740 1426056 1906890 1966074 0 1426911 748884 2180601 1430312 3423738 480011 0 1918137 1673563 2469826 0 0 0 0 353395 527609 0 0 0 0 0 0 1398020 754970 0 900496 0 0 840237 893075 770721 641782 0 0 0 0 0 0 652889 717019 0 0 0 0 0 0 0 523966 150247 119297 173206 82790 62325 130329 0 0 265985 149581 0 78957 111001 0 0 0 0 169753 227579 188935 97561 196700 56489 552684 0 390959 518166 0 375108 0 0 324144 0 57298 0 98718 135049 135626 394501 270023 169851 0 290159 202066 163759 295008 236980 321158 0 0 124794 553313 0 101947 0 413143 501589 525746 0 0 0 0 268355 317577 0 501559 186136 167663 0 220726 242439 477087 0 0 221337 0 949952 592864 876955 708697 1070505 1243342 1481949 981725 1530791 181205 0 931335 1084952 592196 0 1175663 0 1304473 1260354 1144851 705027 878730 368162 1208257 1198184 1836990 909357 126859 1235968 1066677 1770371 735727 608041 1362405 0 1726950 1874613 1190688 -AAAIVTNR MGYG000002494_00968 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate 1.0 ppsA 1.0 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 1.0 2.7.9.2 1.0 ko:K01007 1.0 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 1.0 M00173,M00374 1.0 R00199 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160 1.0 Intein_splicing,PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate, water dikinase. pyruvate,water dikinase. - ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAKTETVKDTAAETK MGYG000000076_01972 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia intestinalis|m__MGYG000000076 1.0 2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 173388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 558063 0 0 0 0 0 0 395877 0 0 0 566534 0 0 0 0 0 0 464818 0 0 0 0 0 689235 692647 0 0 0 0 0 0 0 0 0 0 541514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAALAAADAR MGYG000002323_02346;MGYG000001302.1_01840;MGYG000002415_02605;MGYG000000093_03243;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206;MGYG000002534_02768;MGYG000003883_03730 domain d__Bacteria 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 0.8888888888888888 C 0.8888888888888888 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.6666666666666666 adhE 0.8888888888888888 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 0.8888888888888888 1.1.1.1,1.2.1.10 0.8888888888888888 ko:K04072 0.8888888888888888 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 0.8888888888888888 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 0.8888888888888888 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 0.8888888888888888 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 0.8888888888888888 Aldedh,Fe-ADH 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 0.8888888888888888 none 1.0 3215553 3477574 4520840 2599046 2064233 13666351 4071204 3296217 2438300 3589759 1095129 2154760 1470674 3121115 2454750 1245219 1835491 0 2279825 3250700 3166851 14672284 0 13378778 3692433 2257396 2538294 0 3530038 3340620 2287215 2869247 4522779 3452808 4358092 2393737 3126510 4617229 62037313 69578930 77119213 43883144 58881771 86561138 70499659 33926506 63246263 62529791 15880986 37231262 27230395 61574903 49150128 36543487 72324100 0 72446539 49804702 71256936 108276081 0 85382007 68635808 50383261 38500572 0 86319010 63839106 23919671 32059834 82175386 56109795 50037721 50336308 53870785 63400878 4959265 4687426 7598748 4250068 3726102 20691302 4987032 5818874 3374931 5123489 3081266 2179731 4289601 3690001 3615326 4237620 3301256 0 4185748 0 3741741 16951644 0 17102858 4923684 3391692 5159393 0 3624926 4064393 3849843 3250886 8215040 6745440 3306923 0 3299387 7623448 6723046 3001993 6103013 4983947 3404780 7571818 4973659 5728887 3703844 5008436 2169549 3014042 3678522 4912652 4335857 3535671 2927623 0 3598520 4728966 4401889 8864164 0 4864967 4952329 4095118 6167001 0 3062400 4420584 1596522 2529640 5680649 8941572 9163455 7223090 3938924 4019400 109989 90102 182342 0 310507 0 0 120812 0 0 0 0 0 0 0 0 0 0 0 0 0 346650 0 0 0 0 97082 0 0 0 0 0 0 0 0 0 580079 0 -AAALEKVK MGYG000000233_00634 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,220M9@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Binds together with S18 to 16S ribosomal RNA 1.0 rpsF 1.0 - 1.0 - 1.0 ko:K02990 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3329811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3647310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAALETDVVEK MGYG000004876_03560 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__|m__MGYG000004876 1.0 COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,4NGF6@976|Bacteroidetes,2FNTX@200643|Bacteroidia,4AKY2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Psort location CytoplasmicMembrane, score 10.00 1.0 nhaA 1.0 - 1.0 - 1.0 ko:K03455 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 2.A.37 1.0 - 1.0 - 1.0 Na_H_Exchanger,TrkA_C,TrkA_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1758996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAALKPGEVLLLENLR MGYG000003693_01612;MGYG000001306_01732;MGYG000002556_00160;MGYG000001599_01138;MGYG000002478_02340 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NIEK@976|Bacteroidetes,2FMAP@200643|Bacteroidia,4AKI4@815|Bacteroidaceae 0.6 976|Bacteroidetes 1.0 T 0.6 Psort location CytoplasmicMembrane, score 0.6 - 0.6 - 1.0 - 0.6 - 0.6 - 0.6 - 0.6 - 0.6 - 0.6 - 0.6 - 1.0 - 1.0 - 1.0 HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.6 0.6 0.6 0.6 0.6 none 1.0 0 0 0 0 0 0 0 0 0 0 96105 308855 0 0 0 0 0 95798 0 0 0 0 210154 0 0 0 0 76443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 551603 506956 0 0 0 0 0 968768 0 0 0 0 1421986 0 0 0 0 1252664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117803 236397 0 0 0 0 0 331707 0 0 0 0 71284 0 0 0 0 249948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151750 104592 0 0 0 0 0 107662 0 0 0 0 128788 0 0 0 0 61283 0 0 0 0 0 0 0 0 0 0 -AAALLGK MGYG000001502_02294 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Intestinimonas|s__Intestinimonas massiliensis|m__MGYG000001502 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,267UV@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAALNIVPN(Deamidated)STGAAK MGYG000000205_02269;MGYG000001303_01883;MGYG000000233_00345;MGYG000001496_01122 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.75 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 701351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAALNIVPNSTGAAK MGYG000000205_02269;MGYG000001303_01883;MGYG000000233_00345;MGYG000001496_01122 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.75 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5071814 0 0 0 0 0 0 0 0 0 6164324 0 5200537 0 0 0 0 2779568 0 0 0 0 0 0 0 0 0 0 0 9043641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471645 0 0 0 0 0 0 0 2802199 0 0 0 0 0 0 0 2815557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1877558 0 0 0 0 0 0 2771071 0 0 1518321 0 -AAALQLK MGYG000002867_00481 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900552955|m__MGYG000002867 1.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia,22U1P@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Bacterial trigger factor protein (TF) 1.0 tig 1.0 - 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAALQPGEALLLENLR MGYG000002438_03839;MGYG000001489_04176 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,22WBD@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14179812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16029107 0 0 0 0 0 0 0 0 16113959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAALQPGEVLLLENLR MGYG000000196_04506;MGYG000000013_01224;MGYG000003681_00986;MGYG000002549_02739;MGYG000001661_02348;MGYG000003922_03393;MGYG000004876_02584 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2348550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15939497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16403880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAALSQDDK MGYG000000251_00650 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter saccharivorans|m__MGYG000000251 1.0 COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase delta subunit 1.0 acsD 1.0 - 1.0 2.1.1.245 1.0 ko:K00194 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2058015 0 0 0 0 0 15186338 0 0 0 0 36377799 0 0 0 0 32636038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 695508 0 0 0 0 0 0 0 0 0 0 524496 0 0 0 0 889517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 508044 0 0 0 0 0 0 0 0 0 273729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252500 0 0 0 0 0 0 0 0 0 0 347791 0 0 0 0 148804 0 0 0 0 0 0 0 0 0 0 -AAALTQAK MGYG000001306_00758 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,4AK9W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrA 1.0 - 1.0 1.6.5.8 1.0 ko:K00346 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQRA,NQRA_SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309725 0 0 0 0 484079 0 0 0 0 643247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1772760 0 0 0 0 3527302 0 0 0 0 3948786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34388 0 0 0 0 282765 0 0 0 0 710618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175233 0 0 0 0 396986 0 0 0 0 348692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596376 0 0 0 0 367478 0 0 0 0 145021 0 0 0 0 0 0 0 0 0 0 -AAAMLGKPIEELK MGYG000000099_02082 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,267UV@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAMSGAVGIR MGYG000002274_02046;MGYG000004679_00371;MGYG000002619_01820;MGYG000000195_01824;MGYG000002040_00364;MGYG000003166_00931;MGYG000000022_01123 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,3WJ12@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) 1.0 nanE 1.0 - 1.0 5.1.3.9 1.0 ko:K01788 1.0 ko00520,map00520 1.0 - 1.0 R02087 1.0 RC00290 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 NanE,PTS_EIIA_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 N-acylglucosamine-6-phosphate 2-epimerase. N-acetylmannosamine-6-phosphate 2-epimerase. - an N-acyl-D-glucosamine 6-phosphate = an N-acyl-D-mannosamine 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409920 0 0 0 0 429571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1501560 0 0 0 0 1608865 0 0 0 0 2027686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2665203 0 0 0 0 2748789 0 0 0 0 1857452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1129607 0 0 0 0 1569672 0 0 0 0 1176609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1886461 0 0 0 0 1475451 0 0 0 0 1804926 0 0 0 0 0 0 0 0 0 0 -AAAMSIIPTTTGAAK MGYG000004769_01658 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H298@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 911926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 953406 0 1068968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAN(Deamidated)ATGYDVVLGTSSK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 497764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 717898 0 0 0 0 933644 0 0 0 0 407551 0 0 0 0 368027 0 0 0 0 512121 -AAAN(Deamidated)ATGYDVVLGTSSKK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635024 854777 0 0 0 0 0 0 -AAAN(Deamidated)ESFGYNEDEIVSSDIVGM(Oxidation)R MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAN(Deamidated)ESFGYNEDEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANAPEQEYR MGYG000000271_02405 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Myosin-crossreactive antigen 1.0 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 1.0 none 1.0 294185 0 0 0 0 394864 170890 0 222983 0 814968 629107 0 0 0 0 0 0 128278 148369 0 284116 0 287350 195204 281969 0 0 0 1332248 0 0 0 0 0 0 302627 0 169788 0 0 0 0 0 0 0 224228 0 0 181924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116385 0 0 159070 0 0 0 0 0 0 0 0 0 0 0 0 0 117622 0 0 0 0 0 0 0 0 0 0 134686 0 346135 0 0 0 0 615327 479888 0 395371 0 450019 1252127 0 0 0 0 0 0 594639 383212 0 449039 0 837883 485056 573270 0 0 0 672088 0 0 0 384229 0 0 423147 0 -AAANATGYD(Cation_Na)VVLGTSSK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1097135 0 0 0 0 0 0 -AAANATGYDVVL MGYG000001338_03066;MGYG000001338_03061;MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.6666666666666666 2|Bacteria 0.6666666666666666 S 0.6666666666666666 peptidase inhibitor activity 0.6666666666666666 - 1.0 - 1.0 3.4.24.40 0.6666666666666666 ko:K01406 0.6666666666666666 ko01503,map01503 0.6666666666666666 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.6666666666666666 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Cationic antimicrobial peptide (CAMP) resistance 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANATGYDVVLGT(Thr->Ala)SSK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2963902 0 0 0 0 0 1561497 0 0 0 0 0 0 2779973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANATGYDVVLGT(Thr->Ala)SSKK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 0 0 0 0 3353401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANATGYDVVLGTD(Asp->Gly)SK MGYG000001338_03066;MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 0.5 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 0 7500133 3618366 0 0 2499828 0 2769525 0 0 4529909 2944667 3439083 0 2234761 0 0 0 0 0 0 2718829 6023168 3810675 0 0 2958158 3804639 0 2945657 10499287 0 3740664 0 0 0 0 0 0 0 5785880 0 0 5241241 0 5690574 0 6004810 11524714 5451823 0 0 5722204 7102471 0 10896667 0 0 0 5471673 0 6046811 0 0 6031697 13036986 0 1684419 0 0 7270069 0 0 0 0 0 0 0 3507104 0 0 3284534 0 0 0 1899955 3704036 0 3121080 0 0 0 0 3186518 0 0 0 2338260 2442384 0 0 0 1451986 2611694 0 1611101 0 0 3176586 0 0 0 0 3464338 0 0 0 0 0 844368 0 1765597 0 0 0 0 1814935 0 1206910 815069 0 0 0 0 0 0 0 503762 0 0 904380 0 0 0 0 0 2377061 0 0 0 0 1181319 0 0 0 0 0 0 0 0 0 668133 0 0 1402175 0 0 0 0 0 0 0 0 0 2550641 0 0 0 0 0 0 0 0 0 2569804 0 0 0 0 0 -AAANATGYDVVLGTD(Asp->Gly)SKK MGYG000001338_03066;MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 0.5 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 0 6187757 0 0 0 2064201 0 1920139 0 0 3575061 0 2371925 0 0 0 0 0 0 0 0 0 3234285 0 0 0 2709528 0 0 0 9437468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4096563 0 0 0 5022742 0 7524721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2177632 0 0 0 0 978168 0 0 0 0 1791755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920835 0 0 0 0 0 0 0 0 633943 2506252 0 0 0 458047 530991 0 0 0 0 1110378 0 0 0 0 0 -AAANATGYDVVLGTD(Asp->Ser)SK MGYG000001338_03066;MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 0.5 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 903676 0 0 1995946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANATGYDVVLGTDSK MGYG000001338_03066;MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 0.5 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 268247 207923 203528 209243 81138 0 375654 144217 0 228088 0 165154 0 0 184420 201014 204803 0 220870 119044 0 334692 229140 235641 127241 307085 225962 0 0 0 226530 303508 0 222711 0 0 111194 0 426760 0 259695 414381 217391 421106 252934 485893 0 294830 133186 595639 411284 0 370873 436585 373087 0 297645 316035 0 705575 569171 0 378302 281251 86716 807168 0 0 204955 250066 162018 278758 0 0 473857 279643 433909 730477 765809 407473 1331414 839875 590448 366927 0 567095 708279 973713 765879 0 350939 877974 474396 1394401 0 450297 0 481078 947104 1044019 446847 578700 435001 939235 0 0 1509909 965847 536149 346820 0 0 663859 589755 106434 0 137230 257235 126073 253434 121529 0 0 0 214249 0 282952 0 0 134072 118748 0 0 0 0 0 342770 0 0 118618 96630 0 0 0 98269 265358 0 234625 0 0 128040 0 1088833 4320606 2559065 1261907 3105403 1401538 1199809 1536386 0 1073263 1727933 1279703 2890463 0 986452 1964970 1104327 2399677 1102101 1322837 0 1236273 2229562 2173463 1099050 1216525 1244803 1774681 0 0 4179869 6398447 2467608 1540142 0 0 1426376 2966492 -AAANATGYDVVLGTDSKK MGYG000001338_03066;MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 0.5 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 343727 0 0 0 322642 592717 0 0 0 0 0 0 0 0 0 0 116108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553685 0 288212 0 0 87387 126549 0 0 0 0 0 324922 174167 99644 0 0 283992 207160 0 0 0 0 170415 0 0 0 237588 0 0 0 0 76423 182725 0 417903 0 0 226534 0 226053 348757 747487 319564 757782 452033 0 0 0 0 373866 363794 618349 0 0 669463 793756 617495 0 0 0 0 801978 422177 524050 374373 0 507501 0 0 1242515 1021836 958910 493429 0 0 347380 299745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 982399 3303550 1921583 982518 2418068 1256048 0 0 0 0 1451704 1197314 1338660 0 0 1651315 1596022 1244119 0 0 0 879962 1409931 1362879 859084 913388 0 1169697 0 0 2944022 4243115 2035845 1031476 0 0 756245 1911903 -AAANATGYDVVLGTS(Ser->Gly)SK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 2612041 0 0 0 4048356 0 0 0 0 2660712 0 0 0 0 0 3324142 3055533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12119300 0 0 0 0 0 0 0 25379992 0 0 9607977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17055775 0 0 5393448 0 0 0 0 0 22461041 0 0 0 0 5216687 5357608 1613836 0 0 0 7817023 0 1769889 1412581 0 0 0 0 0 0 0 2456821 1734652 3491970 1354282 0 0 0 0 0 0 1867359 0 0 0 0 0 9548539 0 0 0 0 1570512 0 0 5933070 0 0 0 0 1260787 0 0 978195 1645501 0 0 0 0 1024205 816041 511083 1071490 0 0 0 913783 0 0 1562508 0 0 0 0 2398394 0 0 0 0 0 0 0 991616 3775196 2731356 913509 0 0 903029 1112327 0 0 0 1202248 0 0 0 0 895055 0 952851 0 0 0 0 0 0 1453959 0 2306787 0 0 3987387 0 0 1185008 0 0 1218075 0 -AAANATGYDVVLGTS(Ser->Gly)SKK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 2424577 0 2966869 2871518 0 0 0 0 0 2276849 0 2404498 0 0 0 3105039 0 2164568 0 1832619 0 2727444 0 3354584 0 1778364 0 2541251 2520321 0 0 9264030 3801568 0 0 0 2035167 4108888 5721032 0 4319636 4175053 7485613 3559781 0 0 0 3738680 7682312 0 5703998 0 0 0 0 0 0 3567111 0 4664943 7115295 3506267 0 4225098 0 6196969 0 0 0 14530896 4284003 0 0 0 4065086 3941680 808972 6819555 0 1411267 4904938 2216120 0 0 0 1144240 2728520 1430641 0 0 0 2001340 0 2786494 0 566049 0 1498880 2475001 2129173 0 1040183 0 2313102 1362993 0 6064798 8143173 2281423 0 0 0 985615 2164020 364403 716247 0 0 172990 0 0 0 0 0 0 1045668 963834 0 0 0 0 0 0 0 0 0 0 0 0 833067 0 0 0 0 0 2564935 0 0 0 0 439180 0 1678462 5630123 2931727 1457106 3776501 1687898 0 0 0 1299105 2335293 1673036 2485730 0 0 2331720 0 2332770 0 1555006 0 1344382 0 2008454 0 1383177 0 2011987 1618361 0 4812781 6972624 2444767 0 0 0 1218286 3682967 -AAANATGYDVVLGTSS(Ser->Gly)K MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3806621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4531401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1183467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1013364 0 0 0 1866485 0 0 0 0 0 0 0 3267315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1986948 0 2690352 0 0 0 0 0 0 2273118 0 0 0 0 0 584750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1522303 0 0 0 0 0 0 0 0 0 0 0 0 1307112 0 0 0 0 0 0 0 0 3373515 -AAANATGYDVVLGTSS(Ser->Gly)KK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANATGYDVVLGTSSK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 313507 656960 405350 211321 342257 545151 360441 300559 0 0 486200 399946 541869 113318 389177 354709 379306 388189 594554 202524 0 145194 292671 346375 317607 265846 177376 752557 448491 0 284969 385571 290765 289205 0 201482 399905 331945 455164 576565 332041 675573 348333 275839 619227 400099 0 0 665863 77133 429000 284682 389117 429636 0 388078 0 459276 0 180100 188942 533783 270816 555671 483733 343948 449186 0 858575 329178 255648 446520 0 616139 373080 332730 695950 6443044 1306328 1143364 2936970 1544944 258642 840497 0 0 1743849 2820887 1492451 779632 685282 1599324 1069600 3400345 985655 545648 0 1706295 2748282 1653460 883716 900955 0 2580595 496420 0 2797732 5338637 1319239 524831 0 540343 276031 1291795 387886 335084 596481 301812 460529 312566 436959 323620 0 0 340873 451159 342803 394449 307316 380627 454614 0 285582 502897 0 0 0 462505 232382 338352 273591 267879 200682 0 569564 395653 624022 310088 0 0 218971 0 6313634 0 18761703 7615871 19830379 8279260 5983683 9222815 0 0 10313009 7163383 18763620 5689239 6076925 12043958 7612569 16399816 5984604 6799097 0 8107167 14902693 11141097 5877024 7337344 6156024 13796345 7394434 0 27921625 0 14922816 8447172 0 6102920 7710757 23345111 -AAANATGYDVVLGTSSKK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241941 221524 302920 322633 0 105937 221432 202200 0 0 0 0 0 0 177496 344331 0 233391 0 107795 0 0 332731 0 0 0 0 102351 0 223919 0 0 199842 175303 0 0 0 0 129561 0 2353197 401987 384775 773031 604451 491872 424144 0 0 560378 782720 444163 450068 391185 576947 352683 1234538 409360 441597 0 508105 1135542 632598 286331 318941 494705 1045951 388521 0 1213583 2375379 561498 471477 0 368736 215093 425890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3847003 18010849 9671636 3877653 9857247 4107963 3473744 3188647 0 0 5123821 4134749 6918508 2322371 3276422 6240788 2989575 6014247 2955224 3179469 0 3285171 5604805 5061296 3060959 2881899 2656322 5900459 3555096 0 12923642 17178615 6489082 3532620 0 2665455 3215020 10474594 -AAANE(Cation_Ca[II])SFGYNEDEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 567576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 735964 0 0 0 0 0 0 0 0 0 0 552466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1012269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANE(Cation_Fe[II])SFGYNEDEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446089 0 0 0 0 0 224030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANE(Cation_Na)SFGYNEDEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1366972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGY(Amino)NTDEIVSSDIVGMR MGYG000000223_00996 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,3VP0T@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 647777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGYN(Deamidated)EDEIVSSDIVGM(Oxidation)R MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 562342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585755 0 0 0 0 0 0 835073 0 0 0 0 803266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1356748 0 0 0 0 0 0 1209110 0 0 0 0 1961970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1005703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGYN(Deamidated)EDEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 752870 0 0 0 0 0 398985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1446836 0 0 0 0 0 512769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3572436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGYN(Deamidated)TDEIVSSDVIGM(Oxidation)R MGYG000003001_00320;MGYG000002052_00078 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGYNE(Cation_Ca[II])DEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 418533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221512 0 0 0 0 0 0 0 0 0 0 0 0 0 127139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588953 0 0 0 0 0 0 760760 0 0 0 0 0 0 719806 0 0 0 0 0 0 0 0 691601 0 0 0 0 0 0 0 0 0 0 748706 0 0 0 0 0 0 0 0 1523579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGYNE(Cation_Fe[II])DEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 384856 0 454156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 893848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGYNE(Cation_K)DEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 123835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGYNE(Cation_Na)DEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 1807701 0 0 0 0 0 0 0 0 0 1301846 1249359 0 0 0 0 284422 0 0 0 0 0 1131793 0 0 0 0 0 0 739339 1756349 0 0 1576283 0 0 0 0 0 791845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1539158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2167541 0 0 0 0 0 0 0 0 0 0 0 0 920064 0 0 0 0 0 0 0 0 3125012 0 0 0 0 0 0 0 0 0 0 1895510 0 0 0 0 0 0 564779 0 3713904 3383433 0 0 0 0 0 0 695870 1264298 0 1431908 0 0 0 0 0 0 1143189 0 2186671 0 0 0 0 1611803 0 0 2722657 0 1842016 2631385 0 0 2002644 0 0 0 0 0 0 0 0 6441692 3198939 0 0 0 0 3088664 0 4076251 0 0 4906726 0 0 -AAANESFGYNED(Cation_Ca[II])EIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 517992 0 402134 546003 0 383266 445428 594990 0 601756 552123 692209 358526 370705 373715 0 544411 192008 381081 347588 0 327085 235878 179306 0 358902 470656 334769 0 743718 260769 0 203131 555234 486658 377966 517286 181960 147513 0 148748 190653 0 135262 363353 154588 110338 0 176868 131221 114432 106134 169218 0 113406 826982 57216 206109 0 0 254537 238967 0 101687 170800 666624 0 149955 129581 0 154093 167874 222703 184058 140739 113293 658982 0 730192 537066 0 474824 501508 0 392560 481723 661342 732005 614097 587529 719210 0 543641 221872 0 0 0 544965 496499 332962 0 621515 0 719516 0 682880 402414 0 1222045 0 693766 398971 585478 1018983 1347560 0 384873 1581304 0 532564 825545 1638904 1563001 731254 709971 745642 512728 1291138 1342586 0 1012851 113448 1166601 1200214 0 454485 270268 330546 0 1439199 1335467 252682 0 1000547 557881 0 367374 582451 1153904 1074333 1376505 394787 816608 0 827527 0 0 699974 586934 432301 880039 0 1025326 617876 268123 1306101 1158830 0 0 81305 0 767574 0 1371896 69029 901156 0 611455 1204589 257896 0 762890 625793 0 1029887 0 15270 541272 6485 0 -AAANESFGYNED(Cation_Fe[II])EIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 515520 0 214117 0 0 376869 464713 667711 519845 625966 573369 665170 0 412134 374949 211056 345880 141694 536363 394271 426799 337067 209112 175312 460592 208971 0 197947 0 656957 0 242566 274064 563961 490457 332849 584351 200334 150379 0 112062 0 0 85389 227270 188812 57683 0 201504 69325 0 0 148222 227451 498133 724885 56847 0 0 105157 214815 0 78192 112514 0 622371 0 0 0 106058 52182 109572 273924 225783 176783 114257 552687 0 513332 0 0 462590 330063 0 215061 387149 444678 545479 0 438246 566238 606158 402547 0 250710 454255 401328 463433 366486 382017 515195 560214 0 370678 0 306896 0 299862 920343 0 698651 327956 579898 0 0 0 278513 0 0 435208 846934 1346016 0 616885 581610 687107 0 1113400 0 789873 870707 173941 0 1057112 1028418 264946 95026 201769 1424798 1203225 0 125279 0 0 0 406879 260855 508452 913689 919151 0 352872 0 0 727779 0 0 571769 0 408169 583346 0 772801 474692 0 604219 0 524231 890054 0 704663 479458 577414 612393 0 548866 819611 413242 0 151394 0 444997 0 0 1331103 6611 0 1234153 7758 0 -AAANESFGYNED(Cation_Na)EIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1646381 1127075 887051 0 1181688 1008680 1450578 1851117 1438372 1930811 1894837 2070917 1252559 0 0 1012324 1481908 604410 1630347 1195028 1372407 1054014 609977 703807 1545414 0 1556570 965752 0 2028420 709935 715257 0 0 1628383 1293976 0 666117 679682 551949 509166 681824 0 209778 919157 469296 306985 426671 892882 483850 724346 370242 454997 533837 446207 2756101 498317 908057 541654 256286 0 551910 619915 575328 656201 0 0 614861 512064 605496 501590 625293 652710 707985 467682 695116 2233506 0 1941338 1346319 1386397 1300931 1349043 2062460 1095366 1712273 1786595 2667207 1743986 1623716 2069205 0 1615408 768318 2003125 1931932 1456003 1618934 1311721 944081 1938918 2550374 2130899 1630557 0 1819444 1233706 1420902 3599608 2143763 2350335 1177170 2051367 0 4506610 1418844 1423303 4843564 2300050 1834233 2445537 4686385 4219695 2541504 0 2510138 1497839 4504074 4276860 2496490 3205579 0 3792469 0 0 881475 904643 1627201 4363823 3630263 3929869 0 0 3330153 0 1509457 946795 1930278 3508222 3177744 0 0 2707395 0 2341440 136938 1686545 1879221 0 1326329 2460626 0 3976602 0 0 5607933 3873385 0 3031878 298625 2900438 2586515 2051107 6157346 632733 4497083 0 0 5352793 1182091 0 2133750 0 0 0 77535 3608593 0 2941562 1504766 -AAANESFGYNEDE(Cation_Na)IVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGYNEDEIVSSDIVGM(Carbamidomethyl)R MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 654811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 972178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1994568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGYNEDEIVSSDIVGM(Oxidation)R MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 851054 593403 627224 1223926 890968 1273162 760079 780181 1194670 959767 1433577 1545788 0 384320 1317992 0 2139997 1076027 1252607 914320 1001702 1097422 399514 491395 1420177 910106 844439 547625 604658 1075971 377763 544836 409835 1007635 815916 687766 942784 364769 309980 307344 175250 340397 592210 0 272082 0 606853 0 608244 190478 0 212184 295423 321647 0 1685148 0 315112 269898 0 828834 214375 0 177216 326403 1128192 289394 0 417493 0 218270 300101 180436 208916 259775 514577 1856689 2005594 2038806 1923445 1017282 926137 1151194 1582196 1162264 1484970 1463598 1857058 1253111 1278860 1396366 1404965 1179129 630679 1178074 1387911 1018353 942025 1111003 950756 1381385 1905819 1215516 1184858 619412 1311738 984511 1144230 2523815 1341451 1349932 919110 1205756 2180818 2999993 1094156 870082 3671393 1891427 1250938 1723844 3824548 2978936 1709444 1610856 2052779 1128841 4370698 4091260 1625897 2497931 584973 3036379 3288166 3467585 666530 764099 736133 3747528 3874389 3704834 1040081 852736 3517709 1279009 1357895 1067681 1940655 4485748 2545786 4253833 936746 1840616 1746198 2634190 0 1582438 1877970 1753797 1204504 1559745 2441144 1867973 1437345 1306579 2563582 2906370 1215867 1776092 196871 2206494 1497401 1635632 2191550 386180 2250976 2672628 1723780 2734260 590953 516563 1152246 1086017 450226 3140618 2320410 2081330 2209852 2662487 1842715 -AAANESFGYNEDEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 6060616 4179273 3570837 0 4596647 3692943 5465877 6601781 6217972 7763922 6626410 7350743 4561383 4144766 5354184 3940032 6189460 2080276 6058984 4224800 4475647 4029159 2117067 2351856 6927075 4516445 5868113 3489624 3624062 8010157 2510167 2919008 2370015 6263195 4818612 4768175 5107689 2010542 2309149 1629517 1627489 2416922 3383650 1290899 3682763 1962225 1517767 0 2616608 1525662 2135337 1431351 1864040 1995674 1437190 10167390 1464690 3536506 2277976 1227768 5879509 2346531 2433367 2123349 2173760 8193262 2397680 1654917 2157218 1993009 1326700 1953423 2173779 2160428 1708040 2392436 7510194 5869136 7848368 4502897 4280795 4794117 4338899 7813478 4018432 5538228 6853924 9281004 6891502 5226289 7834301 9655099 5455607 2434792 7449924 6799288 5693741 6115467 4821119 3294712 6939973 7824180 8275446 6525485 3585308 5819248 4875964 5359150 12783545 8602971 8331364 3926951 6708831 11879680 16464784 4598751 4146547 16979023 7500569 4965726 9286928 16939558 15626352 8114204 6883780 8207485 4745350 14527995 17718872 8782051 12227004 1730012 14404792 11986237 9383481 3058026 1738225 11485204 14029043 14079946 14375671 2720329 4052257 11418157 4312884 5509243 3661532 6257361 12644958 11516713 15630822 3984718 8830516 7153307 7663196 2375644 4865847 6913256 5404403 3915821 8662986 10363724 38610997 6259644 23088141 71087349 18055025 7693260 13091141 1206955 14183784 11901241 14414058 61300464 3485177 48698499 64119331 19724900 83231950 9989554 15685621 12427272 30393249 10504003 57338722 81205758 151960711 93723338 120097668 87116102 -AAANESFGYNEDEIVSSDVIGIK MGYG000001421_02311 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__Dielma|s__Dielma fastidiosa|m__MGYG000001421 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,268FY@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1019339 0 0 0 0 0 0 0 0 377390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 985782 0 0 0 0 0 0 0 0 1741055 0 0 0 0 0 0 0 0 -AAANESFGYNTD(Cation_Na)EIVSSDIVGMR MGYG000000223_00996 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,3VP0T@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 866818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 982088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGYNTDEIVSSDIVGMR MGYG000000223_00996 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,3VP0T@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 187765 0 0 0 170011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246662 266310 0 227286 0 0 0 0 117155 198142 0 237196 0 0 0 0 0 0 0 608360 0 0 0 373146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3050156 497919 0 621672 0 0 0 0 3866853 3745292 0 491826 0 0 0 0 0 0 0 247081 0 0 0 440118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1838791 724115 0 855626 0 0 0 0 1514680 2791848 0 3079629 0 0 0 0 0 0 0 3688743 0 0 0 1042291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10296901 909686 0 92054 0 0 0 0 0 1302149 0 12110253 0 0 0 0 0 0 0 6815690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1074137 0 0 2844136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGYNTDEIVSSDVIGM(Oxidation)R MGYG000003001_00320;MGYG000002052_00078 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESFGYNTDEIVSSDVIGMR MGYG000003001_00320;MGYG000002052_00078 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 450182 0 0 0 0 0 0 0 0 0 821295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7104318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1388735 1702563 0 0 0 0 0 0 0 0 0 1510107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321461 0 -AAANESYGYN(Deamidated)EDQIVSSDIVGMR MGYG000001310_02090 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESYGYNED(Asp->Asn)EIVSSDIVGMR MGYG000001439_00571 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Faecalimonas|s__Faecalimonas umbilicata|m__MGYG000001439 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 986430 0 0 0 0 0 0 0 0 0 1047051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 201001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321863 0 0 0 0 0 0 0 0 0 1183313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESYGYNED(Cation_Na)QIVSSDIVGMR MGYG000001310_02090 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 708826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESYGYNEDEIVSSDIVGM(Oxidation)R MGYG000001439_00571 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Faecalimonas|s__Faecalimonas umbilicata|m__MGYG000001439 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418179 0 0 0 0 956608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552559 0 0 0 0 0 0 0 0 0 399787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESYGYNEDEIVSSDIVGMR MGYG000001439_00571 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Faecalimonas|s__Faecalimonas umbilicata|m__MGYG000001439 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363404 0 0 0 0 796079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 761152 0 0 0 0 552311 0 0 0 0 907165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403709 0 0 0 0 824581 0 0 0 0 801767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 455116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277290 0 0 0 0 352588 0 0 0 0 0 0 0 0 0 0 -AAANESYGYNEDQIVSSDIVGM(Oxidation)R MGYG000001310_02090 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 352247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 202116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANESYGYNEDQIVSSDIVGMR MGYG000001310_02090 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 2504204 2553254 0 0 0 0 0 0 2800461 0 0 0 0 0 0 0 0 1971021 0 966667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 452293 0 0 0 0 0 0 0 0 321690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 743352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 667447 0 548490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANFNNFQEK MGYG000002438_02937 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,22VYG@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Protein of unknown function (DUF1015) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1015 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 231149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 616337 0 0 913283 467520 1002853 0 764169 0 0 0 0 879004 0 802191 0 1123370 0 0 0 0 0 0 0 0 0 0 0 0 582016 0 612862 0 0 0 0 0 0 411834 0 0 0 281667 420096 0 433221 0 0 0 0 357839 0 493103 0 726328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376518 0 0 0 0 0 0 334113 0 0 0 303732 612543 0 774930 0 0 0 0 286729 0 146189 0 1307787 0 0 0 0 0 0 0 0 0 0 0 0 556914 0 435641 0 0 0 0 0 0 2082915 0 0 2112695 1451670 1629312 0 2199251 0 0 0 0 1769360 0 2040262 0 2917222 0 0 0 0 0 0 0 0 0 0 0 0 1826948 0 1361638 0 0 -AAANNPELAAFIDEC(Carbamidomethyl)R MGYG000002494_00657 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,3WW28@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Leucyl-tRNA synthetase, Domain 2 1.0 leuS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.4 1.0 ko:K01869 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03657 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610 1.0 Anticodon_1,tRNA-synt_1,tRNA-synt_1_2,tRNA-synt_1g 1.0 - 1.0 - 1.0 - 1.0 GH13_26 1.0 leucine--tRNA ligase. leucyl-tRNA synthetase. - ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1380620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAANYLDIPLYR MGYG000003363_02712;MGYG000002033_02968;MGYG000001306_00798;MGYG000002478_03016;MGYG000002438_02238;MGYG000002478_00851;MGYG000000243_01149;MGYG000003367_02246;MGYG000000355_00667;MGYG000002455_01185;MGYG000002438_01170 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 0.7272727272727273 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 1581555 0 1709943 0 0 1152361 0 0 0 0 0 0 1324889 1267473 0 0 0 1208740 1582281 1325781 0 0 2079893 1579576 0 1304390 0 1867357 1504863 0 0 1073491 0 0 1046823 0 0 0 2847018 3067502 0 4239633 0 0 2800480 0 0 0 0 0 3863385 3611032 0 0 0 5207921 0 0 0 0 7647929 3068264 3591883 0 0 6574487 3835200 0 3245480 0 0 0 0 0 0 0 0 2236695 2849726 0 0 0 2332814 0 2386304 0 0 0 0 0 1760843 2306803 0 5808344 1863777 1660435 0 2067195 5797651 2695614 0 1919845 0 5307481 2467706 0 0 1980815 0 0 2122845 0 0 0 0 283606 0 203022 0 286654 0 0 0 0 0 0 387410 0 471673 283627 0 0 0 391205 0 0 0 0 452393 0 917221 0 0 0 645084 297535 393337 0 357792 0 905732 0 0 0 0 0 0 0 1236377 0 0 843954 1299775 0 0 0 0 1783115 0 4761989 1440430 0 0 1302960 4239934 0 0 0 1676829 3598689 0 0 0 0 1041649 0 1965041 1825575 0 1716292 -AAANYLDLPLYR MGYG000001306_00798;MGYG000003312_00286;MGYG000002438_02238;MGYG000002478_00851;MGYG000001461_01176;MGYG000002455_01185;MGYG000001641_01230;MGYG000003363_02712;MGYG000003351_05187;MGYG000002033_02968;MGYG000003701_04731;MGYG000002478_03016;MGYG000000243_01149;MGYG000003367_02246;MGYG000000355_00667;MGYG000002438_01170;MGYG000000098_00210;MGYG000000013_00888 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 0.7777777777777778 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 1599105 0 1501806 1279350 0 1880788 1346755 1493571 1442729 1930038 1592373 692831 1014761 1185084 1315237 1387472 0 0 0 1312030 1219760 0 1220190 1283965 1100273 1466757 0 2079134 1211866 1681601 0 1543139 1488362 0 1682885 1307039 1466144 0 912201 2901308 1559327 4183900 3485764 0 4073946 3487693 3612620 3664315 3982480 0 1329988 4625418 4626753 3203528 0 3622610 3523640 4982339 3735403 0 0 0 5139272 3279910 0 0 3581302 877009 4838523 3343258 3279957 3192906 2959333 3151324 2762582 1724915 0 0 1979131 3330489 2966908 0 1700148 0 1803799 2423734 3069656 1805490 2113554 0 869235 1606411 0 0 0 1710198 0 0 0 1808598 0 1882325 0 0 2172017 3167951 843113 1990551 1639115 0 2668834 2077252 2606328 535225 834637 217425 612677 215175 662001 321063 521622 380276 353991 464844 927808 717685 311611 734289 691031 240464 0 477496 671637 3497980 818941 0 519109 967891 613566 565816 0 232884 1179960 0 1130808 667625 706702 855799 536158 522756 475684 1392713 1033053 1228144 1720325 2515205 1794472 0 2053607 1819951 809238 0 1382104 1701750 1405062 1436859 0 1723994 0 0 2006946 3251459 1663347 0 1713364 1595903 2117680 333551 0 1913342 3886349 1833368 1374491 0 1843363 0 798110 2012721 0 -AAAPAAAAPK MGYG000002492_01473 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 791481 0 0 0 0 297380 0 0 0 0 493787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4162099 0 0 0 0 3563315 0 0 0 0 3607277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1305920 0 0 0 0 1674744 0 0 0 0 2397407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428334 0 0 0 0 0 0 0 0 0 930634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76443 0 0 0 0 204430 0 0 0 0 61539 0 0 0 0 0 0 0 0 0 0 -AAAPAAAPAAKPAAAAGAGSVK MGYG000002517_01656 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920373 0 1086901 0 0 1097103 0 0 945916 1118856 1061545 0 0 0 0 0 939380 0 0 0 0 906399 0 1024867 0 1157964 0 0 0 0 658332 0 1129042 1003331 0 1641843 853113 904987 -AAAPAAEAPAAK MGYG000000179_03221 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24R6P@186801|Clostridia,220KI@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 132342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1047867 0 0 837012 468640 0 0 0 992760 0 587495 610231 847682 1170768 1290578 850849 0 0 794668 1148627 1101815 0 0 0 0 0 1633257 0 1164177 1075390 0 0 0 0 0 1609170 418150 0 0 0 218959 247596 411036 0 0 0 114960 543934 0 355417 183514 411263 572165 141544 0 0 0 199496 219932 342029 0 473570 0 484417 294621 0 0 290914 316264 0 0 0 0 518468 367098 556846 13290784 0 3672459 6333029 8670391 3867822 0 4053702 6133198 7515204 2862747 5721816 2748890 11658690 9438026 5575618 9761693 0 5616288 15386504 4413063 5961904 0 8412068 4037408 16510606 9708051 0 11699547 5567978 3395676 0 5159591 0 0 14128251 11212668 6818706 -AAAPAAGAGAVK MGYG000001338_01632;MGYG000000133_01634;MGYG000000171_00279;MGYG000000213_01127;MGYG000002298_00907;MGYG000000200_00817;MGYG000000806_02004;MGYG000003012_01442;MGYG000000212_00763 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1518500 2551479 2235815 885740 2959717 2974851 997537 1347308 1163457 1364702 2332104 1684614 2490739 1267206 1644407 2891237 954677 2901865 1894202 1291283 1723718 4663821 1874416 1938176 1588930 1153367 1075634 2137964 3364505 0 2459155 2158809 2063739 0 1415823 989603 1110722 2780262 379693 5437220 471683 590810 938445 467214 525878 668561 492189 373266 802079 285586 905737 398652 191488 184805 304457 2115436 460911 522159 310046 386913 1315677 695322 478362 494356 542032 2372441 2612280 0 4200447 1767082 493778 0 575789 672317 420915 0 548359 5783804 952832 266985 0 364025 303858 1468645 192474 640148 557009 750181 1063374 391963 855719 1070913 1356761 537070 792406 943479 361396 1002887 934120 0 984659 641287 645604 696020 1373740 0 1815859 3573075 1882139 0 798192 266924 435779 977104 301766 2435885 1694118 469424 1353785 556624 409125 582397 196673 678641 1373439 605332 1079786 503373 913068 1042863 807693 890984 310496 693704 0 1268020 115720 1477333 0 126483 236013 1555805 4639219 0 4185705 1743776 1371890 0 540036 338324 0 2335448 5691805 4621975 4086409 4987671 1262582 2589393 6714645 4752074 2981685 6385754 8283005 4251538 8678947 11093452 6869668 3793667 4939336 1093765 4671025 1525478 5260065 2866978 1576394 3670062 5543288 5526393 7260483 1638956 7012629 0 5417842 5304956 11804122 0 3920652 7534809 3348988 5253171 -AAAPAAGAGSVK MGYG000000142_00945 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1048708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525443 0 1244682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2010017 0 835700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406850 0 457168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAAGGAAAAEEK MGYG000004769_00419;MGYG000004802_00517 domain d__Bacteria 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4H4X8@909932|Negativicutes 0.5 909932|Negativicutes 0.5 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298232 0 0 0 0 0 0 0 0 0 0 0 722659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 666006 0 0 271782 0 0 0 0 0 0 0 202660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241399 0 0 0 0 0 0 0 168590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 235915 0 0 0 0 0 0 0 0 0 0 472015 0 0 0 0 0 0 0 0 0 0 0 698960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 915199 0 0 0 0 0 0 0 519526 -AAAPAAPAAAA(Ala->Pro)K MGYG000003899_00809 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539945|m__MGYG000003899 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1187996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAAPAAAPK MGYG000000271_00470;MGYG000000249_01881 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 0.5 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 0.5 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 482007 0 651830 0 0 0 0 0 0 0 660163 0 0 0 0 0 357669 0 0 406703 0 0 0 0 0 538315 0 0 0 354297 0 0 633201 0 0 0 822821 518016 1361204 0 2547176 0 0 0 0 1126086 0 0 1238028 0 0 0 0 0 5686977 0 0 1006344 0 0 0 0 0 0 0 0 0 779856 0 0 2568217 0 0 0 1137524 2854908 681793 0 1444363 0 0 0 0 421357 0 0 289210 0 0 0 0 0 385553 0 0 230788 0 0 0 0 0 313960 0 0 0 307434 0 0 1157132 0 0 0 523116 1259913 240578 0 941785 0 0 0 0 363500 0 0 276513 0 0 0 0 0 405286 0 0 0 0 0 0 0 0 0 0 0 0 324168 0 0 0 0 0 0 0 923295 290263 0 0 0 0 0 0 154631 0 0 0 0 0 0 0 0 821822 0 0 454394 0 0 0 0 0 522985 0 0 0 768832 0 0 166409 0 0 0 611681 278206 -AAAPAAPAAPKAA MGYG000003166_01306 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539885|m__MGYG000003166 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2107619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAAPK MGYG000000133_01634;MGYG000002042_00590 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 0.5 186801|Clostridia 1.0 I 0.5 Biotin-requiring enzyme 0.5 gcdC 0.5 - 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 0.5 - 1.0 - 1.0 - 1.0 - 0.5 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 141596 179211 377953 260101 0 159297 172824 235176 222822 0 0 288542 201110 0 503769 282975 350405 0 0 0 0 0 0 333356 268488 272002 272583 0 341865 0 0 0 349744 0 0 0 182252 376760 144814 166553 103182 1353668 0 190092 0 0 116055 0 0 1446231 65950 0 0 176158 143342 0 0 0 67950 210639 0 438078 0 0 196708 0 65491 0 335309 0 69354 0 54090 107173 187785 216096 106486 0 212487 0 0 0 0 0 0 0 0 0 0 0 165072 0 125421 0 0 0 0 0 0 0 134541 297653 230212 0 154791 0 0 0 290889 0 0 0 0 144246 126783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143210 0 0 0 0 119612 0 0 0 177199 0 127638 96068 10989742 8216858 11519940 14455000 0 4481086 15915243 6464805 6935695 16440276 20201070 14532252 10567505 22439655 9984082 8363707 7058082 0 12681243 0 13430128 7156767 0 0 13506401 10709911 14276408 0 15078055 0 12319391 11063971 22419602 0 11635306 19029039 7752232 0 -AAAPAAPVAPK MGYG000001300_00242 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 252300 0 0 0 0 0 0 0 0 0 0 0 0 276354 0 0 0 0 486272 263298 0 0 0 107509 151664 149988 0 0 0 0 0 0 0 0 0 0 0 0 1861119 0 2086584 1461169 0 1631446 1900242 2341533 2563515 0 0 1669256 1099808 1678270 0 843260 2485163 0 2370597 1565922 1559776 1140742 0 911245 2006325 1405342 0 0 0 1536723 0 0 2449824 1718891 0 0 2142440 1665227 1211066 0 2136574 1352287 0 2384544 1870280 2461544 152221 0 0 1280546 1571660 1532074 0 270666 1364244 0 1006194 1606335 1676997 1328030 0 1738932 1619812 1431073 0 0 0 1538146 0 0 1794157 1495870 0 0 1246912 1816007 2532828 0 5198705 2544181 0 5296084 4946403 1358247 3496680 0 0 3711964 3510913 2962332 0 3490437 3645842 0 4284936 2500336 2307339 5895636 0 5331883 1986992 3039277 0 0 0 3347064 0 0 5059715 3239561 0 0 2362699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAEEAAAGPSEVTVTLTDVGGTK MGYG000000223_01551 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,36IQP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 314148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391416 0 563922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140199 0 0 0 0 0 0 0 0 0 0 0 0 1524896 0 0 0 0 0 0 0 0 0 979654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369922 0 0 0 0 0 0 0 0 0 0 0 0 798143 0 1563291 0 0 0 0 0 0 0 1040489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609348 0 0 0 0 0 0 0 0 0 0 0 0 153844 0 1693815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAGAAGAVTVK MGYG000000022_01358 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 455157 0 0 0 0 0 0 0 0 0 155890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2141061 0 0 0 0 2130800 0 0 0 0 1909461 0 0 0 0 0 0 0 0 0 0 -AAAPAGAGSIKVEAGAAGK MGYG000002492_01473 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270253 0 0 0 0 0 0 0 0 0 179701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293563 0 0 0 0 269807 0 0 1581117 0 0 0 0 0 0 0 0 0 618821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1415205 0 0 0 0 1126214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAGAQGAVK MGYG000000187_00854 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,25WYH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756338 0 0 5069544 0 0 0 0 4118658 0 0 0 0 4073517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466394 0 0 0 0 551278 0 0 0 0 504065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559742 0 0 0 0 0 0 0 0 0 613537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1054369 0 0 0 0 392590 0 0 0 0 1498405 0 0 0 0 0 0 0 0 0 0 -AAAPAGGAGNVK MGYG000000271_00470 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 229255 0 0 0 0 0 0 0 0 771965 0 0 0 0 0 745891 280503 0 354344 0 0 0 0 564494 1167739 0 0 0 849950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367031 0 0 0 0 0 0 0 0 741594 0 0 0 0 0 574953 788329 0 762338 0 0 0 0 836546 400756 0 0 0 796876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280266 0 0 0 0 0 0 0 0 -AAAPAGGAGNVKIEAGAAGK MGYG000000271_00470 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAKPMGPNDYMVIGLAR MGYG000002494_03382 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1RHH7@1224|Proteobacteria,1RNAT@1236|Gammaproteobacteria,3WY36@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 PTS system sorbose subfamily IIB component 1.0 manX 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0008645,GO:0008982,GO:0009401,GO:0009987,GO:0015144,GO:0015145,GO:0015149,GO:0015578,GO:0015749,GO:0015761,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0022870,GO:0031224,GO:0031226,GO:0034219,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046323,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098657,GO:0098704,GO:0098708,GO:0098739,GO:1904659 1.0 2.7.1.191 1.0 ko:K02793,ko:K02794 1.0 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 1.0 M00276 1.0 R02630 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.6.1 1.0 - 1.0 iAPECO1_1312.APECO1_874,iECOK1_1307.ECOK1_1934,iECS88_1305.ECS88_1869,iPC815.YPO1758,iUMN146_1321.UM146_08085,iUTI89_1310.UTI89_C2014 1.0 EIIA-man,PTSIIB_sorb 1.0 - 1.0 - 1.0 - 1.0 - 1.0 protein-N(pi)-phosphohistidine--D-mannose phosphotransferase. mannose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-mannose(out) + N(pros)-phospho-L-histidyl-[protein] = D-mannose 6-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Phosphotransferase system (PTS);Metabolic pathways;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 160893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480128 0 0 0 0 212050 0 168744 0 0 0 126237 0 0 0 0 0 0 0 0 1060129 1348250 1187859 1502007 0 3323913 1728591 0 823030 2343473 0 0 0 1499761 0 0 2063732 0 2097359 1584765 0 3941197 0 2808386 1642326 1398334 1240018 0 2555717 2221526 0 0 1314397 0 0 1178940 994789 757514 252824 368539 682115 0 0 973463 0 0 0 0 0 0 0 0 0 0 0 0 640288 386451 0 170640 0 160029 0 0 0 0 0 0 0 0 241676 0 0 246030 0 777623 0 481271 0 889183 0 0 0 0 0 646569 0 0 0 810282 0 0 411633 0 600526 347156 0 610472 0 510303 791603 1073608 468742 0 315543 0 0 0 367547 0 0 0 479165 479380 0 0 0 501953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124769 0 0 0 0 0 -AAAPAPAAAPAAAPAAAPK MGYG000004276_00434 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4|s__ER4 sp900550165|m__MGYG000004276 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,2N7T7@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-lipoyl like 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572254 0 0 0 0 723062 0 0 0 507450 703896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAPAAAPK MGYG000000076_00252;MGYG000000245_00298 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3429633 0 0 0 0 0 0 0 0 0 0 1521067 0 0 0 0 0 0 0 0 0 0 0 0 3266323 2085717 0 0 0 2295236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAPAAK MGYG000002506_04250;MGYG000004769_01105;MGYG000002535_03464;MGYG000004769_00268 domain d__Bacteria 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 0.5 1236|Gammaproteobacteria 0.5 I 0.5 glutaconyl-CoA decarboxylase subunit gamma 0.5 gcdC 0.5 - 0.5 4.1.1.70 0.5 ko:K01615 0.5 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 0.5 M00307 0.5 R03028 0.5 RC00832 0.5 br01601,ko00000,ko00001,ko00002,ko01000 0.5 - 0.5 - 1.0 - 0.5 Biotin_lipoyl 0.5 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 0.5 0.5 0.5 0.5 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 0.5 none 1.0 0 0 278478 745506 357816 402853 0 469405 700922 0 517185 416070 418328 309164 0 589738 551107 0 0 3627625 574102 692659 0 414163 0 0 0 0 367885 0 0 447277 377602 0 0 591644 0 468199 0 0 442943 594674 384679 479818 0 753882 376170 0 720219 684773 224725 442628 0 297606 353849 0 0 365314 313647 444010 0 436180 0 0 0 0 421834 358568 0 377449 253869 0 0 319025 0 333401 0 0 170302 85482 159188 143636 0 223777 171864 0 188285 131986 199456 239133 0 159874 0 0 0 186246 347035 154803 0 356846 0 0 0 0 140162 0 0 159761 133624 0 0 210340 0 0 0 0 94655 86594 120636 155893 0 181671 149775 0 314183 68244 228109 156138 0 139182 58309 0 0 110724 140776 156017 0 241860 0 0 0 0 43573 2000146 0 236742 57873 0 0 121048 0 147133 0 0 0 226048 0 0 0 0 260459 0 101543 0 0 168227 0 0 65185 0 0 252729 310893 0 0 86919 0 0 0 0 208047 362892 0 0 0 0 0 0 0 94918 -AAAPAPAAKPV MGYG000004769_01105;MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2235119 0 0 0 0 0 0 0 0 0 0 0 0 1331337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1580894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5878558 0 0 0 0 0 0 0 0 0 0 0 0 3248252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7098403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAPAAKPVAAGAATISAPM(Oxidation)PGK MGYG000004769_01105 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3479748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAPAAKPVAAGSATISAPM(Oxidation)PGK MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 607738 575858 428449 577692 0 0 541866 813859 0 768154 632967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603590 0 650491 0 0 0 0 601969 0 517790 378555 0 487585 0 0 442599 346441 0 515231 133108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 523502 0 317007 0 0 0 0 188846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAPAAKPVAAGSATISAPMPGK MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5703713 7308503 7338217 6149340 6787096 6129564 4982690 8538436 5172738 6646002 7573580 6570334 4140413 5792872 5348378 6158311 6058979 786541 5753852 5336094 5381594 5668657 868718 5259945 5117779 5554442 5434615 699053 6034610 5563906 6439810 7383243 7198068 6325678 7578055 6005760 5243645 5591521 2915629 2541995 3052522 2262579 3758034 4026154 3474528 3746169 2882764 2318494 4073519 3440690 2866970 2530282 2681342 2796942 1770978 1454176 2785765 2782735 2565348 2725139 1536320 0 2747390 2761173 2766445 1115868 2222151 2802609 4280021 2791825 2495480 3289325 4262076 3620147 2689804 2676511 0 0 0 0 0 0 0 254313 0 0 0 0 0 0 0 221603 0 0 111554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPAPAPAPAAPAPAAAPAGAGEVVEAPMPGK MGYG000004158_00688 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister invisus|m__MGYG000004158 1.0 COG0511@1|root,COG0511@2|Bacteria,1VW7S@1239|Firmicutes,4H9EU@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Biotin-requiring enzyme 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 CBM50 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 636039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPNQPK MGYG000002395_00968 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium adolescentis|m__MGYG000002395 1.0 COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Belongs to the transketolase family 1.0 tkt 1.0 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA,Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1042278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2686650 0 2056971 0 0 0 0 0 0 619504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPSGASTGSR MGYG000002506_02347 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,3XNNK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 iPC815.YPO3376 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 67629 0 137194 0 0 0 0 0 0 0 0 0 299707 0 0 0 0 355886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 148507 0 0 0 0 198006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94054 0 0 0 0 0 0 0 800376 0 327977 0 0 0 0 0 0 0 0 0 318649 0 0 0 0 438819 0 0 0 0 0 0 0 0 0 0 0 0 675619 0 0 0 0 594618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPVAAAPA(Ala->Lys) MGYG000004804_00337 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900759415|m__MGYG000004804 1.0 COG0511@1|root,COG0511@2|Bacteria,1VW7S@1239|Firmicutes,4H9EU@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Biotin-requiring enzyme 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 CBM50 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120240 0 0 0 0 115556 0 0 0 0 221301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 981517 0 0 0 0 4806765 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPVAAAPK MGYG000000142_00945 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3074009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPVAAAPVAAAPAAAPK MGYG000003891_01453 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 545447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1298786 0 0 0 0 1849039 0 0 446874 0 961901 0 0 0 0 0 0 0 0 433428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAPVAAGATTVSAPMPGK MGYG000001365_01216 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A|s__Phascolarctobacterium_A succinatutens|m__MGYG000001365 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 85658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191359 0 0 0 0 0 164863 205315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736020 0 1009107 949521 888620 1264989 717318 1507665 864442 647719 848708 875117 910070 0 758556 0 642422 2525608 1050866 814251 0 1000793 2413916 1739021 0 856279 0 1926660 835477 997614 1035424 1381813 1195963 1003194 1524395 0 945283 1067227 -AAAPVAPTADPVIPK MGYG000000212_01006 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3XYZP@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2725912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQAAIANK MGYG000000231_00504;MGYG000000154_00436;MGYG000002517_01243;MGYG000000245_03386;MGYG000001698_00702 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1038590 1181669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1337465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQAAIKNPR MGYG000002274_02693;MGYG000001647_00185;MGYG000004866_01031;MGYG000001300_02837;MGYG000002040_00906 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.8 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQAALNNK MGYG000000193_00368;MGYG000000198_00250 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,268N0@186813|unclassified Clostridiales 0.5 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 982671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQAALTEAISTISK MGYG000000171_02193;MGYG000004733_00324;MGYG000002298_03621 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3Y0DB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 537172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131098 0 0 0 0 526785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1056548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQELAEADRIK MGYG000002970_00028;MGYG000003266_00790 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CUC7@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 O 1.0 SPFH Band 7 PHB domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Band_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQELAEADRIKR MGYG000002970_00028;MGYG000003266_00790 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CUC7@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 O 1.0 SPFH Band 7 PHB domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Band_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQEQLATAK MGYG000002293_00897 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,2FNVT@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 N 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02557 1.0 ko02030,ko02040,map02030,map02040 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02000,ko02035 1.0 1.A.30.1 1.0 - 1.0 - 1.0 OmpA,ZapB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Flagellar assembly 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3134793 0 0 0 0 508998 0 0 0 0 3205290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQGNYDEAIANLSK MGYG000001415_00918 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG0457@1|root,COG0457@2|Bacteria,4PESY@976|Bacteroidetes,2G21B@200643|Bacteroidia,22UIH@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 934494 0 0 0 575814 1028569 1467959 0 0 0 0 0 0 0 0 0 1241916 0 0 969667 0 735977 0 1408778 0 800293 0 0 0 0 0 0 0 0 0 1342122 1057016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492136 0 328334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 474049 0 0 0 0 0 0 0 0 383025 0 0 0 0 0 0 0 0 0 723202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQINLTPR MGYG000000003_00816 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,2FMVP@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG10142 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Porin_2,SH3_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 684040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQIVDTVK MGYG000000018_01784 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus|s__Coprococcus eutactus|m__MGYG000000018 1.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,36JJY@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Involved in the binding of tRNA to the ribosomes 1.0 rpsJ 1.0 - 1.0 - 1.0 ko:K02946 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4675086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQLQQGLAATSDENLK MGYG000002494_04056 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,3XMCB@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Tetratricopeptide repeat-like domain 1.0 yfgM 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_21,TPR_6,TPR_8,Tropomodulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746888 0 704193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQNLD(Cation_Na)GYNEAVAQVMSNNLSAAK MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579484 0 0 0 0 428968 0 0 231100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1848021 0 0 0 0 5007708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309612 0 0 0 0 254545 0 0 2869820 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQNLDGYNEAVAQVM(Oxidation)SNNLSAAK MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348861 241118 237358 447904 289633 882832 450811 0 0 0 0 0 0 0 0 0 299784 0 0 0 0 0 381379 328284 0 0 346066 222434 0 0 0 0 0 445668 422644 425977 0 0 0 279394 0 420496 0 323995 0 0 0 298275 0 0 0 453200 0 303200 0 0 0 0 0 422196 525012 0 0 0 430547 0 0 0 0 0 345818 354025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 344676 0 0 0 0 0 0 0 0 0 0 0 0 0 954175 0 780697 783003 1338734 1056878 806927 785451 1073733 868369 0 0 1070480 0 0 911582 799242 0 1234792 1757690 0 1314726 0 1113773 996021 796917 850548 0 0 989111 818443 0 627313 0 0 786894 1051902 593195 -AAAQNLDGYNEAVAQVMSN(Deamidated)NLSAAK MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 165175 0 0 0 0 0 0 197423 270989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304822 0 0 472280 259281 250279 0 612994 300417 485088 0 387569 0 0 332661 239035 356099 0 444664 445441 0 229941 0 357586 0 315041 0 0 0 396646 0 0 0 0 262687 0 358141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252615 0 0 0 268168 221949 0 0 0 0 0 0 266383 0 0 271683 282353 0 288628 0 0 0 300489 0 0 0 145490 0 0 0 0 0 0 273124 0 747435 0 0 880324 859150 890225 0 622435 695838 797562 0 583499 705634 0 809695 635209 746848 0 1167187 843872 0 405863 0 513950 0 886574 0 0 0 1147965 0 0 0 0 844528 0 806373 0 -AAAQNLDGYNEAVAQVMSNN(Deamidated)LSAAK MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 720584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQNLDGYNEAVAQVMSNNLSAAK MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 374063 339275 294225 0 531731 328467 0 440106 455857 443405 0 0 0 163592 414049 289811 233346 0 0 585535 606146 703430 0 629782 598792 671973 425150 0 344725 211523 166538 0 0 423387 0 1014474 346606 3332224 2217591 1529246 2013344 3713653 2756232 2211294 0 3025279 1909269 3250676 2194051 2525785 0 2878780 3545647 2358923 2179906 0 3155769 3942401 2824692 2135529 0 1512973 2552906 3141981 2467773 0 2281007 2292621 1470932 1802252 1927528 2995417 101072557 1971965 2277515 2209975 0 407520 0 0 127810522 224218 0 372727334 68435381 168903424 134781 0 0 0 185721 19928313 143222705 0 204992 222154 300107 273808 0 121481 71817040 43366441 641282 0 0 221674 0 252954103 0 123687048 29159053 0 75738086 105760497 34538106 1408389 0 24145828 2611242 25817012 0 4621862 3184588 0 71952971 2507187 0 6484574 5058090 25889500 12989370 0 0 2452818 385026458 14432587 0 173930 15517828 4995571 14033966 0 0 4257154 13186702 44146888 27682230 139510634 73658488 8438761 58584681 10113066 63373090 278362234 97867335 329851162 353498549 421777993 0 578828897 96468858 129842163 72760555 48383283 0 243382525 806283547 165133980 706367993 0 179128518 402064850 155622382 509472307 0 83556303 56770748 555458302 412436020 0 29098278 30624548 333389623 108233527 110474981 135483872 319575053 158539398 59653688 53315477 -AAAQPAQVNPC(Carbamidomethyl)IR MGYG000002223_01782;MGYG000001300_01680 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4,Fer4_10,Fer4_4,Fer4_7,Fer4_8,Fer4_9,MTHFR_C,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 724385 799357 1132147 908354 0 562111 379682 434858 554380 601250 649159 378592 0 349703 470762 882167 765933 0 772192 863553 0 959439 0 695451 557299 534800 551873 0 0 0 750099 613580 962743 786597 365367 513565 596354 954668 1605381 1420156 1418495 1714040 1252946 1364953 1888925 869692 1788816 326236 1204626 1509031 0 1674966 1415588 1053956 1727487 0 1931294 1653048 0 1231836 0 1650214 1974568 1546194 1609194 0 0 1320248 1717301 1355356 1644459 1718582 856800 1765824 1481294 1496606 0 244152 0 0 0 0 328616 391449 0 0 177633 0 0 0 0 257997 0 0 0 0 0 470300 0 0 0 248189 0 0 0 0 248686 358325 0 320393 269673 245588 0 0 798648 714916 1345716 816034 950461 1200647 978257 300775 1044324 556531 841506 1052032 0 322127 901023 978303 825737 0 1354033 857406 0 1202027 0 903371 936181 918094 824214 0 0 1039377 1328763 856936 1203671 761735 0 303510 908454 316136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQQELTR MGYG000003291_00352 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_M|m__MGYG000003291 1.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 P 1.0 Belongs to the TelA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TelA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 406405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 811093 0 0 0 0 0 0 0 0 0 0 0 0 936962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2278389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQSGAVGIR MGYG000004271_01794;MGYG000000084_00441 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia 0.5 186801|Clostridia 1.0 G 1.0 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) 1.0 nanE 1.0 - 1.0 5.1.3.9 1.0 ko:K01788 1.0 ko00520,map00520 1.0 - 1.0 R02087 1.0 RC00290 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 NanE,PTS_EIIA_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 N-acylglucosamine-6-phosphate 2-epimerase. N-acetylmannosamine-6-phosphate 2-epimerase. - an N-acyl-D-glucosamine 6-phosphate = an N-acyl-D-mannosamine 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQSTC(Carbamidomethyl)PR MGYG000001636_00982;MGYG000002050_01032;MGYG000003266_01247 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0333@1|root,COG0333@2|Bacteria 1.0 2|Bacteria 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL32 family 1.0 rpmF 1.0 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 1.0 - 1.0 ko:K02911 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L32p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQT(Didehydro)ALLAATSEIDKAC(Carbamidomethyl)TK MGYG000000179_02162;MGYG000000198_04035 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,220RQ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1117445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQTAFGAK MGYG000001658_01879 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01|s__SFFH01 sp900548125|m__MGYG000001658 1.0 COG1053@1|root,COG1053@2|Bacteria,1UK5H@1239|Firmicutes,250H0@186801|Clostridia,26CIB@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1387248 0 0 0 0 538565 0 0 0 0 748056 0 0 0 0 0 484357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286011 0 0 0 0 143750 0 0 0 0 210801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1317094 0 0 0 0 1956839 0 0 0 0 1059018 1500729 0 0 0 0 1819512 0 0 0 0 -AAAQTALLAATSEIDKAC(Carbamidomethyl)TK MGYG000000179_02162;MGYG000000198_04035 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,220RQ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 116066 0 0 0 0 142491 0 0 94407 0 0 0 0 0 0 0 0 0 0 0 0 125566 0 105754 0 106296 0 0 0 0 0 0 0 0 0 0 105369 297003 214112 0 521664 0 0 175447 0 0 220895 0 0 0 0 0 4915304 0 496099 0 0 0 0 110656 0 610413 0 447388 0 0 223849 0 0 0 309206 0 0 0 236243 195186 139759 0 0 0 0 143180 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101446 0 0 0 0 0 0 0 0 0 0 0 218900 0 0 0 0 0 0 0 0 0 0 0 0 0 96060 0 0 0 0 106079 0 241336 0 224524 0 0 0 0 0 0 90871 0 0 0 0 139656 901678 0 359702 0 0 0 0 0 738758 573674 0 0 0 0 671968 0 752283 0 0 0 0 375524 0 387914 0 649089 0 0 1137511 0 0 0 340985 0 0 0 257576 300382 -AAAQTDDMTRPFYPM MGYG000003452_01631;MGYG000002395_00808 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 542429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1200230 0 1573416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQTDDMTRPFYPM(Oxidation)LIFR MGYG000002459_00966;MGYG000003683_00701 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 142019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQTLGLNK MGYG000003683_01120 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4D1EZ@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Ribosomal protein L30p/L7e 1.0 rpmD 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02907 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L30 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2568411 0 0 3571390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1637925 0 4618066 0 0 0 0 0 0 0 0 2359670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAQVPLSVAETAYK MGYG000001367_04132 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q symbiosum|m__MGYG000001367 1.0 COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,24JZM@186801|Clostridia,223XR@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Formiminotransferase-cyclodeaminase 1.0 fchA 1.0 - 1.0 4.3.1.4 1.0 ko:K01746 1.0 ko00670,ko01100,map00670,map01100 1.0 - 1.0 R02302 1.0 RC00688 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTCD_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formimidoyltetrahydrofolate cyclodeaminase. formiminotetrahydrofolate cyclodeaminase. In eukaroytes, occurs as a bifunctional enzyme that also has EC 2.1.2.5 activity. 5-formimidoyltetrahydrofolate + 2 H(+) = (6R)-5,10- methenyltetrahydrofolate + NH4(+). 1.0 1.0 1.0 1.0 One carbon pool by folate;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 423579 0 0 0 0 0 0 0 388934 0 0 0 0 0 0 0 431194 0 0 0 0 0 0 721213 0 0 0 0 0 0 306137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3293055 0 1929659 3727238 0 0 0 0 0 0 4090868 0 0 0 0 0 0 0 2329018 0 2760395 0 0 0 0 3937869 0 0 0 0 0 0 3316477 0 0 -AAARPSAEYHAK MGYG000002517_02750;MGYG000004719_01514 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 L 1.0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site 1.0 mfd 1.0 - 1.0 - 1.0 ko:K03723 1.0 ko03420,map03420 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03400 1.0 - 1.0 - 1.0 - 1.0 CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF,UB2H 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Nucleotide excision repair 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76991 0 0 0 0 0 0 0 0 0 0 0 0 725859 0 0 0 0 0 0 0 0 0 0 0 0 979986 691643 0 693368 0 0 0 0 0 0 0 603967 699245 0 0 0 0 0 0 0 0 0 0 684421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAS(Delta_H(4)C(2)O(-1)S(1)[S](Ser->Met)ESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 736485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1162654 0 656456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 937257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303045 0 583352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 689202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1073361 0 675735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 562691 0 511821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASAEPQR MGYG000002775_00203;MGYG000002947_01254;MGYG000002065_00857;MGYG000000333_00086;MGYG000000188_00614;MGYG000002961_00869;MGYG000001642_00416;MGYG000004681_01110;MGYG000003266_01473;MGYG000001718_00567;MGYG000004746_00769 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CUMW@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682855 189800 0 0 388588 0 0 0 0 0 0 0 0 0 175509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104793 206633 0 0 181981 0 0 0 0 0 0 0 0 0 222168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 509708 514969 0 0 460058 0 0 0 0 0 0 0 0 0 70247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1336277 523542 0 0 433575 0 0 0 0 0 0 0 0 0 606679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASASF(Oxidation[F](Phe->Tyr)GYNEEPIVSSDVIGMR MGYG000004810_01402 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__CAG-272|g__UMGS1815|s__UMGS1815 sp900555345|m__MGYG000004810 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1620557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 526898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 536242 0 0 0 0 0 0 0 0 0 0 0 0 -AAASE(Ammonium)SFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASE(Cation_Ca[II])SFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587419 -AAASE(Cation_Fe[II])SFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 738792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASE(Glu->Gln)SFGYNEDAIVSSDVIGMK MGYG000000179_02084 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1377364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASE(Methyl_2H(3))SFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASEPQSGR MGYG000002494_03460 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,3ZKP2@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Signal transducing histidine kinase, homodimeric domain 1.0 cheA 1.0 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145 1.0 2.7.13.3 1.0 ko:K03407 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt,Response_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 histidine kinase. protein kinase (histidine). This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine).-!-A number of histones can act as acceptor. ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 842189 1081954 538711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 910021 0 0 0 0 1169995 0 0 740557 592116 0 0 0 805353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESF(Oxidation[F](Phe->Tyr)GYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGY(methylol)NEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 529801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYN(Deamidated)EDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1163056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 876996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYN(Deamidated)EDQIVSSDVIGM(Oxidation)R MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYN(Deamidated)EDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1792257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 837161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYN(Deamidated)TDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 863999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392804 0 0 0 0 939721 0 0 0 0 2260517 0 0 0 816681 191586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360843 0 0 0 0 0 0 0 0 0 108302 0 0 265587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385319 0 0 0 0 292808 0 0 0 0 483417 0 0 0 602784 454209 0 0 0 0 371088 0 0 259022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 701122 0 0 0 0 520593 0 0 0 228954 456783 0 0 0 0 276459 0 0 239704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 370074 0 0 0 0 0 -AAASESFGYNE(Ammonium)DQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNE(Cation_Ca[II])DQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 923596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNE(Cation_Na)DPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1485108 0 0 0 0 1555212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1037199 0 0 0 0 0 0 0 0 0 1224896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1358554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNE(Cation_Na)DQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1508815 0 0 0 0 0 0 0 0 0 1457374 0 0 0 0 0 0 0 0 0 0 0 2734858 0 2274646 0 0 0 0 0 0 0 0 0 0 1711095 0 2433962 0 0 0 0 1979741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 988152 0 0 0 0 931979 0 0 0 0 1159346 0 0 0 0 0 0 0 0 0 0 0 0 2581742 0 0 0 0 0 1923649 0 1964746 0 0 0 0 0 0 1076239 0 0 3024648 0 0 0 0 0 0 1421188 0 0 2820693 0 2497154 0 0 0 1805955 2194334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNE(Methyl_2H(3))DQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 576842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNED(Ammonium)QIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 231102 0 0 0 0 0 0 0 0 245776 0 434703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 465645 0 0 0 0 0 0 330906 0 0 0 0 0 0 0 0 423639 0 304713 761021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480654 0 0 0 0 0 0 688573 0 0 0 0 0 0 0 0 0 0 0 1127402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNED(Cation_Ca[II])PIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422900 0 0 0 0 460201 0 0 0 0 403932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 108895 0 0 0 0 217626 0 0 0 0 263709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448859 0 0 0 0 426036 0 0 0 0 293687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 455223 0 0 0 0 814107 0 0 0 0 922613 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNED(Cation_Ca[II])QIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 462761 0 302924 213913 0 280651 156325 0 0 0 238929 219723 297344 333983 0 0 0 0 0 382019 0 250258 0 273924 391517 125209 239994 0 0 108550 346445 0 401601 604301 0 118826 161428 496205 429460 0 628214 539339 0 456716 707599 0 0 0 348625 564053 222824 499885 791603 0 0 0 0 903956 0 312878 0 309056 848015 364219 661467 0 0 641952 690127 698449 557768 566795 0 529844 511814 607399 185470 0 0 0 0 150545 81092 0 0 0 334488 0 82546 79360 79619 0 0 0 0 0 0 0 0 295142 0 138993 160700 0 0 0 0 0 0 146196 0 119524 0 0 562830 0 943200 555496 0 782988 0 0 0 0 650723 724355 1086578 857072 511937 0 0 0 0 709317 0 952073 0 798298 0 703723 780706 0 0 761123 871261 660052 765788 892564 0 535284 594017 0 0 0 271614 161982 0 0 556130 0 0 0 0 0 0 550140 644769 0 0 0 0 0 0 0 0 0 446727 0 554881 0 0 0 637915 535523 722871 532226 0 429597 0 142115 -AAASESFGYNED(Cation_Fe[II])QIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 918471 0 0 136643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161286 0 164502 0 0 0 0 0 0 0 0 0 235986 0 0 0 0 0 0 641842 0 0 454889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310050 0 470096 0 0 0 0 0 0 0 0 162793 521877 0 0 0 427597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 714408 0 0 786551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 834757 0 864323 0 0 0 0 0 0 0 0 0 612158 0 0 0 649951 0 0 511278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298400 0 0 0 0 0 0 0 0 0 0 402349 243711 0 0 0 583438 -AAASESFGYNED(Cation_Na)PIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 190885 0 0 0 0 307592 0 0 0 0 0 0 0 0 0 393567 0 0 0 0 0 0 0 0 0 0 0 0 0 289021 0 0 0 0 0 0 0 1619961 289368 0 0 0 0 1387503 0 0 0 0 0 0 0 0 0 0 0 1247387 0 0 0 0 0 0 0 0 0 0 0 396143 0 0 0 0 0 0 0 1045751 468801 0 0 0 0 783509 0 0 0 0 888937 0 0 0 0 853887 0 761585 0 0 0 0 0 0 0 0 0 0 0 605352 0 0 0 0 0 0 0 707003 813179 0 0 0 0 0 0 0 0 0 1130190 0 0 0 0 0 0 750190 0 0 0 0 0 0 0 0 0 0 0 441941 0 0 0 0 0 0 0 0 307963 0 0 0 0 1893361 0 0 0 0 2027283 0 0 0 0 2411531 0 771119 0 0 0 0 0 0 0 0 -AAASESFGYNED(Cation_Na)QIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1226962 1094675 1897071 1218810 212599 905393 943994 586800 1112082 930906 0 921218 1253189 1095191 596708 717775 1095480 682721 1507563 1227562 477244 597557 680873 802135 778936 773288 837981 948799 0 529149 1402857 896863 0 1443888 0 1007184 1091883 1429249 1755077 1729392 2208148 1964362 0 2099991 2895943 943190 1729285 581171 0 2185790 1814735 1954658 2570919 1931181 0 1422002 0 2909238 1251944 1701503 1482603 2307986 2775580 2088722 2180761 1322552 0 0 2191095 0 1836684 2018086 0 1826316 0 1880812 457912 369849 419225 485264 414532 415761 380836 0 365085 246330 0 401454 249901 280816 410136 264428 343316 924597 279514 416907 330000 317695 896156 513946 412740 509529 406049 760795 0 426681 357137 477786 329425 427617 0 306335 174643 436325 1439643 1827436 0 1653181 1823558 2331827 2883469 792867 0 1470196 0 2561120 2933421 2086031 1533068 1990964 2031833 0 2406534 2010255 0 2657373 1488254 2393913 2567040 1881093 1904345 1386765 0 1936950 0 1964801 0 2344758 0 1686358 0 0 444763 461086 728902 255274 424630 248176 206156 422511 749584 707295 0 357039 213263 318290 700556 441360 628430 1603259 183445 216861 384870 542729 350542 395522 612442 830713 680651 1255833 0 918184 440085 286193 755599 646630 0 619503 986382 1025152 -AAASESFGYNED(Methyl_2H(3))QIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 288662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 643024 0 474574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNEDAIVSSDVIGMK MGYG000000179_02084 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 322934 0 231162 247256 0 0 386385 0 376332 218120 337747 0 0 312862 109495 0 255142 0 0 0 244281 307757 0 0 219131 391404 171720 0 462517 388128 0 0 717956 190123 0 0 362747 162986 0 0 306994 317436 0 0 0 0 322592 0 331328 0 0 289367 0 0 0 0 0 425898 193212 545396 0 208065 0 0 280773 0 0 362312 0 0 0 304488 0 217556 0 232303 425915 0 163323 0 0 0 207384 0 98037 0 138913 0 0 180911 236139 0 0 0 0 263599 0 0 0 0 0 431925 0 0 463058 0 0 0 0 0 0 192621 0 0 286523 0 298877 544474 0 341728 156955 0 747955 248218 86918 0 0 746057 300407 0 315331 0 0 407874 425542 0 0 0 398738 0 259173 0 245675 191165 0 0 319994 170805 0 364866 272257 0 3254936 0 1184003 1957933 0 750891 1514889 0 2192657 2122244 1216619 0 0 2985195 2321025 0 1771321 0 1978511 2906171 1731926 1770596 0 1549331 1803795 2946690 2477738 0 3201244 1797254 0 0 1511655 2907456 0 2782549 3651375 1703499 -AAASESFGYNEDAIVSSDVIGMR MGYG000001311_02933 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000155435|m__MGYG000001311 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 799463 0 0 0 0 0 0 0 704029 0 0 0 0 0 0 0 0 0 0 0 0 675342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189435 0 0 0 0 0 0 0 355768 0 0 0 0 0 0 0 0 0 0 0 0 254338 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153743 0 0 0 0 0 0 0 131861 0 0 0 0 0 0 0 0 0 0 0 0 336688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402170 0 0 0 0 0 0 0 255505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534658 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNEDL(Xle->Gln)IVSSDVIGMR MGYG000001255_00370 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_F|m__MGYG000001255 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1656053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNEDP(Pro->Gln)IVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 2673808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 983409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNEDPIVSSDVIGM(Oxidation)R MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 980692 0 0 0 0 0 821586 0 0 0 0 653960 0 0 0 0 613786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 988294 0 0 0 0 0 929010 0 0 0 0 1101139 0 0 0 0 729904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609747 0 0 0 0 0 711767 0 0 0 0 956302 0 0 0 0 1691034 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1188520 0 0 0 0 0 1083257 0 0 0 0 1114323 0 0 0 0 1549262 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNEDPIVSSDVIGMK MGYG000003510_00403 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__UBA6857|s__|m__MGYG000003510 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641277 0 0 0 0 0 0 404253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 603273 452539 498636 0 0 533683 0 903044 227628 0 203127 0 398740 0 411048 444886 609129 482912 0 0 0 425135 905074 249835 0 0 0 789335 0 0 686431 0 391637 0 0 214546 560039 231357 866057 638511 809653 1071513 727104 650551 943036 1105159 746380 958009 769278 6002596 867346 1019367 1003118 634503 828590 4871421 726601 987559 904003 786369 5454693 0 893449 1106009 0 5197341 1040895 4041175 1100366 419117 770297 849379 936038 946552 910171 690796 1370600 1602976 1339954 1134852 851388 1126665 1359665 1766557 1472481 1628967 1267132 3142538 1789098 1467217 1988464 1323445 1496045 2414873 1531668 1560293 1556414 1335532 2290851 875153 1350611 1634822 1657218 3187826 1401826 2808620 1006009 1173613 1365993 1949527 1952554 1449589 1812739 1695683 1972943 1678371 1586476 1912548 2107705 2129950 1573005 1759738 1752197 1837661 1846385 2461887 2169236 1564738 1357541 2144622 2010716 3297307 1346833 1742728 1537158 2347855 3113957 2306538 2097245 1453970 2036016 4518272 2373270 2449672 2065717 1329828 1539759 835205 1209029 1404706 1215859 1878783 1386468 1824362 1630936 1398852 1094356 1070325 1460741 1703970 1148574 1054657 1621671 4971665 1420068 2215776 1277563 1263231 1189301 5746827 998911 1073390 1829984 1250764 6811836 1518200 1909771 1463965 1777320 7202305 2206664 2553994 1938969 1667068 2216586 1562104 1854380 2127314 1490630 1567348 -AAASESFGYNEDQIVSSDVIGM(Oxidation)R MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 666624 844872 1069777 918282 0 618630 609528 0 514144 318303 900291 521983 695183 511855 723065 959293 1443038 1103023 979619 728523 318954 1478075 470709 765705 726543 1051861 364642 482156 0 211636 795543 591499 1074792 861300 0 745910 518205 883954 867573 1043824 974174 1630904 1184023 1466375 2010093 0 3028262 357695 1174653 1826928 284736 0 1450873 1250188 1461273 1683660 1501753 1205037 723525 759537 1101860 1633722 1568271 1019459 1140101 910171 0 1159004 2087483 1343059 1031949 1140878 0 1221705 1444878 1872507 587332 597506 359968 604461 479735 495957 500818 0 417396 448012 607346 389868 383663 464716 438246 523850 464194 1272602 232616 346315 365048 321812 1200462 261749 338080 494640 417871 1287838 0 392995 361838 381103 307178 323240 0 300468 325726 512920 1473247 1566775 2323435 1491214 1336438 1715923 1822512 0 1333636 1103224 1689047 2381848 2557015 1712587 1394156 1358547 1556865 1081162 2193289 1747797 1730642 1879698 1586967 1925232 1253333 1393929 1103293 1293907 0 1892415 2106916 0 1886916 1808502 0 1274122 1717084 1881644 317692 329384 314369 1367245 0 149284 182455 0 1911569 923508 163071 1297622 1053632 1224789 190065 1500998 447244 270359 272442 351703 1472352 0 304865 285253 197942 179440 194787 313804 0 915460 188771 834812 451099 1733956 0 872568 313364 303704 -AAASESFGYNEDQIVSSDVIGMK(Lys->Arg) MGYG000004087_02290;MGYG000003431_01105 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2311483 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3733746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402207 0 0 0 0 566725 0 0 0 0 545056 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 3696553 4502717 7428028 6024758 492492 3440633 3782790 2239322 4286968 3320297 3826809 0 4565398 4218696 2335908 3502254 4096399 0 6930280 3860357 1487416 2963776 2917439 3358721 3526261 3757754 3520132 3432443 1165323 0 5459414 2866620 5632270 6798639 1970225 3378705 3562177 5262245 7718420 6174612 8832362 9010803 6062558 10457755 0 4026947 6909045 1696823 0 10586856 7286481 8287354 11583192 7272654 11155792 5487603 10989296 15451344 5080823 8577483 0 9432662 12107354 8347263 8754037 0 0 6515289 9444611 11106114 6210661 6553758 2464669 6245733 7278113 8091513 1301979 0 698582 0 1118227 991734 1883799 914749 0 753280 0 0 1121291 0 1161559 1373598 801270 3269347 1028995 1377878 1044428 859820 3203316 1008699 1343201 1586550 0 0 586276 1095032 0 1819524 737595 1300617 898479 1351436 1146178 643068 5192124 6706602 10356606 7978650 6604844 8412571 10157402 2720436 6184666 5265362 6606838 8815837 9853604 9053380 5078261 8576267 7073355 3558511 9661767 9552363 7914630 9816255 4369787 7632982 8208870 7007172 6765479 4472111 2702696 7786448 10189819 10065239 9167360 11060590 0 5652726 6238409 7932428 359089 322066 201689 288014 596487 227543 256768 176261 390303 298157 223451 224853 294417 336825 208303 329092 542691 578649 233711 256488 239821 381365 707068 659070 331149 257618 201613 730051 409378 441014 276092 466414 322837 271063 759773 156035 247869 457822 -AAASESFGYNT(Formyl[T](Thr->Glu)DPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 840379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 935580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 1733013 1749701 1681142 1778430 0 1868811 1558526 1785705 2609155 0 1875900 1338916 1194332 1566555 1742558 3845741 1029215 1251730 1173798 1620580 3091149 1073914 1445697 0 0 4459969 0 0 1651659 1621357 1189924 0 1345676 0 0 1338674 0 0 0 238176 0 0 0 0 0 0 356487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326669 0 0 0 0 0 0 0 0 0 0 0 0 317837 524309 0 0 0 0 0 413248 255387 0 164879 552691 546738 592649 0 351056 451533 487079 0 433862 387602 364370 459914 0 0 718505 0 0 300448 360293 499629 0 360290 0 0 312719 0 0 739363 608194 557940 767804 0 782505 723900 543865 711456 0 656986 514353 834814 432931 578175 1241159 425503 560599 455077 538293 818305 516961 755907 0 0 2364166 0 0 769694 593591 389632 0 337265 0 0 447692 0 0 666102 564537 282186 388808 0 400583 487637 560509 1465251 0 759967 840062 667830 461172 276155 379399 525403 382739 491350 446246 859596 555671 591369 0 0 935316 0 0 860947 664127 676772 0 863208 0 0 665224 -AAASESYGYNEDPIVSSDVIGMK(Lys->Arg) MGYG000002946_02881 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp900555905|m__MGYG000002946 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASESYGYNEEQIVSSDIVGM(Oxidation)R MGYG000003552_01242 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-127|s__CAG-127 sp900539705|m__MGYG000003552 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASLGALGFK MGYG000004797_00778;MGYG000002478_01127 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 1165977 0 987513 0 0 599888 0 536986 0 0 0 958711 0 1125545 0 0 866201 0 0 0 0 0 0 0 0 0 0 0 0 0 1067478 0 0 0 0 986540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 235253 0 0 0 0 0 0 0 0 0 0 94339 0 184516 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252572 0 0 0 0 182941 0 0 126519 0 0 0 0 130094 0 229154 0 0 0 111267 0 0 0 0 187639 0 0 0 0 0 0 0 0 0 0 0 0 0 73580 0 0 0 0 300019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASLGEMGFR MGYG000000029_02049;MGYG000000236_03409;MGYG000001345_04416;MGYG000004876_01120;MGYG000003681_02554;MGYG000003363_00071;MGYG000001346_01988;MGYG000000196_02827 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 301471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1125149 0 0 0 0 0 0 0 0 0 0 0 0 563876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASLPDIR MGYG000002478_00527 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1435@1|root,COG1435@2|Bacteria,4NFWU@976|Bacteroidetes,2FNY3@200643|Bacteroidia,4APFH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2146439 1684424 1187356 1967090 1839862 1927532 1879587 0 1854923 0 0 0 0 2007741 0 2160120 1848473 0 1827204 0 2189367 2026515 0 2588260 1658367 2126812 1910868 0 2146543 1944021 0 2164646 1457128 0 2100614 0 1935628 1396073 947383 755646 1066138 1013860 567295 996975 735378 0 1196788 0 0 0 0 1165928 0 965114 686163 0 974925 0 814115 823805 0 788780 1084706 992317 801252 0 898623 634073 0 697877 1376678 0 973793 0 971218 876549 956477 580142 747265 982720 1073172 942551 953804 0 1002613 0 0 0 0 842457 0 737205 870618 0 1065600 0 678655 538165 0 824550 793414 717496 862309 0 908713 659580 0 560983 769978 0 610633 0 801956 784574 161257 0 0 180174 0 247284 136202 0 117510 0 0 0 0 141740 0 155927 0 0 321368 0 404188 0 0 0 145597 300442 0 0 220324 171577 0 278167 202394 0 285650 0 155533 135010 838527 717011 632442 710225 1297231 1097305 968613 0 1220170 0 0 0 0 438678 0 1169139 768133 0 983824 0 563031 949929 0 859617 713091 520706 575946 0 602176 1297262 0 563957 442166 0 828609 0 835502 778802 -AAASQEMTLVDTPNAK MGYG000002494_03091 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS 1.0 proS 1.0 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.15 1.0 ko:K01881 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03661 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iUTI89_1310.UTI89_C0210 1.0 HGTP_anticodon,tRNA-synt_2b,tRNA_edit 1.0 - 1.0 - 1.0 - 1.0 CBM50+GH25 1.0 proline--tRNA ligase. prolyl-tRNA synthetase. - ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 286964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169328 0 0 333276 0 354788 776280 0 836975 0 643962 965663 0 558937 0 834829 0 523098 0 0 0 0 0 0 0 0 0 1264675 0 980348 713001 601480 0 0 0 0 0 0 953071 0 0 590390 566308 690619 0 0 0 0 0 0 0 0 0 137212 0 295183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245339 0 298223 451065 0 323884 0 266854 0 0 186812 0 252324 0 0 0 0 0 0 0 0 0 0 0 167457 0 471878 281266 252435 0 0 0 0 0 0 294803 0 0 162221 0 370056 -AAASQSFGYNEDPIVSSDVIGM(Oxidation)K MGYG000003937_01177 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1167846 0 0 0 0 568376 0 0 0 0 765948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASQSFGYNEDPIVSSDVIGMK MGYG000003937_01177 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1899388 2061579 2342298 1807186 1872489 1953133 1546716 2763143 2063933 2954897 2740430 2626570 2664147 1831230 1851179 2506245 1971429 3823268 2336666 1951527 1911422 1785558 2505716 1171544 2150712 1750064 1866015 3694295 2798570 2204370 1358622 1475302 1312477 1758362 1717153 1689334 2026221 1546192 0 213158 0 0 0 0 292407 0 0 0 0 0 0 223296 0 0 0 462469 165101 162706 0 0 305584 0 0 0 0 456288 203164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292457 244541 0 323959 355523 0 259311 0 235282 0 243121 122288 277821 0 0 252459 237156 244441 241709 276470 0 0 353447 204704 337648 0 0 288286 400833 295984 0 243321 0 522352 571053 383498 485947 786710 530315 463599 425378 486339 532287 563636 667521 626859 511820 388807 651321 691366 670959 280247 440939 310950 699440 359287 445578 460332 354610 585049 997709 437968 521980 629514 283650 479868 364609 408460 385805 400123 364079 838147 547565 520171 0 683147 336902 204166 609854 950194 206273 548024 746090 0 868831 937754 189328 1084692 180227 510621 0 884021 722498 242068 374769 500603 502311 368397 312577 0 498378 788534 0 562757 762405 486011 906708 835713 905070 -AAASSAAPAEDVTIK MGYG000003166_01579 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539885|m__MGYG000003166 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 988017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASSFNK MGYG000000198_05930 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Cell wall-binding repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 92493 0 723679 413207 621080 187545 532280 210960 500604 172388 1099304 352614 1367781 66538 432093 758328 202484 0 178845 171601 267689 85024 0 273235 289727 292429 388708 0 253837 272310 0 203972 1381755 270387 0 329735 303874 1087348 163079 0 165126 136261 573010 429966 178425 163125 200587 264291 1366220 142480 1638987 197558 192899 741492 191201 0 254738 163420 309854 215939 0 487188 294167 166054 86364 0 401383 267494 0 302734 186445 158798 0 163327 138715 199641 4750057 0 4484537 5251455 3395817 2081346 2943706 3389098 5491576 1510508 3507163 4240238 4821611 5776110 6531190 4067992 1943736 0 5319960 6432734 6586443 3533686 0 4060824 2243397 5186218 7812961 0 8529902 2185307 0 2007862 3375658 5156814 0 7287413 5887150 4040334 218465 0 251836 241195 97653 211534 97406 160456 296677 176115 756731 0 180049 249961 166227 223336 145603 0 198658 230400 93072 278895 0 175472 104226 300716 80617 0 175693 196538 0 131146 0 0 0 111108 189221 180484 194381 0 164839 395646 445046 239665 175050 241056 412132 0 972718 297206 1665761 447526 128953 592313 243049 0 208566 175095 0 196906 0 771991 379071 433797 366521 0 0 293576 0 0 0 308471 0 282202 0 267278 -AAASSLGM(Oxidation)AEKVAK MGYG000000196_04005 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia,4AQZ3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2020404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASSLGMEAMPK MGYG000002478_00783 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia,4AQZ3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1198583 0 0 0 0 362812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASSPALTAVVAQSEYANLQR MGYG000003937_01616 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG2182@1|root,COG2182@2|Bacteria,1VRPK@1239|Firmicutes,24Y63@186801|Clostridia,3WJGG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 836195 0 0 0 0 876942 0 0 0 0 772412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 840057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAASYLDLPLYR MGYG000002549_00850;MGYG000000196_01187 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 221336 0 0 0 0 0 0 0 264536 0 0 0 0 92639 0 279585 0 0 0 250080 93315 0 0 223068 0 0 0 383208 281940 0 0 0 245748 0 0 311453 152440 1092039 1126944 1369783 0 0 1347291 1317234 0 1171842 1556931 0 0 0 1591364 1884883 0 1247868 0 0 1392581 1509922 1312684 0 1112100 1449828 1625209 0 0 1242369 1536998 0 0 1146910 1421998 0 0 1569179 1289166 303083 0 245012 0 0 126561 327101 0 261207 204133 0 0 0 271803 119672 0 329081 0 0 214046 265623 0 0 99778 231484 238197 0 0 294130 194625 0 0 252825 471545 0 0 317201 280325 423794 356556 257521 0 0 237818 406633 0 373981 277851 0 0 0 359360 455127 0 262879 0 0 345127 428705 445962 0 214542 460113 567343 0 0 468499 322067 0 0 198590 227488 0 0 492401 170200 834382 609444 166652 0 0 946210 920745 0 964107 580550 0 0 0 894252 571245 0 935748 0 0 983795 858104 617379 0 870821 1167188 1058032 0 0 1197581 955059 0 0 808026 886047 0 0 1087438 678373 -AAATAADKAR MGYG000004733_00775;MGYG000001338_01157;MGYG000000133_00993;MGYG000000301_01128 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7586 0 0 0 0 0 0 0 0 12795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102333 0 0 0 0 0 0 622159 0 0 0 0 0 0 116135 0 829475 0 0 0 0 0 0 0 0 27989 0 0 0 0 0 0 0 0 0 0 33527 0 -AAATAADKM(Oxidation)R MGYG000000315_00696;MGYG000000031_00643;MGYG000000142_00071 domain d__Bacteria 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 0.6666666666666666 186801|Clostridia 0.6666666666666666 C 1.0 Psort location Cytoplasmic, score 9.98 0.6666666666666666 adhE 0.6666666666666666 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAATAADKMR MGYG000000315_00696;MGYG000000031_00643;MGYG000000142_00071 domain d__Bacteria 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 0.6666666666666666 186801|Clostridia 0.6666666666666666 C 1.0 Psort location Cytoplasmic, score 9.98 0.6666666666666666 adhE 0.6666666666666666 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 142847 266679 725891 140081 609608 0 54717 804689 0 0 1668594 0 575033 0 793280 0 530015 0 0 0 0 0 0 0 0 267716 429850 0 304587 0 337993 0 0 448912 426734 77098 101573 540230 804334 1267555 725560 400519 2063647 0 1423402 1084211 0 0 1858493 0 722173 0 745609 0 653775 0 0 0 0 0 0 0 0 907157 1362205 0 1060547 0 2042047 0 579871 1135863 711311 831436 547244 477898 47618 154090 182964 43474 33800 0 37463 64178 0 0 91399 0 152203 0 55366 0 43187 0 0 0 0 0 0 0 0 51809 139321 0 114594 0 73965 0 367136 177946 146179 0 41234 133018 42440 52161 44954 0 261867 0 257316 0 0 0 102612 0 115986 0 0 0 289394 0 0 0 0 0 0 0 0 0 245228 0 177881 0 0 0 180186 96133 0 0 126415 71714 138453 252948 346785 63240 49583 0 162315 145022 0 0 305889 0 182190 0 82822 0 120219 0 0 0 0 0 0 0 0 134224 81024 0 140781 0 276993 0 424808 147515 89508 255829 206135 153986 -AAATAANQM(Oxidation)RIPLAK MGYG000001754_00010 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-110|s__CAG-110 sp900752285|m__MGYG000001754 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 3219964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3275736 0 3188817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1041952 0 632209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAATEATPAAETAAPVAEAPAAEEAKAE MGYG000001346_01491 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,2FNPH@200643|Bacteroidia,4AK8D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal protein L17 1.0 rplQ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02879 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Ribosomal_L17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 360562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310011 1239358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 901067 226023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2662709 555968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAATESFGYN(Deamidated)EELIVSSDIVGMR MGYG000000562_01218 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp000437735|m__MGYG000000562 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,25VFF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269587 0 0 0 0 180048 0 0 0 0 421824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410657 0 0 0 0 448926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAATESFGYNEDEIVSSDIVGMR MGYG000002304_00547;MGYG000004735_01946 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27V6G@189330|Dorea 0.5 186801|Clostridia 1.0 C 0.5 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 764530 0 0 0 0 0 1051826 1818087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2898386 0 0 0 0 0 2011549 1777339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525037 635626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1605007 231174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25411828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAATESFGYNEDEIVSSDVIGMR MGYG000004493_00097 genome d__Bacteria|p__Spirochaetota|c__Spirochaetia|o__Treponematales|f__Treponemataceae|g__Treponema_D|s__|m__MGYG000004493 1.0 COG0057@1|root,COG0057@2|Bacteria,2J5AD@203691|Spirochaetes 1.0 203691|Spirochaetes 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAATESFGYNTDEIVSSDIVGMK MGYG000001607_01815 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_B|s__Dorea_B phocaeensis|m__MGYG000001607 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 501713 0 0 0 0 579870 0 0 0 0 872704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAATLMK MGYG000000243_01167 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,4ANQH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3096234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1111058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 768834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397892 0 0 0 0 0 0 0 -AAATQEMTLVDTPNAK MGYG000003372_01055;MGYG000002506_04331;MGYG000003365.1_03562;MGYG000000093_03470 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS 1.0 proS 1.0 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.15 1.0 ko:K01881 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03661 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iUTI89_1310.UTI89_C0210 1.0 HGTP_anticodon,tRNA-synt_2b,tRNA_edit 1.0 - 1.0 - 1.0 - 1.0 CBM50+GH25 1.0 proline--tRNA ligase. prolyl-tRNA synthetase. - ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 536441 0 0 0 372345 0 0 0 0 0 0 0 0 0 0 0 410056 0 347414 0 0 444823 0 0 0 0 0 0 0 384919 0 403703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1201562 0 0 0 542351 0 0 0 0 0 0 0 0 0 0 0 674835 0 1006390 0 0 0 0 0 0 0 0 0 0 0 0 434773 0 697824 0 0 0 0 854490 0 0 0 602905 0 0 0 0 0 0 0 0 0 0 0 917337 0 0 0 638607 861658 0 0 0 0 0 0 0 933494 0 311320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAATTPAGDGIQLSGNEVNITLKPGATPAVDPK MGYG000000243_02343 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 2DUE9@1|root,33Q7G@2|Bacteria,4P1S2@976|Bacteroidetes,2FQRY@200643|Bacteroidia,4APG5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Domain of unknown function (DUF5115) 1.0 - 1.0 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0005982,GO:0006073,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030246,GO:0030247,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044462,GO:0044464,GO:0071704,GO:0071944,GO:2001070 1.0 - 1.0 ko:K21571 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF5115,SusF_SusE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 987370 1109964 1088290 1460842 1658939 987493 0 1216167 1194968 883046 0 0 0 0 799903 0 1285592 1061060 869272 795988 0 788056 1562992 918521 865514 1195290 1239258 1238649 0 1107521 1207557 1849571 1197688 1254995 0 1187634 850712 963085 0 0 0 0 356178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388616 0 0 0 0 0 0 0 0 218263 0 0 0 0 0 0 582836 464438 620283 399223 1267966 553450 0 525935 625954 475402 0 0 0 0 394580 0 366605 2183574 786971 251385 0 428784 1943218 561871 250523 496178 534530 1489635 0 398552 615350 574835 518647 382531 0 649422 464956 547129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVAAAK MGYG000001300_00438 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3WG9R@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 aconitate hydratase 1.0 acnA 1.0 - 1.0 4.2.1.3 1.0 ko:K01681 1.0 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 1.0 M00009,M00010,M00012,M00173,M00740 1.0 R01324,R01325,R01900 1.0 RC00497,RC00498,RC00618 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aconitase,Aconitase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aconitate hydratase. citrate hydro-lyase. Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate.-!-The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate.-!-cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate.-!-Formerly EC 4.2.1.4. citrate = D-threo-isocitrate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Citrate cycle (TCA cycle);Glyoxylate and dicarboxylate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1447459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVAKEVEK MGYG000000271_02014 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVAKEVEKK MGYG000000271_02014 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVAVAAGPAAGAAAAEEK MGYG000001345_04691;MGYG000004797_04276;MGYG000002478_00807;MGYG000000236_01800 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518984 0 0 0 0 649021 0 291949 0 0 0 0 622615 0 0 0 0 532272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 946379 0 0 0 0 680994 0 0 0 0 717609 0 0 0 0 0 0 0 0 0 0 -AAAVAVAAGPAAGGAAAAEEK MGYG000003697_01479;MGYG000002293_00514 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635871 0 0 0 0 254764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577755 0 0 0 0 0 0 0 0 0 356189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1294683 0 0 0 490771 2040322 292588 0 0 0 517702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378321 0 0 0 0 193246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVAVAGPAGAGAAAAEEK MGYG000004780_01209 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Neisseriaceae|g__Neisseria|s__Neisseria sp000186165|m__MGYG000004780 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,2KR8H@206351|Neisseriales 1.0 206351|Neisseriales 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 711871 0 0 0 0 0 0 0 0 -AAAVDAR MGYG000000196_04766 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG3087@1|root,COG3087@2|Bacteria,4NU0A@976|Bacteroidetes,2FPJ1@200643|Bacteroidia,4AKB9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 D 1.0 Sporulation and cell division repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SPOR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 562069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVEAHDIDPNAK MGYG000002098_02080;MGYG000001658_01879 genus d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01 1.0 COG1053@1|root,COG1053@2|Bacteria,1UK5H@1239|Firmicutes,250H0@186801|Clostridia,26CIB@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1180947 0 234265 0 0 638715 0 251509 0 0 0 0 0 595937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489302 0 2069163 0 0 970386 0 984379 0 0 0 0 1798763 2108032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1604700 0 1188668 0 0 1682174 0 2020192 0 0 0 0 2414761 1603787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3604661 0 754608 0 0 5171285 0 1555699 0 0 0 0 2204588 5183887 0 0 0 0 0 0 0 0 0 -AAAVEAPK MGYG000003122_01008 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900541235|m__MGYG000003122 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,2GJU4@201174|Actinobacteria,4CUBT@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 TIGRFAM PTS system, fructose subfamily, IIC 1.0 - 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS_EIIA_2,PTS_EIIC,PTS_IIB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS);Metabolic pathways;Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 698171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1147553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1266436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVEASKN(Deamidated)GAEK MGYG000002528_01429 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DAO,FAD_binding_2,FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVEQLQVWGQR MGYG000002535_04546;MGYG000002506_03085;MGYG000002494_02119 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,3WWK2@544|Citrobacter 0.3333333333333333 1236|Gammaproteobacteria 1.0 D 0.6666666666666666 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components 1.0 ftsY 1.0 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 - 1.0 ko:K03110 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 COX15-CtaA,SRP54,SRP54_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 717101 0 409945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 349557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVGLK MGYG000003022_00736;MGYG000004642_00845;MGYG000000187_02028 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,1KJ5X@119065|unclassified Burkholderiales 0.3333333333333333 186801|Clostridia 0.6666666666666666 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3332341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVIDK MGYG000001300_00243 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1121836 0 0 275011 0 0 0 0 0 0 13716986 0 0 0 0 0 0 0 0 1393270 1125634 483335 0 0 0 0 0 0 0 0 0 0 0 0 0 622937 0 0 531534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11526450 0 15639591 8694036 0 0 0 0 0 0 14145406 0 0 0 0 0 0 0 0 15619664 0 17180558 0 0 0 9699647 0 14985083 12095320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVLDK MGYG000001300_00243 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 9565049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16083675 13196231 0 0 0 0 20570030 0 0 0 10070606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13536473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVLLQR MGYG000001315_02695 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0607@1|root,COG0607@2|Bacteria,1V09Z@1239|Firmicutes,24AZV@186801|Clostridia,21ZFU@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 P 1.0 Rhodanese Homology Domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rhodanese 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1039279 0 1592213 421962 1049596 709782 0 0 0 859882 1166162 1014172 0 0 0 777879 0 0 746402 908337 0 769203 0 941188 0 833209 596730 0 0 0 0 872514 1773736 0 846288 0 642766 1748631 2063089 0 4042782 1913121 2436600 1874639 0 0 0 2485081 2383348 2004951 0 0 0 2640244 0 0 2079142 1702186 0 0 0 1550119 0 1658487 2268608 0 0 0 0 3729638 5188509 0 2637418 0 1815774 3705560 527645 0 120063 0 299655 394252 0 0 0 367654 169169 292656 0 0 0 0 0 0 0 0 0 101030 0 253774 0 267744 681369 0 0 0 0 0 163350 0 0 0 317902 97660 101269 0 363831 0 0 0 0 0 0 0 0 416944 0 0 0 0 0 0 0 449688 0 0 0 126564 0 387526 438064 0 0 0 0 0 0 0 0 0 383434 0 1335240 0 2518144 1504560 2221180 991307 0 0 0 1095201 480838 1050693 0 0 0 866599 0 0 1288627 1975421 0 1383575 0 972482 0 1603336 866266 0 0 0 0 513768 1567245 0 1521133 0 1237383 3001731 -AAAVMEALR MGYG000001617_00231 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp900547735|m__MGYG000001617 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,21Y1Y@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVN(Deamidated)IVPNSTGAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 265213 0 0 0 214313 0 0 0 0 0 0 0 0 0 0 1131309 0 205872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 509012 0 860197 0 0 0 907635 710554 0 298729 0 0 0 218113 0 0 0 128814 0 0 338602 0 388997 0 0 167732 393710 0 0 0 246572 0 0 319034 0 158769 0 0 0 0 2100470 0 0 1940119 1504377 0 0 1445399 0 1821617 0 1401178 0 1162859 1400923 1461837 0 0 0 0 1512047 0 1559972 1479660 2526548 0 0 0 0 1893032 0 1691930 0 0 0 0 1705681 0 1006256 0 0 664186 0 0 0 0 0 912432 0 570135 0 1419646 0 233731 0 0 0 0 884715 0 0 0 0 0 0 0 1280454 533783 0 844110 0 1074897 0 0 630307 0 0 0 0 188415 375113 700111 0 0 0 412106 0 346844 0 0 444529 430869 0 0 924567 0 254018 0 215119 0 177102 0 0 0 806140 174261 0 383620 0 166166 -AAAVNEYTVTFHPVSALDQTPIADAK MGYG000004735_01160 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1520@1|root,COG1520@2|Bacteria,1VR6X@1239|Firmicutes 1.0 1239|Firmicutes 1.0 M 1.0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1005307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVNIVPN(Deamidated)STGAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 4078392 6494103 4130174 2941421 4627514 4546156 1853335 4790340 2406983 4953301 5067609 5290860 5944851 2702386 4532735 5695671 3368524 3087178 2756037 4819058 4704526 5627341 3045597 1625522 4939410 3072599 3543349 3033173 3352033 3794551 1252360 4480922 2745705 3107595 3299389 2279243 2609165 2908405 3297976 8795952 2537084 3082174 5021266 2816801 3954987 4393953 2983473 2524910 2947581 2797499 4172785 2271061 2251700 2022005 2619719 8662830 2521672 4088645 3287676 0 4651588 5506503 3127478 3013912 3906796 8083229 8002829 4745251 9237914 5101627 2923419 4356597 4241853 4004354 3811857 4408173 5078054 15976974 0 0 1387117 0 0 6136795 1876988 5598511 0 3861888 5263294 3996672 5488889 6590224 4715706 3099238 6585206 5742472 4739264 10937806 5526549 0 5094462 4377391 6923467 8254211 6346048 7213073 0 14610713 9243121 7893804 6973471 2160102 3393553 0 3156571 2584678 1396194 2277051 2250507 1008515 0 3061216 2193158 1167429 1535684 0 1969757 2976046 2761394 0 0 0 1521449 2042792 2376568 765194 0 616059 3004826 2505403 2764315 218532 0 2321630 0 3082115 1654505 1944409 2889703 2109856 3459695 0 8591826 12290223 18605059 8067591 3646916 8700802 15793812 8108862 9135244 15639228 11087124 14210846 3773821 16523885 13529719 9037757 12810145 1808461 11745509 3864791 13200929 7187278 2730532 7441138 12395535 9229354 12281103 3369326 11561920 5384874 10404292 8928709 19031053 12745210 7353617 11321856 12117215 11464127 -AAAVNIVPNS(Formyl[S](Ser->Asp)TGAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVNIVPNS(cGMP+RMP-loss)TAK MGYG000001781_01334 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Acutalibacter|s__Acutalibacter sp000432995|m__MGYG000001781 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,36DD0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517657 0 0 0 0 0 0 0 1107882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVNIVPNST MGYG000002993_00787;MGYG000000262_01195;MGYG000004296_01958;MGYG000002517_01026;MGYG000001315_01699 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.6 186801|Clostridia 1.0 C 0.6 Psort location Cytoplasmic, score 0.6 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 602137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1143564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVNIVPNST(Formyl[T](Thr->Glu)GAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAVNIVPNSTGAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 37729595 59627023 33121903 33854829 36830164 43030360 22889784 42712067 26870756 41215756 50919554 49983722 53014521 20571197 30545102 49265807 42939631 15725789 17611874 37048554 49805825 0 22000777 21203276 37370850 24891835 37733561 19726878 36864672 39730434 17357939 32608944 27396549 23085312 32109528 25203661 30765416 31608747 48722513 109342209 32332872 39387484 54852950 26446238 50614088 40694332 34649165 34523068 41495960 31050659 47335748 24655933 26878796 22537924 33140998 0 27578907 47737930 40047785 19450771 62731234 57130554 32591402 33012965 41761898 101071898 87829694 52979727 121864068 53806285 34544076 49980487 49467634 51815438 35936739 52935103 42194807 0 39342877 42431672 15182921 40083022 29778391 53575272 18208234 39944590 36683977 56192342 35536566 27682130 45805354 60317906 48537361 39358583 60841011 48833746 43947009 0 70972302 33351180 37969711 42427206 58605500 90823352 56491963 0 33545902 0 88879198 0 41745365 25107039 33016075 44928388 12176569 2676636 2345257 4203335 3471926 1412348 3957157 10028690 6072146 1837771 1885439 9754355 5759568 6898032 10756549 1753594 2581803 0 2763660 3752853 11606445 882325 509948 282523 13513581 14006387 9112326 0 934434 5330597 347467 8490396 2110229 13069881 11972199 11452959 14221655 660409 142764778 0 0 0 47275553 0 0 134031362 127157770 216716494 144248141 205546689 51239932 229274423 190879904 134013141 171994880 23975288 0 0 178165815 114631010 46409834 141223266 176817115 129795155 168609594 52816606 169489869 89014993 143038809 138617348 281976655 0 113025565 174696021 153741909 147857634 -AAAVNIVPNSTGAAK(Cation_Na) MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 647042 1362154 360003 0 0 835735 321567 268815 0 270894 0 0 0 0 284396 0 706810 0 245616 984035 1246746 1570133 0 272882 0 267316 0 0 384807 0 0 620999 312200 0 0 291531 542506 688011 1623762 3444373 1018152 0 0 451287 1037775 696010 0 608917 0 0 0 0 424390 0 727877 0 627169 1178874 863109 0 0 1025599 0 678319 0 0 1638663 0 0 951912 976171 0 0 1514356 727132 1631914 1786266 4088087 0 0 0 1447739 1007541 1770585 0 1522671 0 0 0 0 1281762 0 1395114 0 1818032 1612951 1385189 2808109 0 873255 0 718007 0 0 1828439 0 0 4210477 3023196 0 0 780797 1044857 1373743 372800 239995 746630 0 0 262903 406544 215323 0 244406 0 0 0 0 489684 0 309797 0 298071 449755 476903 475809 0 243600 0 638717 0 0 0 0 0 472393 498323 0 0 378463 608324 404837 4572278 5742860 5781466 0 0 3652079 4769561 3807192 0 5910343 0 0 0 0 6060620 0 3955039 0 4925055 2267113 5149178 4561196 0 1745646 0 1910417 0 0 5195867 0 0 5543844 4947207 0 0 2079916 2181302 4050095 -AAAVSLDIPLYR MGYG000002492_02565 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2690069 0 0 0 0 1272919 0 0 0 0 1834420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAYFLMAK MGYG000000042_01529;MGYG000001835_02138 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes,2FP8W@200643|Bacteroidia,4AKSY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1946917 0 0 0 0 2480882 0 0 0 0 1890166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478604 0 0 0 0 466842 0 0 0 0 448845 0 0 0 0 0 0 0 0 0 0 -AAAYGPMC(Carbamidomethyl)QGIAKPVNDLSR MGYG000000242_02893 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,2681I@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Phosphate acetyl/butaryl transferase 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641387 0 0 0 0 1036814 0 0 0 0 1201171 0 0 0 0 0 0 0 0 0 0 -AAAYLGTVIGK MGYG000000201_02097;MGYG000000252_01803;MGYG000004733_00984;MGYG000004869_03336;MGYG000000301_00176;MGYG000000212_03063;MGYG000000171_01889;MGYG000000002_00866;MGYG000002966_02559;MGYG000000133_00061;MGYG000002298_00344;MGYG000000251_01815 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3XZZX@572511|Blautia 0.9166666666666666 186801|Clostridia 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 532585 589441 1189724 392401 0 2630881 234829 607353 226947 687859 1385644 879852 736693 325505 844741 1012910 751641 1074777 475288 512322 591714 2774245 1002854 1317538 530431 508318 456678 804274 1816519 489811 1314783 506329 1148161 586639 513574 429066 387633 1272689 0 331300 340865 0 0 0 464683 0 0 486398 0 0 372802 0 0 320618 389407 287548 0 267962 370251 0 294626 0 329359 285036 283310 296515 1467250 214449 646813 388970 0 0 317485 293270 350222 434107 856467 622678 923686 557752 0 1264103 552666 879046 591405 811341 397611 998693 631059 615629 925695 921110 1158194 646035 856406 807712 653143 1863944 386922 959186 843863 793327 987248 540225 984364 822796 1512344 1006463 1254146 1093074 797599 575694 874239 992453 0 876247 0 172362 0 0 0 0 0 0 365710 0 578904 257403 438384 691608 291499 0 0 0 0 0 0 0 0 0 0 477357 2938396 221609 1403476 303730 0 0 0 0 208374 544543 7247541 7778802 5647784 8676392 0 3278910 10926021 7497803 4329735 8571335 5734271 5983074 4468903 11518732 7501554 5516083 5639311 218058 6272046 1690820 9605431 5408714 234426 5880109 6624012 5449532 8413451 708358 10360098 1457866 5154822 7151519 8002803 8855380 4851370 7162753 3838083 4154454 -AAAYLGTVIGKK MGYG000000201_02097;MGYG000004733_00984;MGYG000004869_03336;MGYG000000301_00176;MGYG000000212_03063;MGYG000000171_01889;MGYG000000002_00866;MGYG000000133_00061;MGYG000002966_02559;MGYG000002298_00344;MGYG000000251_01815 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3XZZX@572511|Blautia 0.9090909090909091 186801|Clostridia 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 353234 609799 1134634 278908 0 2014333 77176 618592 286385 349239 890345 530636 680231 394396 556351 804930 557425 0 372336 0 427343 2108840 0 1145130 451705 452335 299527 0 1058783 0 1251887 484272 795892 226406 0 228527 301701 1049111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 621208 0 0 0 0 0 0 0 0 0 327419 477251 396459 171456 0 212684 97848 506101 0 272737 86712 276109 261773 119984 302548 433569 618558 0 272804 0 245265 999846 0 298936 159619 261576 350370 0 103780 0 608956 417599 355834 540703 0 0 209994 401953 0 549497 350791 0 0 94182 0 0 0 0 103780 0 197389 111551 0 194998 267495 0 0 0 0 335902 0 0 0 0 0 0 530482 0 481971 329068 141326 0 0 0 0 77020 3735871 4323782 4683117 6286982 0 2235308 6125013 2903065 2780021 6169163 4044625 4475865 3376161 6101993 4201888 3237002 4140593 0 3604992 0 6252843 0 0 4912913 3597169 2538473 5448415 0 5754407 0 3182507 4593325 6563540 3630129 0 3770566 2638940 2946787 -AAAYLGTVLGKK MGYG000000201_02097;MGYG000000301_00176;MGYG000000133_00061 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3XZZX@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2858255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAYPGIEIVPLK MGYG000001306_03249;MGYG000000781_01397;MGYG000003693_02828 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4656@1|root,COG4656@2|Bacteria,4NIS7@976|Bacteroidetes,2FMAQ@200643|Bacteroidia,4AM9Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4_10,Fer4_17,Fer4_7,Fer4_8,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1552250 0 0 0 0 2185547 0 0 0 0 1480303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212036 0 0 0 0 103354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247237 0 0 0 0 135531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAAYSASAK MGYG000000022_02021;MGYG000002040_00989;MGYG000002274_00825;MGYG000002619_02367;MGYG000001300_02195;MGYG000003166_00778;MGYG000003899_00633;MGYG000000195_02114 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WIV7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 1751630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2379769 1032685 1261585 1764540 0 0 2622715 0 0 0 2277135 3656089 0 0 0 0 0 0 0 0 0 0 0 3668303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5799343 1358486 6111918 3714904 0 0 4347478 0 0 0 5613039 4182012 0 0 0 0 0 0 0 0 0 0 0 1887269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 862219 0 448550 399486 0 0 0 0 0 0 1248097 3780831 0 0 0 0 0 0 0 0 0 0 0 1711773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1350454 928249 0 1540633 0 0 238373 0 0 0 1596684 1147416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295894 5638800 0 0 0 0 4283652 0 0 0 322019 571790 0 0 0 0 0 0 0 0 0 0 -AAAYVEIIC(Carbamidomethyl)K MGYG000002517_02724 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0119@1|root,COG2207@1|root,COG0119@2|Bacteria,COG2207@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) 1.0 leuA 1.0 - 1.0 2.3.3.13 1.0 ko:K01649 1.0 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 1.0 M00432 1.0 R01213 1.0 RC00004,RC00470,RC02754 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HMGL-like,HTH_18,LeuA_dimer 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-isopropylmalate synthase. isopropylmalate synthetase. Formerly EC 4.1.3.12. 3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+). 1.0 1.0 1.0 1.0 Pyruvate metabolism;2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 413405 0 0 0 0 0 0 0 264527 0 0 0 0 430460 0 0 285064 0 0 433362 395149 0 0 0 0 398626 0 0 0 0 0 0 0 0 0 0 326074 0 432320 0 0 0 0 0 0 0 453586 0 0 0 0 397798 0 0 403228 0 0 296695 238512 0 0 0 0 375667 0 0 0 0 0 0 0 0 0 0 632206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1386313 0 0 0 0 0 0 0 1871015 0 0 0 0 1667951 0 0 1642362 0 0 1557255 1607317 0 0 0 0 810217 0 0 0 0 0 0 0 0 0 0 0 0 996791 0 0 0 0 0 0 0 570570 0 0 0 0 1103529 0 0 0 0 0 544260 809221 0 0 0 0 818597 0 0 0 0 0 0 0 0 0 0 0 0 -AAAYWHAK MGYG000002506_02716 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG2375@1|root,COG2375@2|Bacteria,1R4TD@1224|Proteobacteria,1RY01@1236|Gammaproteobacteria,3XMHN@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 P 1.0 ferric-chelate reductase (NADPH) activity 1.0 yqjH 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010045,GO:0016491,GO:0016722,GO:0016723,GO:0019725,GO:0030003,GO:0033212,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050660,GO:0050662,GO:0050801,GO:0050896,GO:0051716,GO:0052851,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071289,GO:0071949,GO:0097159,GO:0098771,GO:1901265,GO:1901363 1.0 1.16.1.9 1.0 ko:K07229 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_9,PadR,SIP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ferric-chelate reductase (NADPH). NADPH:Fe(3+)-EDTA reductase. The enzyme, which is widespread among bacteria, catalyzes the reduction of ferric iron bound to a variety of iron chelators (siderophores), including ferric triscatecholates and ferric dicitrate, resulting in the release of ferrous iron.-!-The enzyme from the bacterium Escherichia coli has the highest efficiency with the hydrolyzed ferric enterobactin complex ferric N-(2,3-dihydroxybenzoyl)-L-serine. cf. EC 1.16.1.7 and EC 1.16.1.10. 2 a Fe(II)-siderophore + H(+) + NADP(+) = 2 a Fe(III)-siderophore + NADPH. 1.0 1.0 1.0 1.0 1.0 none 1.0 542832 0 199582 0 0 604892 0 645114 0 0 0 0 0 0 0 0 436925 0 710167 0 0 676804 0 790348 105324 201408 386198 0 300472 0 0 0 240675 471862 283804 0 370195 161242 143462 0 0 0 0 611127 0 247673 0 0 0 0 0 0 0 0 269362 0 0 0 0 729166 0 582069 0 0 33709 0 250247 0 0 0 672761 170271 208060 0 145866 443778 341741 0 67830 0 0 630560 0 280897 0 0 0 0 0 0 0 0 0 0 445534 0 0 311387 0 443653 193788 141982 154502 0 604637 0 0 0 65537 518986 357692 0 273544 74335 830540 0 607167 0 0 1259191 0 1167049 0 0 0 0 0 0 0 0 890347 0 525353 0 0 950760 0 635040 761184 730055 849971 0 604003 0 0 0 1173436 724938 1070828 0 903655 609141 0 0 0 0 0 0 0 38478 0 0 0 0 0 0 0 0 0 0 43154 0 0 0 0 85149 90124 72071 76349 0 15025 0 0 0 54578 47849 0 0 65948 0 -AAC(Carbamidomethyl)ADKFRK MGYG000000142_01590;MGYG000000171_01288 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG2407@1|root,COG2407@2|Bacteria,1TQ5Q@1239|Firmicutes,248V0@186801|Clostridia,3XZ8N@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185226 0 0 0 0 51242 0 0 0 0 140349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405481 0 0 0 0 0 0 0 0 0 1173815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAC(Carbamidomethyl)AGEVDGEIVDLR MGYG000002492_02065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WGVM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 - 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 625090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1237958 0 0 0 0 1107714 0 0 0 0 1468186 0 0 0 0 396841 0 0 0 0 0 0 0 1166204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364339 0 0 0 0 565164 0 0 0 0 728718 0 0 0 0 1265231 0 0 0 0 1106550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAC(Carbamidomethyl)AGEVDGEVVDLR MGYG000000204_01915;MGYG000000164_00182 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,25UXD@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 - 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAC(Carbamidomethyl)AGEVN(Deamidated)GEVVDLR MGYG000000171_01863;MGYG000000212_03088;MGYG000004785_00534;MGYG000001338_01044;MGYG000000200_00587;MGYG000001602_01700;MGYG000002298_00403 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3XYSJ@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 10.00 1.0 thrS 1.0 - 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAC(Carbamidomethyl)AGEVNGEVVDLR MGYG000000171_01863;MGYG000000212_03088;MGYG000004785_00534;MGYG000001338_01044;MGYG000000200_00587;MGYG000001602_01700;MGYG000002298_00403 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3XYSJ@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 10.00 1.0 thrS 1.0 - 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 686039 1067004 809717 0 0 0 0 0 0 0 1092620 349356 0 0 0 796505 0 952438 0 0 0 0 485862 0 0 494412 0 819224 0 0 657103 838511 444932 0 0 0 425799 708522 349223 1108806 0 0 0 0 0 0 0 0 0 0 0 0 0 164827 0 793204 0 0 0 0 445814 0 0 184426 0 593354 0 0 1377231 453920 0 0 0 0 187236 199003 424448 1546513 733912 0 0 0 0 0 0 0 503053 1003573 0 0 0 568510 0 0 0 0 0 0 0 0 0 600388 0 632150 0 0 1002313 1257580 579681 0 0 0 573215 704438 394957 1430677 558975 0 0 0 0 0 0 0 642291 508095 0 0 0 612720 0 0 0 0 0 0 0 0 0 460579 0 645330 0 0 1261540 1065357 862158 0 0 0 410540 1002338 0 1002110 748787 0 0 0 0 0 0 0 585279 481065 0 0 0 466909 0 737031 0 0 0 0 634410 0 0 296897 0 518370 0 0 924402 680261 963449 0 0 0 429933 853431 -AAC(Carbamidomethyl)C(Carbamidomethyl)HC(Carbamidomethyl)SMC(Carbamidomethyl)SEVC(Carbamidomethyl)PR MGYG000000077_01493;MGYG000000262_00349 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,25URU@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 RnfC Barrel sandwich hybrid domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 482696 283546 252299 0 0 0 310587 0 373164 278179 0 492438 0 390766 500697 313879 0 259472 0 0 448620 0 174270 326472 0 135195 0 446279 0 319185 246252 263735 0 0 0 0 0 502976 351836 0 362865 0 276257 751995 298640 0 275961 0 0 286499 126540 318082 0 277569 0 410794 437929 363869 201390 0 412268 460498 351032 377324 0 648658 0 262199 205729 0 406323 0 491932 241916 0 1033438 1155043 305003 1090297 0 1073170 0 782022 0 796216 795751 0 803015 710089 769996 845943 766052 0 1738209 1041590 942943 1658513 0 837129 994129 942812 1028830 0 539469 0 580665 1045548 515622 1008545 0 382770 619123 375207 340834 309555 0 0 0 531827 355766 0 0 528939 0 0 453271 320024 198136 344027 0 0 0 0 0 403543 0 192387 0 0 219620 0 0 0 0 0 0 0 0 0 0 0 941425 1637321 1472233 699651 0 835139 538477 723666 0 951538 1494158 0 1719893 649251 1028136 1781331 883802 0 1306417 1272495 571641 1304841 0 773272 811750 1038929 1217846 0 397788 0 1802368 1544067 1829139 1209264 0 990107 1382930 1277733 -AAC(Carbamidomethyl)DEFFKR MGYG000004797_02288;MGYG000002478_02020 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,4AKEY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 442000 332906 0 201138 312941 0 0 0 434040 0 0 624432 0 285627 0 0 0 367370 323646 547394 0 0 0 284980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436141 365905 0 390659 452493 0 0 0 544878 0 0 465697 0 376617 0 0 0 306265 410186 301417 0 0 0 460918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375346 338222 0 132574 320888 0 0 0 300899 0 0 329665 0 435642 0 0 0 176099 314240 283373 0 0 0 295002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380156 360950 0 111144 495561 0 0 0 0 0 0 364716 0 642719 0 0 0 0 971001 0 0 0 0 153308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582035 424858 0 653348 457093 0 0 0 844671 0 0 669413 0 772582 0 0 0 511591 560367 445892 0 0 0 681588 0 0 0 0 0 0 0 0 0 0 -AAC(Carbamidomethyl)DEFFR MGYG000003693_02571 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,4AKEY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460617 0 0 0 0 538676 0 0 0 0 417484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAC(Carbamidomethyl)DVYFEK MGYG000002438_01848 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,22WFC@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Domain of Unknown Function (DUF349) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 148825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 923764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1158444 0 0 0 0 0 0 0 0 -AAC(Carbamidomethyl)EALK MGYG000000002_01445 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A faecis|m__MGYG000000002 1.0 COG1653@1|root,COG1653@2|Bacteria,1TSGC@1239|Firmicutes,24A24@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3424535 0 1152031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3582360 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3656410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 626087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723350 0 967100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAC(Carbamidomethyl)EDAIR MGYG000001410_00463 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__Sutterella wadsworthensis_A|m__MGYG000001410 1.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,4PQEF@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 842982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 862898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAC(Carbamidomethyl)EEFGM(Oxidation)K MGYG000002794_01352;MGYG000002720_01439;MGYG000002057_00766 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG1609@1|root,COG1609@2|Bacteria,1TSVS@1239|Firmicutes,24CU2@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 Protein of unknown function (DUF3798) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF3798 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAC(Carbamidomethyl)EEFGMK MGYG000002794_01352;MGYG000002720_01439;MGYG000002057_00766 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG1609@1|root,COG1609@2|Bacteria,1TSVS@1239|Firmicutes,24CU2@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 Protein of unknown function (DUF3798) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF3798 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 3683927 0 0 3690657 2413743 3486090 4760347 3867152 3874890 0 0 0 0 3749079 3646594 0 3043603 0 0 0 3019394 2398304 0 3291857 3278666 4337942 3365085 0 0 0 1967881 0 0 3323658 4214984 3346319 3814194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 186242 0 0 0 0 0 287842 0 274859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294641 0 0 0 0 0 0 0 0 0 0 0 0 0 142313 0 0 343159 0 0 0 0 0 0 0 0 0 208846 238404 0 314206 0 0 0 506671 0 0 0 584203 461307 0 0 0 0 0 0 0 301101 0 168263 207442 0 0 0 0 0 0 0 128564 0 0 0 0 0 0 340914 266583 0 0 0 0 0 301670 430116 0 164481 89813 172873 233579 0 0 0 0 0 0 114964 0 0 125705 0 -AAC(Carbamidomethyl)EEMAK MGYG000002478_04117;MGYG000000243_00095 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 151411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAC(Carbamidomethyl)EPLLK MGYG000002272_00456;MGYG000004681_01722;MGYG000000573_00113;MGYG000001300_02210;MGYG000002040_00975;MGYG000003899_00619;MGYG000003166_00764;MGYG000002545_01135;MGYG000000195_02128;MGYG000000022_02035;MGYG000003921_00348;MGYG000002619_02381;MGYG000001157_01263;MGYG000001627_01317;MGYG000002610_01889;MGYG000000392_01456;MGYG000004732_00519;MGYG000000258_00286;MGYG000003937_00262;MGYG000002105_00236;MGYG000002641_00983;MGYG000002274_00840;MGYG000002224_01655 domain d__Bacteria 1.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3WJ9K@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome 1.0 rplV 1.0 - 1.0 - 1.0 ko:K02890 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L22 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 3307149 3704865 3442206 168919 2306014 3566255 0 0 0 0 2320233 186247 3678388 4868474 0 0 3030894 7678487 0 3566593 0 3437289 7275445 3262783 0 2570374 4700890 7013747 126347 2622258 2591443 0 3348463 0 5041980 3017239 4990623 3864455 4613710 3335165 3920015 4143212 1856257 2528819 0 0 0 0 2600810 4207387 2535086 3782564 0 0 3961654 4825586 0 4566656 0 2243361 7125593 2437052 4098487 3755217 3679963 5666771 693765 3576963 2886474 0 4228653 0 2403783 4179650 4502699 3208042 3097934 2682349 3028519 3505262 3106174 3260275 0 0 0 0 2803822 3101181 2857443 3076361 0 0 3264071 11392924 0 2647977 0 2945934 8296224 3369070 3193436 2747508 2437144 8608829 2193130 4211443 2660305 0 2368598 0 2239199 3084864 3340513 2552464 3207466 3557076 5377520 3365804 4199070 4918626 0 0 0 0 5037405 7321734 3829690 3347474 0 0 3132982 9368501 0 3715462 0 4346096 6013802 4428330 4244478 4388734 3767949 8846709 2949925 5118426 4885749 0 5462745 0 2439455 3647184 3598329 4718715 496098 898434 1579418 1085837 714173 896074 0 0 0 0 856498 2969321 925880 533627 0 0 927503 6590913 0 661648 0 657151 7769534 470198 765592 1077404 956037 5782738 1088116 488980 985428 0 1332756 0 1018894 564068 860169 1520863 -AAC(Carbamidomethyl)GNIIPSSTGAAK MGYG000003469_01436;MGYG000003542_01626 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 583813 0 0 0 0 0 391092 0 0 0 0 0 0 0 0 0 0 475917 0 -AAC(Carbamidomethyl)LLTISDSFTSHK MGYG000002485_00105 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0813@1|root,COG0813@2|Bacteria,3789D@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 F 1.0 purine-nucleoside phosphorylase 1.0 deoD 1.0 - 1.0 2.4.2.1 1.0 ko:K03784 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Metabolic pathways;Nicotinate and nicotinamide metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism 1.0 none 1.0 0 0 705993 0 0 0 0 0 0 0 0 837997 0 0 0 0 0 0 0 0 305506 0 0 0 0 0 0 0 0 0 0 0 300087 0 0 0 0 434699 0 0 621904 0 0 0 0 0 0 0 0 181608 0 0 0 0 0 0 0 0 1371341 0 0 0 0 0 0 0 0 0 0 0 522764 0 0 0 0 1158525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAC(Carbamidomethyl)QILEILLGE MGYG000002438_02292 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,22WFX@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 121376 0 0 0 0 0 0 0 0 0 0 0 132955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403440 0 0 0 0 0 0 93951 0 694824 0 0 0 140075 0 0 0 0 0 0 4314360 2797250 0 0 0 0 0 0 0 0 0 0 0 0 221645 0 0 0 287053 0 4616106 0 0 0 0 1146060 0 164446 0 0 0 265147 0 0 0 0 0 0 183407 177776 0 0 0 0 0 0 0 0 0 0 0 0 480783 0 0 0 126403 0 861896 0 0 0 0 287575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563127 0 0 0 1842180 0 418150 0 0 0 0 0 0 3434999 0 0 0 5321644 0 0 0 0 0 0 3028309 3522927 0 0 0 0 0 0 0 0 0 0 0 0 2936361 0 0 0 8417067 0 3926479 0 0 0 0 719155 0 -AAC(Carbamidomethyl)WLLLSR MGYG000002478_00957 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,2FNRM@200643|Bacteroidia,4AKT2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 290501 560505 99611 498526 982561 457986 520833 382323 371156 0 116639 0 162658 0 219150 90856 422434 116006 378618 364184 291012 287258 114092 456242 0 441621 448982 418094 818491 420223 0 814934 271348 420073 106680 0 142229 285112 544614 176311 616314 677766 1486341 0 484695 398229 493340 0 542737 0 268813 0 621414 857698 442131 516316 0 285392 165494 103633 817707 0 0 668084 628283 559649 0 0 0 847436 0 294616 640301 0 0 398643 0 0 0 0 0 0 0 0 0 0 0 0 121229 0 0 71201 0 138496 156804 0 0 119220 0 0 0 0 0 0 0 0 0 0 0 175902 339020 0 0 0 90210 0 175100 0 184326 0 0 0 0 0 1032386 0 0 0 84801 0 0 862071 0 0 0 0 0 233811 0 0 265047 368573 0 0 0 191237 0 0 0 0 0 0 1018395 794771 1011676 1133363 1915368 1019195 772518 962200 816209 0 601571 0 626237 0 770989 751239 1051777 3033304 883651 1187197 687289 875222 2430817 870011 0 900094 917558 2371338 1400665 1053036 0 1364362 537074 862440 984214 0 891353 819184 -AAC(Carbamidomethyl)YLVR MGYG000003425_04484;MGYG000002025_01320;MGYG000003452_00823;MGYG000000099_02716;MGYG000001292_00841;MGYG000001300_00435 domain d__Bacteria 1.0 COG4716@1|root,COG4716@2|Bacteria,2GKZ8@201174|Actinobacteria,4CYZK@85004|Bifidobacteriales 0.3333333333333333 186801|Clostridia 0.5 S 1.0 MCRA family 0.6666666666666666 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1633874 0 0 0 762884 0 0 0 1117924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1173693 0 0 0 0 0 0 0 0 0 1112586 1025150 0 623822 0 0 0 626523 0 0 0 709441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 566500 0 0 0 0 0 0 0 0 0 801157 811739 0 326869 0 0 0 605019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 583205 0 0 0 0 0 0 0 0 0 586208 548129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134219 0 0 -AAC(Cys->Ala)GNIIPSSTGAAK MGYG000003469_01436;MGYG000003542_01626 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1645929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6550396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1071888 0 1095284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAC(Cys->Asp)PNTYIISSR MGYG000002794_01702 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp003487665|m__MGYG000002794 1.0 COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia,2N8Z1@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate-binding protein PnrA-like 1.0 - 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2994094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 580889 0 0 0 0 -AAD(Asp->Asn)EVGALIDK MGYG000001338_01847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,NAD_binding_7,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAD(Asp->Xle)AAQPK MGYG000001661_03158;MGYG000003681_01989 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,2FM1B@200643|Bacteroidia,4AM7E@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate 1.0 deoD 1.0 - 1.0 2.4.2.1 1.0 ko:K03783 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Metabolic pathways;Nicotinate and nicotinamide metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4607133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAD(Asp->Xle)LDAIHDTVHEMAR MGYG000004733_01319 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3WGYN@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAAAAIGE(Glu->Lys)GLQAFC(Carbamidomethyl)IPGSVADHR MGYG000000245_00061;MGYG000000404_00348;MGYG000002517_01686;MGYG000002492_01963;MGYG000004055_00746 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 0.8 183925|Methanobacteria 0.8 F 0.8 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 0.8 purD 0.8 - 1.0 6.3.4.13 0.8 ko:K01945 0.8 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 0.8 M00048 0.8 R04144 0.8 RC00090,RC00166 0.8 ko00000,ko00001,ko00002,ko01000 0.8 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 0.8 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 0.8 0.8 0.8 0.8 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 0.8 none 1.0 0 0 0 0 0 77591 0 0 0 0 0 0 0 0 0 0 0 0 119188 0 0 319893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8799893 0 0 0 0 0 0 0 0 0 0 0 0 19860601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1823383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAAAAIGEGLQAFC(Carbamidomethyl)IPGSVADHR MGYG000000245_00061;MGYG000000404_00348;MGYG000002517_01686;MGYG000002492_01963;MGYG000004055_00746 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 0.8 183925|Methanobacteria 0.8 F 0.8 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 0.8 purD 0.8 - 1.0 6.3.4.13 0.8 ko:K01945 0.8 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 0.8 M00048 0.8 R04144 0.8 RC00090,RC00166 0.8 ko00000,ko00001,ko00002,ko01000 0.8 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 0.8 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 0.8 0.8 0.8 0.8 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 0.8 none 1.0 9387187 0 0 342225 994190 387080 551600 10265876 326992 639620 314886 13322968 0 401210 393332 0 285956 0 251203 0 0 4527903 0 905094 0 375764 359025 0 0 12692355 0 0 0 17603997 20690653 0 368000 0 213264 0 0 311432 4861656 2958467 286354 803308 758433 440028 7383297 1265252 0 879557 723505 0 1619184 0 938590 0 0 1537649 0 591960 0 159353 916870 0 0 1070876 0 0 0 955749 563913 0 371087 0 1343314 0 0 1801237 447104 592480 444471 4638132 8311175 529742 9885706 441264 0 306122 507109 0 2949267 0 304985 0 0 665194 0 766094 0 22661521 683869 0 0 163920 0 0 0 367728 135205 0 382835 0 20070071 0 0 15435846 21919714 16111015 19313203 54797110 53964470 9977597 10344772 11027593 0 51247310 38300166 0 26835646 0 23403603 0 0 729442 0 980581 0 18937550 39677070 0 0 12549642 0 0 0 22419226 23847481 0 29582551 0 4851213 0 0 3607056 19449426 10798868 16120452 3131034 39178207 18545173 69719233 20414270 0 8520228 52425434 0 0 0 26059087 0 0 0 0 52351115 0 17007500 74848734 0 0 23495529 0 0 0 30841085 72766664 0 100229935 0 -AADAAAAIGEGLQAFC(Carbamidomethyl)IPGSVADHRK MGYG000000245_00061;MGYG000000280_02029;MGYG000000136_01348;MGYG000000002_01850;MGYG000000404_00348;MGYG000002517_01686;MGYG000000018_02387;MGYG000002492_01963;MGYG000004055_00746 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 0.6666666666666666 183925|Methanobacteria 0.6666666666666666 F 0.6666666666666666 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 0.6666666666666666 purD 0.6666666666666666 - 1.0 6.3.4.13 0.6666666666666666 ko:K01945 0.6666666666666666 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 0.6666666666666666 M00048 0.6666666666666666 R04144 0.6666666666666666 RC00090,RC00166 0.6666666666666666 ko00000,ko00001,ko00002,ko01000 0.6666666666666666 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 0.6666666666666666 none 1.0 1001342 664769 626948 1238175 657152 609824 727280 1170987 955038 1144446 1241157 951631 881144 845757 1274917 551303 956478 583494 1098286 807313 977899 815321 630612 1126855 984176 1055372 2032355 1203330 0 1362029 0 631253 565908 0 0 1216199 1920289 461777 100599 47169 165944 182865 246708 42269 197716 173298 32688 120513 191620 46549 559164 230896 383979 663396 519815 813908 84748 145062 575627 94493 232508 250442 437527 149303 254001 767021 0 1898855 0 407088 1415117 0 0 727896 440962 187543 947080 318039 308904 94859 1812565 2352936 3025483 0 4996762 5079863 2662107 0 3141219 1139196 0 4222573 179055 120494 2860581 2314321 1529091 554457 282500 0 4478899 5071731 2995839 2174649 0 0 0 3409465 9878322 0 0 0 0 8770667 1991156 0 2656966 12143487 6587207 0 1656313 4358788 4124277 5711309 4556413 1761272 3944979 5286631 6067453 0 6204923 0 8557546 5886060 17025032 3143412 0 0 18158786 0 6765437 0 0 9176856 0 6408955 0 0 0 13199157 17448081 178962 4431048 13627303 0 0 5068203 5987157 8085688 5740639 16875778 12491112 22587608 9709397 2999492 15981390 18863333 5643954 7890746 7978835 12659351 5766150 13556805 17722458 0 17717931 25897455 0 25356322 0 0 7799644 0 402422 9818178 0 0 7803267 19805986 12232727 -AADAAAAIGEGLQAFC(Carbamidomethyl)IPGSVADTR MGYG000002025_00960;MGYG000001619_00078;MGYG000000142_02731;MGYG000000133_00506;MGYG000001338_01296;MGYG000001970_01269;MGYG000000212_00326;MGYG000000301_00647 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.625 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.87 0.625 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6159000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4077568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155668 0 0 0 0 0 0 0 0 0 0 359209 383686 0 0 0 0 430060 0 0 4793957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93286 0 0 0 0 0 0 0 855990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224004 99675 0 0 0 0 0 0 0 28893726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30132321 0 0 0 0 0 0 0 0 0 0 32977095 85756023 0 0 0 0 18104448 -AADAAAAIGEGLQAFC(Carbamidomethyl)IPGSVADTRK MGYG000001619_00078;MGYG000000142_02731;MGYG000000133_00506;MGYG000001338_01296;MGYG000000301_00647 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.6 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.87 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3782281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24895995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAAQPK MGYG000001661_03158;MGYG000003681_01989 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,2FM1B@200643|Bacteroidia,4AM7E@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate 1.0 deoD 1.0 - 1.0 2.4.2.1 1.0 ko:K03783 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Metabolic pathways;Nicotinate and nicotinamide metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism 1.0 none 1.0 167127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217440 0 0 0 0 0 406923 0 0 0 0 0 0 0 0 0 0 112804 0 225227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297034 0 0 0 0 0 265654 0 0 0 0 0 0 0 0 0 0 454762 0 262468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208701 0 0 0 0 0 327053 0 0 0 0 0 0 0 0 0 0 171935 0 171684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355654 0 0 0 0 0 83757 0 0 0 0 0 0 0 0 0 0 171419 0 193243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293367 0 0 0 0 0 243730 0 0 0 0 0 0 0 0 0 0 272892 0 -AADAASYSGAEGDTADGAELTGWSGESR MGYG000002517_02514 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system 1.0 metN 1.0 - 1.0 - 1.0 ko:K02071 1.0 ko02010,map02010 1.0 M00238 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.24 1.0 - 1.0 - 1.0 ABC_tran,NIL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADADDEKTQSFVTK MGYG000002517_00614 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 PFAM Extracellular ligand-binding receptor 1.0 braC 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 1.0 none 1.0 239838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273966 403621 0 0 0 0 0 0 0 0 0 0 113094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2629056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3659707 3236542 0 0 0 0 0 0 0 0 2722667 0 3395543 0 438340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 523492 704201 0 0 0 0 0 0 0 0 234370 0 174800 0 -AADAETVDR MGYG000002494_01389 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,3XNR8@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 L-aspartate:2-oxoglutarate aminotransferase activity 1.0 aspC 1.0 GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.0 2.6.1.1,2.6.1.57 1.0 ko:K00813,ko:K00832 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 M00024,M00025,M00034,M00040 1.0 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 iPC815.YPO1410,iSFxv_1172.SFxv_1000 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. | aromatic-amino-acid transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. | L-methionine can also act as donor, more slowly.-!-Oxaloacetate can act as acceptor.-!-Controlled proteolysis converts the enzyme to EC 2.6.1.1. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. | 2-oxoglutarate + an aromatic L-alpha-amino acid = an aromatic oxo-acid + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1108520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1007429 0 0 0 0 721843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAEVENK MGYG000000089_01706 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2293901 0 0 0 0 2624385 0 0 0 0 2346951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAFNTILENAR MGYG000000133_01741 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 2E3QR@1|root,32YNK@2|Bacteria,1VENX@1239|Firmicutes,24QVR@186801|Clostridia,3Y0KX@572511|Blautia 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1292 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 372357 0 270743 0 0 472058 0 0 394204 564839 0 0 247166 233054 887278 0 0 0 0 0 647036 411028 0 319230 491261 766815 0 0 464001 0 399810 552239 370466 0 367491 439802 695740 417496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134025 0 0 0 0 0 290847 0 0 0 0 0 0 175658 234964 0 163683 0 0 0 0 222923 449436 262197 177420 0 0 232446 510140 0 0 0 0 0 293466 215373 0 0 330413 0 0 0 346061 0 181689 422662 217585 0 325323 277246 279047 0 317705 0 230304 0 0 238646 0 430721 264706 427195 0 0 157777 497601 647600 0 0 0 0 0 0 0 0 276605 516344 462965 0 0 273281 0 256663 0 266587 0 323848 328312 108769 308041 1504984 0 1267808 0 0 677661 0 1564364 1011872 1940462 1637812 0 1526996 3162476 1176716 0 0 0 0 0 1665210 1071115 0 984477 1603878 1360275 0 0 2431505 0 1473424 2018111 2076948 0 1547621 1541072 981418 1163267 -AADAGSLEGK MGYG000000243_00992;MGYG000002478_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,4NFEB@976|Bacteroidetes,2FMPN@200643|Bacteroidia,4AMY0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 electron transport complex, RnfABCDGE type, B subunit 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_4,Fer4_6,Fer4_7,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1830072 837149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 954676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 917420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAGSLEGKLC(Carbamidomethyl)PVGGAPVM(Oxidation)EK MGYG000000243_00992;MGYG000002478_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,4NFEB@976|Bacteroidetes,2FMPN@200643|Bacteroidia,4AMY0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 electron transport complex, RnfABCDGE type, B subunit 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_4,Fer4_6,Fer4_7,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAGVANIK MGYG000001400_00237 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Erysipelatoclostridium|s__Erysipelatoclostridium ramosum|m__MGYG000001400 1.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 family 4 1.0 - 1.0 - 1.0 3.2.1.86 1.0 ko:K01222 1.0 ko00010,ko00500,map00010,map00500 1.0 - 1.0 R00839,R05133,R05134 1.0 RC00049,RC00171,RC00714 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GT4 1.0 - 1.0 Glyco_hydro_4,Glyco_hydro_4C 1.0 3.2.1.86 1.0 GH4 1.0 GH4 1.0 GH4 1.0 6-phospho-beta-glucosidase. phosphocellobiase. Also hydrolyzes several other phospho-beta-D-glucosides, but not their non-phosphorylated forms. 6-phospho-beta-D-glucosyl-(1->4)-D-glucose + H2O = D-glucose + D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis;Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2415736 0 3780165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 829672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAGVTPK MGYG000001300_02006;MGYG000003166_01216 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3WGEI@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation 1.0 metG 1.0 - 1.0 6.1.1.10 1.0 ko:K01874 1.0 ko00450,ko00970,map00450,map00970 1.0 M00359,M00360 1.0 R03659,R04773 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,tRNA-synt_1g,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 GH84 1.0 methionine--tRNA ligase. MetRS. In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9. ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis;Selenocompound metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1570400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAIQNAPEVK MGYG000002478_01138 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG3883@1|root,COG1196@2|Bacteria,COG3883@2|Bacteria,4P07U@976|Bacteroidetes,2FN9Y@200643|Bacteroidia,4APBT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 nuclear chromosome segregation 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Collagen,DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1340056 0 1274611 1770351 1143412 0 0 0 0 0 1049018 2686733 0 0 1912996 0 1650787 0 0 0 1058438 1805589 1123306 0 0 0 1450919 1095440 0 0 0 0 0 2091792 1480723 0 0 0 0 0 2294849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAKEPAVK MGYG000000013_00619 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp902362375|m__MGYG000000013 1.0 COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,2FMRY@200643|Bacteroidia,4AMCU@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glycosyl hydrolase 57 family 1.0 amyA 1.0 - 1.0 3.2.1.1 1.0 ko:K07405 1.0 ko00500,ko01100,map00500,map01100 1.0 - 1.0 R02108,R02112,R11262 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH57 1.0 - 1.0 Glyco_hydro_57 1.0 - 1.0 GH57 1.0 GH57 1.0 GH57 1.0 alpha-amylase. glycogenase. Acts on starch, glycogen and related polysaccharides and oligosaccharides in a random manner; reducing groups are liberated in the alpha-configuration.-!-The term 'alpha' relates to the initial anomeric configuration of the free sugar group released and not to the configuration of the linkage hydrolyzed. Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units. 1.0 1.0 1.0 1.0 Metabolic pathways;Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADALAK MGYG000002293_00140;MGYG000001056_00145;MGYG000001770_02072;MGYG000003697_01831 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 346658 0 0 0 0 229195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 279930 0 0 0 0 0 0 0 0 0 0 0 363538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363862 0 0 0 0 0 0 0 0 0 0 0 751988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1091088 0 0 0 0 0 0 1128412 0 0 0 0 2806105 0 0 0 0 1029528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442975 0 0 0 0 0 0 231530 0 0 0 0 0 0 0 0 0 355618 0 0 0 0 0 0 0 0 0 0 -AADALRLPDWDAK MGYG000002506_04122;MGYG000002494_02896 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 S 1.0 abc transporter atp-binding protein 1.0 yjjK 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 1.0 3.6.3.25 1.0 ko:K06020 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ABC_tran,ABC_tran_Xtn 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ABC-type sulfate transporter. sulfate-transporting ATPase. An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.-!-The enzyme from Escherichia coli can interact with either of two periplasmic binding proteins and mediates the high affinity uptake of sulfate and thiosulfate.-!-May also be involved in the uptake of selenite, selenate and possibly molybdate.-!-Does not undergo phosphorylation during the transport.-!-Formerly EC 3.6.3.25. ATP + H2O + sulfate(out) = ADP + H(+) + phosphate + sulfate(in). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 189199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378376 0 453212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 810621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1113047 0 866129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479885 0 574809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAMVK MGYG000000262_00362 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,25WKA@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1071089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1414995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAPSGNVITKK MGYG000002517_00472 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3728727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAVGEDM(Oxidation)SK MGYG000000022_01831 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179764 0 0 0 0 234065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388378 0 0 0 0 580322 0 0 0 0 693173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444494 0 0 0 0 188821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADAVGEDMSK MGYG000000022_01831 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194017 0 0 0 0 0 0 0 0 0 142565 298658 0 452199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1234948 0 0 0 0 2580913 0 0 0 0 1708702 485065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5725554 0 0 0 0 4522697 0 0 0 0 4159233 902800 0 1106956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4160379 0 0 0 0 3189908 0 0 0 0 2453821 177752 0 0 0 0 0 0 0 0 0 -AADD(Cation_Fe[II])AAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 932168 644771 0 985419 394142 643358 0 368815 680280 548608 0 0 0 0 510766 0 654951 0 332430 681053 0 562983 0 497197 569931 699998 685468 0 0 0 247874 0 0 1334997 759822 0 979168 0 210595 182821 0 0 444854 94702 0 0 313655 98892 0 0 0 0 150956 0 170593 0 0 0 0 0 0 0 0 132419 0 0 0 0 156058 0 0 205539 143543 0 192788 0 106355 0 0 0 551562 157677 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444826 0 0 0 0 0 0 0 2944179 1009265 0 2992823 1598566 1121153 0 4409487 3736268 1826711 0 0 0 0 4320687 0 2028503 0 3335897 2838660 0 452253 0 218617 5102540 5044628 3115165 0 0 0 1007244 0 0 4561785 3924289 0 4288232 0 3066296 2127411 0 1207623 4641372 3257701 0 2026055 2763325 2776062 0 0 0 0 3768581 0 3204104 0 2408606 3233308 0 3145144 0 1565675 1713660 1221068 1168100 0 0 0 2264239 0 0 2679084 1237420 0 2244216 0 -AADD(Cation_Na)AAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4095284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDA(Ala->Gly)AGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLAISEK MGYG000001777_01359;MGYG000003422_01458;MGYG000000362_01735;MGYG000003422_01457;MGYG000000217_00038;MGYG000002934_00200;MGYG000001814_01561;MGYG000001514_01163 domain d__Bacteria 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae 0.375 186801|Clostridia 0.75 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 0.625 - 0.75 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 6476154 5672430 5063094 6735068 0 5894585 8408148 6817048 0 0 0 0 6002811 6779870 0 5437039 0 13092774 0 5740380 0 4353205 15823285 6280746 4506275 0 6378571 14442163 0 0 0 6236745 5782611 0 0 0 0 4548977 281752 0 0 253025 0 0 0 275335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305950 586519 0 0 0 0 0 129306 0 0 0 341190 0 0 0 374183 0 0 0 0 0 0 0 0 0 486790 170179 0 569833 0 347506 0 0 0 0 463769 0 0 178772 0 0 0 0 0 0 0 0 0 0 0 0 542741 217377 1314599 0 0 760126 506959 221046 0 0 0 0 825596 0 0 863739 0 1615691 0 0 0 979676 2339884 912126 519114 490682 559160 916601 0 0 0 635132 831862 0 0 0 421467 965336 0 0 0 0 0 331554 0 0 0 0 0 0 876714 0 0 497230 0 641181 0 0 0 0 497355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLS(Deoxy[S](Ser->Ala)ISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 6598470 6217756 0 0 0 0 5450928 0 0 0 0 0 6029909 0 0 0 0 0 0 0 0 0 0 0 0 6892989 0 6928855 6546811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLS(Formyl[S](Ser->Asp)ISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLS(Methyl[S](Ser->Thr)ISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14636704 9868983 0 0 0 10832275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8615587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1512592 0 0 0 0 0 0 0 0 0 0 2656517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28343328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLSIS(Formyl[S](Ser->Asp)EK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLSISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 19405073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 622744 0 0 2720961 0 0 0 380025 2708881 3123282 0 1818237 539306 0 497192 1166892 2539207 1514021 0 0 0 1946516 587898 0 385497 1062024 625350 0 0 0 0 1077656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14521803 0 0 4332144 0 1258082 854620 0 3825103 0 0 0 0 0 0 0 0 1011831 0 3917193 2944119 3578847 3264183 2890367 3510609 3658622 4147376 3982552 4499850 3353904 4239804 2843737 3184400 4100187 2574132 3193457 12914156 3071399 2812835 3597497 3008637 16546976 2820252 4198327 4280180 3766749 0 3322140 3817743 3226420 3925908 3031279 0 3881256 0 3899165 3463835 1048366 609666 2048895 1253343 2374685 897263 736871 840026 159849 0 846460 1478946 537556 584981 0 522687 0 1633697 798079 0 4054688 1217250 1433234 797242 863533 1001498 786450 1386198 810412 0 0 1055485 1162012 0 764550 782209 0 1972976 -AADDAAGLSISEKM(Oxidation)R MGYG000004317_00093;MGYG000000562_01318;MGYG000000562_01835;MGYG000001637_00105;MGYG000000187_02828;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000000154_02141;MGYG000003215_00935;MGYG000004414_00337 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.8181818181818182 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLSISEKMR MGYG000004317_00093;MGYG000000562_01318;MGYG000000562_01835;MGYG000001637_00105;MGYG000000187_02828;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000000154_02141;MGYG000003215_00935;MGYG000004414_00337 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.8181818181818182 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLT(Formyl[T](Thr->Glu)ISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLT(Thr->Ser)ISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9607584 0 0 0 0 0 4760437 0 3149519 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLTIS(Formyl[S](Ser->Asp)EK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLTISE(Cation_Na)K MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 846536 0 0 474359 478037 0 349013 288581 417653 396642 0 0 0 0 402177 0 841354 0 453739 723842 0 0 0 0 484056 437917 547717 0 0 0 0 0 0 1232272 761025 260641 1159746 387375 288158 0 1031427 177158 0 0 0 0 0 230396 0 0 0 0 351399 0 0 0 0 0 0 0 0 0 354718 179704 0 0 0 0 0 0 1016333 0 0 566420 0 1099335 475564 0 730651 492533 419715 0 0 322042 442555 0 0 0 0 0 0 0 0 0 403244 0 0 0 0 0 0 0 0 0 0 0 0 0 498783 0 551178 0 0 681244 0 0 1377854 0 2350725 0 2445630 5572764 4312118 2373538 0 0 0 0 5072367 0 2908787 0 3684334 3689588 0 0 0 0 8185556 7586126 4079273 0 0 0 0 0 912290 6132163 4644392 4705181 0 1014578 3063148 0 2179839 1350653 4042734 0 1564545 1845001 2812513 2905008 0 0 0 0 3632976 0 3048947 0 0 3176495 0 0 0 0 1165447 1158483 1117360 0 0 0 0 0 817039 3221529 1009030 971245 2285454 3302703 -AADDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 53126657 34630766 24247668 83426857 28813555 40674025 59489068 40522948 56082677 45782925 67626459 67363413 40324167 49122146 49541010 36050736 60455373 19740710 37643204 43669699 55295460 35203746 24812607 50275783 49741131 55127757 58356908 22286573 48076263 86471129 24956877 28079102 26241552 81892369 41294159 44762841 57697175 17873719 0 0 49005622 12588198 49999827 0 9584885 12256794 14481743 13277388 58469790 17752635 23410369 12517285 14774766 24688994 12828454 29913607 10010980 8839694 11291873 0 46619819 8277052 12278506 13228202 10896136 36478366 3638888 14643905 18943630 27346653 50845587 12658123 10472837 10463196 12300382 66738060 458730 2618110 41055060 273342 31583672 5881865 4925311 1843502 4181825 3214094 35883403 20667422 14142681 3411465 120256 14838590 3915922 3898195 89765 265342 3128923 190311 3468709 6100397 314661 2301084 789275 2969147 2497311 9770735 27098104 6012220 32093057 668765 296139 4355462 1157262 38780378 269736598 67427994 82976242 238332764 131460588 92701041 169576721 400616880 310412412 146699105 110079036 230563716 86631446 333877395 374030912 95037194 214465654 22759006 240587262 241446309 252787754 29369590 31885314 0 380907501 420408938 257253336 18809355 68790321 233502900 65863836 110148307 73713306 390212522 345337044 333111730 400530591 57748248 163879913 101611870 146604747 68808721 225587619 222816042 110437349 116462726 181580481 213512805 148201696 0 191888780 112865977 211098614 134675319 182715484 9243904 169445118 212111563 101752100 151294864 8762957 176095061 170956177 169140022 130963058 9001601 39150595 193129708 0 68154420 88630338 175979009 135363950 155785456 292824148 173627747 -AADDAAGLTISEK(Carbamidomethyl[K](Gly) MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLTISEKM MGYG000000489_01309;MGYG000001637_00814;MGYG000002492_03078;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.75 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 495869 0 0 0 0 0 0 505721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477465 0 0 0 0 463890 0 267672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3791753 0 0 0 1906316 0 2635519 8226203 5203467 0 0 0 0 0 8670406 0 3759155 0 0 0 0 0 0 0 4796971 5353395 4039538 0 0 3698864 0 0 0 6104251 6061887 4199280 6782436 0 0 0 0 0 0 0 284437 0 0 0 0 0 0 0 0 0 148822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265316 0 -AADDAAGLTISEKM(Oxidation)R MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.8 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDAAGLTISEKMR MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.8 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Salmonella infection;NOD-like receptor signaling pathway;Plant-pathogen interaction;Flagellar assembly;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDNHYVAYN(Deamidated)GYVAGR MGYG000001489_02354 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides goldsteinii|m__MGYG000001489 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1326854 0 0 0 977031 0 0 0 736105 550569 0 180757 0 0 367039 0 0 0 0 576628 0 0 0 0 320407 608065 0 0 472178 686873 0 796303 0 0 0 0 1505262 0 741108 0 0 0 701314 0 0 0 1160148 416598 0 612648 0 0 489162 589890 0 0 0 508100 0 0 0 0 0 0 0 0 417760 389134 0 968127 0 0 0 0 730375 0 940503 0 0 0 872319 0 0 0 862214 696028 0 377324 0 0 430388 534519 0 0 0 431013 0 0 0 0 583220 731901 0 0 760096 813767 0 485403 0 0 0 0 869082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2005783 0 0 0 2641215 0 0 0 1554437 1023626 0 883434 0 0 767817 2243443 0 0 0 2334845 0 0 0 0 992271 1081984 0 0 1009487 874059 0 1016302 0 0 0 0 1099808 0 -AADDNHYVAYNGYVAGR MGYG000001489_02354 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides goldsteinii|m__MGYG000001489 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572049 489695 429912 0 691498 652184 463926 683598 642516 890298 0 0 1153311 0 496984 715870 648105 0 732830 813095 0 797560 0 978148 606219 638870 0 0 841884 695916 700077 891271 426460 959715 0 0 678229 615964 -AADDPSMHSSQNEQDSR MGYG000000013_02894;MGYG000003922_02595;MGYG000000003_01690;MGYG000000236_04031;MGYG000000196_04786;MGYG000001346_02973;MGYG000004830_00176;MGYG000002549_01331;MGYG000004899_00047;MGYG000001313_02737;MGYG000000243_02436;MGYG000003367_02060;MGYG000001666_01147;MGYG000001345_02148 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG4231@1|root,COG4231@2|Bacteria,4NJM1@976|Bacteroidetes,2FMYS@200643|Bacteroidia,4AN7N@815|Bacteroidaceae 0.7857142857142857 976|Bacteroidetes 1.0 C 1.0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates 1.0 iorA 1.0 - 1.0 1.2.7.8 1.0 ko:K00179 1.0 - 1.0 - 1.0 - 1.0 - 1.0 br01601,ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 indolepyruvate ferredoxin oxidoreductase. IOR. Preferentially utilizes the transaminated forms of aromatic amino acids and can use phenylpyruvate and 4-hydroxyphenylpyruvate as substrates.-!-This enzyme, which is found in archaea, is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = (indol-3- yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1046173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 997468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 782697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDQNVAISAR MGYG000002298_00329 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp000436615|m__MGYG000002298 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 1376110 0 0 0 0 0 0 0 0 0 0 0 0 0 774357 0 1037695 0 481994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102428 0 215352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392771 0 0 0 0 0 0 0 0 0 0 0 0 0 220178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADDQNVVIAAR MGYG000004733_00969 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 537662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1132323 0 462391 0 0 0 0 0 0 770614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADEAAAPAVVEEGGLHK MGYG000001364_01116;MGYG000003693_02590 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3367172 0 0 0 0 5320503 0 0 0 0 4211470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 677073 0 0 0 0 559146 0 0 0 0 516295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADEADNNTLSPIYLK MGYG000003681_00782 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,4ANQH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 324419 0 0 0 445859 0 342813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334043 0 0 0 415934 0 0 0 0 0 0 0 422235 0 0 0 1635317 0 1381328 0 0 0 0 0 0 0 0 0 1247700 0 0 0 0 0 0 0 0 0 1234155 0 0 0 846309 0 975977 0 0 0 0 0 796813 0 0 0 636212 0 790809 0 0 0 0 0 0 0 0 0 434049 0 0 0 0 0 0 0 0 0 779183 0 0 0 641767 0 587743 0 0 0 0 0 329652 0 0 0 491355 0 365002 0 0 0 0 0 0 0 0 0 345412 0 0 0 0 0 0 0 0 0 240029 0 0 0 303456 0 431351 0 0 0 0 0 476972 0 0 0 607514 0 449142 0 0 0 0 0 0 0 0 0 598349 0 0 0 0 0 0 0 0 0 752930 0 0 0 732577 0 474091 0 0 -AADEADNTTLSPIYLK MGYG000001313_02385 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,4ANQH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 473776 0 0 0 0 0 0 0 0 0 0 0 0 0 523544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364948 439291 0 246463 0 0 0 0 0 0 0 0 0 0 0 0 0 1328046 0 0 0 0 0 0 0 0 954945 0 2004302 0 0 0 0 1722720 0 0 0 0 1473955 1127224 0 965413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756167 0 0 0 0 641175 435633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338815 0 0 0 0 0 0 0 0 268047 0 0 0 0 0 0 0 0 0 0 0 376210 335000 0 369026 0 0 0 0 0 0 0 -AADEC(Carbamidomethyl)GEDIVSQPDISVTQIEK MGYG000004735_02622 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 761019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1896945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADEC(Carbamidomethyl)GLELVSQPK MGYG000000187_01475 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,2FM4H@200643|Bacteroidia,4AKBP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 - 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1253178 0 0 0 0 1177231 0 0 0 0 691516 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 602392 0 0 0 0 643949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADEETLAR MGYG000002026_01136 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__HGM13010|s__HGM13010 sp900754965|m__MGYG000002026 1.0 COG1638@1|root,COG1638@2|Bacteria,1UCYF@1239|Firmicutes,24BR8@186801|Clostridia,2N6XY@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein, family 7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DctP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1541038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADEGWEIAVVPK MGYG000000212_00409 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG1879@1|root,COG1879@2|Bacteria,1TRBC@1239|Firmicutes,24DQX@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 767641 0 0 0 0 1101123 0 908955 0 0 0 0 0 0 0 505717 305970 0 0 1286155 0 1143205 0 603713 0 554223 0 0 1729288 0 0 0 0 510801 0 0 583045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468602 0 0 0 0 0 0 0 0 0 1467882 0 0 0 0 1106355 0 1342389 0 0 0 1056147 0 0 0 1068713 971126 0 0 1774651 0 1554952 0 828389 0 1401842 1638408 0 1180650 0 0 0 0 1644914 0 0 1447852 0 1020762 0 0 0 0 496373 0 597264 0 0 0 420822 0 0 0 460845 815066 0 0 1336284 0 336730 0 785776 0 423729 779302 0 1767767 0 0 0 0 617952 0 0 364815 0 320823 0 0 0 0 138360 0 0 0 0 0 214001 0 0 0 0 324853 0 0 0 0 0 0 0 0 289473 374649 0 0 0 0 0 0 276162 0 0 495117 0 -AADEKPDAPMISSVK MGYG000001338_03066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 1.0 2|Bacteria 1.0 S 1.0 peptidase inhibitor activity 1.0 - 1.0 - 1.0 3.4.24.40 1.0 ko:K01406 1.0 ko01503,map01503 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 1.0 1.0 1.0 1.0 Cationic antimicrobial peptide (CAMP) resistance 1.0 none 1.0 0 0 0 0 200628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248462 0 0 0 0 0 0 0 598751 314407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192039 0 0 0 0 79875 0 0 0 0 198236 0 0 0 98789 0 0 0 0 0 0 0 0 0 0 206353 0 0 0 0 0 0 0 0 0 0 0 0 228034 0 0 0 0 232488 0 0 0 0 176624 0 0 219485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1920021 0 0 0 0 0 0 0 0 0 0 0 0 1794890 0 0 0 0 1572928 0 0 0 0 1437353 0 0 2137253 1516444 0 0 0 0 0 0 -AADEKSAVK MGYG000001425_00725 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Tissierellales|f__Peptoniphilaceae|g__Peptoniphilus_A|s__Peptoniphilus_A senegalensis|m__MGYG000001425 1.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,22G0C@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family 1.0 lysS 1.0 - 1.0 6.1.1.6 1.0 ko:K04567 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03658 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DUF2156,tRNA-synt_2,tRNA-synt_2_TM,tRNA_anti-codon,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine--tRNA ligase. lysyl-tRNA synthetase. - ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9552044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADELGVTFT(Ethanolamine) MGYG000000133_00205 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3791559 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADELGVTY(Tyr->Phe)K MGYG000001338_00111;MGYG000000184_02413 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 313710 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 650818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245417 0 0 641337 0 0 0 0 0 0 0 0 0 0 131680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351878 0 0 0 0 500219 0 0 0 0 0 0 0 0 0 0 0 0 0 2937541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7445685 0 0 0 0 0 -AADELGVTYK MGYG000001338_00111;MGYG000000184_02413 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 3811508 5029408 4269913 2225909 4530492 4209259 1011235 4906524 0 4442304 6922828 4761381 4160235 3478235 5190356 6324270 0 6576264 4111698 5242324 3453310 5025167 3238237 1919312 5805657 2767715 2937925 5014401 3594927 3697307 1832318 3701815 2728665 3502364 3361207 2059270 2487762 3890142 0 11635603 1790701 3689940 2507843 0 0 5133836 2682124 1905752 0 1587187 0 2328646 2311363 2144616 3709714 6905630 2452602 4066628 2356084 1759864 4243528 0 2462822 2844296 3319438 7286606 3100275 2141082 8802901 0 2091281 4147822 3692229 0 2961799 2106214 2883040 7972833 2359843 3238579 1325059 2800078 1836174 3365366 1928645 3488887 3275345 3471393 2905945 2957719 3276684 4638748 3749660 1463106 2782310 2842317 2843169 4475583 2294147 2172917 3312199 2611670 3723495 2841045 2714533 4135779 3135173 3740827 0 2753220 2398301 1545373 2571783 3477527 2816763 10419306 1905419 3000471 5493421 1094407 3039839 2229881 2523263 3294534 3006162 3769553 2807535 2529021 2260367 4682596 6284163 2675127 1974229 3614023 2338918 3750351 945941 3948830 1992319 1589784 2813451 4211024 3789837 3091666 10195826 3748824 4386958 1016192 1749370 2147823 1815594 4627046 2676288 5259329 4786660 3002287 2086485 2036299 3864497 3785866 2284951 2393133 5435645 4788209 1693141 4505210 3375154 3922322 2983825 1669859 1988819 591415 3164013 4065454 3988377 3080865 2505907 2064965 3108651 5059820 3558321 681774 4147426 4625379 6962283 2961396 2389969 2813759 663297 4869947 -AADELKEYK MGYG000004869_04033 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lactonifactor|s__Lactonifactor sp009677585|m__MGYG000004869 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2552394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADENDALYVPTDNTVAANTGIVDGIC(Carbamidomethyl)RPAK MGYG000001300_00090 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3WHHG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01989 1.0 - 1.0 M00247 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 - 1.0 - 1.0 - 1.0 ABC_sub_bind,BPD_transp_2,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 391499 0 808666 0 0 0 483711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400834 408306 0 0 0 0 0 0 734991 0 0 0 530463 463796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225837 338298 0 0 0 0 0 0 399061 0 0 0 292018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1275480 0 1144652 0 0 0 2536510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1443215 1113720 0 0 0 0 0 0 969766 0 0 0 1331342 997928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADESKELFEGR MGYG000002494_01908 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0685@1|root,KOG0564@2759|Eukaryota 1.0 2759|Eukaryota 1.0 E 1.0 methylenetetrahydrofolate reductase (NAD(P)H) activity 1.0 MTHFR1 1.0 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.0 1.5.1.20,3.6.4.12 1.0 ko:K00297,ko:K10901 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko03440,ko03460,map00670,map00720,map01100,map01120,map01200,map01523,map03440,map03460 1.0 M00295,M00377,M00414 1.0 R01224,R07168 1.0 RC00081 1.0 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 1.0 - 1.0 - 1.0 - 1.0 BT1,DEAD,DUF1712,EamA,Helicase_C,Homoserine_dh,Hormone_recep,MTHFR,RecQ_Zn_bind,peroxidase,zf-C4 1.0 - 1.0 - 1.0 - 1.0 AA0 1.0 methylenetetrahydrofolate reductase [NAD(P)H]. | DNA helicase. MTHFR. A flavoprotein (FAD).-!-The enzyme catalyzes the reversible conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, playing an important role in folate metabolism by regulating the distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis.-!-This enzyme, characterized from Protozoan parasites of the genus Leishmania, is unique among similar characterized eukaryotic enzymes in that it lacks the C-terminal allosteric regulatory domain (allowing it to catalyze a reversible reaction) and uses NADH and NADPH with equal efficiency under physiological conditions. cf. EC 1.5.1.53, EC 1.5.1.54, and EC 1.5.7.1.-!-Formerly EC 1.1.1.68, EC 1.1.1.171, EC 1.1.99.15 and EC 1.7.99.5. | DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA.-!-Some of them unwind duplex DNA with a 3' to 5' polarity, other show 5' to 3' polarity or unwind DNA in both directions.-!-Some helicases unwind DNA as well as RNA.-!-May be identical with EC 3.6.4.13. (1) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH. (2) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH. | ATP + H2O = ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 Fanconi anemia pathway;Carbon metabolism;Homologous recombination;Carbon fixation pathways in prokaryotes;Metabolic pathways;Antifolate resistance;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1013324 0 0 1456336 877134 0 0 0 0 0 0 0 0 0 994905 0 0 0 0 1715203 0 1187248 0 0 0 0 1350444 671754 0 0 782137 0 0 0 0 736648 0 0 128725 0 0 101576 316782 0 0 0 0 0 0 0 0 0 77870 0 0 0 0 258909 0 0 0 0 0 0 140077 0 0 0 0 0 0 0 0 153839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 807794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADEVA(Ala->Gly)ALIDK MGYG000000171_00799;MGYG000000200_01407;MGYG000000184_00793;MGYG000000212_01426 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 0.5 186801|Clostridia 1.0 M 0.5 Cobalt chelatase (CbiK) 0.5 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 0.5 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1749538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4729488 0 0 0 0 7819581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADEVAALIDK MGYG000000171_00799;MGYG000000200_01407;MGYG000000184_00793;MGYG000000212_01426 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 0.5 186801|Clostridia 1.0 M 0.5 Cobalt chelatase (CbiK) 0.5 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 0.5 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 0 787708 795311 0 0 1318298 0 0 0 0 1076543 1697088 0 0 0 0 0 0 0 0 0 1560671 0 1355086 0 0 0 0 3983525 948171 0 0 668678 0 0 0 0 796930 0 276104 0 0 0 0 0 0 0 0 121866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3078177 0 0 0 0 0 0 0 0 0 0 0 389042 0 0 0 0 0 0 0 193138 744771 0 0 0 0 0 0 0 0 0 108403 0 214326 0 0 0 0 1369629 329246 0 0 656248 0 0 0 0 461544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12969929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385429 0 0 0 0 0 144152 0 0 0 0 0 0 0 0 0 317794 0 291581 0 0 0 0 0 0 0 0 0 0 0 0 0 343546 -AADEVGALIDK MGYG000001338_01847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,NAD_binding_7,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 1522172 5112060 1647834 954818 2823140 1295779 664490 1509521 0 1478779 3018332 1420004 1565123 1066641 1674633 1626183 1526269 2920457 1017607 1815743 0 1441751 2414988 567025 1900823 997947 983017 2911644 0 1126796 1443906 4582399 1300283 1252847 0 990173 948726 1527982 0 9345792 907830 0 1332268 1019062 0 0 0 927820 1358469 964840 1124246 997424 806383 740441 394857 10459618 1011488 0 0 872072 0 1492537 1249082 1095012 0 0 0 1145503 8575643 0 1001805 1476847 0 1392938 0 701688 1421661 10769992 1439378 1281347 826147 1047578 1042491 1425137 0 1343722 1491597 2886962 1311626 1180687 1766660 1686453 1130200 1110188 1308024 1329083 0 1551824 1696488 925824 1505159 1522223 1396128 0 1183682 3197702 2374748 8820223 2804102 1686482 0 942707 1343471 2063912 701022 11611271 1362497 890828 2478123 640010 1106599 754080 0 817894 1490455 1277190 1265610 750418 497051 1067693 949025 1865895 393973 715547 0 1019646 659856 1204454 652302 565827 678760 1941781 1103335 868469 7409221 5420999 1556064 655422 0 887863 943738 2398626 901514 14871264 4571871 1012289 1124653 672691 1512594 1532405 0 556308 1082454 1636571 989786 1505188 1249591 2358962 856238 2513435 740944 1078458 0 1309564 6251284 1441396 1078590 682720 868250 7471938 1299168 864876 6211592 6675522 6844177 1420338 0 684876 430649 3483475 -AADFANKVHAGEITNAAGEK MGYG000000262_02071 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,25VI8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 2.2.1.2,5.3.1.9 1.0 ko:K01810,ko:K13810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00004,M00007,M00114 1.0 R01827,R02739,R02740,R03321 1.0 RC00376,RC00439,RC00563,RC00604 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. | glucose-6-phosphate isomerase. glycerone transferase. | phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 292302 0 0 0 0 0 0 0 0 0 0 0 0 0 669983 0 359403 0 287389 0 0 0 0 0 0 0 0 0 203531 0 0 0 0 0 0 0 123797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 798047 0 581236 0 0 0 0 0 0 0 0 0 440248 0 0 802287 609547 0 795042 0 344392 0 0 0 0 0 0 0 0 0 959404 804479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADFASM(Oxidation)VVK MGYG000000802_01545;MGYG000000188_00827;MGYG000000333_00450;MGYG000004746_01526;MGYG000003274_01601;MGYG000002947_01134;MGYG000002978_00225;MGYG000002065_00755;MGYG000002970_00371;MGYG000001567_00996;MGYG000002775_01124 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0696@1|root,COG0696@2|Bacteria,2HHGK@201174|Actinobacteria,4CUJ8@84998|Coriobacteriia 0.9090909090909091 84998|Coriobacteriia 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 0.9090909090909091 gpmI 0.9090909090909091 - 1.0 5.4.2.12 0.9090909090909091 ko:K15633 0.9090909090909091 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 0.9090909090909091 M00001,M00002,M00003 1.0 R01518 0.9090909090909091 RC00536 0.9090909090909091 ko00000,ko00001,ko00002,ko01000 0.9090909090909091 - 1.0 - 1.0 - 1.0 Metalloenzyme,Phosphodiest,Sulfatase,iPGM_N 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 0.9090909090909091 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADFASMVVK MGYG000000802_01545;MGYG000000188_00827;MGYG000000333_00450;MGYG000004746_01526;MGYG000003274_01601;MGYG000002947_01134;MGYG000002978_00225;MGYG000002065_00755;MGYG000002970_00371;MGYG000001567_00996;MGYG000002775_01124 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0696@1|root,COG0696@2|Bacteria,2HHGK@201174|Actinobacteria,4CUJ8@84998|Coriobacteriia 0.9090909090909091 84998|Coriobacteriia 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 0.9090909090909091 gpmI 0.9090909090909091 - 1.0 5.4.2.12 0.9090909090909091 ko:K15633 0.9090909090909091 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 0.9090909090909091 M00001,M00002,M00003 1.0 R01518 0.9090909090909091 RC00536 0.9090909090909091 ko00000,ko00001,ko00002,ko01000 0.9090909090909091 - 1.0 - 1.0 - 1.0 Metalloenzyme,Phosphodiest,Sulfatase,iPGM_N 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 0.9090909090909091 none 1.0 0 2852228 0 439809 1020930 0 502393 0 645971 0 1398504 0 2503488 516287 0 2185835 693596 1519135 0 782380 0 0 1401375 0 0 0 289764 1499658 728598 346576 265534 0 0 0 0 0 0 0 0 441934 0 798600 716823 0 733432 0 458161 0 1331510 0 1008848 248094 0 575816 0 2146507 0 626616 0 0 1073492 0 0 0 476221 1917132 929214 1293431 1026687 0 0 0 0 0 0 0 0 839417 0 804848 0 0 450406 0 498108 0 375743 0 1475835 802094 0 1947278 1720262 338079 0 1161803 0 0 609992 0 0 0 1101890 1051827 1228984 1010272 0 0 0 0 0 0 0 0 0 1182144 0 1354539 2437931 0 898680 0 901189 0 3089946 0 4312945 1067673 0 0 1398484 790125 0 1458511 0 0 0 0 0 0 960577 1274707 2350451 1941604 1454421 0 0 0 0 0 0 0 0 348985 0 460507 0 0 625427 0 136738 0 602344 0 786703 363967 0 781938 174889 568825 0 0 0 0 520051 0 0 0 122598 806272 396753 170361 384901 0 0 0 0 0 0 0 -AADFDKQGR MGYG000002478_01470 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 1196767 0 1529162 747991 0 516312 0 0 1316147 0 1881435 813469 0 1423218 0 712590 0 0 872805 828535 1012764 1340667 0 0 976332 1070480 0 0 1247030 0 1128584 0 0 0 0 947878 0 0 682203 0 1186175 564068 0 551701 0 0 722481 0 2027317 855661 0 1212306 0 365380 0 0 638395 637607 854048 398210 0 0 770575 734929 0 0 491390 0 495863 0 0 0 0 411063 0 0 483322 0 660132 429958 0 272119 0 0 397845 0 978046 404572 0 774179 0 304216 0 0 372572 363604 410757 421302 0 0 343053 490893 0 0 560149 0 297470 0 0 0 0 376977 0 0 588515 0 249853 810353 0 197529 0 0 587303 0 247255 161951 0 382606 0 457569 0 0 0 1032449 307804 888309 0 0 99226 6605 0 0 303848 0 612097 0 0 0 0 838664 0 0 549729 0 1216977 716738 0 510826 0 0 769111 0 2589715 420850 0 1245682 0 749824 0 0 332914 577510 797273 629552 0 0 560858 331794 0 0 891889 0 428860 0 0 0 0 839206 -AADFEK MGYG000002065_00816;MGYG000003266_01415;MGYG000001642_00536;MGYG000004681_00135 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CURX@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 alcohol dehydrogenase 1.0 adh1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 2528803 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1334038 0 490324 0 0 577588 0 0 0 0 60646 0 0 0 0 0 0 0 0 0 0 0 150545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338474 0 160296 0 0 70063 0 0 0 0 4750630 0 0 0 0 0 0 0 0 0 0 0 474727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10813 0 201233 0 0 219280 0 0 0 0 449394 0 0 0 0 0 0 0 0 0 0 0 1631110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1167331 0 765203 0 0 161256 0 0 0 0 1306790 0 0 0 0 0 0 0 0 0 0 0 170294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 509801 0 345545 0 0 720071 0 0 0 0 422801 0 0 0 0 0 0 0 0 0 0 -AADFEKILK MGYG000002970_01542;MGYG000002947_01395;MGYG000003266_01415;MGYG000000188_01843;MGYG000001642_00536;MGYG000004681_00135 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CURX@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 alcohol dehydrogenase 1.0 adh1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADFIMENVKER MGYG000000280_00174 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__AM51-8|s__AM51-8 sp003478275|m__MGYG000000280 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,27I7R@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1889768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADFLAIGK MGYG000001302.1_01195 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia,22UAZ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 544372 0 0 0 0 414272 0 0 0 0 442272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88681 0 0 0 0 216862 0 0 0 0 278856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2225057 0 0 0 0 3371266 0 0 0 0 1913907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179751 0 0 0 0 94258 0 0 0 0 454150 0 0 0 0 0 0 0 0 0 0 -AADFLDGIK MGYG000000224_00483;MGYG000000442_01373;MGYG000000054_03942;MGYG000000196_03983;MGYG000002549_02931;MGYG000002455_03893;MGYG000004763_01698;MGYG000002291_02263;MGYG000001378_05033;MGYG000001345_04693;MGYG000001346_01525 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 1133246 785984 542527 1161275 703311 766599 1370099 1011998 1211934 1039546 2225667 1239850 582305 1026204 1224772 1057306 915557 319236 909755 899580 866380 832687 368261 1121270 955615 1237706 671051 0 761129 1257994 927169 255872 674226 1326107 800946 1207038 813918 618770 1304648 611915 1267610 1490019 851597 1164892 870411 1362729 1370960 1739162 2466392 1721911 847440 1550843 1585498 1101784 1104600 104163 1070873 1119073 1238045 1107127 299895 905450 1257676 1438560 1253682 187702 925321 1089921 815186 1072684 1199152 1101036 1232998 1315440 1443836 1058483 1088361 779110 1241389 876939 1165298 911407 1179716 916474 1018453 681578 2170284 1264441 859776 1002659 650781 945347 825129 1184692 682965 893406 902676 711746 975894 983521 871539 1010161 861186 747581 1011177 1089049 1048498 740603 838457 605099 811115 1156378 1026163 1140218 1408003 1123504 1269002 1235636 1369888 1293364 1271402 1407500 1430446 1513345 1763925 1695261 1518506 1463532 1623515 1554133 1422933 1183439 1187053 1320999 1403377 1069109 1255238 1155718 1302420 1449260 1245101 1006723 1207540 1386164 1395563 1378450 1351172 1377627 1649184 1550313 1461031 1116213 739087 440107 505109 672214 1181366 1221971 836865 1047343 1102655 720463 1829447 867242 1024753 463408 724406 985737 800276 1397539 591481 1183122 526627 1174053 955154 1144340 1029024 679618 647456 738621 626678 1212503 651744 672189 286914 1076497 963331 460376 181811 628824 -AADFNALPTWK MGYG000000223_03085 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0205@1|root,COG0205@2|Bacteria,1UN7X@1239|Firmicutes,3VNZJ@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 G 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1272207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1888746 3906876 0 0 0 0 0 0 0 0 0 301376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 905040 2247551 0 0 0 0 0 0 0 0 0 749346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADFSAIVNFK MGYG000004717_01610 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Megamonas|s__Megamonas hypermegale|m__MGYG000004717 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4H27A@909932|Negativicutes 1.0 909932|Negativicutes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 266190 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633722 0 0 0 0 1217768 0 0 0 0 589694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADGAIAATQAEK MGYG000001315_00850 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,27IZT@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Pyridine nucleotide-disulphide oxidoreductase 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106206 0 0 0 0 263148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220990 0 0 529421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604590 0 0 0 0 863679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADGEYR MGYG000000133_00908;MGYG000002517_02577;MGYG000000139_02038 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,3Y05I@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 D 1.0 Could be involved in septation 1.0 spoVG 1.0 - 1.0 - 1.0 ko:K06412 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 SpoVG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 257807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 717168 0 0 0 0 0 0 0 0 57664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72706 0 0 0 0 0 0 0 0 333676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 494039 0 0 0 0 0 0 0 0 788799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADGEYRDIAHPINSNTR MGYG000004271_00115 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 Could be involved in septation 1.0 spoVG 1.0 - 1.0 - 1.0 ko:K06412 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 SpoVG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADGKTDLYYR MGYG000000243_01558 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1506@1|root,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,2FMJD@200643|Bacteroidia,4ANDK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase, S9A B C family, catalytic domain protein 1.0 pepX2 1.0 - 1.0 3.4.14.5 1.0 ko:K01278 1.0 ko04974,map04974 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 1.0 - 1.0 - 1.0 - 1.0 DPPIV_N,Peptidase_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 dipeptidyl-peptidase IV. Xaa-Pro-dipeptidylaminopeptidase. A membrane-bound serine-type peptidase in mammals.-!-EC 3.4.14.11 catalyzes a similar reaction.-!-Belongs to peptidase family S9B. Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline. 1.0 1.0 1.0 1.0 Protein digestion and absorption 1.0 none 1.0 0 0 531380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 634150 0 0 0 0 675097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253306 0 0 282136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147133 0 0 0 0 224213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189605 0 0 0 0 0 0 0 80933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265937 -AADGNNFGTVLIPEGLIEFIPAIKK MGYG000003697_01061 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7321280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADGPMPQTR MGYG000003185_01053;MGYG000003185_01074;MGYG000003142_01865;MGYG000004804_00945;MGYG000003142_01879;MGYG000000143_00646;MGYG000002994_01317;MGYG000000445_01370;MGYG000000258_00266;MGYG000004769_00412;MGYG000003236_02455;MGYG000004769_00437;MGYG000004717_00227;MGYG000001646_01118;MGYG000001749_02490;MGYG000001412_04734;MGYG000001470_03722;MGYG000004804_01395;MGYG000001712_00119;MGYG000001485_02164;MGYG000001464_00103;MGYG000001508_00032;MGYG000001431_01181 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4H22P@909932|Negativicutes 0.2608695652173913 91061|Bacilli 0.2608695652173913 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.6521739130434783 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.7391304347826086 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 507910 0 0 259807 0 0 0 0 319971 0 0 0 0 361146 184187 860142 0 0 0 373686 288590 145063 0 0 0 545393 200858 0 236933 0 273425 0 0 0 0 307203 0 0 1061459 0 0 1018135 0 0 0 0 997096 0 0 0 0 794634 675208 355968 0 0 0 936318 0 933392 0 0 0 389409 587832 0 760697 0 914942 0 0 0 0 965071 0 0 337787 0 0 438991 0 0 0 0 341315 0 0 0 0 649763 319125 0 0 0 0 290287 0 140826 0 0 0 259213 438450 0 0 0 424124 0 0 0 0 461739 0 0 2076410 0 0 2416262 0 0 0 0 1837483 0 0 0 0 2138221 2121777 4097543 0 0 0 3360707 1427662 4682262 0 0 0 9208287 3053908 0 2706121 0 2858183 0 0 0 0 2910238 0 0 284669 0 0 857279 0 0 0 0 1008931 0 0 0 0 555395 414475 725718 0 0 0 957744 635110 926402 0 0 0 500198 1050424 0 873522 0 581328 0 0 0 0 1102131 -AADGTAQYYTK MGYG000002470_04263;MGYG000004899_00606 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FN3Y@200643|Bacteroidia,4AP89@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 389920 0 0 0 0 0 0 0 0 0 581791 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADGTVTGVK MGYG000003694_02659 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter faecis|m__MGYG000003694 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 269035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480642 0 0 0 0 449134 0 0 0 0 183589 0 0 0 0 0 0 0 0 0 286483 0 0 1117676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1395413 0 0 0 0 619741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220835 0 0 0 0 833434 0 0 0 0 407863 0 0 0 0 0 0 0 0 0 0 0 0 10098177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21973411 0 0 0 0 9228879 0 0 0 0 17611767 0 0 0 0 0 0 0 0 0 18268293 0 0 457393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447421 0 0 0 0 286794 0 0 0 0 330308 0 0 0 0 391752 0 0 0 0 945012 -AADGVILITTK MGYG000000174_03825 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides faecis|m__MGYG000000174 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1729921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1998101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADGVILVTTK MGYG000001489_00895 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides goldsteinii|m__MGYG000001489 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 592497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5470540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADGVIYITTK MGYG000004763_02544 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG4206@1|root,COG4206@2|Bacteria,4PMK4@976|Bacteroidetes,2G0EG@200643|Bacteroidia,4AMPZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1552021 0 0 0 0 1848543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADGVIYITTKR MGYG000004763_02544 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG4206@1|root,COG4206@2|Bacteria,4PMK4@976|Bacteroidetes,2G0EG@200643|Bacteroidia,4AMPZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1884661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADGVQPQSETVWR MGYG000002293_00507 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 309293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332079 0 0 0 0 0 0 0 3173356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2293382 0 0 0 0 3700073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADGVVIITTK MGYG000003363_02494 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900766195|m__MGYG000003363 1.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKGC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1827242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1980547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADGYTYYMAEALLDKVLGR MGYG000002517_00846 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) 1.0 ileS 1.0 - 1.0 6.1.1.5 1.0 ko:K01870 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03656 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 isoleucine--tRNA ligase. isoleucyl-tRNA synthetase. - ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 355979 0 0 0 272121 0 0 0 310640 0 0 0 0 248580 0 0 0 0 0 0 0 0 0 0 0 371845 0 0 0 0 0 0 0 0 0 0 0 0 144517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219496 0 0 0 0 0 0 0 0 0 0 15062972 0 5274094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6398376 0 0 0 0 0 0 0 0 0 0 6324442 0 52447160 0 0 0 29761596 0 0 0 19309779 0 0 0 0 90933781 0 0 0 0 0 0 0 0 0 0 0 49283808 0 0 0 0 0 0 0 0 0 0 72995057 0 -AADHAHAAQKPEAVEI MGYG000003921_00100 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3WIWI@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly 1.0 rplM 1.0 - 1.0 - 1.0 ko:K02871 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390722 0 0 0 0 441953 0 0 0 0 246370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690527 0 0 0 0 465797 0 0 0 0 597931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 554732 0 0 0 0 438915 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209113 0 0 0 0 487591 0 0 0 0 149680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 142251 0 0 0 0 596116 0 0 0 0 2255491 0 0 0 0 0 0 0 0 0 0 -AADIAAIGITNQR MGYG000002934_02584;MGYG000000164_01754;MGYG000002274_01022;MGYG000001496_03285;MGYG000002993_00205;MGYG000003819_01517;MGYG000000404_00178;MGYG000000370_01160;MGYG000002517_00523;MGYG000002105_01106;MGYG000002212_02389 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 0.36363636363636365 186801|Clostridia 0.9090909090909091 F 0.5454545454545454 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 1175684 0 785287 0 1474421 0 1133954 1698226 1397368 1884138 0 0 1364960 1331877 2481302 1001621 834979 0 1679718 1525442 0 0 0 0 1893058 1399771 0 0 0 0 0 0 509618 1290736 1281356 0 1038632 627724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 142648 0 0 240605 0 0 0 0 0 187489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADIADIR MGYG000002970_01267;MGYG000002065_00912;MGYG000004746_00558;MGYG000003266_00145;MGYG000000188_00405;MGYG000003122_01006;MGYG000004681_00319;MGYG000002947_01668;MGYG000000802_00031;MGYG000000333_01777;MGYG000001718_01732;MGYG000004875_01408 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CV00@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9 1.0 ko:K08483 1.0 ko02060,map02060 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--protein phosphotransferase. sugar--PEP phosphotransferase enzyme I. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 none 1.0 0 2807089 453817 0 0 0 0 0 0 0 764196 0 1285095 228177 0 1486288 154394 0 0 708832 0 0 0 0 0 0 0 0 0 208475 0 0 223427 0 0 0 0 477001 0 656486 211977 0 0 0 0 0 0 0 870576 0 751837 213300 0 634879 210812 0 0 512954 0 0 0 0 0 0 0 0 0 488179 0 0 210760 0 0 0 0 470915 0 0 0 0 0 0 0 0 0 0 224709 0 1059741 0 0 1398347 1030179 0 0 1040297 0 0 0 0 0 0 0 0 0 736789 0 0 1053415 0 0 0 0 0 0 1148988 900497 0 0 0 0 0 0 0 2785309 0 2985280 1019367 0 4475312 1891721 0 0 1287500 0 0 0 0 0 0 0 0 0 1858283 0 0 1021966 0 0 0 0 1085699 0 186201 571957 0 0 0 0 0 0 0 550282 0 577334 472228 0 822705 360419 0 0 274118 0 0 0 0 0 0 0 0 0 247538 0 0 439520 0 0 0 0 323475 -AADIAGIGITNQR MGYG000000077_01442;MGYG000000262_02304 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,25VA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 F 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1023511 0 0 1087615 0 0 0 0 0 0 0 0 0 2522430 1894680 0 0 1864358 0 1455264 0 1263158 0 0 967063 0 2269924 0 0 0 1578186 0 0 0 0 1642335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADIEGFLAEESKAEAGK MGYG000002528_02847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053043 0 0 0 0 514370 0 0 0 0 808413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADIGAIGITNQR MGYG000000489_01562;MGYG000002517_00259;MGYG000000389_02030 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 78022 0 0 0 635186 0 0 726293 0 732755 0 0 0 684494 949237 0 0 0 913529 599747 0 0 0 70490 901342 670112 376952 0 89227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92517 116724 0 0 0 0 0 0 0 0 0 107664 0 0 0 0 57950 0 0 0 0 0 156498 0 0 74198 0 0 0 0 0 0 0 403233 0 5970692 0 0 6414354 3712055 2779985 4605336 6667728 9678135 3751584 0 2402751 0 7031006 6845773 0 6812413 0 9127343 9245314 2898930 1237498 0 1549616 3530144 4436494 6554872 0 3297228 3698060 2206825 0 0 2377678 5163410 4337423 6376983 0 0 0 0 0 0 93666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 96094 0 0 0 0 0 0 0 -AADIIR MGYG000000074_02400;MGYG000000098_00813;MGYG000000196_04138 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,4AN6T@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 COG2086 Electron transfer flavoprotein beta subunit 0.6666666666666666 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 403264 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 349946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADIKDVTYR MGYG000000223_00596 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,3VNU4@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9 1.0 ko:K08483 1.0 ko02060,map02060 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--protein phosphotransferase. sugar--PEP phosphotransferase enzyme I. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178745 0 0 0 0 0 0 0 0 686315 0 0 0 0 0 0 0 0 0 218036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 737845 0 0 0 0 0 0 0 0 1481048 0 0 0 0 0 0 0 0 0 576330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92631 0 0 0 0 0 0 0 0 -AADILAQEGISVR MGYG000004828_01159;MGYG000002485_00028 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG3958@1|root,COG3958@2|Bacteria,378ZW@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 883370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADILEK MGYG000004271_01895;MGYG000002517_00838;MGYG000000271_01394;MGYG000001615_03000;MGYG000003335_02805;MGYG000004431_00578;MGYG000001065_02180;MGYG000001338_00069;MGYG000000389_01232;MGYG000004719_01604;MGYG000002247_02694 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia 0.6363636363636364 186801|Clostridia 1.0 F 0.6363636363636364 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) 0.6363636363636364 purE 0.6363636363636364 - 1.0 5.4.99.18 0.6363636363636364 ko:K01588 0.6363636363636364 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 0.6363636363636364 M00048 0.6363636363636364 R07405 0.6363636363636364 RC01947 0.6363636363636364 ko00000,ko00001,ko00002,ko01000 0.6363636363636364 - 1.0 - 1.0 - 1.0 AIRC 0.6363636363636364 - 1.0 - 1.0 - 1.0 - 1.0 5-(carboxyamino)imidazole ribonucleotide mutase. N(5)-carboxyaminoimidazole ribonucleotide mutase. In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates.-!-In the absence of EC 6.3.2.6, the reaction is reversible.-!-The substrate is readily converted into 5-amino-1-(5-phospho-D- ribosyl)imidazole by non-enzymic decarboxylation. 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1- (5-phospho-D-ribosyl)imidazole-4-carboxylate. 0.6363636363636364 0.6363636363636364 0.6363636363636364 0.6363636363636364 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 0.6363636363636364 none 1.0 1052598 1199702 723830 5349792 4029791 812757 0 0 0 1157059 1755274 3489029 1245699 1027766 0 0 884279 0 1157733 1130215 1584168 1273593 0 974324 1168062 677139 0 0 0 0 773411 915075 802269 440683 0 0 1130951 765208 0 1391545 215763 0 749097 451310 0 0 0 0 432089 0 538345 282079 0 0 0 0 0 410949 318604 0 0 0 0 239321 0 0 0 0 1671528 721728 567053 0 0 0 394344 246181 436775 1684644 669411 474294 0 413877 0 0 0 609014 233514 423459 583214 284920 0 0 473712 0 479087 0 0 620542 0 0 417831 519080 0 0 0 0 403434 1274028 717847 765558 0 0 0 303899 2155653 2170547 1032396 2122280 1995714 1153801 0 0 0 1405632 1091446 688763 1205818 2286761 0 0 1184248 0 653285 2116874 957577 629228 0 624730 0 1679680 0 0 0 0 2170603 2690160 1077470 1170437 0 0 819162 1230671 0 3413739 2961115 973064 1818772 0 0 0 0 3055546 2263886 2022411 2398451 3614099 0 0 2496541 0 2362114 2089263 2198337 2854316 0 2522986 2893736 2523812 0 0 0 0 2598067 2527883 3766700 2662621 0 0 2670037 0 -AADILR MGYG000000074_02400;MGYG000002549_02817;MGYG000001496_01438;MGYG000000133_02450;MGYG000000196_04138;MGYG000001337_03724;MGYG000001345_00398;MGYG000001315_02145 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,4AN6T@815|Bacteroidaceae 0.5 976|Bacteroidetes 0.625 C 1.0 COG2086 Electron transfer flavoprotein beta subunit 0.5 etfB 0.625 - 1.0 - 0.625 ko:K03521 0.625 - 0.625 - 0.625 - 0.625 - 0.625 ko00000 0.625 - 1.0 - 1.0 - 1.0 ETF 0.625 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.625 0.625 0.625 0.625 0.625 none 1.0 1160859 0 0 1214029 0 0 0 1002951 0 1396401 1612161 0 0 2011343 0 0 0 1098444 0 0 0 0 888884 0 1247193 1390000 0 0 0 0 0 0 0 0 0 0 1551333 0 1692057 0 0 1279700 0 0 0 1566196 0 1509417 1578161 0 0 1340129 0 0 0 0 0 0 0 0 563081 0 1422606 1519075 0 2206049 0 0 0 0 0 0 0 0 1497229 0 1045197 0 0 1251470 0 0 0 1253772 0 1173292 1526128 0 0 1344549 0 0 0 0 0 0 0 0 1194226 0 1257262 1408416 0 859115 0 0 0 0 0 0 0 0 1193027 0 1470679 0 0 1701098 0 0 0 0 0 2997120 1481902 0 0 1683966 0 0 0 0 0 0 0 0 672487 0 1026148 1145734 0 1261508 0 0 0 0 0 0 0 0 1965915 0 2659743 0 0 3018195 0 0 0 2274079 0 0 1755100 0 0 1455068 0 0 0 621724 0 0 0 0 792005 0 2719961 3661296 0 854106 0 0 0 0 0 0 0 0 3488781 0 -AADIM(Oxidation)K MGYG000001770_02443;MGYG000003697_02383;MGYG000004797_03938;MGYG000001789_01650;MGYG000000325_00235;MGYG000002478_03963;MGYG000002293_02246;MGYG000003486_01435;MGYG000000781_01961;MGYG000001306_02131;MGYG000000243_01707 domain d__Bacteria 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 0.5454545454545454 976|Bacteroidetes 0.8181818181818182 EF 0.5454545454545454 COG0462 Phosphoribosylpyrophosphate synthetase 0.5454545454545454 prs 0.8181818181818182 - 1.0 2.7.6.1 0.8181818181818182 ko:K00948 0.8181818181818182 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 0.8181818181818182 M00005 0.8181818181818182 R01049 0.8181818181818182 RC00002,RC00078 0.8181818181818182 ko00000,ko00001,ko00002,ko01000 0.8181818181818182 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 0.8181818181818182 - 1.0 - 1.0 - 1.0 - 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 0.8181818181818182 0.8181818181818182 0.8181818181818182 0.8181818181818182 Pentose phosphate pathway;Carbon metabolism;Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 0.8181818181818182 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADIMK MGYG000001770_02443;MGYG000003697_02383;MGYG000004797_03938;MGYG000001789_01650;MGYG000000325_00235;MGYG000002478_03963;MGYG000002293_02246;MGYG000003486_01435;MGYG000000781_01961;MGYG000001306_02131;MGYG000000243_01707 domain d__Bacteria 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 0.5454545454545454 976|Bacteroidetes 0.8181818181818182 EF 0.5454545454545454 COG0462 Phosphoribosylpyrophosphate synthetase 0.5454545454545454 prs 0.8181818181818182 - 1.0 2.7.6.1 0.8181818181818182 ko:K00948 0.8181818181818182 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 0.8181818181818182 M00005 0.8181818181818182 R01049 0.8181818181818182 RC00002,RC00078 0.8181818181818182 ko00000,ko00001,ko00002,ko01000 0.8181818181818182 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 0.8181818181818182 - 1.0 - 1.0 - 1.0 - 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 0.8181818181818182 0.8181818181818182 0.8181818181818182 0.8181818181818182 Pentose phosphate pathway;Carbon metabolism;Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 0.8181818181818182 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 1258122 0 0 1025106 1447603 1108225 0 0 0 1604717 0 0 0 0 1936183 0 0 2599782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520783 0 0 1056517 1002250 1078035 0 0 0 2454965 0 0 0 0 878832 0 0 1118277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 747560 0 0 998133 0 1740510 0 0 0 883947 0 0 0 0 1350394 0 0 370571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184270 0 0 1126733 2608826 952502 0 0 0 911635 0 0 0 0 2327058 0 0 1496354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1400334 0 0 704015 1588680 601928 0 0 0 1235624 0 0 0 0 1219572 0 0 665934 0 0 0 0 0 0 0 -AADIMKEAGAISVR MGYG000004797_03938;MGYG000002478_03963;MGYG000000243_01707 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EF 1.0 COG0462 Phosphoribosylpyrophosphate synthetase 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADIQAYEIGLTDSK MGYG000002549_02730 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG1196@1|root,COG1196@2|Bacteria,4P0K9@976|Bacteroidetes,2FRA0@200643|Bacteroidia,4APBZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 D 1.0 domain, Protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 722102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 482544 0 0 0 0 0 0 0 0 0 0 0 0 0 439691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318005 0 0 0 585706 0 0 0 0 0 0 0 0 0 628355 0 0 0 201323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 539622 0 0 0 0 0 0 0 0 0 308443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475135 0 0 0 419367 0 0 0 0 0 0 0 0 0 2817623 0 0 0 5824380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2260257 0 0 0 2940817 0 0 0 -AADISNAIR MGYG000003166_02092;MGYG000000195_02922;MGYG000002619_00241;MGYG000000022_00970 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WH0G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 NADH oxidase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Oxidored_FMN,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1638656 0 0 0 0 2764761 0 0 0 0 2873694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1317970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADIVLQAAIAAGAPK MGYG000002323_02346;MGYG000000093_03243;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206;MGYG000002534_02768;MGYG000003883_03730 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.8571428571428571 1236|Gammaproteobacteria 1.0 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.8571428571428571 adhE 1.0 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 786180 836035 1437175 764368 541165 3384587 1560598 1211494 987934 1297778 410887 886948 278075 870496 620041 279249 720298 0 762814 738507 838926 3801177 0 3836238 913609 656919 770472 0 1454703 1051912 910012 661074 1141067 1040819 1095762 655736 812870 1209052 14574500 18237010 16650843 16498192 24485860 29752006 21226548 12985771 16317291 0 6251523 14799347 10112658 19630833 18926503 14485198 28562668 0 22761992 18020488 22786335 43165826 0 28289069 21595215 0 14145626 0 27620421 17964922 9470720 11737287 18622860 14874758 11922539 12635696 11580882 17451290 997866 1121862 1447396 965338 1003727 4856953 1233329 1283765 657110 1243409 836022 840228 1071516 963971 808170 1119930 962507 0 984475 971760 996931 3934001 0 4487220 1006441 816464 1139894 0 792465 914043 1005576 824517 2576234 1692580 1181064 1049658 695323 1714242 1662086 530753 1233237 1093474 604906 1976158 1787559 1509527 934784 825253 346688 698691 907360 995955 897148 740256 576045 0 1050753 939122 2040431 1797811 0 755813 1630100 1512165 1557393 0 539901 1039367 175798 728721 971255 2820489 2498169 1695267 980150 561074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADIVLQAAIAAGAPK(Cation_Na) MGYG000002323_02346;MGYG000000093_03243;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206;MGYG000002534_02768;MGYG000003883_03730 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.8571428571428571 1236|Gammaproteobacteria 1.0 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.8571428571428571 adhE 1.0 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 204046 0 0 297570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319864 0 264226 0 0 0 0 0 0 0 0 110654 0 0 0 0 221198 0 0 908323 0 0 1114280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1555182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238944 0 0 0 0 335071 0 0 77887 0 0 314067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163460 0 79545 0 0 0 0 0 0 0 0 62983 0 0 0 0 101030 0 0 0 0 0 316982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203230 -AADK(Lys->Gln)PFLMPVEDVMTISGR MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1182821 0 0 0 0 0 948013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADKDATVLAAVSAIDK MGYG000002274_02947;MGYG000004679_00122;MGYG000000022_01840 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3WKKU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADKEGAPMK MGYG000002517_03263 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit 1.0 rpsR 1.0 - 1.0 - 1.0 ko:K02963 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S18 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 62134 0 0 0 0 0 0 100415 0 0 0 0 0 0 0 0 0 0 0 196439 0 0 0 0 0 0 66247 0 0 0 0 0 0 0 0 0 0 109058 24241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100203 0 0 0 42823 103443 0 0 0 0 0 0 0 0 0 88691 0 0 0 46919 0 0 0 0 0 40751 0 0 0 0 94776 81712 89049 0 0 0 0 0 0 0 0 81454 0 0 495934 0 46162 0 0 0 0 389430 744270 148681 0 0 0 242619 0 0 0 0 0 426363 0 0 0 0 541326 592607 636251 0 0 0 0 0 1579246 0 0 98058 470793 88034 168716 0 581079 0 0 0 0 266549 373760 666782 0 0 0 710948 0 0 0 0 0 129070 0 0 0 0 397760 360058 843497 0 0 0 0 0 663868 0 0 554623 463520 495773 -AADKEGAPMKR MGYG000002517_03263 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit 1.0 rpsR 1.0 - 1.0 - 1.0 ko:K02963 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S18 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 141560 81804 0 165412 36734 78691 0 80561 150578 130682 51839 71579 0 52732 269444 193931 185960 0 0 337306 0 131764 0 0 203982 198303 169706 0 0 77118 0 0 0 0 85634 159881 196029 51098 45379 0 0 0 0 0 0 0 0 0 96432 0 0 53362 0 0 0 0 0 0 0 0 0 0 51928 56991 0 0 0 0 0 0 0 0 0 23899 0 0 50603 69418 46576 57117 0 0 0 47467 65048 0 0 31370 0 0 114303 49034 0 0 0 67150 0 73622 0 0 0 0 87300 0 0 29157 0 0 138753 0 138315 38598 138907 0 1448809 410281 251051 1900977 724554 314005 0 1453171 2593187 464082 623350 607908 0 1501109 544144 740185 1381617 0 0 1467290 0 314703 0 0 1392005 1937698 1803390 0 0 956504 0 532264 124949 0 1920764 471062 2926840 225607 1351591 1364328 1928043 106732 373955 850103 0 1034558 1464609 4812096 1526136 1759671 0 2506619 1838363 1069043 1156753 0 0 769638 0 1062635 0 1169448 2017326 1385846 2005260 0 0 525515 0 268930 2556904 0 2307691 2065405 1848759 1391402 -AADKFPQAQLVLSAK MGYG000000271_00867;MGYG000004271_01998 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Desulfoferrod_N,Desulfoferrodox,Flavodoxin_1,Flavodoxin_5,Lactamase_B,Lactamase_B_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADKPFLM(Oxidation)PVEDVM(Oxidation)TISGR MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 590645 0 0 0 0 317657 0 0 0 0 321100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 108801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312105 0 0 0 0 509311 0 0 0 0 289642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384857 0 0 0 0 476864 0 0 0 0 142781 0 0 0 0 0 0 0 0 0 0 -AADKPFLM(Oxidation)PVEDVMTISGR MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 444411 0 0 1079560 387216 0 0 0 0 745346 456147 0 0 1830942 0 1647801 1456915 0 490419 0 475543 460845 201150 0 0 0 786035 0 423877 0 1426844 0 0 0 0 0 0 0 193298 0 0 299930 261918 0 0 0 0 257593 690767 0 0 373356 0 391392 507935 0 322272 0 177129 608318 256752 0 0 0 376598 0 362531 0 256053 0 0 0 0 0 0 0 165993 0 0 649141 0 0 0 0 0 614220 395405 0 0 110867 0 0 496519 0 422357 0 0 478601 0 0 0 0 155331 0 290301 0 143360 0 0 0 0 0 0 0 94353 0 0 161940 146555 0 0 0 0 103735 388282 0 0 77413 0 53193 325049 0 110691 0 87467 333606 470340 0 0 0 336877 0 225054 0 153828 0 0 0 0 0 0 0 0 0 0 74702 175942 0 0 0 0 0 3533196 0 0 0 0 2832444 1738338 0 112576 0 99274 1252815 0 0 0 0 212391 0 70219 0 0 0 0 0 0 0 0 -AADKPFLMPV(Val->Xle)EDVMTISGR MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1277330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADKPFLMPVEDVM(Oxidation)TISGR MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 610533 529730 0 0 559430 509736 0 836993 0 610584 0 913804 681125 0 881418 857187 1091712 1654030 0 706529 0 812727 729700 207933 619791 415473 0 930605 0 0 0 0 0 0 519236 0 355269 0 145967 337637 0 0 341165 0 0 696112 0 0 0 836735 309929 0 0 298385 0 444848 0 0 0 0 475446 290436 520939 276264 0 386426 0 0 0 0 0 0 520224 0 0 0 238228 312098 0 0 361517 138200 0 259694 0 0 0 492382 189859 0 593798 480908 734417 148007 0 705524 0 211674 310543 217630 445327 254998 0 231048 0 0 0 0 0 0 194666 0 289546 0 247080 282141 0 0 373764 0 0 417482 0 253517 0 724930 216266 0 277055 335424 227221 430991 0 174809 0 287854 551523 319690 395625 116287 0 590092 0 0 0 0 0 0 378842 0 90181 0 256831 419225 0 0 554146 334276 0 225998 0 281960 0 977477 172116 0 515011 411553 254739 901808 0 443994 0 361052 849636 341930 282181 173764 0 1067906 0 0 0 0 0 0 159448 0 136159 0 -AADKPFLMPVEDVMTISGR MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 17024164 0 396771 0 15413968 4319821 0 34151797 13448446 0 0 30840136 0 0 141412 0 0 11245888 0 0 0 13222267 1695463 14440753 0 183965 0 2587934 0 0 0 0 14524912 0 15407314 0 300792 113355 44258 0 3399067 0 198745 157492 0 8399862 320665 0 0 2141768 0 0 297764 0 0 21143704 0 0 0 284276 22096635 484136 0 311731 0 15432613 0 0 0 0 1695998 0 190812 0 4922386 194212 615868 0 4020668 0 4061390 218382 0 5230400 5482537 0 0 183158 0 0 4689346 0 0 6599348 0 0 0 1361728 958184 270873 0 176569 0 7980301 0 0 0 0 308926 0 3910680 0 760619 425592 184304 0 6013929 0 4747512 8612803 0 920296 5729981 0 0 25164607 0 0 9029495 0 0 318300 0 0 0 273991 1607319 3850050 0 880844 0 21492563 0 0 0 0 9467975 0 347186 0 81421 2309258 1929557 0 0 0 17867280 202920 0 0 5789558 0 0 12788628 0 0 0 0 0 30956500 0 0 0 266355 42279158 171733 0 0 0 44198908 0 0 0 0 17052789 0 1270230 0 172719 0 -AADLAAK MGYG000000074_01219 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,2FPGP@200643|Bacteroidia,22U60@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Zinc ribbon domain 1.0 - 1.0 - 1.0 - 1.0 ko:K07164 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 zf-RING_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1523670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLAGR MGYG000001302.1_01989 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,22U24@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 605037 0 0 350438 0 0 0 0 736242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 621029 0 0 0 0 345186 0 0 0 0 227040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLDAIHDTVHEM(Oxidation)AKDEAR MGYG000000171_01528 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 266841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 776631 0 0 0 98283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLDAIHDTVHEMAKDEAR MGYG000000171_01528 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 908154 0 0 0 0 970225 0 261089 0 219345 1009298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380954 0 0 0 0 106988 0 0 0 168076 236966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102905 0 0 0 0 281731 0 363991 0 365671 374821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151840 0 0 0 0 0 0 0 0 0 502215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLDTANVLR MGYG000001300_00560;MGYG000002223_01031 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3WGKI@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 citrate synthase 1.0 gltA2 1.0 - 1.0 2.3.3.1 1.0 ko:K01647 1.0 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 1.0 M00009,M00010,M00012,M00740 1.0 R00351 1.0 RC00004,RC00067 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Citrate_synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 citrate (Si)-synthase. citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA]. The stereospecificity of this enzyme is opposite to that of EC 2.3.3.3, which is found in some anaerobes.-!-Citrate synthase for which the stereospecificity with respect to C2 of oxaloacetate has not been established are included in EC 2.3.3.16.-!-Formerly EC 4.1.3.7. acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+). 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Citrate cycle (TCA cycle);Glyoxylate and dicarboxylate metabolism;Carbon metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 672681 0 479838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 693829 0 0 0 0 0 609709 0 0 0 0 0 0 0 0 0 0 0 0 0 1515002 1260948 0 1804187 0 0 0 0 0 0 0 983438 0 0 0 0 0 0 1381615 1503396 0 0 0 0 1507297 1347402 0 0 0 0 0 0 0 0 0 0 1545715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690549 1227308 0 958165 0 0 0 0 0 0 0 1249095 0 0 0 0 0 0 899402 754148 0 0 0 0 1312209 916048 0 0 0 0 0 0 0 0 0 0 842739 0 0 208662 0 924872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLFSK MGYG000000196_04140 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,2FM28@200643|Bacteroidia,4AN5I@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 acd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_dehyd_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 2196346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2245098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613022 0 0 0 0 0 0 -AADLGLSDVTVK MGYG000002993_01622 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-170|s__CAG-170 sp000432135|m__MGYG000002993 1.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,2N6G4@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate-binding protein PnrA-like 1.0 tmpC 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 605593 0 0 0 0 388928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585327 0 0 0 0 678759 0 0 0 0 1590378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLHDVGQR MGYG000003683_01304 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CZ52@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsI 1.0 - 1.0 2.7.3.9 1.0 ko:K08483 1.0 ko02060,map02060 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N,PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 CE9 1.0 phosphoenolpyruvate--protein phosphotransferase. sugar--PEP phosphotransferase enzyme I. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1028768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1802929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1061184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLIR MGYG000004756_00803;MGYG000000074_02400;MGYG000000196_04138;MGYG000001562_02164;MGYG000001345_00398 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia 0.6 976|Bacteroidetes 1.0 C 1.0 Electron transfer flavoprotein 0.6 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1868918 0 0 1519033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLLPVDWDKTSTGK MGYG000001313_02440 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG1435@1|root,COG1435@2|Bacteria,4P1V6@976|Bacteroidetes,2FX4S@200643|Bacteroidia,4AV49@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 980394 0 0 0 0 805876 0 0 0 0 887509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLLPVDWDNTTTGKPTFGNNQQR MGYG000002455_04253 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG0614@1|root,COG0614@2|Bacteria,4NGP1@976|Bacteroidetes,2FNKG@200643|Bacteroidia,4AMD2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1322394 0 0 0 0 1076029 0 0 0 0 1255265 0 0 0 0 0 0 0 0 0 0 -AADLLR MGYG000003372_02346;MGYG000001777_01710;MGYG000002506_01324;MGYG000000074_02400;MGYG000002494_03510;MGYG000000196_04138;MGYG000002515_01853;MGYG000001337_03724;MGYG000001345_00398;MGYG000002477_02675 domain d__Bacteria 1.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,3XMFG@561|Escherichia 0.5 1236|Gammaproteobacteria 0.5 N 0.5 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation 0.5 fliG 0.5 GO:0001539,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0006996,GO:0008150,GO:0009288,GO:0009425,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0040011,GO:0042802,GO:0042995,GO:0043226,GO:0043228,GO:0044085,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0044780,GO:0044781,GO:0048870,GO:0051179,GO:0051674,GO:0070925,GO:0071840,GO:0071944,GO:0071973,GO:0097588 0.5 - 0.9 ko:K02410 0.5 ko02030,ko02040,map02030,map02040 0.5 - 0.9 - 0.9 - 0.9 ko00000,ko00001,ko02035 0.5 - 1.0 - 1.0 - 1.0 FliG_C,FliG_M,FliG_N 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9 0.9 0.9 0.9 Bacterial chemotaxis;Flagellar assembly 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 863849 0 0 0 0 0 771596 0 0 0 0 0 0 0 0 0 0 0 0 1424544 0 0 1161464 0 0 0 0 0 0 0 0 0 0 0 208152 0 0 0 0 0 0 0 0 0 0 1106184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1645232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLMADILGGK MGYG000000175_02877 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Muricomes|s__Muricomes sp000509105|m__MGYG000000175 1.0 COG1609@1|root,COG1609@2|Bacteria,1UP7H@1239|Firmicutes,25H7W@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 LacI,Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2613008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2999552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2468343 0 0 0 0 0 0 0 0 0 -AADLMK MGYG000001770_02443;MGYG000003697_02383;MGYG000004797_03938;MGYG000002478_03963;MGYG000002293_02246;MGYG000003486_01435;MGYG000001306_02131;MGYG000000243_01707;MGYG000001787_01419 domain d__Bacteria 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 0.5555555555555556 976|Bacteroidetes 0.8888888888888888 EF 0.5555555555555556 COG0462 Phosphoribosylpyrophosphate synthetase 0.5555555555555556 prs 0.8888888888888888 - 1.0 2.7.6.1 0.8888888888888888 ko:K00948 0.8888888888888888 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 0.8888888888888888 M00005 0.8888888888888888 R01049 0.8888888888888888 RC00002,RC00078 0.8888888888888888 ko00000,ko00001,ko00002,ko01000 0.8888888888888888 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 Pentose phosphate pathway;Carbon metabolism;Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 0.8888888888888888 none 1.0 0 0 0 0 0 649457 0 0 0 0 0 0 0 0 0 0 0 1853994 0 0 0 1483759 1532439 0 0 0 0 1914146 0 0 0 0 2094212 0 0 0 0 0 0 0 807298 0 0 583691 0 0 0 0 0 0 0 0 0 228847 0 305624 0 0 0 0 0 1263182 0 0 0 2063155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 694512 0 0 0 0 0 0 0 0 0 2440497 0 0 0 0 0 1115574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLTAH MGYG000002293_01420;MGYG000003697_02155 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2781972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1574975 0 0 0 0 3476657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLTAHQVL MGYG000002293_01420;MGYG000003697_02155 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6227108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4123412 0 0 0 0 6045133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLTAHQVLVN MGYG000002293_01420;MGYG000003697_02155 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 509508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319758 0 0 0 0 812060 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379868 0 0 0 0 0 0 0 2079175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1622957 0 0 0 0 1778726 0 0 675463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLTAHQVLVNIK MGYG000002293_01420;MGYG000003697_02155 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1108170 7044551 0 2376983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3595439 2183254 4302412 0 0 0 0 5449212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLTTVEAGK MGYG000001300_02558 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3WIYH@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 ET 1.0 Belongs to the bacterial solute-binding protein 3 family 1.0 artP 1.0 - 1.0 - 1.0 ko:K02029,ko:K02030 1.0 - 1.0 M00236 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1.3 1.0 - 1.0 - 1.0 SBP_bac_3,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101714 0 0 0 0 0 0 0 -AADLVISAESAK MGYG000000177_01234 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 COG2998@1|root,COG2998@2|Bacteria,1UI9K@1239|Firmicutes,25EEI@186801|Clostridia,36S90@31979|Clostridiaceae 1.0 2|Bacteria 1.0 H 1.0 Copper amine oxidase N-terminal domain 1.0 - 1.0 - 1.0 - 1.0 ko:K05772 1.0 ko02010,map02010 1.0 M00186 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.6.2,3.A.1.6.4 1.0 - 1.0 - 1.0 CAP,Cu_amine_oxidN1,NHL,PBP_like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4304068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9796500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLVQQR MGYG000003266_00462 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900762015|m__MGYG000003266 1.0 COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria,4CURU@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 NU 1.0 Endoribonuclease that initiates mRNA decay 1.0 rny 1.0 - 1.0 - 1.0 ko:K18682 1.0 ko03018,map03018 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03019 1.0 - 1.0 - 1.0 - 1.0 DUF3552,HD,KH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADLVSQMTVDDK MGYG000001619_00077 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA9502|s__UBA9502 sp900540335|m__MGYG000001619 1.0 COG1472@1|root,COG3266@1|root,COG5263@1|root,COG1472@2|Bacteria,COG3266@2|Bacteria,COG5263@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,21ZUH@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Glycosyl hydrolase family 3 C-terminal domain 1.0 - 1.0 - 1.0 3.2.1.21 1.0 ko:K05349 1.0 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 1.0 - 1.0 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 1.0 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH3 1.0 - 1.0 Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C 1.0 - 1.0 GH3 1.0 GH3 1.0 GH3 1.0 beta-glucosidase. gentobiase. Wide specificity for beta-D-glucosides.-!-Some examples also hydrolyze one or more of the following: beta-D- galactosides, alpha-L-arabinosides, beta-D-xylosides and beta-D- fucosides. Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose. 1.0 1.0 1.0 1.0 Phenylpropanoid biosynthesis;Metabolic pathways;Starch and sucrose metabolism;Cyanoamino acid metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADM(Oxidation)TGADIEAMTR MGYG000002515_03654;MGYG000002323_03993;MGYG000002500_00408;MGYG000002507_00343;MGYG000002502_01843;MGYG000002366_04479;MGYG000000235_04430 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,3ZIPY@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381387 416940 518714 0 727727 606371 0 904107 0 0 0 0 0 0 0 0 0 0 0 0 779033 0 761781 0 0 0 0 596634 0 0 0 0 0 0 0 0 501668 0 440726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400164 0 400574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 554798 0 0 878524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618549 0 0 0 0 0 0 213871 0 0 0 0 0 0 0 0 632240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADMTGADIEAM(Oxidation)TR MGYG000002515_03654;MGYG000002323_03993;MGYG000002500_00408;MGYG000002507_00343;MGYG000002502_01843;MGYG000002366_04479;MGYG000000235_04430 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,3ZIPY@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436973 0 552008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300248 0 363698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADMTGADIEAMTR MGYG000002515_03654;MGYG000002323_03993;MGYG000002500_00408;MGYG000002507_00343;MGYG000002502_01843;MGYG000002366_04479;MGYG000000235_04430 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,3ZIPY@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1689115 1348862 1660780 1661535 1041343 2892723 3201843 2774055 1692816 2549691 847192 2005120 0 1726024 1406529 471242 2133940 0 1600848 1884759 2191816 2458614 0 4133846 1805150 1823073 2164896 0 2429615 2502606 1881752 1864501 1725210 2197579 1780422 2141445 1459263 1952458 5395766 5318683 5234087 6306209 6092118 12613396 7300910 4752233 4709318 9479303 2679525 4673654 4094438 7876329 5712408 4546235 7666780 0 7208652 4739219 7259876 12843135 0 8793634 7262288 6052492 4716327 0 9920299 7842708 3412694 5119935 6680694 5164164 6118575 5180915 5423258 5848155 1652665 1341046 2048591 1234816 2187554 4135349 2184691 2096090 2046367 2337924 1663321 1945102 1796749 1978948 1665287 1897920 2147269 0 1645467 1637096 2121335 3594215 0 4399857 2231494 1547293 1588790 0 1523077 1816683 2029265 1649015 1695069 2298643 2445611 1968753 1318971 2205171 3582646 3115152 3143344 3262602 3030782 6070555 4487240 3777653 2567175 6023201 2980074 2879410 4780312 3085234 2856826 2817858 3233869 0 3366825 2172112 4621339 5051099 0 3880550 3824954 2923673 4272588 0 3367276 3189689 1791876 2854852 3581770 4643138 4701309 3898847 2546743 3037548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADN(Deamidated)VAALIDK MGYG000000142_01624;MGYG000000133_00237 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 1.0 186801|Clostridia 1.0 M 1.0 Cobalt chelatase (CbiK) 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2056286 0 0 0 0 0 0 0 0 0 1199147 0 0 1484040 0 0 1257369 1858878 1161664 0 0 0 0 0 0 0 0 0 0 1258993 0 0 0 0 0 0 1168266 0 0 0 0 2666628 0 0 0 0 1277856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2634002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 503928 1423276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADNNLTAPMYLR MGYG000000003_00524 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,2G3E7@200643|Bacteroidia,22UFS@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 590444 0 0 0 0 0 0 0 0 0 0 0 0 0 880094 0 0 0 0 0 0 0 0 0 0 1012764 0 0 0 0 0 0 0 0 0 0 0 0 576496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397526 0 0 0 0 0 0 0 0 0 0 0 0 0 930692 0 0 0 0 0 0 0 0 0 0 736806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADPEIAGYSSNADVQR MGYG000002478_00836 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AWE5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 445796 0 0 444986 0 0 0 0 0 0 0 0 0 0 920272 0 0 0 0 1021599 0 0 0 0 832298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADPELAITEFK MGYG000001306_01209 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 462336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1503484 0 0 0 0 2138128 0 0 0 0 1514861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADPELAITEFKR MGYG000001306_01209 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 135255 0 68166 0 0 0 0 0 0 0 0 0 0 0 0 68662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119620 0 0 58344 722072 0 1008289 935986 1084115 0 0 993064 838245 0 0 0 0 0 0 1322092 1001149 3250666 0 0 0 0 3646293 0 0 865345 940713 2860686 0 0 981233 0 912882 919375 1006228 764413 701217 1027768 54317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172795 0 0 0 0 0 0 0 0 0 0 74979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADPELAVADFK MGYG000003693_02548 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1729464 0 0 0 0 1192722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADPELAVADFKR MGYG000003693_02548 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587163 0 0 0 2669544 0 0 0 0 3749323 0 0 0 0 2507941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70320 0 0 0 0 190323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498153 0 0 0 0 439454 0 0 0 0 341434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADPY(Didehydro)VVVDSK MGYG000002057_00680 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Dysosmobacter|s__Dysosmobacter sp001916835|m__MGYG000002057 1.0 2DX6Y@1|root,343NU@2|Bacteria,1VVG9@1239|Firmicutes,25GRP@186801|Clostridia,2N903@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADPYVVVDSK MGYG000002057_00680 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Dysosmobacter|s__Dysosmobacter sp001916835|m__MGYG000002057 1.0 2DX6Y@1|root,343NU@2|Bacteria,1VVG9@1239|Firmicutes,25GRP@186801|Clostridia,2N903@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 13327530 10286266 0 0 0 11879019 19104982 0 0 0 0 9863494 0 0 0 0 0 0 0 0 0 8824592 0 14863500 11810977 13749406 13280559 0 13719790 13252180 13026022 0 0 14995018 0 0 14186612 0 185921 0 0 0 0 0 156963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1606625 872361 0 0 0 1038405 2391002 0 0 0 0 702824 0 0 0 0 0 0 0 0 0 390486 0 1179653 1982021 1355312 1532397 0 1368585 797464 939674 0 0 1736970 0 0 1562414 0 7609379 5921404 0 0 0 7915152 7801366 0 0 0 0 7812397 0 0 0 0 0 0 0 0 0 5701730 0 5785288 8053836 9390127 7594872 0 9011407 8038184 6326712 0 0 10518233 0 0 9215739 0 1660877 1047788 0 0 0 1755687 1648028 0 0 0 0 1158068 0 0 0 0 0 0 0 0 0 1599437 0 1901505 1738320 1638558 1397245 0 2052765 1585571 1531427 0 0 1839913 0 0 1938007 0 -AADPYVVVDSKLQMK MGYG000002057_00680 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Dysosmobacter|s__Dysosmobacter sp001916835|m__MGYG000002057 1.0 2DX6Y@1|root,343NU@2|Bacteria,1VVG9@1239|Firmicutes,25GRP@186801|Clostridia,2N903@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADQGN(Deamidated)GVAC(Carbamidomethyl)LYGNYSGDNMNVK MGYG000004735_02294 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,21YFJ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 2.7.1.121 1.0 ko:K05878 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3058548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADQGNGVAC(Carbamidomethyl)LYGNYSGDNMNVK MGYG000004735_02294 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,21YFJ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 2.7.1.121 1.0 ko:K05878 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2003746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADQIISTVK MGYG000000084_02402;MGYG000000573_00808;MGYG000001627_00605;MGYG000002059_00658 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,25VXK@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 628406 0 0 0 0 0 373698 0 0 0 0 671346 0 0 0 0 0 0 0 0 0 0 455619 0 0 199009 0 0 0 0 0 0 374851 0 0 0 0 0 294955 0 0 0 0 0 411047 0 0 0 0 0 526219 0 0 0 264434 722134 0 0 0 0 554317 0 0 0 0 165517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 749266 0 0 0 0 0 0 0 0 0 0 0 137358 0 0 0 0 0 507698 0 0 0 0 0 0 0 0 0 0 1606865 0 0 1519857 0 0 0 0 0 4840531 0 0 0 0 1829421 3971280 0 0 0 1944992 2612880 1837263 0 0 0 6316887 0 2425314 2806658 0 1422283 0 0 0 0 1856330 0 0 0 0 0 0 0 0 0 0 0 562880 0 0 0 0 0 1301264 0 0 0 0 1115478 0 0 0 0 1223364 0 633723 0 0 0 0 0 0 0 0 -AADQLGLPYLK MGYG000001302.1_00591 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG3193@1|root,COG3193@2|Bacteria,4NKJX@976|Bacteroidetes,2FN1N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Starch-binding associating with outer membrane 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8387581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADQSYLSGGSWGAGDVK MGYG000000243_02119 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444804 0 0 0 0 0 0 0 0 0 657354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADQSYLSGGSWGAGDVKYEDLNNDGK MGYG000000243_02119 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 484463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596296 0 0 426209 0 446245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163803 0 0 441273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 370770 0 319213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADQTDDNWK MGYG000001319_01847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,4BW46@830|Butyrivibrio 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1736197 0 0 0 0 768943 0 0 0 0 1674540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADREAVEALLAK MGYG000002494_04092 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,3XP1B@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate 1.0 purL 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.0 6.3.5.3 1.0 ko:K01952 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04463 1.0 RC00010,RC01160 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 1.0 AIRS,AIRS_C,GATase_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylformylglycinamidine synthase. phosphoribosylformylglycinamidine synthetase. - ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D- ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D- ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138580 0 0 0 0 0 0 0 0 0 -AADREGAPM(Oxidation)KR MGYG000004271_01917 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit 1.0 rpsR 1.0 - 1.0 - 1.0 ko:K02963 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S18 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADREGAPMKR MGYG000004271_01917 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit 1.0 rpsR 1.0 - 1.0 - 1.0 ko:K02963 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S18 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADRTGRPATVK MGYG000000187_00978 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADSFLKDNC(Carbamidomethyl)QDIVSAK MGYG000000133_02045 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3XZ9K@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location CytoplasmicMembrane, score 1.0 ntpI 1.0 - 1.0 - 1.0 ko:K02123 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 V_ATPase_I 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 713281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109801 0 0 0 0 0 0 0 0 0 0 0 0 123435 0 0 0 0 0 0 0 0 370470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379510 0 0 202862 0 0 0 0 0 0 0 151540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 818799 0 0 0 0 0 0 0 0 882116 0 0 1084034 0 0 0 0 0 0 0 0 0 0 0 0 596829 0 0 1013555 0 0 794560 0 0 0 0 527595 0 -AADSNVKVDAGK MGYG000001356_00079 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter sp000177015|m__MGYG000001356 1.0 COG1404@1|root,COG1404@2|Bacteria,1UM3J@1239|Firmicutes 1.0 1239|Firmicutes 1.0 O 1.0 S-layer homology domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 57877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1205966 0 0 0 0 0 0 0 0 0 -AADSVVEELK MGYG000001881_01572 genome d__Bacteria|p__Verrucomicrobiota|c__Verrucomicrobiae|o__Verrucomicrobiales|f__Akkermansiaceae|g__Akkermansia|s__Akkermansia muciniphila_A|m__MGYG000001881 1.0 COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,2ITQ1@203494|Verrucomicrobiae 1.0 203494|Verrucomicrobiae 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 - 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADSVVEELKK MGYG000001881_01572 genome d__Bacteria|p__Verrucomicrobiota|c__Verrucomicrobiae|o__Verrucomicrobiales|f__Akkermansiaceae|g__Akkermansia|s__Akkermansia muciniphila_A|m__MGYG000001881 1.0 COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,2ITQ1@203494|Verrucomicrobiae 1.0 203494|Verrucomicrobiae 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 - 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADVDEALQR MGYG000002494_00912 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0028@1|root,COG0028@2|Bacteria,1MWKP@1224|Proteobacteria,1RNYT@1236|Gammaproteobacteria,3ZJ68@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 EH 1.0 Thiamine pyrophosphate enzyme, central domain 1.0 poxB 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009987,GO:0016020,GO:0016043,GO:0016054,GO:0016491,GO:0016903,GO:0019752,GO:0019842,GO:0022607,GO:0030976,GO:0032787,GO:0036094,GO:0042802,GO:0042867,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052737,GO:0052738,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575,GO:1901681 1.0 1.2.3.3,1.2.5.1 1.0 ko:K00156,ko:K00158 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00207,R03145 1.0 RC00860,RC02745 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iSF_1195.SF0826,iSFxv_1172.SFxv_0895,iS_1188.S0867 1.0 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate oxidase. | pyruvate dehydrogenase (quinone). pyruvic oxidase. | pyruvate oxidase. Two reducing equivalents are transferred from the resonant carbanion/enamine forms of 2-hydroxyethyl-thiamine-diphosphate to the adjacent flavin cofactor, yielding 2-acetyl-thiamine diphosphate (AcThDP) and reduced flavin.-!-FADH is reoxidized by O2 to yield H2O2 and FAD and AcThDP is cleaved phosphorolytically to acetyl phosphate and thiamine diphosphate. | This bacterial enzyme is located on the inner surface of the cytoplasmic membrane and coupled to the respiratory chain via ubiquinone.-!-Does not accept menaquinone.-!-Activity is greatly enhanced by lipids.-!-Requires thiamine diphosphate.-!-The enzyme can also form acetoin. H(+) + O2 + phosphate + pyruvate = acetyl phosphate + CO2 + H2O2. | a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3389528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5013346 0 4394560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADVDTLGDLVQFNK MGYG000002834_00467;MGYG000003697_01441 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 596930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 761045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 851086 0 0 0 0 947512 0 0 0 0 690436 0 0 0 0 951181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1063281 0 0 0 0 1149215 0 0 0 0 0 0 0 1241567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1484574 0 0 0 0 756578 0 0 0 0 0 0 0 0 0 1367941 0 0 651599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683851 0 0 0 0 410908 0 0 0 0 537197 0 0 0 0 0 0 0 0 0 880382 -AADVDTVGDLVK MGYG000001420_02949;MGYG000004006_01195;MGYG000001562_01972;MGYG000004536_01537;MGYG000000414_01251;MGYG000002082_00459;MGYG000000003_00060;MGYG000003469_01152;MGYG000001546_01244;MGYG000000074_01934;MGYG000003952_00926;MGYG000004658_00182;MGYG000000053_00720;MGYG000001302.1_01192 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,22UPE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 1946497 1682108 943569 1995991 1148484 1981229 1923246 1309387 2201620 2033029 985475 2231543 1341566 2305552 2521408 1437621 2310384 0 2457126 2319629 2572287 1900105 0 2310761 1831441 2281392 2697321 0 1738406 3128587 1443302 2638675 1273290 806409 2002799 2447715 2022821 870071 1721710 927854 1725948 1950333 1403312 1158201 1004478 1842524 1855663 2316354 1085750 1875495 1064232 2079331 2236785 1309142 1306030 0 1957404 2054083 1581640 1320118 0 1034476 1743299 1784027 1707243 0 1523627 1707079 951646 1586597 1673780 1368398 1764037 1756910 1758948 1602039 2207576 1439634 2508110 1710748 2449391 1560444 1945731 2013868 2670176 1902441 1831107 2486349 1498429 2361148 1810880 1406766 1637283 0 1928281 2298224 2437918 1237365 0 1851900 2052677 1983010 1769489 0 2117725 2665540 1712712 1138651 1837271 2351643 2015424 2857449 2200934 2296172 1360185 1166765 2440049 2155682 1857859 2613156 2045040 2149739 2020011 2219760 1526753 2220880 987812 2147171 3108033 1729673 1951378 0 2373556 1456074 0 451765 0 487881 2240686 1811458 1574033 0 2444409 2462458 1697421 2326319 2370175 0 1538680 1841138 2547491 1954654 3838862 2798656 3417687 5780010 5518491 4869535 3796860 4012194 4330215 3861687 2008307 3675131 3958695 2526102 3670630 4437052 4393561 0 6295233 7235763 2938754 3815155 0 5252575 3814981 4844579 3180442 0 3906075 5906278 3132201 3068179 2141886 1240012 4322814 3368939 4844224 3719947 -AADVDTVGDLVK(Lys->Arg) MGYG000001420_02949;MGYG000004006_01195;MGYG000001562_01972;MGYG000004536_01537;MGYG000000414_01251;MGYG000002082_00459;MGYG000000003_00060;MGYG000003469_01152;MGYG000001546_01244;MGYG000000074_01934;MGYG000003952_00926;MGYG000004658_00182;MGYG000000053_00720;MGYG000001302.1_01192 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,22UPE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 775799 0 0 0 0 0 0 0 0 0 0 1171671 0 0 0 0 0 0 1358535 0 0 0 0 1405285 0 0 0 0 0 0 0 0 0 0 0 1148781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADVDTVGDLVR MGYG000001415_01644 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,22UPE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 987736 1025602 928215 947493 0 0 1119102 1154224 1063542 1039466 1035960 0 0 0 0 0 0 0 0 1057315 0 1029914 0 1419874 0 0 1235018 0 0 1007651 1141682 1099876 1193637 1510762 1026558 1292548 1103995 0 0 174763 0 0 0 212672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311688 0 0 0 0 0 273385 0 240660 284496 364767 197466 0 525660 289954 271237 349904 129503 333363 0 0 0 0 0 0 0 0 0 0 0 0 394907 0 531214 262294 0 0 187357 293122 284932 0 579910 0 607376 369528 305011 624653 785063 586273 446731 0 673148 616488 506831 418575 466211 590998 0 0 0 0 0 0 0 0 645527 0 0 0 0 0 471213 393520 0 0 0 571288 501192 547518 403814 441356 514515 445629 0 360905 609892 178668 341006 0 0 0 0 0 511394 621056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 598980 0 0 0 609340 405779 562852 0 0 0 0 594912 -AADVETL(Xle->Asn)GDLVQFNKTDLLK MGYG000001346_01492;MGYG000002478_00772;MGYG000000013_02209;MGYG000004763_00952;MGYG000004876_02791;MGYG000003681_02079;MGYG000000243_01944;MGYG000000098_01975;MGYG000001378_05000;MGYG000004185_01136;MGYG000001370_01722 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,4AKBJ@815|Bacteroidaceae 0.8181818181818182 976|Bacteroidetes 1.0 K 0.9090909090909091 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 0.9090909090909091 rpoA 0.9090909090909091 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 0.9090909090909091 2.7.7.6 0.9090909090909091 ko:K03040 0.9090909090909091 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 0.9090909090909091 M00183 0.9090909090909091 R00435,R00441,R00442,R00443 0.9090909090909091 RC02795 0.9090909090909091 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 0.9090909090909091 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 0.9090909090909091 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16623983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2174050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15114788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADVETLGDLVQFNK MGYG000002275_02090;MGYG000001306_02687;MGYG000002281_02248;MGYG000002935_01266;MGYG000000224_00448;MGYG000000243_01944;MGYG000001378_05000;MGYG000002560_00263;MGYG000001599_01824;MGYG000004185_01136;MGYG000001337_03861;MGYG000001346_01492;MGYG000000105_02032;MGYG000000054_03885;MGYG000002478_00772;MGYG000000013_02209;MGYG000002293_00479;MGYG000004763_00952;MGYG000004876_02791;MGYG000003681_02079;MGYG000001433_02303;MGYG000000098_01975;MGYG000002933_02108;MGYG000003312_02964 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,4AKBJ@815|Bacteroidaceae 0.7083333333333334 976|Bacteroidetes 1.0 K 0.9166666666666666 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 0.9166666666666666 rpoA 0.9166666666666666 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 0.9166666666666666 2.7.7.6 0.9166666666666666 ko:K03040 0.9166666666666666 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 0.9166666666666666 M00183 0.9166666666666666 R00435,R00441,R00442,R00443 0.9166666666666666 RC02795 0.9166666666666666 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 0.9166666666666666 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 0.9166666666666666 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 0.9166666666666666 0.9166666666666666 0.9166666666666666 0.9166666666666666 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 0.9166666666666666 none 1.0 1661139 1427594 1703241 2014897 1410357 1457056 2629494 1238740 2062829 1267905 2402507 1599589 1563830 1235366 1126715 1963027 1663315 1386881 1286523 1287356 1503875 1122321 1633767 1776169 1169594 1362664 1812003 1313810 1860047 1980171 2177410 1246141 2259540 1818395 1542606 2121102 1484698 2075032 2813504 0 0 0 3045697 0 3837197 4316518 3227251 3836905 4887668 4658937 0 3876035 3448565 3987633 3663680 4051883 0 0 0 0 5568981 3026502 3829542 4168736 3602440 3908524 0 0 2477024 3289540 0 2452745 2839241 0 3253803 2839759 1088478 888918 1212831 1182447 2599906 1687535 1857735 1121709 1720720 1016250 2505977 1506897 1543385 1533479 1240040 1445341 1214708 2703053 1113339 1163928 1376638 1133442 2464072 1859507 1054049 1524343 942041 2136565 1556212 1549755 1666070 1192756 1243075 1047843 1157960 1853162 1292317 1696414 970076 784633 1000508 680516 920355 949076 1102549 771957 736085 760485 1228721 1142587 1189498 735609 648800 1078805 788526 1336799 992786 818380 1408944 909998 1679748 963474 805701 980980 1040862 641782 805801 771955 672007 856333 1176315 934704 937766 1362552 827450 997088 1369442 971752 823799 1197349 2127267 1439212 1689058 1935197 1449041 531274 1957804 981968 2271740 846434 929907 2273247 1223538 3694035 1545735 2648420 925232 1552441 2891890 1492691 1843424 1954796 1547358 3192989 999989 1664635 1127238 1037470 473994 1745620 1785438 579246 1341249 1045430 -AADVETLGDLVQFNKTDLLK MGYG000001346_01492;MGYG000002478_00772;MGYG000000013_02209;MGYG000004763_00952;MGYG000004876_02791;MGYG000003681_02079;MGYG000000243_01944;MGYG000000098_01975;MGYG000001378_05000;MGYG000004185_01136;MGYG000001370_01722 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,4AKBJ@815|Bacteroidaceae 0.8181818181818182 976|Bacteroidetes 1.0 K 0.9090909090909091 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 0.9090909090909091 rpoA 0.9090909090909091 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 0.9090909090909091 2.7.7.6 0.9090909090909091 ko:K03040 0.9090909090909091 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 0.9090909090909091 M00183 0.9090909090909091 R00435,R00441,R00442,R00443 0.9090909090909091 RC02795 0.9090909090909091 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 0.9090909090909091 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 0.9090909090909091 none 1.0 0 0 0 0 5971810 23126640 30428436 7544753 0 5179440 2634944 0 35650878 0 0 6825143 0 10598450 0 0 8628220 16858937 340743 25152816 23677746 0 0 2984021 0 8384357 46255796 37695527 5830280 0 0 0 0 53902430 0 0 2909845 0 36415431 23508006 26272209 5184509 0 12555897 47252967 0 10687349 0 0 47163625 0 0 0 0 0 26548914 11920805 20194093 29080196 0 0 51084 0 0 26043758 36783398 18778369 0 0 0 0 11615093 0 0 0 0 13342008 9781976 24702061 0 0 0 33587723 0 21384830 0 0 23496993 0 37343718 0 0 9347018 8733869 23821783 46771450 78659 0 0 8602158 0 487195 0 10814124 0 0 0 0 0 7146049 0 0 8567196 0 0 8031227 14898984 14124234 0 0 54351 0 138183 0 0 12536649 0 8863355 0 0 0 8181992 33632746 0 0 0 0 0 0 12893898 0 17574927 0 0 0 0 0 11259366 0 0 10417035 0 9598639 8699156 16586135 11103442 0 5187729 36117659 0 36183685 0 0 4517693 0 1437087 0 0 0 0 17474412 30600366 22281160 0 0 0 0 21463530 10459139 7954656 0 0 0 0 0 0 -AADVETLGELVK MGYG000002438_02235;MGYG000000138_02862;MGYG000000696_01636;MGYG000001489_02641;MGYG000002218_02493 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,22XAK@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 350809 0 0 0 0 0 0 0 0 0 500242 0 0 0 0 0 0 0 488925 0 0 0 0 0 0 149054 0 377543 0 0 389491 0 0 0 0 346471 0 0 587778 0 0 0 0 0 0 0 0 0 757622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1602679 0 0 661178 0 0 0 0 627186 0 0 0 0 0 0 0 0 0 0 0 0 375017 0 0 0 0 0 0 0 605117 0 0 0 0 0 0 0 0 0 0 0 379460 0 0 0 0 477216 0 0 1128471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386736 0 0 4263693 0 482330 0 0 0 0 384146 0 2499160 0 0 1528315 0 0 0 0 843929 0 0 1542116 0 0 0 0 0 0 0 0 0 3033559 0 0 0 0 0 0 0 0 0 1425547 0 0 0 0 1423769 0 0 0 0 1568684 0 0 0 0 0 -AADVGADLVGK MGYG000002964_00576;MGYG000000127_05422;MGYG000002478_02415;MGYG000004642_01840;MGYG000003926_01060;MGYG000004769_01663;MGYG000003279_00415;MGYG000004899_01967;MGYG000000224_02069;MGYG000002067_00146;MGYG000004797_03435;MGYG000003311_01901;MGYG000001732_02364;MGYG000000400_02184;MGYG000002721_02306;MGYG000002143_00403;MGYG000001502_01055;MGYG000000146_02298;MGYG000001599_00722;MGYG000002727_01191;MGYG000000215_00358;MGYG000002246_00264;MGYG000001725_01369;MGYG000003681_01853;MGYG000004756_00108;MGYG000001500_00249;MGYG000002905_01531;MGYG000001780_04010;MGYG000004573_00484;MGYG000003802_01296;MGYG000000138_00647;MGYG000001429_01938;MGYG000000179_01304;MGYG000001657_00904;MGYG000003282_00044;MGYG000001714_03130;MGYG000000098_01325;MGYG000004663_01400;MGYG000001661_00238;MGYG000000038_02712;MGYG000000262_00960;MGYG000004658_02698;MGYG000004482_01395;MGYG000000121_00356;MGYG000003142_02543;MGYG000002540_01543;MGYG000004760_01159;MGYG000001447_00382;MGYG000000198_01375;MGYG000001666_00309;MGYG000002218_02851;MGYG000003558_00139;MGYG000000170_02041;MGYG000001616_01732;MGYG000000054_00158;MGYG000001389_02398;MGYG000001164_01682;MGYG000002944_02433;MGYG000003449_01590;MGYG000004667_04890;MGYG000001770_01042;MGYG000004263_01339;MGYG000004707_00909;MGYG000004885_00074;MGYG000001546_02682;MGYG000002455_01921;MGYG000003374_01704;MGYG000004720_00672;MGYG000003697_01769;MGYG000002229_02459;MGYG000000466_01166;MGYG000004479_01013;MGYG000000117_02105;MGYG000002794_01654;MGYG000001651_01344;MGYG000002717_00152;MGYG000004285_00137;MGYG000002673_01165;MGYG000003221_00731;MGYG000002926_01074;MGYG000001423_02271;MGYG000002737_00797;MGYG000004763_00680;MGYG000002082_01918;MGYG000000034_02196;MGYG000000198_03536;MGYG000004536_00590;MGYG000002720_01717;MGYG000000202_00737;MGYG000004727_01727;MGYG000000236_00786;MGYG000002033_00992;MGYG000002084_00244;MGYG000002212_02487;MGYG000001683_01956;MGYG000000735_01187;MGYG000000243_02430;MGYG000002156_00692;MGYG000001754_00461;MGYG000002171_00877;MGYG000001167_00090;MGYG000004847_00160;MGYG000000216_02379;MGYG000000733_00463;MGYG000003589_01348;MGYG000001311_00647;MGYG000002036_00419;MGYG000000071_02010;MGYG000000095_03614;MGYG000003701_01447;MGYG000000142_02080;MGYG000001576_02602;MGYG000001493_00044;MGYG000002315_01585;MGYG000002953_01954;MGYG000002945_02680;MGYG000001310_00146 domain d__Bacteria 1.0 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,4AKW4@815|Bacteroidaceae 0.18803418803418803 186801|Clostridia 0.5470085470085471 C 1.0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane 0.8376068376068376 hppA 1.0 - 1.0 3.6.1.1 1.0 ko:K15987 1.0 ko00190,map00190 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 3.A.10.1 1.0 - 1.0 - 1.0 H_PPase 0.5726495726495726 - 1.0 - 1.0 - 1.0 - 1.0 inorganic diphosphatase. pyrophosphate phosphohydrolase. Specificity varies with the source and with the activating metal ion.-!-The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9. cf. EC 7.1.3.1. diphosphate + H2O = H(+) + 2 phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation 1.0 none 1.0 4556785 3655282 2940601 3996882 3553834 4139419 3638943 3920894 3783655 3962467 3202024 3976094 2963096 4184894 4650874 3843381 4508943 3431874 4182792 4834594 4825418 4098488 3742011 3559561 4155171 4880447 4168147 3616827 4364546 3940466 3000113 3980776 3421268 4141721 4488420 4218330 4284991 3507244 4072972 2668196 2608641 3453289 3081845 2261802 3728753 3976997 2453051 3592332 2476937 3207953 2796808 0 0 2292654 3717724 2804685 3199766 3532095 3064447 1829237 2286011 2559383 3155383 3212411 3430985 2463020 3912890 2525909 3686713 0 2789956 3892083 0 4070604 3300974 3077308 6124344 3916413 4667246 5647184 4151903 3729945 4899064 5080374 4696782 5287171 3107727 3268988 3615366 4722904 5342154 4323217 5495217 4652920 5386374 5693130 4730723 4418872 4171008 3744885 5267721 4565801 5418234 3887081 5143740 4528175 3910528 4503974 3885473 4971455 3288273 5174632 5607471 4131123 3672143 3408527 4150182 3622478 3553709 3943649 3938468 3489177 3697184 4651279 2837602 3071408 2536048 3927867 3706795 3020615 5195859 6397204 3804514 4120529 3011108 3714132 5792284 4448670 3799100 3594566 3677667 6025124 4981682 3204175 2939358 3080950 4495932 3058647 3875035 4153386 3435534 4602702 0 2332545 2681887 0 2843408 2742771 3164457 3885952 3177451 3039220 1796584 2974892 2020612 0 2541474 2595340 3193781 3865471 3088166 0 2640249 0 3415678 2549821 2412969 2707959 2525377 3358697 4871528 3139127 2512051 2272053 1969740 2448850 2494147 2169669 3200587 3019018 -AADVGADLVGKVEAGIPEDDPR MGYG000002964_00576;MGYG000000127_05422;MGYG000001500_00249;MGYG000002478_02415;MGYG000004642_01840;MGYG000002084_00244;MGYG000001780_04010;MGYG000002212_02487;MGYG000001683_01956;MGYG000004707_00909;MGYG000004769_01663;MGYG000003279_00415;MGYG000000179_01304;MGYG000000243_02430;MGYG000004899_01967;MGYG000000224_02069;MGYG000004720_00672;MGYG000000098_01325;MGYG000004797_03435;MGYG000002229_02459;MGYG000001661_00238;MGYG000000038_02712;MGYG000004479_01013;MGYG000000117_02105;MGYG000003589_01348;MGYG000000262_00960;MGYG000001311_00647;MGYG000002036_00419;MGYG000002717_00152;MGYG000002143_00403;MGYG000001502_01055;MGYG000002926_01074;MGYG000003701_01447;MGYG000000198_01375;MGYG000004763_00680;MGYG000001666_00309;MGYG000002727_01191;MGYG000000198_03536;MGYG000004536_00590;MGYG000001576_02602;MGYG000002720_01717;MGYG000003681_01853;MGYG000001493_00044;MGYG000004727_01727;MGYG000000236_00786;MGYG000002953_01954;MGYG000000054_00158;MGYG000001616_01732 domain d__Bacteria 1.0 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,4AKW4@815|Bacteroidaceae 0.2916666666666667 186801|Clostridia 0.5625 C 1.0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane 0.8958333333333334 hppA 1.0 - 1.0 3.6.1.1 1.0 ko:K15987 1.0 ko00190,map00190 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 3.A.10.1 1.0 - 1.0 - 1.0 H_PPase 0.5833333333333334 - 1.0 - 1.0 - 1.0 - 1.0 inorganic diphosphatase. pyrophosphate phosphohydrolase. Specificity varies with the source and with the activating metal ion.-!-The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9. cf. EC 7.1.3.1. diphosphate + H2O = H(+) + 2 phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation 1.0 none 1.0 697044 649380 764064 648587 614980 714218 855364 921023 1024715 1036593 809455 1155030 0 0 832960 657911 1011888 773698 836335 710774 751775 622217 1102118 758737 934569 748162 756156 708971 1633971 850872 844670 709339 787934 606060 0 874940 724327 590305 450087 632690 348459 452263 503598 704917 363941 674515 398360 2117320 629079 415094 0 0 533900 484371 332018 297195 415324 557209 577873 419240 498933 580642 2087383 482676 702428 613615 3599784 921030 706399 502788 353678 314274 0 394191 389517 477500 988724 655272 1229040 1136639 1113573 1521599 940916 1179219 804765 977440 1392068 1353263 0 0 1322258 948413 931020 750261 1143028 1381408 853126 850111 650780 683867 1088392 525771 682553 706738 1647099 987516 1045864 968097 926904 1010528 0 1134383 1102397 856491 816727 626885 886636 821336 584827 750707 629754 698277 579051 522181 611037 348387 0 0 589528 660914 1111070 987785 830323 301784 840494 718002 425007 605391 582119 620856 387591 563031 0 637575 614235 705288 944658 376699 0 727299 534215 763990 732428 0 0 980736 541554 570774 738951 281955 820041 150516 0 285886 0 0 926247 0 191688 333925 495935 1344616 381222 0 378922 104622 458065 786222 196286 406377 1027489 393374 232054 205852 0 0 0 572564 440834 0 -AADVIVGAK MGYG000001714_01518 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus_A|s__Coprococcus_A catus|m__MGYG000001714 1.0 COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,27IU1@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 CH 1.0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 1.0 pyrK_1 1.0 - 1.0 1.18.1.2,1.19.1.1 1.0 ko:K00528,ko:K16951 1.0 ko00920,ko01120,map00920,map01120 1.0 - 1.0 R00858,R10146,R10159 1.0 RC00065 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ferredoxin--NADP(+) reductase. | flavodoxin--NADP(+) reductase. FPR. In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe- 2S] ferredoxins, but in other bacteria it can also reduce bacterial 2[4Fe-4S] ferredoxins and flavodoxin.-!-Formerly EC 1.6.7.1 and EC 1.6.99.4. | This activity occurs in some prokaryotes and algae that possess flavodoxin, and provides low-potential electrons for a variety of reactions such as nitrogen fixation, sulfur assimilation and amino acid biosynthesis.-!-In photosynthetic organisms it is involved in the photosynthetic electron transport chain.-!-The enzyme also catalyzes EC 1.18.1.2. H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]. | NADP(+) + reduced [flavodoxin] = 2 H(+) + NADPH + oxidized [flavodoxin]. 1.0 1.0 1.0 1.0 Sulfur metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1179740 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADVKDISER MGYG000000271_02507;MGYG000004271_00779 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9,2.7.9.2 1.0 ko:K01007,ko:K08483 1.0 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060 1.0 M00173,M00374 1.0 R00199 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--protein phosphotransferase. | pyruvate, water dikinase. sugar--PEP phosphotransferase enzyme I. | pyruvate,water dikinase. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. | ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Phosphotransferase system (PTS);Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADVKDITDR MGYG000000255_01177 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3XZ65@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9,2.7.9.2 1.0 ko:K01007,ko:K08483 1.0 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060 1.0 M00173,M00374 1.0 R00199 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--protein phosphotransferase. | pyruvate, water dikinase. sugar--PEP phosphotransferase enzyme I. | pyruvate,water dikinase. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. | ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Phosphotransferase system (PTS);Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADVLR MGYG000001315_01867;MGYG000001619_00422 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.5 186801|Clostridia 1.0 C 0.5 electron transfer flavoprotein 0.5 etfB 0.5 - 1.0 - 1.0 ko:K03521 0.5 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.5 - 1.0 - 1.0 - 1.0 ETF 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 2998083 0 0 0 0 0 0 0 0 3948432 3736029 0 0 0 0 0 0 0 0 0 0 0 0 0 3952516 0 0 0 0 0 0 0 0 0 0 0 0 2665097 3759281 0 0 0 0 0 3438079 0 0 0 1757730 0 0 2962669 0 0 0 0 0 0 0 0 0 0 0 2724385 0 0 2484977 0 2884821 0 3627425 3882263 3088966 0 0 0 0 0 0 0 0 0 1989849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1666219 0 0 0 0 0 0 2894336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2025682 0 0 0 0 0 0 3325670 0 0 0 0 3983587 -AADVNPDTR MGYG000000262_00177 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,25WK3@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 - 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 521308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1915215 3106143 0 5906924 0 0 0 0 0 0 0 0 0 1617715 0 0 0 0 0 0 0 0 0 0 0 2405834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADVTPEQADEMGMK MGYG000002775_00885;MGYG000003266_00117;MGYG000002065_01444;MGYG000002919_01729;MGYG000001642_01358;MGYG000000188_00186 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CUI3@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Arginyl-tRNA synthetase 1.0 argS 1.0 - 1.0 6.1.1.19 1.0 ko:K01887 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03646 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 arginine--tRNA ligase. arginyl-tRNA synthetase. - ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 539714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1569210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADWFK MGYG000004763_01074 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG4659@1|root,COG4659@2|Bacteria,4NQFX@976|Bacteroidetes,2G2KC@200643|Bacteroidia,4AW04@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 FMN_bind 1.0 rnfG 1.0 - 1.0 - 1.0 ko:K03612 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 540053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 562715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 544994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADWVIDHSTIEEK MGYG000001255_02250;MGYG000001300_01811 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADYC(Carbamidomethyl)AQQAQQLR MGYG000002926_01306 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,2N6YH@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 - 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410291 0 0 587379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424084 0 0 0 0 531388 575462 0 0 0 0 0 0 0 496129 0 773454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADYEKLQDSAASAAAR MGYG000003694_00128 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter faecis|m__MGYG000003694 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 873598 0 0 0 0 884442 0 0 0 0 665277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADYEKLQSSVSSAAAR MGYG000002492_01471 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 419782 0 0 0 0 234299 0 0 0 0 214057 0 0 0 0 147791 0 130511 0 0 0 0 374416 0 416493 269928 878139 0 157944 0 0 293519 631142 213410 258772 255776 0 271078 0 1184732 0 312594 0 0 283401 0 225508 0 230115 664188 0 0 499318 221403 528241 305585 313490 0 291098 1009955 619234 856699 3237445 761769 1375215 753242 374295 0 0 770313 1458674 1428809 1361089 520568 0 1907092 575459 446674 0 485592 0 744193 789844 772485 562516 683848 665826 1619407 0 0 1369481 1039631 3507439 823354 1018114 0 676382 2465109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305618 0 0 0 0 0 0 0 0 0 0 164946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AADYIVTGQWAK MGYG000000179_00718 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,21Y18@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040851 0 0 0 0 0 0 0 0 0 -AAE(Glu->Asp)ELGVTYK MGYG000000200_00369 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp003471165|m__MGYG000000200 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4064986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2062269 0 0 4541382 0 0 0 0 0 3992275 0 0 0 3140324 0 3577869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3160471 0 0 0 3899388 0 0 0 0 0 0 0 0 1840441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAE(Glu->Gln)AYFLLAEAK MGYG000002478_01404;MGYG000004797_04332 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1844730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEA(Ala->Ser)YFLLAEAK MGYG000002478_01404;MGYG000004797_04332 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 703978 731798 0 0 617800 696349 0 0 0 0 0 676349 0 0 0 2415591 0 0 0 0 2756253 0 0 0 0 2326709 0 0 0 0 568417 0 710204 471649 0 600125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 807569 0 0 0 0 0 0 123674 0 0 0 -AAEAAAALKPGEALMLENLR MGYG000001415_01540 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 700560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 661551 772076 0 0 0 0 0 0 813621 0 776818 556431 0 124271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 235640 145274 0 0 0 0 0 0 177631 0 141586 122920 0 275905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175929 170047 0 0 0 0 0 0 405202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89243 0 654508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 710224 611492 0 0 0 0 0 0 157541 0 668532 192707 0 -AAEAAAKAEAEAANAPAEEAPAAET(Thr->Ala)TEAPAEA MGYG000002478_03159 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1136141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 779670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAAAKAEAEAANAPAEEAPAAETT(Thr->Ala)EAPAEA MGYG000002478_03159 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAAAKAETEAAATEEAPAAEATEAPAEA MGYG000000243_01032 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 906015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1057092 0 0 0 0 740529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAAAPAQGGK MGYG000000179_00066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1744@1|root,COG1744@2|Bacteria,1U4NN@1239|Firmicutes,24CRY@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Basic membrane protein 1.0 - 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23071052 10559520 16238200 24159910 6598863 5293968 7857731 6028035 21725922 39125918 14884511 18255547 4867483 42112877 22669790 12467353 13408786 0 18241027 10450783 17248894 7842461 0 12939603 26787473 30333739 32359668 0 39619138 6572776 17719340 7618384 23845339 14541369 9182011 30977864 20965905 16295809 -AAEAAAPAQGGK(Cation_Na) MGYG000000179_00066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1744@1|root,COG1744@2|Bacteria,1U4NN@1239|Firmicutes,24CRY@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Basic membrane protein 1.0 - 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1241521 0 0 0 0 0 0 616527 0 0 0 0 -AAEAAAQAQNAK MGYG000001780_04661 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__|m__MGYG000001780 1.0 COG0845@1|root,COG0845@2|Bacteria,4NECC@976|Bacteroidetes,2FMDD@200643|Bacteroidia,4ANZR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Auxiliary transport protein, membrane fusion protein (MFP) family protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01993 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 639491 0 0 0 0 0 975955 641994 0 722574 1901239 695314 403841 744134 687181 0 659917 0 656312 0 0 0 0 0 761471 868187 931259 0 736375 841268 774480 0 0 922474 0 840608 615369 0 322942 0 0 0 0 0 173291 306634 0 278223 1057349 404798 203076 299776 185618 0 247760 0 231638 0 0 0 0 0 235646 295806 403670 0 307192 258281 0 0 0 181901 0 256608 184212 0 0 0 0 0 0 0 0 0 0 0 262360 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111006 0 0 0 0 0 0 0 223932 0 0 0 0 0 259360 135883 0 168497 658025 224715 141954 234971 250771 0 0 0 252079 0 0 0 0 0 145152 443744 217475 0 217564 147089 230055 0 0 255448 0 101407 157886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184774 0 0 0 0 0 0 199265 0 0 0 0 0 0 0 0 0 146896 0 0 -AAEAAAQAQNEK MGYG000004748_01973;MGYG000000013_03125;MGYG000004019_01965;MGYG000000098_01923;MGYG000001661_00289;MGYG000000196_04115;MGYG000002281_00036;MGYG000000054_01911;MGYG000002549_00068;MGYG000001313_03010;MGYG000003351_04331;MGYG000001378_03174;MGYG000002455_03725;MGYG000000105_01451;MGYG000003681_01202;MGYG000001337_04184;MGYG000000236_02897;MGYG000003922_01651;MGYG000000029_01174 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0845@1|root,COG0845@2|Bacteria,4NECC@976|Bacteroidetes,2FMDD@200643|Bacteroidia,4ANZR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Auxiliary transport protein, membrane fusion protein (MFP) family protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01993 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 400954 305328 423683 574068 0 350257 0 494092 720664 678098 305483 834740 267174 0 632553 474716 521071 0 0 616170 503638 457240 0 517853 515541 692409 0 0 508942 658780 0 0 528343 721412 0 461519 366653 306380 889906 558481 786568 1154319 0 966078 0 1239580 1101435 1499598 1432987 1013823 542965 0 1019842 716719 974419 0 0 1005927 1010217 1253856 0 817394 1020301 1272666 0 0 1033501 1150941 0 0 518969 850055 0 757237 1150916 788377 352042 546442 651895 564606 0 738384 0 553419 638428 552357 529327 643297 523136 0 0 535369 577191 0 0 473139 692647 474359 0 558050 446767 502327 0 0 519215 501666 0 0 429323 612919 0 799959 689250 617221 672775 580553 608184 492224 0 617297 0 645936 532164 500153 469847 617661 538545 0 525761 579325 636645 0 0 585758 362865 496537 0 553155 889418 1058603 0 0 627811 470806 0 0 530249 529795 0 451285 670528 525997 734838 328089 544435 665549 0 528928 0 592373 798858 502516 921153 569160 829476 0 635908 555762 439199 0 0 687417 491380 631045 0 433257 734751 1007775 0 0 541245 621345 0 0 0 574207 0 812371 742144 398934 -AAEAAGADIVGDDELIAK MGYG000001300_02637 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3WH4A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575296 0 0 0 0 0 0 0 0 0 373316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1734177 0 0 0 0 0 0 0 0 0 1507987 0 0 0 0 1529449 1867408 0 1556005 0 0 0 0 0 0 0 0 0 2094604 0 0 0 0 0 0 0 0 0 236608 0 0 0 0 0 0 0 0 0 162183 0 0 0 0 0 0 0 348551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAAGAQEVGDDDLIAK MGYG000003937_00914;MGYG000003921_01312;MGYG000004732_01000;MGYG000001157_02092;MGYG000000573_00679;MGYG000000084_00770 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3WH4A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1045893 1135759 977431 928074 1057513 1128796 891803 1371493 1149624 1375254 1228860 1651684 1600146 1150949 1154279 1321587 1218578 2538183 1200440 1240298 1183466 956456 1681487 982532 1322685 1177011 1004363 1942382 1405820 1078508 878885 1157088 595069 1092025 1299216 1063085 844956 804342 0 0 0 304890 0 97968 244644 0 238471 144980 148357 1419969 0 0 0 0 0 1178405 0 0 0 0 1461816 0 116444 0 0 1779479 0 1102961 0 0 0 0 237736 0 0 0 0 0 232875 0 0 0 0 0 545567 232482 302362 2946773 413592 318194 213557 0 473267 383935 0 292539 524354 0 289884 155981 560931 186367 395609 561499 0 0 543406 0 291837 276938 539626 423996 226518 0 439520 621890 588665 554566 490592 487643 649099 529885 513707 524814 416000 1560555 1003807 420531 559930 439987 397269 1584248 426991 466482 362763 517505 1334968 639330 576004 355362 500246 2178087 685577 782261 769597 457577 620073 203601 585951 0 0 616631 505761 609095 470892 632582 412197 434458 338315 782425 419617 208074 261632 1771913 619281 674828 498883 594527 692732 1946974 431238 304405 735560 479868 2423613 548624 559970 493132 549201 2887168 498993 718434 451420 459571 611445 615914 765982 599177 557835 560145 -AAEAAKAGAESTK MGYG000001617_03554 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp900547735|m__MGYG000001617 1.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Dihydroxyacetone kinase 1.0 dhaK 1.0 - 1.0 2.7.1.28,2.7.1.29,4.6.1.15 1.0 ko:K00863 1.0 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 1.0 M00344 1.0 R01011,R01059 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak1,Dak2,SDH_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triokinase. | glycerone kinase. | FAD-AMP lyase (cyclizing). triose kinase. | dihydroxyacetone kinase. | FMN cyclase. While FAD was the best substrate tested the enzyme also splits ribonucleoside diphosphate-X compounds in which X is an acyclic or cyclic monosaccharide or derivative bearing an X-OH group that is able to attack internally the proximal phosphorus with the geometry necessary to form a P=X product; either a five-atom monocyclic phosphodiester or a cis-bicyclic phosphodiester-pyranose fusion.-!-The reaction is strongly inhibited by ADP or ATP but is unaffected by the presence of the product, cFMN. ATP + D-glyceraldehyde = ADP + D-glyceraldehyde 3-phosphate + H(+). | ATP + dihydroxyacetone = ADP + dihydroxyacetone phosphate + H(+). | FAD = AMP + H(+) + riboflavin cyclic-4',5'-phosphate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RIG-I-like receptor signaling pathway;Glycerolipid metabolism;Metabolic pathways;Fructose and mannose metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 872229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAALQEAEQR MGYG000004271_01972;MGYG000000271_02740;MGYG000000404_01863 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0457@1|root,COG0457@2|Bacteria,1TY3C@1239|Firmicutes,248IE@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Psort location Cytoplasmic, score 1.0 SpoVK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_19,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAAQEVIEDTAEEEQPAEQTAQ MGYG000001300_00870 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,3WKHQ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 206539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213073 0 1888177 1859480 0 0 1417916 0 0 0 0 0 961546 0 0 0 0 0 0 0 0 0 857318 0 1299324 0 0 0 0 0 0 0 0 2113119 0 0 0 0 2142537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAAYTGSQEPVEEMR MGYG000002438_01051 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,22VY5@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 924834 0 0 0 0 0 0 0 0 1114665 0 0 0 0 0 0 0 0 1081462 0 0 0 0 0 0 0 0 -AAEAAYTGSQEPVEEMRK MGYG000002438_01051 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,22VY5@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1441422 0 0 0 0 0 0 0 0 1296050 0 0 0 0 0 0 0 0 -AAEAAYTGTQAPVEEM(Oxidation)R MGYG000004823_01604;MGYG000002560_01853;MGYG000003693_02599;MGYG000002933_02482;MGYG000004748_02763;MGYG000002291_02904;MGYG000000781_00145;MGYG000001306_02803;MGYG000001835_00632;MGYG000002218_00765;MGYG000000243_01798;MGYG000004797_00034;MGYG000002171_02995;MGYG000002470_03292;MGYG000000042_00902;MGYG000003681_03182;MGYG000001787_02392 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAAYTGTQAPVEEMR MGYG000004823_01604;MGYG000002560_01853;MGYG000003693_02599;MGYG000002933_02482;MGYG000004748_02763;MGYG000002291_02904;MGYG000000781_00145;MGYG000001306_02803;MGYG000001835_00632;MGYG000002218_00765;MGYG000000243_01798;MGYG000004797_00034;MGYG000002171_02995;MGYG000002470_03292;MGYG000000042_00902;MGYG000003681_03182;MGYG000001787_02392 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 1048409 1192450 3377838 1427018 1887757 1321728 1452487 943416 984489 778588 1005215 965258 3053606 925540 633031 1936485 1154281 1061760 1007971 907236 1069850 812689 1461177 1195208 874781 755389 1165026 1542822 0 1149049 2098095 1321940 2945816 864076 997416 1063402 833775 3204802 935180 747064 980458 1227842 1644218 880560 823545 1044878 756576 900593 1474555 1012593 3626941 1164776 1065340 2738382 861558 2052345 695274 854168 916836 1078584 3018083 776988 965456 1041508 914103 2008464 0 972748 878078 1298125 978734 932078 932833 1055527 956426 801815 405325 0 530404 538290 835994 516310 770466 332171 751864 372697 648998 587616 1463018 577119 486828 880165 408146 1205823 534849 418655 425866 459933 1026643 573687 470838 448027 360231 831725 0 354886 707631 0 217066 0 534291 796529 584413 586252 195952 0 0 0 0 575169 238810 0 0 0 0 540347 408909 0 0 327195 210866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431642 377555 0 0 0 0 640788 460703 186387 776211 1133921 943375 664008 575313 794919 267333 598689 831433 2832961 520565 679485 2387479 711280 2038882 592107 970977 454567 570061 1851236 1179914 985213 842917 631143 1644539 0 959948 913494 698217 531941 599131 805010 135668 1092246 708036 -AAEAAYTGTQAPVEEMRK MGYG000003693_02599;MGYG000000243_01798;MGYG000002171_02995;MGYG000003681_03182;MGYG000001306_02803 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 3208138 0 1086889 0 0 0 0 0 0 0 0 0 0 0 0 314032 0 0 0 0 387720 0 0 0 0 504260 0 0 1733894 0 3136881 0 0 0 0 2221820 0 0 472208 0 488249 0 0 0 0 0 0 0 0 0 0 0 0 863360 0 0 0 0 1276602 0 0 0 0 1003540 0 0 299514 0 381888 0 0 0 0 409576 0 0 152558 0 523676 0 0 0 0 0 0 0 0 0 0 0 0 545247 0 0 0 0 392532 0 0 0 0 461332 0 0 370636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 558311 0 0 0 0 0 0 0 0 0 0 0 0 385434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAAYTGTQEPVKEMQK MGYG000002549_04026;MGYG000002281_04838 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314919 0 0 1198481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 665413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 895844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAAYTGTQVPVEEMR MGYG000001346_02469 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 618857 316746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247201 676586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1093633 442954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355773 240005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1660733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAAYTLDQGAVEEMR MGYG000003697_01979;MGYG000002834_01610 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1108004 0 0 762349 0 0 0 0 820484 0 0 0 0 0 0 1172966 0 0 0 1306782 1410299 1119915 0 0 0 989841 0 0 0 0 946731 0 0 0 0 617885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEADAIVTIGGGSSMDTAK MGYG000003266_00960 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900762015|m__MGYG000003266 1.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CV1A@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 - 1.0 - 1.0 1.1.1.1,1.1.1.77 1.0 ko:K00001,ko:K00048 1.0 ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00623,R00754,R01781,R02124,R02257,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 1.0 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | lactaldehyde reductase. aldehyde reductase. | propanediol oxidoreductase. Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | (1) (R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + H(+) + NADH. (2) (S)-propane-1,2-diol + NAD(+) = (S)-lactaldehyde + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Microbial metabolism in diverse environments;Glyoxylate and dicarboxylate metabolism;Fatty acid degradation;Chloroalkane and chloroalkene degradation;Metabolic pathways;Biosynthesis of secondary metabolites;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Drug metabolism - cytochrome P450;Metabolism of xenobiotics by cytochrome P450;Propanoate metabolism;Retinol metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 691572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEADC(Carbamidomethyl)IVTIGGGSSMDTAK MGYG000000084_00896;MGYG000000573_01786;MGYG000000022_00774;MGYG000003166_01233;MGYG000002545_02393;MGYG000003921_01948 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHER@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 fucO 1.0 - 1.0 1.1.1.77 1.0 ko:K00048 1.0 ko00630,ko00640,ko01120,map00630,map00640,map01120 1.0 - 1.0 R01781,R02257 1.0 RC00087,RC00099 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lactaldehyde reductase. propanediol oxidoreductase. - (1) (R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + H(+) + NADH. (2) (S)-propane-1,2-diol + NAD(+) = (S)-lactaldehyde + H(+) + NADH. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Propanoate metabolism;Glyoxylate and dicarboxylate metabolism 1.0 none 1.0 0 0 326941 357263 0 309090 156191 0 0 0 512738 0 0 0 0 0 0 859616 440296 0 0 207966 950184 566855 0 522517 0 1206962 0 0 324351 0 326735 398897 0 368110 365311 373632 690477 0 699047 724619 0 801934 945531 0 0 0 508583 743450 0 0 0 0 893640 976017 787234 0 0 375164 1291062 610067 941545 628397 0 1154168 0 0 612772 0 733360 547671 0 631533 638742 349470 0 0 0 0 0 496692 500277 0 0 0 322820 260006 0 0 0 0 0 1878280 406756 0 0 0 1713776 0 0 272873 0 1749497 0 0 554118 0 0 537868 0 523090 392293 603932 581935 0 686496 458404 0 800876 704791 0 0 0 323637 712372 0 0 0 0 464409 1912087 444211 0 0 519187 2147568 639139 482273 512301 0 1302925 0 0 574636 0 664392 614019 0 384996 745711 533596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1287065 0 0 0 0 1735215 0 0 162141 0 1695706 0 0 0 0 280238 0 0 0 0 0 -AAEAEAAR MGYG000002775_01690;MGYG000003266_00923 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0254@1|root,COG0254@2|Bacteria,2HUWQ@201174|Actinobacteria,4CVW5@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Binds the 23S rRNA 1.0 rpmE 1.0 - 1.0 - 1.0 ko:K02909 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L31 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 148076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAEADAAK MGYG000000003_00520 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1495589 782210 569642 1935302 0 983819 1577222 0 2402666 1425431 434278 1246578 0 1277297 0 0 0 0 2401585 1711223 2001888 897348 0 966114 1911592 2137036 0 0 1263621 1925820 0 791906 690033 0 1197004 1947617 1578480 436627 940556 498572 1007872 1263278 0 826575 1070545 0 907582 1064461 785793 0 0 1192865 0 0 0 0 1076195 814453 779618 825571 0 979234 896826 1247793 0 0 858042 926667 0 944562 420307 510531 759908 743861 920046 726987 795839 660385 949625 911860 0 406658 647755 0 949479 817333 583019 699648 0 698894 0 0 0 0 1255340 1494923 1604437 452671 0 544457 949452 752744 0 0 878091 1000053 0 440929 1034649 2008655 957723 1650299 1132210 955707 632147 699596 564285 890482 0 479253 971855 0 744616 610845 785988 927666 0 0 0 0 0 0 839057 803540 358372 518208 0 596305 785180 899428 0 0 663209 542018 0 525030 392533 869729 630850 300846 0 594894 0 299699 0 0 0 0 140054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88897 0 0 0 0 473398 0 0 0 -AAEAEAETIEDTSAQEA MGYG000002926_00849 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,2N7Q1@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341889 0 0 0 0 0 254641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 860862 0 754190 0 0 0 0 0 750278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAEAPAEEAAEAEK(Xlink_BuUrBu[111][K](Nmethylmaleimide)AE MGYG000002469_01742 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium breve|m__MGYG000002469 1.0 COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4D0PZ@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Ribosomal protein L17 1.0 rplQ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 1.0 - 1.0 ko:K02879 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 619865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAEIPVFTVDR MGYG000003383_00664 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium scardovii|m__MGYG000003383 1.0 COG1879@1|root,COG1879@2|Bacteria,2GJ0Z@201174|Actinobacteria,4D2SP@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K02058,ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212,M00221 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 590950 0 0 0 0 646350 0 0 0 0 601500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6600680 0 0 0 0 1891990 0 0 0 0 4818935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309600 0 0 0 0 0 0 0 0 0 1309439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAEKTEDAE MGYG000000022_01173;MGYG000000195_01312 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332067 0 0 184876 0 1092521 0 0 0 0 1742774 0 0 0 0 2164881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381140 412433 0 356785 0 341094 0 0 0 0 984536 0 0 0 0 1714308 0 0 382669 0 0 585748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75967 0 0 0 0 499035 0 0 0 0 0 0 0 0 0 550773 0 0 209489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343622 229949 0 247997 0 2443835 0 0 0 0 3235536 0 0 0 0 1407632 0 0 393018 0 0 200537 0 0 0 0 -AAEAEKTEDAQ MGYG000002545_00080 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_G|m__MGYG000002545 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1793453 0 0 0 0 1233524 0 0 0 0 1826159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15454 0 0 0 0 135420 0 0 0 0 422277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335537 0 0 0 0 279337 0 0 0 0 158777 0 0 0 0 0 0 0 0 0 0 -AAEAEVDALVK MGYG000003683_01140 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1248309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2674209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2877135 0 805862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732931 0 0 0 0 0 0 0 0 0 0 0 0 1094550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1030568 0 0 0 0 0 0 0 0 0 0 1161728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAFAELLK MGYG000002455_04253 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG0614@1|root,COG0614@2|Bacteria,4NGP1@976|Bacteroidetes,2FNKG@200643|Bacteroidia,4AMD2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1818694 0 0 0 0 1261539 0 0 0 0 1486335 0 0 0 0 0 0 0 0 0 0 -AAEAIGK MGYG000001157_01952 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540775|m__MGYG000001157 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94679 0 0 0 0 49064 0 0 0 0 1307075 0 0 0 0 0 0 0 0 0 0 -AAEAIGKGLAASPGSAC(Carbamidomethyl)GR MGYG000000084_02524;MGYG000004732_02304 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEALKER MGYG000002515_01689;MGYG000003372_04360;MGYG000002494_03245;MGYG000002477_02881 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,3XP2G@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) 1.0 prs 1.0 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEALLLTK MGYG000000133_00484;MGYG000002966_02815 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1142@1|root,COG1142@2|Bacteria,1VCTD@1239|Firmicutes,24EHU@186801|Clostridia,25XTU@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 4Fe-4S dicluster domain 1.0 - 1.0 - 1.0 - 1.0 ko:K05796 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Fer4,Fer4_10,Fer4_3,Fer4_4,Fer4_6,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 662588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1041999 0 0 0 0 306641 -AAEAPAAEAKPARK MGYG000000022_00261 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 2BACE@1|root,323SU@2|Bacteria,1UH7E@1239|Firmicutes,257YA@186801|Clostridia,3WKG9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 51275 0 0 0 0 151623 0 0 0 0 120195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144798 0 0 0 0 225307 0 0 0 0 213785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEASLMSAR MGYG000000196_03104;MGYG000001378_04950 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,2FND5@200643|Bacteroidia,4AKYA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 MU 1.0 Efflux transporter, outer membrane factor lipoprotein, NodT family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OEP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEASYQANDEVNALK MGYG000000243_03195 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF4@976|Bacteroidetes,2G3EZ@200643|Bacteroidia,4APQM@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754578 0 0 0 0 0 0 0 1095062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEATK(Lys->Gln)LFVEGK MGYG000001300_00595 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,3WJGA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2007068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2501939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10051390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEATQLFVEGK MGYG000000022_00316 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,3WJGA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 2028396 0 0 1684662 0 0 0 0 0 0 0 0 0 0 0 2775062 0 1255752 0 0 2425771 0 0 1435546 1402869 2520753 0 0 0 1414906 0 0 0 0 0 1453569 3426313 0 2486460 0 0 2908400 0 0 0 0 0 0 0 0 0 0 0 9662987 0 3142161 0 2650514 8761213 2912245 0 2999689 3245683 9285551 0 0 1872957 3091240 2599760 0 0 0 3585699 2338077 2843698 0 1650122 0 0 2285598 0 0 0 0 0 0 0 0 0 0 0 9318118 0 1720685 0 2941827 0 2380164 0 3254438 2433678 12690592 0 0 2562355 2865229 2057713 0 3342741 0 3267993 2572692 0 0 2744649 0 0 3436892 0 0 0 0 0 0 0 0 0 0 0 2673567 0 1429292 0 3304881 3174663 0 0 912877 886292 3705959 0 0 2317599 1883176 1906445 0 1160791 0 0 2831173 955495 0 0 0 0 561136 0 0 0 0 0 0 0 0 0 0 0 1604521 0 576050 0 939720 584029 0 0 773875 0 620909 0 0 1060204 674714 944428 0 298675 0 295676 793815 -AAEAVAAVEPGK MGYG000002557_00596;MGYG000004875_00024;MGYG000002050_01271;MGYG000000188_00828;MGYG000003073_01053;MGYG000004396_00611;MGYG000004746_01527;MGYG000001636_00874;MGYG000003274_01602;MGYG000003851_00622;MGYG000004681_01192;MGYG000002919_00267;MGYG000002775_01123;MGYG000002970_00370;MGYG000000802_01544 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CUGT@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 650672 4222079 641619 347983 0 711637 205919 1014289 449726 989061 1548404 1053278 2721318 0 1251591 3162222 536359 2039732 719889 923165 776738 839388 1131640 0 0 484358 477526 1501311 1186006 592781 619040 0 553557 0 646420 507452 557971 545127 897853 774722 363861 744006 0 444154 832539 826749 666109 524991 1474494 591049 1159080 0 268359 653904 371293 1909550 615450 845487 484323 0 1054833 797464 0 601746 776505 1753420 941200 582709 1068792 0 0 0 481712 1050409 880057 405060 1139286 1334015 275704 696916 0 319267 812534 1088531 500921 940660 648543 534685 1559851 0 1149733 2000023 1793509 349310 1034682 1165184 926875 1188451 859856 0 0 884296 1130064 1036375 842395 803928 365976 0 1060264 0 667851 384485 688095 484122 975120 1595754 1393663 1757578 0 1287690 1460319 623184 934041 1719135 5160820 1445803 6525824 0 0 9049002 2131925 1300058 785372 1753193 672526 3161518 388114 2465558 0 0 858673 2505913 4817415 2579103 2089615 0 1435688 0 514853 903773 381465 2205957 0 362825 0 605017 0 0 0 0 0 0 696384 0 0 0 0 161197 0 0 271538 0 0 0 159584 0 0 0 0 521326 529686 0 0 0 372032 0 0 0 0 0 -AAEAVAAVEPGKVLVLENVR MGYG000001636_00874;MGYG000002919_00267;MGYG000001718_00620;MGYG000002775_01123;MGYG000002050_01271;MGYG000000188_00828 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CUGT@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 377780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAVN(Deamidated)GSLSGTK MGYG000000077_01499;MGYG000000262_00355 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG3087@1|root,COG4577@1|root,COG3087@2|Bacteria,COG4577@2|Bacteria,1VEIA@1239|Firmicutes,24JTP@186801|Clostridia,25XFB@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 872860 971155 829712 466535 0 1112276 0 955090 740632 934681 676511 0 980896 941364 1109061 1117799 618999 0 1239479 1091581 585235 1229033 0 272146 2173760 422422 265864 0 0 503558 0 994935 164016 627041 344832 0 409748 572542 744245 868259 212194 459635 0 599827 1351405 481338 635258 451558 194183 0 411485 419496 456936 150031 390756 0 603795 776294 127763 282488 0 840830 504669 510549 581871 0 0 226364 0 381650 318597 686065 726560 0 771465 296131 2705065 3072187 586251 3017121 0 813962 684131 2281380 914608 2157458 473482 0 1778643 794004 2350299 2022363 1894162 0 2915375 2672608 1951456 3019117 0 1176425 2752865 1731091 2882371 0 0 1585301 0 2202698 1376017 2340546 2544378 0 1702861 693154 1288775 1377926 934669 882347 0 1680864 2021929 1130887 1018178 1776321 948387 0 1226685 1498163 850780 1942939 1411475 0 617792 1710604 497782 1587794 0 1056957 867371 521297 1310011 0 0 1358628 0 671060 1208791 601444 1389410 0 961567 836947 1004561 1425935 1644230 755196 0 1067830 860087 1091697 1067738 1308730 1343676 0 1771117 985640 1221724 1676809 933392 0 987789 998121 810842 1264865 0 713926 1277841 1251222 779874 0 0 964491 0 1238540 1525874 1193152 67263 0 1482072 1359804 -AAEAVNGSLSGTK MGYG000000077_01499;MGYG000000262_00355 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG3087@1|root,COG4577@1|root,COG3087@2|Bacteria,COG4577@2|Bacteria,1VEIA@1239|Firmicutes,24JTP@186801|Clostridia,25XFB@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 510418 646869 451362 0 0 724503 0 0 0 0 600532 0 1067539 0 445259 1102238 0 0 0 571206 579109 1137112 0 227748 0 504762 0 0 419869 0 0 480275 0 0 0 0 378978 555777 666276 500377 0 433084 0 0 0 0 0 0 0 0 0 0 221683 0 0 0 0 485067 110688 0 0 612369 0 201270 0 0 532956 0 0 116177 0 0 0 0 210067 595857 1561567 1957869 666116 2291776 0 1437595 0 0 0 0 1278332 0 1062866 0 1913349 1363137 0 0 0 2195729 1503967 2081942 0 1147686 0 1614759 0 0 1003457 0 0 1081071 1268582 0 0 0 1259769 872007 909888 848669 782782 1102709 0 928012 0 0 0 0 764579 0 899150 0 658447 1366241 0 0 0 1212370 415975 878543 0 860118 0 0 0 0 823887 0 0 714777 1018582 0 0 0 0 953771 0 1413178 994752 699565 0 858860 0 0 0 0 980691 0 1213875 0 465526 1240747 0 0 0 1246576 0 946836 0 697208 0 959883 0 0 199640 0 0 957435 1107588 0 0 0 825132 873312 -AAEAYFLLAEAK MGYG000002478_01404;MGYG000004797_04332 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2513704 2841745 2927951 2871290 2006747 2241182 3295133 1812232 2747020 2019244 2741024 2615209 1835897 2116001 1561793 2935493 2553017 0 2553551 2178916 2191908 2196917 0 3133315 2449494 2669159 2388285 0 3415768 2502734 5289368 3496486 2726058 961172 3616019 3086318 2617688 2290236 469370 659308 834100 389650 732152 910189 903066 453830 557791 768286 499666 714394 0 790291 1183722 617128 320436 0 813723 733683 875241 901213 0 590231 843962 1219193 754410 0 584207 207918 716646 862902 494411 189478 956546 715703 574175 417119 0 1322857 2230784 1820982 2917198 2389545 2251890 1467873 1806729 1854922 1953734 2345396 1046421 2274068 1310279 1552924 663052 0 2077284 1513647 1624761 1324088 0 2477356 1707359 1833359 1895907 0 1993639 1534524 2721605 1494116 1774475 809433 1702290 2033977 1720725 2060053 702232 552438 743789 422977 601022 658626 660758 782952 604886 819501 211175 728389 378351 741819 621870 530073 256780 0 941254 689612 905434 572634 0 557386 799744 1001652 812362 0 581313 776714 700709 628661 737669 508269 677284 888446 925380 530951 2115833 1892291 1583470 1811461 2670582 2861550 1940168 2689680 2512571 889394 1576638 1445639 1280169 1412741 1648639 1739511 2023991 0 2408672 3177631 1634670 2177184 0 1628474 2284507 2041974 1913574 0 2007499 3016440 2164565 2251831 1209182 2533153 2906367 1671538 2344192 2177030 -AAEAYLNFAEADAR MGYG000003697_02405 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,2FNRM@200643|Bacteroidia,4AKT2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 367999 0 473559 0 289169 0 361912 628375 0 0 0 0 0 0 0 0 0 397866 0 0 0 0 332752 0 608443 0 0 448470 0 0 0 0 243281 463035 0 0 335618 307522 1002627 0 127279 0 242473 0 0 1819477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675544 0 1002505 204482 0 0 0 0 0 1352267 550789 0 0 0 1522232 202267 902625 0 0 0 596701 0 967098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436626 553207 0 0 0 0 0 742093 0 0 0 0 0 0 1451519 0 1063751 0 2950777 0 1215188 1500659 0 0 0 0 0 0 0 0 0 8171745 0 0 0 0 14345240 0 1227973 1402688 0 8450781 0 0 0 3212963 650787 1369608 0 0 1504336 1759896 2265753 0 2818626 0 1865402 0 79914 3565555 0 0 0 0 0 0 0 0 0 9142226 0 0 0 0 237417 0 2879814 0 0 195217 0 0 0 172930 2769379 6656582 0 0 0 6989779 -AAEAYLNYIEAC(Carbamidomethyl)YEK MGYG000000243_00118 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0457@1|root,COG0457@2|Bacteria,4NG3F@976|Bacteroidetes,2FM0I@200643|Bacteroidia,4AKP7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 695855 0 1421237 887613 948471 601561 1096435 812875 919085 0 0 0 731828 0 0 0 678887 453987 726400 0 0 373565 653790 948819 0 692167 0 449863 0 0 1967419 1128751 1916324 907301 0 778427 663122 1583928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3488460 0 0 0 0 0 0 0 0 0 0 421218 312054 197446 0 0 0 0 0 373738 0 0 0 0 270590 232809 0 0 0 0 0 0 0 0 318493 0 0 298741 831815 0 0 0 0 0 328700 0 0 376882 0 574091 256672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34204 0 0 166699 0 0 0 0 0 0 0 0 0 0 0 0 247752 0 0 28531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30130 0 0 0 0 0 0 0 0 0 0 0 0 -AAEAYR MGYG000002492_00917;MGYG000000262_02232;MGYG000000077_02465;MGYG000000076_01479 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,25UX1@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.75 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1027163 0 0 0 0 0 0 0 0 0 0 0 997090 0 0 0 0 0 0 0 1012480 0 0 1357755 0 0 0 0 0 826331 0 0 0 0 1291333 0 0 0 1439136 0 0 0 0 0 1258112 0 1309548 0 0 0 0 880069 0 0 0 1626464 1415475 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3308386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1279258 0 0 0 0 0 -AAEC(Carbamidomethyl)AVIVGNAK MGYG000002720_00009 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes 1.0 1239|Firmicutes 1.0 J 1.0 elongation factor G 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 597205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517238 0 0 0 0 0 0 0 0 0 0 654502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227064 0 338762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEDAFTSR MGYG000004797_02944 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 535480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEDFAVGNVVK MGYG000000184_00844;MGYG000001338_01638 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3XZ91@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 9.98 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Ribosome;Metabolic pathways;Biosynthesis of secondary metabolites;Terpenoid backbone biosynthesis 1.0 none 1.0 0 1032571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1499816 0 0 0 0 0 0 0 1815799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1022586 0 0 0 0 0 0 0 1459758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1522672 0 0 0 0 0 0 0 4122914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1299425 0 0 0 0 0 0 0 2260280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2999873 0 0 0 0 0 0 -AAEDFDDSAFGR MGYG000003683_01773 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CYYS@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 3.2.1.23 1.0 ko:K01190 1.0 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 1.0 - 1.0 R01105,R01678,R03355,R04783,R06114 1.0 RC00049,RC00452 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,RicinB_lectin_2 1.0 3.2.1.23 1.0 GH2 1.0 GH2 1.0 GH2 1.0 beta-galactosidase. lactase. Some enzymes in this group hydrolyze alpha-L-arabinosides; some animal enzymes also hydrolyze beta-D-fucosides and beta-D-glucosides (cf. EC 3.2.1.108). Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D- galactosides. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Other glycan degradation;Sphingolipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1071539 0 0 0 0 162574 0 0 0 0 857228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEDGAAAAPAQS(Deoxy[S](Ser->Ala)EPK MGYG000002517_01392 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 Signal transducing histidine kinase homodimeric 1.0 cheA 1.0 - 1.0 2.7.13.3 1.0 ko:K03407 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW,H-kinase_dim,HATPase_c,Hpt,P2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 histidine kinase. protein kinase (histidine). This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine).-!-A number of histones can act as acceptor. ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 437560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417239 0 0 0 0 0 0 0 0 0 0 196602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726434 0 0 941392 0 0 0 0 1022521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 785195 0 0 0 0 0 0 0 0 0 0 1039711 0 586192 0 0 694161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEDLFLGR MGYG000001378_03057 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,2FNEA@200643|Bacteroidia,4AKUK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins 1.0 ftsH 1.0 - 1.0 - 1.0 ko:K03798 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000,ko01002,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,FtsH_ext,Peptidase_M41 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 853066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 821258 1008402 0 0 0 0 0 0 0 0 0 0 0 482006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287071 0 0 0 0 0 0 0 0 0 0 0 0 437250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271552 274447 0 0 0 0 0 298341 0 0 0 0 0 570105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEDMELK MGYG000000254_03300 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Marinifilaceae|g__Odoribacter|s__Odoribacter splanchnicus|m__MGYG000000254 1.0 COG5010@1|root,COG5010@2|Bacteria,4PMJW@976|Bacteroidetes,2G0E2@200643|Bacteroidia,2326G@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_19,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 1169181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974794 0 0 0 0 0 0 0 0 0 0 449725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366117 0 0 0 0 0 0 0 0 0 0 506651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 636496 0 0 0 0 0 0 0 0 0 0 145025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545483 0 0 0 0 0 0 0 -AAEDRENQIR MGYG000000164_01314 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3XYH6@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 1207912 0 0 1164923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEDVNKQELK MGYG000000196_00497 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 2F08Y@1|root,33TCA@2|Bacteria,4NTB5@976|Bacteroidetes,2FRQT@200643|Bacteroidia,4AT8I@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Fibronectin type 3 domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BACON,F5_F8_type_C 1.0 - 1.0 - 1.0 - 1.0 CBM0 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1376652 1464428 1283211 1747857 0 0 1853465 1664276 1640436 1449599 824601 0 0 1690181 0 0 1317171 0 0 1371009 0 0 0 0 1671795 1678488 1529904 0 3144037 0 0 2054598 1275272 2305362 1660585 1716008 1823700 1074775 1572559 1743601 1516195 1800131 0 0 2403185 2332318 1337043 2395047 1950911 0 0 2757382 0 0 2052857 0 0 2005090 0 0 0 0 1900710 2177301 2274798 0 2051388 0 0 2435012 1721301 2529005 2141507 1899307 2293047 1937742 789361 1124129 1046766 942025 0 0 1244638 1331478 1600206 592798 869227 0 0 1177409 0 0 717128 0 0 1035415 0 0 0 0 1083414 1111814 987911 0 1470906 0 0 1111383 809612 1269877 1261331 1388073 1068978 898927 76728 674418 585867 673597 0 0 578693 677116 663765 518984 309844 0 0 429908 0 0 432126 0 0 465280 0 0 0 0 584080 695870 453591 0 743927 0 0 658052 656681 997524 740319 916026 1204428 661390 901680 600742 681220 1006328 0 0 993401 1135897 832757 844085 811634 0 0 748001 0 0 740422 0 0 1292870 0 0 0 0 1050611 1268249 689614 0 142443 0 0 477303 561862 1247346 1131778 1004846 1479760 959587 -AAEEAGLDLVK MGYG000003166_00981 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539885|m__MGYG000003166 1.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,3WIZW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins 1.0 infC 1.0 - 1.0 - 1.0 ko:K02520 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 IF3_C,IF3_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1627952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1088769 0 0 0 0 0 0 0 0 0 0 0 0 1022375 0 0 2574001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2841996 0 0 0 0 0 0 0 2841245 0 0 0 0 2231533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 693849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 980473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423473 -AAEEALAAEQLK MGYG000000262_00560 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0305@1|root,COG0305@2|Bacteria,1W6Y2@1239|Firmicutes,25M5M@186801|Clostridia,25ZAD@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 L 1.0 Participates in initiation and elongation during chromosome replication 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DnaB_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1282941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1390085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1103323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 720128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEEAPAAPPAPPAPTKEEVLLTEIR MGYG000000196_00480 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,2FT2E@200643|Bacteroidia,4AQQ5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell 1.0 mscL 1.0 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 1.0 - 1.0 ko:K03282 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.22.1 1.0 - 1.0 - 1.0 MscL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 448598 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 567207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEEAPAEEAPAEA MGYG000002293_01607 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1963902 0 0 0 0 2095798 0 2079117 0 0 1077689 0 0 0 0 0 0 0 2069750 0 0 0 0 0 0 0 935819 2084151 0 0 0 0 2036727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEEDRHEFVR MGYG000000187_00889 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,25V03@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family 1.0 glgD 1.0 - 1.0 2.7.7.27 1.0 ko:K00975 1.0 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 1.0 M00565 1.0 R00948 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Hexapep,NTP_transferase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-1-phosphate adenylyltransferase. ADP-glucose synthase. - alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Biofilm formation - Escherichia coli;Metabolic pathways;Starch and sucrose metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 870331 0 0 0 0 787864 0 0 0 0 752627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166066 0 0 0 0 100136 0 0 0 0 179157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 235665 0 0 0 0 0 0 0 0 0 0 -AAEEFR MGYG000000142_01470 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3XZ7P@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 - 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4583560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEEGDIAAR MGYG000003697_01726;MGYG000002960_00421 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,2FPKZ@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 F 1.0 Belongs to the SAICAR synthetase family 1.0 purC 1.0 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 6.3.2.6 1.0 ko:K01923 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04591 1.0 RC00064,RC00162 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 SAICAR_synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase. SAICAR synthetase. Forms part of the purine biosynthesis pathway. 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate + ADP + 2 H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5164940 0 0 0 0 0 0 0 0 0 0 0 0 1939614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEEGIADLK MGYG000003819_00854 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__UMGS1872|s__UMGS1872 sp900555795|m__MGYG000003819 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,2N697@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 1284440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 837782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEEGIEYTK MGYG000000077_00695;MGYG000000262_00844 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,24FUX@186801|Clostridia,25VQY@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 S 1.0 Dihydroxyacetone kinase, L subunit 1.0 dhaL 1.0 - 1.0 2.7.1.121 1.0 ko:K05879 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways 1.0 none 1.0 548534 1071657 557189 391847 0 1243351 129332 829078 0 864361 0 0 0 0 822513 1052614 0 0 735206 753538 707118 1142617 0 349444 961956 527175 302017 0 423987 0 843804 1019605 556800 749132 301506 0 353843 479837 1262425 1286879 682555 1014251 0 768217 1933904 931278 0 873472 0 0 0 0 658268 449552 0 0 944375 1203916 725283 742766 0 1633788 808143 995816 1026395 0 2384974 0 1019258 838154 714231 1152380 714587 0 1012223 703597 2349613 2984273 675627 2598100 0 1775363 1225972 2445346 0 2114336 0 0 0 0 2709011 1974067 0 0 2679096 2608525 1780965 2712758 0 1264840 2623787 2250707 2731728 0 525859 0 629193 2025322 1393126 3038643 2747724 0 1872265 571765 1552274 1861213 1157204 2002313 0 1668139 2323339 969525 0 1458779 0 0 0 0 1049493 2575324 0 0 1148796 2252631 653370 1352569 0 1348424 1280373 805695 1451483 0 1858023 0 1012143 1158473 1469111 734234 1051945 0 819307 1401856 346289 910328 1087322 887613 0 1146860 905368 533756 0 310123 0 0 0 0 289501 928912 0 0 743725 252204 549351 1397882 0 1277121 445069 325107 283219 0 238690 0 1595182 1135995 1512172 594366 321033 0 237913 859567 -AAEEIAAGR MGYG000002720_00404;MGYG000002794_01705;MGYG000002156_00381 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,4BWU3@830|Butyrivibrio 1.0 186801|Clostridia 1.0 C 1.0 NADH:flavin oxidoreductase / NADH oxidase family 1.0 - 1.0 - 1.0 1.3.1.31 1.0 ko:K10797 1.0 ko00360,ko01120,map00360,map01120 1.0 - 1.0 R02252 1.0 RC00669 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Oxidored_FMN,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-enoate reductase. enoate reductase. Acts, in the reverse direction, on a wide range of alkyl and aryl alphabeta-unsaturated carboxylate ions; 2-butenoate was the best substrate tested. butanoate + NAD(+) = (2E)-2-butenoate + H(+) + NADH. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Phenylalanine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1602811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1860172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEELFTGHISTGAMNDLER MGYG000000243_02615 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,2FNEA@200643|Bacteroidia,4AKUK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins 1.0 ftsH 1.0 - 1.0 - 1.0 ko:K03798 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000,ko01002,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,FtsH_ext,Peptidase_M41 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEELIFHSITTGASNDIEQATK MGYG000000142_02465 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XZ55@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins 1.0 ftsH 1.0 - 1.0 - 1.0 ko:K03798 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000,ko01002,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,FtsH_ext,Peptidase_M41 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 445073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822606 0 0 0 0 0 0 0 -AAEELNKR MGYG000002506_04803;MGYG000002515_02416;MGYG000003365.1_00759;MGYG000002494_00622;MGYG000003372_00502;MGYG000002535_03054 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,1RNC7@1236|Gammaproteobacteria,3XPHP@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Alkyl hydroperoxide reductase 1.0 ahpF 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008785,GO:0009321,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.0 - 1.0 ko:K03387 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 GIDA,Pyr_redox_2,Pyr_redox_3,Thioredoxin_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 65766 127036 0 27757 221225 0 134642 0 110758 0 0 0 0 0 0 0 0 0 0 0 214707 0 153339 0 0 0 0 0 0 0 0 51550 114278 0 0 0 80792 0 522002 624015 291886 666309 926316 0 332285 0 343558 0 0 0 0 0 0 0 0 0 0 0 1140473 0 1031441 0 0 0 0 0 0 0 0 337898 310103 0 0 0 322623 0 189679 252721 130880 168228 332428 0 186294 0 220032 0 0 0 0 0 0 0 0 0 0 0 312726 0 321423 0 0 0 0 0 0 0 0 283803 237809 0 0 0 191584 0 265644 182640 241408 208052 236340 0 163267 0 228550 0 0 0 0 0 0 0 0 0 0 0 317773 0 292014 0 0 0 0 0 0 0 0 162594 295496 0 0 0 225856 0 0 0 0 0 0 0 230994 0 36415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144845 0 0 0 0 38889 -AAEELR MGYG000000003_02003;MGYG000002203_00962;MGYG000003022_01479;MGYG000000258_00354;MGYG000003279_02141;MGYG000003022_01477;MGYG000001315_01431 domain d__Bacteria 1.0 COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,2G0KY@200643|Bacteroidia 0.42857142857142855 976|Bacteroidetes 0.42857142857142855 E 0.7142857142857143 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 0.42857142857142855 speA 0.42857142857142855 - 1.0 4.1.1.19 0.42857142857142855 ko:K01585 0.42857142857142855 ko00330,ko01100,map00330,map01100 0.42857142857142855 M00133 0.42857142857142855 R00566 0.42857142857142855 RC00299 0.42857142857142855 ko00000,ko00001,ko00002,ko01000 0.7142857142857143 - 1.0 - 1.0 - 1.0 Orn_Arg_deC_N,Orn_DAP_Arg_deC 0.42857142857142855 - 1.0 - 1.0 - 1.0 - 1.0 arginine decarboxylase. L-arginine carboxy-lyase. - H(+) + L-arginine = agmatine + CO2. 0.42857142857142855 0.42857142857142855 0.42857142857142855 0.42857142857142855 Metabolic pathways;Arginine and proline metabolism 0.42857142857142855 none 1.0 671341 649417 99066 980321 899132 584673 1773175 0 1130024 1049419 1437412 885962 808842 946486 1051556 1005984 870519 0 1049927 885895 1510282 1083679 0 0 1480594 908669 1129594 0 1112210 962543 1200841 748845 965134 860257 1515944 884694 802341 940658 4521559 3252613 4235428 5210142 4482318 4432813 3818618 11524658 3255768 5051521 6302097 6498023 4619782 5037073 4361750 5168183 5219026 0 7705417 3902029 3517329 4343630 0 4347326 4410054 5292482 5732917 0 4157418 3618715 4934116 4512188 2114854 4081931 8738141 3226684 3945345 3593297 1924143 2425654 2523251 2563436 2757089 2635610 2134698 4872500 2401651 2814539 2324103 2600119 2502999 2608298 3084089 2913360 3037757 0 3209090 3456776 3849223 3383842 0 8368501 3117346 3235944 2399278 0 2912508 1755167 2279596 2560989 2881496 3640871 7561491 3402462 2715887 2586922 775728 926865 1470600 687172 959905 1142518 1622420 796520 0 779421 975644 943268 435562 675664 191390 928575 755997 0 591664 458105 349241 742126 0 1420740 656406 750129 667608 0 873790 734887 1056831 901365 1189846 1411669 1099042 510811 801517 727324 0 873398 652054 247576 170918 883667 276042 734780 1040308 207717 386064 162030 0 371673 636571 145748 311621 0 198693 0 818545 355059 0 1257361 265888 323301 325124 0 412886 273238 601135 0 1980780 335836 798836 308593 311662 345029 -AAEELRDALYAK MGYG000003022_01479;MGYG000003022_01477 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella|s__Parasutterella sp000980495|m__MGYG000003022 1.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2W02M@28216|Betaproteobacteria,4PQCS@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 E 1.0 Fumarase C C-terminus 1.0 aspA 1.0 - 1.0 4.3.1.1 1.0 ko:K01744 1.0 ko00250,ko01100,map00250,map01100 1.0 - 1.0 R00490 1.0 RC00316,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FumaraseC_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate ammonia-lyase. fumaric aminase. - L-aspartate = fumarate + NH4(+). 1.0 1.0 1.0 1.0 Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 195118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 589596 513407 682747 0 1436457 786024 0 1447078 0 1404417 1258528 636459 1200365 751586 0 0 0 0 315968 0 0 1188946 0 447764 0 701572 825343 0 1487315 0 277520 0 1041708 0 1378704 853462 883356 460401 1288303 2601264 1763951 0 2278909 2624024 0 4766212 0 1790086 1906126 1699684 1937473 1478353 0 0 0 0 1577742 0 0 1527810 0 2328252 0 1002557 1025971 0 1786545 0 2163318 0 1059683 0 4751297 1375687 1045017 1716569 0 0 0 0 0 84315 0 240838 0 0 0 175830 0 62337 0 0 0 0 93669 0 0 0 0 0 0 343134 0 0 0 0 0 0 0 0 589960 108215 0 0 0 0 0 0 87359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70521 0 0 0 0 0 0 0 160479 0 -AAEELRDALYAKAK MGYG000003022_01479;MGYG000003022_01477 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella|s__Parasutterella sp000980495|m__MGYG000003022 1.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2W02M@28216|Betaproteobacteria,4PQCS@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 E 1.0 Fumarase C C-terminus 1.0 aspA 1.0 - 1.0 4.3.1.1 1.0 ko:K01744 1.0 ko00250,ko01100,map00250,map01100 1.0 - 1.0 R00490 1.0 RC00316,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FumaraseC_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate ammonia-lyase. fumaric aminase. - L-aspartate = fumarate + NH4(+). 1.0 1.0 1.0 1.0 Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 927997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEEQGLEAGSDEYK MGYG000002641_01217;MGYG000001300_01661;MGYG000003899_00099;MGYG000002651_02100 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,3WI31@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 ABC-type branched-chain amino acid transport systems periplasmic component 1.0 livK 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 1.0 none 1.0 551459 945077 808391 0 0 759861 542026 0 594006 0 622707 426569 1078229 0 0 997921 1120746 0 979807 1124905 0 989806 0 837477 523200 740381 0 0 0 0 905806 0 1164931 828347 0 0 309720 938712 328339 268266 312352 0 240227 336579 388901 0 548226 0 143965 338131 0 0 0 187648 383258 686658 407110 483460 0 147777 745770 382330 312452 368611 0 887615 0 0 491911 0 370564 340425 0 0 261117 410969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213655 0 0 0 0 598610 0 0 0 0 179080 0 0 0 0 0 0 0 0 0 0 942658 1571570 1268582 0 1112248 1398222 2300962 0 1099450 0 917933 1461048 1125926 0 0 1183858 1734293 487038 1059543 1329186 0 1561048 0 1650455 1326144 1219226 0 0 0 0 1428471 0 892693 1539285 0 0 939784 845293 0 0 0 0 0 0 153559 0 363806 0 0 0 0 0 0 0 0 0 746945 413148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEESAEEIQAA(Ala->Ser)LK MGYG000000249_01313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEESAEEIQAALK MGYG000000249_01313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1168136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1169990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEESAEEIQS(Methylamine)ALK MGYG000001315_01852 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,27I7U@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2294316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEESAEEIQSALK MGYG000001315_01852 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,27I7U@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 678299 1287593 455105 508012 465234 502950 946085 669696 961376 913340 766632 706307 318073 0 674661 0 0 669447 1329141 0 776034 0 446424 411354 594273 550856 0 597237 0 402103 526700 765061 0 685517 600105 545401 1048850 1248025 1527045 1136558 1551671 950836 1036543 1320430 1400321 983102 960113 830358 754155 1276353 1029116 0 613889 0 0 1365017 1456057 0 281166 0 1786443 1393446 1251782 1404650 0 1738824 0 1532997 1489640 1131686 1404139 1205412 1595843 1106367 1336753 488478 0 448825 501451 397742 0 322049 405573 0 0 0 362669 0 448620 0 0 0 0 0 0 0 254767 0 561789 347429 0 307923 0 0 0 0 328236 302933 384893 280365 0 0 400162 792112 970494 1872304 481151 910888 1277868 418065 486648 702179 1035142 1351797 1547494 1219893 487231 0 1388149 0 0 404474 676021 0 1487992 0 1207938 375434 511604 568866 0 633235 0 1022367 710944 2070650 503442 399103 557947 436300 2038807 563264 565924 1069933 576093 0 0 886682 667910 423784 494794 616695 469781 440983 856218 0 295414 0 0 463219 0 0 461143 0 473545 425387 306696 715030 0 647844 0 449916 313691 1493034 584711 670983 539481 412904 1249913 -AAEESAEEISA(Ala->Gln)ALK MGYG000000038_00850 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena|m__MGYG000000038 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,27URK@189330|Dorea 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 975133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1555136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEESAEELQAAVK MGYG000002492_02054 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 819079 377488 900359 138173 0 506069 493074 527803 782292 402685 0 0 0 512290 0 0 539972 444407 0 0 1327196 217204 454082 0 546536 1360818 0 0 689588 0 552630 0 597718 0 0 783948 0 0 2513352 914597 1192139 817405 0 835053 796251 798648 1255223 1293724 0 0 0 1332151 0 886507 1169829 792015 0 715308 1284429 670697 909787 0 754022 1372800 0 0 1224028 0 2646366 0 851746 0 0 2410371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838858 0 0 0 598286 0 0 0 0 0 0 0 0 500360 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877849 0 0 0 0 0 0 0 0 0 0 0 1422658 0 0 0 0 292982 0 0 0 0 0 0 0 0 0 0 -AAEESAEELSAAVK MGYG000001637_00515;MGYG000003215_00740;MGYG000000271_01162 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 501105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309083 0 0 0 0 0 0 0 0 0 0 674408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334052 0 0 0 0 0 0 0 0 0 0 510724 0 -AAEESAEELSAAVK(Propionamide) MGYG000001637_00515;MGYG000003215_00740;MGYG000000271_01162 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 1166330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1136498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396740 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEESGFNIR MGYG000004548_00792;MGYG000002517_02832 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 phosphate acetyltransferase 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHFR_1,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 254911 653004 0 334803 0 0 0 354521 0 0 0 0 0 0 395369 0 385396 0 464520 313264 0 0 0 0 0 0 373599 0 0 0 0 0 0 180207 232149 260571 232868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2667332 683408 218335 2408121 0 872244 1366379 2799854 2256971 1427687 926165 959092 885809 2939264 2388551 0 1655335 0 1795797 2160008 1031957 378307 0 0 3259114 2500217 2354966 0 0 1833096 932615 0 551603 1288354 2776601 2347093 2754762 725957 1205306 1257463 2045529 0 0 1589194 1582742 1045330 1230257 1953027 1378163 1437760 1173856 1732352 1772342 0 2401926 0 2570036 1346182 1209542 1170585 0 1439361 2179744 1529187 1818799 0 0 1180165 1317683 0 1973099 1570648 1205857 2265126 2406567 1753474 -AAEESIEDIK MGYG000004464_00237;MGYG000001346_02222;MGYG000004748_01432;MGYG000000236_00775 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,2FMJV@200643|Bacteroidia,4AMA1@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1720126 0 0 0 0 0 0 0 0 770919 0 0 0 0 0 0 0 0 0 0 1409667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEESIEEVK MGYG000001338_00984;MGYG000000213_00744;MGYG000000212_01066;MGYG000000200_00529;MGYG000004733_02036;MGYG000002966_03727;MGYG000000184_01385;MGYG000000252_02354;MGYG000000133_01126;MGYG000000171_01210;MGYG000002298_01448 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3XYK3@572511|Blautia 0.5454545454545454 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 1174182 1592137 1016086 662641 0 2231625 584595 955137 741793 947934 1570547 1343782 1198507 732444 924896 1329523 1120520 4162813 743101 1105643 1566001 2268848 1062591 1058071 1373921 857039 863757 1995813 2216697 1635415 917236 1620594 971263 989637 1190446 808608 770719 1109277 809229 2223307 566944 739934 695922 277023 578401 524445 549294 379305 613118 0 600058 317186 316968 0 122139 902193 658346 588197 725952 0 352202 711173 591346 527775 576615 719455 1132878 1058505 2597961 1039787 623867 1016916 512534 475687 410171 668337 927754 0 894325 566480 0 741077 363990 1124270 0 1283801 0 1022017 847833 601988 1101880 1021787 1215604 0 678030 859922 932008 0 328096 0 870873 999675 1179219 702008 918980 881782 1361515 1938594 1534747 1242132 1027282 0 1202992 1298764 0 2332143 666579 594545 1008736 676686 775139 0 429990 648270 742124 739714 675918 0 312583 699556 733559 0 0 654421 765892 444048 0 586449 172504 249060 0 0 2961610 1199788 1880573 1277510 632293 0 0 0 142192 928801 3430749 4337578 3854567 3869881 1174357 2875301 7654340 3834412 2697423 4331897 4215699 3547343 2682857 5021569 3608717 3367615 2844324 535606 3431316 1202510 4911460 3552456 1078873 3293249 3529217 4081258 4792887 1012680 4354925 896831 3515331 5012335 6093659 4339300 3822988 5684535 2064256 3279269 -AAEESKDEIANALK MGYG000002641_01976;MGYG000002619_00769;MGYG000000195_00044;MGYG000002040_00746;MGYG000002224_00374;MGYG000003899_00809;MGYG000002274_02915;MGYG000003291_00009;MGYG000002272_00283;MGYG000002545_02263;MGYG000000022_00593;MGYG000003937_01659;MGYG000002223_00729;MGYG000002610_00941;MGYG000001255_01690;MGYG000004700_01055;MGYG000000039_01295;MGYG000001300_02629 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 0.9444444444444444 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 1132838 1417357 1597531 1814293 891190 1214283 1353451 992890 1418885 0 1252353 1092745 1335876 1220444 961658 1441710 1354311 2314603 1500198 1257686 0 1104568 1941457 1425955 1200634 1263502 1093598 2014495 0 1031554 1279006 1067930 1503233 1952335 0 1279379 1556235 1645433 0 1485273 1753727 2423470 1240967 1723084 2419953 1072454 2827206 0 1084074 1389995 1020568 2826585 2956459 1138878 2334840 1597313 3170474 2059264 0 1159055 1406765 1178532 2627601 2239420 1911122 1171232 0 1521150 1322793 1358869 1690913 2035100 0 2015061 1963418 2113193 602890 187337 658257 642218 573572 580358 720683 345081 654214 0 830173 399175 713758 689452 346887 300880 300400 2829105 651422 0 0 0 2357184 546413 461577 637821 575280 2514112 0 535817 566108 632368 281129 518763 0 669739 715299 451178 1273949 1295050 1570021 1161043 1691538 1451883 1671959 1073164 1418887 0 1560044 1970522 1776311 1380171 1555470 1467020 1293431 1675131 1727927 1304656 0 1229130 1981218 1331876 1500774 1399144 1472271 1380345 0 1704713 1461688 1435894 1779450 2006417 0 1451827 1348484 1737019 0 0 0 0 0 226142 0 0 0 0 161676 0 0 0 0 0 0 1109969 0 0 0 0 1101515 229654 0 148726 0 1101774 0 0 0 0 0 0 0 0 0 0 -AAEESKDEITNALK MGYG000003921_01788 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEESMEELSSAVK MGYG000002517_01810 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 537773 0 0 794982 0 370776 230923 439257 348692 642505 0 551737 0 329164 603075 462281 517594 0 686106 441886 518218 0 0 0 595966 514376 652562 0 0 431692 0 0 0 450842 659376 752076 436942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277236 0 0 0 342118 341984 0 0 0 0 349604 533163 0 0 0 0 0 0 0 0 0 0 0 0 2976235 0 583844 2825447 0 966269 1479561 3797587 2951306 1557207 1412643 1335379 0 3243624 2973565 1177430 2248933 0 2699458 2712648 1774921 0 0 351017 3181185 2435444 2716456 0 0 2743343 0 0 662623 1795418 2735192 2124314 2766634 564572 2009161 0 2197312 0 0 1735570 1864007 1617068 2114182 2375103 1191212 1924839 0 2136013 3251226 1697974 2394273 0 2251010 1499193 2564447 1665931 0 1567419 2360633 1780791 2353247 0 0 1429581 0 0 2068301 2222786 1939032 2021963 2392755 1886646 -AAEESQEEISQALK MGYG000000233_02719;MGYG000000205_01980;MGYG000000255_01244 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,21YAS@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327991 0 0 0 0 346242 0 0 0 0 0 0 0 715785 0 0 647524 0 0 0 0 509513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816363 0 0 0 0 605279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369699 0 0 624825 0 0 0 0 472892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472647 0 0 0 0 552819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEESSEEISA(Ala->Gln)ALK MGYG000000164_02429 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1173172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEESSEEISQALK MGYG000000179_03344;MGYG000001622_01293;MGYG000002946_03659;MGYG000004087_01348;MGYG000001311_00488 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,21YAS@1506553|Lachnoclostridium 0.6 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 1009108 0 0 901653 0 243595 754320 0 787281 579163 0 0 0 0 645959 348962 0 0 392022 960549 869573 367401 0 376079 567424 1037053 700868 0 872751 690671 0 0 0 505116 687336 0 1069901 0 453721 0 121043 351597 0 0 461876 219887 299432 481730 0 0 239191 379161 337498 243924 0 0 414544 332540 0 0 0 212422 373666 219710 469765 0 319799 349058 0 0 149666 0 294548 166771 386840 0 854932 0 386757 794561 0 0 694988 370991 859239 534524 0 616047 525883 1061943 861913 564479 537462 0 708204 722455 862363 339764 0 0 302708 764484 1012097 0 921691 832149 542380 0 476643 656685 374802 970570 675047 434099 358818 0 0 308773 0 0 0 0 321833 349039 0 0 0 0 369134 358776 0 0 503411 197979 523243 0 0 0 0 0 349141 0 0 455897 0 0 423729 301505 428573 415945 267264 377345 1659772 0 841859 1191683 0 694904 831914 1028356 1640632 1297234 0 891823 607483 1246780 1442412 644213 1270970 0 1268265 1984270 1174980 1179073 0 1294492 868842 1729132 1277606 0 1769001 1155971 854801 0 803239 1099537 820178 1484646 1605929 892185 -AAEETKEAEPEAK MGYG000003683_01359 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG3937@1|root,COG3937@2|Bacteria,2GS3M@201174|Actinobacteria,4D1FE@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 S 1.0 granule-associated protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Phasin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 549731 0 0 0 0 470624 0 0 49584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140179 0 0 0 0 193563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEETKEAEPEAKAE MGYG000003683_01359 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG3937@1|root,COG3937@2|Bacteria,2GS3M@201174|Actinobacteria,4D1FE@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 S 1.0 granule-associated protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Phasin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1179603 0 1078136 1056792 0 0 0 0 0 0 0 0 0 1603081 0 0 0 0 0 0 0 1837539 0 0 0 0 0 0 0 0 1462788 0 0 0 0 663659 0 0 942245 0 768509 764452 0 0 0 0 0 0 2185153 0 0 1083771 0 0 0 0 0 791293 0 1154036 0 0 0 0 0 0 0 0 1164103 0 0 0 0 678957 0 0 647119 0 249943 380652 0 0 0 0 0 0 660577 0 0 748534 0 0 0 0 0 186890 0 166206 0 0 0 0 0 0 0 0 482084 0 0 0 0 345876 0 0 0 0 0 0 0 0 0 0 0 0 687323 0 0 0 0 0 0 0 0 0 0 766337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEEVGASDLTK MGYG000000223_01552 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,3VQHN@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 278698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 202584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1564656 0 0 0 0 0 0 0 0 3882949 0 0 0 0 0 0 0 0 0 486057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1979039 0 0 0 0 0 0 0 0 4268187 0 2331038 0 0 0 0 0 0 0 3486085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635420 0 0 0 0 0 0 0 0 380995 0 6195498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEEYPMNLGFLGK MGYG000002835_01962;MGYG000000200_02255;MGYG000000133_02315 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,24D62@186801|Clostridia,3WGSE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family 1.0 ureC 1.0 - 1.0 3.5.1.5 1.0 ko:K01428 1.0 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 1.0 - 1.0 R00131 1.0 RC02798,RC02806 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_1,Urease_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 urease. - - 2 H(+) + H2O + urea = CO2 + 2 NH4(+). 1.0 1.0 1.0 1.0 Atrazine degradation;Purine metabolism;Arginine biosynthesis;Metabolic pathways;Epithelial cell signaling in Helicobacter pylori infection;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2036807 0 0 0 0 753576 0 0 0 0 1604848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032494 0 0 0 0 1782641 0 0 0 0 1399955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354442 0 0 0 0 0 0 0 0 0 0 -AAEFADVLK MGYG000001302.1_00924 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG1027@1|root,COG1027@2|Bacteria,4P1PR@976|Bacteroidetes,2FNWI@200643|Bacteroidia,22U5D@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Aspartate ammonia-lyase 1.0 aspA 1.0 - 1.0 4.3.1.1 1.0 ko:K01744 1.0 ko00250,ko01100,map00250,map01100 1.0 - 1.0 R00490 1.0 RC00316,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FumaraseC_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate ammonia-lyase. fumaric aminase. - L-aspartate = fumarate + NH4(+). 1.0 1.0 1.0 1.0 Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400307 0 0 0 0 280027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422404 0 0 0 0 348905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1633896 0 0 0 0 1184300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEFDYAGTQAC(Carbamidomethyl)R MGYG000002517_00535 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Carbamoyl-phosphate synthetase ammonia chain 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 316618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 557196 0 0 0 0 0 0 613993 0 0 0 0 0 943797 0 0 0 0 0 724236 0 0 0 0 0 746078 0 0 0 761822 0 0 0 0 0 0 517420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEFLEEPIER MGYG000000084_01972;MGYG000000724_01019 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 815650 0 0 0 0 571092 0 0 0 0 2421619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 886963 0 0 0 0 584090 0 0 0 0 595585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1075045 0 0 0 0 922939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 790198 0 0 0 0 1038701 0 0 0 0 845383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1372548 0 0 0 0 2029155 0 0 0 0 1785458 0 0 0 0 0 0 0 0 0 0 -AAEGAAAAAATEASAC(Carbamidomethyl)AN(Deamidated)C(Carbamidomethyl)AEK MGYG000000003_00044 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGAAAAAATEASAC(Carbamidomethyl)ANC(Carbamidomethyl)AEK MGYG000000003_00044 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 1418046 1438025 0 1407713 1314130 1526458 893170 0 1511493 1741333 716593 2527430 0 1451193 2249784 0 2236875 0 1894042 1797021 1802108 1212332 0 2260617 0 2102972 2146866 0 0 2351259 0 0 0 0 1285875 1819976 1348932 0 563848 382781 0 820456 930135 592283 478577 0 601745 900012 471301 1066781 0 716216 921560 0 451429 0 401084 654914 594864 363353 0 529732 0 690363 565255 0 0 699642 0 0 0 0 358543 321840 802550 0 1362692 666011 0 688606 1021336 437474 636554 0 907588 363481 646327 1040528 0 827960 843140 0 313127 0 710889 1076277 1289465 591803 0 504195 0 1010108 910346 0 0 1323020 0 0 0 0 938142 1181683 896888 0 290632 0 0 375543 662118 175842 0 0 502712 390828 154238 786494 0 388821 637924 0 301945 0 720933 357478 443948 0 0 0 0 383156 323665 0 0 441784 0 0 0 0 0 385847 567228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGAATQSVADQEEIK MGYG000001346_02907 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 378413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGAATQSVADQEEIKK MGYG000001346_02907 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 318610 395977 560018 259503 431944 0 0 0 2740045 841787 500039 480421 0 910308 388710 446816 0 0 0 355025 534296 420548 0 0 0 517092 0 0 0 582785 411482 0 0 0 0 354627 0 0 913600 739822 0 670361 436844 0 0 0 845603 2024044 570394 655607 0 956113 561312 310519 0 0 0 716757 280661 538591 0 0 0 394639 0 0 0 1120332 642180 0 0 0 0 587914 0 0 844833 746212 1462125 1030103 995972 0 0 0 4442332 849720 877486 840808 0 959263 811186 2032282 0 0 0 681524 1686629 1137836 0 0 0 1579769 0 0 0 700131 614331 0 0 0 0 1072064 0 0 653621 508728 737358 638850 584112 0 0 0 1217592 1583350 705492 484919 0 865278 433132 235180 0 0 0 409825 409700 273304 0 0 0 309223 0 0 0 645342 572129 0 0 0 0 661190 0 0 722142 781487 1040785 756179 715996 0 0 0 5868283 1141971 1384340 199687 0 1219700 733106 1415807 0 0 0 712501 1195261 633762 0 0 0 1268858 0 0 0 648456 327885 0 0 0 0 654083 -AAEGAATQSVAN(Deamidated)QEEIKK MGYG000001370_00660 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fluxus|m__MGYG000001370 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGAGHSLYTSTDYM(Oxidation)LDGYDNAEPADPVQHR MGYG000000243_02695 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0614@1|root,COG0614@2|Bacteria,4NEF0@976|Bacteroidetes,2FNDC@200643|Bacteroidia,4AMJ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 559603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642483 0 0 0 0 551371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290845 -AAEGAGHSLYTSTDYMLDGYDN(Deamidated)AEPADPVQHR MGYG000000243_02695 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0614@1|root,COG0614@2|Bacteria,4NEF0@976|Bacteroidetes,2FNDC@200643|Bacteroidia,4AMJ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 1108663 0 0 0 0 0 0 0 0 0 0 1671700 0 0 0 0 0 1695819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 931156 0 0 0 474612 0 0 0 0 0 0 0 0 0 0 621037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGAGHSLYTSTDYMLDGYDNAEPADPVQHR MGYG000000243_02695 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0614@1|root,COG0614@2|Bacteria,4NEF0@976|Bacteroidetes,2FNDC@200643|Bacteroidia,4AMJ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2668083 3004896 6957129 4438162 2875867 2514392 3885120 3512998 3368466 1561529 2557790 2753027 1313191 2742586 1950907 1313835 2285650 994011 2275482 2004000 2228975 2335955 1823013 3320984 2520942 2814195 3108780 2546984 2513959 3741715 7335511 2967928 5704183 3536910 3133258 3335033 2656715 5702901 932449 776044 1057041 1262393 1670501 1376303 1153127 1705457 864295 1530360 1610734 1086669 1751383 1666214 1504220 2228824 1645715 536304 1413207 1221852 1425259 1499575 701508 1381737 1216638 1563701 1663208 271874 1075599 1328964 973742 1712183 957061 1024239 1356261 1063794 1264583 1118621 888937 486713 871697 706650 1327856 1228380 1375607 558601 1020355 944959 1025640 1099517 897620 1083192 887660 948392 615461 1357522 1170758 620987 768878 201632 803858 1311300 965060 1243943 523275 633102 620539 917201 1233796 805863 989290 252184 1111917 1296696 1543699 1145629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGAIGIAEK MGYG000000251_02115;MGYG000000142_02731;MGYG000001615_01983;MGYG000000233_02118;MGYG000001338_01296;MGYG000002528_00119;MGYG000000205_02543;MGYG000001707_00757;MGYG000000262_01832;MGYG000003425_04615;MGYG000002517_01686;MGYG000004733_02764;MGYG000002492_01963;MGYG000000212_00326 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.21428571428571427 186801|Clostridia 0.8571428571428571 S 0.8571428571428571 Psort location Cytoplasmic, score 8.87 0.35714285714285715 - 0.8571428571428571 - 1.0 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 1.0 - 1.0 - 1.0 GGGtGRT 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 978382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3943931 0 0 0 0 0 0 4601626 0 0 0 0 0 0 0 5004474 0 0 4876314 0 0 0 2888106 0 0 0 6069781 4713004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGAIGIAR MGYG000000036_01924;MGYG000003937_01695 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5397697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGDDALMEK MGYG000004158_01417 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister invisus|m__MGYG000004158 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4H2Y7@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 369465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGEDEQKAVEHLVK MGYG000002494_03969 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1925@1|root,COG1925@2|Bacteria,1N0CV@1224|Proteobacteria,1S9R2@1236|Gammaproteobacteria,3X2IH@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 PTS HPr component phosphorylation site 1.0 ptsH 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005981,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008047,GO:0008150,GO:0008152,GO:0008643,GO:0008965,GO:0008982,GO:0009401,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015144,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0019197,GO:0019222,GO:0022804,GO:0022857,GO:0030234,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032881,GO:0032991,GO:0034219,GO:0043085,GO:0043467,GO:0043470,GO:0043471,GO:0044093,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045819,GO:0045913,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051179,GO:0051234,GO:0055085,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0065009,GO:0070873,GO:0070875,GO:0071702,GO:0080090,GO:0098772 1.0 - 1.0 ko:K02784 1.0 ko02060,map02060 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02000 1.0 8.A.8.1.1 1.0 - 1.0 e_coli_core.b2415,iAF1260.b2415,iB21_1397.B21_02276,iBWG_1329.BWG_2177,iE2348C_1286.E2348C_2601,iEC042_1314.EC042_2624,iEC55989_1330.EC55989_2705,iECABU_c1320.ECABU_c27360,iECBD_1354.ECBD_1266,iECB_1328.ECB_02315,iECDH10B_1368.ECDH10B_2580,iECDH1ME8569_1439.ECDH1ME8569_2349,iECDH1ME8569_1439.EcDH1_1246,iECD_1391.ECD_02315,iECED1_1282.ECED1_2859,iECH74115_1262.ECH74115_3646,iECIAI1_1343.ECIAI1_2473,iECIAI39_1322.ECIAI39_2561,iECNA114_1301.ECNA114_2492,iECO103_1326.ECO103_2934,iECO111_1330.ECO111_3145,iECO26_1355.ECO26_3468,iECOK1_1307.ECOK1_2732,iECP_1309.ECP_2439,iECS88_1305.ECS88_2605,iECSE_1348.ECSE_2706,iECSF_1327.ECSF_2279,iECSP_1301.ECSP_3363,iECUMN_1333.ECUMN_2737,iECW_1372.ECW_m2644,iECs_1301.ECs3287,iEKO11_1354.EKO11_1313,iETEC_1333.ETEC_2528,iEcDH1_1363.EcDH1_1246,iEcE24377_1341.EcE24377A_2702,iEcHS_1320.EcHS_A2550,iEcSMS35_1347.EcSMS35_2570,iEcolC_1368.EcolC_1263,iG2583_1286.G2583_2947,iJO1366.b2415,iJR904.b2415,iLF82_1304.LF82_1769,iNRG857_1313.NRG857_12110,iPC815.YPO2993,iSBO_1134.SBO_2439,iSDY_1059.SDY_2612,iSFV_1184.SFV_2467,iSF_1195.SF2470,iSFxv_1172.SFxv_2719,iSSON_1240.SSON_2504,iS_1188.S2616,iSbBS512_1146.SbBS512_E2765,iUMN146_1321.UM146_04545,iUMNK88_1353.UMNK88_3017,iUTI89_1310.UTI89_C2749,iWFL_1372.ECW_m2644,iY75_1357.Y75_RS12655,iZ_1308.Z3681,ic_1306.c2950 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 68347 0 0 367406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1871337 1667442 0 1704266 3048703 0 0 0 1596552 0 0 0 0 0 0 0 0 1260948 0 0 3569903 0 2751078 0 0 0 0 0 0 0 1834065 1577616 0 0 0 0 2192008 0 451028 0 0 0 819493 0 0 0 0 0 0 0 0 0 0 0 0 377188 0 0 654531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGGDILFVGTK MGYG000000022_01263;MGYG000001300_00246;MGYG000002223_00595;MGYG000000039_00227;MGYG000002274_00630;MGYG000002651_00048 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 995446 1034726 995268 0 500832 737528 1045934 0 1380483 1035922 1296304 987892 941523 0 0 826858 999354 0 1045895 1050597 0 884209 0 1271810 946383 1332717 1361845 0 0 1093855 0 0 912902 1329492 0 0 1038659 976981 989566 715108 1053428 0 899577 801489 1236451 0 895419 0 776094 918023 1408950 0 0 670303 1283033 0 1132026 867987 0 634568 0 623080 1058262 1003621 732579 0 0 1019420 0 0 781410 1044583 0 0 682618 815957 597902 412530 627009 0 688319 584091 606049 0 633571 619998 652211 747534 621273 0 0 481006 686608 0 595789 480829 0 533252 0 746207 569340 679390 319452 0 0 637310 0 0 469752 537927 0 0 608834 576170 651140 694896 965727 0 1375668 1049889 873290 0 1267409 713059 2027150 1261778 1228164 0 0 1606801 1469753 0 1235247 834726 0 1190292 0 1127843 752639 783924 757318 0 0 847648 0 0 783659 976602 0 0 672991 537047 382987 257889 677831 0 192185 431165 304527 0 320602 0 357801 383089 193363 0 0 507724 0 0 502895 289117 0 734127 0 367436 285395 258099 460339 0 0 239450 0 0 588198 467283 0 0 422824 553579 -AAEGGDILFVGTKK MGYG000002272_01435;MGYG000001300_00246;MGYG000000039_00227;MGYG000002274_00630;MGYG000002545_00160 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 757547 702584 999845 1153984 0 741149 455733 0 700478 0 0 0 0 0 0 0 0 452780 1053091 0 0 695234 697386 855508 0 816878 0 801093 0 0 0 0 787637 999492 0 0 307120 1013171 556919 311314 922304 686367 0 631348 876130 0 926148 0 0 0 0 0 0 0 0 274913 736210 0 0 362375 149277 323860 0 340975 0 438804 0 0 0 0 553470 410653 0 0 474738 615698 286259 325037 163993 268327 0 531609 233498 0 324010 0 0 0 0 0 0 0 0 343971 403615 0 0 235110 256266 522172 0 311417 0 324597 0 0 0 0 238770 316257 0 0 169652 290083 582881 563016 1136800 521504 0 879824 726508 0 659883 0 0 0 0 0 0 0 0 271979 991352 0 0 775542 597723 933729 0 808594 0 286697 0 0 0 0 1238126 1205126 0 0 728198 244086 245993 218436 490545 167178 0 447235 124961 0 484382 0 0 0 0 0 0 0 0 204212 417868 0 0 497870 380348 502000 0 506850 0 618924 0 0 0 0 326363 480806 0 0 549442 171442 -AAEGGFDISGAQIVDPEKSDR MGYG000000142_02451 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,3XZ2B@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1008902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGGFDISGATIVDPETSDR MGYG000000133_02974 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,3XZ2B@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 765449 0 0 0 0 0 0 0 0 0 0 579354 0 0 0 745121 0 0 0 0 530391 0 0 0 0 -AAEGIAPK MGYG000002506_04253 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,3XP43@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also catalyzes the hydration of 2-methyl-cis- aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnB functions as a RNA-binding regulatory protein. During oxidative stress inactive AcnB apo-enzyme without iron sulfur clusters binds the acnB mRNA 3' UTRs (untranslated regions), stabilizes acnB mRNA and increases AcnB synthesis, thus mediating a post-transcriptional positive autoregulatory switch. AcnB also decreases the stability of the sodA transcript 1.0 acnB 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006417,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019222,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032787,GO:0034248,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046395,GO:0046459,GO:0046487,GO:0047456,GO:0048037,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0072329,GO:0072350,GO:0080090,GO:0097159,GO:1901363,GO:1901575,GO:2000112 1.0 4.2.1.3,4.2.1.99 1.0 ko:K01682 1.0 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 1.0 M00009,M00010,M00012,M00173 1.0 R01324,R01325,R01900,R04425 1.0 RC00497,RC00498,RC00618,RC01153 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECIAI1_1343.ECIAI1_0116,iPC815.YPO3415 1.0 Aconitase,Aconitase_2_N,Aconitase_B_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aconitate hydratase. | 2-methylisocitrate dehydratase. citrate hydro-lyase. | (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase. Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate.-!-The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate.-!-cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate.-!-Formerly EC 4.2.1.4. | The enzyme from the fungus Yarrowia lipolytica does not act on isocitrate. citrate = D-threo-isocitrate. | (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Citrate cycle (TCA cycle);Glyoxylate and dicarboxylate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments;Propanoate metabolism;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3910203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGILTVR MGYG000001423_03022;MGYG000001367_01857;MGYG000004735_00207;MGYG000004087_01282;MGYG000004642_01131 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,36DMF@31979|Clostridiaceae 0.4 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1994659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGLC(Menadione-HQ)KTLVSEDGKK MGYG000001338_02308 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1011900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877650 0 0 0 0 527274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395550 0 0 0 0 381408 -AAEGLHMRPAGVIAR MGYG000002492_00320 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,25XE8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 PTS HPr component phosphorylation site 1.0 ptsH 1.0 - 1.0 - 1.0 ko:K11189 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 83074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 387179 412709 889817 0 0 0 0 0 2525087 0 2164686 0 0 0 0 1650530 0 0 0 0 1134618 0 0 0 0 1135624 0 0 0 0 283891 0 0 0 0 572884 0 0 615952 0 319185 0 0 0 0 0 525612 0 258301 0 0 0 0 801764 0 0 0 0 1086564 0 0 0 0 1268890 0 0 0 0 726311 0 0 0 0 914828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGSVHSDNFR MGYG000002492_00394 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 324591 0 335208 0 0 0 0 0 391264 0 449842 0 0 276793 0 433509 0 0 0 0 219790 0 0 0 0 295420 0 0 0 0 310340 0 0 0 0 175736 0 0 1082493 0 1453665 0 0 0 0 0 1266976 0 1372711 0 0 1201098 0 4461658 0 0 0 0 1967120 0 0 0 0 3154505 0 0 0 0 940094 0 0 0 0 1240733 0 0 6056962 0 1883231 0 0 0 0 0 2187377 0 3032477 0 0 3034452 0 1215090 0 0 0 0 1823503 0 0 0 0 2267672 0 0 0 0 5583749 0 0 0 0 6956769 0 0 641055 0 290756 0 0 0 0 0 872581 0 84554 0 0 390502 0 1173152 0 0 0 0 588394 0 0 0 0 1021209 0 0 0 0 570127 0 0 0 0 726862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGSVHSDNFRR MGYG000002492_00394 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177452 0 0 0 0 0 0 0 1592942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994382 0 0 0 0 1415312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGTEFAALDPHLEGPTALAVSKDDATAPAR MGYG000000242_00770 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,269HE@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489346 0 0 0 0 760056 0 0 0 0 1044601 0 0 0 0 0 0 0 0 0 0 -AAEGTEFAALEPQLEGPTALAVSKEDATAPAR MGYG000000179_05049;MGYG000000198_05827 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,269HE@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 685695 0 0 278879 0 0 0 0 279502 0 0 0 0 493804 0 0 0 0 0 0 0 216481 0 0 482633 531932 328410 0 376801 0 0 0 0 0 0 382899 265166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 214636 0 0 0 0 0 0 0 0 0 0 0 0 337452 0 248694 0 0 0 0 0 0 0 178182 0 459779 0 200243 288187 0 0 0 0 488092 0 0 0 0 540410 0 0 0 0 0 0 0 282103 0 0 0 0 323797 0 623389 0 0 0 243657 0 0 206778 0 252306 0 0 0 223627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 849679 0 628478 986673 0 320524 0 0 820955 0 0 0 0 1619846 0 0 0 0 0 0 0 424331 0 638052 839662 1133950 1208263 0 1261913 0 0 0 969200 0 0 1251935 883104 498677 -AAEGTGIEIAPLK MGYG000002485_02279;MGYG000002574_00479 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG4656@1|root,COG4656@2|Bacteria,3791P@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4,Fer4_10,Fer4_17,Fer4_4,Fer4_7,Fer4_9,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 737531 479876 1575850 0 702557 2563509 0 0 0 2072889 1605092 0 1511699 0 0 2102634 1168045 0 1063490 0 0 2363038 0 1963625 0 814730 844599 0 0 752275 1649835 762000 1645807 0 0 0 683520 1436534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354383 0 229594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEGWAR MGYG000002494_02221 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,3XNJZ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Glycyl-tRNA synthetase beta subunit 1.0 glyS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.14 1.0 ko:K01879 1.0 ko00970,map00970 1.0 M00360 1.0 R03654 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 1.0 DALR_1,tRNA_synt_2f 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine--tRNA ligase. glycyl-tRNA synthetase. - ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 97997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228410 0 0 0 0 97363 0 0 931967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 952921 0 0 0 0 805168 0 0 379633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156552 0 0 0 0 295267 0 0 376361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347437 0 0 0 0 124627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91300 0 0 0 0 0 -AAEHLAHTGLLK MGYG000002994_01435 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Megasphaeraceae|g__Megasphaera|s__Megasphaera sp002319965|m__MGYG000002994 1.0 COG4670@1|root,COG4670@2|Bacteria,1TP5H@1239|Firmicutes,4H37Q@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Belongs to the 3-oxoacid CoA-transferase family 1.0 - 1.0 - 1.0 2.8.3.1 1.0 ko:K01026 1.0 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 1.0 - 1.0 R00928,R01449,R05508 1.0 RC00012,RC00014,RC00137 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 propionate CoA-transferase. - Butanoate and lactate can also act as acceptors. acetyl-CoA + propanoate = acetate + propanoyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways;Styrene degradation;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1522061 0 0 0 0 0 0 0 0 0 0 0 -AAEHPSEQVGK MGYG000000245_00071;MGYG000000325_00446;MGYG000000271_00298;MGYG000004271_02052 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 1.0 186801|Clostridia 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 1206303 860887 659242 1919503 992508 1034432 1665662 725414 1608194 1493497 2571629 2284661 1183858 924544 2140640 1152058 1505034 2006059 996168 1168687 1482561 1259313 2167886 1128811 2011847 1375731 1564148 2493211 1120810 1996788 640514 870934 547434 1327624 696163 1375940 1155217 568096 87292 32572 0 52324 56819 0 0 0 0 0 71781 66163 0 55794 0 0 0 506492 0 0 169672 38337 855349 0 0 0 63702 852922 29023 39681 52038 59774 0 0 45642 0 74215 0 514278 358034 0 536935 185308 200242 402087 531822 676336 272933 397465 1004454 745293 731990 725923 661541 637215 199293 629673 675951 526366 161390 97374 202841 732316 884996 846297 217486 460406 730994 143729 143427 205877 445632 277995 697830 947496 143509 96994 0 59021 80534 100968 42406 67511 57055 0 54652 135511 414048 0 75663 0 86575 0 140170 0 139340 0 0 0 0 67958 93237 65879 192982 0 97842 0 138413 0 0 75497 0 0 128506 354431 172328 275469 0 49091 274255 493502 185144 458339 401608 226056 1058326 342304 358569 480943 216503 495458 1547355 393362 303416 79913 364396 3023852 314535 355055 538195 317533 828104 119026 403807 78468 125246 241690 337799 281146 780550 427849 229548 -AAEHPSEQVGKEIR MGYG000000245_00071;MGYG000000271_00298;MGYG000004271_02052 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 1.0 186801|Clostridia 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEHPSEVVGEEIR MGYG000004735_00452;MGYG000001315_02512 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 0.5 186801|Clostridia 1.0 EH 0.5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 0.5 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 520643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254756 0 0 0 0 272011 0 0 238043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 301608 0 0 0 0 332128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101553 0 0 0 0 0 0 0 218094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183413 0 0 0 0 363637 0 0 298801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194182 0 0 0 0 393632 -AAEHPSEVVGEEIRK MGYG000001315_02512 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,36DKA@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS10005,iHN637.CLJU_RS10010 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEHVVGVAK MGYG000000201_02350;MGYG000000223_00229;MGYG000001315_00988;MGYG000002528_00902 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 0.25 186801|Clostridia 1.0 C 1.0 Rubrerythrin 0.75 rbr3A 1.0 - 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 182397 199198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053794 0 0 0 0 626681 0 0 0 0 988803 0 0 124284 0 338546 0 0 0 0 434283 0 0 73952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 57120 0 0 0 0 61017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49732 0 0 0 0 0 0 0 0 0 0 0 0 71191 0 0 0 0 0 0 0 0 1149894 509014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733103 0 0 0 0 268657 0 0 0 0 2090998 0 0 1117184 0 651564 0 0 0 0 1014505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEI(Xle->Val)PEAIRK MGYG000000136_02061;MGYG000002670_00403;MGYG000001315_01353;MGYG000002234_01458;MGYG000004733_00985;MGYG000003891_01006;MGYG000000252_01802;MGYG000000280_01284;MGYG000000031_02249;MGYG000000142_02050;MGYG000002492_00392;MGYG000000135_01188;MGYG000000690_01576;MGYG000000028_01605;MGYG000004689_01598;MGYG000002517_02856;MGYG000000002_00865;MGYG000002966_02558;MGYG000001186_01095;MGYG000000213_00197;MGYG000004296_00406;MGYG000000806_01299;MGYG000002278_02309;MGYG000000050_01189;MGYG000002298_00345;MGYG000000193_02113;MGYG000000201_02098;MGYG000000301_00177;MGYG000004879_01580;MGYG000001338_02790;MGYG000002528_01856;MGYG000000164_02747;MGYG000001689_02303;MGYG000000562_01931;MGYG000000133_00062;MGYG000001645_00457;MGYG000000212_03064;MGYG000000184_01189;MGYG000003694_02445;MGYG000000216_02346;MGYG000000251_01814;MGYG000001637_00014;MGYG000000187_01741 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.46511627906976744 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1653331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEIAKNTM(Oxidation)AER MGYG000000271_00931 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins 1.0 iscS 1.0 - 1.0 2.8.1.7 1.0 ko:K04487 1.0 ko00730,ko01100,ko04122,map00730,map01100,map04122 1.0 - 1.0 R07460,R11528,R11529 1.0 RC01789,RC02313 1.0 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 cysteine desulfurase. cysteine desulfurylase. The sulfur from free L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors.-!-The enzyme is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin).-!-In Azotobacter vinelandii, this sulfur provides the inorganic sulfide required for nitrogenous metallocluster formation. [sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine. 1.0 1.0 1.0 1.0 Thiamine metabolism;Metabolic pathways;Sulfur relay system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEIAKNTMAER MGYG000000271_00931 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins 1.0 iscS 1.0 - 1.0 2.8.1.7 1.0 ko:K04487 1.0 ko00730,ko01100,ko04122,map00730,map01100,map04122 1.0 - 1.0 R07460,R11528,R11529 1.0 RC01789,RC02313 1.0 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 cysteine desulfurase. cysteine desulfurylase. The sulfur from free L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors.-!-The enzyme is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin).-!-In Azotobacter vinelandii, this sulfur provides the inorganic sulfide required for nitrogenous metallocluster formation. [sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine. 1.0 1.0 1.0 1.0 Thiamine metabolism;Metabolic pathways;Sulfur relay system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEIATANMK MGYG000002517_00912 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins 1.0 iscS 1.0 - 1.0 2.8.1.7 1.0 ko:K04487 1.0 ko00730,ko01100,ko04122,map00730,map01100,map04122 1.0 - 1.0 R07460,R11528,R11529 1.0 RC01789,RC02313 1.0 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 cysteine desulfurase. cysteine desulfurylase. The sulfur from free L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors.-!-The enzyme is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin).-!-In Azotobacter vinelandii, this sulfur provides the inorganic sulfide required for nitrogenous metallocluster formation. [sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine. 1.0 1.0 1.0 1.0 Thiamine metabolism;Metabolic pathways;Sulfur relay system 1.0 none 1.0 809019 0 426703 635154 0 554316 0 0 0 0 0 0 0 507993 0 509466 525863 0 0 0 657792 604797 0 534759 0 594910 0 0 0 0 0 0 718892 0 0 0 480073 372896 217325 0 348500 0 0 0 0 0 0 0 0 0 0 0 0 320353 0 0 0 0 0 152473 0 0 0 314092 0 0 0 0 0 0 0 0 0 0 270911 0 0 0 305143 0 0 307147 0 0 0 0 0 0 0 0 0 267754 175325 0 0 0 0 543009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2721052 0 0 2776166 0 3674433 0 0 0 0 0 0 0 2705961 0 3275283 2611056 0 0 0 2730066 2449569 0 731092 0 2652198 0 0 0 0 0 0 1937493 0 0 0 3130239 3818825 1076995 0 2917502 0 0 2834310 0 0 0 0 0 0 0 2247979 0 1576125 2156247 0 0 0 1994071 2146956 0 2180304 0 1663370 0 0 0 0 0 0 2396133 0 0 0 1623382 2245944 -AAEIDEEERFPMETVEK MGYG000002926_00639;MGYG000002720_01506 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2N683@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Psort location Cytoplasmic, score 9.97 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 585369 0 0 0 0 0 0 0 0 1099917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 819873 0 0 0 0 0 0 0 0 0 0 643309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352991 0 0 0 0 0 0 0 0 382508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179340 0 0 0 0 0 0 0 0 0 0 458886 0 408610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 592245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEIGKELEAELNQK MGYG000001313_00488 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,2FMB9@200643|Bacteroidia,4AM6Q@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Oxidoreductase, short chain dehydrogenase reductase family protein 1.0 uxuB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1128497 0 0 0 0 1043655 0 0 0 0 777982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 97819 0 0 0 0 0 0 0 0 0 0 -AAEIIDAFNEQGGAF(Oxidation[F](Phe->Tyr)K MGYG000000243_01974 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443011 0 0 0 0 0 0 0 0 0 0 0 0 961141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4158155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1594134 0 0 0 0 669900 0 0 0 0 564362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEIIDAFNEQGGAFK MGYG000000243_01974 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724408 0 1107859 0 0 0 0 0 0 0 0 0 0 0 0 717206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 919583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEIIDAFNEQGGAYK MGYG000002478_00802 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1084914 0 0 0 0 937345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2210699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEIIR MGYG000002033_00724;MGYG000002438_02893;MGYG000000243_00603;MGYG000004464_00649 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,22W81@171551|Porphyromonadaceae 0.75 976|Bacteroidetes 1.0 C 1.0 Electron transfer flavoprotein 0.75 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2399333 0 0 0 -AAEIIREGLYR MGYG000004797_03900;MGYG000001787_00188;MGYG000000243_00603 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,4AN6T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG2086 Electron transfer flavoprotein beta subunit 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEILDAFNEQGGAYK MGYG000002478_00802;MGYG000003367_01247 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEILDAYNEQGGAFK MGYG000003693_00190;MGYG000001306_02657;MGYG000001364_02757 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3590379 0 0 0 0 4395911 0 0 0 0 3761221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEILDAYNEQGGAFKR MGYG000003693_00190;MGYG000001306_02657 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2258169 0 0 0 0 2834471 0 0 0 0 2347681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239989 0 0 0 0 0 0 0 0 0 271066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316437 0 0 0 0 912660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEILDK MGYG000000650_00860;MGYG000000909_00761;MGYG000000198_01719;MGYG000001619_01872 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,21YT8@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) 1.0 purE 1.0 - 1.0 5.4.99.18 1.0 ko:K01588 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R07405 1.0 RC01947 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 5-(carboxyamino)imidazole ribonucleotide mutase. N(5)-carboxyaminoimidazole ribonucleotide mutase. In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates.-!-In the absence of EC 6.3.2.6, the reaction is reversible.-!-The substrate is readily converted into 5-amino-1-(5-phospho-D- ribosyl)imidazole by non-enzymic decarboxylation. 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1- (5-phospho-D-ribosyl)imidazole-4-carboxylate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 632340 0 0 0 0 0 0 0 0 0 0 0 0 518389 653925 0 0 0 0 0 0 0 0 0 0 508327 0 0 0 0 0 0 0 0 0 0 793627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 497095 304415 0 0 0 0 0 0 0 0 0 0 292015 0 0 0 0 0 0 0 0 0 0 322058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1969015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1427739 0 0 0 0 0 0 0 0 0 0 0 0 1003437 577671 0 0 0 0 0 0 0 0 0 0 1273794 0 0 0 0 0 0 0 0 0 0 816116 0 -AAEILDLTEYLDRKPK MGYG000003683_01833;MGYG000002395_01772;MGYG000001292_02614;MGYG000002469_02049 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CYU6@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 E 1.0 Belongs to the ABC transporter superfamily 1.0 ugpC 1.0 - 1.0 - 1.0 ko:K10112 1.0 ko02010,map02010 1.0 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1 1.0 - 1.0 - 1.0 ABC_tran,TOBE,TOBE_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 53276 242817 668010 0 495850 388954 87375 628810 0 305761 767861 2973644 859581 0 156273 398926 321284 0 214967 361537 342347 286060 0 81372 376249 282341 217504 0 601784 517608 230609 400986 353001 294481 324674 238543 268371 461918 317387 697919 429156 0 818307 630261 575426 439115 0 642235 1422296 367293 2109954 0 686521 409989 303945 0 400645 447644 372483 532285 0 995062 566412 539902 503842 0 934633 581638 888195 717074 302882 630380 602084 528740 436458 541071 631043 707351 378887 0 364071 219184 267594 703701 0 691198 474629 769236 484184 0 656521 672802 573612 0 443520 654054 450004 601447 0 256126 534770 147666 615742 0 368853 649754 179806 806512 864875 799030 975343 306336 502133 465948 351424 83690 315674 0 478246 552270 384496 131865 0 346302 747335 283842 54078 0 152383 267086 198646 0 64644 135630 226779 827011 0 707285 305739 157690 194068 0 425069 58804 367899 276766 150666 28441 386576 62984 240508 163749 0 0 59502 0 0 0 68757 65027 0 0 0 69486 0 0 0 0 86165 0 160696 79572 92369 0 0 0 0 0 191820 0 259678 466525 31596 0 0 0 0 67313 73285 0 -AAEILNTVNK MGYG000000196_00042 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG3538@1|root,COG3538@2|Bacteria,4NGY6@976|Bacteroidetes,2FM8H@200643|Bacteroidia,4AMK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Conserved protein 1.0 - 1.0 - 1.0 - 1.0 ko:K09704 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_125 1.0 3.2.1.- 1.0 GH125 1.0 GH125 1.0 GH125 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEILR MGYG000002438_02893;MGYG000004797_03900;MGYG000000179_00118;MGYG000004105_01672;MGYG000000243_00603;MGYG000000354_00400;MGYG000004711_01572;MGYG000002033_00724;MGYG000000273_00875;MGYG000002445_02556;MGYG000000262_01672;MGYG000000650_01893;MGYG000001531_01601;MGYG000000278_01741;MGYG000004479_00382;MGYG000003504_00715;MGYG000001608_02430;MGYG000001787_00188;MGYG000000233_00376;MGYG000001364_02529;MGYG000004464_00649;MGYG000002218_00405;MGYG000000133_02950;MGYG000001300_00650;MGYG000004468_01621;MGYG000001954_00593;MGYG000001750_01698;MGYG000000170_02403;MGYG000001789_02010;MGYG000004735_00212;MGYG000001783_00812;MGYG000001367_01866;MGYG000004087_01272;MGYG000000043_03473;MGYG000000174_04854;MGYG000001429_00437;MGYG000001619_00903;MGYG000001655_00932;MGYG000000355_01943;MGYG000001489_04896;MGYG000002025_02339;MGYG000000301_01699 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,22W81@171551|Porphyromonadaceae 0.2619047619047619 976|Bacteroidetes 0.5952380952380952 C 0.5952380952380952 Electron transfer flavoprotein 0.3333333333333333 etfB 0.5952380952380952 - 1.0 - 0.9285714285714286 ko:K03521 0.5952380952380952 - 0.9285714285714286 - 0.9523809523809523 - 0.9285714285714286 - 0.9285714285714286 ko00000 0.5952380952380952 - 1.0 - 1.0 - 1.0 ETF 0.5952380952380952 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9285714285714286 0.9285714285714286 0.9285714285714286 0.9285714285714286 0.9285714285714286 none 1.0 2112445 0 0 0 3745738 2568348 0 0 0 0 1808449 2267130 0 0 2001751 3308487 1930921 2078688 0 234794 2667716 0 2144836 0 0 2311620 0 1979675 2017012 2541422 0 2418575 3846040 2321996 0 0 0 0 2250342 0 2657913 1515842 2460690 2280111 0 2070977 0 0 0 2363656 2525996 0 2622143 2501285 2206744 1817817 1857525 1393942 2316514 0 2850782 2316636 2334479 2196160 2067793 2670786 1569945 2383915 1205502 0 2304341 1781166 0 1597077 1226038 2709629 1880779 0 1352030 1811882 0 2873743 0 1689466 0 1955501 1457366 1712186 2614631 0 2302323 2023847 1708788 3344805 0 1832191 1902038 0 2427175 2915148 2167972 1483048 2271902 599847 2386618 0 2199189 2130062 1822801 1729970 0 972342 1555580 2251913 802087 0 827233 1337602 1170030 845273 0 1026160 0 1542279 579726 970327 1270935 0 1250664 515061 804116 701964 741958 895018 1463150 843840 545778 779474 478898 432151 739011 0 821534 1112634 808564 500014 803166 721931 0 956947 706792 686371 1354873 0 1476394 1342255 2962613 1849940 0 1822705 0 1282353 958808 2069779 2768891 0 1254338 2369665 1406407 2741934 1593623 1859209 1240458 1720485 3875974 1480216 1867705 0 981848 2035914 0 2489638 1435161 2346399 910647 1383617 0 1909029 1787874 1708720 -AAEIMDAANNTGNAVK MGYG000000195_00451;MGYG000002040_01210;MGYG000002610_00229;MGYG000002274_00061;MGYG000003899_01644;MGYG000002619_00485;MGYG000003166_01348;MGYG000001255_01101;MGYG000002641_00067 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,3WGPA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 - 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1655930 0 0 0 0 1561677 0 0 0 0 1537864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4115409 0 0 0 0 4812144 0 0 0 0 4149538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1153969 0 0 0 0 907931 0 0 0 0 892446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1330206 0 0 0 0 2149738 0 0 0 0 1032992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2167557 0 0 0 0 2199816 0 0 0 0 1896790 0 0 0 0 0 0 0 0 0 0 -AAEIMDAFNEQGGAYK MGYG000002549_02928;MGYG000000196_03986 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 805358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384343 0 0 0 0 0 0 0 0 0 782736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284495 0 0 0 0 0 0 0 0 0 0 417051 0 0 0 0 0 0 0 0 0 0 0 355478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 551044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEIMDAFNNQGGAFK MGYG000002293_00508 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1570239 0 0 0 0 2382420 0 0 0 0 931745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEIMDAYNNQGGAFK MGYG000003697_01471;MGYG000002834_00437 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,22WEA@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1193749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3164629 0 0 0 0 5171634 0 0 0 0 2402885 0 0 0 0 523684 0 0 0 0 1024416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEIPEAIR MGYG000000136_02061;MGYG000002670_00403;MGYG000001315_01353;MGYG000002234_01458;MGYG000004733_00985;MGYG000003891_01006;MGYG000000252_01802;MGYG000000280_01284;MGYG000000031_02249;MGYG000000142_02050;MGYG000004630_00952;MGYG000002492_00392;MGYG000000135_01188;MGYG000000690_01576;MGYG000000028_01605;MGYG000004689_01598;MGYG000002517_02856;MGYG000000002_00865;MGYG000002966_02558;MGYG000001186_01095;MGYG000000213_00197;MGYG000004296_00406;MGYG000000806_01299;MGYG000002278_02309;MGYG000000050_01189;MGYG000002298_00345;MGYG000000193_02113;MGYG000000201_02098;MGYG000000301_00177;MGYG000004879_01580;MGYG000001338_02790;MGYG000002528_01856;MGYG000000164_02747;MGYG000001689_02303;MGYG000000562_01931;MGYG000000133_00062;MGYG000000212_03064;MGYG000000184_01189;MGYG000003694_02445;MGYG000000216_02346;MGYG000000251_01814;MGYG000001637_00014;MGYG000000187_01741 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.46511627906976744 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 8878471 12981380 11420731 5779481 14960059 13671930 5589446 10509670 7667701 9399786 16602501 10537293 12000748 7250767 11519457 11593081 11659981 13847685 8546997 10386418 10290732 0 12093455 6834263 9762334 7568036 8225575 11267266 0 9266593 7552332 12654357 9093341 8206258 9517302 7102038 7319076 10337782 5404902 17320396 7617030 4398345 7439747 3955187 5006259 5306080 4347654 3680675 6597491 4101590 6627473 3164007 3157720 3762309 0 16656149 3557753 4736490 4042436 2517669 8496236 5861277 4184585 3850812 4564469 13986298 6395676 4674716 21051769 8473774 8744186 6168395 5835446 6411643 4919426 9930961 8521959 23311824 23315387 7978577 9249262 11905362 7882042 11106769 7428451 9209578 12253703 8688789 14454735 8831685 10338720 16589011 13472416 9551108 9939372 9014590 10257867 19316882 12787649 9285449 10636708 8473908 11469937 15582878 10875229 10054464 13670158 20592710 26628171 11650601 10323265 6476039 8811076 19787099 14227363 22072533 9196567 14510948 13643532 7279161 8486700 15326771 12676869 9190185 10149481 9448231 10966574 13901812 14187248 10479504 12104031 9145381 9858316 12258051 8859992 6203372 7184795 6344899 12423857 10907330 12180721 8207599 14327685 12281702 17907112 15265371 11015027 7790451 12268604 11112976 11961339 11249327 16422104 26337965 23669279 16286493 8647461 18759696 23292034 16333399 14917161 26071151 19114264 18665720 12113849 23148707 19229829 15981242 19236577 4355142 17062690 7520687 20750687 17917167 7930845 13658053 17260183 12889422 19309438 7912301 19736981 6658684 22600507 22675540 31062557 20121818 12019187 16649539 14441533 21241226 -AAEIPEAIRK MGYG000000136_02061;MGYG000002670_00403;MGYG000001315_01353;MGYG000002234_01458;MGYG000004733_00985;MGYG000003891_01006;MGYG000000252_01802;MGYG000000280_01284;MGYG000000031_02249;MGYG000000142_02050;MGYG000002492_00392;MGYG000000135_01188;MGYG000000690_01576;MGYG000000028_01605;MGYG000004689_01598;MGYG000002517_02856;MGYG000000002_00865;MGYG000002966_02558;MGYG000001186_01095;MGYG000000213_00197;MGYG000004296_00406;MGYG000000806_01299;MGYG000002278_02309;MGYG000000050_01189;MGYG000002298_00345;MGYG000000193_02113;MGYG000000201_02098;MGYG000000301_00177;MGYG000004879_01580;MGYG000001338_02790;MGYG000002528_01856;MGYG000000164_02747;MGYG000001689_02303;MGYG000000562_01931;MGYG000000133_00062;MGYG000001645_00457;MGYG000000212_03064;MGYG000000184_01189;MGYG000003694_02445;MGYG000000216_02346;MGYG000000251_01814;MGYG000001637_00014;MGYG000000187_01741 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.46511627906976744 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 3702213 5678226 4646806 2659606 7059487 6056282 2259057 4642502 2966131 4490628 6432247 4850365 6096603 3549302 4842878 5033592 3710415 6093738 3876459 4440778 5046326 6432013 5097445 3497848 4360810 3472066 3452837 5366186 3778896 4215637 3618319 5955867 4281218 3649734 4147815 2632721 3704250 5177592 2354350 7217031 3423463 1839257 3432922 1895577 2079407 2150090 2001277 546589 3126170 1759523 3239616 1445550 1488596 779090 1363199 7117020 1646671 2224083 1775666 1379481 3659021 2691415 1711310 1867158 1932019 5370487 3115925 2442528 6737855 3286139 3778785 2572743 2795660 2489210 1845429 4177752 4025978 11206609 11663771 3150217 4986116 5708353 3986591 4840011 3470865 5189319 7052145 5095024 7360676 4618248 4462176 8561197 6468088 4809039 4592623 0 4590252 9490014 6307976 4527585 4857012 3879652 4925081 7331232 5284576 4663494 6574362 9606832 11140113 5499773 4760554 3158716 3750153 9264458 5895884 9854979 4269414 0 6223623 3526012 3483652 6361371 5456331 4486971 5466668 4866377 4492109 6148288 6644962 5706148 5604504 4543017 4818415 5559496 3737704 3238909 0 3574630 4909635 3862357 5587720 4426680 6385224 5995948 9012368 7150159 4619177 3620619 5636714 4717131 6274902 6169574 7236603 12281599 9896214 5692565 4051468 6625383 11090747 6635628 5453472 10122156 8030106 7009427 4328948 9761497 7801394 6615388 7528968 1718831 6424634 2912201 7458218 8367493 2732752 7170470 7798380 7524132 8265693 3139768 8457717 2290888 8097727 9540844 12825831 6364267 7992797 9613383 5300425 6427505 -AAEISADRVEDATTR MGYG000001410_02390 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__Sutterella wadsworthensis_A|m__MGYG000001410 1.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,4PQ3M@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 178647 0 0 74636 0 242494 0 0 0 0 0 0 193171 0 0 0 0 0 0 0 213611 0 0 262120 0 0 0 0 0 0 111672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134223 311104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825172 0 0 1167332 0 1409138 1623165 3009607 1642403 1510966 0 1089583 1911763 0 0 1520870 1276019 0 0 1785816 0 1070299 0 1241927 1450413 1062162 1084310 0 0 1566808 1219400 0 0 1351763 3084280 0 1405090 0 -AAEIYAK MGYG000004296_01529 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Ruminococcus_A|s__Ruminococcus_A faecicola|m__MGYG000004296 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia,3XZJC@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 lacE 1.0 - 1.0 - 1.0 ko:K10188 1.0 ko02010,map02010 1.0 M00199 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.4 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEK(Lys->Asn)VADLEGDEK MGYG000002528_02459 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2681F@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1024272 0 0 0 490521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282771 0 874357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386233 0 0 0 298734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEKFDETR MGYG000002171_02670;MGYG000001787_01249;MGYG000000222_01625;MGYG000002438_00039;MGYG000000322_00356;MGYG000002063_01184;MGYG000004561_00681;MGYG000000044_01844;MGYG000003420_01205;MGYG000001659_01120;MGYG000002922_00071;MGYG000001337_03259;MGYG000000254_00710;MGYG000001360_01047;MGYG000000696_02205;MGYG000001346_01394;MGYG000002218_02323;MGYG000002549_02291;MGYG000000074_01051;MGYG000004797_01692;MGYG000003554_00934;MGYG000002171_01186;MGYG000000236_03660;MGYG000000042_02369;MGYG000001835_01092;MGYG000000196_04898;MGYG000001489_00005;MGYG000003701_00971;MGYG000002033_03235;MGYG000001313_02866;MGYG000003539_01037;MGYG000001783_01115;MGYG000000462_01102;MGYG000000013_04828;MGYG000000215_02858;MGYG000004241_00017;MGYG000004464_00935;MGYG000001661_00506;MGYG000001562_02738;MGYG000002418_01386;MGYG000001780_02752;MGYG000003367_02616;MGYG000002560_03858;MGYG000002455_04389;MGYG000002082_00706;MGYG000002478_03132;MGYG000003282_00840;MGYG000003680_00901;MGYG000003521_01343;MGYG000001789_00637;MGYG000002007_00482;MGYG000004756_00358;MGYG000000003_01643;MGYG000003681_00470;MGYG000002205_01396;MGYG000000243_01020;MGYG000000355_02188;MGYG000001415_00255;MGYG000001750_00580;MGYG000004468_00075;MGYG000003546_00779;MGYG000001302.1_02379;MGYG000002281_02762;MGYG000001655_03175;MGYG000004479_02808;MGYG000003374_01763;MGYG000000781_01995;MGYG000003279_01639;MGYG000003812_01164;MGYG000000224_02424;MGYG000002540_01223;MGYG000000105_02674;MGYG000001599_02329;MGYG000004019_00958;MGYG000003362_02531;MGYG000003423_01692;MGYG000003908_00479;MGYG000003469_01456;MGYG000003812_01753;MGYG000000414_00102;MGYG000000415_01387;MGYG000000053_01058;MGYG000000098_03934;MGYG000001503_01579 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,2FNVQ@200643|Bacteroidia,4AM8U@815|Bacteroidaceae 0.6071428571428571 976|Bacteroidetes 1.0 K 1.0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released 1.0 rpoD 0.9761904761904762 - 1.0 - 1.0 ko:K03086 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03021 1.0 - 1.0 - 1.0 - 1.0 Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 682018 0 919347 888018 714415 555105 0 654456 932095 0 830364 817921 962192 0 0 1107615 0 706022 0 0 0 653914 854987 1101284 0 877119 738730 629147 746858 0 1094915 0 1122497 0 737047 0 582663 587712 773726 0 593479 712214 991777 730141 0 904564 610480 0 1037792 975536 632806 0 0 1034093 0 373418 0 0 0 858188 814747 570498 0 866967 883604 552632 772621 0 761990 0 721369 0 641241 0 736591 845783 443422 0 584173 617161 934914 793639 0 599053 822125 0 821099 592446 608164 0 0 684087 0 1159777 0 0 0 317682 996162 924738 0 854959 495325 991029 622929 0 930422 0 432706 0 387607 0 426971 611816 590843 0 863282 487482 515599 506013 0 502443 416957 0 852211 597851 448609 0 0 570614 0 831705 0 0 0 452746 71845 480949 0 546903 152870 699259 396966 0 455671 0 528571 0 472623 0 477036 552575 848450 0 489721 764849 1086849 886813 0 743319 641821 0 1109016 885178 1307670 0 0 688455 0 688247 0 0 0 783364 601690 846896 0 1186759 610459 633053 878946 0 631817 0 212128 0 1755886 0 1185272 799443 -AAEKIDVDETGKITGLF MGYG000000133_00802 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3XYQR@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 8.87 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1747403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEKIEALGGK MGYG000001310_00106;MGYG000000164_02745;MGYG000003425_03574;MGYG000000249_01532 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WIV7@541000|Ruminococcaceae 0.75 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144015 0 0 0 0 0 0 0 1004805 0 0 0 0 0 0 0 0 0 0 0 0 0 1585744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1017764 0 0 0 0 1128232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188131 0 0 0 0 179887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 824492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99014 0 0 601870 0 0 0 0 0 0 0 0 0 0 0 0 0 404936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258256 -AAEKIEALGGKAEVI MGYG000001310_00106;MGYG000000164_02745;MGYG000000249_01532 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WIV7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 903811 1437248 0 0 0 0 0 0 0 0 1163816 866013 697902 0 0 0 0 1667590 0 720033 1076363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775879 421228 0 0 0 0 0 0 0 0 254031 320337 1696340 0 0 0 0 235018 0 379961 399574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182410 164205 0 0 0 0 0 0 0 0 102538 338562 150055 0 0 0 0 225857 0 133577 198116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80772 789181 0 0 0 0 0 0 0 212970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356367 328962 0 0 0 0 0 0 0 0 262739 310218 0 0 0 0 0 150657 0 364227 125570 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEKLEKEHPGK MGYG000000255_02109 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0683@1|root,COG0683@2|Bacteria,1UHWZ@1239|Firmicutes,25E5X@186801|Clostridia,21ZYF@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Protein of unknown function (DUF3798) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF3798 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 175154 0 0 115242 0 226668 0 159642 0 0 0 0 223447 0 0 0 227912 0 0 200113 0 174718 0 0 0 0 0 0 0 0 151388 280255 0 0 0 111704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 39601 0 0 79008 0 203846 0 188373 0 0 0 0 138368 0 0 0 266976 0 0 140672 0 63438 0 0 0 0 0 0 0 0 119715 328088 0 0 0 0 0 0 270401 0 0 425040 0 466863 0 622457 0 0 0 0 292093 0 0 0 306738 0 0 377825 0 273619 0 0 0 0 0 0 0 0 219902 375928 0 0 0 208676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEKPVETKPAETK MGYG000000031_02551 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066205|m__MGYG000000031 1.0 2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24UU3@186801|Clostridia,3Y0P6@572511|Blautia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEKYNDAR MGYG000001302.1_01986 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAELAFEFLPR MGYG000000262_00363 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,25US3@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 - 1.0 - 1.0 - 1.0 ko:K13921 1.0 ko00640,map00640 1.0 - 1.0 R02377 1.0 RC00087 1.0 ko00000,ko00001 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3787805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14230834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5771148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAELAGNDTIPVEIAR MGYG000002477_00729;MGYG000002494_01504 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,3XN16@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Involved in a late step of protoheme IX synthesis 1.0 hemY 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.0 - 1.0 ko:K02498 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 HemY_N,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309971 0 0 0 0 0 0 0 686047 0 0 1350067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1343650 0 1156723 0 0 0 0 0 0 0 0 708012 0 0 0 0 535364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAELATIEFLK MGYG000002494_02695 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,3XMZQ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 A 1.0 3'-to-5' exoribonuclease specific for small oligoribonucleotides 1.0 orn 1.0 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 1.0 - 1.0 ko:K13288 1.0 ko03008,map03008 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03009,ko03019 1.0 - 1.0 - 1.0 - 1.0 RNase_T 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome biogenesis in eukaryotes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216759 0 169211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2574026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3210970 0 2128366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 508800 0 581103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAELEDEDAIVER MGYG000002050_01431 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900756725|m__MGYG000002050 1.0 COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CUYV@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Methionine synthase vitamin-B12 independent 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Meth_synt_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAELENEDV(Val->Ala)IVER MGYG000004875_00848 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp002232035|m__MGYG000004875 1.0 COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CUYV@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Methionine synthase vitamin-B12 independent 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Meth_synt_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAELFAK MGYG000003694_01610;MGYG000003694_01735 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter faecis|m__MGYG000003694 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 0.5 186801|Clostridia 1.0 C 0.5 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 0.5 nifJ 0.5 - 1.0 1.2.7.1 0.5 ko:K03737 0.5 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 0.5 M00173,M00307 0.5 R01196,R10866 0.5 RC00004,RC02742 0.5 br01601,ko00000,ko00001,ko00002,ko01000 0.5 - 1.0 - 1.0 - 0.5 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 0.5 - 1.0 - 1.0 - 1.0 GT2 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 0.5 0.5 0.5 0.5 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 0.5 none 1.0 0 0 287136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255085 0 0 0 0 0 0 0 0 0 853021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 171082 0 0 328625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2541080 0 0 0 0 0 0 0 0 0 2847200 0 0 0 0 665754 0 0 0 0 1017941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464295 0 0 0 0 375939 0 0 0 0 366531 0 0 0 0 0 0 0 0 0 0 -AAELFAR MGYG000000179_03842;MGYG000003922_00362;MGYG000001065_02072;MGYG000000198_01190;MGYG000001606_00512;MGYG000004087_02250 domain d__Bacteria 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,21YPK@1506553|Lachnoclostridium 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 0.6666666666666666 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 3682456 2005620 1920300 321940 0 0 2324107 0 2856159 0 2134538 2773109 2860868 3659271 3722175 3300982 3011036 0 0 0 4107932 0 0 0 0 910893 3028404 0 3817330 0 1850763 2557376 2206871 2549055 0 3082452 3503750 2165486 2693107 2519795 2606915 1695105 0 0 1905148 1689692 2731345 2963167 1757779 1511367 2464902 2465222 1716558 2051146 2671766 0 2525313 0 2218534 0 0 0 0 1904748 2028163 0 2874469 0 1807029 1800800 2631882 2458958 0 2229308 2031759 3080666 6554241 3411832 3627013 6716645 0 0 3814128 3350434 4355155 4727193 3373220 2507386 3863858 6167377 6272265 5008355 4675248 0 6538794 0 5695053 0 0 0 0 4541890 6587511 0 6465613 0 2696862 2379987 3651768 4645792 0 4600124 4262882 3137963 2584797 2675948 0 2679224 0 0 2754398 3019108 2585514 3577130 3547078 2737340 4423055 2680097 2736327 4128676 3136537 0 0 0 2029798 0 0 0 0 2384138 2535332 0 2848698 0 418162 2655105 5142189 3452851 0 2752923 2395600 4169735 8575802 3318117 5356230 8850006 0 0 9202200 5848521 8410667 9747241 3117196 6245179 2441513 10612906 8824335 3535160 7210025 0 5705203 0 7006187 0 0 0 0 5861241 8779643 0 11607952 0 4667215 2363352 6540537 7736703 0 6926809 6601459 5245034 -AAELGGK MGYG000001675_00492;MGYG000001338_02192 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,36EGU@31979|Clostridiaceae 0.5 186801|Clostridia 1.0 E 0.5 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdh 0.5 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 0.5 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 572062 0 154998 0 0 0 0 0 0 0 0 101326 0 0 866826 0 0 0 0 0 0 290321 0 170842 0 0 0 0 0 0 0 744879 280472 0 0 0 924554 0 650691 0 0 0 0 0 0 0 0 0 0 0 0 0 701403 0 0 0 0 0 0 0 0 0 0 221811 0 0 0 0 0 0 261072 0 0 0 0 842595 0 0 715966 0 0 312667 0 0 0 0 0 412110 0 0 0 0 0 0 0 0 0 310818 0 691823 0 621369 0 0 0 0 0 291759 485140 0 0 0 428927 365908 868799 0 986037 0 0 108360 0 0 0 0 0 564443 0 0 279971 0 0 0 0 0 0 537850 0 566716 0 0 0 0 0 0 0 782606 76504 0 0 0 777090 672759 737503 0 115846 0 0 198558 0 0 0 0 0 0 0 0 895615 0 0 0 0 0 0 731835 0 291397 0 980448 0 0 0 0 0 413438 955314 0 0 0 976685 539227 -AAELGYR MGYG000002517_03141 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Phosphotransferase System 1.0 fruA 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 GGDEF,PTS_EIIA_2,PTS_EIIC,PTS_IIB,Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS);Metabolic pathways;Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 152249 0 0 0 0 0 0 0 179626 0 322778 0 0 0 265375 0 0 0 278282 0 0 0 0 0 0 662639 258395 0 0 0 0 0 0 0 0 430545 335433 0 582439 0 0 0 0 0 0 0 0 0 274274 0 0 0 245786 0 0 0 0 0 0 0 0 0 0 263152 392721 0 0 0 0 0 0 0 0 0 500701 0 275263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248729 0 1019067 0 0 0 0 0 0 0 1217781 0 450633 0 0 0 1363061 0 0 0 960666 0 0 0 0 0 0 1076523 1102913 0 0 0 0 0 0 0 0 910552 1110635 0 963236 0 0 0 0 0 0 0 965570 0 1467538 0 0 0 1190375 0 0 0 1041133 0 0 0 0 0 0 1265957 886639 0 0 0 0 0 0 0 0 1525392 1194711 0 -AAELIDMR MGYG000000074_00268 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,2FMWT@200643|Bacteroidia,22U9H@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Formiminotransferase domain, N-terminal subdomain 1.0 ftcD 1.0 - 1.0 2.1.2.5,4.3.1.4 1.0 ko:K00603,ko:K13990 1.0 ko00340,ko00670,ko01100,map00340,map00670,map01100 1.0 - 1.0 R02287,R02302,R03189 1.0 RC00165,RC00221,RC00223,RC00688,RC00870 1.0 ko00000,ko00001,ko01000,ko03036,ko04147 1.0 - 1.0 - 1.0 - 1.0 FTCD,FTCD_C,FTCD_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate formimidoyltransferase. | formimidoyltetrahydrofolate cyclodeaminase. glutamate formyltransferase. | formiminotetrahydrofolate cyclodeaminase. The enzymes also catalyzes formyl transfer from 5-formyltetrahydrofolate to L-glutamate.-!-In eukaryotes, it occurs as a bifunctional enzyme that also has formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) activity.-!-Formerly EC 2.1.2.6. | In eukaroytes, occurs as a bifunctional enzyme that also has EC 2.1.2.5 activity. 5-formimidoyltetrahydrofolate + L-glutamate = (6S)-5,6,7,8- tetrahydrofolate + N-formimidoyl-L-glutamate. | 5-formimidoyltetrahydrofolate + 2 H(+) = (6R)-5,10- methenyltetrahydrofolate + NH4(+). 1.0 1.0 1.0 1.0 One carbon pool by folate;Metabolic pathways;Histidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 594296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746954 0 0 0 0 0 0 0 0 -AAELIR MGYG000002033_00724;MGYG000001300_00650;MGYG000002438_02893;MGYG000004019_01436;MGYG000004797_03900;MGYG000001489_04896;MGYG000000243_00603;MGYG000004464_00649;MGYG000001789_02010 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,22W81@171551|Porphyromonadaceae 0.4444444444444444 976|Bacteroidetes 0.8888888888888888 C 0.8888888888888888 Electron transfer flavoprotein 0.4444444444444444 etfB 0.8888888888888888 - 1.0 - 0.8888888888888888 ko:K03521 0.8888888888888888 - 0.8888888888888888 - 0.8888888888888888 - 0.8888888888888888 - 0.8888888888888888 ko00000 0.8888888888888888 - 1.0 - 1.0 - 1.0 ETF 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 none 1.0 0 0 3597507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2609688 0 0 0 0 2266343 0 0 0 3964851 0 0 0 2779889 0 2255104 0 0 0 617242 0 0 0 0 0 0 0 2127646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1996689 0 0 0 0 0 0 0 0 0 0 0 0 1990201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1840453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2357610 0 0 0 0 0 0 0 0 0 0 0 0 -AAELLAEGK MGYG000001311_03460;MGYG000000255_02050;MGYG000000179_04958 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,2682U@186813|unclassified Clostridiales 0.6666666666666666 186801|Clostridia 1.0 G 0.6666666666666666 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 1669875 0 917882 0 0 0 351219 0 1560531 1466617 0 0 0 1912184 0 0 1172919 0 1788451 1803544 2149378 0 0 0 0 1815685 265148 0 475587 1426536 0 0 1282311 627140 0 1530075 1000725 561883 1076119 0 853859 0 0 0 724572 0 1197600 801769 0 0 0 999350 818841 0 641751 0 863660 931373 774770 0 0 0 0 827214 777311 0 1765659 787644 0 0 717240 720615 0 797094 951534 386263 2641489 0 1904029 0 0 0 1957269 0 2592450 2016617 0 0 0 2798611 2201305 0 2283516 0 2270627 2470255 2257137 0 0 0 0 1761492 2219018 0 2933768 2402019 0 0 1801922 1835521 0 2498450 1957076 1851244 1620104 0 1695011 0 0 0 1352327 0 1562212 1895359 0 0 0 1576368 1264413 0 1704713 0 1400402 1666567 1274651 0 0 0 0 1148810 1370047 0 1605984 683766 0 0 1473637 0 0 1272230 1294366 1662167 2798005 0 2013182 0 0 0 2541905 0 2395289 2907349 0 0 0 3463051 2984428 0 2661327 0 2511908 2206641 2390767 0 0 0 0 2971450 2563330 0 3120348 1479779 0 0 2083420 2334425 0 3995558 2025616 1951610 -AAELLDYVR MGYG000002438_02041 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes,2G0HK@200643|Bacteroidia,2324C@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 462783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1598202 0 0 0 0 0 0 0 0 1428396 0 0 0 0 0 0 0 0 989791 0 777357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670142 0 0 0 0 0 0 0 0 1021114 0 0 0 0 0 0 0 0 347879 0 854169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAELLR MGYG000002438_02893;MGYG000001300_00650;MGYG000004797_03900;MGYG000000042_01534;MGYG000000423_01318;MGYG000000243_00603;MGYG000000354_00400;MGYG000003701_04105;MGYG000000170_02403;MGYG000001789_02010;MGYG000001783_00812;MGYG000002033_00724;MGYG000000262_01672;MGYG000001655_00932;MGYG000003504_00715;MGYG000001787_00188;MGYG000004464_00649;MGYG000000301_01699;MGYG000000133_02950 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,22W81@171551|Porphyromonadaceae 0.3157894736842105 976|Bacteroidetes 0.6842105263157895 C 0.6842105263157895 Electron transfer flavoprotein 0.3684210526315789 etfB 0.6842105263157895 - 1.0 - 0.8421052631578947 ko:K03521 0.6842105263157895 - 0.8421052631578947 - 0.8947368421052632 - 0.8421052631578947 - 0.8421052631578947 ko00000 0.6842105263157895 - 1.0 - 1.0 - 1.0 ETF 0.6842105263157895 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8421052631578947 0.8421052631578947 0.8421052631578947 0.8421052631578947 0.8421052631578947 none 1.0 0 0 0 2122860 0 0 2411669 1625579 2175771 1532209 0 0 3324819 2609894 0 0 0 0 2011877 1630611 0 0 0 2935984 2172621 0 0 0 0 0 0 0 0 0 0 2363208 0 4272886 0 0 372961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1038072 0 0 0 0 0 2085259 0 0 1964959 0 0 0 0 0 0 0 1477213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604786 0 0 237196 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1454422 0 0 0 0 0 954455 0 0 0 0 0 1143224 0 0 0 0 665932 0 0 0 0 0 0 0 0 0 903267 492605 0 0 682878 0 0 0 0 557091 -AAELNQVPYYSR MGYG000002478_00646 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 2DBBS@1|root,2Z89P@2|Bacteria,4NG8V@976|Bacteroidetes,2FPGU@200643|Bacteroidia,4ANVA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like,SusD-like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 240080 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 967167 1633324 1225709 888796 0 0 1363922 0 933595 0 888388 0 0 1367528 0 639283 1198578 0 0 757780 979054 735606 0 0 746204 920197 1146486 1201534 0 0 1290761 0 0 1183982 0 758015 0 0 604528 567409 1153893 886478 0 0 448065 0 563088 0 901968 0 0 804366 0 1183479 713579 0 0 621045 989288 1070412 0 0 770283 1071221 719256 713158 0 0 519206 0 0 1121463 0 699950 0 0 1453883 444871 1242282 743085 0 0 434342 0 563543 0 643705 0 0 836374 0 1596069 0 0 0 1431435 2142726 1042759 0 0 277281 0 795416 229148 0 0 889251 0 0 532419 0 1114294 0 0 389042 413169 0 337251 0 0 0 0 610146 0 575022 0 0 299419 0 0 517997 0 0 395582 0 659517 0 0 431232 0 895766 0 0 0 902090 0 0 304460 0 293908 -AAELQYGELPR MGYG000000301_00104;MGYG000000133_01006 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WH14@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 - 1.0 - 1.0 ko:K03695,ko:K03696 1.0 ko01100,ko04213,map01100,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N,UVR 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways;Longevity regulating pathway - multiple species 1.0 none 1.0 0 528275 347967 346129 0 0 0 0 0 0 0 0 208464 0 0 476039 0 0 0 0 0 389111 0 652970 0 0 0 0 0 0 502653 680440 529398 0 0 0 0 384649 0 280382 353591 331894 0 280795 0 0 0 0 0 0 198514 0 0 348662 0 0 0 0 0 241199 0 0 0 0 0 0 0 0 234450 0 0 0 0 0 0 329395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1772670 751652 997787 0 384433 0 0 0 0 0 0 813503 976404 0 1305118 0 0 0 0 0 1257208 0 957982 0 0 0 0 0 0 384045 1128906 1744609 0 0 0 0 427592 -AAELSGDFAELMKLADK MGYG000003221_00300 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__OM05-12|s__OM05-12 sp900760755|m__MGYG000003221 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 778135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAELSGDFAK MGYG000001306_00064 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3131077 0 0 0 0 2110185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1479630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAELTR MGYG000000196_03698;MGYG000001666_00068;MGYG000001378_01448;MGYG000000243_01648;MGYG000002171_00496 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,2FMMW@200643|Bacteroidia 0.8 976|Bacteroidetes 1.0 G 1.0 glucuronate isomerase 0.8 uxaC 0.8 - 1.0 5.3.1.12 0.8 ko:K01812 0.8 ko00040,ko01100,map00040,map01100 0.8 M00061,M00631 0.8 R01482,R01983 0.8 RC00376 0.8 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 UxaC 0.8 - 1.0 - 1.0 - 1.0 - 1.0 glucuronate isomerase. uronic isomerase. Also converts D-galacturonate to D-tagaturonate. D-glucuronate = D-fructuronate. 0.8 0.8 0.8 0.8 Pentose and glucuronate interconversions;Metabolic pathways 0.8 none 1.0 0 0 0 1277643 0 0 1134098 0 1724931 1382397 0 0 0 917379 1323701 0 0 0 0 0 0 0 0 0 0 0 1949558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1228203 0 0 1093046 0 947021 1288260 0 0 0 1417421 356054 0 0 0 0 0 0 0 0 0 0 0 1533591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257228 0 0 114218 0 713241 335748 0 0 0 869520 357968 0 0 0 0 0 0 0 0 0 0 0 1175684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1477229 0 0 1420829 0 1292091 745512 0 0 0 883662 431232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1237787 0 0 964713 0 0 0 1056173 953833 0 0 0 0 0 0 0 0 0 0 0 1449826 0 0 0 0 0 0 0 0 0 0 0 -AAELVQALK MGYG000000087_01479;MGYG000000198_02625 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,21YF6@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 499920 0 0 399129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281632 0 0 0 0 0 0 0 0 0 0 273951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249915 0 0 208440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAELYKPFIIR MGYG000004797_04274;MGYG000001306_02654;MGYG000004561_01031;MGYG000000236_01798;MGYG000003693_02792;MGYG000002556_01323;MGYG000002478_00805;MGYG000001313_00088;MGYG000003374_00512 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81265 0 0 0 0 154852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417512 0 0 0 0 725220 0 0 0 0 528273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 206995 0 0 0 0 169804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88996 0 0 0 0 125050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222969 0 0 0 0 132010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEM(Met->Glu)NMPVER MGYG000002517_00980 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth 1.0 sigA 1.0 - 1.0 - 1.0 ko:K03086 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03021 1.0 - 1.0 - 1.0 - 1.0 Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1336192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 651621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 831982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2204344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 716227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEM(Oxidation)AATC(Carbamidomethyl)TDPVR MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 637150 1364065 745454 133042 1421562 1017507 0 889797 484438 857479 797095 680719 1713761 565355 1212470 3062098 1309766 0 915117 871334 570877 2400743 0 301186 863008 500175 386571 0 365118 556605 598704 1186692 395457 640642 412555 340874 390260 648134 1307390 1634987 0 817196 522417 689521 2181276 956080 2575821 670926 366443 675750 508666 507695 670584 157591 457236 0 905674 1571061 673498 472411 0 1388446 664288 1002217 1036682 0 1665406 703897 1582559 702055 334783 1516828 962937 1435989 1227631 627913 3988651 11812878 1113989 6856483 1016479 4172778 984192 3628160 1545152 3677743 1124393 2195616 3000995 3229279 4046380 3258500 3083856 0 4067119 4374083 2887848 5517012 0 2461739 4670496 3656170 4610673 0 675598 2726727 1184370 3949173 2047783 4324967 4764334 1359117 2999171 1019622 1887260 2020168 1223319 2560917 1590619 2192054 2649609 1544615 1442350 3555502 1402166 1117404 2158440 2144740 1733563 3087461 2431719 0 973896 2837189 1314039 1925983 0 2022265 1363292 777044 1895948 0 2374091 1485443 1409482 1372411 1549550 842804 1286218 1137146 908274 1288265 905366 1316966 1666660 1452951 2544964 1331405 1005714 1023417 995131 1333118 2689760 1279285 2730545 1172385 1247537 2117269 839772 0 1137643 1425125 801436 1772111 0 1596140 1354697 1673670 1263626 0 260919 1146666 2346809 1633839 2555189 1282646 1505345 1509593 1794762 1879893 -AAEM(Oxidation)AATC(Carbamidomethyl)TDPVRK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 236857 0 0 0 303737 0 179076 177932 173701 255267 0 369057 0 292618 938229 0 0 106477 325824 0 103229 0 0 196155 148034 0 0 0 0 0 386109 0 0 0 0 231392 274853 250402 365599 0 84386 0 171027 0 186235 538458 0 148442 0 0 208824 244209 0 0 0 129458 301254 0 0 0 323754 229640 155070 187015 0 0 0 0 90614 0 254897 291513 0 309186 0 1024866 2457122 204858 1175769 0 1242795 0 977115 438622 913639 242201 0 897848 859324 1016660 1018442 0 0 1078039 1212535 802373 1447986 0 540057 1128169 839963 760153 0 0 0 0 530370 554880 1154439 1059966 0 1074467 0 499869 384024 150350 556073 0 399317 0 340849 165812 610770 250966 0 370578 336237 0 580882 0 0 0 349534 133730 534533 0 379402 0 108298 275839 0 0 0 0 98395 550933 0 143632 0 0 367338 261601 267158 361992 277832 0 289975 0 141328 218378 237530 482421 0 520642 364086 271441 340582 0 0 252079 532457 0 331091 0 298024 294232 233316 168342 0 0 0 0 341716 471923 275462 299925 0 367493 436686 -AAEMAAN(Deamidated)LKPGEVMLLENLR MGYG000000074_02205 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,22UY0@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 48916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEMAATC(Carbamidomethyl)TDPVR MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 4848364 12519848 6902606 2593894 11181763 8175882 723189 7145550 2729799 6806702 6035253 6471701 11626039 3922466 7198047 10851839 4474640 0 6666564 6985287 4483886 11055031 0 2598580 7204431 3594625 3662852 0 3180637 3802476 3367531 9862548 4280315 4512217 4155916 2342793 2874511 4759579 15606924 15579945 3014269 8894575 4533341 7711306 25851789 9430359 9147738 6620102 3663094 4498382 5777079 6275171 8060691 2864121 5889425 0 13037907 17446116 8981920 6210795 0 14572066 9596861 10194741 10309817 0 19631262 7141278 10675086 6492717 3646347 13453491 10796680 15872101 10281955 3948006 34175803 37508260 7331492 41861599 4355514 27891079 7284479 26430166 11045220 25627267 10835621 15421803 24711774 21508737 37058398 24341755 21784273 0 34838571 39203463 24426938 47416241 0 17925597 42613578 29621973 37155248 0 6133672 20615843 7311560 28111656 14681615 34855712 32430149 8946713 23027855 5779403 15470313 15600272 8139840 19454848 13988926 19088089 23508200 12976159 11460395 24874011 10056071 6040126 17079682 13451114 11450080 27754831 21727054 0 8305093 23080440 10400350 12293071 0 11789050 11742536 5714161 14568042 0 15632593 12255374 8489705 9874783 13141288 5579877 12145193 9874320 7330831 9538297 9418074 12438857 18519999 10089904 371155 11652930 6428220 9758661 8086820 9877850 16074333 10471096 13629797 8062332 10606792 18191932 9912747 0 9522380 11618840 6597296 14331498 0 10011931 9506594 15164098 11155739 0 3150880 10090039 21935413 12723846 24030921 12636853 8612046 9905869 14007091 16788977 -AAEMAATC(Carbamidomethyl)TDPVRK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 904940 2454838 1324573 598789 1546714 1555399 180695 1388551 0 1397336 1024207 0 2304689 747002 1200903 1821167 792543 0 1406845 1355281 939644 2130819 0 765294 1425484 834138 745343 0 186924 776783 671836 1435023 728228 915879 733757 487357 645027 935653 3021001 2318718 489504 1491629 866731 1511376 3773221 1649873 0 1342711 601814 0 1260603 1213380 1629020 580320 1045478 0 2015130 2756034 1934244 953772 0 2802120 1551929 1736747 1644865 0 2947585 1310104 1701358 1090311 698540 2323285 858112 2799398 1883728 666332 5917817 5486286 1266292 6922010 628589 4749716 1275452 6039794 0 5037197 1691835 0 4002855 3191378 5143410 3714925 4116413 0 6176491 5762671 3924410 6674881 0 3773647 6474287 5692759 7193891 0 1105040 3622417 1390617 5181585 2555336 6255483 3982355 1887886 3908403 1068474 2571417 1812985 1164853 2435196 1650429 2065279 3035233 1786063 0 3034367 1661637 0 2976477 2353378 1728671 3020141 1824694 0 1255632 2884491 1419875 1745022 0 1127581 1930978 935943 2202099 0 1545632 1780112 1038059 1426111 1564471 1008312 1749571 1615385 1219719 566954 2320649 2944503 3508872 2149836 4900512 2375311 1554944 2128141 0 2621793 3486397 0 2854851 944683 2274099 3935006 2148780 0 2161340 2270261 1390659 2911929 0 2186832 2108638 2842785 2050278 0 445469 2296408 4412309 2853943 3457978 2744981 1390617 2735108 2406424 3486390 -AAEMIAEAQYR MGYG000000074_00673;MGYG000002082_00353 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,2G3E7@200643|Bacteroidia,22UFS@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1094902 0 1962265 0 716178 673255 0 0 0 2220412 1466387 0 1109929 0 0 615901 933104 0 1409537 0 0 975538 0 1751192 885060 941776 0 0 934906 1096758 0 0 1225927 0 0 0 1172521 1915905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 419553 0 0 0 0 525186 416768 0 0 0 368443 0 0 0 0 0 352931 517365 0 742476 353725 0 393801 0 0 0 400498 0 0 534473 0 0 0 374425 0 0 0 409770 0 1595354 0 1406107 0 1994403 1935810 0 0 0 1614403 1041550 0 1481392 0 0 1744360 1661214 0 2257869 3367820 0 1536371 0 1505460 1553019 1635745 0 0 1605129 2409270 0 0 684352 0 0 1596918 2280457 2138477 -AAEN(Deamidated)GVELLYVNTAK MGYG000002966_03539;MGYG000002298_00579 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,248JR@186801|Clostridia,36H91@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 PFAM Alcohol dehydrogenase 1.0 - 1.0 - 1.0 - 1.0 ko:K19956 1.0 ko00051,map00051 1.0 - 1.0 R03234 1.0 RC00089 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 1940433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1789810 0 672112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 622861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2043407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1388429 0 1594428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAENAEGRPERPK MGYG000002517_01672 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 144732 0 0 0 0 0 0 51945 0 0 0 0 0 0 425449 0 0 0 0 0 0 0 0 0 541440 55095 43729 0 0 0 0 0 0 0 0 22449 74746 0 66001 0 0 0 0 0 0 129383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 52976 2351094 0 0 0 0 0 0 0 0 144889 88879 0 0 0 0 0 0 0 0 54165 0 0 0 0 0 0 23033 0 0 0 0 0 0 0 0 0 107625 28072 67584 0 0 0 0 0 0 0 0 37398 86208 0 448007 0 0 0 0 0 0 765483 0 0 0 0 0 0 727983 0 0 0 0 0 0 0 0 0 828044 517692 792678 0 0 0 0 0 0 0 0 379127 502080 0 255443 0 0 0 0 0 0 408560 0 0 0 0 0 0 370192 0 0 0 0 0 0 0 0 0 402281 505984 115853 0 0 0 0 0 0 0 0 722756 544528 0 -AAENFQMFQDK MGYG000000781_02550;MGYG000004876_03507;MGYG000004797_01909;MGYG000002478_03727;MGYG000002455_04589 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,4AKZ7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Conserved protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1015 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1139469 974621 552510 1366718 0 1110840 1520270 150966 1201148 0 0 849734 0 0 0 0 939219 245918 1076005 1093821 1188443 803559 327017 1380196 1069047 1175796 1431125 417771 1230251 987311 1343678 0 653928 0 0 1433527 1062627 652944 996231 846933 933924 1350033 0 0 1206165 946359 822395 0 0 1083442 0 1186212 0 0 747689 1103163 1705525 637123 709648 0 0 0 675864 0 935367 1224362 606315 0 0 0 814086 0 0 845043 0 0 548192 0 0 568807 0 0 989251 0 834774 0 0 730395 0 732952 0 0 448352 0 287793 576624 523789 0 0 0 669669 0 526272 0 558394 0 566539 0 0 233766 0 807049 371612 495714 444020 0 495212 176375 0 0 617252 0 490223 0 0 207899 0 357884 0 0 363831 0 658898 315454 664088 0 0 316583 496166 396034 521322 404249 302537 303194 340735 0 0 0 0 736679 319583 467631 981433 315133 619624 571917 0 867307 1036898 1583446 908276 0 0 604113 0 583934 0 0 680703 2274001 1542416 1578949 0 1002687 1939995 700760 1000111 936665 472730 1801417 836495 491529 495566 0 389557 1615422 0 600884 845901 712648 -AAENFR MGYG000000243_00365;MGYG000001789_00953;MGYG000000236_01636;MGYG000001346_03052;MGYG000001337_02576 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,4AKZ7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Conserved protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1015 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 828610 0 1330643 0 1228911 0 0 0 0 1251966 0 0 0 661150 0 1403392 0 0 557296 0 0 0 0 594181 0 0 1094121 0 0 0 0 0 0 0 0 0 0 0 915706 0 1199999 0 1282279 0 0 0 0 1469906 0 0 0 0 0 1092200 0 0 0 0 0 0 0 0 0 0 759785 0 0 0 0 0 0 0 0 0 0 0 994752 0 955289 0 1356161 0 0 0 0 1105847 0 0 0 512330 0 1029232 0 0 1240649 0 0 0 0 1542095 0 0 1541957 0 0 0 0 0 0 0 0 0 0 0 303755 0 572842 0 515855 0 0 0 0 527768 0 0 0 450845 0 633391 0 0 205083 0 0 0 0 360128 0 0 642117 0 0 0 0 0 0 0 0 0 0 0 518879 0 842127 0 565137 0 0 0 0 536954 0 0 0 441481 0 623623 0 0 314473 0 0 0 0 192549 0 0 446902 0 0 0 0 0 0 0 -AAENFR(Arg->Gln)MFQDK MGYG000000243_00365 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,4AKZ7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Conserved protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1015 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 1216570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAENGVELLYVNTAK MGYG000002966_03539;MGYG000002298_00579 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,248JR@186801|Clostridia,36H91@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 PFAM Alcohol dehydrogenase 1.0 - 1.0 - 1.0 - 1.0 ko:K19956 1.0 ko00051,map00051 1.0 - 1.0 R03234 1.0 RC00089 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 2422529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2544971 0 961528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 597105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2280954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAENTASVMPGYTHLQR MGYG000001300_00033 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,3WGBU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 argininosuccinate lyase 1.0 argH 1.0 - 1.0 4.3.2.1 1.0 ko:K01755 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 1.0 M00029,M00844,M00845 1.0 R01086 1.0 RC00445,RC00447 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ASL_C2,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 argininosuccinate lyase. omega-N-(L-arginino)succinate arginine-lyase. - 2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 486248 0 0 0 0 0 0 0 0 0 0 560620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAENVQESTYAR MGYG000001421_01835 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__Dielma|s__Dielma fastidiosa|m__MGYG000001421 1.0 COG0747@1|root,COG0747@2|Bacteria 1.0 2|Bacteria 1.0 E 1.0 dipeptide transport 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116455 0 0 0 0 0 0 0 0 130356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 870617 0 0 0 0 0 0 0 0 617978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2046111 0 0 0 0 0 0 0 0 2594694 0 0 0 0 0 0 0 0 -AAEPASC(Carbamidomethyl)PK MGYG000001789_01036;MGYG000000042_00377;MGYG000001783_02237;MGYG000000196_01365;MGYG000003363_02568;MGYG000002560_00879;MGYG000003202_01810;MGYG000000243_03283;MGYG000002478_02582 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1350@1|root,COG1350@2|Bacteria,4PKSY@976|Bacteroidetes,2FMFD@200643|Bacteroidia,4AN0W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine 1.0 trpB 1.0 - 1.0 4.2.1.20 1.0 ko:K06001 1.0 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 1.0 M00023 1.0 R00674,R02340,R02722 1.0 RC00209,RC00210,RC00700,RC00701,RC02868 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PALP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 tryptophan synthase. tryptophan synthetase. The alpha-subunit catalyzes the conversion of 1-C-(indol-3- yl)glycerol 3-phosphate to indole and D-glyceraldehyde 3-phosphate (this reaction was listed formerly as EC 4.1.2.8).-!-The indole migrates to the beta-subunit where, in the presence of pyridoxal 5'-phosphate, it is combined with L-serine to form L-tryptophan.-!-In some organisms this enzyme is part of a multifunctional protein that also includes one or more of the enzymes EC 2.4.2.18, EC 4.1.1.48, EC 4.1.3.27 and EC 5.3.1.24.-!-In thermophilic organisms, where the high temperature enhances diffusion and causes the loss of indole, a protein similar to the beta subunit can be found (EC 4.2.1.122).-!-That enzyme cannot combine with the alpha unit of EC 4.2.1.20 to form a complex. (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan. 1.0 1.0 1.0 1.0 Metabolic pathways;Phenylalanine, tyrosine and tryptophan biosynthesis;Glycine, serine and threonine metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 739323 0 736806 0 0 0 0 0 0 0 474496 0 0 625329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 647320 0 0 0 0 956344 0 0 252892 0 0 0 0 0 0 0 0 0 489012 0 0 367451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188352 0 0 0 0 141595 0 0 272570 0 265014 0 0 0 0 0 0 0 414819 0 0 439837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163027 0 0 0 0 260244 0 0 240318 0 294021 0 0 0 0 0 0 0 206450 0 0 354521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204269 0 0 0 0 198867 0 0 0 0 305711 0 0 0 0 0 0 0 512310 0 0 476800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215613 -AAEPFAVEVK MGYG000001378_04614 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2FQVZ@200643|Bacteroidia,4APF4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 D 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 270485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 616412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6958364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13894059 0 13676602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEPVKAEKPAAK MGYG000001300_02529 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG3940@1|root,COG3940@2|Bacteria,1VAX9@1239|Firmicutes,24NY2@186801|Clostridia,3WKE6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Ricin-type beta-trefoil 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 RicinB_lectin_2 1.0 - 1.0 CBM13 1.0 CBM13 1.0 CBM13 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 406539 297198 0 0 237804 0 0 0 0 0 0 0 0 0 0 0 0 531529 0 0 0 0 264546 0 0 0 0 0 0 0 329616 0 0 0 0 387714 0 0 619630 658525 0 0 998812 0 0 0 0 0 0 0 0 0 0 0 0 528211 0 0 0 0 742004 0 0 0 0 0 0 0 495732 0 0 0 0 591707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527180 0 0 0 243318 0 0 0 0 0 0 0 0 0 0 0 0 148487 0 0 0 0 430308 0 0 0 0 0 0 0 416915 0 0 0 0 446643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEQGYIDEIILPK MGYG000003693_02732;MGYG000000042_01219;MGYG000001306_00284 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FNCD@200643|Bacteroidia,4ANBE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 2.1.3.15,6.4.1.3 1.0 ko:K01966 1.0 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 1.0 M00373,M00741 1.0 R01859 1.0 RC00097,RC00609 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 GH101 1.0 acetyl-CoA carboxytransferase. | propionyl-CoA carboxylase. PCCase. The enzyme catalyzes the transfer of a carboxyl group carried on a biotinylated biotin carboxyl carrier protein (BCCP) to acetyl-CoA, forming malonyl-CoA.-!-In some organisms this activity is part of a multi-domain polypeptide that includes the carrier protein and EC 6.3.4.14 (see EC 6.4.1.2).-!-Some enzymes can also carboxylate propanonyl-CoA and butanoyl-CoA (Cf. EC 6.4.1.3). | Also carboxylates butanoyl-CoA and catalyzes transcarboxylation. acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)- biotinyl-L-lysyl-[protein]. | ATP + hydrogencarbonate + propanoyl-CoA = (S)-methylmalonyl-CoA + ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1482622 0 0 0 0 1769169 0 0 0 0 1355831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEQLEK MGYG000002506_04140;MGYG000002366_03975;MGYG000002494_02911 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0176@1|root,COG0303@1|root,KOG2371@2759|Eukaryota,KOG2772@2759|Eukaryota,3AHVW@33154|Opisthokonta,3BZ72@33208|Metazoa,3DEMK@33213|Bilateria,40QWN@6231|Nematoda,1M0KR@119089|Chromadorea,4171K@6236|Rhabditida 1.0 2759|Eukaryota 1.0 G 1.0 Transaldolase/Fructose-6-phosphate aldolase 1.0 CNX1G 1.0 - 1.0 2.10.1.1,2.2.1.2,2.7.7.75 1.0 ko:K00616,ko:K13168,ko:K15376 1.0 ko00030,ko00790,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04727,map00030,map00790,map01100,map01110,map01120,map01130,map01200,map01230,map04727 1.0 M00004,M00007 1.0 R01827,R09726,R09735 1.0 RC00002,RC00439,RC00604,RC03462 1.0 ko00000,ko00001,ko00002,ko01000,ko03041 1.0 - 1.0 - 1.0 - 1.0 AIRS,DRY_EERY,DUF1244,MoCF_biosynth,MoeA_C,MoeA_N,PgpA,Proteasome,RecA,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 molybdopterin molybdotransferase. | transaldolase. | molybdopterin adenylyltransferase. glycerone transferase. Catalyzes the insertion of molybdenum into the ene-dithiol group of molybdopterin.-!-In eukaryotes this reaction is catalyzed by the N-terminal domain of a fusion protein whose C-terminal domain catalyzes EC 2.7.7.75. | Catalyzes the activation of molybdopterin for molybdenum insertion.-!-In eukaryotes, this reaction is catalyzed by the C-terminal domain of a fusion protein that also includes EC 2.10.1.1.-!-Formerly EC 2.7.7.n5. adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin. | D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | ATP + H(+) + molybdopterin = adenylyl-molybdopterin + diphosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;GABAergic synapse;Carbon metabolism;Metabolic pathways;Folate biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 671665 0 903330 1360890 0 1271058 0 0 1154508 0 945631 843661 0 0 1216502 0 1381882 469106 1367368 2368000 0 0 0 1269888 0 0 1328544 1394275 0 0 0 1318174 0 0 1418333 1033914 3349097 0 5151285 0 5547514 7665139 0 3949425 3151246 4365370 2480944 0 3532335 3858964 0 0 6409678 0 6383722 3025202 4686402 8832366 0 7855329 0 4076028 0 0 5533795 4428401 3621769 0 3412713 4123210 0 0 2553917 0 1266657 0 795804 0 973981 1780937 0 2030593 1014932 1693553 741280 0 1404321 1229429 0 0 1176093 0 1525301 2184207 1937538 2114207 0 2620483 0 1211708 0 0 2018302 805414 935042 0 1390778 1868617 0 0 1300363 985929 0 0 0 0 0 1432533 0 1927431 0 0 0 0 921872 1080457 0 0 0 0 0 0 873180 2267279 0 1403466 0 0 0 0 0 0 1099301 0 0 0 0 0 0 1304761 1220404 0 814416 0 492564 477767 0 662305 1103587 923837 787201 0 915961 1896343 0 0 0 0 740979 0 1187823 0 0 953089 0 1480318 0 0 1741255 931697 974596 0 864979 1023590 0 0 0 874064 -AAEQLGEENLPK MGYG000000036_00872 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Pseudoruminococcus|s__Pseudoruminococcus massiliensis|m__MGYG000000036 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEQLIR MGYG000002494_00656 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2980@1|root,COG2980@2|Bacteria,1N0JN@1224|Proteobacteria,1SAG4@1236|Gammaproteobacteria,3ZK9E@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 M 1.0 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane 1.0 lptE 1.0 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 1.0 - 1.0 ko:K03643 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.42.1 1.0 - 1.0 iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788 1.0 LptE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1836234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1230897 0 0 0 0 0 0 0 0 0 1500987 1198953 0 0 1140791 0 0 0 0 1928153 0 0 1425583 0 0 0 0 0 0 0 0 0 0 0 0 0 1260004 0 1516426 0 0 0 0 0 0 0 0 0 1343501 1451915 0 0 0 0 0 0 0 1331555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 917498 0 1059297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1176452 0 0 0 0 0 0 0 0 0 0 0 722493 1228813 0 0 0 0 0 0 0 0 -AAEQPGVK MGYG000004526_01663 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-103|s__CAG-103 sp000432375|m__MGYG000004526 1.0 COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,22ICD@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate:ferredoxin oxidoreductase core domain II 1.0 vorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00174 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFOR_II,POR_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEQYDGK MGYG000002517_01705 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 basic membrane 1.0 tmpC 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573930 0 0 0 0 0 0 0 0 0 0 474821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEQYPDIK MGYG000001300_01299 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,3WJKQ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 basic membrane 1.0 tmpC 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313261 0 293546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1408671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1642456 0 1660270 0 0 0 0 0 0 2266201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEQYVIDEYSK MGYG000002494_02584 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,3XN7Y@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family 1.0 fdhF 1.0 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704 1.0 1.17.1.9,1.17.99.7 1.0 ko:K00123,ko:K22015 1.0 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 1.0 - 1.0 R00519 1.0 RC02796 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECBD_1354.ECBD_3953 1.0 Fer2_4,Fer4,Fer4_6,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate dehydrogenase. | formate dehydrogenase (acceptor). NAD(+)-formate dehydrogenase. | formate dehydrogenase O. The enzyme from most aerobic organisms is devoid of redox-active centers but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centers, flavin and a molybdenum center.-!-Together with EC 1.12.1.2, forms a system previously known as formate hydrogenlyase.-!-Formerly EC 1.2.1.2. | Formate dehydrogenase H is a cytoplasmic enzyme that oxidizes formate without oxygen transfer, transferring electrons to a hydrogenase.-!-The two enzymes form the formate-hydrogen lyase complex.-!-The enzyme contains a selenocysteine residue.-!-Formerly EC 1.1.99.33 and EC 1.17.99.7. formate + NAD(+) = CO2 + NADH. | A + formate + H(+) = AH2 + CO2. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 344278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 729641 0 818947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1449718 0 1942082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAERIDVDETGK MGYG000001689_00148;MGYG000001338_00681;MGYG000004735_00336 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Belongs to the formate--tetrahydrofolate ligase family 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437433 0 0 0 0 0 0 0 -AAERNPEIAIQYK MGYG000002478_01152 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG2268@1|root,COG2268@2|Bacteria,4NIH3@976|Bacteroidetes,2FNXI@200643|Bacteroidia,4AP1M@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SPFH Band 7 PHB domain protein 1.0 yqiK 1.0 - 1.0 - 1.0 ko:K07192 1.0 ko04910,map04910 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03036,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Band_7,Flot 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Insulin signaling pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAERYAYVAK MGYG000003266_01415;MGYG000001642_00536 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CURX@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 alcohol dehydrogenase 1.0 adh1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAES(Deoxy[S](Ser->Ala)YFLLAEAK MGYG000001835_02184;MGYG000003363_01544 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 933154 0 0 0 0 0 0 0 0 0 0 388755 0 1599306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 679618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAESAAQAQNEK MGYG000001346_00694;MGYG000004899_00787 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0845@1|root,COG0845@2|Bacteria,4NECC@976|Bacteroidetes,2FMDD@200643|Bacteroidia,4ANZR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Auxiliary transport protein, membrane fusion protein (MFP) family protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01993 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 451645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 576770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 719594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAESGEVVEGDVTEFNK MGYG000002223_00230;MGYG000002040_01384;MGYG000002272_02217;MGYG000002610_00834;MGYG000000911_00719;MGYG000001300_00580;MGYG000000039_01115;MGYG000001255_00085;MGYG000002641_00839;MGYG000003291_01006;MGYG000000195_02259 domain d__Bacteria 1.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3WGII@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 IJM 1.0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Ribosome;Metabolic pathways;Biosynthesis of secondary metabolites;Terpenoid backbone biosynthesis 1.0 none 1.0 1133281 981503 843487 1650509 153449 850055 1062039 574584 1269197 798664 757990 857974 902825 864562 907175 1046437 1239665 2376809 1197932 1225454 567847 884278 2298259 1056745 820330 1138330 1063081 2042043 638542 1021454 932303 783260 1006886 1359841 731138 1424516 1067730 862096 2601591 2275980 2645193 2968473 1331590 2418993 3091436 1567728 3546819 782305 1792791 3082056 1943136 3526158 2440682 2528823 2972551 5294514 3930372 3035707 1806442 1847616 5766128 2468723 3557378 2909002 2619190 5173419 813615 2273347 2205361 1996524 2545211 2327766 1218593 2422388 2467001 2514752 580419 418582 504181 341737 581051 256864 879020 414503 596563 526190 706952 561735 312295 622194 648694 476938 171669 2991432 415188 378104 697391 398397 2994822 361465 461082 657677 370712 2888425 470992 533520 518792 333615 543439 550349 414601 619392 611380 574160 1077997 1616311 1727816 1718421 1384784 2054248 2362297 946434 1334438 1040929 1608033 2320348 1759961 1434138 929377 1582569 1261682 2733281 1642323 1743500 1731618 1965264 1957869 1725415 1433530 1254816 1035132 1981418 687595 1672438 2122358 1476013 1693983 1378461 544860 1320175 1212372 1796832 0 256528 403594 0 203022 0 0 448301 0 0 0 0 288242 0 0 257858 0 3904776 0 171365 0 200805 4321513 0 0 0 250677 5059401 0 0 284774 281024 503977 349781 216594 0 0 487692 -AAESGEVVEGDVTEFNKGGVVVNVK MGYG000002040_01384;MGYG000002272_02217;MGYG000001300_00580;MGYG000000039_01115;MGYG000001255_00085 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3WGII@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 IJM 1.0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Ribosome;Metabolic pathways;Biosynthesis of secondary metabolites;Terpenoid backbone biosynthesis 1.0 none 1.0 616943 843000 1182824 943840 0 780067 732978 0 692708 0 1049254 634881 0 879125 613454 692135 1156287 1553744 805744 704457 301897 878415 1469437 855169 711206 507710 715484 1934990 0 0 1095547 0 1182989 991825 0 0 645700 982347 562646 469219 620887 626703 0 659437 706077 0 721482 0 658470 635006 0 719241 840092 583938 1013912 771717 831747 547544 476839 845735 711094 488796 871384 626943 722832 876723 0 0 742180 0 517022 783775 0 0 630195 635949 0 355384 648377 451081 0 605095 325640 0 494617 0 374418 0 0 0 0 350396 696301 708115 417787 0 242828 308020 924714 289363 273505 372765 288809 926534 0 0 244982 0 320668 292624 0 0 310149 254688 523888 508595 1064335 532667 0 897173 768782 0 650974 0 666017 1143017 0 633979 592250 569209 574371 736362 749544 545059 1049528 773990 1608343 801483 701067 698942 659511 687192 0 0 713487 0 839574 891489 0 0 694098 730119 208610 0 263141 0 0 191956 0 0 228133 0 249693 0 0 0 273107 266434 300329 1078279 299833 224945 242339 0 740240 207406 255557 161358 224537 1011614 0 0 318945 0 254374 0 0 0 370541 308734 -AAESGLSKADAK MGYG000000243_01852 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia,4ARQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 988941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1022115 0 0 0 0 796642 0 0 627987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 126439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139439 0 0 0 0 184008 0 0 153780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121766 0 0 0 0 327619 0 0 327303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78369 0 0 0 0 508268 -AAESINLN(Deamidated)GTPAGK MGYG000002492_00017 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Phosphotransferase System 1.0 fruA 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 GGDEF,PTS_EIIA_2,PTS_EIIC,PTS_IIB,Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS);Metabolic pathways;Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 712718 0 0 0 0 0 0 0 0 0 541563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 630545 0 0 0 0 432210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAESINLNGTPAGK MGYG000002492_00017 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Phosphotransferase System 1.0 fruA 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 GGDEF,PTS_EIIA_2,PTS_EIIC,PTS_IIB,Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS);Metabolic pathways;Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348101 0 0 0 0 360710 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 716077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 914851 0 0 0 0 697326 0 0 1826955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306300 0 0 0 0 462224 0 0 0 0 0 0 0 0 0 0 0 0 373475 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564210 -AAESNPAIAIQYK MGYG000002717_01620;MGYG000004876_02300;MGYG000003312_01422;MGYG000000013_00587;MGYG000002561_00344;MGYG000000196_00432;MGYG000003701_03766;MGYG000001378_02290;MGYG000003351_02442;MGYG000004899_00490;MGYG000000243_00077;MGYG000002549_00282;MGYG000002470_01608;MGYG000000236_03206;MGYG000002281_04177;MGYG000000054_00015;MGYG000001345_01047 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2268@1|root,COG2268@2|Bacteria,4NIH3@976|Bacteroidetes,2FNXI@200643|Bacteroidia,4AP1M@815|Bacteroidaceae 0.9411764705882353 976|Bacteroidetes 1.0 S 1.0 SPFH Band 7 PHB domain protein 0.9411764705882353 yqiK 1.0 - 1.0 - 1.0 ko:K07192 1.0 ko04910,map04910 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03036,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Band_7,Flot 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Insulin signaling pathway 1.0 none 1.0 1634741 1643036 2034918 2078718 1775838 1727118 2186904 1846143 1631330 1765742 1570621 1505809 1743405 1757970 1870096 1950604 1802330 860689 1396836 1892371 1796097 1411470 921385 1787854 1975201 1959849 1570665 740577 1491763 1613989 1620034 1583394 2147354 2195498 1725127 1718492 1615981 2255345 1776095 0 0 2180296 0 0 1740955 1751426 1755671 2010001 0 1176789 0 1769006 1176333 1741540 1027863 0 1392576 1802709 1188088 2225773 1904393 0 1496274 1929526 2036685 0 0 1334832 0 1071338 2272265 1735079 1536352 1685261 1649286 0 901406 1468085 1747142 755239 1274990 1027252 999412 1353113 1392109 1343953 1075068 1504573 1593760 1144288 1470775 1862568 1327178 932451 1471411 1083843 823474 1595002 1118681 966058 769152 731846 851600 1362624 1056192 1271579 1254420 1040712 0 1582112 1605026 900758 1434871 1745418 646793 919797 733998 762279 805483 993877 705310 652196 684527 896314 1002869 611849 917817 691211 731738 1159024 729107 744185 714649 727540 754329 1236283 611797 1029301 729967 697985 827933 727958 1018179 688387 649948 715644 814770 615598 814685 832964 813183 609287 495754 542245 600680 506865 312071 746001 1078741 424087 232929 582803 630173 397461 918252 413060 385228 754785 425286 945081 225081 657650 583028 553821 738925 699376 551678 344823 467680 865313 429144 823917 622323 842619 515855 478585 0 333707 819938 355761 -AAESRPAPFLIHQESNVIVR MGYG000002494_01208 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,3WWD0@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs 1.0 rne 1.0 GO:0000287,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008312,GO:0008995,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0017151,GO:0019222,GO:0019439,GO:0019899,GO:0022607,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043462,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048519,GO:0050789,GO:0050790,GO:0051095,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902280 1.0 3.1.26.12 1.0 ko:K08300 1.0 ko03018,map03018 1.0 M00394 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PNPase_C,RNase_E_G,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribonuclease E. RNase E. RNase E is a bacterial ribonuclease that plays a role in the processing of ribosomal RNA (9S to 5S rRNA), the chemical degradation of bulk cellular RNA, the decay of specific regulatory, messenger and structural RNAs and the control of plasmid DNA replication.-!-The enzyme binds to monophosphorylated 5' ends of substrates but exhibits sequential cleavages in the 3' to 5' direction.-!-2'-O-methyl nucleotide substitutions at RNase E binding sites do not prevent binding but do prevent cleavage of non-modified target sequences 5' to that locus.-!-In Escherichia coli, the enzyme is found in the RNA degradosome.-!-The C-terminal half of the protein contains binding sites for the three other major degradosomal components, the DEAD-box RNA helicase Rh1B, EC 4.1.1.11 and EC 2.7.7.8.-!-Formerly EC 3.1.26.n1. Endonucleolytic cleavage of single-stranded RNA in A- and U-rich regions. 1.0 1.0 1.0 1.0 RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 689489 0 388571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAESVLM(Oxidation)EIVR MGYG000001521_00864;MGYG000002154_00941;MGYG000004833_01068;MGYG000001563_00272;MGYG000001541_01134;MGYG000000185_01922;MGYG000001506_00184 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 E 1.0 Beta-eliminating lyase 1.0 tnaA 1.0 - 1.0 4.1.99.1 1.0 ko:K01667 1.0 ko00380,map00380 1.0 - 1.0 R00673 1.0 RC00209,RC00355 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Beta_elim_lyase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 tryptophanase. TNase. The enzyme cleaves a carbon-carbon bond, releasing indole and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-Also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine and other 3-substituted amino acids. H2O + L-tryptophan = indole + NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 Tryptophan metabolism 1.0 none 1.0 0 373614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1080395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAESVLMEIVK(Lys->Arg) MGYG000002057_00764;MGYG000002944_00213;MGYG000002993_00539;MGYG000002036_00786;MGYG000001632_01270 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia 0.8 186801|Clostridia 1.0 E 1.0 Beta-eliminating lyase 1.0 tnaA 1.0 - 1.0 4.1.99.1 1.0 ko:K01667 1.0 ko00380,map00380 1.0 - 1.0 R00673 1.0 RC00209,RC00355 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Beta_elim_lyase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 tryptophanase. TNase. The enzyme cleaves a carbon-carbon bond, releasing indole and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-Also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine and other 3-substituted amino acids. H2O + L-tryptophan = indole + NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 Tryptophan metabolism 1.0 none 1.0 1374335 0 0 0 424992 967949 0 0 0 0 1162691 2111576 0 598804 262262 0 0 0 0 0 0 1533283 0 0 699599 0 0 0 0 1037316 0 0 550975 692858 0 0 681867 656428 0 0 2647895 5195959 4082015 0 0 364227 2439131 0 3341424 0 0 0 3696661 0 0 0 4592162 0 0 3756712 0 0 3450334 0 5157660 0 0 0 0 0 1987684 3232361 0 0 2906338 1836045 2373035 0 0 0 0 0 0 0 1625900 2306147 0 2282745 0 1918735 0 0 0 0 2447194 0 0 0 0 0 1883046 2188151 2454437 0 0 0 0 0 2092173 0 0 0 2012889 1488038 984363 0 818224 1022448 885714 903620 686516 0 753272 1014916 937859 679922 0 1154196 697567 0 0 0 758337 1093869 0 1089809 0 1122736 803205 612888 967474 0 0 949605 0 0 0 426603 0 0 626236 920669 2239137 0 0 3513530 2292667 2115049 2874202 2967347 2178346 3407981 2554097 2094463 0 3113340 2608986 0 0 0 3066940 0 0 2422682 0 1913899 2914194 2524435 0 0 0 3365522 0 0 0 3487848 0 0 3122540 2826824 -AAESVLMEIVKK MGYG000002057_00764;MGYG000003753_00223;MGYG000002944_00213;MGYG000002993_00539;MGYG000003770_02347;MGYG000001632_01270 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 E 1.0 Beta-eliminating lyase 1.0 tnaA 1.0 - 1.0 4.1.99.1 1.0 ko:K01667 1.0 ko00380,map00380 1.0 - 1.0 R00673 1.0 RC00209,RC00355 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Beta_elim_lyase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 tryptophanase. TNase. The enzyme cleaves a carbon-carbon bond, releasing indole and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-Also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine and other 3-substituted amino acids. H2O + L-tryptophan = indole + NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 Tryptophan metabolism 1.0 none 1.0 902908 0 1037842 0 689798 936192 1239822 1378185 1266948 0 0 598447 0 0 1017041 0 1103028 711464 0 705942 597168 849425 714768 879559 784626 1135692 0 871197 1249702 790695 1041988 0 952024 0 0 0 1015491 793783 44999 0 72504 0 172042 92011 84152 73746 65518 0 0 54033 0 0 9913914 0 94748 121448 0 132181 67962 127569 0 67807 62050 88486 0 97990 159523 59450 0 0 52708 0 0 0 120761 89132 408646 0 166534 0 257763 377690 338620 430588 356899 0 0 501048 0 0 378264 0 400843 671132 0 354864 332058 399609 708843 401426 282905 198002 0 506535 401384 391996 463610 0 303203 0 0 0 412471 312947 565778 0 672860 0 623201 806968 944346 751336 653955 0 0 461605 0 0 452718 0 594933 834438 0 753412 1736083 664064 651564 676963 1651207 760866 0 741093 568459 520774 677151 0 648754 0 0 0 575690 630246 0 0 0 0 120091 0 563329 0 0 0 0 195745 0 0 0 0 0 150442 0 0 0 0 123240 180983 0 0 0 199517 833635 0 0 0 301677 0 0 0 0 0 -AAESVLMEIVR MGYG000001521_00864;MGYG000002154_00941;MGYG000004833_01068;MGYG000001563_00272;MGYG000001541_01134;MGYG000000185_01922;MGYG000001506_00184 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 E 1.0 Beta-eliminating lyase 1.0 tnaA 1.0 - 1.0 4.1.99.1 1.0 ko:K01667 1.0 ko00380,map00380 1.0 - 1.0 R00673 1.0 RC00209,RC00355 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Beta_elim_lyase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 tryptophanase. TNase. The enzyme cleaves a carbon-carbon bond, releasing indole and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-Also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine and other 3-substituted amino acids. H2O + L-tryptophan = indole + NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 Tryptophan metabolism 1.0 none 1.0 0 0 0 0 0 0 280639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1076564 0 0 0 3805436 3613155 349834 0 0 4180664 5401631 5584461 0 0 0 3318919 0 0 0 2448969 3852143 0 0 4649194 3223353 4672603 0 4505248 0 3487552 0 0 0 0 5128522 0 0 0 3455969 3402138 0 0 0 3227608 1615720 2062028 0 1894847 1776461 2177076 0 0 0 0 0 0 0 2338907 0 662559 0 2438343 0 2431718 0 0 0 0 0 1523650 2060946 0 0 0 0 0 0 1515742 0 0 0 0 0 0 0 0 0 672157 0 0 0 0 0 0 0 0 0 407295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 930904 0 0 0 0 0 0 2481941 2431511 0 0 0 0 0 0 0 0 0 0 0 0 0 2541929 0 0 2521811 0 0 1634964 0 0 0 0 0 4028910 0 0 0 3448065 0 0 2950625 0 0 -AAESVLVC(Carbamidomethyl)VSGR MGYG000002274_01087;MGYG000002641_01949;MGYG000002040_00027;MGYG000004679_00212;MGYG000002545_01805;MGYG000001300_02656;MGYG000003291_01552 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 translation elongation 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 597010 0 613358 723313 0 676679 0 0 504974 0 694613 569106 0 0 500818 0 0 1171428 0 867054 0 483166 999946 645448 541648 659280 0 1252743 0 0 0 0 1345775 464618 0 0 557751 748878 1230136 0 748882 1278772 0 773278 0 0 1030716 0 1190165 983202 0 0 1275671 0 0 1370162 0 1230606 0 852046 1148520 891486 1392901 1093102 0 1294090 0 0 0 0 642117 873631 0 0 853585 682654 398384 0 5815261 764909 0 590139 0 0 644988 0 744319 763720 0 0 368730 0 0 1779143 0 393971 0 542679 1859388 536895 460870 560460 0 1873946 0 0 0 0 3323243 603372 0 0 514650 1723432 604378 0 712099 656125 0 595616 0 0 627494 0 568782 822769 0 0 628004 0 0 519274 0 871929 0 497004 1034602 518415 567303 831542 0 655672 0 0 0 0 528969 499263 0 0 661881 420506 0 0 573673 525010 0 769242 0 0 270714 0 471522 809100 0 0 462035 0 0 1949922 0 1079745 0 418770 2603817 532579 562089 987642 0 2734375 0 0 0 0 361024 0 0 0 843282 733344 -AAESYFLLAEAK MGYG000001835_02184;MGYG000003363_01544 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629117 0 0 0 0 0 0 0 0 0 1027335 0 0 599584 545659 0 753868 0 0 0 0 0 0 555028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 963340 0 0 0 0 709990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAETAMDVTTK MGYG000000077_02467;MGYG000000262_02234 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 261791 0 0 0 299753 0 0 0 514133 0 0 314347 0 521487 345654 0 0 486655 405891 0 584532 0 0 525337 0 228665 0 0 0 0 0 0 250605 453302 0 400553 0 544875 1118767 0 0 0 1117228 373227 0 0 0 0 0 442980 0 0 385323 914380 0 1382656 592480 0 1157221 0 287319 277670 271093 646096 0 0 640281 0 0 0 0 0 0 0 0 1135150 733705 0 0 0 641947 249575 0 0 1141239 0 0 687507 0 1365034 668351 453929 0 1452287 1126833 0 1105849 0 343462 1310749 905782 1373588 0 0 622934 0 0 0 1174984 1219089 0 935633 0 1197739 1630549 0 0 0 1970845 1698118 0 0 2012192 0 0 1391508 0 933924 2387730 1805236 0 904377 1685245 0 1566305 0 1757748 802725 375591 1211308 0 0 1305980 0 0 0 392400 1072438 0 682634 0 0 0 0 0 0 312230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167555 0 -AAETAVAGR MGYG000002517_00489 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 lipid kinase, YegS Rv2252 BmrU family 1.0 dagK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DAGK_cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267514 0 0 0 0 365590 0 0 0 0 328341 425807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54496 0 0 0 0 0 0 816350 727873 0 0 0 0 0 489352 0 0 0 0 687824 0 0 0 0 753000 481620 0 0 0 0 0 0 0 0 463966 0 631061 0 1029359 0 0 0 0 0 0 883020 758866 0 0 0 0 0 770944 0 0 0 0 1153602 0 0 0 0 691187 660564 0 0 0 0 0 0 0 0 978063 0 1072909 0 694940 0 0 0 0 0 0 523139 808036 0 0 0 0 0 818805 0 0 0 0 381289 0 0 0 0 1265355 1453250 0 0 0 0 0 0 0 0 1162192 0 1500135 0 -AAETDIIPR MGYG000001338_01246 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3XZKB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1158628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247967 0 0 0 0 0 0 -AAETLNNLR MGYG000002517_02001 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia 1.0 186801|Clostridia 1.0 NT 1.0 methyl-accepting chemotaxis protein 1.0 - 1.0 - 1.0 - 1.0 ko:K03406 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 MCPsignal,sCache_3_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 586769 0 243955 490450 300618 0 0 0 493690 476689 0 320482 0 0 0 0 0 0 596138 500604 0 0 0 0 355233 442416 349919 0 0 148590 0 0 532698 553331 346630 473646 411124 0 154453 0 451117 0 400403 0 0 0 0 383240 0 796721 0 0 144803 0 0 0 400422 0 0 0 0 0 0 0 0 0 0 431138 0 0 711387 0 0 0 0 479011 749486 0 287747 0 0 0 0 0 0 338823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343015 0 0 0 0 270519 0 0 0 0 577872 0 373973 204926 1830347 0 206342 2402871 2151464 0 0 1623944 1902477 3871329 0 1671777 0 0 2032765 0 0 0 1951968 2050676 0 0 0 0 1717023 1932813 1547383 0 0 2180826 0 0 507839 1458612 1434348 1616505 2595754 0 617689 0 861701 0 907986 0 0 557628 592676 1049952 0 504368 0 0 1080679 0 0 0 715252 868988 0 0 0 0 1101854 655268 486014 0 0 708287 0 0 799411 1074018 659316 1093889 458281 688415 -AAETLPDGVQIVK MGYG000003352_01343 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella|s__Parasutterella sp900766055|m__MGYG000003352 1.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria 1.0 28216|Betaproteobacteria 1.0 O 1.0 Belongs to the thioredoxin family 1.0 trxA 1.0 - 1.0 - 1.0 ko:K03671 1.0 ko04621,ko05418,map04621,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 Thioredoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Fluid shear stress and atherosclerosis;NOD-like receptor signaling pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2141982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAETLVATHPDLAAR MGYG000001300_00314 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1305@1|root,COG1305@2|Bacteria,1TT33@1239|Firmicutes,24B27@186801|Clostridia,3WPMU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 Transglutaminase-like superfamily 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Transglut_core 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 253041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 712633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAETMAGLSGTR MGYG000001567_01031;MGYG000003096_00465;MGYG000002919_01788;MGYG000001642_00466;MGYG000003266_01691 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0549@1|root,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria,4CUT3@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Belongs to the carbamate kinase family 1.0 arcC 1.0 - 1.0 2.7.2.2 1.0 ko:K00926 1.0 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 1.0 - 1.0 R00150,R01395 1.0 RC00002,RC00043,RC02803,RC02804 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 AA_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 carbamate kinase. - The enzyme catalyzes the reversible conversion of carbamoyl phosphate and ADP to ATP and carbamate, which hydrolyzes to ammonia and hydrogen carbonate.-!-The physiological role of the enzyme is to generate ATP. ATP + hydrogencarbonate + NH4(+) = ADP + carbamoyl phosphate + H(+) + H2O. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Purine metabolism 1.0 none 1.0 951269 0 0 0 0 668569 0 0 0 0 0 0 0 0 1199272 0 0 0 0 0 0 656023 0 348787 1439809 637287 0 0 0 0 0 0 0 0 0 0 698065 0 1429555 0 0 0 0 1216945 0 0 0 0 0 0 0 0 850729 0 0 0 0 0 0 333440 0 1680921 1415790 1116547 0 0 0 0 0 0 0 0 0 0 1535949 0 1044977 0 0 0 0 385537 0 0 0 0 0 0 0 0 981001 0 0 0 0 0 0 1030923 0 0 862859 689490 0 0 0 0 0 0 0 0 0 0 817762 0 221208 0 0 0 0 377552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546618 0 662959 0 143825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 566024 0 0 0 0 0 0 0 0 0 622428 348654 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVA(Ala->Thr)LVGTEK MGYG000000212_01004;MGYG000003012_02042;MGYG000004733_01677;MGYG000000301_01355;MGYG000002298_00042;MGYG000004785_00406;MGYG000000806_00431;MGYG000002298_02777;MGYG000000142_01603;MGYG000000031_02920;MGYG000000171_01277 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3471829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3478255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3107735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563621 0 0 0 0 0 0 0 0 -AAEVAAQAAK MGYG000002445_00877 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp003024715|m__MGYG000002445 1.0 COG1788@1|root,COG1788@2|Bacteria,1UYH2@1239|Firmicutes,24CPB@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit 1.0 gctA 1.0 - 1.0 2.8.3.12 1.0 ko:K01039 1.0 ko00643,ko00650,ko01120,map00643,map00650,map01120 1.0 - 1.0 R04000,R05509 1.0 RC00012,RC00131,RC00137 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconate CoA-transferase. - Glutarate, (R)-2-hydroxyglutarate, propenoate and propanoate, but not (Z)-glutaconate, can also act as acceptors. acetyl-CoA + trans-glutaconate = (2E)-glutaconyl-CoA + acetate. 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Styrene degradation 1.0 none 1.0 0 0 0 0 903652 751117 0 1278128 0 1535449 1527906 0 0 0 1862913 1051760 0 0 0 0 0 1318144 0 1031690 2168262 0 1194246 0 0 1214837 0 0 0 1640435 0 0 0 0 0 0 0 0 552591 767633 0 618511 0 0 642053 0 0 0 738754 604372 0 0 0 0 0 801794 0 1014743 676659 0 832161 0 0 651282 0 0 0 598056 0 0 0 0 0 0 0 0 630405 1001100 0 1050181 0 1437056 930402 0 0 0 1609018 1105625 0 0 0 0 0 1246666 0 1077018 1229828 0 1427044 0 0 851673 0 0 0 1998143 0 0 0 0 0 0 0 0 707201 667877 0 503519 0 506296 886666 0 0 0 397329 588021 0 0 0 0 0 704896 0 959916 503708 0 469923 0 0 422394 0 0 0 483551 0 0 0 0 0 0 0 0 396414 472201 0 514770 0 974438 1183085 0 0 0 842589 716597 0 0 0 0 0 582541 0 1047288 1218161 0 1023628 0 0 401538 0 0 0 1002932 0 0 0 0 -AAEVAEAIR MGYG000000090_02779 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter sp014287875|m__MGYG000000090 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,2690F@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVAGKPYEDLK MGYG000000233_01457 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,21XHV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 620994 0 145745 559550 310097 0 591736 777446 551178 505297 0 0 0 357460 0 0 143318 0 554874 565839 0 0 0 0 0 246497 172166 0 650608 0 0 0 248435 704718 0 541389 318098 288469 1100824 0 675218 1869235 854095 0 1150814 1563220 1148702 1240777 0 0 0 1084090 0 0 946121 0 869405 940681 0 0 0 0 0 968473 1015977 0 1188231 0 0 0 1053177 1332449 0 958599 792265 935711 388710 0 111354 546364 323682 0 539149 627842 435974 573444 0 0 0 260025 0 0 411420 0 658787 184113 0 0 0 0 0 564005 548731 0 507607 0 0 0 243262 644198 0 319977 471354 329623 792559 0 703333 922145 687502 0 1032911 976614 284144 878916 0 0 0 504828 0 0 439026 0 925379 241010 0 0 0 0 0 895785 276170 0 406898 0 0 0 773447 317609 0 887476 339109 459704 152477 0 240572 355151 178545 0 208328 170550 302134 209165 0 0 0 182192 0 0 71823 0 277351 0 0 0 0 0 0 471224 110811 0 339678 0 0 0 262805 216030 0 134517 279614 200748 -AAEVALVGTEK MGYG000000212_01004;MGYG000003012_02042;MGYG000004733_01677;MGYG000000301_01355;MGYG000002298_00042;MGYG000004785_00406;MGYG000000806_00431;MGYG000002298_02777;MGYG000000142_01603;MGYG000000031_02920;MGYG000000171_01277 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 4965577 4673807 0 5572025 7250017 2474741 5449012 3544679 4904576 7364764 5780755 5241695 1782775 5691817 5234296 6427989 8014938 4422783 0 4705103 5512793 5482812 3883600 5406625 3283691 3671135 6334441 6701846 4597286 4084830 4500830 4659082 1197142 4781061 1288255 3416466 5156185 2958730 3989244 1814000 2491078 2462508 1758500 2758201 2957781 2316019 1324405 2578196 1642320 2275880 2064664 1716754 1532077 2772076 4894347 1554653 2168043 1080342 1602223 2450006 3091097 1460326 2451693 2865219 3506489 6932956 1950671 4929972 2085506 1973389 1717993 3098400 3116772 2577965 2890937 0 7761812 6355490 5477483 3527521 6193099 0 7671511 0 0 0 4930829 5442537 6745014 0 0 10423074 2855428 9958272 7399290 7776248 11180232 3690174 5628776 8837740 7656108 9499662 3174303 6257498 7921456 7035192 7521783 7651571 0 5042005 0 7332558 0 0 5910876 3288017 3088780 3995864 3324421 3926606 2667540 3257060 4442070 2694055 4083803 4129693 0 2769046 3433370 6002239 3554869 2744132 3965964 2902447 4228500 2755095 4916099 2455846 2270116 0 4397192 16247287 4371670 5344667 3741243 3905691 2088372 2507778 2821249 2797242 3935262 16962839 16446246 18862591 23998688 5812402 13394008 23328272 16372418 13382984 21910766 19455688 16892576 11647721 22526596 17468010 11204927 17588432 3163582 14192100 9598468 20960268 15506876 5158908 12900593 12890410 20729891 17839827 5728977 26013575 9096237 14647186 24857181 26338298 15645271 10721664 15486298 10772792 13811622 -AAEVAYTGTQEPVKEMQK MGYG000001345_00049 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides xylanisolvens|m__MGYG000001345 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1909217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVC(Carbamidomethyl)LELL(Xle->Met)TK MGYG000000074_02401 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 - 1.0 ko:K03522 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339170 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 784677 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVDEDERFPR MGYG000000223_02387 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,3VQ5H@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVDEEERFPIETVK MGYG000002485_00623 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG1960@1|root,COG1960@2|Bacteria,378TZ@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Acyl-CoA dehydrogenase, N-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1076367 0 0 1172422 0 0 0 0 0 0 0 0 0 1374074 0 0 0 0 0 987615 0 1137895 0 0 0 0 0 0 0 0 1128965 0 0 0 0 581625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400724 0 81145 0 0 0 0 0 0 0 0 0 0 0 0 0 327766 -AAEVDEEERFPIETVKK MGYG000002485_00623 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG1960@1|root,COG1960@2|Bacteria,378TZ@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Acyl-CoA dehydrogenase, N-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1033748 0 0 2018970 1288112 0 0 2242423 1495548 0 1080809 0 0 1607752 1435029 0 0 0 0 1557550 0 1716657 0 0 306001 0 0 0 0 0 1118980 0 0 0 0 1242543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVDIIPR MGYG000001319_00230;MGYG000000018_00286;MGYG000000171_00630 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,4BY3S@830|Butyrivibrio 0.3333333333333333 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 646666 0 0 0 282287 0 0 0 258635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1233980 529519 0 0 0 0 0 0 0 0 1033197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 931033 0 0 3546228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVDLIPR MGYG000002580_00753;MGYG000001698_03459;MGYG000000251_01241;MGYG000000271_00461;MGYG000000171_00630;MGYG000000404_00591;MGYG000000002_01946;MGYG000002517_01665;MGYG000002279_00585;MGYG000001319_00230;MGYG000000217_00285;MGYG000000038_02213;MGYG000002492_01767 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia 0.3076923076923077 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.8461538461538461 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 202530 0 0 89988 176760 0 159298 595335 303918 196194 140919 0 0 340309 0 132058 185172 612292 649032 400984 0 0 180449 0 496599 217596 229731 1700152 480065 218097 0 0 0 0 139643 232048 259030 0 238507 0 164384 114195 190384 0 158345 199155 169285 182325 0 0 0 119148 0 191738 147243 1046200 297066 90754 0 0 395120 0 120359 185871 166445 685756 577037 239312 0 0 321179 0 119508 249459 97236 104697 533553 0 1428391 619359 493625 0 411367 434110 666812 555536 609247 0 0 0 563399 645022 352519 377488 0 692975 0 0 481553 0 759551 591289 572800 494541 420923 620868 0 0 966173 0 612553 439582 858798 1138347 1811970 0 585561 2211103 907110 0 1005321 2182542 2082704 1027359 734939 0 0 2277926 2165261 950527 1853060 789415 1991609 1976549 0 0 508335 0 1666745 1588823 2094255 986006 2054824 1759467 0 0 503019 0 1866244 1704372 2359985 600296 350884 0 238945 325529 302200 0 184697 170321 158346 225711 202528 0 0 302435 266197 188125 291928 0 311557 0 0 0 206883 0 238445 180670 269822 219821 233766 149380 0 0 296027 0 221287 348642 268228 123375 -AAEVDLLPR MGYG000004891_01493;MGYG000001319_00230;MGYG000000018_00286;MGYG000000171_00630;MGYG000002141_01157;MGYG000000252_00324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3XZKB@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.8333333333333334 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2388477 0 0 0 0 1261983 0 527182 0 0 1606871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053147 0 591105 0 0 416074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1949654 0 0 0 0 3288543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVFGR MGYG000002515_04339;MGYG000002506_04112;MGYG000002323_00588 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3ZJCJ@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 F 1.0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 deoA 1.0 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 1.0 2.4.2.4 1.0 ko:K00758 1.0 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 1.0 - 1.0 R01570,R02484,R08222,R08230 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 1.0 Glycos_trans_3N,Glycos_transf_3,PYNP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thymidine phosphorylase. pyrimidine phosphorylase. In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.-!-Formerly EC 2.4.2.23. phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine. 1.0 1.0 1.0 1.0 Metabolic pathways;Drug metabolism - other enzymes;Bladder cancer;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 1923118 0 2250211 0 2169249 0 0 0 0 2444534 0 2100939 0 0 0 2306853 1816615 0 1402331 2096604 0 1547737 0 1620540 0 0 1836816 0 1984750 1646436 1421493 0 0 0 0 0 0 0 0 0 2018762 0 1360425 0 0 0 0 931025 0 4422005 0 0 0 0 0 0 0 1248810 0 2285269 0 0 0 0 1249862 0 1925241 1403668 1905856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3899399 0 0 0 0 4933918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1478790 0 0 0 0 0 0 0 0 0 0 0 0 0 2668579 2303422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 515988 0 0 0 0 0 0 0 475457 0 0 1176164 0 119509 92181 0 0 0 -AAEVFVLC(Carbamidomethyl)VK MGYG000001338_03280 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,3WGVJ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 EK 1.0 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Aminotran_MocR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 1405150 809428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1059249 506170 0 0 0 0 0 0 855112 416117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1459513 498793 405383 0 0 0 0 437500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 684801 0 0 0 0 0 0 0 0 1614891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756855 0 0 0 0 0 0 1997623 962935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 745724 1481165 1182986 0 0 0 0 0 -AAEVGILPR MGYG000003291_01172;MGYG000001300_01096 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 482441 443945 0 400303 0 0 0 0 0 0 0 0 0 126519 364016 0 1028946 904955 0 356756 0 245229 333228 0 0 0 0 0 194070 0 292574 0 0 0 0 538715 0 253117 262500 0 131215 0 0 0 0 0 0 0 0 0 0 262673 452847 0 172950 0 0 0 0 0 0 0 0 0 0 142983 0 0 0 0 0 0 0 0 0 209419 338292 255954 317120 220488 0 0 0 0 0 0 0 0 0 181171 0 0 0 0 0 0 0 0 292406 0 0 0 0 193977 315248 0 0 0 0 0 0 365916 0 1576233 2161321 1256105 1608555 2193768 0 0 0 0 0 0 0 0 0 1537064 1508168 0 2883197 1616809 0 2111028 0 2052474 1090628 0 0 0 0 1963114 2377036 0 2140609 0 0 0 0 2375775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVGLLPR MGYG000003494_02094;MGYG000000022_00767;MGYG000001300_01096;MGYG000000573_01219;MGYG000000084_01970 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2173462 0 0 1346491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2097130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVIDMR MGYG000001302.1_01603 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,2FNQK@200643|Bacteroidia,22V6X@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate 1.0 hutU 1.0 - 1.0 4.2.1.49 1.0 ko:K01712 1.0 ko00340,ko01100,map00340,map01100 1.0 M00045 1.0 R02914 1.0 RC00804 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Urocanase,Urocanase_C,Urocanase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 urocanate hydratase. urocanase. - 4-imidazolone-5-propanoate = H2O + trans-urocanate. 1.0 1.0 1.0 1.0 Metabolic pathways;Histidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1230269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVIEFNPALEEN(Deamidated)NR MGYG000002492_00661 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025734 0 0 0 0 618761 0 0 0 0 1147481 0 0 0 0 491963 0 0 0 0 342910 0 0 701514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378698 0 0 0 0 935012 0 0 0 0 662468 0 0 491565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVIEFNPALEENNR MGYG000002492_00661 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 591732 0 427193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136849 0 353907 0 0 0 0 0 0 0 0 745604 0 347860 0 0 0 1095432 0 2020442 1366740 2845531 834659 1569538 989461 908343 880362 2235879 1043667 1599953 1050983 902111 1234591 572575 14648268 832128 1300983 840840 599436 6501421 939252 1130427 1033806 1110338 10098925 1045264 797615 1872009 1457424 2302101 1231573 1061686 1266979 991236 2679786 2743425 0 10443857 2145274 3796491 2158993 2591042 2540302 2195332 2059211 3560183 3639866 3547755 2386183 2806518 5183079 2645449 2239985 1977452 2043694 2138106 2641524 4023427 1979866 2344771 3208003 2646761 6784273 1718863 2999099 3367815 2078327 12172003 2787255 2843567 2154728 2693624 13071759 0 0 95420 0 399170 0 0 0 0 0 301534 422746 99737 0 0 268687 0 0 0 0 0 0 0 318031 0 0 0 0 0 195127 359807 0 0 0 0 0 0 0 0 0 1113103 376311 0 0 395956 268454 259687 92467 568138 0 258820 0 756131 732897 358672 322300 95420 0 563739 0 496465 341671 356471 71216 269225 406288 0 304976 0 276680 504584 508437 427204 0 557883 300586 -AAEVIEFNPALEENNRYVEIMDIVK MGYG000002492_00661 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVIGK MGYG000002105_00879 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__SFJ001|s__SFJ001 sp004555865|m__MGYG000002105 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2350727 0 0 0 0 0 0 0 2283497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVLQGK MGYG000002517_01687;MGYG000000002_01851 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,25V1D@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 759914 0 0 783427 0 0 0 601524 699652 0 0 0 0 0 584142 0 491610 0 0 0 0 0 0 0 0 589908 0 0 0 682796 0 0 0 0 0 0 863835 0 618843 0 0 1298346 0 0 0 0 1081590 0 0 0 0 0 841260 0 914577 0 0 0 0 0 0 0 0 791003 0 0 0 996381 0 0 0 0 0 0 1140767 0 513952 0 0 352689 0 0 0 962786 1236193 0 0 0 0 0 519258 0 729371 0 0 0 0 0 0 0 0 397430 0 0 0 1031591 0 0 0 0 0 0 0 0 1680523 0 0 2285862 0 0 0 1307715 1357459 0 0 0 0 0 1843261 0 1483825 0 0 0 0 0 0 0 0 995968 0 0 0 1780367 0 0 0 0 0 0 2189658 0 0 0 0 340681 0 0 0 771177 545178 0 0 0 0 0 0 0 671165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802473 0 -AAEVPEAIR MGYG000004475_01155;MGYG000004276_01056;MGYG000001365_00975;MGYG000003819_01175;MGYG000004784_00619;MGYG000002057_00250;MGYG000002926_00519;MGYG000004831_00863;MGYG000002715_01105;MGYG000000099_02384;MGYG000004769_00455 domain d__Bacteria 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,2N6AV@216572|Oscillospiraceae 0.45454545454545453 186801|Clostridia 0.6363636363636364 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 0.8181818181818182 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 2314071 0 1872727 0 2435920 2336545 2831360 2372794 2331196 2193823 0 2027647 0 2490382 2064982 0 1921510 2135148 0 2770010 2390315 2263126 1878532 2863092 0 2413305 0 2268067 0 0 2574372 2678377 2120309 2722687 2547904 2226333 2776147 2428811 1948051 0 2189412 0 1867517 2132057 1840156 2754128 2363116 2409254 0 1872543 0 2374448 2307360 0 1993071 1018856 0 1784575 2032423 1589765 1038051 1402851 0 2255118 0 963010 0 0 1510553 2377653 2365175 2280571 2654931 2494023 2536644 1828524 2043691 0 2853393 0 2583771 2609796 2436751 2182327 1867102 2508581 0 255642 0 2383615 1705071 0 2234049 1525724 0 1771216 2074386 2379344 1361770 2540832 0 1798552 0 1222004 0 0 2478193 2008271 2141633 2468740 2290274 2197655 1769342 2198328 2446098 0 2956831 0 2221864 3273954 2946285 3473948 2514128 2637570 0 2100675 0 2254412 2432573 0 2192340 3136796 0 2119840 2022689 2607500 2495332 2880355 0 2447562 0 2851856 0 0 3139388 2602472 3052669 3057023 3370468 2706335 2420339 2889235 2141146 0 2154764 0 2154094 2413526 1844416 2712041 2282861 2749236 0 1894435 0 2250452 1994682 0 2101311 1715749 0 2004733 1598800 2581381 1644214 2070616 0 3342147 0 1766245 0 0 2685088 2477337 1765692 2081944 2222866 1905444 1840690 2306772 -AAEVPEAIRK MGYG000003819_01175;MGYG000004784_00619;MGYG000000591_02137;MGYG000004736_00682;MGYG000004769_00455;MGYG000002777_00372;MGYG000004276_01056;MGYG000002659_00440;MGYG000003770_01010;MGYG000004196_00621;MGYG000001617_01231;MGYG000002926_00519;MGYG000000099_02384;MGYG000002715_01105;MGYG000001444_01653;MGYG000001500_00899;MGYG000001365_00975;MGYG000001367_00366;MGYG000004475_01155;MGYG000001356_01784;MGYG000002882_01847;MGYG000002953_00608;MGYG000003869_00064;MGYG000002057_00250;MGYG000004831_00863 domain d__Bacteria 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,2690F@186813|unclassified Clostridiales 0.28 186801|Clostridia 0.6 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 0.84 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 2299130 1628571 1726768 1764404 1412756 2172535 2361524 2218866 2235670 1919281 1560518 1437089 1421968 2285777 2055853 1645499 1425180 1425933 1614878 2011353 2374303 1684280 1278276 2339590 1899108 2148882 2010509 1062642 894662 1634799 1657005 1523651 1679650 2425301 2001292 1975558 2242870 1605973 1950088 1260483 1558389 1428474 1482966 1334267 1323250 1991671 1854024 1773013 1569019 1242492 1330573 1668492 1813515 1194654 1627289 396980 1480138 1492769 1515164 1346306 436853 1001686 1558760 1493488 1610853 513516 1614124 1551952 1119431 1162731 1573120 1737026 1194035 1777496 1607892 1436129 2159731 2209248 2851158 2547250 2109685 2160424 2729052 3063376 2793291 2651917 2254388 1691119 1861122 2689467 2836449 1904519 2686039 1156746 2434541 2697376 2664971 2058516 1035638 2561427 2414942 2415509 2328351 1107020 2572086 2259665 2118857 1891951 1843589 2445903 1621459 2567110 2664915 2054005 2167337 2050535 2329874 1683033 1994033 2234285 2127917 2275289 1915825 2554911 1685253 1802815 1658283 2116813 2162774 1595930 2089558 1725312 1836794 1975294 1527415 1659753 1210031 2031179 1796831 2052719 1775986 1508096 2738281 1811241 1867421 2148380 2562066 2582722 2854912 2781557 2506311 2699911 1429438 1220748 1478255 0 1603286 1865009 1754941 1669726 1561791 1406875 1275062 1255462 1286500 842009 1429347 1345102 1480687 1416444 1219450 1389004 1174113 1732264 1072989 1322380 1596446 1967663 1189073 1084283 1029065 1219070 1364458 1273190 1304563 1369335 1218721 1912748 1483924 667291 -AAEVQDGKITVN(Deamidated)GK MGYG000002492_00430 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,25UXG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 201427 0 0 0 0 229159 128436 103107 0 0 342183 0 73984 0 139289 0 0 0 0 0 0 0 185447 0 0 0 0 97750 0 333816 0 0 0 0 0 0 336332 0 1281361 0 0 0 0 422196 1330203 304024 871070 0 317620 412808 281446 0 155905 0 0 0 0 0 0 0 465380 0 0 0 433619 427971 603966 479422 0 0 0 692406 0 0 774097 0 828989 0 0 0 0 911920 977559 1324582 1851094 0 756467 1286478 883763 0 785425 0 0 0 0 0 0 0 962220 0 0 0 932816 956833 572736 1008293 0 0 0 557046 0 0 228007 0 242941 0 0 0 0 206761 303627 336890 0 0 243455 287783 261155 0 260887 0 0 0 0 0 0 0 258804 0 0 0 0 0 176089 517723 0 0 0 173601 0 0 0 0 207285 0 0 0 0 242800 0 0 0 0 292490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309531 0 0 0 0 0 0 0 -AAEVQDGKITVN(Deamidated)GKDYVVR MGYG000002492_00430 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,25UXG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 347903 0 0 0 0 0 0 0 0 142744 221128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 137651 0 0 0 0 0 0 0 0 687639 0 0 0 191784 0 0 0 0 0 168037 0 0 0 0 0 304481 0 0 0 93619 336177 0 0 292932 0 0 0 0 1578329 0 0 0 875747 0 1163476 0 0 1366666 3008043 2866000 865477 1052056 1760704 0 0 916636 1414529 1020314 1249472 0 403543 0 0 1505332 0 0 0 2027707 1877777 0 1186142 1094406 0 0 0 0 0 0 0 0 292936 0 146941 0 0 0 382469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222399 0 337476 487284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVQDGKITVNGK MGYG000002492_00430 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,25UXG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1371371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 482888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVQDGKITVNGKDYVVR MGYG000002492_00430 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,25UXG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVS(Deoxy[S](Ser->Ala)LVGTEK MGYG000000201_01077 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066145|m__MGYG000000201 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2266125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3909396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16068368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVSEPATTETPAEEIVSEKPVEPVQK MGYG000001346_03509 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,4AKEY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 685452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 229512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVSLVGTEK MGYG000000201_01077 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066145|m__MGYG000000201 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 331094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178262 0 1349597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 693019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380443 0 886388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 738817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 584514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 638328 0 510982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1699651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1531685 0 872916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEVTLVGTEK MGYG000000249_01483;MGYG000004799_00497;MGYG000000268_01898;MGYG000000127_01922 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1921446 1678116 1964606 1869886 1889936 0 0 1887455 1414787 1838995 2047891 0 2127696 1693844 1615013 1708160 2593188 0 1887356 0 4552267 0 1454436 0 1757189 1599069 1608983 1635090 0 0 0 1730589 2040704 2209595 1863595 0 1785341 1797936 10148116 5757080 6033940 7289290 8033915 0 0 6941689 8307852 3569740 4550835 0 3042822 6401097 6916558 2243464 20935100 8259546 5675174 0 7579854 0 6167065 0 6600427 8095281 7524045 6780824 0 7079063 0 5643792 6276397 7680232 10765272 0 9514242 8703476 4474486 2986795 4137231 4277043 4797063 0 0 4330271 0 5284799 4053234 0 2874460 4093167 4338072 0 3627672 9282383 4084872 0 3541226 0 9427356 0 4023672 4486320 4277717 6520464 0 2371215 0 4421213 3096015 4441184 3137762 0 4258093 3902706 1983030 2462623 2367536 2545521 2139071 0 0 1857973 1960493 2506869 2104005 0 2586686 1986893 1774038 1693484 7714646 2977167 1257082 0 3619437 0 3528317 0 1912835 1668875 2091264 4567060 0 3164427 0 1810049 3025570 2149309 1953670 0 1743196 2381553 913993 264465 802516 1332276 0 0 0 996416 711621 463147 0 0 686742 668555 0 624601 3994830 0 0 0 721676 0 0 0 680262 442822 0 2756294 0 982533 0 683224 696419 817964 665355 0 0 403633 -AAEVVGK MGYG000002545_01217;MGYG000002274_02693;MGYG000000022_02788;MGYG000003899_02226;MGYG000002224_02000;MGYG000003166_00833;MGYG000003921_00033;MGYG000001300_02837;MGYG000001255_00900;MGYG000002040_00906;MGYG000000039_02141 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 246105 1041285 171428 425477 235115 58195 40206 0 0 347540 0 0 150294 621323 556221 0 163585 478829 293578 0 273084 132793 382453 273123 271996 328016 290486 261546 0 0 1293607 0 444080 0 172886 100910 268340 483042 1049829 189624 57098 206613 689939 1393227 707904 0 0 399768 0 0 928773 1034387 542831 0 1419710 589703 970740 407771 801223 1419885 1509614 1022911 856991 604954 706705 608922 0 0 1151083 0 617542 0 703867 494393 421762 451717 386095 220828 58327 343068 148723 140435 223248 0 0 256149 0 0 403527 122662 163115 0 595362 0 209206 231502 262466 284044 250479 867678 381933 799933 180906 87250 0 0 238548 0 338570 0 350215 311147 159700 291038 490233 488280 321671 72505 122117 0 1804797 0 0 125474 0 0 1221150 438018 212731 0 447861 335107 614927 620634 1248753 223066 966391 403237 483512 555927 564721 2149409 0 0 350490 0 505686 0 872844 738715 541837 257447 526133 1393113 145695 140515 73951 71117 240335 0 0 90554 0 0 59448 295078 229416 0 867568 174034 87051 228941 152852 350110 82589 110710 127748 218536 407487 1346459 0 0 60164 0 466764 0 332052 277502 140929 35554 -AAEVWANIEENKR MGYG000000099_00313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,268MU@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Ribosome;Metabolic pathways;Biosynthesis of secondary metabolites;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 225429 0 118082 0 0 0 0 485017 0 0 0 0 0 0 0 0 0 0 0 0 0 87874 0 0 0 0 0 0 110058 0 0 0 0 0 0 0 0 0 866781 0 820444 0 0 0 0 993677 0 0 0 0 637858 0 0 0 0 0 0 0 0 626252 0 0 0 0 727184 0 644980 0 0 0 0 0 0 0 0 0 277388 0 202724 0 0 0 0 180357 0 0 0 0 255014 0 0 0 0 0 0 0 0 0 0 0 0 0 278213 0 0 0 0 0 0 0 0 0 0 0 99252 0 614561 0 0 0 0 644625 0 0 0 0 0 0 0 0 0 0 0 0 0 306122 0 0 0 0 219535 0 250509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114573 0 0 0 0 0 0 91589 0 0 -AAEWGATEQNQATVGR MGYG000002478_01138 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG3883@1|root,COG1196@2|Bacteria,COG3883@2|Bacteria,4P07U@976|Bacteroidetes,2FN9Y@200643|Bacteroidia,4APBT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 nuclear chromosome segregation 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Collagen,DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 349087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEWLNAYTTAK MGYG000001338_03290 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3Y1DY@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K02058 1.0 - 1.0 M00221 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1.2 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1159094 0 0 407786 169584 650038 0 0 2144843 679636 0 198797 0 429566 0 0 0 0 0 382069 0 204127 0 0 0 0 0 0 0 0 328780 0 0 0 0 349435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291618 0 279791 0 0 0 0 0 0 0 0 262562 0 0 0 0 0 0 0 0 0 0 0 331718 142774 0 0 0 0 0 149425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 851436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 626084 0 0 432886 789613 555592 0 0 943236 847272 0 788885 0 798056 0 0 0 0 0 544466 0 653388 0 0 0 0 0 0 0 0 963603 0 0 0 0 637142 -AAEYAALQSSAVAAAK MGYG000004735_00145 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1307692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEYAALQSSAVAAAKR MGYG000004735_00145 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1200529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEYAGGDPAK MGYG000002438_00932 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,22WE8@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEYAR MGYG000003279_01589;MGYG000000003_01532;MGYG000001346_03588;MGYG000000003_02653;MGYG000002753_00262 domain d__Bacteria 1.0 COG0702@1|root,COG0702@2|Bacteria,4PNS2@976|Bacteroidetes,2G0WT@200643|Bacteroidia 0.4 976|Bacteroidetes 0.8 GM 0.4 Pfam:SusD 0.4 - 1.0 - 1.0 - 1.0 ko:K21572 0.6 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 0.6 8.A.46.1,8.A.46.3 0.6 - 1.0 - 1.0 SusD-like_3,SusD_RagB 0.8 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1354180 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 971500 0 0 0 936508 0 0 1028215 0 0 1056771 0 0 1472341 1277022 813656 0 0 0 1267082 0 0 0 0 0 0 0 0 1574365 0 0 0 0 0 0 0 0 54060 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234068 0 0 0 0 0 0 0 1379544 0 1729319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEYATLQNNVTSAAR MGYG000000251_00721 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter saccharivorans|m__MGYG000000251 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3XZR6@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Acetyl-CoA carboxylase alpha subunit 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 842271 0 0 0 0 0 570273 0 0 0 0 410221 0 0 0 0 534691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1071898 0 0 0 0 0 552962 0 0 0 0 210987 0 0 0 0 179608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392547 0 0 0 0 513270 0 0 0 0 678907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265464 0 0 0 0 484131 0 0 0 0 537973 0 0 0 0 0 0 0 0 0 0 -AAEYDKNTR MGYG000001292_00824 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG1566@1|root,COG1566@2|Bacteria,2I2G9@201174|Actinobacteria,4CZ5W@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 V 1.0 DivIVA protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DivIVA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 41141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEYIYNAYK MGYG000001496_03152;MGYG000001954_02140;MGYG000001619_01035;MGYG000001607_02072;MGYG000000179_02579;MGYG000001367_03149;MGYG000000146_01010;MGYG000003355_03067;MGYG000000909_01807;MGYG000004087_01471;MGYG000003822_00610;MGYG000000198_05065;MGYG000000133_00993;MGYG000000301_01128 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,2686V@186813|unclassified Clostridiales 0.42857142857142855 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 0.7142857142857143 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 767088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739790 0 0 0 0 -AAEYLEEPIDR MGYG000003937_01664 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1005799 0 0 0 0 898154 0 0 0 0 1207795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEYLEEPIDRLK MGYG000003937_01664 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 717057 0 0 0 0 0 0 0 1489787 0 0 0 0 0 0 0 1489267 0 0 0 0 894021 0 0 0 0 1197097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245018 0 0 0 0 0 0 0 0 0 194560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128428 0 0 0 0 0 0 0 271663 0 0 0 0 0 0 0 0 0 375235 0 0 0 0 0 0 0 0 0 0 0 225142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEYLEEPIER MGYG000002545_01147;MGYG000002040_00963;MGYG000000195_02140;MGYG000001300_02904;MGYG000001627_01221;MGYG000002274_00855;MGYG000002651_01056;MGYG000003921_01150;MGYG000002619_01707;MGYG000000022_02047;MGYG000003899_00603 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 1898984 2096936 2583105 2316659 693426 1902508 1966994 1559583 2263091 2093798 2359977 1816689 2037615 2062783 1528468 2130575 2402891 7274087 2217778 2286607 1668755 2226267 6001293 2000907 2208100 2102613 1818189 6607310 1953498 1935278 2134984 1701079 2311502 2352602 1884989 1993559 2369673 2563758 2243354 1578423 2013751 1874188 1454602 1700256 2146142 1411641 2307015 1273938 1641424 1532066 1702111 2133956 1892293 1584452 2040295 7553698 2424019 2149373 483746 1613767 8550944 1800131 2431697 1947030 2082956 7448246 965285 1818781 1898118 1637427 1796815 2255995 1369664 2099789 2097236 1835049 1472493 1695535 2129035 2204781 2690069 2289165 2679065 1679066 2567316 1920287 2418740 2573153 2050670 2337650 1733165 1817606 2103520 7634636 1292020 1686935 2119686 2096079 7705101 992123 2096033 1860745 1499169 9064174 2126879 2297477 2712285 1768123 1825797 2090039 1919814 2218645 2130537 2498606 1679937 2362364 2957085 2196334 2371151 2990089 3106684 2233625 2513734 2630319 2722022 2940201 2728531 2099904 2428258 2285725 2371127 8328895 2763982 2258142 2491565 3562333 7134083 2707743 2387637 2128501 2165439 9367521 1745709 2443127 3197168 2037272 2797722 2587584 1469784 2313629 2081486 2845982 501388 836851 1160466 885421 734950 780374 1003091 1023396 847229 1015607 859661 362847 883728 874419 0 870068 890210 4538288 530288 781645 767814 751144 6976970 1083828 0 579648 815350 8009216 645560 764147 817208 717652 1073898 938495 762244 417578 840430 1151427 -AAEYLEEPIERLK MGYG000000022_02047;MGYG000003899_00603 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAEYPIHYDWGK MGYG000000278_00219 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA3402|s__UBA3402 sp003478355|m__MGYG000000278 1.0 COG2222@1|root,COG2222@2|Bacteria,1TRTA@1239|Firmicutes,24BGB@186801|Clostridia,21ZI4@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 M 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 ko:K10708 1.0 - 1.0 - 1.0 R08125 1.0 RC00053,RC01805 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 SIS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71074 0 0 0 0 103426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1874117 0 0 0 0 1914678 0 0 0 0 1802907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994301 0 0 0 0 988314 0 0 0 0 978446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114527 0 0 0 0 0 0 0 0 0 0 -AAEYSGSEDAWK MGYG000000243_02605 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1429500 1971028 3755417 1667307 2448347 1391534 2110123 1386610 0 0 0 0 1576853 1591435 0 1497698 1276356 647891 1296437 1248700 0 928807 1271875 1811804 0 1508634 0 1064807 1249512 1644043 4395356 1609761 4516016 1935335 1538035 0 1527856 3411809 820723 0 353013 0 963495 0 0 0 0 0 0 0 602601 712831 0 650403 127602 0 382016 0 0 0 324579 0 0 733124 0 563312 0 661062 534952 0 393626 607030 646379 0 682935 955799 892446 0 707766 413933 647296 0 854415 468489 0 0 0 0 592023 482635 0 957232 1033184 0 724413 777673 0 0 0 0 0 765907 0 351139 347014 429990 716937 413055 771281 195116 545884 0 1133004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAF(Phe->Asp)GVILITTK MGYG000002171_02947;MGYG000000243_00119 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1207250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAF(Phe->Asp)GVVLITTK MGYG000000236_00639;MGYG000003693_02994;MGYG000001780_03070;MGYG000001313_00646;MGYG000002171_00975;MGYG000000243_01524;MGYG000001787_00483;MGYG000003681_02851;MGYG000001364_00903;MGYG000000243_02728;MGYG000000138_01891 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.9090909090909091 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6363636363636364 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 901434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAF(Phe->Gly)GVILVTTK MGYG000000042_02037;MGYG000002478_01844;MGYG000001415_00852;MGYG000002478_00434;MGYG000001337_00976;MGYG000001337_04109;MGYG000002203_01364;MGYG000000003_01805;MGYG000003279_01059;MGYG000000236_03728;MGYG000000273_01279;MGYG000003363_02700;MGYG000004756_00447;MGYG000000236_01449 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.7857142857142857 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec 0.5714285714285714 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1097423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFA(Ala->Asp)KFMETK MGYG000000262_01692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1412437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1391091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 650139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFAEAK MGYG000004735_02771 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25VDM@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Transketolase, thiamine diphosphate binding domain protein 1.0 tktA 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Hydrolase_3,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 575284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2642581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFAEAR MGYG000002517_02816 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Transketolase, thiamine diphosphate binding domain 1.0 tktA 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Hydrolase_3,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFAPPLDGAGNSVK MGYG000000003_01141;MGYG000000196_02443 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2066@1|root,COG2066@2|Bacteria,4NERJ@976|Bacteroidetes,2FM3D@200643|Bacteroidia 0.5 976|Bacteroidetes 1.0 E 1.0 Belongs to the glutaminase family 1.0 glsA 1.0 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.0 3.5.1.2 1.0 ko:K01425 1.0 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 1.0 - 1.0 R00256,R01579 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glutaminase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaminase. L-glutamine amidohydrolase. - H2O + L-glutamine = L-glutamate + NH4(+). 1.0 1.0 1.0 1.0 GABAergic synapse;Proximal tubule bicarbonate reclamation;Central carbon metabolism in cancer;Arginine biosynthesis;Metabolic pathways;MicroRNAs in cancer;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse 1.0 none 1.0 3099408 0 0 0 0 0 3244903 0 3747856 0 0 0 0 3285891 0 0 0 0 4020864 2667976 2768257 0 0 0 0 2850568 2291718 0 2376218 0 0 0 0 0 0 3211474 2559239 0 0 0 0 0 0 0 0 0 470502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182403 0 0 258203 0 0 0 0 0 309636 0 415368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFAWK MGYG000001056_00630;MGYG000002293_02867;MGYG000002960_00779 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 susC 1.0 - 1.0 - 1.0 ko:K21573 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14.6.1 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573651 0 0 0 0 1102375 0 0 0 0 1111266 0 0 2070799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1163470 0 0 0 0 998713 0 0 0 0 834806 0 0 884543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1078630 0 0 0 0 917645 0 0 0 0 919201 0 0 291771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2248226 0 0 0 0 2062858 0 0 0 0 1346722 0 0 0 0 0 0 0 0 0 0 -AAFDAADLPFDLHR MGYG000000022_00086 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3WGWD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 malonyl CoA-acyl carrier protein transacylase 1.0 fabD 1.0 - 1.0 2.3.1.39 1.0 ko:K00645 1.0 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 1.0 M00082 1.0 R01626,R11671 1.0 RC00004,RC00039,RC02727 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 Acyl_transf_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 [acyl-carrier-protein] S-malonyltransferase. MCAT. Essential, along with EC 2.3.1.38, for the initiation of fatty-acid biosynthesis in bacteria.-!-Also provides the malonyl groups for polyketide biosynthesis.-!-The product of the reaction, malonyl-ACP, is an elongation substrate in fatty-acid biosynthesis.-!-In Mycobacterium tuberculosis, holo-ACP (the product of EC 2.7.8.7) is the preferred substrate.-!-This enzyme also forms part of the multienzyme complexes EC 4.1.1.88 and EC 4.1.1.89.-!-Malonylation of ACP is immediately followed by decarboxylation within the malonate-decarboxylase complex to yield acetyl-ACP, the catalytically active species of the decarboxylase.-!-In the enzyme from Klebsiella pneumoniae, methylmalonyl-CoA can also act as a substrate but acetyl-CoA cannot whereas the enzyme from Pseudomonas putida can use both as substrates.-!-The ACP subunit found in fatty-acid biosynthesis contains a pantetheine-4'-phosphate cofactor; that from malonate decarboxylase also contains pantetheine-4'-phosphate but in the form of a 2'-(5-triphosphoribosyl)-3'-dephospho-CoA cofactor. holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis;Prodigiosin biosynthesis;Metabolic pathways;Fatty acid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71360 0 0 0 0 66149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124403 0 0 0 0 77981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158487 0 0 0 0 206937 0 0 0 0 131746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408761 0 0 0 0 390460 0 0 0 0 429668 0 0 0 0 0 0 0 0 0 0 -AAFDDAIAAR MGYG000002494_02707;MGYG000002534_04377;MGYG000003372_02551 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,3WVEI@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 O 1.0 HflC and HflK could encode or regulate a protease 1.0 hflK 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 1.0 - 1.0 ko:K04088 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Band_7,HflK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 443098 0 0 1059852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 872958 0 928725 0 0 0 0 0 703039 0 0 200602 0 0 0 0 0 0 0 1233999 0 0 2202456 0 0 0 0 0 0 0 0 0 0 1851512 0 0 0 0 2420253 0 2374529 0 0 0 0 0 1794882 0 0 2058537 0 0 0 0 1257723 0 0 330437 0 0 510106 0 0 0 0 0 0 0 0 0 0 223298 0 0 0 0 1015748 0 540818 0 0 0 0 0 620343 0 0 0 0 0 0 0 371284 0 0 908677 0 0 871532 0 0 0 0 0 0 0 0 0 0 364791 0 0 0 0 956188 0 0 0 0 0 0 0 619989 0 0 341045 0 0 0 0 611233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464847 0 0 0 0 0 0 0 0 -AAFDEAK MGYG000001338_02856;MGYG000002298_02139 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 tktA 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Hydrolase_3,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 2107047 1767422 0 0 1367521 0 0 0 2071561 0 1914332 2653085 1840094 2985795 0 0 1796229 2470549 2236219 2419956 2267696 1634065 515779 2456042 0 1643325 1667931 3876339 2225308 0 1991905 845212 0 2304981 1499481 0 1238255 0 1991289 0 0 0 0 0 0 0 1013458 0 479687 243380 0 224956 0 0 722512 0 183916 314333 181688 0 375022 278975 0 321594 0 1391220 395995 0 522493 0 0 0 0 0 561445 0 1370022 376073 0 0 651035 0 0 0 744622 0 385376 484810 644079 585706 0 0 64045 770870 790121 611100 795938 0 318490 635779 0 666735 314085 821799 564441 0 1491780 816849 0 563168 184206 0 439350 0 1124723 1066849 0 0 0 0 0 0 433392 0 112950 654909 135566 404132 0 0 527320 490056 329044 109677 1374006 139474 1235578 188940 0 451845 572948 3879869 726709 0 912113 980233 0 135587 152233 0 1191668 0 1547300 0 0 0 629579 0 0 0 604580 0 377475 544566 129819 209010 0 0 115149 96330 267797 400249 211159 428761 1023442 110120 0 530852 400318 726387 255441 0 1394893 2343612 0 522612 456655 0 950710 -AAFDEAR MGYG000004869_02367;MGYG000001642_01428;MGYG000000133_02556 domain d__Bacteria 1.0 COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia 0.6666666666666666 186801|Clostridia 0.6666666666666666 G 0.6666666666666666 Psort location Cytoplasmic, score 8.87 0.6666666666666666 tktA 0.6666666666666666 - 1.0 2.2.1.1 0.6666666666666666 ko:K00615 0.6666666666666666 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 0.6666666666666666 M00004,M00007,M00165,M00167 0.6666666666666666 R01067,R01641,R01830,R06590 0.6666666666666666 RC00032,RC00226,RC00571,RC01560 0.6666666666666666 ko00000,ko00001,ko00002,ko01000 0.6666666666666666 - 1.0 - 1.0 - 1.0 Hydrolase_3,Transketolase_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.6666666666666666 none 1.0 237510 0 0 0 0 0 0 0 0 97003 377549 570653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102242 0 0 0 0 0 0 0 0 0 0 0 253503 0 0 0 223824 0 0 76520 539664 398564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502841 0 0 0 747553 0 65301 0 0 208611 0 0 782968 0 443114 944011 0 518563 402894 0 343692 957804 655787 490208 232646 447391 810595 919715 753036 0 886211 0 623326 1238119 0 420060 817642 708259 812502 0 633369 0 485068 676955 830198 725845 0 469847 841083 695612 0 0 0 0 0 0 0 0 0 0 0 0 133805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152097 2784984 0 1980369 3308257 0 828918 2889369 0 1393679 3419738 3220530 2766565 1916328 6426991 3275261 1550194 2080940 0 2236414 0 4160896 1748834 0 1480583 2692595 2447370 3411252 0 3027299 0 1546565 2358424 4675252 2542153 0 3980803 1892837 1615342 -AAFDEAR(Arg->Lys) MGYG000004869_02367;MGYG000001642_01428;MGYG000000133_02556 domain d__Bacteria 1.0 COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia 0.6666666666666666 186801|Clostridia 0.6666666666666666 G 0.6666666666666666 Psort location Cytoplasmic, score 8.87 0.6666666666666666 tktA 0.6666666666666666 - 1.0 2.2.1.1 0.6666666666666666 ko:K00615 0.6666666666666666 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 0.6666666666666666 M00004,M00007,M00165,M00167 0.6666666666666666 R01067,R01641,R01830,R06590 0.6666666666666666 RC00032,RC00226,RC00571,RC01560 0.6666666666666666 ko00000,ko00001,ko00002,ko01000 0.6666666666666666 - 1.0 - 1.0 - 1.0 Hydrolase_3,Transketolase_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 2348079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1687940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 812362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732846 0 0 0 0 0 -AAFDEFM(Oxidation)ATK MGYG000002040_01920;MGYG000002545_01451 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1497359 0 0 0 0 352885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546382 0 0 0 0 687596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317734 0 0 0 0 390366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355880 0 0 0 0 331687 0 0 0 0 146198 0 0 0 0 0 0 0 0 0 0 -AAFDEFMATK MGYG000002040_01920;MGYG000002545_01451 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 1674143 1984022 2340740 2025239 1761549 2083810 2192008 0 2466491 0 0 0 1928344 0 1582461 1948606 2083427 6015745 0 1899297 1539653 1805739 6785808 1899298 1952794 2305176 2198931 7318055 0 0 2941544 1939811 1867783 0 0 1973654 1741589 2125598 350133 229811 615122 337691 470749 330492 424898 0 316791 0 0 0 451628 0 300607 502772 358266 7334507 0 283896 0 457186 9634420 397310 451243 389823 529499 7627547 0 0 412105 381542 592656 0 0 264485 380954 623070 921578 898938 1026725 1061474 1419100 1560942 1244225 0 1368938 0 0 0 1209392 0 853946 1149683 1320956 7072776 0 658237 835768 983361 6601838 1400039 915872 1020293 899558 7145239 0 0 1432680 1214301 703290 0 0 1269163 1142475 1175743 568614 276627 684377 475993 602701 603466 504509 0 489820 0 0 0 565618 0 488859 685363 552935 2965901 0 377095 581110 578964 3060521 643390 719356 429396 524129 2573361 0 0 644287 628558 599073 0 0 469696 658552 556893 0 0 181591 0 100959 185935 120347 0 166202 0 0 0 159628 0 0 251948 0 3357474 0 0 0 99134 3019474 166433 159628 167574 0 3174598 0 0 92578 0 129321 0 0 0 175356 107464 -AAFDFAVEHQSVER MGYG000002506_03405;MGYG000002477_00657;MGYG000002494_02407;MGYG000002323_04218;MGYG000002515_03906 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0056@1|root,KOG1353@2759|Eukaryota,38ERH@33154|Opisthokonta,3BCEE@33208|Metazoa,3CU79@33213|Bilateria,40ASR@6231|Nematoda,1KTUU@119089|Chromadorea,40X9Y@6236|Rhabditida 1.0 33208|Metazoa 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane 1.0 ATP5A1 1.0 - 1.0 - 1.0 ko:K02132 1.0 ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016 1.0 M00158 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_A,ATP-synt_B,ATP-synt_C,ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,GidB,OSCP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Thermogenesis;Alzheimer disease;Metabolic pathways;Oxidative phosphorylation;Huntington disease;Parkinson disease 1.0 none 1.0 0 456022 479396 0 0 586371 0 0 0 418207 0 0 0 0 0 0 0 0 493797 347593 0 571446 0 918806 280544 0 0 0 506196 0 0 0 567622 0 0 0 0 288748 0 1347155 1217272 0 1285422 1984204 0 0 0 1379409 0 0 0 0 0 0 0 0 1509251 919698 1688411 3400760 0 2581221 1586235 0 0 0 1654179 0 0 0 1317053 0 0 0 0 1339580 0 478717 427171 0 423292 950338 0 0 0 478479 0 0 0 0 0 0 0 0 419976 451746 460536 584477 0 982015 259371 0 0 0 457446 0 0 0 481467 0 0 0 0 458203 0 434963 532618 0 324619 730021 0 0 0 599031 0 0 0 0 0 0 0 0 442084 312231 232809 870416 0 733861 555712 0 0 0 327029 0 0 0 642445 0 0 0 0 323553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308458 0 0 0 0 0 0 0 0 0 -AAFDFLYASTK MGYG000003693_02097 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 29RCG@1|root,30CEM@2|Bacteria,4PHRC@976|Bacteroidetes,2FNH2@200643|Bacteroidia,4APWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Fimbrillin-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Mfa_like_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479445 0 0 0 0 1152733 0 0 0 0 620347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFDGTDFEIMETQYGEGDAAK MGYG000000201_01306;MGYG000000002_00716 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ95@1239|Firmicutes,24AX7@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 PFAM periplasmic binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 804155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFDHNYAK MGYG000001789_01365 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002161565|m__MGYG000001789 1.0 COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,2FMB3@200643|Bacteroidia,4AKGW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Inositol-3-phosphate synthase 1.0 ino1 1.0 - 1.0 5.5.1.4 1.0 ko:K01858 1.0 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 1.0 - 1.0 R07324 1.0 RC01804 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Inos-1-P_synth,NAD_binding_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 inositol-3-phosphate synthase. myo-inositol-1-phosphate synthase. The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the -CHO at C-1; finally, the enzyme-bound NADH reconverts C-5 into the -CHOH- form. D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Inositol phosphate metabolism;Streptomycin biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1191577 0 0 0 0 1517928 0 0 0 0 1334306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354496 0 0 0 0 291856 0 0 0 0 302864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80707 0 0 0 0 0 0 0 0 0 81289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629050 0 0 0 0 554327 0 0 0 0 357730 0 0 0 0 0 0 0 0 0 0 -AAFDHNYASR MGYG000004797_04061;MGYG000000243_01209 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,2FMB3@200643|Bacteroidia,4AKGW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Inositol-3-phosphate synthase 1.0 ino1 1.0 - 1.0 5.5.1.4 1.0 ko:K01858 1.0 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 1.0 - 1.0 R07324 1.0 RC01804 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Inos-1-P_synth,NAD_binding_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 inositol-3-phosphate synthase. myo-inositol-1-phosphate synthase. The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the -CHO at C-1; finally, the enzyme-bound NADH reconverts C-5 into the -CHOH- form. D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Inositol phosphate metabolism;Streptomycin biosynthesis 1.0 none 1.0 3070043 2856552 5921646 3815990 4248257 3238898 4202764 3066071 3671204 2714830 3264517 2877845 4580672 2752639 2692920 5711838 2851286 2131583 2937517 2949533 2984178 3142848 2866606 4031752 2424348 2778354 2839964 2502998 2738068 3813351 6048935 2785837 6703607 2580401 2944233 2923325 2561636 7411642 2524834 1115317 1539666 1715075 0 1433556 1394560 1899533 2671418 1555646 1867038 1316656 3401675 1601120 2043803 2360722 1481244 1209869 1344313 1117963 1194128 0 2234397 2980957 2655976 1239814 1326378 1699643 1340918 1372815 1055708 1613316 1439542 3224223 0 1712201 1160812 1546543 1448206 1283998 1899630 1534886 2754130 1770516 1742443 1182908 2080979 1718538 1605295 1601544 2822699 1436650 1507105 2330519 1795291 3231934 1581993 1424255 1419849 1180125 2283315 1888050 1580754 1645557 1698120 1782698 1498456 1200244 2207045 1129222 1219158 912043 1198105 1903283 1763103 1661239 283468 94590 438547 161469 225186 242023 361004 341024 280060 470125 333179 271463 446320 278524 275615 297932 228915 724062 300684 283971 266914 177321 84388 206288 342602 358223 298329 0 451686 301509 495229 305985 567389 112535 444585 269740 209707 339415 1334149 1339776 914679 948666 2779512 1347178 1459797 1641129 1301443 677315 957793 920587 3122399 1217006 1026365 2050086 1157227 2872476 1517617 1417882 860033 1546686 3083464 1262687 1786027 1542354 1345373 2468130 1269929 1507595 1131150 980522 1071169 1446151 2550222 1731253 1834206 1227362 -AAFDHNYASRLDGN(Deamidated)NVKDC(Carbamidomethyl)K MGYG000000243_01209 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,2FMB3@200643|Bacteroidia,4AKGW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Inositol-3-phosphate synthase 1.0 ino1 1.0 - 1.0 5.5.1.4 1.0 ko:K01858 1.0 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 1.0 - 1.0 R07324 1.0 RC01804 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Inos-1-P_synth,NAD_binding_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 inositol-3-phosphate synthase. myo-inositol-1-phosphate synthase. The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the -CHO at C-1; finally, the enzyme-bound NADH reconverts C-5 into the -CHOH- form. D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Inositol phosphate metabolism;Streptomycin biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFDITQLD MGYG000002515_02933;MGYG000002506_02717 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3XNX9@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 K 1.0 transcriptional regulator 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1846883 0 0 1965650 1018656 3308227 2604386 3912498 2636016 3723438 0 1644011 0 1872294 2423521 0 1758720 0 2404815 2150558 2668775 5124648 0 6052128 3019459 2508444 0 0 2416416 2847143 0 0 0 3278974 0 2538324 2085993 0 578172 0 0 595697 860373 2316730 766223 1338977 721073 1440003 0 717365 0 943182 993375 0 805161 0 1242534 989934 73624 2757515 0 2343321 913327 900394 0 0 601740 1134939 0 0 0 746269 0 661373 701785 0 1567778 0 0 1043884 940971 1610488 1425731 1720958 768188 1587265 0 1198117 0 1421414 1610441 0 955718 0 1736600 1883127 1245437 2848250 0 2711286 1881117 1688615 0 0 1578133 1538407 0 0 0 1727669 0 962440 1285796 0 2627084 0 0 2177958 1531281 2342934 2232208 2014532 2464365 2528829 0 1798560 0 2322138 2540644 0 1726222 0 2427335 2444832 2891430 1556628 0 2482956 1640791 1885453 0 0 2762456 2254883 0 0 0 83994 0 2600136 2796738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFDKFI(Xle->Met)ETK MGYG000004845_01965 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Monoglobales_A|f__UBA1381|g__UBA4716|s__|m__MGYG000004845 1.0 COG0479@1|root,COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0479@2|Bacteria,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3786917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFDKFMETK MGYG000000022_01634 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 70429 74132 64098 0 122492 75686 0 109469 0 138889 261163 0 70731 83250 0 158359 71040 451544 0 53551 197851 46238 515534 165091 130911 84595 133039 491271 123670 136816 160375 76600 76500 0 109326 0 81023 72215 300379 317411 295111 0 396194 389730 358103 456817 0 473724 812866 0 443996 426146 0 344527 302467 0 0 379058 151783 283723 0 310894 387585 407703 429792 3645661 385746 259139 365550 373428 284054 407946 257752 0 412548 447874 1480107 1410041 1503483 0 1210872 1490840 1500403 1532234 0 1788205 1527055 0 1218042 1765976 0 1433813 1444058 4436905 0 1237782 1251070 1324126 5026059 1682663 1711050 0 1668043 5027503 1488263 1460173 1690850 1556563 1361138 1710069 1736553 0 1751756 1428870 300822 450061 383884 0 382589 296860 343553 328485 0 402480 313798 0 311248 273523 0 177664 521114 1120557 0 201516 257141 306866 1012480 236948 226536 279570 387570 1789655 267388 295961 65594 254608 88346 206817 296560 0 279658 342807 623126 645053 1561291 0 465139 740389 1148275 821394 0 965884 703690 0 903324 745326 0 906883 698638 6596192 0 473721 1015664 867236 8604868 953076 707250 520789 415225 8249060 940761 483557 1213641 914453 1566541 631586 951777 0 534813 1095022 -AAFDKFT(Thr->Met)ETK MGYG000000389_00578 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900550935|m__MGYG000000389 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1341104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFDKFVETK MGYG000002517_00959;MGYG000000076_02414 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 904045 251248 232703 947056 297351 538003 392465 782021 596254 1188067 34730 509147 291891 665388 1113247 404115 868685 0 1490947 925968 881396 661341 0 361948 933795 880254 1077619 0 135303 480666 367163 0 98453 745076 601332 736563 752639 108470 98728 131913 0 63060 0 243229 0 0 0 0 305220 0 0 0 111828 51412 91907 0 93046 74749 186032 0 0 0 57826 94458 0 0 0 216950 0 0 0 136552 0 0 67053 0 1321388 165457 49072 961641 182313 299417 797745 875038 837457 650209 469281 683489 516664 939595 1041289 593540 922315 0 1007483 1048098 543698 287534 0 251546 1487955 1451976 1253442 0 331076 1158152 0 0 150364 646128 950798 753434 1732675 86150 5410016 1064694 950898 6004081 2512030 1535527 2580722 6999147 5849934 2667533 1802274 2759194 1656403 7307548 6128338 2340986 3874992 0 3731515 5914659 4001285 376096 0 542373 5757394 5377251 5854047 0 1253432 4319901 1245732 0 1078920 3679936 5666217 4927752 6565893 980352 3952719 3323890 5257266 73556 3343785 4771334 3734094 2987555 4286488 6571688 3642039 3975167 1158856 7740356 6211103 2951736 5668627 0 3832569 3006180 3061269 3293412 0 5121839 4953195 3293051 5291302 0 1144959 2328015 3053677 0 3452031 4022899 3046577 5459914 5408746 3879426 -AAFDKNYAK MGYG000002293_01708;MGYG000001164_01285;MGYG000002737_00956;MGYG000003697_00295 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,2FMB3@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 I 1.0 Inositol-3-phosphate synthase 1.0 ino1 1.0 - 1.0 5.5.1.4 1.0 ko:K01858 1.0 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 1.0 - 1.0 R07324 1.0 RC01804 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Inos-1-P_synth,NAD_binding_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 inositol-3-phosphate synthase. myo-inositol-1-phosphate synthase. The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the -CHO at C-1; finally, the enzyme-bound NADH reconverts C-5 into the -CHOH- form. D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Inositol phosphate metabolism;Streptomycin biosynthesis 1.0 none 1.0 0 0 679727 0 0 393288 0 0 0 0 0 0 0 0 0 0 0 608199 0 0 0 428708 413451 107434 0 0 0 332506 0 0 0 0 293692 0 0 0 0 195356 0 0 305519 0 0 248112 0 0 0 0 0 0 0 0 0 0 0 234972 0 0 0 350152 0 0 0 0 0 0 0 0 0 0 233053 0 0 0 0 53463 0 0 0 0 0 289675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272690 0 551723 0 0 0 0 0 0 0 0 579447 0 0 0 0 268226 0 0 2003236 0 0 1888080 0 0 0 0 0 0 0 0 0 0 0 2628840 0 0 0 1938219 1468897 1621890 0 0 0 3101546 0 0 0 0 1448711 0 0 0 0 1487224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFDYC(Carbamidomethyl)VENIR MGYG000001627_00502;MGYG000003937_00374;MGYG000000084_00490 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 349278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 744303 0 0 0 0 538279 0 0 0 0 1473620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFE(Glu->Asp)KFMETK MGYG000002274_02671 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_I|m__MGYG000002274 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 69141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3184323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1658050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1817554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEAIDQN(Deamidated)TVR MGYG000004866_01550;MGYG000003937_01091;MGYG000000084_00623;MGYG000002059_01523;MGYG000001761_00369 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1993339 0 1825383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEAIDQNT(Thr->Ala)VR MGYG000004866_01550;MGYG000003937_01091;MGYG000000084_00623;MGYG000002059_01523;MGYG000001761_00369 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4145320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 229812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEAIDQNTVR MGYG000004866_01550;MGYG000003937_01091;MGYG000000084_00623;MGYG000002059_01523;MGYG000001761_00369 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 4367722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2287814 0 0 0 0 0 0 0 0 0 2426335 0 4604511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4693682 0 0 0 0 0 2986975 0 0 0 0 3324426 0 0 0 0 4064727 0 2055339 0 0 0 0 0 0 0 0 -AAFEAVDQAA(Ala->Ser)IR MGYG000003899_01136 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539945|m__MGYG000003899 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 1439813 0 0 0 0 0 0 1197022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEAVDQE(Glu->Ala)TVR MGYG000001300_00295;MGYG000003166_01334 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 1105589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1335191 0 0 0 0 0 0 0 0 0 0 0 0 352962 0 0 0 0 0 0 0 0 545177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 562020 0 0 0 0 0 0 0 0 0 0 0 0 607328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2240401 0 0 0 0 3753755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4129601 0 0 0 0 0 0 0 0 0 3934117 0 0 0 0 0 320150 0 0 0 0 -AAFEAVDQE(Glu->Asn)TIR MGYG000000039_00171;MGYG000000022_01324;MGYG000004679_00524;MGYG000002040_01715;MGYG000001255_01114 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 597158 0 0 0 575533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 529666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 818247 0 0 0 0 896286 0 0 1706048 0 0 0 1901099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1079624 0 0 0 0 1452643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339976 0 0 0 0 0 -AAFEAVDQE(Glu->Gln)TVR MGYG000001300_00295;MGYG000003166_01334 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2224764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEAVDQE(Glu->Gly)TIR MGYG000000039_00171;MGYG000000022_01324;MGYG000004679_00524;MGYG000002040_01715;MGYG000001255_01114 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1111527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6107724 0 0 0 0 6062760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1758810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3786452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEAVDQETI(Xle->Val)R MGYG000000039_00171;MGYG000000022_01324;MGYG000004679_00524;MGYG000002040_01715;MGYG000001255_01114 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3731171 0 2254089 3261002 0 0 0 0 0 1575673 0 0 0 2321005 0 0 0 0 0 2298589 0 1298972 0 1521905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11808844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEAVDQETIR MGYG000000039_00171;MGYG000000022_01324;MGYG000004679_00524;MGYG000002040_01715;MGYG000001255_01114 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 626037 0 0 1017929 0 451694 0 0 574757 0 864830 0 0 0 0 0 0 0 0 721517 0 638979 0 0 0 0 163521 0 0 0 443255 0 0 0 0 258071 0 0 0 3002187 0 1400908 1706604 0 0 0 0 0 1086499 0 0 0 0 8957515 0 0 0 1273577 10727583 0 0 0 0 8564849 0 0 0 0 0 0 0 0 0 0 1673510 0 1389720 1499422 1031147 1158821 1070478 1477305 0 1604340 1111937 0 1101516 1409833 0 0 0 3609104 0 1136960 0 1347988 3720639 1244998 1838131 1912653 0 3869085 1209561 0 0 0 1099335 1831098 2407724 0 1779528 984300 0 0 0 0 1221442 1045285 836437 764399 0 1590336 758279 0 0 0 0 0 0 1710896 0 781694 0 756402 1836547 890126 0 683432 0 1504996 1661612 0 0 0 1468098 0 0 0 894654 1324692 0 0 0 0 585563 0 0 0 0 1600466 0 0 0 0 0 0 0 7625771 0 0 0 6017650 8440453 0 1189305 0 0 9317366 1079338 0 0 0 0 1272874 5697177 0 0 6368474 -AAFEAVDQETV(Val->Xle)R MGYG000001300_00295;MGYG000003166_01334 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1231124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1096332 0 0 0 0 0 0 0 0 3602774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1853401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEAVDQETVR MGYG000001300_00295;MGYG000003166_01334 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 14992539 18575043 28815378 26545334 2665685 11763186 10455312 7138001 13354323 14037801 9581939 0 18210118 14143546 11821315 16337275 17154233 3781717 28138188 22775286 5286537 12577168 4148690 14200905 15937489 15773126 14957306 5574330 1345855 5775835 16422982 9556687 23872411 24045499 7271686 13950578 11702730 21896039 22117278 32720129 31967734 17874800 19661062 37145527 28214444 8756602 24704588 3653247 15662968 23600032 27380359 27944587 23934865 19698725 24046017 4348424 30396088 24570211 9127581 31512821 5510683 35420297 39184233 18909129 19177387 5329529 3516838 21559661 39198566 31648552 36801887 22104868 7350890 19676812 19314836 30251071 0 3847225 0 0 0 0 3718738 1981754 3038864 0 3689522 0 3563733 0 2355852 2771126 0 0 2428647 0 2202934 0 3736683 0 2020711 0 0 4028161 1046385 2406636 4060155 0 0 4247069 0 2712223 2720762 0 12474954 15858838 30227632 13465160 22806731 20811364 24815545 4318961 21035242 14039768 17775982 31232110 24739895 18535163 15035606 18014614 15230092 11117674 26754555 17545658 18177018 16713765 0 15229321 19449311 16012096 13528197 9502637 5897900 21527731 30271511 20060462 31516521 24344892 2535813 12827010 18440282 28446115 349607 0 398085 466250 139819 0 0 384999 0 1089163 0 686597 0 0 415854 0 277145 1282408 0 374217 557136 0 1919981 635597 547579 299704 0 1395367 654726 0 509861 0 551762 335165 0 550423 602793 0 -AAFEAVDQN(Deamidated)TIR MGYG000002274_00044 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_I|m__MGYG000002274 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 7798530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2769374 1198303 0 0 0 0 0 2193406 0 0 0 0 1680514 4596584 0 0 3362403 0 0 0 0 2954412 2260139 0 0 0 0 3315347 0 0 0 0 0 2324620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1803891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEAVDQNTIR MGYG000002274_00044 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_I|m__MGYG000002274 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 2884964 0 3548911 0 4044108 3371897 0 0 3696156 0 4291223 2891330 4110249 0 0 0 0 7115641 0 0 3377611 3474931 4940275 3121669 0 4305602 0 6461025 0 0 2057127 0 2763489 0 0 2850245 3060948 3153008 0 0 567155 0 322307 557440 0 0 645796 0 472475 432631 409127 0 0 0 0 939692 0 0 406180 0 728911 386540 0 0 0 736881 0 0 524382 0 0 0 0 429006 566634 265315 0 0 4775212 0 4229804 3531666 0 0 1918409 0 1553251 5773538 1797072 0 0 0 0 2326173 0 0 5335352 0 2274193 3589657 0 1425979 0 942094 0 0 4556671 0 3104614 0 0 4909671 5711891 5272212 0 0 0 0 2045886 0 0 0 1193876 0 6673114 0 0 0 0 0 0 8450030 0 0 0 0 9794438 7654821 0 0 0 11094775 0 0 6264364 0 5427734 0 0 4268971 0 5897835 305179 0 0 0 0 381100 0 0 0 0 0 0 868992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 965660 0 0 0 0 0 0 0 -AAFEAVDQSAIR MGYG000002545_00548 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_G|m__MGYG000002545 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5567988 0 0 0 0 5877396 0 0 0 0 5916066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7560821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEAYK MGYG000003012_02916;MGYG000000133_02295;MGYG000001338_02552 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XZ67@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 E 1.0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins 1.0 iscS 1.0 - 1.0 2.8.1.7 1.0 ko:K04487 1.0 ko00730,ko01100,ko04122,map00730,map01100,map04122 1.0 - 1.0 R07460,R11528,R11529 1.0 RC01789,RC02313 1.0 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 cysteine desulfurase. cysteine desulfurylase. The sulfur from free L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors.-!-The enzyme is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin).-!-In Azotobacter vinelandii, this sulfur provides the inorganic sulfide required for nitrogenous metallocluster formation. [sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine. 1.0 1.0 1.0 1.0 Thiamine metabolism;Metabolic pathways;Sulfur relay system 1.0 none 1.0 808506 1061689 0 957907 0 1044617 0 0 0 0 755273 614980 1004837 1214072 0 1460935 0 0 0 0 1023454 782691 0 1188920 0 754077 0 0 690719 0 1949762 1081725 0 0 0 0 1044137 0 436955 0 299250 184327 0 97070 0 0 0 0 246055 0 332629 204864 0 245137 0 0 0 0 219161 153993 0 345471 0 0 0 0 146835 0 0 116124 372004 0 0 0 0 0 0 0 0 0 0 543923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122431 0 0 0 0 0 0 0 119707 0 0 0 0 127109 0 0 0 0 0 0 0 394230 0 0 0 0 0 0 0 0 0 0 0 0 0 214412 958277 2213292 1372525 1872831 0 753181 0 0 0 0 2015262 1644062 1374152 1646396 0 1602837 0 0 0 0 2537903 1987298 0 1104742 0 930256 0 0 1338491 0 1356695 3040879 2935430 0 0 0 544395 1131219 -AAFEEAEHAAK MGYG000003509_00509;MGYG000000177_00118;MGYG000002026_00456;MGYG000003891_00390;MGYG000004769_01404;MGYG000000198_03730;MGYG000000172_04155;MGYG000004087_01663;MGYG000001434_00926;MGYG000000198_03710;MGYG000004087_01662;MGYG000001564_01103;MGYG000001311_01511;MGYG000001493_02801;MGYG000001493_02800;MGYG000003422_00075;MGYG000004713_00792 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,21YU6@1506553|Lachnoclostridium 0.5294117647058824 186801|Clostridia 0.8823529411764706 C 1.0 Rubrerythrin 0.6470588235294118 rbr3A 0.9411764705882353 - 0.9411764705882353 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.8823529411764706 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 4244759 4202530 3211781 4121308 2802847 3042565 2926887 3356840 3304269 4015268 3342626 3458009 3050535 3521301 3110091 3230034 2695244 4320894 3107643 3797249 4623841 3213635 671684 3478431 2945439 3148586 2981065 4679049 3533223 3742562 892899 2802056 2456742 3628139 2862794 2685399 3635889 2587444 1266167 1268699 1314355 946176 1378790 1666185 1177722 1236139 1350914 1517036 1872186 1205285 1412866 1267281 1106236 1353098 1516234 841395 1184617 1027979 1339901 1274189 783561 1538306 1085844 1170023 1143072 807452 1374248 381269 1457499 1227130 1575609 1274384 1076668 1189678 1262666 1489539 5321852 3431710 4223115 4291332 3736855 3440077 4159373 4702742 4148994 5345754 3592989 3508718 3437321 4789199 5189881 3714105 3411648 957039 5001065 5294758 4281467 3264152 2882092 4662580 4034945 5718979 5226269 2907574 4279975 4211620 3296294 3457139 4229335 4606746 2664041 4610412 4467945 3847457 1250174 1039053 1819252 753964 1327109 1537145 1107847 1176505 1031254 1940913 1509225 1365401 1792126 1113118 1057493 1152941 1276068 1537116 1569451 733681 1228693 1430052 1044890 1884401 1314585 1458003 1133738 1746560 1500769 1079524 1394059 1545177 2361605 1337829 1248903 1878718 1195835 1789601 4803013 3125577 3865891 8069281 4358963 3986457 4802657 3715600 5672067 5726838 4527540 3963163 4292895 4763740 5295242 2877745 5900433 2330182 3803472 5389732 3782577 4913342 3339353 5607617 4730417 7405878 5528896 0 3134379 4138779 4651561 4162578 3911753 5263109 2915746 8074649 5761429 4489780 -AAFEGETGK MGYG000000187_00431 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,25VUF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1277163 0 0 0 0 1276880 0 0 0 0 1149829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251261 0 0 0 0 346953 0 0 0 0 343161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355390 0 0 0 0 585811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 512326 0 0 0 0 1022335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEGVTGQMVALKR MGYG000002224_01133;MGYG000002651_00394;MGYG000002641_02047;MGYG000000022_01099 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3WHGE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481237 0 0 0 0 689118 0 0 0 0 627594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582130 0 0 0 0 674971 0 0 0 0 703303 0 0 0 0 0 0 0 0 0 0 -AAFEHAK MGYG000000074_02552 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,2FMVJ@200643|Bacteroidia,22UAM@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 - 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DUF1398,Metalloenzyme,PglZ,Phosphodiest,iPGM_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 46842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 491041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEKGEKAE MGYG000001300_01309 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WGTC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 P 1.0 Belongs to the ABC transporter superfamily 1.0 oppD 1.0 - 1.0 - 1.0 ko:K15583 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 ABC_tran,oligo_HPY 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 272219 0 0 524631 0 407501 225068 0 0 0 0 0 0 0 0 0 0 0 623506 420234 0 231940 0 246788 234953 225488 326222 0 0 0 0 0 0 0 0 0 372697 0 584791 0 0 828032 0 448319 991378 0 0 0 0 0 0 0 0 0 0 0 879299 671581 0 176802 0 230651 951398 717372 740764 0 0 0 0 0 0 0 0 0 547304 0 31864 0 0 131670 0 477206 73463 0 0 0 0 0 0 0 0 0 0 0 304498 316594 0 451705 0 0 462808 481561 225051 0 0 0 0 0 0 0 0 0 175808 0 599605 0 0 526285 0 696576 545993 0 0 0 0 0 0 0 0 0 0 0 622068 569007 0 686207 0 487953 580558 710503 512135 0 0 0 0 0 0 0 0 0 248991 0 464190 0 0 797299 0 675337 812715 0 0 0 0 0 0 0 0 0 0 0 344284 367291 0 417327 0 563400 516582 723773 346432 0 0 0 0 0 0 0 0 0 828466 0 -AAFESVK MGYG000003891_01893 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG2730@1|root,COG2730@2|Bacteria,1UYCF@1239|Firmicutes,24989@186801|Clostridia,27KIY@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Cellulase (glycosyl hydrolase family 5) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Cellulase,RicinB_lectin_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1405973 0 0 0 0 1567497 0 0 0 0 1430597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320275 0 0 0 0 115878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 960997 0 0 0 0 496947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFEYAQNTLNQTK MGYG000002438_03281 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0845@1|root,COG0845@2|Bacteria,4NIZF@976|Bacteroidetes,2FN5T@200643|Bacteroidia,22Y8A@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1333263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 790584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1752517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFFIC(Carbamidomethyl)GADR MGYG000003022_00152;MGYG000003352_02357 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VZYA@28216|Betaproteobacteria,4PQ6E@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 214091 0 200177 0 255978 0 0 302307 0 0 0 0 0 0 0 0 0 0 0 272355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155122 0 0 113827 990938 0 727168 0 1011174 0 1012769 1696469 800654 973170 0 0 0 0 0 0 0 0 851911 854058 0 0 0 0 0 798258 0 0 882942 0 0 0 897316 0 1404997 0 996015 861469 411732 0 409451 0 486320 0 455624 1195931 532849 339233 0 0 0 0 0 0 0 0 524222 197430 0 0 0 0 0 485387 0 0 424725 0 0 0 564789 0 1530316 0 669396 452803 276171 0 330521 0 210909 0 181153 300002 460858 221031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311119 0 0 161315 0 0 0 190298 0 322665 0 321224 281807 108503 0 447357 0 199647 0 207424 200003 242705 0 0 0 0 0 0 0 0 0 410035 215153 0 0 0 0 0 188867 0 0 290696 0 0 0 253224 0 395408 0 315610 277332 -AAFFMDDYIGGR MGYG000000212_02891;MGYG000002492_00205;MGYG000000251_02552;MGYG000002279_01884;MGYG000000389_01919;MGYG000002992_01779 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 G 0.8333333333333334 Belongs to the GPI family 0.3333333333333333 pgi 0.8333333333333334 - 1.0 2.2.1.2,5.3.1.9 0.8333333333333334 ko:K01810,ko:K13810 0.8333333333333334 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 0.8333333333333334 M00001,M00004,M00007,M00114 0.8333333333333334 R01827,R02739,R02740,R03321 0.8333333333333334 RC00376,RC00439,RC00563,RC00604 0.8333333333333334 ko00000,ko00001,ko00002,ko01000,ko04147 0.8333333333333334 - 1.0 - 1.0 - 1.0 PGI,TAL_FSA 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. | glucose-6-phosphate isomerase. glycerone transferase. | phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 0.8333333333333334 none 1.0 0 0 312390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 784250 0 864694 0 0 0 529993 0 621934 0 0 0 509692 0 0 509422 0 0 0 761353 0 0 0 0 824817 700847 657152 0 0 0 0 0 782173 807783 766417 853747 790108 743231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFGDTLVEDYNVR MGYG000000089_01490 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 1.0 rpsC 1.0 - 1.0 - 1.0 ko:K02982 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1138421 0 0 0 0 1219987 0 0 0 0 1531169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFGLK MGYG000001496_03152 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Extibacter|s__Extibacter sp001185345|m__MGYG000001496 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575423 0 0 0 0 560257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFGVILINTK MGYG000001346_02330 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 324270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 538110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 677649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFGVILITTK MGYG000002171_02947;MGYG000000243_00119 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 411851 533608 1291544 691437 543238 0 0 528234 673355 0 314897 466011 0 0 0 323316 636554 0 0 0 0 0 0 0 0 393160 470258 0 712959 0 1191754 548734 1167538 711331 0 513300 575703 1180485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159481 0 253871 115153 447261 0 0 105208 270357 0 284905 328201 0 0 0 243450 0 0 0 0 0 0 0 0 0 123185 0 0 207555 0 374895 0 145447 0 0 280601 257271 190619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFGVILVTTK MGYG000000042_02037;MGYG000002478_01844;MGYG000001415_00852;MGYG000002478_00434;MGYG000001337_00976;MGYG000001337_04109;MGYG000002203_01364;MGYG000000003_01805;MGYG000003279_01059;MGYG000000236_03728;MGYG000000273_01279;MGYG000003363_02700;MGYG000004756_00447;MGYG000000236_01449 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.7857142857142857 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec 0.5714285714285714 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1566280 2081402 1235950 2114886 1171273 1788056 1511705 1231955 1986967 2214013 987007 2683014 1318443 1511615 1874270 1413801 2273872 0 1361837 1342594 1854483 1501648 0 2116324 1819190 2128297 2912127 0 1743753 3587455 1725404 1857143 1417438 1130496 1746143 1790730 2107879 1132454 0 0 146799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147834 0 0 0 0 0 0 0 0 0 161395 0 0 0 0 0 0 1839379 876981 1736240 1542235 1605077 669634 2138927 1823036 1993525 1479763 1106781 1993201 1138519 1640000 1716233 878986 1042234 0 1529715 2184215 2083311 645919 0 1124969 1685033 1645607 1645655 0 1509312 2527068 1012666 800230 1636976 2172099 1462686 2406950 1722247 1713121 213968 0 0 0 110858 0 138114 198060 123476 111109 0 310951 192966 215287 182568 118665 0 0 139577 150290 198329 0 0 0 301431 301313 193498 0 0 0 131803 253961 259669 367962 167319 245541 441507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFGVVLITTK MGYG000000236_00639;MGYG000003693_02994;MGYG000001780_03070;MGYG000001313_00646;MGYG000002171_00975;MGYG000000243_01524;MGYG000001787_00483;MGYG000003681_02851;MGYG000001364_00903;MGYG000000243_02728;MGYG000000138_01891 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.9090909090909091 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6363636363636364 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1186613 662410 420244 0 0 0 0 0 0 0 390474 401793 0 0 531874 0 0 0 0 0 322651 0 0 0 0 308522 0 0 790728 0 1306349 0 0 0 0 1072723 0 0 190355 306056 247961 0 0 0 0 0 0 0 179793 437613 0 0 117904 1459182 0 0 0 0 1722660 0 0 0 0 1046747 0 0 0 0 144817 0 0 0 0 315691 0 0 358547 309666 589292 0 0 0 0 0 0 0 415327 582671 0 0 214339 767365 0 0 0 0 786290 0 0 0 0 635178 0 0 530770 0 435501 0 0 0 0 558931 0 0 259330 187926 0 0 0 0 0 0 0 0 86162 386055 0 0 93690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFIEPTYTDDHKEVFR MGYG000000243_00625 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0436@1|root,COG0436@2|Bacteria,4PNG6@976|Bacteroidetes,2G0SS@200643|Bacteroidia,4AVDR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1200017 0 0 0 0 0 648353 0 0 0 0 0 0 643494 0 508553 0 0 0 0 602446 0 0 0 0 759309 0 0 0 0 1777651 0 0 0 0 1096268 0 0 303212 0 0 0 0 0 449218 0 0 0 0 0 0 569312 0 69339 0 0 0 0 88845 0 0 0 0 164493 0 0 0 0 238857 0 0 0 0 420892 0 0 486214 0 0 0 0 0 463585 0 0 0 0 0 0 764820 0 1084765 0 0 0 0 1148009 0 0 0 0 851040 0 0 0 0 342658 0 0 0 0 570061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFILPK MGYG000000042_00112;MGYG000003351_02824;MGYG000000013_01592;MGYG000001345_00708;MGYG000003363_00794;MGYG000001364_03030;MGYG000001337_03360;MGYG000000273_00592;MGYG000000243_03061;MGYG000001313_02816;MGYG000001306_02021;MGYG000004876_02630;MGYG000001469_02540;MGYG000000098_03289;MGYG000002218_02429;MGYG000000236_02271;MGYG000003922_03784;MGYG000002455_01260;MGYG000000196_02850;MGYG000004797_00528;MGYG000004748_01740;MGYG000002614_00510;MGYG000000105_02714;MGYG000002540_02630;MGYG000001783_00321;MGYG000003681_00501;MGYG000001750_00812;MGYG000004899_03438;MGYG000001378_01736;MGYG000000127_02932;MGYG000002171_03034;MGYG000001780_02719;MGYG000001925_00352 domain d__Bacteria 1.0 COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,2FMPF@200643|Bacteroidia,4AMNF@815|Bacteroidaceae 0.8787878787878788 976|Bacteroidetes 0.9393939393939394 L 0.9393939393939394 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria 0.9393939393939394 dnaN 0.9393939393939394 - 1.0 2.7.7.7 0.9393939393939394 ko:K02338 0.9393939393939394 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 0.9393939393939394 M00260 0.9393939393939394 R00375,R00376,R00377,R00378 0.9393939393939394 RC02795 0.9393939393939394 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 0.9393939393939394 - 1.0 - 1.0 - 1.0 DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 0.9393939393939394 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed DNA polymerase. DNA nucleotidyltransferase (DNA-directed). Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.-!-Cannot initiate a chain de novo.-!-Requires a primer which may be DNA or RNA.-!-See also EC 2.7.7.49. a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1). 0.9393939393939394 0.9393939393939394 0.9393939393939394 0.9393939393939394 Homologous recombination;Metabolic pathways;Mismatch repair;Purine metabolism;DNA replication;Pyrimidine metabolism 0.9393939393939394 none 1.0 0 0 3216895 2529619 2659441 2375500 2771207 2234658 2329774 1997139 2408757 2074320 0 0 1790508 0 2580567 1489604 2048113 2174816 2480994 2303758 2171905 3132941 0 2228882 0 1718978 2339593 2372742 3427451 0 3717031 2425745 0 2648026 2413846 3757366 2492462 0 2639721 2690107 2425566 2212189 2177732 2846194 2923082 2888717 3273635 2770362 0 0 3066629 2476755 2731968 1828974 2592856 2377085 2666939 2436869 3178964 1800147 0 2807627 0 2447473 2081554 2642712 1420630 0 2486935 2378659 2819942 2504566 2744743 2651221 2340566 0 2753783 2493791 3785255 3038159 3413086 2206059 3094661 2201113 3003701 3412057 0 0 2175435 2613345 2572734 4648178 2376541 2253237 2480251 1901691 3939977 3500602 0 2521699 0 3241232 2979790 2536255 3254986 0 1979599 1820479 2585435 2806444 2498222 2541637 1479597 0 1356961 1270590 0 0 1620898 1779392 1259623 1367699 1388259 1727941 0 0 1451589 0 1225952 1451947 1414648 994521 1448180 0 1999576 1138348 0 1425126 0 723633 1286093 1230182 1147266 0 1304524 1982381 1713688 2009545 1578260 1031949 1743824 0 1366846 1903023 2909568 2461685 1975251 2311661 2173788 1501902 1938292 1545978 0 0 1605564 1971624 1943617 4019593 1428950 2301696 1303880 2202152 3837636 2981090 0 1496273 0 3085999 1988478 0 1663053 0 945079 2430614 2171471 1493115 1861265 1562717 -AAFK(Lys->Asn)TNFQER MGYG000004797_01285 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia,22W91@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 CarboxypepD_reg-like domain 1.0 susC 1.0 - 1.0 - 1.0 ko:K21573 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14.6.1 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1561630 0 0 0 0 0 0 0 0 0 579179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 627838 0 0 0 0 762347 0 0 0 0 329056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4027979 0 0 0 0 3019767 0 0 0 0 2014517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFKTDNPIEEMGIK MGYG000001346_02121;MGYG000004876_03122;MGYG000004797_02542 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,2FN08@200643|Bacteroidia,4AM9Z@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 2-oxoacid acceptor oxidoreductase, alpha subunit 1.0 porA 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00174 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFOR_II,POR,POR_N,Transketolase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 123088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 555768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFLGSEDAQLAHFK MGYG000002492_00484 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC transporter, solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1376220 0 0 0 0 852263 0 0 0 0 763976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFLLPK MGYG000000236_02271;MGYG000003351_02824;MGYG000000013_01592;MGYG000002455_01260;MGYG000000196_02850;MGYG000004756_00320;MGYG000004797_00528;MGYG000001372_00582;MGYG000003367_02648;MGYG000001345_00708;MGYG000001783_00321;MGYG000001388_00629;MGYG000003363_00794;MGYG000001337_03360;MGYG000000243_03061;MGYG000004876_02630;MGYG000001469_02540;MGYG000001835_01004;MGYG000001370_00874;MGYG000000127_02932 domain d__Bacteria 1.0 COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,2FMPF@200643|Bacteroidia,4AMNF@815|Bacteroidaceae 0.75 976|Bacteroidetes 0.85 L 0.85 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria 0.85 dnaN 0.85 - 1.0 2.7.7.7 0.85 ko:K02338 0.85 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 0.85 M00260 0.85 R00375,R00376,R00377,R00378 0.85 RC02795 0.85 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 0.85 - 0.95 - 1.0 - 1.0 DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 0.85 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed DNA polymerase. DNA nucleotidyltransferase (DNA-directed). Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.-!-Cannot initiate a chain de novo.-!-Requires a primer which may be DNA or RNA.-!-See also EC 2.7.7.49. a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1). 0.85 0.85 0.85 0.85 Homologous recombination;Metabolic pathways;Mismatch repair;Purine metabolism;DNA replication;Pyrimidine metabolism 0.85 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2375961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFM(Oxidation)PQAEK MGYG000002223_00929;MGYG000001300_00132;MGYG000002641_00308 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 596368 0 467737 417867 0 0 313134 0 303102 0 0 0 0 0 0 0 0 0 594251 0 0 0 0 0 233075 363725 0 0 0 0 0 0 578872 0 0 0 366275 533039 511878 0 681403 613422 0 0 1013846 0 1833916 0 0 565099 0 0 0 0 0 0 899616 0 0 0 0 0 846687 671278 0 0 0 0 0 0 733608 0 0 0 975171 863573 249544 0 0 127862 0 0 484707 0 394155 0 0 0 0 0 0 0 0 0 119508 0 0 0 0 0 161380 0 0 0 0 0 0 0 0 0 0 0 0 0 731075 0 822549 578853 0 0 1012312 0 733270 0 0 1040163 0 0 0 0 0 0 839307 0 0 0 0 0 653103 482778 0 0 0 0 0 0 812399 0 0 0 574062 427691 0 0 157481 0 0 0 0 0 405240 0 0 488092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFMPQAEK MGYG000002223_00929;MGYG000001300_00132;MGYG000002641_00308 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 3264509 3462708 4500167 4478205 626089 2827178 2924233 2223521 3516126 2864494 1593632 838444 2630783 3993072 1969267 2121644 3167593 1116862 4152876 3915264 603258 2455894 1025826 4068618 3168196 3372417 3155947 881731 0 282974 3507532 2372453 4044308 4878050 1605254 3072201 2784912 3992104 8103806 6621774 7507742 7965971 4722833 6083891 9852114 4165962 7828478 1007258 3158181 5840124 4643619 10240420 6886608 4330804 9581990 1741039 10763512 8269484 2760117 3663877 1537657 5447261 9177536 8179371 6947374 1668610 0 4755969 5633448 5104243 7840851 7697897 4045749 7331537 7831108 5869988 1546184 1140062 847476 1923541 988583 0 2260309 735193 1124820 682870 1391490 737329 1820307 2102474 1047280 851639 591471 749806 608857 1095983 465228 780695 715616 433325 625475 1235940 785205 936456 0 335028 1164215 943337 666986 1918494 218506 1262792 1121326 619813 3195668 3164704 4224682 3631126 3624367 5360920 5963204 2682589 3935452 3913583 3601302 5047180 4994172 3717361 3652508 3776451 3255896 1343503 4373369 3394048 3511305 4863248 1556695 4158738 3802312 3877750 3228584 1585177 0 4370331 4587132 3204446 4552535 5272204 1839031 3035387 3579500 4204917 0 207118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119418 0 0 0 878441 0 0 0 0 265063 0 0 0 0 0 0 0 0 0 0 -AAFNAQATK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 815268 0 169707 445556 257096 229097 0 231878 271322 309920 0 87381 0 506467 229900 408491 0 0 310820 735041 544799 431194 0 269035 0 533423 510833 0 522200 335247 0 0 0 495298 665027 549356 534167 674017 9087969 3817244 6102920 9342143 4653224 3261455 0 7463001 8338944 7896838 4299447 6607375 0 8444132 9294820 3523712 0 0 7631843 8119398 6278260 2934013 0 3255589 6897405 9239609 7848244 0 6297051 5767283 0 4490819 5758911 7137573 6234869 7714426 8602223 4318666 324004 0 0 0 0 0 0 0 1046773 0 153418 97932 0 286744 551470 0 0 0 960350 0 533872 0 0 679783 0 393738 500564 0 0 0 0 0 0 0 0 0 0 535440 1960639 711318 1765925 1470708 860531 0 0 1793541 1142261 1759603 662076 1562547 0 1117724 2154557 988191 0 0 1640487 1301066 1103856 0 0 0 1754169 2241902 1472255 0 1322969 1681579 0 1290896 1761000 0 2546416 1980733 1915197 787820 0 668652 0 0 959584 757578 0 551310 595158 589617 70554 545514 0 483662 885503 651498 0 0 653014 1157985 411353 319209 0 358566 976498 832254 643719 0 1095951 278392 0 405254 236923 0 302445 965623 0 0 -AAFNDFSK MGYG000002494_04635 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,3XN5M@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 M 1.0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery 1.0 bamD 1.0 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 1.0 - 1.0 ko:K05807 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.33.1 1.0 - 1.0 - 1.0 TPR_18,TPR_6,YfiO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1160777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1256097 0 1135882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFPEKTFGEEMKPGTLGFGSTIFAVKPGDGSAR MGYG000002517_03119 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 aconitate hydratase 1.0 ybhJ 1.0 - 1.0 4.2.1.3 1.0 ko:K01681 1.0 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 1.0 M00009,M00010,M00012,M00173,M00740 1.0 R01324,R01325,R01900 1.0 RC00497,RC00498,RC00618 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aconitase,Aconitase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aconitate hydratase. citrate hydro-lyase. Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate.-!-The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate.-!-cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate.-!-Formerly EC 4.2.1.4. citrate = D-threo-isocitrate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Citrate cycle (TCA cycle);Glyoxylate and dicarboxylate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFPIIK MGYG000001164_02228 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella lascolaii|m__MGYG000001164 1.0 COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,2FP6Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Succinate dehydrogenase Fumarate reductase 1.0 frdB 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00240 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer2_3,Fer4_7,Fer4_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1246400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFPLEWLHDSK MGYG000002438_02897 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,2FKZJ@200643|Bacteroidia,22W2V@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the GcvP family 1.0 gcvP 1.0 - 1.0 1.4.4.2 1.0 ko:K00281,ko:K00283 1.0 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 1.0 M00532 1.0 R01221,R03425 1.0 RC00022,RC00929,RC02834,RC02880 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5,GDC-P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine dehydrogenase (aminomethyl-transferring). glycine dehydrogenase (decarboxylating). A component of the glycine cleavage system, which is composed of four components that only loosely associate: the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H protein.-!-Previously known as glycine synthase. glycine + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] = CO2 + N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl- [glycine-cleavage complex H protein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223118 0 0 0 75918 0 0 0 0 261551 0 0 0 0 0 0 0 0 188046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 48200 0 0 0 0 0 0 0 0 125553 0 0 0 0 0 0 0 0 56605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 43304 0 0 0 71995 0 0 0 0 179354 0 0 0 0 0 0 0 0 51859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256721 0 0 0 237374 0 0 0 0 447150 0 0 0 0 0 0 0 0 347728 0 0 0 0 0 0 0 0 -AAFPLSLSQEAQIAQSR MGYG000002494_04631 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,3XMUR@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) 1.0 aroF 1.0 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 2.5.1.54 1.0 ko:K01626 1.0 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 1.0 M00022 1.0 R01826 1.0 RC00435 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_3932,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iLF82_1304.LF82_0146,iNRG857_1313.NRG857_03335,iSbBS512_1146.SbBS512_E1908,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934 1.0 DAHP_synth_1,P22_Cro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-deoxy-7-phosphoheptulonate synthase. phospho-2-oxo-3-deoxyheptonate aldolase. Formerly EC 4.1.2.15. D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2- dehydro-3-deoxy-D-arabino-heptonate + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Phenylalanine, tyrosine and tryptophan biosynthesis;Biosynthesis of secondary metabolites;Quorum sensing;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232836 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579796 0 0 0 0 644780 1027362 0 1009410 0 0 0 1413096 0 756874 1553429 0 0 0 1502449 0 0 1920627 0 825216 0 2055159 0 0 0 1457073 945487 0 0 2300342 2145598 0 0 1164539 686706 0 931707 597460 695724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158844 157915 0 0 0 0 0 0 0 100563 0 85468 70098 62013 -AAFPQVDVVVGNVATGEAAK MGYG000002293_02133;MGYG000003697_01312 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,2FMKX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO,NanE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 578342 0 0 0 0 521075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 664730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766663 0 0 0 0 1712952 0 0 0 0 0 0 0 0 0 404000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFQA(Ala->Thr)EDVVSSHEKK MGYG000000133_01247 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3XZ6B@572511|Blautia 1.0 186801|Clostridia 1.0 P 1.0 Psort location CytoplasmicMembrane, score 1.0 actP 1.0 - 1.0 3.6.3.4,3.6.3.54 1.0 ko:K01533,ko:K17686 1.0 ko01524,ko04016,map01524,map04016 1.0 - 1.0 R00086 1.0 RC00002 1.0 ko00000,ko00001,ko01000 1.0 3.A.3.5 1.0 - 1.0 - 1.0 E1-E2_ATPase,HMA,Hydrolase,YHS 1.0 - 1.0 - 1.0 - 1.0 CBM50 1.0 P-type Cu(2+) transporter. | P-type Cu(+) transporter. Cu(2+)-exporting ATPase. | Cu(+)-exporting ATPase. A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.-!-The enzyme from the termophilic bacterium Archaeoglobus fulgidus is involved in copper extrusion from the cell.-!-Formerly EC 3.6.3.4. | A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.-!-This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 7.2.2.9, which mainly transports the divalent copper ion.-!-Formerly EC 3.6.3.54 and EC 3.6.3.n1. ATP + Cu(2+)(in) + H2O = ADP + Cu(2+)(out) + H(+) + phosphate. | ATP + Cu(+)(in) + H2O = ADP + Cu(+)(out) + H(+) + phosphate. 1.0 1.0 1.0 1.0 Platinum drug resistance;MAPK signaling pathway - plant 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1068015 0 0 0 0 0 0 -AAFSAIPGVEVR MGYG000001300_00512 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 622878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1595232 0 0 0 0 1884434 0 0 0 0 930221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFSNDMVYMEK MGYG000002506_02896;MGYG000002477_00118;MGYG000002494_01866;MGYG000002534_00468 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,3XP5G@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 I 1.0 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA 1.0 accC 1.0 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 1.0 6.3.4.14,6.4.1.2 1.0 ko:K01961 1.0 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 1.0 M00082,M00376 1.0 R00742,R04385 1.0 RC00040,RC00253,RC00367 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iSF_1195.SF3294 1.0 Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 biotin carboxylase. | acetyl-CoA carboxylase. - This enzyme, part of an acetyl-CoA carboxylase complex, acts on a biotin carboxyl-carrier protein (BCCP) that has been biotinylated by EC 6.3.4.15.-!-In some organisms the enzyme is part of a multi-domain polypeptide that also includes the carrier protein (e.g. mycobacteria).-!-Yet in other organisms (e.g. mammals) this activity is included in a single polypeptide that also catalyzes the transfer of the carboxyl group from biotin to acetyl-CoA (see EC 6.4.1.2). | This enzyme is a multi-domain polypeptide that catalyzes three different activities - a biotin carboxyl-carrier protein (BCCP), a biotin carboxylase that catalyzes the transfer of a carboxyl group from hydrogencarbonate to the biotin molecule carried by the carrier protein, and the transfer of the carboxyl group from biotin to acetyl-CoA, forming malonyl-CoA.-!-In some organisms these activities are catalyzed by separate enzymes (see EC 6.3.4.14 and EC 2.1.3.15).-!-The carboxylation of the carrier protein requires ATP, while the transfer of the carboxyl group to acetyl-CoA does not. ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate. | acetyl-CoA + ATP + hydrogencarbonate = ADP + H(+) + malonyl-CoA + phosphate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Fatty acid metabolism;Fatty acid biosynthesis;Carbon fixation pathways in prokaryotes;Metabolic pathways;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 215196 0 0 403281 0 0 0 386546 0 0 0 0 0 0 0 0 0 0 0 354381 0 480749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754593 0 0 1697935 0 0 0 1078183 0 0 0 0 0 0 1070602 0 951733 0 0 1955228 0 1333992 0 0 0 0 0 0 0 0 791707 0 0 0 0 766944 0 0 209262 0 0 515817 0 0 0 339214 0 0 0 0 0 0 0 0 254890 0 0 638115 0 482478 0 0 0 0 0 0 0 0 340900 0 0 0 0 306372 0 0 0 0 0 563584 0 0 0 512158 0 0 0 0 0 0 288574 0 0 0 0 383301 0 303033 0 0 0 0 0 0 0 0 411971 0 0 0 0 144028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFTADSK MGYG000000077_00225;MGYG000000262_01201 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,25WFS@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 E 1.0 Periplasmic binding protein 1.0 braC 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1737441 0 0 0 0 0 0 0 0 0 0 0 0 2902728 0 0 0 0 0 0 0 0 0 0 3081290 0 0 0 0 0 0 1992355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1446363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1363680 0 0 905322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 950256 0 0 0 0 0 0 -AAFTADSKTDFGTQLQK MGYG000000262_01201 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,25WFS@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 E 1.0 Periplasmic binding protein 1.0 braC 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFVLDAIR MGYG000000028_01617;MGYG000002528_01844 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,2680N@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 1.0 rpsC 1.0 - 1.0 - 1.0 ko:K02982 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 149473 502030 393525 0 228028 920832 0 0 0 183200 463324 0 173405 0 196264 0 261856 0 163412 118991 353297 723157 0 202624 79626 0 0 0 517508 218824 121735 361317 0 0 0 0 0 0 298842 1193167 473750 0 464142 1159230 219588 285667 213989 267423 213617 0 356457 205703 292615 0 393388 0 271086 286772 168388 534097 0 1452890 107228 261299 344706 0 621536 0 902335 1079024 452295 188625 438163 345732 294170 483256 1389340 3983048 1831542 0 880834 3119252 1560621 1567133 1264864 1383874 1405977 0 1165426 1673456 1404551 0 2271893 0 1615388 1392917 1259869 7716418 0 2882942 1662590 1441524 1701242 0 4462076 1198979 1292828 4354011 1952541 2493402 1135412 1204075 1051218 1679565 163367 728148 342246 0 501751 280671 207401 257535 93988 331231 377626 0 206308 219097 245463 0 227909 0 294753 147509 264590 529899 0 470681 0 0 311519 0 1620492 243693 540327 0 463753 0 231858 420815 201728 381758 0 0 0 0 0 0 163344 0 0 0 0 0 201022 0 0 0 0 0 0 0 0 0 0 0 0 72340 0 0 0 0 0 0 111091 0 0 0 0 0 -AAFVTK MGYG000001338_01027;MGYG000000142_03199;MGYG000000233_01112 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 9.98 0.6666666666666666 metY 1.0 - 1.0 2.5.1.49 1.0 ko:K01740 1.0 ko00270,ko01100,map00270,map01100 1.0 - 1.0 R01287,R04859 1.0 RC00020,RC02821,RC02848 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 209825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 129782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 716328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFYEDLK MGYG000000196_04104;MGYG000001345_01383;MGYG000001378_03183 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG5523@1|root,COG5523@2|Bacteria,4NTWR@976|Bacteroidetes,2FRNK@200643|Bacteroidia,4AMPR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Protein of unknown function (DUF975) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF975 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1695888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 677102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 722687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAFYFDK MGYG000000003_01804;MGYG000003279_01060 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,2FM6J@200643|Bacteroidia,4AMTF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_2,SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1009934 1272765 517561 1004778 673205 1160165 694233 0 1025972 1408823 407991 1676300 747068 1052595 1655573 808717 1357050 0 1112217 1076509 1646418 908034 0 1449627 1186581 1377697 1660089 0 921969 2100800 886050 1156165 756558 0 898549 1293731 1436986 411612 0 0 0 0 0 110930 0 0 0 79623 0 0 0 63268 0 81162 0 0 0 98099 0 0 0 159662 0 0 0 0 0 0 0 0 125359 0 0 0 0 0 2322264 770804 1666197 1566762 1590414 671224 1755065 0 2057640 1502708 985001 1763717 850165 1943646 1793599 816058 1476474 0 1378593 2057436 2262282 634656 0 928866 1700064 1555539 1437865 0 1449167 2397535 954847 605972 1179690 2315974 1333461 2515541 1679176 1661488 274793 130167 196661 258762 287535 131677 246458 0 421955 333339 101819 272780 365665 366295 417693 134093 223753 0 373144 291354 281981 247998 0 240874 365385 353668 187610 0 225429 137285 305412 262153 471496 346120 349128 331314 318078 243140 0 0 0 0 0 0 0 0 94017 0 0 0 0 85852 114666 0 0 0 92436 117606 0 107934 0 132893 0 0 76235 0 94107 0 0 0 0 0 0 75905 0 0 -AAFYFDKVK MGYG000000003_01804;MGYG000003279_01060 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,2FM6J@200643|Bacteroidia,4AMTF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_2,SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 780374 1271397 504622 1021831 802075 1181706 718904 115963 1029380 1351217 737193 1113513 823228 890720 1072577 828514 1537178 0 978515 974011 988062 989092 0 669633 1054511 830415 943101 0 854679 1485970 742991 1056884 702621 623471 543197 1260573 1126897 645617 0 0 0 0 0 0 0 0 0 0 0 0 127186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 580679 789148 446563 661875 795279 502873 317618 641603 600899 960715 561555 527967 771467 505472 641273 700415 275770 526681 0 537914 804412 898212 380766 0 388663 753968 654522 508892 0 601959 1122361 338078 78647 459368 844256 484635 1016545 543465 522011 96213 781458 91601 47277 508450 54539 366412 74604 45826 95549 61194 74733 498748 62960 90815 60827 78958 0 61108 372524 152307 147440 0 616270 149909 370194 446992 0 3002413 58456 180178 99835 56501 84010 419378 87398 146615 63881 377750 0 218332 0 0 0 0 227547 242848 0 0 294351 141661 122595 0 197442 168653 0 0 60888 0 0 0 0 0 225671 693060 0 0 116399 0 0 411458 0 37249 112390 110436 0 -AAFYIFPK MGYG000004697_00512;MGYG000002978_00471;MGYG000003266_00674;MGYG000002528_00752;MGYG000004716_00719;MGYG000004879_01333;MGYG000003683_00468;MGYG000000262_02327;MGYG000001567_00684;MGYG000003452_00958;MGYG000002492_01227;MGYG000002396_01232 domain d__Bacteria 1.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WHR7@541000|Ruminococcaceae 0.3333333333333333 186801|Clostridia 0.3333333333333333 E 0.9166666666666666 Aminotransferase class I and II 0.3333333333333333 - 0.75 - 0.75 2.6.1.2,2.6.1.66 0.6666666666666666 ko:K14260 0.6666666666666666 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 0.6666666666666666 - 0.8333333333333334 R00258,R01215 0.6666666666666666 RC00006,RC00008,RC00036 0.9166666666666666 ko00000,ko00001,ko01000,ko01007 0.75 - 1.0 - 0.9166666666666666 - 0.75 Aminotran_1_2,HTH_19,HTH_3,HTH_31 0.5 - 1.0 - 1.0 - 1.0 - 1.0 alanine transaminase. | valine--pyruvate transaminase. glutamic--pyruvic transaminase. | valine--pyruvate aminotransferase. 2-aminobutanoate acts slowly instead of alanine. | Different from EC 2.6.1.42. 2-oxoglutarate + L-alanine = L-glutamate + pyruvate. | L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Alanine, aspartate and glutamate metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 0.6666666666666666 none 1.0 0 0 408146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397433 0 0 0 237016 406767 0 0 0 108380 0 0 79781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140035 0 0 0 361924 219533 0 0 0 223543 0 0 561664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467074 0 0 0 589851 367700 0 0 0 574547 0 0 207185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025876 0 0 0 172429 0 0 0 0 229913 0 0 288195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466757 0 0 0 638807 307774 0 0 0 345334 -AAFYLFPK MGYG000002978_00471;MGYG000002528_00752;MGYG000002919_00495;MGYG000003683_00468;MGYG000000262_02327;MGYG000001698_00697;MGYG000003063_03201;MGYG000002492_01227 domain d__Bacteria 1.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WHR7@541000|Ruminococcaceae 0.375 186801|Clostridia 0.5 E 0.875 Aminotransferase class I and II 0.375 - 0.875 - 0.875 2.6.1.2,2.6.1.66 0.75 ko:K14260 0.75 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 0.75 - 0.875 R00258,R01215 0.75 RC00006,RC00008,RC00036 0.875 ko00000,ko00001,ko01000,ko01007 0.75 - 1.0 - 0.875 - 0.875 Aminotran_1_2,HTH_3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 alanine transaminase. | valine--pyruvate transaminase. glutamic--pyruvic transaminase. | valine--pyruvate aminotransferase. 2-aminobutanoate acts slowly instead of alanine. | Different from EC 2.6.1.42. 2-oxoglutarate + L-alanine = L-glutamate + pyruvate. | L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine. 0.75 0.75 0.75 0.75 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Alanine, aspartate and glutamate metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277598 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAG(Gly->Asp)GVILITTK MGYG000002438_00861;MGYG000002218_02008;MGYG000000355_00074;MGYG000002478_00138;MGYG000002834_00163;MGYG000001489_04986;MGYG000003521_00292;MGYG000001666_00694;MGYG000003697_02612;MGYG000002080_00857 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 0.4 976|Bacteroidetes 1.0 P 0.9 TonB-linked outer membrane protein, SusC RagA family 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1885778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1491356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAG(Gly->Glu)ELGLTTK MGYG000000164_01271 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,25UR1@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 FGGY family of carbohydrate kinases, N-terminal domain 1.0 - 1.0 - 1.0 2.7.1.17 1.0 ko:K00854 1.0 ko00040,ko01100,map00040,map01100 1.0 M00014 1.0 R01639 1.0 RC00002,RC00538 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 xylulokinase. Xylulose kinase. - ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+). 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions;Metabolic pathways 1.0 none 1.0 2780663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3377624 0 0 0 0 3881725 3128101 0 0 0 0 0 0 0 0 3127461 0 2973362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300913 0 0 0 0 0 0 0 0 0 0 0 0 0 354343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288094 0 0 0 0 301082 212431 0 0 0 0 0 0 0 0 187305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 487071 0 0 0 0 0 530465 0 0 0 0 0 0 0 0 0 0 827428 0 -AAG(Gly->Tyr)GVILITTK MGYG000002438_00861;MGYG000002218_02008;MGYG000000355_00074;MGYG000002478_00138;MGYG000002834_00163;MGYG000001489_04986;MGYG000003521_00292;MGYG000001666_00694;MGYG000003697_02612;MGYG000002080_00857 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 0.4 976|Bacteroidetes 1.0 P 0.9 TonB-linked outer membrane protein, SusC RagA family 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2501993 2728519 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAAAAAEEEKTEFDVILAEAGATK MGYG000001300_02635 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1603812 0 302946 0 0 9772409 333498 0 0 0 0 0 0 0 0 0 6677504 0 0 0 0 272561 0 275107 0 326991 0 0 0 0 0 0 3395064 0 0 0 302767 18566505 6870188 0 5985027 0 0 18133767 28677490 0 0 0 0 0 0 0 0 0 17313186 0 0 0 0 0 0 7734150 0 10118 0 0 0 0 0 0 8785166 0 0 0 0 179330 152316 0 79069 0 0 0 2681973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133887 0 8048956 0 0 0 0 0 0 0 0 339637 0 0 0 1697732 2601086 8539829 0 30136612 0 0 35959800 22812816 0 0 0 0 0 0 0 0 0 16356977 0 0 0 0 20436628 0 12253603 0 11254315 0 0 0 0 0 0 7186562 0 0 0 10789660 17736993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7625295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAAAALLK MGYG000001617_02059 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp900547735|m__MGYG000001617 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,21XZX@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Formyltetrahydrofolate synthetase 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAAAPAEEEKTEFDVILADVGANK MGYG000004866_01000;MGYG000000084_00772 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 8838716 0 0 0 0 0 0 0 0 0 0 2546151 0 0 0 0 1255022 0 0 0 0 3347665 0 0 5615346 0 0 0 0 0 0 0 0 0 0 0 0 0 3856452 0 0 0 0 0 0 0 0 0 0 10741630 0 0 0 0 4987639 0 0 0 0 8057083 0 0 2844943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5206484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238059 0 0 0 0 9670143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24636388 0 0 0 0 0 0 0 0 0 0 13173476 0 0 0 0 8188736 0 0 0 0 0 0 0 2081578 0 0 0 0 0 0 0 -AAGAADMSC(Carbamidomethyl)DAANVR MGYG000001300_00243 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 434146 454934 0 0 0 0 498991 0 0 0 0 0 0 0 0 0 516103 0 0 147136 0 289367 0 0 0 0 0 0 0 0 0 465488 0 0 0 0 0 0 477671 606740 0 504085 544869 0 600919 0 0 0 0 0 0 0 0 0 653506 0 0 390630 0 350010 0 0 0 0 0 0 0 0 528775 658577 0 0 0 350421 0 0 0 0 0 0 191785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312254 676926 0 754667 717809 0 928419 0 0 0 0 0 0 0 0 0 738532 0 0 519932 0 321297 0 0 0 0 0 0 0 0 603457 1218390 0 0 0 486031 0 0 0 0 0 0 489995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642018 619851 0 0 0 497124 -AAGAAEAAEEKDEFDVELAEVGPNK MGYG000001338_03386 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3XZZA@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294038 0 0 0 0 0 0 0 0 713053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 701460 0 0 0 0 0 0 0 0 480861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296349 0 0 0 0 0 0 0 0 376851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309243 0 0 0 0 0 0 0 0 845831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450745 0 0 0 0 0 0 0 -AAGAAEAAEEKDEFDVELAEVGPNKVK MGYG000001338_03386 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3XZZA@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 281342 0 0 782052 0 0 0 0 0 159606 0 242989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318346 1052443 0 0 0 0 0 0 0 562243 0 0 294925 0 0 0 0 0 191931 0 147510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 614521 201974 0 0 0 0 0 0 0 1343923 0 0 280525 0 0 0 0 0 279606 0 369716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550024 1073646 0 0 0 0 0 0 0 1350405 0 0 621426 0 0 0 0 0 685548 0 667235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 903409 778910 0 0 0 0 0 0 0 1352010 0 0 786961 0 0 0 0 0 505405 0 1284642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1113350 1939490 0 0 0 0 0 0 -AAGAAEAAEEKTEFDVELTEVGPNKVK MGYG000002445_02302 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp003024715|m__MGYG000002445 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAAGEAAEEKDEFDVELTEVGPNKVK MGYG000000301_02336 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900541985|m__MGYG000000301 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3XZZA@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAAGVIRPD(Asp->Ser) MGYG000000039_00617 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_H|m__MGYG000000039 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 1.0 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Phosphotransferase system (PTS) 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 595875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4585350 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAAGVIRPDK MGYG000000022_01527;MGYG000000195_02492;MGYG000002274_00521 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 1.0 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Phosphotransferase system (PTS) 1.0 none 1.0 153898 0 0 0 140299 90715 234654 106355 0 79508 0 117281 0 123294 60870 144155 0 496829 0 0 115901 0 273441 154299 0 116570 0 406292 91711 94842 82579 0 153850 128235 130472 161625 0 0 605982 0 594633 0 360772 680316 217490 360620 582179 380732 0 361893 327229 549507 174538 295934 370445 3516720 0 0 214731 384762 3547292 193423 204160 313684 588846 3480070 363256 384058 240864 805486 773430 575190 517917 439532 481433 806725 1073319 0 780932 0 1086732 1195773 1321744 894640 980009 1225708 0 679372 758385 1183082 1172064 725020 1118275 3051828 0 0 762876 958575 3463698 1292128 1055055 898758 813118 3593247 1192374 1220648 978932 821241 723441 862431 941536 991898 835925 964340 0 0 0 0 0 152168 0 0 0 0 0 0 0 0 0 0 0 269769 0 0 232520 0 164115 134661 0 0 130577 330074 0 0 0 178341 0 84843 171217 163959 0 0 351499 0 492041 0 173877 307351 386572 493203 394551 353292 0 324532 339326 160942 320147 469412 324513 3807065 0 0 320630 432480 5113963 333095 259728 289391 259802 4747104 223715 186565 323387 286457 565240 363389 115973 477191 253970 409756 -AAGAAGVIRPDKTTC(Carbamidomethyl)QVIIGTK MGYG000000022_01527;MGYG000000195_02492 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 1.0 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Phosphotransferase system (PTS) 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212651 0 0 0 0 0 0 0 0 0 327233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 696691 0 0 0 0 570841 0 0 0 0 959801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 441170 0 0 0 0 970352 0 0 0 0 0 0 0 0 0 0 -AAGAAGVIRPGK MGYG000000140_01482 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UMGS1375|s__UMGS1375 sp900066615|m__MGYG000000140 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 1.0 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Phosphotransferase system (PTS) 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136787 0 0 0 0 244050 0 0 0 0 102357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2953495 0 0 0 0 2164232 0 0 0 0 2008074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAAGVIRPS MGYG000001300_00059;MGYG000003899_00538;MGYG000003921_01901;MGYG000002641_02329;MGYG000001157_01521;MGYG000003937_01168;MGYG000002610_01595;MGYG000004719_01899;MGYG000003166_01772;MGYG000000084_01199;MGYG000004732_01998 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 0.9090909090909091 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 0.9090909090909091 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Phosphotransferase system (PTS) 1.0 none 1.0 2562984 2959722 2983834 2551600 2352356 3301349 1965050 3352730 2607111 3088989 2866458 2602366 0 3874534 4280613 2886756 2631415 13603964 4290097 3947219 2655933 2955779 6753640 2092964 3350461 2741635 2067557 7305715 2642059 2000112 2194786 0 2587881 3216156 2508801 2171207 3005343 2756895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1313738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381207 50175 604184 0 0 0 0 239677 0 0 0 0 558277 0 0 0 0 0 0 0 0 0 0 2074236 2657416 2818185 2268786 2918094 3174568 2941389 1794172 2638176 3311361 2740871 3296159 0 2188076 2316286 3222425 2736865 8655014 2513323 2798002 1475581 3197203 0 3381830 2116492 1803176 2169890 11557797 3144425 2956911 4247541 0 3473314 1092301 1712767 1909533 2231561 4401159 0 0 0 0 0 0 0 0 0 0 0 0 0 50823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAAGVIRPSK MGYG000001300_00059;MGYG000003899_00538;MGYG000002641_02329;MGYG000002610_01595;MGYG000004719_01899;MGYG000003166_01772;MGYG000003921_01901;MGYG000001157_01521;MGYG000003937_01168;MGYG000000573_01714;MGYG000000589_01770;MGYG000000084_01199;MGYG000004732_01998 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 0.9230769230769231 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 0.9230769230769231 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Phosphotransferase system (PTS) 1.0 none 1.0 3038466 2578770 2320798 2402109 2202834 2726132 1885541 2625671 2155745 2557331 2028145 2356291 2633543 2021091 2220053 2731123 2295918 5345294 2085531 3138417 2659412 3229958 5476115 2171410 2850486 2291407 2276658 5204316 2897774 2565345 1504737 1587442 1975615 2388499 2732057 2050969 2024967 2342847 4769715 3514684 3312143 3884215 1987551 3951041 5304542 3022298 4825351 1213686 2398657 5263918 2716606 3938169 3725097 2453877 3853542 6572083 4880370 4583634 1797860 2688843 6754714 3539759 4625681 3312511 3326005 7128486 1269805 3028442 2991218 2185287 2985830 3925091 2317380 3728832 4682351 3045111 1697732 1521950 1584076 1760475 1453714 1482305 2077184 1474172 1311780 1475684 1776183 1943178 2223627 1709399 1597279 1711847 1478694 5562223 1493944 1656761 701372 1601075 5286905 1428029 1611113 1828197 1388687 4981754 1267774 2097856 1747146 1499609 1438019 1920502 1652060 1432108 1065968 1606331 1036008 733241 1229253 931163 1073148 778724 714988 993409 619749 1043385 936185 2080535 1388235 684444 879099 809543 1065991 2428078 773469 614957 759390 972298 987791 888465 956837 784492 794806 1837278 1120816 1130971 1408191 852450 1289181 981914 874023 889730 915558 1183571 954565 1515163 1302168 1166350 827908 898748 713018 1382741 885577 1029472 920819 4878866 728001 1146698 968403 1073812 1051221 4489404 911690 722452 872011 658004 8133682 994548 1245189 1044993 761664 5487197 963469 1584675 1276135 1068310 984277 911402 904357 1520899 800945 910876 -AAGAAIGSSRPVAETLK MGYG000002143_01991;MGYG000001300_02302;MGYG000002720_01991;MGYG000002794_01678;MGYG000000195_01164;MGYG000000233_00728;MGYG000002272_02642;MGYG000002274_01133;MGYG000002445_01436;MGYG000002545_00762;MGYG000003899_01296;MGYG000000255_01766;MGYG000002720_01954 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WRQF@541000|Ruminococcaceae 0.9230769230769231 186801|Clostridia 1.0 C 0.9230769230769231 Acyl-CoA dehydrogenase, C-terminal domain 0.9230769230769231 bcd2 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha,Rubredoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 928850 0 680185 983381 0 0 771198 0 0 0 0 597064 0 0 865599 788369 0 829711 737307 1423817 853564 544972 0 795596 1020910 0 0 0 0 0 742000 0 0 0 0 0 0 0 1191772 0 626530 1126858 0 0 919271 0 0 0 0 813945 0 0 0 893567 0 747717 494836 1315075 0 815265 0 0 1134528 0 0 0 0 0 1192754 0 0 0 0 0 0 0 0 0 1136191 0 0 0 1150629 0 0 0 0 0 0 0 3019479 0 0 960969 922018 2983499 774498 1269994 0 0 3287935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135311 109064 0 0 0 0 0 0 0 353978 0 0 0 0 0 393493 0 268553 0 336960 0 226369 0 0 0 0 0 0 547336 0 0 0 0 0 0 0 0 0 98652 120914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92081 273023 0 0 0 0 0 0 0 0 0 0 141251 0 0 0 0 -AAGAAIGSSRPVAETLR(Arg->Lys) MGYG000002994_01166 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Megasphaeraceae|g__Megasphaera|s__Megasphaera sp002319965|m__MGYG000002994 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4H379@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha,Rubredoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 777885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAAPVAAAPAAPVAPK MGYG000001300_00242 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAAVVSTGR MGYG000004558_03069;MGYG000000184_01931;MGYG000003063_03282;MGYG000000251_00123;MGYG000000213_04019;MGYG000001338_00282;MGYG000000200_01241;MGYG000000002_01111;MGYG000004526_00006 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3XYME@572511|Blautia 0.8888888888888888 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 0.8888888888888888 - 1.0 - 1.0 1.1.1.38 1.0 ko:K00027 1.0 ko00620,ko01200,ko02020,map00620,map01200,map02020 1.0 - 1.0 R00214 1.0 RC00105 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 malate dehydrogenase (oxaloacetate-decarboxylating). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Two-component system 1.0 none 1.0 1116134 1948689 1384709 500636 2572278 909927 193247 1235928 0 1072034 2033354 1499707 2295452 903982 1067809 2078056 765552 2001662 0 1594560 0 1883083 1149551 402853 1158101 625829 694378 1545556 0 840312 563521 1610181 1070004 1036964 1167675 0 625694 1368650 2041947 5697628 956296 1365742 1772978 1194368 1296639 1987515 0 865466 1528003 1051539 1848722 1091417 1028406 935589 1013706 4649924 0 1782446 0 784204 3102076 1940159 969982 1181895 1800053 4249461 0 1063749 4334528 2396533 1082860 1644210 2161711 0 1497924 1211652 1875566 5809092 1864442 2157102 812688 1520373 1478515 2493430 0 2130781 1106626 1911232 2171289 1905032 2495159 2636870 1800190 1010403 0 2509502 0 2901234 2552505 1463300 2450978 1897487 2267792 3651856 0 2604603 1494688 2682611 2595389 3011670 2709885 0 1329575 1194379 1530597 2428903 2074249 1710616 3303947 1030736 1460861 1201194 0 1280881 1309425 2615548 2182714 866607 966392 2347258 1165105 1728445 0 1328470 0 2349450 645676 2224776 790742 929002 968490 2650214 0 1807355 3481317 2239698 2764988 730328 1401026 0 1050755 2589457 945988 3312351 2944762 1426563 610313 1054005 1083871 1460932 0 1151673 3138713 2602399 0 1921677 1364146 953823 967228 221236 0 363463 0 893184 1503517 1269561 1435363 1029566 949118 1395117 0 399740 2097996 1313278 4476092 1271134 1447752 0 1011962 2284489 -AAGAD(Asp->Ala)GAAAEEKTEFDVELTEVGPNKVK MGYG000002492_00338 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGADFVGAEDLIPK MGYG000000031_00709;MGYG000000002_03534;MGYG000004718_01623;MGYG000000142_01261;MGYG000000201_02339;MGYG000000205_00361 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 2096904 0 1121798 949431 0 1469785 0 0 0 0 2423882 0 0 0 0 0 2087307 0 0 0 1671346 1946313 0 0 2270702 0 0 0 0 0 0 0 1153441 0 2190646 0 0 597681 0 0 338758 0 0 399118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581915 0 0 0 0 0 0 0 0 369356 2154526 0 0 0 0 0 0 364735 0 0 1090041 0 0 418776 0 1072592 0 0 0 0 0 0 0 0 0 0 0 0 1018067 1524267 0 611747 1492548 0 0 0 0 1141536 0 0 2042313 1185787 1520994 0 0 0 1041707 0 0 673321 0 0 0 623715 0 0 0 0 0 0 0 0 0 0 0 0 1699061 0 0 0 0 0 0 0 0 2228266 0 0 0 0 528558 0 0 0 242997 0 0 0 0 894012 0 0 0 0 145325 0 0 0 0 0 0 0 0 0 0 692234 0 524016 114742 230921 0 0 0 0 0 0 599752 0 0 0 0 0 -AAGADFVGGDELIPK MGYG000000139_00679;MGYG000002772_00853;MGYG000000164_01129;MGYG000001374_02225;MGYG000000146_01144;MGYG000000249_00046;MGYG000000268_01636 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 0.7142857142857143 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1811669 1504386 740004 444670 1805116 2692767 2139323 1927430 2436599 2995725 1355023 0 2452051 1672510 2310564 0 1626560 473938 2014960 2202816 1985103 3262036 528886 1408162 0 1970623 0 0 2077844 0 814257 1302825 843216 1644256 1759297 1943731 1790585 784921 1695707 1549833 1685077 2036552 2046102 1375882 2415713 2274872 1487878 1512747 1572827 0 2806838 1706022 1281334 2067377 5124891 3134041 1818453 2269886 1513239 816685 1616681 1826534 0 1684374 0 2214780 2537584 0 2205547 2022945 1685112 1815972 2236320 1712035 1948958 1958361 1359373 1064318 0 977575 790368 663612 1058899 1277680 835225 1349983 963315 0 1513286 1216520 1242338 1317119 1344398 1058056 1129279 1421577 1261846 956422 1416383 838926 0 1498685 0 1679348 827929 0 858462 852435 1623923 1449785 1314875 783656 1449744 0 569765 721770 950046 476926 620148 612668 356662 829740 811046 841939 777235 0 1086253 700141 461964 952811 2638672 1311381 681238 720734 0 759923 766313 787645 0 461709 0 1746996 697948 0 564942 599292 1176812 400539 922085 425782 768954 440195 1430140 473877 369986 0 0 749210 0 500891 1215703 1121426 1075257 0 822201 238012 769363 850921 1241372 363168 429879 1491555 830381 677911 472007 996377 0 1346719 0 643853 271413 0 559806 0 300717 0 674284 851837 1253761 383716 -AAGADFVGGEDLIPK MGYG000001379_00716 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Schaedlerella|s__Schaedlerella glycyrrhizinilytica|m__MGYG000001379 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2173873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGADFVGGEELIPK MGYG000002992_01641;MGYG000001186_01608;MGYG000002279_01914;MGYG000000489_01684;MGYG000003149_00722;MGYG000001688_00640;MGYG000002670_00356;MGYG000000562_01874;MGYG000000136_02022;MGYG000000187_02021;MGYG000002492_00336;MGYG000001607_01030;MGYG000001319_01772 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 0.38461538461538464 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 1789608 1686642 0 1488028 0 670717 3144040 0 2061801 0 2187518 1549218 1529162 2332996 1665373 0 399236 2109444 2248454 0 0 491212 0 0 1858807 1652062 1235792 1719489 0 0 1471201 0 0 0 1433541 1375040 1306456 764813 599433 410185 0 415139 0 736931 617537 0 737683 0 246497 492257 676929 796538 0 0 439135 582303 1142665 401418 0 376910 0 0 894148 414338 243076 1250937 1613602 0 0 510236 0 633589 863078 1132014 425106 1527042 1495630 1036358 0 482035 0 691389 0 0 1141479 0 1244266 1057100 1015324 1303256 1620262 1017256 319504 1162054 2484133 1117621 0 371179 0 0 1137965 1697907 433745 1010685 0 0 1528726 1708619 0 1543052 920090 1112643 1282975 222762 359682 0 0 0 0 0 0 0 337325 0 230322 0 184655 250601 0 240458 512267 0 252583 1695797 0 0 0 0 441285 672503 1205399 266385 0 0 0 0 0 262818 245506 324548 380804 0 0 418563 0 0 0 417006 343864 0 566899 0 364140 347199 0 402031 203571 268789 0 615881 511023 307521 0 306497 0 0 0 389341 0 441704 361844 0 0 0 0 166246 328972 244875 348950 -AAGADGAAAEEKTEFDVELTEVGPNKVK MGYG000002492_00338 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282481 0 0 0 0 0 230183 0 110228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1929793 0 1990898 818970 0 0 0 0 1220014 775951 1043607 0 0 1245433 0 0 0 0 0 208564 0 489875 0 0 0 0 0 0 1242159 0 1654986 0 0 0 0 2097513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGADSADNYEK MGYG000001338_02454;MGYG000000184_00715;MGYG000000213_00629 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3XYGX@572511|Blautia 1.0 186801|Clostridia 1.0 K 1.0 Psort location Cytoplasmic, score 8.87 1.0 yebC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Transcrip_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 574293 205389 0 478879 0 0 0 0 0 577126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 148490 0 0 0 0 0 0 1073234 0 0 201599 0 0 0 0 0 121855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 871093 0 0 0 0 0 0 0 0 745037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 966987 190662 0 398177 0 0 0 0 0 366171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732612 0 283021 0 0 0 0 156317 0 864413 551200 0 0 0 0 0 0 0 389816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 975860 0 984537 0 0 0 0 450139 -AAGADSADSYEK MGYG000000031_02633 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066205|m__MGYG000000031 1.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3XYGX@572511|Blautia 1.0 186801|Clostridia 1.0 K 1.0 Psort location Cytoplasmic, score 8.87 1.0 yebC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Transcrip_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 350156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGADYVGAD(Methyl[D](Asp->Glu)DLIPR MGYG000004733_01323 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1008261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 786184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324290 0 0 0 0 0 0 0 0 0 0 598377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGADYVGADDLIPR MGYG000004733_01323 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1788723 0 679626 0 0 0 0 0 0 937649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGADYVGAEDLIPR MGYG000000171_01515;MGYG000001439_02403;MGYG000002298_02666;MGYG000000212_02414;MGYG000000252_00576 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 1392309 2610651 861345 2119397 4002257 0 1750812 0 1387664 3313987 1244739 1789047 0 1668552 2029645 1581804 2387872 1235385 1011663 1120604 4061182 1516643 1496561 1138287 992987 1023407 1854369 2395317 1372853 2449591 1195638 2181682 0 0 0 866340 2482021 356165 564691 452121 278501 343211 0 0 314354 0 533316 570924 472105 361876 0 0 0 0 0 0 437464 423033 0 872675 0 0 841093 300485 413366 2150661 339459 601416 396761 549756 0 0 0 577924 369491 1099190 1108660 2337073 625507 1217375 769833 0 1160480 0 849227 894898 1327547 1346222 0 1292114 1323322 1510966 0 817430 891447 866364 1118223 436298 696882 1049713 774856 905906 2381492 0 752312 1752029 614785 1368226 0 0 0 907502 1425661 469902 432692 801588 546162 784830 431610 0 253484 0 259969 500579 517218 719115 0 241139 934942 399877 902883 276789 528508 338746 299738 0 759815 271458 226937 666538 1082246 4558927 325625 1302355 275503 757866 0 0 0 300356 1244339 628290 558931 512522 944029 311741 754401 0 358057 0 532644 219517 350105 142133 0 467455 285681 818024 329648 647386 779631 0 614183 515133 410326 324462 385958 409276 701485 225318 695775 470118 493282 413574 0 0 0 424585 480961 -AAGADYVGDQDMITK MGYG000003891_01844 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3WH4A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 780498 0 0 0 0 0 0 0 0 0 0 1410657 0 0 0 0 1828150 0 0 0 0 1671666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGADYVGEMDLVEK MGYG000004475_01000;MGYG000002143_01055;MGYG000004487_00621 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,2N6EQ@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 935803 0 0 1545128 0 645059 0 1883933 1390508 1412733 0 0 0 0 0 0 0 0 0 0 1187361 672054 0 803176 0 1289821 0 0 0 0 0 0 0 0 795017 0 895194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 689588 0 0 0 0 0 0 0 0 0 0 0 368508 313121 0 0 0 492121 0 0 0 0 0 0 0 0 0 0 0 0 508200 0 0 406600 0 1407283 0 876899 850443 871023 0 0 0 0 0 0 0 0 0 0 613088 805852 0 637647 0 826590 0 0 0 0 0 0 0 0 1235466 0 1071519 0 0 0 0 0 0 0 0 0 0 311158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178453 0 0 0 -AAGADYVGGDELIPK MGYG000001315_01189 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 720798 2041069 0 0 636771 0 0 0 725916 1602988 1073648 0 0 0 0 0 523898 705048 848148 0 852323 315966 496074 885760 0 0 363155 0 471396 0 631790 1259418 0 0 0 0 1576190 0 1625948 1776466 0 0 1061712 0 0 0 1221505 863925 887091 0 0 0 0 0 712996 1495972 1812187 0 607063 882584 1678020 1237126 0 0 798869 0 1057033 0 1697897 1768036 0 0 0 0 1886048 0 355610 383317 0 0 312520 0 0 0 459488 415790 386831 0 0 0 0 0 459363 260452 299541 0 0 605222 0 0 0 0 919764 0 407459 0 368761 381053 0 0 0 0 409915 0 552418 1893677 0 0 847039 0 0 0 915017 694985 2287186 0 0 0 0 0 0 0 521246 0 1017043 0 582780 0 0 0 1011573 0 420553 0 599457 1994686 0 0 0 0 0 0 0 1945821 0 0 443902 0 0 0 588054 760412 702982 0 0 0 0 0 0 566931 380485 0 399944 278794 207785 625722 0 0 0 0 360613 0 421776 2429478 0 0 0 0 1954366 -AAGADYVGGEE(Glu->Asp)LIPK MGYG000001637_00078 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp900543445|m__MGYG000001637 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1477547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2253339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGADYVGLDEYVEK MGYG000001415_02510;MGYG000003493_00379 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,2FNKI@200643|Bacteroidia,22UY1@171550|Rikenellaceae 0.5 976|Bacteroidetes 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 821913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 941493 0 798152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAEAADNYER MGYG000000133_01488 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3XYGX@572511|Blautia 1.0 186801|Clostridia 1.0 K 1.0 Psort location Cytoplasmic, score 8.87 1.0 yebC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Transcrip_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116603 0 0 0 0 0 0 0 0 0 0 216304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152555 0 0 365741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161162 0 0 0 0 336622 902776 0 793962 1242958 0 0 1021791 0 565407 0 0 0 1116864 1486798 473047 0 0 0 0 0 0 0 0 0 1057301 811123 0 0 0 0 0 0 1608681 0 850720 0 801942 636990 -AAGAEAAMQC(Carbamidomethyl)EQNTLNK MGYG000003266_01410;MGYG000002775_00323;MGYG000004681_00140 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG3968@1|root,COG3968@2|Bacteria,2GMA9@201174|Actinobacteria,4CUXX@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 S 1.0 Glutamate--ammonia ligase, catalytic domain protein 1.0 glnA 1.0 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 GABAergic synapse;Necroptosis;Glyoxylate and dicarboxylate metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 750210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797584 0 0 0 0 375983 0 0 0 0 718267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAEFVGAEDLIPK MGYG000000200_03209;MGYG000002985_00771;MGYG000001338_03534;MGYG000000133_01992;MGYG000002312_03039 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1248171 0 2578514 934193 4014651 1159539 813196 1574846 1093566 0 3339510 0 2352128 1079786 1424933 1907025 0 2184308 1234528 0 1312193 1500362 1310575 513495 0 1034377 741792 0 0 0 1998342 4183713 1491593 867880 1073790 1104393 1003481 1847828 657679 0 305931 799489 0 653229 719818 881267 485965 1052568 1045484 516825 1551377 521896 632524 633950 394245 3222404 807985 0 376830 439567 1146486 0 573444 735149 820841 1976649 919215 579301 7737749 0 522468 468313 706626 0 611009 441639 1014502 6525872 1303254 1066568 833261 926521 788696 969509 761715 1005101 0 0 1733936 810382 0 1644155 960726 284753 939716 1043874 1007829 1253816 660602 878357 1098851 902911 0 963999 812155 0 1495406 0 1886566 1101875 1052921 776589 890027 1118612 940303 0 0 860249 0 1064249 942960 793530 840138 1024931 0 0 0 868130 840671 0 988019 823719 659251 1064718 855747 1101332 500955 1295286 784161 753598 847167 1431417 0 883653 7082895 0 0 454703 333819 925962 756394 2130475 5813280 13949750 8550876 9166833 2450410 3353253 7503721 5130903 3825751 7711872 7205817 5290779 5930601 11451546 5738413 5386610 5368734 985275 5517581 1964487 6503617 4817548 1568511 4676288 6064865 4965144 7489802 2151724 10518315 1519100 9176207 14731550 11977472 5585506 4232391 6660803 3907261 5585724 -AAGAEFVGAEE(Glu->Asp)LIPK MGYG000002528_01114;MGYG000004296_01660;MGYG000000262_02173;MGYG000000028_00271;MGYG000000050_01365 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 0.6 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1469658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1770526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAEFVGAEELIPK MGYG000002528_01114;MGYG000004296_01660;MGYG000000262_02173;MGYG000000028_00271;MGYG000000050_01365 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 0.6 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 639039 0 0 0 0 0 0 0 0 0 0 1741464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 542397 0 0 0 749601 889581 1571588 0 0 0 1562285 781484 0 562863 0 0 0 0 0 0 0 0 4632029 1023942 0 0 3283316 750501 717382 460846 1479674 0 1171215 0 589159 966228 0 501694 0 761314 702503 0 6045921 0 1550498 0 0 733281 0 3817164 0 796613 3916112 0 3290558 868753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 482591 0 0 0 666404 0 845919 0 0 0 0 2299337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1927083 0 0 0 0 0 0 0 158038 0 0 0 0 0 0 0 1483395 828143 0 0 0 0 1123747 0 0 0 0 476058 0 0 0 0 0 -AAGAEFVGAEELVPK MGYG000003335_00786 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__GCA-900066135|s__GCA-900066135 sp900543575|m__MGYG000003335 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 504469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAEFVGG(Gly->Ala)DELIPK MGYG000000095_03286 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__GCA-900066755|s__GCA-900066755 sp902363085|m__MGYG000000095 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,25VN3@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2181435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAEGGAEEKDEFDVELTEVGGAK MGYG000002528_01112;MGYG000000028_00269 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,36IQP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 299281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 678129 0 391542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375313 0 145769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAELLC(Carbamidomethyl)ETTLEK MGYG000001338_03411 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3WHNU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GHMP kinase family 1.0 galK 1.0 - 1.0 2.7.1.6 1.0 ko:K00849 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00554,M00632 1.0 R01092 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 galactokinase. - Part of the Leloir pathway for galactose metabolism.-!-The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine. alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+). 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1822742 0 0 0 0 0 0 0 -AAGAELVGM(Oxidation)EDLAEQIK MGYG000002494_02478;MGYG000002477_00980 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,3WVKV@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAELVGMEDLADQIK MGYG000002506_03690;MGYG000003390_01040;MGYG000000235_04431 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,3WVKV@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 2782787 2821050 3050548 0 1110966 2724761 2719041 0 2385325 2377113 1445552 1978077 1743363 0 0 0 2273658 0 2850752 2126708 1335044 3216587 0 3273788 1965158 1841703 0 0 1815690 0 0 0 2962751 3071537 2444903 2481873 2168501 3041157 0 1262267 937641 0 0 0 0 0 3258286 0 903322 1074206 1233888 0 0 0 193742 0 915784 1826369 1838984 0 0 2133264 0 1222062 0 0 569192 0 0 0 0 3321729 5615894 0 0 0 1760315 963346 9885702 0 6871367 8567110 7436004 0 17844828 2163321 898143 7607703 2004211 0 0 0 7063225 0 0 2218586 7588561 9923701 0 30774370 1673909 17416831 0 0 0 0 0 0 1624225 1793885 13744949 11758687 10636765 11919253 16795136 8561371 15833148 0 0 15744295 25027397 0 8905855 24377881 2171344 8079846 14101486 0 0 0 15109577 0 16676100 16532664 12393990 33014560 0 12814157 14620060 9780950 0 0 18670901 0 0 0 6961105 32166231 9882975 23365071 0 14730657 5503082 324043 0 0 0 3267425 172058 0 4105879 185697 0 1035462 593332 0 0 0 277445 0 0 0 0 0 0 0 2837708 249074 0 0 1055238 0 0 0 63664 0 0 5410204 0 0 -AAGAELVGMEDLADQIKK MGYG000002506_03690 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,3WVKV@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAELVGMEDLAEQIKK MGYG000002494_02478;MGYG000002477_00980 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,3WVKV@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 267025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 648419 728166 0 0 0 1384924 0 0 0 0 0 0 0 394467 0 0 532283 0 0 0 0 1732961 0 1112767 1170081 509694 0 0 1027715 0 0 0 0 0 0 0 264957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437335 0 0 0 175241 0 0 0 0 0 0 0 102804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAETDKVSPLLLPNYAR MGYG000000002_00154 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A faecis|m__MGYG000000002 1.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WHXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 FAD binding domain 1.0 - 1.0 - 1.0 1.3.5.1,1.3.5.4,1.3.99.33 1.0 ko:K00239,ko:K00244,ko:K17363 1.0 ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 1.0 M00009,M00011,M00149,M00150,M00173,M00374,M00376 1.0 R02164,R10330 1.0 RC00045,RC00669 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,FMN_bind,FMN_red 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. | urocanate reductase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. | The enzyme functions as part of an anaerobic electron transfer chain that utilizes urocanate as the terminal electron acceptor.-!-The activity has been demonstrated with the artificial donor reduced methyl viologen. a quinone + succinate = a quinol + fumarate. | A + dihydrourocanate = AH2 + urocanate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Histidine metabolism;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 626312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 738705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176729 0 207059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAEYIVVPSMR MGYG000000003_01284 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,2FNWR@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 COG COG1082 Sugar phosphate isomerases epimerases 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 589893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443322 0 0 -AAGAEYVGAEELIPK MGYG000000080_02021;MGYG000004735_02574 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAF(Nitro)AQLLAR MGYG000003022_00729;MGYG000003352_01558 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,1KJ2C@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1054341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAFAQLLAR MGYG000003022_00729;MGYG000003352_01558 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,1KJ2C@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 102193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 951878 568378 0 0 0 646497 1046914 0 755793 0 0 0 0 0 0 0 0 569894 0 0 0 0 0 0 0 0 0 0 0 853841 640258 587852 0 1341305 0 0 604140 0 1954689 0 0 0 0 88488 787489 0 413323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553138 0 0 0 705696 0 0 111599 0 0 0 0 0 0 0 0 0 90453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405961 395152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAFAQLVAR MGYG000001410_00779;MGYG000004694_00685;MGYG000003170_00053 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella 1.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,4PQ90@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 445575 0 0 0 328113 0 230925 287296 0 0 0 655631 0 0 0 0 0 0 0 0 0 329010 0 0 0 0 639567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109212 0 0 376171 0 0 0 0 0 0 0 0 0 0 0 0 0 443140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1128829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 747573 0 0 0 789422 0 602740 891000 0 0 0 967241 0 0 0 0 0 0 0 0 0 984572 0 0 0 0 1888191 0 0 0 -AAGAGAAAAEEKTEFDVELTEVGPNKVK MGYG000000198_05826 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 278455 0 0 0 0 0 0 0 0 0 462940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766367 0 0 0 0 0 0 0 0 0 783003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 149927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180984 0 0 0 0 0 0 0 0 0 356276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272067 0 0 0 0 0 0 0 0 -AAGAGAAAEEEKTEFDVELTEGSGVPVIK MGYG000001319_01770 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,4BZC5@830|Butyrivibrio 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1854409 0 0 0 0 1801698 0 0 0 0 2148973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAGAAAEEEKTEFDVELTEVGPNKVK MGYG000000255_02155 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 674864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122471 0 0 0 0 -AAGAGAAAILTK MGYG000000212_00918 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Myosin-crossreactive antigen 1.0 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 814931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAGDGAAAEEK MGYG000002517_00194;MGYG000000245_03674 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 69003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406875 0 0 0 333885 0 0 0 0 0 0 340210 0 0 0 0 0 0 0 0 0 468082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 198247 0 0 0 0 0 0 282932 0 0 0 0 0 0 0 0 0 320986 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAGDGAAAEEKTEFDVELTEVGPNKVK MGYG000002517_00194;MGYG000000245_03674 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 301615 0 0 0 0 399100 0 188121 494164 212841 0 0 211201 210778 176116 0 0 0 0 0 0 0 0 233713 491438 417441 363322 0 0 0 0 0 0 217263 240850 239118 291850 0 288175 0 0 0 0 525018 0 477732 0 249828 0 0 227453 575625 0 0 0 0 0 0 0 0 0 0 0 368871 0 0 0 0 0 0 0 518758 211656 0 573758 0 0 0 0 0 0 0 0 203154 171554 247826 0 0 108922 0 0 0 0 0 0 0 0 0 0 0 183082 456378 0 0 0 0 0 0 0 0 491472 267597 299834 0 1087239 0 0 0 0 689978 0 1317318 1303891 685694 0 0 298189 1070855 1208841 0 0 0 0 0 0 365526 0 339919 1312199 1449199 1198130 0 0 0 0 0 0 1560158 1539184 1191981 1431056 0 773173 0 0 0 0 881644 0 160113 603273 1080569 0 0 1308232 717927 947599 0 0 0 0 0 0 629075 0 743810 857304 642354 825981 0 0 0 0 0 0 683627 1003781 207298 681215 0 -AAGAGVAALAAGSHK MGYG000002517_00467 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Myosin-crossreactive antigen 1.0 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAGVIHK MGYG000002469_01020;MGYG000003683_00636 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4D18U@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 187181 559377 0 0 124565 0 0 0 0 0 0 0 0 0 0 0 297402 0 0 0 493577 373897 411829 0 0 0 383785 0 0 428495 0 693743 0 0 0 0 496281 0 1603469 2250277 0 0 3251941 0 0 0 0 0 0 0 0 0 0 0 4950938 0 0 0 1694835 3062341 6468713 0 0 0 7092370 0 0 4674841 0 1544463 0 0 0 0 2126606 0 884564 443503 0 0 142088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545651 141357 216253 0 0 0 666837 0 0 149466 0 1032546 0 0 0 0 436391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 66711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGANKIAVIK MGYG000001632_01220 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-170|s__|m__MGYG000001632 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,36IQP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1863623 0 -AAGANKLAIVK MGYG000000044_01728;MGYG000002438_02328 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 157880 0 142415 146570 223504 144532 75511 0 0 73862 0 151256 187595 0 0 176703 94663 0 68358 141658 263666 131751 0 154515 0 141269 0 0 80575 180693 177211 241228 246898 0 0 112779 173692 0 161347 0 0 0 374914 38523 0 0 0 154893 0 127473 257983 0 0 239816 98342 0 0 0 238505 67717 0 51797 0 130369 0 0 137270 0 73865 304761 0 0 0 121974 0 164933 0 0 119433 0 278636 168002 75352 0 0 87012 0 151857 90280 0 0 170429 114330 0 158985 63342 202370 195374 0 150086 0 65119 0 0 192228 73493 289638 385454 226438 0 0 150225 0 113036 62007 0 0 0 0 0 0 0 0 0 0 281966 0 0 0 79666 0 0 0 0 364140 0 0 0 0 0 0 0 0 84353 0 61924 0 0 0 70984 191626 0 930809 0 1475635 1680234 2877658 1538301 833151 0 0 2297120 0 3800058 2203805 0 0 1494670 1588484 0 781418 827407 1871591 826569 0 974825 0 1567933 0 0 952210 1767947 1514138 2328050 870490 0 0 1592628 0 1658896 -AAGANKVAVIK MGYG000002506_03692 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,3XPRN@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 981721 1279053 0 0 1364483 0 1023171 0 0 0 0 0 0 0 0 814094 0 0 977680 0 1770261 0 1336829 0 0 0 0 0 0 0 1104239 1202479 0 0 0 0 1437127 0 450323 226334 0 0 414398 0 132525 0 0 0 0 0 0 0 0 282660 0 0 114044 0 874941 0 335080 0 0 0 0 0 0 0 326222 251375 0 0 0 0 347831 0 1438027 577197 0 0 1051282 0 927889 0 0 0 0 0 0 0 0 283347 0 0 240472 0 958927 0 882301 0 0 0 0 0 0 0 900294 494500 0 0 0 0 342430 0 239382 411574 0 0 603521 0 1268226 0 0 0 0 0 0 0 0 340308 0 0 157300 0 797539 0 217757 0 0 0 0 0 0 0 855439 686968 0 0 0 0 243387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGASAQVLGQEGK MGYG000004789_00688 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Streptococcaceae|g__Streptococcus|s__Streptococcus sp001556435|m__MGYG000004789 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli 1.0 91061|Bacilli 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 748873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGASLLR MGYG000001300_02032 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,3WG9J@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 synthase 1.0 aroF 1.0 - 1.0 2.5.1.54 1.0 ko:K03856 1.0 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 1.0 M00022 1.0 R01826 1.0 RC00435 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAHP_synth_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-deoxy-7-phosphoheptulonate synthase. phospho-2-oxo-3-deoxyheptonate aldolase. Formerly EC 4.1.2.15. D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2- dehydro-3-deoxy-D-arabino-heptonate + phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of amino acids;Metabolic pathways;Biosynthesis of secondary metabolites;Phenylalanine, tyrosine and tryptophan biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3533144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGATSFDQYK MGYG000001313_02506 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32682217 0 0 0 0 0 0 0 0 0 0 0 0 34997357 0 0 0 0 30841112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGATTANITQAIEQMR MGYG000002506_02112;MGYG000002515_00455 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,3XN3I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 1.0 - 1.0 ko:K03695 1.0 ko04213,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - multiple species 1.0 none 1.0 665089 716248 0 0 0 1028073 905654 1211798 758457 1278253 0 0 0 0 0 0 0 0 0 575873 598980 948774 0 965563 511348 347812 600338 0 644720 863487 0 0 0 750412 836943 0 548948 0 0 0 0 0 0 374242 66886 0 0 79219 0 0 0 0 0 0 0 0 0 0 0 657341 0 602444 66338 77579 0 0 0 0 0 0 0 0 152678 0 0 0 515267 0 0 0 0 992071 394754 324665 290031 362690 0 0 0 0 0 0 0 0 0 0 229882 356748 0 521932 509972 563230 278397 0 210574 218167 0 0 0 377140 444817 0 550724 0 0 0 0 0 0 0 0 261766 0 0 0 0 0 0 0 0 0 0 0 157310 0 0 0 0 0 0 0 0 0 0 0 0 0 278353 95023 0 207678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGATTFDQYK MGYG000003681_00916 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692880 0 0 0 0 0 639926 770869 0 0 0 0 0 1060878 0 0 780696 0 0 0 0 0 0 0 0 732650 0 0 0 0 0 0 0 0 994394 0 653583 0 0 0 0 0 0 0 384401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGATTVSAPMPGK MGYG000001365_01216 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A|s__Phascolarctobacterium_A succinatutens|m__MGYG000001365 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 513380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444150 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308427 0 0 0 0 0 0 0 547966 0 575214 810792 0 0 0 0 0 0 0 0 0 0 0 678604 0 0 0 1069926 839345 804554 0 0 0 682230 1133931 0 818199 0 474712 0 0 0 0 619586 -AAGATVVSVTHAAGSALTK MGYG000000195_03246;MGYG000002040_01608;MGYG000002619_01556;MGYG000001255_01728;MGYG000002545_01644;MGYG000002610_01474;MGYG000003166_02168 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG2222@1|root,COG2222@2|Bacteria,1TRTA@1239|Firmicutes,24BGB@186801|Clostridia,3WJ2A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 M 1.0 SIS domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SIS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546800 528649 0 0 0 0 0 0 0 0 0 0 0 0 0 1341882 0 0 0 0 1058288 0 712626 0 0 853216 0 0 0 0 625736 0 0 0 0 686122 0 0 311786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1947558 0 0 0 0 2816640 0 0 0 0 2324499 0 0 0 0 407396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAVDGSDEK MGYG000003683_01237;MGYG000000756_00019 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4CYVV@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGE-sulfatase,Glucosamine_iso,PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 89535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109008 0 0 566702 0 294381 395029 0 0 0 313831 348191 0 882588 0 0 492903 0 1050674 0 0 0 183693 1009195 769400 0 0 374705 2261900 385003 0 1850181 0 212155 300755 166108 0 0 407272 0 0 141136 0 0 0 0 0 0 106511 0 0 120680 0 0 161732 0 0 0 0 0 0 100004 0 0 0 262952 67464 0 0 0 0 314964 280771 302811 0 0 84736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94379 0 0 46581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAVDGSDEKNAEAIKK MGYG000003683_01237 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4CYVV@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGE-sulfatase,Glucosamine_iso,PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 254741 0 199507 0 0 0 0 0 0 0 325897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87806 0 0 65856 0 145910 0 0 0 0 178295 0 393463 448801 0 361808 420329 0 0 0 0 0 0 1156866 0 0 0 0 1467678 0 0 0 299720 441557 813114 0 0 0 1019253 0 0 867229 0 428101 313846 0 0 0 427724 0 431666 217676 0 0 0 0 0 0 0 0 0 303542 0 0 0 0 0 0 0 0 206740 95123 0 0 0 0 236063 0 0 0 0 604058 383850 0 0 0 247697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGAVLMNMETK MGYG000000089_01614 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG1053@1|root,COG1053@2|Bacteria,2J6FD@203691|Spirochaetes 1.0 203691|Spirochaetes 1.0 C 1.0 PFAM fumarate reductase succinate dehydrogenase flavoprotein 1.0 - 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2381439 0 0 0 0 2804067 0 0 0 0 1825488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545593 0 0 0 0 312491 0 0 0 0 565936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1318237 0 0 0 0 802791 0 0 0 0 1519523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1277549 0 0 0 0 397294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 540740 0 0 0 0 403078 0 0 0 0 1076826 0 0 0 0 0 0 0 0 0 0 -AAGC(Carbamidomethyl)PDLNIQIK MGYG000000074_00674;MGYG000000053_01331 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,2FNGS@200643|Bacteroidia,22UCD@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin 1.0 ribH 1.0 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 2.5.1.78 1.0 ko:K00794 1.0 ko00740,ko01100,ko01110,map00740,map01100,map01110 1.0 M00125 1.0 R04457 1.0 RC00960 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DMRL_synthase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6,7-dimethyl-8-ribityllumazine synthase. lumazine synthase. Involved in riboflavin biosynthesis. (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Biosynthesis of secondary metabolites;Riboflavin metabolism 1.0 none 1.0 260652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368124 0 0 0 0 0 0 0 0 0 0 0 415950 0 0 0 241650 0 0 0 0 0 0 0 0 0 0 0 214658 188496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1041064 0 0 0 0 1002759 0 821851 0 0 0 0 0 750139 0 0 0 0 0 1849959 0 676329 0 709455 0 1112521 780557 0 0 1346681 672732 0 0 0 0 764096 1179922 0 -AAGC(Carbamidomethyl)PDMNIQVK MGYG000000003_00525 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,2FNGS@200643|Bacteroidia,22UCD@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin 1.0 ribH 1.0 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 2.5.1.78 1.0 ko:K00794 1.0 ko00740,ko01100,ko01110,map00740,map01100,map01110 1.0 M00125 1.0 R04457 1.0 RC00960 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DMRL_synthase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6,7-dimethyl-8-ribityllumazine synthase. lumazine synthase. Involved in riboflavin biosynthesis. (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Biosynthesis of secondary metabolites;Riboflavin metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 972164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGC(Carbamidomethyl)TAIIALGGGSPMDVAK MGYG000002448_00117 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Evtepia|s__Evtepia gabavorous|m__MGYG000002448 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WGYX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 - 1.0 - 1.0 1.1.1.1 1.0 ko:K13954 1.0 ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00623,R00754,R04880,R05233,R05234,R06917,R06927 1.0 RC00050,RC00088,RC00099,RC00116,RC00649 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. aldehyde reductase. Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Fatty acid degradation;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 823631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGC(Carbamidomethyl)TALIALGGGSPMDVAK MGYG000004736_00489 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Evtepia|s__Evtepia sp004554585|m__MGYG000004736 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WGYX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 - 1.0 - 1.0 1.1.1.1 1.0 ko:K13954 1.0 ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00623,R00754,R04880,R05233,R05234,R06917,R06927 1.0 RC00050,RC00088,RC00099,RC00116,RC00649 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. aldehyde reductase. Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Fatty acid degradation;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 544034 0 383896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 759367 0 567774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGDAAAAAK MGYG000002478_01081 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 679529 1773203 0 0 646408 0 0 0 0 429095 0 0 234026 641173 0 0 279201 0 0 0 612747 0 0 0 444353 319743 0 0 0 457537 0 0 0 0 494316 0 352008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 48283 0 0 0 0 0 0 0 0 0 0 0 0 0 670473 70432 0 0 0 0 0 0 0 91433 0 0 58994 44085 0 0 166719 0 0 0 0 0 0 0 0 239935 0 0 0 0 0 0 0 0 61457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGDAAAAAKAAADKAVADAKAEAIK MGYG000002478_01081 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGDAYVTQLGIDMAER MGYG000000099_02268 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,248K3@186801|Clostridia,26BE6@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Peptidase family C69 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,FIVAR,Peptidase_C69,SLH,fn3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 906424 0 0 452944 0 0 0 0 0 0 0 0 0 0 209623 961432 0 0 512672 0 0 0 0 0 453155 412170 0 0 0 0 0 0 0 0 0 609417 783560 0 751980 0 0 919722 0 0 0 0 1030995 0 0 0 0 0 1289083 1177521 0 0 830208 0 0 0 802896 833728 887409 0 0 274682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385778 0 0 0 0 0 0 0 0 343298 344169 328491 0 -AAGDEETFAAK MGYG000002919_01993;MGYG000001642_01511 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CU83@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 NADH flavin oxidoreductase 1.0 - 1.0 - 1.0 1.3.1.31,1.3.1.34 1.0 ko:K00219,ko:K10797 1.0 ko00360,ko01120,map00360,map01120 1.0 - 1.0 R02252 1.0 RC00669 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Oxidored_FMN,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-enoate reductase. | 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]. enoate reductase. | 4-enoyl-CoA reductase (NADPH). Acts, in the reverse direction, on a wide range of alkyl and aryl alphabeta-unsaturated carboxylate ions; 2-butenoate was the best substrate tested. | This bacterial enzyme catalyzes the reduction of either (2E,4E)-2,4- dienoyl-CoA or (2E,4Z)-2,4-dienoyl-CoA to (2E)-2-enoyl-CoA.-!-The enzyme from Escherichia coli contains FAD, FMN, and an [4Fe-4S] iron sulfur cluster. cf. EC 1.3.1.124. butanoate + NAD(+) = (2E)-2-butenoate + H(+) + NADH. | (1) a 4,5-saturated-(2E)-enoyl-CoA + NADP(+) = a (2E,4E)-dienoyl-CoA + H(+) + NADPH. (2) a (2E,4Z)-dienoyl-CoA + H(+) + NADPH = a 4,5-saturated-(2E)-enoyl-CoA + NADP(+). 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Phenylalanine metabolism 1.0 none 1.0 0 1102732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1483317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGDGAAAAEEKDEFDVELVSAGASK MGYG000000164_01127 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,27VNP@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 609176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGDGIGFNAAENKYEDMMK MGYG000001060_01600 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister hominis|m__MGYG000001060 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4H29X@909932|Negativicutes 1.0 909932|Negativicutes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 - 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2227012 0 0 0 0 2260224 0 0 0 0 1755162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGDSYGQHPVGTGPYK MGYG000002485_01346 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0747@1|root,COG0747@2|Bacteria,3785F@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1542685 1855893 2403271 0 1874795 3059029 1526538 0 0 3814586 3124099 1564727 2283581 1779080 0 3076443 1448334 0 1534180 1394638 1212162 3641624 0 2471007 0 1614502 1853174 0 0 1462784 2345590 3147226 2603619 1628856 0 1341459 1576617 2520451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGDTPYIVGEIK MGYG000002517_00839 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Phosphoribosylformylglycinamidine cyclo-ligase 1.0 purM 1.0 - 1.0 6.3.3.1 1.0 ko:K01933 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04208 1.0 RC01100 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphoribosylformylglycinamidine cyclo-ligase. phosphoribosyl-aminoimidazole synthetase. - 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino- 1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277375 0 0 0 0 0 0 0 0 0 453123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 631225 0 0 0 0 0 0 0 0 0 579960 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGDTPYIVGHMEAGEK MGYG000002528_00489;MGYG000000028_01458 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,27VFI@189330|Dorea 1.0 186801|Clostridia 1.0 F 1.0 AIR synthase related protein, N-terminal domain 1.0 purM 1.0 - 1.0 6.3.3.1 1.0 ko:K01933 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04208 1.0 RC01100 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphoribosylformylglycinamidine cyclo-ligase. phosphoribosyl-aminoimidazole synthetase. - 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino- 1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429914 0 0 0 0 0 0 0 0 0 468774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGDTPYVVGR MGYG000000184_02206;MGYG000001338_00068 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,27VFI@189330|Dorea 1.0 186801|Clostridia 1.0 F 1.0 AIR synthase related protein, N-terminal domain 1.0 purM 1.0 - 1.0 6.3.3.1 1.0 ko:K01933 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04208 1.0 RC01100 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphoribosylformylglycinamidine cyclo-ligase. phosphoribosyl-aminoimidazole synthetase. - 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino- 1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 1480001 0 0 1710359 0 0 0 0 0 0 0 0 0 0 0 0 770180 0 0 0 0 541195 0 0 0 0 767600 0 0 380901 1500922 0 0 0 0 0 0 0 3215040 0 0 850496 0 0 0 0 0 0 0 0 0 0 0 0 914262 0 0 0 0 534489 0 0 0 0 886592 0 0 2934895 1390606 0 0 0 0 0 0 0 2884664 0 0 455210 0 0 0 0 0 0 0 0 0 0 0 0 1205660 0 0 0 0 514956 0 0 0 0 2201026 0 0 418973 2244917 0 0 0 0 0 0 0 3628829 0 0 1925334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721665 0 0 2641882 2418380 0 0 0 0 0 0 0 1570292 0 0 555094 0 0 0 0 0 0 0 0 0 0 0 0 413588 0 0 0 0 0 0 0 0 0 376284 0 0 1264523 1484376 0 0 0 0 0 0 -AAGDVPTQEIMAASDKLK MGYG000001292_01832 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1927370 0 0 0 0 1281521 0 0 0 0 2268716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGE(Glu->Asp)AATAVAK MGYG000000196_05075 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 2AFRI@1|root,315TH@2|Bacteria,4PK03@976|Bacteroidetes,2FTKM@200643|Bacteroidia,4ARI1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 375139 0 428110 0 432526 182843 408689 356551 0 301494 484242 0 387120 0 310569 165390 0 0 353016 161632 0 292637 0 373424 0 405091 355523 0 0 0 0 629154 520650 0 0 289801 357662 467212 142558 0 318993 241720 228622 0 217811 321030 0 289458 204597 0 216720 0 89262 211432 198948 0 0 0 0 214277 0 0 0 0 153465 0 198231 276922 0 173003 599144 126552 0 0 0 206264 179388 0 260115 322167 161907 239169 233638 214414 0 237061 200067 0 400108 0 288157 261992 165555 0 552979 321651 0 370830 0 159200 0 146284 366921 0 187780 436253 0 75948 216986 227451 0 406266 143820 139963 0 0 0 159549 215748 151418 121437 0 0 0 230974 0 129352 0 0 0 0 0 201693 0 0 0 0 681870 0 146930 0 0 223854 262480 0 0 0 0 0 0 0 0 15098807 0 7191981 15325879 16120095 9536887 14639485 20834830 0 14129029 10607408 0 18296899 0 13738918 7539526 8101499 0 8572416 18982058 0 7146885 0 12311407 0 17750589 13759241 0 11009019 16694867 0 12776738 7550552 15664043 0 14341623 20109999 12609454 -AAGEAAQLMAK MGYG000000377_02054 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__UMGS1766|s__|m__MGYG000000377 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,267V8@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2415748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGEAFEK MGYG000001338_00105;MGYG000000200_01610;MGYG000000184_02260 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3XYP0@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Galactose mutarotase-like 1.0 - 1.0 - 1.0 3.2.1.20 1.0 ko:K01187 1.0 ko00052,ko00500,ko01100,map00052,map00500,map01100 1.0 - 1.0 R00028,R00801,R00802,R06087,R06088 1.0 RC00028,RC00049,RC00077 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH31 1.0 - 1.0 DUF5110,Gal_mutarotas_2,Glyco_hydro_31 1.0 3.2.1.20 1.0 GH31 1.0 GH31 1.0 GH31 1.0 alpha-glucosidase. maltase-glucoamylase. Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.-!-The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links. Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Starch and sucrose metabolism 1.0 none 1.0 0 227299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 560902 0 0 0 0 0 0 0 1474400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 891670 0 0 0 0 0 0 0 1817356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2262684 0 0 0 0 0 0 0 1861253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1812158 0 0 0 0 0 0 0 2468936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4222028 0 0 0 0 0 0 -AAGEALWTLR MGYG000000133_00022 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3XYWB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner 1.0 valS 1.0 - 1.0 6.1.1.9 1.0 ko:K01873 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03665 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 GH5_11 1.0 valine--tRNA ligase. valyl-tRNA synthetase. - ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 98744 119851 0 227946 538825 0 0 146024 0 96448 0 309623 0 380204 0 0 200879 0 344493 338586 0 481723 103803 0 128663 0 101773 0 0 0 0 0 0 285988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183112 0 0 0 0 0 0 0 0 0 0 0 0 242030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 617618 947300 0 477346 1099102 0 0 821204 0 810098 0 1307299 0 727047 0 0 673922 0 1041276 696479 0 488245 736697 0 896351 0 1432865 0 0 0 1304803 0 0 670957 0 430720 -AAGEGSTYWDDIR MGYG000001310_02117 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG0366@1|root,COG4733@1|root,COG5492@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,1UVIA@1239|Firmicutes,25KIT@186801|Clostridia,3WMI9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 N 1.0 Bacterial Ig-like domain 2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Big_2,CarboxypepD_reg,F5_F8_type_C,Flg_new,Glyco_hyd_101C,Glyco_hydro_101,Lyase_8,Lyase_8_C,Lyase_8_N,SLH,fn3 1.0 3.2.1.97 1.0 GH101 1.0 CBM32+GH101 1.0 GH101 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGET(Thr->Ala)LWTLR MGYG000000301_00138 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900541985|m__MGYG000000301 1.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3XYWB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner 1.0 valS 1.0 - 1.0 6.1.1.9 1.0 ko:K01873 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03665 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 GH5_11 1.0 valine--tRNA ligase. valyl-tRNA synthetase. - ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 820232 632000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478936 865025 0 0 0 0 0 426547 -AAGETVDVIGTSK MGYG000000223_03139 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,36DP8@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit 1.0 rplC 1.0 - 1.0 - 1.0 ko:K02906 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1258198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1370356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGEVLTQAK MGYG000002298_00115 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp000436615|m__MGYG000002298 1.0 COG1879@1|root,COG1879@2|Bacteria,1V11T@1239|Firmicutes,248RJ@186801|Clostridia,27TBD@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGF(Oxidation[F](Phe->Tyr)DVELTYSDNETDR MGYG000000171_01145 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3Y2A7@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10546 1.0 ko02010,map02010 1.0 M00216 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.5 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 768674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGFAEPSWIDK MGYG000002438_01893 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,2FQ86@200643|Bacteroidia,22X9Z@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase family, NAD-binding Rossmann fold 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 905227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1820887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGFAEPSWIDKMK MGYG000002438_01893 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,2FQ86@200643|Bacteroidia,22X9Z@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase family, NAD-binding Rossmann fold 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131260 0 0 0 0 0 0 0 0 973783 0 0 0 0 0 0 0 0 460966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179729 0 0 0 0 0 0 0 0 177664 0 0 0 0 0 0 0 0 289327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 680546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1044215 0 0 0 0 0 0 0 0 2652194 0 0 0 0 0 0 0 0 1550812 0 0 0 0 0 0 0 0 -AAGFDPYEIVK MGYG000003589_01350 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Dysosmobacter|s__Dysosmobacter sp900770295|m__MGYG000003589 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,2N6EY@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 GGGtGRT protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1389384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2462269 0 0 0 0 0 0 0 0 3060675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37696405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGFEIPED(Cation_Ca[II])ATILAAEC(Carbamidomethyl)K MGYG000003452_00078;MGYG000001490_00318;MGYG000000756_00970;MGYG000003683_01140 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 40173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 40129 0 0 0 0 69800 0 0 348980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271185 0 0 0 0 588106 0 0 136355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGFEIPED(Cation_Na)ATILAAEC(Carbamidomethyl)K MGYG000003452_00078;MGYG000001490_00318;MGYG000000756_00970;MGYG000003683_01140 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 192171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163668 0 0 456122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 486478 0 0 0 0 676857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 415521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGFEIPEDATILAAEC(Carbamidomethyl)K MGYG000003452_00078;MGYG000001490_00318;MGYG000000756_00970;MGYG000003683_01140 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 295265 433395 2787967 244404 574747 378892 0 0 0 0 287122 0 521411 343339 0 469663 0 349478 0 398960 0 376806 286137 294051 0 0 0 302418 420872 368086 708672 324504 1571076 0 0 0 0 1925969 557741 1222732 6825968 711193 1908437 3069309 723097 0 0 0 900018 0 1538475 544433 0 836622 0 1115953 0 707461 0 2027690 434795 5238276 0 671307 0 890163 1119587 691593 8653763 1297507 6477453 0 0 606726 588131 9203675 623862 812647 2032223 70843 2575499 1702961 2950575 0 0 0 1729938 0 406835 2446131 0 518307 0 0 0 499756 0 624163 782338 1478035 0 598370 0 990000 1638301 1588665 460601 0 4422282 0 0 2384366 570157 1829566 298246 306820 727919 404507 462482 948189 341293 0 0 0 337942 0 332594 219158 0 192389 0 0 0 354331 0 1550749 422980 208813 0 238055 0 0 316541 247016 123856 642898 196694 0 0 93896 327321 306441 327345 197502 37042 5619518 0 145448 0 0 0 0 238665 0 7146478 539724 0 3263425 0 0 0 0 0 1689715 0 60525 0 251004 0 189377 254818 0 51884 0 1294077 0 0 362380 0 293740 -AAGFENLK MGYG000000198_02425;MGYG000002835_00157;MGYG000000179_00718 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,21Y18@1506553|Lachnoclostridium 0.6666666666666666 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 6658457 0 0 0 0 0 7565299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6141771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2787094 0 0 0 0 0 0 3378994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3116224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6328579 0 5159666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGFISAEEMANFK MGYG000000198_00669 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,267SM@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 869124 566127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1179775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 755086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1185476 1067333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1212055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754699 940167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453992 0 0 0 0 0 0 0 0 -AAGFLTR MGYG000000201_02593;MGYG000000142_00583;MGYG000002925_00054;MGYG000000301_01483;MGYG000000171_01362;MGYG000000200_02986;MGYG000003012_00713;MGYG000000050_00963;MGYG000000133_01062;MGYG000000212_00914;MGYG000002966_01975;MGYG000001338_00476;MGYG000000002_00954;MGYG000000216_00022;MGYG000000213_02255;MGYG000000806_00037;MGYG000001319_01287;MGYG000003694_00799;MGYG000000489_02402 domain d__Bacteria 1.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae 0.7894736842105263 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 0.8421052631578947 rpsI 1.0 - 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 313078 3376712 2172855 0 2701014 3107311 1208298 1762674 1272738 1629645 2708519 2329162 2590056 1334202 1220742 2405417 1802737 1913000 1181862 1576526 2028483 3485350 2161387 1876109 0 1353219 1364986 2265968 2502889 2059372 2367713 2983064 1854832 1607142 1597824 1165239 329469 2301576 3041535 9089867 1962619 2200101 3103545 1833981 2938240 2610372 0 2336250 3258574 1575045 2778308 2097354 1671047 1531980 1825414 2825115 1651454 2462206 2320664 1161702 1647536 2223305 2041771 2274085 2744143 2423308 4339206 2650888 10579534 3455505 2197445 3091814 3318313 3113817 2375451 2502841 2241949 5943796 2754881 2249310 1057334 2283356 2044622 2535444 1347960 2296458 2112624 2158511 2705758 2154657 2154006 3012735 4034829 905199 2078919 2353320 2458978 4210496 1815057 2456592 2136159 2061392 2530803 2323954 2881359 2793461 3974210 6022119 3625951 2804635 2351867 1572802 2162216 2472683 903657 1142107 1087687 761140 1013683 717769 657430 684443 857915 834045 1174034 1230434 1289890 662233 605948 768330 714532 444826 607224 819596 834905 608632 292832 864150 613485 786254 684432 583094 1112233 864368 1178016 1479099 1100911 805442 734693 838683 685477 843737 11406548 19102459 13509463 11560882 5208536 8251808 14717702 11433492 8168132 12166568 15046547 10235263 7372060 16059536 11392890 10436473 8956680 2375657 9646386 5005903 12010012 12812491 3588024 8351919 9637545 12361650 11916032 4021563 14935373 0 13198254 16257687 18954883 10266820 9250206 10925884 6375900 9049318 -AAGFLTRDPR MGYG000000201_02593;MGYG000000200_02986;MGYG000001338_00476 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 1.0 rpsI 1.0 - 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGFVDKEGK MGYG000002528_00223 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,267YK@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01989 1.0 - 1.0 M00247 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 - 1.0 - 1.0 - 1.0 ABC_sub_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 168280 0 0 0 146092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208881 0 0 0 0 0 0 606525 0 330468 0 0 0 0 0 0 0 0 1245092 0 0 0 752758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 595471 0 1071057 0 0 0 0 915151 0 726089 940973 0 0 0 0 0 0 0 1495653 0 0 0 942609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2709438 0 788422 0 0 0 0 1999984 0 531682 2392487 0 0 0 0 0 0 0 1070279 0 0 0 216872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382017 0 419036 0 0 0 0 683244 0 1305890 1249912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3564 0 0 0 0 0 0 -AAGFVNLK MGYG000002517_01229;MGYG000000489_01917;MGYG000000271_00398;MGYG000000146_00520;MGYG000000133_00443 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia 0.6 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 237209 0 0 0 314907 0 0 0 0 0 0 800097 498536 0 472835 0 0 0 636592 0 0 0 0 0 0 0 0 0 0 124436 417296 436813 0 734592 0 344667 0 0 0 0 0 0 332702 0 0 0 0 0 0 595918 70379 0 0 0 0 0 75685 0 0 0 0 0 0 0 0 0 0 133010 0 0 0 0 0 0 0 0 141285 0 0 0 0 0 0 0 0 0 0 103723 0 0 358093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192542 0 0 0 0 170312 0 0 0 0 0 0 226365 0 0 0 0 0 0 0 0 0 0 0 0 0 588002 0 0 0 0 0 0 0 0 0 0 0 0 144881 0 0 0 677825 0 0 1562401 0 0 0 3525700 0 1113610 0 0 0 0 3398745 2363841 0 1713085 0 0 0 3379280 0 0 0 0 0 0 0 0 0 0 2301804 2549290 2653494 0 1861327 0 859870 -AAGFVTR MGYG000000223_03182 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,36IRJ@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 1.0 rpsI 1.0 - 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2481171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1135869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGGEAIFC(Carbamidomethyl)K MGYG000001338_01728 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,24DU0@186801|Clostridia,3WS77@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 IQ 1.0 Enoyl-(Acyl carrier protein) reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 294278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2204659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1475258 0 0 0 0 0 0 0 0 1066797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 425015 0 0 0 0 0 0 0 0 554475 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 593024 0 0 0 0 0 0 0 -AAGGEAQLM(Oxidation)AK MGYG000004540_01479 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__TANB77|f__CAG-508|g__UMGS1754|s__UMGS1754 sp900554815|m__MGYG000004540 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,267V8@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGGISSLDDAAK MGYG000002485_00103 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0274@1|root,COG0274@2|Bacteria,378X5@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 H 1.0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate 1.0 deoC 1.0 - 1.0 4.1.2.4 1.0 ko:K01619 1.0 ko00030,map00030 1.0 - 1.0 R01066 1.0 RC00436,RC00437 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DeoC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 deoxyribose-phosphate aldolase. phosphodeoxyriboaldolase. - 2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway 1.0 none 1.0 0 0 0 0 0 364642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438721 0 0 0 0 1078929 0 0 1740418 2519386 0 0 0 3178483 3673015 3210032 0 1740420 0 0 4587373 0 2054846 0 0 3005110 0 2241045 1628592 0 1979283 0 2185056 3114290 0 0 0 0 1640110 0 0 0 0 360021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1056828 0 0 1100298 0 0 0 0 1298273 578214 0 0 601515 0 0 829813 0 931414 0 0 0 0 0 962571 0 0 0 945246 0 0 0 0 0 706167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGGISTVD(Methyl[D](Asp->Glu)DMEK MGYG000000195_02256 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_E|m__MGYG000000195 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,3WIFE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate 1.0 deoC 1.0 - 1.0 4.1.2.4 1.0 ko:K01619 1.0 ko00030,map00030 1.0 - 1.0 R01066 1.0 RC00436,RC00437 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DeoC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 deoxyribose-phosphate aldolase. phosphodeoxyriboaldolase. - 2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2057465 0 0 0 0 1388250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGGISTVEDMEK MGYG000000022_01714 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,3WIFE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate 1.0 deoC 1.0 - 1.0 4.1.2.4 1.0 ko:K01619 1.0 ko00030,map00030 1.0 - 1.0 R01066 1.0 RC00436,RC00437 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DeoC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 deoxyribose-phosphate aldolase. phosphodeoxyriboaldolase. - 2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 620501 0 0 0 0 1307935 0 0 0 0 1118200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 497302 0 0 0 0 935333 0 0 0 0 681871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2057375 0 0 0 0 0 0 0 0 0 1468572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582056 0 0 0 0 496685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3253576 0 0 0 0 2444784 0 0 0 0 2982535 0 0 0 0 0 0 0 0 0 0 -AAGGLAIIGTER MGYG000004876_03018;MGYG000003446_01379;MGYG000002082_00188;MGYG000000196_00565;MGYG000003681_00908;MGYG000003415_00077;MGYG000002281_02559;MGYG000002560_02882;MGYG000001789_02114;MGYG000003279_02202;MGYG000002867_01114;MGYG000000224_00045;MGYG000004720_00894;MGYG000000174_01535;MGYG000001643_03002;MGYG000000074_01471;MGYG000002293_00348;MGYG000000138_02590;MGYG000004468_01109;MGYG000001345_01168;MGYG000004185_00678;MGYG000001661_01341;MGYG000001378_02410;MGYG000000029_02205;MGYG000003952_00490;MGYG000000170_01936;MGYG000001313_02498;MGYG000000105_01224;MGYG000000098_00020;MGYG000004797_04099;MGYG000001346_01064;MGYG000003363_01411;MGYG000003697_01634;MGYG000001783_01010;MGYG000003282_00871;MGYG000000003_01952;MGYG000001415_00080;MGYG000004763_02200;MGYG000000243_00140;MGYG000002561_02517;MGYG000004479_01148 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,2FMVF@200643|Bacteroidia,4AMYA@815|Bacteroidaceae 0.5609756097560976 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane 1.0 secA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 0.9512195121951219 - 1.0 ko:K03070 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 1.0 - 1.0 - 1.0 Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW 1.0 - 1.0 - 1.0 GT41 0.8048780487804879 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 6612525 3214927 4681316 5842006 4265720 4207735 8550578 0 0 3273945 3819355 0 7380208 4768897 0 7885675 5419886 1790349 3081560 4200253 0 3912180 0 6399744 0 5392892 3641622 1598876 4132204 5282673 5328229 4000436 4230040 4733672 3737224 6945492 3881840 4831955 0 1233499 0 314798 6200200 0 0 0 0 4435103 0 1202537 10382189 0 0 0 0 1565417 4932915 0 0 402542 2253892 1388926 0 5106836 4390906 1166515 4136273 0 0 4632397 4403998 2066730 0 0 4509367 2121834 1399085 5019667 0 1647388 0 805074 5501174 0 0 3262864 564231 523873 0 0 0 0 3996116 677525 1588027 4106546 0 0 3036820 1907882 0 1330466 1171799 2111177 0 883295 1322525 1186211 0 1450811 5016163 4906001 455158 0 2786533 3009701 3631645 2519990 2943504 3553389 3126579 0 0 2857569 2821708 2728477 3081617 2221443 0 3075773 2403205 2915843 3121075 467824 0 3759936 3364932 2387871 0 2976032 2935439 1112772 3224122 2534436 2463411 2853596 3566230 2879628 3098510 3578967 3138904 3239096 2897051 2524180 2762860 2900010 0 0 3005861 0 0 2388204 2745561 3768956 0 2046196 0 0 4153883 1052140 3078508 0 0 2695610 0 0 0 2840061 2309217 0 3233108 5474043 2266294 2549873 1208570 3123273 2596323 2402817 0 3251265 -AAGGLAIIGTERHESR MGYG000004876_03018;MGYG000000196_00565;MGYG000001337_01556;MGYG000003279_02202;MGYG000000224_00045;MGYG000004797_04099;MGYG000001783_01010;MGYG000003363_01411;MGYG000000074_01471;MGYG000001415_00080;MGYG000001345_01168;MGYG000004468_01109;MGYG000004763_02200;MGYG000000243_00140 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,2FMVF@200643|Bacteroidia,4AMYA@815|Bacteroidaceae 0.7142857142857143 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane 1.0 secA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 1.0 - 1.0 ko:K03070 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 1.0 - 1.0 - 1.0 Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW 1.0 - 1.0 - 1.0 GT41 0.8571428571428571 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGGLNAAETKPQAK MGYG000003022_00004;MGYG000003352_01218 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG1053@1|root,COG1053@2|Bacteria,1R0GI@1224|Proteobacteria 1.0 1224|Proteobacteria 1.0 C 1.0 FAD binding domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2640512 2554240 3454841 2988413 3235161 2678306 2217364 4763107 2954389 3516957 3397121 2598488 2476009 2850999 2714169 2755095 2316737 881113 2749895 2147792 2350124 2401028 1340844 1962631 2598392 2896868 2697678 1002355 2693225 2367756 2388217 2627040 3388762 2572979 5210800 2437750 2470464 3096522 942612 1403972 1086379 958478 1544762 1869603 1263203 2405916 924889 1027871 1274101 1383755 920721 1026227 848248 1061992 1014521 1689894 1119460 901313 1015250 1099885 1395194 1718109 863041 281757 1229774 1356380 1192387 1230890 1644465 1442705 795405 1113040 2730396 1647004 857548 991977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249002 0 0 0 0 0 0 191660 227930 0 0 171031 0 0 0 0 186169 0 101775 214642 64534 0 0 0 0 0 0 0 0 226256 143080 145169 0 0 201583 0 169601 0 -AAGGLNAAGTALQQAK MGYG000001410_01025 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__Sutterella wadsworthensis_A|m__MGYG000001410 1.0 COG1053@1|root,COG1053@2|Bacteria,1R0GI@1224|Proteobacteria,2WF5S@28216|Betaproteobacteria,4PQ7T@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 C 1.0 FAD binding domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1721383 0 0 0 0 1358288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1302055 0 0 0 -AAGGMDDGGFGTSFEK MGYG000000179_02179;MGYG000000262_00845 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,24N8B@186801|Clostridia,22050@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 S 0.5 PTS system fructose IIA component 1.0 - 1.0 - 1.0 2.7.1.121 1.0 ko:K05881 1.0 ko00561,map00561 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000,ko02000 1.0 - 1.0 - 1.0 - 1.0 EIIA-man 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism 1.0 none 1.0 0 0 0 0 0 388524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 671691 0 315680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 473076 0 370962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 977876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1208868 0 374647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1747877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1567398 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525913 0 496886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGGNIIPSSTGAAK MGYG000000074_00883;MGYG000004658_00366 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,22V16@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 582602 0 0 386773 191964 0 590611 0 352258 0 0 0 149976 275624 0 190891 537101 0 0 388550 0 0 0 575023 572797 506675 511356 0 408288 304353 0 0 0 0 0 717497 445097 0 2200469 1745171 2289049 2421462 2033359 1476970 1550145 2507322 2576164 2631746 1686486 1867924 1332223 2491671 2688761 2004984 1684929 0 2814827 3479970 2407463 1560350 0 1358760 1952704 2519134 2343739 0 1689407 2478684 1567457 2238341 2105455 2742877 2857900 2210264 2300260 2361737 0 0 0 0 0 0 135258 0 0 0 0 52875 0 0 0 0 0 0 0 0 0 0 0 100451 0 0 0 0 0 0 0 0 0 0 0 0 96619 0 401830 0 0 138634 0 178905 158104 549234 509926 0 0 634998 0 0 874083 0 0 0 470637 493032 749552 0 0 0 554436 858292 479139 0 0 303372 0 351617 0 0 740885 697127 597070 0 15765635 10639435 12700265 20978306 19601064 19434074 12590327 15446981 18739455 14368371 7610433 15616391 19724208 9156489 14373517 14344792 16945594 1360004 26503279 32470743 12356126 13521038 1298668 14514298 12447508 23821032 11769577 1197839 15481093 24558134 13017594 12209745 10459761 1019618 12985384 12992033 17355409 14549834 -AAGGSNYMYDINDAELNK MGYG000002882_00261 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435975|m__MGYG000002882 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia,2PQYQ@265975|Oribacterium 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306480 0 0 0 0 760082 0 0 0 0 692068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGGTVFTAEEAK MGYG000000154_01299;MGYG000002517_00535;MGYG000002492_00656;MGYG000000245_02013;MGYG000000389_02154 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Carbamoyl-phosphate synthetase ammonia chain 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 595572 0 363797 329655 0 0 0 364198 394121 0 0 0 344158 597604 545943 0 0 0 321456 395459 0 0 0 0 682913 613282 692761 0 0 764800 0 0 366050 0 695825 345337 701739 464957 0 0 0 423036 0 0 0 0 0 0 0 0 0 304246 0 0 0 0 0 0 0 0 0 0 0 312387 0 0 0 0 0 0 0 0 0 0 0 0 618556 0 883203 422327 0 0 0 679217 726802 0 0 0 674700 609568 668080 0 0 0 385613 686315 0 0 0 0 1011068 653692 683237 0 0 751824 0 0 919905 0 597313 560882 821650 904096 1089459 0 0 1259154 0 0 0 981250 1288515 0 0 0 0 1282228 1080578 0 0 0 730618 1347985 0 0 0 0 1401186 1093395 1272711 0 0 789648 0 0 357452 0 1260436 1049619 860959 219985 417723 0 500934 230821 0 0 0 920522 640721 0 0 0 366839 795727 625954 0 0 0 450605 0 0 0 0 0 655439 250560 552412 0 0 375163 0 0 331984 0 529487 509010 493319 455278 -AAGGTVFTAEEAKEVANR MGYG000002517_00535;MGYG000000389_02154 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Carbamoyl-phosphate synthetase ammonia chain 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 388036 0 0 455398 0 0 0 0 346009 0 0 0 0 481977 447839 0 0 0 455331 381579 0 0 0 0 0 496309 96496 0 0 505186 0 0 0 0 382817 176737 390047 0 404110 0 0 271985 0 0 0 0 160120 0 0 0 0 125238 198846 0 0 0 0 369966 0 0 0 0 0 255998 159281 0 0 255251 0 0 0 0 269668 489826 158023 0 164731 0 0 232626 0 0 0 0 254152 0 0 0 0 165195 313376 0 0 0 0 201702 0 0 0 0 0 294843 192669 0 0 219255 0 0 0 0 373375 213580 441345 0 1106120 0 0 771167 0 0 0 0 1292496 0 0 0 0 1274484 1231690 0 0 0 811725 902249 0 0 0 0 0 1073490 1030702 0 0 702821 0 0 0 0 1254748 978571 1259203 0 264447 0 0 0 0 0 0 0 412477 0 0 0 0 229697 347624 0 0 0 314722 89004 0 0 0 0 0 288750 165333 0 0 360048 0 0 0 0 171639 273931 464113 0 -AAGGVIIITTK MGYG000002438_00861;MGYG000001489_04986 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,22WS3@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2764215 0 0 0 0 0 0 0 0 0 2613943 0 0 0 0 0 0 0 0 0 0 0 2544672 0 -AAGGVILITTK MGYG000002438_00861;MGYG000002218_02008;MGYG000000355_00074;MGYG000002478_00138;MGYG000002834_00163;MGYG000001489_04986;MGYG000003521_00292;MGYG000001666_00694;MGYG000003697_02612;MGYG000002080_00857 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 0.4 976|Bacteroidetes 1.0 P 0.9 TonB-linked outer membrane protein, SusC RagA family 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 195466 0 0 0 123444 0 165353 113947 199483 0 129555 0 136650 0 161752 200724 203109 0 277079 0 0 0 226152 256409 0 200562 0 0 0 263277 141067 0 125951 560011 157502 577698 488215 258097 503093 0 343560 0 445431 214554 1257736 380119 534659 539348 0 437139 0 415091 387084 0 514872 301542 466784 482087 593860 561892 148910 129896 705135 278574 441135 475128 0 0 511839 328249 565649 444092 322148 379084 260361 397735 207628 0 318245 0 326624 0 942381 458409 0 254253 320578 269741 0 171374 241244 1059191 0 0 368076 174692 286048 0 0 0 546595 369867 308008 463874 0 367121 241037 281990 382800 1087688 1013518 1771324 797937 1492867 1615617 0 956420 0 775154 718814 1204737 1319971 844574 957665 1100199 669514 496057 695603 517309 1617967 1238176 1233772 1051094 906894 1124510 877312 307809 728470 693247 849879 1762788 1171456 0 1013276 830375 884491 1521676 0 4353983 1936319 2221229 0 2347423 0 2943415 0 3322891 2758956 7071467 3705565 2585291 0 3729479 2874775 1518787 2628987 2923901 9341747 2796535 1135361 3473036 0 0 0 1158699 3130501 9371146 2371831 8629655 1429054 0 2520261 2018915 0 2138305 -AAGGVILITTKR MGYG000002438_00861;MGYG000002218_02008;MGYG000000355_00074;MGYG000002478_00138 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,22WS3@171551|Porphyromonadaceae 0.75 976|Bacteroidetes 1.0 P 0.75 TonB dependent receptor 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 61608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127717 0 0 0 0 0 0 0 0 78918 0 62572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740013 351418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1038801 323153 0 233745 0 0 0 0 0 1118394 0 832279 0 0 0 0 0 0 -AAGGVILVTTK MGYG000003351_03677;MGYG000002171_02797 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FWW6@200643|Bacteroidia,4AWE3@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 H 0.5 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 270847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 954278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGGVVLITTK MGYG000002438_00862;MGYG000002438_04047 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,22WS3@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380445 0 0 0 0 0 0 0 0 280735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4877367 0 0 0 0 0 0 0 0 1427140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGI(Xle->Val)QILNTSGAPGEGAK MGYG000004763_01415 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FN3Y@200643|Bacteroidia,4AP89@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1586705 0 0 0 0 0 2250667 0 0 0 1320779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2030022 0 0 0 0 0 0 0 1728983 0 0 0 0 7578510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIADDKTEVTNK MGYG000004769_01211 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG1633@1|root,COG1633@2|Bacteria,1V6KG@1239|Firmicutes,4H9J5@909932|Negativicutes 1.0 909932|Negativicutes 1.0 S 1.0 PFAM Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 COQ7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 212053 0 0 256496 218069 0 0 76819 0 108867 169715 0 0 0 0 0 0 0 152133 0 0 0 0 0 0 0 0 0 0 0 0 0 74229 0 0 0 0 0 1583703 2426058 2388598 1335497 3187291 2212064 1200641 1990058 0 1892663 3026708 0 0 1870031 0 0 1665106 0 1422598 0 1444984 2291291 0 1868562 1395888 1404681 1633999 0 1443324 1732645 1946165 2999530 2406810 0 2023321 1439984 1311514 2059030 1219929 1555006 1855778 1098846 2969151 2420831 1967889 2016476 0 1445605 1971898 0 0 1698408 0 0 1032864 0 1416715 0 1358622 1409162 0 2225277 1738592 1548587 1471662 0 1461809 1597029 2250712 1561902 1086470 0 1047209 1677114 1292293 1473631 830030 187177 894662 354082 657405 780188 875510 924670 0 889881 599402 0 0 742382 0 0 547581 0 509659 0 706531 816540 0 464350 582109 581147 708260 0 580955 666951 363142 688150 943995 0 1009739 794240 824489 274816 0 0 0 0 0 0 0 0 0 0 209364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147766 0 0 0 0 0 -AAGIAEAR MGYG000001292_02345 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CZCD@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 213380 0 0 0 0 768396 0 0 940419 0 950747 0 471989 0 0 386654 0 0 0 0 240930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1119986 0 0 0 0 2771552 0 0 1431887 0 3337100 0 2801777 0 0 1765446 0 0 0 0 3277485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 205164 0 0 0 0 221206 0 0 902341 0 368153 0 871273 0 0 744699 0 0 0 0 843250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310962 0 0 457649 0 720260 0 482037 0 0 114270 0 0 0 0 351455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341721 0 0 0 0 1260659 0 0 198727 0 375435 0 181406 0 0 230052 0 0 0 0 96725 0 0 0 0 0 0 0 0 0 0 -AAGIAENVK MGYG000002494_02447 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,3XPPN@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1099897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIAEVFTPGTPTGNIVEFINANVK MGYG000004769_01825 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,4H4FB@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 B12- binding domain protein 1.0 - 1.0 - 1.0 5.4.99.2 1.0 ko:K01849 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00375,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 577902 0 200453 0 0 0 0 0 0 0 0 0 646639 0 0 0 0 0 0 0 0 0 0 623455 0 0 327145 1547181 0 0 0 0 0 0 0 255444 20651398 4770060 8271390 0 26542005 1819729 0 0 0 0 7889863 1487466 0 0 35080624 0 0 0 0 0 0 15734367 0 28976183 0 3155501 21883688 0 25824200 10868054 0 51581974 34111897 8253916 46783861 12260519 28317052 36966309 379628 2691702 2533801 0 27607303 14323755 0 0 0 0 7023662 812865 0 0 12838916 0 0 0 0 0 0 8281761 0 7321289 0 16985226 1458298 0 6568402 321939 0 7256114 2236262 1843607 19220288 4108783 16410063 9684570 0 0 4174248 0 0 0 0 0 0 0 0 2340756 0 0 3473938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4456591 0 0 0 0 0 0 0 12696133 17623005 0 16557288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 39595936 0 0 0 0 0 -AAGIAEVFTPGTPTSK MGYG000000591_01065;MGYG000001365_01211 genus d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A 1.0 COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,4H4FB@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 B12- binding domain protein 1.0 - 1.0 - 1.0 5.4.99.2 1.0 ko:K01849 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00375,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 1066128 0 0 920417 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257989 0 0 0 0 0 0 0 0 0 245950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283010 0 0 0 0 0 0 0 5163361 0 5997286 11092041 4934043 7433238 6674337 8692616 6902792 4944877 4326738 5040040 3733335 0 4776411 2777444 6367195 9217631 5701921 6415506 0 6582064 7665215 7050307 0 5526631 0 6477690 7188511 5559799 6672304 6590255 5944750 6427322 8850076 0 9325807 7339735 -AAGIALTDTFVK MGYG000004536_01441;MGYG000002867_00573;MGYG000001562_00044;MGYG000004006_01717;MGYG000000053_01377;MGYG000004756_01346;MGYG000002007_00386;MGYG000001415_02219;MGYG000001546_00360;MGYG000000003_00712 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,22V16@171550|Rikenellaceae 0.9 976|Bacteroidetes 0.9 G 0.9 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.9 gap 0.9 - 1.0 1.2.1.12 0.9 ko:K00134 0.9 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9 R01061 0.9 RC00149 0.9 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9 0.9 0.9 0.9 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9 none 1.0 9137639 6273728 3166831 9143720 2806299 5845774 10698492 4404817 9098516 6124232 2529795 7602601 3460873 7005245 6987548 5007318 6412706 0 9532434 9261265 8455369 4819183 0 7711376 6565616 8830242 11092433 0 8157343 9331651 4096474 5664866 3826416 3440179 6665094 10960322 7621237 2286142 1542630 1171274 2540584 1967525 2579597 2112016 1114307 1343160 2404284 2492949 1734039 0 1910050 2524227 2857754 2805104 0 0 1823715 1862768 3301863 2068369 0 0 2129561 1966303 2123820 0 1596594 2509398 1607554 2112962 2061621 271042 1421225 1632619 1948938 2412323 3560818 2535539 4336440 1988556 4693285 2097694 3616418 0 3929835 2469894 3192237 4427332 2415345 3131096 3315573 2738196 1758618 0 2901517 3198977 4504768 2199714 0 2718008 2916604 3033965 2414268 0 3295000 5481647 2891582 2023953 3826719 3845531 2631276 4292345 2665441 4681610 1575025 1352805 2080017 1089457 1928420 1589750 1653646 1975846 1496800 1587691 1412978 0 1665557 1772116 1996861 1669509 1435840 0 1959490 1378988 2227372 1000852 0 1008045 1827993 1895468 1571908 0 1836021 1802783 1878308 2246163 2026196 1909330 1661080 1707887 2200682 1496992 347151 316230 0 0 170776 206745 309796 0 237250 0 0 325271 114454 0 0 202163 125159 0 315849 781111 353455 257731 0 184222 375165 302362 125345 0 0 682399 0 165110 108611 0 0 311993 170584 133455 -AAGIAVQAFGYHNR MGYG000002517_01108 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 PFAM Aminotransferase class-III 1.0 argD 1.0 - 1.0 2.6.1.11,2.6.1.17 1.0 ko:K00821 1.0 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00028,M00845 1.0 R02283,R04475 1.0 RC00006,RC00062 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetylornithine transaminase. | succinyldiaminopimelate transaminase. succinylornithine aminotransferase. | succinyldiaminopimelate transferase. Also acts on L-ornithine and N(2)-succinyl-L-ornithine. 2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L- glutamate 5-semialdehyde. | 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (S)-2- succinylamino-6-oxoheptanedioate + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Lysine biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3334416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3363945 0 0 3923851 0 0 0 0 0 3692940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIDAQVIDPAEAR MGYG000003681_02758;MGYG000001661_00109 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0578@1|root,COG0578@2|Bacteria,4NJ15@976|Bacteroidetes,2FR3V@200643|Bacteroidia,4AQ69@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,DAO_C,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1608055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIDQEFVQDNQSSSR MGYG000000133_00721;MGYG000000301_00793 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1208@1|root,KOG1322@2759|Eukaryota,39UI6@33154|Opisthokonta,3BMQM@33208|Metazoa,3DRBA@33213|Bilateria,42230@6656|Arthropoda,3SQNT@50557|Insecta 1.0 33208|Metazoa 1.0 M 1.0 MobA-like NTP transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NTP_transferase,RmlD_sub_bind,dTDP_sugar_isom 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 576173 0 0 0 0 0 0 937391 663839 0 0 841531 517277 0 0 0 0 0 0 0 0 0 657514 0 861350 0 0 0 0 0 1009242 0 0 690206 0 554120 -AAGIDSVLSTGK MGYG000002494_02986 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,3XMEK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 M 1.0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein 1.0 murF 1.0 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.0 6.3.2.10 1.0 ko:K01929 1.0 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 1.0 - 1.0 R04573,R04617 1.0 RC00064,RC00141 1.0 ko00000,ko00001,ko01000,ko01011 1.0 - 1.0 - 1.0 iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090 1.0 Mur_ligase,Mur_ligase_C,Mur_ligase_M 1.0 - 1.0 - 1.0 - 1.0 - 1.0 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase. uridine diphosphoacetylmuramoylpentapeptide synthetase. Involved with EC 6.3.2.4, EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.8 and EC 6.3.2.9 in the synthesis of a cell-wall peptide.-!-Also catalyzes the reaction when the C-terminal residue of the tripeptide is meso-2,6-diaminoheptanedioate (acylated at its L-center), linking the D-Ala--D-Ala to the carboxy group of the L-center.-!-Formerly EC 6.3.2.15. ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma- D-glutamyl-L-lysine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D- muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine. 1.0 1.0 1.0 1.0 Peptidoglycan biosynthesis;Lysine biosynthesis;Metabolic pathways;Vancomycin resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIDTASGVPNK MGYG000003937_00913;MGYG000001157_02091;MGYG000004732_00999;MGYG000001627_00366 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WICR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 - 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 968582 495186 851497 0 999597 652341 841423 0 0 0 788630 0 947796 0 1100710 1006707 1778051 0 991471 1040639 937165 1664030 520131 0 0 0 1182008 0 700114 785437 0 910980 989393 0 1084191 0 620886 0 504782 705335 315834 0 482727 283818 653075 0 0 0 2165793 0 247161 0 487227 533394 1287393 0 342349 259127 481805 1713410 0 0 0 0 1591923 0 1643057 484428 0 770637 858284 0 379286 0 786132 0 721689 978529 789445 0 973862 824490 801439 0 0 0 938807 0 909920 0 843033 1204796 1419731 0 724062 1019853 866684 1244755 767939 0 0 0 1305327 0 1042142 1026085 0 691442 877801 0 805198 0 898618 0 959618 1052367 581074 0 1417898 1090261 594555 0 0 0 672839 0 813640 0 1323846 538135 1166331 0 1026693 480022 654962 457996 1839133 0 0 0 1232775 0 606488 1320644 0 896530 647135 0 870504 0 1283854 0 501132 559326 515038 0 472146 792726 961813 0 0 0 1734623 0 194608 0 726836 709318 3393474 0 612923 791875 701488 3611523 655753 0 0 0 3461735 0 872159 632437 0 329886 827535 0 1019132 0 628806 -AAGIEAAK MGYG000000756_00891;MGYG000002469_01727;MGYG000003383_00235;MGYG000001292_02316;MGYG000002469_00420;MGYG000003683_01099 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria,4CZDH@85004|Bifidobacteriales 0.8333333333333334 201174|Actinobacteria 1.0 G 0.8333333333333334 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate 0.8333333333333334 rpiA 0.8333333333333334 - 0.8333333333333334 5.3.1.6 0.8333333333333334 ko:K01807 0.8333333333333334 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.8333333333333334 M00004,M00007,M00165,M00167,M00580 0.8333333333333334 R01056 0.8333333333333334 RC00434 0.8333333333333334 ko00000,ko00001,ko00002,ko01000 0.8333333333333334 - 1.0 - 1.0 - 1.0 Rib_5-P_isom_A 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 ribose-5-phosphate isomerase. ribose phosphate isomerase. Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate. aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate. 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.8333333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5762588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 913506 0 0 0 0 2179910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIEKDTFIISC(Carbamidomethyl)DC(Carbamidomethyl)PR MGYG000001300_00586 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Belongs to the ribose-phosphate pyrophosphokinase family 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 344978 0 0 0 0 0 0 0 0 0 390144 0 616423 0 0 0 0 0 0 0 0 0 0 397914 0 0 0 0 887404 512518 829488 0 0 0 0 0 744595 0 956633 0 0 1138085 0 862602 881697 0 763662 0 602630 0 1001581 0 0 0 510426 0 0 0 896576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 123374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1001107 0 0 1045290 673122 848917 0 0 0 0 0 0 0 0 0 0 0 0 1076271 996002 0 0 0 0 0 1098487 0 0 0 985635 957664 0 0 0 0 0 0 0 0 0 0 484495 1847680 480503 0 0 0 0 0 272643 0 624311 0 0 784335 0 0 1339020 0 1106061 0 605104 0 1620699 0 0 0 0 0 0 0 896814 0 0 0 0 -AAGIENFIHVR MGYG000002717_02115;MGYG000001313_03171;MGYG000001661_02103;MGYG000002478_00339;MGYG000004185_02238;MGYG000000098_00636;MGYG000003693_01259;MGYG000000196_02287;MGYG000004571_01786;MGYG000002549_04226;MGYG000001378_04186;MGYG000003363_01959;MGYG000001346_00856;MGYG000001659_02213;MGYG000002540_00968;MGYG000000054_02931;MGYG000003312_00927;MGYG000004797_04223;MGYG000000243_02183;MGYG000003681_00141;MGYG000004763_00640;MGYG000001370_02455;MGYG000000236_01414 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 0.8260869565217391 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 0.8260869565217391 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 3130514 3048405 2931487 3367536 2580794 2383892 3827041 2914337 3467692 2726586 2728865 2778545 2215980 2959429 2464227 2680190 3343578 1174835 3051951 2502639 2827152 2436909 1561751 3433482 2553133 3867274 3347778 1483817 3193360 3144736 3465195 3370709 2904370 2971370 3277195 3587273 2751466 2841510 2247355 1157465 2274692 2677921 2778341 2231025 2082788 2512109 2758655 2854682 2436451 2821611 2729701 2438278 2814658 2501149 2425714 1242717 3037383 2345211 2533032 1959189 1516040 1794587 2153408 2376219 2803151 1298710 2038160 1982224 1402874 2729524 1864311 2187506 2796042 2170564 2517846 2170059 1953719 1706132 2315211 2098380 2789892 2414122 2885454 2147728 2251113 2124826 2574678 3097125 2179851 2456052 2005479 2019539 1727025 2056315 2243158 2121035 2046160 1726181 1763393 2338835 2284341 2098498 1935265 1570399 2168945 2191373 2420563 1519541 1793034 1373956 2076765 2732747 1907601 1972057 1105346 692084 1085264 969469 873211 774122 998255 1011991 961940 947045 900453 1136015 1036307 893356 1001785 782927 1027601 627288 1418217 1202274 1191860 782915 737035 631654 1019410 1035445 1036032 272239 922727 1074045 860911 1185203 883137 1144988 1087505 1249628 1163922 777912 1576114 1143086 1178480 1672049 2698996 1851887 1683267 2189704 1770320 1086602 1404829 1198170 1178712 967189 1356072 1726306 1541088 1768978 1715256 2212772 1124837 1646186 1495672 1772550 1413071 1353640 1371567 1368644 1968706 1983988 1453999 1386061 904054 1797707 2775240 1039066 1474007 1487788 -AAGIEPVGRPEVSVDSASEAEGATLTVK MGYG000002545_00080;MGYG000002040_00240 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053553 0 0 0 0 940132 0 0 0 0 993858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 691029 0 0 0 0 495322 0 0 0 0 728851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766572 0 0 0 0 783064 0 0 0 0 880226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188038 0 0 0 0 450414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIEQDFK MGYG000000243_01798 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 1673193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2563840 0 0 0 0 2265200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIESC(Carbamidomethyl)AFDR MGYG000003022_00716;MGYG000003170_00066;MGYG000001410_00792 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae 1.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,4PQ4Q@995019|Sutterellaceae 0.6666666666666666 28216|Betaproteobacteria 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 0.6666666666666666 rpsE 0.6666666666666666 - 1.0 - 1.0 ko:K02988 0.6666666666666666 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1069367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295661 0 0 844929 0 0 0 0 831472 0 0 214247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407747 0 0 0 0 0 0 0 279984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251310 0 0 0 0 0 0 0 391571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150990 0 0 184988 0 0 0 0 593641 -AAGIGGKGER MGYG000000255_02207;MGYG000000205_02701;MGYG000000233_02503 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,268N0@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 12448 19495 0 0 179560 0 98463 47744 257844 0 0 0 0 0 0 0 16386 0 85658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111072 175007 0 0 220782 0 80114 277178 92843 0 0 0 0 0 0 0 0 0 185771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190663 0 31896 80007 62144 0 0 0 0 0 0 0 26368 0 311202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132060 320128 0 0 78683 0 0 208734 80072 0 0 0 0 0 0 0 104189 0 84339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 33912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIGGRGER MGYG000000378_00784 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__|s__|m__MGYG000000378 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,21XUV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIGNIHGK MGYG000000233_01876;MGYG000000146_01173;MGYG000001319_01217;MGYG000000249_00065;MGYG000000217_00827;MGYG000000187_01350;MGYG000002772_00870;MGYG000000127_03839;MGYG000002141_00573;MGYG000000018_00752;MGYG000000142_01854;MGYG000002517_00490;MGYG000001423_01022;MGYG000001637_01196;MGYG000000262_02902;MGYG000002279_01206;MGYG000000223_01963;MGYG000000205_02362;MGYG000000179_01100;MGYG000000258_00162;MGYG000000198_00983;MGYG000001683_00168;MGYG000003694_02365;MGYG000000045_02322;MGYG000000484_00946;MGYG000000136_02629;MGYG000001315_01431;MGYG000000312_01744;MGYG000002492_00628;MGYG000000171_01775;MGYG000003921_02276;MGYG000000084_01948;MGYG000000216_03192;MGYG000000089_02421;MGYG000001338_00333;MGYG000000271_03469;MGYG000002974_01498;MGYG000001374_02205;MGYG000004296_00424;MGYG000002278_02388;MGYG000000077_01332;MGYG000000200_03096;MGYG000000076_01227;MGYG000000002_03797;MGYG000002528_01756;MGYG000001615_03374;MGYG000002312_00646;MGYG000001607_01064;MGYG000004667_03823 domain d__Bacteria 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia 0.22448979591836735 186801|Clostridia 0.9591836734693877 G 0.8571428571428571 Fructose-1,6-bisphosphate aldolase, class II 0.46938775510204084 fba 1.0 - 1.0 4.1.2.13 0.9795918367346939 ko:K01624 0.9795918367346939 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.9795918367346939 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 0.9795918367346939 RC00438,RC00439,RC00603,RC00604 0.9795918367346939 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.9795918367346939 0.9795918367346939 0.9795918367346939 0.9795918367346939 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.9795918367346939 none 1.0 617036 0 240330 352797 617998 0 0 0 465982 460786 476496 0 0 822557 990317 337046 386103 4842424 707071 626023 0 0 1964452 0 0 374913 433213 1790607 446154 476204 69495 305041 198629 0 593676 0 422311 299909 113195 0 106659 0 199089 0 0 0 51249 56022 65359 0 0 289221 193244 0 240549 1585040 46949 51669 0 0 1347760 0 0 102357 111372 1616646 119855 250741 106594 139686 134019 0 102166 0 0 150558 1908894 0 2613806 871277 892324 0 0 0 1995135 1401122 952987 0 0 1671779 2061344 1389330 1245031 881512 1924513 2498778 0 0 1134126 0 0 1552150 795838 1269473 1919926 2817907 1063885 568343 1910518 0 1479395 0 2172330 963640 2691916 0 1710317 3421921 2338706 0 0 0 3502391 2227266 2419902 0 0 1810410 2361464 1514746 2091762 2156975 1467677 2565587 0 0 425057 0 0 1695254 1819212 3294700 4118064 2809379 2778255 2290942 2119087 0 2406615 0 2738543 2780217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 186652 1334549 0 0 0 0 1719850 0 0 0 0 942460 0 3438 0 71530 0 0 34268 0 0 203573 -AAGIGNIHGKYPANWK MGYG000002517_00490;MGYG000000258_00162;MGYG000000233_01876;MGYG000001338_00333 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia 0.5 186801|Clostridia 1.0 G 0.75 Fructose-1,6-bisphosphate aldolase, class II 0.5 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822419 0 0 0 0 0 0 0 0 0 518230 0 0 0 0 0 0 0 0 0 0 424381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 377708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1771740 0 0 0 0 0 0 0 0 0 2941102 0 0 0 0 0 0 0 0 0 0 1639932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIGNIHGVYPANWK MGYG000002545_01061;MGYG000003899_02090;MGYG000000193_00938;MGYG000002040_02084;MGYG000000022_00043 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3WGNI@541000|Ruminococcaceae 0.8 186801|Clostridia 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 370138 0 0 0 0 0 0 0 0 579455 0 0 0 0 982850 0 0 0 0 572140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150310 0 0 0 0 0 0 0 0 1110548 0 0 0 0 1419023 0 0 0 0 1449291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522886 0 0 0 0 0 0 0 0 1935749 0 0 0 0 1878050 0 0 0 0 1505316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 617980 0 0 0 0 0 0 0 0 0 0 0 0 0 763151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1414718 0 0 0 0 1368912 0 0 0 0 1452985 0 0 0 0 0 0 0 0 0 0 -AAGIIR MGYG000003022_00727 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella|s__Parasutterella sp000980495|m__MGYG000003022 1.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,2VSE6@28216|Betaproteobacteria,1KM24@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 J 1.0 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome 1.0 rplV 1.0 - 1.0 - 1.0 ko:K02890 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L22 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 614064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIKADALK MGYG000001410_02104;MGYG000003170_01495 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella 1.0 COG1053@1|root,COG1053@2|Bacteria,1QDYN@1224|Proteobacteria,2W8FG@28216|Betaproteobacteria,4PQFK@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 C 1.0 Glucose inhibited division protein A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476452 0 0 0 497659 0 0 667062 0 0 0 0 0 0 0 0 371252 0 501686 0 0 0 0 0 0 678168 0 0 0 0 0 0 0 0 0 0 0 0 391015 0 0 0 548155 0 0 77816 0 0 0 0 0 0 0 0 0 0 72007 0 0 0 0 0 0 355301 0 0 0 0 0 0 0 0 0 0 0 0 606639 0 0 0 471592 0 0 960793 0 0 0 0 0 0 0 0 217375 0 258199 0 0 0 0 0 0 596138 0 0 0 0 0 0 0 -AAGILFAPESGEDTR MGYG000002478_04511;MGYG000002560_03419;MGYG000004797_02697 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4980@1|root,COG4980@2|Bacteria,4NXMW@976|Bacteroidetes,2FUB7@200643|Bacteroidia,4ARS7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG35214 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 YtxH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 3494496 0 3144748 0 0 3342005 3883191 0 3857716 3283920 3264905 3633634 4383869 3642196 3382223 4698603 0 2327022 4265630 3295686 2977510 3008463 2902873 4551884 3202401 4112989 4258167 3118233 3244740 3856279 4031235 4084160 2794201 0 3583681 4662200 3614001 3175690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 968840 0 0 0 0 1822562 0 0 5420979 0 1256352 0 0 0 0 0 0 0 0 0 0 3230254 0 3451433 0 0 0 0 0 0 0 3578392 0 3432506 0 3093849 3799960 0 0 0 0 0 2550031 2822672 0 0 0 3012550 2774102 0 0 0 0 0 0 3242219 0 0 0 0 0 0 0 0 1056881 810276 0 877699 1191988 887961 0 0 903823 1055303 1080610 0 200427 1509774 789908 1434849 1011416 464893 739848 1148635 760197 1168579 0 1186259 1044601 670533 1098620 877323 0 1735424 1347958 1069802 801547 0 0 1461559 0 0 2387793 1619263 0 1910341 1585486 749221 1217233 3161916 1831769 1720257 2416805 0 5324027 2798924 3043786 1236757 1038496 4185443 2192092 2613287 2173292 3029066 4088549 2719698 1699349 0 1702246 1796691 0 2025331 1683579 1848503 2206485 -AAGIMLSAADRFK MGYG000000243_01876 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3669@1|root,COG3669@2|Bacteria,4NGKB@976|Bacteroidetes,2FM4I@200643|Bacteroidia,4AKD0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Alpha-N-acetylglucosaminidase 1.0 - 1.0 - 1.0 3.2.1.50 1.0 ko:K01205 1.0 ko00531,ko01100,ko04142,map00531,map01100,map04142 1.0 M00078 1.0 R07816 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 NAGLU,NAGLU_C,NAGLU_N 1.0 - 1.0 GH89 1.0 GH89 1.0 GH89 1.0 alpha-N-acetylglucosaminidase. NAG. Hydrolyzes UDP-N-acetylglucosamine. Hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. 1.0 1.0 1.0 1.0 Glycosaminoglycan degradation;Metabolic pathways;Lysosome 1.0 none 1.0 0 230807 258715 0 0 0 0 0 0 0 194653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381507 0 0 0 0 258392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87341 0 0 0 0 0 0 0 0 209054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73005 0 0 0 0 103638 0 226210 127226 0 0 0 0 0 0 0 55114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351543 0 0 0 0 159748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIMLWK MGYG000000003_00845 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia,22U5J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 T 1.0 histidine kinase DNA gyrase B 1.0 htpG 1.0 - 1.0 - 1.0 ko:K04079 1.0 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HATPase_c_3,HSP90 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Estrogen signaling pathway;Antigen processing and presentation;Necroptosis;Prostate cancer;NOD-like receptor signaling pathway;Plant-pathogen interaction;Protein processing in endoplasmic reticulum;Th17 cell differentiation;Progesterone-mediated oocyte maturation;Fluid shear stress and atherosclerosis;Pathways in cancer;IL-17 signaling pathway;PI3K-Akt signaling pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 1779464 0 0 0 0 0 905521 0 0 0 1846483 1451967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 535478 0 0 0 0 0 202571 0 0 0 409450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199889 0 0 0 0 0 170262 0 0 0 372374 349883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196308 0 0 0 0 0 0 0 0 0 329082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180840 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGINAETIDPAEAR MGYG000001313_00697 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0578@1|root,COG0578@2|Bacteria,4NJ15@976|Bacteroidetes,2FR3V@200643|Bacteroidia,4AQ69@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,DAO_C,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGINPK MGYG000000074_00389 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,2FNBF@200643|Bacteroidia,22U65@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily 1.0 pheT 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 1.0 6.1.1.20 1.0 ko:K01890 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 B3_4,B5,FDX-ACB,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGINTASGKPN(Deamidated)K MGYG000003921_01311;MGYG000002040_00797;MGYG000002274_01728;MGYG000000022_00423;MGYG000001300_02638;MGYG000003166_01200 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WICR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 - 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490372 0 1061014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1759083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGINTASGKPNK MGYG000003921_01311;MGYG000002040_00797;MGYG000002274_01728;MGYG000000022_00423;MGYG000001300_02638;MGYG000003166_01200 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WICR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 - 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 887779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4210020 0 0 0 0 97376 0 0 0 0 3630653 0 0 0 0 489153 0 0 0 0 590704 0 579784 513884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 959001 0 0 0 0 1794105 0 0 0 0 1292617 0 0 0 0 664987 0 0 0 0 411340 0 266214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609808 0 0 0 0 514712 0 0 0 0 573986 0 0 0 0 0 0 0 0 0 0 0 1635468 1769760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8749073 0 0 0 0 9267733 0 0 0 0 160064 0 0 0 0 1576305 0 0 0 0 2431619 0 0 61965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1971560 0 0 0 0 1489909 0 0 0 0 891667 0 0 0 0 0 0 0 0 0 118199 -AAGINTASGKPNKEK MGYG000002274_01728;MGYG000002040_00797;MGYG000001300_02638;MGYG000003166_01200 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WICR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 - 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383533 570745 0 0 678488 0 0 0 512562 0 428419 0 0 0 599321 270050 0 0 0 0 469954 0 468109 0 0 359380 0 0 0 0 376819 0 0 0 0 399920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140115 0 0 0 0 69170 0 0 0 0 226114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 123069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511763 0 0 0 0 596740 0 0 0 0 395245 0 0 0 0 0 0 0 0 0 147175 -AAGIPC(Carbamidomethyl)GTEVEVK MGYG000003266_00144;MGYG000004746_00559;MGYG000000188_00406;MGYG000003274_01389;MGYG000000802_00030;MGYG000001636_01240;MGYG000002065_00911 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1925@1|root,COG1925@2|Bacteria,2H0K7@201174|Actinobacteria,4CWQ1@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 PTS HPr component phosphorylation site 1.0 - 1.0 - 1.0 - 1.0 ko:K11189 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 320958 0 0 599967 226403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1911476 0 0 2019158 1711487 0 0 0 0 0 0 0 0 0 0 0 0 2679880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIPFGYHNHEMEFAK MGYG000002438_03917 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1082@1|root,COG1082@2|Bacteria,4NJF7@976|Bacteroidetes,2G2TH@200643|Bacteroidia,231JP@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Xylose isomerase-like TIM barrel 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190874 0 0 0 0 0 0 0 0 120654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468439 0 0 0 0 0 0 0 0 623163 0 0 0 0 0 0 0 0 -AAGIPSLFMINK MGYG000004748_03039;MGYG000003533_02153;MGYG000000273_00707;MGYG000002614_01013;MGYG000001750_00508;MGYG000001789_00556;MGYG000000224_02142;MGYG000000042_01813;MGYG000000043_01365;MGYG000001313_01608;MGYG000001378_00878;MGYG000004479_02542;MGYG000001661_00715;MGYG000002478_03492;MGYG000001835_00920;MGYG000000415_00521;MGYG000001345_02954;MGYG000002007_01215;MGYG000003693_02501;MGYG000003351_05093;MGYG000000243_02912;MGYG000000196_04594;MGYG000001599_02528;MGYG000002203_01208;MGYG000004797_00255 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,2FM5R@200643|Bacteroidia,4APTB@815|Bacteroidaceae 0.88 976|Bacteroidetes 1.0 J 1.0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) 1.0 ileS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.5 1.0 ko:K01870 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03656 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,DUF559,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 isoleucine--tRNA ligase. isoleucyl-tRNA synthetase. - ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 674485 0 1707077 731298 1267774 695628 634845 707077 667026 559024 1068233 570958 1213969 493408 591257 1008427 744974 0 527218 289460 0 418195 224669 626942 315473 547287 783805 324896 0 720394 1222145 0 1882205 0 0 721956 577138 1515443 527621 0 698615 651747 873466 629170 701649 691136 607455 785117 1143719 635460 1201527 875705 622902 1124498 612724 906204 606811 826018 0 799815 1326193 477918 708667 559342 631190 881919 0 478057 531865 0 657456 0 0 567109 587768 569945 363893 0 359241 0 705533 600112 477420 381647 320753 402813 643191 552568 920690 306768 266647 677805 375344 759299 292385 431183 0 134960 439912 333565 370359 245102 265347 351001 0 364975 549530 0 119523 0 0 443172 399095 286207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1408123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273915 1212561 0 0 0 0 0 0 0 0 0 0 -AAGIPSLFMINKK MGYG000004479_02542;MGYG000002478_03492;MGYG000004797_00255 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,2FM5R@200643|Bacteroidia,4APTB@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) 1.0 ileS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.5 1.0 ko:K01870 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03656 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,DUF559,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 isoleucine--tRNA ligase. isoleucyl-tRNA synthetase. - ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316988 0 0 0 0 425811 0 0 0 0 326916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152847 0 0 0 0 0 0 0 0 0 73880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335182 0 0 0 0 285229 0 0 0 0 310618 0 0 0 0 0 0 0 0 0 0 -AAGITAVVFDR MGYG000001292_02346 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4D0WE@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4269894 0 0 0 0 1356004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176444 0 0 0 0 0 0 0 0 0 0 -AAGITMDPR MGYG000000080_03187 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DAO,FAD_binding_2,FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4847540 0 0 0 0 0 0 0 0 0 -AAGIVDGYGN(Deamidated)GTFGGDR MGYG000004769_01190 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG3203@1|root,COG3203@2|Bacteria,1V1RK@1239|Firmicutes,4H431@909932|Negativicutes 1.0 909932|Negativicutes 1.0 M 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Porin_4,Porin_5,SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGIVGMGGAGFPTGVK MGYG000002279_01084;MGYG000002992_00601;MGYG000000038_01565 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24AN3@186801|Clostridia,27WHN@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 RnfC Barrel sandwich hybrid domain 1.0 prdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,RnfC_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 562757 0 0 0 0 0 0 0 0 0 0 761307 549391 0 0 818734 988302 0 0 0 0 820323 0 0 0 0 0 0 0 0 288504 0 0 0 0 0 0 0 1241158 0 0 0 0 0 0 0 0 0 0 738476 400901 0 0 865068 1110574 0 0 0 0 930248 0 0 0 0 0 0 0 0 615361 0 0 0 0 0 0 0 1505256 0 0 0 0 0 0 0 0 0 0 1099051 904336 0 0 1640676 1484732 0 0 0 0 1264828 0 0 0 0 0 0 0 0 1011054 0 0 0 0 0 0 0 448037 0 0 0 0 0 0 0 0 0 0 236731 991919 0 0 523455 405512 0 0 0 0 482989 0 0 0 0 0 0 0 0 383578 0 0 0 0 0 0 0 1099274 0 0 0 0 0 0 0 0 0 0 865170 650614 0 0 786284 538293 0 0 0 0 511307 0 0 0 0 0 0 0 0 529901 0 0 0 0 -AAGIYVK MGYG000000223_01704 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,3VPMI@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1156386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3078167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92129 0 0 0 0 0 0 0 0 0 -AAGKDPFEITTYEQGIHAAEIK MGYG000002052_00057 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum|s__|m__MGYG000002052 1.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family 1.0 lysS 1.0 - 1.0 6.1.1.6 1.0 ko:K04567 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03658 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DUF2156,tRNA-synt_2,tRNA-synt_2_TM,tRNA_anti-codon,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine--tRNA ligase. lysyl-tRNA synthetase. - ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1087971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGKKEDIVVR MGYG000004271_00657 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG0451@1|root,COG0451@2|Bacteria,1TQW7@1239|Firmicutes,24BI6@186801|Clostridia 1.0 186801|Clostridia 1.0 M 1.0 CDP-glucose 4,6-dehydratase 1.0 rfbG 1.0 - 1.0 4.2.1.45 1.0 ko:K01709 1.0 ko00520,map00520 1.0 - 1.0 R02426 1.0 RC00402 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 GT9 1.0 CDP-glucose 4,6-dehydratase. - - CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H2O. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGKPNFYMFGEIC(Carbamidomethyl)TR MGYG000000258_01904 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Ruminococcus_E|s__Ruminococcus_E bromii_B|m__MGYG000000258 1.0 COG0366@1|root,COG3291@1|root,COG0366@2|Bacteria,COG3291@2|Bacteria,1V0U1@1239|Firmicutes,24ZQ4@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Alpha amylase, catalytic domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Alpha-amylase,CBM26,CHB_HEX_C_1 1.0 3.2.1.1|3.2.1.98 1.0 GH13_42 1.0 CBM26+GH13+CBM35+CBM25 1.0 GH13_42 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 619851 0 0 0 0 1015088 0 0 0 0 753825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGL(Xle->Met)AEDAAADEPLDFK MGYG000000074_02028 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG2968@1|root,COG2968@2|Bacteria,4NVTG@976|Bacteroidetes,2G3CT@200643|Bacteroidia,22UK1@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Protein of unknown function (DUF541) 1.0 - 1.0 - 1.0 - 1.0 ko:K09807 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 SIMPL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1027744 0 0 0 0 0 0 0 0 -AAGLDAIHDTVHEM(Oxidation)AR MGYG000004681_00940;MGYG000002961_00635;MGYG000000255_00995;MGYG000003266_00666;MGYG000001642_01559;MGYG000002775_00760 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,2HUEX@201174|Actinobacteria,4CUC5@84998|Coriobacteriia 0.8333333333333334 84998|Coriobacteriia 0.8333333333333334 C 1.0 Rubrerythrin 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 4855522 0 0 0 0 0 441728 0 0 0 0 0 0 0 1720545 0 1573627 0 0 0 0 951687 0 0 0 0 432706 0 0 0 0 0 0 0 4736819 0 0 0 1409061 0 0 0 0 0 1450055 0 0 0 0 0 0 0 855781 0 2613978 0 0 0 0 1784986 0 0 0 0 584359 0 0 0 0 0 0 0 0 0 0 0 377928 0 0 0 0 0 726162 0 0 0 0 0 0 0 944890 0 0 0 0 0 0 0 0 0 0 0 206940 0 0 0 0 0 0 0 0 0 0 0 594815 0 0 0 0 0 0 0 0 0 0 0 0 0 735399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446237 0 250843 0 0 0 0 315143 0 0 0 0 2958973 0 0 0 0 0 0 0 204293 0 0 -AAGLDAIHDTVHEMAR MGYG000004681_00940;MGYG000002961_00635;MGYG000000255_00995;MGYG000003266_00666;MGYG000001642_01559;MGYG000002775_00760 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,2HUEX@201174|Actinobacteria,4CUC5@84998|Coriobacteriia 0.8333333333333334 84998|Coriobacteriia 0.8333333333333334 C 1.0 Rubrerythrin 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 361664 0 493127 0 0 0 0 0 0 0 0 988589 0 0 0 0 1107320 0 0 0 0 745343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353577 0 410067 0 0 0 0 0 0 0 0 1435974 0 0 0 0 859119 0 0 0 0 971731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318225 0 423609 0 0 0 0 0 0 0 0 513486 0 0 0 0 667866 0 0 0 0 823235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254999 0 292922 0 0 0 0 0 0 0 0 758342 0 0 0 0 0 0 0 0 0 530220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270693 0 60504 0 0 0 0 0 0 0 0 445826 0 0 0 0 589124 0 0 0 0 739176 0 0 0 0 0 0 0 0 0 0 -AAGLDAIHDTVHEMARDEAR MGYG000004681_00940;MGYG000002961_00635;MGYG000000255_00995;MGYG000003266_00666;MGYG000001642_01559;MGYG000002919_00508;MGYG000002775_00760 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,2HUEX@201174|Actinobacteria,4CUC5@84998|Coriobacteriia 0.8571428571428571 84998|Coriobacteriia 0.8571428571428571 C 1.0 Rubrerythrin 1.0 - 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLDAIR MGYG000000271_03312;MGYG000004271_02207 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG4284@1|root,COG4284@2|Bacteria,1TQUD@1239|Firmicutes,24A8D@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.7.7.23,2.7.7.83 1.0 ko:K00972 1.0 ko00520,ko01100,ko01130,map00520,map01100,map01130 1.0 M00361,M00362 1.0 R00416 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 UDPGP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 UDP-N-acetylglucosamine diphosphorylase. | UDP-N-acetylgalactosamine diphosphorylase. UDP-N-acetylglucosamine pyrophosphorylase. Part of the pathway for acetamido sugar biosynthesis in bacteria and archaea.-!-The enzyme from several bacteria (e.g., Escherichia coli, Bacillus subtilis and Haemophilus influenzae) has been shown to be bifunctional and also to possess the activity of EC 2.3.1.157.-!-The enzyme from plants and animals is also active toward N-acetyl- alpha-D-galactosamine 1-phosphate (cf. EC 2.7.7.83), while the bacterial enzyme shows low activity toward that substrate. | The enzyme from plants and animals also has activity toward N-acetyl- alpha-D-glucosamine 1-phosphate (cf. EC 2.7.7.23). H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine. | H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-galactosamine. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLDP(Pro->Val)YK MGYG000000029_00187 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides finegoldii|m__MGYG000000029 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6185545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLDSPFEEGTIGK MGYG000004735_00112 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,2495D@186801|Clostridia,3XZPT@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 oligoendopeptidase, M3 family 1.0 pz-A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Peptidase_M3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLDVYADEPATNK MGYG000002794_01059;MGYG000001733_00763;MGYG000004487_01856;MGYG000004475_00746;MGYG000003819_01257;MGYG000001824_00899;MGYG000002156_00958 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,2N6Y5@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 EH 1.0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 1395757 731545 575840 0 555835 0 1409944 0 0 0 0 0 0 0 0 0 0 0 0 912469 0 0 0 0 0 951506 888816 0 0 0 0 460246 802269 864834 0 988548 610082 761355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265843 1062177 1118688 0 568964 0 447520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816592 958679 434950 0 518134 0 1179357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLDVYK MGYG000001310_00612;MGYG000000249_02372;MGYG000000251_02115;MGYG000002286_00349 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1318326 0 1664013 0 1672865 3560638 1593737 1754063 1481085 1433351 1679033 5950367 2399995 291988 0 2155252 1212806 4901454 0 441134 0 4174165 4722583 1843842 0 1840982 1149997 4627490 1270647 1517845 1801056 357850 1649145 536948 1584283 261051 1621060 1955043 2451367 0 2402168 0 2314439 1127256 2143422 1884664 1822734 1567436 1581176 4426467 2209522 1351646 0 1739094 5875143 5946288 0 2186520 0 838761 5876919 1738542 0 1823491 2048124 5086359 2426370 0 3951205 2057989 2612735 2534952 2395945 2577822 2141084 2981113 3920973 0 4105598 0 3124948 3691167 3830451 4113812 4468836 4157148 2785991 3114843 3038026 3918071 0 3736343 3832858 4071101 0 3021172 0 3437300 6090738 3792972 0 3808630 3603707 7403788 4466800 4195250 3398265 3675759 3042940 4234062 4156508 3668163 3459000 3440816 2064872 0 3773854 0 2627363 2852230 2731094 3149218 2682975 3318958 2984771 2582845 2478033 2277061 0 2115957 3114459 0 0 489588 0 2448369 8645991 2929562 0 3136388 2153262 0 2437431 2730977 2229499 3148235 497580 4000343 3257230 707893 2619018 3595941 383335 0 712233 0 274938 356862 556667 537282 214383 310527 207534 1033754 128856 582978 0 451098 507626 2016721 0 386942 0 190849 2807817 230605 0 0 492140 3661944 260223 0 284790 425828 1003314 491607 146207 195714 191308 580938 -AAGLEAAK MGYG000002469_01727;MGYG000003383_00235;MGYG000001292_02316;MGYG000002469_00420;MGYG000003683_01099 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria,4CZDH@85004|Bifidobacteriales 0.8 201174|Actinobacteria 1.0 G 0.8 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate 0.8 rpiA 0.8 - 0.8 5.3.1.6 0.8 ko:K01807 0.8 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.8 M00004,M00007,M00165,M00167,M00580 0.8 R01056 0.8 RC00434 0.8 ko00000,ko00001,ko00002,ko01000 0.8 - 1.0 - 1.0 - 1.0 Rib_5-P_isom_A 0.8 - 1.0 - 1.0 - 1.0 - 1.0 ribose-5-phosphate isomerase. ribose phosphate isomerase. Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate. aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate. 0.8 0.8 0.8 0.8 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.8 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1675501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1430391 0 0 0 0 1214385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2201448 0 0 0 0 702124 0 0 0 0 1590695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLENLK MGYG000001652_01650 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__V9D3004|s__V9D3004 sp002349525|m__MGYG000001652 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,27I98@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1678694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3452628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802757 0 0 0 0 0 0 -AAGLLAK MGYG000004763_00962 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG0578@1|root,COG0578@2|Bacteria,4NJ15@976|Bacteroidetes,2FR3V@200643|Bacteroidia,4AQ69@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,DAO_C,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLLDNPVK MGYG000004468_01043;MGYG000001337_02760;MGYG000002108_01347;MGYG000000243_01631;MGYG000003493_02044;MGYG000000074_00316;MGYG000002478_03834;MGYG000001789_00906;MGYG000003202_00717 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,2FM07@200643|Bacteroidia,4AM56@815|Bacteroidaceae 0.4444444444444444 976|Bacteroidetes 1.0 E 1.0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism 1.0 glyA 1.0 - 1.0 2.1.2.1 1.0 ko:K00600 1.0 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 1.0 M00140,M00141,M00346,M00532 1.0 R00945,R09099 1.0 RC00022,RC00112,RC01583,RC02958 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 SHMT 1.0 - 1.0 - 1.0 - 1.0 GH13_11 0.8888888888888888 glycine hydroxymethyltransferase. threonine aldolase. Also catalyzes the reaction of glycine with acetaldehyde to form L-threonine, and with 4-trimethylammoniobutanal to form 3-hydroxy- N(6),N(6),N(6)-trimethyl-L-lysine. (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)- 5,6,7,8-tetrahydrofolate + L-serine. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Metabolic pathways;Antifolate resistance;One carbon pool by folate;Glycine, serine and threonine metabolism;Cyanoamino acid metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 1575859 0 1924110 1268599 0 0 1574685 1375213 1183593 1085921 1106991 1437680 0 1164739 0 1495566 0 1189786 1485762 1425291 0 0 1459581 0 0 1186535 0 1422584 0 1394394 1610264 0 1707756 1356670 0 0 1377037 1792113 1443467 0 1318933 1262448 0 0 1130757 0 1514862 998771 1304427 1125731 0 1130430 0 1212157 0 1247639 1130030 1099588 0 0 2097264 0 0 1137377 0 1926114 0 1281749 828869 0 1479504 1258615 0 0 1355501 1210267 372890 0 209592 755226 0 0 580775 362353 679328 383196 562849 455032 0 635704 0 508440 0 791886 440384 516067 0 0 665195 0 0 425366 0 645506 0 600242 688996 0 456595 542651 0 0 355471 737684 891612 0 408811 456599 0 0 629365 660518 0 542404 492454 398621 0 585567 0 755202 0 188438 626152 408510 0 0 278402 0 0 361874 0 336016 0 373673 199790 0 483740 340413 0 0 598132 325334 873582 0 1142887 864534 0 0 796384 1118256 971897 481375 580197 813046 0 523278 0 957024 0 1596465 1247289 1152419 0 0 1520205 0 0 801590 0 1821421 0 1205192 912917 0 563068 985931 0 0 712872 857674 -AAGLLER MGYG000004735_02408 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,21ZF0@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 - 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLLGK MGYG000000098_02464 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides bouchesdurhonensis|m__MGYG000000098 1.0 COG0578@1|root,COG0578@2|Bacteria,4NJ15@976|Bacteroidetes,2FR3V@200643|Bacteroidia,4AQ69@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,DAO_C,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 643257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 598638 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLLQR MGYG000002494_03827;MGYG000002515_00885;MGYG000002534_03362;MGYG000003022_01866 class d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria 1.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RUEK@1236|Gammaproteobacteria,3XMZ8@561|Escherichia 0.75 1236|Gammaproteobacteria 0.75 C 1.0 Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor 0.75 glpA 0.75 GO:0000166,GO:0003674,GO:0003824,GO:0004368,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006072,GO:0006091,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016901,GO:0019637,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046168,GO:0046434,GO:0048037,GO:0050660,GO:0050662,GO:0052646,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901136,GO:1901265,GO:1901363,GO:1901575 0.75 1.1.5.3 0.75 ko:K00111 0.75 ko00564,ko01110,map00564,map01110 0.75 - 1.0 R00848 0.75 RC00029 0.75 ko00000,ko00001,ko01000 0.75 - 1.0 - 1.0 iSDY_1059.SDY_2436 0.75 DAO,Fer2_BFD 0.75 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 0.75 0.75 0.75 0.75 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1538572 0 0 0 0 1935910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLPVDGK MGYG000000182_01779 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Mitsuokella|s__Mitsuokella sp003458855|m__MGYG000000182 1.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H21V@909932|Negativicutes 1.0 909932|Negativicutes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 - 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 173395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 118353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 716039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLQVNM(Oxidation)VSAQPGSGSNFR MGYG000000243_01882 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4AWF7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLQVNMVSAQPGSGSNFR MGYG000000243_01882 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4AWF7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 801552 0 638161 0 0 701500 0 0 0 0 0 594370 0 0 683541 751910 0 0 0 0 0 0 0 0 0 0 0 0 0 824237 0 0 0 0 572433 0 0 0 0 0 267536 0 0 174424 0 0 0 0 0 107969 0 0 341950 269260 0 0 0 0 0 0 0 0 0 0 0 0 0 535863 0 0 0 0 321716 0 0 0 346693 0 0 0 0 0 0 0 0 0 0 441662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 206299 0 0 0 0 0 0 0 0 0 0 194337 0 0 0 0 0 0 0 0 0 0 0 512020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLSFGEAK MGYG000002494_00473 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,3WVJB@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 O 1.0 SurA N-terminal domain 1.0 ppiD 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 1.0 5.2.1.8 1.0 ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 458113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1166745 1218392 0 938138 1446670 1058830 0 0 0 0 0 0 0 0 0 0 0 1526783 0 1290675 1675718 0 1305148 1228944 0 0 0 1869242 1207795 0 828931 1166767 0 0 0 0 1110613 0 531281 0 0 0 0 506551 0 0 0 0 0 0 0 0 0 0 0 575682 0 495541 508104 0 0 304037 0 0 0 318098 466017 0 539015 285948 0 0 0 0 598890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272291 0 308218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577415 581305 699134 0 0 0 0 0 0 0 0 0 0 0 225812 0 656099 582173 0 373294 627676 0 0 0 758582 0 0 860766 901224 0 0 0 0 597186 -AAGLSVTPTTAAPSAPK MGYG000001302.1_01546 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG4770@1|root,COG4770@2|Bacteria,4NSWV@976|Bacteroidetes,2FRYI@200643|Bacteroidia,22UGJ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Biotin-requiring enzyme 1.0 mmdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGLYK MGYG000000053_00539;MGYG000000222_02092;MGYG000000074_02214;MGYG000001302.1_01771;MGYG000002082_02095;MGYG000001783_01717;MGYG000002517_02258;MGYG000002478_01473;MGYG000004797_02540;MGYG000002438_03363;MGYG000001489_04121 domain d__Bacteria 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FN0E@200643|Bacteroidia,22WXW@171551|Porphyromonadaceae 0.45454545454545453 976|Bacteroidetes 0.9090909090909091 H 0.9090909090909091 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA 0.9090909090909091 kbl 0.9090909090909091 - 1.0 2.3.1.29 0.9090909090909091 ko:K00639 0.9090909090909091 ko00260,map00260 0.9090909090909091 - 0.9090909090909091 R00371 0.9090909090909091 RC00004,RC00394 0.9090909090909091 ko00000,ko00001,ko01000,ko01007 0.9090909090909091 - 1.0 - 1.0 - 1.0 Aminotran_1_2 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 0.9090909090909091 glycine C-acetyltransferase. 2-amino-3-ketobutyrate coenzyme A ligase. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Glycine, serine and threonine metabolism 0.9090909090909091 none 1.0 493330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 910216 833137 0 778435 789345 1092086 0 0 0 0 0 918533 0 0 663470 394714 935464 0 0 0 0 0 0 0 826966 689638 0 0 0 0 0 0 0 0 1039922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163815 0 457651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1043674 710294 1416554 1761535 0 1233507 1079162 0 1081633 1161092 1617711 0 0 0 983205 1041729 0 1033916 0 1687750 0 0 1283219 964345 1217361 0 0 0 0 1014851 530248 921114 0 2385198 1101446 0 0 -AAGLYKNER MGYG000000222_02092;MGYG000001302.1_01771;MGYG000001783_01717;MGYG000002478_01473;MGYG000004797_02540;MGYG000002438_03363;MGYG000003701_03757;MGYG000001489_04121;MGYG000000174_02073 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FN0E@200643|Bacteroidia,22WXW@171551|Porphyromonadaceae 0.7777777777777778 976|Bacteroidetes 1.0 H 1.0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA 1.0 kbl 1.0 - 1.0 2.3.1.29 1.0 ko:K00639 1.0 ko00260,map00260 1.0 - 1.0 R00371 1.0 RC00004,RC00394 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine C-acetyltransferase. 2-amino-3-ketobutyrate coenzyme A ligase. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism 1.0 none 1.0 693771 0 1159963 817048 1253953 859647 0 331119 805410 0 878420 858497 1238120 1350394 719175 1076195 840310 1355054 1250969 709422 1044392 1228533 728896 1270859 690413 891999 940418 839319 0 803964 1123282 1142093 1217431 377178 956273 783708 749560 1245286 318719 0 726938 556367 549613 440555 0 384561 299325 0 520103 410006 421028 329370 707453 371729 317992 940578 265789 126067 518650 621335 183344 447162 438634 412408 191619 133081 0 313538 445501 619518 625362 510222 531022 533816 478323 399753 77114 0 485047 562801 658909 737171 0 212233 530757 0 492864 613311 324691 296444 291598 303626 291312 222556 589587 503647 598594 453057 693434 846349 505914 187877 237582 723944 0 246749 700367 445989 357612 158421 267022 691913 454065 421283 365261 0 134960 469226 153895 409517 0 276482 174321 0 355993 751901 114144 464099 524524 156881 173631 276967 502051 449791 355940 194840 350928 413859 353795 469296 324946 324121 0 386489 362305 524586 277351 350034 263060 358435 117772 202985 651859 0 712919 1154453 1587820 773195 0 526410 797630 0 965333 1176364 1282970 1002260 725341 645029 558567 474805 664783 732651 511113 524607 364991 1065917 943709 974227 663804 464194 0 1204208 1064798 1029603 899684 787496 937028 995455 1810899 694476 -AAGMAAESAAR MGYG000003683_01113;MGYG000003730_00226;MGYG000002469_01744;MGYG000001292_02337;MGYG000003383_00196 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4D0PJ@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472397 0 0 0 0 992005 0 0 0 0 643097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9950223 0 0 0 0 4101899 0 0 0 0 7145320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2133312 0 0 0 0 1267396 0 0 0 0 1386165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1221668 0 0 0 0 1468305 0 0 0 0 1014882 0 0 0 0 0 0 0 0 0 0 -AAGMISN(Deamidated)DEIAAMKR MGYG000002556_00558 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-279|s__CAG-279 sp000437795|m__MGYG000002556 1.0 COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,2FNRM@200643|Bacteroidia,22WNF@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB,SusF_SusE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 149474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 911280 0 0 0 0 925131 0 0 0 0 821255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGN(Deamidated)NGLWEVTVALK MGYG000002478_01081;MGYG000002560_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 680734 0 0 0 0 772807 0 0 0 0 1189808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGNADIIGVGFDK MGYG000000201_01306 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066145|m__MGYG000000201 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ95@1239|Firmicutes,24AX7@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 PFAM periplasmic binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1195440 0 0 0 0 490467 0 0 0 0 1237357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 274578 0 0 0 0 320621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 970076 0 0 0 0 881496 0 0 0 0 804144 0 0 0 0 0 0 0 0 0 0 -AAGNEADAEVAAK MGYG000001346_03032 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1271@1|root,COG1271@2|Bacteria,4NG7U@976|Bacteroidetes,2FMV6@200643|Bacteroidia,4AK8I@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1271 Cytochrome bd-type quinol oxidase, subunit 1 1.0 cydA 1.0 - 1.0 1.10.3.14 1.0 ko:K00425 1.0 ko00190,ko01100,ko02020,map00190,map01100,map02020 1.0 M00153 1.0 R11325 1.0 RC00061 1.0 ko00000,ko00001,ko00002,ko01000 1.0 3.D.4.3 1.0 - 1.0 - 1.0 Cyt_bd_oxida_I 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ubiquinol oxidase (electrogenic, proton-motive force generating). cytochrome bd-I oxidase. This terminal oxidase enzyme is unable to pump protons but generates a proton motive force by transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water.-!-The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) is 1.-!-The bd-I oxidase from the bacterium Escherichia coli is the predominant respiratory oxygen reductase that functions under microaerophilic conditions in that organism. cf. EC 7.1.1.3.-!-Formerly EC 1.10.3.14. 2 a ubiquinol + 4 H(+)(in) + O2(in) = 2 a ubiquinone + 4 H(+)(out) + 2 H2O(in). 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 288765 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 749340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGNN(Deamidated)GLWEVTVALK MGYG000002478_01081;MGYG000002560_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2991365 3922355 2911221 3965537 4131968 0 2864439 0 3158035 2934223 0 0 4974419 2659980 0 2391833 2922339 2118524 0 4119083 3021857 0 3107763 0 2881854 0 3360565 4474605 3321806 0 0 6078024 3458627 0 3966244 0 3404145 3493831 0 0 169802 0 0 0 282735 0 344219 4825965 0 0 0 585917 0 0 0 0 277455 0 0 0 0 0 0 402912 0 143985 117268 0 0 314946 0 0 0 0 0 261526 461972 359110 548654 109047 884558 0 618148 0 0 947479 0 0 1434628 590483 0 1011151 416776 432646 1198241 1018617 702343 0 614034 0 587731 1289602 934609 1134424 577527 0 0 1198033 716347 0 1003893 0 1031830 528790 439326 214314 0 158649 0 0 97003 0 0 428711 0 0 239019 238586 0 116851 0 175008 0 0 0 0 0 0 304506 261620 248130 0 198686 0 0 0 239083 0 0 0 200167 0 0 0 0 200285 0 0 0 0 4845441 0 0 0 0 26513053 0 7771145 2685387 0 0 0 0 0 14628739 0 0 0 0 5537924 0 0 0 0 0 0 0 0 57440069 0 -AAGNNGLW(Dioxidation)EVTVALK MGYG000002478_01081;MGYG000002560_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 587248 0 0 0 0 0 0 0 0 0 0 1267686 1184348 0 0 649626 888168 561293 460847 0 0 0 293684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360700 0 0 0 0 242754 0 257243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 202170 0 0 0 0 0 0 0 0 0 0 0 210275 0 0 0 268979 0 307340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGNNGLW(Trp->Kynurenin)EVTVALK MGYG000002478_01081;MGYG000002560_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1279295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1188572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGNNGLWEVTVALK MGYG000002478_01081;MGYG000002560_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 3381228 3838210 3720044 5679295 5641627 3365210 4784967 0 4555335 3558057 0 0 5713475 2863175 0 3803780 4468066 2472837 3324055 3404349 3788452 3487579 3797702 4197556 3110513 3498824 4239405 3786765 4814263 6136921 0 4013768 4054349 0 4778514 4478441 4494995 3979617 0 633042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300965 0 0 0 0 0 0 0 0 0 0 0 0 0 1102820 761308 479351 766688 1314492 1048363 872133 0 364296 896778 0 0 1259838 994661 0 1349832 729317 1042983 1224346 1367218 1318277 874781 1137204 694558 901323 1552030 1236108 1395231 1114205 1100442 0 889068 1175963 0 1336524 1000205 323406 622238 48394 496118 0 69133 56511 0 0 0 61917 42037 0 0 0 126579 0 0 94671 0 60985 73253 0 0 0 0 70663 126690 0 0 0 0 0 309808 0 0 59805 137577 0 138334 0 0 0 0 0 0 222344 0 0 0 0 0 0 0 0 41084 0 268658 0 0 0 0 388345 0 0 0 0 0 0 0 0 375902 189931 0 0 0 0 164686 -AAGNQAELDEK MGYG000000074_00484 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0111@1|root,COG0111@2|Bacteria,4PMZ0@976|Bacteroidetes,2G0M0@200643|Bacteroidia,22V4Q@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 - 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGPAAAG(Gly->Gln)AAAEEK MGYG000003202_00136 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__UBA3263|s__UBA3263 sp900759865|m__MGYG000003202 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGPAAAGAAAAEEK MGYG000001364_00555;MGYG000001306_02652;MGYG000004479_00848;MGYG000003693_02794;MGYG000000043_02878 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 324123 0 151489 0 240982 0 0 0 0 0 231280 0 0 0 0 0 0 232984 0 249002 0 0 386194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 866877 0 904194 1068061 1002254 0 0 1027886 1242256 0 1709854 773620 749771 1003677 815424 0 0 6863899 0 619614 0 0 0 0 0 1027384 858548 0 0 0 0 0 845388 0 0 859345 0 0 0 0 836694 504531 0 0 0 602735 897402 0 0 545864 573619 551485 622683 0 0 279950 0 0 0 0 257818 0 0 745126 0 169672 0 0 0 0 0 0 0 0 0 685448 906882 0 0 0 191088 0 0 266528 0 0 0 278855 0 187249 706687 0 0 990545 0 0 0 0 1003663 0 0 795202 162975 627761 0 0 0 0 887482 0 0 0 1019297 114872 0 0 369404 423561 229386 0 0 354566 274033 0 530795 0 517979 0 105853 0 0 2136485 0 231866 0 0 2188193 0 0 219643 0 1441731 0 0 0 0 456125 0 0 445665 155990 370789 -AAGPAAAGAAAEEK MGYG000003202_00136 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__UBA3263|s__UBA3263 sp900759865|m__MGYG000003202 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGPAAAGAAAEEKTSFDVVLK MGYG000003202_00136 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__UBA3263|s__UBA3263 sp900759865|m__MGYG000003202 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1553914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212805 0 0 0 0 0 0 0 0 282302 0 0 227442 0 0 0 0 0 0 0 770960 0 0 0 0 0 0 0 0 0 0 749606 0 0 0 0 0 0 0 786330 0 0 0 0 0 1021276 0 0 0 0 0 594049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 758090 0 0 576697 0 0 0 0 0 0 340568 0 0 0 466537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1215674 0 901029 0 0 1235197 0 1312417 792353 834248 1249407 0 0 0 0 0 0 0 2027428 1027217 1726933 0 -AAGPAAAGAAVEEK MGYG000001666_00327 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-873|s__|m__MGYG000001666 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 2987489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1810530 0 0 0 0 0 0 0 2037302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 930996 0 0 0 0 1738221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGPAAAGAVAEEK MGYG000002820_00704 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Negativicoccaceae|g__Negativicoccus|s__Negativicoccus sp900556745|m__MGYG000002820 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4H4X8@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1795220 1520827 0 0 0 0 0 0 1466737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1299142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGPAAAGGAAAEEK MGYG000003363_00507 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900766195|m__MGYG000003363 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGPAAAGGAAAEEKTSFDVVLK MGYG000003363_00507 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900766195|m__MGYG000003363 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 410268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 898761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGPAAFVTK MGYG000002517_01802 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 O-acetylhomoserine 1.0 metY 1.0 - 1.0 2.5.1.49 1.0 ko:K01740 1.0 ko00270,ko01100,map00270,map01100 1.0 - 1.0 R01287,R04859 1.0 RC00020,RC02821,RC02848 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism;Metabolic pathways 1.0 none 1.0 976391 0 383715 0 152559 187488 0 307899 0 0 0 0 0 353201 432165 0 212210 0 0 384966 0 574287 0 126469 0 0 0 0 0 276313 0 0 0 267777 498587 867428 788953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7651053 0 0 8226092 383432 0 1678052 2004819 4200489 298809 0 0 0 7012608 5774438 0 451983 0 0 5209493 0 0 0 0 5554507 4546661 8516476 0 0 5435445 0 0 0 2996912 3853193 6819165 3671124 0 671010 0 1342644 0 1047072 1701867 736868 0 619946 831513 0 0 0 745114 998288 0 1790751 0 0 602177 0 1428059 0 1309055 618983 435467 897618 0 0 0 621017 0 0 726290 298042 867620 922996 1277541 -AAGPAAFVTR MGYG000000133_01810 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 9.98 1.0 metY 1.0 - 1.0 2.5.1.49 1.0 ko:K01740 1.0 ko00270,ko01100,map00270,map01100 1.0 - 1.0 R01287,R04859 1.0 RC00020,RC02821,RC02848 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism;Metabolic pathways 1.0 none 1.0 0 768533 0 0 0 1352938 0 0 0 0 0 783780 0 0 0 0 0 0 0 0 397482 1180528 0 250819 0 0 0 0 0 0 401182 392005 0 0 0 0 0 882509 0 0 0 0 0 0 0 0 0 0 0 168188 0 0 0 0 0 0 0 0 251894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168535 0 0 0 0 0 665266 0 0 0 0 0 0 0 0 285723 505136 0 610593 0 0 0 0 0 0 0 390112 678364 0 0 0 0 0 0 3136612 2837590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331475 0 371369 0 0 0 0 0 0 0 0 1006030 0 0 0 0 0 0 14340032 11031785 0 0 6842466 0 0 0 0 0 9472391 0 0 0 0 0 0 0 0 10953280 12166736 0 7207268 0 0 0 0 0 0 9226452 6539338 13732583 0 0 0 0 7830548 -AAGPAAGA(Ala->Gln)AAAEEK MGYG000004797_04276;MGYG000001345_04691;MGYG000001337_03901;MGYG000002478_00807;MGYG000000236_01800 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2604254 0 0 0 0 0 0 0 0 0 0 0 0 -AAGPAAGAAAAEEK MGYG000004797_04276;MGYG000001345_04691;MGYG000001337_03901;MGYG000002478_00807;MGYG000000236_01800 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 9848163 7377080 4488914 0 8967043 0 10224312 5281392 0 6012387 0 0 0 8584785 6611572 18677597 7745287 0 0 7614749 0 6941364 12467599 0 6380124 9178943 11226629 0 8211916 0 0 0 0 5830533 0 9340575 7746459 5691951 9822225 6300020 10393019 9578382 12989594 8793647 6705831 9747477 0 9143065 0 8410689 0 11496430 8598836 17334347 8176552 0 10976469 9426399 8130149 8101531 10094460 0 8739755 9662427 9479984 8096801 8214289 9682066 6836733 8906733 9180638 6592074 0 8931518 0 7900052 3014450 2771700 6498577 3403147 8560910 5568791 4885225 2162068 5652534 3565965 5866100 3558388 8465158 4071975 3760924 7301977 3258546 9548847 2947312 3412623 2910159 0 7897361 4516285 3452298 3825204 3209091 5625665 3929588 2911362 5044653 3200350 2865591 1610592 2865610 5757661 4409078 5353700 0 4356408 4181661 3893043 5056657 4354803 4959347 4099916 4571465 5754349 8535909 4830968 7402049 4477018 4099786 7220787 4469745 5153146 4226250 4571514 3468223 4049091 3043786 4898343 5117662 5631408 5226218 3599505 0 3916754 4372828 4524091 4483425 2819334 5199992 6240674 5124708 3819544 6255970 3214599 4788526 4627975 0 7964030 3886316 8384632 8611449 3860676 6598007 5162470 16794757 5326796 5485519 14303044 5599589 20082997 7595990 9623855 0 0 17952388 8848084 8922241 0 5980229 13098897 6350339 3751579 5259256 3411994 4432373 8258598 10898350 0 0 5909674 -AAGPAAGAAAAEEKTSFDVVLK MGYG000004797_04276;MGYG000001345_04691;MGYG000002478_00807 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1584254 0 0 0 3496988 1928574 0 0 0 1459882 3875730 2141839 3590874 1555590 1275042 2985238 2011764 1105619 1475029 0 1621616 1357144 1469476 0 1391009 2318343 1807716 0 1803751 0 3580884 0 1942449 0 2129381 1457752 1819927 1825681 371948 315396 375983 486902 1261167 494090 256779 0 222377 465448 0 246036 1417819 395199 713468 1345060 552053 0 337415 315350 456861 735173 0 374365 224618 341130 422692 0 383723 0 391138 734289 328049 0 449221 449686 303644 497068 653423 1456464 1637647 970624 2178431 1645906 1187239 0 1292055 938130 1651631 1760257 1806576 837077 1009905 1830188 0 1078309 1890874 844466 882842 735462 811557 1318936 937437 1668028 0 1050548 938972 0 1185805 984398 0 0 1144555 1234678 1029710 1478460 0 456520 654594 458939 487519 0 530875 0 435546 445583 862344 735948 595935 449319 474809 611264 578828 470925 334214 360880 690692 463708 352367 360902 554432 815122 427441 439189 301068 0 288507 479202 448122 0 640300 563130 634541 339705 1291802 951595 971223 969212 0 1245916 655052 0 910277 975606 1313720 804677 4311375 1177945 1234021 1861743 534969 0 0 957686 178971 0 490935 2030950 0 0 582273 460563 2441147 0 1612805 933065 741384 0 0 0 1384486 1652474 -AAGPAAGAAAEEEKSAFDVVLK MGYG000002556_01325 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-279|s__CAG-279 sp000437795|m__MGYG000002556 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436669 0 0 0 0 325642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 961962 0 0 0 0 921796 0 0 0 0 772593 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165850 0 0 0 0 0 0 0 0 0 0 -AAGPAAGAAAV(Val->Ala)EEK MGYG000000098_02010;MGYG000000054_03940;MGYG000003312_01245;MGYG000000196_03981 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGPAAGAAAVEEK MGYG000000098_02010;MGYG000000054_03940;MGYG000003312_01245;MGYG000000196_03981 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 6511706 5803885 3889985 6035743 4681185 4872985 0 4432853 6051459 0 2932378 0 3685251 5224957 5545346 5411418 5371414 1033810 4292709 5215787 6102107 3997915 1857311 5439714 4315511 6567749 5298875 1305407 4748504 0 5396392 6629416 4390640 6255309 5231200 6304808 0 3930348 3437822 2093033 3743163 3605512 3216151 2788964 2916852 3481129 3601924 3678554 3011491 2959529 2665179 3794908 3151006 2574484 2829666 0 0 2882477 2832518 2989338 412748 2425586 2825414 3187080 2937096 0 3560324 3018888 2797144 3916248 3311064 3532436 2174894 3387888 3807201 3224180 0 0 2327371 2141548 2998404 2152763 2997300 2473622 0 1495481 0 1671893 1531339 2412156 2233547 1883192 2005404 911211 0 2076841 2339070 1398608 657698 1931772 2180512 2374841 2549703 322122 2315565 1668409 2154202 1243348 1299214 0 1611204 3651962 0 0 1630592 1327689 0 0 1320465 1572819 0 2072924 2011171 1570086 1430992 0 1752631 0 1545110 1964031 1710290 935063 1612391 1536340 1596011 1724909 504880 1426450 1979259 2547875 1850420 954777 1043548 1247265 775859 1542397 1719748 2633862 1620654 1908713 1963309 1139871 2178769 1044541 986381 1611303 1620349 0 1292824 2419399 2586658 1816322 1307521 896408 1758137 1019187 1945057 1370710 1452151 427797 1684353 2297209 1138826 1177497 348005 1619285 1424790 2382910 2008631 0 1029412 1909966 856204 1616195 983947 2963313 1870529 2067732 2228262 1625735 -AAGPAAGAGEAAAEK MGYG000004517_00743 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__UBA5884|s__|m__MGYG000004517 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGPAAGGAAAAEEK MGYG000002080_00533;MGYG000000243_01981;MGYG000002291_02265;MGYG000001056_00099;MGYG000000272_00853;MGYG000003697_01479;MGYG000002293_00514;MGYG000002455_03891;MGYG000002603_01776 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 8339751 8305973 17124583 7836371 10724049 7097901 10178412 7269974 7793522 5424743 9830072 8884817 11880778 7056820 6868464 12247898 7428509 6322499 6499310 6646826 6928918 7065309 6899151 10137374 0 6423961 7874547 6304508 7201200 7370752 14715387 6464910 18732511 9644746 7054571 10173896 7601945 18188753 7142641 4166012 0 7415696 6179798 0 6502660 0 7746737 7931363 0 9770356 6894695 8485158 6730947 8257012 6632626 3302463 0 6848784 8046510 5936132 5405917 4620594 7854518 0 7599178 4789035 4821181 7388666 3904946 6725571 6241541 5158869 0 6309591 8118477 6716896 5300421 4153639 6741987 6449184 0 0 8787166 4393576 8644959 5279516 15337761 6907439 8418664 7754272 5652181 8499357 5311087 0 4862464 5951861 5885543 5413921 9472268 6346488 5565493 6497865 5170601 8337855 6942271 5691492 7650501 3825765 4119427 2625612 6416786 10036946 0 7155617 10754593 11162963 34148882 7716768 21954283 25870176 10062793 13114122 12399617 11280141 38462212 15329959 25311819 8336017 10234113 21954358 12376841 35790544 8633671 8843935 7356181 44811595 0 33615893 13381070 14022540 11903542 21680984 12185932 7322519 13794625 14908966 25267879 12726283 10396513 13929539 13053688 0 1960821 1275283 1766524 1418068 2455978 1830222 1967167 3273571 2373522 1501587 8841065 2048388 2810107 2153279 1751458 2118856 1548601 6501969 2644168 0 1710281 1647804 6205578 2222244 3248699 0 2068613 6293913 1091983 0 1957130 0 0 3377654 3662191 2276716 2481652 0 -AAGPAAGGAAAAEEKTSFDVVLK MGYG000000243_01981 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 328550 0 6842524 1280759 0 1597583 1311486 1613783 1522217 0 0 1967325 0 1474198 1652171 1514962 1684244 945974 349076 0 1257847 1362977 1141663 2070960 1215249 1579327 1400249 1304905 1419075 1659386 4929559 2420288 0 1429738 1547881 1185138 1521940 5024079 259893 224740 323454 245106 500681 249975 400473 363194 233837 0 339597 410828 437791 287704 595345 397720 410391 0 271432 0 266147 441962 0 183667 329391 351661 380732 0 266323 261075 231618 372043 248721 327280 423254 318556 266345 309017 714727 881540 950091 1129564 1994033 1313391 1027092 837438 877227 0 2466718 1137085 1697724 1013534 715139 1450380 1109977 948031 817291 0 753256 561098 799379 1228918 765823 1051673 909279 814428 1004961 774654 1339240 814800 675803 534419 1017394 1109869 908921 1139910 421392 253955 455260 441116 400446 342041 382075 541223 417225 0 599122 448673 585914 409153 511658 279143 473740 212956 484700 0 612999 289759 0 351344 419662 574525 424541 0 259942 331373 298661 583037 315750 707666 790524 537206 348366 252688 200436 0 0 253818 335527 307904 0 0 261449 0 1029890 0 443244 0 275008 0 0 0 0 0 0 159490 0 245032 0 202767 0 0 332334 193919 281597 118969 0 244104 337036 0 261774 237349 -AAGPASYGMTDTLGR MGYG000000142_02731;MGYG000000215_01600;MGYG000000127_05084;MGYG000001496_01287;MGYG000004762_01356;MGYG000004733_02764;MGYG000000212_00326 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.8571428571428571 186801|Clostridia 0.8571428571428571 S 1.0 Psort location Cytoplasmic, score 8.87 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 785384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 622549 0 0 0 0 0 0 0 0 0 0 0 0 0 647107 779306 0 0 0 815439 0 0 621019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362404 0 0 0 0 0 0 0 0 0 0 0 0 0 719127 427302 0 0 0 437284 0 0 1570239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1348771 0 0 0 0 0 0 0 0 0 0 0 0 0 1574303 1686778 0 0 0 1554746 0 0 1251890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521672 0 0 0 0 0 0 0 0 0 0 0 0 0 670757 835269 0 0 0 785008 0 0 743651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 659427 0 0 0 0 0 0 0 0 0 0 0 0 0 1020633 808283 0 0 0 942702 -AAGPASYGMTDTMGR MGYG000000118_02684;MGYG000000028_01055;MGYG000004482_01421;MGYG000003589_01350;MGYG000004604_01207;MGYG000000179_04738;MGYG000001415_02505;MGYG000002528_00119;MGYG000000515_00648;MGYG000000269_00015;MGYG000000205_02543;MGYG000004594_01436;MGYG000002218_00562;MGYG000000262_01832;MGYG000004517_01958;MGYG000001400_01185;MGYG000002517_01686;MGYG000000187_00466;MGYG000004822_01055;MGYG000002492_01963;MGYG000000198_05683;MGYG000001697_00682;MGYG000002438_03055;MGYG000004561_02010;MGYG000004464_00921;MGYG000000245_00061;MGYG000000251_02115;MGYG000001881_00612;MGYG000000312_02568;MGYG000000045_01847;MGYG000002213_00389;MGYG000000233_02118;MGYG000001599_00424;MGYG000004797_02907;MGYG000001423_03082;MGYG000000249_02372;MGYG000001346_01121;MGYG000002148_02635;MGYG000002880_00963;MGYG000002478_02896;MGYG000000223_01510;MGYG000004276_01664 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae 0.14285714285714285 186801|Clostridia 0.5476190476190477 S 0.9285714285714286 Psort location Cytoplasmic, score 0.30952380952380953 - 0.8095238095238095 - 1.0 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 1.0 - 1.0 - 1.0 GGGtGRT 0.9285714285714286 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9285714285714286 0.9285714285714286 0.9285714285714286 0.9285714285714286 0.9285714285714286 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1844059 1298443 2511759 1526577 0 1580807 2256783 1600831 2220101 1554162 1407507 1557086 1952633 1458269 1802682 1407155 1080500 0 1847872 2283628 1509974 1395588 0 1101096 1810980 2012054 1593178 0 1841336 2265160 1162304 0 2010191 2364446 1450139 2509650 2346386 1747826 0 0 0 370694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 659950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGPLFESAK MGYG000002720_01678 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,36DTA@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 PFAM Extracellular ligand-binding receptor 1.0 - 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 1.0 none 1.0 0 0 0 0 0 2821560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGPVEAAEEKTEFDVILK MGYG000002494_02480;MGYG000002506_03692;MGYG000002323_03990;MGYG000002534_04619;MGYG000002477_00982 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,3XPRN@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 720285 497899 706568 571292 379696 813531 896103 496670 838897 701818 348968 487261 185282 674673 757625 97090 577338 0 492281 373709 445134 728220 0 1327026 663716 719879 734014 0 909370 837738 962046 645172 632250 592762 569294 625844 634741 583174 1062921 1028563 1318536 1151039 1385651 2278603 1291085 1073566 1138933 1363625 774646 1524404 579919 1195952 1150865 1273853 2042407 0 1561783 1127800 1121984 3215104 0 1122624 1277614 1021546 1175210 0 913273 1132126 416865 1321032 909001 865541 836516 1016212 802566 768068 860569 910764 1040957 1039832 1474803 2530710 1220283 1110015 964411 958602 1026404 1224254 841543 1083403 797286 857285 2297096 0 900572 1152419 1534433 1374327 0 2309589 707753 483281 1075083 0 1046097 1062688 1771156 1001067 1237739 965405 897426 1224120 658480 1214821 413255 325369 406060 280638 229725 271761 409262 361539 275268 260120 172992 270023 0 211285 256242 207234 323231 0 273035 246453 488507 209031 0 259338 305071 391624 239728 0 185859 338678 185449 305574 300007 877247 642869 489896 316614 314515 0 371167 171144 105340 269850 202106 352998 0 0 211203 379850 351894 173048 212189 0 263553 396369 0 270337 0 0 832744 0 511091 0 0 202494 0 443418 0 466109 432718 282757 259725 589607 240076 251643 0 -AAGQAWIDSVNDAEASK MGYG000003274_00602;MGYG000003266_01692 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,2I995@201174|Actinobacteria,4CUGM@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 271679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 873128 0 0 1454039 0 0 0 0 0 0 0 0 0 0 0 0 0 812553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGQDDILAFR MGYG000003166_00709;MGYG000001300_00361 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3WHAH@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 M18 family aminopeptidase 1.0 apeA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CoaE,Peptidase_M18 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 306465 0 0 503792 352805 0 0 0 0 0 0 0 0 0 811719 730046 728240 519552 0 600003 0 360628 0 0 0 698424 0 0 0 0 402722 0 0 0 0 165253 0 0 472967 0 0 688817 1278593 0 0 0 0 662542 0 0 856066 0 746509 522237 997339 834559 0 365162 358172 541376 1112365 0 0 0 0 0 638737 0 697075 0 0 0 0 440410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 562459 0 0 919089 1092385 0 0 0 0 579612 0 0 529297 0 323765 0 0 962474 0 0 0 533518 590221 0 0 474085 0 0 1391719 0 0 0 0 0 0 0 0 0 324550 0 0 418692 0 0 0 0 0 432456 0 0 0 0 0 1404017 0 0 0 0 1812312 0 266257 0 0 1853028 0 0 0 0 0 0 0 0 0 673307 -AAGQENIFGNQVK MGYG000002517_00959;MGYG000000154_00174 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 950712 0 0 0 0 0 0 0 0 0 0 0 0 0 1060091 0 1209184 0 0 0 0 0 0 0 0 499018 1261186 0 0 0 0 0 0 0 0 0 860023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGQEWLDTFSVGATN(Deamidated)GTATDK MGYG000000133_02129 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1018249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGQEWLDTFSVGATNGTATDK MGYG000000133_02129 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2298974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGQIDC(Carbamidomethyl)SR MGYG000002506_04505;MGYG000002323_00920 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG3477@1|root,COG3477@2|Bacteria,1MV9E@1224|Proteobacteria,1RYHM@1236|Gammaproteobacteria,3XQGU@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 response to acidic pH 1.0 yagU 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016020,GO:0044464,GO:0050896,GO:0071944 1.0 - 1.0 ko:K08996 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF1440 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 880099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1328411 0 1527733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1210054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1098614 0 1259439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2612791 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2119133 0 3096910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1196450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 806985 0 1117288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGSATISAPMPGK MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 360509 0 0 0 0 0 0 0 0 275790 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219601 321780 278389 0 0 0 0 0 1198823 990639 1063347 590494 876619 515698 724312 1697315 934454 884719 496362 797178 389700 721463 854683 495210 1120060 0 835953 1027596 1079437 518755 0 488809 883552 992948 1019195 0 449649 822809 291650 1195230 1342878 931189 1484394 1288379 870441 624528 801460 1246785 1318459 786506 1378894 1737812 1292577 1424722 1391730 889442 1780635 1385879 1133155 1249369 728323 1519362 965593 0 755728 971735 1102042 1048215 0 1262446 967393 766795 749035 0 1093779 957776 1965455 1522913 1198440 1032275 923722 1249512 1215972 1582100 1828648 2363875 3797352 1547653 2285961 2454580 1463956 2499115 1417909 2022791 2610517 2303550 2042227 1729002 1797187 1847530 1420153 0 1683550 1458344 1969479 3541896 0 3100025 1717146 1815033 1492446 0 1805220 1865840 2442767 2617159 4178249 1818031 2742083 2081723 1595783 3156496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGSDLEYEVGTM(Oxidation)IEIPR MGYG000000142_02834;MGYG000001315_01921 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.5 186801|Clostridia 1.0 G 1.0 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 0.5 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGSDLQYEVGTM(Oxidation)IEIPR MGYG000000184_00575;MGYG000000140_01464;MGYG000000171_00241;MGYG000004785_01840;MGYG000001338_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.8 186801|Clostridia 1.0 G 1.0 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 0.8 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 443540 0 0 574774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328432 601172 0 0 0 0 0 0 0 532772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858484 0 0 0 0 0 0 0 0 1056796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 731211 0 0 0 0 0 0 0 714140 0 0 476234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736287 438429 0 0 0 0 0 0 0 573681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525470 0 0 0 0 0 0 0 -AAGSDLQYEVGTMIEIPR MGYG000000184_00575;MGYG000000140_01464;MGYG000000171_00241;MGYG000004785_01840;MGYG000001338_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.8 186801|Clostridia 1.0 G 1.0 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 0.8 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGSDMKYEVGTMIEIPR MGYG000000262_01988;MGYG000002707_01357 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25VEG@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 113421 0 0 71393 168111 0 0 0 0 0 0 0 289795 0 0 0 0 0 0 313729 160627 126757 0 0 0 0 92693 0 91350 255006 0 0 0 0 0 0 0 0 0 0 336683 0 116063 0 0 289730 0 0 0 0 0 200725 0 0 0 0 0 0 0 208717 0 0 253136 0 568062 0 280083 781616 0 0 0 541421 0 586204 0 0 580001 0 595419 540462 670092 0 0 525072 0 0 0 0 545826 532089 681082 0 0 0 0 850902 455308 612799 721098 0 343102 126721 0 0 0 92487 0 0 0 0 0 0 0 0 0 0 0 243216 0 0 0 194375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231672 0 0 0 0 119392 -AAGSDNVMLISDR MGYG000004736_00489;MGYG000002448_00117;MGYG000001225_00663 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Evtepia 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WGYX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 - 1.0 - 1.0 1.1.1.1 1.0 ko:K13954 1.0 ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00623,R00754,R04880,R05233,R05234,R06917,R06927 1.0 RC00050,RC00088,RC00099,RC00116,RC00649 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. aldehyde reductase. Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Fatty acid degradation;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 345939 0 0 0 0 0 0 0 1604755 0 1068317 0 0 1025816 0 0 0 0 1417459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1428966 0 0 0 0 0 0 0 687606 0 1964001 0 0 804866 0 0 0 0 1089669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1782300 0 0 0 0 0 0 0 1202989 0 1404112 0 0 1160461 0 0 0 0 1812109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2390933 0 0 0 0 0 0 0 816357 0 1301349 0 0 1505689 0 0 0 0 1191680 0 0 0 0 0 0 0 0 0 0 -AAGSTVTGGISQLTAGGR MGYG000000301_01629 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900541985|m__MGYG000000301 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia,3XYNF@572511|Blautia 1.0 186801|Clostridia 1.0 S 1.0 Psort location CytoplasmicMembrane, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ABC2_membrane_3,DUF3533 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 760362 0 0 0 0 0 0 929288 0 0 0 0 0 0 0 0 0 0 1012991 0 0 0 0 0 0 0 0 0 0 0 1507580 0 0 0 0 480784 -AAGTDLAGIEK MGYG000000243_00604 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia,4AKN9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 1.0 etfA 1.0 - 1.0 - 1.0 ko:K03522 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055278 0 0 0 0 0 0 1505272 0 0 303781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGTDLSHVVK MGYG000003697_02933;MGYG000002960_01238;MGYG000002293_00704 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,2FT8J@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 endoribonuclease L-PSP 1.0 ridA 1.0 - 1.0 3.5.99.10 1.0 ko:K09022 1.0 - 1.0 - 1.0 R11098,R11099 1.0 RC03275,RC03354 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ribonuc_L-PSP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-iminobutanoate/2-iminopropanoate deaminase. enamine/imine deaminase. This enzyme, which has been found in all species and tissues examined, catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.-!-The reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates. (1) 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+). (2) 2-iminopropanoate + H2O = NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 62477 0 0 0 0 95794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2685601 0 0 0 0 2771183 0 0 0 0 2073089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGTFTTNIVK MGYG000000133_01203 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3XZ0G@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate 1.0 argJ 1.0 - 1.0 2.3.1.1,2.3.1.35 1.0 ko:K00620 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028 1.0 R00259,R02282 1.0 RC00004,RC00064 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ArgJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 amino-acid N-acetyltransferase. | glutamate N-acetyltransferase. N-acetylglutamate synthase. | ornithine transacetylase. Also acts with L-aspartate and, more slowly, with some other amino acids. | Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity. acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate. | L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L- glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 305626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 839263 1606329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1154596 0 0 0 0 0 -AAGTGMIAGGPVR MGYG000002545_01123 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_G|m__MGYG000002545 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3WICZ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2135975 0 0 0 0 3100330 0 0 0 0 2722953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1999236 0 0 0 0 1464105 0 0 0 0 1528542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 986254 0 0 0 0 649686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGTKELGESM(Oxidation)GNLYIAQGQYER MGYG000000196_01844;MGYG000000013_02380;MGYG000000098_00424;MGYG000001345_04496;MGYG000002549_03156;MGYG000003351_03471 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGTKELGESMGN(Deamidated)LYIAQGQYER MGYG000000196_01844;MGYG000000013_02380;MGYG000000098_00424;MGYG000001345_04496;MGYG000002549_03156;MGYG000003351_03471 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 709846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485545 0 0 0 0 462240 0 0 254369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139596 0 0 0 0 280940 0 0 373904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGTKELGESMGNLYIAQGQYER MGYG000000196_01844;MGYG000000013_02380;MGYG000000098_00424;MGYG000001345_04496;MGYG000002549_03156;MGYG000003351_03471 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1317795 0 882480 0 0 1240407 0 0 0 0 0 674526 0 0 0 0 582183 0 0 0 0 0 0 0 0 0 0 0 0 0 796145 0 0 0 0 910904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378579 0 404624 0 0 315085 0 0 0 0 0 207285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222931 0 0 0 0 0 0 0 208258 0 269440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352515 0 0 0 0 419438 0 0 0 0 325069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGTLLK MGYG000002478_02998 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,4ANQH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1239292 0 0 0 0 0 0 1019425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1916077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1232760 0 0 0 0 0 0 778099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618023 0 0 0 0 0 0 431062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2728455 0 0 0 0 0 0 1492727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGTSQMTGK MGYG000002517_02558 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1942@1|root,COG1942@2|Bacteria,1VBFY@1239|Firmicutes,24MXU@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 macrophage migration inhibitory factor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MIF,Tautomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032803 0 0 0 0 0 0 898484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 681014 1006494 0 0 0 0 0 0 0 0 0 0 1147742 0 2620126 0 0 0 0 0 0 1737685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1704067 0 0 0 0 0 0 0 0 0 0 0 2495313 0 -AAGTTLDIVR MGYG000003891_01771 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4H35I@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1222437 0 0 0 0 1259070 0 0 0 0 1114951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289158 0 0 0 0 452622 0 0 0 0 416702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGV(Val->Pro)ESVVFDR MGYG000002834_00456;MGYG000003697_01452;MGYG000001770_00593 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 346361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVAVGAHPGYPDLMGFGR MGYG000001356_00420 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter sp000177015|m__MGYG000001356 1.0 COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,249GD@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Belongs to the UPF0271 (lamB) family 1.0 - 1.0 - 1.0 - 1.0 ko:K07160 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 LamB_YcsF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133556 0 0 0 0 0 0 0 0 0 404798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632471 0 0 0 0 445934 0 0 0 0 344101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 745324 0 0 0 0 222910 0 0 0 0 551280 0 0 0 0 0 0 0 0 0 0 -AAGVDATVQTEALK MGYG000000249_00064 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 1.0 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 GABAergic synapse;Necroptosis;Glyoxylate and dicarboxylate metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2257248 0 0 0 0 1513062 0 0 0 0 1937550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 919284 0 0 0 0 544466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603080 0 0 0 0 0 0 0 0 0 0 -AAGVDITSSERPGTVGSIR MGYG000002478_00199 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478478 0 0 0 0 0 0 0 0 0 0 0 0 1125538 0 0 0 0 1021155 0 0 0 0 799394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670768 0 0 0 0 0 0 0 0 0 0 0 0 2848737 0 0 0 0 2586186 0 0 0 0 2494168 0 0 0 0 0 0 0 0 0 0 -AAGVESVVFDR MGYG000002834_00456;MGYG000003697_01452;MGYG000001770_00593 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 470389 0 0 0 0 0 1335634 0 0 0 0 273122 0 0 0 0 0 310472 0 0 0 0 0 1207842 0 0 0 0 0 0 0 0 724198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 751937 0 6656409 0 2541547 3959721 0 0 1073816 0 5869460 2143664 3433889 0 0 3403670 1045747 8650973 782609 0 1373741 6611776 11009421 0 0 1255818 0 4746795 1493551 0 2471950 2991294 4046652 1803574 0 0 1043764 4711868 799129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128517 0 0 0 0 0 0 0 0 0 0 598503 0 0 0 0 0 0 0 0 0 -AAGVESVVFDRN MGYG000003697_01452 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 415276 0 0 0 0 663756 0 0 0 0 592615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1933072 0 0 0 0 1807864 0 0 0 0 2748156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVESVVFDRN(Deamidated)GYLYHGR MGYG000003697_01452 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4290622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177634 0 183536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 630489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 622820 0 278282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVET(Thr->Ser)VVFDR MGYG000003493_00797 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp002299275|m__MGYG000003493 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3757866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5125417 1374252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVEVEELTK MGYG000002445_02594 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp003024715|m__MGYG000002445 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,21YYA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein-like domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;ABC transporters 1.0 none 1.0 0 0 0 0 1101568 1363573 0 1944711 0 1958685 1755451 0 0 0 1413329 1031901 0 0 0 0 0 1729600 0 1940182 1580887 0 1577939 0 0 0 0 0 0 2679565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524834 0 0 0 0 0 0 0 0 1866183 1939868 0 1530697 0 1998456 1436437 0 0 0 1894669 1447133 0 0 0 0 0 1745247 0 2127111 1568757 0 1471588 0 0 0 0 0 0 2140017 0 0 0 0 0 0 0 0 1017145 764464 0 670456 0 711421 1334636 0 0 0 585620 741341 0 0 0 0 0 891419 0 1116542 529060 0 853182 0 0 0 0 0 0 602422 0 0 0 0 0 0 0 0 0 0 0 495770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVFVQAGGGPLGETTIR MGYG000002438_00957 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22XE6@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463784 0 0 0 738060 541887 0 0 0 651373 0 1650924 0 0 0 0 0 125490 541276 0 1440505 542112 0 383293 0 667100 593185 0 0 1300795 401877 1216204 0 0 0 0 622462 0 0 0 0 0 426800 275984 0 0 0 332714 0 811155 0 0 0 0 0 0 0 0 812839 0 195270 314006 0 0 0 218051 0 564969 314240 389171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384818 0 0 0 1325350 426956 0 0 0 348210 0 2002242 0 0 0 0 0 832468 403666 0 2433392 225973 559712 482632 0 366727 346747 630889 0 3098091 468217 1507872 0 0 0 0 657201 0 -AAGVLFAPERGEDTR MGYG000000243_00236 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG4980@1|root,COG4980@2|Bacteria,4NXMW@976|Bacteroidetes,2FUB7@200643|Bacteroidia,4ARS7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG35214 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 YtxH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 3162532 3813951 8761248 3367860 4214632 3479614 3367327 0 3056225 3204847 3121458 3944162 4813834 3661340 2807465 4584032 3732543 1583465 3944205 2549600 0 2884637 2459117 4823254 0 3934730 3305193 2212187 3126969 3965998 6708232 4880713 6650871 4232265 3508522 3458460 3396726 8761459 574451 437116 737969 248760 1061896 515132 544156 0 824757 1095680 766947 632754 1895488 727281 700890 796033 683691 148893 780359 615143 0 692011 265540 361146 0 571757 571865 183374 629828 629249 339627 755793 769838 651689 648549 668007 739572 710411 1719774 1542261 1993341 1679231 2858916 2701978 1550652 0 1918593 1652238 1965265 1546634 2883773 1587437 1642411 2514675 2754777 1702984 1400606 2030331 0 1103707 1439576 2000366 0 1750280 1669299 1291229 1192980 1307124 2418289 1327937 1367163 541569 1997950 2216200 1669078 1662592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVLFGTAGIK MGYG000002528_03117;MGYG000000146_03297;MGYG000000187_02198;MGYG000000217_00093;MGYG000000251_02450 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,27VWC@189330|Dorea 0.6 186801|Clostridia 1.0 S 1.0 H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1205362 0 0 0 0 963037 0 0 0 0 1003579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVLISYDPNYRPSLWK MGYG000002492_01273;MGYG000000268_02012 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3WGC8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.7.1.4 1.0 ko:K00847 1.0 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 1.0 - 1.0 R00760,R00867,R03920 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructokinase. D-fructokinase. - ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways;Fructose and mannose metabolism;Starch and sucrose metabolism 1.0 none 1.0 0 0 948007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1049351 0 0 0 0 0 0 822016 0 0 1158921 0 2835755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3797253 0 1002504 0 0 0 0 1539020 0 0 1019721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742877 0 2781604 0 0 0 0 1700626 0 0 0 0 166229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298360 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1910003 0 0 0 0 0 0 694374 -AAGVNIFSNSSQPGAYGSR MGYG000002438_03984 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2G0K7@200643|Bacteroidia,231FG@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 449788 0 436654 0 123398 568958 0 0 0 396708 448019 0 266216 0 0 0 784428 333620 0 1045688 287471 681822 0 287808 196891 321585 0 0 0 506282 245988 388978 345033 0 0 0 0 617338 456100 365891 180779 0 318807 981812 0 0 0 441888 383078 1635723 177314 0 0 419241 539256 0 0 193975 1255042 611583 0 0 199560 292606 0 0 0 1023236 532734 749234 389153 0 0 0 350047 337495 175726 183118 0 0 213844 0 0 0 0 0 0 613703 316512 0 0 0 0 0 0 0 536766 0 301496 0 0 322619 0 0 0 434153 285261 0 0 0 0 0 0 0 0 292037 445540 0 286299 546019 0 266473 0 298135 0 414389 0 0 0 0 396230 516035 0 0 862241 691166 428513 0 0 0 0 314395 0 0 266347 0 0 0 0 0 0 0 556612 685688 428749 0 1353529 728345 0 667637 0 636263 772947 2007463 1000983 0 0 1191086 615481 783371 0 738083 2284129 586291 552061 587230 650193 721978 0 600458 0 2052894 641090 1757989 389333 0 0 0 736879 806017 -AAGVPC(Carbamidomethyl)IADGGIHYSGDIAK MGYG000003683_00984;MGYG000000756_00094 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria,4CZ2S@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 383195 0 0 0 0 579810 0 0 0 320718 0 0 0 0 0 546031 254226 0 152295 0 0 0 0 0 0 0 0 0 0 0 0 925597 0 0 0 0 0 0 1356765 0 0 0 0 2760964 0 0 0 660293 1115663 1610660 0 0 0 1754576 917353 0 938164 0 0 0 0 0 0 0 0 0 0 0 0 367345 0 0 0 0 0 0 521371 0 0 0 0 409725 0 0 0 573486 0 0 0 0 0 453249 377761 0 369064 0 0 0 0 0 0 0 0 0 0 0 0 582289 0 0 0 0 0 0 382431 0 0 0 0 298280 0 0 0 975277 0 582127 0 0 0 732432 461640 0 523678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVPLIR MGYG000004885_00927 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotellamassilia|s__|m__MGYG000004885 1.0 COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,2FP6P@200643|Bacteroidia,1WD05@1283313|Alloprevotella 1.0 976|Bacteroidetes 1.0 S 1.0 Predicted permease YjgP/YjgQ family 1.0 - 1.0 - 1.0 - 1.0 ko:K07091 1.0 ko02010,map02010 1.0 M00320 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 1.B.42.1 1.0 - 1.0 - 1.0 YjgP_YjgQ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVPVVVAVNK MGYG000002494_01785 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,3WXXB@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 928107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1370575 0 977640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVPVVYTGPVDR MGYG000003683_01311;MGYG000001292_02510;MGYG000002469_01931 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4CZ2W@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 M 1.0 UDP-galactopyranose mutase 1.0 glf 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 1.0 5.4.99.9 1.0 ko:K01854 1.0 ko00052,ko00520,map00052,map00520 1.0 - 1.0 R00505,R09009 1.0 RC00317,RC02396 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iNJ661.Rv3809c 1.0 GLF,NAD_binding_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 UDP-galactopyranose mutase. - - UDP-alpha-D-galactose = UDP-alpha-D-galactofuranose. 1.0 1.0 1.0 1.0 Galactose metabolism;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1668280 0 0 0 0 876458 0 0 0 0 1157749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424397 0 0 0 0 523069 0 0 0 0 0 0 0 0 0 0 -AAGVQIINSGGPGEAADIR MGYG000002293_00434;MGYG000003697_01963 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FN3Y@200643|Bacteroidia,4AP89@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4364056 0 0 0 0 7122280 0 0 0 0 2344288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVQILNTSGAPGEGAK MGYG000003681_01919;MGYG000004748_01490 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FN3Y@200643|Bacteroidia,4AP89@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2026639 1090645 1782843 2633117 1212567 0 1607653 2447341 2137153 1864532 0 0 0 2356682 2372366 0 1171301 1316387 2969960 2200019 1784138 1912128 2007861 1335360 2066869 2504878 2248740 1523081 1843176 2253150 1202539 1563095 1546048 2023416 2248508 2379276 2362506 1838248 1337699 1679717 2048724 1508462 0 2457559 2222938 1575603 1953823 1775439 0 0 0 1537045 1460148 0 1639861 0 2050484 1265393 0 1435264 5035222 2027075 1419988 1616654 1477545 5113118 1727287 1635126 2242207 1441971 1306841 1599436 1574433 1707421 1531486 1669942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVQILNTSGAPGEGAQ(Gln->Lys) MGYG000000224_01965 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp003545565|m__MGYG000000224 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FN3Y@200643|Bacteroidia,4AP89@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2205014 0 0 0 0 0 0 0 0 1368370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVQVTTPSGVLGSGPQFK MGYG000002438_02058 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,4NDXS@976|Bacteroidetes,2G0KF@200643|Bacteroidia,22XIH@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742103 0 0 0 0 0 0 0 0 1043744 0 0 0 0 0 0 0 0 755240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVSAAALGLAAC(Carbamidomethyl)GGSSSSTASSAASSTAASSTAAK MGYG000001300_01498 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1616270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1926530 0 0 0 0 0 0 0 0 0 0 2033197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1672940 0 -AAGVSAVTTSGAPGSSSSIR MGYG000000781_01055 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900541515|m__MGYG000000781 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4AWF7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1502166 0 0 0 0 1949948 0 0 0 0 1764356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVSC(Carbamidomethyl)VIAETFAR MGYG000002989_00741;MGYG000001777_01812;MGYG000004414_01361;MGYG000000287_00506;MGYG000000562_02520;MGYG000001814_00377;MGYG000000271_00011;MGYG000004839_01241;MGYG000004879_00262;MGYG000002212_01424;MGYG000002966_02377;MGYG000004271_00401;MGYG000001689_05207;MGYG000000002_02744;MGYG000000154_00764;MGYG000004891_01102;MGYG000004869_03018;MGYG000004317_00793;MGYG000000301_00842;MGYG000000806_02465;MGYG000001637_01147;MGYG000000153_00377;MGYG000000050_00293 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia 0.34782608695652173 186801|Clostridia 1.0 E 1.0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate 1.0 leuD 0.9130434782608695 - 1.0 4.2.1.33,4.2.1.35,4.2.1.85 1.0 ko:K01704,ko:K20453 0.9130434782608695 ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230 0.9130434782608695 M00432,M00535 1.0 R03069,R03896,R03898,R03968,R04001,R10170 0.9130434782608695 RC00843,RC00976,RC00977,RC01041,RC01046,RC03072 0.9130434782608695 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 0.9130434782608695 Aconitase_C 0.9130434782608695 - 1.0 - 1.0 - 1.0 - 1.0 3-isopropylmalate dehydratase. | (R)-2-methylmalate dehydratase. | dimethylmaleate hydratase. isopropylmalate isomerase. | citraconate hydratase. Forms part of the leucine-biosynthesis pathway.-!-Brings about the interconversion of the two isomers of isopropylmalate. | Inhibited by oxygen.-!-Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri.-!-Other enzymes involved in this pathway are EC 1.17.5.1, EC 1.3.7.1, EC 3.5.2.18, EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6 and EC 4.1.3.32. (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate. | (3R)-citramalate = 2-methylmaleate + H2O. | (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H2O. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Nicotinate and nicotinamide metabolism;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments;C5-Branched dibasic acid metabolism;Biosynthesis of amino acids 0.9130434782608695 none 1.0 0 0 649702 0 0 0 0 0 0 0 0 0 0 564116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 695359 0 0 0 0 634008 0 0 459104 0 0 0 0 0 0 0 0 0 0 605251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692825 0 0 0 0 472806 0 0 828370 0 0 0 0 0 0 0 0 0 0 549222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775926 0 0 0 0 532043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388925 0 0 0 0 0 0 0 0 0 0 2451449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1832046 0 0 0 0 632280 -AAGVSVITDGGAPGAGATIR MGYG000001337_03660;MGYG000000236_00420 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia,4ANGT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 ko:K21573 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14.6.1 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1117647 0 929376 0 1157942 628187 930353 939486 1110797 860608 0 0 867027 765012 1073900 661354 647404 4294745 921666 0 0 649634 3338190 786407 1107837 1201568 933990 2751268 804020 0 0 0 508230 0 968197 932966 1055693 583162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429234 0 303702 0 0 0 0 0 299656 0 0 0 336319 1443562 0 0 0 0 1288818 0 0 391624 242673 1213319 0 0 0 0 0 0 231613 440838 431900 247623 -AAGVSVQNVSGTFGTAPK MGYG000001461_02869;MGYG000000781_02407;MGYG000003922_00917;MGYG000001306_02322;MGYG000000196_03006;MGYG000001378_00321;MGYG000001345_03478;MGYG000001666_01700;MGYG000003221_02259;MGYG000000196_04938 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AV2B@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 P 0.9 TonB-linked outer membrane protein, SusC RagA family 0.9 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 291780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328643 0 0 958159 0 840578 0 0 0 960306 0 0 0 1399132 0 0 1352280 0 0 0 954736 0 0 0 0 1253394 0 0 824196 972554 1445371 0 0 0 0 822316 0 0 993865 1016264 928934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408115 193845 0 0 0 0 0 0 0 0 0 418034 0 -AAGVTAVSTSGAPGSSSSIR MGYG000001346_02430 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4AWF7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571921 0 0 0 0 555013 0 0 0 0 366380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1160865 0 0 0 0 812147 0 0 0 0 946048 0 0 0 0 0 0 0 0 0 0 -AAGVVSALAQNAR MGYG000003170_00069;MGYG000001410_00795 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella 1.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,4PQXX@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGVYIGQTGSPGSPSMVR MGYG000002438_03064 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22XE6@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 204833 305918 0 0 0 0 0 0 0 0 0 0 0 0 0 247708 0 0 0 460101 0 0 306583 0 0 0 0 0 0 0 0 0 346323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470322 846196 464887 0 748216 657133 0 464112 0 0 0 585576 425539 0 332950 0 293893 0 493530 527945 949024 441783 0 355369 232202 272501 358777 0 501966 782117 673536 766417 344394 0 0 0 488996 429493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341333 0 0 0 0 0 0 0 0 361651 0 0 0 0 889492 1621699 754522 0 1947559 1127704 0 848667 862281 0 0 1633478 1127440 0 460236 0 1227285 0 1047663 1048590 5098555 653907 0 1268981 1000780 1001439 975145 0 861320 5656599 1175195 3257185 697252 890719 0 0 1393081 939877 -AAGYDFS(Ser->Gly)GDK MGYG000002492_00484 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC transporter, solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4742523 0 0 0 0 2463220 0 0 0 0 3640440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGYDKPFK MGYG000002494_02275;MGYG000002534_00118;MGYG000002477_00485;MGYG000002515_03781 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,3X0JI@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 GM 1.0 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose 1.0 hldD 1.0 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008712,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901576,GO:1903509 1.0 5.1.3.20 1.0 ko:K03274 1.0 ko00540,ko01100,map00540,map01100 1.0 M00064 1.0 R05176 1.0 RC01291 1.0 ko00000,ko00001,ko00002,ko01000,ko01005 1.0 - 1.0 - 1.0 iPC815.YPO0058,iYL1228.KPN_03963 1.0 Epimerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADP-glyceromanno-heptose 6-epimerase. ADP-L-glycero-D-manno-heptose 6-epimerase. - ADP-D-glycero-beta-D-manno-heptose = ADP-L-glycero-beta-D-manno-heptose. 1.0 1.0 1.0 1.0 Metabolic pathways;Lipopolysaccharide biosynthesis 1.0 none 1.0 278777 0 0 0 0 204554 0 0 177526 0 0 0 0 0 0 0 0 0 0 0 0 322068 0 478451 0 230462 0 0 0 0 0 0 0 0 0 0 254515 0 606756 0 0 0 0 978685 0 0 543884 0 0 0 0 0 0 0 0 0 0 0 0 1000239 0 810747 0 338154 0 0 0 0 0 0 0 0 0 0 470639 0 279380 0 0 0 0 596702 0 0 366534 0 0 0 0 0 0 0 0 0 0 0 0 561684 0 465123 0 262813 0 0 0 0 0 0 0 0 0 0 273078 0 240681 0 0 0 0 404550 0 0 276604 0 0 0 0 0 0 0 0 0 0 0 0 351215 0 419500 0 237898 0 0 0 0 0 0 0 0 0 0 0 0 428341 0 0 0 0 0 0 0 1239679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427645 0 734346 0 0 0 0 0 0 0 0 0 0 722380 0 -AAGYDNLK MGYG000002993_00071;MGYG000002143_01292;MGYG000000370_02054;MGYG000002720_01579;MGYG000002156_00957 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,2N727@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 1149556 0 0 0 2771059 0 0 0 0 0 0 0 0 0 0 1501706 0 0 0 0 1679203 0 0 0 0 953661 0 0 0 0 1027248 1784239 0 0 0 1074082 0 0 0 0 0 0 306561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 648409 0 0 0 0 372891 0 0 986505 0 0 0 1075242 0 0 0 0 0 0 0 0 0 0 895469 0 0 0 0 1083860 0 0 0 0 981978 0 0 0 0 688815 936078 0 0 0 939538 0 0 0 0 0 0 1689366 0 0 0 0 0 0 0 0 0 0 2414306 0 0 0 0 0 0 0 0 0 2272422 0 0 0 0 2163236 1659909 0 0 0 0 0 0 264858 0 0 0 405523 0 0 0 0 0 0 0 0 0 0 316888 0 0 0 0 204967 0 0 0 0 127302 0 0 0 0 297336 0 0 0 0 247084 -AAGYDNLKGHK MGYG000004831_00839;MGYG000002720_01579 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,2N727@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGYDVELTYSDNETDR MGYG000000212_01149 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3Y2A7@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10546 1.0 ko02010,map02010 1.0 M00216 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.5 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1152686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGYELGK MGYG000002515_00276;MGYG000002506_02347;MGYG000000093_02751;MGYG000002507_03714;MGYG000001464_01969;MGYG000002494_04436;MGYG000000235_01674 domain d__Bacteria 1.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,3XNNK@561|Escherichia 0.8571428571428571 1236|Gammaproteobacteria 0.8571428571428571 F 0.8571428571428571 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 0.8571428571428571 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 iPC815.YPO3376 0.8571428571428571 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 759660 968842 621487 1024352 749907 3509305 1581069 1188172 1187759 1346183 641609 915082 734935 1500735 1441926 735266 929730 0 1069798 1360125 1607950 4179837 0 4828844 1272009 1016468 1382134 0 1244145 1497973 776828 726941 1353879 1561332 1340730 1117942 1328086 1459456 15538179 16857005 20127186 13000344 15111457 28978195 14904906 12165107 16216091 16435398 3875292 10732526 0 15768830 10752708 10089018 20758238 0 21124429 12601651 18673449 28911940 0 24050074 17199055 13055211 10063295 0 23150899 17419687 7704218 8968121 20117736 12706976 12447599 11676049 11661575 17240593 2203241 1901110 2134631 1584408 1783850 4792391 0 2070056 2262293 2528279 1287004 1282892 1553958 1577344 2600854 2067877 2061708 0 2118683 2329392 2441220 4274392 0 4829182 2321813 2102084 2522569 0 1673914 2085827 1477076 1309006 2237664 2446939 1564917 2301642 1575965 2072253 4311949 2542729 3684037 3665312 2489956 4484284 5929771 3883077 3171416 4049400 1885653 3891533 2576953 3968964 2868315 2586365 3360058 0 2749359 4364099 3665850 5415011 0 4360515 3907643 2556674 3720398 0 3901701 3263338 1908605 2487598 3275004 4383338 4705550 5060147 2686960 3238514 360340 563868 698107 153754 586592 446839 831373 632618 518288 677402 292064 530556 774685 809794 821119 330196 932881 0 1079345 583782 844926 400096 0 349096 507147 510597 347496 0 324239 394982 542572 410920 941374 675161 503502 846027 643019 542936 -AAGYELGKDITLA MGYG000002515_00276;MGYG000002494_04436 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,3XNNK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 iPC815.YPO3376 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 511799 0 0 0 0 0 0 0 0 0 0 0 372118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4501481 0 0 0 0 0 0 0 0 0 0 0 7757786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1080601 0 0 0 0 0 0 0 0 0 0 0 828861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1626555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGYELGKDITLAM(Oxidation)DC(Carbamidomethyl)AASEFYKDGK MGYG000002506_02347;MGYG000002494_04436 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,3XNNK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 iPC815.YPO3376 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 358218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262622 0 558167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1734750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3491792 0 1571522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1665205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGYFNPFLEPMME(Glu->Lys) MGYG000000099_02239 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,267NE@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1782176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGYLWNPLTGVYLFPR MGYG000002478_01405 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKS4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4212405 2305470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1511257 0 0 0 0 0 0 1249242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5034425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAGYTNIEFHK MGYG000002494_04286;MGYG000002535_00504;MGYG000002534_04100;MGYG000003372_04662;MGYG000002506_02507;MGYG000002477_01454 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,3ZJFX@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 EH 1.0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 1.0 serA 1.0 GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iYL1228.KPN_03348 1.0 2-Hacid_dh,2-Hacid_dh_C,ACT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 304150 220847 406956 0 176026 498300 186886 0 217309 311424 0 166682 175471 276856 172508 182714 188659 0 320472 78208 100572 640860 0 701886 297466 142432 0 0 155076 133566 174010 165316 408985 374980 179335 254546 152694 238417 2938395 6009725 6165886 0 5048526 8447694 3447567 0 2306021 3476204 0 2452277 3648262 2934673 1980619 5418647 6232207 0 4184281 2066912 6566749 11603041 0 7936122 4477180 2155955 0 0 6602100 5360444 2512454 2548187 6287690 1881728 1719616 2631670 1966800 5724294 188020 205284 150252 0 162808 559027 95934 0 150403 177523 0 0 0 125634 219773 0 257861 0 0 161139 154726 491860 0 592305 76577 193566 0 0 0 103296 57631 73432 175146 75591 125192 103522 134128 130769 1138121 294506 693290 0 491567 796380 1372097 0 718079 676024 0 386984 435645 839446 782793 683041 685557 0 599301 955587 1401375 976053 0 771783 1178513 852643 0 0 507957 798341 472607 275509 680175 1352472 1495348 1554239 607244 600133 69600 58785 53626 0 71212 169772 0 0 194887 179410 0 85981 0 0 233638 0 172186 0 0 180229 0 156686 0 63866 0 0 0 0 0 0 86390 0 0 366157 0 0 70836 200508 -AAGYTSEPHAAVAYR MGYG000002494_02907 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0083@1|root,COG0498@1|root,KOG1537@2759|Eukaryota,KOG2616@2759|Eukaryota,38DB9@33154|Opisthokonta,3BI93@33208|Metazoa,3D0F1@33213|Bilateria,420W7@6656|Arthropoda,3SQID@50557|Insecta 1.0 33208|Metazoa 1.0 E 1.0 Threonine synthase N terminus 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94809 0 0 0 0 0 0 0 0 0 0 0 0 209545 0 1054643 1372825 1261067 0 1277582 2120830 0 0 0 0 0 0 0 1354882 0 0 1511219 0 1162044 671029 1625646 2371140 0 1929778 1215085 763497 0 0 1528236 1012562 0 0 1283055 0 0 0 681229 1401742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAHAD(Methyl[D](Asp->Glu)TLAAK MGYG000000205_02694;MGYG000000233_02509 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,2PR0E@265975|Oribacterium 1.0 186801|Clostridia 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 778880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 540631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAHADTLAAK MGYG000000205_02694;MGYG000000233_02509 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,2PR0E@265975|Oribacterium 1.0 186801|Clostridia 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 252470 267577 123160 312029 240883 0 236575 178901 314333 262154 387231 244018 0 0 0 261042 349374 0 0 0 0 0 0 0 384200 238055 494752 0 0 0 0 366477 210403 325630 232153 244037 135690 218574 1163842 1218966 828334 1194157 1253762 0 1435798 1229965 841741 1239856 1195489 1474621 0 0 0 1214550 1376420 0 0 0 0 0 0 0 1059571 1130356 1363434 0 0 0 0 1371916 577023 1194461 840189 893454 829315 901763 0 0 0 63105 29231 0 0 34461 61601 69611 0 0 0 0 0 56383 55191 0 0 0 0 0 0 0 96746 56817 91357 0 0 0 0 0 0 105596 51411 65133 51653 0 163965 126513 52079 194453 149057 0 67700 36608 122081 0 82544 125163 0 0 0 157111 118567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 61858 36079 92934 113294 83950 87394 43744 126519 286233 177365 141463 234496 0 272149 170652 134934 250802 228079 175616 0 0 0 164795 55463 0 0 0 0 0 0 0 147847 70336 157866 0 0 0 0 128378 267935 175801 110098 83764 111018 142976 -AAHAETLAAK MGYG000000255_02201 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,2PR0E@265975|Oribacterium 1.0 186801|Clostridia 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 643968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAHAQDMVTGFIR MGYG000004735_00145 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2651835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 846877 0 0 0 0 0 0 -AAHDAIKIHC(Carbamidomethyl)K MGYG000000243_02576 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAHEAIKVHC(Carbamidomethyl)K MGYG000004797_03519;MGYG000002478_00894 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 639733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98034 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAHFGNNVSHSHR MGYG000000184_00823;MGYG000001338_01758 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL28 family 1.0 rpmB 1.0 - 1.0 - 1.0 ko:K02902 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 201539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283862 686633 37966 0 0 0 0 51365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2074437 123318 0 0 0 0 0 0 0 0 85070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342585 513063 159242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54209 0 0 0 0 0 0 0 0 385252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1253552 721594 787132 0 0 0 0 166384 -AAHFGNNVSHSHRR MGYG000000184_00823;MGYG000001338_01758 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL28 family 1.0 rpmB 1.0 - 1.0 - 1.0 ko:K02902 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 955365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAHFITLVPK MGYG000002478_04295 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1359@1|root,COG1359@2|Bacteria,4NUHJ@976|Bacteroidetes,2FT37@200643|Bacteroidia,4ARA5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Antibiotic biosynthesis monooxygenase 1.0 ycnE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ABM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 776108 0 0 0 0 0 0 0 0 0 0 1137521 0 540705 0 0 0 0 886257 0 0 0 0 669453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789387 0 0 0 0 0 0 0 0 0 0 1156274 0 52949 0 0 0 0 604904 0 0 0 0 503887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312457 0 0 0 0 0 0 0 0 0 0 488083 0 427159 0 0 0 0 408887 0 0 0 0 330131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 695175 0 0 0 0 0 0 0 0 0 0 493374 0 1175672 0 0 0 0 924198 0 0 0 0 758476 0 0 0 0 0 0 0 0 0 0 -AAHFVTLVPK MGYG000000243_01283 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1359@1|root,COG1359@2|Bacteria,4NUHJ@976|Bacteroidetes,2FT37@200643|Bacteroidia,4ARA5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Antibiotic biosynthesis monooxygenase 1.0 ycnE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ABM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 745949 0 0 0 0 0 0 0 0 0 0 455574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 889415 0 0 0 0 827603 0 0 423621 0 0 0 0 0 0 0 0 0 0 416797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308774 0 0 0 0 428659 0 0 389825 0 0 0 0 0 0 0 0 0 0 333753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262288 0 0 0 0 359364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAHLPEQM(Oxidation)IQNIAK MGYG000002281_00012;MGYG000001346_00649;MGYG000000013_03147;MGYG000004876_02408;MGYG000004019_01939;MGYG000001661_02572;MGYG000002549_00046;MGYG000001378_03196;MGYG000001313_02981;MGYG000003252_02162;MGYG000002455_03779;MGYG000001345_01370;MGYG000000196_04091;MGYG000003681_02139;MGYG000000029_01191 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 454980 0 0 558723 224546 0 0 245580 0 401525 545121 0 0 0 1097364 1082540 453451 0 0 0 706380 384024 252297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333106 0 0 187852 229005 0 0 1184443 0 722635 474481 0 0 0 292201 292036 331139 0 0 0 220768 0 193405 0 0 0 271478 0 0 0 0 0 0 0 0 0 0 0 761741 0 0 720756 791518 0 0 713405 0 1078595 514423 0 0 0 611635 784703 1038655 0 0 0 458240 827078 808805 0 0 0 667597 0 0 0 0 0 0 0 0 0 0 0 448202 0 0 367300 599317 0 0 320042 0 460058 244358 0 0 0 708092 463482 355059 0 0 0 367081 488129 392647 0 0 0 460702 0 0 0 0 0 0 0 0 0 0 0 303919 0 0 557226 577092 0 0 303140 0 1024455 137674 0 0 0 313542 233390 327152 0 0 0 534402 290462 369012 0 0 0 229278 0 0 0 0 0 0 0 0 0 0 -AAHLPEQMIQNIAK MGYG000002281_00012;MGYG000001346_00649;MGYG000000013_03147;MGYG000004876_02408;MGYG000004019_01939;MGYG000001661_02572;MGYG000002549_00046;MGYG000001378_03196;MGYG000001313_02981;MGYG000003252_02162;MGYG000002455_03779;MGYG000001345_01370;MGYG000000196_04091;MGYG000003681_02139;MGYG000000029_01191 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 4489921 5288466 3665177 5387890 3764832 3710884 7794139 4502736 5240299 4368123 10218183 4910571 3548056 1666515 3955008 4241313 4526733 1020270 1280491 3558348 3892002 3389563 2724850 5960550 3675756 4400502 4509279 1784086 4499975 4542666 0 5239079 0 5538060 3638490 4532824 1797288 3409131 7479260 3951304 7332182 8098628 6361962 8809529 7451574 9812649 7650966 11288926 14804582 9204102 6863619 10231100 9441213 10559906 7843109 2299224 7515448 7567636 7382216 10066556 3084094 6843285 8084933 9617064 8822803 2315274 6948548 6986512 5692588 8358904 7577040 7651246 8205374 7867523 8709343 7939885 3626177 3390211 6302466 3640947 5897309 5383004 6004721 3948342 5903916 3228646 9633084 5242997 3131762 4518705 2804137 4819852 4245204 7653048 3113110 3794824 4230267 3705013 5798756 5486072 3213852 3528283 3278140 6114637 5012945 4346962 4905064 3442781 4115077 3523653 3550028 5827956 3993819 5227325 4004730 2744599 3450520 2872227 3874755 3699297 4370611 4111021 3497054 3295940 5980604 4555999 4798376 3923617 3988025 4653633 3293134 3020288 3530592 3331603 5336996 2617078 3997126 1895746 4463651 4905048 4308231 1035357 2706340 3862099 3035184 4522679 3759724 4554615 4637223 5750978 4861538 2675726 4008857 3406812 3241150 4065526 5150093 6336608 4541029 4244000 4502905 3404954 11721701 3714461 5523007 2624398 3847800 5005676 4049539 4778879 3045580 5449378 2902402 4805387 3509695 5259934 3855793 4247456 3178078 4468820 3590157 5796141 3801106 3522922 2349755 4501073 3690214 3562798 4517327 4031972 -AAHPNWDLTFK MGYG000001319_02248 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia,4BYAS@830|Butyrivibrio 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1128904 0 0 0 0 825458 0 0 0 0 1442119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1953248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858678 0 0 0 0 545365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3731432 0 0 0 0 2213869 0 0 0 0 0 0 0 0 0 0 -AAHSFNLLDAR MGYG000002477_00434;MGYG000002534_00166;MGYG000003372_03454;MGYG000002535_04458;MGYG000002494_02222;MGYG000002515_03452;MGYG000002506_03203 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,3X0QV@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 glycyl-tRNA synthetase alpha subunit 1.0 glyQ 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 6.1.1.14 1.0 ko:K01878 1.0 ko00970,map00970 1.0 M00360 1.0 R03654 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iAF1260.b3560,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 1.0 tRNA-synt_2e 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine--tRNA ligase. glycyl-tRNA synthetase. - ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 108279 0 0 111352 0 0 0 97013 0 0 0 0 0 0 0 0 0 0 73942 229665 0 132084 34804 0 0 0 126313 116208 0 0 0 0 0 0 0 0 0 0 672205 0 606802 888333 0 0 0 891740 0 0 0 611893 0 0 765485 0 700670 0 866547 1062279 0 853362 801257 0 0 0 899082 740896 0 0 753252 0 0 0 0 569851 0 0 132170 0 246536 502493 0 0 0 246944 0 0 0 199106 0 0 216929 0 52835 0 237383 512623 0 514676 226307 0 0 0 106464 157077 0 0 174913 0 0 0 0 165545 0 0 79207 0 155520 76685 0 0 0 63172 0 0 0 65556 0 0 93279 0 105449 0 125803 86330 0 71706 0 0 0 0 82775 138774 0 0 141029 0 0 0 0 205457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAHSVANAVSK MGYG000004769_00967 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,4H2B2@909932|Negativicutes 1.0 909932|Negativicutes 1.0 S 1.0 TRAP transporter solute receptor TAXI family 1.0 - 1.0 - 1.0 - 1.0 ko:K07080 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 NMT1_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 36310 150499 0 222694 177188 0 222420 0 0 454724 88740 0 0 0 0 0 0 136380 194651 0 63278 0 372019 0 0 0 0 0 0 0 0 251288 0 247056 0 0 143720 0 1259777 1370884 0 2193505 2173092 0 1796281 0 0 2289529 1487351 0 0 0 0 0 0 1464929 929648 0 1895930 0 1485858 0 0 0 0 0 0 0 0 1213448 0 798808 0 0 774615 0 855660 642347 0 429584 605680 0 717800 0 0 675002 165673 0 0 0 0 0 0 643858 779863 0 830387 0 642747 0 0 0 0 0 0 0 0 574742 0 619380 0 0 564419 0 142713 104832 0 85655 146114 0 127264 0 0 259616 94673 0 0 0 0 0 0 321305 93920 0 220233 0 178132 0 0 0 0 0 0 0 0 383792 0 116070 0 0 160003 0 69539 58845 0 0 27235 0 40839 0 0 0 35389 0 0 0 0 0 0 67855 85763 0 38735 0 0 0 0 0 0 0 0 0 0 103187 0 128914 0 0 83081 -AAI(Xle->Val)DNSYNVLR MGYG000002935_00389;MGYG000000243_01847;MGYG000002478_01470 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1571373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAI(Xle->Val)GIPEEELR MGYG000000196_04526;MGYG000000029_01860;MGYG000001345_00467;MGYG000003367_00149;MGYG000000044_01913;MGYG000002033_00099;MGYG000002478_01776;MGYG000002905_01187;MGYG000000243_02506;MGYG000001306_00718;MGYG000003221_00520;MGYG000002455_03337;MGYG000000174_01424;MGYG000000355_00809;MGYG000004797_01374;MGYG000000273_02673;MGYG000002575_01735 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.5294117647058824 976|Bacteroidetes 1.0 G 0.6470588235294118 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.5294117647058824 fba 0.6470588235294118 - 1.0 4.1.2.13 0.6470588235294118 ko:K01624 0.6470588235294118 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6470588235294118 M00001,M00003,M00165,M00167,M00344,M00345 0.6470588235294118 R01068,R01070,R01829,R02568 0.6470588235294118 RC00438,RC00439,RC00603,RC00604 0.6470588235294118 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6470588235294118 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6470588235294118 0.6470588235294118 0.6470588235294118 0.6470588235294118 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.6470588235294118 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5406843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAI(Xle->Val)YSGEK MGYG000001780_00304;MGYG000004876_01447;MGYG000002478_02197 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2209580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIAAAC(Carbamidomethyl)QTK(Lys->Arg) MGYG000003921_00859 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3WGMD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7433983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIAAAEGDYK MGYG000004658_01702;MGYG000000074_00133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 801646 608804 383570 780187 727167 0 857841 0 549083 171498 466344 571245 219052 365564 360958 0 594455 0 0 675858 865588 0 0 415820 346107 510354 656933 0 544020 637160 276887 586219 189628 180045 451514 720129 497138 264010 2529798 1562036 2406682 0 2095531 1382622 1404001 0 2714231 2606687 1418615 0 1258559 2763659 2761833 2217658 2300091 0 2832516 3699713 2579151 1891920 0 1541365 1794772 2727983 0 0 0 2010571 1913231 2040495 0 2712974 2789001 2524268 0 2208945 447989 212011 603268 328203 507256 0 439640 372244 514652 484353 364094 252611 0 452293 355492 0 311490 0 3857680 223977 422210 0 0 0 281558 0 439258 0 267160 520843 414419 0 0 0 445571 526366 404809 0 1521087 1109344 1657418 1295773 1161341 1181215 1850183 1309176 1549297 1291816 1243700 1712396 1478906 1314501 1754779 928096 1163540 0 1850877 1530962 2012607 690718 0 817894 1959667 2265270 1193725 0 1440048 1546736 1064374 1767787 1684068 0 1345309 2294184 1754061 872761 13291255 11090158 12082389 24238075 18544207 18322139 15888811 10785072 16952914 12110487 10544233 17599658 15868490 9086203 12403568 14563658 21586052 0 15603425 27395047 11243435 11378715 0 14134481 13444073 28495704 11848963 0 11233509 25864877 11907800 11915708 8096152 744408 14716813 29270637 18955390 12750384 -AAIAAAQANPNAK MGYG000002506_03879;MGYG000003360_01349;MGYG000002515_04072;MGYG000000107_04045;MGYG000002534_04395;MGYG000002494_02689;MGYG000002535_03828;MGYG000002323_03811 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily 1.0 frdA 1.0 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.0 1.3.5.4 1.0 ko:K00244 1.0 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 1.0 M00009,M00011,M00150,M00173 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECIAI39_1322.ECIAI39_4621,iEcSMS35_1347.EcSMS35_4625,iPC815.YPO0360 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 1245469 811598 522790 865862 0 720295 1312164 1191801 697200 927451 320611 736950 260484 907222 187552 213405 598950 0 1215767 395195 861590 1185402 0 1202788 521355 1294518 920859 0 1067872 963957 0 722806 436194 680400 1129903 932852 820560 584674 3052606 3496507 3064766 3035657 0 5607835 3166342 0 2050416 4269336 4112162 2650013 1539483 2734195 2464229 1814731 3659885 0 3412436 0 3423091 5840175 0 4444776 3054219 2604074 3112022 0 4199355 3046077 0 3376840 3436990 3564527 3002279 2782096 2557796 2468011 1175261 1882105 1245701 1292628 0 2834219 2344974 2028056 1257160 2591491 3004635 2064933 1746817 1508088 1518387 2218303 2366106 0 1774624 1604022 1970289 1930374 0 1435147 1998394 1092084 1279674 0 2025796 1974162 0 1075099 1880145 1541518 1823703 1645580 1052256 900860 171697 1421939 1532739 438232 0 1330127 0 325351 906987 1718173 1660752 1639526 1413601 506393 1216571 1142606 1016233 0 1021281 542626 312641 293268 0 800669 253311 119458 1218581 0 2209530 1231615 0 2200224 1151723 821911 961495 1222508 636790 900311 0 287304 163518 163001 0 137188 1061927 185417 0 0 2050604 170615 160831 190263 243160 107179 0 0 0 0 0 0 0 194358 109216 0 0 0 0 0 0 173837 351573 203364 141810 0 0 0 -AAIAADK MGYG000002438_01767;MGYG000001489_01457 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG3063@1|root,COG3063@2|Bacteria,4PKG6@976|Bacteroidetes,2G3G2@200643|Bacteroidia,2322F@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 NU 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 878160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIAADKAMAK MGYG000000138_03130;MGYG000000044_02742 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG3063@1|root,COG3063@2|Bacteria,4PKG6@976|Bacteroidetes,2G3G2@200643|Bacteroidia,2322F@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 NU 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 474551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 538438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIAADKFQR MGYG000002218_00670 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides sp000436495|m__MGYG000002218 1.0 COG3063@1|root,COG3063@2|Bacteria,4PKG6@976|Bacteroidetes,2G3G2@200643|Bacteroidia,2322F@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 NU 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2078349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 414432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIAAEGTPAEYK MGYG000004479_01116;MGYG000000042_02678;MGYG000000781_02114;MGYG000001835_01025;MGYG000004763_00186 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 0.8 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 500155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 946896 0 0 0 0 1653584 0 0 896439 0 0 0 0 1088054 3857523 0 0 0 0 5308798 0 0 0 0 4823404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 615363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2718469 0 0 0 0 2066235 0 0 0 0 1844579 0 0 0 0 0 0 0 0 0 0 -AAIAAGADGLMIEVHPC(Carbamidomethyl)PAK MGYG000000179_03817 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,21YS6@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 8.87 1.0 aroF 1.0 - 1.0 2.5.1.54 1.0 ko:K03856 1.0 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 1.0 M00022 1.0 R01826 1.0 RC00435 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAHP_synth_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-deoxy-7-phosphoheptulonate synthase. phospho-2-oxo-3-deoxyheptonate aldolase. Formerly EC 4.1.2.15. D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2- dehydro-3-deoxy-D-arabino-heptonate + phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of amino acids;Metabolic pathways;Biosynthesis of secondary metabolites;Phenylalanine, tyrosine and tryptophan biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683493 0 0 0 0 0 0 0 0 0 -AAIAAGAPK MGYG000002506_00529;MGYG000001692_01757 order d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.5 1236|Gammaproteobacteria 0.5 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.5 adhE 0.5 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 0.5 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 0.5 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 455007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766224 0 597662 0 0 0 0 0 0 0 0 0 0 0 0 0 149299 0 0 1061274 0 0 1035427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460834 0 288100 0 0 0 0 0 0 0 0 964975 0 0 667322 0 711575 0 0 1033755 0 0 3101189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2090251 0 2930755 0 0 0 0 0 0 0 0 1131990 0 0 791570 0 990111 0 0 3289709 0 0 2414850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5180097 0 5170649 0 0 0 0 0 0 0 0 2319453 0 0 1658184 0 3424125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIADGNEDAK MGYG000000212_00407 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 631242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 967540 0 438947 0 0 0 0 1385528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421193 0 0 0 0 0 0 0 0 0 0 632145 0 0 0 0 493262 0 581003 0 0 0 0 768863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 567497 0 0 0 0 0 0 0 0 0 0 803512 0 0 0 0 576064 0 403415 0 0 0 0 3077100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIADLEKAEDSAK MGYG000002492_01714 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3XZ0G@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate 1.0 argJ 1.0 - 1.0 2.3.1.1,2.3.1.35 1.0 ko:K00620 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028 1.0 R00259,R02282 1.0 RC00004,RC00064 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ArgJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 amino-acid N-acetyltransferase. | glutamate N-acetyltransferase. N-acetylglutamate synthase. | ornithine transacetylase. Also acts with L-aspartate and, more slowly, with some other amino acids. | Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity. acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate. | L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L- glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 179451 0 101899 0 0 0 314925 0 0 201759 0 0 388058 0 0 80039 70266 229309 186606 0 0 0 152529 0 252870 172635 0 159733 0 88071 233437 0 0 0 305912 0 195337 0 369623 0 1274220 582742 1270107 324633 580855 392050 0 0 1008236 413858 318011 337476 0 308132 0 3271417 0 0 0 288614 1406886 300632 415450 427586 172985 2423554 0 285993 695382 531018 1133120 241707 375916 458256 271190 1652889 1047232 0 5424798 1122220 1572352 842605 1122715 1124230 908987 1358758 2345986 2224084 2588442 1114785 0 2663556 1195699 841138 1205047 0 0 1004478 1193532 765976 1431837 1373377 1481794 1333481 0 1208422 1995040 979958 5355157 1519783 1501048 908243 1277151 4693854 314011 0 0 0 0 0 0 0 337195 134544 234190 0 164019 84733 0 284223 228057 0 0 0 0 0 0 130230 0 310080 0 0 0 324561 459022 152768 389886 101702 334997 0 0 437498 0 0 0 0 320484 0 0 228605 0 0 0 0 85065 0 0 0 0 0 0 0 0 0 0 0 182457 0 0 0 0 90967 0 536729 0 214964 0 0 0 0 -AAIADLTEAGVR MGYG000001365_01213;MGYG000000591_01067 genus d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A 1.0 COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,4H40Q@909932|Negativicutes 1.0 909932|Negativicutes 1.0 E 1.0 methylmalonyl-CoA epimerase 1.0 mce 1.0 - 1.0 5.1.99.1 1.0 ko:K05606 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R02765,R09979 1.0 RC00780,RC02739 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glyoxalase_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA epimerase. methylmalonyl coenzyme A racemase. - (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 435080 161981 0 249627 467093 540335 585050 0 0 0 0 0 0 0 0 0 834644 482973 0 0 0 443883 0 361193 0 473401 0 0 133760 0 414300 369376 255705 0 0 216969 0 0 0 314784 0 0 0 0 242340 0 0 0 0 0 0 0 292928 919016 0 0 0 0 0 0 0 0 0 920269 0 0 169003 0 0 0 0 0 0 309232 0 0 0 0 310168 435718 312098 490120 315587 222583 272773 453568 0 0 0 226810 327131 0 0 286935 0 0 1496659 286151 0 408104 0 542020 283094 0 360814 504543 0 321452 0 0 0 120497 0 0 387662 0 261415 392434 0 0 0 0 377802 447078 400895 0 634780 0 461334 850839 634862 0 0 0 962372 362588 0 0 0 895828 0 658054 515322 467685 607904 624812 0 0 0 453532 0 0 12421604 16382784 11970696 17210469 9044165 15640280 10954789 7331293 11696448 8687790 10916706 0 8708825 6393202 9176087 16914920 10303878 10934822 0 16509062 16168373 21511736 0 9011970 0 17133582 10703284 10839331 13956232 17151740 9858486 11960347 15489365 0 10505689 14634083 -AAIADYK MGYG000002506_02049;MGYG000002525_00332;MGYG000002323_03053 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,3XPIY@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters 1.0 iscU 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 1.0 - 1.0 ko:K04488 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_3996,iB21_1397.B21_02385,iBWG_1329.BWG_2293,iE2348C_1286.E2348C_2812,iEC042_1314.EC042_2733,iEC55989_1330.EC55989_2814,iECABU_c1320.ECABU_c28350,iECBD_1354.ECBD_1155,iECB_1328.ECB_02421,iECDH10B_1368.ECDH10B_2696,iECDH1ME8569_1439.ECDH1ME8569_2456,iECD_1391.ECD_02421,iECED1_1282.ECED1_2960,iECH74115_1262.ECH74115_3761,iECIAI1_1343.ECIAI1_2581,iECIAI39_1322.ECIAI39_2730,iECNA114_1301.ECNA114_2608,iECO103_1326.ECO103_3046,iECO111_1330.ECO111_3253,iECO26_1355.ECO26_3576,iECOK1_1307.ECOK1_2878,iECP_1309.ECP_2534,iECS88_1305.ECS88_2705,iECSE_1348.ECSE_2815,iECSF_1327.ECSF_2373,iECSP_1301.ECSP_3473,iECUMN_1333.ECUMN_2849,iECW_1372.ECW_m2755,iECs_1301.ECs3395,iEKO11_1354.EKO11_1204,iETEC_1333.ETEC_2686,iEcDH1_1363.EcDH1_1139,iEcE24377_1341.EcE24377A_2814,iEcHS_1320.EcHS_A2680,iEcSMS35_1347.EcSMS35_2682,iEcolC_1368.EcolC_1148,iG2583_1286.G2583_3059,iJO1366.b2529,iSDY_1059.SDY_2725,iSFV_1184.SFV_2577,iSF_1195.SF2576,iSFxv_1172.SFxv_2832,iSSON_1240.SSON_2611,iS_1188.S2748,iUMN146_1321.UM146_04055,iUMNK88_1353.UMNK88_3182,iUTI89_1310.UTI89_C2851,iWFL_1372.ECW_m2755,iY75_1357.Y75_RS13200,iZ_1308.Z3796,ic_1306.c3055 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 669788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618130 0 724556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1140601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1143121 0 910153 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2321462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1555597 0 2344587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1375720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 512997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIAEDPDYAK MGYG000000164_01266 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0579@1|root,COG2906@1|root,COG0579@2|Bacteria,COG2906@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,25V7H@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 BON,DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 1327455 0 0 0 0 0 1754803 1728721 0 2018262 0 0 0 0 1782738 0 0 0 1122642 0 0 0 0 0 1680170 1330369 0 0 0 0 0 0 0 0 0 1150085 1574999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407421 0 0 0 0 0 0 0 0 301167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477552 0 0 0 0 0 0 0 0 609513 0 0 0 0 0 0 646506 0 0 0 0 0 0 0 0 0 337387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156483 0 0 0 0 0 0 1431842 0 0 0 0 0 0 0 0 0 2051862 0 0 -AAIANAR MGYG000003683_00464;MGYG000000756_00775 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 188259 0 0 0 0 0 0 0 0 0 364370 0 0 0 0 71347 0 148818 0 0 62982 0 85271 0 0 66493 0 0 470137 0 0 0 0 0 0 881380 0 0 279143 0 0 0 0 0 0 0 0 0 2358793 0 0 609973 0 1502830 0 295280 0 0 1243113 0 296284 0 0 2239531 0 0 2063069 0 301392 0 0 0 0 585305 0 0 226260 0 0 0 0 0 0 0 0 0 236663 0 0 346015 0 0 0 306116 0 0 159149 0 354551 0 0 350666 0 0 180393 0 832597 0 0 0 0 362068 0 0 52062 0 0 0 0 0 0 0 0 0 162483 0 0 0 0 184017 0 0 0 0 91052 0 43776 0 0 0 0 0 64572 0 62046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60371 0 68667 0 0 81176 0 0 0 0 102152 0 0 0 0 0 0 0 0 0 70006 -AAIAQIEKPNAE MGYG000000164_02291 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3Y0GK@572511|Blautia 1.0 186801|Clostridia 1.0 U 1.0 COG COG1862 Preprotein translocase subunit YajC 1.0 yajC 1.0 - 1.0 - 1.0 ko:K03210 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2 1.0 - 1.0 - 1.0 Ftsk_gamma,YajC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 1219157 0 1362205 0 0 0 0 0 1799189 0 0 0 1036096 0 1692596 0 0 0 0 0 0 0 0 0 0 0 0 971930 1289864 0 0 0 0 0 0 0 0 0 256336 0 357537 0 0 0 0 0 186758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282796 375646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIAQVEK MGYG000002992_02024;MGYG000000198_04879;MGYG000001496_02754;MGYG000002279_02611;MGYG000001789_02120 domain d__Bacteria 1.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,27VNQ@189330|Dorea 0.4 186801|Clostridia 0.8 U 0.8 Preprotein translocase subunit 0.8 yajC 0.8 - 1.0 - 0.8 ko:K03210 0.8 ko02024,ko03060,ko03070,map02024,map03060,map03070 0.8 M00335 0.8 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 0.8 3.A.5.1,3.A.5.2 0.8 - 1.0 - 1.0 Ftsk_gamma,YajC 0.8 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8 0.8 0.8 0.8 Protein export;Quorum sensing;Bacterial secretion system 0.8 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2253157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIAVLPATYK MGYG000000243_01881 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3637@1|root,COG3637@2|Bacteria,4NIPZ@976|Bacteroidetes,2FQ2F@200643|Bacteroidia,4ANBF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 COG NOG32048 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2095035 3722034 1842047 2747515 3056136 2503295 2616956 2681354 1972431 2091263 3186122 0 3644691 1910109 1835209 3406017 3181069 0 0 1781265 2368382 1956976 0 3087515 1963890 2546153 2945481 0 0 2519982 3345949 2539637 2462244 2783975 2387249 2428173 2259515 1689178 492384 255058 387132 608476 371423 253427 441960 550649 556308 572459 513877 0 624871 472947 527621 543218 452491 0 0 411597 0 556311 0 530732 279833 0 355032 0 0 370731 316230 368538 359051 321128 400625 309096 402915 435780 498670 865436 267223 332160 678459 460171 422791 180762 246937 270831 230476 0 141938 261509 233094 317044 313062 0 0 0 142953 207942 0 710287 0 300638 308213 0 0 188047 841844 461436 301919 269121 280524 419367 314061 391270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIAYGADEVDVVFPYR MGYG000002494_02883;MGYG000002506_04111;MGYG000002515_04338;MGYG000003390_03926;MGYG000002507_00239;MGYG000000107_03772;MGYG000003365.1_03302 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3ZJCJ@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 F 1.0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 deoA 1.0 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 1.0 2.4.2.4 1.0 ko:K00758 1.0 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 1.0 - 1.0 R01570,R02484,R08222,R08230 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 1.0 Glycos_trans_3N,Glycos_transf_3,PYNP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thymidine phosphorylase. pyrimidine phosphorylase. In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.-!-Formerly EC 2.4.2.23. phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine. 1.0 1.0 1.0 1.0 Metabolic pathways;Drug metabolism - other enzymes;Bladder cancer;Pyrimidine metabolism 1.0 none 1.0 859828 488261 748279 953961 715617 602100 1118030 1299120 809222 1496784 388232 580670 243314 781367 564036 374875 1002071 0 833740 879051 755416 622201 0 817466 681483 1046367 781400 0 914283 1080829 949231 922283 145131 901546 874643 744737 791903 635743 1036196 1045102 846347 1079680 1357755 1626681 1260302 1288197 1154742 1712054 864402 1285394 737757 1171558 1280624 971376 1684492 0 1331711 950052 1262129 1876057 0 1537903 1353531 1066437 1472985 0 1708423 1004708 733496 1398403 1028652 929633 985320 766733 863498 596484 1119166 1038706 204748 6245 1562093 1228904 1387094 1487554 2686283 1399610 919537 1055119 1087987 1238026 1032640 1052366 865891 0 1037117 1002988 817638 852875 0 2804547 1554037 6955045 1245320 0 1242119 868109 1018623 3253916 1137543 1315470 2416316 3739011 3254211 2200037 4666642 2927271 3765450 3947685 5590184 0 5186409 5923748 4994366 6020285 0 4690035 8233532 5338658 5195819 3823293 5406804 0 4847013 4974070 21014718 9306381 0 9340671 8646422 5939189 0 0 9526272 7279294 113533 7181992 8046292 11518071 12649254 6818143 4229925 5341427 0 0 157149 5492 0 238211 0 0 7132 0 0 0 3146851 0 3888 0 0 0 0 17775 206107 48640 0 309399 0 0 0 0 4753 91268 0 0 5321 72900 12595 0 58843 5274 -AAIDAQK MGYG000000233_02449 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,36DUZ@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 Aminotransferase 1.0 - 1.0 - 1.0 - 1.0 ko:K10907 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 ABC_tran,Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 243287 0 0 0 0 0 131604 0 0 283463 0 0 0 330119 0 0 0 0 142384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194748 0 329124 0 0 0 0 0 518497 0 0 899254 0 0 0 305123 0 0 249988 0 660198 0 0 0 0 0 0 218118 0 0 0 0 0 0 0 0 0 0 351155 0 312293 0 0 0 0 0 164217 0 0 121829 0 0 0 89082 0 0 193404 0 84814 0 0 0 0 0 0 233359 0 0 0 0 0 0 0 0 0 0 78784 0 0 0 0 0 0 0 426733 0 0 150718 0 0 0 0 0 0 0 0 223784 0 0 0 0 0 0 53837 0 0 0 0 0 0 0 0 0 0 145717 0 130747 0 0 0 0 0 137069 0 0 0 0 0 0 116438 0 0 81866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIDAYYDQYGVK MGYG000000262_01269 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,25V0N@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133178 0 447863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378482 0 332153 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIDAYYEQYGA(Ala->Val)K MGYG000002992_01058;MGYG000002304_01630;MGYG000002528_00495;MGYG000001338_00074;MGYG000000206_02791;MGYG000001456.1_02603;MGYG000004785_01588;MGYG000000200_01565;MGYG000002445_01039;MGYG000000278_03671;MGYG000002216_02002;MGYG000000184_02212;MGYG000001714_02809;MGYG000002756_01770;MGYG000000028_01453 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 0.4 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 859049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 777310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIDAYYEQYGAK MGYG000002992_01058;MGYG000002304_01630;MGYG000002528_00495;MGYG000001338_00074;MGYG000000206_02791;MGYG000001456.1_02603;MGYG000004785_01588;MGYG000000200_01565;MGYG000002445_01039;MGYG000000278_03671;MGYG000002216_02002;MGYG000000184_02212;MGYG000001714_02809;MGYG000002756_01770;MGYG000000028_01453 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 0.4 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 1159014 1378935 1558836 0 0 907595 626350 1300083 0 0 1625553 1217191 1409584 0 1378734 1173843 888614 968783 721884 1278816 1027546 858088 699678 617334 1177002 888434 856849 933499 943994 1063702 630943 1418897 1128745 1099341 0 634367 516689 1097676 0 3452571 621284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1237081 0 0 0 0 1644619 0 320052 4078620 0 0 0 0 0 0 0 1131897 2390855 988436 0 0 823096 793959 1049829 0 0 624809 1041071 1054881 0 950830 1023009 1013041 735501 857726 1060131 906083 1307618 937474 725261 993121 1075166 1174571 1171825 1080383 1062509 969796 1419472 1076299 1476046 0 831368 1050712 817371 0 2422766 1172067 0 0 0 685876 0 0 0 916022 958577 531310 0 0 1317164 750225 0 0 187287 0 699264 0 474221 0 0 540266 879415 796527 843003 2368098 0 1257696 0 0 0 0 1807457 0 1998878 1537587 0 0 0 1101586 633648 0 0 1094919 865361 1114106 0 0 582420 0 633474 539086 0 1168173 805097 856546 0 0 0 928859 889529 1115795 0 1584586 0 2206467 0 0 0 0 1385188 -AAIDAYYEQYGAKH MGYG000002528_00495;MGYG000000028_01453 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,3WGS1@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 211698 0 0 0 143582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139369 0 183844 0 0 0 0 0 0 0 85492 0 0 0 0 0 0 0 440854 0 0 0 209670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196491 0 369510 0 0 0 0 0 0 0 208138 0 0 0 0 0 0 0 1371135 0 0 0 767101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1538741 0 553082 0 0 0 0 0 0 0 1335497 0 0 0 0 0 0 0 169267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIDAYYEQYGVK MGYG000001086_00030;MGYG000000233_02103;MGYG000000205_02528;MGYG000001199_01180;MGYG000002290_03136 domain d__Bacteria 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 0.6 186801|Clostridia 0.8 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 1043880 233045 0 823909 506087 326521 1334873 1065587 1219945 1125781 0 645764 0 762690 0 0 0 0 927815 985186 0 640831 0 515394 850003 909145 0 0 0 0 0 380851 0 1321165 0 898704 681212 356589 1414315 903821 804549 1777463 1012578 661791 1420742 1481150 1089598 1913338 1202874 1920541 0 1452198 1385429 0 0 0 1212632 1451847 0 820287 0 621872 1345164 1185708 0 0 0 0 0 1056858 896607 1408729 0 1319421 1050681 683212 385328 0 434167 0 0 0 0 580344 559186 562505 0 0 0 0 489395 0 0 0 0 312699 0 0 0 0 721028 589326 0 0 0 0 0 0 0 623284 0 0 441354 0 1135296 544269 732542 827226 864446 896351 1136764 1131440 836569 1184902 842994 584760 0 972141 929952 0 0 0 628296 1136528 0 972388 0 625017 1063592 896324 0 0 0 0 0 864466 773273 1100600 0 1105899 775536 676160 0 0 0 0 0 281507 0 0 293480 314599 442954 0 0 0 0 0 0 0 0 347407 0 0 0 451018 0 0 0 0 0 0 0 0 177165 0 0 0 238019 266482 -AAIDDYYK MGYG000002517_00833 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 319840 0 0 0 0 0 0 0 0 0 0 0 0 253651 0 0 0 0 0 0 0 0 0 0 0 289571 480988 0 0 0 0 0 0 0 0 289474 424731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89648 0 0 0 0 0 0 0 0 0 0 0 171213 0 0 0 0 0 0 0 0 0 109018 0 0 177269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216715 0 0 0 0 0 0 0 0 0 0 0 1607714 0 0 0 0 0 0 0 0 0 0 0 0 2170086 0 0 0 0 0 0 0 0 0 0 0 1983454 1717864 0 0 0 0 0 0 0 0 1791527 2271985 0 1376396 0 0 0 0 0 0 0 0 0 0 0 0 1876084 0 0 0 0 0 0 0 0 0 0 0 1661157 2040770 0 0 0 0 0 0 0 0 2405491 1629237 0 -AAIDDYYR MGYG000000133_02579 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 222387 118396 316939 0 0 140206 233259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221998 0 123824 0 0 299662 0 0 0 445158 0 0 0 187339 350719 0 0 109080 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140224 0 0 0 0 0 0 0 0 0 0 0 0 2090655 1894354 1729844 0 0 1101280 2852877 0 0 0 1672024 0 0 3916767 1924995 0 0 0 0 0 2614548 1609532 0 1231923 0 1700592 2331075 0 2827894 0 0 0 2941077 1922849 1363932 0 1476245 1311574 -AAIDEYYK MGYG000002492_02249 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252316 0 0 0 0 184305 0 0 0 0 120518 0 0 0 0 200866 0 0 0 0 0 0 0 276999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1401455 0 0 0 0 907778 0 0 0 0 1458084 0 0 0 0 340866 0 0 0 0 481840 0 0 1128431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633598 0 0 0 0 1069192 0 0 0 0 1132314 0 0 0 0 1540085 0 0 0 0 1328428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 173280 0 0 0 0 206943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184673 0 0 0 0 119752 0 0 0 0 391393 0 0 0 0 0 0 0 0 0 0 -AAIDHNIPLITNAR MGYG000001489_01217;MGYG000002438_01117;MGYG000003521_01059 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia,22X6E@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 EF 1.0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398174 0 0 0 0 156784 0 0 0 0 315585 0 510891 0 0 0 0 0 0 0 0 -AAIDLEKDSAELKAELENATGQK MGYG000002492_00340 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2007604 0 0 0 0 0 0 0 0 0 1052733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376731 0 0 0 0 0 0 0 0 0 612608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1196610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIDLFGIADK MGYG000002506_02523 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0126@1|root,KOG1367@2759|Eukaryota,37R6T@33090|Viridiplantae,3GA5G@35493|Streptophyta,4JDX3@91835|fabids 1.0 2759|Eukaryota 1.0 G 1.0 Belongs to the phosphoglycerate kinase family 1.0 - 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N,MS_channel,PGK,TM_helix,Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 94921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378330 0 0 0 0 255592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIDLSADKVTR MGYG000003266_01673;MGYG000001636_00165;MGYG000002050_01400 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CVME@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 753134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIDNSFNVLR MGYG000003992_00508 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__43-108|s__43-108 sp001915545|m__MGYG000003992 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2811730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIDNSYNVLR MGYG000002935_00389;MGYG000000243_01847;MGYG000002478_01470 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 3719423 3844850 8496644 4800101 7087359 4216831 4210172 3732747 3863857 3060951 3409161 5113317 7135112 3973395 3680258 6622385 4711156 3233369 3206662 3666729 4472593 3766383 1087682 5391493 3617263 5217826 4122965 3518976 4357652 3761267 8802384 5118806 9236493 3217356 3778220 4405834 3689739 9763129 2433374 1678497 2727467 2720078 3800573 2055294 1981447 2441308 2497567 2525792 2504416 2426724 6035455 2249857 2666510 3958515 2185938 1846227 2286894 2461057 2122289 2182327 2579692 1667390 2019742 2717801 2551022 2234148 2392523 2182310 1978013 2443720 2804867 2041057 2247623 2460874 2656884 2292365 1744651 1299798 2166101 2043586 3796616 2655001 2626074 1435106 2683532 1861010 2015980 2675917 4393698 2595726 2360489 3191771 1983623 3281567 1697317 1739585 1746285 1326049 2809228 2368354 2014924 1945454 1650114 2728317 2272842 1786500 3065975 1454204 1534456 1348634 1860631 2366145 2369824 2004076 533067 949930 781949 0 711017 427577 408006 0 376773 0 147610 569603 0 0 1177954 0 1050265 558904 0 0 0 326460 0 532733 623783 374125 0 921994 0 0 401852 431270 516112 0 380962 0 0 904054 2370688 1434728 625434 1906418 4618879 2242870 0 2350760 2190454 701141 1401142 1824251 5739766 1328268 1450319 3228456 1886080 3806515 1884590 2614373 1319637 2229020 3700462 3069086 1716185 1894495 1495108 3402421 2050480 2364309 2288413 1709880 1030551 2046645 2664495 1732122 2481079 2065146 -AAIDSGVC(Carbamidomethyl)VVAEEDGVIENVQSDKIVVKAK MGYG000003149_00719 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA4285|s__UBA4285 sp900542465|m__MGYG000003149 1.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,25V1J@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 - 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133650 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390527 0 734781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433000 0 1726979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIDSGWLSADHQVGQTGK MGYG000002287_00701;MGYG000002287_01182 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Butyricicoccaceae|g__Agathobaculum|s__Agathobaculum sp003481705|m__MGYG000002287 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,36DD9@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1209396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIDSLGASD(Cation_Na)DAAAEDTDAK MGYG000001338_01847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,NAD_binding_7,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 979504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIDSLGASDDAAAEDTDAK MGYG000001338_01847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,NAD_binding_7,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 1058225 3737387 1318763 981136 2349883 1014437 618632 1280685 0 1593389 2524518 1200598 1084131 840834 1865570 1260764 0 2396306 0 1180493 0 987598 1914993 702503 1538100 914746 1054124 2586921 429362 1083608 1381912 3804767 1044763 938734 0 914391 688685 1371760 884437 6341591 598522 710210 977256 578397 973244 1104327 0 482661 1030053 577028 463428 503294 672505 178121 0 7347785 0 853843 0 0 3325442 1081990 455125 651466 868214 5754120 920273 666321 6167629 2535459 0 1044302 0 545192 433053 358208 1370308 7217665 1325487 1115995 571408 689808 891012 1083402 0 807337 845719 1873572 906141 836851 1166143 892345 0 928823 0 964152 0 1368425 1110734 490622 1103261 1037183 1215752 1173803 640239 1804510 1767273 7136822 1953613 1276632 0 0 809548 1450541 771907 10028342 1206690 900051 2469696 842488 953062 743807 0 1141151 1781571 922194 1130213 1109798 0 1256435 0 1832454 0 453495 0 1141767 419787 1204083 0 477879 871506 1936933 730175 834806 6562928 4054022 1303397 0 0 619492 356629 1717739 839328 13977823 3540648 864878 1255205 849184 1416204 1073003 0 688448 1482185 1333305 1617330 1406794 967264 2150712 0 2022217 0 578432 0 1070245 4923774 1818534 1115492 793350 894895 4813832 933131 916103 6307152 9305236 8715415 1077592 0 988478 921247 3567843 -AAIDSLGTDAEATTDDADAEATDDTAADDTAETTEEAAE MGYG000000171_00799 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 1.0 186801|Clostridia 1.0 M 1.0 Cobalt chelatase (CbiK) 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1944077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIDSLGTEAATEDEAAEAETAEAETEAAEE MGYG000000133_00237 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 1.0 186801|Clostridia 1.0 M 1.0 Cobalt chelatase (CbiK) 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Metabolic pathways;Porphyrin metabolism 1.0 none 1.0 0 232331 199790 0 224846 118784 111008 0 255206 0 0 0 0 0 0 0 0 0 0 0 0 96066 0 202606 0 0 0 0 0 0 0 221037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162043 0 184964 0 0 339875 0 0 0 193669 0 0 0 0 258540 0 0 0 0 0 0 0 0 0 397066 217676 0 0 257619 0 0 204145 179815 0 0 0 176544 0 50146866 50782004 50725594 71978729 5485583 32011924 63564190 0 43225411 94894886 0 0 0 0 69144479 0 83198303 0 0 0 0 64425109 0 43421473 92948245 27877691 81161139 0 76895601 0 0 96309191 175436804 0 0 0 101277954 17947143 -AAIDSTDAENMSDADVDKIK MGYG000000018_01360 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus|s__Coprococcus eutactus|m__MGYG000000018 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 975513 0 0 0 0 1084712 0 0 0 0 1267409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192038 0 0 0 0 0 0 0 0 0 563256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEAAGGKIEE MGYG000002506_02942;MGYG000002494_02450;MGYG000002515_03184;MGYG000002323_00405;MGYG000002366_00455;MGYG000002534_00411;MGYG000002535_04680;MGYG000002477_00168 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,3XPK7@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 3844799 3098485 3560775 2946774 2659633 5088603 4797686 4017637 3303904 4119090 3012006 2878460 2216551 4635533 2909155 2050521 3464964 0 3309368 3402298 4001667 4303639 0 7219235 4242979 4369307 4230152 0 4284681 4506950 3563333 3906332 3471305 0 4945461 3351968 3660881 3295667 8662406 8325992 8290125 6590211 6917722 15947003 7969561 8218993 9036650 10805916 3223089 6545578 3914349 8452059 7783434 5938759 9363486 0 8249478 6432926 9789327 17750167 0 12698911 10246048 7194236 6929169 0 11964607 9542128 3964632 5897493 8485397 6625609 7294107 6803822 7662577 9048630 4037929 2867990 4623069 3197008 4681564 7558232 4092513 4466535 4007540 4916615 3290641 2806962 3928464 3671222 3036617 3826625 3682451 0 3060986 3529449 3904649 6774246 0 7382901 4329176 3904551 3149146 0 3181307 3520862 3700804 3076933 3418965 4564490 2546748 3846722 2638414 3295202 5574170 5452338 5071127 4358038 4276324 6295092 6770286 7020447 4080348 7843447 4073875 5317974 6355033 5050873 5306423 4974418 4626526 0 4711696 4770582 6259278 6930627 0 5054681 6250268 5311684 4938519 0 4391510 5598116 3382659 4922483 5124772 9945444 8137067 7489515 4383501 3743630 0 286184 187061 0 0 0 0 170401 0 0 0 0 278651 0 0 145934 0 0 0 0 0 0 0 206867 0 106139 0 0 326465 1014524 0 0 0 0 0 0 0 0 -AAIEADRYLQQL MGYG000002960_00851;MGYG000003697_02811 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 415148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 658721 0 482541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEAER MGYG000002478_04055;MGYG000003351_01292;MGYG000001306_03156;MGYG000002218_02990;MGYG000002438_02820;MGYG000001346_01037;MGYG000002549_00642;MGYG000000224_00060;MGYG000000098_03753;MGYG000004797_00961;MGYG000003701_01280;MGYG000000105_01246 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia,4AM3W@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 C 1.0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1629760 0 0 0 0 0 0 0 0 1673394 0 0 0 0 0 0 0 0 0 0 0 1770318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2415208 0 0 0 2687486 0 0 0 0 0 0 3390882 0 0 2551841 0 3744487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1041901 0 0 0 0 0 0 0 1160340 0 0 0 0 1315263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 725544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1824909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2133878 0 1366271 0 0 1370236 1720544 0 0 0 0 0 0 -AAIEAGANDFIQKPLNAEQIHHIISSR MGYG000002517_01575 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG4753@1|root,COG4753@2|Bacteria,1VAG0@1239|Firmicutes,24P6B@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 cheY-homologous receiver domain 1.0 - 1.0 - 1.0 - 1.0 ko:K03413 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 HTH_18,Response_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 314271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163694 0 170004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208552 0 246326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 556751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364536 0 483635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEAGC(Carbamidomethyl)R MGYG000000016_00642;MGYG000000177_00366 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum 1.0 COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,36EW0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 pyruvate flavodoxin ferredoxin oxidoreductase domain protein 1.0 vorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00174 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFOR_II,POR_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 2621906 0 1866226 0 0 2339495 0 0 0 0 0 0 0 2043844 0 3295288 2204768 3429675 3214612 0 2048199 3181270 0 2182657 0 1671360 2890754 0 0 0 0 2661785 0 0 0 0 0 0 637815 0 694891 0 0 681022 0 0 0 0 0 0 0 584781 0 593861 173864 351745 843384 0 744075 468150 0 286737 0 533540 562736 0 0 0 0 436870 0 0 0 0 0 0 1122260 0 1586514 0 0 1912550 0 0 0 0 0 0 0 655837 0 3476725 4149633 1316856 2339159 0 2218993 2057022 0 2547135 0 2295443 2211262 0 0 0 0 1989083 0 0 0 0 0 0 105107 0 250182 0 0 294570 0 0 0 0 0 0 0 248079 0 1193315 571656 119516 536784 0 643983 302964 0 168821 0 526950 163017 0 0 0 0 603874 0 0 0 0 0 0 1228957 0 137166 0 0 756039 0 0 0 0 0 0 0 552188 0 345366 355537 606019 431444 0 286131 1096861 0 1197571 0 895194 315852 0 0 0 0 1117410 0 0 0 -AAIEAGISVYNR MGYG000004296_01202;MGYG000004733_01556 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia 0.5 186801|Clostridia 1.0 E 1.0 methionine synthase I, cobalamin-binding domain 0.5 acsE 1.0 - 1.0 2.1.1.258 1.0 ko:K15023 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R02289,R10243 1.0 RC00004,RC00113,RC01144,RC02871,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pterin_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the N(5) group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein.-!-Involved, together with EC 1.2.7.4 and EC 2.3.1.169, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea. (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein] = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2018584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEAGK MGYG000000262_02231;MGYG000001300_02035;MGYG000000205_00404;MGYG000001065_00276 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,21Z3N@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 E 0.5 BMC 0.5 pduB 0.5 - 1.0 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 1.0 - 1.0 - 1.0 BMC 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.5 0.5 0.5 0.5 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEAGNEDAK MGYG000004733_01879 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 614300 0 1498465 0 0 1549406 0 0 0 0 0 0 0 769494 1187349 0 0 2123544 0 0 1056607 2139050 1496182 1090891 0 632941 0 1489666 0 0 973481 0 1424031 0 0 0 748936 1621371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 941721 0 326211 0 0 1097895 0 0 0 0 0 0 0 1154065 1646873 0 0 338716 0 0 846437 2047659 668542 823333 0 1727529 0 901128 0 0 1125068 0 873473 0 0 0 872072 427639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390557 0 0 173295 0 0 0 0 0 0 0 270967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488547 0 932095 0 0 0 0 323883 -AAIEALPAK MGYG000000098_01032;MGYG000002560_00984;MGYG000002455_00337;MGYG000004797_02626;MGYG000000243_02802 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 2E3DE@1|root,32YCK@2|Bacteria,4NVFG@976|Bacteroidetes,2FT26@200643|Bacteroidia,4ARB3@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 S 1.0 Stress responsive A B barrel domain protein 0.8 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Dabb 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1767385 1760937 2253802 0 2524243 2167723 1853647 1443430 0 0 1757913 1570702 2341242 0 0 2825606 0 2022764 0 0 0 2011660 1774575 2409729 1641738 1857537 1783926 1962095 1655585 0 0 0 2392308 0 1698348 1752706 1998312 2895264 1459879 1230164 1294896 0 1418633 1436880 1654322 1436187 0 0 2614958 1657196 2382505 0 0 1722310 0 1180826 0 0 0 1260464 1385553 1732939 1672649 1622369 1417702 1169787 1764524 0 0 0 1521368 0 1931656 1676327 1548654 1569240 1454728 1299870 1775265 0 1842516 1438347 1493138 1288173 0 0 1433365 1015506 1572681 0 0 1681940 0 2499553 0 0 0 1339725 1963820 1529483 1780876 1119847 1403108 2046986 1256816 0 0 0 1155629 0 1628430 1428137 1382141 1369955 1185101 1016903 1221001 0 1122662 1185543 1572883 841504 0 0 11801085 1448360 4528110 0 0 0 0 713323 0 0 0 1559067 505216 1569603 902515 959738 1333225 1187582 1755589 0 0 0 1057510 0 1131096 1266488 1206620 1325293 1354566 998026 1265625 0 1932064 1484952 1413924 1739490 0 0 1748471 1291310 1252250 0 0 1227860 0 3191571 0 0 0 1350030 2841350 1095614 1347706 1953295 1049850 2204603 1354445 0 0 0 910868 0 1096447 1126407 209847 1166787 -AAIEAVK MGYG000000196_00058;MGYG000002033_00995;MGYG000002549_03488 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1454@1|root,COG1454@2|Bacteria,4NIU1@976|Bacteroidetes,2FMAN@200643|Bacteroidia,4AKAE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 fucO 1.0 - 1.0 1.1.1.77 1.0 ko:K00048 1.0 ko00630,ko00640,ko01120,map00630,map00640,map01120 1.0 - 1.0 R01781,R02257 1.0 RC00087,RC00099 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lactaldehyde reductase. propanediol oxidoreductase. - (1) (R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + H(+) + NADH. (2) (S)-propane-1,2-diol + NAD(+) = (S)-lactaldehyde + H(+) + NADH. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Propanoate metabolism;Glyoxylate and dicarboxylate metabolism 1.0 none 1.0 0 0 0 970277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEE(Cation_Na)GIVPGGGVAYIR MGYG000004876_02137;MGYG000002478_00380;MGYG000003363_02977;MGYG000002171_01748;MGYG000004763_01826;MGYG000002470_00024;MGYG000000243_00634;MGYG000002455_00111;MGYG000001346_02504;MGYG000002933_01569 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEEGIIPGGGVAYIR MGYG000001433_02375;MGYG000001345_00379;MGYG000002281_01780;MGYG000002549_02837;MGYG000000013_01093;MGYG000003351_04147;MGYG000000196_04163;MGYG000001659_02186;MGYG000003252_04996;MGYG000003922_03103;MGYG000002275_02480;MGYG000000029_01790;MGYG000001378_04618 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 0.8461538461538461 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 4334899 4468299 3748537 5067697 3960971 3408217 7774027 6094129 6125975 6704547 9011093 4486045 3108029 4731522 4211847 4238475 5286877 0 4111242 4244864 4760624 2986059 7512123 5035975 4342413 5079658 4786881 5461922 5587225 5770025 6292727 5784232 3571616 5996763 4691598 5798802 5617474 2940432 1959349 1779257 2132593 2582538 2625421 2968169 2060255 2221748 1995399 3124535 6410403 2360663 2372317 2639130 3462169 2375245 2902615 1169052 2278943 2095639 2241892 3550485 1920265 2955477 2780541 0 2448991 1376424 2480611 2318623 1922412 3580911 2012861 2086724 2352656 1735750 2305381 2196332 1683632 1468817 2803975 1528692 2575451 2540121 1953648 1500501 2424365 1354547 2723331 1507292 1411917 1327705 1494747 1555011 2145850 3080637 1269464 1243583 1280526 1484463 2480982 2480648 1591543 1843758 1588154 1590340 1671228 1737189 1665103 1356397 1959230 1353433 1670438 2195553 1554852 2742232 1912937 1936634 2074853 1761285 2295112 2837539 2206297 2531994 2102697 2547430 3371987 2176375 2732033 1952905 2105422 2363600 1850171 6831373 2058639 1685473 2271728 0 9703114 2617546 2524276 2984223 2388901 6960990 2204320 2256900 2194125 2205465 2518623 2400891 2338535 2476349 2579444 2300169 1022498 1108451 880887 1655193 1322440 1963211 1227312 1182477 1569597 1088663 2631545 803624 2050862 658254 980116 1109290 1378935 975096 831303 1451890 833307 1232493 799444 1515972 1217015 1552550 885156 901587 934845 1450256 1137454 1732641 578346 1323677 1383227 1351129 2493723 1340211 -AAIEEGIVAGGGTTYIR MGYG000002834_01380;MGYG000001056_01919;MGYG000003697_01689;MGYG000002293_01257;MGYG000001770_01876 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 130495 212514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196037 0 0 0 0 0 0 0 0 237807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1384085 1404440 2474687 986783 1374408 2118802 1348679 0 0 0 2706752 0 0 0 0 1446056 0 5408568 0 0 0 2170599 9456250 2406795 1037984 1390476 0 4998821 1123746 0 1209372 1438147 1880994 1644896 0 1282190 1239032 2042071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79244 0 0 0 0 -AAIEEGIVPGGGVAYIR MGYG000004876_02137;MGYG000002478_00380;MGYG000003363_02977;MGYG000002171_01748;MGYG000004763_01826;MGYG000002470_00024;MGYG000000243_00634;MGYG000002455_00111;MGYG000001346_02504;MGYG000002933_01569 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 15219614 16720469 25156426 20943299 21378969 15279702 19609392 17674046 17532708 18822133 20790467 18553768 23508013 14819157 12964666 20922494 22700086 20413386 16594090 13944760 14204038 12324109 24909334 18483895 13609123 0 18029280 27800895 16107245 19097755 28343248 19674541 21725838 13272326 16257768 17308623 14453302 21683981 0 0 7601388 8185981 11682133 8546449 5835361 8391295 7141163 9141513 10681095 8641613 17247700 7948635 8098470 12794013 11958444 0 7198975 7978935 8015456 9012973 14753966 6692225 7874722 7338912 8726791 0 8633999 7944165 8140288 10558933 9815543 6739491 6689575 5993155 7032266 0 7909972 6612142 9203912 7665063 15301624 10785218 9761803 7623076 10579461 8634254 13405869 11131598 14045251 8531865 6943463 10527110 9807575 20930856 7614935 6818584 6818195 6800915 18326095 9934417 7501654 9174360 7210767 13287820 7674339 6709961 13309449 6718446 6998724 6366537 9039179 10977446 9701214 9332862 2307137 2109483 2349332 2447973 2195647 0 2213198 2982927 0 3239589 3936612 2720369 2840650 2267690 2279960 2695359 1979383 0 2932462 1599517 0 1887594 2208034 0 2585295 2281238 2988961 2348221 2079564 2499638 1958707 2233252 0 2595955 3455755 2585085 2186408 1854187 3911090 3517464 3646368 4587311 7650006 5590155 3955856 4389105 4207375 2560375 9968856 3557164 10611974 3289360 3692122 6868811 4039017 10594012 3619210 5006756 2795507 4115982 10704213 4761321 5182064 6004519 3774815 9437338 3998194 5099723 4886536 5321992 3897123 4968072 5000350 4091630 5287377 4425304 -AAIEEGIVPGGGVT(Thr->Ala)YIR MGYG000001787_00205;MGYG000001306_00685;MGYG000001364_01313;MGYG000000236_02963;MGYG000001789_02329;MGYG000003693_01240 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3961644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEEGIVPGGGVTYIR MGYG000001787_00205;MGYG000001306_00685;MGYG000001364_01313;MGYG000000236_02963;MGYG000001789_02329;MGYG000003693_01240 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 96121 0 0 0 163976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 130795 0 214880 0 0 194684 1208929 509207 1237232 1641279 0 1252218 0 1886580 1579298 2376846 2194480 1427699 1156965 1724891 1925920 0 1626441 12846077 1104539 1059009 0 1268119 21768139 865591 1548726 1947703 1775577 14939965 1458715 0 1067069 1364446 1145456 1442282 1536815 1299492 1701195 1073386 0 0 0 0 0 0 0 0 137652 0 0 0 116111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316602 0 0 201222 0 0 0 0 0 0 0 0 348957 0 0 0 0 0 0 0 0 0 0 0 497219 0 0 3161542 0 0 0 0 3227084 0 0 616607 116569 2861633 0 0 513408 0 0 714394 241817 0 0 0 0 0 989497 0 0 1039170 0 0 0 168969 0 0 0 0 172503 0 0 0 0 0 0 0 0 359217 0 0 0 0 0 0 0 0 153838 0 0 0 0 842106 -AAIEEGLLPGGGVALVQAAAK MGYG000003683_00853;MGYG000000756_00212;MGYG000003730_00164;MGYG000001292_00715 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CZJK@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 130408 0 455225 0 183097 0 0 0 0 281946 208080 0 571970 0 0 681639 0 126882 0 0 0 0 0 0 98763 94134 0 191747 172233 0 0 0 0 0 0 0 0 270629 713872 862356 793460 993269 901761 1322411 914131 771639 0 688421 646947 0 2371683 540647 0 1023893 0 4744848 0 688282 0 773276 1654687 2446724 1337975 592978 866717 3338174 1126397 0 1690428 0 920180 0 0 861736 1109334 5706378 1397376 1468762 0 168788 0 162702 257751 971052 0 0 0 0 709580 0 0 1761975 0 0 0 1095532 0 1274703 0 170915 285032 0 0 1010113 0 0 0 0 3214890 0 0 0 0 187422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151898 0 0 0 0 0 0 150173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 501677 0 0 0 64679 0 0 0 0 0 274231 0 0 0 0 0 0 0 30905 156382 0 0 368265 75885 0 0 0 0 0 0 0 0 0 0 0 -AAIEEGTVPGGGVAYI(Xle->Tyr)R MGYG000003521_02097;MGYG000000355_02196;MGYG000003251_00039;MGYG000002218_01379;MGYG000000044_03505;MGYG000002033_00862;MGYG000002438_00745;MGYG000000174_04760;MGYG000000138_02067;MGYG000001489_00629;MGYG000003338_01836 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22WR5@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEEGTVPGGGVAYIR MGYG000003521_02097;MGYG000000355_02196;MGYG000003251_00039;MGYG000002218_01379;MGYG000000044_03505;MGYG000002033_00862;MGYG000002438_00745;MGYG000000174_04760;MGYG000000138_02067;MGYG000001489_00629;MGYG000003338_01836 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22WR5@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 705679 736810 608208 913729 737917 681287 995857 1041621 715134 736904 0 991095 584185 690802 630600 810707 943198 762856 684769 880000 846625 581897 1016734 897147 634602 762626 952357 722697 598516 1026894 1106683 1008026 772317 953475 511543 954307 641794 540077 844868 1012828 1002363 721907 1269523 976360 828534 1177093 755939 1291278 0 2697053 1047428 942229 903690 1364109 1347848 740391 826540 802719 4035618 1133976 805873 1058799 942009 1026544 1061547 741890 1250636 2352484 760391 2389575 1028079 899192 898073 909626 1018024 907948 1122929 1668183 1531934 919866 2232029 1773947 1585042 1246812 1568546 1522229 0 0 1548959 1212733 1212181 1322127 1781211 1790756 1289468 977712 3374818 1101915 0 1513817 1288697 1690812 1240822 1873539 1278874 2327705 0 1920941 1143183 887441 1272428 1552766 1630700 1338533 1438754 2302891 1613800 1140925 2080553 1508886 1545444 1476414 1274828 1528994 0 2348959 2000934 1220787 1382478 1810893 1430403 1481235 1500680 919597 5539800 1384013 2132250 1538258 1622988 1506545 1249784 1480745 1546814 2816812 2041185 3109548 1587003 2033664 1521098 1678589 1293257 1260875 1999245 2547196 2182933 2641915 3665154 2745866 2183902 2160153 2237050 2703540 0 5599430 4554121 1761178 1639334 3085816 2529986 3692320 1754575 2258840 8103367 1834607 3300361 2073976 2425508 2073760 1980187 3036743 2422049 7517469 2268812 5772572 1708341 2463945 2320452 2315293 2621012 2295517 -AAIEESK MGYG000000077_00225;MGYG000002517_01578 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,25WFS@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 E 0.5 Periplasmic binding protein 0.5 braC 0.5 - 1.0 - 1.0 ko:K01999 0.5 ko02010,ko02024,map02010,map02024 0.5 M00237 0.5 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 0.5 3.A.1.4 0.5 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 0.5 none 1.0 0 0 0 0 0 0 0 0 153569 186509 0 0 0 0 208664 0 0 0 0 0 99431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54427 428508 0 0 0 0 204510 0 463714 0 0 0 108862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290425 269335 0 0 0 0 119602 0 0 0 0 0 515251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199048 0 0 0 0 244626 0 658579 0 0 0 1429499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEFLR MGYG000002279_01754;MGYG000001319_00092;MGYG000000067_01247;MGYG000003355_01546;MGYG000000154_01998;MGYG000004735_01120;MGYG000003012_00855;MGYG000002966_02852;MGYG000000164_02267;MGYG000000404_01946;MGYG000000287_02964;MGYG000000806_00684;MGYG000002025_01407;MGYG000000133_02455 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3XYYG@572511|Blautia 0.2857142857142857 186801|Clostridia 1.0 G 0.8571428571428571 Belongs to the GPI family 0.5 pgi 0.8571428571428571 - 1.0 5.3.1.9 0.8571428571428571 ko:K01810 0.8571428571428571 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 0.8571428571428571 M00001,M00004,M00114 0.8571428571428571 R02739,R02740,R03321 0.8571428571428571 RC00376,RC00563 0.8571428571428571 ko00000,ko00001,ko00002,ko01000,ko04147 0.8571428571428571 - 1.0 - 1.0 - 1.0 PGI 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 0.8571428571428571 none 1.0 0 0 0 0 0 0 764660 0 0 0 0 0 0 0 600674 406388 0 2011364 0 628567 0 0 2570631 0 0 0 0 1954669 0 0 0 0 0 0 1083160 0 0 0 0 0 0 0 0 0 0 0 0 0 123525 0 0 0 0 0 0 241943 0 0 172499 0 503043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100268 0 0 0 0 105551 0 0 0 149592 0 0 0 113340 113264 0 0 0 86072 0 0 232220 0 0 0 0 341977 0 0 0 328246 0 0 110684 0 0 133505 0 332140 123161 264967 0 0 239329 0 0 0 325247 0 0 0 99805 327139 0 116450 0 113069 251360 0 488507 0 0 0 0 461103 0 0 0 272914 249101 0 112885 92260 0 194796 0 2547187 2904245 4481125 0 0 2824461 0 0 0 2134848 0 0 0 0 2149336 0 295002 0 400528 2401479 0 686536 0 0 0 0 780879 0 0 0 2796594 4218761 0 1459502 2325495 0 1962378 -AAIEGAVAK MGYG000000357_00601 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-873|s__|m__MGYG000000357 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,22VY9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1352453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEGTTVEIAAK MGYG000001292_00243 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4D0P9@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplI 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02939 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L9_C,Ribosomal_L9_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 133650 0 0 190381 0 0 0 0 271272 0 0 543477 0 381112 0 250570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 873120 0 0 935889 498631 0 799870 0 0 0 0 1920922 0 0 1318943 0 2250920 0 854149 0 203367 0 799953 0 0 761306 1084757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217728 0 0 428054 0 0 0 0 0 288447 0 0 0 0 259256 171101 0 0 0 0 0 0 0 0 0 0 0 393525 0 0 479927 902113 0 344071 0 0 0 0 311519 0 0 654508 0 423386 0 440785 0 482167 355501 392620 0 0 345936 492502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEHGMK MGYG000000084_01029;MGYG000001627_01339;MGYG000001761_01983;MGYG000000573_01504;MGYG000004866_02019;MGYG000003921_00370;MGYG000001157_00690 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3WIYT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429235 0 0 0 0 298381 0 0 0 0 378105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139078 0 0 0 0 645197 0 0 0 0 970462 0 875431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 773476 0 0 0 0 113120 0 0 0 0 907969 0 235954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1431643 0 0 800595 0 2204622 0 0 0 0 800599 0 604572 0 0 0 0 0 0 0 0 -AAIEIM(Oxidation)EADPSKFVHR MGYG000000243_01845;MGYG000002171_01133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEIM(Oxidation)EANPDKLIHR MGYG000002478_01472 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEIMEADPSK MGYG000000273_00482;MGYG000000243_01845;MGYG000002171_01133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2477052 0 4385415 3002602 2978150 2099730 3738664 2439133 2925653 1991703 2096176 1986326 2343871 2114034 2023016 1841482 1998445 1548519 2147108 2195016 2417007 1943071 3033211 3789093 1862800 2714912 0 2250878 2341381 2635939 5039847 2285427 6404082 2763826 2249178 3247810 2476684 5402570 1307693 0 1291717 999249 1331531 1172082 814468 1260911 941514 952850 1226315 1084518 1889335 973029 885882 1739438 928807 830517 856386 818667 996658 757189 706525 853108 794493 936682 0 1064401 658501 999736 832299 1203222 1424310 945269 903821 1091867 948112 1308385 1387334 0 1635810 1566570 2570926 1719506 2243152 1249470 1996012 1270717 1905187 1876045 2173236 1637119 1229887 1681406 1730325 4083091 1107377 1188582 1595548 1338028 3300416 2263032 1193306 1743518 0 2262478 1974952 1735670 2167635 1091228 1265506 783164 1829649 2062003 1552412 1856280 534743 0 0 0 198194 0 0 0 401779 0 0 0 0 329737 0 0 0 0 0 0 0 0 0 539230 538179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334904 0 0 0 301349 0 230629 314298 0 348262 0 328123 224856 0 0 0 0 0 403040 0 304096 518942 0 165769 0 0 0 367123 0 0 0 0 0 287700 188848 293612 -AAIEIMEADPSKFVHR MGYG000000243_01845;MGYG000002171_01133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 1400361 4388302 0 2213016 1324185 0 0 1339033 0 0 820271 1625437 1187487 0 1173901 1488165 0 0 1060967 0 777876 0 1181337 0 0 856449 0 0 0 2800136 0 4657482 1303653 1052492 1023177 0 4080240 0 71993 91611 0 285235 116767 0 0 39710 0 0 63930 303187 81051 0 286518 54235 0 0 48619 0 176421 0 152511 0 0 50889 0 0 0 70418 0 249242 0 147924 69060 0 168806 0 735840 604087 0 707313 466105 0 0 242380 0 0 203423 818583 286410 0 719098 455662 0 0 560614 0 506512 0 573186 0 0 555663 0 0 0 371594 0 497562 443853 870809 262498 0 357829 0 110572 0 0 182433 0 0 0 179451 0 0 0 0 611460 0 0 717111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 634054 591921 0 0 0 0 0 0 0 224247 0 0 0 0 0 0 0 294315 0 0 0 0 0 0 0 0 278073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89916 -AAIEIMEADSTK MGYG000002438_03364 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 455464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1205088 0 0 0 0 0 0 0 0 1191639 0 1831269 0 0 0 0 0 0 -AAIEIMEANPDK MGYG000004797_02539;MGYG000002478_01472 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 965137 0 445519 805055 407342 0 0 578723 764067 0 615710 756732 522633 576577 592692 811272 0 495537 566744 814664 0 0 293182 0 713583 674181 720576 411491 0 823071 0 573821 620602 0 664659 722333 573806 464471 810126 0 1378419 815100 960980 0 0 1004274 669090 0 927751 765758 2404247 746952 712404 2859504 0 722750 733617 735203 0 0 782132 0 835507 801565 907518 564709 668754 752246 0 1727689 1021740 0 962395 656749 681984 2040271 0 0 318972 0 435700 0 0 351936 0 0 0 675148 883230 0 247747 0 0 378829 0 188110 0 0 409156 0 275377 0 0 645658 512072 0 0 0 1154884 0 0 0 0 708274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224960 0 0 0 0 0 0 0 0 0 650315 0 0 0 0 0 0 0 0 0 0 0 0 0 361811 400203 0 0 876925 0 0 0 383775 0 0 0 468705 0 1798432 0 472051 0 0 1763075 0 0 714118 325324 1638253 292727 808639 0 0 0 0 496754 371982 430667 0 -AAIEIMEANPDKLIHR MGYG000002478_01472 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1279933 1223710 1158439 1466448 1282170 1164341 1264800 984003 1230442 1054233 940105 1173556 1588389 1177704 969661 1725973 1412876 926927 1351639 1075631 954159 917911 1200313 1329861 960704 1159051 1228756 1005370 1163789 1122009 1840200 1396642 1393707 581535 1312879 0 1227506 1128558 502764 486469 867264 737993 1017808 850441 600536 946080 604554 637851 1055690 901544 1007015 663422 854024 1575546 708364 470124 635248 577435 832567 1088104 360461 617674 660977 693911 640833 395102 636520 712094 735789 785560 577339 409102 656463 519213 461296 740680 575234 451810 668304 584813 1077039 749650 772845 501161 427124 539516 765530 884230 747410 526016 547086 776434 534743 945993 737622 549356 559934 479471 867432 689960 424057 617855 475557 638744 620311 420831 854711 520367 494549 304270 518158 684450 501983 599099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53590 0 0 0 0 0 0 0 0 0 0 0 0 0 1020295 845556 936997 1077133 1601527 1428099 920089 1267832 1463689 639546 806740 951267 1287393 848551 1082254 1569306 1309220 1224844 1177143 1179503 765283 964509 1143998 956844 915947 1107934 1236898 1208193 1453989 1256258 1192635 1166646 542650 1204849 1261454 966488 1311453 1204270 -AAIEKKPIK MGYG000001315_02437 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,21YF6@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Metabolic pathways 1.0 none 1.0 0 41381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEKYPNLSK MGYG000000187_00761 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,25VAF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3334382 0 0 0 0 3004521 0 0 0 0 2711551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 567966 0 0 0 0 224903 0 0 0 0 317244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516308 0 0 0 0 86717 0 0 0 0 104858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIELMK MGYG000000089_01040 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WHJX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 698529 0 0 0 0 0 0 0 0 0 944070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213664 0 0 0 0 130330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIENASNK MGYG000002126_00706 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__UBA1390|g__UBA1390|s__UBA1390 sp900764045|m__MGYG000002126 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,36DJ7@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1605058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1779092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIENMTGLK MGYG000002528_00065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 protein conserved in bacteria 1.0 asp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Asp23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 567758 0 0 0 398446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313815 0 146379 0 0 0 0 298013 0 0 321937 0 0 0 0 0 0 0 590009 0 0 0 313066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100947 0 432628 0 0 0 0 339474 0 0 299013 0 0 0 0 0 0 0 1283512 0 0 0 907784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1881488 0 777185 0 0 0 0 4190352 0 0 1445837 0 0 0 0 0 0 0 259405 0 0 0 582004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 959276 0 0 0 0 1078996 0 0 300677 0 0 0 0 0 0 0 273060 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208816 0 0 172878 0 0 0 0 0 0 -AAIEPALEYLR MGYG000001315_02715 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG4134@1|root,COG4134@2|Bacteria,1TR3G@1239|Firmicutes,24A5K@186801|Clostridia,36E1C@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 S 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K02055 1.0 ko02024,map02024 1.0 M00193 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.11 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 339395 1213030 0 0 0 0 570521 0 0 0 0 0 0 0 0 0 0 0 446538 0 0 0 0 0 0 0 0 0 0 0 0 663893 0 0 0 0 1016900 0 1146635 885643 0 0 0 0 998387 0 0 0 0 0 0 0 0 0 0 0 1100171 0 0 0 0 0 0 0 0 0 0 0 0 1012793 0 0 0 0 1023974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249321 208210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 615891 0 0 0 0 0 0 0 0 0 0 0 0 598176 0 0 0 0 868145 0 222162 417280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 473543 0 0 0 0 0 0 0 0 0 0 0 0 376543 0 0 0 0 367649 -AAIETALGK MGYG000000003_01212;MGYG000001302.1_00819;MGYG000001562_02334;MGYG000001546_02855;MGYG000001420_01443 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,22UA3@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 5527891 0 1987746 4552940 2132695 3519748 6280437 0 6587358 3338343 0 3415902 0 0 4471895 2117857 0 0 8994461 7648559 6153549 2577033 0 0 4481795 6150113 4482914 0 4293750 4717531 0 3203799 2265515 2405812 5199928 4994927 6644624 0 2028521 0 1837521 0 1510497 0 1664053 0 1887910 1733921 0 0 0 0 1761666 1520431 1904304 0 2616337 2137538 1323476 1138420 0 1334082 1930001 1944035 1862641 0 851156 1276047 0 0 0 2166626 1619657 1807443 2065932 1461670 0 0 2102690 1564499 1669166 1730590 0 0 2527549 1983612 0 1339783 0 0 0 0 1327157 0 2316935 2429900 0 1441628 0 1416024 1821511 1442848 1857622 0 1521027 0 1698854 1531291 0 2203606 0 2416048 0 1779292 3250938 0 2398818 3435705 6409038 10022519 3628296 0 4644101 2793025 0 2894316 0 0 3871569 5703904 3591963 0 4435898 3540505 1972457 1765422 0 1873165 4153387 4195589 3451968 0 4602782 2675636 4900092 2529529 2281428 3249158 2863107 3218053 3584956 2216901 2560237 0 2276734 2284222 6256437 3251397 1577338 0 2112033 3308452 0 7189225 0 0 1921993 4036885 3064401 0 2426594 2707074 8035468 3179744 0 2220242 2009962 0 1876460 0 2743959 5900877 3063893 6440917 1673112 2590924 2390707 1566153 2332715 2897599 -AAIEVER MGYG000000243_01362;MGYG000002171_00772 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia,4AM3W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 none 1.0 0 0 3170007 0 0 0 0 0 0 0 0 0 1686121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2117961 0 3565790 0 0 0 0 3723732 0 0 583323 0 0 0 0 0 0 0 0 0 415623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546511 0 0 0 0 0 0 0 820360 0 0 0 0 0 0 0 0 0 1150564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 869236 0 554109 0 0 0 0 657838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336546 0 245564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172354 -AAIEVK MGYG000002528_02478;MGYG000001423_03022;MGYG000004594_00959;MGYG000002139_00077;MGYG000003291_00558;MGYG000000312_02404;MGYG000001615_00145;MGYG000000233_02503;MGYG000004785_01840;MGYG000000325_02351;MGYG000002098_00511;MGYG000004087_01282;MGYG000002590_00564;MGYG000001338_02151;MGYG000000179_00100;MGYG000002247_01703;MGYG000001646_00500;MGYG000003486_02360;MGYG000000184_00575;MGYG000004879_02866;MGYG000000217_00686;MGYG000002212_01829;MGYG000000198_00250;MGYG000000118_00274 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.25 186801|Clostridia 1.0 G 0.9583333333333334 Belongs to the PEP-utilizing enzyme family 0.5833333333333334 ppdK 0.9583333333333334 - 1.0 2.7.9.1 0.9583333333333334 ko:K01006 0.9583333333333334 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.9583333333333334 M00169,M00171,M00172,M00173 0.9583333333333334 R00206 0.9583333333333334 RC00002,RC00015 0.9583333333333334 ko00000,ko00001,ko00002,ko01000 0.9583333333333334 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9583333333333334 - 1.0 - 1.0 - 1.0 GT1 0.9166666666666666 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.9583333333333334 0.9583333333333334 0.9583333333333334 0.9583333333333334 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 0.9583333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 972812 1259958 0 0 0 0 0 0 4485051 0 0 0 0 0 0 0 0 0 0 0 0 1812029 2112209 0 0 0 2048854 0 0 0 2205087 2148922 9023051 3329222 3042354 0 0 0 1533919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3833003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEVKK MGYG000000184_00575 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A luti|m__MGYG000000184 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 503388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 795691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1017187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEVQK MGYG000001707_02428;MGYG000000231_00504;MGYG000001319_00729;MGYG000000280_02154;MGYG000000489_00801;MGYG000003694_01656 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8512094 0 0 0 0 8973365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3498165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1073927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIEYAIANDRDSVTLVHK MGYG000002506_00445;MGYG000002535_02428;MGYG000002494_01642 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,3XMJ1@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Isocitrate dehydrogenase 1.0 icd 1.0 GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114 1.0 1.1.1.42 1.0 ko:K00031 1.0 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 1.0 M00009,M00010,M00173,M00740 1.0 R00267,R00268,R01899 1.0 RC00001,RC00084,RC00114,RC00626,RC02801 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 1.0 CBS,Iso_dh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 isocitrate dehydrogenase (NADP(+)). oxalosuccinate carboxylase. Unlike EC 1.1.1.41, oxalosuccinate can be used as a substrate.-!-In eukaryotes, isocitrate dehydrogenase exists in two forms: an NAD(+)-linked enzyme found only in mitochondria and displaying allosteric properties, and a non-allosteric, NADP(+)-linked enzyme that is found in both mitochondria and cytoplasm.-!-The enzyme from some species can also use NAD(+) but much more slowly. D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;2-Oxocarboxylic acid metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Peroxisome;Glutathione metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 199053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236323 0 356611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994580 0 608242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316225 0 377573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 200551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 205873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 411695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIFGHDANWGR MGYG000000179_03146;MGYG000001619_00943 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,267WZ@186813|unclassified Clostridiales 0.5 186801|Clostridia 1.0 E 1.0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate 1.0 argJ 1.0 - 1.0 2.3.1.1,2.3.1.35 1.0 ko:K00620 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028 1.0 R00259,R02282 1.0 RC00004,RC00064 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ArgJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 amino-acid N-acetyltransferase. | glutamate N-acetyltransferase. N-acetylglutamate synthase. | ornithine transacetylase. Also acts with L-aspartate and, more slowly, with some other amino acids. | Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity. acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate. | L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L- glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 194287 0 0 165627 0 0 0 0 209508 75715 0 226158 0 162671 112446 0 116722 0 0 87859 147521 0 0 0 267497 269321 58418 0 230213 195658 0 0 0 0 0 73885 225226 0 161190 0 0 90641 0 0 0 0 56395 161338 0 122544 0 200881 69447 0 0 0 0 0 120163 0 0 0 200593 160945 50884 0 187904 0 0 0 0 0 0 100239 139835 0 247067 0 0 294929 0 0 0 0 226770 113002 0 301463 0 273942 280748 0 265074 0 0 222975 283880 0 0 0 86396 124969 241161 0 303603 208471 0 0 0 0 0 238214 154052 0 0 0 0 140125 0 0 0 0 0 96763 0 63248 0 0 0 0 92156 0 0 134959 0 0 0 0 0 246813 0 0 0 0 0 0 0 0 0 0 0 0 2093284 0 0 1848220 0 0 0 0 1671699 1673897 0 1286770 0 1959710 1498931 0 1411335 0 0 2127760 1462955 0 0 0 1312758 1964549 1937491 0 2342271 1820116 0 0 0 0 0 1637407 1936288 0 -AAIFNSPSK MGYG000002775_01545;MGYG000003266_01416 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CURX@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 alcohol dehydrogenase 1.0 adh1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIFPSKGEMR MGYG000002438_01503 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,2FN0B@200643|Bacteroidia,22VXJ@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) 1.0 tyrS 1.0 - 1.0 6.1.1.1 1.0 ko:K01866 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R02918 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 S4,tRNA-synt_1b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 tyrosine--tRNA ligase. tyrosyl-tRNA synthetase. - ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl- tRNA(Tyr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 993318 0 0 0 0 0 0 0 0 346039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353101 0 0 0 0 0 0 0 0 759011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055246 0 0 0 0 0 0 0 0 751953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825212 0 0 0 0 0 0 0 0 558688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1605480 0 0 0 0 0 0 0 0 2869770 0 0 0 0 0 0 0 0 -AAIGAAR MGYG000000179_05287 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Arabinose_Isome,Fucose_iso_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 95533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1640948 160186 0 0 0 0 671072 0 0 0 0 0 0 0 0 0 0 159401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111087 0 0 0 0 201490 0 0 0 0 0 0 0 0 0 0 127887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1176929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 528710 1572147 0 0 0 0 687187 0 0 0 0 0 0 0 0 0 0 329745 0 -AAIGAGIGIGR MGYG000002293_00140;MGYG000003697_01831 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3755648 0 0 0 0 4855740 0 0 0 0 4811255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIGEASDLR MGYG000001627_00478;MGYG000000084_00515 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3WHDD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 919157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511485 0 0 0 0 0 0 0 0 -AAIGEGDTLR MGYG000003937_02001 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3WHDD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIGEGLQAFC(Carbamidomethyl)IPGSVADHR MGYG000000245_00061;MGYG000002517_01686;MGYG000002492_01963 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 1.0 183925|Methanobacteria 1.0 F 1.0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 1.0 purD 1.0 - 1.0 6.3.4.13 1.0 ko:K01945 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04144 1.0 RC00090,RC00166 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 220441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162517 321755 0 0 302529 186176 323913 0 0 0 0 0 0 0 0 0 0 0 311486 0 410545 0 0 0 0 347990 0 0 0 0 0 281953 0 0 0 197105 0 0 154303 0 0 183800 0 0 1024744 0 1457562 0 0 0 0 0 0 0 0 0 837740 803272 1033040 0 0 0 0 961473 0 0 0 0 0 1044669 0 0 0 1138939 0 0 1469635 1114296 0 771037 912800 1259046 0 0 191911 0 0 0 0 0 0 0 0 0 0 251897 106712 0 0 0 0 0 0 0 0 0 0 110621 0 0 0 0 0 0 234723 95540 0 151439 330176 0 0 0 330246 0 0 0 0 0 0 0 0 0 277187 0 322891 0 0 0 0 457967 0 0 0 0 0 483642 0 0 0 332867 0 0 580333 0 0 269323 367127 604830 -AAIGEGLQAFC(Carbamidomethyl)IPGSVADQR MGYG000000205_02543;MGYG000000038_01050;MGYG000000127_05084;MGYG000001496_01287;MGYG000004762_01356;MGYG000002528_00119 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.87 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 418014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1078892 0 0 0 340711 0 0 0 0 0 0 0 0 0 0 0 0 0 804175 0 999944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIGEGLQAFC(Carbamidomethyl)IPGSVADTR MGYG000001338_01296 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,27IIP@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 S 1.0 GGGtGRT protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIGIPED(Methyl[D](Asp->Glu)ELR MGYG000000236_00428 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10151717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIGIPEE(Glu->Trp)ELR MGYG000000196_04526;MGYG000000029_01860;MGYG000001345_00467;MGYG000003367_00149;MGYG000000044_01913;MGYG000002033_00099;MGYG000002478_01776;MGYG000002905_01187;MGYG000000243_02506;MGYG000001306_00718;MGYG000003221_00520;MGYG000002455_03337;MGYG000000174_01424;MGYG000000355_00809;MGYG000004797_01374;MGYG000000273_02673;MGYG000002575_01735 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.5294117647058824 976|Bacteroidetes 1.0 G 0.6470588235294118 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.5294117647058824 fba 0.6470588235294118 - 1.0 4.1.2.13 0.6470588235294118 ko:K01624 0.6470588235294118 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6470588235294118 M00001,M00003,M00165,M00167,M00344,M00345 0.6470588235294118 R01068,R01070,R01829,R02568 0.6470588235294118 RC00438,RC00439,RC00603,RC00604 0.6470588235294118 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6470588235294118 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6470588235294118 0.6470588235294118 0.6470588235294118 0.6470588235294118 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.6470588235294118 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 991249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIGIPEEE(Glu->Trp)LR MGYG000000196_04526;MGYG000000029_01860;MGYG000001345_00467;MGYG000003367_00149;MGYG000000044_01913;MGYG000002033_00099;MGYG000002478_01776;MGYG000002905_01187;MGYG000000243_02506;MGYG000001306_00718;MGYG000003221_00520;MGYG000002455_03337;MGYG000000174_01424;MGYG000000355_00809;MGYG000004797_01374;MGYG000000273_02673;MGYG000002575_01735 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.5294117647058824 976|Bacteroidetes 1.0 G 0.6470588235294118 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.5294117647058824 fba 0.6470588235294118 - 1.0 4.1.2.13 0.6470588235294118 ko:K01624 0.6470588235294118 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6470588235294118 M00001,M00003,M00165,M00167,M00344,M00345 0.6470588235294118 R01068,R01070,R01829,R02568 0.6470588235294118 RC00438,RC00439,RC00603,RC00604 0.6470588235294118 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6470588235294118 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6470588235294118 0.6470588235294118 0.6470588235294118 0.6470588235294118 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.6470588235294118 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 791491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 837474 0 0 0 0 1298441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2805972 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIGIPEEELR MGYG000000196_04526;MGYG000000029_01860;MGYG000001345_00467;MGYG000003367_00149;MGYG000000044_01913;MGYG000002033_00099;MGYG000002478_01776;MGYG000002905_01187;MGYG000000243_02506;MGYG000001306_00718;MGYG000003221_00520;MGYG000002455_03337;MGYG000000174_01424;MGYG000000355_00809;MGYG000004797_01374;MGYG000000273_02673;MGYG000002575_01735 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.5294117647058824 976|Bacteroidetes 1.0 G 0.6470588235294118 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.5294117647058824 fba 0.6470588235294118 - 1.0 4.1.2.13 0.6470588235294118 ko:K01624 0.6470588235294118 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6470588235294118 M00001,M00003,M00165,M00167,M00344,M00345 0.6470588235294118 R01068,R01070,R01829,R02568 0.6470588235294118 RC00438,RC00439,RC00603,RC00604 0.6470588235294118 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6470588235294118 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6470588235294118 0.6470588235294118 0.6470588235294118 0.6470588235294118 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.6470588235294118 none 1.0 34388024 34725544 49014167 38569614 45598824 32382409 53843573 37669908 37180862 37146433 49804889 36980217 49573300 33975176 32809976 47706991 37503381 23705857 37880750 30055976 36696840 27466928 40490373 44855873 28684924 36573885 40034651 25411965 37122020 41034142 50844753 36581833 58669911 35516132 34044401 44555610 34831619 56386987 24097021 0 23624401 25244920 33173642 26356959 28487766 24669348 24907236 0 39295871 22920670 48010196 29258304 30090422 42386666 22693057 19307565 25893974 23152860 25825220 24437918 23043843 0 25743943 0 25000108 19974201 26014219 29204569 21210163 26446141 26011783 22522193 0 0 25932518 26015686 20059273 15257707 23560492 17382901 29932888 23167954 25631020 15966698 24681921 20527388 23435693 22128664 32441892 20958696 18384023 24116841 20693150 34275247 17115500 16799487 16394504 16185540 27890195 26469702 19211714 19923045 18902468 25416945 19262120 13301602 25878545 15862759 17278334 11553288 21492235 22963565 19746820 23840845 11076115 9915399 11370638 9502724 11715430 10469905 12771828 11451808 10256412 13547306 16115225 11579167 17570320 10786506 9964537 12434063 11688933 10480432 10825416 8269985 0 0 16932049 9241671 10879302 11092414 12588518 8246344 12085484 11463751 10306325 12205683 11670937 10608308 12602363 14223020 0 0 17778186 13469038 15822960 20504558 32274483 25473786 19638892 21483956 20915914 15301499 18600815 15665895 32602006 13270807 15713446 20894819 18386051 39510965 16856770 23254611 11163467 21624392 33322249 21416641 18502911 18160473 13841807 31529742 20513285 22335724 19923068 17571647 10178417 22435811 20210642 15257126 20044277 17882865 -AAIGIPEEELRK MGYG000000196_04526;MGYG000000029_01860;MGYG000001345_00467;MGYG000003367_00149;MGYG000000044_01913;MGYG000002033_00099;MGYG000002478_01776;MGYG000002905_01187;MGYG000000243_02506;MGYG000001306_00718;MGYG000003221_00520;MGYG000002455_03337;MGYG000000174_01424;MGYG000000355_00809;MGYG000004797_01374;MGYG000000273_02673;MGYG000002575_01735 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.5294117647058824 976|Bacteroidetes 1.0 G 0.6470588235294118 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.5294117647058824 fba 0.6470588235294118 - 1.0 4.1.2.13 0.6470588235294118 ko:K01624 0.6470588235294118 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6470588235294118 M00001,M00003,M00165,M00167,M00344,M00345 0.6470588235294118 R01068,R01070,R01829,R02568 0.6470588235294118 RC00438,RC00439,RC00603,RC00604 0.6470588235294118 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6470588235294118 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6470588235294118 0.6470588235294118 0.6470588235294118 0.6470588235294118 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.6470588235294118 none 1.0 12115702 13302971 20789001 13247603 17221267 12075447 15976157 12205399 14380607 11025366 14960839 11030048 20483675 11480271 10570169 17328056 12795688 8075079 15126546 11734439 12431250 10044695 13310764 15567613 9535392 12198246 12499115 10701797 12069004 13368433 17358624 13305539 23845399 11879844 12382059 14376662 11736799 21591169 7471576 5723952 8489950 8479023 9774648 7453482 6846626 8633711 8274324 8015166 12263756 7151731 18910917 8210415 8995507 12631494 7254944 4073625 7366955 7013218 7605915 10035913 5695362 6607450 7794583 7284351 7905233 5318494 7099181 9031454 5416331 7077788 9591459 7713746 8349731 7693097 7972184 8860192 6374139 6169323 8840458 6604992 10439560 8915851 9037084 6049204 8915306 5922831 8610862 8187095 13752325 7027317 6430291 10311495 7018526 12893166 9309268 6840904 5429581 6197694 12093473 9695286 7487420 5787215 6640538 9637407 7287831 5735364 9742496 6012234 6351701 4454429 7192746 8046186 6959292 9483871 3990247 3695401 4250064 3324109 5154625 4302426 3945294 3957204 3845246 4609910 5938052 4295352 6035032 3723861 5209122 5123687 3450332 3961752 4963406 2845523 4036788 0 6955519 3386628 3843749 4150889 3664183 3202149 3873846 3905225 3594803 4876619 3981103 4455260 5269953 4941564 4398197 3892043 6086806 4310039 4593667 5222144 11027809 8632595 6585445 7072027 8040102 4002383 4849680 5236769 9875293 4266178 5728872 7068391 6019052 10057725 5188805 6825365 3678157 7569442 7847753 11744082 5484000 5651429 5061817 8348750 6306862 6924297 5215796 5094414 3130239 7916424 6698337 5005373 6454383 6216499 -AAIGIPEEQ(Gln->Trp)LR MGYG000001346_02842 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 988225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIGIPEEW(Trp->Glu)LR MGYG000002438_02632;MGYG000000138_02337 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16137715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIGIPEEWLR MGYG000002438_02632;MGYG000000138_02337 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 1229396 0 149091 0 0 0 196392 0 198785 256845 156884 0 0 0 0 0 404847 0 0 0 0 164466 150755 157212 0 223085 327889 0 119667 0 92114 385830 0 0 104343 0 0 1637677 1532749 1545031 1632928 2333714 1679725 1538999 2515728 1274450 2913889 2140365 4892749 1713520 2071807 1874122 3015797 2078265 552849 2100667 2210076 9736640 1765165 835651 1527167 2039093 1826028 2236920 773831 2250566 4799923 1064975 3438315 1615982 1304680 1852801 1396711 1500254 1449161 767411 873397 1030478 659645 1711528 1058785 0 474314 1050489 897813 0 2239541 875039 820879 815923 0 859211 1260728 163814 694739 2816308 718458 905312 1055894 825343 726138 724503 846858 955099 1963271 998895 1387519 654589 370292 691624 1084996 887816 0 1038564 1238288 986389 529768 0 726597 819909 694810 728341 1015090 741967 2558901 1292187 727409 751558 1037753 864038 335396 861528 731482 8233542 634683 236533 819837 764861 971776 954231 353312 873840 3051493 792370 1950193 836563 831581 833449 976624 737615 705232 2688613 3790643 2732580 3759120 6319137 3403569 2525797 3352752 3253682 4669099 3422541 9273618 5170440 3064450 2045070 4640591 3256347 3448261 2699121 3205839 9635400 9141022 3229156 4554903 0 3137425 4421459 8101870 4686115 10487755 4260258 22423909 1811038 11096003 28038910 5210970 8507840 7602073 -AAIGITNQR MGYG000000164_01754;MGYG000002274_01022;MGYG000000271_02110;MGYG000001338_01881;MGYG000000038_01493;MGYG000002517_00523;MGYG000000198_04024;MGYG000000142_00490 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 0.375 186801|Clostridia 1.0 C 0.5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1605702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 533285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733679 0 0 0 0 0 0 0 0 0 0 0 -AAIGLAGNNR MGYG000004876_00851 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__|m__MGYG000004876 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4AWF7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1045862 0 0 0 0 791701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524190 0 0 0 0 850312 0 0 0 0 1157201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 606140 0 0 0 0 733154 0 0 0 0 548837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299062 0 0 0 0 1245123 0 0 0 0 1130860 0 0 0 0 0 0 0 0 0 0 -AAIGNYTR MGYG000001313_00488 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,2FMB9@200643|Bacteroidia,4AM6Q@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Oxidoreductase, short chain dehydrogenase reductase family protein 1.0 uxuB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739116 0 0 0 0 594905 0 0 0 0 639228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550091 0 0 0 0 331938 0 0 0 0 337936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3122674 0 0 0 0 2668837 0 0 0 0 2248641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220279 0 0 0 0 174484 0 0 0 0 157636 0 0 0 0 0 0 0 0 0 0 -AAIGQINR MGYG000000404_01456 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA11774|s__UBA11774 sp003507655|m__MGYG000000404 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,25XFI@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 1620559 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1445927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIGTVIGC(Carbamidomethyl)FQDSK MGYG000000187_01839;MGYG000000078_00947 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira 1.0 COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,248C0@186801|Clostridia,25VW8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Glucuronate isomerase 1.0 uxaC 1.0 - 1.0 5.3.1.12 1.0 ko:K01812 1.0 ko00040,ko01100,map00040,map01100 1.0 M00061,M00631 1.0 R01482,R01983 1.0 RC00376 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 LacI,UxaC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucuronate isomerase. uronic isomerase. Also converts D-galacturonate to D-tagaturonate. D-glucuronate = D-fructuronate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1165486 0 0 2162877 0 0 0 0 1512952 0 0 0 0 2121331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 601281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 387387 0 0 0 0 0 0 0 313488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIHEGDTGSPEVQVALLTAR MGYG000001627_01218;MGYG000004732_00360;MGYG000002059_00069;MGYG000003921_01153;MGYG000004866_00975;MGYG000000084_01969;MGYG000001157_00220;MGYG000003937_00355 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3WK6U@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 - 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 447784 0 0 0 588628 0 0 0 504854 0 0 716516 725113 0 0 0 0 1348548 448938 0 0 0 985768 0 668852 472464 0 1296517 656438 0 0 0 0 0 0 0 384122 0 0 0 0 0 305270 0 0 0 0 0 0 1035884 330588 0 0 0 0 550350 0 0 0 0 586762 0 0 0 0 463678 0 0 0 0 0 0 0 0 269605 0 0 0 0 0 0 0 0 0 0 0 0 613672 0 0 0 0 0 493102 0 0 0 0 321594 0 0 0 0 415424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 628445 0 0 0 0 0 657613 0 0 0 0 862452 0 0 0 0 460054 0 0 0 0 0 0 0 0 0 0 543160 0 0 0 361806 0 0 0 400794 0 0 1934922 519469 0 0 0 0 1195701 303119 0 0 0 1021759 0 334177 158692 0 1329776 387845 0 0 0 0 0 0 0 325154 0 -AAIHFVDPEDLGMK MGYG000002163_00221 genome d__Archaea|p__Methanobacteriota|c__Methanobacteria|o__Methanobacteriales|f__Methanobacteriaceae|g__Methanobrevibacter_A|s__Methanobrevibacter_A smithii|m__MGYG000002163 1.0 COG4007@1|root,arCOG03196@2157|Archaea,2XTKJ@28890|Euryarchaeota,23PHM@183925|Methanobacteria 1.0 183925|Methanobacteria 1.0 C 1.0 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT 1.0 hmd 1.0 - 1.0 1.12.98.2 1.0 ko:K13942 1.0 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 1.0 M00567 1.0 R04455 1.0 RC00202 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HMD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 5,10-methenyltetrahydromethanopterin hydrogenase. nonmetal hydrogenase. Does not catalyze the reduction of artificial dyes.-!-Does not by itself catalyze a H2/H(+) exchange reaction.-!-Does not contain nickel or iron-sulfur clusters.-!-Formerly EC 1.12.99.4. 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 = 5,10- methylenetetrahydromethanopterin + H(+). 1.0 1.0 1.0 1.0 Metabolic pathways;Methane metabolism;Carbon metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 880216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIIAEYGR MGYG000000233_02689;MGYG000000205_00957 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,220GG@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 - 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1530115 0 0 1321174 0 0 0 1639395 0 0 0 1185467 0 0 0 0 0 780121 1517446 0 0 0 505967 0 0 1312265 0 641619 0 1171513 0 0 0 1777091 0 0 1518292 0 738626 0 0 1145486 0 0 0 1398720 0 0 0 3862532 0 0 0 0 0 406647 1091932 0 0 0 1063824 0 0 1041105 0 599319 0 2847846 0 0 0 1162441 0 0 987132 0 1070096 0 0 0 0 0 0 644659 0 0 0 473770 0 0 0 0 0 9478326 490190 0 0 0 791507 0 0 446195 0 790396 0 619961 0 0 0 376804 0 0 602982 0 831571 0 0 1000089 0 0 0 420248 0 0 0 837811 0 0 0 0 0 3325723 607595 0 0 0 313338 0 0 309313 0 2212041 0 355118 0 0 0 410387 0 0 845834 0 1422872 0 0 2056659 0 0 0 551363 0 0 0 222627 0 0 0 0 0 303654 1592007 0 0 0 637848 0 0 217562 0 1583275 0 305920 0 0 0 694854 0 0 1455301 0 -AAIIAEYGRK MGYG000000233_02689;MGYG000000205_00957 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,220GG@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 - 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6972538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIIALK MGYG000003697_01278;MGYG000002960_02182;MGYG000003535_00725 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 108967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82814 0 0 0 0 82067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1567700 0 0 0 0 1557705 0 0 0 0 919491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIIEQYGR MGYG000002445_01948 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp003024715|m__MGYG000002445 1.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,220GG@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 - 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIIGGC(Carbamidomethyl)AGTSC(Carbamidomethyl)VLTGK MGYG000001338_03122 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,3WGKF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP 1.0 pncB 1.0 - 1.0 6.3.4.21 1.0 ko:K00763 1.0 ko00760,ko01100,map00760,map01100 1.0 - 1.0 R01724 1.0 RC00033 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 NAPRTase,QRPTase_C,QRPTase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 nicotinate phosphoribosyltransferase. nicotinic acid phosphoribosyltransferase. The enzyme, which is involved in pyridine nucleotide recycling, can form beta-nicotinate D-ribonucleotide and diphosphate from nicotinate and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) in the absence of ATP.-!-However, when ATP is available the enzyme is phosphorylated resulting in a much lower Km for nicotinate.-!-The phospho-enzyme is hydrolyzed during the transferase reaction, regenerating the low affinity form.-!-The presence of ATP shifts the products/substrates equilibrium from 0.67 to 1100.-!-Formerly EC 2.4.2.11. 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate = ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Nicotinate and nicotinamide metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354650 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIIGGGNVAMDAAR MGYG000002884_00905 genome d__Bacteria|p__Cyanobacteria|c__Vampirovibrionia|o__Gastranaerophilales|f__Gastranaerophilaceae|g__UMGS951|s__UMGS951 sp900547155|m__MGYG000002884 1.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 'glutamate synthase 1.0 gltA 1.0 - 1.0 1.4.1.13,1.4.1.14 1.0 ko:K00266 1.0 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 1.0 - 1.0 R00093,R00114,R00248 1.0 RC00006,RC00010,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,NAD_binding_8,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate synthase (NADPH). | glutamate synthase (NADH). NADPH-glutamate synthase. | NADH-glutamate synthase. The reaction takes place in the opposite direction.-!-The protein is composed of two subunits, alpha and beta.-!-The alpha subunit is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.4).-!-The beta subunit transfers electrons from the cosubstrate.-!-The NH3 is channeled through a 31 A channel in the active protein.-!-In the absence of the beta subunit, coupling between the two domains of the alpha subunit is compromised and some ammonium can be produced.-!-In the intact alphabeta complex, ammonia production only takes place as part of the overall reaction.-!-Formerly EC 2.6.1.53. | A flavoprotein (FMN).-!-The reaction takes place in the direction of L-glutamate production.-!-The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2). 2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH. | 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH. 1.0 1.0 1.0 1.0 Nitrogen metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1075381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIIGLTK MGYG000002535_01106;MGYG000002494_03981;MGYG000003372_03990 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria,3XMSX@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 1.0 IQ 1.0 oxidoreductase activity 0.6666666666666666 ucpA 1.0 - 1.0 1.1.1.100 1.0 ko:K00059,ko:K18335 1.0 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 1.0 M00083,M00572 1.0 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R10690,R11671 1.0 RC00029,RC00089,RC00117 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-oxoacyl-[acyl-carrier-protein] reductase. - Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates. a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH. 1.0 1.0 1.0 1.0 Biotin metabolism;Fatty acid metabolism;Fatty acid biosynthesis;Biosynthesis of unsaturated fatty acids;Metabolic pathways;Fructose and mannose metabolism;Prodigiosin biosynthesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4895830 0 0 0 1454428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498615 0 357767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIIGSPTR MGYG000002528_02599;MGYG000000028_00892 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,268EK@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 dhaD 1.0 - 1.0 1.1.1.6 1.0 ko:K00005 1.0 ko00561,ko00640,ko01100,map00561,map00640,map01100 1.0 - 1.0 R01034,R10715,R10717 1.0 RC00029,RC00117,RC00670 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol dehydrogenase. NAD-linked glycerol dehydrogenase. Also acts on 1,2-propanediol. glycerol + NAD(+) = dihydroxyacetone + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 553450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5582253 0 1266935 0 0 0 0 3289362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254282 0 188281 0 0 0 0 330634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIIHGLK MGYG000002052_00761 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum|s__|m__MGYG000002052 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2964869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIIIAVK MGYG000001300_02045 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3WG8A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Participates in both transcription termination and antitermination 1.0 nusA 1.0 - 1.0 - 1.0 ko:K02600 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009,ko03021 1.0 - 1.0 - 1.0 - 1.0 KH_5,NusA_N,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545569 0 0 0 0 258775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428525 0 0 0 0 293361 334019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIILDDKAPESTPTVYR MGYG000002477_01443 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_A|s__Citrobacter_A amalonaticus|m__MGYG000002477 1.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3ZJCJ@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 F 1.0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 deoA 1.0 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 1.0 2.4.2.4 1.0 ko:K00758 1.0 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 1.0 - 1.0 R01570,R02484,R08222,R08230 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 1.0 Glycos_trans_3N,Glycos_transf_3,PYNP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thymidine phosphorylase. pyrimidine phosphorylase. In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.-!-Formerly EC 2.4.2.23. phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine. 1.0 1.0 1.0 1.0 Metabolic pathways;Drug metabolism - other enzymes;Bladder cancer;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1099246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIITTPIEK MGYG000000050_00899;MGYG000000806_00539;MGYG000000201_00039;MGYG000000301_01719;MGYG000001338_03041 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,3XYNY@572511|Blautia 0.8 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.87 0.8 cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CobW_C,cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618750 548640 0 0 0 0 290382 -AAIITTPWDSIR MGYG000002517_01323 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 CobW P47K family protein 1.0 cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CobW_C,cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 312499 0 223005 108186 0 0 0 203343 0 0 0 102468 0 179441 0 202436 0 208035 0 0 0 0 0 209448 0 0 0 0 0 0 164624 0 180702 184951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121744 0 0 0 0 0 0 0 0 0 0 0 0 1109676 0 0 982835 421294 212090 681847 1407095 1068160 587557 402725 702418 0 1363686 1087568 537929 804557 0 1051899 1032339 1030208 0 0 0 1219276 1091290 871258 0 0 924083 0 0 200276 1165298 1196165 1048288 1199102 125992 1616643 0 1290636 0 2108471 1883788 1187431 1339703 1637959 1688905 1171807 1152620 0 1391386 1938797 1474931 1674899 0 1990258 1727383 1301116 1113872 0 1256101 2235026 1607630 2191004 0 0 1882370 0 0 874491 2186788 1418691 1451168 1887724 1211404 -AAIITTPWDSIRGEQILK MGYG000002517_01323 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 CobW P47K family protein 1.0 cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CobW_C,cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 204094 0 156064 0 306392 67460 0 0 0 0 254675 205577 158615 77618 0 0 79068 0 0 173308 173387 200747 0 63501 169790 0 0 0 0 105073 0 0 0 0 0 0 130786 0 0 0 0 0 0 0 0 0 166315 0 150660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253142 0 191503 1524803 82371 234314 0 0 435097 0 74553 177349 111539 77798 0 0 64042 0 0 211574 96389 144534 0 0 206442 195251 242669 0 0 154234 107717 0 141050 0 190279 0 282974 134528 543539 0 135514 574274 230528 72403 0 0 658446 0 348393 374535 127986 686194 0 0 302164 0 0 448801 277030 268299 0 0 724383 650725 499164 0 0 524595 229622 0 68701 0 784128 0 660284 330432 246090 0 905170 0 827985 1161848 0 0 967704 0 1014741 593985 1491786 912463 0 0 819762 0 0 467796 212032 0 0 1038939 443804 523365 372711 0 0 496466 1499947 0 923368 0 0 0 4798545 3092038 -AAIKNPR MGYG000001647_00185;MGYG000000022_02788;MGYG000000312_02404;MGYG000000278_00304;MGYG000003899_02226;MGYG000003166_00833;MGYG000002707_01357;MGYG000002545_01217;MGYG000002274_02693;MGYG000004726_03204;MGYG000002105_00879;MGYG000001300_02837;MGYG000001255_00900;MGYG000002953_01784;MGYG000002040_00906 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.6 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.9333333333333333 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 101175 0 0 0 0 0 0 0 0 0 0 0 0 132200 0 431612 197589 0 176135 0 338645 0 0 0 0 377654 0 0 0 0 0 0 0 0 0 0 0 0 158239 0 0 0 0 0 0 0 0 0 0 0 0 309227 0 0 753430 0 85903 0 601102 0 0 0 0 453263 0 0 0 0 0 0 0 0 0 247862 0 0 350308 0 263430 0 233157 0 0 0 0 0 0 0 0 408541 0 0 251282 0 773626 0 266179 0 0 0 0 432349 0 0 0 0 448477 0 0 0 0 175573 0 0 199516 0 99524 0 832504 0 0 0 0 0 0 0 0 215411 0 338774 205576 0 85751 0 80133 0 0 0 0 450076 0 0 0 0 198353 0 0 0 0 256603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211339 0 0 0 0 43496 0 0 0 0 109182 0 0 0 0 0 0 0 0 0 0 -AAILAEEER MGYG000002438_01848 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,22WFC@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Domain of Unknown Function (DUF349) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306067 0 0 0 0 0 0 0 0 0 0 0 0 0 1456283 0 0 0 0 0 0 0 0 669885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1613829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 700179 0 0 0 0 1476755 0 0 0 0 0 0 0 0 1795837 0 0 0 0 0 0 0 0 2146764 0 0 0 0 0 0 0 0 -AAILAEEERVK MGYG000002438_01848 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,22WFC@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Domain of Unknown Function (DUF349) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1634728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1407814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 711149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAILANK MGYG000001338_00669 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia,3XYGM@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 araB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1324425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1867126 0 0 0 0 1001289 0 0 1582537 0 0 0 0 0 0 0 -AAILDR MGYG000001346_01624;MGYG000004876_03444;MGYG000002549_04587 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAILLDTK MGYG000002494_00983 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,3XMTB@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Pyruvate kinase 1.0 pykF 1.0 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 2.7.1.40 1.0 ko:K00873 1.0 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050 1.0 R00200,R00430,R01138,R01858,R02320 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iECO103_1326.ECO103_1819,iPC815.YPO2393 1.0 PK,PK_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate kinase. phosphoenol transphosphorylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Microbial metabolism in diverse environments;Type II diabetes mellitus;Carbon metabolism;Central carbon metabolism in cancer;Metabolic pathways;Viral carcinogenesis;Glycolysis / Gluconeogenesis;Glucagon signaling pathway;Human papillomavirus infection;Purine metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAILLDTKGPEIR MGYG000002494_00983 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,3XMTB@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Pyruvate kinase 1.0 pykF 1.0 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 2.7.1.40 1.0 ko:K00873 1.0 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050 1.0 R00200,R00430,R01138,R01858,R02320 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iECO103_1326.ECO103_1819,iPC815.YPO2393 1.0 PK,PK_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate kinase. phosphoenol transphosphorylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Microbial metabolism in diverse environments;Type II diabetes mellitus;Carbon metabolism;Central carbon metabolism in cancer;Metabolic pathways;Viral carcinogenesis;Glycolysis / Gluconeogenesis;Glucagon signaling pathway;Human papillomavirus infection;Purine metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1012633 0 0 0 0 0 0 0 0 0 1368245 0 0 0 0 0 1139651 0 0 0 0 0 1056993 0 0 0 0 0 0 0 1384730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 240909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAILPK MGYG000002494_02542 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,1RPCQ@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 C 1.0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases 1.0 qor 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003960,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016651,GO:0016655,GO:0017091,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:1901363 1.0 1.6.5.5 1.0 ko:K00344 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N,ADH_zinc_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADPH:quinone reductase. zeta-crystallin. Specific for NADPH.-!-Catalyzes the one-electron reduction of certain quinones, with the orthoquinones 1,2-naphthoquinone and 9,10-phenanthrenequinone being the best substrates.-!-Dicoumarol (cf. EC 1.6.5.2) and nitrofurantoin are competitive inhibitors with respect to the quinone substrate.-!-The semiquinone free-radical product may be non-enzymically reduced to the hydroquinone or oxidized back to quinone in the presence of O2.-!-Abundant in the lens of the eye of some mammalian species. 2 a quinone + H(+) + NADPH = 2 a 1,4-benzosemiquinone + NADP(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 213751 173333 211104 0 293313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267099 0 278891 0 0 0 0 205091 0 0 0 102319 0 0 0 0 221589 0 527870 576272 329891 0 662535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 504037 754063 0 662847 0 0 0 0 574593 0 0 0 695894 0 0 0 0 543494 0 204435 110175 219409 0 98756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403135 77183 0 67173 0 0 0 0 77129 0 0 0 0 0 0 0 0 65725 0 0 112019 77570 0 80175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77531 92555 0 242325 0 0 0 0 91129 0 0 0 292722 0 0 0 0 103012 0 98115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 62288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153580 -AAILPLSK MGYG000002794_00630;MGYG000000416_00486;MGYG000001733_00367;MGYG000002926_00944;MGYG000002882_01752;MGYG000004196_01635;MGYG000002720_01072;MGYG000002057_00097;MGYG000002116_00583;MGYG000002715_00885 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales 1.0 COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,2N745@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Anticodon binding domain 1.0 glyQS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 1.0 6.1.1.14 1.0 ko:K01880 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03654 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine--tRNA ligase. glycyl-tRNA synthetase. - ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 511996 0 0 0 874026 902873 855533 790227 474420 0 550981 0 0 504795 765406 0 0 0 0 0 0 0 0 1062573 915511 0 0 659447 0 0 547906 783791 1161198 1352163 1066942 547056 557933 0 263675 0 0 0 340478 0 0 0 0 0 237756 0 0 230503 112153 0 0 0 0 0 0 0 0 424883 0 0 0 369462 0 0 256523 494709 591353 454363 547818 237268 1086233 0 529621 0 0 0 0 0 732618 0 0 0 585355 0 0 718600 967984 0 0 0 0 0 0 0 0 815277 1074960 0 0 0 0 0 0 0 0 0 0 0 248439 0 0 0 0 0 225037 106570 219542 0 0 0 143391 0 0 196440 193094 0 0 0 0 0 0 0 0 291758 0 0 0 0 0 0 190754 226671 0 0 186925 163054 1855763 0 0 0 0 0 1223280 1027061 0 1616118 0 0 375110 0 0 0 1479002 0 0 0 0 0 0 0 0 1058005 1388454 0 0 0 0 0 900199 1128731 832102 0 1091735 1036743 -AAILTR MGYG000004828_01320;MGYG000002485_00846;MGYG000001300_02570 domain d__Bacteria 1.0 COG0240@1|root,COG0240@2|Bacteria,378MQ@32066|Fusobacteria 0.6666666666666666 32066|Fusobacteria 0.6666666666666666 I 1.0 Glycerol-3-phosphate dehydrogenase 1.0 gpsA 1.0 - 1.0 1.1.1.94 1.0 ko:K00057 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00842,R00844 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 NAD_Gly3P_dh_C,NAD_Gly3P_dh_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase [NAD(P)(+)]. L-glycerol-3-phosphate:NAD(P) oxidoreductase. The enzyme from Escherichia coli shows specificity for the B side of NADPH. (1) NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH. (2) NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 310545 0 0 0 358520 0 0 293363 0 604135 0 701274 0 430681 0 0 306015 0 0 0 0 0 0 496016 0 0 0 0 0 0 234194 0 0 329309 608656 427947 1082092 0 899106 0 0 0 962728 0 0 976182 0 652875 0 843202 0 814256 0 0 1232063 0 0 0 0 0 0 848523 0 0 0 0 0 0 1103693 0 0 881533 839556 923987 811208 0 168873 0 0 0 0 0 0 477252 0 158348 0 0 0 490637 0 0 215735 0 0 0 0 0 0 1023166 0 0 0 0 0 0 734795 0 0 0 154817 305992 1148035 0 254130 0 0 0 945848 0 0 943239 0 277957 0 786961 0 771579 0 0 209624 0 0 0 0 0 0 606410 0 0 0 0 0 0 373668 0 0 732838 479021 968667 1110155 0 394287 0 0 0 456715 0 0 1406816 0 346355 0 1621219 0 173087 0 0 671458 0 0 0 0 0 0 1094019 0 0 0 0 0 0 0 0 0 1019285 513926 904137 -AAIMKEYAR MGYG000000216_02226 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp003474435|m__MGYG000000216 1.0 COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4H3DG@909932|Negativicutes 1.0 909932|Negativicutes 1.0 M 1.0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family 1.0 - 1.0 - 1.0 - 1.0 ko:K02474 1.0 ko00520,map00520 1.0 - 1.0 R06894 1.0 RC00291 1.0 ko00000,ko00001,ko01000,ko01005 1.0 - 1.0 - 1.0 - 1.0 UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIMLAQK MGYG000000243_02805 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,2FMY9@200643|Bacteroidia,4AM1G@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine 1.0 hisD 1.0 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.1.1.23 1.0 ko:K00013 1.0 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 1.0 M00026 1.0 R01158,R01163,R03012 1.0 RC00099,RC00242,RC00463 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2,DUF559,Histidinol_dh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 histidinol dehydrogenase. - Also oxidizes L-histidinal.-!-The Neurospora enzyme also catalyzes the reactions of EC 3.5.4.19 and EC 3.6.1.31. H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Biosynthesis of secondary metabolites;Histidine metabolism;Biosynthesis of amino acids 1.0 none 1.0 0 0 1068972 0 0 0 0 0 0 0 0 0 1256022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1046775 0 0 0 0 1122075 0 0 0 0 0 0 0 0 0 0 0 0 808937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131269 0 0 0 0 0 0 0 178690 0 0 0 0 0 0 0 0 0 234179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133516 0 0 0 0 128428 0 0 327873 0 0 0 0 0 0 0 0 0 362539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 404788 0 0 0 0 377081 0 0 0 0 0 0 0 0 0 0 0 0 321169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIN(Deamidated)N(Deamidated)GYDMDIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 734289 0 419280 0 394451 517115 0 0 561428 0 741624 797932 0 541696 955917 0 0 0 0 809264 709401 297772 0 0 915621 554503 679108 0 0 835251 0 0 0 907573 0 530732 443144 0 0 0 0 0 235279 0 0 0 591609 0 346379 0 0 219712 349707 0 0 0 0 222118 334832 0 0 200465 483652 448458 293697 0 0 0 0 0 0 378179 0 0 291415 279356 617111 0 426804 0 0 342287 0 0 605481 0 0 458125 0 448476 539662 0 0 0 0 642633 440554 0 0 0 743744 560549 598656 0 0 838279 0 0 676435 537774 0 453980 495464 551626 3935814 0 0 0 2872654 1366085 0 0 3895476 0 0 2504502 0 5119890 4175370 0 0 0 0 3518479 2735497 0 0 0 4212195 3107105 4496842 0 0 4230193 0 0 0 174992 0 0 5135207 0 1412405 0 2713236 0 718362 1752637 0 0 1909711 0 1839489 2878019 0 2455667 2359786 0 0 0 0 990975 2154692 1307679 0 1997750 2054718 1881329 2220660 0 0 1304109 0 0 1963041 1757299 0 2144161 2108112 1690064 -AAIN(Deamidated)NGYDM(Oxidation)DIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIN(Deamidated)NGYDMDIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAINDPLLTEQIDR MGYG000000243_01926 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG2942@1|root,COG2942@2|Bacteria,4NEFV@976|Bacteroidetes,2FN6V@200643|Bacteroidia,4AM2U@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG COG2942 N-acyl-D-glucosamine 2-epimerase 1.0 - 1.0 - 1.0 5.1.3.8 1.0 ko:K01787 1.0 ko00520,map00520 1.0 - 1.0 R01207 1.0 RC00290 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 GlcNAc_2-epim 1.0 - 1.0 - 1.0 - 1.0 - 1.0 N-acylglucosamine 2-epimerase. N-acetyl-D-glucosamine 2-epimerase. Requires catalytic amounts of ATP. an N-acyl-D-glucosamine = an N-acyl-D-mannosamine. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 1633322 2289965 0 1057787 0 1195821 997443 0 0 0 0 805059 0 0 838255 0 0 0 784651 854709 0 1332929 0 0 844280 0 0 0 1323274 0 1273099 1261841 0 0 0 1236339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 593938 618408 0 586860 0 0 675885 0 0 0 0 572001 0 0 533824 0 0 0 709480 0 0 470955 0 0 482210 0 0 0 528490 0 505756 760047 0 0 0 247545 0 0 0 0 0 0 0 450063 281796 0 0 0 0 270381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAINFAK MGYG000001871_01381;MGYG000000077_00330;MGYG000000077_01903;MGYG000000262_02730 domain d__Bacteria 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 0.5 186801|Clostridia 0.75 H 0.5 Pyruvate formate lyase-like 0.75 - 1.0 - 1.0 2.3.1.54,4.3.99.4 0.75 ko:K00656,ko:K20038 0.75 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 0.75 - 1.0 R00212,R06987 0.75 RC00004,RC01181,RC02742,RC02833 0.75 ko00000,ko00001,ko01000 0.75 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 0.75 - 1.0 - 1.0 - 1.0 - 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 0.75 0.75 0.75 0.75 Pyruvate metabolism;Butanoate metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 0.75 none 1.0 416827 2842177 389415 393366 4779069 2404775 163264 2008870 751282 1982910 1836076 1555774 4087291 1331186 3355351 3247809 1426797 0 2327665 2961529 1497014 3300300 0 604236 2770090 1201173 491692 0 516862 413314 337518 2776427 1008057 1475289 1242808 647686 287399 783343 564800 0 158111 0 157790 74001 1014838 220769 505737 0 0 124397 0 0 301576 0 0 0 1246705 699550 0 0 0 0 130139 469015 0 0 0 0 70774 110603 0 0 684091 588270 458012 0 14119975 8648318 2635601 16580139 1842188 9172105 3214095 8946641 5389165 11228349 4318799 4910885 10141110 12528845 20312584 10153160 6147651 0 13638629 19940157 12007306 14048386 0 7162007 24172973 11989256 17259726 0 2574311 7651907 2736842 6163165 4954668 9596440 9559845 4404952 10872203 2337762 7011134 7976398 4163762 9881670 6343439 11326778 11445056 6061469 5969240 16954722 5692844 3132174 7446249 6984534 5195072 16605022 9797439 0 4142680 13081491 2973800 9586894 0 10162561 4124621 1956828 5828678 0 8427273 5805924 5470071 5523355 6403078 2289628 4892323 3907284 3117455 6283442 90460 321542 344152 111807 215127 198985 335627 128562 195217 477973 105238 109703 0 85999 135921 319383 173203 0 124579 190500 0 265314 0 0 0 208975 0 0 296611 346648 117568 0 0 0 105290 169713 126578 200440 -AAINN(Ammonia-loss)GYDMDIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 492330 0 293555 974805 0 423332 584597 601595 811066 835500 0 0 0 527793 1078815 0 0 0 0 469648 987732 763156 0 0 819630 645766 641373 0 0 337244 0 0 0 0 495222 485908 642139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402181 0 577843 0 0 0 330702 357875 360455 0 0 0 0 338822 350440 0 0 0 0 337426 232164 0 0 0 557626 660851 248466 0 0 724285 0 0 547479 0 380350 242159 672443 680835 1724780 0 748467 2251064 0 739403 1488093 2080797 3343269 1643663 0 0 0 2264590 2595885 0 0 0 0 2654379 1332769 0 0 0 2441275 1677788 1974709 0 0 1921757 0 0 460277 0 2647600 2191128 1975290 740447 1420459 0 1952336 0 0 1439893 2232504 1848322 1672234 2603966 0 0 0 2621926 2720052 0 0 0 0 858312 2176941 1324214 0 2202778 2310447 1839228 2192958 0 0 688748 0 0 2506800 0 1579140 2446607 2303326 1889308 -AAINN(Deamidated)GYDM(Oxidation)DIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 563872 424458 246692 858098 625752 506549 1171641 794133 552661 930859 686370 738795 0 551482 1365214 1283643 1017979 0 888487 677259 669550 958664 0 0 839598 457427 502831 0 308359 664861 0 0 572721 738258 384357 312124 650979 435790 335730 0 0 411168 268601 0 0 0 0 297648 315520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360639 0 0 0 0 0 0 0 349442 372590 0 0 606230 861547 651731 522868 1049869 344111 1134595 727458 566495 621631 381133 579693 0 306151 505458 792747 475566 0 641037 613334 827086 350994 0 1240795 737067 846175 649310 0 804788 807120 0 0 805863 405830 353189 933865 665778 619524 3093781 1579420 1065184 3010977 2346615 1569090 1720754 3329495 0 2136922 1136826 2431307 0 4316890 4144632 1598528 2523147 0 3041130 3370656 2523555 391097 0 768267 3288791 2775031 3470534 0 1674482 3105881 0 0 1791364 1263337 3046866 2323762 3371272 0 1645130 1501742 3205043 245661 564486 1893470 2820650 1430179 2055080 4178604 3171276 3442305 0 4422319 3145173 1289531 2278154 0 2932240 914969 2687878 1152880 0 2202243 3210256 1937662 3057180 0 765959 926603 0 0 3720056 2630537 1782100 2799497 2347494 2188828 -AAINN(Deamidated)GYDMDIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 12175226 8924623 5800238 14005310 8041379 0 5585531 13969727 0 0 11785558 15824299 9097495 8544564 13339035 6819393 0 1785037 0 0 13925593 0 2146370 0 0 0 11023647 2539511 5499616 14576072 465259 3762054 4439616 12458731 10593288 8759023 10539171 3639554 1846190 1122397 1723055 0 851413 1058567 1301291 0 807660 1264626 411207 0 1640147 1587444 1917214 1430840 1156451 7648314 1532776 0 1690474 963000 4548690 0 1832311 644626 0 5536207 1059570 2233244 1117083 1530357 2079489 1835491 921977 1580770 1610407 703515 2482826 3590813 10075007 6038798 1267809 3156133 1871280 2381526 0 2269433 0 0 0 0 2369579 0 4483481 2539606 8554945 7578404 2019494 3609542 3627517 1208488 9657487 10047766 9133142 4864630 1523165 2702028 3934236 4128019 0 2257681 2460788 6577813 0 0 53004488 13911944 0 0 31455464 18418328 26418448 50150012 57113059 0 15422839 30183659 14037650 65747159 58187778 27452811 41035324 1933017 40933449 49280491 29372568 6306044 2284803 6625991 48836410 0 0 483541 14961822 39783890 15119337 17625658 13583104 22419821 39652354 34988385 66243538 13907033 0 0 0 444962 0 0 0 0 0 0 0 49124617 0 43096572 0 26868000 0 245802 0 19140114 0 0 356593 0 0 31842881 0 495891 0 0 0 0 0 29429389 0 0 38548744 27545464 -AAINNGYDM(Oxidation)DIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 821527 613291 318525 1461013 861882 945281 871372 821631 948192 1134177 985447 1350327 850502 830819 1512392 1594869 2405967 0 1007377 985749 1234320 1028229 0 596222 1415366 904351 870316 0 572349 1141472 309771 296137 338986 957834 1050014 767596 847007 416473 0 325753 0 0 321526 178047 0 262737 427920 0 230074 0 0 220918 0 0 309927 0 0 156723 0 279782 0 239062 295660 0 0 0 170033 0 330363 245247 0 244985 0 136567 0 361638 881020 1130639 1390990 1131650 515040 438794 937935 697930 907299 720301 788754 962752 720766 931459 898585 821743 672240 0 800735 782758 756412 333527 0 684672 876259 1073882 898953 0 832744 854196 649774 550969 1104311 751949 660279 1041767 1019928 1415720 0 1209829 1103459 3947613 3127084 1487337 0 4172295 4984453 2506207 1647676 2966272 1258752 4080394 3900628 1794195 3404352 0 3332263 3730601 2695800 272158 0 1267708 3779421 3442984 3117295 0 1412798 3592413 1671362 1986213 1416722 1671317 3863541 2708891 3982859 1222726 2481011 1789882 2772432 161739 755175 2147225 2597210 2073972 2139831 3498064 2868637 2649622 1150307 4263651 2909788 1989314 2478922 0 2482517 1619753 2589770 2112088 0 2611635 3739418 2050640 4027149 0 812936 1123430 1972650 692634 2991953 2339200 2330238 3054631 2589285 2401270 -AAINNGYDMDIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 13418921 8629178 7846564 23011437 12293853 11100809 11960623 14186770 14966853 20371396 16811751 23734780 11723465 11963557 19662039 9232309 13738773 2159332 13448695 13516944 17013699 9562409 2772123 6088464 20706676 12998332 13064108 1999803 7986470 16541430 3457986 3213450 5518042 13128076 10054543 12147547 12781113 7199117 1119763 798588 1491286 1209657 2122322 650564 1205046 672455 929150 950736 1995796 1001773 1564186 984969 692269 1371195 1004514 7207928 657590 1115222 376478 507359 4612492 641511 982523 899872 893458 5743015 775205 1082508 985085 378706 2066424 892229 476357 1010848 747770 1958430 9716765 3631758 9791120 7024126 4235845 2636198 8350058 6880135 8138697 4966322 6645606 9875466 6433751 8517426 9211744 7516251 5633339 2065877 8690725 9172261 6929622 3143813 3642958 2773377 9081406 11711398 7874946 4643010 4916203 11753247 3953241 2398873 10683454 7225662 5918714 7396013 12678368 11295034 43849217 12785734 11977369 57972016 33255002 16589581 31669460 55539622 62909198 30805550 20008824 33114604 14421471 58008429 50034616 21066067 44087741 2118240 47037429 47754255 34538199 5909768 1058618 7248197 49420286 42876210 49697967 2073510 15833102 44467034 16404691 18172198 12515247 18435779 47572651 33180132 45371873 11552346 32364767 36575869 42738939 1876968 13829629 39063655 46273392 33845705 36064974 59729691 34432121 56775006 12408237 55448649 63020991 36823959 56131297 1870687 53252286 22587992 49980040 39719254 2346344 49328662 40973396 31936547 53348306 3474309 10694164 20229098 33732390 11896732 50114657 40733245 31274345 49636824 50144627 34406994 -AAINNGYDMDIK(Lys->Arg) MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 2136928 0 1299459 3393383 1683625 1738053 0 2017390 2173749 3508422 937344 1528782 1549348 1599664 2580105 1080954 2823269 0 2620417 2261758 3296971 1992631 0 976257 2853971 2013012 0 0 0 1865568 0 0 987372 1809069 1947727 1778284 2470968 1059712 621895 0 0 375366 350578 423600 0 321444 395088 502743 343341 156035 427588 474547 0 537617 904285 0 311278 271770 294427 0 0 613764 495733 0 0 0 0 738683 0 0 0 452613 0 276566 0 0 179088 0 338502 336425 0 238754 0 393780 0 0 0 0 0 0 0 399061 0 0 0 0 765409 0 0 285606 394402 0 0 0 0 380085 0 0 0 404819 461837 0 501126 236886 0 0 0 256522 0 385533 0 193837 0 0 0 0 324604 0 0 0 248618 0 0 0 0 0 0 0 466607 353662 0 0 0 0 0 0 267544 0 389518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAINQASDVAALDNVR MGYG000002477_03370;MGYG000002535_02256;MGYG000002534_02305;MGYG000002494_00955 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,3XNIZ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily 1.0 pheS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 1.0 6.1.1.20 1.0 ko:K01889 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iSSON_1240.SSON_1444,iYL1228.KPN_02176 1.0 Phe_tRNA-synt_N,tRNA-synt_2d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 669403 0 0 772845 0 0 0 702928 0 0 0 651056 0 0 696504 0 1007406 0 836248 774014 0 824587 0 0 0 0 1091738 763263 0 0 621587 0 0 0 0 444030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAINQASDVAALDNVRVEYLGK MGYG000002477_03370;MGYG000002535_02256;MGYG000002534_02305;MGYG000002494_00955 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,3XNIZ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily 1.0 pheS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 1.0 6.1.1.20 1.0 ko:K01889 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iSSON_1240.SSON_1444,iYL1228.KPN_02176 1.0 Phe_tRNA-synt_N,tRNA-synt_2d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766896 0 0 850762 0 0 0 0 0 0 0 0 0 0 842835 0 646138 0 0 1180657 0 825731 0 0 0 0 0 0 0 0 514440 0 0 0 0 350891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAINQMELNPNFNAGR MGYG000001410_01243 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__Sutterella wadsworthensis_A|m__MGYG000001410 1.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,2VIYM@28216|Betaproteobacteria 1.0 28216|Betaproteobacteria 1.0 E 1.0 PFAM peptidase T2 asparaginase 2 1.0 iaaA 1.0 - 1.0 3.4.19.5,3.5.1.1 1.0 ko:K01424,ko:K13051 1.0 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 1.0 - 1.0 R00485 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Asparaginase_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 beta-aspartyl-peptidase. | asparaginase. L-asparagine amidohydrolase. Other isopeptide bonds, e.g. gamma-glutamyl and beta-alanyl, are not hydrolyzed.-!-Formerly EC 3.4.13.10. Cleavage of a beta-linked Asp residue from the N-terminus of a polypeptide. | H2O + L-asparagine = L-aspartate + NH4(+). 1.0 1.0 1.0 1.0 Cyanoamino acid metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1004950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1176248 0 0 0 -AAINVGK MGYG000001652_01307 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__V9D3004|s__V9D3004 sp002349525|m__MGYG000001652 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,27J0E@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 PEP-utilising enzyme, TIM barrel domain 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 905293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1361380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372686 0 0 0 0 359237 0 0 350744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAINVK MGYG000000142_02834;MGYG000000463_01481;MGYG000000140_01464;MGYG000000417_00539;MGYG000000031_02405;MGYG000001698_00702;MGYG000000249_01089;MGYG000000398_01662;MGYG000000036_01410;MGYG000001757_01805;MGYG000000728_00587;MGYG000003307_01519;MGYG000001531_01607;MGYG000003581_02331;MGYG000001315_01921;MGYG000000194_03193;MGYG000002963_02777;MGYG000004296_00104;MGYG000000242_00224;MGYG000002945_01502;MGYG000000133_02955;MGYG000000201_02673;MGYG000000196_03104;MGYG000002279_01986;MGYG000004558_03187;MGYG000000251_01169;MGYG000000153_02081;MGYG000004810_00381;MGYG000003821_02000;MGYG000000383_01314;MGYG000000164_00358;MGYG000000159_02392;MGYG000000404_01435;MGYG000002966_02744;MGYG000000187_00493;MGYG000002492_01692;MGYG000004547_00698;MGYG000004845_02015;MGYG000000806_02014;MGYG000000089_02490;MGYG000000243_00081;MGYG000000002_01928;MGYG000001310_01399;MGYG000003432_00750 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.2727272727272727 186801|Clostridia 0.9545454545454546 G 0.9545454545454546 Belongs to the PEP-utilizing enzyme family 0.7045454545454546 ppdK 0.9545454545454546 - 1.0 2.7.9.1 0.9545454545454546 ko:K01006 0.9545454545454546 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.9545454545454546 M00169,M00171,M00172,M00173 0.9545454545454546 R00206 0.9545454545454546 RC00002,RC00015 0.9545454545454546 ko00000,ko00001,ko00002,ko01000 0.9545454545454546 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9545454545454546 - 1.0 - 1.0 - 1.0 GT1 0.9318181818181818 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.9545454545454546 0.9545454545454546 0.9545454545454546 0.9545454545454546 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 0.9545454545454546 none 1.0 4550892 3644932 2970383 0 0 3376167 2651117 3466423 3629126 3937613 6451524 0 7046735 3453603 4782694 5262521 3404603 0 3051121 0 6218367 7134221 6630208 2927793 0 3430161 4300537 0 3358750 2901544 2799897 2892422 3819749 4913974 5685927 3138595 3873859 5253256 3025217 3810703 3239929 3871469 4448048 0 4889534 4627525 2207225 2000835 4223160 3485644 4904925 2207370 2707591 2856936 0 5696033 3092202 4759448 2323913 1469005 4873646 0 3101823 3445394 3737063 11458844 0 2924249 7381579 3283963 4132086 5966352 5736834 5296223 4787829 7715232 3514906 5639931 8861208 4501827 4874310 3220377 3937587 5053487 3518994 7297737 5029705 4182082 5248061 4514436 5880747 7602317 4485200 485227 7190161 0 0 8335873 5786127 6713024 7538373 5365769 5917922 11014010 5126228 4979391 0 10377045 10938764 5877995 5282945 6148725 0 7658344 4773634 0 0 0 0 781697 0 2758546 4060100 1372729 833890 1426257 0 3449123 3223084 0 2147021 1424868 2193001 4043315 1584762 1958109 534136 1568514 0 2320752 2630838 0 0 4172405 2533051 858841 0 1733393 0 2795521 7377664 2835567 0 5063787 0 7510162 3365953 2565046 8323630 4189691 0 0 7495160 0 1611799 0 6525246 2293853 0 2144200 2864955 0 0 4345497 3255472 4598491 7237630 0 9510204 3003058 6674563 3142597 0 675258 0 4795090 6752443 0 0 8442165 -AAINVQK MGYG000001687_00537;MGYG000000271_00388;MGYG000004735_00207;MGYG000004487_00114;MGYG000000145_01088;MGYG000000245_03386;MGYG000001688_03814;MGYG000001619_00896;MGYG000000258_01879;MGYG000002926_01683;MGYG000002143_00035;MGYG000002707_01357;MGYG000003979_01382;MGYG000003074_00103;MGYG000004271_01396;MGYG000000152_05136;MGYG000003504_01005;MGYG000000099_03199;MGYG000002517_01243;MGYG000002025_01833;MGYG000004475_00310;MGYG000002720_01364;MGYG000003013_00135;MGYG000002794_01254;MGYG000000268_00698;MGYG000001496_03326;MGYG000001733_00637;MGYG000000175_01356;MGYG000000076_02377;MGYG000000472_00116;MGYG000001607_01964;MGYG000000387_01345 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.34375 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8125 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 0.96875 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 6403354 0 0 0 0 0 4703509 4131131 5464393 0 4293751 5781688 0 0 0 0 0 5117755 0 0 8968605 4533721 4637458 3483444 0 6352457 6342463 0 3678549 0 1443351 1963045 0 8554917 6861533 5912718 7933211 2099418 1965078 1655805 126974 1916738 0 1201633 1184356 2218634 2393675 1682037 1540330 1304161 1525468 2001659 1678778 1371377 849307 1813057 847937 2385489 1035671 0 2342763 1031213 1721245 2232852 2167407 0 3094534 1090568 1448134 1546756 1824024 2870141 2533420 2617241 2116983 2005229 4919993 0 2602625 5456580 0 3440130 4876314 8110572 7255512 7351398 3294308 4509314 5217989 9034569 8699962 4853320 6685851 0 7475114 0 0 4027586 6050237 3581051 0 9134247 8664249 6280381 7516860 0 0 3725811 4973357 8161628 0 7525412 6043507 0 21663011 3965991 6488831 22525305 0 9398824 8770374 0 16043890 13470059 9758151 11574066 7543457 20136656 30066608 7854163 0 3167980 0 17720810 5160276 0 1087478 5824717 0 13791237 15845268 5018762 6710296 20031141 6055993 5638625 9157681 16584102 0 15366772 28139023 6771167 0 0 0 0 0 17896072 22489572 0 0 0 0 0 8478468 0 0 0 24023964 0 0 0 0 9332225 0 0 29383189 0 0 0 13400003 0 0 0 0 0 19860486 0 30917968 0 -AAINVQKK MGYG000002720_01364;MGYG000000131_01163;MGYG000003013_00135;MGYG000000271_00388;MGYG000002794_01254;MGYG000000245_03386;MGYG000004475_00310;MGYG000001733_00637;MGYG000002143_00035;MGYG000000076_02377;MGYG000002707_01357 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.5454545454545454 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 0.9090909090909091 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 647663 0 0 0 0 0 636136 0 0 0 0 539806 0 0 0 0 0 0 0 381029 593020 0 0 0 454142 386128 697462 0 0 739116 0 0 0 677699 0 598536 606425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241270 0 0 0 0 0 120820 0 0 0 0 108850 0 0 0 0 0 0 0 472397 435376 0 0 0 410402 419708 476298 0 0 105657 0 0 0 373978 0 382845 525508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298735 0 0 0 0 1244656 0 0 0 0 0 0 0 281334 216563 0 0 0 250040 250113 653873 0 0 603999 0 0 0 559467 0 243052 788110 0 -AAIPE(Glu->Gly)LGDNVQFHDLATAAR MGYG000000164_02794 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0191@1|root,COG0191@2|Bacteria,1TRS4@1239|Firmicutes,3VSU5@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 H 1.0 Fructose-bisphosphate aldolase class-II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1060569 0 0 837251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269831 0 0 151466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIPEGAR MGYG000000084_01831 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger formicilis|m__MGYG000000084 1.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3WGWM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Glucose-1-phosphate adenylyltransferase, GlgD subunit 1.0 glgD 1.0 - 1.0 2.7.7.27 1.0 ko:K00975 1.0 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 1.0 M00565 1.0 R00948 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Hexapep,NTP_transferase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-1-phosphate adenylyltransferase. ADP-glucose synthase. - alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Biofilm formation - Escherichia coli;Metabolic pathways;Starch and sucrose metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1330508 0 0 0 0 0 0 0 0 0 1371786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1579387 0 0 0 0 0 1237964 0 0 0 0 1670805 0 0 0 0 1722628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802435 0 0 0 0 0 678599 0 0 0 0 855749 0 0 0 0 611931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1334080 0 0 0 0 0 1540492 0 0 0 0 427053 0 0 0 0 2131147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIPTIK MGYG000000196_04506;MGYG000000301_01011;MGYG000000003_00285;MGYG000000258_00429;MGYG000000170_00153;MGYG000000154_00118;MGYG000000262_01196;MGYG000000074_02205;MGYG000000414_01789;MGYG000000044_00323;MGYG000000142_01978;MGYG000002528_00366;MGYG000002549_02739;MGYG000002438_03839;MGYG000002455_00199;MGYG000002395_00974;MGYG000003279_01634;MGYG000001683_01828;MGYG000001338_02546;MGYG000000271_03251;MGYG000000084_00216;MGYG000003452_00954;MGYG000000133_02282;MGYG000004735_01945;MGYG000004876_02584;MGYG000002098_01090;MGYG000001489_04176 domain d__Bacteria 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,22UY0@171550|Rikenellaceae 0.18518518518518517 976|Bacteroidetes 0.4444444444444444 F 0.5925925925925926 Belongs to the phosphoglycerate kinase family 0.5925925925925926 pgk 1.0 - 0.9259259259259259 2.7.2.3,5.3.1.1 0.5555555555555556 ko:K00927,ko:K01803 0.5555555555555556 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.5555555555555556 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 0.5555555555555556 RC00002,RC00043,RC00423 0.5555555555555556 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 0.5555555555555556 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 0.5555555555555556 0.5555555555555556 0.5555555555555556 0.5555555555555556 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.5555555555555556 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3098155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2428113 0 0 0 0 0 0 2883751 0 0 0 0 0 0 0 0 0 0 0 0 0 3168528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2767537 0 0 0 -AAIPTIR MGYG000001302.1_01773 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,22UY0@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117231 0 0 0 0 181107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94443 0 0 0 0 0 0 0 0 0 134740 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 595508 0 0 0 0 556341 0 0 0 0 352815 0 0 0 0 0 0 0 0 0 0 -AAIQAEIDANNAAVK MGYG000002143_00635 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900545585|m__MGYG000002143 1.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,2N67Z@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Seryl-tRNA synthetase N-terminal domain 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIQELR MGYG000001783_01160 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900551065|m__MGYG000001783 1.0 COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,2FM5N@200643|Bacteroidia,4AKZF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 - 1.0 - 1.0 ko:K03695 1.0 ko04213,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - multiple species 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226557 0 0 0 0 525477 0 0 0 739519 285311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1354397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534333 0 0 0 0 944364 0 0 0 317291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 812699 0 0 0 0 0 0 0 0 924474 0 0 0 0 0 0 0 0 0 0 0 -AAIQIK MGYG000001346_00290 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,2FN9P@200643|Bacteroidia,4AN2N@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 xylA 1.0 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 1.0 5.3.1.5 1.0 ko:K01805 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 - 1.0 R00878,R01432 1.0 RC00376,RC00516 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 xylose isomerase. D-xylose ketol-isomerase. Contains two divalent metal ions, preferably magnesium, located at different metal-binding sites within the active site.-!-The enzyme catalyzes the interconversion of aldose and ketose sugars with broad substrate specificity.-!-The enzyme binds the closed form of its sugar substrate (in the case of xylose and glucose, only the alpha anomer) and catalyzes ring opening to generate a form of open-chain conformation that is coordinated to one of the metal sites.-!-Isomerization proceeds via a hydride-shift mechanism. alpha-D-xylose = alpha-D-xylulofuranose. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIRIPFFER MGYG000000271_00922;MGYG000004271_01649 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,247MK@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 SPFH Band 7 PHB domain protein 1.0 - 1.0 - 1.0 - 1.0 ko:K07192 1.0 ko04910,map04910 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03036,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Band_7,Flot 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Insulin signaling pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIRPFVLDANEQAGANFA(Ala->Pro)TLK MGYG000001306_03824 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 817778 0 0 0 0 1186484 0 0 0 0 856509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAISAG(Gly->Xle)LK MGYG000002506_02514 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,3XMZG@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 scpA 1.0 GO:0003674,GO:0003824,GO:0004494,GO:0005488,GO:0008144,GO:0016853,GO:0016866,GO:0019842,GO:0031419,GO:0036094,GO:0046906,GO:0048037,GO:0097159,GO:1901363 1.0 5.4.99.2 1.0 ko:K01847,ko:K01848 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECO111_1330.ECO111_3653,iECO26_1355.ECO26_4004 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAISEINK MGYG000000164_02895 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,27PVR@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 5088363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4175749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1468311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1610458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1718933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 955965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1594096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1180460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732783 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAISLAK MGYG000001378_03520;MGYG000001345_01966 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,2FMY9@200643|Bacteroidia,4AM1G@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine 1.0 hisD 1.0 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.1.1.23 1.0 ko:K00013 1.0 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 1.0 M00026 1.0 R01158,R01163,R03012 1.0 RC00099,RC00242,RC00463 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2,DUF559,Histidinol_dh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 histidinol dehydrogenase. - Also oxidizes L-histidinal.-!-The Neurospora enzyme also catalyzes the reactions of EC 3.5.4.19 and EC 3.6.1.31. H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Biosynthesis of secondary metabolites;Histidine metabolism;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 553969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAISLDDKAPEITPTVYR MGYG000002494_02884 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3ZJCJ@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 F 1.0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 deoA 1.0 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 1.0 2.4.2.4 1.0 ko:K00758 1.0 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 1.0 - 1.0 R01570,R02484,R08222,R08230 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 1.0 Glycos_trans_3N,Glycos_transf_3,PYNP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thymidine phosphorylase. pyrimidine phosphorylase. In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.-!-Formerly EC 2.4.2.23. phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine. 1.0 1.0 1.0 1.0 Metabolic pathways;Drug metabolism - other enzymes;Bladder cancer;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 561199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1156176 0 770473 0 0 0 0 0 0 0 0 626593 0 0 0 0 424708 0 0 0 0 0 193032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260405 0 0 0 0 0 0 0 0 121574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAISLDN(Deamidated)KAPEITPTVYR MGYG000003372_04094 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter|s__Citrobacter werkmanii|m__MGYG000003372 1.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3ZJCJ@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 F 1.0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 deoA 1.0 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 1.0 2.4.2.4 1.0 ko:K00758 1.0 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 1.0 - 1.0 R01570,R02484,R08222,R08230 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 1.0 Glycos_trans_3N,Glycos_transf_3,PYNP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thymidine phosphorylase. pyrimidine phosphorylase. In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.-!-Formerly EC 2.4.2.23. phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine. 1.0 1.0 1.0 1.0 Metabolic pathways;Drug metabolism - other enzymes;Bladder cancer;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1173856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAISSPLLETSIAGAR MGYG000003937_01659;MGYG000000573_01385;MGYG000003921_01788;MGYG000004700_01055;MGYG000001157_02513;MGYG000004732_00963;MGYG000001627_00389 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 0.8571428571428571 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 911473 0 729203 0 0 0 0 0 645838 0 1055758 0 0 0 0 582396 0 0 0 0 1227446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822840 0 0 0 0 708781 0 0 0 0 757526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290451 0 0 0 0 0 192146 0 657426 0 0 0 0 420271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351912 0 279403 0 0 0 0 0 244103 0 1678036 0 0 0 0 1751044 0 0 0 0 1797461 0 0 0 0 0 0 0 0 0 0 -AAITAALIK MGYG000002395_00912;MGYG000003683_00404;MGYG000000756_00589;MGYG000003452_00999;MGYG000001490_01038;MGYG000002469_01207;MGYG000001292_01083 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CYVQ@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,Ribosomal_S2,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 308774 332071 1049848 0 0 405490 0 0 0 608506 0 350807 1377571 315214 747543 1194106 0 281721 456460 564024 384024 367644 190918 0 534507 271226 236059 230833 387730 228153 0 157544 729641 314035 299436 0 138239 825357 1809913 1628297 2139394 0 0 2759272 0 0 0 1757660 0 901896 6660718 1228165 1448722 2939058 0 8159039 1093320 1808707 1014046 1591701 2777068 4854726 1500418 1281091 1682923 5021971 2303087 1298399 0 875317 1911690 2163053 2113434 0 1580785 3134079 1619190 1316454 1011093 0 0 489464 0 0 0 1231561 0 819727 917478 906779 1442482 1914845 0 409474 1234371 1711902 1158514 1254256 737384 414301 1304502 997725 1534156 1256331 964948 1312076 0 1155137 2215562 1492500 1727646 0 1016129 974237 380329 325437 267245 0 0 952892 0 0 0 319984 0 109194 494604 278454 519658 1023373 0 0 163077 423115 161483 1210205 2458443 1068031 553336 566788 278111 956420 577891 240571 0 653485 342928 817267 663160 0 292904 428331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAITAEVR MGYG000002506_02942;MGYG000002494_02450;MGYG000002323_00405 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,3XPK7@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 574495 0 0 0 534165 0 0 0 0 0 0 0 0 521050 0 0 525102 0 0 0 0 0 0 0 0 0 0 0 350924 0 0 0 0 0 0 0 0 0 1305874 728756 0 0 1277552 0 0 0 0 0 0 0 0 868650 0 0 1896798 0 1389975 0 0 0 0 0 0 0 0 0 860089 0 0 0 0 0 0 0 0 0 1699785 1283331 0 0 1508417 0 0 0 0 0 0 0 0 1236177 0 0 1408852 0 1611896 0 0 0 0 0 0 0 0 0 1416499 0 0 0 0 0 0 0 0 0 902569 1374620 0 0 1791178 0 0 0 0 0 0 0 0 1743952 0 0 615290 0 514582 0 0 0 0 0 0 0 0 0 964825 0 0 0 0 0 0 0 0 0 0 374474 0 0 590078 0 0 0 0 0 0 0 0 455257 0 0 335072 0 394642 0 0 0 0 0 0 0 0 0 498724 0 0 0 0 -AAITAVLAAR MGYG000002492_00344 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 970061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 854364 0 0 0 0 872017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAITDAR MGYG000001313_00702;MGYG000001661_00104 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG3746@1|root,COG3746@2|Bacteria,4NK1Y@976|Bacteroidetes,2FKYR@200643|Bacteroidia,4AW00@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 ko:K07221 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.5.1 1.0 - 1.0 - 1.0 Porin_O_P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4866930 2363994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAITHPVLSGPAYER MGYG000000074_02321;MGYG000002082_01295 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 F 1.0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 357240 0 0 0 127557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366350 0 0 0 0 0 482777 0 0 0 298518 0 0 0 0 0 0 151682 0 308137 0 0 0 405696 0 0 0 0 0 0 0 0 0 0 0 0 0 410149 672653 0 0 0 0 0 534304 0 0 0 0 0 0 0 0 0 0 411326 0 498343 0 0 0 371505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 404562 0 0 0 0 0 535909 0 0 0 643472 0 0 0 0 0 0 313206 0 183536 0 0 0 498291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 404176 0 0 0 0 0 0 0 0 1381804 0 0 0 1874248 0 0 0 0 0 0 0 0 0 0 0 0 0 1931862 2809922 0 0 0 0 0 1231609 0 0 0 1539191 0 0 0 0 0 0 1423921 0 -AAITIPAK MGYG000002281_03589;MGYG000000196_01829 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia,4ARQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2130842 2088596 1396575 2098456 1920958 1886527 2176429 1855910 1845172 2063433 1057628 1787015 1199310 2180882 1736726 1795134 2003064 640693 1668179 2016044 2269399 1246870 1109191 2353082 1553027 1953893 1943195 636347 3310275 1108799 2018207 2744506 1802194 2454598 2374773 1892668 2394386 1728983 2914708 2253653 2505890 2549416 2182056 0 2234628 2750553 2622906 2724538 2300394 0 1956161 2563502 0 2248113 2391904 0 2017488 2058668 2210055 2456685 390077 1708896 2357187 2308233 2416818 267464 2138790 2034858 1379603 2017061 2800249 3163738 2663366 2491176 2424459 0 732106 805815 820120 1040821 938256 949877 1234438 954137 1172422 681822 994985 612060 735997 1204477 1037080 774278 775152 1090888 707265 812094 734316 754717 942390 1112280 867201 836936 787112 294840 1057146 787326 1002598 703363 610046 937244 508737 1099943 956954 0 647986 142353 193078 982079 190705 333621 721220 747758 283075 173677 340503 566628 577088 148890 771865 193742 0 183552 835023 1026193 861658 430397 444897 271516 846220 794831 582372 455618 179262 188740 156169 902010 147069 1570247 683360 988068 840713 324147 1833769 1127536 1267784 2634503 1873271 1836013 2059396 2354583 2440902 2041918 1039797 1595875 1289643 1359402 1566682 999752 2085808 470570 1347760 2442237 1301780 1389319 380988 1484110 0 2978095 1408758 283975 2084281 2084196 0 1449617 783072 2573566 0 1342540 1944420 1477856 -AAITIPAKK MGYG000002281_03589;MGYG000000196_01829 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia,4ARQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1461436 1568906 791070 1294274 1034049 1414951 1460970 997198 1012608 969715 497789 859675 997713 1583893 660475 1219424 1170002 0 895009 1443106 1349742 1177503 0 999321 801888 905023 1015108 0 1625874 848845 1050226 1852844 1189258 1809881 1168163 1030518 1610284 1341100 1849653 1564101 1914506 1359441 1196119 843366 888197 1105397 1517220 1517710 1241513 1142280 983535 1283968 951753 863523 1334955 0 671827 800149 868193 882437 0 935365 912811 1066949 1126327 0 1214724 868459 956981 1564528 1737957 2094941 874439 1473231 1466665 1292288 288182 488544 446174 436786 554013 505885 624689 205973 646196 315611 562562 191312 303125 410741 343123 469842 241487 0 277291 388185 343413 468126 0 404677 365635 160742 388356 0 581306 320877 591308 267673 252525 423282 125731 543795 496305 501482 408120 387876 185159 201099 320044 300065 528188 536916 433297 455356 306659 428721 60706 317927 358055 388937 269392 0 377170 384442 152909 183057 0 184998 446396 642300 353384 0 447932 179320 274923 525075 315553 588358 463250 490846 471958 221790 880133 678174 0 1685299 927211 1223249 1505886 1618198 1638283 1291536 712713 1056560 1351622 946360 1038012 706813 1081532 0 885264 1298779 1025405 1083353 0 820174 0 1887822 914290 0 786794 1518157 0 908166 0 2112758 1173096 1752577 1368145 988154 -AAITPVVNATV(Val->Xle)DR MGYG000004487_00297 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900547745|m__MGYG000004487 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1766673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2321850 0 0 0 0 0 0 2162254 2007629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAITPVVNATVD(Methyl[D](Asp->Glu)R MGYG000004487_00297 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900547745|m__MGYG000004487 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1537058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1787200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAITPVVNATVER MGYG000002794_00763;MGYG000002143_01959;MGYG000001733_00672;MGYG000004196_01673;MGYG000004475_00752 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 0 0 232014 311519 0 480556 0 539720 342977 0 0 0 0 396481 0 0 604113 0 0 0 0 0 0 189016 387047 0 408007 0 0 0 0 412705 189124 327924 357542 0 0 254480 0 0 0 450135 0 131050 0 206891 0 0 0 0 0 121827 0 0 674176 0 0 0 0 242864 0 469577 0 0 0 0 0 0 0 160724 0 446161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1891961 0 1774606 0 2346905 2017800 0 0 0 0 1667784 0 0 1980028 0 0 0 0 1483482 0 1306959 2319597 0 2027226 0 0 0 0 1552458 1554871 2159488 1879622 0 0 1383781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAITSLGHVTEGR MGYG000000258_01692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Ruminococcus_E|s__Ruminococcus_E bromii_B|m__MGYG000000258 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194053 0 0 309527 0 0 0 352603 0 0 0 279196 0 0 0 0 0 0 0 382510 0 0 0 0 0 0 0 0 0 0 299369 0 0 0 0 349627 0 0 401974 443112 0 348694 1073217 468657 0 906593 0 0 0 883600 0 0 0 1846971 0 0 0 284569 1506055 1136875 0 0 0 1216898 0 0 0 0 0 0 0 1211870 0 780233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAITTVLAK MGYG000000042_01421;MGYG000000138_00665;MGYG000000053_00908;MGYG000000412_01546;MGYG000004006_00433;MGYG000000074_01773;MGYG000001806_01406;MGYG000002535_04656;MGYG000002515_03208;MGYG000000273_00431;MGYG000004763_01689;MGYG000003184_03610;MGYG000001302.1_00073;MGYG000003363_01661;MGYG000003202_00129;MGYG000002281_02290;MGYG000002506_02966;MGYG000003546_00955;MGYG000002470_01245;MGYG000002514_02415;MGYG000000013_02251;MGYG000003394_01668;MGYG000002455_03884;MGYG000002507_00346;MGYG000002839_00878;MGYG000002515_03657;MGYG000001655_02933;MGYG000000044_01721;MGYG000004756_01173;MGYG000000196_03974;MGYG000002905_00001;MGYG000001661_02666;MGYG000002514_01953;MGYG000001789_00154;MGYG000000054_03933;MGYG000000236_01807;MGYG000003701_03123;MGYG000000098_02017;MGYG000002291_02272;MGYG000000170_00073;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000001346_01533;MGYG000000243_01988;MGYG000001780_03476;MGYG000001562_01075;MGYG000002540_03367;MGYG000000254_02569;MGYG000003279_00951;MGYG000001412_04734;MGYG000000414_00662;MGYG000001712_00119;MGYG000002418_00753;MGYG000000117_01463;MGYG000003535_00219;MGYG000002506_03686;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.288135593220339 976|Bacteroidetes 0.7457627118644068 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.8305084745762712 tuf 1.0 - 0.9491525423728814 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.9491525423728814 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 9084077 8917034 14619434 7128048 13438344 10643556 9494797 8942673 8814180 9397243 10201426 9176616 12083717 10828647 9440204 11412407 9841059 6877477 10740246 9553647 8804446 9027375 8267300 11220901 9527844 9898371 9106210 7559150 8316098 8952059 13765877 13559793 13721076 9380252 10251295 9873939 10848315 14167544 4216893 2601797 3930416 3183086 4195994 3313524 2898251 4055974 4543105 4417347 3897904 3289128 4260555 3663036 3791911 3299732 3942724 2045850 4846479 4041760 3840488 4005958 3311775 2318379 3907338 4065552 3170770 2529634 3099606 3799868 1598324 3855450 4001719 3060659 3922330 3264567 4120023 3329196 4119308 3532043 2512287 3893685 7376202 5944528 5445637 4256629 6497859 4031093 7000801 3373196 6262909 5184515 4000185 5071363 4403994 3864297 4349296 5139616 4968134 3717510 2236214 5936315 4573270 4053526 3746081 1566685 4581378 4921424 5524542 3267548 3596770 3032304 3983281 6033506 4222966 5472425 3769574 2499149 2752395 2553803 2997224 3498021 4035427 3114243 2992068 3321153 3112999 3710996 2754973 2835150 2897065 3304516 2871101 600532 2922729 3335063 5040553 1884076 207262 1885175 3209516 3162772 3961864 0 2781953 3495357 2497264 3357110 3007023 3355838 3665275 3945045 3622727 1977277 2366198 2549184 1726663 2393423 4405997 2558503 1505595 2523407 2072673 2022849 1813705 1919230 5309004 1258777 1674207 2695854 2155761 3434304 2816023 3176724 2405729 2663089 2854433 2075440 1573242 1463244 1723883 2710033 2450977 3977395 2307019 4108308 1428298 1697307 2069559 1453599 1820610 1716242 -AAITTVLAKK MGYG000000196_03974;MGYG000000236_01807;MGYG000000044_01721;MGYG000004763_01689;MGYG000001302.1_00073;MGYG000000243_01988;MGYG000000013_02251;MGYG000000170_00073;MGYG000003202_00129 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.4444444444444444 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAITTVLGK MGYG000000323_00619;MGYG000001313_00097;MGYG000001503_00139 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,4AZAI@81852|Enterococcaceae 0.3333333333333333 976|Bacteroidetes 0.6666666666666666 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.6666666666666666 - 1.0 ko:K02358 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140058 0 262738 0 0 0 0 0 1241824 0 0 0 927381 0 0 0 0 0 0 0 0 0 0 0 0 0 667967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 998018 0 0 1308142 1342151 904962 1235960 0 0 0 803351 0 0 0 0 0 0 990347 1057999 0 0 971149 0 0 0 0 0 0 0 0 0 0 918130 1099557 0 0 0 0 0 0 0 0 0 441010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 501143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIVAAC(Carbamidomethyl)QAK MGYG000003937_01474 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3WGMD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 3117979 3104265 2664575 2451578 3181347 3872306 0 3133318 2687151 2985546 3019782 3335455 3136719 2813644 3112381 3417083 2557771 6260744 0 4433306 3427140 3580596 4224238 1647012 0 2537414 2650835 4477688 2661931 2664882 1433159 2417576 2110149 2551085 3103560 2307555 2295805 2475168 573291 571446 494470 707951 582132 447427 0 676013 492935 375160 578325 639825 236122 544656 282328 301665 486650 623859 0 695255 278988 426103 833995 381116 0 471776 566966 0 409130 333166 634972 575921 533889 537009 390037 558524 754768 605716 385308 630905 504646 592959 0 602864 0 0 501598 0 0 348176 450691 0 0 0 138704 544026 0 416021 0 668543 177729 483624 0 206812 359259 1471231 611579 485095 489989 859042 0 162109 204622 322196 0 403809 542082 660188 617064 791123 860380 690443 0 576044 315719 689231 615152 1126892 632466 585927 454627 309412 371055 528776 0 463712 0 850302 115043 581510 0 0 551318 584794 0 524838 615824 914239 648490 260376 0 335625 358153 571401 0 127051 161745 0 0 227304 0 236515 246072 189780 182437 0 0 167778 287218 141369 167989 759990 0 0 375597 0 1096874 209655 0 0 0 777919 165150 0 101260 292004 0 97167 167298 0 227164 143346 -AAIVHGLK MGYG000003486_01280 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-95|s__CAG-95 sp000436115|m__MGYG000003486 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,268PI@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2942647 0 0 1966820 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2870727 0 0 0 3192714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3050255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIVIAVK MGYG000002274_02929;MGYG000000195_00114 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3WG8A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Participates in both transcription termination and antitermination 1.0 nusA 1.0 - 1.0 - 1.0 ko:K02600 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009,ko03021 1.0 - 1.0 - 1.0 - 1.0 KH_5,NusA_N,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492286 0 0 0 0 609494 0 0 0 0 394947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428718 0 0 0 0 310643 0 0 0 0 328458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 791942 0 0 0 0 749166 0 0 0 0 664536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257495 0 0 0 0 176200 0 0 0 0 320563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663644 0 0 0 0 738685 0 0 0 0 850315 0 0 0 0 0 0 0 0 0 0 -AAIWIEANVK MGYG000002506_01952;MGYG000002494_03988 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,1RMZJ@1236|Gammaproteobacteria,3XM48@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 P 1.0 peroxidase activity 1.0 yfeX 1.0 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020037,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1990748 1.0 - 1.0 ko:K07223 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Dyp_perox 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 210639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 393979 0 353437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 562641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 846332 0 642903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146021 0 349717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 197586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIYGHDANWGR MGYG000002517_01106;MGYG000004271_00865;MGYG000000133_01203;MGYG000000301_00744 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia 0.5 186801|Clostridia 1.0 E 1.0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate 1.0 argJ 1.0 - 1.0 2.3.1.1,2.3.1.35 1.0 ko:K00620 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028 1.0 R00259,R02282 1.0 RC00004,RC00064 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ArgJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 amino-acid N-acetyltransferase. | glutamate N-acetyltransferase. N-acetylglutamate synthase. | ornithine transacetylase. Also acts with L-aspartate and, more slowly, with some other amino acids. | Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity. acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate. | L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L- glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 779323 668388 0 0 0 819023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464666 0 403074 0 766631 0 0 0 0 509745 0 0 0 0 0 589121 0 256918 472429 0 0 0 199738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234276 0 247737 0 0 0 0 774080 0 0 0 0 0 232623 0 335413 459864 0 0 0 163117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447296 0 289221 0 287034 0 0 0 0 272883 0 0 0 0 0 479130 0 953387 485845 0 0 0 300313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402921 0 290653 0 1352649 0 0 0 0 430465 0 0 0 0 0 1216496 0 1491329 2411799 0 0 0 1358218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1827358 0 1476316 0 1336972 0 0 0 0 2384747 0 0 0 0 0 1989700 0 -AAIYGSSSSDYALGLK MGYG000001421_00850 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__Dielma|s__Dielma fastidiosa|m__MGYG000001421 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 PFAM Extracellular ligand-binding receptor 1.0 - 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Peripla_BP_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1109597 0 0 0 0 0 0 0 0 -AAIYHR MGYG000000074_01490 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0612@1|root,COG0612@2|Bacteria,4NDXM@976|Bacteroidetes,2FNQC@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Belongs to the peptidase M16 family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M16C_assoc,Peptidase_M16,Peptidase_M16_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIYNGLQVK MGYG000000105_02450;MGYG000003681_00109;MGYG000000236_01485;MGYG000000098_00605 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,2FMPI@200643|Bacteroidia,4AP54@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;RNA degradation;Central carbon metabolism in cancer;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;AMPK signaling pathway;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269348 0 0 0 0 0 0 0 423329 0 0 0 0 0 0 0 408174 0 217427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 558954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225887 0 452286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIYNLATGTVK MGYG000003899_01066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539945|m__MGYG000003899 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 3784396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5181048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3766846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6586528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1333244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIYNLGFGTAK MGYG000001300_01291 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 341401 0 433536 300460 0 0 0 0 0 0 0 0 332875 522055 0 577397 222797 0 260383 0 181877 0 370558 0 0 0 0 0 0 0 0 0 0 354289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 483552 0 1524038 0 0 1782031 2017832 2504377 2052779 0 0 0 0 0 0 0 0 2611560 1889015 0 3044753 2355282 0 2381075 0 1588250 0 1944242 0 0 0 0 0 0 0 0 0 0 2060485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAIYSGEK MGYG000001780_00304;MGYG000004876_01447;MGYG000002478_02197 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 660131 0 478000 986828 980794 875553 1074321 0 760459 0 925276 716781 0 890073 674077 1706197 828695 1102083 447585 988631 769559 1078319 1021119 1110913 637501 727896 0 848747 937475 0 940735 1234123 398712 369326 839976 1080544 777948 696419 1255218 0 1080317 1256933 1066154 881174 727393 0 752980 0 1056636 938444 0 1163748 766133 1672470 818068 0 905034 798263 881568 949321 1531469 695895 816688 951613 0 1333946 867673 0 1393345 896513 883960 866442 1257674 815451 1047561 669545 821217 0 559305 676141 1112505 818258 830321 0 909424 0 665992 728504 0 721264 705415 565095 921939 1075879 504037 596622 722075 597882 1555334 723379 697491 719541 0 905926 928875 0 933367 539910 265225 564592 1198314 908593 750781 757244 399446 0 507826 440174 320241 444655 386062 0 484237 0 365940 1214814 0 309555 147843 315036 519915 676181 256900 300926 201087 466113 224539 335880 319977 179790 0 1011390 321627 0 888405 480584 606313 273716 325719 622468 288746 289768 1668091 0 1083778 1195379 2391892 1314302 1319288 0 1492912 0 1015372 1060967 0 1252365 1475221 1987782 1274950 3260284 1177112 1922734 1311496 1535454 3802287 1697063 1934207 1819414 0 2237926 1379256 0 1683110 1583345 1196119 1983025 1520506 1698856 1682002 1281763 -AAIYSGEKGYEELC(Carbamidomethyl)K MGYG000002478_02197 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 425567 0 0 0 305716 492576 0 0 0 0 0 0 0 0 0 892014 0 0 0 0 0 326460 0 592429 0 591717 0 0 192811 0 620884 576509 0 255104 0 0 294131 0 298930 0 0 0 481777 280037 0 0 0 0 0 0 0 0 0 883589 0 0 0 0 0 213650 0 195349 0 279782 0 0 456856 0 593022 542287 0 278396 0 0 301007 0 393552 0 0 0 474825 420015 0 0 0 0 0 0 0 0 0 480447 0 0 0 0 0 355463 0 283905 0 231947 0 0 355653 0 543218 193976 0 222328 0 0 305607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174127 0 0 0 0 0 0 0 0 0 0 0 0 704970 0 0 0 1431741 1005162 0 0 0 0 0 0 0 0 0 932290 0 0 0 0 0 627386 0 2398386 0 736029 0 0 746710 0 672755 1854944 0 625461 0 0 993285 0 -AAK(Lys->Ala)PAAPK MGYG000000074_01933 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,2FNPH@200643|Bacteroidia,22UFD@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal protein L17 1.0 rplQ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02879 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Ribosomal_L17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140459 0 82540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8211582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKAAEAEAAR MGYG000004681_01708;MGYG000002961_00396 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0254@1|root,COG0254@2|Bacteria,2HUWQ@201174|Actinobacteria,4CVW5@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Binds the 23S rRNA 1.0 rpmE 1.0 - 1.0 - 1.0 ko:K02909 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L31 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKAD(Methyl[D](Asp->Glu)GITGEVLLQNLEC(Carbamidomethyl)R MGYG000002293_00480 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,2FMRC@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 503762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKADSIEVR MGYG000004158_00690 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister invisus|m__MGYG000004158 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TSVA@1239|Firmicutes,4H24P@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 - 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKAEGITGEVLLQNLEC(Carbamidomethyl)R MGYG000003697_01442 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,2FMRC@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 457798 0 0 277762 0 0 0 0 347800 0 0 0 0 0 0 0 0 0 0 396936 0 193915 0 0 0 0 0 0 0 197163 163454 0 0 0 0 141599 0 0 275781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 484628 0 0 472396 0 0 0 0 533514 0 0 0 0 0 0 326000 0 0 0 371872 1061653 269605 0 0 0 269604 0 0 0 399968 0 0 0 0 0 394591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKAETEAAATEEAPAAEATEAPAEA MGYG000000243_01032 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 2778322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1992511 0 0 0 0 2103779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKDFATVITVDDQGNIK MGYG000002143_00771 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900545585|m__MGYG000002143 1.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,267P3@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate-binding protein PnrA-like 1.0 tmpC 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 109131 0 0 118271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468816 0 382012 0 0 0 0 0 0 0 0 212284 0 0 0 0 0 0 0 590265 0 0 568103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428746 0 497628 0 0 0 0 0 0 0 0 449357 0 0 0 0 446537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320253 0 99307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKDNVVTTPGYDSSAYPR MGYG000003681_03037 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4APMN@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKEELKPEVYIQYQGR MGYG000002517_02585 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 210348 452592 0 295240 0 251717 0 166844 0 214777 0 0 235115 0 266251 0 311556 0 0 211917 0 0 158552 0 262109 0 0 0 0 0 0 0 0 280601 238636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172010 0 0 229637 0 0 0 122335 0 190556 0 0 0 0 240402 0 192463 0 195547 0 0 0 0 0 0 474186 0 0 0 0 0 0 0 0 0 99083 322809 0 1222157 96815 0 938036 0 522338 0 873548 728362 219652 217250 259991 0 1000079 770713 0 370478 0 448214 0 946000 0 0 0 835344 659302 905039 0 0 0 0 0 0 452622 0 993764 744036 0 674143 899336 1079469 0 0 670367 0 535523 584465 1411770 999228 660874 0 933968 1320076 0 999518 0 881853 0 932160 726587 0 1248104 854246 434889 810160 0 0 0 0 0 1379099 819566 0 769541 768733 991239 -AAKEQNIATAILVGDEAK MGYG000001315_01872 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Phosphate acetyl butaryl transferase 1.0 ptb 1.0 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747,GO:0050182 1.0 2.3.1.19 1.0 ko:K00634 1.0 ko00650,ko01100,map00650,map01100 1.0 - 1.0 R01174 1.0 RC00004,RC02816 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphate butyryltransferase. phosphotransbutyrylase. - butanoyl-CoA + phosphate = butanoyl phosphate + CoA. 1.0 1.0 1.0 1.0 Butanoate metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKERC(Carbamidomethyl)DAGFGVNNTGLAVFLDFSEAINR MGYG000000196_02827 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKGEKDYYR MGYG000000223_00603 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0747@1|root,COG0747@2|Bacteria 1.0 2|Bacteria 1.0 E 1.0 dipeptide transport 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521541 0 0 0 0 0 0 0 0 816911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKGGTLDEVIEAAQK MGYG000004735_02294 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,21YFJ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 2.7.1.121 1.0 ko:K05878 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 1562652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 862618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKLNVVYEK MGYG000000245_00061;MGYG000000404_00348 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 1.0 183925|Methanobacteria 1.0 F 1.0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 1.0 purD 1.0 - 1.0 6.3.4.13 1.0 ko:K01945 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04144 1.0 RC00090,RC00166 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKM(Oxidation)DSSSEITK MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 155112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207855 0 212998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247569 0 290982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAKTADEKPEK MGYG000001300_02380 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position 1.0 glgB 1.0 - 1.0 2.4.1.18 1.0 ko:K00700 1.0 ko00500,ko01100,ko01110,map00500,map01100,map01110 1.0 M00565 1.0 R02110 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 CBM48,GH13 1.0 - 1.0 Alpha-amylase,Alpha-amylase_C,CBM_48 1.0 2.4.1.18 1.0 CBM48 1.0 GH13+CBM48 1.0 CBM48+GH13_9 1.0 1,4-alpha-glucan branching enzyme. glycogen branching enzyme. Converts amylose into amylopectin.-!-The description (official name) requires a qualification depending on the product, glycogen or amylopectin, e.g. glycogen branching enzyme, amylopectin branching enzyme.-!-The latter has frequently been termed Q-enzyme. Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. 1.0 1.0 1.0 1.0 Metabolic pathways;Biosynthesis of secondary metabolites;Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134738 0 -AAL(Xle->Gln)MDEWFSGK MGYG000002080_01068 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900544825|m__MGYG000002080 1.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the transketolase family 1.0 tkt 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 938315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAL(Xle->Val)VHGLK MGYG000002528_01864;MGYG000002756_00379;MGYG000002596_01649;MGYG000003215_00849;MGYG000004055_01475;MGYG000003500_00156;MGYG000004735_02050;MGYG000001141_01291;MGYG000002212_00566;MGYG000000164_02739;MGYG000003786_01019;MGYG000000204_02185;MGYG000001374_01171;MGYG000001689_04166;MGYG000002141_01720;MGYG000003486_01280;MGYG000001793_01089;MGYG000000078_01647;MGYG000004558_00350;MGYG000000278_00938;MGYG000002835_01005;MGYG000003442_01319;MGYG000004359_01015;MGYG000000139_02422;MGYG000001619_00808;MGYG000001493_03358;MGYG000000080_02280;MGYG000000028_01597;MGYG000004879_02709 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,25QPE@186804|Peptostreptococcaceae 0.27586206896551724 186801|Clostridia 1.0 J 0.7241379310344828 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.41379310344827586 rpsK 0.41379310344827586 - 1.0 - 1.0 ko:K02948 0.41379310344827586 ko03010,map03010 0.7241379310344828 M00178,M00179 0.7241379310344828 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.7241379310344828 - 1.0 - 1.0 - 0.7241379310344828 Ribosomal_S11 0.41379310344827586 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.7241379310344828 none 1.0 0 0 0 0 738387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAAAEGDYK MGYG000000437_00955;MGYG000000074_00133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3590720 0 0 0 2908334 0 0 0 2339026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2266625 0 2516072 0 0 0 2155420 0 0 0 2677945 0 0 0 0 416584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 473309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAAAGVPVVYTGPVDR MGYG000003683_01311 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4CZ2W@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 M 1.0 UDP-galactopyranose mutase 1.0 glf 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 1.0 5.4.99.9 1.0 ko:K01854 1.0 ko00052,ko00520,map00052,map00520 1.0 - 1.0 R00505,R09009 1.0 RC00317,RC02396 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iNJ661.Rv3809c 1.0 GLF,NAD_binding_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 UDP-galactopyranose mutase. - - UDP-alpha-D-galactose = UDP-alpha-D-galactofuranose. 1.0 1.0 1.0 1.0 Galactose metabolism;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332280 0 0 0 0 0 0 0 0 0 0 0 707021 0 0 0 0 0 624175 0 0 0 512684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAAEIPADLK MGYG000004769_01202 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,4H2K7@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 152202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 600323 0 0 0 0 590236 0 0 749067 0 0 0 0 494931 399581 0 0 0 0 0 0 0 0 0 464821 0 0 0 554949 708561 519163 0 0 382912 0 497807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAAGGEAAK MGYG000002494_01061 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 28I6Q@1|root,2Z89M@2|Bacteria,1MWCS@1224|Proteobacteria,1RN42@1236|Gammaproteobacteria,3WV68@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Protein of unknown function (DUF1471) 1.0 ydgH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1471 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 966213 727069 0 872631 2516150 0 0 0 917074 0 0 0 0 914464 0 0 0 0 0 1104134 710263 0 765775 0 0 0 0 1083592 1071654 0 0 771468 0 0 0 0 0 0 2224555 3522890 0 2577164 4997838 0 0 0 2851773 0 0 0 0 1513789 0 0 0 0 0 3243536 5122623 0 3665789 0 0 0 0 3910255 2601995 0 0 4032073 0 0 0 0 1551970 0 211851 0 0 0 622947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 737768 0 0 0 0 0 0 0 265957 0 0 0 0 0 0 0 0 0 0 735417 0 0 848185 0 0 0 804251 0 0 0 0 765385 0 0 0 0 0 0 1123637 0 1153927 0 0 0 0 0 325113 0 0 622477 0 0 0 0 707039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALADYK MGYG000004628_01120 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__|m__MGYG000004628 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 - 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 908696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAEAQEVK MGYG000003697_01183;MGYG000002293_01687 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,2FNR9@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the ATCase OTCase family 1.0 argF 1.0 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.1.3.11,2.1.3.9 1.0 ko:K09065,ko:K13043 1.0 ko00220,ko01100,ko01230,map00220,map01100,map01230 1.0 M00845 1.0 R07245,R08937 1.0 RC00096 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 N-succinylornithine carbamoyltransferase. | N-acetylornithine carbamoyltransferase. succinylornithine transcarbamylase. | N-acetylornithine transcarbamylase. Specific for N-succinyl-L-ornithine and cannot use either L-ornithine (see EC 2.1.3.3) or N-acetyl-L-ornithine (see EC 2.1.3.9) as substrate.-!-However, a single amino-acid substitution (Pro90Glu) is sufficient to switch the enzyme to one that uses N-acetyl-L-ornithine as substrate.-!-It is essential for de novo arginine biosynthesis in the obligate anaerobe Bacteroides fragilis, suggesting that this organism uses an alternative pathway for synthesizing arginine. | Differs from EC 2.1.3.3.-!-This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic pathway of several eubacteria and has no catalytic activity with L-ornithine as substrate. carbamoyl phosphate + N(2)-succinyl-L-ornithine = H(+) + N(2)-succinyl-L- citrulline + phosphate. | carbamoyl phosphate + N(2)-acetyl-L-ornithine = H(+) + N(2)-acetyl-L- citrulline + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2619541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAELSK MGYG000000074_01070 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG0457@2|Bacteria,4PESY@976|Bacteroidetes,2G21B@200643|Bacteroidia,22UIH@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 625174 0 0 761938 0 0 0 0 0 0 0 645638 0 0 445492 0 225685 0 0 529240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 800430 0 0 830728 0 0 0 0 778293 0 0 356543 0 0 728734 0 392744 0 0 911488 0 0 0 0 0 642455 0 0 0 456306 560080 0 0 0 0 0 661276 0 279198 0 0 0 0 0 0 0 498698 0 0 0 0 0 0 0 0 0 0 597546 0 0 0 0 0 0 0 0 0 0 309755 0 0 0 0 0 0 0 414774 0 0 219691 0 0 0 0 414084 0 0 163392 0 0 0 0 0 0 0 716422 0 0 0 0 0 528639 0 0 0 334283 184515 0 0 0 0 0 393575 0 2549367 0 0 2930800 0 0 0 0 2797146 0 0 2661911 0 0 2129224 0 2676854 0 0 4261168 0 0 0 0 0 3597373 0 0 0 4693019 1704910 0 0 0 0 0 2710037 0 -AALAGAK MGYG000000045_02628 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG0126@1|root,COG0126@2|Bacteria,2NNN1@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 G 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iSB619.SA_RS04145 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 152618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 570038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1190036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAGFADVK MGYG000001319_02401 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,4BW9Z@830|Butyrivibrio 1.0 186801|Clostridia 1.0 E 1.0 Threonine synthase N terminus 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1136860 0 0 0 0 1396587 0 0 0 0 1224072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141613 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 551210 0 0 0 0 596286 0 0 0 0 491258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132808 0 0 0 0 664278 0 0 0 0 687642 0 0 0 0 0 0 0 0 0 0 -AALAGFADVPGTK MGYG000002528_02105;MGYG000000080_00353;MGYG000000262_02109;MGYG000001379_01833 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,2685I@186813|unclassified Clostridiales 0.5 186801|Clostridia 1.0 E 1.0 Threonine synthase N terminus 0.75 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 611855 0 0 0 659171 0 0 0 0 0 0 0 0 0 0 364676 0 0 0 0 968449 0 209840 0 0 0 0 1005979 0 0 0 0 0 0 0 0 0 0 839551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 820805 0 0 0 0 0 0 0 0 0 0 2889101 0 0 0 1324525 0 0 0 0 0 0 0 0 0 0 1712878 0 0 0 0 3218645 0 956676 0 0 0 0 1670518 0 0 0 0 0 0 0 0 0 0 780969 0 0 0 442186 0 0 0 0 0 0 0 0 0 0 611389 0 0 0 0 511871 0 656530 0 0 0 0 2202195 0 0 0 0 0 0 0 0 0 0 268414 0 0 0 811057 0 0 0 0 0 0 0 0 0 0 462901 0 0 0 0 522717 0 478770 0 0 0 0 1099013 0 0 0 0 0 0 0 0 0 -AALAGFADVPGTR MGYG000004733_03061;MGYG000000171_00617 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3XZ3J@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 8.87 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 1144848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 812562 0 770145 0 0 0 0 763835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 586063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 846621 0 932795 0 0 0 0 1132151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 315061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAGFSDVPGTK MGYG000002517_01577 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Threonine synthase 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 1199378 684368 811378 1316763 834923 1063716 966579 1393852 1106940 1696436 643452 759416 372671 1061939 1330419 818646 1142672 0 1344476 1205850 1326695 1113648 0 536306 1286085 1224198 994164 0 302268 980478 353529 738336 533715 1292755 1231209 965395 987651 479097 6516858 15406084 0 1371426 0 803407 1245571 1337915 0 3292310 2186087 2078427 5235945 1032010 650088 3248036 4656987 0 2766838 4936028 3825355 1601373 0 6259809 5191176 1426762 2850245 0 9894837 1775936 0 7547867 4435195 8148302 310353 2648266 0 0 589142 577467 397339 521162 151691 140133 477211 307558 432285 650544 679203 0 202257 131083 601552 336834 686056 0 493122 678258 545705 15125633 0 542453 848859 796253 390476 0 257234 510245 421489 12455539 0 417413 1096454 341103 548949 10287638 6084004 0 2524027 4347723 0 2647038 3064964 5668920 5047465 3126431 3271261 2638826 2392281 5443142 5311927 3007995 3901512 0 3601607 4785805 3307019 2026369 0 2105333 4387189 4178705 4796413 0 2074259 3751569 4542227 565721 2694319 3022780 4572985 3929670 6784327 3115630 2741262 1849087 3029354 150737 2306816 3605901 2857191 2751679 3361236 3808682 2139091 2942269 1523763 3097950 4346014 0 3983939 0 2723897 3040844 3443511 2614091 0 4865134 3979178 3101744 2710655 0 580339 2574616 2404981 1194022 2717612 3018412 2537706 3708362 3776716 3015517 -AALAGGLK MGYG000003937_01848 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAGGLKPIIC(Carbamidomethyl)VGESLDQR MGYG000003921_00579;MGYG000001157_01821 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 354155 0 0 0 0 0 296409 0 0 0 0 241264 0 0 0 0 298384 0 269144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1603098 0 0 0 0 0 923462 0 0 0 0 926856 0 0 0 0 685355 0 915271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532026 0 0 0 0 0 199177 0 0 0 0 288340 0 0 0 0 266414 0 257023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633661 0 0 0 0 0 270455 0 0 0 0 0 0 0 0 0 0 0 418406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1171013 0 0 0 0 0 1024514 0 0 0 0 1155128 0 0 0 0 1234348 0 760359 0 0 0 0 0 0 0 0 -AALANAALNAER MGYG000000591_01538;MGYG000001365_01289 genus d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A 1.0 COG0845@1|root,COG0845@2|Bacteria,1TQV0@1239|Firmicutes,4H1W4@909932|Negativicutes 1.0 909932|Negativicutes 1.0 M 1.0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1049371 0 0 0 0 0 0 1009898 0 0 909186 0 975828 0 0 0 1041989 673340 936187 0 0 0 765838 0 0 1430483 0 0 0 0 0 0 0 -AALANAR MGYG000003683_00464;MGYG000000003_01871 domain d__Bacteria 1.0 COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales 0.5 201174|Actinobacteria 0.5 H 0.5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 0.5 tal 0.5 - 1.0 2.2.1.2 0.5 ko:K00616 0.5 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 0.5 M00004,M00007 0.5 R01827 0.5 RC00439,RC00604 0.5 ko00000,ko00001,ko00002,ko01000 0.5 - 1.0 - 1.0 - 1.0 TAL_FSA 0.5 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 0.5 0.5 0.5 0.5 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALANDSFLSAASFQETTR MGYG000001300_00284;MGYG000001255_01103 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 211088 0 468816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306631 0 0 0 0 0 0 0 335158 0 0 0 0 330659 893642 610374 441176 1065938 527112 642789 938703 453418 739541 0 498703 649069 0 861978 0 0 1056926 0 1007016 969493 0 741050 0 683336 986641 998006 743943 0 0 462962 714220 0 770631 669276 0 705071 689866 469478 0 381504 0 0 0 333823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313480 0 0 0 0 254183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALANIFSELPNSEK MGYG000002494_04301 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,3WWIY@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication 1.0 ygfZ 1.0 GO:0003674,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0019842,GO:0022607,GO:0031163,GO:0031406,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071840,GO:0072341,GO:0097159,GO:1901363 1.0 - 1.0 ko:K06980 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03016 1.0 - 1.0 - 1.0 - 1.0 GCV_T,GCV_T_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 233145 0 0 0 0 0 0 0 727628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 801803 0 0 0 0 538428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALANMVQAAQNLR MGYG000002506_03505 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,3XP3E@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation 1.0 metE 1.0 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.1.1.14 1.0 ko:K00549 1.0 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 1.0 M00017 1.0 R04405,R09365 1.0 RC00035,RC00113,RC01241 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 1.0 Meth_synt_1,Meth_synt_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. tetrahydropteroylglutamate-homocysteine transmethylase. Requires phosphate.-!-The enzyme from Escherichia coli also requires a reducing system.-!-Unlike EC 2.1.1.13 this enzyme does not contain cobalamin. 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Selenocompound metabolism;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1493668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1594868 0 1727056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAPDAFQR MGYG000001306_03308;MGYG000001783_02428 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3522657 0 0 0 0 3303324 0 0 0 0 3740081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 668831 0 0 0 0 1022394 0 0 0 0 1119958 0 0 0 0 0 0 0 0 0 0 -AALAQFVGK(Lys->Arg) MGYG000000262_01263 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,25UYQ@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsI 1.0 - 1.0 2.7.3.9,2.7.9.2 1.0 ko:K01007,ko:K08483 1.0 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060 1.0 M00173,M00374 1.0 R00199 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--protein phosphotransferase. | pyruvate, water dikinase. sugar--PEP phosphotransferase enzyme I. | pyruvate,water dikinase. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. | ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Phosphotransferase system (PTS);Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3007794 0 0 0 2084736 0 0 0 0 0 0 0 0 0 0 2727032 0 1961270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 591322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAQILVK MGYG000002438_01767 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG3063@1|root,COG3063@2|Bacteria,4PKG6@976|Bacteroidetes,2G3G2@200643|Bacteroidia,2322F@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 NU 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2260438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAQVEK MGYG000002992_02024;MGYG000000198_04879;MGYG000001496_02754;MGYG000002279_02611;MGYG000001789_02120 domain d__Bacteria 1.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,27VNQ@189330|Dorea 0.4 186801|Clostridia 0.8 U 0.8 Preprotein translocase subunit 0.8 yajC 0.8 - 1.0 - 0.8 ko:K03210 0.8 ko02024,ko03060,ko03070,map02024,map03060,map03070 0.8 M00335 0.8 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 0.8 3.A.5.1,3.A.5.2 0.8 - 1.0 - 1.0 Ftsk_gamma,YajC 0.8 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8 0.8 0.8 0.8 Protein export;Quorum sensing;Bacterial secretion system 0.8 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALATESFLSAASFQETTR MGYG000003474_00162 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__QALW01|g__UMGS1322|s__|m__MGYG000003474 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,36EQT@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALAVC(Carbamidomethyl)K MGYG000001338_02425;MGYG000002966_01691;MGYG000000184_00685 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism;Carbon metabolism 1.0 none 1.0 0 693086 2289228 0 3707915 0 0 1932430 0 0 2548945 0 0 0 0 2791339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1178721 2915237 1577755 0 0 0 0 2205377 0 8305391 2406650 0 3289220 0 0 2026142 0 0 2524176 0 0 0 0 1953403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6082149 3935857 2061902 0 0 0 0 1119463 0 4873660 1850658 0 575920 0 0 2534302 0 0 1944151 0 0 0 0 2573464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1568260 4257263 3363287 0 0 0 0 2182801 0 4378384 3728427 0 6664444 0 0 2174252 0 0 2816815 0 0 0 0 2403452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6972213 5241133 4611477 0 0 0 0 5039745 0 7373424 5731163 0 2773006 0 0 2539007 0 0 4596771 0 0 0 0 3585023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7419413 6937284 6497517 0 0 0 0 5078291 -AALAVQAK MGYG000000077_02459;MGYG000004784_01123;MGYG000000262_01988 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25VEG@186806|Eubacteriaceae 0.6666666666666666 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.6666666666666666 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1823239 1987652 2744749 1264181 3615779 2130197 1163671 1857930 1314245 1651384 2438726 2075405 3685991 2363490 2311564 3225047 1398742 0 2579205 2013254 1924443 3086709 0 1406880 2550908 2053279 1603904 0 0 0 0 2043031 2101320 2524283 2194136 0 1670442 2290199 2380820 2275224 837873 1654456 805027 884814 3016759 1691944 1780092 870598 837336 914431 988366 1005022 1683263 596383 987442 0 1820458 2110251 1330633 705751 0 1727084 1152104 1650112 1411576 0 0 0 0 953119 632857 1965666 2126433 0 0 983669 6252158 8884319 4355070 10576297 3586652 6270858 3714956 6989230 5406180 6811631 5017193 3590022 6909236 6861524 7814270 6198278 6017580 0 7208367 8099334 6077458 9080951 0 4638360 7686999 6613995 7711536 0 0 0 0 6503681 4163149 7592053 6968662 0 5848596 2620804 3040331 2750846 3552932 4010858 3487868 2328235 2584749 3024390 1817200 4076738 0 3168985 3733782 2198610 2962329 5389259 4026363 0 2565841 2547798 2415025 3216889 0 3381749 1913365 1638279 2418905 0 0 0 0 2815602 3909645 1820075 2997170 0 2724224 3006363 623779 1790799 2471373 1270200 793888 1634172 620692 1270492 908840 828183 2978853 1110012 1399163 1114657 707556 2092317 860690 0 740958 431428 580434 2063902 0 2268771 1185741 687356 622007 0 0 0 0 1928511 3306849 716250 884492 0 628814 2049853 -AALC(Carbamidomethyl)SDC(Carbamidomethyl)FSAEATR MGYG000002298_00410 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp000436615|m__MGYG000002298 1.0 COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3XZXS@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 rpiB 1.0 - 1.0 5.3.1.6 1.0 ko:K01808 1.0 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01056,R09030 1.0 RC00376,RC00434 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 LacAB_rpiB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-5-phosphate isomerase. ribose phosphate isomerase. Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate. aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 575455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531057 0 395649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALC(Carbamidomethyl)SDTFSAHATR MGYG000002528_01063 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0394@1|root,COG0698@1|root,COG0394@2|Bacteria,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,268XB@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Ribose/Galactose Isomerase 1.0 rpiB 1.0 - 1.0 5.3.1.6 1.0 ko:K01808 1.0 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01056,R09030 1.0 RC00376,RC00434 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 LMWPc,LacAB_rpiB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-5-phosphate isomerase. ribose phosphate isomerase. Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate. aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 128385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALC(Carbamidomethyl)TDC(Carbamidomethyl)FC(Carbamidomethyl)AEATR MGYG000004735_01991 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3XZXS@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 rpiB 1.0 - 1.0 5.3.1.6 1.0 ko:K01808 1.0 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01056,R09030 1.0 RC00376,RC00434 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 LacAB_rpiB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-5-phosphate isomerase. ribose phosphate isomerase. Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate. aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDAC(Carbamidomethyl)SSSFDIR MGYG000000133_02045 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3XZ9K@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location CytoplasmicMembrane, score 1.0 ntpI 1.0 - 1.0 - 1.0 ko:K02123 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 V_ATPase_I 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 428664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1215047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDAGSAAAQR MGYG000002477_02054;MGYG000002494_03995 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1RCBV@1224|Proteobacteria,1S2HK@1236|Gammaproteobacteria,3WVJ5@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 CQ 1.0 Ethanolamine utilization protein EutK C-terminus 1.0 eutK 1.0 GO:0003674,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0031469,GO:0031471,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0050896 1.0 - 1.0 ko:K04025 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC,EutK_C,HTH_IclR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 984652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 932078 0 0 0 0 723482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDAIYHAGK MGYG000000179_03466 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1527@1|root,COG1527@2|Bacteria,1U6WZ@1239|Firmicutes,249XD@186801|Clostridia,267RG@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 ATP synthase (C/AC39) subunit 1.0 ntpC 1.0 - 1.0 - 1.0 ko:K02119 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 DUF2764,vATP-synt_AC39 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 735400 518323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDALER MGYG000002478_02977;MGYG000004797_03856;MGYG000000243_01217 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,2FN0X@200643|Bacteroidia,4AN0A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the PdxA family 1.0 pdxA 1.0 - 1.0 1.1.1.262 1.0 ko:K00097 1.0 ko00750,ko01100,map00750,map01100 1.0 M00124 1.0 R05681,R05837,R07406 1.0 RC00089,RC00675,RC01475 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PdxA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxythreonine-4-phosphate dehydrogenase. NAD(+)-dependent threonine 4-phosphate dehydrogenase. The enzyme is part of the biosynthesis pathway of the cofactor pyridoxal 5'-phosphate found in anaerobic bacteria. 4-(phosphooxy)-L-threonine + NAD(+) = 3-amino-2-oxopropyl phosphate + CO2 + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1239770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 658355 0 0 1451316 0 0 0 0 851653 0 1646593 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432470 0 0 0 0 0 0 0 0 0 456569 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 691522 0 0 0 0 618042 0 0 0 0 0 0 0 468388 0 0 0 0 184019 0 293680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDATTNALK MGYG000003697_01550;MGYG000002834_01007 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3704416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1687414 0 0 0 0 2359449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDAYYEQYGAK MGYG000002528_00495;MGYG000000184_02212;MGYG000001338_00074 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,3WGS1@541000|Ruminococcaceae 0.3333333333333333 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1799899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2047922 0 0 0 0 0 0 -AALDEVGEEQHR MGYG000002794_00763;MGYG000002926_00664;MGYG000002882_00085;MGYG000002720_00861;MGYG000002143_01959;MGYG000001733_00672;MGYG000004196_01673;MGYG000004475_00752;MGYG000004487_00297;MGYG000002086_01355 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 2635207 1918916 1539996 2020297 1234816 2197549 2755175 2387776 2584108 2167687 1403252 1441908 1363531 2274396 1951392 1388084 1409946 1286781 1678253 1928238 2127638 2040667 1149928 2068017 2194530 3031222 1911328 1494318 2333425 1330192 1880363 1327018 1626870 2432534 2080261 2444948 2596190 1549066 492309 56280 0 466204 270691 169099 457162 551596 406348 390685 52751 242298 84461 364190 374037 98739 191495 0 535727 549501 231101 0 81366 202834 290214 460095 514703 105495 349157 247938 177883 131857 117075 420666 391844 470521 556882 313467 1736263 1389776 1123844 1712733 580940 706753 1702447 2068051 1453116 1657876 841108 1213739 1062062 1793136 1749358 1071140 1562359 271991 1686861 1641400 1811705 1350557 342149 860902 1586523 1893767 1818700 449063 1553363 1707751 614658 915062 1284481 1853829 1160265 1505628 1027434 1214950 921357 978351 852514 1007763 805957 1083159 1189972 1135266 1268196 1271015 616390 647560 634174 1200040 990825 816685 1558529 203463 1200624 996684 771234 810696 242581 866503 1069634 1003615 1101393 318513 1384567 772741 765559 943652 1032399 1399466 857751 1034447 1120070 811800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94465 260077 600759 0 0 0 736259 0 0 0 0 0 333929 0 0 0 0 -AALDGAYEQWR MGYG000002478_01888 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 2DBE2@1|root,2Z8QB@2|Bacteria,4NK8H@976|Bacteroidetes,2FMIR@200643|Bacteroidia,4AP06@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 798801 0 0 0 0 1299559 0 0 0 0 1224140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1026019 0 0 0 0 1143901 0 0 0 0 1142646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 669661 0 0 0 0 467215 0 0 0 0 560839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246266 0 0 0 0 412025 0 0 0 0 161809 0 0 0 0 0 0 0 0 0 0 -AALDHQQER MGYG000003683_00678 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CYWE@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 F 1.0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates 1.0 pyrG 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.0 6.3.4.2 1.0 ko:K01937 1.0 ko00240,ko01100,map00240,map01100 1.0 M00052 1.0 R00571,R00573 1.0 RC00010,RC00074 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iNJ661.Rv1699 1.0 CTP_synth_N,GATase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CTP synthase (glutamine hydrolyzing). UTP--ammonia ligase. The enzyme contains three functionally distinct sites: an allosteric GTP-binding site, a glutaminase site where glutamine hydrolysis occurs (cf. EC 3.5.1.2), and the active site where CTP synthesis takes place.-!-The reaction proceeds via phosphorylation of UTP by ATP to give an activated intermediate 4-phosphoryl UTP and ADP.-!-Ammonia then reacts with this intermediate generating CTP and a phosphate.-!-The enzyme can also use ammonia from the surrounding solution. ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1278017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 266076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDIATDPWGIK MGYG000000251_01623;MGYG000000217_00189 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3WH9Z@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 O 1.0 SPFH Band 7 PHB domain protein 0.5 qmcA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Band_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 698654 0 0 0 0 960837 0 0 0 0 1034191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402491 0 0 0 0 572023 0 0 0 0 523925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDKYGSGC(Carbamidomethyl)AGSR MGYG000002293_02198;MGYG000002960_00103;MGYG000002603_02013;MGYG000002834_01646;MGYG000003697_02473 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FM0N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 8-amino-7-oxononanoate synthase 1.0 bioF 1.0 - 1.0 2.3.1.29,2.3.1.47 1.0 ko:K00639,ko:K00652 1.0 ko00260,ko00780,ko01100,map00260,map00780,map01100 1.0 M00123,M00573,M00577 1.0 R00371,R03210,R10124 1.0 RC00004,RC00039,RC00394,RC02725 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine C-acetyltransferase. | 8-amino-7-oxononanoate synthase. 2-amino-3-ketobutyrate coenzyme A ligase. | AONS. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. | The enzyme catalyzes the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis.-!-Pimeloyl-CoA can be used with lower efficiency. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. | 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism;Metabolic pathways;Biotin metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 264385 0 0 0 0 0 0 256826 0 0 0 0 0 0 0 0 0 102267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1648561 0 0 1560464 0 0 0 0 1368942 0 0 0 0 0 0 1803861 0 0 0 1944203 1890745 1376647 0 0 0 1055183 0 0 0 0 1368940 0 0 0 0 1296964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDNFYAR MGYG000002933_01923;MGYG000001783_01377;MGYG000001306_01721;MGYG000002478_00089;MGYG000000243_01768 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,2FM2Z@200643|Bacteroidia,4AN6Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate 1.0 purL 1.0 - 1.0 6.3.5.3 1.0 ko:K01952 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04463 1.0 RC00010,RC01160 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C,GATase_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylformylglycinamidine synthase. phosphoribosylformylglycinamidine synthetase. - ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D- ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D- ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 2060149 0 3461956 1909271 2503296 1852751 1978514 1829622 1862875 0 1437606 2008013 2747920 1819441 1677907 2808353 1913285 1271556 1721364 2011752 1977002 1592425 1673873 2408022 1626820 1824234 0 1640823 0 2199680 3471491 2141641 3494825 0 0 2196527 1740977 3309520 738520 0 963706 989790 1257211 641329 856930 903503 907619 0 589495 732349 2577308 813359 677675 2078344 372183 1520450 774460 892656 982066 880441 2450039 701875 1075688 986139 0 1507546 0 790639 679206 737114 1209275 0 0 778613 842069 1022862 690870 0 772931 625825 938150 810475 702869 309253 714551 0 491388 872511 1461364 456251 370311 1020358 648180 1275613 500758 655701 631871 719351 1393809 724896 509691 598976 0 965860 0 467949 987164 597490 660785 0 0 658928 571451 645380 307979 0 615933 468836 652526 370318 253953 480682 221020 0 351014 381659 393882 154480 463184 449684 485613 270915 435185 381396 154705 544313 628209 393022 450635 423043 0 713870 0 574469 579189 0 564111 0 0 605329 450023 390251 1156602 0 895167 882517 2322498 1327024 1032041 1459055 1296029 0 978776 1147015 2450023 910438 1084103 1803394 1079731 1983620 1143287 1389486 890933 1034435 2210314 1611044 1071389 1071808 0 2432552 0 1204337 1037744 1090673 610259 0 0 951317 1266344 916487 -AALDNITPQVEVK MGYG000000696_01666;MGYG000002218_02523;MGYG000002438_02205;MGYG000000138_02892 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 478392 0 0 0 0 488995 0 382655 0 0 0 596134 0 0 0 328006 727040 0 0 0 0 0 0 0 0 0 0 559946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1995483 0 0 0 0 0 0 0 0 4082236 0 0 0 0 0 0 0 0 0 0 752203 0 0 0 0 0 0 0 0 0 0 983473 0 0 0 0 584522 0 1352502 0 0 0 936366 0 0 0 708443 1284651 0 0 0 0 0 0 0 0 0 0 803677 0 0 0 0 0 0 0 0 0 0 1239759 0 0 0 0 977325 0 1696127 0 0 0 816294 0 0 0 798446 4717574 0 0 0 0 0 0 0 0 0 0 2024663 0 0 0 0 0 0 0 0 0 0 3784368 0 0 0 0 2689982 0 4337620 0 0 0 2934832 0 0 0 2139617 3849837 0 0 0 0 0 0 0 0 0 0 4612933 0 0 0 0 0 0 -AALDNLEAEMK MGYG000001319_02417 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,4BXZ2@830|Butyrivibrio 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 - 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 551138 0 0 0 0 604911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413894 0 0 0 0 0 0 0 0 0 343576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361601 0 0 0 0 195998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDSGEVTLAK MGYG000002978_00874;MGYG000000693_00169 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CUH0@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 - 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 996259 0 0 0 0 0 0 0 0 0 0 422698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3714478 0 0 0 0 0 0 0 0 0 0 7633659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4881372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDSTR MGYG000000243_02894;MGYG000001546_00564;MGYG000000196_02501;MGYG000002478_00488;MGYG000003493_01559;MGYG000003681_01782;MGYG000003697_01494 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,2FNZ4@200643|Bacteroidia,22VZT@171551|Porphyromonadaceae 0.2857142857142857 976|Bacteroidetes 1.0 C 1.0 Belongs to the LDH MDH superfamily 0.8571428571428571 mdh 1.0 - 1.0 1.1.1.37 1.0 ko:K00024 1.0 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 1.0 R00342,R07136 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ldh_1_C,Ldh_1_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 malate dehydrogenase. malic dehydrogenase. Also oxidizes some other 2-hydroxydicarboxylic acids. (S)-malate + NAD(+) = H(+) + NADH + oxaloacetate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Citrate cycle (TCA cycle);Glyoxylate and dicarboxylate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Cysteine and methionine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1369094 0 0 0 0 0 0 2717054 0 0 0 0 2491708 0 1595708 0 0 3358610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2429282 0 0 0 0 0 0 2255999 0 0 0 0 4983589 0 1512499 0 0 5021013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1790395 0 0 0 0 0 0 262031 0 0 0 0 2526413 0 1802270 0 0 3796191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1242145 0 0 0 0 0 0 5252541 0 0 0 0 1483925 0 844416 0 0 4610796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218864 0 0 0 0 0 0 1428941 0 0 0 0 1191520 0 2219427 0 0 632743 0 0 0 0 0 0 0 0 0 0 -AALDVAGAPAQAR MGYG000002926_00666;MGYG000001675_00817 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 kdd 1.0 - 1.0 1.4.1.11 1.0 ko:K18012 1.0 ko00310,map00310 1.0 - 1.0 R03349 1.0 RC00888 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 0 0 0 152521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 233042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 730832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469552 0 641944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 528187 0 858949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDVNIV(Val->Xle)K MGYG000002438_03065 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0561@1|root,COG0561@2|Bacteria,4PKHD@976|Bacteroidetes,2G0K6@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2113341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALDVNIVK MGYG000002438_03065 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0561@1|root,COG0561@2|Bacteria,4PKHD@976|Bacteroidetes,2G0K6@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581628 0 0 0 0 0 0 0 0 392224 0 318472 0 0 0 0 0 0 0 701835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1013940 0 0 0 0 0 0 0 0 303366 0 856414 0 0 0 0 0 0 0 857585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3121013 0 0 0 0 0 0 0 0 3485479 0 1144004 0 0 0 0 0 0 -AALDVNIVKLDDGTPAANYK MGYG000002438_03065 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0561@1|root,COG0561@2|Bacteria,4PKHD@976|Bacteroidetes,2G0K6@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409824 0 0 0 0 0 0 0 0 387248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 983357 0 0 0 0 0 0 0 0 717248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3345883 0 0 0 0 0 0 0 0 2325090 0 0 0 0 0 0 0 0 -AALDYELLR MGYG000000099_03011 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,248W4@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 274460 0 333516 0 0 0 0 0 190296 0 333866 0 0 234642 354753 0 0 0 0 0 0 0 0 0 0 563462 304227 0 345676 0 0 0 287352 192464 0 0 273447 254837 1359454 0 737657 1209475 0 0 1273403 0 1416992 1475469 847780 822992 0 1298683 1263039 0 0 0 0 1321520 0 0 0 0 0 1176506 1478949 0 1343204 1272861 790924 0 872064 1411562 1231540 1258507 1315078 761702 275714 0 269582 310232 0 0 234457 0 298401 516415 511185 537842 0 352038 321587 0 0 0 0 285995 0 0 0 0 0 333355 207888 0 310573 343464 268637 0 98311 735862 580656 331041 300245 637169 142168 0 143501 135084 0 0 174940 0 112463 0 0 93163 0 189522 180528 0 0 0 0 0 0 0 0 0 0 0 326105 0 0 236449 0 0 145981 276219 0 229298 351668 335597 487732 0 865748 778431 0 0 1145675 0 371223 978703 150899 734856 0 860202 0 0 0 0 0 2355502 0 0 0 0 0 1002145 655181 0 892151 1935353 999045 0 411379 91355 760720 928776 1340173 992369 -AALEA(Ala->Thr)GVNKLADTVR MGYG000000142_02316;MGYG000001338_00216;MGYG000002298_01717;MGYG000000200_01192;MGYG000000184_01883;MGYG000004733_00373;MGYG000000216_01233;MGYG000000171_02643;MGYG000001602_01547 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEAAIAGK MGYG000002171_02571 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002493165|m__MGYG000002171 1.0 COG1256@1|root,COG1256@2|Bacteria,4PKVX@976|Bacteroidetes,2G05N@200643|Bacteroidia,4AWF1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 bacterial-type flagellum assembly 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEAER MGYG000000013_00650;MGYG000004876_03337;MGYG000001345_01115;MGYG000002218_02990;MGYG000001378_02367;MGYG000002438_02820;MGYG000001313_02483;MGYG000002549_00642;MGYG000001783_01305;MGYG000000042_00184;MGYG000002478_04055;MGYG000003351_01292;MGYG000000355_01906;MGYG000003363_02359;MGYG000000098_03753;MGYG000004797_00961;MGYG000003701_01280;MGYG000004479_01379 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia,4AM3W@815|Bacteroidaceae 0.7777777777777778 976|Bacteroidetes 1.0 C 1.0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 none 1.0 0 0 1328250 0 0 1259674 0 0 0 0 0 0 0 0 0 2552926 0 0 0 0 0 1453473 0 2440307 0 0 0 0 1834488 1871546 2125368 0 1808239 0 0 1976868 0 1876870 0 0 2908293 0 0 1953479 0 0 0 0 2654606 0 0 0 0 0 0 0 0 0 0 2143478 0 1412410 0 0 0 0 0 1773685 1196503 0 2383051 0 0 2031089 0 1298617 0 0 1356392 0 0 1214525 0 0 0 0 1238359 0 0 0 0 1459917 0 0 0 0 0 0 0 1216314 0 0 0 0 1159206 0 0 0 1040027 0 0 1277853 0 1335112 0 0 543189 0 0 497772 0 0 0 0 0 0 0 0 0 737029 0 0 0 0 0 0 0 750178 0 0 0 0 490959 0 635616 0 536082 0 0 735757 0 449978 0 0 0 0 0 1797502 0 0 0 0 0 0 0 0 0 2711135 0 0 0 0 0 1113824 0 0 0 0 0 0 0 2367730 0 0 1078095 0 0 0 0 0 -AALEAERYLSSNC(Carbamidomethyl)LL MGYG000004876_03337 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__|m__MGYG000004876 1.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia,4AM3W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4415514 0 0 0 0 270206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175617 0 0 0 0 84303 0 0 0 0 183659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEAFR MGYG000002065_00912;MGYG000004746_00558;MGYG000003266_00145;MGYG000001718_01732 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CV00@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9 1.0 ko:K08483 1.0 ko02060,map02060 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--protein phosphotransferase. sugar--PEP phosphotransferase enzyme I. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 none 1.0 0 2861338 0 0 0 0 0 0 0 0 0 0 1864525 0 0 0 886802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 963336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746266 0 0 0 0 0 0 0 0 0 0 708695 0 0 0 2413121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3314841 0 0 0 2390590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 687242 0 0 0 0 0 0 0 0 0 0 947593 0 0 0 422822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEAGDQAVIDQITAK MGYG000000074_01748 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1271@1|root,COG1271@2|Bacteria,4NG7U@976|Bacteroidetes,2FMV6@200643|Bacteroidia,22UC3@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Cytochrome bd terminal oxidase subunit I 1.0 cydA 1.0 - 1.0 1.10.3.14 1.0 ko:K00425 1.0 ko00190,ko01100,ko02020,map00190,map01100,map02020 1.0 M00153 1.0 R11325 1.0 RC00061 1.0 ko00000,ko00001,ko00002,ko01000 1.0 3.D.4.3 1.0 - 1.0 - 1.0 Cyt_bd_oxida_I 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ubiquinol oxidase (electrogenic, proton-motive force generating). cytochrome bd-I oxidase. This terminal oxidase enzyme is unable to pump protons but generates a proton motive force by transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water.-!-The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) is 1.-!-The bd-I oxidase from the bacterium Escherichia coli is the predominant respiratory oxygen reductase that functions under microaerophilic conditions in that organism. cf. EC 7.1.1.3.-!-Formerly EC 1.10.3.14. 2 a ubiquinol + 4 H(+)(in) + O2(in) = 2 a ubiquinone + 4 H(+)(out) + 2 H2O(in). 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEAGVDKLANTVR MGYG000003702_00464;MGYG000000404_00409 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,27I73@186928|unclassified Lachnospiraceae 0.5 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 946818 568658 0 1023962 0 0 1135461 0 576179 1568446 629822 733554 0 0 614844 0 261719 0 0 0 0 266916 0 0 0 0 366452 739876 847077 0 0 181012 0 555129 0 0 554611 0 0 416810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 214594 115191 0 160192 0 0 360005 0 198839 194874 327131 351680 0 0 264950 0 384474 0 0 0 0 487804 0 0 0 0 628145 269595 299789 0 0 402374 0 324657 0 0 107057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518497 0 0 0 0 176099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408454 0 0 0 0 0 0 0 0 0 0 0 0 343004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEAGVN(Deamidated)KLANTVR MGYG000000135_03500 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Murimonas|s__Murimonas intestini|m__MGYG000000135 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 541968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEAGVNK MGYG000000142_02316;MGYG000002298_01717;MGYG000000200_01192;MGYG000000119_02608;MGYG000000171_02643;MGYG000000135_03500;MGYG000000268_00624;MGYG000001338_00216;MGYG000002312_00711;MGYG000000184_01883;MGYG000004733_00373;MGYG000000216_01233;MGYG000001602_01547 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 0.8461538461538461 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 3685659 7729937 5160105 1921319 6653888 6073294 1903432 4610712 2722525 3509025 6763879 5060618 6029066 2905826 3997260 5541750 3247561 7288311 3196872 4588754 3709378 7458694 3757257 2485220 3837891 2777680 2509386 5356095 3262344 2667917 3841281 8386702 3778904 3334460 3687755 2469811 2461231 4965552 2176158 19401696 2375969 1450588 4385384 2674752 2612646 2479018 2082986 2080615 3489454 1303449 3153441 1680569 1551797 1760827 2404255 6231816 1777098 2241879 1291629 2314256 3319994 3712117 2028290 1696605 2452584 4996742 3157636 1827059 18556581 7472446 2658767 1532294 2673780 2395682 2306766 3076637 4477452 19582604 6078061 3874922 3195160 7973657 3629296 5992450 3933746 5404072 4758449 4306510 5377593 4881174 6111418 6624880 6477948 2447331 5315926 5781408 5375692 12396012 3881455 5947499 5280017 5326223 6398636 4779420 4764760 6436787 8718411 16579702 8251288 7019563 5731669 3380678 2741001 6162809 2253362 9910010 5284950 2402576 7277739 3107275 2579346 2808268 2472303 4353737 5417172 2825167 4789727 2029175 2002261 5757164 3499154 3399919 1395399 1764838 1959816 4551308 1567589 3948495 1710349 1383715 2706750 4006000 10051567 2510496 17378346 7833316 6586541 1695234 2284097 1662071 1935675 7079378 3249475 14235509 10488857 3998176 4568965 4441521 3142747 3588548 2663201 3647967 4926914 3111757 4888277 3743001 3247030 4786240 2531083 2350972 3164874 1534182 2146226 3774091 4824671 4857017 2831366 3274527 3171292 4275248 2416356 2444781 12442574 14687508 14283133 3504315 3787077 4644980 2060686 6974482 -AALEAGVNKLADTVR MGYG000000142_02316;MGYG000001338_00216;MGYG000002298_01717;MGYG000000200_01192;MGYG000000184_01883;MGYG000004733_00373;MGYG000000216_01233;MGYG000000171_02643;MGYG000001602_01547 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 596433 0 477452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 425341 0 0 0 349715 295526 0 0 0 785756 1273135 507630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 717819 0 0 0 100687 0 0 0 0 0 0 0 0 0 0 1049266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322223 0 0 0 0 100276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359304 0 0 0 0 0 0 0 0 0 292352 0 0 0 91603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191074 337003 223162 0 0 0 0 105552 -AALEAGVNQLADTVR MGYG000000217_01904;MGYG000003486_00745;MGYG000000146_01484 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,27I73@186928|unclassified Lachnospiraceae 0.6666666666666666 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2202079 0 0 0 0 2236833 0 0 0 0 2618727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 787221 0 0 0 0 491159 0 0 0 0 694876 0 280769 0 0 0 0 709183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1631812 0 0 0 0 952135 0 0 0 0 1551198 0 919765 0 0 0 0 1071671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519372 0 0 0 0 0 0 0 0 0 754487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424340 0 0 0 0 0 0 0 0 0 1020105 0 535382 0 0 0 0 335599 0 0 0 -AALEAIYHAGK MGYG000000198_04353 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG1527@1|root,COG1527@2|Bacteria,1U6WZ@1239|Firmicutes,249XD@186801|Clostridia,21YEI@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Archaeal vacuolar-type H -ATPase subunit C 1.0 ntpC 1.0 - 1.0 - 1.0 ko:K02119 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 DUF2764,vATP-synt_AC39 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEAR MGYG000002040_00491;MGYG000001315_00699 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3WGEY@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 G 0.5 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain 0.5 pgcA 0.5 - 0.5 5.4.2.2,5.4.2.8 0.5 ko:K01835,ko:K01840 0.5 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 0.5 M00114,M00549 0.5 R00959,R01057,R01818,R08639 0.5 RC00408 0.5 ko00000,ko00001,ko00002,ko01000 0.5 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 0.5 - 1.0 - 1.0 - 1.0 GT2 0.5 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). | phosphomannomutase. phosphoglucose mutase. | phosphomannose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. | alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. | alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 0.5 0.5 0.5 0.5 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Microbial metabolism in diverse environments;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Streptomycin biosynthesis;Galactose metabolism;Purine metabolism;Biosynthesis of secondary metabolites 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1123795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEATTNALK MGYG000002293_00760 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 428092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446601 0 280885 0 0 0 370112 0 0 0 0 0 0 0 0 0 257843 0 0 0 0 0 130008 0 0 0 0 0 0 0 0 0 0 0 118938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305585 0 0 0 0 0 0 0 0 0 0 0 619378 0 0 0 372418 388768 369854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2242308 0 0 2026311 0 0 0 0 0 0 0 0 0 0 0 5754299 0 0 0 1374427 6172323 1417366 0 0 0 2263212 0 0 0 0 1997786 0 0 0 0 982710 0 0 243198 0 0 242896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338797 0 114845 0 0 0 0 0 0 0 0 0 0 0 0 0 144906 -AALEATTNALKEA MGYG000002293_00760 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 649419 0 0 0 0 360918 0 0 0 0 258016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1840009 0 0 0 0 2162047 0 0 0 0 1310635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEC(Carbamidomethyl)GVNK MGYG000004735_02784 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,27I73@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 144882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1283891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7711072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEDALELGR MGYG000001315_02988 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,268A2@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Peptidase family M20/M25/M40 1.0 - 1.0 - 1.0 3.5.1.18 1.0 ko:K01439 1.0 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 1.0 M00016 1.0 R02734 1.0 RC00064,RC00090 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinyl-diaminopimelate desuccinylase. - - H2O + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6- diaminoheptanedioate + succinate. 1.0 1.0 1.0 1.0 Lysine biosynthesis;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEDKDSVFYYYQK MGYG000004296_00733 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Ruminococcus_A|s__Ruminococcus_A faecicola|m__MGYG000004296 1.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,25UWG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 malL 1.0 - 1.0 3.2.1.1,3.2.1.10 1.0 ko:K01176,ko:K01182 1.0 ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973 1.0 - 1.0 R00801,R01718,R01791,R02108,R02112,R06199,R11262 1.0 RC00028,RC00059,RC00077,RC00451 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH13 1.0 - 1.0 Alpha-amylase,DUF3459,Glyco_hydro_42C,Malt_amylase_C 1.0 5.4.99.11|3.2.1.10|3.2.1.20|3.2.1.70|3.2.1.-|2.4.1.- 1.0 GH13_31 1.0 GH13 1.0 GH13_31 1.0 alpha-amylase. | oligo-1,6-glucosidase. glycogenase. | sucrase-isomaltase. Acts on starch, glycogen and related polysaccharides and oligosaccharides in a random manner; reducing groups are liberated in the alpha-configuration.-!-The term 'alpha' relates to the initial anomeric configuration of the free sugar group released and not to the configuration of the linkage hydrolyzed. | This enzyme, like EC 3.2.1.33, can release an alpha-1->6-linked glucose, whereas the shortest chain that can be released by EC 3.2.1.41, EC 3.2.1.142 and EC 3.2.1.68 is maltose.-!-It also hydrolyzes isomaltulose (palatinose), isomaltotriose and panose, but has no action on glycogen or phosphorylase limit dextrin.-!-The enzyme from intestinal mucosa is a single polypeptide chain that also catalyzes the reaction of EC 3.2.1.48.-!-Differs from EC 3.2.1.33 in its preference for short-chain substrates and in its not requiring the 6-glucosylated residue to be at a branch point, i.e. linked at both C-1 and C-4. Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units. | Hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Carbohydrate digestion and absorption;Starch and sucrose metabolism 1.0 none 1.0 0 601335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1295181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1544099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEEAEHAAK MGYG000000099_03581 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,2681B@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 476160 0 0 431936 0 0 0 0 664333 0 0 0 490106 0 474061 0 0 616554 0 458653 0 0 841959 0 547904 489861 503609 663996 266347 0 0 0 0 491248 599641 477859 580437 0 2025548 0 0 1698936 0 0 0 0 1763372 0 0 0 941896 0 2017587 0 0 153804 0 1749540 0 0 379041 0 1397627 1654609 1608929 273971 1790005 0 0 0 0 1839638 1347355 1708291 1655800 0 708231 0 0 536813 0 0 0 0 457824 0 0 0 372777 0 513699 0 0 487304 0 377774 0 0 489228 0 543773 503224 548786 494263 534061 0 0 0 0 538017 360961 360284 400363 0 507249 0 0 377878 0 0 0 0 451087 0 0 0 216146 0 520396 0 0 253552 0 430896 0 0 452351 0 316522 443852 317685 629416 465730 0 0 0 0 574268 492909 384019 515240 0 431678 0 0 896915 0 0 0 0 416766 0 0 0 572347 0 500758 0 0 1825272 0 427608 0 0 2046891 0 340015 486866 626427 1756001 5713384 0 0 0 0 437053 805943 572512 457607 0 -AALEEAR MGYG000002274_01167;MGYG000004701_01171;MGYG000000099_03676;MGYG000000213_00501;MGYG000001783_00694;MGYG000001300_00868;MGYG000000185_00200 domain d__Bacteria 1.0 COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia,3WHZ5@541000|Ruminococcaceae 0.2857142857142857 186801|Clostridia 0.7142857142857143 T 0.2857142857142857 GHKL domain 0.2857142857142857 - 0.5714285714285714 - 0.8571428571428571 - 0.5714285714285714 - 0.42857142857142855 - 0.5714285714285714 - 0.7142857142857143 - 0.7142857142857143 - 0.7142857142857143 - 0.42857142857142855 - 1.0 - 0.8571428571428571 - 1.0 HATPase_c_5 0.2857142857142857 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - - - - 0.5714285714285714 0.5714285714285714 0.5714285714285714 0.5714285714285714 0.5714285714285714 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1911139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEEGIVPGGGVAYIR MGYG000004876_02137;MGYG000002478_00380;MGYG000003363_02977;MGYG000004763_01826;MGYG000000243_00634 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16107744 0 0 0 0 0 0 0 0 0 0 0 0 0 6390357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6980676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2309748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEFAVAASALK MGYG000002281_02000;MGYG000000196_03698;MGYG000000198_01239;MGYG000000179_03806;MGYG000000243_01648;MGYG000002478_03488;MGYG000000278_03485;MGYG000001688_01694;MGYG000001619_01935;MGYG000000242_02691;MGYG000001065_01869;MGYG000001378_01448;MGYG000001531_02708;MGYG000004797_00251;MGYG000002171_00496 domain d__Bacteria 1.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,21YXD@1506553|Lachnoclostridium 0.5333333333333333 186801|Clostridia 0.5333333333333333 G 1.0 pfkB family carbohydrate kinase 0.5333333333333333 - 0.5333333333333333 - 1.0 2.7.1.45 0.5333333333333333 ko:K00874 0.5333333333333333 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 0.5333333333333333 M00061,M00308,M00631 0.5333333333333333 R01541 0.5333333333333333 RC00002,RC00017 0.5333333333333333 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 0.5333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 2-dehydro-3-deoxygluconokinase. KDG kinase. The enzyme shows no activity with 2-dehydro-3-deoxy-D-galactonate. cf. EC 2.7.1.178. 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D- gluconate + ADP + H(+). 0.5333333333333333 0.5333333333333333 0.5333333333333333 0.5333333333333333 Pentose phosphate pathway;Metabolic pathways;Carbon metabolism;Microbial metabolism in diverse environments 0.5333333333333333 none 1.0 187895 0 227300 340659 0 143072 151067 175872 312808 318071 0 331385 0 171249 152017 108262 232518 0 0 287631 0 94685 0 162026 0 214065 0 0 0 199573 0 0 0 0 0 0 229626 0 337824 0 0 519313 0 185268 334799 305659 331840 483388 0 160187 0 313205 330527 215600 123011 1019579 0 347285 0 99369 889167 325777 0 159874 0 445883 0 212687 0 0 0 0 0 0 350428 181204 780392 0 111028 726018 0 466407 674206 424196 522811 578603 0 517604 0 669111 707899 500466 445665 861752 0 700744 0 614145 788258 311878 0 614725 0 854028 0 749317 0 0 660227 0 0 0 436273 452067 517681 0 360449 519405 0 582285 243121 755238 508755 638170 0 198261 0 772661 666884 410894 528955 480228 0 1123618 0 410187 459914 0 0 458098 0 342516 0 572113 0 0 97299 0 0 0 390513 0 1271994 0 857706 1248618 0 722172 1285939 1053307 1080124 1024861 0 766634 0 1845846 1440546 512657 1090584 1225134 0 1035139 0 771432 2102933 688512 0 1148275 0 3214325 0 1024042 0 0 813547 0 0 0 1111905 849262 -AALEIIEKGPYK MGYG000001415_00853 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,2FM6J@200643|Bacteroidia,4AMTF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_2,SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 821068 608774 784891 0 978720 1161158 0 0 0 0 855423 987824 0 0 0 867513 856808 1163674 703360 0 1000692 940143 0 1496347 0 0 0 0 0 0 1571781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41540 0 0 0 0 43608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139296 227852 0 228684 124578 0 0 0 0 165874 76292 0 0 0 131350 71204 230707 55595 0 168657 115809 0 171786 0 0 0 0 0 0 75018 0 0 0 0 0 0 0 0 212244 193828 0 137997 147101 0 0 0 0 212556 256920 0 0 0 216652 189870 77626 105373 0 0 180096 0 235406 0 0 0 0 0 0 497281 0 0 0 0 0 0 0 64966 0 0 0 86487 82440 0 0 0 0 104974 108644 0 0 0 176284 76912 78064 0 0 125578 88025 0 79895 0 0 0 0 0 0 188848 0 0 0 0 -AALEIMK MGYG000001415_00308 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes,2FUJN@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG16623 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Hc1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1451514 1415242 1039735 1267191 0 1233900 1427118 1557833 0 1274070 0 1277258 0 1603184 0 871722 1224291 0 950353 0 1521649 1196494 0 1509350 1319222 1464488 0 0 1301702 1081637 957284 0 1123425 2036292 1211525 0 1503146 1036187 346880 0 437891 376222 0 446395 316059 352646 0 613581 0 357619 0 448900 0 483386 363208 0 630364 0 338251 143372 0 368956 0 81664 0 0 321680 338672 213799 0 622597 0 294564 0 369146 258813 352959 115992 392860 417531 0 601242 239404 310623 0 410691 0 199400 0 476075 0 92029 257775 0 317576 0 400517 691103 0 742708 627959 331958 0 0 277086 321045 766257 0 316297 375028 0 0 555517 382961 534679 566369 236281 307697 0 393776 457709 248012 0 360152 0 471495 0 452193 0 504042 460397 0 498580 0 465222 325091 0 336157 308223 299908 0 0 267007 772653 333819 0 171287 801457 674044 0 400792 668370 425221 0 97050 420373 0 0 547542 0 0 0 0 183406 0 106735 0 67483 292790 0 394519 0 0 172062 0 0 210252 0 0 0 621000 298179 0 0 140257 532867 0 0 369072 0 -AALEISQLD MGYG000002494_04127 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3WV6W@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 K 1.0 Transcriptional regulator PadR-like family 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3813423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4259242 0 2722010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEKGVNQLADTVK MGYG000004558_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__|m__MGYG000004558 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 126838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEKKDYLAK MGYG000000271_02509;MGYG000004271_00777 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALELAEQR MGYG000001708_01490;MGYG000003360_03404;MGYG000002323_00410;MGYG000002494_02445;MGYG000001465_00016;MGYG000002534_00416;MGYG000003390_02531;MGYG000002535_00001;MGYG000002366_00460;MGYG000001466_00766;MGYG000000235_04517;MGYG000002515_03179;MGYG000002507_04205;MGYG000002477_00163;MGYG000002506_02937;MGYG000000107_05334;MGYG000000093_01116 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,3XNVS@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 2337857 2205743 1916139 1958095 1633793 3709488 0 2818455 2196827 0 1084324 0 613531 2147776 1916503 1129562 2115700 0 2091473 2068173 0 3843303 0 3862776 0 1900647 0 0 0 0 1673545 2090143 0 0 2399328 2004717 2209528 0 5143957 5319969 5297233 4273862 3458689 8337264 4560557 4451690 4954582 6248409 1792585 4270769 2467542 5692253 4558984 3279524 5353237 0 7098837 4111080 6486008 8074018 0 5929341 5004308 4943788 3750811 0 5907432 5247235 1977371 4169584 5814507 4513053 4632446 5537980 4390603 5581157 2753198 3131944 3383558 2788417 3462010 5192204 3630471 3645820 2429367 3392978 2291826 1994281 2073976 3756684 2451429 2199389 3227781 0 2781898 3771812 3320456 5281714 0 5198888 3061076 2565158 1841107 0 2867013 2137557 2994046 3382742 3177907 3465114 1707129 3070699 2481486 3248868 3318417 2793916 3432878 2146240 2494664 3386447 3166298 3542231 2039037 3553115 1594141 2188937 2144312 2324997 2599055 2480593 1795960 0 2388397 2240356 3459811 3701176 0 2859615 3135292 2598947 2469342 0 2230562 1974587 1983902 2565645 3490436 3287088 3626183 3639368 2273864 2423075 233289 0 299350 0 0 459219 0 0 0 319784 0 0 0 219445 0 0 0 0 237803 436317 0 187372 0 439845 231161 155282 0 0 200699 0 0 0 377960 0 0 0 0 0 -AALELMK MGYG000001415_00308 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes,2FUJN@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG16623 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Hc1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1340676 0 0 0 0 0 0 0 0 0 0 0 1754208 0 0 0 0 0 0 0 0 1666472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 615214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168556 0 0 0 0 0 0 0 0 0 0 0 -AALELSK MGYG000001302.1_01633;MGYG000003469_00939 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 S 1.0 Histone H1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Hc1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1165820 1174452 0 0 0 1168870 0 0 0 0 1136251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456962 0 0 0 1068868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1506635 1580827 0 0 0 1328061 0 0 0 0 1149908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1091585 825891 0 0 0 134260 0 0 0 0 1735969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3049002 2374353 0 0 0 2628526 0 0 0 0 2113926 0 0 0 0 0 0 0 0 0 0 -AALEN(Asn->Ser)GVNQLANTVR MGYG000000133_00304 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 507296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1027845 0 0 0 0 0 1126373 0 1100153 0 0 0 0 0 0 0 0 957291 0 0 0 0 0 0 0 0 0 0 1129867 0 -AALEN(Deamidated)GVNQLANTVR MGYG000000133_00304 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 233907 204217 478778 278674 515472 758606 564440 325643 613148 0 522037 374946 339848 844983 604326 354113 358565 0 792985 543885 315713 1066972 0 664125 705332 743132 775867 0 778818 405931 405423 292138 373281 1072859 642634 804222 314282 419356 485424 112890 756950 307125 634562 487252 322302 0 255298 0 509567 358177 729671 282953 636164 487878 319404 0 234664 406799 410576 537801 0 358424 339739 227978 346433 0 0 220653 310049 453698 249293 276405 249168 399355 158525 366786 268385 510729 1056276 0 519282 1091513 667150 302247 261247 0 507551 771844 755034 294550 307124 735280 556032 0 317876 488244 185634 587696 0 260014 410483 323003 401949 0 376403 405717 372601 571244 601414 192771 436294 275450 400452 1236276 685501 251749 648674 847148 436303 896837 468049 1183187 704330 0 492785 469902 339187 645689 610199 335873 423304 0 823799 432820 501826 541470 0 412737 1008548 912469 1482200 0 335237 735726 310121 356455 811611 467247 774165 1000947 644490 573531 7501999 8443837 9421550 11992006 1125681 4195279 12265720 6308452 4777892 0 9687598 7178386 4961703 13684707 1725936 8541995 6608321 0 7635370 2055692 10413807 6145028 0 5227588 7413227 6024337 8706082 0 10965594 1734300 5617947 9793038 17974294 7653833 5321197 9372791 5423424 5401337 -AALENGVN(Deamidated)QLANTVR MGYG000000133_00304 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 694267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6486414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALENGVNQLANTVR MGYG000000133_00304 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 66403 0 0 98059 0 0 0 0 93567 369731 0 728682 0 0 539797 0 0 186722 0 0 0 0 0 0 0 0 437165 253318 293936 0 0 0 0 205008 0 0 0 129761 193009 126356 105336 0 0 0 0 0 82034 0 88055 0 69703 0 84270 0 0 0 0 98244 0 231966 82255 0 0 0 58603 86501 181273 0 0 135817 0 107058 0 0 710976 0 426960 0 0 290278 0 145820 0 604753 96555 0 0 0 194622 0 0 0 0 0 0 145550 0 0 0 0 0 0 581615 0 118087 0 0 0 0 0 0 0 0 0 0 0 0 0 561571 484351 0 0 0 454574 332076 500593 195764 0 0 0 0 0 0 0 0 381635 0 0 0 0 520231 0 0 0 0 0 0 424428 8179976 9584824 6267873 14499588 679990 3610782 9977823 5693563 4109463 8884965 10615200 5189810 5700706 14310969 6529786 8281083 7711180 0 6066354 2209716 9473178 7776191 0 6501980 7792637 5589002 10518191 0 11583436 1408438 6644783 12206871 17057259 8168467 5159916 8932291 4745879 4782831 -AALENQIK MGYG000000271_00657 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 - 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEPIEAEMTSLNKR MGYG000004797_01140 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia,4ANV3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 ATPase histidine kinase DNA gyrase B HSP90 domain protein 1.0 htpG 1.0 - 1.0 - 1.0 ko:K04079 1.0 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HATPase_c_3,HSP90 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Estrogen signaling pathway;Antigen processing and presentation;Necroptosis;Prostate cancer;NOD-like receptor signaling pathway;Plant-pathogen interaction;Protein processing in endoplasmic reticulum;Th17 cell differentiation;Progesterone-mediated oocyte maturation;Fluid shear stress and atherosclerosis;Pathways in cancer;IL-17 signaling pathway;PI3K-Akt signaling pathway 1.0 none 1.0 0 0 1684381 2246079 1963154 0 1733668 1287235 0 1738644 0 1570547 1484664 1289473 1056809 1460670 1752440 1540770 1805522 1326346 1472421 1266700 2168185 2009702 1553398 1748540 2363326 2422569 2148029 1308079 2537275 1672838 1759346 0 0 1842228 0 1660429 1160118 0 1623021 1501499 1414800 1593567 1124649 1379651 1229919 1816715 0 0 1357948 1617616 1865812 1173240 3717804 0 1675252 1665215 1658414 2434969 2035073 1388323 1785666 1364937 1282551 1537041 1696705 1250767 1311858 1693281 1497884 0 0 1197358 1276732 1251998 680413 0 660970 526841 944115 860614 891314 584477 677345 598220 0 835584 960798 639261 705592 718208 952533 1974191 763133 685598 423423 675292 1926389 609272 615468 707224 699325 1651076 629640 375179 776126 387168 694003 0 0 580808 585087 811329 65558 0 208631 90964 197859 72196 224089 180878 132739 110575 0 173120 161310 299114 125741 84724 118909 0 117906 67089 221187 219307 0 0 191464 73503 112212 0 83154 0 0 445436 176634 0 0 0 65040 0 576132 0 657918 682195 1093042 786018 612257 830651 673607 319707 0 513225 1182252 461038 595529 853140 780164 1526107 766875 867225 406874 673273 1439415 789441 686770 884040 1011581 1343561 871651 598329 662542 637806 473128 0 0 720071 735218 616651 -AALEPIESEMANLNNR MGYG000000243_01589 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia,4ANV3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 ATPase histidine kinase DNA gyrase B HSP90 domain protein 1.0 htpG 1.0 - 1.0 - 1.0 ko:K04079 1.0 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HATPase_c_3,HSP90 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Estrogen signaling pathway;Antigen processing and presentation;Necroptosis;Prostate cancer;NOD-like receptor signaling pathway;Plant-pathogen interaction;Protein processing in endoplasmic reticulum;Th17 cell differentiation;Progesterone-mediated oocyte maturation;Fluid shear stress and atherosclerosis;Pathways in cancer;IL-17 signaling pathway;PI3K-Akt signaling pathway 1.0 none 1.0 0 0 863177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 624371 0 0 0 0 553800 0 0 0 0 449333 0 0 0 0 897007 0 0 0 0 634441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366176 0 0 0 0 531639 0 0 0 0 0 0 0 0 0 0 0 0 579790 0 0 0 0 0 0 0 0 0 0 0 0 0 0 786699 0 0 0 0 468657 0 0 0 0 307532 0 0 0 0 710500 0 0 0 0 533486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250721 0 0 0 0 0 0 0 0 0 197745 0 0 0 0 0 0 0 0 0 0 0 0 180082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190629 0 0 0 0 283948 -AALEPIET(Thr->Ala)EMTSLNKR MGYG000002478_03790 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia,4ANV3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 ATPase histidine kinase DNA gyrase B HSP90 domain protein 1.0 htpG 1.0 - 1.0 - 1.0 ko:K04079 1.0 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HATPase_c_3,HSP90 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Estrogen signaling pathway;Antigen processing and presentation;Necroptosis;Prostate cancer;NOD-like receptor signaling pathway;Plant-pathogen interaction;Protein processing in endoplasmic reticulum;Th17 cell differentiation;Progesterone-mediated oocyte maturation;Fluid shear stress and atherosclerosis;Pathways in cancer;IL-17 signaling pathway;PI3K-Akt signaling pathway 1.0 none 1.0 1559825 0 0 0 0 1524178 0 0 1955581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1438000 0 0 1139463 0 0 0 0 0 0 0 0 0 1598069 0 0 0 0 0 1514761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190434 0 0 0 0 0 0 0 156012 0 0 0 0 0 0 0 0 0 0 0 0 71594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEQGV(Val->Ser)NK MGYG000000164_00892 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,27I73@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 1899384 0 0 0 0 0 0 0 1404149 3238049 0 0 0 0 2872995 0 0 0 0 3096662 0 1562767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1230585 0 0 0 0 0 0 0 2083661 2674743 0 0 0 0 6135073 0 0 0 0 5352843 0 2173397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 539885 0 0 0 0 0 0 0 436728 1102302 0 0 0 0 0 0 0 0 0 1133906 0 535059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194904 965777 0 0 0 0 433986 0 0 0 0 532433 0 0 0 0 0 0 0 0 0 0 -AALEQGVNK MGYG000000164_00892 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,27I73@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 5944543 0 0 0 3053440 2058754 6771081 5034750 5975450 5630879 1842532 0 5760653 4572672 5601408 0 2336993 0 4338692 0 8118653 3803162 0 1675241 7359477 4671494 3917689 0 4519436 3682607 0 0 0 4338789 4582886 5664245 4873799 0 187648 0 0 0 1094053 476146 491127 281282 368351 457084 524367 0 474526 301141 220901 0 505741 0 503804 0 627576 419837 0 506999 241451 318642 289613 0 684236 603044 0 0 0 386016 535986 340265 0 0 373379 0 0 0 0 0 518117 576918 0 275093 0 0 565465 338372 547552 0 0 0 1126058 0 482803 0 0 0 769096 242253 294816 0 0 277071 0 0 0 329145 776101 260874 265747 0 937261 0 0 0 969222 789289 0 0 875272 1067769 194112 0 668478 951431 0 0 749277 0 940860 0 0 1585453 0 2493695 575713 0 0 0 1750141 214447 0 0 0 584432 165911 0 239228 0 221621 0 0 0 0 98278 0 255920 192311 0 0 0 295873 799413 0 0 0 0 246900 0 236689 127673 0 0 562233 263203 232522 0 0 253317 0 0 0 244763 373214 577578 147788 0 -AALERGVNQLADTVR MGYG000002835_00808 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter sp900543115|m__MGYG000002835 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,27I73@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 798171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALESGVNQLANTVR MGYG000000301_00959;MGYG000000806_01492;MGYG000002966_01600;MGYG000003012_02207 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 1215714 0 64015 426063 0 0 215415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271427 156225 278380 0 0 0 377080 206643 402815 296942 482325 0 0 0 0 0 0 0 0 0 0 1063940 1115630 0 1328810 0 0 0 126913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83291 79337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1024923 1498604 1198534 1282092 0 1231923 2115695 1303483 0 2176092 2091383 0 733856 1972730 0 1108736 0 0 1483756 0 1317374 1987405 0 1910820 1215478 0 1828941 0 2076430 516215 1386570 2016197 1980139 1605960 1252015 0 0 1243888 -AALESTLAAITESLK MGYG000003372_03358;MGYG000002494_02496;MGYG000002515_03637;MGYG000002535_04014;MGYG000002477_01000;MGYG000002506_03710;MGYG000002534_04602 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,3XPW4@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupA 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006323,GO:0006351,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:1990104,GO:1990178,GO:2001141 1.0 - 1.0 ko:K03530,ko:K05787 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 574894 0 470412 0 0 167244 414561 0 381275 0 0 0 0 0 968570 0 410072 0 0 0 0 9832977 0 109966 0 127440 0 0 0 0 0 420387 354438 10971154 0 0 668020 319409 17077201 0 0 0 0 12233989 70349600 0 14899469 0 0 0 0 0 54745225 0 89466696 0 0 0 0 14077772 0 125006746 0 330452 0 0 0 0 0 27905187 436120 12756794 0 0 29549197 45371803 1219681 0 1756954 0 0 17040236 6433458 0 0 0 0 0 0 0 0 0 403644 0 0 0 0 724937 0 0 0 0 0 0 0 0 0 0 0 115907 0 0 0 0 1092255 0 0 0 0 0 0 0 8558344 0 0 0 0 0 4949463 0 0 0 0 0 0 0 0 5562030 0 4906365 0 0 0 0 0 10594939 0 13883784 0 0 7482466 6080537 0 0 1601788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3602639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALESTLAAITESLKEGDAVQLVGFGTFK MGYG000003372_03358;MGYG000002494_02496;MGYG000002506_03710 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,3XPW4@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupA 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006323,GO:0006351,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:1990104,GO:1990178,GO:2001141 1.0 - 1.0 ko:K03530,ko:K05787 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 5372714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 26974770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6475086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4554182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALETAVANVESAK MGYG000002478_01778;MGYG000000243_02508 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,2FN62@200643|Bacteroidia,4AP66@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family 1.0 - 1.0 - 1.0 - 1.0 ko:K03585 1.0 ko01501,ko01503,map01501,map01503 1.0 M00646,M00647,M00699,M00718 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 1.0 2.A.6.2,8.A.1.6 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cationic antimicrobial peptide (CAMP) resistance;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1761377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1102700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALETGVNK MGYG000000212_00038 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599910 0 2603888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8675022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2423335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3309299 0 0 0 0 0 0 0 0 0 -AALETGVNKLADTVR MGYG000000212_00038 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALETQIK MGYG000004271_00888 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 - 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2278146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1729904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALETVK MGYG000000243_01974 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3325777 0 0 0 0 6308235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3075642 0 0 0 0 0 0 0 0 0 1635795 0 0 0 0 0 0 0 0 0 0 -AALEV(Val->Thr)GVNKLADTVR MGYG000002202_00450 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Massilistercora|s__Massilistercora timonensis|m__MGYG000002202 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,21YIV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALEVK MGYG000001623_01332;MGYG000002528_02478;MGYG000004594_00959;MGYG000004667_00970;MGYG000001615_00145;MGYG000000233_02503;MGYG000000325_02351;MGYG000002098_00511;MGYG000004087_01282;MGYG000002590_00564;MGYG000004891_00190;MGYG000000378_00784;MGYG000002247_01703;MGYG000000179_00100;MGYG000000074_00389;MGYG000001564_02842;MGYG000000028_00797;MGYG000000217_00686;MGYG000002212_01829;MGYG000001577_00663;MGYG000004380_01725;MGYG000000198_00250;MGYG000000118_00274;MGYG000001423_03022;MGYG000002139_00077;MGYG000003291_00558;MGYG000000312_02404;MGYG000000121_02531;MGYG000001754_01214;MGYG000001338_02151;MGYG000001646_00500;MGYG000000184_00575;MGYG000003486_02360;MGYG000004879_02866;MGYG000000202_02337;MGYG000002082_01062;MGYG000000087_02439 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,21XUV@1506553|Lachnoclostridium 0.1891891891891892 186801|Clostridia 0.9459459459459459 G 0.918918918918919 Belongs to the PEP-utilizing enzyme family 0.7027027027027027 ppdK 0.918918918918919 - 0.9459459459459459 2.7.9.1 0.918918918918919 ko:K01006 0.918918918918919 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.918918918918919 M00169,M00171,M00172,M00173 0.918918918918919 R00206 0.918918918918919 RC00002,RC00015 0.918918918918919 ko00000,ko00001,ko00002,ko01000 0.918918918918919 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.918918918918919 - 1.0 - 1.0 - 1.0 GT1 0.8918918918918919 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.918918918918919 0.918918918918919 0.918918918918919 0.918918918918919 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 0.918918918918919 none 1.0 0 2448713 1075654 924437 3170530 863584 0 0 0 0 1856956 1263285 2762666 0 0 2330746 0 0 0 1816210 0 1218899 3094312 1258963 920299 0 1178458 3362842 750027 0 0 0 917961 0 0 0 0 1389487 0 7731515 2930426 1533923 2585713 2877244 0 0 0 0 0 0 3337023 0 0 2833560 0 2659923 2542523 2027121 0 0 2120687 2768642 1941737 0 0 0 2381358 0 0 0 0 0 0 0 0 0 0 10143358 1255398 2393586 1243542 1976618 0 0 0 0 0 1863714 1902505 0 0 2713854 0 275561 2432960 0 0 0 1670137 0 3068078 0 1942743 2434452 2236913 0 0 0 0 0 0 0 0 0 0 0 2260378 1531974 3057656 1150389 0 0 0 0 3300331 2041349 1593268 0 0 0 0 1129836 2484634 1655558 0 0 246074 2849415 667642 0 0 0 1695951 0 0 0 0 0 0 0 0 0 0 0 4226050 2700541 0 1669786 0 0 0 0 5533961 3036012 2482063 0 0 0 0 1385499 1423969 0 0 1930979 2106952 2580342 2194208 0 0 2440038 3602680 0 0 9380026 7963113 0 0 0 0 5094990 -AALEYGLK MGYG000001410_00799;MGYG000003170_00073 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella 1.0 COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,4PQYJ@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264311 0 0 0 0 427742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 329264 0 0 0 0 87699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830504 0 0 0 0 715467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1206225 0 0 0 0 1407383 0 0 0 -AALFGQTC(Carbamidomethyl)FNPGEAK MGYG000000262_02304;MGYG000000087_01966 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,25VA2@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 F 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 0 499747 0 0 0 328477 0 0 0 0 0 0 0 0 0 0 0 0 619414 0 0 0 0 0 616510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1311338 0 0 0 378240 0 0 0 1044388 0 0 0 0 0 0 0 0 1670369 1755160 780601 776619 0 0 1284384 0 0 0 0 0 0 0 0 1730783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALFGQTC(Carbamidomethyl)YNPGEAK MGYG000000198_04024 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways;PPAR signaling pathway;Plant-pathogen interaction 1.0 none 1.0 0 0 0 0 0 0 0 251917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154973 167940 396806 0 0 0 157124 0 0 0 0 0 0 0 0 0 0 0 0 0 283633 0 0 0 0 0 0 0 0 0 0 0 318440 0 0 0 0 0 3003512 1004842 1616848 0 0 0 1821481 1434110 0 0 658883 0 0 2276274 0 0 1182325 0 2886250 4409782 2619605 0 0 0 0 2086617 0 0 0 0 0 0 1250047 3401201 0 0 2388732 1040733 272129 418012 318066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270301 295843 0 0 0 0 0 0 0 0 0 0 0 0 338321 408090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALFLGR MGYG000000249_01571 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG1196@1|root,COG1554@1|root,COG1196@2|Bacteria,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,248K8@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Psort location 1.0 - 1.0 - 1.0 3.2.1.51 1.0 ko:K15923 1.0 ko00511,map00511 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH95 1.0 - 1.0 CHB_HEX_C_1,FIVAR,Glyco_hyd_65N_2,Laminin_G_3,NPCBM 1.0 - 1.0 GH95 1.0 GH95 1.0 GH95 1.0 alpha-L-fucosidase. Alpha-L-fucoside fucohydrolase. - an alpha-L-fucoside + H2O = an alcohol + L-fucose. 1.0 1.0 1.0 1.0 Other glycan degradation 1.0 none 1.0 420165 0 0 0 0 0 0 114373 0 0 0 0 0 0 0 0 0 0 0 282205 0 0 0 0 0 288875 0 0 0 0 0 0 0 0 214438 0 256044 0 1213023 0 0 0 0 0 0 1002081 0 0 0 0 0 0 0 0 0 0 0 1081647 0 0 0 0 0 1145383 0 0 0 0 0 0 0 0 1128727 0 1127833 0 369020 0 0 0 0 0 0 456224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93590 0 0 0 0 0 0 621956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353977 0 0 0 0 0 0 0 0 677798 0 106316 0 93968 0 0 0 0 0 0 334394 0 0 0 0 0 0 0 0 0 0 0 385602 0 0 0 0 0 280443 0 0 0 0 0 0 0 0 400079 0 78064 0 -AALFVVDVQK MGYG000000074_02444 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,22U1D@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 255647 0 0 294759 0 0 0 0 0 0 0 0 0 257756 0 0 0 0 255206 0 0 0 0 0 256475 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236416 0 0 0 0 0 0 0 0 0 284279 354602 0 201755 0 0 0 0 0 0 0 271633 0 0 0 0 0 0 0 0 0 0 0 0 0 640301 0 0 773826 0 0 0 0 0 0 0 555102 0 449918 748304 0 411730 0 410761 0 0 0 0 0 640403 0 0 0 0 0 0 0 0 0 0 0 0 0 387875 0 0 246978 0 0 0 0 0 0 0 160937 0 299502 268114 0 292202 0 308998 0 0 0 0 0 393987 0 0 0 0 0 0 0 0 0 0 0 0 0 1013892 0 0 1090534 0 0 0 0 0 0 0 566070 0 742584 1405327 0 660895 0 673540 0 0 0 0 0 1415078 0 0 0 0 0 0 0 0 -AALGAAIAVIGAGIGIGK MGYG000002478_03336;MGYG000000042_02496 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia,4ARQC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGAEGC(Carbamidomethyl)GK MGYG000000099_02237 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia,267QW@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 kdd 1.0 - 1.0 1.4.1.11 1.0 ko:K18012 1.0 ko00310,map00310 1.0 - 1.0 R03349 1.0 RC00888 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 1288058 0 645195 1822858 524263 585923 1078236 797014 843744 705112 560244 491299 638718 949443 913064 376292 585014 0 503657 465056 901543 264337 0 446934 1983339 921081 910974 0 1066899 777209 318250 395277 0 548750 990983 1139330 762161 454773 6072879 0 3094701 8000974 4036245 3630886 8403513 8806846 8058837 8535494 4463405 5447097 3193657 8307838 7650299 3575021 5719802 0 5783080 7186881 4840509 2947746 0 3163132 5169207 8137773 8188210 0 6258108 6688909 3338131 4547721 4986431 9930464 7853039 9127173 8473877 4758175 415135 0 109484 1145900 0 453678 324024 192708 966654 842187 279400 784016 0 824560 558948 275565 898382 0 898870 1424721 825284 426394 0 0 582773 396445 554153 0 772126 1017139 0 121071 449399 372853 680411 680777 611096 177640 986450 0 643703 563970 582793 413683 1260652 609901 719360 493050 645071 411619 449056 847240 970362 513844 659932 0 694667 775682 96789 680848 0 521952 966754 1121421 687132 0 604245 592910 923014 530344 511051 2360319 714109 708481 849748 725709 4622026 0 2956435 1380557 1317254 1726531 143197 2108014 2884357 2624098 490272 220365 1094174 1285787 3009187 2764661 1982919 0 1050102 3442671 4460114 2276397 0 2630795 2930773 2457780 4642862 0 655612 2359722 3444958 341737 626774 0 566519 2826498 3632512 3736226 -AALGAEGC(Cys->Xle)GK MGYG000000099_02237 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia,267QW@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 kdd 1.0 - 1.0 1.4.1.11 1.0 ko:K18012 1.0 ko00310,map00310 1.0 - 1.0 R03349 1.0 RC00888 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4095174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3036243 0 0 0 0 0 0 0 3109711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4224151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGAEGIGK MGYG000002926_00666;MGYG000002882_00083;MGYG000002794_00765;MGYG000002156_01166;MGYG000001733_00674;MGYG000002720_00859;MGYG000004196_01675;MGYG000002143_01957;MGYG000002953_01591;MGYG000004475_00754 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia 0.9 186801|Clostridia 1.0 C 0.9 alcohol dehydrogenase 0.9 kdd 0.9 - 1.0 1.4.1.11 0.9 ko:K18012 0.9 ko00310,map00310 0.9 - 0.9 R03349 0.9 RC00888 0.9 ko00000,ko00001,ko01000 0.9 - 1.0 - 1.0 - 1.0 ADH_zinc_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 0.9 0.9 0.9 0.9 Lysine degradation 0.9 none 1.0 7786031 4881187 2142091 6583164 0 6341504 10196745 5802658 6492259 5797016 3291419 2197349 0 7470173 9084159 0 3089399 4910174 4417787 6857523 3526475 5525089 1119715 6469708 7767893 6629312 5539174 1274753 7226843 670794 223757 1437193 2148472 8895158 5892504 7954896 9119600 1983244 4068937 1472861 157287 3261488 1319445 1322767 2745168 3701857 4297053 3368432 749601 2041539 0 2878114 2604882 1189616 739828 0 3798389 3614676 2338158 1188856 0 1662434 2046842 0 3785645 0 0 2351852 1332149 1867823 1133597 0 5050203 3880459 4686097 1834085 10990613 0 5697558 10403527 0 4690880 10138221 10180843 9170481 9613624 3479704 5555645 262374 10547213 10664676 3952813 10187502 0 11679016 9029191 8074356 7072124 0 4989218 8642475 8284346 10370479 0 7919161 9506623 3777048 6047824 7569573 9025027 9775128 9611238 9636033 0 4158472 9326963 5634913 5224381 5809353 6838185 7640814 5633356 5481539 7014856 4335812 4534315 3643483 5040721 4516130 4726575 6020958 0 5222976 5157679 3026932 5589441 1070658 6215581 4711685 4504617 4750390 1920198 8644235 4834608 4658206 8996009 5806005 4701287 5632823 4587138 4053297 6420853 1432755 1807772 418315 1150586 2493295 1038501 210232 1345845 560924 1836980 915906 3162658 828222 806423 835129 0 1938111 518631 1358020 0 0 1244845 603119 925902 345160 1302779 1115478 0 995715 0 378308 3211813 504277 1354897 2198440 1732283 639238 721143 -AALGAEGIGKDVTM(Oxidation)IIGN(Deamidated)GYTK MGYG000002926_00666;MGYG000002794_00765;MGYG000002156_01166;MGYG000001733_00674;MGYG000002720_00859;MGYG000004475_00754 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 kdd 1.0 - 1.0 1.4.1.11 1.0 ko:K18012 1.0 ko00310,map00310 1.0 - 1.0 R03349 1.0 RC00888 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 160962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGAEGIGKDVTMIIGN(Deamidated)GYTK MGYG000002926_00666;MGYG000002794_00765;MGYG000002156_01166;MGYG000001733_00674;MGYG000002720_00859;MGYG000004475_00754 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 kdd 1.0 - 1.0 1.4.1.11 1.0 ko:K18012 1.0 ko00310,map00310 1.0 - 1.0 R03349 1.0 RC00888 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 4654951 3371092 0 0 0 2286445 0 2772641 0 2415727 0 0 0 2970278 0 0 0 0 0 0 0 2596687 0 2100256 2235844 2530740 0 0 0 0 0 0 0 3263831 0 0 2617183 0 699661 506081 0 0 0 475119 0 1008094 0 1032309 0 0 0 597281 0 0 0 0 0 0 0 289587 0 325311 599399 1258195 0 0 0 0 0 0 0 696118 0 0 887259 0 0 1783387 0 0 0 1417233 0 0 0 3991263 0 0 0 0 0 0 0 0 0 0 0 0 0 914036 0 3124131 0 0 0 0 0 0 0 0 0 0 0 0 414205 603314 0 0 0 1423018 0 1930855 0 1339963 0 0 0 1738111 0 0 0 0 0 0 0 3111988 0 0 3998446 764598 0 0 0 0 0 0 0 4547513 0 0 0 0 114680 0 0 0 0 364407 0 227406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGAEGIGKDVTMIIGNGYTK MGYG000002926_00666;MGYG000002794_00765;MGYG000002156_01166;MGYG000001733_00674;MGYG000002720_00859;MGYG000004475_00754 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 kdd 1.0 - 1.0 1.4.1.11 1.0 ko:K18012 1.0 ko00310,map00310 1.0 - 1.0 R03349 1.0 RC00888 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 6556707 0 2266985 2578748 0 3183344 3685324 0 2977567 0 0 0 0 4833419 0 0 0 0 0 0 0 4228683 0 0 2799714 45171 0 0 0 0 0 0 0 6960526 0 0 13548155 5335117 1492740 0 0 2489680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1000655 0 826633 0 0 0 0 0 0 0 0 0 0 2549242 2109193 0 0 6898869 259107 0 6337894 0 0 5036483 0 0 0 0 5677933 0 0 0 0 0 0 0 0 0 0 4026580 14951269 0 0 0 0 0 0 0 0 0 0 0 7214218 1734297 0 2098785 3106415 0 0 3223076 0 0 0 0 0 0 946219 0 0 0 0 0 0 0 0 0 2651544 0 2853934 0 0 0 0 0 0 0 2658829 0 0 3770228 0 0 0 4383757 0 0 0 0 0 525220 0 0 0 0 6219359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGAFASYK MGYG000001356_00742 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter sp000177015|m__MGYG000001356 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1586368 0 0 0 0 0 0 0 0 0 -AALGAGVDKLANTVR MGYG000000245_00416;MGYG000002492_02075;MGYG000004271_02056;MGYG000000489_01318;MGYG000000271_00294 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 931140 980344 466432 986027 329161 651585 1076470 932549 984334 990027 1228604 0 709417 0 0 659631 907242 0 301733 521672 833127 578494 556366 568863 0 491189 896341 404311 811876 1623555 0 0 489707 0 0 742373 882592 415296 506692 366469 1010167 0 1404138 0 0 516215 0 0 978412 475300 634544 0 0 882653 262469 4953542 193287 0 419089 0 3542135 481119 0 369488 348433 3513764 384696 374452 0 0 1583539 0 0 522846 0 726470 2285405 2636548 4252975 2013459 2123811 2004079 2065679 2140584 2069617 1788040 2745556 3204047 2534893 0 0 3553420 2073326 1623205 1799095 1865459 1647148 1782024 2004717 1993696 0 2376346 2080165 2725671 2000417 2556529 0 0 4663076 0 0 1926755 2197663 4221696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588991 428325 483386 119910 309899 655929 568701 244912 512540 614387 145390 1573104 592851 0 0 386359 1022145 652592 780632 638055 441657 463703 703999 668918 0 286389 468194 994554 0 541007 0 0 458286 0 0 474885 454625 436919 -AALGAGVGADALDKAPQLTAESK MGYG000000187_00358 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG4677@1|root,COG5263@1|root,COG4677@2|Bacteria,COG5263@2|Bacteria,1UKUC@1239|Firmicutes,25G3Y@186801|Clostridia 1.0 186801|Clostridia 1.0 M 1.0 repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Beta_helix,CW_binding_1,Laminin_G_3 1.0 - 1.0 PL9_1 1.0 PL9 1.0 PL9_1 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 861856 0 0 0 0 712215 0 0 0 0 570310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGAHTPHDK MGYG000002619_00997;MGYG000002610_01679;MGYG000001300_01680;MGYG000002040_01831;MGYG000003166_01503 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4,Fer4_10,Fer4_4,Fer4_7,Fer4_8,Fer4_9,MTHFR_C,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 722850 0 88259 0 0 676940 0 0 0 451874 591527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 745134 0 887966 0 0 996670 0 0 0 721602 228658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302982 0 185780 0 0 604826 0 0 0 351663 883074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546042 0 254355 0 0 70225 0 0 0 326014 897841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 895968 0 172921 0 0 1047116 0 0 0 125373 466191 0 0 0 0 0 0 0 0 0 0 -AALGASESMR MGYG000002549_04076 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG0521@1|root,COG0521@2|Bacteria,4NKEX@976|Bacteroidetes,2FQAE@200643|Bacteroidia,4AK9S@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 COG NOG26372 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like,SusD-like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3974433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGDLTHVDAEK MGYG000002494_04209 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0614@1|root,COG0614@2|Bacteria,1NVK4@1224|Proteobacteria,1RRND@1236|Gammaproteobacteria,3ZMKD@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 P 1.0 periplasmic binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K02016 1.0 ko02010,map02010 1.0 M00240 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.14 1.0 - 1.0 - 1.0 Peripla_BP_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1093030 0 841854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGEAIAAVFSLAGAK MGYG000000074_01368 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FM0V@200643|Bacteroidia,22U4S@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase family M20/M25/M40 1.0 pepD_2 1.0 - 1.0 - 1.0 ko:K01270 1.0 ko00480,ko01100,map00480,map01100 1.0 - 1.0 R00899,R04951 1.0 RC00096,RC00141 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Glutathione metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1317355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8839409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGFK MGYG000000038_00759;MGYG000000171_02843;MGYG000000201_03874;MGYG000001617_01407;MGYG000001338_03374;MGYG000000142_00172;MGYG000000251_00063;MGYG000001315_01206;MGYG000002298_03446;MGYG000004733_01212;MGYG000002966_00551;MGYG000000200_01983 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.8333333333333334 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550889 774230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80494 0 0 0 0 0 -AALGIANVIVNSK MGYG000002485_02147 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0751@1|root,COG0751@2|Bacteria,378Q2@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 glycyl-tRNA synthetase beta 1.0 glyS 1.0 - 1.0 6.1.1.14 1.0 ko:K01879 1.0 ko00970,map00970 1.0 M00360 1.0 R03654 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DALR_1,tRNA_synt_2f 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine--tRNA ligase. glycyl-tRNA synthetase. - ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 731209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1091200 0 696013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGLAK MGYG000002528_00255 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,267VM@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 1.0 gpsA 1.0 - 1.0 1.1.1.94 1.0 ko:K00057 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00842,R00844 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 G3P_acyltransf,NAD_Gly3P_dh_C,NAD_Gly3P_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase [NAD(P)(+)]. L-glycerol-3-phosphate:NAD(P) oxidoreductase. The enzyme from Escherichia coli shows specificity for the B side of NADPH. (1) NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH. (2) NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGLDIDLK MGYG000002517_01313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate 1.0 punA 1.0 - 1.0 2.4.2.1 1.0 ko:K03783 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glu_synthase,PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Metabolic pathways;Nicotinate and nicotinamide metabolism;Purine metabolism;Biosynthesis of secondary metabolites;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102190 0 0 0 77033 0 0 0 0 0 0 0 0 0 0 72231 0 0 0 0 0 62126 0 0 0 0 0 0 0 0 0 80496 0 93787 0 582286 0 0 632465 0 0 0 590077 633373 0 0 0 0 621543 679191 0 499827 0 570425 721628 0 0 0 0 526727 649525 648655 0 0 0 0 0 0 0 690972 471555 714691 0 353933 0 0 0 0 0 0 0 209576 0 0 0 0 549790 546023 0 320487 0 394642 304848 0 0 0 0 341521 334890 423871 0 0 0 0 0 0 0 215649 300329 0 0 -AALGPYKGGLR MGYG000003686_00696;MGYG000004482_01468 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,2N73E@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 434138 0 0 0 0 0 0 0 826635 0 0 0 0 1394607 0 0 0 0 1150362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGQIEK MGYG000000201_01679 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066145|m__MGYG000000201 1.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3WGST@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 L 1.0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage 1.0 recA 1.0 - 1.0 - 1.0 ko:K03553 1.0 ko03440,map03440 1.0 M00729 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03400 1.0 - 1.0 - 1.0 - 1.0 RecA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Homologous recombination 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1538028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGTIR MGYG000002293_00342;MGYG000003697_01640 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 O 1.0 peptidylprolyl isomerase 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 116948 0 0 0 0 145625 0 0 0 0 0 0 237106 0 0 0 98777 304629 148170 0 0 0 322612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179124 0 0 0 0 0 0 213191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115238 0 0 0 0 0 240073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1043612 0 0 0 0 1428133 0 0 0 0 0 0 2461293 0 0 0 1310701 1547604 1137930 0 0 0 2272869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105580 0 0 0 0 106960 0 0 0 0 0 0 0 0 0 0 121373 274272 818623 0 0 0 155795 0 0 0 0 0 0 0 0 0 0 -AALGTSSFMSAASFQETTK MGYG000004797_04274;MGYG000000243_01979;MGYG000002478_00805 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 544475 0 434268 0 0 0 0 0 0 0 432093 0 0 380197 0 0 0 0 0 0 0 550381 0 0 0 0 0 0 593623 0 981904 0 0 0 0 515870 0 0 319095 0 758165 308346 0 0 0 0 612814 496068 1335066 0 0 1081136 0 0 0 483164 0 663998 0 632354 0 0 584291 0 0 0 325606 0 547610 0 0 0 0 395821 0 0 0 0 423944 0 0 0 0 0 0 0 478639 0 0 352104 0 548354 0 0 0 0 351540 0 0 0 0 448340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208303 0 479206 238793 0 0 0 0 448395 260735 971554 0 0 498134 0 665461 0 396958 0 312327 476191 371078 0 0 396811 501211 0 0 283160 0 0 0 0 0 0 338474 -AALGVLR MGYG000002494_02221 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,3XNJZ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Glycyl-tRNA synthetase beta subunit 1.0 glyS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.14 1.0 ko:K01879 1.0 ko00970,map00970 1.0 M00360 1.0 R03654 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 1.0 DALR_1,tRNA_synt_2f 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycine--tRNA ligase. glycyl-tRNA synthetase. - ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 69841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALGVVK MGYG000002989_00405 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Marvinbryantia|s__Marvinbryantia sp900544685|m__MGYG000002989 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALHEFNPMMGHR MGYG000002528_02478 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 111191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 451963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 693142 0 213438 0 0 0 0 571016 0 0 613414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161892 0 0 0 0 0 0 0 173021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALHILK MGYG000002478_03659;MGYG000004797_03013 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0156@1|root,COG0156@2|Bacteria,4NJ3B@976|Bacteroidetes,2G2VS@200643|Bacteroidia,4AW5T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.3.1.47 1.0 ko:K00652 1.0 ko00780,ko01100,map00780,map01100 1.0 M00123,M00573,M00577 1.0 R03210,R10124 1.0 RC00004,RC00039,RC02725 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 AMP-binding,AMP-binding_C,Aminotran_1_2,PP-binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 8-amino-7-oxononanoate synthase. AONS. The enzyme catalyzes the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis.-!-Pimeloyl-CoA can be used with lower efficiency. 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]. 1.0 1.0 1.0 1.0 Biotin metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 896327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 664832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579170 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 911041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALIAMTK MGYG000004526_00099 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-103|s__CAG-103 sp000432375|m__MGYG000004526 1.0 COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia,36DZX@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 IQ 1.0 Enoyl-(Acyl carrier protein) reductase 1.0 baiA 1.0 - 1.0 1.1.1.100,1.1.1.159 1.0 ko:K00059,ko:K00076 1.0 ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212 1.0 M00083,M00572 1.0 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-oxoacyl-[acyl-carrier-protein] reductase. | 7alpha-hydroxysteroid dehydrogenase. - Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates. | Catalyzes the oxidation of the 7alpha-hydroxy group of bile acids and alcohols both in their free and conjugated forms.-!-The Bacteroides fragilis and Clostridium enzymes can also utilize NADP(+). a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH. | cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH. 1.0 1.0 1.0 1.0 Biotin metabolism;Fatty acid metabolism;Fatty acid biosynthesis;Biosynthesis of unsaturated fatty acids;Metabolic pathways;Secondary bile acid biosynthesis;Prodigiosin biosynthesis 1.0 none 1.0 0 564665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1488132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALIDC(Carbamidomethyl)LA(Ala->Gly)PDR MGYG000002515_01045;MGYG000002535_02741;MGYG000002323_01572;MGYG000002494_01366;MGYG000002507_01860;MGYG000002506_00283;MGYG000000107_04278;MGYG000000235_02283;MGYG000003372_01027 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3WWJT@544|Citrobacter 0.3333333333333333 1236|Gammaproteobacteria 1.0 M 1.0 Belongs to the ompA family 0.3333333333333333 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 554478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302879 0 0 0 0 0 310717 0 0 0 0 0 0 0 786730 0 245046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1863413 0 0 1295693 0 0 0 1475521 0 0 0 0 0 0 0 0 0 0 0 1533938 0 0 0 0 0 1515975 1475460 0 0 0 0 0 0 2267749 0 2261325 1022810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALIDC(Carbamidomethyl)LAPDR MGYG000002515_01045;MGYG000002535_02741;MGYG000002323_01572;MGYG000002494_01366;MGYG000002507_01860;MGYG000002506_00283;MGYG000000107_04278;MGYG000000235_02283;MGYG000003372_01027 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3WWJT@544|Citrobacter 0.3333333333333333 1236|Gammaproteobacteria 1.0 M 1.0 Belongs to the ompA family 0.3333333333333333 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 7859875 7351315 6279329 7248504 5340209 12894151 11562350 10363299 8277908 9725269 5376269 5934874 3164478 7662817 7759540 3168510 7483414 0 6741078 6920239 7223701 18778750 0 20624615 7237834 7856888 6117414 0 9008215 9254485 8760773 7644207 6244982 9526557 9939434 8287408 7098149 7045450 31709586 64908026 59883260 26634400 61316308 110195129 47321126 25239554 34379381 56782876 16196868 30503091 29182920 43128413 34224862 40714831 83989050 0 59952637 31939761 74371458 136249751 0 104124303 60535010 30154013 25092361 0 103044598 60932675 26312583 36559927 75408513 27820440 27941299 29522403 28903228 50644599 6652939 5619099 7859564 5385742 7609065 14507481 7526695 8119668 6169331 6804873 5325105 7036995 6175451 6480874 5872433 7801187 6598554 0 5740805 6674658 6262454 12691820 0 11819686 6563572 6230678 6458557 0 6496347 7142047 9623892 5463754 6696642 7668770 6687147 7859091 5359225 7463571 14457568 11430822 13293802 11628834 9268428 16695151 16791981 15479497 10696752 15168972 6791297 8173088 12061010 10717293 12684748 10037167 10894792 0 9622404 11212757 14955136 17676401 0 15033424 12778995 11632930 12319475 0 12820557 11664328 8520576 9124340 14398951 21051369 18476173 16345870 9217737 11022991 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119527 0 0 0 0 0 0 0 0 0 0 0 102558 0 -AALIDC(Carbamidomethyl)LAPDRR MGYG000002515_01045;MGYG000002535_02741;MGYG000002323_01572;MGYG000002494_01366;MGYG000002506_00283;MGYG000002507_01860;MGYG000000107_04278;MGYG000000235_02283;MGYG000003372_01027 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3WWJT@544|Citrobacter 0.3333333333333333 1236|Gammaproteobacteria 1.0 M 1.0 Belongs to the ompA family 0.3333333333333333 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1626790 1435181 1547851 1537585 1270162 3148465 2072372 2167282 1976511 2321243 1007094 1596752 963792 1900342 1622318 958665 1685296 0 1645396 1609172 1738887 3479321 0 4475037 1843466 1874616 1540228 0 2289065 1835101 2031936 1836098 1434835 1889330 2148796 1799974 1626111 1559831 7161022 14182719 12569340 5253027 12454199 18432767 10665365 5991222 7415784 10827862 3762179 6488491 5752885 9096479 7414129 8874206 16225264 0 12341981 6153347 14916124 25880006 0 23485532 9589467 6919194 5847710 0 18327278 10993476 5646155 7378307 14908257 6229356 6652294 6356085 6311440 10572322 1484782 1361093 1733567 1597297 2053694 3425992 1942385 1830430 1394522 1735264 1407327 1811176 1602066 1527714 1393839 1568144 1479103 0 1471645 1551509 1732049 2457974 0 3298427 1608663 1478489 1435951 0 1528992 1556504 2148945 1519618 1540045 1869683 1656194 1523706 1154571 1691432 3061910 2053644 2859085 2552895 1947182 3546220 3476755 4484973 2080539 3822873 1514142 1909039 3237113 2282938 2565982 2439508 2134551 0 2330089 2504965 3794106 4761359 0 3351626 2861774 2449764 2642314 0 2364647 2164545 1583406 1939849 3281070 4752522 4006725 3403686 2093229 2597282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59127 0 0 0 0 0 0 0 -AALIDC(Carbamidomethyl)LAPDRRVEIEVK MGYG000002515_01045;MGYG000002507_01860;MGYG000002506_00283;MGYG000003372_01027 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3XMXT@561|Escherichia 0.5 1236|Gammaproteobacteria 1.0 M 1.0 Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes 0.5 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 751104 0 0 453489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459669 0 235348 0 0 0 0 0 0 582825 0 502868 0 0 0 0 636949 0 0 0 0 0 76603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179945 0 57925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86455 0 0 279012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216046 0 234277 0 0 0 0 0 0 261012 0 287541 94744 0 0 0 77206 0 0 289249 0 0 459766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407857 0 197030 0 0 0 0 0 0 72886 0 51973 485864 0 0 0 265236 0 0 412618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228561 0 193905 0 0 0 0 561324 -AALIDC(Carbamidomethyl)LGPDR MGYG000000093_01869 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Klebsiella_A|s__Klebsiella_A grimontii|m__MGYG000000093 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 M 1.0 Belongs to the ompA family 1.0 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2371395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALIDR MGYG000004899_03259;MGYG000001346_01624;MGYG000002549_04587 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALIEPYAC(Carbamidomethyl)SFHC(Carbamidomethyl)IER MGYG000004735_02293 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,248Z5@186801|Clostridia,27W1F@189330|Dorea 1.0 186801|Clostridia 1.0 E 1.0 Zinc-binding dehydrogenase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 544445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 669422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20292015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALIEPYAC(Trioxidation)SFHC(Carbamidomethyl)IER MGYG000004735_02293 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,248Z5@186801|Clostridia,27W1F@189330|Dorea 1.0 186801|Clostridia 1.0 E 1.0 Zinc-binding dehydrogenase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1326051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALIFGNIK MGYG000004735_00330 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 780599 2295010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254658 0 0 0 0 353891 0 0 0 775389 706287 0 0 0 0 586338 -AALIFGNVKPGDAATLM(Oxidation)DYTM(Oxidation)K MGYG000001338_02427;MGYG000000184_00682 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2276021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 576984 0 0 0 0 0 0 0 -AALIFGNVKPGDAATLM(Oxidation)DYTMK MGYG000001338_02427;MGYG000000184_00682 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 154909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 706962 0 0 0 0 0 0 0 0 341626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 565000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326993 0 0 0 0 0 0 0 -AALIFGNVKPGDAATLMDYTM(Oxidation)K MGYG000001338_02427;MGYG000000184_00682 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 790064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALIFGNVKPGDAATLMDYTMK MGYG000001338_02427;MGYG000000184_00682 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 0 0 0 1512075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8245839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALIFGNVTPGDAGTLM(Oxidation)K MGYG000000142_02504;MGYG000000050_00436;MGYG000004733_01559;MGYG000000212_01935;MGYG000000002_02256;MGYG000000201_00496;MGYG000000216_02766 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3XZDK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 acetyl-CoA decarbonylase synthase complex subunit beta 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 627041 809568 745084 0 0 1317009 0 947220 0 0 1141965 688296 0 656204 469510 0 1449182 0 0 1188966 641792 1110952 0 680571 858040 573785 0 0 995415 465985 1173971 0 0 0 0 0 525866 429753 242089 543267 0 0 0 410396 460548 0 0 0 0 399951 0 0 0 0 0 0 0 0 0 415077 0 682574 345126 0 0 0 667156 488009 1412169 0 346035 297907 0 0 0 344053 691507 1101931 614412 0 0 859137 576926 814437 0 0 425082 815769 0 570744 815667 629939 854280 0 796686 852199 834942 1699692 0 603642 633923 764858 0 0 874929 837282 848416 0 1014718 984615 0 0 649938 646117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALIFGNVTPGDAGTLMK MGYG000000142_02504;MGYG000000050_00436;MGYG000004733_01559;MGYG000000212_01935;MGYG000000002_02256;MGYG000000201_00496;MGYG000000216_02766 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3XZDK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 acetyl-CoA decarbonylase synthase complex subunit beta 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 954922 771412 1014719 422077 823758 1801615 514462 1513720 747277 1479741 1476644 1148306 1094821 591608 1049805 733865 1071712 716349 688184 987466 1377997 2006009 968361 745984 1025779 596063 919533 1278661 2474243 1397095 759304 665383 706458 661056 1032412 673626 620673 742331 1147689 768396 689598 855942 1143607 806917 1297287 1380124 773057 1025250 1262296 381075 1098603 576740 862164 460423 892052 2347925 806882 1387057 1366973 472932 863297 1497156 889706 849283 1451141 1690699 2400052 2324949 2904329 517796 1046159 1302531 1191144 1134576 1021924 997297 2531516 1263300 1453576 1188437 0 1743201 1813137 2749013 1187112 2106081 1066834 1568951 1429364 1717668 2674238 1765002 3481600 0 2578700 2632953 1744606 4377412 867813 1218983 2135149 2383450 2343093 976092 1553797 2620196 1785741 1535550 2773420 2679761 2389967 1163094 1842703 1803990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALIHGLK MGYG000000142_02038;MGYG000000301_00188;MGYG000000171_01879;MGYG000002025_01287;MGYG000001338_02782;MGYG000004740_00893;MGYG000002286_01563;MGYG000000532_01246;MGYG000001637_00006;MGYG000003694_02453;MGYG000002052_00761;MGYG000003422_00383;MGYG000000356_00499;MGYG000001456.1_01726;MGYG000000216_02331;MGYG000002670_00411;MGYG000003695_00625;MGYG000000076_02834;MGYG000000154_01812;MGYG000000245_02664;MGYG000000136_02053;MGYG000001186_01087;MGYG000000119_00072;MGYG000000201_02106;MGYG000002492_00401;MGYG000000050_01197;MGYG000000153_02068 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.8148148148148148 rpsK 0.8148148148148148 - 1.0 - 1.0 ko:K02948 0.8148148148148148 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 0.8148148148148148 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 2980201 5025421 2819383 1893463 4972556 4768399 1324647 2519099 1506931 1987895 4717975 2607400 4885458 2321624 2247587 4491183 3108265 5685198 1757152 4145426 3398618 4314778 2982071 1535945 2502304 1826400 1746952 3317866 2288705 2273956 1890918 4536151 3111868 3093570 2404606 1594568 2266306 3684185 2275951 7031892 3191555 1434278 2754679 1354643 1402579 1392205 1864189 965010 2205958 864268 2069496 1065558 873220 1126524 944898 3879405 1054025 1285009 0 832549 2246547 1590206 986468 1290281 1597170 3938373 2237067 1320085 6620438 2491271 3471755 2863145 2079944 2415033 1807790 3885272 3117534 7172919 9922660 3474882 3867650 3518785 2297905 3362076 2935963 3039936 4639184 2065805 5000900 2939464 3080794 6389887 4742326 3328899 2961982 2976629 3004954 4305325 3882197 2936192 3291893 2474952 3280647 4516710 3092840 3881988 4538019 7181339 9117490 3872738 3752886 2563537 3619265 8224292 1175743 4947741 1881914 1046670 0 1124555 1142968 937627 1056058 1549162 2424844 1720572 1950162 1057847 836298 2277073 1638851 1737002 922609 1586388 999398 1640083 1145046 1690681 1125480 728926 1122878 2164037 3166723 1366614 4425590 2934478 1997075 590401 822739 765354 837599 2230248 6033005 11117458 8524652 10182246 2063047 5503428 8643240 5778590 4617401 8016373 6858654 8289259 3027950 7477563 6448251 5586796 6151130 1400699 5856885 2229818 8037429 7410100 3494167 4830783 5072328 7448957 5854579 2988430 8502891 2688431 9277473 10447009 11154789 7100864 7535283 8659516 3826705 8175620 -AALIKENPLYGK MGYG000000080_03188 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD,NAD_binding_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1399535 0 0 0 0 0 0 0 0 0 -AALILSK MGYG000002528_00923;MGYG000000262_01647;MGYG000000028_00102 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,26AIX@186813|unclassified Clostridiales 0.6666666666666666 186801|Clostridia 1.0 H 1.0 Pantoate-beta-alanine ligase 0.6666666666666666 panC 1.0 - 1.0 6.3.2.1 1.0 ko:K01918 1.0 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 1.0 M00119 1.0 R02473 1.0 RC00096,RC00141 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pantoate_ligase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pantoate--beta-alanine ligase (AMP-forming). pantothenate synthetase. - (R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Metabolic pathways;beta-Alanine metabolism;Pantothenate and CoA biosynthesis;Biosynthesis of secondary metabolites 1.0 none 1.0 0 70263 0 0 0 361683 0 0 0 0 0 0 409003 0 0 0 0 0 0 0 0 403271 0 369598 0 0 0 0 0 0 0 573247 0 0 0 0 0 0 0 336130 0 0 0 330196 0 0 0 0 0 0 227540 0 0 0 0 0 0 0 0 247506 0 559445 0 0 0 0 0 0 0 227602 0 0 0 0 0 0 0 1733828 0 0 0 826318 0 0 0 0 0 0 725511 0 0 0 0 0 0 0 0 1548676 0 711481 0 0 0 0 0 0 0 1413167 0 0 0 0 0 0 0 431929 0 0 0 399231 0 0 0 0 0 0 303518 0 0 0 0 0 0 0 0 298767 0 310728 0 0 0 0 0 0 0 384104 0 0 0 0 0 0 0 292572 0 0 0 298269 0 0 0 0 0 0 200931 0 0 0 0 0 0 0 0 471968 0 368650 0 0 0 0 0 0 0 349909 0 0 0 0 0 0 -AALINVQR MGYG000001346_00032;MGYG000000236_00368 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,2FNN5@200643|Bacteroidia,4AP04@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG0058 Glucan phosphorylase 1.0 glgP 1.0 - 1.0 2.4.1.1,2.4.1.11,2.4.1.8 1.0 ko:K00688,ko:K00691,ko:K16153 1.0 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 1.0 - 1.0 R00292,R01555,R02111 1.0 RC00005,RC00049 1.0 ko00000,ko00001,ko01000,ko01003 1.0 - 1.0 GH65,GT3,GT35 1.0 - 1.0 DUF3417,Glycogen_syn,Phosphorylase 1.0 2.4.1.1 1.0 GT35 1.0 GT35 1.0 GT35 1.0 glycogen phosphorylase. | glycogen(starch) synthase. | maltose phosphorylase. polyphosphorylase. | UDP-glucose--glycogen glucosyltransferase. This entry covers several enzymes from different sources that act in vivo on different forms of (1->4)-alpha-D-glucans.-!-Some of these enzymes catalyze the first step in the degradation of large branched glycan polymers - the phosphorolytic cleavage of alpha-1,4-glucosidic bonds from the non-reducing ends of linear poly(1->4)-alpha-D-glucosyl chains within the polymers.-!-The enzyme stops when it reaches the fourth residue away from an alpha-1,6 branching point, leaving a highly branched core known as a limit dextrin.-!-The description (accepted name) of the enzyme should be modified for each specific instance by substituting 'glycogen' with the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, etc. | The description (official name) varies according to the source of the enzyme and the nature of its synthetic product.-!-Glycogen synthase from animal tissues is a complex of a catalytic subunit and the protein glycogenin.-!-The enzyme requires glucosylated glycogenin as a primer; this is the reaction product of EC 2.4.1.186.-!-A similar enzyme utilizes ADP-glucose (cf. EC 2.4.1.21). [(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. | [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D- glucosyl](n+1) + H(+) + UDP. | D-maltose + phosphate = beta-D-glucose 1-phosphate + D-glucose. 1.0 1.0 1.0 1.0 Necroptosis;Biofilm formation - Escherichia coli;Metabolic pathways;Starch and sucrose metabolism;Insulin resistance;Glucagon signaling pathway;Biosynthesis of secondary metabolites;Insulin signaling pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 474772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALIQC(Carbamidomethyl)LDRETYNK MGYG000001365_00393 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A|s__Phascolarctobacterium_A succinatutens|m__MGYG000001365 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4H1ZR@909932|Negativicutes 1.0 909932|Negativicutes 1.0 E 1.0 ABC transporter substrate-binding protein family 5 1.0 dppA 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143474 0 0 0 0 0 0 0 0 0 0 0 0 0 214867 0 0 0 0 0 0 0 316628 0 196990 0 230446 0 0 0 0 0 0 0 0 0 179382 261210 364708 0 0 0 0 0 0 0 0 0 0 0 0 0 247217 0 322817 0 0 0 0 198513 251568 0 294445 0 181840 0 0 698965 0 792905 330042 411305 0 0 456629 480708 413906 0 187539 0 0 0 0 0 0 195326 0 0 0 485895 329506 0 266691 0 0 0 515715 201337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341222 0 0 0 0 0 0 0 785245 0 1486648 1308128 1477518 0 0 938678 0 864630 1178709 762202 0 0 790722 1407684 1197254 0 790662 0 0 0 0 0 0 763263 0 0 0 895011 1909608 0 1168557 0 0 0 1045501 1574822 -AALITR MGYG000003500_01067;MGYG000001602_02150;MGYG000001464_00915;MGYG000002279_02623;MGYG000000095_03300;MGYG000002837_02841;MGYG000000255_00052;MGYG000004296_01212;MGYG000001310_00591;MGYG000000153_01249;MGYG000000164_02280;MGYG000000245_00949;MGYG000000271_00813;MGYG000004733_01566;MGYG000001300_02570;MGYG000000002_02264;MGYG000000532_02227;MGYG000000154_00209;MGYG000002517_01913;MGYG000004271_01584;MGYG000003702_00402;MGYG000001319_00319;MGYG000003381_00566;MGYG000000212_01942;MGYG000001315_00663 domain d__Bacteria 1.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia 0.32 186801|Clostridia 0.96 I 0.72 Glycerol-3-phosphate dehydrogenase 0.64 gpsA 1.0 - 1.0 1.1.1.94 1.0 ko:K00057 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00842,R00844 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 G3P_acyltransf,NAD_Gly3P_dh_C,NAD_Gly3P_dh_N 0.96 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase [NAD(P)(+)]. L-glycerol-3-phosphate:NAD(P) oxidoreductase. The enzyme from Escherichia coli shows specificity for the B side of NADPH. (1) NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH. (2) NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 897878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALITYDGK MGYG000002006_00574 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter sp900754605|m__MGYG000002006 1.0 2DX6Y@1|root,343NU@2|Bacteria,1VVG9@1239|Firmicutes,25GRP@186801|Clostridia,2N903@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1184375 0 0 0 0 864951 0 0 0 0 576394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372363 0 0 0 0 502954 0 0 0 0 578450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704037 0 0 0 0 561229 0 0 0 0 439927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635505 0 0 0 0 1449754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1066329 0 0 0 0 1005079 0 0 0 0 705481 0 0 0 0 0 0 0 0 0 0 -AALKDQDR MGYG000001338_02425;MGYG000000301_00509;MGYG000000133_01786 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism;Carbon metabolism 1.0 none 1.0 0 131036 0 0 0 0 0 32775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16579 0 0 0 0 0 32399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736936 0 0 0 0 0 243359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALKDQDRTFGYPSIVNLVK MGYG000001338_02425 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALKEVEALK MGYG000003899_02252;MGYG000002223_01363;MGYG000001300_01216 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3WHDD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 597385 0 724121 549001 0 0 307773 0 0 0 0 334985 0 477874 544977 0 419202 0 758765 589594 0 640134 0 0 0 449068 484443 0 0 0 0 0 644330 637638 0 419949 469666 589656 897534 0 635239 771731 0 559309 1182007 0 0 0 0 576613 0 830212 1027494 0 1056822 0 921852 869648 0 494159 0 524113 0 915530 824163 0 0 0 0 0 688340 1204130 0 964250 838867 981742 464215 0 71072 293783 0 367576 0 0 0 0 0 67357 0 53240 566427 0 58699 0 46067 458384 0 51120 0 0 0 313208 704897 0 0 0 0 0 60217 275620 0 0 122817 156855 838689 0 868875 851101 0 907347 1070478 0 0 0 0 957616 0 925617 674907 0 842079 0 803449 860081 0 679589 0 732306 0 740353 623016 0 0 0 0 0 951548 894419 0 801854 803390 935122 0 0 125790 41764 0 46297 80992 0 0 0 0 57382 0 0 74789 0 58171 0 0 0 0 212604 0 93262 0 0 56573 0 0 0 0 0 70085 0 0 0 50759 72088 -AALKEVSGIADEK MGYG000002528_02801 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia,36G65@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 PFAM Mannitol dehydrogenase 1.0 mtlD 1.0 - 1.0 1.1.1.17 1.0 ko:K00009 1.0 ko00051,map00051 1.0 - 1.0 R02703 1.0 RC00085 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Mannitol_dh,Mannitol_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 mannitol-1-phosphate 5-dehydrogenase. - - D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 720557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1920922 0 813041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 967735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALKN(Deamidated)QDRTFGYPSIVNLVK MGYG000000031_02024 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066205|m__MGYG000000031 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALKNK MGYG000004221_01655;MGYG000000989_01009 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia 0.5 186801|Clostridia 1.0 K 0.5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 0.5 rpoC 0.5 - 1.0 2.7.7.6 0.5 ko:K03046 0.5 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 0.5 M00183 0.5 R00435,R00441,R00442,R00443 0.5 RC02795 0.5 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 0.5 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 0.5 - 1.0 - 1.0 - 1.0 GH1 0.5 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 0.5 0.5 0.5 0.5 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704498 0 886936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALKPGEALLLENLR MGYG000003697_01048 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458101 0 0 0 0 565738 0 0 0 0 690230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALKPGEALMLENLR MGYG000004464_01207 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Barnesiellaceae|g__Barnesiella|s__Barnesiella sp900542255|m__MGYG000004464 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALKPGEVLLLENLR MGYG000003693_01612;MGYG000001306_01732;MGYG000002556_00160;MGYG000001783_01046;MGYG000002905_01347;MGYG000002560_01937;MGYG000004797_00163;MGYG000002478_02340 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 F 0.625 Psort location Cytoplasmic, score 0.5 pgk 0.625 - 1.0 2.7.2.3 0.625 ko:K00927 0.625 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.625 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.625 R01512 0.625 RC00002,RC00043 0.625 ko00000,ko00001,ko00002,ko01000,ko04147 0.625 - 1.0 - 1.0 - 1.0 PGK 0.625 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 0.625 0.625 0.625 0.625 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.625 none 1.0 49036 0 0 0 0 66355 0 0 0 0 0 0 0 0 0 49994 0 0 0 0 0 0 0 0 0 0 132317 0 0 0 0 103347 0 0 0 0 0 0 0 0 0 0 56532 83987 0 173255 70073 0 125823 99810 61959 0 0 0 0 212103 118648 105896 0 0 333958 0 0 224124 75769 241650 70627 0 161314 0 56837 44351 108694 0 50193 0 1353536 589112 1574411 0 1937839 866975 1299753 862076 1374768 0 740953 1338161 1965828 0 983492 1069337 576946 1502888 1204912 1304591 869779 479463 1254609 366557 1287029 809247 1147065 1104747 1027104 1180131 915884 608255 812232 831999 1012032 0 1144097 1260059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83689 0 0 0 0 0 0 0 0 0 -AALKSALTSK MGYG000002298_00329;MGYG000001338_02806 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALKTELGK MGYG000000271_02100 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 647711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALKVSAETGK MGYG000000084_02524;MGYG000004732_02304 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALLADEIAK MGYG000000077_02459;MGYG000004879_02866;MGYG000000262_01988 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25VEG@186806|Eubacteriaceae 0.6666666666666666 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1238274 1515919 1040615 817907 1391604 1315274 294464 1348208 417851 1299840 1084300 473291 1457891 797452 1385701 1520309 1105731 0 1088298 1405868 550540 1660217 0 367884 1461204 782193 1064426 0 243438 921893 648818 1436779 686677 964937 958751 442970 437105 800077 2422901 1744764 773087 2193799 830815 650770 3376521 1852157 2001105 1110924 559374 930070 612575 1038802 1085911 607912 752635 0 1666910 2591369 1404020 598136 0 2324165 1574657 1737693 599831 0 2938902 1029410 2038569 718255 684918 1044292 1847187 2520687 2141048 689091 5330588 5887285 1153716 8714446 913655 2981789 1782280 4763476 1827827 4266032 1421188 3489867 3140199 3597635 5553932 4125657 4500591 0 5426235 5305641 3514341 7043353 0 2010514 4791442 4498507 5634696 0 1221254 2933815 1049933 5302933 2425419 5728493 5799949 1748062 3545510 1384525 1439502 2345346 1089644 2131074 1702033 1856448 2506654 1127792 1259147 1851526 1809989 1145053 2004393 1843429 1049847 2961048 1985520 0 1120146 2145218 1155951 1801143 0 1441140 953600 666055 1397451 0 1810386 988248 1529771 1298814 1512039 174721 1278826 1180973 696177 1316108 297768 1809286 2024926 1164938 416524 1493054 1261423 1024243 509781 494335 2246881 476935 1663505 820963 624799 684807 704994 0 465154 502247 490615 2199684 0 2889988 425803 421891 460191 0 372121 434916 2512416 2068353 2593386 960163 424246 479135 358450 1400397 -AALLDR MGYG000001345_00516;MGYG000004899_03259;MGYG000002455_01538;MGYG000004876_00944;MGYG000001346_01624;MGYG000004876_03444;MGYG000002549_04587 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 0.8571428571428571 976|Bacteroidetes 1.0 J 0.8571428571428571 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 0.8571428571428571 pnp 0.8571428571428571 - 1.0 2.7.7.8 0.8571428571428571 ko:K00962 0.8571428571428571 ko00230,ko00240,ko03018,map00230,map00240,map03018 0.8571428571428571 M00394 0.8571428571428571 R00437,R00438,R00439,R00440 0.8571428571428571 RC02795 0.8571428571428571 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 0.8571428571428571 - 1.0 - 0.8571428571428571 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 GH13 0.8571428571428571 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 Purine metabolism;RNA degradation;Pyrimidine metabolism 0.8571428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALLEQGYDVK MGYG000001658_01343;MGYG000002098_01956 genus d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01 1.0 COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,3VNPE@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 P 1.0 ABC transporter, phosphonate, periplasmic substrate-binding protein 1.0 phnD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Phosphonate-bd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 1255558 0 0 0 0 0 0 0 0 0 996512 1492958 1116205 0 0 1226058 1082814 962250 851113 0 0 0 924451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330842 0 0 0 0 0 0 0 0 0 251893 412907 0 0 0 370546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448231 0 0 0 0 0 0 0 0 0 530400 820483 433218 0 0 0 347009 453462 454441 0 0 0 453138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269010 0 0 0 0 0 0 0 0 0 447106 257294 0 0 0 0 577745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 981412 0 0 0 0 0 0 0 0 0 802810 1028689 0 0 0 977653 1212173 1206879 1046354 0 0 0 1087307 0 0 0 0 0 0 0 0 0 0 -AALLER MGYG000001651_00540;MGYG000003455_00764;MGYG000003266_01536;MGYG000002794_01121;MGYG000002720_01011;MGYG000003899_00855;MGYG000002926_00046;MGYG000003819_00999;MGYG000002485_00113;MGYG000004828_00425;MGYG000004893_00824;MGYG000002968_01804;MGYG000002970_01755;MGYG000002156_00127;MGYG000003074_00264;MGYG000002105_01716;MGYG000004681_00606;MGYG000001567_01289;MGYG000002978_01886;MGYG000003074_00858;MGYG000004232_00775;MGYG000001642_01723 life d__Bacteria 0.9545 COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4CUBQ@84998|Coriobacteriia 0.3181818181818182 186801|Clostridia 0.5 C 0.5 Belongs to the Glu Leu Phe Val dehydrogenases family 0.5 - 0.45454545454545453 - 0.7727272727272727 1.4.1.4 0.3181818181818182 ko:K00262 0.3181818181818182 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 0.3181818181818182 - 0.5 R00248 0.3181818181818182 RC00006,RC02799 0.5909090909090909 ko00000,ko00001,ko01000 0.36363636363636365 - 1.0 - 1.0 - 0.9545454545454546 ELFV_dehydrog,ELFV_dehydrog_N 0.5909090909090909 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.3181818181818182 0.3181818181818182 0.3181818181818182 0.3181818181818182 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.3181818181818182 none 1.0 1047264 0 0 1033668 0 1491874 1207224 928447 0 963361 1259029 0 1237292 1268914 1065468 1282978 701832 2141036 2359290 0 0 1768163 2085813 1247955 0 945836 1055509 1917598 1394810 0 1266367 0 928313 0 0 0 1344751 1300993 0 0 0 0 0 0 0 0 0 0 704913 0 0 0 6939379 558738 826666 0 916593 0 0 630589 1420535 0 0 7220877 0 1748512 0 0 0 0 0 0 0 0 0 0 0 0 2791475 3976551 0 3646819 2021543 3575279 0 3140674 2617492 0 0 3553048 3880752 2971664 3951458 0 3832519 0 0 5056145 0 3348657 0 0 3931725 583073 0 0 2798873 0 3644629 0 0 0 3070673 3210675 1159298 0 1420139 463588 0 1400897 1038177 1123218 0 1581529 1341357 0 1201694 0 1249487 0 1863379 529384 1057562 0 0 1312582 537893 316525 0 688238 1300699 1730790 2132790 0 1729880 0 385562 0 0 0 955024 1609083 717191 0 0 511335 0 772072 348306 705749 0 664185 0 0 982923 574828 266298 809871 572849 439138 982390 0 0 0 0 429252 0 641004 299378 865451 1070073 0 0 0 0 0 0 0 0 421869 -AALLIQELAGGK MGYG000002438_03366 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,2FNBF@200643|Bacteroidia,22WG1@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily 1.0 pheT 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 1.0 6.1.1.20 1.0 ko:K01890 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 B3_4,B5,FDX-ACB,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 928771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 594472 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALLLDTK MGYG000002385_01836;MGYG000004893_01712;MGYG000004828_01848;MGYG000002506_01063;MGYG000003372_00726;MGYG000002494_00983;MGYG000002366_02567;MGYG000002485_02553 domain d__Bacteria 1.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,3XMTB@561|Escherichia 0.5 1236|Gammaproteobacteria 0.625 G 0.5 Pyruvate kinase 0.875 pykF 0.625 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 0.625 2.7.1.40 1.0 ko:K00873 1.0 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050 1.0 R00200,R00430,R01138,R01858,R02320 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iECO103_1326.ECO103_1819,iPC815.YPO2393 0.625 PK,PK_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate kinase. phosphoenol transphosphorylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Microbial metabolism in diverse environments;Type II diabetes mellitus;Carbon metabolism;Central carbon metabolism in cancer;Metabolic pathways;Viral carcinogenesis;Glycolysis / Gluconeogenesis;Glucagon signaling pathway;Human papillomavirus infection;Purine metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 171996 106106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112195 0 0 0 0 0 0 0 0 0 0 0 0 1900945 1071752 0 1118608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189195 0 0 0 2067989 0 0 0 0 0 0 0 0 0 0 0 0 523674 684375 0 590980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431972 0 0 0 0 0 0 0 0 0 0 0 0 0 259525 0 106191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471754 0 0 0 0 0 0 0 0 0 0 0 0 270582 0 0 117671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128206 0 0 0 253650 0 0 0 -AALLLDTKGPEIR MGYG000002385_01836;MGYG000004893_01712;MGYG000000953_00362;MGYG000004828_01848;MGYG000002506_01063;MGYG000003372_00726;MGYG000002494_00983;MGYG000002366_02567;MGYG000002485_02553 domain d__Bacteria 1.0 COG0469@1|root,COG0469@2|Bacteria,378U8@32066|Fusobacteria 0.4444444444444444 1236|Gammaproteobacteria 0.5555555555555556 G 0.5555555555555556 Pyruvate kinase 0.8888888888888888 pykF 0.5555555555555556 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 0.5555555555555556 2.7.1.40 1.0 ko:K00873 1.0 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050 1.0 R00200,R00430,R01138,R01858,R02320 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iECO103_1326.ECO103_1819,iPC815.YPO2393 0.5555555555555556 PK,PK_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate kinase. phosphoenol transphosphorylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Microbial metabolism in diverse environments;Type II diabetes mellitus;Carbon metabolism;Central carbon metabolism in cancer;Metabolic pathways;Viral carcinogenesis;Glycolysis / Gluconeogenesis;Glucagon signaling pathway;Human papillomavirus infection;Purine metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1175382 1533568 1575055 0 1882067 2340221 1526117 965430 0 1904795 547008 1203440 1045562 0 0 1103808 2026252 0 1349786 0 1799111 3163842 0 1738345 1618305 0 1080626 0 2203845 1839796 1080178 1076273 1709301 0 1141508 1328253 1056794 1379301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253783 104442 0 0 0 0 207835 0 0 0 0 0 0 0 0 213332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307432 278631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALLNATTVIDKAASK MGYG000003702_01296 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eisenbergiella|s__Eisenbergiella sp900066775|m__MGYG000003702 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALLPK MGYG000002494_02542 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,1RPCQ@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 C 1.0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases 1.0 qor 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003960,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016651,GO:0016655,GO:0017091,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:1901363 1.0 1.6.5.5 1.0 ko:K00344 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N,ADH_zinc_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NADPH:quinone reductase. zeta-crystallin. Specific for NADPH.-!-Catalyzes the one-electron reduction of certain quinones, with the orthoquinones 1,2-naphthoquinone and 9,10-phenanthrenequinone being the best substrates.-!-Dicoumarol (cf. EC 1.6.5.2) and nitrofurantoin are competitive inhibitors with respect to the quinone substrate.-!-The semiquinone free-radical product may be non-enzymically reduced to the hydroquinone or oxidized back to quinone in the presence of O2.-!-Abundant in the lens of the eye of some mammalian species. 2 a quinone + H(+) + NADPH = 2 a 1,4-benzosemiquinone + NADP(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALLTAEE(Cation_Al[III])CKSPIILGVSEGAGK MGYG000001689_03984 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia|s__Blautia coccoides|m__MGYG000001689 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZ5J@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALLTR MGYG000004828_01320;MGYG000002485_00846;MGYG000001300_02570 domain d__Bacteria 1.0 COG0240@1|root,COG0240@2|Bacteria,378MQ@32066|Fusobacteria 0.6666666666666666 32066|Fusobacteria 0.6666666666666666 I 1.0 Glycerol-3-phosphate dehydrogenase 1.0 gpsA 1.0 - 1.0 1.1.1.94 1.0 ko:K00057 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00842,R00844 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 NAD_Gly3P_dh_C,NAD_Gly3P_dh_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 glycerol-3-phosphate dehydrogenase [NAD(P)(+)]. L-glycerol-3-phosphate:NAD(P) oxidoreductase. The enzyme from Escherichia coli shows specificity for the B side of NADPH. (1) NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH. (2) NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Biosynthesis of secondary metabolites;Glycerophospholipid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 909551 0 0 0 0 676697 0 0 0 0 0 0 0 0 808920 0 0 0 1045338 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1236815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALLVR MGYG000002293_01440 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 EF 1.0 Carbamoyl-phosphate synthase (glutamine-hydrolyzing) 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 117079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 593038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALLYDEIDRNPLFR MGYG000000437_00029;MGYG000000003_02157;MGYG000001420_00882;MGYG000000074_00485;MGYG000001562_01481;MGYG000002203_01251 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,2FMET@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 798194 1216675 434106 996715 549219 864136 790262 424313 793653 1148543 168296 1264242 716277 671161 942996 510231 923657 0 1017838 1117754 997424 870140 0 1038211 829431 848732 1439338 0 679633 1667820 769791 0 735703 0 756244 1189189 1168154 404372 0 1093709 0 1764645 0 0 938239 1476729 0 0 1211271 1675481 916216 0 1755889 1187071 0 0 0 1850031 0 0 0 0 1356571 1648040 1477289 0 1698620 1833659 1038817 0 0 1082612 1182549 0 1599193 0 1056683 1202807 3775967 0 1050145 401920 1030096 845152 4952574 1188637 528666 1138861 786998 1726888 849673 626077 695019 0 1021624 1006861 1682759 634650 0 1746517 2045833 3596056 1685662 0 1922367 1100586 1377804 0 2253133 2021415 1324056 3842830 2756913 3174605 3418485 0 964281 2643832 4458792 0 3430768 4394275 1891751 4102048 3138892 3209476 4856260 3033446 4648111 3264648 2459874 0 2842721 4662857 5731273 5569759 0 0 4941740 5111374 2020518 0 5042846 4630041 5862089 0 6705511 0 2107451 2045793 6056483 6337158 9052523 14195465 9447061 10246587 30405206 6867737 9276434 7699132 8935485 9784444 11556881 6881800 0 24030301 14639521 6258255 9946453 0 25062619 30397023 11605148 23494940 0 19935957 19328297 4066829 10134992 0 2045976 15269931 0 0 0 4915 46280662 21073020 31873970 12314096 -AALLYNFLDNSK MGYG000000036_00319 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Pseudoruminococcus|s__Pseudoruminococcus massiliensis|m__MGYG000000036 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3WGD1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 387690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 930605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1456021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196912 0 0 0 0 -AALMDPAYMQK MGYG000002438_03725 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1390@1|root,COG1390@2|Bacteria,4NP16@976|Bacteroidetes,2FMD8@200643|Bacteroidia,22Y2E@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 subunit E 1.0 - 1.0 - 1.0 - 1.0 ko:K02121 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 vATP-synt_E 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1707399 0 0 0 0 0 268209 0 0 3416580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802140 0 0 0 0 0 0 0 0 3973152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2583161 0 0 0 0 0 752773 0 0 4005362 0 611059 0 0 0 0 624352 0 0 0 0 0 0 0 0 0 0 -AALN(Deamidated)ANDFAK MGYG000002603_01889;MGYG000001770_00650;MGYG000001056_01056;MGYG000002293_00413 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,2FMF1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 677809 0 0 0 0 867140 0 0 0 0 988640 0 0 0 0 0 0 0 0 0 432593 0 0 833540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1944164 0 0 0 0 1655933 0 0 0 0 1856712 0 0 0 0 1389172 0 0 0 0 1186705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALN(Deamidated)VSAETGHVITPHIMIPLVGEVK MGYG000001300_02837;MGYG000003921_00033 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1400258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNAAK MGYG000001871_00692 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__|s__|m__MGYG000001871 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,22W14@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNAGVK MGYG000002065_00792 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp002232035|m__MGYG000002065 1.0 COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4CV6B@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 Q 1.0 Amidohydrolase family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2549085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNAN(Deamidated)DFAK MGYG000002603_01889;MGYG000001770_00650;MGYG000001056_01056;MGYG000002293_00413 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,2FMF1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 280533 0 0 0 0 0 0 0 0 0 266819 0 0 0 0 452298 0 0 0 382955 643375 220511 0 0 0 296063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797550 0 0 0 0 0 493070 0 0 0 364543 0 0 0 0 0 0 0 0 0 0 0 0 454440 0 0 359784 0 0 0 0 0 0 409760 0 0 0 0 0 0 0 0 199927 0 557195 0 0 0 424005 0 0 0 0 269851 0 0 0 0 268276 0 0 1876336 0 0 2312751 0 0 0 0 0 0 1402708 0 0 0 0 3434131 0 0 0 0 4920429 460596 0 0 0 2959031 0 0 0 0 2436371 1459540 0 0 0 2240422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNANDFAK MGYG000002603_01889;MGYG000001770_00650;MGYG000001056_01056;MGYG000002293_00413 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,2FMF1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 289933 0 278912 515517 402983 376820 501688 470891 0 326222 712914 390303 308655 252326 0 387358 218709 248815 0 0 0 373215 426918 522630 201290 441484 0 166849 0 0 416896 517395 443117 413382 329928 0 547604 360362 0 0 0 677611 0 0 458567 596742 0 0 204371 565897 0 125307 0 284827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326577 0 452994 533190 666052 655214 568231 520159 0 0 605447 535035 579834 560485 0 278953 514902 778634 0 0 0 449659 348605 528791 745322 0 0 630557 0 0 538735 382708 0 449908 441727 0 647982 308743 0 0 26941534 8591188 15088863 25010938 9407547 12224190 0 8926293 25008433 10648029 16453635 8939563 0 12837544 8609195 58717931 0 0 0 29221717 60130450 31105626 11162134 9928046 0 40948399 0 0 11743631 9998129 28387816 12270371 10955731 0 10342197 26499244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNANDFAKAE MGYG000002293_00413 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,2FMF1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 425786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2046800 0 0 0 0 0 0 0 0 0 0 0 5343041 0 0 0 1916729 5670802 2291778 0 0 0 7054895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1428049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNATDAMEALK MGYG000002517_00130 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,24QPD@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding 1.0 csrA 1.0 - 1.0 - 1.0 ko:K03563 1.0 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019 1.0 - 1.0 - 1.0 - 1.0 CsrA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Biofilm formation - Vibrio cholerae;Biofilm formation - Pseudomonas aeruginosa;Biofilm formation - Escherichia coli;Two-component system 1.0 none 1.0 670853 0 0 796838 0 0 0 870789 498357 673131 0 0 0 712899 637593 0 0 0 788772 0 0 0 0 0 0 818820 677776 0 0 587121 0 0 0 0 562123 867692 0 0 402827 0 0 377074 0 0 0 460553 499731 270382 0 0 0 249582 203658 0 0 0 357020 0 0 0 0 0 0 357113 415403 0 0 335901 0 0 0 0 317922 464674 408660 0 272658 0 0 0 0 0 0 151217 371701 388803 0 0 0 484172 398645 0 0 0 672428 0 0 0 0 0 0 338512 365520 0 0 301648 0 0 0 0 359444 115432 294523 0 1228901 0 0 1041126 0 0 0 1436337 1356234 681335 0 0 0 1214932 1275646 0 0 0 841807 0 0 0 0 0 0 1598654 1193086 0 0 816010 0 0 0 0 1410493 1305577 2006833 0 1860386 0 0 452608 0 0 0 1825455 2129987 2102362 0 0 0 1682745 2301250 0 0 0 0 0 0 0 0 0 0 1862978 1868157 0 0 2405468 0 0 0 0 2002370 1972845 2385308 0 -AALNDDMMFRPL MGYG000001338_00105;MGYG000000184_02260 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3XYP0@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Galactose mutarotase-like 1.0 - 1.0 - 1.0 3.2.1.20 1.0 ko:K01187 1.0 ko00052,ko00500,ko01100,map00052,map00500,map01100 1.0 - 1.0 R00028,R00801,R00802,R06087,R06088 1.0 RC00028,RC00049,RC00077 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH31 1.0 - 1.0 DUF5110,Gal_mutarotas_2,Glyco_hydro_31 1.0 3.2.1.20 1.0 GH31 1.0 GH31 1.0 GH31 1.0 alpha-glucosidase. maltase-glucoamylase. Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.-!-The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links. Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Starch and sucrose metabolism 1.0 none 1.0 0 218186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1132731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNKK MGYG000001310_02091;MGYG000001374_01835;MGYG000000249_01353 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3XYK6@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 F 0.6666666666666666 Psort location Cytoplasmic, score 0.6666666666666666 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 829459 0 0 0 0 0 0 0 0 0 0 0 0 0 579137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 540028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 872577 0 0 0 0 1130399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723405 0 0 0 0 0 0 0 0 0 0 0 0 0 888039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1047348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNLK MGYG000001346_03130;MGYG000000196_03455;MGYG000004748_02411 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,2FMD0@200643|Bacteroidia,4AN66@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrB 0.6666666666666666 - 1.0 1.6.5.8 1.0 ko:K00347 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQR2_RnfD_RnfE 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4306765 0 0 0 0 0 0 1001108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12750909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNLMGK MGYG000000205_00558;MGYG000001338_01153 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,21XG4@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 E 0.5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) 1.0 dapA 1.0 - 1.0 4.3.3.7 1.0 ko:K01714 1.0 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 1.0 M00016,M00525,M00526,M00527 1.0 R10147 1.0 RC03062,RC03063 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHDPS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-tetrahydrodipicolinate synthase. dihydrodipicolinate synthetase. The reaction can be divided into three consecutive steps: Schiff base formation with pyruvate, the addition of L-aspartate-semialdehyde, and finally transimination leading to cyclization with simultaneous dissociation of the product.-!-The product of the enzyme was initially thought to be (S)-2,3- dihydrodipicolinate, and the enzyme was classified accordingly as EC 4.2.1.52.-!-Later studies of the enzyme from the bacterium Escherichia coli have suggested that the actual product of the enzyme is (2S,4S)-4-hydroxy- 2,3,4,5-tetrahydrodipicolinate, and thus the enzyme has been reclassified as 4-hydroxy-tetrahydrodipicolinate synthase.-!-However, the identity of the product is still controversial, as more recently it has been suggested that it may be (S)-2,3- dihydrodipicolinate after all.-!-Formerly EC 4.2.1.52. L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5- tetrahydrodipicolinate + H(+) + H2O. 1.0 1.0 1.0 1.0 Monobactam biosynthesis;Metabolic pathways;Lysine biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2318032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2297650 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNLVDNATTPLPR MGYG000001378_02876 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG4085@1|root,COG4085@2|Bacteria,4PN55@976|Bacteroidetes,2G0QX@200643|Bacteroidia,4AQT0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Fimbrillin-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BACON,Mfa_like_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1087059 0 0 0 0 913169 1340246 0 1288975 0 2690514 999137 0 0 937185 0 0 0 0 0 885066 634234 0 1274537 0 1038047 1130192 0 0 0 0 0 0 0 0 1525023 1022476 0 0 0 0 0 0 0 94849 0 57128 0 406838 0 0 0 74122 0 0 0 0 0 0 109439 0 0 0 0 75879 0 0 0 0 0 0 0 0 0 69096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1060380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147421 610723 0 612570 0 0 0 0 0 0 0 0 0 0 0 0 262717 0 -AALNNEVTNVLKEK MGYG000001400_03182 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Erysipelatoclostridium|s__Erysipelatoclostridium ramosum|m__MGYG000001400 1.0 COG1196@1|root,COG3525@1|root,COG1196@2|Bacteria,COG3525@2|Bacteria,1TQPP@1239|Firmicutes,25BQV@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Glycosyl hydrolase family 20, catalytic domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 F5_F8_type_C,FIVAR,Glyco_hydro_20,Glyco_hydro_20b,MucBP 1.0 - 1.0 GH20 1.0 GH20 1.0 GH20 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 4518831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNSQQGEPWQTIR MGYG000002494_01052 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1482@1|root,COG1482@2|Bacteria,1MUD8@1224|Proteobacteria,1RQX8@1236|Gammaproteobacteria,3ZISM@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Phosphomannose isomerase type I 1.0 manA 1.0 GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 5.3.1.8 1.0 ko:K01809 1.0 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 1.0 M00114 1.0 R01819 1.0 RC00376 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_696,iECOK1_1307.ECOK1_1731,iECS88_1305.ECS88_1659,iSFV_1184.SFV_1629,iSF_1195.SF1636,iSFxv_1172.SFxv_1833,iS_1188.S1767,iUMN146_1321.UM146_09090,iUTI89_1310.UTI89_C1801 1.0 PMI_typeI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 mannose-6-phosphate isomerase. phosphomannose isomerase. - D-mannose 6-phosphate = D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 565750 0 0 1028711 0 0 0 0 0 0 0 0 0 0 0 0 988887 0 0 1412296 0 866186 797809 0 0 0 930268 0 0 0 706680 0 0 0 0 511556 0 0 696580 0 0 495274 0 0 0 0 0 0 0 0 0 0 0 0 312379 0 0 0 0 320574 589651 0 0 0 373442 0 0 0 0 0 0 0 0 486539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNVK MGYG000000142_02834;MGYG000000463_01481;MGYG000000140_01464;MGYG000000417_00539;MGYG000003547_00119;MGYG000001698_00702;MGYG000000249_01089;MGYG000001315_01921;MGYG000001871_00692;MGYG000002963_02777;MGYG000000242_00224;MGYG000004296_00104;MGYG000002945_01502;MGYG000000133_02955;MGYG000002596_00549;MGYG000000201_02673;MGYG000002279_01986;MGYG000000251_01169;MGYG000004558_03187;MGYG000000383_01314;MGYG000003697_00176;MGYG000000164_00358;MGYG000000404_01435;MGYG000002966_02744;MGYG000002293_00650;MGYG000000187_00493;MGYG000002492_01692;MGYG000000806_02014;MGYG000000089_02490;MGYG000000243_00081;MGYG000003219_00291;MGYG000000002_01928;MGYG000001310_01399 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.2727272727272727 186801|Clostridia 0.8787878787878788 G 0.9090909090909091 Belongs to the PEP-utilizing enzyme family 0.6363636363636364 ppdK 0.9090909090909091 - 1.0 2.7.9.1 0.9090909090909091 ko:K01006 0.9090909090909091 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.9090909090909091 M00169,M00171,M00172,M00173 0.9090909090909091 R00206 0.9090909090909091 RC00002,RC00015 0.9090909090909091 ko00000,ko00001,ko00002,ko01000 0.9090909090909091 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9090909090909091 - 1.0 - 1.0 - 1.0 GT1 0.9090909090909091 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 0.9090909090909091 none 1.0 0 0 0 0 4395827 0 0 0 0 0 0 4287787 0 0 0 0 0 0 0 414734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2216072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4320730 0 0 0 0 3947903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9094760 4047464 0 0 0 0 0 0 0 0 0 6631438 0 0 0 0 0 5061095 0 0 2063235 1282346 0 0 1039716 0 0 0 0 0 0 913793 0 0 1208036 0 0 0 0 0 0 0 0 0 0 0 1734458 838691 0 0 0 723570 0 1885019 0 0 0 0 0 5657071 0 0 0 0 0 3455804 0 0 0 0 10400419 0 0 5795997 0 0 0 0 0 0 0 0 0 0 0 0 0 4402518 0 0 0 0 0 0 0 -AALNVQAK MGYG000001356_00630;MGYG000002727_00240 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.5 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNVQK MGYG000002035_01821;MGYG000002099_01951;MGYG000001687_00537;MGYG000000271_00388;MGYG000004735_00207;MGYG000004487_00114;MGYG000000245_03386;MGYG000001688_03814;MGYG000000258_01879;MGYG000001619_00896;MGYG000002926_01683;MGYG000002143_00035;MGYG000002707_01357;MGYG000003979_01382;MGYG000003074_00103;MGYG000004271_01396;MGYG000000152_05136;MGYG000003504_01005;MGYG000000099_03199;MGYG000002517_01243;MGYG000002025_01833;MGYG000002845_01363;MGYG000004475_00310;MGYG000002720_01364;MGYG000000131_01163;MGYG000003013_00135;MGYG000002794_01254;MGYG000000268_00698;MGYG000001496_03326;MGYG000001733_00637;MGYG000000076_02377;MGYG000003628_00298;MGYG000001607_01964;MGYG000000387_01345;MGYG000001439_01567 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.37142857142857144 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8285714285714286 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 0.9714285714285714 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 2889189 2449255 8433559 4076321 2752624 0 0 0 0 0 0 4979941 6411642 8532124 3834748 3865164 0 6466400 6339059 0 0 0 0 9262495 0 0 4291037 0 7746102 0 0 2483149 0 0 0 0 0 0 0 252515 0 0 498279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2548864 0 0 0 0 0 0 0 0 0 0 0 2584337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4790627 0 8477072 6119867 0 0 0 9646218 0 0 0 0 0 0 0 0 0 8194178 0 0 0 0 0 0 0 7849092 0 0 18117579 0 0 0 0 0 0 0 0 10593652 0 13526726 0 0 4697162 0 0 20086994 0 0 0 0 0 0 0 0 0 26880874 0 0 0 0 11922321 15119520 5893735 17294558 0 0 14743022 15168050 0 14595042 14802306 0 36180806 29569563 15591715 0 4211982 15045923 18875001 12405861 0 9315907 17725309 0 29800835 0 6152148 0 10692897 10483270 3939086 17631752 25201924 0 46462220 0 22605665 -AALNVQKK MGYG000002720_01364;MGYG000000131_01163;MGYG000000271_00388;MGYG000002794_01254;MGYG000004487_00114;MGYG000000245_03386;MGYG000001733_00637 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.7142857142857143 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 0.8571428571428571 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 306572 0 1107483 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNVSAETGC(Carbamidomethyl)MITPH MGYG000000022_02788 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1192127 0 0 0 0 1079589 0 0 0 0 1135880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 772007 0 0 0 0 1110784 0 0 0 0 948882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1582674 0 0 0 0 2272961 0 0 0 0 2149208 0 0 0 0 0 0 0 0 0 0 -AALNVSAETGHVITPH MGYG000001300_02837;MGYG000003921_00033 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 2017927 2071405 2507129 2225214 648301 1852408 1408423 944430 1638011 0 1599224 1246798 2248453 1759252 2282723 2286621 2364378 2761071 2642005 2299060 925717 2158406 2370240 1537233 2510016 2141003 2558314 2275653 664407 1111788 1621789 1225965 2170107 2184159 944054 1928117 1518874 1988352 7422716 4169482 5607486 6221557 3409377 5036856 8616943 2702646 8390909 1458637 3437226 5562069 3454904 8032832 5964075 4114197 7274533 2618713 8448025 8745649 2891815 3437379 2436866 4803966 8585713 8727405 6747915 2308217 1340581 5031467 5693537 3252152 5116339 5988745 2418663 6922538 6723868 4906426 1088968 515331 745270 1491836 655025 544468 1121480 414127 1068447 381945 1209753 1127304 797349 1413927 1228760 932357 440632 876765 757718 1094632 720183 505365 1226283 927485 1042609 1107659 688623 1191564 553434 760783 698948 539660 685060 1209707 116076 1205254 1054998 623148 3764053 5900611 8322200 4909315 7184434 6647891 7218602 2157903 5495616 4718966 5371485 5542543 6102437 5542260 3974795 5975095 5968346 3572784 6194193 5334426 4314004 6982492 2880224 6492153 3683206 3056746 4728992 4700960 2724284 5358075 9373188 5910612 9252169 3457070 1420868 4034515 4467747 9266004 0 116758 0 197696 490032 128091 0 91922 175985 148831 206029 476411 237929 0 0 185496 113069 666785 0 121258 135137 263642 810468 255133 96761 0 0 868976 204003 284650 104053 582709 0 0 170872 0 0 0 -AALNVSAETGHVITPHIM(Oxidation)IPLVGEVK MGYG000001300_02837;MGYG000003921_00033 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 296979 0 492352 0 0 304362 111737 0 257977 0 243169 261865 0 255204 265372 0 407047 0 0 355487 164467 364498 0 190818 0 234337 0 0 0 0 242050 0 337049 273050 0 249916 169353 324784 382097 0 356473 0 0 397278 594082 0 754841 0 356190 408892 0 582261 505392 0 459149 0 0 494239 202751 277262 0 319018 0 427254 0 0 0 0 522364 0 380643 537449 0 453924 500681 484465 211386 0 0 0 0 0 0 0 0 0 119797 305083 0 0 203069 0 0 0 0 0 88362 0 0 0 0 0 0 0 0 0 90369 0 0 0 0 105694 176462 0 85108 0 499710 0 0 110640 107442 0 96794 0 136939 462023 0 259805 189952 0 86444 0 0 249520 2652108 40960 0 0 0 132161 0 0 0 0 97595 0 555966 1376300 0 51294 841804 307197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALNVSAETGHVITPHIMIPLVGEVK MGYG000001300_02837;MGYG000003921_00033 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 9376998 7937471 137078 0 6689289 0 0 0 4155191 4185865 0 8222564 0 0 0 0 0 0 0 0 8387322 0 5493127 0 0 0 0 0 0 0 0 8858740 0 0 5732497 0 14159067 0 16799933 5517436 7443380 0 12726868 0 0 0 0 11934100 0 6788026 0 0 0 0 0 0 0 0 0 0 17864148 0 0 0 0 0 0 0 0 7756918 0 0 10682207 0 5969942 0 0 0 0 0 0 0 0 0 1751709 0 0 0 0 0 0 0 0 0 0 0 0 0 3006004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2121634 9384680 0 0 1777473 0 0 0 4526371 3425643 0 11347508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3237008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALPADVNAPK MGYG000002395_01221;MGYG000003452_01305;MGYG000003683_00172;MGYG000001490_01230 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4D0QF@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit 1.0 rplT 1.0 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 1.0 - 1.0 ko:K02887 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 E3_binding,Ribosomal_L20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 621621 745431 1350682 0 0 579568 0 600394 0 0 673054 0 0 0 715591 1922715 484636 0 0 931271 0 453168 0 578667 0 498534 387393 0 522815 0 328651 383801 955984 0 0 365597 472630 1405829 1484166 1419867 3038459 0 0 3665010 0 1525030 0 0 1722784 0 7246278 0 0 2014446 873756 0 0 1637586 0 2219882 0 7082882 0 1194454 1680587 0 2212589 0 3238309 1003272 2534540 0 0 2031336 1490723 3867049 1689495 1863439 1363587 0 0 0 0 0 0 0 0 0 1387262 0 2131464 2963921 1731323 0 0 2230808 0 635522 0 0 0 1067159 2026525 0 1216655 0 0 1385445 3363016 0 0 0 0 877663 0 629910 0 0 0 0 0 0 0 0 1454517 0 0 0 0 2044039 616362 0 0 0 0 3009271 0 3117661 0 0 0 0 1118777 0 792884 0 0 0 0 0 0 620967 0 0 0 0 0 0 0 0 0 0 639005 0 680728 0 0 228475 0 0 0 0 0 0 0 0 0 462724 0 0 0 0 0 0 0 0 0 0 430174 0 -AALPADVNAPKEA MGYG000003683_00172 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4D0QF@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit 1.0 rplT 1.0 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 1.0 - 1.0 ko:K02887 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 E3_binding,Ribosomal_L20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALPAIFNPEDLNALEQALR MGYG000002960_00221;MGYG000002438_02893;MGYG000003697_02506;MGYG000000098_00813;MGYG000000196_04138;MGYG000001056_01453;MGYG000002293_02658;MGYG000001337_03724;MGYG000000243_00603;MGYG000004629_01151;MGYG000004885_01160 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia 0.45454545454545453 976|Bacteroidetes 1.0 C 1.0 Electron transfer flavoprotein 0.5454545454545454 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 18845745 0 422202 0 152279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 510040 0 0 0 0 0 22266078 1695231 15473522 5815058 0 21732754 568455 2424947 85357 0 0 0 0 20941279 91771 0 0 0 0 0 0 60074 0 0 0 0 14479172 0 0 0 247365 10341879 277338 0 0 0 0 0 0 78127 12668588 15543202 0 20806966 161047 18516562 16727005 0 0 0 0 17525922 7529249 0 0 0 0 0 0 2201821 0 0 0 0 16283701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4704549 9822892 4484428 0 0 0 0 4340679 0 0 0 0 0 0 21142559 0 0 0 0 25387761 0 0 0 3066837 22576398 12128644 0 0 0 16668242 0 0 16548172 9463686 15933014 0 6621923 13104261 735686 19369064 20002988 0 0 0 19643618 5669478 0 0 0 0 0 0 0 0 0 0 0 23889807 0 0 0 21688662 0 8685933 0 10765910 0 0 0 8742909 14164778 26079479 15462037 0 7307783 27398507 0 23065506 -AALPEAKPVLMEPIGELK MGYG000002794_00741;MGYG000002926_00766;MGYG000001824_01321;MGYG000002720_00009;MGYG000004525_01177 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes 1.0 1239|Firmicutes 1.0 J 1.0 elongation factor G 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 978893 0 767705 1193092 0 0 0 0 0 0 0 0 0 0 0 0 690327 0 549232 0 823735 0 0 0 0 896739 0 0 0 0 0 0 945032 0 0 0 0 0 0 0 0 200969 0 0 0 0 0 0 0 0 0 0 0 0 211214 0 0 0 0 0 0 0 0 164718 0 0 0 0 0 0 98443 0 0 0 0 0 595443 0 401804 691084 0 0 0 0 0 0 0 0 0 0 0 0 641432 0 563064 0 545754 0 0 0 0 640182 0 0 0 0 0 0 521607 0 0 0 0 0 187006 0 280705 339246 0 0 0 0 0 0 0 0 0 0 0 0 142952 0 330646 0 391808 0 0 0 0 228161 0 0 0 0 0 0 165230 0 0 0 0 0 0 0 109088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALPEQVQIWK MGYG000002494_03187 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0134@1|root,COG0135@1|root,COG0134@2|Bacteria,COG0135@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,3WWTA@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Indole-3-glycerol phosphate synthase 1.0 trpC 1.0 GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 4.1.1.48,5.3.1.24 1.0 ko:K13498 1.0 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 1.0 M00023 1.0 R03508,R03509 1.0 RC00944,RC00945 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330 1.0 IGPS,PRAI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 indole-3-glycerol-phosphate synthase. | phosphoribosylanthranilate isomerase. indoleglycerol phosphate synthetase. | PRAI. In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24). | In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.1.3.27 and EC 4.2.1.20). 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)- 1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O. | N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1- deoxy-D-ribulose 5-phosphate. 1.0 1.0 1.0 1.0 Biosynthesis of amino acids;Metabolic pathways;Biosynthesis of secondary metabolites;Phenylalanine, tyrosine and tryptophan biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 864311 0 0 1795031 0 0 0 0 0 854431 0 0 0 0 1132054 0 0 0 0 2623069 0 1556264 1240558 0 0 0 0 0 0 0 879587 0 0 0 0 678070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALPHGLK MGYG000001315_01363 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,25QPE@186804|Peptostreptococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfE 1.0 - 1.0 - 1.0 ko:K03613 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS05585 1.0 FMN_bind,Rnf-Nqr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALPIGEALPASPGAAAGK MGYG000002528_02478 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 276684 0 0 0 0 0 0 0 0 0 0 0 552295 0 0 0 239685 234197 0 0 0 0 421481 0 0 0 0 0 0 0 0 0 0 0 476410 0 0 0 292941 0 0 0 0 0 0 0 0 0 0 0 2062355 0 0 0 0 1147105 639581 0 0 0 1685860 0 0 0 311610 0 0 0 0 0 0 0 2474826 429441 0 0 1309242 0 0 0 726240 0 824120 0 569846 598604 0 759108 443620 1419028 0 0 3647241 1088998 816895 0 0 682160 1427539 2582637 0 0 2398072 876120 652643 0 0 0 568051 0 1244127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 770671 0 0 0 0 0 168045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217433 0 0 0 0 331166 0 0 0 0 0 0 0 0 0 0 -AALPLHHLVEK MGYG000002494_03189 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,3WWIJ@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 E 1.0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate 1.0 trpA 1.0 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 4.2.1.20 1.0 ko:K01695 1.0 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 1.0 M00023 1.0 R00674,R02340,R02722 1.0 RC00209,RC00210,RC00700,RC00701,RC02868 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECED1_1282.ECED1_1467,iECP_1309.ECP_1308 1.0 Trp_syntA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 tryptophan synthase. tryptophan synthetase. The alpha-subunit catalyzes the conversion of 1-C-(indol-3- yl)glycerol 3-phosphate to indole and D-glyceraldehyde 3-phosphate (this reaction was listed formerly as EC 4.1.2.8).-!-The indole migrates to the beta-subunit where, in the presence of pyridoxal 5'-phosphate, it is combined with L-serine to form L-tryptophan.-!-In some organisms this enzyme is part of a multifunctional protein that also includes one or more of the enzymes EC 2.4.2.18, EC 4.1.1.48, EC 4.1.3.27 and EC 5.3.1.24.-!-In thermophilic organisms, where the high temperature enhances diffusion and causes the loss of indole, a protein similar to the beta subunit can be found (EC 4.2.1.122).-!-That enzyme cannot combine with the alpha unit of EC 4.2.1.20 to form a complex. (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan. 1.0 1.0 1.0 1.0 Metabolic pathways;Phenylalanine, tyrosine and tryptophan biosynthesis;Glycine, serine and threonine metabolism;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1046273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1620562 0 1012820 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139593 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALPTINYLVEHNAR MGYG000002557_00596;MGYG000001709_02050;MGYG000001718_00620;MGYG000002050_01271;MGYG000000188_00828;MGYG000003073_01053;MGYG000004746_01527;MGYG000001636_00874;MGYG000003274_01602;MGYG000003851_00622;MGYG000004681_01192;MGYG000002919_00267;MGYG000000333_00451;MGYG000002775_01123;MGYG000002970_00370;MGYG000000802_01544 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CUGT@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 969119 2209372 893285 395441 555670 540865 234803 730275 494060 651576 939173 652033 1477151 0 486588 1431139 490329 581067 501583 529807 296238 845271 573209 306232 0 478826 546995 826444 826325 712782 827336 0 752874 0 360092 768258 471471 467580 467591 659576 266872 506860 584931 213625 670870 753433 423664 480976 913325 471293 918154 0 353415 563026 274088 1628397 350018 625067 261879 236647 741890 614505 0 505501 761217 1461777 641316 626704 0 0 183752 0 499424 508593 384042 299405 627914 704810 298743 522435 200181 324595 391280 613366 257785 525694 332559 492705 749976 0 617124 1027790 1103409 256627 580144 660735 564413 691161 536811 219717 0 495385 696199 561242 730015 690730 285084 0 567343 0 742650 330214 483895 365453 391132 167839 144165 293200 464954 231482 244857 244449 236611 273111 597927 222134 1181349 0 213363 975591 328299 93634 219500 237439 297084 357759 0 247572 0 131149 337761 0 299732 537143 120918 0 164938 0 160415 150117 243456 151725 219268 260458 197416 339071 204598 119638 450788 281508 176625 357974 523748 330961 440801 0 296043 573302 193111 172646 129668 158912 391759 175804 340685 209032 0 160798 458814 475230 154238 132834 405954 0 517911 0 62246 196374 143562 124187 -AALPTIQK MGYG000001300_02037;MGYG000000245_03070;MGYG000002274_01739;MGYG000002517_01027;MGYG000000022_00457;MGYG000000255_01167;MGYG000000909_00645;MGYG000000489_00504;MGYG000002040_00807;MGYG000000193_03246 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 0.6 186801|Clostridia 1.0 F 0.6 Belongs to the phosphoglycerate kinase family 0.6 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 654904 0 0 0 0 0 327639 0 0 0 0 0 0 0 0 0 932554 0 0 0 0 0 0 0 0 0 0 0 0 0 310878 620691 0 0 0 198404 0 0 234229 0 0 0 0 0 239021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204749 243204 0 0 0 207804 0 0 837376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 523337 0 0 0 0 0 0 0 0 0 0 0 0 0 759711 659495 0 0 0 630707 0 0 1378834 0 0 0 0 0 2477575 0 0 0 0 0 0 0 0 0 2264351 0 0 0 0 0 0 0 0 0 0 0 0 0 1606831 1975625 0 0 0 1434928 0 0 985489 0 0 0 0 0 870861 0 0 0 0 0 0 0 0 0 1131999 0 0 0 0 0 0 0 0 0 0 0 0 0 947465 1278571 0 0 0 865266 -AALPTLK MGYG000003694_01736;MGYG000000038_02186;MGYG000003922_03393;MGYG000000365_01000;MGYG000000138_00869;MGYG000000045_02628;MGYG000003701_03777;MGYG000004552_00730;MGYG000000415_01539;MGYG000000262_01196;MGYG000003628_01098;MGYG000000119_00719;MGYG000001490_00976;MGYG000003828_01579;MGYG000001687_00180;MGYG000002360_00441;MGYG000004727_00660;MGYG000001797_01330;MGYG000003684_03801;MGYG000001707_00062;MGYG000002528_00366;MGYG000001374_01835;MGYG000001461_01243;MGYG000000181_00012;MGYG000001739_01299;MGYG000003921_00578;MGYG000000404_00343;MGYG000002966_00074;MGYG000000231_00609;MGYG000004271_00555;MGYG000002120_01321;MGYG000000002_02119;MGYG000002186_02387;MGYG000003431_02005;MGYG000003702_00926;MGYG000000359_00927;MGYG000003363_01096;MGYG000000003_00285;MGYG000004828_01577;MGYG000000258_00429;MGYG000000170_00153;MGYG000002716_01347;MGYG000000154_00118;MGYG000001529_02777;MGYG000000378_01265;MGYG000004185_02169;MGYG000004740_01467;MGYG000003937_01847;MGYG000004006_01975;MGYG000003926_00185;MGYG000000037_01258;MGYG000004532_01918;MGYG000000806_01931;MGYG000004733_01784;MGYG000000263_01340;MGYG000000142_01978;MGYG000000087_02748;MGYG000000212_01475;MGYG000001617_03190;MGYG000000501_00895;MGYG000002974_01419;MGYG000002992_00163;MGYG000003279_01634;MGYG000002395_00974;MGYG000001338_02546;MGYG000000383_00714;MGYG000001602_01804;MGYG000003681_00986;MGYG000000164_00799;MGYG000002105_00517;MGYG000003452_00954;MGYG000002281_01909;MGYG000000375_01448;MGYG000002084_00948;MGYG000000217_00276;MGYG000000584_00984;MGYG000004468_00582;MGYG000004493_00203;MGYG000002707_01010;MGYG000002574_00010;MGYG000000200_02456;MGYG000003683_00472;MGYG000001310_02091;MGYG000003542_01331;MGYG000000044_00323;MGYG000000018_00079;MGYG000000050_00594;MGYG000000118_02693;MGYG000000080_03114;MGYG000000953_00944;MGYG000002549_02739;MGYG000003891_01912;MGYG000002279_00558;MGYG000002438_03839;MGYG000000139_00882;MGYG000002787_01666;MGYG000001327_01861;MGYG000004501_00310;MGYG000004876_02584;MGYG000003409_01919;MGYG000002445_01919;MGYG000001334_01648;MGYG000001489_04176;MGYG000000196_04506;MGYG000004250_00307;MGYG000000301_01011;MGYG000001661_02348;MGYG000001199_01004;MGYG000004791_00980;MGYG000000204_00777;MGYG000002072_00619;MGYG000001635_02145;MGYG000001319_00347;MGYG000000074_02205;MGYG000001157_01540;MGYG000002155_01252;MGYG000000414_01789;MGYG000004519_00424;MGYG000000187_02265;MGYG000000013_01224;MGYG000000171_00851;MGYG000001292_01114;MGYG000000467_01931;MGYG000002485_02479;MGYG000000175_00766;MGYG000002455_00199;MGYG000000398_00287;MGYG000000249_01353;MGYG000001683_01828;MGYG000004893_01505;MGYG000000271_03251;MGYG000000089_01321;MGYG000000562_01219;MGYG000000084_00216;MGYG000000133_02282;MGYG000003252_01520;MGYG000004735_01945;MGYG000002109_01277;MGYG000002298_02411;MGYG000002098_01090;MGYG000002289_02222;MGYG000002949_03160;MGYG000001141_01007;MGYG000004594_01443 domain d__Bacteria 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H2GV@909932|Negativicutes 0.13194444444444445 186801|Clostridia 0.5 F 0.5208333333333334 Belongs to the phosphoglycerate kinase family 0.5 pgk 0.9930555555555556 - 0.9305555555555556 2.7.2.3,5.3.1.1 0.6805555555555556 ko:K00927,ko:K01803 0.6805555555555556 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6805555555555556 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9930555555555556 R01015,R01512 0.6805555555555556 RC00002,RC00043,RC00423 0.6805555555555556 ko00000,ko00001,ko00002,ko01000,ko04147 0.9930555555555556 - 1.0 - 1.0 - 0.9652777777777778 PGK,TIM 0.6736111111111112 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 0.6805555555555556 0.6805555555555556 0.6805555555555556 0.6805555555555556 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.6805555555555556 none 1.0 1812213 1888248 1138396 1797989 1744448 1530037 2140715 1766184 1874087 1764647 4357615 2013435 1545331 2174164 1788549 2218454 1714517 814445 1552038 1838935 2258227 1869313 1330597 2353038 1751139 1891096 1936322 924820 1961745 1964442 1793886 2385802 1516688 2230232 2043372 1820517 2247650 1392699 3035754 1920770 2748568 2380253 2573448 2039756 1985698 3124713 2887617 3517251 3785975 3776768 1833376 3028755 2956128 2505860 2678097 3489152 2286425 2404666 4263643 2564323 934052 1699648 2587014 2685777 2520765 1762119 2291874 2987042 1522114 2248167 2268770 2399448 3144281 2751671 2854879 2975356 2610276 2146374 3308137 2566884 4367167 3191036 3724149 2660178 0 2483370 5091675 2596871 2375712 3102024 2403220 2948845 2980514 5442549 2312777 2514961 3725705 2504890 4539107 4008021 2568981 2349579 2492347 3459167 3152536 3430716 3793351 3128510 2836790 2330152 1462407 3455533 2579393 3174587 3055982 2765078 2983003 2638664 3018746 3001746 3383231 2877966 2896883 3483065 4246752 4039655 3766582 2538675 3097035 4049489 2687263 2620506 2785516 2738489 5053034 2183227 2597390 0 2617892 2801265 2844389 2889658 2738301 3885098 0 3126311 2812530 3531452 3254101 3750187 3251341 2450882 2766927 2844585 2164887 2740522 5349829 3974579 0 3984868 3299346 3082748 4631825 6172193 3561908 1770284 2751991 3636763 2926387 4372589 2444830 3575384 6383143 3762087 2933181 2974063 2564540 2102309 2408977 2994912 2613710 7123104 2261309 4389407 1453576 3198584 0 2132524 2597741 2190677 -AALPTLKK MGYG000004468_00582;MGYG000000038_02186;MGYG000003922_03393;MGYG000000262_01196;MGYG000000415_01539;MGYG000001310_02091;MGYG000000044_00323;MGYG000004727_00660;MGYG000002528_00366;MGYG000002549_02739;MGYG000002279_00558;MGYG000002438_03839;MGYG000000139_00882;MGYG000000404_00343;MGYG000003921_00578;MGYG000004271_00555;MGYG000000002_02119;MGYG000004876_02584;MGYG000003702_00926;MGYG000002445_01919;MGYG000003363_01096;MGYG000001489_04176;MGYG000000196_04506;MGYG000000301_01011;MGYG000000003_00285;MGYG000000258_00429;MGYG000001661_02348;MGYG000000170_00153;MGYG000004185_02169;MGYG000004740_01467;MGYG000003937_01847;MGYG000000074_02205;MGYG000000414_01789;MGYG000003926_00185;MGYG000004733_01784;MGYG000000142_01978;MGYG000000087_02748;MGYG000000212_01475;MGYG000000013_01224;MGYG000001617_03190;MGYG000000171_00851;MGYG000002455_00199;MGYG000003279_01634;MGYG000001683_01828;MGYG000001338_02546;MGYG000000271_03251;MGYG000001602_01804;MGYG000000164_00799;MGYG000002105_00517;MGYG000000084_00216;MGYG000000133_02282;MGYG000004735_01945;MGYG000002109_01277;MGYG000002098_01090;MGYG000000584_00984 domain d__Bacteria 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H2GV@909932|Negativicutes 0.18181818181818182 186801|Clostridia 0.41818181818181815 G 0.5272727272727272 Belongs to the phosphoglycerate kinase family 0.5636363636363636 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 0.6 ko:K00927,ko:K01803 0.6 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 0.6 RC00002,RC00043,RC00423 0.6 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 0.6 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 0.6 0.6 0.6 0.6 Inositol phosphate metabolism;Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 0.6 none 1.0 1020952 0 542599 0 813214 0 929407 0 0 0 1637533 748985 0 1129956 0 0 0 267411 0 0 885593 0 553273 0 0 563269 0 363202 0 817780 0 1294088 760232 1176012 0 0 854028 778869 1323029 0 1328949 0 904606 0 627902 0 0 0 1409094 409335 0 997710 0 0 0 0 0 0 1108044 0 321287 0 0 974639 0 0 0 1032030 0 1385384 1176556 1250288 0 0 1516989 1132962 799035 0 1481099 0 1873663 0 1369727 0 0 0 2054605 1006891 0 1102162 0 0 0 2147274 0 0 1324295 0 1623134 0 0 739437 0 1516658 0 1086241 0 946838 1113817 1004607 0 0 1254248 1329324 950545 0 946772 0 864877 0 701816 0 0 0 1307026 1510230 0 689795 0 0 0 550157 0 0 1963849 0 681630 0 0 1684660 0 600381 0 1170866 0 1128052 846463 1125141 0 0 1009647 146931 907827 0 868141 0 1612280 0 975031 0 0 0 2990143 1758329 0 534328 0 0 0 1849918 0 0 1868706 0 1870697 0 0 1443681 0 721673 0 2533198 0 2145754 613877 1553180 0 0 1201718 1122835 -AALQAEIDANNAAVK MGYG000002720_01061 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3WHDD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 339407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311657 0 76825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477689 0 331287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104566 0 83123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALQDEFGLNKDGSPVMAMVTR MGYG000003937_01118 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3WGRA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Synthesizes alpha-1,4-glucan chains using ADP-glucose 1.0 glgA 1.0 - 1.0 2.4.1.21 1.0 ko:K00703 1.0 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 1.0 M00565 1.0 R02421 1.0 RC00005 1.0 ko00000,ko00001,ko00002,ko01000,ko01003 1.0 - 1.0 GT5 1.0 - 1.0 Glyco_transf_5,Glycos_transf_1,HC2 1.0 2.4.1.21 1.0 GT5 1.0 GT5 1.0 GT5 1.0 starch synthase. starch (bacterial glycogen) synthase. The description (accepted name) varies according to the source of the enzyme and the nature of its synthetic product, e.g. starch synthase, bacterial glycogen synthase.-!-A similar enzyme utilizes UDP-alpha-D-glucose (cf. EC 2.4.1.11). [(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-alpha-D- glucosyl](n+1) + ADP + H(+). 1.0 1.0 1.0 1.0 Metabolic pathways;Biosynthesis of secondary metabolites;Biofilm formation - Escherichia coli;Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALQGASLNVYINTK MGYG000001338_02421;MGYG000000184_03366;MGYG000000200_00062 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Methenyltetrahydrofolate cyclohydrolase 1.0 fchA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FTCD_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 283728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 647277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 960626 322402 0 0 0 0 0 0 0 819199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 638742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 778052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 503148 529859 0 0 0 0 0 0 -AALQLK MGYG000000084_00626;MGYG000003937_01088;MGYG000001346_00290;MGYG000001531_02895 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WH8V@541000|Ruminococcaceae 0.5 186801|Clostridia 0.75 C 0.75 Psort location Cytoplasmic, score 0.75 - 0.75 - 0.5 1.3.1.108 0.75 ko:K03521,ko:K22431 0.5 - 0.75 - 1.0 - 0.75 - 0.75 ko00000,ko01000 0.75 - 1.0 - 1.0 - 1.0 ETF 0.75 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 0.75 0.75 0.75 0.75 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2784725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALQQVK MGYG000002455_03412 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1537545 0 0 0 0 1057616 0 0 0 0 958815 0 0 0 0 0 0 0 0 0 0 -AALQQVVEQYHPDR MGYG000000022_02863;MGYG000002545_01583;MGYG000002274_00511 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,3WGTH@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 CobW/HypB/UreG, nucleotide-binding domain 1.0 cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CobW_C,cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 614815 0 0 0 0 489003 0 0 0 0 463630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1023113 0 0 0 0 1143109 0 0 0 0 809431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1589409 0 0 0 0 1961693 0 0 0 0 1560005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 441745 0 0 0 0 490939 0 0 0 0 419853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1706144 0 0 0 0 2059329 0 0 0 0 2214645 0 0 0 0 0 0 0 0 0 0 -AALQTAEANVAAAK MGYG000002867_01551;MGYG000000074_00445;MGYG000001415_00462;MGYG000000053_00168 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,2FN62@200643|Bacteroidia,22UYI@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family 1.0 - 1.0 - 1.0 - 1.0 ko:K03585 1.0 ko01501,ko01503,map01501,map01503 1.0 M00646,M00647,M00699,M00718 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 1.0 2.A.6.2,8.A.1.6 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cationic antimicrobial peptide (CAMP) resistance;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498095 354492 359793 539073 348111 0 368696 331247 641736 464332 349504 0 312525 387223 457304 222233 0 0 0 451779 1098183 228671 0 0 198226 564878 276825 0 636311 1205819 228385 221427 274327 0 0 417324 585792 0 0 0 0 601036 0 729585 455037 0 0 0 0 0 0 524283 0 0 0 0 0 0 482076 0 0 488681 0 0 0 0 0 821259 0 0 446474 0 0 298280 0 320699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 833478 0 0 0 0 0 0 0 0 0 1744926 1201267 2020095 3224336 2239399 2281082 2297465 1658313 2922699 1943856 1291649 0 1623727 1642906 1877184 1889104 2746951 0 0 2925183 2341238 1657799 0 1688501 1779938 2085881 1525235 0 1618276 5103309 1666283 1363777 335403 0 0 2672699 2621845 2212462 -AALQTAEANVEAAK MGYG000000003_02125 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,2FN62@200643|Bacteroidia,22UYI@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family 1.0 - 1.0 - 1.0 - 1.0 ko:K03585 1.0 ko01501,ko01503,map01501,map01503 1.0 M00646,M00647,M00699,M00718 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 1.0 2.A.6.2,8.A.1.6 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cationic antimicrobial peptide (CAMP) resistance;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2517670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1418963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 509394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405285 0 0 0 0 0 0 0 0 -AALQTNSFMSAASFQETTK MGYG000002438_02330 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,22VWB@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519387 0 0 0 0 0 0 0 0 -AALQTSSFMSAASFQETTK MGYG000001789_00145;MGYG000000196_03983;MGYG000002549_02931;MGYG000000236_01798;MGYG000004763_01698;MGYG000001345_04693;MGYG000001346_01525;MGYG000001313_00088 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 813353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641710 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALQVVK MGYG000002528_02344;MGYG000000028_01311 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 phosphate acetyltransferase 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 898269 0 0 0 0 606365 0 0 0 0 789466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1633539 0 0 1984692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 998948 0 0 0 0 0 0 0 0 0 0 0 0 0 1050968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1082763 0 0 0 0 468717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALREDPDVILVGEMR MGYG000001319_00715;MGYG000000089_01669 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,4BWDG@830|Butyrivibrio 0.5 186801|Clostridia 1.0 NU 1.0 Type II/IV secretion system protein 0.5 pilT 1.0 - 1.0 - 1.0 ko:K02669 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02035,ko02044 1.0 3.A.15.2 1.0 - 1.0 - 1.0 T2SSE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1015144 0 0 0 0 1808535 0 0 0 0 1367579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALSDYYR MGYG000001300_01631;MGYG000001255_00890;MGYG000002641_02297;MGYG000003899_00049;MGYG000002274_00762;MGYG000000022_02058 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3WITG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Fe-S iron-sulfur cluster assembly protein, NifU family 1.0 nifU 1.0 - 1.0 - 1.0 ko:K04488 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 391497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 727603 0 0 0 0 555044 0 0 0 0 534882 0 0 0 0 0 0 0 0 0 0 0 535105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1380726 0 0 0 0 1495577 0 0 0 0 1159639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1341850 0 0 0 0 1077488 0 0 0 0 1010613 0 0 0 0 0 0 0 0 0 0 0 762680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858425 0 0 0 0 909896 0 0 0 0 696484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 937169 0 0 0 0 991801 0 0 0 0 699291 0 0 0 0 0 0 0 0 0 0 -AALSMTIPTGTGIHR MGYG000000196_02404;MGYG000004876_03241;MGYG000000236_00877;MGYG000000170_02306 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0673@1|root,COG0673@2|Bacteria,4NGP9@976|Bacteroidetes,2FMTZ@200643|Bacteroidia,4AKIQ@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 E 1.0 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate 1.0 ddh 0.75 - 1.0 1.4.1.16 1.0 ko:K03340 1.0 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 1.0 M00526 1.0 R02755 1.0 RC00006 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding,DAPDH_C,GFO_IDH_MocA,NAD_binding_3,Semialdhyde_dh 0.75 - 1.0 - 1.0 - 1.0 - 1.0 diaminopimelate dehydrogenase. meso-diaminopimelate D-dehydrogenase. - H2O + meso-2,6-diaminoheptanedioate + NADP(+) = (S)-2-amino-6- oxoheptanedioate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Lysine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 935157 0 0 1931573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1089755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 664869 0 0 1448544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 639370 0 0 0 0 0 0 0 0 -AALSMTIPTGTGIHRR MGYG000000196_02404;MGYG000004876_03241;MGYG000000236_00877;MGYG000000170_02306 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0673@1|root,COG0673@2|Bacteria,4NGP9@976|Bacteroidetes,2FMTZ@200643|Bacteroidia,4AKIQ@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 E 1.0 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate 1.0 ddh 0.75 - 1.0 1.4.1.16 1.0 ko:K03340 1.0 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 1.0 M00526 1.0 R02755 1.0 RC00006 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding,DAPDH_C,GFO_IDH_MocA,NAD_binding_3,Semialdhyde_dh 0.75 - 1.0 - 1.0 - 1.0 - 1.0 diaminopimelate dehydrogenase. meso-diaminopimelate D-dehydrogenase. - H2O + meso-2,6-diaminoheptanedioate + NADP(+) = (S)-2-amino-6- oxoheptanedioate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Lysine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 959336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALSNSFC(Carbamidomethyl)EVSLQPYGVFTHR MGYG000002494_01895 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,3XM7I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde 1.0 argC 1.0 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.2.1.38 1.0 ko:K00145 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028,M00845 1.0 R03443 1.0 RC00684 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iSSON_1240.SSON_4131 1.0 AA_kinase,Semialdhyde_dh,Semialdhyde_dhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 N-acetyl-gamma-glutamyl-phosphate reductase. NAGSA dehydrogenase. - N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 249616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253632 0 292898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1251469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1666923 0 993197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALSNTFGFGGHNAC(Carbamidomethyl)AIVK MGYG000002438_01705 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,2FNDB@200643|Bacteroidia,22W73@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP 1.0 fabF 1.0 - 1.0 2.3.1.179 1.0 ko:K09458 1.0 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 1.0 M00083,M00572 1.0 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 1.0 RC00039,RC02728,RC02729,RC02888 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 Ketoacyl-synt_C,ketoacyl-synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 beta-ketoacyl-[acyl-carrier-protein] synthase II. KAS II. Involved in the dissociated (or type II) fatty acid biosynthesis system that occurs in plants and bacteria.-!-While the substrate specificity of this enzyme is very similar to that of EC 2.3.1.41, it differs in that palmitoleoyl-ACP is not a good substrate of EC 2.3.1.41 but is an excellent substrate of this enzyme.-!-The fatty-acid composition of Escherichia coli changes as a function of growth temperature, with the proportion of unsaturated fatty acids increasing with lower growth temperature.-!-Controls the temperature-dependent regulation of fatty-acid composition, with mutants lacking this acivity being deficient in the elongation of palmitoleate to cis-vaccenate at low temperatures. (9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)- octadecenoyl-[ACP] + CO2 + holo-[ACP]. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis;Biotin metabolism;Metabolic pathways;Fatty acid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90739 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 827236 0 0 0 0 0 0 -AALSNTFGFGGHNAC(Carbamidomethyl)VIVK MGYG000000042_00641;MGYG000000243_01872;MGYG000001306_02492 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,2FNDB@200643|Bacteroidia,4ANNA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP 1.0 fabF 1.0 - 1.0 2.3.1.179 1.0 ko:K09458 1.0 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 1.0 M00083,M00572 1.0 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 1.0 RC00039,RC02728,RC02729,RC02888 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 Ketoacyl-synt_C,ketoacyl-synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 beta-ketoacyl-[acyl-carrier-protein] synthase II. KAS II. Involved in the dissociated (or type II) fatty acid biosynthesis system that occurs in plants and bacteria.-!-While the substrate specificity of this enzyme is very similar to that of EC 2.3.1.41, it differs in that palmitoleoyl-ACP is not a good substrate of EC 2.3.1.41 but is an excellent substrate of this enzyme.-!-The fatty-acid composition of Escherichia coli changes as a function of growth temperature, with the proportion of unsaturated fatty acids increasing with lower growth temperature.-!-Controls the temperature-dependent regulation of fatty-acid composition, with mutants lacking this acivity being deficient in the elongation of palmitoleate to cis-vaccenate at low temperatures. (9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)- octadecenoyl-[ACP] + CO2 + holo-[ACP]. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis;Biotin metabolism;Metabolic pathways;Fatty acid metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406558 0 0 0 0 612185 0 0 0 0 307246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2035800 0 0 0 0 1405032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256574 0 0 0 0 333434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 933262 0 0 0 0 669591 0 0 0 0 564026 0 0 0 0 0 0 0 0 0 0 -AALTADAIAK MGYG000004594_00959;MGYG000004735_00207;MGYG000001698_00702 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.3333333333333333 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.6666666666666666 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10660147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2698179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALTADDIAK MGYG000000142_02834;MGYG000000463_01481;MGYG000002298_01806;MGYG000000140_01464;MGYG000000171_00241;MGYG000004733_01907;MGYG000000268_00698;MGYG000003450_00463;MGYG000003819_01577;MGYG000000031_02405;MGYG000000249_01089;MGYG000001619_00896;MGYG000004517_00262;MGYG000002926_01683;MGYG000000252_02480;MGYG000001315_01921;MGYG000000089_02490;MGYG000000127_02901;MGYG000001310_01399;MGYG000004296_00104 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.55 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.75 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 6614630 6635460 7871410 3838188 8021079 11179069 2723887 8705793 4701067 5854881 10184453 6880191 8045078 5435754 8310964 7698876 5821439 13505742 5235494 7305265 6274004 8909107 12433936 5147840 7905061 5821353 5465947 10370721 5905542 4724936 4223711 5250986 6582859 6322648 6358126 4279474 6082012 8845629 0 9594387 8639244 6434491 7616748 4741382 8210311 8301897 6444160 6125274 6755039 3527922 8210378 0 4666758 4597815 16168082 12341899 5959648 8363509 5799110 0 6301328 8794603 7506471 6147958 7711884 8857986 9735523 5580797 13730163 8260531 0 9528051 9651174 0 7185507 12391392 0 6829234 7616711 9197161 4137743 7406100 7821518 9199418 7794358 0 5416026 6503133 6767122 10089619 11367985 8512583 0 6660334 9646899 0 7819739 13488577 11728881 7589681 10154483 8388645 10620581 8297703 0 9076638 7996990 8798166 9533083 11897641 0 6841810 10095103 8251450 3094468 3649301 6444872 3355890 3943780 3308034 3409865 3253944 2632578 3786485 3418256 6035140 5415059 3250832 3016547 4766367 9642959 2850910 2658334 3679156 2538732 3714382 1902008 3162173 2298991 2002765 3251063 8578137 7175466 2554610 4869106 2804437 7295997 546083 3370743 3151139 2093998 7987365 4892029 2917070 0 5236186 2690219 6010043 0 6410365 4012194 4893956 3449533 4008816 1759423 6172880 5054932 3409616 4216773 3967505 5900515 3412480 4554180 7319653 6527187 6263969 4542911 5814091 4860628 7448211 5998071 1864261 5247607 3537946 12228404 5435416 5584707 4393312 3139058 8433338 -AALTADEIAK MGYG000004221_00458;MGYG000002229_00282;MGYG000002006_01658;MGYG000004482_00393;MGYG000002079_00687;MGYG000004667_00970;MGYG000002727_00240;MGYG000001319_00729;MGYG000000115_00663;MGYG000002609_02142;MGYG000002143_00035;MGYG000002057_00345;MGYG000000728_00587;MGYG000002247_01703;MGYG000003116_01723;MGYG000003503_00176;MGYG000004726_03204;MGYG000001531_01607;MGYG000001136_01739;MGYG000003581_02331;MGYG000001374_00487;MGYG000001577_00663;MGYG000004663_01541;MGYG000002393_00923;MGYG000000352_00288;MGYG000004380_01725;MGYG000004475_00310;MGYG000000242_00224;MGYG000000212_00440;MGYG000002139_00077;MGYG000004764_00308;MGYG000001665_01593;MGYG000000076_02377;MGYG000004526_01655;MGYG000001699_00078;MGYG000001607_01964;MGYG000000159_02392;MGYG000001756_01779;MGYG000000387_01345;MGYG000000187_00493;MGYG000000184_00575;MGYG000004784_01123;MGYG000001439_01567;MGYG000000371_01679;MGYG000000806_02014;MGYG000004743_00400;MGYG000000489_00801;MGYG000000915_00888;MGYG000002035_01821;MGYG000002099_01951;MGYG000004487_00114;MGYG000002159_01291;MGYG000000278_00304;MGYG000000417_00539;MGYG000000280_02154;MGYG000004785_01840;MGYG000000154_00436;MGYG000000245_03386;MGYG000002831_00019;MGYG000002753_00264;MGYG000002707_01357;MGYG000000036_01410;MGYG000000045_00432;MGYG000000146_01902;MGYG000001707_02428;MGYG000003504_01005;MGYG000001497_00744;MGYG000000217_00686;MGYG000002091_01028;MGYG000002194_01689;MGYG000000099_03199;MGYG000000194_03193;MGYG000002934_01311;MGYG000002845_01363;MGYG000002945_01502;MGYG000003583_00265;MGYG000000982_00638;MGYG000000133_02955;MGYG000003589_01762;MGYG000004634_00605;MGYG000002596_00549;MGYG000003142_00686;MGYG000000201_02673;MGYG000000251_01169;MGYG000004558_03187;MGYG000000153_02081;MGYG000001748_00979;MGYG000003821_02000;MGYG000004810_00381;MGYG000001338_02151;MGYG000000164_00358;MGYG000001356_00630;MGYG000002966_02744;MGYG000003656_02122;MGYG000000231_00504;MGYG000003432_00750 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.3125 186801|Clostridia 0.9583333333333334 G 1.0 Belongs to the PEP-utilizing enzyme family 0.7291666666666666 ppdK 0.9895833333333334 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9791666666666666 - 1.0 - 1.0 - 1.0 GT1 0.9583333333333334 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 15322117 15947122 8069399 13104146 15440742 14360621 11816614 14438851 12403133 14599870 14332606 16444696 12567218 13342117 19523828 13329003 12404819 37003827 11096534 16638700 16773826 12534844 35201681 8751980 19008478 12423424 12029167 30067516 16487426 16068151 6602567 12464599 6713901 16300579 12866323 11542396 15984616 8422338 9228146 20729610 4811656 6770031 7671798 4693566 7218786 8422204 6667753 6344518 5461457 8545428 5432363 5744181 4377035 3271641 5273025 17795673 5499945 7747384 6737930 3178253 10217873 7287843 6328940 5654441 7435780 14361113 9643144 6311618 20983702 10450304 5280731 8164363 8702527 8107157 6834779 6487818 16401655 22440588 12860267 12516277 9532888 9818784 12897715 13518977 12604726 12404096 12928621 15225896 12048987 15713650 16139331 14143847 16497896 10222303 14090887 12155634 15496257 13367665 15633482 9867381 15352049 12818497 16077999 10928889 12387217 17814583 14011438 20843986 18183676 13973400 8550908 12498474 14135522 13389138 7450695 26635232 8948558 6834179 14783831 7824801 6917466 5748919 6147839 7757605 9870555 10308619 10641638 6210787 6469700 9821575 8956453 11619346 4628103 7322612 7834141 7490704 7192692 9494124 5382816 4845542 6839526 14127096 16546089 7559444 21014255 16655206 10761410 4095555 5636762 7023164 5289567 11908230 16743705 39481799 23562525 22627792 9163546 9806589 22699706 15251496 12149854 17543257 16549396 17821810 11303925 22323533 17209521 16145215 13210678 12126260 15638093 7028513 18337458 13462061 21452256 9613376 14134774 20061714 17451425 24268501 21596565 5139748 24564627 35414907 32908526 15576347 11826488 15653180 8476914 16075913 -AALTADEVAK MGYG000002026_01365 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__HGM13010|s__HGM13010 sp900754965|m__MGYG000002026 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9191386 0 0 0 6860415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALTADR MGYG000002438_03578;MGYG000000236_00181;MGYG000001378_01176;MGYG000000044_00817;MGYG000001489_03803;MGYG000000013_03892;MGYG000000196_02017;MGYG000000222_00273;MGYG000001661_00974;MGYG000000696_02522;MGYG000001780_04079;MGYG000002549_01561;MGYG000001313_01473;MGYG000003681_00659;MGYG000002455_03526;MGYG000001346_03147;MGYG000003363_02147;MGYG000000098_03346;MGYG000001345_02795;MGYG000004763_00142 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 2721396 2475699 2213099 3459999 2837374 2131496 3180300 2482298 3058525 2658800 3042925 0 2455162 3211384 3137856 2665603 2609921 1393228 2917882 252749 0 2939232 2702882 3846639 3105497 3501996 3281852 1936168 3365779 4035576 3597935 3519789 3063371 5266325 4210376 3136355 3652026 2035231 3724872 2871114 3111194 5166572 3981352 4116178 3937627 5039533 3727354 4791364 4580910 5652700 3766847 5254687 6118761 3818458 4636054 1663563 5541654 5484648 0 4253164 0 4212310 4481729 5291562 4427783 1403825 3473151 4542581 3081181 3978003 2989471 5176278 3889438 5063534 5713858 3263482 1863003 2187630 2895226 2548581 3145079 3303217 2948226 1284158 3212247 3311651 3926587 3247762 2710801 3147903 536330 2643708 2187806 0 2264800 2555488 0 1811275 2598724 4024934 3004892 2919740 1017675 2006795 4248868 2887504 3575327 1972044 1032149 2213827 2636198 3233057 3060440 3083299 3393719 2893296 3325948 2785589 3022764 0 2739270 3028325 2532037 2540547 2155411 0 0 3096088 2386647 3164334 2948247 2900961 3550743 3098139 0 2491467 318996 4044769 2667923 3188821 2438266 1003634 2103635 3678137 4554360 3131444 2440863 4811160 3118640 1909093 3364330 4259490 2582058 1730282 1810685 2181745 3301469 2275295 2099278 1866812 2373378 2060235 4791159 2241518 3763847 1641423 2186663 1958779 1887325 3186245 2149312 3374459 0 2144075 2562995 3652415 3297386 3461736 2230021 1882975 1728969 2583675 2448174 3363273 1507741 2464160 3935292 2109360 3116231 1907114 -AALTAGDIAK MGYG000002274_02693;MGYG000002040_00906 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6489860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALTAGEIAK MGYG000004866_01031;MGYG000000022_02788;MGYG000001157_01952;MGYG000003899_02226;MGYG000003921_00033;MGYG000003166_00833;MGYG000000084_02524;MGYG000000636_01370;MGYG000002545_01217;MGYG000002138_00950;MGYG000002105_00879;MGYG000002224_02000;MGYG000001300_02837;MGYG000001255_00900;MGYG000004732_02304;MGYG000000039_02141 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 0.9375 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 15879569 14940597 14009059 9661172 0 0 0 0 0 13426359 0 0 0 0 0 0 26949003 0 15137821 0 0 19849464 0 0 0 10948460 22592941 0 0 0 0 0 0 10130601 0 11417793 0 21248984 15218651 16129741 0 0 13544483 19348327 0 0 0 0 0 0 0 0 0 15558878 13735906 20284958 0 0 0 13314242 0 0 0 0 13927951 0 0 0 0 0 0 0 0 0 0 0 7475413 0 8254447 0 6757340 7821345 6903940 8064878 0 9862082 10122030 7935172 8299966 0 7543979 6578837 18281764 0 0 9189702 7617699 18791233 0 0 7495908 8326641 18432348 0 0 0 7116811 6047281 0 0 7186398 8516285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5075204 0 0 0 0 0 0 2512846 0 0 3455859 0 0 3230543 17866147 0 0 0 4079368 21320014 0 0 0 0 22837648 4735103 0 0 0 0 2378242 0 0 0 0 -AALTANR MGYG000000243_00277;MGYG000001789_01569;MGYG000004797_01193;MGYG000003542_00399;MGYG000002218_01508;MGYG000001787_02320;MGYG000002478_03849 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 4042176 0 4040478 5534784 4517617 3537746 4420009 3384915 5135435 0 7041850 0 0 0 4644218 7679282 5220223 4304843 4891651 3662156 8633583 4029043 6262833 6016238 0 5139571 7424425 6171756 0 5301601 10140457 5516770 9068816 0 4850878 6055930 6187628 5887184 0 0 0 0 0 0 0 0 0 0 2791478 0 0 0 0 0 0 993566 0 0 0 0 2441781 0 0 0 0 2375130 0 0 9322221 0 0 0 21050431 0 0 0 461169 0 0 81594 7106958 6348590 0 414880 987185 0 5668698 0 0 0 83420 2605602 531825 331873 207422 631883 422847 450241 4600085 6835932 0 0 0 8032329 0 0 4227260 443973 434829 0 642713 6382796 1406488 557543 0 0 0 0 625935 0 427966 0 0 0 415835 0 0 0 70657 0 0 0 140068 0 259233 0 0 0 0 468048 121567 1639159 0 67852 0 0 0 0 0 83197 0 359254 0 0 469142 1485786 2386128 1646634 0 635748 2502057 0 1341110 0 0 0 0 2161299 1147347 4315129 1395470 1527550 0 1270163 2797352 1474045 0 2153959 0 1342915 0 431680 0 0 0 0 2942873 2117635 3348757 1095987 -AALTNMEGDPIAPAVAEAGER MGYG000001302.1_01910 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0526@1|root,COG0526@2|Bacteria,4NNXC@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 CO 1.0 Outer membrane protein Omp28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Cleaved_Adhesin,Omp28,Thioredoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 757263 1037856 721117 0 0 0 0 0 0 0 0 0 0 0 0 656224 1797390 0 0 0 740881 0 0 0 0 981177 0 0 0 0 755781 0 0 0 0 758689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 665859 554723 734449 0 0 0 0 0 0 0 0 0 0 0 0 976277 1026469 0 0 0 784931 0 0 0 0 847938 0 0 0 0 633520 0 0 0 0 724812 0 0 398092 0 381547 0 0 0 0 0 0 0 0 0 0 0 0 1039909 721252 0 0 0 1615985 0 0 0 0 1046319 0 0 0 0 383852 0 0 0 0 400855 0 0 0 429361 349984 0 0 0 0 0 0 0 0 0 0 0 0 696913 451571 0 0 0 710431 0 0 0 0 587242 0 0 0 0 0 0 0 0 0 0 -AALTSVMHR MGYG000002478_00538;MGYG000004797_03071 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4225@1|root,COG4289@1|root,COG4225@2|Bacteria,COG4289@2|Bacteria,4NEU3@976|Bacteroidetes,2G2NU@200643|Bacteroidia,4AKRX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 protein conserved in bacteria 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF2264,Glyco_hydro_88 1.0 3.2.1.- 1.0 GH105 1.0 GH105 1.0 GH105+GH154 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 962905 0 0 0 0 534179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALTVAISTIESASSK MGYG000002517_01116 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 195744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272379 0 0 0 0 315004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1882079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6950405 -AALVGLTK MGYG000000278_01407 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA3402|s__UBA3402 sp003478355|m__MGYG000000278 1.0 COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CYEK@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 IQ 1.0 Enoyl-(Acyl carrier protein) reductase 1.0 - 1.0 - 1.0 1.1.1.100 1.0 ko:K00059 1.0 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 1.0 M00083,M00572 1.0 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-oxoacyl-[acyl-carrier-protein] reductase. - Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates. a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH. 1.0 1.0 1.0 1.0 Biotin metabolism;Fatty acid metabolism;Fatty acid biosynthesis;Biosynthesis of unsaturated fatty acids;Metabolic pathways;Prodigiosin biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4189614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4521521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALVHGLK MGYG000002528_01864;MGYG000002756_00379;MGYG000002596_01649;MGYG000003215_00849;MGYG000004055_01475;MGYG000003500_00156;MGYG000004735_02050;MGYG000001141_01291;MGYG000002212_00566;MGYG000000164_02739;MGYG000003786_01019;MGYG000000204_02185;MGYG000001374_01171;MGYG000001689_04166;MGYG000002141_01720;MGYG000003486_01280;MGYG000001793_01089;MGYG000000078_01647;MGYG000004558_00350;MGYG000000278_00938;MGYG000002835_01005;MGYG000003442_01319;MGYG000004359_01015;MGYG000000139_02422;MGYG000001619_00808;MGYG000001493_03358;MGYG000000080_02280;MGYG000000028_01597;MGYG000004879_02709 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,25QPE@186804|Peptostreptococcaceae 0.27586206896551724 186801|Clostridia 1.0 J 0.7241379310344828 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.41379310344827586 rpsK 0.41379310344827586 - 1.0 - 1.0 ko:K02948 0.41379310344827586 ko03010,map03010 0.7241379310344828 M00178,M00179 0.7241379310344828 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.7241379310344828 - 1.0 - 1.0 - 0.7241379310344828 Ribosomal_S11 0.41379310344827586 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.7241379310344828 none 1.0 4069346 2457384 1650380 2196060 3391687 3551724 1558438 2623620 1893749 2266182 1750127 2048658 3565003 3416609 2945958 3535181 2284424 4438005 2727002 5581161 1959794 3680137 2517227 1225699 2743056 2126992 1999330 2468626 2036769 1985979 1004748 2120985 1100898 2956965 3262405 1857148 2963234 1961788 3698297 3383059 2493098 2578936 1723641 1962485 1820545 1966500 0 1830330 1521235 0 2221628 1754809 1346972 1618762 2581385 1622637 1666026 1907346 1361381 975069 1111212 2282742 1652053 1645278 1729926 1790385 3112355 1563784 2226277 1713396 2462981 3511568 3320421 3126611 0 2608668 3182294 5338043 0 3476479 1736013 3016591 2157975 3684392 2977536 3156329 2365560 1554375 3007740 3754398 3430152 3867487 4396068 1825437 3496842 3663504 4033649 6388695 2193912 2567641 0 1955456 4061565 2389531 4636448 3257635 1852968 4761040 3620813 4397569 2562761 3018030 3055867 3171803 5012193 2447251 2092294 4780713 2886333 2149086 3094662 5316139 6117103 3534510 2518549 2705216 2063687 5171975 4920458 2930547 4606827 1081497 3949282 5201107 2652130 1808515 426521 1755848 3257898 2558303 6316784 1084182 3050476 4373993 2102006 2235632 2263343 3086901 4660859 3732201 4311567 1960607 6551172 4309827 6462569 6977870 3511055 4743634 6385662 4888240 5491004 6921545 5896950 5978435 2895283 12782311 6867338 4645913 5419098 1535769 5179150 3511406 5756104 5338060 3120666 3504914 6303578 9244698 3923138 2006922 6257218 3718650 5124718 3081511 4453813 6352626 6737630 11833591 5862745 6593820 -AALVMSK MGYG000002517_00198 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2116378 0 0 2640052 0 0 0 0 0 0 2788977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALVNER MGYG000002478_03972 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1225@1|root,COG1225@2|Bacteria,4P08Q@976|Bacteroidetes,2FWN9@200643|Bacteroidia,4AKZE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Antioxidant, AhpC TSA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AhpC-TSA,DUF4369,Thioredoxin_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1628106 0 0 0 0 0 0 0 1613388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4740491 0 0 0 0 1209699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1771092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2924908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2664936 0 0 0 0 2775986 0 0 0 0 0 0 0 0 0 0 -AALVVMSEEK MGYG000000084_00622;MGYG000000245_02019 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3428180 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALVVVGDGK MGYG000001300_02197 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3WICZ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALWAASLR MGYG000003979_00338 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__CAG-272|g__UMGS1225|s__UMGS1225 sp900549725|m__MGYG000003979 1.0 COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,2203Z@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Pseudouridine synthase 1.0 - 1.0 - 1.0 5.4.99.23 1.0 ko:K06180 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03009 1.0 - 1.0 - 1.0 - 1.0 PseudoU_synth_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 23S rRNA pseudouridine(1911/1915/1917) synthase. - Pseudouridine synthase RluD converts uridines at positions 1911, 1915, and 1917 of 23S rRNA to pseudouridines.-!-These nucleotides are located in the functionally important helix- loop 69 of 23S rRNA. uridine(1911/1915/1917) in 23S rRNA = pseudouridine(1911/1915/1917) in 23S rRNA. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1380202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424125 0 0 0 -AALYDR MGYG000003683_00463;MGYG000002469_01094;MGYG000000756_00776;MGYG000001292_01123 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Belongs to the transketolase family 1.0 tkt 1.0 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA,Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4851012 0 0 0 0 2345342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1009715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALYDVADAISIVKK MGYG000000242_00769 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,21Z7M@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 160529 0 0 0 0 83817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287855 0 0 0 0 401493 0 0 0 0 496365 0 0 0 0 0 0 0 0 0 0 -AALYNK MGYG000000177_00821 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 2DM8R@1|root,32722@2|Bacteria,4P195@976|Bacteroidetes,2FPH0@200643|Bacteroidia,4AV5T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Mfa_like_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 983732 0 479177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 759552 0 832889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250830 0 500057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309740 0 311374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 514379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 536074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AALYYNNWQVAADASK MGYG000000243_02416 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1435@1|root,COG1435@2|Bacteria,4NFWU@976|Bacteroidetes,2FNY3@200643|Bacteroidia,4APFH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 895392 941863 2454718 1286043 959801 697612 1066629 0 896279 0 0 671360 0 0 521785 599324 0 0 0 0 856749 661486 0 767495 621718 699758 995913 0 0 907203 1967959 0 2915624 798081 0 874788 683736 2577687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 555733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310163 0 0 474779 376194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Carbamidomethyl)LAIMNPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Carbamidomethyl)LTIMNPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 122122 0 51438 0 0 0 0 138005 0 0 0 0 0 0 0 0 0 0 247181 0 0 0 0 0 289013 122998 103938 0 0 0 0 0 0 0 0 102727 202158 115191 223490 0 68919 0 0 0 0 80567 83178 0 0 0 0 0 0 0 0 0 78378 0 0 0 0 0 0 181625 202977 0 0 0 0 0 0 0 0 124012 0 74089 410146 0 172153 0 0 0 0 200430 200728 0 0 0 0 0 0 0 0 0 160983 0 0 0 0 0 678220 476395 643026 0 0 0 0 0 146222 0 0 0 181912 0 162247 0 0 0 0 0 0 952626 390268 0 0 0 0 0 0 0 0 0 573779 0 0 0 0 0 614896 335508 396762 0 0 0 0 0 0 0 0 134135 729517 0 302679 0 631170 0 0 0 0 228303 579290 0 0 0 0 0 0 0 0 0 302375 0 0 0 0 0 612300 521314 343143 0 0 0 491856 0 705240 0 0 597885 629361 548246 -AAM(Met->Glu)LTIMNPDDK MGYG000000077_02468;MGYG000002278_01894;MGYG000004740_00274;MGYG000000087_01268;MGYG000001809_02343;MGYG000000255_01557;MGYG000002517_00543;MGYG000000154_01281;MGYG000000262_02235 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae 0.3333333333333333 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.3333333333333333 etfB 1.0 - 0.6666666666666666 - 0.6666666666666666 ko:K03521 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.6666666666666666 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 654147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1255152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Met->Xle)AGFADVPGTR MGYG000000179_01101;MGYG000000133_01756;MGYG000000194_02287;MGYG000000242_00749;MGYG000004747_00336;MGYG000001619_02391;MGYG000000255_01003;MGYG000001602_01322;MGYG000000205_02361;MGYG000004087_00427 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,21ZGH@1506553|Lachnoclostridium 0.6 186801|Clostridia 1.0 E 1.0 Threonine synthase 0.6 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 634259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1109038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)AAAEGDYK MGYG000001562_00661;MGYG000000003_00454;MGYG000003279_00196 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476971 0 0 0 0 0 0 0 0 0 0 303667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)ADVLK MGYG000002494_04522 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria,3XN36@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) 1.0 luxS 1.0 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 1.0 4.4.1.21 1.0 ko:K07173 1.0 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 1.0 M00609 1.0 R01291 1.0 RC00069,RC01929 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 1.0 LuxS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 S-ribosylhomocysteine lyase. S-ribosylhomocysteinase. The 4,5-dihydroxypentan-2,3-dione formed spontaneously cyclizes and combines with borate to form an autoinducer (AI-2) in the bacterial quorum-sensing mechanism, which is used by many bacteria to control gene expression in response to cell density.-!-Formerly EC 3.2.1.148 and EC 3.3.1.3. S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3- dione + L-homocysteine. 1.0 1.0 1.0 1.0 Biofilm formation - Vibrio cholerae;Biofilm formation - Escherichia coli;Cysteine and methionine metabolism;Metabolic pathways;Quorum sensing;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 709754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1073203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211677 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 827749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1144833 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)AEKTELSKK MGYG000002517_00455 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia 1.0 186801|Clostridia 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hup 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 138450 0 0 0 0 0 0 41635 89877 0 0 0 0 0 0 0 357132 0 116932 0 0 0 0 0 0 77980 102762 0 0 0 0 0 0 0 0 0 103975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 57259 0 0 0 0 0 0 0 0 0 0 0 0 0 64827 0 0 0 0 0 0 0 0 0 158197 0 244017 0 0 0 0 0 0 463489 467968 0 0 0 78671 0 0 0 177384 0 221928 0 0 0 0 0 458245 529907 331139 0 0 0 0 0 0 0 0 0 448584 0 284392 0 0 0 0 0 0 94363 243798 0 0 0 1321198 0 0 0 256736 0 265640 0 0 0 0 0 489315 392821 554120 0 0 0 0 0 0 0 0 0 892412 0 -AAM(Oxidation)AGEEVK MGYG000002279_01083;MGYG000002992_00602;MGYG000000038_01566 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG0252@1|root,COG5275@1|root,COG0252@2|Bacteria,COG5275@2|Bacteria,1TQ9S@1239|Firmicutes,24A9Y@186801|Clostridia,27WDD@189330|Dorea 1.0 186801|Clostridia 1.0 EJ 1.0 Glycine/sarcosine/betaine reductase component B subunits 1.0 prdA 1.0 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114 1.0 1.21.4.1 1.0 ko:K10793 1.0 ko00330,map00330 1.0 - 1.0 R02825 1.0 RC00790 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 D-proline reductase. - A pyruvoyl- and L-selenocysteine-containing enzyme found in a number of Clostridial species.-!-The pyruvoyl group, located on the PrdA subunit, binds the substrate, while the selenocysteine residue, located on the PrdB subunit, attacks the alpha-C-atom of D-proline, leading to a reductive cleavage of the C-N-bond of the pyrrolidine ring and formation of a selenoether.-!-The selenoether is cleaved by a cysteine residue of PrdB, resulting in a mixed selenide-sulfide bridge, which is restored to its reduced state by another selenocysteine protein, PrdC.-!-5-aminopentanoate is released from PrdA by hydrolysis, regenerating the pyruvoyl moiety.-!-The resulting mixed selenide-sulfide bridge in PrdC is reduced by NADH.-!-Formerly EC 1.4.1.6 and EC 1.4.4.1. 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine = [PrdC protein]-L-selenocysteine/L-cysteine + D-proline. 1.0 1.0 1.0 1.0 Arginine and proline metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 703716 1084981 949968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232381 0 0 0 0 0 207368 477520 315251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)AGFADVPGTR MGYG000000179_01101;MGYG000000133_01756;MGYG000000194_02287;MGYG000000242_00749;MGYG000004747_00336;MGYG000001619_02391;MGYG000000255_01003;MGYG000001602_01322;MGYG000000205_02361;MGYG000004087_00427 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,21ZGH@1506553|Lachnoclostridium 0.6 186801|Clostridia 1.0 E 1.0 Threonine synthase 0.6 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 463809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170650 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 840420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)ATITNHDDLAAVEAALR MGYG000000099_01611 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,26915@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 649740 0 0 802438 0 0 0 788719 0 615979 0 0 0 580110 0 0 0 0 0 0 0 0 0 0 0 603881 0 0 0 890314 0 0 0 0 727168 0 730111 0 0 0 0 0 0 0 0 186993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212218 0 0 0 0 192731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)AVANM(Oxidation)R MGYG000002478_00968;MGYG000000243_02351 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409433 0 0 0 0 169136 0 0 0 0 227798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 61764 0 0 0 0 73137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77278 0 0 0 0 66489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)DTDDKNVR MGYG000002545_02040;MGYG000002223_00474;MGYG000004487_01385;MGYG000000039_01246;MGYG000002143_00092;MGYG000001300_01096;MGYG000002610_00641;MGYG000004791_00484;MGYG000000099_02658;MGYG000000739_01736;MGYG000004482_00415;MGYG000003819_01815;MGYG000003291_01172;MGYG000000022_00767;MGYG000004784_01270;MGYG000004475_00794;MGYG000001255_01028;MGYG000002105_01011;MGYG000002272_02459;MGYG000002926_00921;MGYG000000195_00123;MGYG000002040_01360;MGYG000002057_00134;MGYG000001616_01899;MGYG000004525_02384;MGYG000001225_01335 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.9615384615384616 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 86868 99021 0 232708 0 152886 170032 0 104047 0 0 79209 0 0 0 0 0 614644 0 219892 0 256016 222505 157991 0 143095 0 257737 0 0 0 151731 0 0 0 0 50654 0 136840 146198 0 359489 0 78436 321069 0 617320 0 0 266192 0 0 0 0 0 94561 0 259005 0 0 0 171836 0 173418 0 112681 0 0 0 0 0 0 0 0 288724 0 0 264202 0 195973 0 92336 89016 0 46444 0 0 87063 0 0 0 0 0 50997 0 152279 0 99726 64336 0 0 0 0 155954 0 0 0 81388 0 0 0 0 112183 0 133271 113907 0 0 0 211133 234663 0 128498 0 0 182970 0 0 0 0 0 176676 0 135281 0 218100 0 213404 0 128652 0 391791 0 0 0 201570 0 0 0 0 112071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42327 0 0 0 0 225323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)GNFAAFSAIPGVEVR MGYG000002274_00295;MGYG000002641_00490;MGYG000001300_00512 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 451438 0 0 0 0 619291 0 0 0 0 764575 0 0 0 0 0 0 0 0 0 299707 0 0 516275 0 0 0 0 0 973919 0 0 0 0 0 0 0 0 2264058 0 0 0 0 2326919 0 0 0 0 2429556 0 0 0 0 0 0 0 732786 0 943407 0 0 237462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739864 0 0 0 0 953206 0 0 0 0 822841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599217 0 0 0 0 0 0 0 0 0 110015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385407 0 0 0 0 314484 0 0 0 0 265169 0 0 0 0 0 0 0 97746 0 0 -AAM(Oxidation)GNFASFEAIPGIEVR MGYG000004271_00710;MGYG000000271_01845 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)GNFASFSAIPGVEVR MGYG000000022_00672 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 661963 0 0 0 0 1502502 0 0 0 0 1238305 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)IQNHQIGLSGGTEK MGYG000002438_03064 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22XE6@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)KEASEGELK MGYG000004468_00660;MGYG000000044_01948;MGYG000001749_01249;MGYG000001783_01519;MGYG000001546_00360;MGYG000001489_03093;MGYG000004006_01717;MGYG000002007_00386;MGYG000004756_01346;MGYG000003202_00946;MGYG000003681_00790;MGYG000001345_01069;MGYG000002438_00285;MGYG000003514_00715;MGYG000000003_00712;MGYG000000196_00479;MGYG000001562_00044;MGYG000004464_00783;MGYG000001661_02632;MGYG000001313_02393;MGYG000002549_00455;MGYG000001415_02219;MGYG000001337_01464;MGYG000002737_00455;MGYG000004536_01441;MGYG000001789_00244;MGYG000000273_02725;MGYG000000053_01377;MGYG000002281_04045;MGYG000000478_01407 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.43333333333333335 976|Bacteroidetes 0.9 G 0.5333333333333333 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.9666666666666667 gap 0.9666666666666667 - 0.9333333333333333 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 486186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)LAIM(Oxidation)NPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 777805 0 0 0 0 0 0 0 0 0 0 0 644786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258994 0 0 0 0 0 0 0 0 0 0 0 621891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307795 0 0 0 0 0 0 0 0 0 0 0 306241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)LAIMNPDDK MGYG000004719_02002;MGYG000001637_02230;MGYG000000271_02101;MGYG000001315_01867;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8333333333333334 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 506370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)LAIMNPDDKA MGYG000004762_01002 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Catenibacillus|s__Catenibacillus sp900553975|m__MGYG000004762 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1381762 0 0 0 0 1457300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)LAIMNPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 626951 0 0 1443829 894872 0 1067383 0 426123 0 0 1023352 0 0 0 1257259 1299764 249538 0 690565 1313011 473477 0 0 0 640229 0 0 0 1207581 0 0 764800 0 0 674677 1634546 0 0 0 0 0 0 0 0 0 253950 847633 0 0 0 0 0 0 595877 0 0 0 535859 0 0 0 0 0 0 0 951003 1267835 0 0 0 0 0 0 0 0 295006 0 0 0 0 0 0 0 252774 0 0 686781 0 0 0 0 461898 0 0 0 0 0 0 0 0 598082 0 0 0 0 0 0 0 0 0 0 0 0 278884 0 0 0 0 0 0 0 171459 0 0 259706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830921 0 0 0 0 0 0 0 0 182221 370151 188556 571753 0 567820 0 278909 473839 0 0 625692 704640 0 1002489 0 0 0 0 655645 0 0 415225 623651 0 138111 705387 0 514657 668432 275296 0 594943 0 0 551816 0 0 609927 582280 477374 -AAM(Oxidation)LTIM(Oxidation)NPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 991989 840465 480006 1032091 818034 608022 349359 1038769 1027899 1224685 635745 687518 501301 661291 1026803 894632 1440905 0 1249527 844809 916065 1304642 0 483714 979787 761977 867763 0 302980 596481 351439 767226 329639 863623 637041 587927 620419 0 386064 555088 180437 484271 295797 237321 625685 412872 878740 252363 427211 323838 434001 233688 394060 277248 291720 0 420438 511997 314057 90265 0 522148 235940 319169 299485 0 312781 298819 113372 303500 358769 772195 507118 520901 443660 320590 1702782 2384416 408457 2415978 282859 904254 799602 1422127 561067 1470733 698593 1010438 1173498 1047260 1336308 1055026 1033990 0 1296522 1283916 995191 1658553 0 885337 1286698 1692588 1197543 0 359782 834007 452683 1275481 668863 1246239 1457635 562618 920786 399380 2627342 951718 919058 2423707 1451983 1195437 1645143 3164401 2837985 1752927 1004866 1624672 1232276 3339284 3479748 1421480 2345236 0 2587677 2292008 2252807 550068 0 275421 3100513 2604142 2312708 0 881372 2280810 689528 1076810 948538 1774418 2678350 2110223 2990849 657542 1116906 1664296 2206101 331569 1072681 2136556 1574503 1581285 1370096 2310248 1173291 1636132 755429 1780989 2642668 1573722 1729847 0 1672515 887983 1766291 1551440 0 1533972 1600157 1883976 1670069 0 538734 895995 1143561 456105 1807110 1163272 1002695 1428508 1588359 1349153 -AAM(Oxidation)LTIMN(Deamidated)PDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 0 0 0 0 0 0 0 251339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227968 0 143341 0 0 0 0 0 0 237776 363438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250027 0 0 0 0 0 0 0 0 0 0 0 116488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410201 0 0 0 0 0 0 996987 1037629 0 0 0 0 1093172 0 0 0 0 0 0 0 0 0 0 0 1540361 0 0 0 0 0 0 0 0 934064 0 858130 0 634558 0 0 0 0 0 0 0 0 0 0 0 0 447976 0 0 0 0 0 0 0 0 0 0 0 1330799 0 0 0 0 0 0 0 0 969996 0 1154511 0 -AAM(Oxidation)LTIMNPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 1000006 1167170 732597 1323129 1185495 1057836 688950 1500490 908040 1840097 870356 1048189 1060647 719945 1407867 1366607 1962686 0 1639877 1298375 1245566 1979563 0 607647 1210126 1060208 1121926 0 0 935411 574271 628218 561596 949047 1116698 710654 738430 507838 606459 348027 483749 704157 796779 415561 1164535 1077450 1457767 851373 587805 446155 430455 929441 841936 343614 738927 0 818726 901762 688209 355773 0 766195 242142 706386 791027 0 0 563944 820701 619559 358947 898656 695034 836974 922558 539715 2287388 4258790 637426 3475480 278815 1371521 937979 2048370 930312 2625944 721008 1902878 1216209 1837968 2041110 1181319 1818264 0 2942278 2104172 1380362 2418554 0 848928 2017950 2012437 2722386 0 0 1419721 450464 1513463 1143994 2256660 2512418 788498 1518251 623504 4089647 1184292 752258 3387160 1687116 1601875 2059820 4105478 3680754 2090802 1353185 2079555 1416431 4363837 4442183 2073264 2480661 0 2657598 3638100 2851919 759553 0 458246 3589552 4517449 2908803 0 0 2940974 1017965 1367291 1195137 2790391 2909511 2493916 4243536 664044 1656180 1963279 3805638 0 1364233 2247008 2201056 1887014 1859553 3281927 4337808 2325156 1135639 5252619 3078871 2158065 2486552 0 2575990 1093735 1897867 1524104 0 2623978 3067408 2089782 2963342 0 0 818639 1997275 1040018 2801993 1987459 1989684 2963768 2434191 2463478 -AAM(Oxidation)PEAGPVILEPIHTLK MGYG000002274_01087;MGYG000001255_02150;MGYG000003899_02100;MGYG000002641_01949;MGYG000002040_00027;MGYG000004679_00212;MGYG000002272_00718;MGYG000002545_01805;MGYG000001300_02656;MGYG000003291_01552 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 translation elongation 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 583995 0 0 0 0 223183 0 0 0 0 109882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 430899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306755 0 0 0 0 2979585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAM(Oxidation)TVSISDMTVPAQK MGYG000004884_01728 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__KLE1615|s__|m__MGYG000004884 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,27IYQ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1329859 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMAAAEGDYK MGYG000001562_00661;MGYG000000003_00454;MGYG000003279_00196 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1977517 2882552 1626126 3259922 1644257 2645485 2024181 997685 2202042 2838798 915156 3594891 1788350 2155586 2598563 1748476 2170883 0 2667099 2524860 2449668 1983510 0 4095920 2251836 2596921 3286528 0 2338909 3619481 1852800 2477449 1849771 819427 1884213 3235139 2475410 1109073 568083 380801 769285 890344 710753 628189 367168 430075 639482 699340 453356 932147 569740 863070 1059605 754989 831668 0 538691 653971 631469 640959 0 613546 798668 856272 868878 0 536243 995497 527382 656789 697645 0 542918 496255 785426 823506 4032286 1460248 3484664 3194319 3832486 1852573 3550080 3000160 4891510 3198874 2045837 2994872 2120007 3630247 3032537 1775839 2154822 0 2931272 3070976 4355047 1590674 0 1894776 2790888 3952036 2919774 0 2670768 3312558 1754451 1384337 2147404 3657782 1739322 5122170 3217304 3317752 732726 733897 1090079 602699 762811 570628 683520 890789 535297 739295 217957 1369391 1308453 788933 968196 614907 698564 0 706079 766506 968969 199577 0 341354 1260239 1708874 942356 0 981691 1137417 1057897 1117079 1124319 1035311 863568 1038003 1018025 684140 421124 287286 0 407210 145925 0 334493 326515 229422 0 144584 198464 0 0 0 253962 311056 0 0 387557 290189 0 0 0 432500 478143 0 0 0 527244 0 0 189629 511198 0 0 237608 0 -AAMADVLK MGYG000002494_04522 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria,3XN36@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) 1.0 luxS 1.0 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 1.0 4.4.1.21 1.0 ko:K07173 1.0 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 1.0 M00609 1.0 R01291 1.0 RC00069,RC01929 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 1.0 LuxS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 S-ribosylhomocysteine lyase. S-ribosylhomocysteinase. The 4,5-dihydroxypentan-2,3-dione formed spontaneously cyclizes and combines with borate to form an autoinducer (AI-2) in the bacterial quorum-sensing mechanism, which is used by many bacteria to control gene expression in response to cell density.-!-Formerly EC 3.2.1.148 and EC 3.3.1.3. S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3- dione + L-homocysteine. 1.0 1.0 1.0 1.0 Biofilm formation - Vibrio cholerae;Biofilm formation - Escherichia coli;Cysteine and methionine metabolism;Metabolic pathways;Quorum sensing;Biosynthesis of amino acids 1.0 none 1.0 0 629363 304596 0 0 0 410319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053093 0 895274 1327950 0 0 0 0 0 0 732641 713064 0 0 0 0 1058068 0 5787904 5281006 0 0 10453981 4107541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8765544 4222337 0 0 0 0 0 0 3593016 0 0 0 0 0 4734774 0 116164 0 0 0 404544 134074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289605 0 472263 341872 0 0 0 0 0 0 202556 169809 0 0 0 0 206897 0 0 0 0 0 324386 593169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421710 0 321947 577365 0 0 0 0 0 0 228033 331136 0 0 0 0 237699 0 0 0 0 0 946502 956876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 748435 0 754558 858768 0 0 0 0 0 0 0 614145 0 0 0 0 663446 -AAMAEKTELSK MGYG000002517_00455 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia 1.0 186801|Clostridia 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hup 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158712 0 0 0 0 0 0 0 0 0 68207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167038 0 0 0 0 0 0 0 0 0 125082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1002606 0 0 0 0 0 0 0 0 0 724290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 889290 0 0 0 0 0 0 0 0 0 673338 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMAEKTELSKK MGYG000002517_00455 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia 1.0 186801|Clostridia 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hup 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 939074 232458 276652 0 455157 350092 0 790888 423934 1007053 0 268942 193003 0 802815 0 1478760 0 1009698 211986 0 290355 0 308506 315730 723112 0 0 0 0 0 0 430676 365987 1063709 597513 752794 183588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190136 0 0 0 182008 0 0 593871 497286 423926 0 432321 353840 0 394375 0 192283 0 653301 370991 0 0 0 0 707058 965337 0 0 0 0 0 0 0 371464 477820 503163 1058141 0 1276758 206099 0 0 265945 341197 0 2281759 1401450 276364 0 1154901 493785 0 2431582 0 532181 0 1274798 885743 0 155912 0 0 2837575 2850076 0 0 0 0 0 0 158658 2975118 1866580 1261305 2044803 143278 2849821 953791 1896371 0 1418830 1759528 0 924892 1957321 3585116 0 1649437 4847593 0 3451417 0 1992150 0 2406129 2059866 0 120034 0 1636832 1758469 2586772 0 0 0 0 0 0 2006557 2195951 2870390 2841859 3630690 1747003 -AAMAGEEVK MGYG000002279_01083;MGYG000002992_00602;MGYG000000038_01566 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG0252@1|root,COG5275@1|root,COG0252@2|Bacteria,COG5275@2|Bacteria,1TQ9S@1239|Firmicutes,24A9Y@186801|Clostridia,27WDD@189330|Dorea 1.0 186801|Clostridia 1.0 EJ 1.0 Glycine/sarcosine/betaine reductase component B subunits 1.0 prdA 1.0 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114 1.0 1.21.4.1 1.0 ko:K10793 1.0 ko00330,map00330 1.0 - 1.0 R02825 1.0 RC00790 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 D-proline reductase. - A pyruvoyl- and L-selenocysteine-containing enzyme found in a number of Clostridial species.-!-The pyruvoyl group, located on the PrdA subunit, binds the substrate, while the selenocysteine residue, located on the PrdB subunit, attacks the alpha-C-atom of D-proline, leading to a reductive cleavage of the C-N-bond of the pyrrolidine ring and formation of a selenoether.-!-The selenoether is cleaved by a cysteine residue of PrdB, resulting in a mixed selenide-sulfide bridge, which is restored to its reduced state by another selenocysteine protein, PrdC.-!-5-aminopentanoate is released from PrdA by hydrolysis, regenerating the pyruvoyl moiety.-!-The resulting mixed selenide-sulfide bridge in PrdC is reduced by NADH.-!-Formerly EC 1.4.1.6 and EC 1.4.4.1. 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine = [PrdC protein]-L-selenocysteine/L-cysteine + D-proline. 1.0 1.0 1.0 1.0 Arginine and proline metabolism 1.0 none 1.0 5865523 3846888 3870978 3144485 0 3608046 0 5191157 3494192 4411667 3391788 4266055 5062244 4903513 6933275 513930 270541 0 5917942 5582653 4998430 4235965 0 1933839 6534368 4115928 3902971 0 3827752 2767342 0 2513201 416109 3121972 5514948 3468943 3486017 3340481 2774338 1081891 114908 3908350 0 339796 0 2981252 1040279 1133702 254862 415532 491468 1428009 2300094 0 0 0 2746757 3536516 1597526 0 0 2246508 2468206 2718889 1473815 0 4751343 1712239 0 152788 0 4100301 1997003 3179312 3092118 0 5101567 4923816 2459146 2863699 0 1264405 0 6676889 3173962 5802523 1844233 2866120 4472656 4998333 6592105 4887895 4924328 0 7130213 9401195 4904081 5060543 0 431557 7001804 4928804 5598458 0 4558839 5695721 0 5509588 6124713 6465575 6568653 4064020 3318009 2371978 2561085 2006326 575699 2725951 0 338360 0 3149775 235160 2998153 2419468 2295036 2498629 1702617 2453807 301122 1827057 0 3923235 1479704 2106193 715495 0 2715698 3113059 2591146 1813670 0 548464 2856405 0 2495051 406135 4262400 2901841 2692039 2363289 894588 0 0 0 0 0 0 0 0 0 0 272371 0 0 0 0 0 0 0 355610 907973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMAGEEVKAAEK MGYG000002279_01083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena_B|m__MGYG000002279 1.0 COG0252@1|root,COG5275@1|root,COG0252@2|Bacteria,COG5275@2|Bacteria,1TQ9S@1239|Firmicutes,24A9Y@186801|Clostridia,27WDD@189330|Dorea 1.0 186801|Clostridia 1.0 EJ 1.0 Glycine/sarcosine/betaine reductase component B subunits 1.0 prdA 1.0 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114 1.0 1.21.4.1 1.0 ko:K10793 1.0 ko00330,map00330 1.0 - 1.0 R02825 1.0 RC00790 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 D-proline reductase. - A pyruvoyl- and L-selenocysteine-containing enzyme found in a number of Clostridial species.-!-The pyruvoyl group, located on the PrdA subunit, binds the substrate, while the selenocysteine residue, located on the PrdB subunit, attacks the alpha-C-atom of D-proline, leading to a reductive cleavage of the C-N-bond of the pyrrolidine ring and formation of a selenoether.-!-The selenoether is cleaved by a cysteine residue of PrdB, resulting in a mixed selenide-sulfide bridge, which is restored to its reduced state by another selenocysteine protein, PrdC.-!-5-aminopentanoate is released from PrdA by hydrolysis, regenerating the pyruvoyl moiety.-!-The resulting mixed selenide-sulfide bridge in PrdC is reduced by NADH.-!-Formerly EC 1.4.1.6 and EC 1.4.4.1. 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine = [PrdC protein]-L-selenocysteine/L-cysteine + D-proline. 1.0 1.0 1.0 1.0 Arginine and proline metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMAGEEVKAAEKK MGYG000002279_01083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena_B|m__MGYG000002279 1.0 COG0252@1|root,COG5275@1|root,COG0252@2|Bacteria,COG5275@2|Bacteria,1TQ9S@1239|Firmicutes,24A9Y@186801|Clostridia,27WDD@189330|Dorea 1.0 186801|Clostridia 1.0 EJ 1.0 Glycine/sarcosine/betaine reductase component B subunits 1.0 prdA 1.0 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114 1.0 1.21.4.1 1.0 ko:K10793 1.0 ko00330,map00330 1.0 - 1.0 R02825 1.0 RC00790 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 D-proline reductase. - A pyruvoyl- and L-selenocysteine-containing enzyme found in a number of Clostridial species.-!-The pyruvoyl group, located on the PrdA subunit, binds the substrate, while the selenocysteine residue, located on the PrdB subunit, attacks the alpha-C-atom of D-proline, leading to a reductive cleavage of the C-N-bond of the pyrrolidine ring and formation of a selenoether.-!-The selenoether is cleaved by a cysteine residue of PrdB, resulting in a mixed selenide-sulfide bridge, which is restored to its reduced state by another selenocysteine protein, PrdC.-!-5-aminopentanoate is released from PrdA by hydrolysis, regenerating the pyruvoyl moiety.-!-The resulting mixed selenide-sulfide bridge in PrdC is reduced by NADH.-!-Formerly EC 1.4.1.6 and EC 1.4.4.1. 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine = [PrdC protein]-L-selenocysteine/L-cysteine + D-proline. 1.0 1.0 1.0 1.0 Arginine and proline metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMAGFADVPGTK MGYG000004296_00212;MGYG000001338_02004;MGYG000000142_03243 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3XZ3J@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 8.87 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264914 971352 0 0 0 0 0 0 0 0 395703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2340154 1229247 929283 0 0 0 0 1191768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1403809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1702477 1334462 496135 0 0 0 0 0 0 0 902911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 959531 0 1573087 0 0 0 0 724092 -AAMAGFADVPGTR MGYG000000179_01101;MGYG000000133_01756;MGYG000000194_02287;MGYG000000242_00749;MGYG000004747_00336;MGYG000001619_02391;MGYG000000255_01003;MGYG000001602_01322;MGYG000000205_02361;MGYG000004087_00427 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,21ZGH@1506553|Lachnoclostridium 0.6 186801|Clostridia 1.0 E 1.0 Threonine synthase 0.6 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 493420 0 0 449495 0 349614 0 0 0 0 309839 0 395973 570157 774016 558084 0 471400 0 0 680828 0 783393 289821 0 633843 384802 502874 604804 0 0 253908 0 0 0 749404 534974 0 0 0 0 442921 0 0 0 0 0 0 258168 0 263581 268902 303161 0 0 646838 0 0 156709 0 302935 0 0 169866 0 512631 288108 0 0 0 0 0 0 0 0 0 517039 0 0 516253 0 264846 0 0 0 0 510271 0 382524 456605 635118 542633 0 0 0 0 620851 547111 282332 0 0 427300 811080 0 553539 0 0 451907 0 0 0 437257 582931 0 0 0 0 226369 0 304095 0 0 0 0 581982 0 461747 381787 1139274 376034 0 0 0 0 0 639362 362416 315187 0 0 429943 2517870 504632 0 0 337333 0 0 0 748573 264150 0 2381391 0 0 3041325 0 1400121 0 0 0 0 1763134 0 1164795 3216639 2534508 1727802 0 358196 0 0 2853434 1357556 619385 2156749 0 2177143 2771721 596041 3258642 0 0 2585137 0 0 0 2767636 1885487 0 -AAMAGFADVPGTR(Arg->Lys) MGYG000000179_01101;MGYG000000133_01756;MGYG000000194_02287;MGYG000000242_00749;MGYG000004747_00336;MGYG000001619_02391;MGYG000000255_01003;MGYG000001602_01322;MGYG000000205_02361;MGYG000004087_00427 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,21ZGH@1506553|Lachnoclostridium 0.6 186801|Clostridia 1.0 E 1.0 Threonine synthase 0.6 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Metabolic pathways;Vitamin B6 metabolism;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1673939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMALQTDPR MGYG000000195_01287;MGYG000002040_00215;MGYG000000022_01148;MGYG000001300_00107;MGYG000002641_00333;MGYG000002274_00742 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WGM4@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 1.0 L 0.6666666666666666 that it carries out the mismatch recognition step. This protein has a weak ATPase activity 0.6666666666666666 mutS 0.6666666666666666 - 1.0 - 1.0 ko:K03555 0.6666666666666666 ko03430,map03430 0.6666666666666666 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03400 0.6666666666666666 - 1.0 - 1.0 - 1.0 MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Mismatch repair 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2166394 1374683 0 0 0 3694258 0 0 0 0 2631293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1538194 1544691 0 0 0 2206738 0 1766011 0 0 1916125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5879719 4589330 0 0 0 1538477 0 5014679 0 0 5362054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1091607 5520303 0 0 0 944971 0 8686588 0 0 9840931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6070611 0 0 0 0 5429699 0 5044965 0 0 4767307 0 0 0 0 0 0 0 0 0 0 -AAMATITNHDDLAAVEAALR MGYG000000099_01611 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,26915@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 190956 409185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185163 174889 0 0 0 0 3204028 0 1857339 4279766 2534639 1906079 3931689 4366392 2747611 3382833 2314641 2811127 1434992 4486437 6068119 1964367 3465126 0 2614279 4234585 3052858 1848601 0 1847076 2748365 4479765 3873712 0 4322564 3028992 0 3081537 1677683 4042396 3460213 3092602 3351222 1516857 334462 0 339631 0 0 0 503833 365836 224256 420345 264416 0 107998 469085 493395 109877 433448 0 348999 0 0 118538 0 0 324574 0 140326 0 195532 134668 0 413229 0 415965 181774 343480 149978 0 386101 0 192581 0 301773 161282 293732 0 0 103056 181561 0 660912 116921 0 229641 186072 0 0 130309 346771 196735 0 217331 253491 215965 209518 0 227470 177513 0 212688 193226 246867 138628 142125 155387 212319 0 0 0 0 0 0 0 0 0 0 153077 0 313940 0 0 0 423615 0 282003 0 0 0 0 0 119746 0 0 0 0 0 0 0 0 0 114694 0 0 0 -AAMAV(Val->Thr)YSEEGK MGYG000004764_00548 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA2856|s__UBA2856 sp900555005|m__MGYG000004764 1.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate 1.0 dapL 1.0 - 1.0 2.6.1.83 1.0 ko:K10206 1.0 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 1.0 M00527 1.0 R07613 1.0 RC00006,RC01847 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 LL-diaminopimelate aminotransferase. LL-diaminopimelate transaminase. In vivo, the reaction occurs in the opposite direction to that shown above.-!-This is one of the final steps in the lysine biosynthesis pathway of plants (ranging from mosses to flowering plants).-!-Meso-diaminoheptanedioate, an isomer of LL-2,6-diaminoheptanedioate, and the structurally related compounds lysine and ornithine are not substrates.-!-2-oxoglutarate cannot be replaced by oxaloacetate or pyruvate.-!-It is not yet known if the substrate of the biosynthetic reaction is the cyclic or acyclic form of tetrahydropyridine-2,6-dicarboxylate. (2S,6S)-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5- tetrahydrodipicolinate + H(+) + H2O + L-glutamate. 1.0 1.0 1.0 1.0 Lysine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1273060 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMAVANM(Oxidation)R MGYG000002478_00968;MGYG000000243_02351 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMAVANMR MGYG000002478_00968;MGYG000000243_02351 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 2517615 0 3234563 2881092 3228950 2652793 2387559 2111498 3468267 2169404 2271408 2089170 3215227 3546525 3674658 2979103 2336592 2285661 2621148 2461435 2465728 2039882 2557650 2365643 2125208 2237085 2536424 1917562 2184206 2315165 3764827 2689742 3834203 2204865 2916929 2299086 2325451 3505230 1336095 0 1401544 1350374 1414495 1001942 1268960 1386860 1029374 1559723 1030512 969483 1429669 1434909 1366748 1494446 1134443 1618700 1438953 1287352 1203284 1190302 1721241 877849 1260521 1229493 1271520 1584853 1274154 1318969 940219 1001721 1133508 1189938 1510646 1329916 1307291 1201955 1828350 0 1817215 1613804 2254820 1575968 2047292 1400272 1757870 1833162 1394187 1411679 1759619 1490012 1209734 2043247 877683 2269049 1521494 1465505 1162777 1157066 2280087 1705342 1685436 1455811 1456578 1803294 1751316 1327906 1564667 1345419 1205148 1002280 1768716 1918576 1536825 1748959 1514072 0 1570690 1708353 1186755 1513378 538185 1451194 1651536 1521164 1169073 962843 0 1207200 1541851 955735 1147046 1769243 1223951 1218831 824823 929245 559918 972890 2043695 928401 816548 1020535 1524155 0 177887 1598110 1468167 1475610 1355907 770753 1481061 1538536 2376061 0 1565918 1719044 2203044 2232907 2504104 2345783 1978424 1473658 1742602 1751060 2108663 1655370 1737213 2813214 1936787 3581950 2687815 2484629 1446022 2047422 3253281 1470601 1805932 2995847 1916628 2989297 2366974 2156261 1779839 1998144 1694132 2144605 1994583 2313026 1887071 1836567 -AAMDAAHGIEYSTVVTTMAR MGYG000002506_04541 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1304@1|root,COG1304@2|Bacteria,1QWBP@1224|Proteobacteria,1T2T0@1236|Gammaproteobacteria,3XN3J@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Protein of unknown function (DUF1116) 1.0 yahG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1116 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 1531588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311593 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2424646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1398876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 798987 0 0 0 0 -AAMDDGNEVAK MGYG000000562_00657 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp000437735|m__MGYG000000562 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,267UV@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288298 0 0 0 0 0 0 0 0 0 136864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 951543 0 0 0 0 756168 0 0 0 0 179997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMDELLDDPVKNYLK MGYG000003166_00812;MGYG000001300_02509;MGYG000003291_01565 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth 1.0 sigA 1.0 - 1.0 - 1.0 ko:K03086 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03021 1.0 - 1.0 - 1.0 - 1.0 Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 567696 0 0 267979 0 0 0 0 0 0 241213 0 0 234187 0 0 0 0 0 222396 0 258419 0 0 0 0 0 0 0 0 477547 376708 0 0 0 450308 0 0 403691 0 0 571375 0 0 0 0 0 0 437037 0 0 296339 0 0 0 0 0 280960 0 281353 0 0 0 0 0 0 0 0 536981 409687 0 0 0 329806 0 0 0 0 0 221411 0 0 0 0 0 0 161860 0 0 140866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144322 0 0 0 0 0 0 551369 0 0 553273 0 0 0 0 0 0 553987 0 0 440720 0 0 0 0 0 535530 0 430629 0 0 0 0 0 0 0 0 373751 569024 0 0 0 348144 0 0 0 0 0 52272 0 0 0 0 0 0 76644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54236 0 0 0 0 -AAMDIADKGK MGYG000003937_00998 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 2ET0Z@1|root,33KJ7@2|Bacteria,1VNW5@1239|Firmicutes,254DV@186801|Clostridia,3WQEJ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-ribbon_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 779665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 881781 0 0 0 0 418855 0 0 496171 0 840939 0 0 0 0 0 0 0 0 584261 0 607890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119928 0 0 0 0 222517 0 0 350126 0 92499 0 0 0 0 0 0 0 0 166014 0 286766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 940889 0 0 0 0 0 0 0 391394 0 621090 0 0 0 0 0 0 0 0 105414 0 283302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241556 0 0 0 0 49701 0 0 47281 0 244556 0 0 0 0 0 0 0 0 100171 0 165856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125437 0 0 0 0 107027 0 0 198584 0 272053 0 0 0 0 0 0 0 0 419491 0 -AAMDKIEK MGYG000002438_03132 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,2FN5D@200643|Bacteroidia,22WEY@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 L 1.0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage 1.0 recA 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 - 1.0 ko:K03553 1.0 ko03440,map03440 1.0 M00729 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03400 1.0 - 1.0 - 1.0 - 1.0 RecA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Homologous recombination 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1135403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMDSGVAR MGYG000000243_02147 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,2FM2T@200643|Bacteroidia,4AKYC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 maeB 1.0 - 1.0 1.1.1.38,1.1.1.40 1.0 ko:K00027,ko:K00029 1.0 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 1.0 M00169,M00172 1.0 R00214,R00216 1.0 RC00105 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,PTA_PTB,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 malate dehydrogenase (oxaloacetate-decarboxylating). | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. | The enzyme catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate, cf. EC 1.1.1.38 and EC 1.1.1.39. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. | (1) (S)-malate + NADP(+) = CO2 + NADPH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Metabolic pathways;Two-component system;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1981767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3077179 0 0 0 0 2878083 0 0 371347 0 0 0 0 0 0 0 0 0 1147970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 714545 0 0 0 0 513280 0 0 396818 0 0 0 0 0 0 0 0 0 811048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416498 0 0 0 0 0 0 0 0 0 1133772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437576 0 0 0 0 815667 -AAMDSGVARK MGYG000000243_02147 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,2FM2T@200643|Bacteroidia,4AKYC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 maeB 1.0 - 1.0 1.1.1.38,1.1.1.40 1.0 ko:K00027,ko:K00029 1.0 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 1.0 M00169,M00172 1.0 R00214,R00216 1.0 RC00105 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,PTA_PTB,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 malate dehydrogenase (oxaloacetate-decarboxylating). | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. | The enzyme catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate, cf. EC 1.1.1.38 and EC 1.1.1.39. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. | (1) (S)-malate + NADP(+) = CO2 + NADPH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Metabolic pathways;Two-component system;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 856202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMDTDDKNVR MGYG000002545_02040;MGYG000002223_00474;MGYG000004487_01385;MGYG000000039_01246;MGYG000002143_00092;MGYG000001300_01096;MGYG000002610_00641;MGYG000004791_00484;MGYG000000099_02658;MGYG000000739_01736;MGYG000004482_00415;MGYG000003819_01815;MGYG000003291_01172;MGYG000000022_00767;MGYG000004784_01270;MGYG000004475_00794;MGYG000001255_01028;MGYG000002105_01011;MGYG000002272_02459;MGYG000002926_00921;MGYG000000195_00123;MGYG000002040_01360;MGYG000002057_00134;MGYG000001616_01899;MGYG000004525_02384;MGYG000001225_01335 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.9615384615384616 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism;RNA degradation;Pyrimidine metabolism 1.0 none 1.0 1292686 1128772 1368832 1744484 742934 914269 1701413 1317868 1568291 1112037 1264148 1146126 1190173 1681528 1242419 978727 1115324 1591828 1458704 1462624 1226941 1041039 1564910 1164681 1342774 1286850 1160867 1461743 1173453 1134580 1182295 956879 1099974 1824278 1219383 1272766 1150922 1452439 2056415 1037269 1307558 3191041 1010043 1502234 3489895 1627373 2312505 974124 962059 2335574 1184052 2419837 2128667 1116094 2230380 1227062 2823767 2150230 1325400 963817 1452614 1196510 2416321 2332967 2432207 1235954 144495 1424302 1347128 1235624 1478480 2032678 1285444 2016671 2505020 1674230 774255 615339 604544 1143998 640233 863410 1060058 820338 954068 801988 895554 885268 596688 815085 1022915 665386 808603 707857 1044787 1010784 909881 792924 903496 840534 772215 1058275 824385 1031456 819189 1104943 676698 736279 714091 905647 946472 908604 1223374 822906 1286878 1081495 1749290 1052411 1181263 1376088 1721343 869273 1260625 1394062 896572 1297656 919859 1148812 1067530 1015090 1338971 1041642 1818775 1304116 677941 1459587 377731 1866117 1146604 1096926 1032726 1117647 964065 1419419 1748363 1141175 1477043 1383931 757786 900024 1212364 1730917 365759 194070 307568 219648 305721 233542 511563 465246 396627 299314 0 240766 450874 368987 295129 355245 222127 1064871 273939 318679 210012 286276 1201527 191706 345333 505024 348387 1096747 461822 181072 217873 265798 376591 364695 832987 470607 263480 394326 -AAMDTVTEHR MGYG000002517_01047 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways;Drug metabolism - other enzymes 1.0 none 1.0 0 0 0 0 0 0 0 0 61607 0 0 0 0 0 215244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 800769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 738054 0 0 0 0 0 712463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMDYAAIDNAPEEKER MGYG000001487_02232 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Beduini|s__Beduini massiliensis|m__MGYG000001487 1.0 COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 620555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3033758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMEDVLK MGYG000002515_00366;MGYG000002506_02188;MGYG000002323_03171 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria,3XN36@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) 1.0 luxS 1.0 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 1.0 4.4.1.21 1.0 ko:K07173 1.0 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 1.0 M00609 1.0 R01291 1.0 RC00069,RC01929 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 1.0 LuxS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 S-ribosylhomocysteine lyase. S-ribosylhomocysteinase. The 4,5-dihydroxypentan-2,3-dione formed spontaneously cyclizes and combines with borate to form an autoinducer (AI-2) in the bacterial quorum-sensing mechanism, which is used by many bacteria to control gene expression in response to cell density.-!-Formerly EC 3.2.1.148 and EC 3.3.1.3. S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3- dione + L-homocysteine. 1.0 1.0 1.0 1.0 Biofilm formation - Vibrio cholerae;Biofilm formation - Escherichia coli;Cysteine and methionine metabolism;Metabolic pathways;Quorum sensing;Biosynthesis of amino acids 1.0 none 1.0 815118 0 658522 707304 0 1850313 923233 951850 758074 1012713 0 0 0 0 806419 0 0 0 499068 654061 816547 1704929 0 2351087 664373 594097 0 0 760705 0 0 0 945887 1113652 870972 816536 554199 1063625 486844 0 343833 318781 0 1019294 286774 430516 250205 553410 0 0 0 0 231681 0 0 0 0 211351 186517 1292679 0 906240 322492 326341 0 0 245654 0 0 0 531956 388450 479658 404858 512283 587716 1225646 0 1741929 812631 0 2763015 1475341 1507839 1403431 1368246 0 0 0 0 1196284 0 0 0 594766 1439183 1538179 1789544 0 2336270 1626460 892249 0 0 1001524 0 0 0 617254 1604322 1442767 1171874 922956 1255519 1052650 0 1325157 821775 0 1434315 1147816 1383933 1261473 1228228 0 0 0 0 1043844 0 0 0 987920 1211008 1035029 1161729 0 1244112 132445 953953 0 0 854271 0 0 0 1369586 1292096 1193740 1422523 969869 1231753 0 0 0 0 0 0 154654 0 0 228813 0 0 0 0 200698 0 0 0 0 134412 0 0 0 74407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMEEADITPETSVSDTC(Carbamidomethyl)DKMK MGYG000000255_02549 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,21XVQ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Receptor family ligand binding region 1.0 braC 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters 1.0 none 1.0 352950 0 0 0 0 0 0 326480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 747525 0 0 0 0 0 0 912888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644232 0 0 0 0 0 0 0 0 0 0 463523 0 0 0 0 0 0 0 0 317250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 279220 0 -AAMEEANHASR MGYG000001494_01606 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Mesosutterella|s__Mesosutterella massiliensis|m__MGYG000001494 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,3VT2K@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581910 0 0 0 0 0 0 0 0 0 0 0 0 0 539219 0 0 0 0 0 0 0 0 0 0 821600 0 0 0 0 0 0 0 0 0 0 489134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMEEGVVVGGGTTYIR MGYG000000215_01245 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella stercorea|m__MGYG000000215 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMEEHASEAIR MGYG000000164_02794 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0191@1|root,COG0191@2|Bacteria,1TRS4@1239|Firmicutes,3VSU5@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 H 1.0 Fructose-bisphosphate aldolase class-II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1058966 0 0 652332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMEGMLAPTLK MGYG000000243_02364;MGYG000003681_01846;MGYG000000042_02977;MGYG000002478_00983;MGYG000000224_02076;MGYG000001313_00551;MGYG000001787_00060;MGYG000001346_01637 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,4AKHK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 890393 0 885424 957940 914249 776279 1154328 601374 745187 721207 725266 0 998528 607253 640883 857681 703745 442952 661660 815104 867764 580835 968205 940395 679272 798128 940719 938441 844609 864938 846515 0 1066897 0 681468 978655 770142 885291 922678 0 979402 1045184 1092889 759344 927979 1141430 484317 829923 905916 0 1598448 1339593 1048011 1508914 772350 802776 1005071 772597 984249 755479 1130114 730058 956817 1018222 1006917 902696 682914 821487 538374 0 815666 0 936619 849006 928686 931154 708914 0 580719 681066 1091284 1010959 1365106 480233 916642 281993 1076785 0 1048361 782534 914545 838090 804978 1517375 618040 685785 735136 668335 1247028 714613 650632 842139 596886 1243927 804030 730250 849856 0 615130 0 727772 1035771 783938 741431 231477 0 438215 134715 862894 265889 449614 387958 240952 343741 447277 0 485153 313345 523343 424380 929162 1073877 354917 1185320 467405 374350 1243696 449652 429584 251113 302293 439471 251168 857852 316838 0 358446 0 367619 476781 400423 256783 817964 0 534756 477971 1014503 632206 779987 851203 696325 388246 748316 0 1116460 545856 848040 1034475 674653 1558326 790479 831715 588064 596744 1366956 569921 812862 754537 251409 1339312 700344 978385 466498 0 442375 0 695635 720148 694516 542590 -AAMEHGLK MGYG000002156_01377;MGYG000004475_01165;MGYG000002926_00510;MGYG000002720_00255;MGYG000001733_00006;MGYG000002794_00566;MGYG000002882_01857;MGYG000004487_00995;MGYG000000089_01469;MGYG000003494_00371;MGYG000004769_00463;MGYG000004779_01663 domain d__Bacteria 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,2N77W@216572|Oscillospiraceae 0.6666666666666666 186801|Clostridia 0.9166666666666666 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1313872 0 981731 0 510854 1426308 1826714 1029285 0 1308196 972881 811578 0 0 0 0 1732244 1557639 0 0 0 1384854 1432843 1128301 0 1448747 0 1915307 0 794070 0 1288744 1400437 0 1144438 1397666 1777636 1004284 1197549 0 1324421 0 1444679 1271364 1357701 1878494 0 1175697 1636565 1100788 0 0 0 0 1026617 0 0 0 0 1080714 0 1103873 0 1476008 0 0 0 939401 0 1464163 916951 0 1341393 1848654 1135425 685357 321119 0 1530485 0 484775 966669 515951 1169485 0 661925 1102575 660128 0 0 0 0 851905 0 0 0 0 1691169 0 676925 0 822527 0 0 0 360804 0 858010 936874 0 1308019 1392701 1071933 1157352 1479759 0 1116420 0 1113885 1259604 1658840 1720023 0 1100354 1076818 1755135 0 0 0 0 1575803 938685 0 0 0 1230700 146593 1391590 0 1945417 0 751517 0 1105358 0 1637465 794298 0 1436638 560004 1356261 1354762 0 0 387089 0 0 0 473768 326126 0 498319 426721 0 0 0 0 0 328040 0 0 0 0 480680 0 847371 0 612483 0 0 0 338322 0 476718 571117 0 1101797 0 1052950 796701 -AAMESGVAR MGYG000002293_01153;MGYG000002478_00270;MGYG000002455_00092;MGYG000003922_01120;MGYG000001346_00985;MGYG000003697_02058 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,2FM2T@200643|Bacteroidia,4AKYC@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 maeB 1.0 - 1.0 1.1.1.38,1.1.1.40 1.0 ko:K00027,ko:K00029 1.0 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 1.0 M00169,M00172 1.0 R00214,R00216 1.0 RC00105 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,PTA_PTB,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 malate dehydrogenase (oxaloacetate-decarboxylating). | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. | The enzyme catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate, cf. EC 1.1.1.38 and EC 1.1.1.39. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. | (1) (S)-malate + NADP(+) = CO2 + NADPH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Metabolic pathways;Two-component system;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 3371764 0 0 0 0 2810567 0 0 0 0 2617444 0 0 0 0 1870695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4062542 0 0 0 0 2236616 0 0 0 0 3811578 0 0 0 0 2751801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1815268 0 0 0 0 3124059 0 0 0 0 2575766 0 0 0 0 1803466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2065891 0 0 0 0 2877183 0 0 0 0 3742776 0 0 0 0 4934116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4232225 0 0 0 0 3990118 0 0 0 0 3306761 0 0 0 0 3354733 0 0 0 0 0 0 0 0 0 0 -AAMEYGLK MGYG000003891_01855;MGYG000004201_00250;MGYG000001658_00361 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,268PI@186813|unclassified Clostridiales 0.6666666666666666 186801|Clostridia 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 741900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMFEER MGYG000001378_04455;MGYG000001313_00778;MGYG000004876_01712 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,4AMRT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 GK 1.0 Psort location Cytoplasmic, score 9.26 1.0 glk 1.0 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Neomycin, kanamycin and gentamicin biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMGNFAAFSAIPGVEVR MGYG000002274_00295;MGYG000002641_00490;MGYG000001300_00512 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3032229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 33881705 0 0 0 0 122582061 0 0 0 0 23595456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15354422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13593967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMGNFASFEAIPGIEVR MGYG000004271_00710;MGYG000000271_01845 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMIEYAQVIAK MGYG000000045_00137 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG0469@1|root,COG0469@2|Bacteria,2NNKX@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 G 1.0 Belongs to the pyruvate kinase family 1.0 pyk 1.0 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 1.0 2.7.1.40,2.7.7.4 1.0 ko:K00873,ko:K00958 1.0 ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050,M00176,M00596 1.0 R00200,R00430,R00529,R01138,R01858,R02320,R04929 1.0 RC00002,RC00015,RC02809,RC02889 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iECO103_1326.ECO103_1819,iPC815.YPO2393 1.0 ATP-sulfurylase,PEP-utilizers,PK,PK_C,PUA_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate kinase. | sulfate adenylyltransferase. phosphoenol transphosphorylase. | sulfurylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. | The human phosphoadenosine-phosphosulfate synthase (PAPS) system is a bifunctional enzyme: ATP sulfurylase, which catalyzes the formation of adenosine 5'-phosphosulfate (APS) from ATP and inorganic sulfate and the second step is catalyzed by the APS kinase portion of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase, which involves the formation of PAPS from enzyme bound APS and ATP.-!-This is in contrast to what is found in bacteria, yeasts, fungi and plants, where the formation of PAPS is carried out by two individual polypeptides, EC 2.7.7.4 and EC 2.7.1.25. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. | ATP + H(+) + sulfate = adenosine 5'-phosphosulfate + diphosphate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Sulfur metabolism;Microbial metabolism in diverse environments;Carbon metabolism;Type II diabetes mellitus;Monobactam biosynthesis;Central carbon metabolism in cancer;Metabolic pathways;Viral carcinogenesis;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Glucagon signaling pathway;Human papillomavirus infection;Purine metabolism;Selenocompound metabolism;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 1179798 0 0 0 0 0 765818 0 0 0 0 413874 0 0 0 0 703105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575102 0 0 0 0 0 1035586 0 0 0 0 480851 0 0 0 0 669600 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608948 0 0 0 0 0 473086 0 0 0 0 563464 0 0 0 0 593604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723356 0 0 0 0 0 981938 0 0 0 0 0 0 0 0 0 518038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307335 0 0 0 0 0 0 0 0 0 293464 0 0 0 0 0 0 0 0 0 0 -AAMIQNHQIGLSGGTEK MGYG000002438_03064 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22XE6@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603066 0 0 788440 0 0 0 0 0 0 362653 0 0 0 0 0 0 0 475764 1141892 0 0 0 0 0 0 0 0 774819 0 796190 0 0 0 0 0 0 0 295611 0 0 200261 0 0 0 0 0 0 371731 0 0 0 0 0 0 0 0 706667 0 0 0 0 0 0 0 0 292457 0 572389 0 0 0 0 0 0 0 1609014 0 0 1778866 0 0 0 0 0 0 1639348 0 0 0 0 0 0 0 1060107 4524556 0 0 0 0 0 0 0 0 4316459 0 2536792 0 0 0 0 0 0 -AAMIQSGQADIVVAGGTENMSSAPYLLR MGYG000002485_00796 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0183@1|root,COG0183@2|Bacteria,378R0@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 I 1.0 Belongs to the thiolase family 1.0 - 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588218 0 0 0 727773 0 0 711147 0 0 1132732 0 0 0 0 0 875284 0 662240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 205118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362521 0 0 0 0 0 0 339756 0 0 443822 0 0 0 0 0 436091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMKEASEGELK MGYG000004468_00660;MGYG000000044_01948;MGYG000001749_01249;MGYG000001783_01519;MGYG000001546_00360;MGYG000001489_03093;MGYG000004006_01717;MGYG000002007_00386;MGYG000004756_01346;MGYG000003202_00946;MGYG000003681_00790;MGYG000001345_01069;MGYG000002438_00285;MGYG000003514_00715;MGYG000000003_00712;MGYG000000196_00479;MGYG000001562_00044;MGYG000004464_00783;MGYG000001661_02632;MGYG000001313_02393;MGYG000002549_00455;MGYG000001415_02219;MGYG000001337_01464;MGYG000002737_00455;MGYG000004536_01441;MGYG000001789_00244;MGYG000000273_02725;MGYG000000053_01377;MGYG000002281_04045;MGYG000000478_01407 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.43333333333333335 976|Bacteroidetes 0.9 G 0.5333333333333333 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.9666666666666667 gap 0.9666666666666667 - 0.9333333333333333 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 322449 537570 1080607 297783 1519300 927303 624668 1161476 861588 790027 3488434 1510899 0 0 0 1272572 557044 240458 1082897 563379 531054 946263 530625 506280 950606 753698 208176 427371 0 0 1708482 1656652 691843 684424 694347 0 565931 1000528 125515 235438 297609 213062 366965 154554 194281 321087 0 318955 902624 204288 0 0 0 253936 353897 143704 0 154362 172705 220167 0 0 314545 0 152531 183358 0 0 132688 547456 98642 76652 268025 0 209045 144046 862527 1239291 2293224 506545 1822362 1778995 1058632 1362745 1617581 1356393 3050843 463303 0 0 0 1233805 535960 283421 896590 1073234 496069 679638 241260 852567 1377138 611548 360507 0 0 0 1507714 1101233 991019 1473181 677502 0 1124093 1445836 2325381 2125142 2812891 2015084 3049781 3379530 1651920 3117134 2476128 2969210 4714622 2778099 0 0 0 3696602 2679810 2256942 3229546 1979449 1738515 2455170 2068775 1475336 1741790 2346114 2478540 3384322 0 0 2439625 2328944 3020874 1883275 3150133 0 2569762 2672192 269433 489943 625706 267322 851965 786725 71272 461538 508306 838484 1771452 881079 0 0 0 765537 351183 312292 552808 89285 358178 648573 293713 328785 167319 218757 0 238710 0 0 670312 856365 608641 82906 287629 0 257166 700299 -AAMKPSATLFLAGAAPK MGYG000001365_00415 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A|s__Phascolarctobacterium_A succinatutens|m__MGYG000001365 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TSVA@1239|Firmicutes,4H24P@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 - 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1328705 0 1040018 1147386 0 0 0 0 0 0 966064 0 0 811988 0 1619686 0 0 0 944933 1300001 1016598 0 0 0 1357407 637944 0 1677511 1474845 1315648 0 916125 0 0 1486945 -AAMLAIM(Carbamidomethyl)NPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMLAIM(Oxidation)NPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 422017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 451772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMLAIMN(Asn->Met)PDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 112532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMLAIMN(Deamidated)PDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 786873 0 271956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360571 0 0 0 0 0 0 188790 0 0 0 313390 270909 0 0 153366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135949 0 0 0 0 0 240963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86329 0 0 0 0 217678 93865 0 178137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258693 0 0 0 0 0 0 210508 0 0 0 202690 192606 268534 0 227657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281421 0 0 0 0 0 0 217090 0 0 0 122944 397760 -AAMLAIMNPD(Cation_Ca[II])DKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMLAIMNPD(Cation_Na)DKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMLAIMNPDDK MGYG000004719_02002;MGYG000001637_02230;MGYG000000271_02101;MGYG000001315_01867;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8333333333333334 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1043448 0 0 1323354 0 0 1149379 686006 812313 0 865846 1122935 0 441727 777863 0 0 0 557204 705243 874043 0 0 0 978531 787213 833769 0 837445 987497 0 0 0 0 0 939778 810094 0 143462 0 0 0 0 0 0 525672 0 0 0 0 0 0 0 0 0 0 0 434305 0 0 0 0 0 381893 285302 0 0 311888 0 0 0 0 0 480525 0 0 156804 0 0 0 0 0 371249 0 0 0 0 0 0 0 0 0 0 0 0 253149 506496 0 0 0 432710 612886 0 0 299635 578328 0 0 0 0 0 498933 398252 0 218385 0 0 346114 0 0 144279 0 124318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 568361 0 0 0 157644 0 0 0 0 0 222940 271403 0 335110 0 0 482634 0 0 605980 406372 419931 0 207822 862246 0 497307 341861 0 0 0 438436 474292 462492 0 0 0 621077 217774 353092 0 248870 670995 0 0 0 0 0 511649 343354 0 -AAMLAIMNPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 7231453 5265491 5417975 9596422 4907201 5082350 8373336 9243878 8390525 8851104 13210620 12026360 5213789 4977992 6985886 3684463 4893619 1478101 5722996 6723191 8283504 3998123 2021564 2921461 8238967 6470691 8016014 2458994 6394728 13549135 2186050 3166317 3721703 8670158 5596571 7678083 6874062 3637487 2275722 3607046 2151054 2874467 2667343 2469925 3036651 3075375 1587431 1960815 1877863 1559255 3226139 1791503 2191121 1443264 1447201 955685 2155413 3216558 1769971 1234748 906568 3578010 2684323 2434232 2584142 1020600 2806628 2124340 4581322 3611886 2015420 2665614 3261237 2483355 2042955 2532387 3898880 1598961 580759 1522434 735364 754304 2648302 2645715 2076660 1212280 1880238 4016467 3611461 2737029 3360892 2939942 2341381 464932 3128578 3114113 3661739 1095198 293159 675879 3771324 2764208 3669074 663181 2775917 4007166 852178 1571020 1956400 3031000 1621311 2614468 3375420 1082229 517926 420179 914251 282819 395420 314020 353490 440174 482181 251739 477490 1038330 610642 412667 499375 688295 312011 166433 299831 380714 304454 471742 191120 70674 360136 220429 366816 0 160280 258401 526968 364049 912595 190082 443034 273182 275631 625528 2477164 583259 3359028 867915 0 1848565 3437159 1491808 2625019 2137971 1629276 5947413 1415644 3534244 2007963 1271164 3269359 736122 2357883 1898657 2086381 2691383 1121984 1953331 2762191 2862327 1908722 1138005 893380 3096000 923576 0 4131653 8045834 10141129 2867642 12444006 9383444 -AAMLIILK MGYG000001370_03535 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fluxus|m__MGYG000001370 1.0 COG3516@1|root,COG3516@2|Bacteria,4NMKM@976|Bacteroidetes,2FTM9@200643|Bacteroidia,4AQBV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 T6SS_VipA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1551502 0 0 0 0 0 0 -AAMLLR MGYG000001346_01121;MGYG000002478_02896;MGYG000001599_00424;MGYG000000198_02428;MGYG000004797_02907;MGYG000000212_00238;MGYG000000179_00721 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.5714285714285714 976|Bacteroidetes 0.5714285714285714 S 0.5714285714285714 Psort location Cytoplasmic, score 8.96 0.5714285714285714 - 0.5714285714285714 - 1.0 - 0.5714285714285714 - 0.5714285714285714 - 0.5714285714285714 - 0.5714285714285714 - 0.5714285714285714 - 0.5714285714285714 - 0.5714285714285714 - 1.0 - 1.0 - 1.0 GGGtGRT 0.5714285714285714 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.5714285714285714 0.5714285714285714 0.5714285714285714 0.5714285714285714 0.5714285714285714 none 1.0 222435 0 0 0 0 0 0 0 0 0 0 0 0 0 201347 0 0 0 0 0 314033 0 0 0 0 222564 185633 0 0 0 0 0 95563 0 0 0 272931 0 86912 0 0 0 0 0 0 0 0 0 106143 0 67811 106136 87794 0 0 0 0 0 0 0 0 0 0 90513 0 0 0 0 0 0 0 0 0 0 74131 83732 1375267 0 1638145 0 0 0 0 0 0 0 1712137 0 1922258 1851867 1693114 0 0 0 0 0 1386516 0 0 0 0 1235494 1111551 0 0 0 1367743 0 847206 0 0 0 1410665 1599990 230733 0 230040 0 0 0 0 0 0 0 97069 0 127967 106631 105871 0 0 0 0 0 117063 0 0 0 0 139241 123868 0 0 0 161517 0 164170 0 0 0 164352 109979 97387 0 80358 0 0 0 0 0 0 0 297955 0 408617 71901 0 0 0 0 0 0 107698 0 0 0 0 1062384 102487 0 0 0 0 0 117719 0 0 0 717669 877041 -AAMLNYQTQTAQAQEAYDNAMK MGYG000000196_05075 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 2AFRI@1|root,315TH@2|Bacteria,4PK03@976|Bacteroidetes,2FTKM@200643|Bacteroidia,4ARI1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 453152 659326 0 917235 0 0 0 341714 412602 0 321114 0 0 0 580474 280753 1679577 0 898969 230423 171441 385102 0 491405 0 451269 0 0 0 0 0 0 838401 0 0 0 503093 510883 796656 1314755 0 353228 0 427408 2118989 0 0 286956 471774 1502899 0 0 831483 0 647657 0 0 395579 0 1318589 0 2036905 0 516614 299593 0 0 0 0 791040 1063228 113796 0 0 0 2195369 0 0 0 0 0 0 354759 160104 0 0 0 0 0 0 0 0 0 0 0 0 0 268607 0 575686 0 0 0 0 0 0 0 575418 487009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133078 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2772887 2450634 1882571 2924454 0 1612576 4569251 3581162 3174835 2774258 2189882 3186523 1585098 0 2682193 2260825 3331858 0 1901521 3192837 3716522 2359599 0 1909033 0 2751508 3015145 0 2937801 0 0 2100447 940412 4596070 0 3004083 1845810 1754992 -AAMLSIMNPDDKAGLEAALR MGYG000000997_00555 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900548205|m__MGYG000000997 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMLT(Thr->Ala)IMNPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 807932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMLTIM(Carbamidomethyl)NPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 330771 226795 194973 0 0 0 0 0 0 0 0 0 0 0 0 0 141079 0 0 0 0 212471 0 87344 0 0 0 0 0 0 82073 0 0 0 0 0 67245 0 167066 44687 120216 0 0 83361 0 0 146282 0 0 0 0 0 0 0 196887 0 0 0 0 0 0 80209 0 175941 0 0 0 0 0 0 0 0 0 76133 0 77913 368693 563713 159271 0 0 105139 0 0 309192 0 0 0 0 0 0 0 191230 0 0 0 0 621761 0 97397 0 464927 0 0 0 0 0 0 194557 0 0 0 339364 0 413125 0 63806 0 0 0 0 0 171047 0 0 0 0 0 0 0 109483 0 0 0 0 0 0 0 0 271300 0 0 0 0 0 0 0 0 0 216445 572417 0 522791 394779 673397 0 0 796438 0 0 990118 0 0 0 0 0 0 0 606890 0 0 0 0 536558 0 595325 0 645940 0 0 0 0 865094 0 783861 0 0 581983 327208 786293 -AAMLTIM(Oxidation)NPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 877578 736033 607539 919335 739701 387883 345639 1105228 596962 1072969 509859 825575 702895 639958 1405635 1450995 1780806 0 1026935 1116946 880455 1927698 0 234973 1143651 844035 738950 0 335988 206121 0 545294 409543 251142 738643 650501 836236 310095 520050 581472 266606 302927 474720 361738 803020 822594 1319071 682777 306256 648705 262949 465239 392033 391046 553367 0 240182 690989 417995 0 0 718722 711224 561919 714089 0 1003107 312009 0 247484 279155 576885 528601 760431 593305 303382 1692164 3474227 266565 2487850 1250621 901113 492538 1546131 536269 1932623 564654 1279622 1131326 1225060 1779234 1321320 1250509 0 1888123 1584955 1235728 1919269 0 739405 1925942 1876777 1715828 0 1059999 1161131 0 1383783 831355 1911983 1929197 594237 1495433 407185 1934831 690431 426440 1577080 1072659 851046 1085442 0 1970087 1376665 731508 1290902 979933 2549260 2569273 1304522 1401464 0 1447124 2423726 2401442 352071 0 220443 2330076 1921078 2018345 0 571918 1960115 0 804859 536793 1407701 1999797 1438617 2315805 240897 2147942 2683274 3978243 503712 2050676 2984572 2440260 1896726 2770541 4596052 4003974 2369610 1656265 5352940 4257500 1988197 3169928 0 2956326 1697060 2057157 2020073 0 3110735 3709450 2370618 3665565 0 1071027 1576094 0 1066845 3303097 2148854 2687520 3139032 3980915 2524199 -AAMLTIMNPD(Cation_Ca[II])DKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 0 96572 0 198278 245715 77562 76595 0 191708 196444 0 0 0 0 161865 90548 108477 0 244635 0 0 330315 0 85161 58114 0 111343 0 0 0 0 0 150226 215350 0 116440 0 120683 0 126998 95462 238603 185435 0 326841 0 63945 306124 0 0 0 0 223130 64472 241731 0 133470 0 0 0 0 103429 216436 0 170574 0 0 0 107731 0 134778 280397 0 248802 0 67519 0 308689 0 581918 0 120661 155132 0 0 542088 0 0 0 0 493458 375140 334657 0 327066 0 0 529435 0 0 449950 0 569991 0 0 0 0 0 68504 477747 0 239646 0 0 0 57645 74481 408901 506932 187580 531623 0 582204 110723 0 0 0 0 672183 288025 491574 0 319595 0 0 93290 0 0 422879 0 789325 0 0 0 0 0 57581 430130 0 296833 0 0 0 719015 1407738 220629 609088 771883 711522 0 644917 1017222 0 0 0 0 1211119 617858 930211 0 760616 0 0 646368 0 400596 802795 0 694519 0 0 0 870203 0 665488 993223 0 643681 0 1136444 -AAMLTIMNPD(Cation_Fe[II])DKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 142132 0 90604 0 0 138936 0 0 88298 323346 0 0 0 0 88701 0 149418 0 136291 0 0 282705 0 57623 0 145438 0 0 0 0 0 0 0 131638 0 0 81093 109035 62742 0 0 0 0 71538 246272 0 56358 198277 0 0 0 0 125745 0 166707 0 89397 0 0 0 0 73183 0 104297 0 0 0 0 0 0 42079 310019 0 0 54519 0 201299 0 0 0 0 92177 75662 0 53134 89509 0 0 0 0 188180 0 102359 0 282538 0 0 250112 0 0 0 134579 0 0 0 0 0 0 99500 166126 0 0 96153 0 531412 0 0 0 0 330467 171421 0 480024 184631 0 0 0 0 511630 0 122523 0 205507 0 0 0 0 0 0 390150 0 0 0 0 0 0 0 196613 0 0 503600 0 520201 0 842921 0 0 530477 507517 0 587162 874993 0 0 0 0 687129 0 806457 0 543846 0 0 0 0 361495 0 383412 0 0 0 0 0 0 569867 809641 0 0 516321 972076 -AAMLTIMNPD(Cation_Mg[II])DKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 195503 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334521 0 0 0 0 0 0 0 0 0 227267 214901 0 505700 0 0 0 0 0 0 0 0 0 374500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 607197 0 0 0 0 0 0 0 0 0 303276 323163 0 833354 0 0 0 0 0 0 0 0 0 136299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 790493 0 0 0 0 0 0 0 0 0 920966 827743 0 1284024 0 0 0 0 0 0 0 0 0 778410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 793256 0 0 0 0 0 0 0 0 0 1098526 709205 0 -AAMLTIMNPD(Cation_Na)DKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 0 0 276580 472680 0 187837 0 654003 0 0 0 0 0 0 396992 236595 0 0 0 0 436398 160517 0 375838 0 443285 529465 0 0 373108 0 0 0 236673 347179 475131 553598 472370 91444 0 262510 235690 0 0 0 285428 0 0 0 0 0 0 223313 0 0 0 0 0 433493 306021 0 98344 0 649482 375028 0 0 0 0 0 0 577673 509453 174181 474449 0 1053686 0 252155 1144194 0 420009 0 817664 0 0 0 0 0 0 910155 533144 0 0 0 0 807284 872797 0 398260 0 661999 908434 0 0 515539 0 0 417696 1113919 1194700 331032 824295 319016 1242066 0 238483 936109 0 530495 0 1270530 0 0 0 0 0 0 1392687 609204 0 0 0 0 911457 118239 0 0 0 1133556 1139572 0 0 774502 0 0 388668 723095 1033435 1028612 1424608 248736 0 0 0 290710 0 1642603 0 0 0 0 0 0 0 0 2236418 1537570 0 0 0 0 1410287 842714 0 847561 0 1990513 442848 0 0 1288724 0 0 1020682 1707640 323325 0 1114034 1670205 -AAMLTIMNPDD(Cation_Ca[II])KAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64030 0 0 0 0 0 0 0 0 0 0 0 0 68966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254050 0 0 0 0 0 0 0 0 0 0 0 0 326041 0 0 0 0 0 0 0 0 0 0 277111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 760017 0 0 0 0 0 0 592039 0 0 501539 669440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 636061 0 -AAMLTIMNPDD(Cation_Fe[II])KAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516623 631738 0 0 0 0 0 0 0 0 599755 0 0 0 0 419915 0 0 -AAMLTIMNPDDK MGYG000000077_02468;MGYG000002278_01894;MGYG000004740_00274;MGYG000000087_01268;MGYG000001809_02343;MGYG000000255_01557;MGYG000002517_00543;MGYG000000154_01281;MGYG000000262_02235 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae 0.3333333333333333 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.3333333333333333 etfB 1.0 - 0.6666666666666666 - 0.6666666666666666 ko:K03521 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.6666666666666666 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 1.0 none 1.0 686880 473968 0 673746 489673 350410 0 863139 0 978434 0 0 428272 721290 1453466 319415 390606 0 918711 861562 632619 537274 0 0 1378329 934567 637612 0 333548 0 0 0 277890 0 485769 354055 327571 0 2052662 1397510 1187980 2187137 1130098 1818562 2894083 2060681 1405104 1717317 871457 1611445 1150073 1648675 1593120 1288629 1908579 0 1837798 2721883 2049999 914282 0 1741462 1826173 1747972 2261146 0 2763125 1746041 1243947 1073710 1279226 2502682 1706948 2185588 1571227 1142403 2082086 1045606 657085 2082585 0 733370 1104658 1506978 1034845 1569653 836753 1197705 1181998 1542119 2073662 1124697 1358027 0 2227089 1920210 1652283 2266556 0 702716 1921553 2703917 1976211 0 479912 1640515 396727 1157020 979634 2048529 1895188 1072520 1666974 743558 3404571 1638014 965225 3525982 2284733 1291108 3246873 2873011 3494654 2013984 1501309 1621035 1502587 4929744 3145313 2525657 3315310 0 2674700 3651645 2755888 983629 0 894207 3324031 2733471 3353669 0 1905518 3181850 1168291 1347793 1412017 1513360 2941441 2599708 3527811 925531 3984512 3407159 4156767 513136 1597929 4705483 4584664 4340805 4038250 5154737 2874109 3738028 1180495 5480168 5853747 4618821 4905735 0 5479264 3606143 5280266 3039121 0 3609510 5944982 3785795 5250385 0 1454975 3350171 2952149 1043685 3610638 5634735 3239788 5037103 4338703 3280343 -AAMLTIMNPDDK(Propionamide) MGYG000000077_02468;MGYG000002278_01894;MGYG000004740_00274;MGYG000000087_01268;MGYG000001809_02343;MGYG000000255_01557;MGYG000002517_00543;MGYG000000154_01281;MGYG000000262_02235 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae 0.3333333333333333 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.3333333333333333 etfB 1.0 - 0.6666666666666666 - 0.6666666666666666 ko:K03521 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.6666666666666666 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1546297 0 1595075 0 0 0 0 2253219 0 0 0 0 0 0 0 0 0 0 0 2257335 0 0 0 0 0 0 2118304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMLTIMNPDDKA MGYG000000077_02468;MGYG000002278_01894;MGYG000004740_00274;MGYG000000255_01557;MGYG000002517_00543;MGYG000000154_01281;MGYG000000262_02235 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae 0.42857142857142855 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.42857142857142855 etfB 1.0 - 0.5714285714285714 - 0.5714285714285714 ko:K03521 0.5714285714285714 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.5714285714285714 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.5714285714285714 0.5714285714285714 0.5714285714285714 0.5714285714285714 1.0 none 1.0 0 0 0 333296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395782 330258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 387562 0 158823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2479908 0 866811 2056301 0 893258 848147 0 1397873 0 0 1433307 1406192 2211640 0 1183354 955100 0 2259416 2681518 1689139 1583791 0 530884 2733193 2130433 0 0 0 1469872 0 0 944039 0 1636331 1119321 2109533 444237 2328797 0 0 2556249 1124040 627102 1874387 0 2938104 1013418 0 980320 454931 1626567 0 1000040 2405295 0 1165880 2574267 1508851 0 0 0 1435339 1450666 0 0 0 1287442 0 0 719511 0 1582178 2189396 1745914 463395 405239 0 0 0 406457 0 0 0 321492 0 0 845060 0 0 0 313992 448040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMLTIMNPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.75 0.75 0.75 0.75 1.0 none 1.0 9308575 9170787 8318703 11893453 9947265 7789382 5062534 16385450 8161981 16954929 6778462 11107000 8960861 7413667 11243687 6470418 7639788 1761730 14406241 11431027 11593901 10866563 2956351 4108547 11292737 8685687 10473085 3639458 4721443 8840247 3650239 6304923 4331664 8311170 11293905 7827666 8461722 4968916 9552178 7536478 4075044 13067461 7559503 6897509 14601512 14488261 6069136 10796797 6656181 9033219 6848377 8354740 11348079 5521258 10250376 770510 9620186 15270824 8312924 4907571 0 9613636 10004160 13207561 11179687 384211 15559944 6810047 8127255 6752867 4162696 11269323 9187258 13191439 8798947 3928338 17991533 15935718 3108642 18093442 1071946 8778714 5677344 14542195 5120683 15747104 5385189 13288614 10285077 11601354 16519644 11499343 10508130 65104 21110921 16912638 11164150 20389875 633352 4585202 17990620 15618987 19246030 560237 2683695 11313729 2221672 11116201 8478769 19321232 21144968 5970714 13429626 3889229 28658678 4978339 5062213 21122762 10089963 9253731 11638997 26517507 26260112 9761725 7388188 10235363 8998778 26952807 24455464 12436086 13154661 0 14343646 18913476 18562304 3533624 0 1833595 26606682 23541426 28403939 0 3600132 18294880 3305862 7609344 5443166 15811475 27393708 18476664 29774831 2823441 31402788 30381263 51653745 4832726 18171974 35789090 36015801 23368484 30040511 49078131 40040169 32436970 16292554 57647134 51595920 28316611 47306483 0 38034178 21463349 34992893 29670053 0 32597726 46183232 44783131 43305927 0 10703825 27694132 38756705 16054446 48434612 42199599 24120041 49217675 37988885 43940483 -AAMPEAGPVILEPIHTLK MGYG000002274_01087;MGYG000001255_02150;MGYG000003899_02100;MGYG000002641_01949;MGYG000002040_00027;MGYG000004679_00212;MGYG000002272_00718;MGYG000002545_01805;MGYG000001300_02656;MGYG000003291_01552 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 translation elongation 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 576492 700618 802991 906996 272577 487998 404807 527673 688330 0 755083 570459 530608 477745 475970 490343 0 1907987 909355 656432 0 467465 2114624 513302 583206 586104 596335 2209011 0 583326 703942 541288 602272 657451 0 500296 557070 699497 1256111 0 882924 1940542 877008 1318926 1603260 905786 1281621 0 936700 977432 1020599 1671482 1507534 814405 0 2879959 2150613 2077389 0 965145 2735059 1191105 1838416 1743784 1490910 2695285 0 1018039 931072 792218 905762 1169169 0 1331200 1177056 992630 510188 591972 803365 578770 603791 435602 555438 509844 633070 0 668778 708335 556757 466590 440608 460324 0 2404015 738346 301390 0 405790 2374861 571535 542578 647596 472995 2655901 0 623535 489509 577083 431536 491171 0 447321 526546 614175 911381 747669 922481 874523 896668 908838 904982 551711 884810 0 884202 994758 897281 926246 772002 1032568 0 1651580 1146563 985817 0 833764 1728192 716533 910546 737071 675157 1561053 0 862517 862924 188793 987450 725919 0 677828 889403 861211 0 270312 306618 208577 98331 163643 180284 218224 139028 0 218601 182524 188862 100131 123450 184272 0 2762751 90979 0 0 0 3147067 82855 185945 201263 124208 3781739 0 174035 215616 264980 317394 90499 0 323502 101930 292085 -AAMQSDSGLPDVC(Carbamidomethyl)QMYDVGTK MGYG000000031_00361;MGYG000000142_00481;MGYG000000216_00704 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,4H2K7@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 929494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378344 0 0 0 0 0 0 0 0 0 0 0 0 712150 0 0 0 0 0 0 0 0 990377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 814569 0 0 0 1251727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMQTQASSAVDA(Ala->Thr)QAEAIK MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 866674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMQTQASSAVDAQA(Ala->Thr)EAIK MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 917421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMQTQASSAVDAQAEA(Ala->Thr)IK MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 862725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429511 0 714510 0 0 0 0 0 870654 0 0 0 0 0 0 0 0 -AAMSEATAPPMK MGYG000004735_00332 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase acetyl-CoA synthase delta subunit 1.0 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Methane metabolism;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMSGMLSPELK MGYG000002506_02810;MGYG000002535_00129;MGYG000002494_01785;MGYG000002534_00556 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,3WXXB@544|Citrobacter 0.75 1236|Gammaproteobacteria 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 546587 1057474 0 0 0 0 0 0 0 0 0 0 1113903 0 0 0 0 885254 0 1020231 0 0 0 0 0 0 0 0 0 0 0 0 0 631797 1050385 2126411 0 0 980756 3303064 3095529 0 1194563 0 0 0 0 1563152 0 0 3947199 0 0 0 2271057 4691654 0 1297258 0 1550360 0 0 0 0 0 0 705955 0 0 533986 1242555 0 663639 508083 475468 341518 766681 1173845 498720 0 605023 0 0 0 0 638627 0 0 720766 0 0 0 873358 898775 0 950902 0 369957 0 0 0 0 0 0 594459 0 0 535441 560607 549177 578206 0 0 601747 235083 613109 618204 0 442788 0 0 0 0 534988 0 0 728822 0 0 0 674734 541445 0 454866 0 337706 0 0 0 0 0 0 255409 0 0 704521 498483 322977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMSNELAAGYTLK MGYG000001658_01423 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01|s__SFFH01 sp900548125|m__MGYG000001658 1.0 COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1UJBN@1239|Firmicutes,24QYH@186801|Clostridia,26C5N@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,FAD_binding_2,FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 791555 0 0 0 0 1465893 0 0 0 0 1481763 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 606429 0 0 0 0 368457 0 0 0 0 0 0 0 0 0 0 -AAMTDATNEK MGYG000000028_00550;MGYG000002528_02184 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,27PJB@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein L35 1.0 rpmI 1.0 - 1.0 - 1.0 ko:K02916 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L35p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 140878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336758 0 612022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 722548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1962239 0 455494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMTVEK MGYG000000179_01986 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 2DKY9@1|root,30VCI@2|Bacteria,1V5YE@1239|Firmicutes,24HJZ@186801|Clostridia,21XSJ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 zinc-ribbon domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zinc_ribbon_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 478825 0 0 0 0 0 0 0 0 0 0 273610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 594713 0 0 0 0 0 0 0 0 0 0 785081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603093 0 0 0 0 0 0 0 0 0 0 1293631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683588 0 0 0 0 0 0 0 0 0 0 766805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1918255 0 0 0 0 0 0 0 0 0 0 1301541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMTVSISDMTEPPEKPQMIK MGYG000002517_00198 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 528473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 624778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMVEAMK MGYG000000233_02257;MGYG000000255_02594 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0544@1|root,COG2247@1|root,COG5263@1|root,COG0544@2|Bacteria,COG2247@2|Bacteria,COG5263@2|Bacteria,1UYJ9@1239|Firmicutes,248QE@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 S-layer domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Big_2,Big_3_5,CW_binding_1,Cadherin-like,Flg_new,LRR_5,SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 621074 0 0 0 0 0 0 424532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724542 0 0 0 0 0 0 436976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAMVPVVEPSDSAEAK MGYG000000179_00497;MGYG000000198_04624 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,26A1D@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates 1.0 iorA 1.0 - 1.0 1.2.7.8 1.0 ko:K00179 1.0 - 1.0 - 1.0 - 1.0 - 1.0 br01601,ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 indolepyruvate ferredoxin oxidoreductase. IOR. Preferentially utilizes the transaminated forms of aromatic amino acids and can use phenylpyruvate and 4-hydroxyphenylpyruvate as substrates.-!-This enzyme, which is found in archaea, is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = (indol-3- yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 1219862 0 0 0 0 0 0 0 0 431464 0 0 0 333308 1001652 0 0 0 0 1032066 0 0 0 0 371886 750098 455652 0 635539 0 0 0 0 0 0 748831 0 0 338483 0 0 152260 0 0 0 0 0 389312 0 0 0 0 296013 0 0 0 0 0 0 0 0 0 0 0 428685 0 150968 0 0 0 0 0 0 294928 355645 0 779154 0 0 462505 0 0 0 0 0 411050 0 0 0 815570 758330 0 490061 0 0 698231 0 0 0 0 0 638236 875131 0 919007 0 0 0 0 0 0 524092 518922 0 0 0 0 414865 0 0 0 0 0 463104 0 0 0 362640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424960 0 0 1141795 0 0 943727 0 0 0 0 0 1171798 0 0 0 1536212 1106028 0 1205713 0 0 1166961 0 0 0 0 843479 1063784 1250186 0 1255275 0 0 0 0 0 0 1198684 1091706 0 -AAMVPVVEPSDSAEAKDFMK MGYG000000179_00497 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,26A1D@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates 1.0 iorA 1.0 - 1.0 1.2.7.8 1.0 ko:K00179 1.0 - 1.0 - 1.0 - 1.0 - 1.0 br01601,ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 indolepyruvate ferredoxin oxidoreductase. IOR. Preferentially utilizes the transaminated forms of aromatic amino acids and can use phenylpyruvate and 4-hydroxyphenylpyruvate as substrates.-!-This enzyme, which is found in archaea, is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = (indol-3- yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 375426 0 0 188818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239775 0 0 0 0 0 0 0 0 332881 248477 0 278523 0 0 235041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124054 0 0 0 0 0 216026 294525 0 0 0 0 0 0 0 0 177128 0 0 0 0 0 408581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365955 0 0 387764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 645705 0 0 752606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 482160 0 0 0 0 0 756706 755540 0 0 0 0 0 0 0 0 724806 763738 0 -AAMVTVAK MGYG000002494_04617 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,3XM4I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ 1.0 grpE 1.0 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 1.0 - 1.0 ko:K03687 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 GrpE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 796585 0 0 0 783747 618249 0 0 406324 0 0 0 0 0 0 355492 0 0 0 736840 1130508 0 1383486 230454 0 0 0 334219 434451 0 0 654552 0 0 0 0 492116 0 2367955 2644133 0 1857135 4009820 1919977 0 0 2802449 0 0 0 0 0 0 2418129 0 0 0 2578384 5424885 0 3697192 2252374 0 0 0 3007268 1831026 0 0 2907870 0 0 0 0 2515186 0 0 484296 0 0 374157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428480 0 0 0 0 0 0 0 0 0 0 0 0 0 845165 0 223348 639584 0 216108 656093 761817 0 0 530543 0 0 0 0 0 0 333684 0 0 0 347627 614073 0 281897 686843 0 0 0 175750 589925 0 0 374384 0 0 0 0 163826 0 0 0 0 0 752862 582211 0 0 0 0 0 0 0 0 0 0 0 0 0 429217 705226 0 659513 609385 0 0 0 451492 659714 0 0 0 0 0 0 0 459649 -AAN(Asn->Gly)GVIIITTK MGYG000001787_01504;MGYG000002478_00526;MGYG000000196_04885;MGYG000002438_03064;MGYG000002438_02925;MGYG000003697_01696;MGYG000003697_02942;MGYG000000243_02417;MGYG000000013_00116 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.3333333333333333 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 0.8888888888888888 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1013396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Asn->Gly)GVILITTK MGYG000002478_00836;MGYG000004748_01412;MGYG000003693_02459;MGYG000000013_01157;MGYG000002478_02338;MGYG000000196_04885;MGYG000002438_02656;MGYG000004703_01713;MGYG000002549_02801;MGYG000003697_01696;MGYG000003697_02942;MGYG000000105_01953;MGYG000001056_01040;MGYG000004899_00167;MGYG000003681_00932;MGYG000000224_02063;MGYG000001346_01792;MGYG000000174_02248;MGYG000001346_00980;MGYG000000029_03133;MGYG000000029_02281;MGYG000000003_01946;MGYG000003952_01841;MGYG000003693_01019;MGYG000001780_04788;MGYG000001378_04550;MGYG000002478_00526;MGYG000001661_01562;MGYG000000044_02806;MGYG000001661_00232;MGYG000001661_01167;MGYG000001306_00226;MGYG000002560_03505;MGYG000001345_04118;MGYG000003351_02635;MGYG000000196_04852;MGYG000001780_00424;MGYG000003367_00988;MGYG000000236_00670;MGYG000001489_01819;MGYG000000243_02417;MGYG000001783_00138;MGYG000000105_02058;MGYG000000781_02387;MGYG000003362_01220;MGYG000002455_01534;MGYG000002549_04362;MGYG000001789_02404;MGYG000003812_00487;MGYG000002293_00753;MGYG000001789_00624;MGYG000004797_01501;MGYG000002281_03192;MGYG000001489_03122;MGYG000000138_01670;MGYG000000044_02057;MGYG000001787_01504;MGYG000004876_00069;MGYG000002935_01014;MGYG000001345_03656;MGYG000000236_04565;MGYG000002478_02514;MGYG000002614_00404;MGYG000001056_00294;MGYG000004876_02160;MGYG000004006_01269;MGYG000003681_01449;MGYG000001666_00819;MGYG000004899_00413;MGYG000001378_02713;MGYG000001925_02044;MGYG000003493_02393;MGYG000000013_00116;MGYG000001503_01401;MGYG000004797_02606;MGYG000000138_01202;MGYG000001337_00935;MGYG000002438_02925;MGYG000001783_00512;MGYG000000224_00522;MGYG000003701_02338;MGYG000001599_02769;MGYG000000196_01084;MGYG000003681_02804;MGYG000002478_01281;MGYG000000105_01199;MGYG000001346_02872;MGYG000003363_00305;MGYG000001789_01698;MGYG000004899_00346;MGYG000004830_01626;MGYG000002438_03064;MGYG000002834_00630;MGYG000002614_01804;MGYG000004758_01030 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.12631578947368421 976|Bacteroidetes 1.0 P 0.9894736842105263 TonB-linked outer membrane protein, SusC RagA family 0.8315789473684211 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.5157894736842106 - 1.0 - 1.0 - 1.0 - 0.8526315789473684 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2966346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Asn->Thr)VMEIYGSK MGYG000002272_00822;MGYG000001300_00352;MGYG000002040_00733;MGYG000000022_01091;MGYG000003166_01369;MGYG000002545_02252;MGYG000002641_00365;MGYG000003899_00843 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 0.875 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 GABAergic synapse;Necroptosis;Glyoxylate and dicarboxylate metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Asn->Tyr)GVIIITTK MGYG000001787_01504;MGYG000002478_00526;MGYG000000196_04885;MGYG000002438_03064;MGYG000002438_02925;MGYG000003697_01696;MGYG000003697_02942;MGYG000000243_02417;MGYG000000013_00116 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.3333333333333333 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 0.8888888888888888 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2453599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Asn->Tyr)GVILITTK MGYG000002478_00836;MGYG000004748_01412;MGYG000003693_02459;MGYG000000013_01157;MGYG000002478_02338;MGYG000000196_04885;MGYG000002438_02656;MGYG000004703_01713;MGYG000002549_02801;MGYG000003697_01696;MGYG000003697_02942;MGYG000000105_01953;MGYG000001056_01040;MGYG000004899_00167;MGYG000003681_00932;MGYG000000224_02063;MGYG000001346_01792;MGYG000000174_02248;MGYG000001346_00980;MGYG000000029_03133;MGYG000000029_02281;MGYG000000003_01946;MGYG000003952_01841;MGYG000003693_01019;MGYG000001780_04788;MGYG000001378_04550;MGYG000002478_00526;MGYG000001661_01562;MGYG000000044_02806;MGYG000001661_00232;MGYG000001661_01167;MGYG000001306_00226;MGYG000002560_03505;MGYG000001345_04118;MGYG000003351_02635;MGYG000000196_04852;MGYG000001780_00424;MGYG000003367_00988;MGYG000000236_00670;MGYG000001489_01819;MGYG000000243_02417;MGYG000001783_00138;MGYG000000105_02058;MGYG000000781_02387;MGYG000003362_01220;MGYG000002455_01534;MGYG000002549_04362;MGYG000001789_02404;MGYG000003812_00487;MGYG000002293_00753;MGYG000001789_00624;MGYG000004797_01501;MGYG000002281_03192;MGYG000001489_03122;MGYG000000138_01670;MGYG000000044_02057;MGYG000001787_01504;MGYG000004876_00069;MGYG000002935_01014;MGYG000001345_03656;MGYG000000236_04565;MGYG000002478_02514;MGYG000002614_00404;MGYG000001056_00294;MGYG000004876_02160;MGYG000004006_01269;MGYG000003681_01449;MGYG000001666_00819;MGYG000004899_00413;MGYG000001378_02713;MGYG000001925_02044;MGYG000003493_02393;MGYG000000013_00116;MGYG000001503_01401;MGYG000004797_02606;MGYG000000138_01202;MGYG000001337_00935;MGYG000002438_02925;MGYG000001783_00512;MGYG000000224_00522;MGYG000003701_02338;MGYG000001599_02769;MGYG000000196_01084;MGYG000003681_02804;MGYG000002478_01281;MGYG000000105_01199;MGYG000001346_02872;MGYG000003363_00305;MGYG000001789_01698;MGYG000004899_00346;MGYG000004830_01626;MGYG000002438_03064;MGYG000002834_00630;MGYG000002614_01804;MGYG000004758_01030 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.12631578947368421 976|Bacteroidetes 1.0 P 0.9894736842105263 TonB-linked outer membrane protein, SusC RagA family 0.8315789473684211 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.5157894736842106 - 1.0 - 1.0 - 1.0 - 0.8526315789473684 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2709994 0 0 0 0 0 0 0 0 0 2202198 0 0 0 0 0 0 0 0 0 0 0 2964256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Asn->Xle)ATSLDQYK MGYG000000196_00573 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)AGGVATSALEMC(Carbamidomethyl)QNSAR MGYG000000184_00534;MGYG000003455_00764;MGYG000001338_02192 life d__Bacteria 0.6667 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 0.6666666666666666 C 0.6666666666666666 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 - 0.6666666666666666 1.4.1.3,1.4.1.4 0.6666666666666666 ko:K00261,ko:K00262 0.6666666666666666 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6666666666666666 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 783760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)AGGVATSALEMSQNSER MGYG000002945_01156;MGYG000000080_02138;MGYG000004689_01489;MGYG000000245_02477;MGYG000000135_03486;MGYG000004839_02530;MGYG000000251_03197;MGYG000000146_00040;MGYG000002212_01108;MGYG000000164_00589;MGYG000000153_01021;MGYG000004296_00383;MGYG000004380_02235;MGYG000000404_01723;MGYG000002517_02750;MGYG000001797_03050;MGYG000000312_01079;MGYG000001637_01313;MGYG000001689_00608;MGYG000000489_02253;MGYG000000280_02447;MGYG000002528_01412;MGYG000003425_04268;MGYG000000076_02271;MGYG000004879_02390;MGYG000000229_01813;MGYG000002670_01100;MGYG000000136_01003;MGYG000002609_02276;MGYG000004719_01514;MGYG000004547_00997;MGYG000003702_00540;MGYG000004055_01618;MGYG000003063_02071;MGYG000000187_02311;MGYG000002279_01299;MGYG000002149_01514;MGYG000002992_01902;MGYG000000271_00907;MGYG000002492_02848;MGYG000002131_02188 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.3170731707317073 186801|Clostridia 0.6829268292682927 C 0.4146341463414634 Belongs to the Glu Leu Phe Val dehydrogenases family 0.4634146341463415 gdhA 0.6829268292682927 - 1.0 1.4.1.3,1.4.1.4 0.6341463414634146 ko:K00261,ko:K00262 0.6341463414634146 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6341463414634146 M00740 0.6829268292682927 R00243,R00248 0.6829268292682927 RC00006,RC02799 0.6829268292682927 ko00000,ko00001,ko00002,ko01000,ko04147 0.6829268292682927 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.6829268292682927 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6341463414634146 0.6341463414634146 0.6341463414634146 0.6341463414634146 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.6341463414634146 none 1.0 0 0 0 2749364 0 0 0 0 0 730562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2491403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 944632 0 0 0 0 0 0 0 782005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)AGGVATSALEMSQNSMR MGYG000003142_02931;MGYG000000301_02376;MGYG000004022_00658;MGYG000001658_02349;MGYG000000201_03244;MGYG000003427_02564;MGYG000000142_02223;MGYG000002098_00876;MGYG000003012_01963 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.5555555555555556 186801|Clostridia 1.0 C 0.6666666666666666 Belongs to the Glu Leu Phe Val dehydrogenases family 0.7777777777777778 gdhA 0.8888888888888888 - 0.8888888888888888 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599756 0 0 0 0 0 0 0 -AAN(Deamidated)DINLK MGYG000004658_01702;MGYG000000074_00133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1415012 0 0 0 0 0 0 0 0 0 1865087 0 0 0 0 0 0 0 0 -AAN(Deamidated)DREFAK MGYG000000243_03128;MGYG000002560_00083;MGYG000000042_01472;MGYG000004797_03123;MGYG000001599_00128;MGYG000002478_01519 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1386197 0 0 0 0 0 0 0 0 0 853068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1014452 0 0 0 0 777876 0 0 161361 0 0 0 0 0 0 0 0 0 734733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276550 0 0 0 0 352160 0 0 232969 0 0 0 0 0 0 0 0 0 457740 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 195301 0 0 0 0 177831 0 0 0 0 0 0 0 0 0 0 0 0 48146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217138 0 0 0 0 232987 -AAN(Deamidated)DREFAKFADSIK MGYG000000243_03128 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)FEEVC(Carbamidomethyl)LGYNQEEAQAEAQR MGYG000000179_04744 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,21Y4Z@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 glutamate synthase (NADPH), homotetrameric 1.0 gltA 1.0 - 1.0 1.4.1.13,1.4.1.14 1.0 ko:K00266 1.0 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 1.0 - 1.0 R00093,R00114,R00248 1.0 RC00006,RC00010,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,NAD_binding_8,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate synthase (NADPH). | glutamate synthase (NADH). NADPH-glutamate synthase. | NADH-glutamate synthase. The reaction takes place in the opposite direction.-!-The protein is composed of two subunits, alpha and beta.-!-The alpha subunit is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.4).-!-The beta subunit transfers electrons from the cosubstrate.-!-The NH3 is channeled through a 31 A channel in the active protein.-!-In the absence of the beta subunit, coupling between the two domains of the alpha subunit is compromised and some ammonium can be produced.-!-In the intact alphabeta complex, ammonia production only takes place as part of the overall reaction.-!-Formerly EC 2.6.1.53. | A flavoprotein (FMN).-!-The reaction takes place in the direction of L-glutamate production.-!-The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2). 2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH. | 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH. 1.0 1.0 1.0 1.0 Nitrogen metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GNMVVVDK MGYG000001300_02214;MGYG000003899_00615;MGYG000003166_00760 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GNMVVVDKFAC(Carbamidomethyl)DEYK MGYG000001300_02214;MGYG000001255_02070;MGYG000003899_00615;MGYG000002545_01139;MGYG000002040_00971;MGYG000003166_00760 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1942816 1660281 0 0 0 1484712 1711382 0 0 1139303 0 1699949 0 1221988 1008251 0 0 0 0 0 0 0 1235841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 814233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GNMVVVDKFTC(Carbamidomethyl)DEYK MGYG000000022_02039 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226493 0 0 0 0 275029 0 0 0 0 154857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449981 0 0 0 0 407206 0 0 0 0 346726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 938534 0 0 0 0 1000471 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GSYYMANK MGYG000000133_00731 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1376@1|root,COG5263@1|root,COG1376@2|Bacteria,COG5263@2|Bacteria,1UVCF@1239|Firmicutes,24BKI@186801|Clostridia,3XZR4@572511|Blautia 1.0 186801|Clostridia 1.0 S 1.0 L,D-transpeptidase catalytic domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,YkuD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1841712 1030952 1467492 2296785 1646709 2188882 1505968 1334365 604611 1606394 1632709 1380844 857069 1466349 1361513 1291570 1856281 0 1715099 1775905 1202762 1195793 0 1206344 1597907 2623797 1508330 0 1828738 1579995 1711030 2560442 1521813 1869660 1471551 1881565 1993295 1683553 -AAN(Deamidated)GTLFR MGYG000002720_01381 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,2N6ZU@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GVASSAFTFQGQK MGYG000001315_00299 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the aldehyde dehydrogenase family 1.0 rocA 1.0 - 1.0 1.2.1.88 1.0 ko:K00294 1.0 ko00250,ko00330,ko01100,map00250,map00330,map01100 1.0 - 1.0 R00245,R00707,R00708,R04444,R04445,R05051 1.0 RC00080,RC00216,RC00242,RC00255 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Pro_dh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-glutamate gamma-semialdehyde dehydrogenase. pyrroline-5-carboxylate dehydrogenase. This enzyme catalyzes the irreversible oxidation of glutamate-gamma- semialdehyde to glutamate as part of the proline degradation pathway.-!-(S)-1-pyrroline-5-carboxylate, the product of the first enzyme of the pathway (EC 1.5.5.2) is in spontaneous equilibrium with its tautomer L-glutamate gamma-semialdehyde.-!-In many bacterial species, both activities are carried out by a single bifunctional enzyme.-!-The enzyme can also oxidize other 1-pyrrolines, e.g. 3-hydroxy-1- pyrroline-5-carboxylate is converted into 4-hydroxyglutamate and (R)- 1-pyrroline-5-carboxylate is converted into D-glutamate.-!-NADP(+) can also act as acceptor, but with lower activity.-!-Formerly EC 1.5.1.12. H2O + L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + L-glutamate + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Arginine and proline metabolism;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GVFDDANVQNR MGYG000002506_01355 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG3443@1|root,COG3443@2|Bacteria,1MXFK@1224|Proteobacteria,1RPWU@1236|Gammaproteobacteria,3XN2U@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 May function as a periplasmic zinc chaperone or mediate direct transport of zinc from the periplasm to the cytoplasm under zinc-limited conditions. Binds zinc with high affinity, and can also bind cadmium, mercury or nickel. Preferentially binds Zn(2 ) over Cd(2 ). Contains one high affinity metal binding site, and can bind additional metal ions at other sites 1.0 zinT 1.0 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0007154,GO:0008150,GO:0008270,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0030288,GO:0030313,GO:0031667,GO:0031668,GO:0031669,GO:0031975,GO:0033554,GO:0034224,GO:0042221,GO:0042594,GO:0042597,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0120127 1.0 - 1.0 ko:K09815 1.0 ko02010,map02010 1.0 M00242 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.15.3,3.A.1.15.5 1.0 - 1.0 - 1.0 ZinT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1210605 1513623 872165 0 1083638 2766685 1086598 1790411 1031521 1674999 0 1166010 0 1253273 1280407 0 1042509 0 1320558 0 1096778 2425909 0 1479525 1212945 1345625 1302892 0 1240932 1104209 0 1043376 950442 1508828 1507495 1130621 1263972 715865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GVIIITTK MGYG000001787_01504;MGYG000002478_00526;MGYG000000196_04885;MGYG000002438_03064;MGYG000002438_02925;MGYG000003697_01696;MGYG000003697_02942;MGYG000000243_02417;MGYG000000013_00116 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.3333333333333333 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 0.8888888888888888 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1369533 0 0 0 0 0 0 0 337218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1529048 0 0 0 0 0 0 0 898475 0 0 0 0 0 0 0 0 0 0 1152777 0 0 0 0 0 0 0 0 1180879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1253718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1201358 0 0 0 0 0 0 0 0 0 0 621948 0 0 0 0 0 0 3096480 0 0 0 0 0 0 1518276 0 0 0 -AAN(Deamidated)GVILITTK MGYG000002478_00836;MGYG000004748_01412;MGYG000003693_02459;MGYG000000013_01157;MGYG000002478_02338;MGYG000000196_04885;MGYG000002438_02656;MGYG000004703_01713;MGYG000002549_02801;MGYG000003697_01696;MGYG000003697_02942;MGYG000000105_01953;MGYG000001056_01040;MGYG000004899_00167;MGYG000003681_00932;MGYG000000224_02063;MGYG000001346_01792;MGYG000000174_02248;MGYG000001346_00980;MGYG000000029_03133;MGYG000000029_02281;MGYG000000003_01946;MGYG000003952_01841;MGYG000003693_01019;MGYG000001780_04788;MGYG000001378_04550;MGYG000002478_00526;MGYG000001661_01562;MGYG000000044_02806;MGYG000001661_00232;MGYG000001661_01167;MGYG000001306_00226;MGYG000002560_03505;MGYG000001345_04118;MGYG000003351_02635;MGYG000000196_04852;MGYG000001780_00424;MGYG000003367_00988;MGYG000000236_00670;MGYG000001489_01819;MGYG000000243_02417;MGYG000001783_00138;MGYG000000105_02058;MGYG000000781_02387;MGYG000003362_01220;MGYG000002455_01534;MGYG000002549_04362;MGYG000001789_02404;MGYG000003812_00487;MGYG000002293_00753;MGYG000001789_00624;MGYG000004797_01501;MGYG000002281_03192;MGYG000001489_03122;MGYG000000138_01670;MGYG000000044_02057;MGYG000001787_01504;MGYG000004876_00069;MGYG000002935_01014;MGYG000001345_03656;MGYG000000236_04565;MGYG000002478_02514;MGYG000002614_00404;MGYG000001056_00294;MGYG000004876_02160;MGYG000004006_01269;MGYG000003681_01449;MGYG000001666_00819;MGYG000004899_00413;MGYG000001378_02713;MGYG000001925_02044;MGYG000003493_02393;MGYG000000013_00116;MGYG000001503_01401;MGYG000004797_02606;MGYG000000138_01202;MGYG000001337_00935;MGYG000002438_02925;MGYG000001783_00512;MGYG000000224_00522;MGYG000003701_02338;MGYG000001599_02769;MGYG000000196_01084;MGYG000003681_02804;MGYG000002478_01281;MGYG000000105_01199;MGYG000001346_02872;MGYG000003363_00305;MGYG000001789_01698;MGYG000004899_00346;MGYG000004830_01626;MGYG000002438_03064;MGYG000002834_00630;MGYG000002614_01804;MGYG000004758_01030 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.12631578947368421 976|Bacteroidetes 1.0 P 0.9894736842105263 TonB-linked outer membrane protein, SusC RagA family 0.8315789473684211 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.5157894736842106 - 1.0 - 1.0 - 1.0 - 0.8526315789473684 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2083190 2216392 1795882 2002344 1798334 0 1711998 1405688 1851427 1483355 0 2140940 0 1987670 1719727 1918445 1921134 1028382 2352517 1888364 1625789 1566327 1246354 2545887 1520121 2062126 1692389 0 0 1932779 2180210 2888552 2313851 1371229 1997842 1847925 1783184 1598155 2253196 710342 0 1991891 1002803 870360 974747 1271045 1385071 0 990961 1124620 645319 0 1245115 1086559 893282 0 0 936308 0 1052523 2228602 723629 1115058 2011319 1683043 0 861936 801499 694669 1135513 1763260 1050909 1183159 1065822 1169851 0 1170737 1115559 0 973730 1583886 1259393 0 1186657 1312313 1373279 1422645 1648760 0 1142806 1259864 0 774326 942820 1246770 1154604 1082256 1010270 1042584 1129016 1203411 753525 1116288 0 1132360 1365977 1358727 1206452 2042423 970099 1358620 0 1184710 1811657 1959413 2224793 0 1359377 2206935 2353537 1399625 1984348 1999637 1818568 1340004 1904461 1551213 1645425 1908412 1728854 1693919 0 1544855 1299396 3936453 2057176 4526501 1713602 2022839 1898980 0 2365760 1719810 1955490 0 2523757 2260129 2082075 1768497 1873858 2068606 2106544 1158365 1017243 1064952 0 1781680 1927074 0 1628904 1906825 0 1899822 1351142 1630232 869136 1277479 1660528 1284796 0 1351435 1520669 886941 1440948 3164981 1938832 1534617 1314950 1046073 0 1219693 2118833 1311860 1443956 793522 1896539 0 977990 1631825 1246635 -AAN(Deamidated)GVILVTTK MGYG000000243_03100;MGYG000002478_00972;MGYG000004876_00726;MGYG000002478_00682;MGYG000001346_02823 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FW4E@200643|Bacteroidia 0.2 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6 - 1.0 - 1.0 - 1.0 - 0.8 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3863861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4037933 0 0 0 0 0 0 0 835856 0 0 -AAN(Deamidated)GVIMVTTKR MGYG000002438_02926 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,22ZXY@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552717 0 0 0 0 0 0 -AAN(Deamidated)GVIVITTK MGYG000004658_01775;MGYG000003152_00999;MGYG000000138_00500;MGYG000000236_03672;MGYG000004763_02090;MGYG000000183_00749;MGYG000004899_00261;MGYG000000183_02215;MGYG000001337_01441;MGYG000000273_01469;MGYG000000215_02004;MGYG000000243_03324;MGYG000001789_02910;MGYG000000168_01320;MGYG000000236_01565;MGYG000001666_00513;MGYG000002561_00966;MGYG000004748_03723;MGYG000001643_01406;MGYG000002478_01932;MGYG000001787_00685;MGYG000004797_01619;MGYG000001552_01556;MGYG000001925_01391;MGYG000004658_01327;MGYG000003374_00894;MGYG000001346_02589;MGYG000001337_01168;MGYG000001489_02092;MGYG000004797_04210;MGYG000001835_00475;MGYG000000183_02645;MGYG000003681_00349;MGYG000004876_03094;MGYG000001337_01171;MGYG000002203_00896;MGYG000002051_00947;MGYG000000168_02423;MGYG000000183_02880;MGYG000002478_02355;MGYG000000074_02074;MGYG000004468_01877;MGYG000004479_02279;MGYG000002933_00766;MGYG000001562_02517 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2G3FU@200643|Bacteroidia,4AV1P@815|Bacteroidaceae 0.2 976|Bacteroidetes 0.9777777777777777 P 0.9111111111111111 TonB-linked outer membrane protein, SusC RagA family 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.4444444444444444 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 4133527 4070898 7409471 3945906 5235366 3828682 3239598 3212242 3605658 2741025 384202 3225550 6513284 0 3129352 5916113 3587000 1600267 3656242 3538414 3358591 3227051 2652963 4559039 2884603 3564049 0 2549060 4440870 3469333 5689414 5034361 8114028 3768781 3493646 1047167 3507483 8756371 800755 638274 681126 496315 867850 550850 651028 763325 896343 707319 815351 0 1644116 876171 931353 1213350 432238 454505 627775 553382 664769 650973 0 280787 669606 816124 706438 698230 680543 547406 435077 955070 817484 152154 784985 904711 802334 627420 717492 953175 699975 796759 2113429 1901271 1362104 1412228 1714072 1452745 307184 1244419 3648129 0 1176430 2225409 463299 3157848 1582086 1132399 944760 944839 2765111 1575964 1231187 1270475 1049441 0 1314444 1296929 1509411 1249655 936339 940702 1672100 1496814 1306033 901085 1196776 0 299822 726570 0 828386 989501 559610 853558 860348 359697 1115622 1664723 927106 959405 919783 414046 745595 818587 760283 1342328 0 1096649 0 0 1455284 0 0 0 871645 0 440688 0 0 1006866 0 1497761 0 3021699 2283820 2638577 3386757 4383507 4408637 2410742 3224056 3814444 1927519 2040481 0 5544971 1989403 2736049 4763192 2925084 0 3263760 3556742 1472552 3238138 0 2968611 2436415 2459379 2296912 0 3233756 3849026 2608022 3280367 0 2879355 3039909 2123261 3455944 2884206 -AAN(Deamidated)GVIVITTKR MGYG000000243_03324 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GVIVLTTK MGYG000002478_01932;MGYG000000183_00749;MGYG000004763_02090;MGYG000001337_01168;MGYG000000183_02215;MGYG000001337_01441;MGYG000000183_02645;MGYG000001835_00475;MGYG000000243_03324;MGYG000001789_02910;MGYG000001337_01171;MGYG000000168_02147;MGYG000000168_02423;MGYG000000183_02880;MGYG000000168_01320;MGYG000002561_00966 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2G3FU@200643|Bacteroidia,4AV1P@815|Bacteroidaceae 0.1875 976|Bacteroidetes 0.9375 P 0.875 TonB-linked outer membrane protein, SusC RagA family 0.6875 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.5625 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 3852555 0 0 0 0 0 0 0 1116967 0 1332493 0 0 3499754 0 0 0 0 0 0 0 0 1125116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1378263 0 0 0 2253009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1264185 5720343 0 0 0 1353450 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GVIYITTK MGYG000004885_01473;MGYG000003460_00312;MGYG000000243_03196 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,1WDNI@1283313|Alloprevotella 0.6666666666666666 976|Bacteroidetes 1.0 P 1.0 Carboxypeptidase regulatory-like domain 0.6666666666666666 ragA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165113 0 0 0 0 0 0 0 0 0 0 701648 0 0 0 0 0 771314 1037584 0 0 0 0 0 0 0 0 0 0 0 0 0 1459731 0 0 0 0 1123484 858688 0 1216980 751976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236939 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GVIYITTKR MGYG000000243_03196 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 ragA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1789265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GVIYVQTK MGYG000001302.1_00590 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 ragA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 1227735 1075536 1101502 1352243 0 0 0 0 0 0 0 0 0 0 1384386 2620295 0 0 964585 1574028 1119732 0 0 0 1444051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463300 0 0 0 0 349315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 896001 1523173 1568443 1106758 0 0 0 0 0 0 0 0 0 0 2634774 1965045 0 0 607501 1865984 1335494 0 0 0 2145082 0 0 0 0 0 0 0 0 0 0 0 0 0 550685 516162 628577 461968 0 0 0 0 0 0 0 0 0 0 1206279 835409 0 0 494277 1604942 419594 0 0 0 330093 0 0 0 0 0 0 0 0 0 0 0 0 0 1639611 1313916 1697457 939915 0 0 0 0 0 0 0 0 0 0 3058099 1284708 0 0 944067 2568673 953251 0 0 0 2344850 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GVLLITTK MGYG000004797_02606;MGYG000001489_00601;MGYG000001489_00865;MGYG000001780_04788;MGYG000000196_04885;MGYG000002438_02925;MGYG000004899_01078;MGYG000000243_02417;MGYG000001783_00138;MGYG000001783_00512;MGYG000001925_01678;MGYG000004899_02902;MGYG000001925_00504;MGYG000001925_02673;MGYG000002834_00630;MGYG000002293_00753;MGYG000004797_01501 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.17647058823529413 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.8823529411764706 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.5294117647058824 - 1.0 - 1.0 - 1.0 - 0.7647058823529411 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1402958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4309533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)GVVFVTTK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 446981 0 465483 0 347373 162087 0 340055 0 500047 0 205533 0 342585 238896 563509 0 0 768921 548036 267687 487155 0 0 707943 507372 0 0 412573 490504 0 437804 352557 0 259173 433719 232348 232567 2425899 0 2036585 2626342 1476830 1179487 0 2723092 3013155 2635610 0 2188330 0 2903122 3474419 1265586 0 0 2363468 2516389 2094819 847772 0 908210 2184279 2976759 2414349 0 1948113 1889431 0 1806559 2390886 0 2420492 2494623 3692424 1913917 288024 0 203772 344018 223124 197323 0 373158 613918 274062 0 145030 0 275869 327774 233394 0 0 163946 493631 0 171136 0 216436 243156 274962 278227 0 279980 219038 0 211518 316629 0 280201 540234 436402 226585 561591 0 547041 402680 401539 242009 0 236291 0 526591 0 378754 0 438049 456237 0 0 0 675159 685850 718196 0 0 286973 513622 632543 866581 0 526208 452070 0 352530 0 0 601445 532401 560543 934233 494164 0 247436 219110 658773 284636 0 234371 470717 426089 0 217864 0 0 409871 274669 0 0 258101 671370 0 245917 0 426428 192949 423757 381097 0 373979 577980 0 560742 136370 0 350958 271239 497948 258387 -AAN(Deamidated)GVVIITTK MGYG000000042_01138;MGYG000002478_01456;MGYG000004876_03105 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4772@1|root,COG4772@2|Bacteria,4PM03@976|Bacteroidetes,2G09Q@200643|Bacteroidia,4AV6D@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1117822 0 0 0 0 403782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 708280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413209 1177067 241135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 606588 0 0 0 0 0 0 0 0 439704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683031 0 0 0 0 0 0 0 0 756528 0 0 0 732766 -AAN(Deamidated)GVVLITTK MGYG000002438_02058;MGYG000003697_00063;MGYG000001306_00077;MGYG000002438_00500;MGYG000002478_01456;MGYG000002960_00789;MGYG000002455_02640;MGYG000001780_01166;MGYG000000781_01695;MGYG000004876_02091;MGYG000003697_02396;MGYG000004797_02570;MGYG000001346_03464;MGYG000004899_00028;MGYG000000243_03191;MGYG000000196_00609;MGYG000002834_00176;MGYG000002478_02188;MGYG000004876_01524;MGYG000001643_02196;MGYG000001835_01972;MGYG000002171_01681;MGYG000004876_03105;MGYG000001643_01263 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.20833333333333334 976|Bacteroidetes 1.0 P 0.9166666666666666 TonB-linked outer membrane protein, SusC RagA family 0.7083333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 0.9166666666666666 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 2543503 0 0 0 0 0 0 0 0 0 0 0 933239 0 0 0 0 2302869 0 0 0 0 0 0 0 314949 0 0 547227 0 548818 0 0 197987 0 0 0 0 503234 1204314 0 0 0 0 0 0 0 0 714175 565611 2847356 479318 690434 659552 416141 0 0 875871 0 0 683489 541967 0 560978 698331 680886 0 0 0 0 0 819880 0 0 0 0 403176 534614 0 0 0 0 0 388421 0 0 460390 473534 275507 532816 0 544393 673842 257948 0 494839 0 632640 398362 0 0 0 657254 576343 516838 0 2543567 0 0 1260496 0 0 0 0 1182702 669265 0 0 0 0 0 967052 0 0 653702 1333086 929263 649851 1293371 698658 968025 344935 0 359745 0 607911 1835635 2081471 0 1103646 701100 0 776071 0 685008 0 0 1074715 0 0 0 0 477231 2580039 0 0 0 0 0 3100667 0 0 957480 606474 2867282 1147076 0 0 0 2307338 0 1632359 0 1142678 0 332036 0 662170 804370 0 -AAN(Deamidated)GVVMITTK MGYG000002478_01935;MGYG000000781_01691 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 515566 0 423408 636210 315260 0 0 404874 411436 0 0 284448 394062 691038 530862 0 0 0 0 575726 0 257294 0 0 0 893370 559638 0 0 376075 0 167208 422655 529248 716852 579818 700060 0 1874988 0 2079576 2003624 2579704 1758481 0 2399298 2023867 1981901 0 1819835 3791111 2126093 2311614 2478255 0 0 0 1804066 0 1582073 0 1309042 0 2091487 1926621 0 1828953 1704498 1331463 2153073 2371215 2278266 2565883 2453444 2583111 1822192 640026 0 457787 0 430958 0 0 0 0 0 0 843923 144178 0 267248 0 0 0 0 1924343 0 0 0 355664 0 0 0 0 374612 406200 531739 325337 313665 290866 1241071 462628 1213965 0 505407 0 0 364156 494256 549729 0 370319 585099 535063 0 477163 410715 0 600549 455277 0 0 0 450756 0 317437 0 0 0 583547 334646 0 0 530259 0 0 303719 571200 559648 431244 576681 0 0 0 0 0 963184 980297 0 0 0 450489 0 0 688900 429613 1466097 0 0 0 0 0 0 0 0 673963 0 594107 378837 0 0 486145 0 809566 0 0 638371 491331 0 0 -AAN(Deamidated)GVVMITTKK MGYG000002478_01935 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1042135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)LDAIHDTVHEM(Oxidation)AR MGYG000000123_00688;MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000002278_00133;MGYG000000139_02333;MGYG000000274_00102;MGYG000000249_00436;MGYG000000245_00992;MGYG000002702_00869;MGYG000004785_01880;MGYG000000076_00982;MGYG000002517_02838;MGYG000001560_01146;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000004263_01270;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000002837_00277;MGYG000000208_01702;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000000909_00619;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000004697_00836;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.45 186801|Clostridia 0.975 C 1.0 Rubrerythrin 0.6 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.975 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 906594 0 0 0 0 780027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1419654 0 721421 0 0 0 0 0 0 0 0 0 0 0 0 1106408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1476817 0 0 0 0 1146260 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1500499 0 0 0 1183798 0 0 0 0 0 0 0 0 0 0 831433 0 919145 0 0 0 0 495714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394766 0 671890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)LDAIHDTVHEM(Oxidation)ARDEAR MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000000139_02333;MGYG000000249_00436;MGYG000000245_00992;MGYG000000076_00982;MGYG000002517_02838;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.4482758620689655 186801|Clostridia 0.9655172413793104 C 1.0 Rubrerythrin 0.6551724137931034 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.9655172413793104 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)LDAIHDTVHEMAR MGYG000000123_00688;MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000002278_00133;MGYG000000139_02333;MGYG000000274_00102;MGYG000000249_00436;MGYG000000245_00992;MGYG000002702_00869;MGYG000004785_01880;MGYG000000076_00982;MGYG000002517_02838;MGYG000001560_01146;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000004263_01270;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000002837_00277;MGYG000000208_01702;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000000909_00619;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000004697_00836;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.45 186801|Clostridia 0.975 C 1.0 Rubrerythrin 0.6 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.975 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 867120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)LMLDAGAK MGYG000001661_00681;MGYG000001378_00980 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EF 1.0 COG0462 Phosphoribosylpyrophosphate synthetase 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2604318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)PTPEKPFVLGC(Carbamidomethyl)PTGSSPLGMYK MGYG000002171_00281;MGYG000002455_02070;MGYG000000196_01768;MGYG000001661_00842;MGYG000003351_04413;MGYG000002549_00225;MGYG000002478_04559;MGYG000002560_02540;MGYG000000243_00067;MGYG000001378_02954;MGYG000004876_00832;MGYG000000013_02920;MGYG000000029_00780 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,4AKMP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 593377 0 891210 0 0 0 0 0 0 0 0 0 0 0 0 0 291598 0 0 0 0 0 0 0 0 0 0 735906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518887 0 0 0 0 0 0 0 0 0 0 327725 0 0 0 0 0 0 0 0 0 0 436745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 680588 0 0 0 0 0 0 0 0 0 0 589449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 983188 0 1121603 0 0 0 0 0 0 0 0 0 0 0 0 0 229697 0 0 0 0 0 0 0 0 0 0 952272 0 0 -AAN(Deamidated)VALIGYEK MGYG000000198_03138;MGYG000001564_03639 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,2235C@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 CQ 1.0 BMC domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 1656526 0 0 0 1436305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1563244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 715771 0 0 0 1144285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)VIAK MGYG000000115_00663 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium_J|s__Clostridium_J sp902363375|m__MGYG000000115 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,36DMF@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 451918 0 0 0 0 0 0 393451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Deamidated)VTLVGK MGYG000000152_02876 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lacrimispora|s__Lacrimispora sp902363835|m__MGYG000000152 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 1.0 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2425866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAN(Methyl+Deamidated[N](Asn->Glu)VALVGTEK MGYG000000142_01601;MGYG000000301_01353;MGYG000000212_01002;MGYG000002312_02491;MGYG000003012_02044;MGYG000003822_02069;MGYG000000002_00289;MGYG000003821_00240;MGYG000000171_01279;MGYG000002772_00614;MGYG000000200_00386;MGYG000000263_00751;MGYG000001338_00128;MGYG000004785_00404;MGYG000000031_02918;MGYG000002186_00350;MGYG000000252_02288;MGYG000004733_01675;MGYG000002298_00401;MGYG000000216_00449 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.95 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.95 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3309875 0 0 0 0 0 0 0 0 0 0 0 0 3755964 0 0 0 0 0 0 0 0 0 0 0 2266153 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAAAQVEK MGYG000000074_00307;MGYG000000003_01005;MGYG000004658_02496 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 S 1.0 Histone H1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Hc1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 3874137 0 7109174 3638023 0 0 0 0 6615637 0 0 0 5151792 0 0 5115628 0 0 0 0 0 0 0 6859402 0 0 0 6344502 7785010 5317241 0 0 0 5423469 0 0 0 0 4736920 0 7431640 6200006 0 0 0 0 8900065 0 0 0 9264927 0 0 8609186 0 0 0 0 0 0 0 6700238 0 0 0 5496090 7746343 4559307 0 0 0 6123926 0 0 0 0 16881970 0 17355845 16096660 0 0 0 0 21221793 0 0 0 19499572 0 0 14863921 0 0 0 0 0 0 0 18411756 0 0 0 28585019 16340692 21017061 0 0 0 22179205 0 0 0 0 3329350 0 3315920 3109571 0 0 0 0 3309519 0 0 0 4179399 0 0 2974769 0 0 0 0 0 0 0 4172434 0 0 0 3404555 3631999 3239925 0 0 0 3989509 0 0 0 0 1182103 0 1858599 2089316 0 0 0 0 1764969 0 0 0 3045668 0 0 1630051 0 0 0 0 0 0 0 4245227 0 0 0 2306278 2989994 2316146 0 0 0 1684361 0 0 0 -AANAAFAK MGYG000001540_00252 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Mycobacteriales|f__Mycobacteriaceae|g__Corynebacterium|s__Corynebacterium provencense|m__MGYG000001540 1.0 COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,22JTF@1653|Corynebacteriaceae 1.0 201174|Actinobacteria 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3089906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAAYEPAR MGYG000000089_01614 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG1053@1|root,COG1053@2|Bacteria,2J6FD@203691|Spirochaetes 1.0 203691|Spirochaetes 1.0 C 1.0 PFAM fumarate reductase succinate dehydrogenase flavoprotein 1.0 - 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 928789 0 0 0 0 1578481 0 0 0 0 1199035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287613 0 0 0 0 785505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207727 0 0 0 0 0 0 0 0 0 0 -AANAEELEALR MGYG000002171_01913;MGYG000002438_03714;MGYG000000138_03867;MGYG000000243_00008;MGYG000004797_01609 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,2FNZN@200643|Bacteroidia,4AKA6@815|Bacteroidaceae 0.6 976|Bacteroidetes 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily 1.0 pheS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.20 1.0 ko:K01889 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Phe_tRNA-synt_N,tRNA-synt_2d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 275281 87009 226671 0 0 402417 0 0 242400 0 0 480689 0 221542 0 0 0 0 350410 0 248337 209744 0 393282 329257 486942 0 0 0 0 0 0 189499 0 0 0 310165 137970 665986 370581 752631 0 0 680753 0 0 672096 0 0 1294599 0 792672 0 0 0 0 745185 0 1090920 601755 0 537302 785736 854037 0 0 0 0 0 0 686735 0 0 0 706774 579300 208536 0 517678 0 0 437356 0 0 531073 0 0 618714 0 340474 0 0 0 0 458245 0 545967 0 0 419896 210718 231607 0 0 0 0 0 0 339641 0 0 0 342892 295430 435863 687931 1070626 0 0 260353 0 0 434557 0 0 986298 0 694476 0 0 0 0 393451 0 1342909 631570 0 447936 757438 891312 0 0 0 0 0 0 766574 0 0 0 780498 0 505552 236090 0 0 0 601818 0 0 603082 0 0 948605 0 380461 0 0 0 0 305506 0 1078644 423511 0 640822 537233 303867 0 0 0 0 0 0 295527 0 0 0 622957 217754 -AANAEIPIIFL MGYG000000029_00379;MGYG000001780_04718 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia,4AKWQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 1.0 rprY 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Response_reg,Trans_reg_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84605 0 0 0 0 0 0 0 95555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2684887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2568462 0 0 0 0 2096225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAEIPIIFLTAK MGYG000000196_03771;MGYG000000243_00835 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia,4AKWQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 1.0 rprY 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Response_reg,Trans_reg_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15060032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11829708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6681574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAGGVA(Ala->Thr)TSALEMSQNSER MGYG000002945_01156;MGYG000000080_02138;MGYG000004689_01489;MGYG000000245_02477;MGYG000000135_03486;MGYG000004839_02530;MGYG000000251_03197;MGYG000000146_00040;MGYG000002212_01108;MGYG000000164_00589;MGYG000000153_01021;MGYG000004296_00383;MGYG000004380_02235;MGYG000000404_01723;MGYG000002517_02750;MGYG000001797_03050;MGYG000000312_01079;MGYG000001637_01313;MGYG000001689_00608;MGYG000000489_02253;MGYG000000280_02447;MGYG000002528_01412;MGYG000003425_04268;MGYG000000076_02271;MGYG000004879_02390;MGYG000000229_01813;MGYG000002670_01100;MGYG000000136_01003;MGYG000002609_02276;MGYG000004719_01514;MGYG000004547_00997;MGYG000003702_00540;MGYG000004055_01618;MGYG000003063_02071;MGYG000000187_02311;MGYG000002279_01299;MGYG000002149_01514;MGYG000002992_01902;MGYG000000271_00907;MGYG000002492_02848;MGYG000002131_02188 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.3170731707317073 186801|Clostridia 0.6829268292682927 C 0.4146341463414634 Belongs to the Glu Leu Phe Val dehydrogenases family 0.4634146341463415 gdhA 0.6829268292682927 - 1.0 1.4.1.3,1.4.1.4 0.6341463414634146 ko:K00261,ko:K00262 0.6341463414634146 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6341463414634146 M00740 0.6829268292682927 R00243,R00248 0.6829268292682927 RC00006,RC02799 0.6829268292682927 ko00000,ko00001,ko00002,ko01000,ko04147 0.6829268292682927 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.6829268292682927 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6341463414634146 0.6341463414634146 0.6341463414634146 0.6341463414634146 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.6341463414634146 none 1.0 0 0 0 0 0 0 0 332542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724739 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 744822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAGGVATSALE(Cation_Na)MSQNSER MGYG000002945_01156;MGYG000000080_02138;MGYG000004689_01489;MGYG000000245_02477;MGYG000000135_03486;MGYG000004839_02530;MGYG000000251_03197;MGYG000000146_00040;MGYG000002212_01108;MGYG000000164_00589;MGYG000000153_01021;MGYG000004296_00383;MGYG000004380_02235;MGYG000000404_01723;MGYG000002517_02750;MGYG000001797_03050;MGYG000000312_01079;MGYG000001637_01313;MGYG000001689_00608;MGYG000000489_02253;MGYG000000280_02447;MGYG000002528_01412;MGYG000003425_04268;MGYG000000076_02271;MGYG000004879_02390;MGYG000000229_01813;MGYG000002670_01100;MGYG000000136_01003;MGYG000002609_02276;MGYG000004719_01514;MGYG000004547_00997;MGYG000003702_00540;MGYG000004055_01618;MGYG000003063_02071;MGYG000000187_02311;MGYG000002279_01299;MGYG000002149_01514;MGYG000002992_01902;MGYG000000271_00907;MGYG000002492_02848;MGYG000002131_02188 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.3170731707317073 186801|Clostridia 0.6829268292682927 C 0.4146341463414634 Belongs to the Glu Leu Phe Val dehydrogenases family 0.4634146341463415 gdhA 0.6829268292682927 - 1.0 1.4.1.3,1.4.1.4 0.6341463414634146 ko:K00261,ko:K00262 0.6341463414634146 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6341463414634146 M00740 0.6829268292682927 R00243,R00248 0.6829268292682927 RC00006,RC02799 0.6829268292682927 ko00000,ko00001,ko00002,ko01000,ko04147 0.6829268292682927 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.6829268292682927 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6341463414634146 0.6341463414634146 0.6341463414634146 0.6341463414634146 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.6341463414634146 none 1.0 0 0 0 0 0 0 0 0 0 0 0 3062492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3229349 0 0 0 0 0 0 0 0 0 0 0 0 0 3325033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1686139 0 0 0 0 0 0 0 0 0 0 0 0 0 1990309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1475996 0 0 0 0 0 0 0 0 0 0 0 0 0 573331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 817862 0 0 0 0 0 0 0 0 0 0 0 0 0 1676192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1240700 0 0 -AANAGGVATSALEM(Oxidation)SQNSER MGYG000002945_01156;MGYG000000080_02138;MGYG000004689_01489;MGYG000000245_02477;MGYG000000135_03486;MGYG000004839_02530;MGYG000000251_03197;MGYG000000146_00040;MGYG000002212_01108;MGYG000000164_00589;MGYG000000153_01021;MGYG000004296_00383;MGYG000004380_02235;MGYG000000404_01723;MGYG000002517_02750;MGYG000001797_03050;MGYG000000312_01079;MGYG000001637_01313;MGYG000001689_00608;MGYG000000489_02253;MGYG000000280_02447;MGYG000002528_01412;MGYG000003425_04268;MGYG000000076_02271;MGYG000004879_02390;MGYG000000229_01813;MGYG000002670_01100;MGYG000000136_01003;MGYG000002609_02276;MGYG000004719_01514;MGYG000004547_00997;MGYG000003702_00540;MGYG000004055_01618;MGYG000003063_02071;MGYG000000187_02311;MGYG000002279_01299;MGYG000002149_01514;MGYG000002992_01902;MGYG000000271_00907;MGYG000002492_02848;MGYG000002131_02188 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.3170731707317073 186801|Clostridia 0.6829268292682927 C 0.4146341463414634 Belongs to the Glu Leu Phe Val dehydrogenases family 0.4634146341463415 gdhA 0.6829268292682927 - 1.0 1.4.1.3,1.4.1.4 0.6341463414634146 ko:K00261,ko:K00262 0.6341463414634146 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6341463414634146 M00740 0.6829268292682927 R00243,R00248 0.6829268292682927 RC00006,RC02799 0.6829268292682927 ko00000,ko00001,ko00002,ko01000,ko04147 0.6829268292682927 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.6829268292682927 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6341463414634146 0.6341463414634146 0.6341463414634146 0.6341463414634146 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.6341463414634146 none 1.0 0 0 0 173802 0 0 0 0 0 0 0 0 0 0 386868 0 700439 1010608 0 0 0 0 390568 0 0 0 0 351164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224086 0 0 0 0 450654 0 0 0 0 443934 0 0 0 0 0 0 0 0 0 0 0 0 0 283688 0 0 0 0 0 0 0 0 0 0 324771 0 308967 339645 0 0 0 0 411152 0 0 0 0 485628 0 0 0 0 0 0 0 0 0 0 0 0 0 164179 0 0 0 0 0 0 0 0 0 0 405227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239860 0 0 0 0 0 0 0 0 0 0 362354 0 412743 253299 0 0 0 0 326326 0 0 0 0 290282 0 0 0 0 0 0 0 0 0 0 -AANAGGVATSALEMC(Carbamidomethyl)QNSAR MGYG000000184_00534;MGYG000003455_00764;MGYG000001338_02192 life d__Bacteria 0.6667 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 0.6666666666666666 C 0.6666666666666666 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 - 0.6666666666666666 1.4.1.3,1.4.1.4 0.6666666666666666 ko:K00261,ko:K00262 0.6666666666666666 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6666666666666666 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.6666666666666666 none 1.0 341531 1388575 859207 0 1017787 426936 440384 594295 0 0 1158103 0 960384 0 0 830240 568240 802701 0 0 0 373053 560523 0 0 321370 314568 1018752 0 453935 570631 1469228 480901 0 0 0 406118 486330 451747 2445146 0 0 793468 0 356777 390564 0 0 425175 0 419411 0 0 0 0 1579224 0 0 0 0 1106801 446496 0 0 567903 1202857 0 0 2479560 1110103 0 0 0 0 0 0 327964 2061289 525410 0 294586 0 339166 431880 0 0 334654 0 689183 0 0 508953 310830 0 0 0 0 544139 369080 0 0 0 344087 745396 0 537247 593803 1480163 973182 0 825964 0 555022 460954 0 0 0 0 0 0 0 0 0 0 415285 0 0 0 0 0 0 417020 0 0 0 0 0 0 0 0 0 0 0 346994 0 0 0 0 0 0 0 0 456153 4099456 2021592 0 980464 475614 734667 647025 0 0 781227 0 1110737 0 0 915338 289872 369078 0 0 0 636569 998146 531053 0 556234 638759 916132 0 690120 2517101 3261566 2934519 0 662116 0 525641 1670320 -AANAGGVATSALEMS(Methyl[S](Ser->Thr)QNSMR MGYG000003142_02931;MGYG000000301_02376;MGYG000004022_00658;MGYG000001658_02349;MGYG000000201_03244;MGYG000003427_02564;MGYG000000142_02223;MGYG000002098_00876;MGYG000003012_01963 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.5555555555555556 186801|Clostridia 1.0 C 0.6666666666666666 Belongs to the Glu Leu Phe Val dehydrogenases family 0.7777777777777778 gdhA 0.8888888888888888 - 0.8888888888888888 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449325 0 0 912375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1125216 0 1150439 0 0 0 0 0 0 0 0 1652732 0 0 0 0 342621 -AANAGGVATSALEMSQNSER MGYG000002945_01156;MGYG000000080_02138;MGYG000004689_01489;MGYG000000245_02477;MGYG000000135_03486;MGYG000004839_02530;MGYG000000251_03197;MGYG000000146_00040;MGYG000002212_01108;MGYG000000164_00589;MGYG000000153_01021;MGYG000004296_00383;MGYG000004380_02235;MGYG000000404_01723;MGYG000002517_02750;MGYG000001797_03050;MGYG000000312_01079;MGYG000001637_01313;MGYG000001689_00608;MGYG000000489_02253;MGYG000000280_02447;MGYG000002528_01412;MGYG000003425_04268;MGYG000000076_02271;MGYG000004879_02390;MGYG000000229_01813;MGYG000002670_01100;MGYG000000136_01003;MGYG000002609_02276;MGYG000004719_01514;MGYG000004547_00997;MGYG000003702_00540;MGYG000004055_01618;MGYG000003063_02071;MGYG000000187_02311;MGYG000002279_01299;MGYG000002149_01514;MGYG000002992_01902;MGYG000000271_00907;MGYG000002492_02848;MGYG000002131_02188 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.3170731707317073 186801|Clostridia 0.6829268292682927 C 0.4146341463414634 Belongs to the Glu Leu Phe Val dehydrogenases family 0.4634146341463415 gdhA 0.6829268292682927 - 1.0 1.4.1.3,1.4.1.4 0.6341463414634146 ko:K00261,ko:K00262 0.6341463414634146 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6341463414634146 M00740 0.6829268292682927 R00243,R00248 0.6829268292682927 RC00006,RC02799 0.6829268292682927 ko00000,ko00001,ko00002,ko01000,ko04147 0.6829268292682927 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.6829268292682927 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6341463414634146 0.6341463414634146 0.6341463414634146 0.6341463414634146 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.6341463414634146 none 1.0 3989835 3366014 2810549 6051349 3713600 3569569 2938878 4322387 3677901 4336497 6913253 3578488 4499371 3145359 3602268 4008419 4350661 5607156 2436534 4342940 4146698 3500212 5657905 0 3832789 3865581 4408982 7081206 3848953 4116513 0 2631203 2048673 3046141 3948950 3277806 3785112 2028602 1505172 2369460 1464547 1761049 1861562 1287654 1399179 1646284 1294988 1347692 1254482 1211568 1569278 1544454 1380094 1526392 1409936 8526149 1251799 1701014 1363231 1286229 5718090 1936941 1254440 1630426 1327235 8633214 2939276 1556874 2779737 1741309 1340293 1423786 1426826 1479323 1546734 1429297 5305855 2499009 4111579 3755561 1943745 2051315 3204351 3739540 2688372 6192752 2690546 3926573 2936750 3709994 4978641 3612024 4384966 2375792 3283226 4440256 3286480 2917467 3862560 2441044 4041494 7986301 4367297 5985550 3107649 3274742 1991245 3062881 4712213 4161761 3941398 3086467 4771621 3565469 2434771 1590887 642440 2141923 1221595 578376 1108181 1981924 2477806 618891 948024 1367751 620098 2742917 2583548 1352671 2038046 1658877 1359263 1725663 2965576 408816 1343612 527331 2804301 2067468 1004670 546925 426222 1514639 670639 1588633 603758 1585700 2527233 2203154 2368751 609030 4366490 5912803 8171822 919572 2500537 5724961 4434235 4340166 4455011 9549044 4903449 5955747 2496993 6895172 10414742 4874909 9219738 3507835 7127665 3553485 4301299 5174686 4195899 4968588 5607251 4356549 6177467 4279433 4645735 3087871 5313681 2204329 7155005 4902962 4727411 7336397 6548432 5275373 -AANAGGVATSALEMSQNSMR MGYG000003142_02931;MGYG000000301_02376;MGYG000004022_00658;MGYG000001658_02349;MGYG000000201_03244;MGYG000003427_02564;MGYG000000142_02223;MGYG000002098_00876;MGYG000003012_01963 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.5555555555555556 186801|Clostridia 1.0 C 0.6666666666666666 Belongs to the Glu Leu Phe Val dehydrogenases family 0.7777777777777778 gdhA 0.8888888888888888 - 0.8888888888888888 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 257021 368324 584838 332787 512194 620203 164543 767402 0 556040 1362118 492501 375409 0 334279 493136 829364 260879 0 349991 490600 348340 491837 168735 385402 126618 350059 756112 261272 656754 0 180454 444902 451046 352959 279211 249783 460327 660516 1014440 682736 487588 1283147 522760 1101660 849933 0 613381 1584629 464600 725034 448202 388212 491437 483934 817779 553186 849016 210330 0 520115 0 567108 817599 1569355 749303 787232 853941 0 1025165 821511 1029886 901474 1056483 721791 773007 602743 626125 578871 328837 279479 460520 409139 496528 0 329276 371523 434825 488901 339486 507205 451108 314603 0 357608 396925 285395 702896 396791 365441 519477 451385 451256 596376 436233 365679 329738 474135 1039678 671690 496583 245637 557549 415074 251656 253793 0 0 388499 0 0 0 0 0 0 0 0 82630 248721 0 225305 0 0 0 0 0 0 0 0 0 0 0 0 220479 0 155738 0 0 0 0 0 0 624943 613723 807864 642452 193854 671292 777871 573511 0 1134860 1014510 900923 293969 1240815 982438 349087 676299 315995 835525 274484 909766 0 425293 938831 915626 596271 1080983 580039 1079565 217410 789139 721033 1818795 734856 658652 888830 568812 840307 -AANAGGVATSALEMSQNSQR MGYG000004285_01380;MGYG000004642_00466;MGYG000000278_03573;MGYG000000258_01047;MGYG000000171_00025 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.6 186801|Clostridia 1.0 C 0.8 Belongs to the Glu Leu Phe Val dehydrogenases family 0.8 gdhA 0.8 - 1.0 1.4.1.3,1.4.1.4 0.8 ko:K00261,ko:K00262 0.8 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.8 M00740 0.8 R00243,R00248 0.8 RC00006,RC02799 0.8 ko00000,ko00001,ko00002,ko01000,ko04147 0.8 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.8 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.8 0.8 0.8 0.8 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.8 none 1.0 339755 0 313940 231144 0 361083 386123 233890 0 797278 0 425154 232006 0 374920 272912 0 0 321683 306762 0 435995 0 230083 419452 476776 365966 0 525987 321989 0 439462 0 400402 0 419553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164898 0 0 524001 0 0 0 0 473133 0 0 138060 196517 305358 0 0 0 0 0 0 0 0 0 0 1381444 0 721733 839939 0 738462 754221 962660 0 835709 0 931029 864242 0 974907 908054 0 484140 863715 1170609 0 1199179 1220573 743384 1071660 1086008 1071574 1118520 726867 891287 0 586384 976476 1094765 1317640 776982 1203063 976326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112047 0 0 0 0 0 0 0 0 0 0 0 0 249339 0 0 0 0 183896 0 0 0 0 0 0 0 0 0 0 0 0 0 355620 -AANAGGVATSALEMSQNSQRLSWTFEEVDAK MGYG000000036_02065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Pseudoruminococcus|s__Pseudoruminococcus massiliensis|m__MGYG000000036 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,268E7@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdhA 1.0 - 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 1456585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAGGVATSGLEM(Oxidation)SQNSER MGYG000002074_01624;MGYG000000089_00679;MGYG000002881_00615;MGYG000002274_02026 domain d__Bacteria 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae 0.5 186801|Clostridia 0.75 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 0.75 gdhA 0.5 - 1.0 1.4.1.3,1.4.1.4 0.5 ko:K00261,ko:K00262 0.5 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.5 - 0.5 R00243,R00248 0.5 RC00006,RC02799 0.75 ko00000,ko00001,ko01000 0.5 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.75 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.5 0.5 0.5 0.5 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670801 0 0 0 0 396766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAGGVATSGLEMAQNAAR MGYG000002502_02076;MGYG000002506_01152;MGYG000002534_02260;MGYG000002323_01826;MGYG000002494_01678;MGYG000002477_03414 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria 0.6666666666666666 1236|Gammaproteobacteria 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.3,1.4.1.4 0.6666666666666666 ko:K00261,ko:K00262 0.6666666666666666 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6666666666666666 M00740 0.6666666666666666 R00243,R00248 0.6666666666666666 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 0.6666666666666666 - 1.0 - 1.0 iECH74115_1262.ECH74115_2481,iECSP_1301.ECSP_2329,iECs_1301.ECs2467,iG2583_1286.G2583_2207,iPC815.YPO3971,iSDY_1059.SDY_1514,iYL1228.KPN_01210,iZ_1308.Z2793 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 96429 0 0 0 165744 0 0 0 0 0 460323 1184115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155389 0 0 1312787 1437772 1932113 0 2001357 1639758 1547449 638130 841929 2233583 0 0 1653772 1817902 661494 2112396 2803380 0 10585677 1753015 3110391 2065721 0 1825675 2586009 979792 825047 0 4405809 3434167 0 0 2209542 799012 725717 1201433 832466 1657536 0 0 314727 0 0 633648 130664 0 0 0 0 0 0 0 0 0 0 0 1125972 528456 0 629696 0 345284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306731 0 0 0 0 0 0 0 0 0 0 0 0 0 487235 331990 392120 0 346094 0 0 0 0 0 0 232130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAGGVATSGLEMSQNSER MGYG000002074_01624;MGYG000000089_00679;MGYG000002881_00615;MGYG000002274_02026 domain d__Bacteria 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae 0.5 186801|Clostridia 0.75 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 0.75 gdhA 0.5 - 1.0 1.4.1.3,1.4.1.4 0.5 ko:K00261,ko:K00262 0.5 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.5 - 0.5 R00243,R00248 0.5 RC00006,RC02799 0.75 ko00000,ko00001,ko01000 0.5 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.75 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.5 0.5 0.5 0.5 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 0.5 none 1.0 0 0 0 0 0 0 460080 0 0 0 0 0 0 0 0 0 0 2271368 0 0 0 0 3117722 0 0 0 0 2391600 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850011 0 0 0 0 748873 0 0 0 0 963878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168354 0 0 0 0 0 0 0 0 0 0 403567 0 0 0 0 590093 0 0 0 0 857431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 357290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184733 0 0 0 0 0 0 0 0 0 0 949867 0 0 0 0 1422642 0 0 0 0 1374226 0 0 0 0 0 0 0 0 0 0 -AANAGGVATSGLEMSQNSLR MGYG000003937_01839 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 - 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 475191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 835622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAGGVATSGLEMTQNSMR MGYG000000074_01576;MGYG000004658_01015 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,22V1Z@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366548 0 0 0 0 0 0 0 0 0 0 0 0 0 703566 0 0 0 855859 0 0 0 0 0 0 1780043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 487867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 637984 0 0 0 0 0 0 0 0 0 0 0 0 0 964493 0 0 0 0 0 0 0 0 0 0 737932 0 0 0 0 0 0 0 -AANAGGVATSGLEQSQNALR MGYG000004087_01470;MGYG000000198_05072;MGYG000000179_02572;MGYG000001954_01682;MGYG000001311_01200 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,268E7@186813|unclassified Clostridiales 0.8 186801|Clostridia 1.0 E 0.8 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 0.8 gdhA 1.0 - 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 1129606 0 0 732094 0 0 505751 0 636621 633028 0 0 0 994890 815555 118958 531220 0 527491 1300058 841123 259269 0 0 485364 645922 445102 0 1005973 0 0 0 0 323879 0 1003105 684836 0 0 0 0 248737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194762 0 0 0 0 0 0 234411 223274 0 385566 0 0 0 0 0 0 249884 166849 0 1161447 0 301180 1576220 0 289510 679743 0 742355 835825 0 516615 0 834229 1247524 393190 857779 0 723990 876610 743465 667971 0 0 187064 1084574 1057017 0 672149 0 0 0 402728 849305 0 930074 844563 501487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 834870 603842 977233 1606024 0 352073 986065 0 1012781 1098537 0 965898 0 1925966 1103951 551352 1195288 0 635517 727767 1075936 853173 0 1322106 940639 1113858 1532227 0 1704877 0 807613 0 1416277 1130232 0 1380183 1047231 865979 -AANAGGVATSGLEQSQNSLR MGYG000000242_02251 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,268E7@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdhA 1.0 - 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Necroptosis;Proximal tubule bicarbonate reclamation;Carbon metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 943905 0 0 0 0 1136453 0 0 0 0 0 0 0 0 0 0 -AANAGGVAVSGLEMSQNSER MGYG000001056_01499;MGYG000002603_01071;MGYG000003493_00641;MGYG000001770_00555;MGYG000003697_02127;MGYG000002293_02206 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294361 0 0 0 0 123773 0 0 0 0 0 0 0 0 0 0 0 468310 578481 0 0 222599 540922 0 526993 0 0 0 241989 0 346754 0 0 0 0 0 0 654293 171276 0 424861 711866 621634 0 0 501916 854691 0 747300 204742 374096 267325 0 426964 1092561 976792 3820077 0 1405517 2439892 1029451 1162056 1043390 0 3608860 979041 1858284 883421 1177913 1377831 0 4221458 0 0 795873 4001075 6148145 2192147 1339851 1271588 1023928 1358967 0 870140 1102121 1227296 2916850 1283199 1122950 1333239 1181499 2462002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAGGVAVSGLEMSQNSMR MGYG000000254_02292;MGYG000000168_02503 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Marinifilaceae 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,22WFZ@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 - 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 1205640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400722 0 0 589589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 434695 0 0 0 0 560849 0 0 0 0 388643 0 0 0 0 0 0 0 0 0 0 0 0 0 572219 0 0 0 0 0 0 0 0 0 0 0 0 0 727812 0 0 0 0 685297 0 0 0 0 279818 0 0 503219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365494 0 0 0 0 0 0 0 0 0 0 0 0 0 583443 0 0 0 0 576496 0 0 0 0 517351 0 0 0 0 0 0 0 0 0 0 -AANAGGVAVSGLEMSQNSYR MGYG000003683_01480 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4CYTN@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 301025 0 0 0 0 0 0 0 0 0 178528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379533 0 0 0 0 0 0 0 0 0 0 0 866790 0 0 0 0 210434 771470 0 0 0 340478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314475 0 0 0 0 0 0 0 0 0 0 0 1431550 0 0 0 0 0 0 0 0 0 766227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAGGVSVSGLEM(Oxidation)TQNSIK MGYG000003693_00557;MGYG000001313_03295;MGYG000001789_00079;MGYG000002549_04353;MGYG000001370_01162;MGYG000000098_03405;MGYG000003312_01614;MGYG000001787_01270;MGYG000000415_01192;MGYG000001378_04299;MGYG000000196_02414;MGYG000000043_00874;MGYG000002455_00090;MGYG000002561_00600;MGYG000001461_03124;MGYG000000029_00569;MGYG000001346_00984;MGYG000001599_00620;MGYG000000042_02165;MGYG000000236_00945;MGYG000004797_02295;MGYG000000243_02148;MGYG000004899_01533;MGYG000002281_02120;MGYG000001835_02312;MGYG000002478_00271 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AKTV@815|Bacteroidaceae 0.8461538461538461 976|Bacteroidetes 1.0 C 0.8461538461538461 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 453520 0 0 0 0 499852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 370707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 415018 0 0 0 0 364230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 708631 0 0 0 0 299026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAGGVSVSGLEMSQNSER MGYG000002540_00149 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Paraprevotella|s__Paraprevotella clara|m__MGYG000002540 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAGGVSVSGLEMTQN(Deamidated)SIK MGYG000003693_00557;MGYG000001313_03295;MGYG000001789_00079;MGYG000002549_04353;MGYG000001370_01162;MGYG000000098_03405;MGYG000003312_01614;MGYG000001787_01270;MGYG000000415_01192;MGYG000001378_04299;MGYG000000196_02414;MGYG000000043_00874;MGYG000002455_00090;MGYG000002561_00600;MGYG000001461_03124;MGYG000000029_00569;MGYG000001346_00984;MGYG000001599_00620;MGYG000000042_02165;MGYG000000236_00945;MGYG000004797_02295;MGYG000000243_02148;MGYG000004899_01533;MGYG000002281_02120;MGYG000001835_02312;MGYG000002478_00271 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AKTV@815|Bacteroidaceae 0.8461538461538461 976|Bacteroidetes 1.0 C 0.8461538461538461 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 323617 0 363430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 620616 0 803748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 462379 0 387839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640487 0 679934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANAGGVSVSGLEMTQNAQK MGYG000002438_00724;MGYG000002575_00603 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,22XFA@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 0 0 0 0 296802 0 0 0 0 0 0 661983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292451 0 0 0 0 0 0 1579716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394228 0 0 0 0 0 0 0 431043 0 0 0 0 0 0 0 0 0 366299 415113 0 0 2509826 0 0 0 0 0 0 316912 0 0 0 0 366167 0 0 0 553615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 925902 0 0 1176617 0 0 0 0 0 0 2345596 736929 0 0 1111141 0 995502 0 0 3492903 0 957751 0 0 0 0 878555 0 3028819 0 3121821 0 0 0 0 0 0 -AANAGGVSVSGLEMTQNSIK MGYG000003693_00557;MGYG000001313_03295;MGYG000001789_00079;MGYG000002549_04353;MGYG000001370_01162;MGYG000000098_03405;MGYG000003312_01614;MGYG000001787_01270;MGYG000000415_01192;MGYG000001378_04299;MGYG000000196_02414;MGYG000000043_00874;MGYG000002455_00090;MGYG000002561_00600;MGYG000001461_03124;MGYG000000029_00569;MGYG000001346_00984;MGYG000001599_00620;MGYG000000042_02165;MGYG000000236_00945;MGYG000004797_02295;MGYG000000243_02148;MGYG000004899_01533;MGYG000002281_02120;MGYG000001835_02312;MGYG000002478_00271 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AKTV@815|Bacteroidaceae 0.8461538461538461 976|Bacteroidetes 1.0 C 0.8461538461538461 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism 1.0 none 1.0 1400842 1684854 4566249 1743347 2560685 1606063 1776330 1147943 1460758 1154817 5885749 1255740 5150784 1024834 823646 2950110 1348476 836425 783660 871662 1152474 1267474 1699027 1652206 940217 1383429 1431277 1496521 1337011 1511896 2721467 1725834 5185023 1281142 1134743 1544079 1405978 4786631 782075 931844 1279919 1153077 2843556 1489996 1004468 785879 940698 1115017 6891194 1278949 7303127 1117278 1022487 3432920 1356473 1622238 831079 940464 1078388 1813838 2382902 1414519 1023048 1247425 1210839 1878893 1056538 1193157 1089883 1411040 0 730051 993564 1092543 886984 1151646 1060426 839678 2133591 1648401 2165184 2085109 1630735 1114718 1677566 984056 6665501 1359797 4612409 1264656 1038780 2799698 0 3628907 1082471 932058 953440 1145869 3163030 1412354 947987 1276627 1179914 2493139 1040835 1217022 1590969 903777 1504756 1057881 1344658 1596843 1512365 2087771 384395 0 301493 0 0 384855 424897 334781 168761 0 1045898 527159 1107490 393659 419731 354118 0 54784 0 0 456794 0 799009 0 666701 569836 400585 0 0 0 112767 0 0 753910 495789 409573 420512 0 799860 902026 837147 1167200 1610899 1599378 1198056 959273 1433034 969647 8380406 1319930 8113162 1056679 1091796 3412144 1342046 3563542 771546 1147465 921847 1473983 3132963 1909071 1206304 1271266 1099586 2517388 1152667 1702125 1328001 1213462 915051 1242653 1336836 1161208 2115411 1282968 -AANAIDALK MGYG000003514_00092 genome d__Bacteria|p__Fibrobacterota|c__Fibrobacteria|o__Fibrobacterales|f__Fibrobacteraceae|g__Fibrobacter_A|s__Fibrobacter_A intestinalis|m__MGYG000003514 1.0 COG0459@1|root,COG0459@2|Bacteria 1.0 2|Bacteria 1.0 O 1.0 protein refolding 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1,Response_reg 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis;Tuberculosis;Type I diabetes mellitus;RNA degradation;Longevity regulating pathway - worm 1.0 none 1.0 2165502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2566673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANASYYPGVR MGYG000003697_00736 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2G3FU@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150458 0 0 161327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1045856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1073066 0 0 0 0 1199711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANATQVVK MGYG000003697_02150;MGYG000002603_01099 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0246@1|root,COG0246@2|Bacteria,4NEMT@976|Bacteroidetes,2FP8Z@200643|Bacteroidia,4ATAV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Mannitol dehydrogenase Rossmann domain 1.0 uxuB 1.0 - 1.0 1.1.1.17,1.1.1.58,1.1.1.67 1.0 ko:K00009,ko:K00041,ko:K00045 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00631 1.0 R00868,R02555,R02703 1.0 RC00085 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Mannitol_dh,Mannitol_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 mannitol-1-phosphate 5-dehydrogenase. | tagaturonate reductase. | mannitol 2-dehydrogenase. Tagaturonate dehydrogenase. | mannitol dehydrogenase. - D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + H(+) + NADH. | D-altronate + NAD(+) = H(+) + keto-D-tagaturonate + NADH. | D-mannitol + NAD(+) = D-fructose + H(+) + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 236777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 344791 0 169271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7289156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13389018 0 12619542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANATSFEQYK MGYG000001346_01072 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1397537 549946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675292 0 0 0 0 0 339805 1155586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336255 0 0 0 0 0 0 0 0 0 0 0 958174 0 0 0 0 0 2089124 724532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877981 0 0 0 0 0 0 0 0 0 0 0 374302 0 0 0 0 0 568438 598441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256879 0 0 0 0 0 0 0 0 0 0 0 579526 0 0 0 0 0 2994815 876640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 731118 0 0 0 0 0 0 0 -AANATSFNQYK MGYG000001345_01176;MGYG000001378_02418 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 330791 0 0 0 0 1160525 0 0 0 0 0 0 0 0 0 0 252185 0 410772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218190 0 0 0 0 698332 0 0 0 0 0 0 0 0 0 0 144387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403549 0 0 0 0 407612 0 0 0 0 0 0 0 0 0 0 271243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488905 0 0 0 0 923635 0 0 0 0 0 0 0 0 0 0 620461 0 501719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANDDLLNSFWLLDSEKGEAR MGYG000002534_03664;MGYG000002494_04114 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3445@1|root,COG3445@2|Bacteria,1RDRB@1224|Proteobacteria,1S45G@1236|Gammaproteobacteria,3X2H1@547|Enterobacter 0.5 1236|Gammaproteobacteria 1.0 S 1.0 Acts as a radical domain for damaged PFL and possibly other radical proteins 1.0 grcA 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.0 - 1.0 ko:K06866 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 iSF_1195.SF2641,iSFxv_1172.SFxv_2898,iS_1188.S2814 1.0 Gly_radical 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 38219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1419123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANDELSK MGYG000002438_03857 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG2885@1|root,COG2885@2|Bacteria,4NKQC@976|Bacteroidetes,2FRBK@200643|Bacteroidia,22X13@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 - 1.0 GO:0001871,GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0006810,GO:0008150,GO:0015267,GO:0015288,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030246,GO:0030247,GO:0051179,GO:0051234,GO:0055085 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 780579 288164 454919 0 162201 409824 1046448 320870 619957 831868 572096 1857784 0 0 0 407335 436440 382849 830690 0 106885 386064 186604 1175950 0 594837 679058 118690 0 612547 0 662648 288361 0 696285 885186 398486 244091 728569 353718 1146128 0 814541 859258 742809 1347194 912161 1062234 1225332 5550749 0 0 0 944560 834417 169644 484532 0 4748079 427583 314989 914768 0 1611853 1280126 870139 0 3979918 0 1789853 332816 0 916244 639913 1122914 899237 164452 746680 506354 0 593933 580234 283527 0 324239 518198 542278 909355 0 0 0 491418 445202 43010 593378 0 4086191 451747 273015 449086 0 345349 443116 124252 0 1223639 0 1270913 425359 0 0 507613 532150 424660 437613 760818 394471 0 0 555510 446959 93105 522513 0 469899 1452969 0 0 0 513806 419917 340305 644342 0 2497391 392754 0 485622 0 819389 723534 1875776 0 1711878 0 1541970 358593 0 257377 185908 633424 395094 2438735 1923638 1174243 0 2593182 1152801 2188775 1679983 2416476 2582761 3786432 3192857 0 0 0 2547393 1517654 3251513 1684600 0 10002959 1912354 3000778 2258703 0 2981996 2845811 1101769 0 6952350 0 2447978 961704 0 4870697 2987175 3422778 2363932 -AANDIN(Deamidated)LKALNK MGYG000004658_01702;MGYG000000074_00133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2099476 0 0 0 0 0 0 0 0 0 0 0 0 1894221 0 0 0 0 0 0 0 0 0 0 0 0 2354356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANDINLK MGYG000004658_01702;MGYG000000074_00133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 438026 127477 575378 0 339886 0 0 0 0 0 269834 0 402144 602066 234780 0 126725 76106 437986 0 0 0 0 269310 0 0 0 0 319196 363668 0 0 0 0 85435 780019 4290749 2802561 4440930 4394456 3000720 2264579 2459726 3590288 5226431 3774733 0 3353168 1716433 0 3895377 2943514 3129340 0 3795412 5386300 3755301 2253195 0 1636251 2441694 3405608 3895699 0 0 3459318 2157716 2925410 4016368 0 4878951 0 162073 4257418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1863511 892058 1653581 1683124 1709783 1325622 2145845 1532844 1660848 1371167 0 1787025 622515 0 2202468 875877 1409815 0 1870461 2297860 1608010 0 0 0 1477132 1860700 1573412 0 0 2102292 972146 1429213 1760893 0 2457611 0 1837303 666966 13079119 9178732 15322063 21581114 25492069 23209888 15788160 11726503 21172496 14176828 0 14957173 19150682 0 11878058 16377225 14618665 0 18613634 29125453 11236875 15143756 0 13436519 17250926 28237938 9386213 0 0 28321729 14865280 9288345 6838922 0 9666610 0 20112628 17632440 -AANDLILSK MGYG000003452_00078 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium ruminantium|m__MGYG000003452 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6552063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANDLVLSK MGYG000001490_00318;MGYG000001292_02366;MGYG000003683_01140;MGYG000002469_01773 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 6172664 0 0 0 0 0 0 0 0 0 973005 0 0 0 0 6197456 0 0 0 0 0 0 0 0 0 0 1707682 0 1223666 0 4385990 340718 0 473335 0 5077036 0 2553600 13960103 0 0 4877325 0 0 0 0 0 0 3611223 0 0 0 0 8061336 0 0 0 3098099 0 7862888 0 0 0 6513362 1907243 0 12050032 0 10715512 1904707 0 1720938 0 19589903 0 1738561 5098553 0 0 1262961 0 0 0 0 0 0 0 0 0 0 0 1205346 0 0 0 1434241 1657187 1195590 0 0 0 0 1350340 0 1806859 0 13161344 2456207 0 1110475 0 5264186 0 0 0 0 0 633602 0 0 0 0 0 0 960095 0 0 0 0 3728631 0 0 0 0 475496 1096948 0 0 0 0 0 0 0 0 0 920159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613608 0 0 0 0 0 0 0 291714 0 411398 0 0 0 0 0 -AANDMGVIC(Carbamidomethyl)GVTTNPSLIAK MGYG000001338_02857 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,3XYWX@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 1170690 914389 853398 959002 616668 0 1238966 0 0 0 0 1065676 0 0 901077 801784 454360 0 0 0 778950 811784 426878 0 0 0 939170 915565 0 0 0 418240 0 0 0 0 540688 0 1685899 0 459309 0 140829 0 376765 0 0 0 0 388025 0 0 0 0 1330643 0 0 0 0 1153263 588677 0 0 0 1250947 0 0 0 0 0 0 0 0 0 0 0 1057689 0 820264 0 0 0 480360 0 0 0 0 0 0 0 571959 482741 237271 0 0 0 0 473114 0 0 0 0 245104 0 0 0 0 0 0 0 0 0 835282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127755 0 0 0 199353 0 0 0 0 0 278031 0 0 0 0 0 0 0 0 0 0 0 1152798 624742 1258791 226784 508609 655539 342101 0 0 0 0 1061011 0 0 488617 300278 435948 0 0 0 298411 762716 276069 0 0 0 981492 306261 0 0 0 1130121 0 0 0 0 916024 -AANDREFAK MGYG000000243_03128;MGYG000002560_00083;MGYG000000042_01472;MGYG000004797_03123;MGYG000001599_00128;MGYG000002478_01519 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 7131782 6430957 21999907 11428533 13224300 7434972 10589449 6629847 8902639 7200836 8445654 8790134 12902140 8369809 9246900 15186018 9436505 10081698 7915084 6203334 9134560 9309550 10794552 12713898 9022923 9430068 8299525 11439343 8467449 11223243 19723440 10651940 21924482 8608634 9998947 10040861 7523362 19054460 3468621 3128622 3635865 4256146 6661151 4147549 4182209 4496745 3007720 4221556 5936039 4372545 10172970 4294451 4923255 8071664 4608697 2008981 4054517 3654396 4681449 4765035 3216607 3348429 3860525 4629429 4298228 3531856 4252296 4354815 3243589 5027590 4089606 2717114 3748000 3279874 3589262 2923234 2129893 3520750 3828804 3916669 5740462 4843807 2460410 2878085 4183276 3198164 3763534 3729080 8361748 3681318 3279460 5628762 2973909 2262995 3901029 3202153 2950201 3499751 4062972 5784757 3124843 3962701 3367640 6743294 4617213 1913232 5691371 2988964 2841059 1735796 3358658 4561123 3954205 4109214 558310 862507 630606 523882 1086844 1031750 566349 754406 665265 866439 574439 570916 270321 737801 624070 580567 565889 266799 920383 536840 153319 569204 43065 295371 555133 774757 735789 378904 878260 716776 950702 1319608 1173580 312113 785225 619006 787061 719877 3496098 2653732 2762884 3151596 7626288 3679517 3160641 3277483 4744212 1639159 3327840 2282845 7007020 2776287 3350139 5090733 2896398 5580904 3251208 3284781 1725162 2791394 5473062 3303692 3438429 5677423 3082029 2831334 3251025 2227225 3956340 3358305 2577312 3715805 7432241 4987220 5581390 3612641 -AANDREFAKFADSIK MGYG000000243_03128 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANDREFAKYADAIK MGYG000004797_03123;MGYG000002478_01519 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANDSGIC(Carbamidomethyl)K MGYG000000806_02507;MGYG000000133_01552;MGYG000000301_00312;MGYG000002966_01860 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 COG NOG14451 non supervised orthologous group 1.0 - 1.0 - 1.0 2.7.4.25 1.0 ko:K00945 1.0 ko00240,ko01100,map00240,map01100 1.0 M00052 1.0 R00158,R00512,R01665 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 (d)CMP kinase. deoxycytidylate kinase. The prokaryotic cytidine monophosphate kinase specifically phosphorylates CMP (or dCMP), using ATP as the preferred phosphoryl donor.-!-Unlike EC 2.7.4.14, a eukaryotic enzyme that phosphorylates UMP and CMP with similar efficiency, the prokaryotic enzyme phosphorylates UMP with very low rates, and this function is catalyzed in prokaryotes by EC 2.7.4.22.-!-The enzyme phosphorylates dCMP nearly as well as it does CMP. (1) ATP + CMP = ADP + CDP. (2) ATP + dCMP = ADP + dCDP. 1.0 1.0 1.0 1.0 Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 329916 220195 578324 516814 0 440230 669578 322649 685200 418425 307053 0 174947 772042 442524 217820 557735 0 0 0 520103 753012 0 534298 475857 111839 586184 0 560220 0 408784 602289 465684 487036 0 150223 515688 605590 0 0 0 0 0 0 0 115956 234743 221187 0 0 0 286097 0 0 373966 0 0 0 0 0 0 206788 127440 385033 0 0 401336 0 284245 283468 85673 91209 0 80993 0 97011 467596 1209263 258118 853166 0 0 0 778401 0 773164 451228 0 719305 564104 693759 0 373136 0 0 0 633838 737077 0 271343 755447 235814 196503 0 285287 0 952975 0 634865 571431 0 684338 0 622693 224150 388192 219165 214390 0 213006 0 0 338567 201495 164023 0 0 261738 235473 168405 870259 0 0 0 0 0 0 157091 0 362160 230673 0 145599 0 0 239095 279722 446608 0 0 216929 0 1440197 1249005 877001 1063185 0 342289 1879019 761021 801585 1782642 1915378 0 815462 2524276 1120496 722573 948104 0 0 0 2104525 833150 0 765794 1123869 1084390 2132678 0 1212434 0 825908 600445 2239529 1236442 0 1582333 915867 872337 -AANEGEKTETVVK MGYG000001636_01005;MGYG000002775_01401;MGYG000000188_00094;MGYG000003122_01642;MGYG000002050_00255;MGYG000002970_01301;MGYG000002968_01697;MGYG000003266_00528;MGYG000002961_01014;MGYG000004681_00342 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CWB2@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 - 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 2760153 0 0 1141487 0 0 0 0 0 1547813 0 0 0 0 1642197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365904 0 0 369675 0 0 0 0 0 723993 0 0 0 0 129915 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477606 0 0 0 0 0 0 0 0 229740 0 0 0 0 1124729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640842 0 0 1645117 0 0 0 0 0 2244185 0 0 0 0 3266359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71497 0 0 0 0 0 0 0 0 374499 0 0 0 0 267984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANEGEKTETVVKK MGYG000002775_01401;MGYG000003122_01642;MGYG000002978_01270;MGYG000000333_00407;MGYG000002961_01014;MGYG000004681_00342;MGYG000001718_00765;MGYG000000802_00126;MGYG000001636_01005;MGYG000000188_00094;MGYG000002050_00255;MGYG000002947_00311;MGYG000003274_00534;MGYG000002970_01301;MGYG000002968_01697;MGYG000003266_00528;MGYG000004875_00527;MGYG000002065_00129 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CWB2@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 - 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 3916012 1056183 0 1154668 1063517 0 948449 0 0 2217900 0 2979561 0 0 3431071 922552 0 0 750912 0 1225195 0 0 976517 0 0 0 771248 673972 824407 0 491604 0 0 0 0 759646 0 236860 156334 0 505906 257070 0 476279 0 0 829577 0 720162 0 0 412891 0 0 0 294426 0 114542 0 510247 347523 0 0 0 502820 374250 993895 0 0 0 0 0 0 175767 0 921841 351112 0 0 340439 0 576632 0 0 233945 0 801147 0 0 1209493 1071976 0 0 645531 0 512762 0 119768 397022 0 0 0 503675 505859 151487 0 500066 0 0 0 0 300890 0 770434 758336 0 1673974 776529 0 535164 0 0 2513765 0 2470953 0 0 4740363 935722 0 0 773117 0 1972194 0 1181900 855734 0 0 0 1717067 1203582 867352 0 835309 0 0 0 0 948499 0 113942 189134 0 0 75476 0 146245 0 0 646094 0 658495 0 0 299976 88677 0 0 0 0 0 0 0 205558 0 0 0 217728 0 323974 0 500776 0 0 0 0 243642 -AANEIIDAAGGDEAKPTGEN(Deamidated)GVYFAQAK MGYG000001306_00078;MGYG000001835_01971 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG3193@1|root,COG3193@2|Bacteria,4P0RZ@976|Bacteroidetes,2G0AC@200643|Bacteroidia,4AV3N@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525588 0 0 0 0 520308 0 0 0 0 565793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 639187 0 0 0 0 467995 0 0 0 0 526664 0 0 0 0 0 0 0 0 0 0 -AANELGYPVLVRPSYVLGGQGMR MGYG000000216_00641;MGYG000000142_00537;MGYG000001338_00548 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3WG9X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 978636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANEQQIK MGYG000000089_00234 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG1882@1|root,COG1882@2|Bacteria,1VBNT@1239|Firmicutes,24MR3@186801|Clostridia,27NYF@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Glycine radical 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Gly_radical 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 990772 0 0 0 0 1230642 0 0 0 0 870880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221941 0 0 0 0 385361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 404144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANESFGYNEDEIVSSDIVGMR MGYG000000262_01195;MGYG000002517_01026;MGYG000002492_01379;MGYG000001652_01009;MGYG000000489_00503 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216475 0 0 0 0 0 0 0 0 0 0 0 0 167452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585615 0 850135 908313 687939 0 765358 0 615014 0 0 638603 0 0 0 2291677 0 0 446828 429852 1485302 683303 0 0 0 1513797 0 0 793771 0 463992 0 0 626181 0 639679 0 0 0 0 0 253812 0 0 170023 0 163393 0 0 197167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182538 0 0 0 0 129473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANESGLW(Dioxidation)NVTVQLK MGYG000000243_01886;MGYG000002171_01694 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANESGLWNVTVQLK MGYG000000243_01886;MGYG000002171_01694 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2370989 0 8444221 4475836 3143333 2045109 3627990 3168207 2469152 2152013 2733366 2327737 3386965 1640216 1768619 1900770 2581985 1006765 2118563 2095231 1976838 1639374 1725835 1556546 2271964 2465100 2909492 2238019 3007104 3338542 4708427 3525057 9504103 3429120 3003065 2977939 2499469 6576101 0 0 0 0 0 0 0 0 0 0 0 0 204481 0 171526 148376 0 0 0 0 0 0 0 367976 0 0 0 0 0 0 162264 277551 0 0 0 60411 0 0 1816225 0 529718 1130226 795659 383090 778909 1206161 484634 1198877 598851 989164 1668414 777120 2017039 1336266 1383308 1381201 2127515 1594504 1091153 1160081 1458258 746776 948800 1917211 2059225 2422922 872763 1475867 530540 1222287 1653732 1298133 2650786 1024481 1455551 638813 65083 0 76178 72291 72005 170600 70010 482908 58965 81224 211897 0 59219 460756 388541 123250 85035 0 435963 170838 92252 0 0 93869 139868 0 512379 0 315713 161009 292601 268924 71838 0 0 364428 466932 150323 0 0 116865 102041 0 0 0 0 0 0 0 0 0 0 100103 0 150937 0 0 0 0 0 0 130356 0 0 121025 0 0 0 0 49871 211870 0 0 0 0 0 -AANEVEEDR MGYG000000044_01042;MGYG000000174_02677 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 558254 0 0 393545 0 0 0 0 799264 0 1252674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1277880 867590 0 454154 1314306 0 0 0 167731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1438368 1024973 0 1218256 0 0 0 0 865634 0 1056955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 991859 2008422 0 1083551 1681274 0 0 0 1272602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANEVEEDRAFLIESNVEPK MGYG000000044_01042 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides merdae|m__MGYG000000044 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 2619191 0 0 0 3382020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2846260 0 0 0 2915843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295398 0 0 0 206844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399602 0 0 0 0 0 0 0 0 0 0 0 261834 0 0 0 321838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 634218 0 0 0 301247 0 0 0 0 -AANFEEVC(Carbamidomethyl)LGYNQEEAQAEAQR MGYG000000179_04744 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,21Y4Z@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 glutamate synthase (NADPH), homotetrameric 1.0 gltA 1.0 - 1.0 1.4.1.13,1.4.1.14 1.0 ko:K00266 1.0 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 1.0 - 1.0 R00093,R00114,R00248 1.0 RC00006,RC00010,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,NAD_binding_8,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate synthase (NADPH). | glutamate synthase (NADH). NADPH-glutamate synthase. | NADH-glutamate synthase. The reaction takes place in the opposite direction.-!-The protein is composed of two subunits, alpha and beta.-!-The alpha subunit is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.4).-!-The beta subunit transfers electrons from the cosubstrate.-!-The NH3 is channeled through a 31 A channel in the active protein.-!-In the absence of the beta subunit, coupling between the two domains of the alpha subunit is compromised and some ammonium can be produced.-!-In the intact alphabeta complex, ammonia production only takes place as part of the overall reaction.-!-Formerly EC 2.6.1.53. | A flavoprotein (FMN).-!-The reaction takes place in the direction of L-glutamate production.-!-The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2). 2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH. | 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH. 1.0 1.0 1.0 1.0 Nitrogen metabolism;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 561327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507641 0 0 0 0 0 0 0 0 0 0 477406 0 -AANGN(Deamidated)MILVDKIAADEYK MGYG000003921_00344 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191004 0 0 0 0 346929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 197480 0 0 0 0 330776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633024 0 0 0 0 736908 0 0 0 0 1071142 0 0 0 0 0 0 0 0 0 0 -AANGN(Deamidated)MVVVDK MGYG000001300_02214;MGYG000003899_00615;MGYG000003166_00760 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANGN(Deamidated)MVVVDKFAC(Carbamidomethyl)DEYK MGYG000001300_02214;MGYG000001255_02070;MGYG000003899_00615;MGYG000002545_01139;MGYG000002040_00971;MGYG000003166_00760 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 334888 472559 355893 592870 0 223587 0 85994 259063 0 380472 0 0 0 0 288443 0 0 0 0 0 145378 0 389331 0 306455 0 0 0 0 263798 104236 451550 513663 0 0 278186 402639 1270173 831935 1139386 1401544 695074 1145193 0 900089 1354675 0 697808 0 0 0 0 1162194 0 0 0 0 0 1293879 0 1121750 0 1369341 0 0 0 0 866883 1073612 1228763 1313531 0 0 1413171 1056542 352301 0 333391 141003 481293 322578 0 269951 211700 0 321289 0 0 0 0 277818 0 0 0 0 0 235231 0 435209 0 357896 0 0 0 0 184575 185660 0 407684 0 0 260517 304125 85940 239482 483090 297651 401274 237693 0 0 220764 0 319905 0 0 0 0 364558 0 0 0 0 0 252360 0 366761 0 329626 0 0 0 0 208510 116475 201160 537706 0 0 287768 277890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANGN(Deamidated)MVVVDKFTC(Carbamidomethyl)DEYK MGYG000000022_02039 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 943669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANGNMILVDKIAADEYK MGYG000003921_00344 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443563 0 0 0 0 631207 0 0 0 0 650630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327683 0 0 0 0 366317 0 0 0 0 236634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 653275 0 0 0 0 619159 0 0 0 0 683156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581509 0 0 0 0 689517 0 0 0 0 880687 0 0 0 0 0 0 0 0 0 0 -AANGNMVVVDKFAC(Carbamidomethyl)DEYK MGYG000001300_02214;MGYG000001255_02070;MGYG000003899_00615;MGYG000002545_01139;MGYG000002040_00971;MGYG000003166_00760 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 660701 0 0 0 934085 0 941232 0 0 0 0 0 0 0 403178 0 717150 0 0 0 0 0 0 0 0 0 0 0 0 0 443571 0 0 0 0 529799 0 0 1170293 0 0 0 1367120 0 1148242 0 0 0 0 0 0 0 1320664 0 1229666 0 0 0 0 0 0 0 0 0 0 0 0 0 978714 0 0 0 0 926603 0 0 436106 0 0 0 641601 0 361824 0 0 0 0 0 0 0 363976 0 299806 0 0 0 0 0 0 0 0 0 0 0 0 0 278561 0 0 0 0 534573 0 0 546048 0 0 0 746881 0 503012 0 0 0 0 0 0 0 585339 0 364805 0 0 0 0 0 0 0 0 0 0 0 0 0 498035 0 0 0 0 473830 0 0 583631 0 0 0 431099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 126976 0 0 0 0 0 -AANGSYYMANK MGYG000000133_00731 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1376@1|root,COG5263@1|root,COG1376@2|Bacteria,COG5263@2|Bacteria,1UVCF@1239|Firmicutes,24BKI@186801|Clostridia,3XZR4@572511|Blautia 1.0 186801|Clostridia 1.0 S 1.0 L,D-transpeptidase catalytic domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,YkuD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1159240 0 271802 1147739 0 1048553 0 0 462360 1227318 0 0 1357065 1088375 0 697879 1008321 0 0 1889536 0 934325 0 668739 0 1502647 919210 0 1143847 0 1186813 705529 827374 871764 0 1448747 1342163 1318384 -AANGVFDDANVQNR MGYG000002506_01355 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG3443@1|root,COG3443@2|Bacteria,1MXFK@1224|Proteobacteria,1RPWU@1236|Gammaproteobacteria,3XN2U@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 May function as a periplasmic zinc chaperone or mediate direct transport of zinc from the periplasm to the cytoplasm under zinc-limited conditions. Binds zinc with high affinity, and can also bind cadmium, mercury or nickel. Preferentially binds Zn(2 ) over Cd(2 ). Contains one high affinity metal binding site, and can bind additional metal ions at other sites 1.0 zinT 1.0 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0007154,GO:0008150,GO:0008270,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0030288,GO:0030313,GO:0031667,GO:0031668,GO:0031669,GO:0031975,GO:0033554,GO:0034224,GO:0042221,GO:0042594,GO:0042597,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0120127 1.0 - 1.0 ko:K09815 1.0 ko02010,map02010 1.0 M00242 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.15.3,3.A.1.15.5 1.0 - 1.0 - 1.0 ZinT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1657773 1399452 1069103 0 1074417 2663627 1601993 1519149 1377066 2068008 0 1585851 0 1203247 1606825 0 1416663 0 0 0 1391955 2428344 0 2260729 1936430 1494453 1192368 0 1373230 1396640 0 1940437 994955 1655068 2056262 1395820 1082005 776255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302079 0 0 0 0 -AANGVIIITTK MGYG000001787_01504;MGYG000002478_00526;MGYG000000196_04885;MGYG000002438_03064;MGYG000002438_02925;MGYG000003697_01696;MGYG000003697_02942;MGYG000000243_02417;MGYG000000013_00116 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.3333333333333333 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 0.8888888888888888 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1665743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1991136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385196 0 0 0 0 0 0 0 1687859 0 0 0 0 0 219588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1258695 0 0 0 0 0 0 0 0 0 0 0 0 0 1154130 0 0 0 0 744637 0 0 0 0 0 0 0 0 1227435 0 0 0 0 0 0 6520168 0 0 0 0 0 1581694 543041 0 994216 0 -AANGVILITTK MGYG000002478_00836;MGYG000004748_01412;MGYG000003693_02459;MGYG000000013_01157;MGYG000002478_02338;MGYG000000196_04885;MGYG000002438_02656;MGYG000004703_01713;MGYG000002549_02801;MGYG000003697_01696;MGYG000003697_02942;MGYG000000105_01953;MGYG000001056_01040;MGYG000004899_00167;MGYG000003681_00932;MGYG000000224_02063;MGYG000001346_01792;MGYG000000174_02248;MGYG000001346_00980;MGYG000000029_03133;MGYG000000029_02281;MGYG000000003_01946;MGYG000003952_01841;MGYG000003693_01019;MGYG000001780_04788;MGYG000001378_04550;MGYG000002478_00526;MGYG000001661_01562;MGYG000000044_02806;MGYG000001661_00232;MGYG000001661_01167;MGYG000001306_00226;MGYG000002560_03505;MGYG000001345_04118;MGYG000003351_02635;MGYG000000196_04852;MGYG000001780_00424;MGYG000003367_00988;MGYG000000236_00670;MGYG000001489_01819;MGYG000000243_02417;MGYG000001783_00138;MGYG000000105_02058;MGYG000000781_02387;MGYG000003362_01220;MGYG000002455_01534;MGYG000002549_04362;MGYG000001789_02404;MGYG000003812_00487;MGYG000002293_00753;MGYG000001789_00624;MGYG000004797_01501;MGYG000002281_03192;MGYG000001489_03122;MGYG000000138_01670;MGYG000000044_02057;MGYG000001787_01504;MGYG000004876_00069;MGYG000002935_01014;MGYG000001345_03656;MGYG000000236_04565;MGYG000002478_02514;MGYG000002614_00404;MGYG000001056_00294;MGYG000004876_02160;MGYG000004006_01269;MGYG000003681_01449;MGYG000001666_00819;MGYG000004899_00413;MGYG000001378_02713;MGYG000001925_02044;MGYG000003493_02393;MGYG000000013_00116;MGYG000001503_01401;MGYG000004797_02606;MGYG000000138_01202;MGYG000001337_00935;MGYG000002438_02925;MGYG000001783_00512;MGYG000000224_00522;MGYG000003701_02338;MGYG000001599_02769;MGYG000000196_01084;MGYG000003681_02804;MGYG000002478_01281;MGYG000000105_01199;MGYG000001346_02872;MGYG000003363_00305;MGYG000001789_01698;MGYG000004899_00346;MGYG000004830_01626;MGYG000002438_03064;MGYG000002834_00630;MGYG000002614_01804;MGYG000004758_01030 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.12631578947368421 976|Bacteroidetes 1.0 P 0.9894736842105263 TonB-linked outer membrane protein, SusC RagA family 0.8315789473684211 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.5157894736842106 - 1.0 - 1.0 - 1.0 - 0.8526315789473684 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2101002 1728761 2454030 2674743 1711009 2030971 2350468 1259865 2179580 1774597 0 1971712 0 2382763 1608791 1922945 2568007 1305085 1581053 1808257 1774273 2193491 0 2660441 1687397 2354328 2285861 0 1733911 1903136 2955435 1654441 2720715 0 1855405 2387248 2142263 2558526 777614 2109155 0 0 0 0 0 1257235 4462487 1010045 0 877316 0 0 0 2061024 0 3334041 0 0 0 0 4678809 0 0 0 2868591 3159685 619931 2493587 2571978 1298977 0 0 1511014 3525779 4008851 0 0 815655 1029001 1408252 1699066 0 0 818244 1417298 799508 1439249 1755147 676916 1123211 1032154 0 971090 0 761422 813880 1188672 998242 0 1875034 1088844 1155044 712186 2293586 1236858 921689 1934911 1008647 1141211 862598 869560 0 1307043 1349679 1070902 0 1432751 1162294 1300785 1139157 1256045 1159384 1275330 961156 790623 1417277 1142494 899533 1014082 680079 952507 1115247 1044864 954419 2522190 985092 2198024 355581 1045780 1262333 1097245 404233 599080 1185254 0 1860476 860454 1285251 1043644 1336789 1039685 809652 1381086 986448 1038465 1391225 1471503 1311434 1128966 1357919 1218122 701205 1481767 999379 1169159 888412 1101618 1421761 1120322 0 1255591 1811204 578933 1303379 3781541 778660 1140543 1002385 904925 0 1255620 1247224 1337152 864066 540064 0 1099102 384645 1015538 1466747 -AANGVILVTTK MGYG000000243_03100;MGYG000002478_00972;MGYG000004876_00726;MGYG000002478_00682;MGYG000001346_02823 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FW4E@200643|Bacteroidia 0.2 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6 - 1.0 - 1.0 - 1.0 - 0.8 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545941 0 0 0 0 0 0 0 0 1322388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2481327 0 0 0 0 0 0 0 0 0 0 -AANGVIMVTTKR MGYG000002438_02926 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,22ZXY@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1901310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANGVIVITTK MGYG000004658_01775;MGYG000003152_00999;MGYG000000138_00500;MGYG000000236_03672;MGYG000004763_02090;MGYG000000183_00749;MGYG000004899_00261;MGYG000000183_02215;MGYG000001337_01441;MGYG000000273_01469;MGYG000000215_02004;MGYG000000243_03324;MGYG000001789_02910;MGYG000000168_01320;MGYG000000236_01565;MGYG000001666_00513;MGYG000002561_00966;MGYG000004748_03723;MGYG000001643_01406;MGYG000002478_01932;MGYG000001787_00685;MGYG000004797_01619;MGYG000001552_01556;MGYG000001925_01391;MGYG000004658_01327;MGYG000003374_00894;MGYG000001346_02589;MGYG000001337_01168;MGYG000001489_02092;MGYG000004797_04210;MGYG000001835_00475;MGYG000000183_02645;MGYG000003681_00349;MGYG000004876_03094;MGYG000001337_01171;MGYG000002203_00896;MGYG000002051_00947;MGYG000000168_02423;MGYG000000183_02880;MGYG000002478_02355;MGYG000000074_02074;MGYG000004468_01877;MGYG000004479_02279;MGYG000002933_00766;MGYG000001562_02517 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2G3FU@200643|Bacteroidia,4AV1P@815|Bacteroidaceae 0.2 976|Bacteroidetes 0.9777777777777777 P 0.9111111111111111 TonB-linked outer membrane protein, SusC RagA family 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.4444444444444444 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2361123 2052075 5379367 3121514 4200389 2709582 3387752 1648199 2563149 0 2091019 0 4443303 0 1741607 3335087 2572267 1752572 1546460 1791495 2712507 0 2369998 3854824 1853778 2388487 0 2238033 3046646 0 6171080 2372215 5742365 2202568 2668510 0 2996989 6791554 624300 282904 387402 920687 511247 288990 336722 352181 0 519578 495985 453235 706412 392695 401188 696234 359903 381712 434914 457567 173045 328016 640351 160529 391914 349708 341404 373325 308123 318021 405224 267229 399299 315230 502406 576771 368234 418105 1117322 394877 1153090 1183429 2013554 1495348 1593692 0 1706992 945330 1283312 926563 1948465 1290459 0 1903134 898537 2102751 895691 933920 973450 799411 1634831 1833504 0 1090139 0 0 1227126 1218716 1605905 737862 736189 900810 1035707 1553657 1203806 0 701003 540409 458109 698645 389067 0 754692 633193 451699 753941 446881 524670 742115 530597 721905 482127 528497 398343 490270 557547 568933 277703 0 0 748828 730001 636582 0 523828 605871 0 515917 242526 909554 698965 886118 580609 0 1994302 1371669 1276942 1751645 2679067 1981125 1460706 2251971 1822751 980222 851205 958286 3108074 1084010 1458256 2554832 1665598 0 1877467 3015227 1043506 2070517 0 1718019 1414065 1200804 1335975 0 2005315 1871945 1656603 1495755 851303 0 1872190 1483519 1545226 1370921 -AANGVIVLTTK MGYG000002478_01932;MGYG000000183_00749;MGYG000004763_02090;MGYG000001337_01168;MGYG000000183_02215;MGYG000001337_01441;MGYG000000183_02645;MGYG000001835_00475;MGYG000000243_03324;MGYG000001789_02910;MGYG000001337_01171;MGYG000000168_02147;MGYG000000168_02423;MGYG000000183_02880;MGYG000000168_01320;MGYG000002561_00966 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2G3FU@200643|Bacteroidia,4AV1P@815|Bacteroidaceae 0.1875 976|Bacteroidetes 0.9375 P 0.875 TonB-linked outer membrane protein, SusC RagA family 0.6875 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.5625 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 2623393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3213897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1246427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANGVIYIT(Thr->Asn)TK MGYG000004885_01473;MGYG000003460_00312;MGYG000000243_03196 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,1WDNI@1283313|Alloprevotella 0.6666666666666666 976|Bacteroidetes 1.0 P 1.0 Carboxypeptidase regulatory-like domain 0.6666666666666666 ragA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1353486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1002552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 880302 0 0 0 0 0 0 0 0 0 -AANGVIYVQTK MGYG000001302.1_00590 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 ragA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 440451 0 635959 633069 877448 0 0 0 0 0 0 0 0 0 0 722020 984068 0 0 357401 862926 827711 0 0 0 651683 0 0 0 0 512855 0 0 0 0 602466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 967592 0 1141039 867145 982199 0 0 0 0 0 0 0 0 0 0 1614756 1024404 0 0 631101 1693735 999268 0 0 0 684022 0 0 0 0 568802 0 0 0 0 833949 0 0 0 0 0 0 258250 0 0 0 0 0 0 0 0 0 0 521911 504412 0 0 0 343129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 627965 0 807839 0 725204 0 0 0 0 0 0 0 0 0 0 2063030 1016798 0 0 484081 1805865 751520 0 0 0 1779289 0 0 0 0 423349 0 0 0 0 599829 -AANGVLLITTK MGYG000004797_02606;MGYG000001489_00601;MGYG000001489_00865;MGYG000001780_04788;MGYG000000196_04885;MGYG000002438_02925;MGYG000004899_01078;MGYG000000243_02417;MGYG000001783_00138;MGYG000001783_00512;MGYG000001925_01678;MGYG000004899_02902;MGYG000001925_00504;MGYG000001925_02673;MGYG000002834_00630;MGYG000002293_00753;MGYG000004797_01501 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.17647058823529413 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.8823529411764706 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.5294117647058824 - 1.0 - 1.0 - 1.0 - 0.7647058823529411 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1799813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1302235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANGVVFVTTK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2323325 0 1367153 0 1048102 0 0 1336197 0 2014095 1005705 1515271 0 0 1855132 887325 0 0 0 2025730 1307484 0 0 0 1414331 1472914 1674708 0 1273993 1572824 0 0 1006852 1556197 1745421 0 1784729 1107935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259701 0 0 0 0 0 0 264594 0 0 0 0 0 0 229696 0 0 0 0 0 271335 0 0 0 291221 473350 214547 0 0 0 0 0 0 0 366985 0 354600 0 867885 0 442550 0 369446 0 0 199420 0 799181 0 357477 0 0 657459 363947 0 0 0 623256 221358 0 0 0 590827 419684 637771 0 1073729 295454 0 0 595250 330882 292386 0 314689 257437 -AANGVVIITTK MGYG000000042_01138;MGYG000002478_01456;MGYG000004876_03105 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4772@1|root,COG4772@2|Bacteria,4PM03@976|Bacteroidetes,2G09Q@200643|Bacteroidia,4AV6D@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1413305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 945134 0 0 0 0 0 0 0 0 0 0 1285124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690791 0 0 0 0 0 0 0 0 0 0 0 0 270445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANGVVLITTK MGYG000002438_02058;MGYG000003697_00063;MGYG000001306_00077;MGYG000002438_00500;MGYG000002478_01456;MGYG000002960_00789;MGYG000002455_02640;MGYG000001780_01166;MGYG000000781_01695;MGYG000004876_02091;MGYG000003697_02396;MGYG000004797_02570;MGYG000001346_03464;MGYG000004899_00028;MGYG000000243_03191;MGYG000000196_00609;MGYG000002834_00176;MGYG000002478_02188;MGYG000004876_01524;MGYG000001643_02196;MGYG000001835_01972;MGYG000002171_01681;MGYG000004876_03105;MGYG000001643_01263 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.20833333333333334 976|Bacteroidetes 1.0 P 0.9166666666666666 TonB-linked outer membrane protein, SusC RagA family 0.7083333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 0.9166666666666666 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 157811 0 175452 0 0 270172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208837 179626 0 0 0 195150 0 154113 0 106451 0 219859 148659 0 0 0 264227 214224 635967 0 704421 0 0 323381 0 546535 0 0 447189 0 0 0 0 545169 0 0 0 0 1094027 589702 1924133 337171 0 143570 0 0 0 448806 0 435250 459106 0 0 0 710640 502753 654127 0 778106 0 0 981208 0 181887 0 0 906478 0 0 0 0 0 0 0 0 0 868661 0 0 822434 0 713114 0 532522 0 0 0 175487 499795 0 0 0 753220 0 0 0 1494894 0 0 666210 0 0 0 0 923577 0 0 0 0 0 0 612827 0 0 333695 960632 738318 870328 0 420670 0 0 0 0 0 502819 1057242 0 0 0 0 1090157 154672 0 708272 0 0 410199 0 438279 0 0 0 0 0 0 0 407259 0 2260507 0 0 0 412627 2235725 0 0 256493 0 3080153 0 927616 0 397291 0 0 0 0 172409 257927 -AANGVVMITTK MGYG000002478_01935;MGYG000000781_01691 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2017165 0 0 2116268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361698 0 334915 0 0 449207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328726 0 -AANIAANK MGYG000000003_01531 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANIIGIQIEFAK MGYG000002506_02942;MGYG000002494_02450;MGYG000002515_03184;MGYG000002323_00405;MGYG000002366_00455;MGYG000002534_00411;MGYG000002535_04680;MGYG000002477_00168 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,3XPK7@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 793675 799249 873704 765884 546869 818637 1057538 1232530 991615 937828 484117 784398 248730 896947 655584 229911 744715 0 655273 761017 719535 1080823 0 1093084 754985 841470 883162 0 1022030 1232874 825201 989511 807812 848600 1183339 940639 952468 634915 1584045 1378223 1442731 1364097 1475734 3240894 2052083 1872040 1755313 2080486 871941 1904523 859732 1608294 2140047 1597567 2592118 0 1570927 1579209 2053455 4638962 0 2876382 1958839 1833104 1686323 0 2317325 1629706 945244 1799065 1300430 1576862 1704992 1557852 1563675 1418126 884677 822717 614358 348017 1125869 2151019 1128996 1239256 560847 1110688 850202 1056945 835578 1028911 805289 1198677 950627 0 872353 962750 1129057 1460703 0 2423565 1059966 763525 869933 0 816741 795628 1039713 811313 908765 1034379 1013661 791623 629189 957054 855035 673761 776135 612533 510947 896649 1075957 920238 568852 922872 430746 749994 558522 525573 594627 520989 618429 0 777455 539336 922256 707993 0 710941 754363 748926 908552 0 401921 621953 280542 610366 525602 1018027 1071680 781597 665446 287661 0 3992206 0 3252006 2851990 4521526 2127515 0 2734864 0 28041241 0 5311486 0 0 2170623 0 0 1937778 5747747 0 1288431 0 0 2040290 3921906 1809540 0 16513 2240381 0 0 2480973 3400071 0 15522 5473473 0 -AANIIVKDEK MGYG000003372_00011;MGYG000002477_01208;MGYG000002535_03830;MGYG000002515_04070;MGYG000002494_02687;MGYG000002323_03813;MGYG000002506_03877 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3029@1|root,COG3029@2|Bacteria,1RD34@1224|Proteobacteria,1S419@1236|Gammaproteobacteria,3XPS9@561|Escherichia 0.5714285714285714 1236|Gammaproteobacteria 1.0 C 1.0 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane 1.0 frdC 1.0 GO:0000104,GO:0001539,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006996,GO:0008150,GO:0008152,GO:0008177,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016635,GO:0022607,GO:0030030,GO:0030031,GO:0032991,GO:0040011,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048870,GO:0051179,GO:0051674,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071973,GO:0097588,GO:0098796,GO:0098797,GO:0098803 1.0 - 1.0 ko:K00246 1.0 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 1.0 M00009,M00011,M00150,M00173 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002 1.0 - 1.0 - 1.0 iYL1228.KPN_04551 1.0 Fumarate_red_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 898975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1076476 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1798119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423919 0 0 0 992591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANIMLDAGAK MGYG000001378_00980 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EF 1.0 COG0462 Phosphoribosylpyrophosphate synthetase 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 2144811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANIMLEAGAK MGYG000001346_00360;MGYG000002549_01851;MGYG000004876_02520 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EF 1.0 COG0462 Phosphoribosylpyrophosphate synthetase 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 236619 0 0 0 0 0 690770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 543250 0 690099 0 0 995421 0 0 777930 0 0 0 0 0 0 0 471448 0 1960374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308781 0 592103 0 0 0 0 0 664496 0 0 0 0 0 0 0 355650 0 758774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517548 0 373710 0 0 565282 0 0 306262 0 0 0 0 0 0 0 338596 0 430549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247203 0 179206 0 0 1394154 0 0 14726981 0 0 0 0 0 0 0 152527 0 519439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANIMMEAGAK MGYG000002281_04553;MGYG000000196_02130 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EF 1.0 COG0462 Phosphoribosylpyrophosphate synthetase 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 296015 663483 0 265114 0 0 0 0 0 0 0 419580 0 0 0 0 0 0 0 323639 0 341945 0 0 0 0 0 0 0 0 0 0 0 0 0 174939 0 0 551770 620696 493911 486844 0 563783 0 0 0 0 0 712292 0 0 0 0 0 0 0 499119 0 287986 0 0 0 0 0 0 0 0 222595 0 0 0 0 464434 0 0 576298 534761 607206 562440 0 423390 0 0 0 0 0 754336 0 0 0 0 0 0 0 322080 0 565046 0 0 0 0 0 0 0 0 329380 0 0 0 0 433997 0 0 355937 0 174431 0 0 0 0 0 0 0 0 568226 0 0 0 0 0 0 0 0 0 301594 0 0 0 0 0 0 0 0 0 0 0 0 0 480448 0 0 0 298927 0 259035 0 330479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANINK MGYG000001564_01347 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster clostridioformis_A|m__MGYG000001564 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2104130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANKFPAIIYGGA(Ala->Lys) MGYG000002494_03782 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 L 1.0 Type III restriction protein res subunit 1.0 yejH 1.0 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 1.0 - 1.0 ko:K19789 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03400 1.0 - 1.0 - 1.0 - 1.0 Helicase_C,ResIII 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANKFPAIIYGGAEAPI MGYG000002494_03782;MGYG000003372_02072 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 L 1.0 Type III restriction protein res subunit 1.0 yejH 1.0 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 1.0 - 1.0 ko:K19789 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03400 1.0 - 1.0 - 1.0 - 1.0 Helicase_C,ResIII 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANKFPAIIYGGK MGYG000002323_02760;MGYG000002506_01672 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance 1.0 rplY 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02897 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L25p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 279210 0 246284 352832 178860 463482 466793 222726 0 378436 75155 252866 161968 170916 347689 84534 208823 0 224567 194108 436865 530723 0 829326 0 314093 375766 0 453509 381142 184137 0 337386 212372 476583 344917 274439 251807 418596 0 465864 396563 405551 623871 301516 514900 0 665732 408818 431635 139980 496199 513451 414650 403766 0 514673 482638 525645 831700 0 694076 0 482022 443946 0 0 538715 364650 0 356906 411123 577577 446857 553840 559375 367612 0 617839 111652 745649 1133629 461454 440538 0 356895 526356 652756 361337 574543 361815 713350 392440 0 317335 483479 714436 973657 0 1310672 0 71226 310644 0 618860 533778 389619 0 474137 447982 354901 461217 105084 611335 0 0 0 0 0 0 0 86786 0 0 0 0 0 0 0 0 0 0 0 76230 330720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84455 91936 60484 0 0 0 0 0 0 148991 0 0 164752 122403 0 102746 0 0 0 0 0 0 166636 0 0 0 0 0 0 57376 0 0 0 75621 0 -AANKGEDDKVSTALAR MGYG000000198_01214 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,21YVN@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 elongation factor G 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 751965 0 0 0 0 0 224009 0 344516 0 0 0 0 523726 0 0 0 0 0 0 0 0 0 0 0 388490 0 0 466722 0 0 0 0 0 637238 0 385985 0 229579 0 0 0 0 0 174225 0 0 0 0 0 0 292053 0 0 0 0 0 0 0 0 0 0 0 101803 0 0 233304 0 0 0 0 0 373858 0 319738 0 1071340 0 0 0 0 0 786187 0 820778 0 0 0 0 875201 0 0 0 0 0 0 0 0 0 0 0 311996 0 0 932167 0 0 0 0 0 455127 0 286752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238247 0 0 0 0 0 420978 0 318971 0 0 0 0 559641 0 0 0 0 0 0 0 0 0 0 0 500732 0 0 38252 0 0 0 0 0 0 0 222021 0 -AANKPDAIKEK MGYG000003937_00036 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 550289 690688 0 0 0 0 0 0 0 723643 990503 0 834801 0 0 903309 999833 1617993 0 1079947 780196 0 0 0 756333 556000 0 1280746 694961 0 0 0 0 0 621991 0 684420 0 0 0 0 0 0 0 0 0 0 0 0 0 39082 0 0 0 0 0 0 56578 32247 0 0 0 0 0 0 0 34256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41569 0 0 58187 0 0 0 0 0 0 55967 0 0 0 0 145598 0 0 0 0 0 0 0 0 0 0 154587 191374 0 0 0 0 0 0 0 132925 183865 0 259261 0 0 332858 158702 345894 0 196650 0 0 93147 0 117454 125409 0 572341 105445 0 0 0 0 0 106840 0 153003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 33334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANKYAGTQTEK MGYG000000212_01587;MGYG000000251_01537;MGYG000000154_01425;MGYG000000193_03705;MGYG000000067_02301;MGYG000001319_01032 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1592@1|root,COG1853@1|root,COG1592@2|Bacteria,COG1853@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF2201_N,Fer4_6,Flavin_Reduct,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 819592 0 0 0 0 0 0 1098628 0 0 0 0 888571 0 0 0 0 513247 0 424122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 266889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157635 0 0 0 0 0 0 0 0 0 222823 0 44003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANKYAGTQTEKNLQEAFAGESQAR MGYG000000212_01587;MGYG000000251_01537;MGYG000001319_01032 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1592@1|root,COG1853@1|root,COG1592@2|Bacteria,COG1853@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF2201_N,Fer4_6,Flavin_Reduct,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANLDAIHDTVHE(Dioxidation)MAR MGYG000000123_00688;MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000002278_00133;MGYG000000139_02333;MGYG000000274_00102;MGYG000000249_00436;MGYG000000245_00992;MGYG000002702_00869;MGYG000004785_01880;MGYG000000076_00982;MGYG000002517_02838;MGYG000001560_01146;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000004263_01270;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000002837_00277;MGYG000000208_01702;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000000909_00619;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000004697_00836;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.45 186801|Clostridia 0.975 C 1.0 Rubrerythrin 0.6 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.975 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 944356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 819340 818595 0 0 0 1150059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290131 0 0 -AANLDAIHDTVHEM(Dioxidation)AR MGYG000000123_00688;MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000002278_00133;MGYG000000139_02333;MGYG000000274_00102;MGYG000000249_00436;MGYG000000245_00992;MGYG000002702_00869;MGYG000004785_01880;MGYG000000076_00982;MGYG000002517_02838;MGYG000001560_01146;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000004263_01270;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000002837_00277;MGYG000000208_01702;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000000909_00619;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000004697_00836;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.45 186801|Clostridia 0.975 C 1.0 Rubrerythrin 0.6 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.975 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 462968 821616 0 467389 0 1052010 335847 746699 166542 0 0 0 0 0 0 0 0 0 0 0 0 1098524 0 490207 0 278489 0 0 0 0 0 0 0 703262 0 0 424599 0 872682 1302497 0 631766 0 447784 545033 562342 796021 0 0 0 0 0 0 0 0 0 0 0 0 241270 0 696640 0 680106 0 0 0 0 0 0 0 714650 0 0 641336 0 290934 790347 0 335142 0 371162 467999 484540 268417 0 0 0 0 0 0 0 0 0 0 0 0 891434 0 322845 0 256418 0 0 0 0 0 0 0 511191 0 0 463083 0 605520 685775 0 336532 0 0 597783 872825 430830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 370408 0 0 0 0 0 0 0 225113 0 0 257976 0 904878 763136 0 626188 0 774229 1264059 693504 935706 0 0 0 0 0 0 0 0 0 0 0 0 719389 0 701060 0 639142 0 0 0 0 0 0 0 1009555 0 0 170251 0 -AANLDAIHDTVHEM(Dioxidation)ARDEAR MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000000139_02333;MGYG000000249_00436;MGYG000000245_00992;MGYG000000076_00982;MGYG000002517_02838;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.4482758620689655 186801|Clostridia 0.9655172413793104 C 1.0 Rubrerythrin 0.6551724137931034 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.9655172413793104 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANLDAIHDTVHEM(Oxidation)AR MGYG000000123_00688;MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000002278_00133;MGYG000000139_02333;MGYG000000274_00102;MGYG000000249_00436;MGYG000000245_00992;MGYG000002702_00869;MGYG000004785_01880;MGYG000000076_00982;MGYG000002517_02838;MGYG000001560_01146;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000004263_01270;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000002837_00277;MGYG000000208_01702;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000000909_00619;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000004697_00836;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.45 186801|Clostridia 0.975 C 1.0 Rubrerythrin 0.6 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.975 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2237682 2700922 1461812 1526979 2236209 2216673 1198192 1782990 1704138 2245814 1952980 1920704 2368711 1674902 2556426 2551169 2298923 5258386 1783623 2220370 1930557 3085885 2459673 1385407 1939182 1692592 1824631 2670385 2531337 2010120 1303944 1712938 1512123 1746811 1750031 1357355 1652177 1871627 2584562 4038136 1476761 1859936 1460326 1455241 1714703 2258954 2532743 1419352 1211232 1298599 1331215 1211150 1718787 1031089 2119686 5752538 1364230 1856487 1738177 930856 2943905 2259320 1206638 1458472 1488891 3399461 1951291 1129308 3720513 1692128 1235572 1894149 2551002 2117723 1923461 1603779 2419812 3916793 1190655 1498028 912135 1719479 1573528 2311610 1946504 1825933 1542945 1900496 1852727 1937457 2596081 2358652 1534747 1856445 2044436 1913546 2302954 3308556 3100753 1621249 1696886 2111200 2423041 3121473 2534337 2148652 1337692 2760559 1773616 1997246 1560822 1758427 1661956 1549091 1754035 2451735 1419803 1431806 1513180 1121295 1310231 1287581 1466158 1174600 1086053 1325565 1699169 1363025 1166521 1524338 1686680 1763520 1187659 2002707 1421887 1637953 820805 1381115 1259576 1639615 1453839 1033196 1311897 1416904 1736429 1734254 1662669 1004840 1401243 1664186 1180719 1716454 3997452 3529630 3404523 4560160 1274319 2340675 6103483 4152176 3225333 4386748 3453372 3225899 2129179 5337632 4460825 3547101 3573979 1355103 4355054 2212196 4764362 3236488 2880825 2994289 3898660 3390202 4144377 4485445 5776414 1890868 3270868 4055067 4189149 4331023 3724397 4360782 2489699 2626891 -AANLDAIHDTVHEM(Oxidation)ARDEAR MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000000139_02333;MGYG000000249_00436;MGYG000000245_00992;MGYG000000076_00982;MGYG000002517_02838;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.4482758620689655 186801|Clostridia 0.9655172413793104 C 1.0 Rubrerythrin 0.6551724137931034 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.9655172413793104 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1917888 3301756 2768635 1328549 2667240 2226337 1351871 2540929 462494 3042302 2082315 619963 2541757 1867528 2414963 1989920 2476600 3156142 0 1876455 2005545 2866776 412557 427136 2865661 1706003 401531 2119148 1905538 546053 348245 2640124 1756426 1446360 1608293 1156151 410129 1814359 256255 584128 0 212133 309527 423057 267875 338787 227981 291463 252976 0 351144 311025 253050 254499 151414 0 238118 189579 249311 291321 682400 252835 354340 279504 324426 746792 387595 105052 727375 380005 297949 558235 744507 98270 413386 304479 3562586 3431061 2205642 1600682 1053558 1719985 1938428 2266622 1665805 2158406 2273708 1445132 1750233 2638158 2745267 2600552 2493781 430266 3755284 2325790 1623819 2696557 1752809 1629154 3261840 2182525 2775688 1556441 2023388 3124142 1738463 2469914 3500323 2541965 1814478 1333314 2212276 1903943 770606 978975 1223761 1050656 896625 1031407 809029 989674 862723 1122637 617183 588291 969845 616444 824982 994957 977767 460104 843573 1408499 1499585 882596 998221 814078 1058427 945811 797887 1201720 1321309 697062 762551 734213 676387 555023 525621 1451723 937004 1423167 847181 1866234 2037725 2647384 928979 1406142 2000491 1769878 707140 2093884 1606773 1615484 1223782 1848542 1395724 911817 2663870 0 1454163 1335844 1887154 939874 441413 337872 1213935 1129713 1223350 1516018 1541723 762993 1747972 2324687 2680236 1169971 946442 1595570 645846 938117 -AANLDAIHDTVHEMAKDEAR MGYG000000359_01014 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7182|s__|m__MGYG000000359 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 274829 0 0 0 0 0 0 0 0 0 0 302933 0 211556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209218 0 0 0 0 0 0 0 0 0 0 208670 0 1052548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1232921 0 0 0 0 0 0 0 0 0 0 666912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151805 0 0 0 0 0 0 0 0 0 0 0 0 -AANLDAIHDTVHEMAR MGYG000000123_00688;MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000002278_00133;MGYG000000139_02333;MGYG000000274_00102;MGYG000000249_00436;MGYG000000245_00992;MGYG000002702_00869;MGYG000004785_01880;MGYG000000076_00982;MGYG000002517_02838;MGYG000001560_01146;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000004263_01270;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000002837_00277;MGYG000000208_01702;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000000909_00619;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000004697_00836;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.45 186801|Clostridia 0.975 C 1.0 Rubrerythrin 0.6 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.975 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 5576112 5694172 3659892 3963177 4709512 5450761 3365725 4220654 3711099 4179236 4855220 4558187 4290140 3806742 5333016 4542061 4438495 8926898 3081023 4843847 5811381 6021736 7885800 4040208 4144401 3804367 5092821 7100210 5517388 4851193 3416108 5017498 3342489 4094392 4716991 4587595 4159158 4310643 2810255 6207714 1974453 2171990 2173549 1924602 2222817 2398005 1725698 2192543 1749593 1619897 1698288 1617553 2634028 1816602 2957713 8490225 1711247 1887218 2673440 1755525 4632646 3025456 1675522 1973091 2537131 5405461 2505763 2174118 4068749 2814319 1847467 2480493 2798343 2873008 1796524 2277610 5201348 4852097 3421808 3265929 2386241 3721506 4705657 4258151 3195097 4920034 2729279 5151946 3038298 4955196 6647112 3677902 4250026 4841309 5114291 4763665 4852600 5741163 7958430 3386139 4762996 5317570 5242488 9597818 5699569 5290128 3995157 5433730 4011455 5321019 5864103 4390789 5290704 3678137 1635816 3339344 1423788 1670609 2514968 1646064 1773751 1714583 1716350 1406590 1761593 1877055 2165121 2068665 1214813 1742685 2448519 4371979 1492658 2142194 2152599 1913017 3736275 2076638 1826200 1641382 1894049 3997549 2406970 1773992 2944217 2458348 2041651 1114686 1625181 1788749 1431103 2264990 11532554 11356787 6433684 14463179 3449369 5655705 12421202 7921468 6663209 10943945 8496174 8560975 4674063 10847524 9295816 8073110 9209342 4287495 11395956 6004974 12133821 7790208 7477667 8979955 7556161 6817444 9600519 10073127 16431483 4233275 7746341 11185839 9377196 10096575 6488277 7853954 5234601 5944520 -AANLDAIHDTVHEMARDEAR MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000000139_02333;MGYG000000249_00436;MGYG000000245_00992;MGYG000000076_00982;MGYG000002517_02838;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.4482758620689655 186801|Clostridia 0.9655172413793104 C 1.0 Rubrerythrin 0.6551724137931034 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.9655172413793104 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1672022 2010937 3208173 1077303 2377429 2095355 924637 1901539 1290213 2347209 2302086 1792477 2260321 1944996 1546849 1328531 1461740 2188860 1561179 1275445 1454031 2295973 2662187 1019598 1645979 1239144 1206442 3274705 1567632 2081730 1774966 2363103 1655053 1139976 1769998 1039943 1069413 1796550 150919 297697 0 0 470371 181772 0 203361 0 276785 257732 0 194354 0 206095 209885 0 214886 0 96854 116277 219584 0 347327 0 0 67527 118345 412212 0 526826 329794 173267 147405 152005 0 56660 0 1913489 2533592 1706992 1299101 1073181 1549237 1451054 2075188 1018869 0 1214922 1807327 1642064 1535599 1818105 1864983 1665547 716577 1950778 2139351 1456733 1771831 1463533 1478646 2061664 2582701 1931238 1863449 1628016 2285568 1495880 1991384 1649252 2134332 2006717 1135639 1788526 1156323 113475 673143 408809 422528 582966 316733 265889 80689 69934 251147 335263 0 47782 86940 316421 90256 0 332178 54967 153878 846428 517031 1202658 284255 140927 0 259940 1465683 503517 0 370558 76822 234058 315156 268225 708673 52108 585213 729351 1777410 2382162 4271647 722602 1317513 1162387 926326 810128 2165245 2699518 1529727 1728243 1451682 1481541 581032 2512153 0 1223678 673794 1373239 414343 0 725127 636929 672643 1004595 127101 1658187 826731 1783822 3473131 2250190 729515 561867 1324490 773399 1253356 -AANLDPEFVK MGYG000001415_00933 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG1390@1|root,COG1390@2|Bacteria,4NTEY@976|Bacteroidetes,2G2KK@200643|Bacteroidia,22UJC@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane 1.0 - 1.0 - 1.0 - 1.0 ko:K02121 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 ATP-synt_B,vATP-synt_E 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1060019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175754 0 0 0 0 0 0 0 0 0 -AANLER MGYG000000121_01611 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Eubacteriales|f__Eubacteriaceae|g__Eubacterium|s__Eubacterium callanderi|m__MGYG000000121 1.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25V9A@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 S 1.0 Endoribonuclease that initiates mRNA decay 1.0 rny 1.0 - 1.0 - 1.0 ko:K18682 1.0 ko03018,map03018 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03019 1.0 - 1.0 - 1.0 - 1.0 DUF3552,HD,KH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANLMLENGAK MGYG000002438_00755 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,22WNU@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Purine metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1104847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1120414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANLPEAMIENIAK MGYG000003693_02548 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 487692 0 0 0 0 383914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3441730 0 0 0 0 5345514 0 0 0 0 3903795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANLPEQMIQNIAK MGYG000001489_01081;MGYG000000105_01496 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,22W7D@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1914386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1147837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANLPQAMIEN(Deamidated)IAK MGYG000001783_00059;MGYG000000273_00241;MGYG000001306_01209 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328617 0 0 0 0 0 0 0 0 0 0 772592 0 0 1584150 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 665918 0 0 0 0 0 0 0 0 0 0 0 0 0 150117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANLPQAMIENIAK MGYG000001783_00059;MGYG000000273_00241;MGYG000001306_01209 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877205 0 1202117 0 0 0 0 0 1967903 0 0 0 0 0 0 3542563 0 0 0 0 5024315 0 0 0 0 4012587 0 0 0 0 799949 0 0 0 0 563352 0 0 668489 0 432013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANLPQQM(Oxidation)IENIAK MGYG000004797_01413;MGYG000003521_01644;MGYG000002438_01052;MGYG000002478_01739 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 877009 982862 0 0 0 0 0 0 1891578 0 0 1744180 2074666 0 0 0 838322 604748 0 789938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 714727 311878 0 0 0 0 0 0 731362 0 0 452700 300619 0 0 0 243099 399038 0 383824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 854689 829641 0 0 0 0 0 0 655311 0 0 813691 692869 0 0 0 335288 760121 0 610949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278875 397189 0 0 0 0 0 0 512628 0 0 392941 281491 0 0 0 372311 324597 0 255472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1263092 1272379 0 0 0 0 0 0 1690414 0 0 734048 970574 0 0 0 665393 646108 0 1084801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANLPQQMIENIAK MGYG000004797_01413;MGYG000003521_01644;MGYG000002438_01052;MGYG000002478_01739 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 4542577 4677374 5177608 4468329 6079889 3912216 6285145 3731370 5181481 4236023 3782936 5277330 11042101 3924997 3083058 7699305 4834839 3341391 3786636 4349924 4857148 3532293 4939537 5351580 3638768 4979459 5504437 5857090 5504319 5143391 7547620 5260981 4454925 2713352 4481623 6591185 4687451 4790455 5475843 4341660 4544695 5697744 10706211 5474240 5259924 6125779 3835553 6733666 7005638 6994791 21455142 6200246 7127953 13415177 6331660 4423669 6634071 6889203 8825596 6766957 6865475 5122109 5495079 6401016 7542925 6049588 6655989 6767909 4230425 6760319 5305137 3812915 4675481 4652729 4943724 3846700 2014606 2466655 3055155 1897439 4525779 3363310 3069432 2157468 2746741 0 2920942 3559311 4786265 2326222 1670510 4541417 2251452 4964304 1985405 1931556 2998283 2878303 4194129 3563204 1725489 2176421 1735441 3919143 3050887 2588713 3176780 2789842 2147707 1070273 2020510 2986793 2112991 2499442 1687772 1366825 1385095 1102436 1339227 1154926 0 1435752 1243474 1506967 1131957 1696860 1802690 1691878 1389721 1430617 1048019 348932 1315987 1254111 4009971 0 599185 792893 1703240 1821404 1460587 259762 980774 1784513 1067157 1625671 1168990 1614679 1869434 1903288 1580731 864292 5514947 4433873 4499385 6886509 13145385 7127387 5791122 7313573 7135853 4537727 5975938 7867703 16806912 5504562 4611345 11113439 7443014 10906551 5905034 8627025 8162660 7047378 11157281 6095634 6338937 7501137 5479027 11642177 7072663 11799936 5765439 8355174 4653101 7945623 8609911 6245279 9352517 6595706 -AANLTDF MGYG000002517_02338 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 1.0 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism;Carbon metabolism 1.0 none 1.0 232670 0 0 0 0 91297 78984 50045 0 102413 0 0 0 113639 352839 0 377091 0 67369 56610 0 197144 0 0 121766 0 182478 0 0 0 0 0 0 0 72454 98038 125952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492479 0 0 382026 0 122440 129279 475014 268445 352717 490979 313415 0 285297 479499 339068 283271 0 552278 515639 0 182421 0 141478 593187 110565 530631 0 0 449564 0 0 0 0 462972 430933 540735 0 3876593 0 0 3834134 0 1625177 1845730 3703422 5147638 2390021 1708559 2069623 0 6875567 4669897 1787853 3539860 0 3925596 5108582 0 474063 0 576759 2878593 2396978 3924294 0 0 4859005 0 0 0 0 3880013 2734491 4931441 0 2034367 0 0 0 0 2234599 3121855 2061183 2366788 4047217 207632 3254043 0 141347 4335260 2322509 3543340 0 3330928 1132493 0 595200 0 91863 74030 1397409 159770 0 0 1088947 0 0 0 0 0 100920 435897 0 -AANLVGEEGR MGYG000002528_00945 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,26AUV@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1763733 0 0 0 0 0 0 0 0 0 2179269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1722214 0 0 0 0 1809565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433308 0 0 0 0 0 0 0 0 0 288401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANLVK MGYG000001714_01819 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus_A|s__Coprococcus_A catus|m__MGYG000001714 1.0 COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 UPF0210 protein 1.0 - 1.0 - 1.0 - 1.0 ko:K09157 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF711 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9352536 0 -AANNDEKC(Carbamidomethyl)IGVITWMHTFSPAK MGYG000001313_02667;MGYG000001750_01414;MGYG000002478_02453 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,2FMIU@200643|Bacteroidia,4APG1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the conversion of L-arabinose to L-ribulose 1.0 araA 1.0 - 1.0 5.3.1.4 1.0 ko:K01804 1.0 ko00040,ko01100,map00040,map01100 1.0 - 1.0 R01761 1.0 RC00516 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Arabinose_Iso_C,Arabinose_Isome 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-arabinose isomerase. L-arabinose ketol-isomerase. Requires a divalent metal ion (the enzyme from the bacterium Escherichia coli prefers Mn(2+)).-!-The enzyme binds beta-L-arabinopyranose and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene-diol mechanism.-!-The enzyme can also convert alpha-D-galactose to D-tagatose with lower efficiency. beta-L-arabinopyranose = L-ribulose. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 760227 0 0 0 0 548551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2711107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1199746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 630319 0 0 0 0 0 0 0 0 0 0 -AANPTAEKPFVLGLPTGSSPLGMYK MGYG000002438_00973 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,22W1C@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6850205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14766844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANPTPEKPFVLGC(Carbamidomethyl)PTGSSPLGM(Oxidation)YK MGYG000002171_00281;MGYG000002455_02070;MGYG000000196_01768;MGYG000001661_00842;MGYG000003351_04413;MGYG000002549_00225;MGYG000002478_04559;MGYG000002560_02540;MGYG000000243_00067;MGYG000001378_02954;MGYG000004876_00832;MGYG000000013_02920;MGYG000000029_00780 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,4AKMP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1208100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 712038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANPTPEKPFVLGC(Carbamidomethyl)PTGSSPLGMYK MGYG000002171_00281;MGYG000002455_02070;MGYG000000196_01768;MGYG000001661_00842;MGYG000003351_04413;MGYG000002549_00225;MGYG000002478_04559;MGYG000002560_02540;MGYG000000243_00067;MGYG000001378_02954;MGYG000004876_00832;MGYG000000013_02920;MGYG000000029_00780 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,4AKMP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways 1.0 none 1.0 774384 1056090 673299 1461003 341220 704956 1498973 1127721 1057186 779783 722701 847521 576042 455299 263080 751127 844741 166074 425181 553764 1123713 660106 385143 1186596 455854 692009 1304836 636922 1092512 989518 1385253 920265 784715 780101 722707 1182654 966180 471258 2538337 1762855 2441834 3616859 2591646 2638802 2735645 3205240 2458185 4268427 4265079 2720776 2238512 3797441 3691686 2584788 2770513 1193334 2823756 2806250 3641870 2812924 1707895 2543196 2957443 3770103 4028772 1139187 2734600 2987459 1927510 2917670 2255843 2763845 3478691 2836819 3037230 2417360 1131506 1043735 1076477 911984 1249035 1608671 1338301 1189398 857890 859021 1135403 1314949 818660 815524 670711 1034830 1207022 2075043 966473 860616 759518 1013614 1653788 1465271 845045 1060113 955892 1595996 1198561 1145319 1316466 1236121 944551 1108543 1182165 1309381 929593 909221 271021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238489 0 0 0 0 1018114 521042 785241 1277783 1388950 2101397 1448360 1537540 1686565 1023511 1517242 883682 1859664 487693 876892 1534335 1125043 1640073 929365 2089426 1294064 1336956 1629741 2339418 1361024 1441487 1055494 1654112 918658 2177028 1088434 962104 715978 1972019 1793836 1313465 1879117 750095 -AANQAGGITTK MGYG000002298_00339;MGYG000004733_00979;MGYG000000212_03058 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3Y0BX@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit 1.0 rplX 1.0 - 1.0 - 1.0 ko:K02895 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KOW,ribosomal_L24 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 2605646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3053091 0 1158511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1061832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2204213 0 819923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANQILTDGVADLILLGNPDEIMSLAK MGYG000000243_02864 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0280@1|root,COG0280@2|Bacteria,4NGX5@976|Bacteroidetes,2FMKY@200643|Bacteroidia,4AK60@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625,ko:K13788 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Methane metabolism;Carbon metabolism;Taurine and hypotaurine metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 2304167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2292764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3600654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANQQGGIITK MGYG000001338_02796;MGYG000000200_01102 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3Y0BX@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit 1.0 rplX 1.0 - 1.0 - 1.0 ko:K02895 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KOW,ribosomal_L24 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 3012966 1992021 0 4793586 0 0 0 0 0 2748463 0 2374350 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1211158 3571928 1080709 0 0 0 0 1796065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382589 0 0 0 0 0 0 0 2064453 363503 0 0 0 0 0 0 0 0 0 576276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618982 1668339 314504 0 0 0 0 0 0 6395297 1891304 0 4091769 0 0 0 0 0 1985679 0 1983337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6178742 4923176 2359857 0 0 0 0 2064911 0 619856 0 0 0 0 0 0 0 0 615255 0 839556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANQQGGIVSQEAPIDASN(Deamidated)VNLVC(Carbamidomethyl)PEC(Carbamidomethyl)GK MGYG000003122_00592;MGYG000003266_00871;MGYG000001636_00357;MGYG000002050_01545 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CVUJ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome 1.0 rplN 1.0 - 1.0 - 1.0 ko:K02874 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L14 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 647119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANQQGGIVSQEAPIDASNVNLVC(Carbamidomethyl)PEC(Carbamidomethyl)GK MGYG000003122_00592;MGYG000003266_00871;MGYG000001636_00357;MGYG000002050_01545 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CVUJ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome 1.0 rplN 1.0 - 1.0 - 1.0 ko:K02874 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L14 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1043421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANSEYQTR MGYG000003693_01542 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0251@1|root,COG0251@2|Bacteria,4NEVA@976|Bacteroidetes,2FN38@200643|Bacteroidia,4AKJZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 endoribonuclease L-PSP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DAHP_synth_1,Ribonuc_L-PSP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165552 0 0 0 0 615044 0 0 0 0 680694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442122 0 0 0 0 215306 0 0 0 0 133668 0 0 0 0 0 0 0 0 0 0 -AANSFGSVK MGYG000002218_00670;MGYG000000138_03130;MGYG000000044_02742 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG3063@1|root,COG3063@2|Bacteria,4PKG6@976|Bacteroidetes,2G3G2@200643|Bacteroidia,2322F@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 NU 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 1406553 1360405 0 0 1399867 2483983 1998431 0 1734055 0 2153224 0 1646439 1404939 0 0 2437916 0 0 2209113 1715115 2566947 0 1600830 2044931 0 2288668 0 1991943 1935442 2819911 1616312 0 1852423 0 1933799 1353133 266231 588447 972798 0 0 1067419 692192 255981 0 362393 0 265557 0 514867 231744 0 0 279913 0 0 396244 828424 0 694561 195705 689341 0 404747 0 766305 498774 307235 414319 0 340572 0 432038 0 1095588 1195452 1296078 0 0 1516647 1707222 1577998 0 1564782 0 1055043 0 1351825 1172269 0 0 1560972 0 0 1670272 1409489 1251525 1635281 805937 874756 0 1189727 0 1353807 1858011 1597233 1110721 0 1516626 0 1412223 1340040 1593783 1705059 1682104 0 0 1512058 2287403 2228972 0 2163507 0 1998008 0 1777046 1862497 0 0 1621073 0 0 1755692 1322193 1072758 1422812 1557911 1648543 0 1781089 0 1854916 2128731 2257305 1443846 0 1606400 0 1906902 822974 782305 808911 720465 0 0 771365 1453684 0 0 536339 0 0 0 922620 185498 0 0 2597110 0 0 0 750442 2126046 553544 788615 0 0 1710547 0 0 108428 1112845 472408 0 688234 0 169640 643086 -AANSYVK MGYG000002438_00958 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0446@1|root,COG0446@2|Bacteria,4NE3A@976|Bacteroidetes,2FRH5@200643|Bacteroidia,22WU3@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6153680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2073279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANTDLAGALQGK MGYG000002549_04077;MGYG000000196_02346 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AWFC@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2727287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1229781 0 0 0 0 140449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2973108 0 0 0 0 297409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANTISPVA(Ala->Thr)ALQGK MGYG000002614_01265;MGYG000002478_00657;MGYG000002560_00458;MGYG000000236_01278;MGYG000001337_02403 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKGC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02014 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1735348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1799416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANTISPVAALQGK MGYG000002614_01265;MGYG000002478_00657;MGYG000002560_00458;MGYG000000236_01278;MGYG000001337_02403 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKGC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02014 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 2674823 3532488 4123556 3267952 4666915 2121237 2964416 2669740 2621173 2729479 4989970 2951312 2189002 4927344 3719720 1427962 2690343 3012357 3210458 2659290 2263957 3938330 2473972 2998178 3495996 2118816 3312395 2894166 3721520 3480634 3092425 1148811 3195835 3801723 3104327 2735847 2421117 2040041 2373379 2908093 3697324 2317445 2040690 2501649 2945910 2289833 2873741 2403669 4440222 2885544 2618028 4864320 1896632 1326879 2492090 2684667 2458190 2511889 1901257 1781494 2507201 2440840 2538791 1560718 2579699 2491298 1862048 2854365 2546533 2195846 2644347 2364832 2566712 2353314 0 0 0 195070 0 281412 0 0 0 0 240352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 624668 0 0 345713 0 0 230449 428555 286111 228282 277063 279204 369849 403501 530313 0 0 0 500673 479463 354423 0 0 0 475600 575072 390902 0 0 192798 0 186476 0 0 565441 670811 646647 0 1214141 830005 1093121 1340411 1598166 1243185 1959787 2428746 2690332 1083051 825749 480905 2176960 1086066 1585705 1601726 2181912 4566027 1470445 2799175 1093060 861763 3935111 1129548 2055215 1965040 1687364 3541269 1936227 1920897 1273541 960061 499759 3020588 2596417 1758063 2113701 1048764 -AANTISPVTALQGK MGYG000002478_00647 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKGC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02014 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 391284 263924 245442 411072 363169 378420 388368 0 380867 288367 321359 351988 616906 256278 0 552870 430723 377569 421003 0 327000 365107 240458 476079 0 319491 345925 138323 318072 404132 377256 320357 321090 0 416320 280188 405766 258306 1567500 1341009 1547701 1603385 1654335 1326530 1134859 1276861 1436455 1325129 1401575 1268548 1470673 1507780 0 1691687 1338691 787215 1637515 0 1348096 1722988 1171774 1300262 0 1366962 1378903 1046633 1564180 1323112 1166160 1345674 1516108 0 1315919 1509661 1511347 1286292 1715262 1406751 0 1395519 2948338 2042796 1955003 1297502 2101289 1568473 1509407 1961966 0 1653601 0 2075443 1096349 2831723 1841770 0 1294213 1507523 0 1844460 0 1539425 1737722 2013635 0 0 2178463 1624982 1388595 0 1837562 1901020 2111309 0 0 0 841436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 894085 0 0 224473 0 678201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 415026 0 0 0 0 0 0 0 0 0 0 645704 0 -AANTNLLK MGYG000002171_00304 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002493165|m__MGYG000002171 1.0 COG0702@1|root,COG0702@2|Bacteria,4NEPE@976|Bacteroidetes,2FMBU@200643|Bacteroidia,4ANN0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 3230790 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1679444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1268850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVA(Ala->Val)LVGTEK MGYG000000142_01601;MGYG000000301_01353;MGYG000000212_01002;MGYG000002312_02491;MGYG000003012_02044;MGYG000003822_02069;MGYG000000002_00289;MGYG000003821_00240;MGYG000000171_01279;MGYG000002772_00614;MGYG000000200_00386;MGYG000000263_00751;MGYG000001338_00128;MGYG000004785_00404;MGYG000000031_02918;MGYG000002186_00350;MGYG000000252_02288;MGYG000004733_01675;MGYG000002298_00401;MGYG000000216_00449 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.95 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.95 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4178720 0 0 0 0 0 0 0 0 0 0 2833144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVAEDELADDGASNPHVK MGYG000000133_01138 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3XZ6D@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner 1.0 ychF 1.0 - 1.0 - 1.0 ko:K06942 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 MMR_HSR1,YchF-GTPase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532426 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVALIGYEK MGYG000000198_03138;MGYG000001564_03639 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,2235C@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 CQ 1.0 BMC domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1243499 0 1173047 2965965 1296932 1214243 696212 1395522 2367892 3184767 1599207 0 0 2892915 3179139 0 1119676 0 0 2107061 2322846 1009173 0 704608 1263992 1890341 2070602 0 1797746 2094818 0 0 859203 2226600 0 1828877 1915341 896033 1529691 0 0 2336510 257421 353561 718613 1558923 1925954 2100786 325729 0 0 1934642 1912236 0 647432 0 0 1303600 1031864 307209 0 0 1672328 2254227 2038146 0 1677911 0 0 0 0 1418083 0 1984299 1842108 719141 5923592 0 3635909 3408708 1740599 527168 2464375 4258965 5234416 3797081 2608534 0 0 5575349 5417678 0 1001505 0 0 4624271 4379431 2656637 0 2314743 1492108 4634346 5270137 0 6541265 4113656 0 0 2483199 1899074 0 5236836 3785169 2697979 5027117 0 6431442 4297139 3208381 4726749 4368262 5566955 4570667 6223365 3505898 0 0 5114393 4594649 0 4150161 0 0 3866306 4118177 4106212 0 3759903 0 4396899 4713519 0 4687259 3641828 0 0 4873019 7046290 0 5160953 4244915 4056995 503287 0 842783 326640 360799 387614 640633 274613 519077 387335 772952 0 0 416006 589064 0 350397 0 0 339240 293471 325708 0 666864 332739 391137 617582 0 534088 519569 0 0 1165589 630354 0 246820 545460 1015319 -AANVALVGTEK MGYG000000142_01601;MGYG000000301_01353;MGYG000000212_01002;MGYG000002312_02491;MGYG000003012_02044;MGYG000003822_02069;MGYG000000002_00289;MGYG000003821_00240;MGYG000000171_01279;MGYG000002772_00614;MGYG000000200_00386;MGYG000000263_00751;MGYG000001338_00128;MGYG000004785_00404;MGYG000000031_02918;MGYG000002186_00350;MGYG000000252_02288;MGYG000004733_01675;MGYG000002298_00401;MGYG000000216_00449 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.95 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.95 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 16963546 17549188 18169804 12004261 19976812 24065438 10223383 19393281 12552768 17647225 20907049 16900422 19849105 14358538 19544718 18644135 24394079 22004522 15135266 19455304 25864384 25219942 14685160 13456926 18910085 14269715 13071632 18453848 21867661 19172702 12317999 17169799 14651336 15713174 17303690 10742991 14649119 16900674 21613531 19826110 15015307 14664261 17965957 9169119 15921706 17134996 17708850 10377299 14051654 7578707 9615285 13514238 13382835 7839375 28419646 25223950 11685288 16661186 14466651 8084677 16517031 14938651 12790325 15732358 16950397 19864305 26380059 14911773 20057811 13849808 15530355 19994303 25261102 18804113 18897881 18216029 27093322 29473365 25422290 19280429 18615452 23539563 21874169 27203932 20685894 29442479 19724059 17074345 20501322 22226561 31758254 22230839 32909608 14086438 29024261 23291687 23523285 31874097 20666607 22272233 27304418 25194283 28268944 21851708 23664376 28755806 27630090 26773839 24649386 30655329 25919144 19504480 22990346 22771238 11069524 16954643 12372566 0 14015075 11658390 11212384 11172756 10284349 14964628 10977513 11744445 10827952 12701076 10028551 11252298 23057743 11310238 8479453 11983490 10675881 14557744 0 14553573 9226578 8813752 0 16679566 40169149 13107228 16091670 12150216 13753145 7662992 9617107 10146520 0 14984379 32828023 31592531 36643196 42494714 13258505 37223924 47582306 31633036 26785391 42682515 41801792 32609424 28485979 38435634 30038435 20489136 36176104 8323545 31297938 15793326 41072007 30059166 11843586 28095787 26830054 42546408 32911557 12094919 42666529 17807196 30560586 33686270 49015607 33487415 20727836 45189347 19919529 28342586 -AANVALVGTEK(Delta_H(4)C(6)) MGYG000000142_01601;MGYG000000301_01353;MGYG000000212_01002;MGYG000002312_02491;MGYG000003012_02044;MGYG000003822_02069;MGYG000000002_00289;MGYG000003821_00240;MGYG000000171_01279;MGYG000002772_00614;MGYG000000200_00386;MGYG000000263_00751;MGYG000001338_00128;MGYG000004785_00404;MGYG000000031_02918;MGYG000002186_00350;MGYG000000252_02288;MGYG000004733_01675;MGYG000002298_00401;MGYG000000216_00449 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.95 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.95 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4040894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVIR MGYG000003362_00528 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Dysgonomonadaceae|g__Dysgonomonas|s__Dysgonomonas sp900079735|m__MGYG000003362 1.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,2FM2Z@200643|Bacteroidia,22W21@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate 1.0 purL 1.0 - 1.0 6.3.5.3 1.0 ko:K01952 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04463 1.0 RC00010,RC01160 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C,GATase_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylformylglycinamidine synthase. phosphoribosylformylglycinamidine synthetase. - ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D- ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D- ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVMEIYGSK MGYG000002272_00822;MGYG000001300_00352;MGYG000002040_00733;MGYG000000022_01091;MGYG000003166_01369;MGYG000002545_02252;MGYG000002641_00365;MGYG000003899_00843 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 0.875 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 GABAergic synapse;Necroptosis;Glyoxylate and dicarboxylate metabolism;Nitrogen metabolism;Arginine biosynthesis;Metabolic pathways;Alanine, aspartate and glutamate metabolism;Glutamatergic synapse;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of amino acids 1.0 none 1.0 0 0 1576777 0 506385 1507356 1426750 0 1265543 0 1490472 1106622 1122546 1348180 0 0 1001397 1298988 1752414 1516209 1077985 1892680 1550782 991560 1596511 1655566 0 1565975 0 1107071 0 1192218 1513446 1543775 0 1298936 1416631 6088365 2141052 1715961 1875583 0 1456447 1518102 2887994 0 2061785 0 0 2133195 902946 2678598 0 0 2343003 0 2546018 2845227 1355816 0 0 1751526 2437086 0 0 0 0 0 0 1774644 1877664 1954456 0 2001171 1971621 2121586 412231 837897 632722 0 1101654 956700 777769 0 848343 0 627213 0 906939 694795 0 0 639626 1735436 474435 478133 937695 713514 1883846 1085432 578264 982911 0 2098740 0 953728 0 755142 511295 234831 0 797120 286582 731694 1088069 1016360 1067126 0 1012953 962910 1286746 0 783933 0 612079 1260040 1473320 573595 0 0 1117032 0 1096356 1418244 1153191 1761580 0 0 1026157 872026 0 0 0 1159476 0 1162377 1335509 1094856 0 882377 974624 1057509 433493 479562 539845 0 674811 557887 514940 0 504629 0 309926 491563 0 249533 0 0 269399 0 0 233873 451146 511262 1888790 712318 418885 302662 0 2025600 0 567947 0 576140 503807 406459 0 331097 369017 651934 -AANVN(Asn->Ala)LIGYEK MGYG000004667_05617 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium|s__Clostridium beijerinckii|m__MGYG000004667 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 959679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1934883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5119804 0 0 0 0 0 4984440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVN(Deamidated)LVGYEK MGYG000002854_00976 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Peptostreptococcaceae|g__Peptacetobacter|s__Peptacetobacter sp900539645|m__MGYG000002854 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,22HEI@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVPAFVSGK MGYG000002494_02496;MGYG000002506_03710;MGYG000002534_04602;MGYG000002323_03976 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,3XPW4@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupA 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006323,GO:0006351,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:1990104,GO:1990178,GO:2001141 1.0 - 1.0 ko:K03530,ko:K05787 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 1471151 0 0 2189095 0 0 1575715 1946436 0 0 0 1756945 0 0 2108338 0 0 1718589 0 2042616 0 2204837 1702344 0 0 0 0 0 0 0 1519973 1856926 1983818 1718692 0 1377905 0 0 1407480 0 0 1382982 0 0 1803189 747540 0 0 0 1151450 0 0 1194358 0 3374026 1531984 0 1185029 0 1022266 1431106 0 0 0 0 0 0 0 1339395 1167880 933477 1156126 0 1256443 0 0 1274882 0 0 1708204 0 0 1636342 1027301 0 0 0 1344081 0 0 793313 0 1045370 932652 0 1496763 0 2250593 1007945 0 0 0 0 0 0 0 797785 1180346 1217497 1406473 0 1189966 0 0 2547262 0 0 2548297 0 0 1755612 1986550 0 0 0 1899000 0 0 1453449 0 1891804 1851558 0 2053848 0 1528176 2482269 0 0 0 0 0 0 0 2224782 3218206 1999135 2794691 0 1848201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335276 0 0 0 0 0 0 440661 0 0 0 0 0 0 0 0 0 379249 0 0 0 280659 -AANVS(Deoxy[S](Ser->Ala)LVGTEK MGYG000000184_02439 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A luti|m__MGYG000000184 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10382705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVSLVGYEK MGYG000004087_00692;MGYG000001564_03645;MGYG000000205_00403;MGYG000000198_03144 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 0.75 186801|Clostridia 0.75 CQ 1.0 PFAM microcompartments protein 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 1276512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1265940 0 1454122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 539579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2361860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2711885 0 2811170 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5143739 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4855153 0 3609205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302551 0 469838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVTLIGK MGYG000000092_00836;MGYG000001311_03739;MGYG000000092_00835;MGYG000001171_01490;MGYG000000198_01506;MGYG000000099_01306;MGYG000000099_01305;MGYG000001367_03226;MGYG000000150_00833;MGYG000001698_02372;MGYG000000150_00816;MGYG000001698_02371;MGYG000003185_00408;MGYG000004630_01930;MGYG000000413_00044;MGYG000004630_01931;MGYG000000359_01134;MGYG000000359_01133;MGYG000001617_00515;MGYG000000179_01371;MGYG000000233_02830;MGYG000000359_00758;MGYG000003589_02226 domain d__Bacteria 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia 0.30434782608695654 186801|Clostridia 1.0 CQ 1.0 Carbon dioxide concentrating mechanism carboxysome shell protein 0.30434782608695654 - 0.6956521739130435 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 16932820 14478121 7769544 15000920 0 14834381 14023032 0 15019965 16983116 0 0 0 17766748 0 0 0 0 0 0 0 8675562 0 0 0 18494753 19085038 0 0 0 10386501 15134925 0 4421103 0 15791934 0 0 14166102 7019910 13315162 13214181 0 9550854 7826489 12503659 0 0 0 12079872 0 13331346 16551181 0 0 0 13637916 15958765 0 9320509 0 8316013 11908936 13444906 11520723 0 0 14172239 7157545 10315423 11757686 10346214 12431562 0 0 13944165 0 9527558 0 12932728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7396979 0 0 0 0 0 0 0 0 10973069 0 0 0 0 0 0 0 0 0 0 0 0 7402470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVTLIGK(Lys->Arg) MGYG000000092_00836;MGYG000001311_03739;MGYG000000092_00835;MGYG000001171_01490;MGYG000000198_01506;MGYG000000099_01306;MGYG000000099_01305;MGYG000001367_03226;MGYG000000150_00833;MGYG000001698_02372;MGYG000000150_00816;MGYG000001698_02371;MGYG000003185_00408;MGYG000004630_01930;MGYG000000413_00044;MGYG000004630_01931;MGYG000000359_01134;MGYG000000359_01133;MGYG000001617_00515;MGYG000000179_01371;MGYG000000233_02830;MGYG000000359_00758;MGYG000003589_02226 domain d__Bacteria 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia 0.30434782608695654 186801|Clostridia 1.0 CQ 1.0 Carbon dioxide concentrating mechanism carboxysome shell protein 0.30434782608695654 - 0.6956521739130435 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 816217 0 0 0 0 798092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 638613 0 0 0 0 520522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVTLLGK MGYG000000198_01506;MGYG000001367_03225;MGYG000001367_03226;MGYG000000150_00833;MGYG000002829_04822;MGYG000000150_00816;MGYG000003185_00408;MGYG000000359_01134;MGYG000000413_00044;MGYG000000359_01133;MGYG000002829_01657;MGYG000001617_00515;MGYG000000179_01371;MGYG000000233_02830;MGYG000000359_00758;MGYG000003589_02226 domain d__Bacteria 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 0.3125 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 0.5 - 0.5625 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15301137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8128000 0 0 16992188 0 0 0 10339795 0 0 0 0 0 0 0 0 0 0 10147913 0 0 0 0 0 0 0 0 0 15177528 0 0 13161053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7703442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1720418 0 0 0 0 15459581 0 0 0 0 0 0 0 0 1302759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVTLVGK MGYG000000152_02876 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lacrimispora|s__Lacrimispora sp902363835|m__MGYG000000152 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 1.0 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 584253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1315488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVV(Val->Ala)LVGTEK MGYG000000175_02141;MGYG000000127_01924;MGYG000004799_00495;MGYG000003427_01862;MGYG000002596_02058;MGYG000000268_01896 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.5 - 1.0 - 1.0 - 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6117305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANVVLVGTEK MGYG000000175_02141;MGYG000000127_01924;MGYG000004799_00495;MGYG000003427_01862;MGYG000002596_02058;MGYG000000268_01896 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.5 - 1.0 - 1.0 - 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 793806 0 0 0 745038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 936379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94243 0 0 0 721411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 768881 0 0 0 5821062 0 0 0 0 0 0 0 0 2684436 0 0 0 0 0 0 0 0 458734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 195159 0 0 0 0 0 0 0 0 0 0 -AANVYLIGK MGYG000003142_02726;MGYG000003142_02725 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium_J|s__Clostridium_J sp900547625|m__MGYG000003142 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 1.0 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4525462 0 0 0 0 0 0 0 0 0 0 4130646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANWLLR MGYG000003693_00985;MGYG000000243_02341;MGYG000000196_00133 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,2FNRM@200643|Bacteroidia,4AKT2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 susD 1.0 GO:0001871,GO:0003674,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0006073,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0019867,GO:0030246,GO:0030247,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0046872,GO:0071704,GO:2001070 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 1311155 0 0 0 0 0 0 0 0 0 0 0 923258 881036 0 0 0 0 1335960 0 0 0 0 1059273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1116073 0 0 0 0 2071192 0 0 0 0 1533754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 763467 0 0 0 0 0 0 0 0 0 0 0 298571 1513409 0 0 0 0 1410350 0 0 0 0 1170709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159433 0 0 0 0 2452268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AANYALK MGYG000002438_01848 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,22WFC@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Domain of Unknown Function (DUF349) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 177127 0 0 0 0 0 0 0 0 309008 0 0 0 0 0 0 0 0 260137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280632 0 0 0 0 0 0 0 0 375214 0 0 0 0 0 0 0 0 350615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 465386 0 0 0 0 0 0 0 0 1066920 0 0 0 0 0 0 0 0 702578 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 593080 0 0 0 0 0 0 0 0 1287617 0 0 0 0 0 0 0 0 847410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1733105 0 0 0 0 0 0 0 0 1917833 0 0 0 0 0 0 0 0 1938608 0 0 0 0 0 0 0 0 -AANYLSIGQIYLR MGYG000000756_01025;MGYG000003683_00701 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 437944 0 405778 382807 0 29535 130717 40809 0 0 180279 0 690041 0 0 382785 0 56740 0 757922 0 0 49544 0 0 33758 0 32988 106174 0 205234 0 217713 0 0 0 0 455048 930564 0 2008448 1165044 1139229 2261416 1174281 1002502 0 1034899 1581189 0 3994070 419587 0 1141164 0 6976505 0 710144 0 1032567 1739609 3718814 0 603141 1351138 3618247 1540498 0 4144431 0 1622918 0 0 914202 889239 6883825 1359068 0 241405 252979 0 430029 0 1392705 0 774843 0 0 581964 0 0 1490419 0 0 0 1413367 0 1821905 0 110019 0 0 1006015 0 435312 0 0 0 4314719 0 0 0 0 0 0 0 0 0 1200037 0 159979 120773 0 0 0 0 0 0 0 0 0 0 0 349078 0 0 0 478639 0 481264 510006 309135 420138 0 0 0 203735 0 0 498437 234202 1735330 244982 0 82116 256545 666769 462694 90230 0 0 2528031 7790634 0 455044 0 0 243277 0 148242 0 364771 0 0 119614 421340 0 268768 235244 0 0 0 4674915 0 0 0 0 0 0 313630 -AANYVASK MGYG000000243_00067;MGYG000002478_04559 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,4AKMP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways 1.0 none 1.0 0 0 1208219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 829782 0 0 0 0 0 0 0 1610554 0 0 0 0 1262921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158000 0 0 0 0 0 0 0 71364 0 0 0 0 246893 0 0 264242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227476 0 0 0 0 0 0 0 240274 0 0 0 0 0 0 0 123980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226506 0 0 0 0 0 -AANYWR MGYG000000243_03182 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0457@1|root,COG0457@2|Bacteria,4NG3F@976|Bacteroidetes,2FM0I@200643|Bacteroidia,4AKP7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 3056726 0 0 0 0 1014826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1731775 0 2882940 0 0 0 0 2549516 0 0 584709 0 0 0 0 774691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485588 0 505350 0 0 0 0 539257 0 0 164618 0 0 0 0 226181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299567 0 303674 0 0 0 0 275864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 240439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215312 0 0 0 0 0 0 0 -AAPAAAPAAAAA(Ala->Pro)K MGYG000002506_04250 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,3XP9X@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) 1.0 aceE 1.0 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.0 1.2.4.1 1.0 ko:K00163 1.0 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 1.0 M00307 1.0 R00014,R00209,R01699,R03270 1.0 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 e_coli_core.b0114,iAF1260.b0114,iBWG_1329.BWG_0107,iE2348C_1286.E2348C_0117,iEC55989_1330.EC55989_0107,iECDH10B_1368.ECDH10B_0094,iECDH1ME8569_1439.ECDH1ME8569_0108,iECH74115_1262.ECH74115_0121,iECIAI1_1343.ECIAI1_0112,iECNA114_1301.ECNA114_0106,iECO103_1326.ECO103_0114,iECO111_1330.ECO111_0115,iECO26_1355.ECO26_0116,iECSE_1348.ECSE_0114,iECSF_1327.ECSF_0127,iECSP_1301.ECSP_0115,iECUMN_1333.ECUMN_0111,iECW_1372.ECW_m0111,iECs_1301.ECs0118,iEKO11_1354.EKO11_3802,iETEC_1333.ETEC_0110,iEcDH1_1363.EcDH1_3488,iEcE24377_1341.EcE24377A_0116,iEcHS_1320.EcHS_A0118,iEcSMS35_1347.EcSMS35_0124,iEcolC_1368.EcolC_3545,iG2583_1286.G2583_0118,iJO1366.b0114,iJR904.b0114,iUMNK88_1353.UMNK88_112,iWFL_1372.ECW_m0111,iY75_1357.Y75_RS00580,iZ_1308.Z0124 1.0 Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate dehydrogenase (acetyl-transferring). pyruvic dehydrogenase. It is a component (in multiple copies) of EC 1.2.1.104 in which it is bound to a core of molecules of EC 2.3.1.12, which also binds multiple copies of EC 1.8.1.4.-!-It does not act on free lipoamide or lipoyllysine, but only on the lipoyllysine residue in EC 2.3.1.12. H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + pyruvate = CO2 + N(6)-[(R)-S(8)- acetyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1721993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAAPAAAPK MGYG000004769_01105;MGYG000004276_00434 domain d__Bacteria 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 0.5 909932|Negativicutes 0.5 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 0.5 gcdC 1.0 - 1.0 4.1.1.70 0.5 ko:K01615 0.5 ko00362,ko00650,ko01120,map00362,map00650,map01120 0.5 - 1.0 R03028 0.5 RC00832 0.5 ko00000,ko00001,ko01000,ko02000 0.5 3.B.1.1.3 0.5 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 0.5 0.5 0.5 0.5 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2062630 846454 0 0 603210 0 0 493469 934411 0 0 773365 0 377342 0 0 0 0 0 0 0 0 431066 0 860390 0 0 0 0 0 0 911510 0 0 0 0 911172 815051 482587 481621 0 0 1201166 0 0 508682 930429 0 0 1021186 0 905620 0 0 2253064 0 0 0 854358 1925405 986072 0 892591 0 2185434 0 0 0 0 742268 0 0 906467 0 618245 699734 0 0 0 0 0 0 0 948246 120415 0 0 326759 0 1169197 0 0 612533 0 0 0 0 0 0 0 389840 0 0 0 0 0 0 757486 0 1284158 1094510 1311147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAAPAAPK MGYG000002279_00505;MGYG000002992_01786;MGYG000000038_00467 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,27VPV@189330|Dorea 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 2246496 0 971570 0 0 0 1435089 0 0 1785772 0 0 2550551 0 0 0 3019834 0 0 0 0 0 0 1657806 1600776 0 0 0 0 0 1580731 0 0 1327780 1602327 643932 0 0 0 0 2025572 0 0 0 0 0 0 2059126 0 0 2132033 0 0 0 3309760 2076429 0 0 0 0 0 2333011 2130784 0 0 0 0 0 0 0 0 0 0 0 0 0 1312875 0 0 0 0 0 0 0 0 0 0 0 3216108 0 0 0 0 5684670 0 0 0 0 0 0 3407325 0 0 0 0 0 2644739 0 0 1615987 1249559 0 0 0 1683651 0 1582385 0 0 0 0 0 0 1647162 0 0 2218492 0 0 0 1270934 0 0 0 0 0 0 0 0 0 0 0 0 0 1978253 0 0 2483058 1936917 1365723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAAPAAPR(Arg->Lys) MGYG000003937_01659 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 CBM50 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 1720506 0 0 0 0 0 4262818 0 0 0 0 2916389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAAPAPAAK MGYG000004769_01105 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 623103 0 0 0 0 0 0 0 0 0 0 0 548440 0 0 0 0 0 0 0 0 0 0 0 0 632406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 728811 0 0 0 0 0 0 0 1008568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAAPAPAAKPVAAGAATISAPMPGK MGYG000004769_01105 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463696 0 506054 0 0 0 0 0 0 0 0 0 0 453387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAAPK MGYG000000743_02099;MGYG000000031_02585;MGYG000003486_02407;MGYG000004769_01105;MGYG000000135_00626;MGYG000000467_01964;MGYG000003012_01442;MGYG000000170_01348;MGYG000000249_01881;MGYG000004271_01071;MGYG000000325_01536;MGYG000000205_01179;MGYG000002544_00055;MGYG000004482_00849;MGYG000000806_02004;MGYG000004869_00217;MGYG000000212_00763;MGYG000000201_01806;MGYG000000142_00945;MGYG000000171_00279;MGYG000000150_03570;MGYG000002802_01947;MGYG000000213_01127;MGYG000002298_00907;MGYG000002312_01224;MGYG000000002_01398;MGYG000000022_01358;MGYG000004839_00782;MGYG000004884_00770;MGYG000000216_00194;MGYG000000271_00470;MGYG000004719_00224;MGYG000003891_01453;MGYG000001338_01632;MGYG000000255_00810;MGYG000001689_02350;MGYG000004501_00375;MGYG000000182_00099;MGYG000003215_02241;MGYG000002651_00052;MGYG000000118_00820;MGYG000003684_05217;MGYG000000200_00817;MGYG000000233_00100;MGYG000004701_00748;MGYG000000633_01449;MGYG000002794_00735;MGYG000004276_00434 domain d__Bacteria 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 0.3541666666666667 186801|Clostridia 0.8333333333333334 I 0.8125 Biotin-requiring enzyme 0.6666666666666666 gcdC 0.8125 - 0.9791666666666666 - 0.9375 - 0.8541666666666666 - 0.8958333333333334 - 0.9375 - 0.9583333333333334 - 0.9583333333333334 - 0.8541666666666666 - 0.9583333333333334 - 1.0 - 1.0 Biotin_lipoyl 0.8125 - 1.0 - 1.0 - 1.0 - 0.9583333333333334 - - - - 0.9375 0.9375 0.9375 0.9375 0.8958333333333334 none 1.0 2352666 4033891 1819253 0 2523788 1467319 0 1698875 2309018 1990550 2148809 1327318 0 1665969 2207679 1981481 0 0 2100862 415791 1658350 2199101 1823716 1965568 1660044 0 0 2122447 2669941 1708324 4554575 1850634 2710548 2340319 1318862 1958289 1485022 5032572 1630988 3825662 711496 0 2242742 1420032 2174199 2530462 0 2188615 2509973 0 0 0 0 0 1129318 820040 1515705 1378326 873529 821485 1544616 1856416 1048010 879153 0 1947131 2791990 655581 10336858 2402429 736196 1325377 0 1025991 1339559 1242840 1121447 0 0 0 0 0 663904 0 604693 1563732 0 420685 1091341 0 1364191 1290355 0 0 953467 0 1299062 1222277 0 1982135 0 1390600 1345733 1069279 0 0 0 1971775 2462097 1922517 1525095 0 782658 0 0 0 0 0 516858 705720 3599413 558941 1213123 0 1140560 0 1598664 0 439514 0 527642 279536 643988 0 709631 0 436801 629367 0 328359 555216 664116 0 370031 0 1849629 724096 433499 558825 537121 590983 0 0 6211947 1423222 0 1088589 0 0 0 0 0 0 0 294788 0 1180177 885593 0 0 0 805654 0 810648 1528491 880267 0 0 0 0 0 1797453 1508097 1184090 0 788406 0 1065817 922259 1443318 -AAPAAAPKAAAP MGYG000000200_00817 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp003471165|m__MGYG000000200 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1899454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAAPKAAAPK(PS_Hapten)AAPAPK MGYG000000182_00099 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Mitsuokella|s__Mitsuokella sp003458855|m__MGYG000000182 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1377494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAAPKAAPAA MGYG000004769_01105 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2149549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAADFEGSLQQVGNK MGYG000001337_04011 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis|m__MGYG000001337 1.0 COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,2FPYJ@200643|Bacteroidia,4APBK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Domain of Unknown Function with PDB structure (DUF3857) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF3857,DUF3858,Transglut_core 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 533247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 710730 0 0 0 0 688095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAGAAGAAAEEK MGYG000002777_00224 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900545785|m__MGYG000002777 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4H4X8@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1061422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAGAGEA(Ala->Val)AAAEK MGYG000002867_00700;MGYG000001562_01082;MGYG000001420_00134;MGYG000003279_00958;MGYG000002203_00881;MGYG000002007_00362;MGYG000004658_01198;MGYG000004756_01180;MGYG000000003_02516 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAGAGEAAA(Ala->Val)AEK MGYG000002867_00700;MGYG000001562_01082;MGYG000001420_00134;MGYG000003279_00958;MGYG000002203_00881;MGYG000002007_00362;MGYG000004658_01198;MGYG000004756_01180;MGYG000000003_02516 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1063977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAGAGEAAAAEK MGYG000002867_00700;MGYG000001562_01082;MGYG000001420_00134;MGYG000003279_00958;MGYG000002203_00881;MGYG000002007_00362;MGYG000004658_01198;MGYG000004756_01180;MGYG000000003_02516 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 1951439 0 678656 1719591 827056 1449641 1486561 1088766 1746362 1367492 615815 1411720 810946 1483853 2088866 1116205 1502558 0 1825958 1628029 1511293 906354 0 1529281 1432481 1725421 1937863 0 1481998 2173247 753735 1189664 710940 1283424 1461995 2075291 1653582 655894 773908 0 840217 737812 496317 690847 521950 629044 142909 821660 453078 1227155 425681 974900 0 0 947758 0 725113 731646 644188 609569 0 0 753639 675981 178705 0 667538 0 525996 751668 713243 0 714791 265443 994452 915208 1031991 0 1244088 697797 858003 468729 735330 772274 998122 781905 566182 710346 705892 1082302 829704 504588 568706 0 566029 869224 1067968 435626 0 335301 507324 800204 778620 0 616759 1156014 468126 297328 642219 1075455 888669 1280163 772739 991036 0 0 388160 168361 200921 290045 418042 464011 547476 493563 415234 350771 512699 276479 703879 0 0 0 603532 383123 461747 560588 0 380908 282181 569274 498810 0 569039 0 0 0 146129 310890 437320 349988 534900 582429 155678 0 254872 201906 274049 230340 380990 252202 353626 0 238957 173279 251217 139372 305878 220581 310197 0 318400 529631 0 250000 0 357764 475856 464910 381548 0 119700 400019 176075 158492 198474 0 532828 386664 194476 214827 -AAPAAGAGEAAVAEK MGYG000000074_01766 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 290947 0 0 0 560181 444340 464303 0 0 495612 424525 0 0 0 0 323896 0 0 0 0 0 0 0 0 0 1638433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1655090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433988 0 0 0 0 0 0 0 256124 303922 249280 0 272965 0 0 0 424545 315741 0 0 0 0 509940 0 166443 0 264813 197676 0 408254 204305 0 0 0 0 318705 0 734497 1293881 0 0 0 0 0 0 479054 774917 1253735 0 1127354 1250399 0 0 0 1465116 1343234 0 0 0 0 1782646 0 1106810 0 1130313 1063664 0 1104049 844769 0 1133939 0 0 556667 0 2645523 2824716 0 0 0 0 0 0 4036077 2279904 0 3326431 0 0 3788844 0 0 0 0 3744312 0 0 0 0 0 0 0 2997436 5952128 0 0 3887183 0 0 0 0 0 -AAPAAGAGSIQVK MGYG000001310_00451 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 1316311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1889083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2350617 0 2545840 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAKPVEAPK MGYG000002961_01600 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900542275|m__MGYG000002961 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,2GJU4@201174|Actinobacteria,4CUBT@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 TIGRFAM PTS system, fructose subfamily, IIC 1.0 - 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS_EIIA_2,PTS_EIIC,PTS_IIB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS);Metabolic pathways;Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAPAAAPK MGYG000002802_01947;MGYG000000271_00470;MGYG000004271_01071 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 I 0.6666666666666666 PFAM biotin lipoyl attachment domain-containing protein 0.6666666666666666 gcdC 0.6666666666666666 - 1.0 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1944183 0 0 0 0 0 0 0 1284400 1053551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1555545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAPAAPK MGYG000000022_01358 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 791489 0 0 0 0 0 321619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141036 0 0 0 0 0 1730537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372331 0 0 0 0 0 757427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAPAK MGYG000003266_00143;MGYG000000089_00231 domain d__Bacteria 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,2GJU4@201174|Actinobacteria,4CUBT@84998|Coriobacteriia 0.5 84998|Coriobacteriia 0.5 G 0.5 TIGRFAM PTS system, fructose subfamily, IIC 0.5 - 0.5 - 0.5 2.7.1.202 0.5 ko:K02768,ko:K02769,ko:K02770 0.5 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 0.5 M00273 0.5 R03232 0.5 RC00017,RC03206 0.5 ko00000,ko00001,ko00002,ko01000,ko02000 0.5 4.A.2.1 0.5 - 0.5 - 0.5 PTS_EIIA_2,PTS_EIIC,PTS_IIB 0.5 - 0.5 - 0.5 - 0.5 - 0.5 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 0.5 0.5 0.5 0.5 Phosphotransferase system (PTS);Metabolic pathways;Microbial metabolism in diverse environments;Fructose and mannose metabolism 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 2518037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1015030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAPAQGGIPK MGYG000000171_01275 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3WS7A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Glucose dehydrogenase C-terminus 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2235960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAAPK MGYG000000133_01634;MGYG000000022_01358;MGYG000002042_00590 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 I 0.6666666666666666 Biotin-requiring enzyme 0.6666666666666666 gcdC 0.6666666666666666 - 1.0 - 1.0 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 0.6666666666666666 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 109590 167682 0 0 0 0 0 0 0 0 0 0 0 0 0 506184 0 0 0 0 347073 0 0 0 0 460852 0 0 0 0 160428 0 0 0 0 352864 0 0 78002 103500 0 0 0 0 0 0 0 0 0 0 0 0 0 140636 0 0 0 0 183736 0 0 0 0 285924 0 0 0 0 73303 0 0 0 0 48703 0 0 114275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135702 0 0 0 0 161521 0 0 0 0 411353 0 0 0 0 86579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49704 0 0 0 0 188822 0 0 0 0 0 0 0 0 0 0 0 0 170508 1715944 0 0 0 0 0 0 0 0 0 0 0 0 0 167823 0 0 0 0 240378 0 0 0 0 287449 0 0 0 0 619544 0 0 0 0 0 -AAPADEVAAPAVEAEEGGIHK MGYG000001313_03230 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 821842 0 0 0 0 577722 0 0 0 0 642265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPADPILGLADLFR MGYG000002506_00254;MGYG000003883_00875 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,3XNR8@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 L-aspartate:2-oxoglutarate aminotransferase activity 1.0 aspC 1.0 GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.0 2.6.1.1,2.6.1.57 1.0 ko:K00813,ko:K00832 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 M00024,M00025,M00034,M00040 1.0 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 iPC815.YPO1410,iSFxv_1172.SFxv_1000 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 aspartate transaminase. | aromatic-amino-acid transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. | L-methionine can also act as donor, more slowly.-!-Oxaloacetate can act as acceptor.-!-Controlled proteolysis converts the enzyme to EC 2.6.1.1. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. | 2-oxoglutarate + an aromatic L-alpha-amino acid = an aromatic oxo-acid + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Cysteine and methionine metabolism;Arginine and proline metabolism;Phenylalanine metabolism;Phenylalanine, tyrosine and tryptophan biosynthesis;Alanine, aspartate and glutamate metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Isoquinoline alkaloid biosynthesis;Tyrosine metabolism;Novobiocin biosynthesis;Tropane, piperidine and pyridine alkaloid biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4396240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAEAPAAE(Glu->Ala)AK MGYG000000301_00933 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900541985|m__MGYG000000301 1.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3Y0FB@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA 1.0 accB 1.0 - 1.0 - 1.0 ko:K02160 1.0 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 1.0 M00082,M00376 1.0 R00742 1.0 RC00040,RC00367 1.0 ko00000,ko00001,ko00002 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Fatty acid metabolism;Fatty acid biosynthesis;Carbon fixation pathways in prokaryotes;Metabolic pathways;Biosynthesis of secondary metabolites;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2944481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAEEAAAGPSEVTVTLTDVGGTK MGYG000000223_01551 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,36IQP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 780509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371447 0 860895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAGAGAAPAEEKSEFDVVLK MGYG000003022_00741 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella|s__Parasutterella sp000980495|m__MGYG000003022 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,1KKSF@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 315460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 976030 0 0 0 1353745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAGGAAAPAEEKSEFDVVLK MGYG000003352_00737 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella|s__Parasutterella sp900766055|m__MGYG000003352 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,1KKSF@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 782243 0 1652754 848607 0 0 0 0 0 839175 0 0 0 0 0 0 646938 0 407773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1002257 0 1121083 1004621 0 0 0 0 0 545985 0 0 0 0 0 0 534833 0 435953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAGGAGSIEVK MGYG000002279_00505;MGYG000002992_01786 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,27VPV@189330|Dorea 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1092491 0 0 0 1511548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1978193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPALLEPIMK MGYG000000562_01882;MGYG000000187_02028 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,25VFH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1145501 0 0 0 0 1118856 0 0 0 0 1377932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336124 0 0 0 0 271763 0 0 0 0 321613 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 771251 0 0 0 0 922247 0 0 0 0 1020160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1510336 0 0 0 0 1022316 0 0 0 0 1770142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721791 0 0 0 0 1013355 0 0 0 0 1128792 0 0 0 0 0 0 0 0 0 0 -AAPANIK MGYG000000271_02509;MGYG000004271_00777 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 1179468 0 0 0 0 999349 0 0 864221 0 697875 1039782 0 543886 0 0 1108181 0 0 0 0 1196121 0 1011414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350237 0 0 0 0 84913 0 0 101441 0 416564 38017 0 0 0 0 218246 0 0 0 0 312732 0 298951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31922 0 0 0 0 0 0 0 111863 0 73869 0 0 128184 0 0 0 0 0 0 0 67706 0 47630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 142308 0 0 64116 0 203734 0 0 407156 0 0 40785 0 0 0 0 0 0 248304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682288 0 0 0 0 1234724 0 0 757793 0 521851 529862 0 611749 0 0 748376 0 0 0 0 341466 0 470038 0 0 0 0 0 0 0 0 -AAPAPAAAAAPAAPAAPASAGAVEVK MGYG000002545_00187 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_G|m__MGYG000002545 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 666863 0 0 0 0 609216 0 0 0 0 607579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288426 0 0 0 0 310216 0 0 0 0 344267 0 0 0 0 0 0 0 0 0 0 -AAPAPAAAPAPA(Ala->Pro)AK MGYG000002535_03464 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter|s__Citrobacter gillenii|m__MGYG000002535 1.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,3WWKR@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 C 1.0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) 1.0 aceF 1.0 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 1.0 2.3.1.12 1.0 ko:K00627 1.0 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 1.0 M00307 1.0 R00209,R02569 1.0 RC00004,RC02742,RC02857 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iETEC_1333.ETEC_0111,iSSON_1240.SSON_0123,iYL1228.KPN_00119 1.0 2-oxoacid_dh,Biotin_lipoyl,E3_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 dihydrolipoyllysine-residue acetyltransferase. transacetylase X. A multimer (24-mer or 60-mer, depending on the source) of this enzyme forms the core of the pyruvate dehydrogenase multienzyme complex, and binds tightly both EC 1.2.4.1 and EC 1.8.1.4.-!-The lipoyl group of this enzyme is reductively acetylated by EC 1.2.4.1, and the only observed direction catalyzed by EC 2.3.1.12 is that where the acetyl group is passed to coenzyme A. acetyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = CoA + N(6)- [(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAPAAAPAPAA(Ala->Pro)K MGYG000002535_03464 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter|s__Citrobacter gillenii|m__MGYG000002535 1.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,3WWKR@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 C 1.0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) 1.0 aceF 1.0 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 1.0 2.3.1.12 1.0 ko:K00627 1.0 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 1.0 M00307 1.0 R00209,R02569 1.0 RC00004,RC02742,RC02857 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iETEC_1333.ETEC_0111,iSSON_1240.SSON_0123,iYL1228.KPN_00119 1.0 2-oxoacid_dh,Biotin_lipoyl,E3_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 dihydrolipoyllysine-residue acetyltransferase. transacetylase X. A multimer (24-mer or 60-mer, depending on the source) of this enzyme forms the core of the pyruvate dehydrogenase multienzyme complex, and binds tightly both EC 1.2.4.1 and EC 1.8.1.4.-!-The lipoyl group of this enzyme is reductively acetylated by EC 1.2.4.1, and the only observed direction catalyzed by EC 2.3.1.12 is that where the acetyl group is passed to coenzyme A. acetyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = CoA + N(6)- [(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2488480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAPAAAPAPAPA(Ala->Lys) MGYG000000255_00870;MGYG000000205_00592 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,2208C@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 CBM50 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2455535 0 0 0 0 0 0 0 0 0 1911151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAPAAAPAPK MGYG000001365_01216;MGYG000004769_00268 family d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 909693 0 0 916905 0 0 0 0 667287 0 0 0 0 1288321 0 0 0 0 367459 474494 1065774 0 0 0 574037 469589 802560 0 0 575224 0 0 0 677995 566680 259676 321810 0 18052349 19846840 20890174 16004057 19284352 15518796 12971788 21176603 17542681 19450618 18963070 18966400 12950751 19843125 15903901 17060039 19237805 0 15848609 13275021 14747615 17319285 2622997 14835963 16530550 15780139 14371315 0 18567643 15598349 15422437 18474061 20261970 18890794 22998959 15918256 15762328 19071993 8805370 8302296 9718059 6379610 10463716 9881268 9225966 10936012 6817522 8558725 11911688 6763841 11768415 6872345 7930981 6778824 3966291 4797420 8059555 7402540 7117635 7615092 4015931 8896433 8447506 8627623 7727077 4092802 7584098 6839687 10840610 7189239 7295768 9910621 13303949 8280634 8657312 5070131 1377866 1320346 2673942 1313841 1556919 1231593 1519812 1870515 1209114 1424781 1698613 1422342 2206615 982341 1349537 1053347 1101240 0 1589764 911982 1421154 1826566 247769 1723352 1161478 1211417 1175458 0 1263064 1550486 1714665 1659568 2825467 1526833 1781046 1486166 1291760 1999061 0 0 14296024 17377723 12446038 15216731 6985764 17389097 11636364 6714867 12568319 9729893 16375206 7532711 9550585 6748232 9620448 16453464 10008684 9347183 6815030 7903166 20517271 16673268 14518802 12931639 0 14727055 7098084 9920244 15309053 19944331 10535200 10144122 15526504 13547464 10343675 16716865 -AAPAPAAAPAPKA(Ala->Pro)A MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2427056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1943135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAPAAAPAPKAA(Ala->Pro) MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Butanoate metabolism;Microbial metabolism in diverse environments;Benzoate degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3240781 0 0 0 0 0 4117581 2717795 0 0 0 0 0 0 0 0 0 0 0 1833154 0 0 0 0 0 0 2542424 0 0 0 0 2165358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAPAAAPAQAAKPAAAPAAK MGYG000002494_03015 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,3ZJ1Q@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 C 1.0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) 1.0 aceF 1.0 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 1.0 2.3.1.12 1.0 ko:K00627 1.0 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 1.0 M00307 1.0 R00209,R02569 1.0 RC00004,RC02742,RC02857 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iETEC_1333.ETEC_0111,iSSON_1240.SSON_0123,iYL1228.KPN_00119 1.0 2-oxoacid_dh,Biotin_lipoyl,E3_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 dihydrolipoyllysine-residue acetyltransferase. transacetylase X. A multimer (24-mer or 60-mer, depending on the source) of this enzyme forms the core of the pyruvate dehydrogenase multienzyme complex, and binds tightly both EC 1.2.4.1 and EC 1.8.1.4.-!-The lipoyl group of this enzyme is reductively acetylated by EC 1.2.4.1, and the only observed direction catalyzed by EC 2.3.1.12 is that where the acetyl group is passed to coenzyme A. acetyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = CoA + N(6)- [(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572797 0 338033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAPAAAPK MGYG000000076_00252;MGYG000003291_00824;MGYG000001300_00242;MGYG000001417_02207;MGYG000000245_00298;MGYG000003166_01306 domain d__Bacteria 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 0.5 186801|Clostridia 0.8333333333333334 I 0.8333333333333334 Biotin-requiring enzyme 0.5 gcdC 0.8333333333333334 - 1.0 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 none 1.0 1537241 0 1273853 1837800 0 879713 1328296 799017 0 0 0 1335687 1302963 1819746 1154285 911605 1026724 0 0 1571500 1189510 1113319 0 1419428 1212716 1637593 0 0 0 0 0 0 1602975 0 0 0 1471414 1442151 0 0 8497305 14375672 0 10351660 16623734 6450414 11744471 0 0 10667918 8800435 14380920 12160188 0 0 0 16105568 11605120 5860166 8426729 0 8635780 15035437 12760702 0 0 0 0 0 0 13056900 0 0 0 13970987 7650731 823223 0 1425618 1278893 0 546859 1757610 1171745 1209737 0 0 1146150 1363718 978361 1164063 1038503 752229 0 1307863 0 0 2768896 0 3136230 1637645 1388391 0 0 0 1121811 0 0 1318834 1343831 0 0 1004724 1297959 5677317 0 0 6057363 0 9212553 9420397 4037311 7366955 0 0 15888296 7570956 7000641 8047576 7000840 6369678 0 12667117 6724186 3089744 13602412 0 12808506 6668475 6648246 0 0 0 6510243 0 0 9562672 15824044 0 0 6849434 9096690 0 0 134832 0 0 0 212382 113148 0 0 0 0 0 0 0 0 200877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230071 -AAPAPAAAPKAAAGAAGAVAVK MGYG000001300_00242 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754078 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAPAAK MGYG000002506_04250;MGYG000004769_00268 domain d__Bacteria 1.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,3XP9X@561|Escherichia 0.5 1236|Gammaproteobacteria 0.5 F 0.5 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) 0.5 aceE 0.5 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 0.5 1.2.4.1 0.5 ko:K00163 0.5 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 0.5 M00307 0.5 R00014,R00209,R01699,R03270 0.5 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 0.5 br01601,ko00000,ko00001,ko00002,ko01000 0.5 - 0.5 - 1.0 e_coli_core.b0114,iAF1260.b0114,iBWG_1329.BWG_0107,iE2348C_1286.E2348C_0117,iEC55989_1330.EC55989_0107,iECDH10B_1368.ECDH10B_0094,iECDH1ME8569_1439.ECDH1ME8569_0108,iECH74115_1262.ECH74115_0121,iECIAI1_1343.ECIAI1_0112,iECNA114_1301.ECNA114_0106,iECO103_1326.ECO103_0114,iECO111_1330.ECO111_0115,iECO26_1355.ECO26_0116,iECSE_1348.ECSE_0114,iECSF_1327.ECSF_0127,iECSP_1301.ECSP_0115,iECUMN_1333.ECUMN_0111,iECW_1372.ECW_m0111,iECs_1301.ECs0118,iEKO11_1354.EKO11_3802,iETEC_1333.ETEC_0110,iEcDH1_1363.EcDH1_3488,iEcE24377_1341.EcE24377A_0116,iEcHS_1320.EcHS_A0118,iEcSMS35_1347.EcSMS35_0124,iEcolC_1368.EcolC_3545,iG2583_1286.G2583_0118,iJO1366.b0114,iJR904.b0114,iUMNK88_1353.UMNK88_112,iWFL_1372.ECW_m0111,iY75_1357.Y75_RS00580,iZ_1308.Z0124 0.5 Transketolase_N 0.5 - 1.0 - 1.0 - 1.0 - 1.0 pyruvate dehydrogenase (acetyl-transferring). pyruvic dehydrogenase. It is a component (in multiple copies) of EC 1.2.1.104 in which it is bound to a core of molecules of EC 2.3.1.12, which also binds multiple copies of EC 1.8.1.4.-!-It does not act on free lipoamide or lipoyllysine, but only on the lipoyllysine residue in EC 2.3.1.12. H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + pyruvate = CO2 + N(6)-[(R)-S(8)- acetyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase]. 0.5 0.5 0.5 0.5 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1947971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1119680 0 0 0 2486321 1342470 1102048 1133960 0 0 0 0 0 0 0 0 0 0 1748983 0 0 0 0 0 0 0 0 0 0 0 0 1830492 0 0 431650 532667 0 1226833 240689 0 906438 0 0 1146344 0 0 0 0 0 1291506 0 0 491302 0 1259190 0 0 0 808626 540461 820275 0 0 0 0 871396 0 1069154 402715 0 0 0 0 0 0 0 0 763105 0 517774 0 622172 0 861220 0 0 0 924927 0 0 0 0 499986 0 0 0 0 0 0 0 0 0 0 0 0 694822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAPAAPAAPK MGYG000002224_01088 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900540455|m__MGYG000002224 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 CBM50 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8732044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6584726 0 0 0 0 0 0 0 0 0 0 0 -AAPAPAPK MGYG000000133_01634;MGYG000001365_01216;MGYG000001577_01926;MGYG000000053_01133;MGYG000003926_00723 domain d__Bacteria 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,22UXN@171550|Rikenellaceae 0.4 186801|Clostridia 0.4 J 0.6 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 0.6 infB 0.6 - 1.0 - 0.8 ko:K02519 0.6 - 0.8 - 1.0 - 0.8 - 0.8 ko00000,ko03012,ko03029 0.6 - 0.8 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 0.6 - 1.0 - 1.0 - 1.0 GT2 0.6 - - - - 0.8 0.8 0.8 0.8 0.8 none 1.0 0 49091 0 0 0 0 0 0 0 0 0 0 0 49863 0 0 0 0 0 60061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53599 267385 185006 221950 124332 323546 186387 299598 419702 255476 192032 723909 296529 317674 114077 101682 263045 267909 0 286797 142190 172758 154878 0 115297 196840 248034 269499 0 266430 0 337808 226854 210979 73286 306667 73197 142691 297502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88789 59375 0 94825 0 0 0 0 39631 83554 0 0 0 106918 0 0 53987 0 0 0 0 0 0 52854 116793 0 0 0 0 0 65606 0 0 69355 55162 10970080 10643197 12960950 12907123 4140507 8086282 17275590 9361085 8490178 11104301 12473277 14516065 4745057 16594845 10112355 5006881 7514590 6563496 5295563 4961520 20551395 6097035 4951176 8873174 8379798 8221942 12913066 2548567 13760939 3491259 9483563 6479787 20225703 7715670 16829591 9985680 7375590 9984787 -AAPAPVAAPK MGYG000002494_03382 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1RHH7@1224|Proteobacteria,1RNAT@1236|Gammaproteobacteria,3WY36@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 PTS system sorbose subfamily IIB component 1.0 manX 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0008645,GO:0008982,GO:0009401,GO:0009987,GO:0015144,GO:0015145,GO:0015149,GO:0015578,GO:0015749,GO:0015761,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0022870,GO:0031224,GO:0031226,GO:0034219,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046323,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098657,GO:0098704,GO:0098708,GO:0098739,GO:1904659 1.0 2.7.1.191 1.0 ko:K02793,ko:K02794 1.0 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 1.0 M00276 1.0 R02630 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.6.1 1.0 - 1.0 iAPECO1_1312.APECO1_874,iECOK1_1307.ECOK1_1934,iECS88_1305.ECS88_1869,iPC815.YPO1758,iUMN146_1321.UM146_08085,iUTI89_1310.UTI89_C2014 1.0 EIIA-man,PTSIIB_sorb 1.0 - 1.0 - 1.0 - 1.0 - 1.0 protein-N(pi)-phosphohistidine--D-mannose phosphotransferase. mannose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-mannose(out) + N(pros)-phospho-L-histidyl-[protein] = D-mannose 6-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Phosphotransferase system (PTS);Metabolic pathways;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1922204 0 0 0 0 3923194 2168039 0 2049663 0 0 0 0 0 0 0 0 0 2926765 0 0 4729629 0 3516597 0 1374628 0 0 3123279 0 0 0 0 0 0 0 2052137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAQIK MGYG000001711_01335 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__Holdemanella|s__Holdemanella biformis|m__MGYG000001711 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,3VNYH@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 937508 0 0 0 0 0 0 0 0 0 1004929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 653050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104456 0 0 0 0 0 0 0 0 0 259285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAQTEQTTEAAVVEEGGGLHK MGYG000004797_01477 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 448943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1291117 0 0 0 0 0 0 0 0 0 0 0 0 0 5801260 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2890886 0 0 0 0 0 0 0 0 0 0 0 0 0 4064637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7779289 0 0 0 0 0 0 0 0 0 0 0 0 0 4323978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1769547 0 0 0 0 0 0 0 0 0 0 0 0 0 602041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPATEGQFGDDITMASWK MGYG000002517_01844 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1143@1|root,COG4624@1|root,COG1143@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Iron only hydrogenase large subunit, C-terminal domain 1.0 - 1.0 - 1.0 1.12.7.2 1.0 ko:K00533 1.0 - 1.0 - 1.0 R00019 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe_hyd_lg_C,Fer4,Fer4_6,Fer4_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ferredoxin hydrogenase. uptake hydrogenase. Can use molecular hydrogen for the reduction of a variety of substances.-!-Formerly EC 1.12.1.1, EC 1.12.7.1, EC 1.18.3.1, EC 1.18.99.1 and EC 1.98.1.1. H2 + 2 oxidized [2Fe-2S]-[ferredoxin] = 2 H(+) + 2 reduced [2Fe-2S]- [ferredoxin]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1100462 1221955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPAVATK MGYG000001300_02529 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG3940@1|root,COG3940@2|Bacteria,1VAX9@1239|Firmicutes,24NY2@186801|Clostridia,3WKE6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Ricin-type beta-trefoil 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 RicinB_lectin_2 1.0 - 1.0 CBM13 1.0 CBM13 1.0 CBM13 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 119658 0 0 0 0 0 87590 0 0 0 0 0 0 0 0 0 0 0 301502 1015657 0 0 0 0 0 242147 0 0 0 0 0 0 0 0 0 0 67381 0 505043 0 0 0 0 0 1285598 0 0 0 0 0 0 0 0 0 0 0 1114687 539063 0 0 0 0 0 643717 0 0 0 0 0 0 0 0 0 0 559585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84396 0 0 0 0 0 0 0 0 0 0 82144 0 0 0 0 0 0 0 303151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPDNMK MGYG000002492_01331;MGYG000000262_01692 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111944 0 0 0 0 0 0 0 346165 0 0 0 0 0 0 0 393300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 839999 0 0 0 0 481684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPDNMKVADTK MGYG000000262_01692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 514580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 868223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPDQPK MGYG000002469_01094;MGYG000001292_01123 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Belongs to the transketolase family 1.0 tkt 1.0 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA,Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133041 0 0 0 0 122248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPEITR MGYG000002477_01229;MGYG000002494_02707;MGYG000002534_04377;MGYG000000235_02908 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,3WVEI@544|Citrobacter 0.75 1236|Gammaproteobacteria 1.0 O 1.0 HflC and HflK could encode or regulate a protease 1.0 hflK 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 1.0 - 1.0 ko:K04088 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Band_7,HflK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 164049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 938991 0 0 648339 0 0 0 0 0 0 0 0 0 0 0 0 0 899427 0 0 0 0 0 0 0 0 0 0 0 0 483583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPELM(Oxidation)PTAEQR MGYG000004271_02489;MGYG000000271_01599 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Radical SAM domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,Radical_SAM,SPASM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPELMPTAEQR MGYG000004271_02489;MGYG000000271_01599 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Radical SAM domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,Radical_SAM,SPASM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPGAAAGGAAAEEK MGYG000004704_00527 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__|m__MGYG000004704 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,4PR0T@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1337463 0 0 0 0 0 -AAPGLTGFTK MGYG000001300_00048;MGYG000001761_00345;MGYG000002272_01119;MGYG000003937_02082;MGYG000004679_00432;MGYG000000022_01588;MGYG000003899_01912;MGYG000002040_02064;MGYG000004700_00143;MGYG000000084_00427;MGYG000003921_00872;MGYG000004866_00913;MGYG000001255_01742 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3WGDG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 Branched-chain amino acid aminotransferase 1.0 ilvE 1.0 - 1.0 2.6.1.42,4.1.3.38 1.0 ko:K00826,ko:K02619 1.0 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R05553,R10991 1.0 RC00006,RC00036,RC01843,RC02148 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 branched-chain-amino-acid transaminase. | aminodeoxychorismate lyase. transaminase B. | enzyme X. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. | Forms part of the folate biosynthesis pathway.-!-Acts on 4-amino-4-deoxychorismate, the product of EC 2.6.1.85, to form p-aminobenzoate. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. | 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Valine, leucine and isoleucine degradation;Cysteine and methionine metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Folate biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 1239270 0 0 2084247 2670132 0 0 0 0 0 0 4674808 2250194 0 0 0 4051657 0 0 0 0 4405135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 901497 0 0 0 0 0 0 0 0 0 0 0 793184 0 0 0 0 0 0 0 0 4087885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2264884 0 0 1640904 1969860 0 0 0 0 0 0 0 1687460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5927277 771522 0 0 0 6844261 0 0 0 0 6133136 0 0 0 0 0 0 0 0 0 0 -AAPGYYMAK MGYG000001300_01368;MGYG000000022_00954;MGYG000002040_00422;MGYG000003899_01851;MGYG000004679_00269 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WHEI@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties 1.0 glgP 1.0 - 1.0 2.4.1.1 1.0 ko:K00688 1.0 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 1.0 - 1.0 R02111 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GT35 1.0 - 1.0 DUF3417,Phosphorylase 1.0 2.4.1.1 1.0 GT35 1.0 GT35 1.0 GT35 1.0 glycogen phosphorylase. polyphosphorylase. This entry covers several enzymes from different sources that act in vivo on different forms of (1->4)-alpha-D-glucans.-!-Some of these enzymes catalyze the first step in the degradation of large branched glycan polymers - the phosphorolytic cleavage of alpha-1,4-glucosidic bonds from the non-reducing ends of linear poly(1->4)-alpha-D-glucosyl chains within the polymers.-!-The enzyme stops when it reaches the fourth residue away from an alpha-1,6 branching point, leaving a highly branched core known as a limit dextrin.-!-The description (accepted name) of the enzyme should be modified for each specific instance by substituting 'glycogen' with the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, etc. [(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. 1.0 1.0 1.0 1.0 Necroptosis;Biofilm formation - Escherichia coli;Metabolic pathways;Starch and sucrose metabolism;Insulin resistance;Glucagon signaling pathway;Biosynthesis of secondary metabolites;Insulin signaling pathway 1.0 none 1.0 1064097 0 1025925 1014079 0 891870 642033 0 652495 0 0 0 0 0 0 0 0 1659200 905350 0 0 758946 1100093 648980 0 743910 0 1788433 0 0 0 0 858737 0 0 0 714367 1019221 1158387 0 913274 1657852 0 848758 1448265 0 1216323 0 0 0 0 0 0 0 0 1086245 1495190 0 0 574535 1655758 694361 0 1020127 0 1436341 0 0 0 0 967509 0 0 0 990439 893641 565959 0 328405 190883 0 306406 401587 0 501939 0 0 0 0 0 0 0 0 934313 318626 0 0 276060 946003 373226 0 348323 0 975252 0 0 0 0 319632 0 0 0 452628 0 527897 0 467989 476873 0 737132 528426 0 580408 0 0 0 0 0 0 0 0 381967 514612 0 0 849484 266685 662398 0 560813 0 353507 0 0 0 0 641725 0 0 0 329230 755556 258141 0 226046 201956 0 0 290819 0 0 0 0 0 0 0 0 0 0 797897 229408 0 0 138071 1095810 372967 0 0 0 1054777 0 0 0 0 220669 0 0 0 0 154678 -AAPHGTGHIK MGYG000000133_00291;MGYG000002492_02170;MGYG000000489_00852;MGYG000001338_00230 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3XZFI@572511|Blautia 0.5 186801|Clostridia 1.0 EH 0.5 Psort location Cytoplasmic, score 8.87 0.5 ilvE 1.0 - 1.0 2.6.1.42,4.1.3.38 1.0 ko:K00826,ko:K02619 1.0 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R05553,R10991 1.0 RC00006,RC00036,RC01843,RC02148 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 branched-chain-amino-acid transaminase. | aminodeoxychorismate lyase. transaminase B. | enzyme X. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. | Forms part of the folate biosynthesis pathway.-!-Acts on 4-amino-4-deoxychorismate, the product of EC 2.6.1.85, to form p-aminobenzoate. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. | 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Valine, leucine and isoleucine degradation;Cysteine and methionine metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Folate biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147915 0 0 0 0 64712 0 0 0 0 13985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190483 0 0 0 0 365601 0 0 0 0 46317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75531 0 0 0 0 0 10019 0 0 0 0 226477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11969 0 0 0 0 80141 0 0 0 0 24436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246696 43312 0 0 0 0 21453 0 0 0 0 172221 0 0 0 0 0 0 0 0 0 0 -AAPHGTGIYK MGYG000001337_04196;MGYG000000013_03135;MGYG000000196_04103;MGYG000001345_01382;MGYG000001378_03184 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,2FMPE@200643|Bacteroidia,4AMTS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase 1.0 ilvE 1.0 - 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways;Cysteine and methionine metabolism;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 668074 0 0 661893 0 450385 0 0 0 0 892852 0 0 0 0 0 0 0 0 0 0 421177 0 811686 0 573218 0 0 0 0 0 0 0 712244 0 0 445868 0 543894 0 0 801107 0 727329 0 0 0 0 1147300 0 0 0 0 0 0 0 0 0 0 748945 0 576778 0 425081 0 0 0 0 0 0 0 460768 0 0 890870 0 268611 0 0 227783 0 143622 0 0 0 0 485869 0 0 0 0 0 0 0 0 0 0 187775 0 472942 0 370214 0 0 0 0 0 0 0 366156 0 0 112044 0 592601 0 0 414784 0 520286 0 0 0 0 798692 0 0 0 0 0 0 0 0 0 0 456949 0 0 0 484361 0 0 0 0 0 0 0 620536 0 0 637956 0 561999 0 0 231270 0 342146 0 0 0 0 848155 0 0 0 0 0 0 0 0 0 0 583001 0 985783 0 710058 0 0 0 0 0 0 0 586644 0 0 428268 0 -AAPHGTGNIK MGYG000001319_00809 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,4BWI7@830|Butyrivibrio 1.0 186801|Clostridia 1.0 EH 1.0 Amino-transferase class IV 1.0 ilvE 1.0 - 1.0 2.6.1.42,4.1.3.38 1.0 ko:K00826,ko:K02619 1.0 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R05553,R10991 1.0 RC00006,RC00036,RC01843,RC02148 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 branched-chain-amino-acid transaminase. | aminodeoxychorismate lyase. transaminase B. | enzyme X. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. | Forms part of the folate biosynthesis pathway.-!-Acts on 4-amino-4-deoxychorismate, the product of EC 2.6.1.85, to form p-aminobenzoate. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. | 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Valine, leucine and isoleucine degradation;Cysteine and methionine metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Folate biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 714230 0 0 0 0 859444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99092 0 0 0 0 62706 0 0 0 0 249606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114142 0 0 0 0 272363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 58533 0 0 0 0 0 0 0 0 0 254112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 126305 0 0 0 0 0 0 0 0 0 0 -AAPHLDG(Gly->Ser)SYAAFGK MGYG000000133_02803;MGYG000000301_01800 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides 1.0 ppiB 1.0 - 1.0 5.2.1.8 1.0 ko:K03768 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Pro_isomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPHLDGAYAAFGK MGYG000003335_00657;MGYG000000251_00957 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia 0.5 186801|Clostridia 1.0 O 1.0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides 1.0 ppiB 1.0 - 1.0 5.2.1.8 1.0 ko:K03768 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Pro_isomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 413782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPHLDGEYAAFGK MGYG000000077_01045;MGYG000000262_01678 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,25W2U@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 O 1.0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides 1.0 ppiB 1.0 - 1.0 5.2.1.8 1.0 ko:K03768 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Pro_isomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 79157 0 230985 0 0 0 0 0 0 0 0 0 0 279579 0 0 0 0 442217 0 300666 240501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213177 0 256651 0 0 0 0 0 0 0 0 0 0 309949 0 0 0 0 326931 0 381855 307408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 840245 0 868148 0 0 0 0 0 0 0 0 0 0 420704 0 0 0 0 732554 0 836225 739416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 560843 0 467384 0 0 0 0 0 0 0 0 0 0 562386 0 0 0 0 425898 0 126916 339982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 96079 0 326321 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471215 0 343537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPHLDGQYAAFGK MGYG000000028_00332;MGYG000002528_01778 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,268D2@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 O 1.0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides 1.0 ppiB 1.0 - 1.0 5.2.1.8 1.0 ko:K03768 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Pro_isomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 0 199010 0 0 0 196988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230599 0 0 0 0 0 97381 233390 0 0 0 0 0 0 0 0 0 0 1137978 0 0 0 703719 0 0 0 0 0 0 0 0 0 0 0 484928 141766 0 0 758559 519747 975684 0 0 0 500046 266693 0 0 439453 0 0 0 0 0 0 0 2932127 0 0 0 1411967 0 0 0 0 0 0 0 0 0 0 0 219860 1006685 0 0 3797541 527347 1249991 0 0 0 850482 2429317 0 0 3261207 0 0 0 0 0 0 0 703850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1009113 0 0 841791 0 0 0 0 0 0 0 1554182 0 0 0 1471507 0 0 0 0 0 0 0 0 0 0 0 0 642911 0 0 781108 0 1832870 0 0 0 0 1334307 0 0 0 0 0 0 0 0 0 -AAPHLDGSYAAFGK MGYG000000133_02803;MGYG000000301_01800 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides 1.0 ppiB 1.0 - 1.0 5.2.1.8 1.0 ko:K03768 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Pro_isomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 1.0 none 1.0 591045 316695 384479 181515 0 666840 279709 506967 469507 502020 629524 378966 932838 801629 665212 424183 387522 0 613641 0 350637 434431 0 534646 385155 761029 571828 0 888774 0 585582 544711 343087 715487 459767 634570 158498 536486 507925 327182 126089 69131 0 154200 477333 340427 215532 432656 199402 0 247316 0 85652 0 0 0 86911 0 195114 80896 0 163467 321458 212755 0 0 481015 0 150594 220655 278029 73444 233826 0 84564 244546 569486 330184 370234 305721 0 560133 147422 460145 307142 439613 242356 361901 289066 299743 428878 369718 323099 0 423816 0 269268 598872 0 0 493278 415398 416674 0 405383 0 441439 452979 456553 311283 452103 303000 437260 256702 108312 0 433659 0 0 0 332505 0 101030 368938 0 0 74535 0 0 0 0 0 136012 0 0 0 0 0 0 0 262025 0 576858 0 85338 0 0 0 0 0 0 0 2421596 2728622 3294267 4427968 0 1914749 3994029 2193843 1979937 3551036 3448707 2642897 3290369 3872496 2272507 2199051 2787927 0 2857002 0 3561200 2434955 0 3261867 2996106 2555886 2776381 0 3995621 0 2220366 3999061 4240984 2543751 1660642 2263324 1827283 1856461 -AAPIKPEVSFDDFEKLDIR MGYG000003697_01572;MGYG000002834_00477 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,2FNV6@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation 1.0 metG 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.10 1.0 ko:K01874 1.0 ko00450,ko00970,map00450,map00970 1.0 M00359,M00360 1.0 R03659,R04773 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,tRNA-synt_1g,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methionine--tRNA ligase. MetRS. In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9. ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis;Selenocompound metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71190 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 491858 0 0 269998 0 0 0 0 0 0 0 0 0 0 0 343428 0 0 0 382223 593378 347374 0 0 0 263994 0 0 0 0 292745 0 0 0 0 268241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPILLEPIMK MGYG000000050_01748;MGYG000004501_01155;MGYG000000201_03874 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 0.6666666666666666 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 520371 0 0 0 0 0 0 0 0 0 0 0 146052 0 0 0 539005 94195 225832 0 0 0 0 0 0 0 0 0 0 0 0 0 357500 0 0 141867 0 0 212720 0 0 0 0 0 0 0 0 0 0 0 815317 0 0 0 0 298097 530316 0 0 0 502776 0 0 934718 0 92931 0 0 0 0 410229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107063 0 170844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105057 0 0 0 0 0 87251 0 0 0 115452 0 0 0 0 0 0 0 0 0 0 0 0 765000 0 0 895719 0 0 0 0 0 0 0 0 0 0 0 208386 0 0 0 1486973 511218 998424 0 0 0 736553 0 0 484385 0 1368425 0 0 0 0 698283 -AAPILLEPIMR MGYG000000171_02843;MGYG000004733_01212 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPILLEPIMR(Arg->Lys) MGYG000000171_02843;MGYG000004733_01212 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPIYENGTPEQK MGYG000000084_00625;MGYG000002619_02237;MGYG000001300_00293;MGYG000004732_01390;MGYG000001255_01112;MGYG000002040_01717 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WI1F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 1444059 763405 2169331 1847161 686322 1713453 1477043 1056434 2117547 1342467 1701261 1537255 1265897 2139833 1297205 1226564 0 1012158 2720493 1968990 0 1405866 986311 1665344 1542051 1865507 1733362 896211 0 1512823 1635071 826079 1515623 2890445 0 1414269 1465233 2135939 1316081 1785205 2265605 1135024 1193882 1648489 1548345 979253 1776496 443282 2082391 2126299 1253833 1363339 1140958 1210786 0 1385174 2043952 1213128 0 964620 1962134 1003013 1753886 1199790 1112888 1373053 0 1398405 1386622 1944925 1953268 1194515 0 1126898 884906 1382869 614345 1031278 1661717 844179 1899234 1201577 1225767 682452 1521792 534336 1887273 1197807 940717 1324846 699676 1302493 0 1912163 788368 736998 0 817688 1486351 1452724 791678 714639 538615 1088582 0 1310847 1652416 703975 860188 805699 0 1176793 807019 1361227 1145883 1543710 2666577 1609161 2434159 1801367 3310167 1081043 2027068 1578160 1495179 2057076 1415448 1514698 1441072 1071099 0 2362518 2254536 1555229 0 1714508 1424869 1841034 2079816 1762509 1495417 2512490 0 1515789 2224794 1671753 1945914 1744139 0 1454250 1059127 2600413 0 0 165270 0 0 0 0 0 0 0 0 0 119779 0 0 0 0 521994 0 255511 0 0 600790 94924 0 0 0 740171 0 0 0 0 377812 0 0 0 125277 386862 -AAPKPIVRPEVSDEEVSK MGYG000000074_02676 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,22UXN@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1069684 0 0 0 0 0 0 0 0 -AAPKSEEK MGYG000001637_00284 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp900543445|m__MGYG000001637 1.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 213405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 932311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507389 0 0 0 0 676660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340177 0 0 0 0 532529 -AAPLGTGIYK MGYG000001661_02539;MGYG000001313_02992 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,2FMPE@200643|Bacteroidia,4AMTS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase 1.0 ilvE 1.0 - 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways;Cysteine and methionine metabolism;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470368 0 0 0 0 472954 0 0 0 0 399280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2382296 0 0 0 0 1802446 0 0 0 0 1939537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321255 0 0 0 0 0 0 0 0 0 174788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1348453 0 0 0 0 1144416 0 0 0 0 835624 0 0 0 0 0 0 0 0 0 0 -AAPLGTGTFK MGYG000001306_01027;MGYG000001599_02056;MGYG000003693_03058;MGYG000001364_00192 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,2FMPE@200643|Bacteroidia,4AMTS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase 1.0 ilvE 1.0 - 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways;Cysteine and methionine metabolism;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2485263 0 0 0 0 3412574 0 0 0 0 3025992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534482 0 0 0 0 318061 0 0 0 0 402174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPNALYLIVSNPVDIMTYVFTK MGYG000001338_01861 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3XZ3D@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 ldh 1.0 - 1.0 1.1.1.27 1.0 ko:K00016 1.0 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 1.0 - 1.0 R00703,R01000,R03104 1.0 RC00031,RC00044 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Ldh_1_C,Ldh_1_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-lactate dehydrogenase. L-lactic dehydrogenase. Also oxidizes other (S)-2-hydroxymonocarboxylic acids.-!-NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme. (S)-lactate + NAD(+) = H(+) + NADH + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Cysteine and methionine metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Glucagon signaling pathway;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2250085 0 482004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83956 0 0 0 0 0 0 0 1797745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3238843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2515564 0 0 0 0 0 -AAPNGTGHIK MGYG000001652_01374;MGYG000000193_03518 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,27INK@186928|unclassified Lachnospiraceae 0.5 186801|Clostridia 1.0 EH 1.0 Amino-transferase class IV 1.0 ilvE 1.0 - 1.0 2.6.1.42,4.1.3.38 1.0 ko:K00826,ko:K02619 1.0 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R05553,R10991 1.0 RC00006,RC00036,RC01843,RC02148 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 branched-chain-amino-acid transaminase. | aminodeoxychorismate lyase. transaminase B. | enzyme X. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. | Forms part of the folate biosynthesis pathway.-!-Acts on 4-amino-4-deoxychorismate, the product of EC 2.6.1.85, to form p-aminobenzoate. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. | 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Valine, leucine and isoleucine degradation;Cysteine and methionine metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Folate biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 647239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPNLPEIR MGYG000003697_02941 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1435@1|root,COG1435@2|Bacteria,4NFWU@976|Bacteroidetes,2FNY3@200643|Bacteroidia,4APFH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527553 0 898397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610101 0 0 0 0 703025 0 0 0 0 134835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPNTIPTAAK MGYG000002534_04862;MGYG000002385_03572;MGYG000002515_03619;MGYG000002477_00691;MGYG000002494_01536 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,3XMH2@561|Escherichia 0.8 1236|Gammaproteobacteria 1.0 E 1.0 Acts on leucine, isoleucine and valine 0.8 ilvE 1.0 GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 iB21_1397.B21_03597,iECBD_1354.ECBD_4269,iECB_1328.ECB_03648,iECD_1391.ECD_03648,iECO103_1326.ECO103_4394 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways;Cysteine and methionine metabolism;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 397689 0 0 0 0 0 0 253769 0 115101 0 0 0 0 188371 0 0 0 0 0 0 0 344513 0 0 0 0 172581 0 0 336994 0 0 0 0 428237 0 0 3068364 0 0 0 0 0 0 1943073 0 808335 0 0 0 0 3935241 0 0 0 0 0 0 0 2423326 0 0 0 0 3321351 0 0 3107485 0 0 0 0 2285853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541820 0 0 0 0 0 0 478450 0 0 0 0 0 0 0 300539 0 0 0 0 218707 0 0 0 0 0 0 0 292496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPPPPPAPKPEVATK MGYG000002834_01606;MGYG000003697_01975;MGYG000002293_00416 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,2FNG9@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 COG0226 ABC-type phosphate transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K02040 1.0 ko02010,ko02020,ko05152,map02010,map02020,map05152 1.0 M00222 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.7 1.0 - 1.0 - 1.0 PBP_like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Tuberculosis;ABC transporters;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3435002 0 0 2985217 0 0 0 0 2876259 0 0 0 0 0 0 2944886 0 0 0 2867485 1094501 3439962 0 0 0 4162999 0 0 0 1471630 2137841 0 0 0 0 3311304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPSGASTGSR MGYG000002506_02347;MGYG000000093_02751;MGYG000001692_04471 order d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales 1.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,3XNNK@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 0.6666666666666666 F 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 0.6666666666666666 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 iPC815.YPO3376 0.6666666666666666 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Methane metabolism;Carbon metabolism;RNA degradation;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Biosynthesis of amino acids 1.0 none 1.0 97219 0 201443 0 137431 569052 169602 255767 282365 289536 176841 0 0 0 351527 0 116475 0 396805 0 244395 523659 0 479669 292147 321549 0 0 203492 208881 0 168922 78809 489028 417820 0 174702 360555 179572 112813 159254 0 175850 236603 242955 268688 290635 199609 87151 0 0 0 164835 52663 293514 0 612989 0 163011 91580 0 0 194615 77326 0 0 50595 56136 0 186511 138002 119717 208428 169144 118697 140376 94686 138450 328840 0 134837 443656 126782 124446 228642 230106 65064 0 0 0 295658 261742 68329 0 97373 0 258238 396732 0 555199 337999 0 0 0 103008 38004 0 0 234492 225645 189297 222777 170728 254956 2424666 2712867 2263243 0 1502669 2883081 7377318 1856563 2663013 2574325 1130813 0 0 0 700388 2272225 3005654 0 1718267 0 1257304 5840114 0 3137658 1803981 1653363 0 0 3095267 2009989 0 1324125 1408703 1629587 3218923 1033191 1918087 3681128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPSMSHNVSIQGTSGK MGYG000001346_02330 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546651 0 0 0 0 0 0 0 605244 940183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 602853 638704 0 493999 0 0 596856 0 0 0 0 0 0 0 0 0 0 0 141834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 445546 0 0 0 0 0 0 0 0 323167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPSNIK MGYG000002517_00959;MGYG000000076_02414 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 137252 54718 93059 0 0 0 0 183688 118170 0 0 0 0 82574 123293 0 83490 0 0 69534 70656 0 0 0 41161 80305 0 0 0 0 0 0 57748 0 0 93129 44722 384135 0 119076 0 0 0 0 0 170946 0 0 0 0 0 0 0 0 0 0 0 0 47968 0 0 0 0 0 0 0 0 0 0 0 27550 0 0 0 0 0 374719 185850 74312 0 0 0 0 160111 74439 0 0 0 0 150011 201214 0 452652 0 0 161686 317402 0 0 0 272286 527809 0 0 0 0 0 0 161188 0 0 175130 141219 0 132206 0 0 0 0 0 0 346665 693576 0 0 0 0 599781 456865 0 42552 0 0 358788 869559 0 0 0 458206 251352 0 0 0 0 0 0 56117 0 0 614307 347883 103171 1116660 2269492 423268 0 0 0 0 1315076 453256 0 0 0 0 955957 911343 0 1857927 0 0 1688649 3204883 0 0 0 273689 576526 0 0 0 0 0 0 883979 0 0 809979 938551 255494 -AAPSTVK MGYG000002291_02265 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__OM05-12|s__OM05-12 sp003438995|m__MGYG000002291 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 68210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1159350 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 578910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPSYEELSNSQELLETGIK MGYG000002323_04215;MGYG000000093_05344;MGYG000002515_03903;MGYG000002506_03402;MGYG000002494_02404;MGYG000002366_00010;MGYG000002507_04224 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,3XPEM@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 821486 752905 885288 927220 510061 1452718 1121096 848870 910840 1155326 356153 809311 0 971427 696870 300394 985521 0 746987 703158 619743 982846 0 1008678 846754 786381 879606 0 1232995 962536 701750 974048 609870 838286 784518 836816 695207 726993 2215786 3754486 4102252 2602745 3615153 6321430 3304497 2502519 2539304 4506558 1233497 2682556 2633140 0 2656674 2959522 5219642 0 4026673 2194101 4079202 8081576 0 6214515 4543983 3019840 2656033 0 5527443 5093620 2164389 3284546 3884824 2123288 2116860 2366443 2172130 2413783 1101003 1139562 1230954 1234446 1246379 2543860 1473807 1202572 1579615 1239585 799376 1006946 830513 1020602 965095 861437 613689 0 920776 1215918 947521 1869302 0 1817767 1240487 1180337 1199304 0 1160850 1132959 888458 1043753 1176305 1384778 1300140 1350369 1080100 1181753 1747729 1022751 1320755 1035931 1104123 2224023 1980587 1663837 1328631 2018351 816985 834381 1094937 1179704 1120464 1152133 1565785 0 1237418 1403890 1694156 2950553 0 1911865 2177224 1530064 1719942 0 1660102 1385025 710130 1000692 1238177 2054024 1685465 1716941 1112833 1234400 0 189105 141570 0 0 0 0 0 0 0 152046 0 194488 230225 0 0 0 0 0 0 0 0 0 88831 0 93136 0 0 0 0 0 0 0 0 0 0 234101 235032 -AAPVDMTLVDAK MGYG000002720_00480 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,36EA6@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 - 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_10,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1153556 0 0 0 0 0 0 0 1905528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 625784 0 0 0 0 0 0 0 479302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPVILEPIMK MGYG000000154_02190;MGYG000001338_03374 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1370652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPVKWDHNVVYNSK MGYG000004271_00865 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate 1.0 argJ 1.0 - 1.0 2.3.1.1,2.3.1.35 1.0 ko:K00620 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028 1.0 R00259,R02282 1.0 RC00004,RC00064 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ArgJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 amino-acid N-acetyltransferase. | glutamate N-acetyltransferase. N-acetylglutamate synthase. | ornithine transacetylase. Also acts with L-aspartate and, more slowly, with some other amino acids. | Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity. acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate. | L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L- glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPVLLEPIM(Oxidation)K MGYG000001637_00070;MGYG000000154_02190;MGYG000004414_01432;MGYG000000417_00151;MGYG000001338_03374;MGYG000000263_00835;MGYG000000142_00172;MGYG000002312_02892;MGYG000000200_01983;MGYG000000216_02407;MGYG000002492_00343;MGYG000001186_01601;MGYG000001607_01044;MGYG000000206_00900 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 0.9285714285714286 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 619139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPVLLEPIMK MGYG000001637_00070;MGYG000000154_02190;MGYG000004414_01432;MGYG000000417_00151;MGYG000001338_03374;MGYG000000263_00835;MGYG000000142_00172;MGYG000002312_02892;MGYG000000200_01983;MGYG000000216_02407;MGYG000002492_00343;MGYG000001186_01601;MGYG000001607_01044;MGYG000000206_00900 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 0.9285714285714286 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 868775 2221432 987322 678704 1478942 722070 413933 924740 675703 983545 2309665 1007500 1210412 582581 896643 919985 972645 2588249 796546 907401 966209 753552 2498758 269713 1039789 485822 730115 2954500 965949 638255 767848 1528879 747150 742114 698347 699938 566859 875897 1375360 6201744 1419703 1666482 2487657 884865 1661442 1746585 799309 1001107 1856931 836858 2190830 1035213 960546 1449303 762601 9667013 963214 1691331 1018397 519393 4682865 1531382 1001335 1396890 1521234 7977124 1209807 999638 6264058 2303579 1534265 1485082 1272885 1850880 1109041 1753386 2094178 2588044 3771225 1275669 992630 905595 1539247 1533664 1197119 1439369 1937863 2114235 2163776 1589652 1982033 3318847 1517480 1759546 1418270 1437975 1379473 2002747 3322137 839990 1776978 1557935 1994937 3878553 1154461 1962149 1345703 3167281 5581288 2014510 2129728 1025019 1863901 4656750 561099 3641336 1448931 591854 1848823 839445 705816 453126 559746 657319 1444534 635365 1207293 572137 351366 1145722 768589 2144461 297230 549156 414970 994901 1450502 0 401083 297941 520043 2663895 1005822 582792 3692504 2189588 1406268 0 512888 396152 415978 1799912 326247 3976989 1231897 149155 241723 97645 366098 569248 294985 236948 609817 432620 172132 507286 336904 1202500 168528 777463 214391 293305 230392 389707 1616773 162841 302724 257278 297860 2171986 320645 197353 1971419 2308239 1841003 320499 292402 293172 102978 873918 -AAPVSHIWYFK MGYG000001514_00034;MGYG000002528_01102;MGYG000001642_00113;MGYG000000142_00116;MGYG000003266_00420;MGYG000000501_01311;MGYG000003825_00451;MGYG000002445_01330;MGYG000000146_01134;MGYG000000231_01252;MGYG000000022_02279;MGYG000000245_03244;MGYG000000333_00801;MGYG000000258_01856;MGYG000000989_00162;MGYG000004869_02970;MGYG000001470_03728;MGYG000000164_01117;MGYG000004717_01316;MGYG000000198_01126;MGYG000000271_03640;MGYG000001707_01472;MGYG000000193_02078;MGYG000002517_00198;MGYG000002105_00006;MGYG000000217_01476;MGYG000000262_00026;MGYG000002992_02046;MGYG000002961_00370;MGYG000001714_01233;MGYG000001683_01329;MGYG000003239_00840;MGYG000001338_03383;MGYG000003116_00422;MGYG000000233_00816;MGYG000002074_00230;MGYG000000036_00944;MGYG000000291_00760;MGYG000000002_03603;MGYG000000127_00619;MGYG000000118_01190;MGYG000000417_00095;MGYG000003782.1_00607;MGYG000001424_01001;MGYG000001315_01195;MGYG000004285_00601;MGYG000001300_00284;MGYG000001756_02184;MGYG000002315_00750;MGYG000004681_00046;MGYG000002279_01918;MGYG000000188_00926;MGYG000000249_00041;MGYG000004884_01728;MGYG000002968_00677;MGYG000004630_01089;MGYG000001627_01519;MGYG000000255_01999;MGYG000003391_00537;MGYG000001493_02697;MGYG000003684_05128;MGYG000002775_00054;MGYG000002298_02601;MGYG000000312_01432;MGYG000000084_01993;MGYG000000251_01868;MGYG000001255_01103;MGYG000000371_01545;MGYG000000133_02999;MGYG000001615_01701;MGYG000004221_01655;MGYG000000179_00949;MGYG000002286_02465;MGYG000002106_00979;MGYG000004769_00421;MGYG000003122_00562;MGYG000002492_00340;MGYG000000184_00998;MGYG000000429_01277;MGYG000000802_00744;MGYG000001319_01768;MGYG000002052_00236;MGYG000000404_00524;MGYG000002919_00394;MGYG000001617_00231 domain d__Bacteria 1.0 COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CUED@84998|Coriobacteriia 0.16470588235294117 186801|Clostridia 0.7764705882352941 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 0.9647058823529412 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 0.8352941176470589 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 1125679 1234971 791054 556134 1158592 880872 0 1555226 0 0 1289905 0 0 0 926746 0 649936 1754657 1008868 0 1209411 1068612 248242 255309 1239636 0 975985 0 617852 1122766 931616 1020061 819496 0 1000305 1058565 921859 798366 119252 116277 59651 102101 145133 0 0 253132 0 0 52598 0 104143 0 138601 0 0 1238987 160407 276095 318550 371136 975485 150463 219085 168626 162796 1016572 215364 116978 226478 0 0 0 155724 249228 76530 0 338070 158687 301428 266460 109580 215669 0 339560 0 0 157979 0 231709 0 432474 286877 0 214951 467007 474440 256919 271855 264256 208914 233389 260371 455518 230492 350965 339847 0 289685 433021 0 418561 72160 137380 334041 733361 585538 450986 488171 649669 422663 0 535474 0 0 416737 0 632929 0 473381 856344 420050 204961 424497 702354 621448 677843 0 252623 469861 350260 651550 454561 568639 586729 637035 531806 586414 0 580811 420532 532778 232420 100017 67921 74798 184771 73834 292697 0 71859 0 0 0 0 0 0 0 102644 96400 155880 105285 0 81592 102040 274092 0 0 66894 0 175930 0 0 69074 52890 72115 0 0 164007 275261 82440 -AAPVTHIWFFK MGYG000001292_02175 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CZ1D@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 499630 0 0 0 0 132443 0 0 0 0 356996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPVVPN(Deamidated)GPAK MGYG000003697_01611 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,2FSK4@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 Preprotein translocase SecG subunit 1.0 secG 1.0 - 1.0 - 1.0 ko:K03075 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2 1.0 - 1.0 - 1.0 SecG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPVVPTSPAK MGYG000002293_00368 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,2FSK4@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 Preprotein translocase SecG subunit 1.0 secG 1.0 - 1.0 - 1.0 ko:K03075 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2 1.0 - 1.0 - 1.0 SecG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1322197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1168029 0 0 0 0 1249397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAPYGTGR MGYG000002171_02681;MGYG000000243_02172;MGYG000002478_00294 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,2FMPE@200643|Bacteroidia,4AMTS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase 1.0 ilvE 1.0 - 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Valine, leucine and isoleucine degradation;Metabolic pathways;Cysteine and methionine metabolism;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 4516852 0 3069845 2015573 7090623 0 0 1729708 0 2194669 3768523 5642408 7440498 3149501 2075648 2610108 2185751 0 0 1894223 2676027 6225557 6850753 0 0 3029407 0 7525515 0 0 4457881 8322683 0 0 0 4171330 0 0 1253316 0 1880919 2008390 1918775 0 0 3481002 0 2148664 3038645 1743719 2308863 3290692 1528166 928635 2483197 0 0 1585386 2231945 1451956 1951071 0 0 2081390 0 1989398 0 0 1704128 2312460 0 0 0 1557148 0 0 1911284 0 1463429 1353991 1702666 0 0 1423193 0 2405351 1618447 1471546 1000183 1532556 1697737 1231042 1203289 0 0 1586061 1741864 2046496 1101064 0 0 2484287 0 1176707 0 0 1295600 1001256 0 0 0 1370912 0 0 242375 0 429103 454537 249814 0 0 404978 0 1044966 328116 274668 249045 448426 0 603090 446657 0 0 446537 0 859150 460409 0 0 887324 0 0 0 0 319155 1260267 0 0 0 657735 0 0 981745 0 1787114 1713228 1272261 0 0 516904 0 1101450 2080565 823041 1242986 1574720 745719 2354711 844788 0 0 1199378 2274016 967411 0 0 0 1417854 0 696211 0 0 783388 997057 0 0 0 1002940 -AAQAAAEAAAPEAE MGYG000001292_02324 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CYTW@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 K 1.0 Participates in both transcription termination and antitermination 1.0 nusA 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 1.0 - 1.0 ko:K02600 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009,ko03021 1.0 - 1.0 - 1.0 - 1.0 DUF448,KH_5,NusA_N,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604317 0 0 0 0 95926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQAAAGAAAGEK MGYG000002517_00513 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1645@1|root,COG1645@2|Bacteria,1TRYG@1239|Firmicutes,25F3V@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 bacterial-type flagellum-dependent swarming motility 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 600367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522837 659709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254863 265233 0 0 0 0 0 0 0 0 0 0 0 -AAQAAAGGPGLQVK MGYG000001302.1_01546 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG4770@1|root,COG4770@2|Bacteria,4NSWV@976|Bacteroidetes,2FRYI@200643|Bacteroidia,22UGJ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Biotin-requiring enzyme 1.0 mmdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401011 0 0 0 0 481225 0 0 0 0 377439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 913396 0 0 0 0 651176 0 0 0 0 677082 0 0 0 0 0 0 0 0 0 0 -AAQAAIAEK MGYG000000133_02955;MGYG000002298_01806;MGYG000000184_00575;MGYG000001687_00537;MGYG000004733_01907;MGYG000000171_00241;MGYG000000153_02081;MGYG000004785_01840;MGYG000000262_01988;MGYG000001637_01169;MGYG000003366_01811;MGYG000003694_01656 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.5833333333333334 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 431788 1263631 0 1939892 999547 0 0 0 0 1384803 0 0 170776 0 768335 302041 0 0 939973 0 1225112 0 464828 0 0 0 0 1023353 0 393201 891447 0 0 0 0 0 607088 0 221427 353281 0 414629 0 0 0 0 0 0 0 0 0 0 259650 165167 0 0 303285 0 387938 0 198703 0 0 0 0 375395 0 131086 149892 116414 0 0 0 0 174988 0 1061789 277486 0 241809 273706 0 0 0 0 258443 0 0 554931 0 325262 838084 0 0 661671 0 609313 0 198924 0 0 0 0 408538 0 213721 732883 778405 0 0 0 0 326205 0 6450057 2622319 0 3712527 1939140 0 0 0 0 2222398 0 0 1487938 0 3629355 2165121 0 0 2282936 0 2917292 0 6245899 0 0 0 0 6642659 0 13026683 2461823 2879180 0 0 0 0 7038591 0 350159 0 0 105206 82332 0 0 0 0 519258 0 0 0 0 147886 0 0 0 0 0 0 0 0 0 0 0 0 327195 0 287844 467701 0 0 0 0 0 149618 -AAQAAIANK MGYG000000231_00504;MGYG000001319_00729;MGYG000000280_02154;MGYG000000154_00436;MGYG000001374_00487;MGYG000002517_01243;MGYG000000245_03386;MGYG000000258_01879;MGYG000001698_00702;MGYG000004891_00190;MGYG000000076_02377 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 0.7272727272727273 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 489516 0 385267 731100 332873 291162 517251 614249 953885 720556 0 243094 0 565209 1312937 290870 0 3334053 923530 225792 728924 675049 2360573 0 1217231 632874 760421 3211089 309860 457636 0 469920 215027 929468 519806 0 657889 237548 0 0 0 100301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 544219 300595 294991 615967 0 240104 306567 952198 742089 712598 333248 412212 0 726249 1503551 416985 598170 0 1026388 1415569 1146003 0 72599 142459 909279 753374 953613 0 638572 421876 243754 0 224220 685030 994922 0 1171707 353852 6627809 3074590 1535342 9781989 3691510 2782062 4770740 5384114 9460165 3253508 2584203 3033519 0 8536661 2688221 4823675 7335930 2397084 6464423 10750128 1120760 1864436 206711 2205948 3530006 4781773 8244693 4998427 2981489 5801966 2809520 1838655 1098241 2203689 4629574 0 6821605 2925054 0 150498 0 0 1271147 719734 259769 0 2301525 600739 386186 0 0 726274 0 0 140522 271114 0 1760066 258443 1242785 341720 495915 0 0 0 0 1772952 0 0 128285 514767 0 1737496 0 272524 0 -AAQAAIKNPR MGYG000001647_00185;MGYG000004866_01031;MGYG000000022_02788;MGYG000001597_00394;MGYG000000312_02404;MGYG000000278_00304;MGYG000001157_01952;MGYG000003899_02226;MGYG000003921_00033;MGYG000003166_00833;MGYG000003819_01577;MGYG000002707_01357;MGYG000002545_01217;MGYG000000636_01370;MGYG000002274_02693;MGYG000002105_00879;MGYG000002224_02000;MGYG000001300_02837;MGYG000002953_01784;MGYG000001255_00900;MGYG000002040_00906;MGYG000004732_02304;MGYG000000087_02439 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.7391304347826086 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.9565217391304348 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 636700 441479 1043114 662313 766123 583986 537152 0 783994 799969 916963 674556 892456 921036 1140627 686911 0 1568674 1589254 846771 656872 830806 1259044 715816 987552 1030511 668069 1685119 599619 597497 716556 583072 993421 1081610 822547 0 706115 752209 230738 90968 194216 85876 185442 224407 266374 0 207315 149487 208306 207969 187239 273547 153880 174793 0 119593 334317 337987 73616 196172 206198 76587 250032 194350 185886 163749 174635 167659 80162 273577 156231 190107 138293 0 187521 145101 142202 222524 169255 307313 123779 242667 240761 0 177586 221818 212066 193201 194416 231003 204339 156270 0 284053 213208 155934 259202 146800 259574 206583 155985 261292 142290 394492 212354 208535 180594 81957 112796 204352 239414 0 248419 148863 535856 863542 1061895 788806 1016263 1057078 891941 0 843269 728392 715646 972787 780376 783269 637588 1003685 0 1217040 1097107 791269 314025 1235103 202884 2250046 398834 379076 659738 1454029 668621 871686 2151912 774391 1132291 582182 469673 0 572221 2153117 0 111288 43725 69043 103790 0 0 0 0 144569 0 0 193090 0 60302 94895 0 191923 100945 57655 64847 0 160992 180400 192124 183290 108803 89313 126712 167275 129545 127261 178966 0 145192 0 0 133277 -AAQAAINQK MGYG000000164_00358;MGYG000002279_01986;MGYG000004296_00104 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQAAISNK MGYG000000271_00388 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 580531 0 0 0 0 0 408270 0 672442 0 0 0 0 0 0 0 0 859431 798040 0 602074 0 582648 0 0 517133 0 845454 0 0 0 0 0 940131 0 446000 427564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294190 0 220576 0 0 0 0 144991 0 0 0 0 0 0 0 0 0 159168 71104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 149934 0 0 0 0 461017 0 0 0 0 0 0 0 0 0 0 381361 0 0 0 0 0 849983 0 526358 0 0 0 0 0 0 0 0 1224542 0 0 397075 0 329555 0 0 283437 0 952621 0 0 0 0 0 359056 0 192234 449268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQAALDEGLKELGK MGYG000000045_02091 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG4166@1|root,COG4166@2|Bacteria,2NPWR@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407036 0 0 0 0 370006 0 0 0 0 403272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2360134 0 0 0 0 1290348 0 0 0 0 1977437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304928 0 0 0 0 556341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70315 0 0 0 0 0 0 0 0 0 0 -AAQAALDEGLKELGKSEITIR MGYG000000045_02091 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG4166@1|root,COG4166@2|Bacteria,2NPWR@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing;ABC transporters;beta-Lactam resistance 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQAAVAPNTTEGGDK MGYG000002492_01486 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfE 1.0 - 1.0 - 1.0 ko:K03613 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS05585 1.0 FMN_bind,Rnf-Nqr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 860976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQAAVEDMK MGYG000002478_03849 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 852859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 315453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQAGDWATVK MGYG000004681_01408 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__|m__MGYG000004681 1.0 COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4CUG0@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 EM 1.0 Belongs to the DapA family 1.0 - 1.0 - 1.0 4.3.3.7 1.0 ko:K01714 1.0 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 1.0 M00016,M00525,M00526,M00527 1.0 R10147 1.0 RC03062,RC03063 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHDPS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-tetrahydrodipicolinate synthase. dihydrodipicolinate synthetase. The reaction can be divided into three consecutive steps: Schiff base formation with pyruvate, the addition of L-aspartate-semialdehyde, and finally transimination leading to cyclization with simultaneous dissociation of the product.-!-The product of the enzyme was initially thought to be (S)-2,3- dihydrodipicolinate, and the enzyme was classified accordingly as EC 4.2.1.52.-!-Later studies of the enzyme from the bacterium Escherichia coli have suggested that the actual product of the enzyme is (2S,4S)-4-hydroxy- 2,3,4,5-tetrahydrodipicolinate, and thus the enzyme has been reclassified as 4-hydroxy-tetrahydrodipicolinate synthase.-!-However, the identity of the product is still controversial, as more recently it has been suggested that it may be (S)-2,3- dihydrodipicolinate after all.-!-Formerly EC 4.2.1.52. L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5- tetrahydrodipicolinate + H(+) + H2O. 1.0 1.0 1.0 1.0 Monobactam biosynthesis;Metabolic pathways;Lysine biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1199672 0 0 0 0 1041285 0 0 0 0 1290547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1567264 0 0 0 0 746430 0 0 0 0 1348477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179032 0 0 0 0 445488 0 0 0 0 785999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 885696 0 0 0 0 1090679 0 0 0 0 1949158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210843 0 0 0 0 449461 0 0 0 0 279553 0 0 0 0 0 0 0 0 0 0 -AAQAIDAFDYR MGYG000000243_03324 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 5579398 5935580 17984410 6485355 6516747 4871087 7449644 6905584 6650214 4038527 3456570 3983652 5961607 5217164 5463361 6476279 6203688 2735028 4803027 4618842 5302920 4058916 4236158 6505759 5311724 4887281 5752213 3661205 6444841 4771737 11498542 6627666 19688785 6292788 5466058 6336246 5819165 16338919 2501279 0 442117 449118 2046586 0 0 0 2348549 6864907 358288 0 0 469160 493090 0 0 0 2274657 1648556 0 0 0 0 424529 0 0 0 1818002 2728087 737756 0 771251 746479 754039 529720 1907703 576780 254245 559081 455120 0 242753 0 706431 392173 869062 612469 640766 334403 281092 337321 892163 249586 956733 0 485558 501840 317675 776959 781542 400703 236081 455696 245872 445131 1079703 728571 788540 299569 504076 804898 519910 363098 0 860590 432317 336743 477477 561443 702618 333895 568622 650055 259180 538841 157882 142996 1092943 591416 415614 202594 177925 902039 922892 586749 0 324524 1245690 861623 660669 468856 307592 1458561 171570 522359 1322185 640060 710005 757185 663145 328353 471056 464476 0 373041 1048587 612893 332501 697784 377137 937593 310923 170952 254550 626467 0 0 977599 369572 869334 0 631136 384113 579134 0 0 243701 759202 0 475201 953695 1138918 0 755950 337769 820334 0 0 0 752344 565423 -AAQAQLPC(Carbamidomethyl)PEVTESAAPAK MGYG000002556_00167 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-279|s__CAG-279 sp000437795|m__MGYG000002556 1.0 COG2885@1|root,COG2885@2|Bacteria,4NKQC@976|Bacteroidetes,2FRBK@200643|Bacteroidia,22X13@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 - 1.0 GO:0001871,GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0006810,GO:0008150,GO:0015267,GO:0015288,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030246,GO:0030247,GO:0051179,GO:0051234,GO:0055085 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1869776 0 0 0 0 1515336 0 0 0 0 770351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQAVATM(Oxidation)R MGYG000002834_01329;MGYG000002549_01140;MGYG000002960_01369;MGYG000004876_01717;MGYG000004561_01315;MGYG000001783_00644;MGYG000000236_00811;MGYG000002455_04080;MGYG000000196_03727;MGYG000001337_00793;MGYG000003697_00353 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 0.6363636363636364 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQAVATMR MGYG000002834_01329;MGYG000002549_01140;MGYG000002960_01369;MGYG000004876_01717;MGYG000004561_01315;MGYG000001783_00644;MGYG000000236_00811;MGYG000002455_04080;MGYG000000196_03727;MGYG000001337_00793;MGYG000003697_00353 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 0.6363636363636364 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 2601739 0 0 2828075 1815854 2608457 2690686 2145872 2710639 2438144 1332173 2197791 1871842 3170151 3224222 1498983 1773883 412957 2737599 3669321 2961409 2366548 768107 2053648 3077157 2575818 2238524 470274 2729060 2326988 1745006 2112682 1758869 2491608 0 2327487 2452914 1867831 2201785 0 1499862 2097610 0 0 0 0 1540472 2152970 1348145 1619852 1178961 1786743 2202225 1297299 1577273 0 1839511 1771980 2187372 0 1038328 1041814 1867881 2362873 1732045 741032 0 1687104 797462 1085145 1645091 1859507 0 0 1932041 1693415 0 0 2565329 1730030 1747856 1668600 2135352 0 2673930 0 1398941 1595606 1785050 2013188 2399274 1729096 0 1012187 1795129 2772187 2745647 0 1049970 1677419 0 2282112 2779353 685568 2656652 2023539 1398990 0 1089360 2449228 0 2498092 2374823 1744128 2591922 0 3065762 2002679 4356504 2937156 2303340 2568703 2600143 2487450 2115229 2492800 3063165 1633107 2694789 3698288 2762964 4797657 1800024 2376724 1668326 4137331 2411138 2854416 2109742 2520904 2506892 3719410 4402046 1851353 3205141 3948511 2196369 2792648 0 2362966 2283898 2723227 5737344 0 3711352 5738984 3764486 3613299 4531792 4016166 4071289 4457242 2888450 3939939 5943911 3562191 4588503 4395966 3955899 1607119 4556646 3963439 4563055 4149610 1259764 4130611 4459077 5762021 4626216 829618 1906211 4857226 3165149 4573938 4023352 5338995 0 6381223 4400150 0 -AAQAVIGETLVR MGYG000000249_00979;MGYG000002772_02240 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter 1.0 COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TPR4@1239|Firmicutes,248TM@186801|Clostridia,36EWP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 selenate reductase YgfK 1.0 - 1.0 - 1.0 1.97.1.9 1.0 ko:K12527 1.0 ko00450,map00450 1.0 - 1.0 R07229 1.0 RC02420 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4_20,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 selenate reductase. - The periplasmic enzyme from Thauera selenatis is a complex comprising three heterologous subunits (alpha, beta and gamma).-!-Nitrate, nitrite, chlorate and sulfate are not substrates.-!-A number of compounds, including acetate, lactate, pyruvate, and certain sugars, amino acids, fatty acids, di- and tricarboxylic acids, and benzoate can serve as electron donors. A + H2O + selenite = AH2 + selenate. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 none 1.0 585805 0 0 423901 0 790879 187838 0 0 0 0 0 0 0 0 0 0 0 0 481321 0 754190 0 1229372 355819 471707 0 0 423081 0 0 0 0 867501 957848 518004 567226 0 2916750 0 0 2391800 0 1441614 2770677 0 0 0 0 0 0 0 0 0 0 0 0 2754127 0 0 0 3570364 2416273 2170111 0 0 2545301 0 0 0 0 3420311 3134984 3216574 2508607 0 400583 0 0 585428 0 240139 295629 0 0 0 0 0 0 0 0 0 0 0 0 244015 0 124143 0 416739 348844 182838 0 0 55809 0 0 0 0 490692 254471 297047 236422 0 863391 0 0 649787 0 1163702 1007722 0 0 0 0 0 0 0 0 0 0 0 0 707824 0 1332962 0 1020590 262236 972704 0 0 544287 0 0 0 0 161221 672077 639678 781161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQDALENGTGK MGYG000001313_03153 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,4AKGG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428011 0 0 0 0 0 0 0 0 0 0 1492350 0 0 0 0 1042868 0 0 0 0 961783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQDDADVQSAVR MGYG000002279_01925 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena_B|m__MGYG000002279 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,27V02@189330|Dorea 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate 1.0 glmM 1.0 - 1.0 5.4.2.10 1.0 ko:K03431 1.0 ko00520,ko01100,ko01130,map00520,map01100,map01130 1.0 - 1.0 R02060 1.0 RC00408 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglucosamine mutase. - The enzyme is involved in the pathway for bacterial cell-wall peptidoglycan and lipopolysaccharide biosyntheses, being an essential step in the pathway for UDP-N-acetylglucosamine biosynthesis.-!-The enzyme from Escherichia coli is activated by phosphorylation and can be autophosphorylated in vitro by alpha-D-glucosamine 1,6- bisphosphate, which is an intermediate in the reaction, alpha-D- glucose 1,6-bisphosphate or ATP.-!-It can also catalyze the interconversion of alpha-D-glucose 1-phosphate and alpha-D-glucose 6-phosphate, although at a much lower rate. alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 823552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 808762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQDDILK MGYG000002494_02921 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,3XNGC@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) 1.0 ileS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.5 1.0 ko:K01870 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03656 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iG2583_1286.G2583_0027,iPC815.YPO0475 1.0 Acetyltransf_3,Anticodon_1,FAD_syn,Flavokinase,tRNA-synt_1,zf-FPG_IleRS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 isoleucine--tRNA ligase. isoleucyl-tRNA synthetase. - ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2288668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2715538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQDGHLADFAFQC(Carbamidomethyl)TGNPHAHANIYK MGYG000000171_01275 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3WS7A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Glucose dehydrogenase C-terminus 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 262804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 779903 0 0 806061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQDLNSEQLNK MGYG000001313_01935 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG1629@1|root,COG3188@1|root,COG1629@2|Bacteria,COG3188@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4ANM7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 NPU 1.0 Psort location OuterMembrane, score 9.49 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321033 0 0 0 0 467589 0 0 0 0 509489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1000109 0 0 0 0 757252 0 0 0 0 747764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQDTVDR MGYG000000271_03640 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 487083 0 0 0 0 0 958974 0 0 0 828116 996483 0 0 0 0 0 0 0 0 831572 0 0 0 920308 570648 777553 0 0 1015838 0 0 0 0 0 0 0 0 213086 0 0 0 0 0 233144 0 0 0 396350 0 0 0 0 0 0 0 0 0 210613 0 0 0 0 162816 100186 0 0 176781 0 0 0 0 0 0 174774 0 152057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQDTVDRITK MGYG000000271_03640 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQDYMLQEVQR MGYG000001315_01195 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3XYSW@572511|Blautia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 657461 0 0 0 0 0 0 0 593827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467613 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343529 0 0 0 0 367828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167098 0 0 492198 0 0 0 0 0 0 0 195514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 501571 0 0 0 0 772935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1170794 0 0 0 0 0 -AAQEAAANQDTR MGYG000003697_01634 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,2FMVF@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane 1.0 secA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 1.0 - 1.0 ko:K03070 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 1.0 - 1.0 - 1.0 Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Protein export;Quorum sensing;Bacterial secretion system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1704439 0 0 1314102 0 641514 0 0 1324832 0 756164 0 508139 1221362 0 1766060 0 0 0 1764799 715524 1578068 0 0 0 2027660 567724 0 750253 777986 1176116 571170 603440 0 0 1466813 0 0 167576 0 0 0 0 0 0 0 0 0 0 0 205702 0 0 0 0 0 0 0 0 136252 0 0 0 0 299057 0 534963 0 147553 266245 0 0 0 158537 -AAQEAGDTDKVKK MGYG000000022_02302 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,3WGY6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Molecular chaperone. Has ATPase activity 1.0 htpG 1.0 - 1.0 - 1.0 ko:K04079 1.0 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HATPase_c_3,HSP90 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Estrogen signaling pathway;Antigen processing and presentation;Necroptosis;Prostate cancer;NOD-like receptor signaling pathway;Plant-pathogen interaction;Protein processing in endoplasmic reticulum;Th17 cell differentiation;Progesterone-mediated oocyte maturation;Fluid shear stress and atherosclerosis;Pathways in cancer;IL-17 signaling pathway;PI3K-Akt signaling pathway 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185749 0 0 0 0 326574 0 0 0 0 450231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267320 0 0 0 0 67350 0 0 0 0 276849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223140 0 0 0 0 386716 0 0 0 0 91588 0 0 0 0 0 0 0 0 0 0 -AAQEALEN(Deamidated)GTGK MGYG000002455_01614;MGYG000001780_00268;MGYG000004876_01420;MGYG000001346_00849;MGYG000003681_00158 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,4AKGG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 391486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 722902 0 1110648 1194936 0 1241872 0 0 0 1359082 1136369 1603636 0 0 0 0 0 384681 0 0 0 1213750 555846 897315 0 1150373 0 584781 0 971855 0 0 1135873 1183863 0 0 1280036 1040492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220706 0 0 337142 0 197409 0 0 0 264848 357621 489825 0 0 0 0 0 0 0 0 0 251456 0 0 0 181054 0 387873 0 259130 0 0 0 423915 0 0 395218 228574 227040 0 0 0 0 166529 0 0 0 0 894434 0 0 0 0 0 0 540888 0 0 0 98379 414581 0 0 244054 0 381697 0 279488 0 0 0 267078 0 0 190588 129845 -AAQEALENGTGK MGYG000002455_01614;MGYG000001780_00268;MGYG000004876_01420;MGYG000001346_00849;MGYG000003681_00158 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,4AKGG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 560555 0 0 0 0 0 0 317685 0 0 0 0 235753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587829 0 733087 331776 0 0 0 0 328149 0 355161 0 0 0 0 636824 0 401248 0 0 491685 0 442781 0 0 0 320537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 779177 0 0 0 0 0 0 992138 0 0 0 0 644531 0 0 0 0 617282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174255 0 0 0 0 0 0 285833 0 0 0 0 0 0 163985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550259 0 0 1174647 0 0 0 0 488417 0 1748657 0 0 0 0 1103937 0 438013 0 0 785670 0 776289 0 0 0 623115 0 0 0 0 -AAQEEEFSLELR MGYG000000093_03534;MGYG000002506_04281;MGYG000002477_04491;MGYG000002494_03044;MGYG000002323_00741;MGYG000003372_02025;MGYG000001465_03792;MGYG000002504_00584;MGYG000002515_00161;MGYG000003390_04763;MGYG000002534_00996;MGYG000002535_03440 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,3ZK8D@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon 1.0 gluQ 1.0 GO:0000166,GO:0002097,GO:0003674,GO:0005488,GO:0005524,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 1.0 - 1.0 ko:K01894 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 tRNA-synt_1c 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 596089 559656 296051 0 484713 847588 561554 828340 0 0 0 784783 0 0 377821 0 0 0 659705 573366 520770 794064 0 1080944 950791 634940 669899 0 765152 1013052 0 0 688436 642223 700891 0 555848 463509 977674 1030501 1306306 0 1160230 1957023 1193660 1150772 0 0 0 1303822 0 0 1116356 0 0 0 1476675 1196003 1451897 2697319 0 1728229 1304377 1073321 1072521 0 1814638 1392504 0 0 1161299 1129843 1150503 0 841116 1266437 691492 382040 404625 0 678711 1169441 268010 443711 0 0 0 462597 0 0 668560 0 0 0 0 494999 377473 983164 0 923818 483919 445964 725744 0 662177 472247 0 0 507214 637012 369510 0 167867 436866 826415 679484 748913 0 1003737 1056533 1168904 1116486 0 0 0 849682 0 0 947296 0 0 0 961631 774870 991616 629620 0 920864 1150210 991884 822903 0 836975 1081024 0 0 697830 1432431 1280918 0 665493 528633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210862 0 0 0 0 0 0 0 0 -AAQEGIVFSFK MGYG000002455_04126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,2FPIS@200643|Bacteroidia,4AMYR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Carbohydrate kinase, FGGY family protein 1.0 xylB_2 1.0 - 1.0 2.7.1.17 1.0 ko:K00854 1.0 ko00040,ko01100,map00040,map01100 1.0 M00014 1.0 R01639 1.0 RC00002,RC00538 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 xylulokinase. Xylulose kinase. - ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+). 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 414039 0 0 0 0 0 0 0 0 0 465651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 800532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1320747 0 0 0 0 1069679 0 0 0 0 968055 0 0 0 0 0 0 0 0 0 0 -AAQEKLTQSAQK MGYG000000271_02474;MGYG000004271_00836 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - worm;Tuberculosis;RNA degradation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQELFDVSQVR MGYG000002494_01268;MGYG000002477_03573;MGYG000003372_00988;MGYG000002534_01961 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria 0.75 1236|Gammaproteobacteria 1.0 S 1.0 Belongs to the WrbA family 0.75 wrbA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016043,GO:0016491,GO:0016651,GO:0016655,GO:0022607,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 1.6.5.2 1.0 ko:K03809 1.0 ko00130,ko01110,map00130,map01110 1.0 - 1.0 R02964,R03643,R03816 1.0 RC00819 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FMN_red 1.0 - 1.0 AA6 1.0 AA6 1.0 - 1.0 NAD(P)H dehydrogenase (quinone). vitamin-K reductase. The enzyme catalyzes a two-electron reduction and has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone.-!-The animal, but not the plant, form of the enzyme is inhibited by dicoumarol.-!-Formerly EC 1.6.99.2. (1) a quinone + H(+) + NADH = a quinol + NAD(+). (2) a quinone + H(+) + NADPH = a quinol + NADP(+). 1.0 1.0 1.0 1.0 Ubiquinone and other terpenoid-quinone biosynthesis;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 139169 367640 0 349690 494359 0 0 0 0 0 277364 291174 0 560391 0 0 507894 0 431494 416882 0 0 0 917497 0 0 0 367235 0 0 0 0 632369 0 0 824167 0 0 2058336 499810 0 534016 676362 0 0 0 0 0 574816 908572 0 864352 0 0 2668766 0 1648765 614870 0 0 0 976429 0 0 0 977369 0 0 0 0 559687 0 0 0 0 0 527066 0 0 0 233759 0 0 0 0 0 365162 0 0 348020 0 0 427136 0 229816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384232 0 0 0 0 0 0 0 0 0 0 0 0 478785 0 0 0 0 0 483562 0 0 0 0 0 0 439398 0 0 0 313464 0 0 0 0 865539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQEMLEK MGYG000001378_04145;MGYG000000196_02254 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,4AKGG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 1051207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1305934 0 1378544 0 0 0 0 0 0 0 1598398 0 0 0 1131778 0 0 0 0 0 0 0 1375572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546110 0 1287518 0 0 0 0 0 0 0 1121352 0 0 0 1279303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 978401 0 892209 0 0 0 0 0 0 0 801201 0 0 0 0 0 0 0 0 0 0 0 862237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1039820 0 1166708 0 0 0 0 0 0 0 1767832 0 0 0 1870494 0 0 0 0 0 0 0 1523266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1441537 0 1265440 0 0 0 0 0 0 0 445364 0 0 0 697578 0 0 -AAQEQLATAK MGYG000002293_00897 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,2FNVT@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 N 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02557 1.0 ko02030,ko02040,map02030,map02040 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02000,ko02035 1.0 1.A.30.1 1.0 - 1.0 - 1.0 OmpA,ZapB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Flagellar assembly 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1971115 0 0 0 3949055 0 0 0 0 0 0 0 0 0 1459939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQEQLSSTKK MGYG000003697_02770 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,2FNVT@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 N 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02557 1.0 ko02030,ko02040,map02030,map02040 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02000,ko02035 1.0 1.A.30.1 1.0 - 1.0 - 1.0 OmpA,ZapB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Flagellar assembly 1.0 none 1.0 0 0 412415 0 0 402215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663977 0 828986 0 0 0 0 0 0 0 0 0 0 0 0 0 560669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 637675 0 0 536606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775081 0 786921 0 0 0 0 0 0 705356 0 467525 0 0 0 0 858169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQFVASHD(Asp->Pro)GEVC(Carbamidomethyl)PAK MGYG000004763_00297 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG0450@1|root,COG0450@2|Bacteria,4NEDT@976|Bacteroidetes,2FMG5@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 O 1.0 Peroxiredoxin 1.0 ahpC 1.0 - 1.0 1.11.1.15 1.0 ko:K03386 1.0 ko04214,map04214 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 1-cysPrx_C,AhpC-TSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 and 1.11.1.29. - - - 1.0 1.0 1.0 1.0 Apoptosis - fly 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1795468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQGGINAAK MGYG000004797_00778;MGYG000003697_02283;MGYG000004006_00370;MGYG000001461_00141;MGYG000001302.1_00465;MGYG000002478_01127;MGYG000001337_00566;MGYG000000074_01707;MGYG000001346_01988;MGYG000002203_00448;MGYG000000236_03409;MGYG000003681_02554;MGYG000001489_01892;MGYG000000054_01799;MGYG000003363_00071;MGYG000004757_00444;MGYG000001415_01060;MGYG000001480_02130;MGYG000000098_00498;MGYG000002293_02708;MGYG000003701_02816;MGYG000002438_01315;MGYG000001666_01263;MGYG000000003_02554;MGYG000004876_01120;MGYG000001345_04416;MGYG000002905_00555;MGYG000000354_00310;MGYG000000303_00634;MGYG000001789_02670;MGYG000001313_00346;MGYG000001546_01596;MGYG000004848_01076;MGYG000000414_00982;MGYG000000196_02827 domain d__Bacteria 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 0.4857142857142857 976|Bacteroidetes 0.9428571428571428 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 0.4857142857142857 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 0.9428571428571428 ko:K00239 0.9428571428571428 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 0.9428571428571428 M00009,M00011,M00149,M00173,M00374,M00376 0.9428571428571428 R02164 0.9428571428571428 RC00045 0.9428571428571428 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 0.9428571428571428 0.9428571428571428 0.9428571428571428 0.9428571428571428 Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 0.9428571428571428 none 1.0 0 0 1748004 0 1928035 1308846 0 1430659 0 0 0 1397952 0 0 0 0 1664041 0 1626218 0 1392113 2316856 0 1836282 1438300 0 0 0 0 1668361 0 1840138 1331963 0 0 1296151 0 2457002 0 0 1212969 0 1557870 1090704 0 1771448 0 0 0 1591408 2038541 0 0 0 1512953 0 1449396 0 1337045 1146119 0 780685 1033897 0 0 0 0 1546035 0 1425871 885530 0 0 1292069 0 771867 0 0 1595342 0 1616446 1927906 0 1667189 0 0 0 1630010 1722787 0 0 0 1191701 0 1195335 0 2014978 1183168 0 1430873 1029649 0 0 0 0 921806 0 1372147 1597614 0 0 1834714 0 1658246 0 0 2737867 0 3004680 2342726 0 1863362 0 0 0 2579417 1496921 0 0 0 2041682 0 1659774 0 745502 3870161 0 2920957 1498432 0 0 0 0 1821020 0 2226929 1593883 0 0 746425 0 3756105 0 0 610223 0 793219 517875 0 647304 0 0 0 559418 937995 0 0 0 403873 0 955565 0 1462383 1099836 0 1096802 779795 0 0 0 0 1200581 0 597012 709799 0 0 519292 0 496632 -AAQGGLSTILFEK MGYG000002438_01509 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,2FM8Y@200643|Bacteroidia,22WU2@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Dihydrolipoyl dehydrogenase 1.0 lpdA 1.0 - 1.0 1.8.1.4 1.0 ko:K00382 1.0 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00036,M00307,M00532 1.0 R00209,R01221,R01698,R03815,R07618,R08549 1.0 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 1.0 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2,Pyr_redox_dim 1.0 - 1.0 - 1.0 - 1.0 - 1.0 dihydrolipoyl dehydrogenase. L-protein. A component of the multienzyme 2-oxo-acid dehydrogenase complexes.-!-In the pyruvate dehydrogenase complex, it binds to the core of EC 2.3.1.12 and catalyzes oxidation of its dihydrolipoyl groups.-!-It plays a similar role in the oxoglutarate and 3-methyl-2- oxobutanoate dehydrogenase complexes.-!-Another substrate is the dihydrolipoyl group in the H-protein of the glycine-cleavage system, in which it acts, together with EC 1.4.4.2 and EC 2.1.2.10 to break down glycine.-!-It can also use free dihydrolipoate, dihydrolipoamide or dihydrolipoyllysine as substrate.-!-Was first shown to catalyze the oxidation of NADH by methylene blue; this activity was called diaphorase.-!-The glycine cleavage system is composed of four components that only loosely associate: the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H protein.-!-Formerly EC 1.6.4.3. N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = H(+) + N(6)-[(R)- lipoyl]-L-lysyl-[protein] + NADH. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon metabolism;Metabolic pathways;Biosynthesis of secondary metabolites;Glycolysis / Gluconeogenesis;Glycine, serine and threonine metabolism;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 233426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 346375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 999529 0 0 0 0 0 0 0 0 0 0 679435 0 0 0 0 0 0 -AAQGGMQASLANVIK MGYG000003022_01475;MGYG000003352_00541 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,1KJ0V@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 C 1.0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239,ko:K00244 1.0 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 1.0 M00009,M00011,M00149,M00150,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Legionellosis;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 529166 0 259079 636716 0 336027 432732 0 725303 452753 0 670328 0 540355 141830 140815 557970 0 0 449689 0 370487 0 355371 0 0 449267 0 0 584725 0 388329 0 650558 0 0 434871 0 823883 582698 1041156 1030649 929815 924587 831348 1520562 832036 986647 1218269 980864 0 862100 903837 775088 839757 0 884527 695254 0 849459 0 914721 0 890118 941336 0 0 1038920 0 840347 839004 800742 1613882 841413 767939 665823 0 0 479783 231194 0 426119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 274556 0 0 0 0 535190 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237776 0 0 0 0 280018 319232 0 430257 0 0 0 0 374354 334368 0 314632 0 420649 313643 0 0 0 296616 0 336770 319704 0 0 304276 0 0 0 395189 0 302988 287221 0 -AAQGGMQASLGNVIK MGYG000004704_00059;MGYG000001410_00319 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella 1.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,4PQQW@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 C 1.0 Fumarate reductase flavoprotein C-term 1.0 frdA 1.0 - 1.0 1.3.5.4 1.0 ko:K00244 1.0 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 1.0 M00009,M00011,M00150,M00173 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Oxidative phosphorylation;Two-component system;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 374209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 430512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517106 612207 0 447416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496786 0 0 0 0 0 0 1947609 0 0 0 0 1203878 0 0 0 0 1166996 0 0 0 0 919817 0 0 852931 0 964150 0 1084237 883322 0 0 978130 2279160 0 1396935 0 -AAQGILTVR MGYG000000463_01481;MGYG000002114_00088;MGYG000002229_00282;MGYG000002006_01658;MGYG000004482_00393;MGYG000004594_00959;MGYG000004667_00970;MGYG000002727_00240;MGYG000001319_00729;MGYG000004680_00577;MGYG000000145_01088;MGYG000004760_00878;MGYG000002670_01671;MGYG000001688_03814;MGYG000001698_00702;MGYG000002926_01683;MGYG000001757_01805;MGYG000002143_00035;MGYG000002057_00345;MGYG000000728_00587;MGYG000002103_01314;MGYG000000084_02423;MGYG000000205_02701;MGYG000000152_05136;MGYG000004663_01541;MGYG000004866_01724;MGYG000002059_01602;MGYG000004380_01725;MGYG000002025_01833;MGYG000004475_00310;MGYG000003422_01232;MGYG000000242_00224;MGYG000002139_00077;MGYG000002794_01254;MGYG000004718_01489;MGYG000004517_00262;MGYG000001733_00637;MGYG000000175_01356;MGYG000002552_02286;MGYG000000404_01435;MGYG000000387_01345;MGYG000004784_01123;MGYG000002492_01692;MGYG000004845_02015;MGYG000001439_01567;MGYG000000371_01679;MGYG000000489_00801;MGYG000000281_03419;MGYG000000142_02834;MGYG000002702_00763;MGYG000002099_01951;MGYG000004487_00114;MGYG000000233_02503;MGYG000000031_02405;MGYG000001619_00896;MGYG000000179_00100;MGYG000000690_00823;MGYG000003074_00103;MGYG000000255_02207;MGYG000001564_02842;MGYG000000198_00250;MGYG000002945_01502;MGYG000001496_03326;MGYG000003921_01571;MGYG000001748_00979;MGYG000001675_00187;MGYG000003628_00298;MGYG000001646_00500;MGYG000003656_02122;MGYG000002925_01270;MGYG000002126_00460;MGYG000003694_01656;MGYG000001637_01169;MGYG000000087_02439 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.17567567567567569 186801|Clostridia 1.0 G 0.9459459459459459 Belongs to the PEP-utilizing enzyme family 0.6756756756756757 ppdK 0.9459459459459459 - 1.0 2.7.9.1 0.9459459459459459 ko:K01006 0.9459459459459459 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.9459459459459459 M00169,M00171,M00172,M00173 0.9459459459459459 R00206 0.9459459459459459 RC00002,RC00015 0.9459459459459459 ko00000,ko00001,ko00002,ko01000 0.9459459459459459 - 0.9459459459459459 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9459459459459459 - 1.0 - 1.0 - 1.0 GT1 0.9459459459459459 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.9459459459459459 0.9459459459459459 0.9459459459459459 0.9459459459459459 Pyruvate metabolism;Carbon metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Carbon fixation in photosynthetic organisms 0.9459459459459459 none 1.0 3194457 2831118 3464559 3115777 3404336 3101604 3042715 4660479 3395673 3894702 5219194 3122776 3216090 3559192 4209264 3476708 4074932 9737069 2372861 3474059 3648671 2808644 9405915 2875471 4012131 3089365 3390734 10799457 3443041 2743033 2966375 2941220 3096229 3649509 4277632 3548755 3522498 3171834 4849352 3986915 6180819 4017071 7298774 2797554 4300692 3750600 3996028 3900634 7128919 2048206 5799007 2830867 3190555 3913948 2319139 24217990 3131213 4092222 3189302 2526948 14835436 3830537 3279461 3508037 5018327 20138796 4293951 2607969 8951235 10864777 7184182 5374210 4969981 5733529 4543391 8731855 11868559 11202468 36027200 13016059 11474867 8326267 10439267 12964486 9833894 12465320 13896375 9744785 15144721 12003260 12831846 19123376 11011756 7061913 10789991 10700858 9685608 11676132 12455446 8916316 12520783 11457574 12801568 16690068 12573170 12492808 12551275 12065826 33674292 14754883 13735699 8828348 13018994 32946203 1428224 1342943 1596142 1267241 1413992 1264644 1385486 1037554 1341019 1546574 1566979 994107 1163788 1509715 1429381 1761511 1603809 1419336 875723 1776190 1275324 1950449 1516525 1787408 906546 924906 1738984 666393 2069121 473569 2573652 948984 1865527 842133 930020 1202944 1193690 2041317 2551411 1529528 4495656 2531390 2108584 5184368 3591264 3111450 2563877 2928281 2350566 2139749 1180574 3600781 2250076 1862440 2067734 3907961 2595004 1997662 2058144 4805364 6018939 3983363 2753311 1836154 2792981 6032711 4272997 1184546 3399268 2107595 8082641 3299839 2841989 2308297 1690592 4281867 -AAQGMWQDR MGYG000000802_01645;MGYG000003274_00635;MGYG000003266_00911 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4CVSZ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL17 family 1.0 rplQ 1.0 - 1.0 - 1.0 ko:K02879 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 2694326 0 0 372653 0 0 0 0 0 560957 0 1422720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358781 0 0 313986 0 0 0 0 0 622830 0 808956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215540 0 0 378817 0 0 0 0 0 0 0 406898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458759 0 0 999948 0 0 0 0 0 1661249 0 2578690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352197 0 0 420573 0 0 0 0 0 598433 0 126552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQGNNFGTVLIPEGLIEFIPAMK MGYG000004876_02004;MGYG000002455_02781 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7324062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 26192594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQGNNFGTVLIPEGLIEFIPAMKR MGYG000004876_02004;MGYG000004797_01062;MGYG000001780_01920 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1325382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1714109 0 0 0 0 0 0 0 0 0 0 0 2342888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21596852 0 0 0 0 0 0 0 3280869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5255623 0 0 0 0 0 0 0 -AAQGNNFGTVLIPEGLVEFIPAMKR MGYG000003681_01737;MGYG000000243_02424;MGYG000000196_00779 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Methane metabolism;Metabolic pathways;Glycolysis / Gluconeogenesis;Fructose and mannose metabolism;Galactose metabolism;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 1497726 0 1667695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14567704 0 0 0 0 0 0 0 0 0 3972171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10755160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQGQNVAR MGYG000004525_00228;MGYG000002670_01511;MGYG000000997_00552;MGYG000000489_01023;MGYG000002727_00924;MGYG000000280_01473;MGYG000002143_01933;MGYG000004487_00561;MGYG000003215_01534;MGYG000000389_02151;MGYG000004271_00231;MGYG000001616_02334;MGYG000000245_02019;MGYG000000271_02104;MGYG000001637_02269;MGYG000001711_01126;MGYG000001186_01723;MGYG000002517_00540;MGYG000003694_00877;MGYG000000153_01463;MGYG000004475_01257;MGYG000002492_00657 domain d__Bacteria 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.6818181818181818 186801|Clostridia 0.9545454545454546 I 1.0 Belongs to the thiolase family 0.6818181818181818 thlA 0.9545454545454546 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 3508440 2511029 784078 2492207 3163089 655332 752658 2500920 2638599 3400973 1110053 2872812 1760483 4091456 6872611 1203378 1148337 934166 3799235 366499 2843474 562691 646036 878224 3006449 3440318 2407475 784546 985773 3687771 1196172 424416 1194501 3726401 1814005 1471135 2216270 1590613 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3353658 232405 1670218 650375 513932 357476 1093770 777870 1274719 1837992 1430376 391782 1196289 1530858 1596596 1247216 1442636 0 730398 846836 1181906 265828 182385 1846100 2020035 3845146 1025478 272072 411382 542240 573422 159885 2919993 818570 1323281 1989606 1443993 3328890 1437777 1012529 870778 7851845 631566 2632048 15693514 5459159 15141397 3640235 4092338 1700090 5263440 7567521 6922211 1733667 2237395 913979 10176779 13305053 11505869 1155876 938396 1247053 8071725 5055946 2876480 997203 1962819 2197718 3146076 1995367 1296005 1062574 3992044 6646376 6068827 647429 171485 0 0 217447 0 60725 122699 0 84067 134808 0 27927 129550 0 0 0 0 0 186692 187214 41917 0 0 197241 196953 164057 208425 0 159602 362757 87917 0 0 0 260728 131454 454264 165519 -AAQGTVIEAR MGYG000002156_00834;MGYG000002720_01209 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,2N6M6@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 637048 0 454950 0 0 0 0 0 0 0 0 0 0 0 0 1241350 0 0 0 0 0 0 0 0 0 439142 0 0 0 0 0 0 632533 0 0 0 570822 1130642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 957141 564553 881659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 628205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 701879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 474894 0 0 0 0 0 -AAQGW(Trp->Ser)AEEDGTWVYYDR MGYG000000198_05887 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,21ZAM@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 408236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 780068 0 0 0 0 552829 0 0 533382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 694212 0 0 0 0 1119505 0 0 813826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802217 0 0 0 0 584027 0 0 2294558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQIIEPALTDPSTANDPETWK MGYG000003693_01133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0AS@200643|Bacteroidia,4AMX1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MbeB_N,TPR_1,TPR_11,TPR_16,TPR_17,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 729264 0 0 0 0 1092874 0 0 0 0 774340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQIISR MGYG000000142_02731;MGYG000001338_01296;MGYG000002528_00119;MGYG000001698_03439;MGYG000002275_01873;MGYG000000205_02543;MGYG000001627_00963;MGYG000000262_01832;MGYG000001770_01218;MGYG000002834_01893;MGYG000002108_00627;MGYG000002517_01686;MGYG000000212_00326;MGYG000002492_01963;MGYG000000029_00187;MGYG000000196_00899;MGYG000000280_02029;MGYG000000233_02118;MGYG000001599_00424;MGYG000000707_02290;MGYG000001707_00757;MGYG000001346_01121;MGYG000000215_01600;MGYG000003937_01695;MGYG000001871_01775;MGYG000003425_04615;MGYG000004733_02764;MGYG000002293_01605 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.21428571428571427 186801|Clostridia 0.5 S 0.9285714285714286 Psort location Cytoplasmic, score 8.96 0.42857142857142855 - 0.9285714285714286 - 1.0 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 1.0 - 1.0 - 1.0 GGGtGRT 0.9285714285714286 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.9285714285714286 0.9285714285714286 0.9285714285714286 0.9285714285714286 0.9285714285714286 none 1.0 0 0 186253 1854462 317275 0 2333953 0 91343 0 0 1750091 0 254570 0 285784 0 0 0 0 0 0 0 0 663738 0 0 0 0 0 2071688 0 1892111 0 0 155150 0 1881763 0 0 238626 455583 171871 0 866437 471972 351316 0 357056 167872 0 224708 0 1471865 0 0 293483 438875 0 0 0 0 1061190 0 0 0 1396986 0 756051 0 1439465 0 381372 654769 0 1136320 0 0 1491699 682836 869340 0 720980 619598 1359725 0 997871 532770 0 971370 706566 1010617 0 0 522858 811031 0 0 0 0 1211244 0 0 0 926207 0 842999 0 873751 0 551449 688363 0 1103481 0 0 1415659 2160560 1498290 0 2128979 1780318 1452188 0 1519302 1459361 0 1198782 1819674 1082708 0 0 1141297 1251440 0 0 0 0 984264 0 0 0 1553688 0 967455 0 1418726 0 2035971 1489702 0 2676158 0 0 1331179 2864948 2321839 0 1467440 0 1174736 0 2870354 507276 0 1315477 2007247 1890564 0 0 1529933 2224194 0 0 0 0 2230383 0 0 0 1203201 0 128813 0 2562220 0 0 2032899 0 2335234 -AAQITTNAAHDTHPVWSPDGK MGYG000000243_00233 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,2FPGA@200643|Bacteroidia,4ANRZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tricorn protease homolog 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 469907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235613 0 0 0 0 1191693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQIWYENDGDLSVLEGK MGYG000003683_01408;MGYG000002469_00124 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CZBR@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283784 0 0 0 0 0 0 968929 0 0 0 0 1489344 0 0 0 0 640637 757615 0 0 0 1089566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQIYINAR MGYG000003693_00757 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0235@1|root,COG0235@2|Bacteria,4NIQK@976|Bacteroidetes,2FN5U@200643|Bacteroidia,4AN95@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases 1.0 rhaD 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 1.0 4.1.2.19 1.0 ko:K01629 1.0 ko00040,ko00051,ko01120,map00040,map00051,map01120 1.0 - 1.0 R01785,R02263 1.0 RC00438,RC00599,RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 rhamnulose-1-phosphate aldolase. L-rhamnulose-phosphate aldolase. - L-rhamnulose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions;Microbial metabolism in diverse environments;Fructose and mannose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1384090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579566 0 0 0 0 0 0 0 0 0 1470936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353589 0 0 0 0 355344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQLGGK MGYG000002528_00904 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 FAD linked oxidases, C-terminal domain 1.0 glcD1 1.0 - 1.0 1.1.3.15 1.0 ko:K00104 1.0 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 1.0 - 1.0 R00475 1.0 RC00042 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD-oxidase_C,FAD_binding_4 1.0 - 1.0 AA7 1.0 - 1.0 - 1.0 (S)-2-hydroxy-acid oxidase. hydroxy-acid oxidase B. Exists as two major isoenzymes; the A form preferentially oxidizes short-chain aliphatic hydroxy acids; the B form preferentially oxidizes long-chain and aromatic hydroxy acids.-!-The rat isoenzyme B also acts as EC 1.4.3.2.-!-Formerly EC 1.1.3.1. a (2S)-2-hydroxycarboxylate + O2 = a 2-oxocarboxylate + H2O2. 1.0 1.0 1.0 1.0 Microbial metabolism in diverse environments;Metabolic pathways;Biosynthesis of secondary metabolites;Glyoxylate and dicarboxylate metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604516 0 0 0 0 506429 0 0 0 0 554837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511179 0 0 0 0 871747 0 0 0 0 613619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1613056 0 0 0 0 157276 0 0 0 0 1296470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334575 0 0 0 0 579368 0 0 0 0 631619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2263127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQLLNDMHVPFEMNALSAHR MGYG000002281_03334;MGYG000002549_04615;MGYG000001345_00584 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,2FMWN@200643|Bacteroidia,4AMDP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) 1.0 purE 1.0 - 1.0 5.4.99.18 1.0 ko:K01588 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R07405 1.0 RC01947 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 5-(carboxyamino)imidazole ribonucleotide mutase. N(5)-carboxyaminoimidazole ribonucleotide mutase. In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates.-!-In the absence of EC 6.3.2.6, the reaction is reversible.-!-The substrate is readily converted into 5-amino-1-(5-phospho-D- ribosyl)imidazole by non-enzymic decarboxylation. 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1- (5-phospho-D-ribosyl)imidazole-4-carboxylate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 0 0 0 383557 0 0 0 381029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489633 0 0 0 647883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105567 0 0 0 98422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92374 0 0 0 94123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQLLVYR MGYG000003074_00587;MGYG000004740_00273;MGYG000001617_02045 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,27K1G@186928|unclassified Lachnospiraceae 0.3333333333333333 186801|Clostridia 1.0 I 0.6666666666666666 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 306313 772105 0 480257 0 0 0 1408508 0 0 581849 617184 381024 0 0 0 0 0 0 419710 0 0 1403773 0 0 0 1108157 0 0 0 0 572298 0 0 333642 0 2064634 0 793041 1627627 0 1158838 0 1390994 1172931 1650526 937814 0 1015843 1190843 1249375 265784 0 0 1269247 0 0 745897 0 1445455 1300278 1578031 2187510 0 1136740 1332291 1305580 0 1167995 1772450 0 1895887 1499826 988847 915083 0 788608 1183663 0 706136 0 931587 733013 1181729 608120 0 814484 1020842 1010152 775017 0 0 803597 0 0 1016090 0 825938 961143 924432 1204176 0 1067127 791142 518974 0 1102590 1429616 0 735961 963897 757928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 973442 0 1207574 1574240 0 1009054 0 1451104 1255445 1877334 874836 0 418478 1669829 1439306 1247845 0 0 934282 0 0 1499449 0 2101495 1882566 1091223 1231897 0 2041892 904440 1044950 0 1272868 1515951 0 1482035 1068969 1341146 -AAQLNQEAVDNGLVR MGYG000002517_00279 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia 1.0 186801|Clostridia 1.0 V 1.0 PFAM VanW family protein 1.0 - 1.0 - 1.0 - 1.0 ko:K18346 1.0 ko01502,ko02020,map01502,map02020 1.0 M00651 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01504 1.0 - 1.0 - 1.0 - 1.0 G5,PG_binding_4,VanW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Vancomycin resistance;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 630393 0 0 0 0 0 0 0 806298 0 0 0 0 0 846774 0 0 0 0 0 449622 0 0 0 732164 817913 449981 0 0 0 0 0 0 0 0 824756 878886 0 447261 0 0 0 0 0 0 0 634179 0 0 0 0 0 692021 0 0 0 0 0 454662 0 0 0 534380 496174 633564 0 0 0 0 0 0 0 0 564854 817670 0 -AAQLVADGGYGHTSSLYINVNETEK MGYG000000142_00071 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401077 527510 333580 0 0 0 813973 505401 0 0 853392 0 0 0 0 0 0 0 0 659709 0 0 0 0 0 336189 712128 0 0 0 854722 495681 287197 480831 0 495656 338574 586918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQLVADGGYGHTSSLYVHPAETEK MGYG000001310_00117;MGYG000002772_01870;MGYG000000249_01522 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Naphthalene degradation;Pyruvate metabolism;Fatty acid degradation;Butanoate metabolism;Chloroalkane and chloroalkene degradation;Metabolic pathways;Tyrosine metabolism;Glycolysis / Gluconeogenesis;Degradation of aromatic compounds;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 346945 1166922 0 0 0 432243 440115 0 452196 0 0 666438 352484 315908 0 0 592898 1755770 517510 871359 0 0 0 410604 0 0 389305 0 292218 0 0 0 0 231707 0 0 1027764 0 703238 471137 0 0 0 452482 988169 0 1875458 0 0 2431219 1681605 943037 0 0 479281 267694 299086 351781 0 0 0 542269 0 0 595250 0 886639 0 0 0 0 0 0 0 843115 0 317862 190830 0 0 0 413465 0 0 443923 0 0 703877 381204 0 0 0 340970 317270 424350 388912 0 0 0 339219 0 0 312457 0 795465 0 0 0 0 444799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQM(Oxidation)AAETATK MGYG000002528_01864;MGYG000003215_00849;MGYG000000142_02038;MGYG000004055_01475;MGYG000000301_00188;MGYG000000171_01879;MGYG000002025_01287;MGYG000003500_00156;MGYG000004735_02050;MGYG000001338_02782;MGYG000004740_00893;MGYG000002286_01563;MGYG000002559_01476;MGYG000000532_01246;MGYG000001141_01291;MGYG000001564_01925;MGYG000000204_02185;MGYG000001637_00006;MGYG000003694_02453;MGYG000003422_00383;MGYG000000356_00499;MGYG000001456.1_01726;MGYG000000216_02331;MGYG000002670_00411;MGYG000000154_01812;MGYG000000139_02422;MGYG000000245_02664;MGYG000000136_02053;MGYG000001186_01087;MGYG000000201_02106;MGYG000002492_00401;MGYG000001493_03358;MGYG000000050_01197;MGYG000000028_01597;MGYG000000153_02068;MGYG000004879_02709 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia 0.5 186801|Clostridia 1.0 J 0.9444444444444444 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.6111111111111112 rpsK 0.6111111111111112 - 1.0 - 1.0 ko:K02948 0.6111111111111112 ko03010,map03010 0.9444444444444444 M00178,M00179 0.9444444444444444 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.9444444444444444 - 1.0 - 1.0 - 0.9444444444444444 Ribosomal_S11 0.6111111111111112 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.9444444444444444 none 1.0 0 0 0 0 707418 0 0 0 0 0 562463 0 0 316692 0 699104 0 1518904 0 504537 0 0 563612 0 0 0 0 711331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93466 0 0 0 0 0 192529 0 0 0 0 0 0 385509 0 0 0 0 228330 0 0 0 0 455398 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193971 0 0 0 0 0 301489 0 0 225847 0 333927 0 0 0 260937 0 0 118379 0 0 0 0 408256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 560890 0 0 0 0 0 346711 0 0 511913 0 444237 0 393631 0 580312 0 0 0 0 0 0 0 601147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278939 0 0 0 0 0 77171 0 0 277408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQM(Oxidation)AAQDC(Carbamidomethyl)AK MGYG000002721_02313;MGYG000001599_01826;MGYG000003420_01325;MGYG000001433_02301;MGYG000001345_04724;MGYG000002218_02495;MGYG000000781_00873;MGYG000003498_00774;MGYG000000696_01638;MGYG000002281_02250;MGYG000003164_01271;MGYG000001835_02485;MGYG000004763_00950;MGYG000003681_02077;MGYG000001370_01720;MGYG000001666_01381;MGYG000001378_05002;MGYG000001787_01778;MGYG000000013_02211;MGYG000001306_02685;MGYG000002935_01264;MGYG000000196_04014;MGYG000002561_02200;MGYG000001337_03864;MGYG000002470_01205;MGYG000001313_00049;MGYG000000054_03883;MGYG000001461_00429;MGYG000001789_00105;MGYG000000174_03501;MGYG000002418_00853;MGYG000000673_01669;MGYG000000273_00381;MGYG000000138_02864;MGYG000003693_00218;MGYG000002438_02233;MGYG000001780_04852;MGYG000003202_00871;MGYG000000044_02999;MGYG000000029_02814;MGYG000002560_00261;MGYG000002762_00888;MGYG000002455_03924;MGYG000001346_01494;MGYG000001871_02152;MGYG000000105_02030;MGYG000003233_00179;MGYG000000236_01762;MGYG000002291_02230;MGYG000004797_02000;MGYG000002275_02092;MGYG000002181_02223;MGYG000003701_04719;MGYG000003521_01403;MGYG000004748_03267;MGYG000001659_00171 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,2FRZD@200643|Bacteroidia,22XN9@171551|Porphyromonadaceae 0.5178571428571429 976|Bacteroidetes 1.0 J 0.5178571428571429 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.5178571428571429 rpsK 0.5178571428571429 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 0.5178571428571429 - 1.0 ko:K02948 0.5178571428571429 ko03010,map03010 0.5178571428571429 M00178,M00179 0.5178571428571429 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.5178571428571429 - 1.0 - 1.0 - 1.0 Ribosomal_S11 0.5178571428571429 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.5178571428571429 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362406 0 526700 0 0 0 0 279279 0 0 0 0 257246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 96242 0 0 0 0 350518 0 0 0 0 337948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73370 0 0 0 0 0 0 93551 0 0 0 0 101081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252011 0 320869 0 0 0 0 0 0 0 0 0 284597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164985 0 0 0 0 106787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQM(Oxidation)MVYR MGYG000000255_01556;MGYG000000205_02133 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,21YI4@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 387155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 863445 0 0 0 0 0 0 667146 1182298 577450 0 0 0 554643 0 0 0 0 0 0 0 0 0 0 0 427328 0 0 0 0 0 0 0 894438 0 658374 484721 0 0 0 0 0 0 0 0 0 637988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188903 0 0 0 0 0 0 0 0 0 0 0 156476 0 166258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQMAAEDC(Carbamidomethyl)AK MGYG000002293_00481;MGYG000003697_01443;MGYG000001056_02461;MGYG000003374_01465;MGYG000004629_00380 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,4ANYH@815|Bacteroidaceae 0.4 976|Bacteroidetes 1.0 J 0.6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.6 rpsK 0.6 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 0.6 - 1.0 ko:K02948 0.6 ko03010,map03010 0.6 M00178,M00179 0.6 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.6 - 1.0 - 1.0 - 1.0 Ribosomal_S11 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.6 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1219274 0 0 1043670 0 0 0 0 0 0 0 0 0 0 0 2491772 0 0 0 2009835 1701753 1705330 0 0 0 3139068 0 0 0 0 1561908 0 0 0 0 1518195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQMAAETAA(Ala->Thr)K MGYG000001315_01363;MGYG000001602_00406;MGYG000003486_01280;MGYG000003687_04935;MGYG000004699_00255;MGYG000003355_02337;MGYG000000164_02739;MGYG000002212_00566 domain d__Bacteria 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,268PI@186813|unclassified Clostridiales 0.5 186801|Clostridia 0.875 J 0.75 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.75 rpsK 0.75 - 0.875 - 1.0 ko:K02948 0.75 ko03010,map03010 0.75 M00178,M00179 0.75 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.75 - 1.0 - 1.0 - 0.75 Ribosomal_S11 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQMAAETAAK MGYG000001315_01363;MGYG000001602_00406;MGYG000003486_01280;MGYG000003687_04935;MGYG000004699_00255;MGYG000003355_02337;MGYG000000164_02739;MGYG000002212_00566 domain d__Bacteria 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,268PI@186813|unclassified Clostridiales 0.5 186801|Clostridia 0.875 J 0.75 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.75 rpsK 0.75 - 0.875 - 1.0 ko:K02948 0.75 ko03010,map03010 0.75 M00178,M00179 0.75 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.75 - 1.0 - 1.0 - 0.75 Ribosomal_S11 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.75 none 1.0 0 0 0 183416 0 717587 437603 1125690 0 1137170 735518 0 1167045 0 1144601 964473 0 582366 1338548 1451680 0 1187046 647947 706853 0 0 0 852222 0 0 0 0 0 0 1074082 951019 0 0 0 0 0 1061533 0 0 1407926 715072 0 498435 389781 0 664483 0 306710 550927 0 1156520 422287 974461 0 348916 948438 1226930 0 0 0 1057074 0 0 0 0 0 0 828949 901180 0 0 0 0 0 555430 0 0 0 796438 0 299287 0 0 609592 0 0 810194 0 449994 481892 679978 0 421045 477743 320485 0 0 0 249738 0 0 0 0 0 0 514821 0 0 0 0 0 0 490670 0 569452 466978 579223 0 349965 258751 0 478588 0 611171 983170 0 660477 480829 676829 0 1010665 0 843526 0 0 0 1175227 0 0 0 0 0 0 455340 120551 0 0 0 0 0 0 0 0 245718 240178 0 0 0 0 0 0 0 214642 0 302020 0 0 0 312904 259692 0 0 0 0 0 0 0 0 0 0 0 0 561517 0 0 -AAQMAAETATK MGYG000002528_01864;MGYG000003215_00849;MGYG000000142_02038;MGYG000004055_01475;MGYG000000301_00188;MGYG000000171_01879;MGYG000002025_01287;MGYG000003500_00156;MGYG000004735_02050;MGYG000001338_02782;MGYG000004740_00893;MGYG000002286_01563;MGYG000002559_01476;MGYG000000532_01246;MGYG000001141_01291;MGYG000001564_01925;MGYG000000204_02185;MGYG000001637_00006;MGYG000003694_02453;MGYG000003422_00383;MGYG000000356_00499;MGYG000001456.1_01726;MGYG000000216_02331;MGYG000002670_00411;MGYG000000154_01812;MGYG000000139_02422;MGYG000000245_02664;MGYG000000136_02053;MGYG000001186_01087;MGYG000000201_02106;MGYG000002492_00401;MGYG000001493_03358;MGYG000000050_01197;MGYG000000028_01597;MGYG000000153_02068;MGYG000004879_02709 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia 0.5 186801|Clostridia 1.0 J 0.9444444444444444 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.6111111111111112 rpsK 0.6111111111111112 - 1.0 - 1.0 ko:K02948 0.6111111111111112 ko03010,map03010 0.9444444444444444 M00178,M00179 0.9444444444444444 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.9444444444444444 - 1.0 - 1.0 - 0.9444444444444444 Ribosomal_S11 0.6111111111111112 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.9444444444444444 none 1.0 2565808 2014826 2389548 2756310 2986034 2047751 0 2225747 0 2466990 2787534 0 0 0 0 2639415 2135088 3482009 0 2474224 0 2060368 2768065 1492389 0 2066784 1979704 3120132 2141104 0 1957911 2151835 2395874 0 2251344 2028142 2291789 2174041 1479067 2740019 1051216 1706093 1698943 894478 0 1584797 0 1417425 1377634 0 0 0 0 1632828 1230537 4301859 0 1409673 0 1078439 2977740 2036096 0 1211088 1884116 4692428 2329234 0 3136275 2027779 1710761 0 1478905 1649186 1247312 1705346 967723 2141650 1710698 865564 670541 1441108 0 1067529 0 837865 608382 0 0 0 0 1594685 1409148 1571076 0 872471 0 1869893 1690759 1110632 0 1569248 1399316 2414534 1387208 0 684018 1960833 2269222 0 1057127 751729 1133138 1652841 2680277 2374583 1665916 1689645 2092485 1121572 0 2200196 0 1842027 1806241 0 0 0 0 2749199 2042991 2080543 0 2607402 0 547198 534445 0 0 160756 3269869 2043581 2657255 0 3298784 1895828 1485354 0 0 1420782 2879721 2088433 3255992 2842710 1886040 2742014 1996447 2108843 0 3169030 0 2995626 2810635 0 0 0 0 1976496 3354282 1250199 0 2071171 0 2143196 1834115 2763070 0 4281422 3826168 1701501 2887961 0 2018708 2255690 3081686 0 3932402 4470075 0 0 -AAQMAAETTAK MGYG000001511_00066 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Bacillales_E|f__Massilibacteriaceae|g__Massilibacterium|s__Massilibacterium senegalense|m__MGYG000001511 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,1ZFIU@1386|Bacillus 1.0 91061|Bacilli 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1316322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2863875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2968526 2709500 -AAQMAAQDC(Carbamidomethyl)AK MGYG000002721_02313;MGYG000001599_01826;MGYG000003420_01325;MGYG000001433_02301;MGYG000001345_04724;MGYG000002218_02495;MGYG000000781_00873;MGYG000003498_00774;MGYG000000696_01638;MGYG000002281_02250;MGYG000003164_01271;MGYG000001835_02485;MGYG000004763_00950;MGYG000003681_02077;MGYG000001370_01720;MGYG000001666_01381;MGYG000001378_05002;MGYG000001787_01778;MGYG000000013_02211;MGYG000001306_02685;MGYG000002935_01264;MGYG000000196_04014;MGYG000002561_02200;MGYG000001337_03864;MGYG000002470_01205;MGYG000001313_00049;MGYG000000054_03883;MGYG000001461_00429;MGYG000001789_00105;MGYG000000174_03501;MGYG000002418_00853;MGYG000000673_01669;MGYG000000273_00381;MGYG000000138_02864;MGYG000003693_00218;MGYG000002438_02233;MGYG000001780_04852;MGYG000003202_00871;MGYG000000044_02999;MGYG000000029_02814;MGYG000002560_00261;MGYG000002762_00888;MGYG000002455_03924;MGYG000001346_01494;MGYG000001871_02152;MGYG000000105_02030;MGYG000003233_00179;MGYG000000236_01762;MGYG000002291_02230;MGYG000004797_02000;MGYG000002275_02092;MGYG000002181_02223;MGYG000003701_04719;MGYG000003521_01403;MGYG000004748_03267;MGYG000001659_00171 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,2FRZD@200643|Bacteroidia,22XN9@171551|Porphyromonadaceae 0.5178571428571429 976|Bacteroidetes 1.0 J 0.5178571428571429 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.5178571428571429 rpsK 0.5178571428571429 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 0.5178571428571429 - 1.0 ko:K02948 0.5178571428571429 ko03010,map03010 0.5178571428571429 M00178,M00179 0.5178571428571429 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.5178571428571429 - 1.0 - 1.0 - 1.0 Ribosomal_S11 0.5178571428571429 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.5178571428571429 none 1.0 1130244 696104 1504601 1180829 1245185 1074689 1806373 1200075 1205097 1084413 2409909 1536450 1356605 1552707 1544199 1440286 1107624 1127828 2119709 1686410 1393504 1376286 1430579 1333562 1640769 1312181 1075297 1390159 1251538 868182 1103259 913871 1280077 1447644 0 1540421 1234659 1008504 674304 370384 550609 1038770 764406 614004 766754 982425 765442 959445 1299408 1114224 964142 1044080 1027719 1015824 653575 1908734 742063 1085363 1028729 829901 3806366 579968 782458 996062 890139 2694860 745667 895497 574114 828991 837139 859561 0 755886 667723 453896 196411 301599 426390 238523 401591 388931 374375 288381 324481 0 473006 379044 341451 313973 278765 469849 487224 951621 229765 393413 285729 393582 722301 240509 143367 231086 252494 640141 372455 261326 332268 207413 227705 103749 0 381112 269270 295500 939149 846571 819540 665696 1113313 1036581 932377 870960 781664 763158 928890 929500 673023 712618 697682 1128989 765759 889789 929347 897262 585765 934066 281535 672993 861015 992819 808922 877068 887429 855009 1065403 720940 968670 693488 0 613954 632303 1149974 385124 99680 204955 164243 521719 372225 392919 368357 471576 0 482892 553822 363506 0 0 521073 449666 1160589 383884 536334 522111 301646 1084739 378625 353200 669072 0 715943 269701 474880 0 0 0 317416 0 492768 0 359231 -AAQMALK MGYG000001378_03103 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG0702@1|root,COG0702@2|Bacteria,4NHVQ@976|Bacteroidetes,2FPT0@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 GM 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2287940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQMDEWFSGK MGYG000002293_00078;MGYG000003697_02025 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the transketolase family 1.0 tkt 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 625170 667549 1143606 0 752328 1119208 779339 774545 571080 0 1028104 603120 972054 804858 541138 842409 0 4979567 0 474904 585366 1384152 4216380 1087299 854425 702146 0 2377379 741399 0 704100 847877 1068548 882973 739202 920259 740503 1035359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQMDEWFSGKAPK MGYG000002293_00078;MGYG000003697_02025 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the transketolase family 1.0 tkt 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Biosynthesis of ansamycins;Carbon metabolism;Metabolic pathways;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 303248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 607210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 535835 0 0 0 261621 392189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1697140 0 916016 1463788 0 0 0 0 1271970 0 0 0 0 1253720 0 3828035 0 0 0 1586045 6690145 1115868 0 0 0 3252328 0 0 983047 914788 1379390 878624 0 0 0 1328786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQMMVYR MGYG000000255_01556;MGYG000000205_02133 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,21YI4@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 1821722 1471590 964787 1219691 1520823 1175095 1270037 2230314 1199953 1773312 799084 1514818 1239825 1844144 1086278 913312 1707221 0 1139055 1580728 1631896 1097563 0 865872 1409876 1176136 1482320 0 1617247 1146252 751102 1016057 899602 2114495 1745711 1173246 1193740 928232 9233281 4019175 3850881 9182695 4653383 3395421 7721904 6589189 4832787 8782110 3724250 5559993 6325017 6125121 6145353 3996749 6210416 0 4735968 6156440 6252037 3146747 0 3720803 6656714 5587761 7059989 0 7379580 4851558 3641418 3493734 5159258 9555270 6139784 7851110 5387136 3895614 1523231 1036576 815195 1084753 604215 744629 1207785 1719919 1252232 1567118 694094 707947 1003847 1383950 1337745 961955 1216222 0 1511579 1490850 1100565 1222554 0 920713 1825472 1520778 1678089 0 1382077 697946 640771 1295166 1129432 2475740 980228 1178176 1139075 1017188 703399 2214189 365477 391458 291137 2713610 404710 558839 368646 444261 145711 314989 366191 356423 396141 360901 214291 0 172375 552923 570973 460782 0 1653191 329891 227512 515586 0 237460 158905 1941037 2327882 2804203 280013 394645 335703 412159 194213 407193 909052 701974 1161446 738541 792188 1670874 1323264 876068 1023892 501759 1260618 487276 1014646 908985 1099497 618727 0 706057 731977 543334 1422303 0 1050514 888552 282476 282735 0 1161898 491896 1063396 690667 911018 1988637 800944 646722 562862 939320 -AAQNDPAVQEAVK MGYG000001300_02007 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3WGDW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate 1.0 glmM 1.0 - 1.0 5.4.2.10 1.0 ko:K03431 1.0 ko00520,ko01100,ko01130,map00520,map01100,map01130 1.0 - 1.0 R02060 1.0 RC00408 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoglucosamine mutase. - The enzyme is involved in the pathway for bacterial cell-wall peptidoglycan and lipopolysaccharide biosyntheses, being an essential step in the pathway for UDP-N-acetylglucosamine biosynthesis.-!-The enzyme from Escherichia coli is activated by phosphorylation and can be autophosphorylated in vitro by alpha-D-glucosamine 1,6- bisphosphate, which is an intermediate in the reaction, alpha-D- glucose 1,6-bisphosphate or ATP.-!-It can also catalyze the interconversion of alpha-D-glucose 1-phosphate and alpha-D-glucose 6-phosphate, although at a much lower rate. alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways 1.0 none 1.0 0 922600 975583 695198 0 574129 270323 0 0 0 322667 0 989507 0 0 0 556205 0 0 831281 0 692909 0 550886 520061 0 0 0 0 0 0 0 1246250 0 0 0 0 1032219 0 1010015 981098 1152244 0 831800 1180608 0 0 0 502136 0 618190 0 0 0 1140858 0 0 864846 0 551908 0 706526 1142738 0 0 0 0 0 0 0 1216040 0 0 0 0 867654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 914699 1423604 941494 0 1106388 1530413 0 0 0 893166 0 910485 0 0 0 992736 0 0 1003154 0 1454747 0 968361 945245 0 0 0 0 0 0 0 1138142 0 0 0 0 1398457 0 0 0 135707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166852 0 0 0 0 0 -AAQNIIPSSTGAAK MGYG000001692_02867 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Aeromonadaceae|g__Aeromonas|s__Aeromonas dhakensis|m__MGYG000001692 1.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1Y3YS@135624|Aeromonadales 1.0 135624|Aeromonadales 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5273777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQNVSGPLVSR MGYG000002494_03842 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,3WXW5@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 T 1.0 Two component signalling adaptor domain 1.0 cheV 1.0 - 1.0 - 1.0 ko:K03415 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW,Response_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1404534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1730217 0 1269527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQPIVDSVADIKK MGYG000000362_01314 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-115|s__CAG-115 sp003531585|m__MGYG000000362 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1955491 0 0 0 0 2565700 0 0 0 0 2391636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7436200 0 0 0 0 6657158 0 0 0 0 7639864 0 0 0 0 0 0 0 0 0 0 -AAQPLMTILHPEK MGYG000000042_02028 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900066445|m__MGYG000000042 1.0 COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FMQ9@200643|Bacteroidia,4AK7H@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Alpha-1,2-mannosidase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_125,Glyco_hydro_92 1.0 3.2.1.-|3.2.1.114 1.0 GH92 1.0 GH92 1.0 GH92 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 483952 0 0 0 0 803116 0 0 0 0 511777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 173778 0 0 0 0 203860 0 0 0 0 224423 0 0 0 0 0 0 0 0 0 0 -AAQQAAKPEPQEAR MGYG000000262_00560 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0305@1|root,COG0305@2|Bacteria,1W6Y2@1239|Firmicutes,25M5M@186801|Clostridia,25ZAD@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 L 1.0 Participates in initiation and elongation during chromosome replication 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DnaB_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 96553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 970851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQQEVTK MGYG000002517_01169 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 associated with various cellular activities 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1770446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1106546 0 -AAQSAAETAAK MGYG000001255_02107;MGYG000000258_00308;MGYG000002926_00510;MGYG000001673_01419;MGYG000001733_00006;MGYG000001300_02188;MGYG000004487_00995;MGYG000003899_00640;MGYG000000022_02014;MGYG000003166_00785;MGYG000002619_02360;MGYG000004475_01165;MGYG000000392_01434;MGYG000002143_01912;MGYG000004525_00990;MGYG000002272_00477;MGYG000002720_00255;MGYG000002794_00566;MGYG000002984_00006;MGYG000003494_00371;MGYG000000195_02107;MGYG000002156_01377;MGYG000002545_01114;MGYG000003937_00240;MGYG000002224_01634 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3WIYT@541000|Ruminococcaceae 0.56 186801|Clostridia 0.92 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.92 rpsK 0.92 - 0.92 - 0.92 ko:K02948 0.92 ko03010,map03010 0.92 M00178,M00179 0.92 - 0.92 - 0.92 br01610,ko00000,ko00001,ko00002,ko03011 0.92 - 1.0 - 1.0 - 1.0 Ribosomal_S11 0.92 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 0.92 0.92 0.92 0.92 Ribosome 0.92 none 1.0 1410632 944333 2151332 2439288 1042322 1468068 1348160 1278577 2073665 1936116 0 1358248 1789592 1799213 0 1820975 2036160 5532901 2725844 2911264 1247009 1612537 3542350 1361417 2119054 2114919 1756339 3437852 1190915 1379732 1709844 1429154 1977814 2618401 0 1819269 1747976 1760419 1068634 584542 747520 1682424 652572 629358 1576241 678698 900465 278760 0 1013361 790717 1372293 0 984612 1037863 2654766 958186 1109699 437660 935566 5129418 1015731 963233 1070372 1284904 5465265 415104 876270 1424863 689141 674815 986893 0 924874 939470 553065 391577 663647 566187 718398 526487 564816 379731 674296 821263 502800 0 439390 612116 662222 0 484002 486798 345620 515868 557539 684916 442216 1108295 610666 546073 541935 629249 1887115 673360 343867 514387 391001 486802 662480 0 752427 721311 898856 2147808 1942029 2923409 2306588 2205150 2491737 2420887 1628695 1902703 1876838 0 2326452 1750040 1780465 0 2576075 2083280 6199485 2242825 2546108 824164 3138202 1745392 2934815 2066779 3562941 2501743 7606404 1371903 1905512 3088286 1667729 2776552 1630043 0 744423 1767376 2994539 143900 187101 289243 122928 170929 246824 438571 0 335649 0 0 206060 235346 0 0 131316 441543 1099568 0 204653 113288 170026 1144267 214488 381713 421145 0 302472 207206 351761 269911 0 0 493549 0 236020 316574 238762 -AAQSIAVAR MGYG000002953_03277;MGYG000002670_01511;MGYG000002727_00924;MGYG000002057_01748;MGYG000003215_01534;MGYG000004482_00909;MGYG000002974_01391;MGYG000002720_01849;MGYG000001616_02334;MGYG000001617_02042;MGYG000001637_02269;MGYG000003694_00877;MGYG000000153_01463;MGYG000001502_00825;MGYG000003589_00853;MGYG000002492_00657;MGYG000004276_00829;MGYG000002707_01243;MGYG000000489_01023;MGYG000002445_02272;MGYG000002926_00108;MGYG000000280_01473;MGYG000002143_01933;MGYG000000377_01679;MGYG000004487_00561;MGYG000004784_00845;MGYG000000389_02151;MGYG000004271_00231;MGYG000001683_01598;MGYG000000245_02019;MGYG000000271_02104;MGYG000001186_01723;MGYG000004475_01257 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.3939393939393939 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.5151515151515151 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 2032219 1612500 1413707 0 2042516 2008429 2130035 1695060 1803800 1557675 1617550 1721372 0 2174980 2992291 1817295 1614438 5313921 0 2237730 0 1995154 5914570 2244041 2291868 2000788 0 4000217 0 0 1974864 2516213 1676224 2642096 2095931 1955583 2171852 1951756 117213 0 0 0 0 113204 0 0 0 157915 0 77246 0 0 243452 0 166702 1143204 0 0 0 0 1757700 0 0 0 0 1319423 0 0 0 0 157792 237055 249053 0 0 0 14016177 7962418 31053892 0 10394872 4861346 10164478 13327893 15087475 8361289 9181063 8743922 0 12412850 13169796 6978567 5787434 5888304 0 16021489 0 4622361 5517065 5128636 14200968 9893028 0 5896970 0 0 7618525 4856262 23098517 14865474 6769201 12620461 14575450 22489584 1307070 3344343 3797974 0 2938941 3717689 2066975 1871661 2229380 3394719 2539307 2137101 0 2027606 1695850 3033197 2374651 3936770 0 2352576 0 3708744 1738297 5435195 986293 973261 0 8451091 0 0 5263212 2106533 3989498 959995 1870976 1054045 1447617 6514429 755013 230469 440020 0 557616 472097 334909 514496 420079 709736 310093 1891614 0 603216 256748 311943 636800 3647553 0 667001 0 407257 3065336 500928 481940 688951 0 2293746 0 0 558183 569197 303674 690513 398086 849056 532378 341372 -AAQSIAVAR(Arg->Gln)DLK MGYG000000489_01023 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp900548765|m__MGYG000000489 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1503996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQSIGEPGTQLTLR MGYG000001666_00329;MGYG000001789_00145;MGYG000004797_04274;MGYG000000196_03983;MGYG000001431_01172;MGYG000003681_02045;MGYG000000243_01979;MGYG000001346_01525;MGYG000002438_02330;MGYG000002478_00805;MGYG000004757_00585;MGYG000004885_00605 domain d__Bacteria 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 0.5833333333333334 976|Bacteroidetes 0.9166666666666666 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 0.9166666666666666 2.7.7.6 1.0 ko:K03046 0.9166666666666666 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 0.9166666666666666 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 594479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 794417 0 0 0 0 0 0 0 0 0 0 733852 0 860044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1190321 0 0 0 0 0 0 0 0 0 0 934838 0 1173250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1149289 0 0 0 0 0 0 0 0 0 0 1101279 0 388491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513953 0 0 0 0 0 0 0 0 0 0 596082 0 723828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 538018 0 0 0 0 0 0 0 0 0 0 458324 0 -AAQSLAVAQDLK MGYG000001714_01774 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus_A|s__Coprococcus_A catus|m__MGYG000001714 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1242749 0 0 0 0 0 0 0 0 0 0 0 1335588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQSLAVAR MGYG000000489_01023;MGYG000002727_00924;MGYG000000245_02019;MGYG000002926_00108;MGYG000001689_03867;MGYG000003589_00853;MGYG000002492_00657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.42857142857142855 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 0.5714285714285714 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17110773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQSLAVGR MGYG000000262_02231 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 1140199 120207 169907 1305288 0 196005 532231 292015 0 98495 0 191437 181564 0 272210 1129156 592980 0 249090 533035 931867 147591 0 1076113 0 1066037 0 0 152565 1106948 854417 929257 542031 242886 156778 704910 1083449 578219 1728604 1786101 297064 195848 0 0 1180516 1506799 0 1583356 800295 1125087 688061 0 1059208 994338 1316333 0 84377 114932 1373414 2754867 0 1984157 0 1002580 0 0 1865682 82125 658505 1416071 1170970 1588082 1544029 1489394 1194631 837957 16385881 13776458 4454818 18591290 0 7899655 3728369 13041083 0 11690465 3720563 6221767 10064239 0 16814088 8036640 6598185 0 16005431 19206828 12924718 10959143 0 3984414 0 12106244 0 0 1707522 11981055 2190249 8517618 7554942 21036522 15690008 5884340 12232534 3224218 2722144 2021173 649832 2369923 0 1128785 1859496 523456 0 1800842 1222629 630187 810855 0 3320698 1962110 2145980 0 2179051 2985577 800768 1158732 0 1529535 0 372159 0 0 1587833 2195859 1638455 1416352 1186171 1397821 676914 2155410 2520692 1077410 1865903 1946888 3269491 0 0 2705510 1800436 1587400 0 3114488 2802465 2356724 835861 0 1800971 2228939 3407114 0 2098945 1278282 2512619 1837073 0 2119394 0 3291894 0 0 565420 1711883 2814637 440439 2326822 2164023 1280128 4473857 3073285 2864416 -AAQSLGVIHELVEEHGIDR MGYG000000223_02388 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,3VP0M@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 - 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQSVAVAR MGYG000000204_00804;MGYG000002528_02664;MGYG000000028_00940;MGYG000001500_00694;MGYG000002517_00540 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 0.6 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.8 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 1.0 none 1.0 765142 400581 522578 647632 1459810 393725 300728 613459 709582 973259 1216284 682522 897195 1132099 2216879 1410317 739748 822177 1891209 1242500 489646 1050346 332476 260004 1274753 862522 706706 211307 211089 442116 0 1047199 734877 632124 1034242 495080 658975 568074 217893 3435208 270182 195119 534856 265006 222271 278334 304602 0 334516 0 823834 0 0 83541 126651 320659 197942 331321 158634 0 110962 289155 376051 131358 324955 0 787405 451992 0 1003774 453344 485934 0 602351 263422 330096 4835450 16510914 5764147 3084168 1310985 8594960 4408071 9682659 5909793 8453572 3871305 6177886 5634108 6134161 10089428 6298234 5711279 679325 15743626 11813397 5986567 15567155 1557207 5206407 11678665 9351556 6225384 2039669 11498503 9484967 0 12866136 7653031 18701078 5988966 8955755 6391591 4729626 15447188 8436571 9300498 19101488 14143040 7072790 8716501 14400009 18926664 15531878 10296689 6448842 3981026 21729255 22063768 8986113 22127000 1038436 18376238 23760605 4113159 5108827 0 10319843 14655832 9965113 15402753 3068946 15700731 23258543 0 6127195 6322251 4924963 16541026 9550568 18017210 13582249 1222223 1482407 1829043 1333650 364514 1330727 1227028 470637 1285887 1084967 2123608 6558154 1504260 1015691 1770433 675749 1419324 173978 407604 751962 691045 855220 0 1477063 1675860 1258829 1665789 315079 403169 634620 0 2486554 4080104 480508 764397 1594806 1622231 2226847 -AAQSVAVGK MGYG000000205_02136;MGYG000003486_02525;MGYG000000217_01337;MGYG000000255_01552;MGYG000000325_01142 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,4BWBU@830|Butyrivibrio 0.4 186801|Clostridia 1.0 I 0.8 Thiolase, C-terminal domain 0.8 thlA 0.8 - 1.0 2.3.1.9 0.8 ko:K00626 0.8 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 0.8 M00088,M00095,M00373,M00374,M00375 0.8 R00238,R01177 0.8 RC00004,RC00326 0.8 ko00000,ko00001,ko00002,ko01000,ko04147 0.8 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 0.8 - 1.0 - 1.0 - 1.0 - 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 0.8 0.8 0.8 0.8 Two-component system;Pyruvate metabolism;Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Benzoate degradation;Fatty acid degradation;Valine, leucine and isoleucine degradation;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Fatty acid metabolism;Lysine degradation;Biosynthesis of secondary metabolites;Tryptophan metabolism;Microbial metabolism in diverse environments;Propanoate metabolism;Terpenoid backbone biosynthesis 0.8 none 1.0 0 0 0 0 0 415103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 555972 0 420537 596588 0 0 0 0 0 0 0 0 434146 0 0 0 0 0 0 0 0 0 1085466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 786163 0 1050021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 593922 0 0 1534594 0 0 0 0 0 0 0 0 2745162 0 0 0 0 0 0 0 0 0 1086143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1529234 0 2354323 469298 0 0 0 0 0 0 0 0 317923 0 0 0 0 0 0 0 0 0 168366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153688 0 468417 367745 0 0 0 0 0 0 0 0 405919 0 0 0 0 -AAQT(Thr->Ser)AAETAAK MGYG000002835_01005 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter sp900543115|m__MGYG000002835 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,268PI@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 882146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQTE(Glu->Phe)SFGYNTDEIVSSDIVGMR MGYG000002528_00367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 422669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342231 0 192164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 240558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQTESFGYN(Deamidated)TDEIVSSDIVGM(Oxidation)R MGYG000002528_00367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055150 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQTESFGYNTD(Cation_Na)EIVSSDIVGMR MGYG000002528_00367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 186294 0 0 0 398483 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459981 0 0 0 0 0 0 0 0 0 257936 0 0 0 0 0 0 0 1318936 0 0 0 691067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479150 0 1119474 0 0 0 0 0 0 0 718635 0 0 0 0 0 0 0 1446885 0 0 0 891323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1828563 0 688358 0 0 0 0 0 0 0 2026938 0 0 0 0 0 0 0 754231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQTESFGYNTDE(Cation_Na)IVSSDIVGMR MGYG000002528_00367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1333442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQTESFGYNTDEIVSSDIVGM(Oxidation)R MGYG000002528_00367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 439497 0 0 0 0 0 505459 0 0 0 0 0 0 231194 0 0 0 0 0 0 0 0 0 0 785633 0 0 0 427363 0 0 0 0 0 0 0 0 0 369686 0 0 0 0 0 264833 0 746563 0 0 0 0 352280 0 0 358796 0 0 0 0 0 0 0 2949297 0 0 0 1116501 0 0 0 0 0 0 0 0 0 601983 0 0 845687 0 0 2310322 0 1181007 0 0 0 0 1688857 0 0 2200905 0 660331 0 0 0 0 0 512660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220217 0 0 0 0 1168468 0 0 364606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132293 0 0 0 0 -AAQTESFGYNTDEIVSSDIVGMR MGYG000002528_00367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 822034 493852 0 646160 692037 0 172224 0 407005 636802 584145 588030 547124 345915 447032 290348 624690 246548 289724 0 1008438 506279 503917 329689 302152 451001 587612 1278574 344283 644890 0 349801 541011 428921 0 325269 470760 328179 4358352 597550 0 1173652 2178743 405192 497109 0 0 333515 230815 466531 414030 472633 559183 559341 2429061 321895 593618 357200 1434154 1161641 3843184 0 503596 610523 1556494 1197073 0 1812015 2269701 506657 510500 442807 0 338940 666420 1427501 7985931 3942797 0 1189387 3541209 1821590 1899002 0 1589630 1931258 1991204 1773213 1150202 1423732 2069185 1827228 224724 2643491 1219974 1523158 7105346 1062308 6020535 1866199 4967184 1918701 1131707 5671203 1373055 1290862 15284681 3696592 2239718 3185140 0 2570983 4460768 695806 3609266 2211919 0 4219346 1274858 1977341 999894 0 192673 1648175 929349 4323153 1408257 359574 2385869 1544384 230337 464220 2183493 0 196190 0 9038751 1043044 708004 983140 0 19153534 356789 8909423 6599473 5435504 245510 250657 0 358714 5466316 0 307438 179110 0 0 210706 0 177241 0 227847 0 212219 0 0 0 156236 273886 0 0 198876 0 0 3638464 567738 0 2429353 0 394787 0 335648 402504 0 345805 0 0 0 0 284742 -AAQTGEIGDGR MGYG000000196_04260;MGYG000001313_01813 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0347@1|root,COG0347@2|Bacteria,4NQG9@976|Bacteroidetes,2FSGK@200643|Bacteroidia,4AQX6@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 Belongs to the P(II) protein family 1.0 glnB 1.0 - 1.0 - 1.0 ko:K04751 1.0 ko02020,map02020 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001 1.0 - 1.0 - 1.0 - 1.0 P-II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 969075 0 0 0 0 858696 0 0 0 0 494149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1269414 0 0 0 0 593957 0 0 0 0 909527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQTIEVATR MGYG000000022_02855 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG2211@1|root,COG2211@2|Bacteria,1TRYR@1239|Firmicutes,24FE0@186801|Clostridia,3WN0N@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 MFS/sugar transport protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MFS_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1801121 0 0 0 0 1909981 0 0 0 0 1841172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 728111 0 2380522 0 0 0 0 0 0 0 0 0 2651493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 843024 0 0 0 0 601712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278588 0 1378921 0 0 0 0 2139482 0 0 0 0 2185252 0 0 0 0 0 0 0 0 0 0 -AAQVAMDVTTK MGYG000000164_00686 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 1014435 803240 0 0 0 975500 1356694 1688632 1525443 0 0 0 0 1100011 1662815 0 0 0 1429063 2236244 1051342 853447 0 607037 1803556 1261581 0 0 0 1130081 0 0 0 0 0 0 1027467 0 385879 0 0 0 0 0 118865 218490 610313 0 0 0 0 0 0 0 0 0 0 286208 468215 0 0 0 228514 344217 0 0 0 625238 0 0 0 0 0 0 348629 0 0 0 0 0 0 0 366909 0 0 0 0 0 0 0 300412 0 0 0 132107 0 287696 0 0 0 0 0 0 0 0 268161 0 0 0 0 0 0 0 0 0 0 0 0 0 260396 328979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447617 0 0 0 0 0 0 0 0 -AAQVEEIAK MGYG000003921_01311;MGYG000001300_02638;MGYG000003166_01200 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WICR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 - 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3220972 0 0 0 0 0 0 0 0 0 2933553 0 0 0 0 0 2262362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733082 1872635 0 0 0 772336 0 0 0 0 570918 0 0 0 0 0 1789065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1910705 5342279 0 0 0 1977485 0 0 0 0 1920282 0 0 0 0 0 578793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2839663 3157465 0 0 0 1204036 0 0 0 0 2364617 0 0 0 0 0 1579532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189040 0 0 0 0 1094802 0 0 0 0 1124862 0 0 0 0 0 0 0 0 0 0 -AAQVSYNYPAETDEHSYGIDVQNANKK MGYG000004642_00725 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,36FMV@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 PFAM L-carnitine dehydratase bile acid-inducible protein F 1.0 hadA 1.0 - 1.0 2.8.3.24 1.0 ko:K20882 1.0 - 1.0 - 1.0 R11462 1.0 RC00014,RC00137 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_transf_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 (R)-2-hydroxy-4-methylpentanoate CoA-transferase. - The enzyme, characterized from the bacterium Peptoclostridium difficile, participates in an L-leucine fermentation pathway.-!-The reaction proceeds via formation of a covalent anhydride intermediate between a conserved aspartate residue and the acyl group of the CoA thioester substrate. (R)-2-hydroxy-4-methylpentanoate + 4-methylpentanoyl-CoA = (R)-2-hydroxy- 4-methylpentanoyl-CoA + 4-methylpentanoate. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 908494 0 811018 0 0 1088980 1200301 869630 977847 1069221 0 0 0 0 1262681 0 1145541 0 803829 0 0 1058509 0 1360104 951613 1206677 1150246 0 1245285 0 0 0 860442 1249386 0 1130211 856160 645562 -AAQVTQAHQSLTLDELYQM(Oxidation)MR MGYG000002494_03340 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1461@1|root,COG1461@2|Bacteria,1MXIB@1224|Proteobacteria,1RPJ7@1236|Gammaproteobacteria,3WY50@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Dak2 1.0 dhaL 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 2.7.1.121 1.0 ko:K05879 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECUMN_1333.ECUMN_1495 1.0 Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 0 0 0 383993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 993036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQVTQAHQSLTLDELYQMMR MGYG000002494_03340 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1461@1|root,COG1461@2|Bacteria,1MXIB@1224|Proteobacteria,1RPJ7@1236|Gammaproteobacteria,3WY50@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Dak2 1.0 dhaL 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 2.7.1.121 1.0 ko:K05879 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECUMN_1333.ECUMN_1495 1.0 Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism;Metabolic pathways 1.0 none 1.0 0 0 0 0 0 188163 0 0 0 0 0 0 0 0 255956 0 0 0 0 0 0 321150 0 460213 0 0 0 0 0 0 0 0 0 237055 0 0 0 0 0 0 0 0 0 38618208 0 0 0 0 0 0 0 0 40348475 0 0 0 0 0 0 53533934 0 79106129 0 0 0 0 0 0 0 0 0 14055986 0 0 0 0 0 0 0 0 0 264625 0 0 0 0 0 0 0 0 433988 0 0 0 0 0 0 426350 0 4618766 0 0 0 0 0 0 0 0 0 862657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 561295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 173988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5967308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQWQNFHK MGYG000001300_01291 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 106320 0 164920 0 0 0 0 75787 0 0 0 0 0 0 0 0 169952 0 0 0 287756 0 0 0 0 307094 0 0 0 0 171592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178529 0 0 87008 54688 0 0 150376 0 0 0 0 0 0 0 0 64591 0 0 0 0 102379 0 0 0 0 0 0 0 0 73565 0 0 0 0 0 0 0 1210687 0 948105 1007593 1616620 0 0 956795 0 0 0 0 0 0 0 1441362 1757019 0 0 1036095 378372 1992894 0 0 0 2111284 0 0 1706851 0 1063450 0 0 0 0 1772903 0 0 534020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQWTGGGIIFAPTPR MGYG000000002_00881 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A faecis|m__MGYG000000002 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQYDGLEIMDR MGYG000002552_00779;MGYG000000187_01833;MGYG000000078_00956;MGYG000004317_00105;MGYG000000562_00476 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira 1.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,25UY8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 COG0524 Sugar kinases, ribokinase family 1.0 - 1.0 - 1.0 2.7.1.45 1.0 ko:K00874 1.0 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 1.0 M00061,M00308,M00631 1.0 R01541 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2-dehydro-3-deoxygluconokinase. KDG kinase. The enzyme shows no activity with 2-dehydro-3-deoxy-D-galactonate. cf. EC 2.7.1.178. 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D- gluconate + ADP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Metabolic pathways;Carbon metabolism;Microbial metabolism in diverse environments 1.0 none 1.0 1454764 1913722 1708187 2509436 1800435 2260589 1425161 1994955 1890247 2372062 1955713 2239923 1504279 1864742 1941963 0 0 5838094 1826052 1634135 1459186 1634156 5393156 2307262 2155103 1693004 1746796 5583137 2093888 1931620 1992031 2129405 1528987 1931219 1776924 1641498 1728429 1743929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1110941 0 0 0 0 1190135 0 0 0 0 1130278 0 0 0 0 0 0 0 0 0 0 803659 348611 498499 551988 680210 591079 475948 558455 529901 385376 583741 742161 618813 745540 542094 0 0 2967241 416002 435096 419471 429030 2885097 617203 334820 377167 770374 3169534 796826 778503 707513 394980 562413 698902 525377 454871 514261 709931 743084 883286 417532 814142 1043248 517020 772256 566417 770263 762555 767048 516643 1057426 754065 297662 0 0 2260983 436296 495252 0 1837522 1385441 2197793 252466 373205 838572 2576777 1307696 641705 709717 287734 388654 380989 624121 582362 555962 412918 0 0 291026 0 0 0 407668 287598 589224 984198 362492 294496 508944 297166 0 0 0 2908085 1294798 0 583570 0 2918661 270022 807982 726206 0 3159319 814171 0 0 793601 566874 1340586 871027 320423 1160617 0 -AAQYDTLR MGYG000000074_02643 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,2FN0U@200643|Bacteroidia,22US1@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 Acetohydroxy acid isomeroreductase, catalytic domain 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Metabolic pathways;Valine, leucine and isoleucine biosynthesis;Biosynthesis of secondary metabolites;Pantothenate and CoA biosynthesis;Biosynthesis of amino acids 1.0 none 1.0 336531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456804 0 0 0 0 0 0 0 0 0 0 484756 0 239240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308462 0 0 0 0 0 0 0 0 0 0 319765 0 586262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502387 0 0 0 0 0 0 0 0 0 0 579912 0 386064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1213156 0 0 0 0 0 0 0 0 0 0 947967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQYDVAEAISLVK MGYG000000271_03296 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQYDVAEAISLVKK MGYG000000271_03296 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQYINAIDKNR MGYG000002293_00752 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0446@1|root,COG0446@2|Bacteria,4P1DZ@976|Bacteroidetes,2G0CQ@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2607249 0 0 0 0 4119502 0 0 0 0 1476892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQYLVYAAAC(Carbamidomethyl)KK MGYG000001356_00009 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter sp000177015|m__MGYG000001356 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WI1F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Carbon metabolism;Valine, leucine and isoleucine degradation;Fatty acid degradation;Butanoate metabolism;Fatty acid metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1997165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2571513 0 0 0 0 0 0 0 0 0 -AAQYPGIEVVPLQVK MGYG000002478_04323;MGYG000000243_00993 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4656@1|root,COG4656@2|Bacteria,4NIS7@976|Bacteroidetes,2FMAQ@200643|Bacteroidia,4AM9Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4_10,Fer4_17,Fer4_7,Fer4_8,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 617838 0 269022 0 0 0 0 710871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1368345 0 462719 0 0 0 0 644415 0 0 0 0 584665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564250 0 690076 0 0 0 0 573746 0 0 0 0 683145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 648498 0 1448566 0 0 0 0 1149905 0 0 0 0 1097790 0 0 0 0 0 0 0 0 0 0 -AAQYPGIEVVPLQVKYPQGGEK MGYG000002478_04323;MGYG000000243_00993;MGYG000004797_00718 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4656@1|root,COG4656@2|Bacteria,4NIS7@976|Bacteroidetes,2FMAQ@200643|Bacteroidia,4AM9Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4_10,Fer4_17,Fer4_7,Fer4_8,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQYVAAH(Oxidation)PGEVC(Carbamidomethyl)PAK MGYG000002494_00621 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,3WV8Q@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 O 1.0 C-terminal domain of 1-Cys peroxiredoxin 1.0 ahpC 1.0 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.0 1.11.1.15 1.0 ko:K03386 1.0 ko04214,map04214 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 1-cysPrx_C,AhpC-TSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 and 1.11.1.29. - - - 1.0 1.0 1.0 1.0 Apoptosis - fly 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1484660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAQYVAAHPGEVC(Carbamidomethyl)PAK MGYG000002494_00621 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,3WV8Q@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 O 1.0 C-terminal domain of 1-Cys peroxiredoxin 1.0 ahpC 1.0 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.0 1.11.1.15 1.0 ko:K03386 1.0 ko04214,map04214 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 1-cysPrx_C,AhpC-TSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 and 1.11.1.29. - - - 1.0 1.0 1.0 1.0 Apoptosis - fly 1.0 none 1.0 0 191966 0 0 377889 593769 0 0 0 266798 341981 86658 0 0 0 448183 407050 0 420102 0 255429 498776 0 385911 314288 138577 109217 0 488841 0 0 810761 416035 524058 0 0 345864 303925 1930113 10003453 3402235 0 5820234 9503010 0 0 0 2162398 1885160 1445144 0 0 0 4198554 4497588 0 2964502 0 2801743 13069367 0 8676565 1650221 2212673 1708601 0 3612438 0 0 4611185 4498411 1830894 0 0 1922889 3018309 559812 103925 498192 0 295053 507445 0 0 0 0 0 199632 0 0 0 222019 0 0 563001 0 221729 0 0 311060 0 715950 355462 0 121769 0 0 0 0 170744 0 0 355694 0 131315 331515 802496 0 311926 0 0 0 0 0 436347 339807 0 0 0 484528 227177 0 0 0 0 753921 0 0 405196 194615 257195 0 239642 0 0 221543 0 252559 0 0 108043 0 0 213041 654205 0 0 384328 0 0 0 289019 211533 357884 0 0 0 0 258094 0 0 0 145808 270777 0 397658 295981 365944 0 0 0 0 0 0 0 275359 0 0 255269 225422 -AAQYVASHPGEVC(Carbamidomethyl)PAK MGYG000002506_04802;MGYG000002323_01203;MGYG000000093_02223;MGYG000002513_00687;MGYG000000235_00832;MGYG000002515_02417;MGYG000000337_00350;MGYG000000107_01732 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,3WV8Q@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 O 1.0 C-terminal domain of 1-Cys peroxiredoxin 1.0 ahpC 1.0 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.0 1.11.1.15 1.0 ko:K03386 1.0 ko04214,map04214 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 1-cysPrx_C,AhpC-TSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 and 1.11.1.29. - - - 1.0 1.0 1.0 1.0 Apoptosis - fly 1.0 none 1.0 2439390 1546120 1652330 2173035 1256901 3364395 2895668 2697925 1731199 2259637 0 1423695 1102941 1568129 1970192 1316300 0 0 1804618 1744218 2150743 4114819 0 4214758 1962855 1557134 2269503 0 0 1963837 1455536 1816818 1630182 2305207 2227470 1809405 1610801 1580567 1458785 1213813 1724955 1095436 1324276 2757149 1247957 2174623 1805802 2097886 0 1046431 1446884 1395732 1573733 1378774 0 0 1385022 1277478 1392391 3267885 0 2372619 1229587 1462606 1388136 0 0 1613625 1363150 1132972 1629906 1422387 1933391 1053807 1858198 1710378 2383869 2701485 2829071 1205988 3024008 4592692 3595397 3034423 2357082 2515158 0 2152183 2391123 2683125 2138114 2649919 0 0 2540014 2196209 2319373 4270533 0 4175729 2533913 2162590 2070506 0 0 2468134 2017243 0 2985140 3201336 3106084 2288369 1892177 2731908 1963553 1763230 1849328 1994064 1465808 1826776 2586088 1943017 1373666 2011617 0 1263846 1618815 1653996 1365982 1454257 0 0 1131613 1342345 2179425 1627487 0 758814 2196775 1692731 1915991 0 0 1330564 575009 1033513 1506089 3339788 3131504 2654704 1495921 1108073 323159 411627 240721 560802 230810 450439 417455 428012 345235 283616 0 306045 207760 655652 293599 708267 0 0 368552 340406 200339 0 0 293610 265977 305767 0 0 0 289032 308974 479003 230963 468037 513717 359622 313652 389771 -AAQYVASHPGEVC(Delta_H(6)C(3)O(1))PAK MGYG000002506_04802;MGYG000002323_01203;MGYG000000093_02223;MGYG000002513_00687;MGYG000000235_00832;MGYG000002515_02417;MGYG000000337_00350;MGYG000000107_01732 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,3WV8Q@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 O 1.0 C-terminal domain of 1-Cys peroxiredoxin 1.0 ahpC 1.0 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.0 1.11.1.15 1.0 ko:K03386 1.0 ko04214,map04214 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 1-cysPrx_C,AhpC-TSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 and 1.11.1.29. - - - 1.0 1.0 1.0 1.0 Apoptosis - fly 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 229901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 551885 0 273979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1427888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1493626 0 852125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AARIPEKR MGYG000002970_00265;MGYG000001709_01326;MGYG000001567_00563;MGYG000003266_00519;MGYG000002961_01431;MGYG000004681_00352 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4CXT4@84998|Coriobacteriia 0.6666666666666666 84998|Coriobacteriia 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 - 1.0 - 1.0 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AARLFAK MGYG000001602_02095;MGYG000002279_02008;MGYG000000142_01058;MGYG000001338_02036;MGYG000000002_01844;MGYG000000212_02086 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3XZ4K@572511|Blautia 0.5 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AARPEDLER MGYG000003022_00085;MGYG000003352_00212 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2VNMJ@28216|Betaproteobacteria 1.0 28216|Betaproteobacteria 1.0 E 1.0 peptidase 1.0 - 1.0 - 1.0 3.4.17.11 1.0 ko:K01295 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glutamate carboxypeptidase. carboxypeptidase G2. Produced by pseudomonads, Flavobacterium sp. and Acinetobacter sp.-!-Its ability to hydrolyze pteroyl-L-glutamate (folic acid) has led to its use as a folate-depleting, antitumor agent.-!-Belongs to peptidase family M20A. Release of C-terminal glutamate residues from a wide range of N-acylating moieties, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 96095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1211264 1256963 996506 1310826 0 1655562 0 0 1007303 859868 0 1605034 1238390 0 0 0 0 1192327 0 1211423 0 916209 0 0 0 0 0 0 0 1136215 1181566 1371271 0 1092058 0 1029222 0 0 1183981 811446 828344 1067790 0 1519443 0 0 475223 815248 0 1009313 887332 0 0 0 0 845349 0 882155 0 1065307 0 0 0 0 0 0 0 899080 649653 802431 0 923125 0 682566 0 0 0 382043 320423 0 0 205469 0 0 0 364750 0 217507 715333 0 0 0 0 169923 0 0 0 0 0 0 0 0 0 0 0 0 0 100417 0 137060 0 283174 0 0 0 188584 152018 78763 0 358360 0 0 0 468122 0 324181 137848 0 0 0 0 99513 0 106724 0 270395 0 0 0 0 0 0 0 205471 0 387585 0 286491 0 71452 -AARPQDHSQKVN MGYG000002506_02960 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 376789 0 0 0 0 0 224069 0 0 0 0 0 0 0 0 0 474386 0 0 0 0 0 0 0 0 333516 0 0 0 0 0 0 0 0 0 0 383793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 43367 0 272028 0 0 0 0 0 595664 0 0 0 0 0 0 0 0 0 202908 0 0 0 0 0 0 0 0 529167 0 0 0 0 0 0 0 0 0 0 414707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAS(Deoxy[S](Ser->Ala)GNIIPSSTGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10606038 0 0 0 0 0 0 0 0 0 0 0 9440436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2611269 0 0 0 0 0 0 0 0 2638975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAS(Deoxy[S](Ser->Ala)SESFGYNEDQIVSSDVIGMR MGYG000002641_00563;MGYG000000195_01135 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2692770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1264239 0 0 0 0 0 0 0 0 0 1106253 0 0 0 0 0 0 0 0 0 0 393762 0 1307830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351520 950226 0 0 0 0 0 0 0 0 0 0 0 1957803 0 0 0 270873 0 0 0 0 522183 0 0 0 0 0 0 0 383625 0 0 0 546452 0 0 0 0 0 400473 0 0 0 0 0 0 0 0 0 0 0 0 665858 0 -AAS(Formyl[S](Ser->Asp)GNIIPSSTGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAS(Methyl[S](Ser->Thr)DLEFSK MGYG000003681_02191;MGYG000001661_01238;MGYG000002561_00276;MGYG000004899_00435;MGYG000001313_00261;MGYG000004185_02017;MGYG000000224_00588 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2214163 1888826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1555823 0 0 0 0 2141909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 792745 -AAS(Methyl[S](Ser->Thr)SESFGYNEDQIVSSDVIGMR MGYG000002641_00563;MGYG000000195_01135 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 927361 0 0 0 0 0 0 0 0 0 0 0 1306068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 773345 0 0 0 0 0 0 0 0 0 0 0 0 1038668 0 0 0 0 0 0 0 0 0 0 799765 0 0 0 0 0 0 0 0 0 0 0 915795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683687 0 0 0 0 0 0 0 0 0 0 465896 598045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AAS(Octanoyl)GNIIPSSTGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2906958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASAAEC(Carbamidomethyl)IQLISQGERPLVR MGYG000001300_02023 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,3WGRN@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 phosphoribosylformylglycinamidine synthase 1.0 purL 1.0 - 1.0 6.3.5.3 1.0 ko:K01952 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04463 1.0 RC00010,RC01160 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C,GARS_A,GARS_C,GARS_N,GATase_5,PurS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphoribosylformylglycinamidine synthase. phosphoribosylformylglycinamidine synthetase. - ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D- ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D- ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism;Biosynthesis of secondary metabolites;Metabolic pathways 1.0 none 1.0 457286 0 0 269331 0 0 321987 0 0 0 0 201154 0 294268 0 0 0 0 402993 0 0 0 0 0 0 269968 0 0 0 0 0 0 0 0 0 385156 256069 0 598493 0 0 747076 0 0 1013959 0 0 0 0 807513 0 890882 0 0 0 0 1127484 0 0 0 0 0 0 1033765 0 0 0 0 0 0 0 0 0 860265 1045634 0 180648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122567 0 0 0 0 165234 0 0 0 0 0 0 0 0 0 0 0 0 0 329840 0 0 0 0 0 0 0 0 0 0 188605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASAAGLSIHVPFAPGR MGYG000002506_03648 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0685@1|root,KOG0564@2759|Eukaryota 1.0 2759|Eukaryota 1.0 E 1.0 methylenetetrahydrofolate reductase (NAD(P)H) activity 1.0 MTHFR1 1.0 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.0 1.5.1.20,3.6.4.12 1.0 ko:K00297,ko:K10901 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko03440,ko03460,map00670,map00720,map01100,map01120,map01200,map01523,map03440,map03460 1.0 M00295,M00377,M00414 1.0 R01224,R07168 1.0 RC00081 1.0 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 1.0 - 1.0 - 1.0 - 1.0 BT1,DEAD,DUF1712,EamA,Helicase_C,Homoserine_dh,Hormone_recep,MTHFR,RecQ_Zn_bind,peroxidase,zf-C4 1.0 - 1.0 - 1.0 - 1.0 AA0 1.0 methylenetetrahydrofolate reductase [NAD(P)H]. | DNA helicase. MTHFR. A flavoprotein (FAD).-!-The enzyme catalyzes the reversible conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, playing an important role in folate metabolism by regulating the distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis.-!-This enzyme, characterized from Protozoan parasites of the genus Leishmania, is unique among similar characterized eukaryotic enzymes in that it lacks the C-terminal allosteric regulatory domain (allowing it to catalyze a reversible reaction) and uses NADH and NADPH with equal efficiency under physiological conditions. cf. EC 1.5.1.53, EC 1.5.1.54, and EC 1.5.7.1.-!-Formerly EC 1.1.1.68, EC 1.1.1.171, EC 1.1.99.15 and EC 1.7.99.5. | DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA.-!-Some of them unwind duplex DNA with a 3' to 5' polarity, other show 5' to 3' polarity or unwind DNA in both directions.-!-Some helicases unwind DNA as well as RNA.-!-May be identical with EC 3.6.4.13. (1) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH. (2) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH. | ATP + H2O = ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 Fanconi anemia pathway;Carbon metabolism;Homologous recombination;Carbon fixation pathways in prokaryotes;Metabolic pathways;Antifolate resistance;One carbon pool by folate;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 811107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASAEEAAALVK MGYG000000133_01784 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes;Microbial metabolism in diverse environments;Carbon metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410741 332286 278235 310652 0 212698 376955 325991 0 0 0 552205 0 494995 0 0 0 1671649 343906 0 557170 267665 1887105 0 0 286994 363988 1917859 275912 0 0 459242 138948 0 0 478106 635509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 576322 0 0 0 0 0 0 0 0 0 0 3756344 2159542 2427905 4833489 0 1579850 6686302 3596784 2786724 5067893 2547367 3615527 1700718 7132133 5127457 1678628 3399622 556979 3144088 0 5942705 1620280 706489 1698726 4406586 3053663 4130280 1041031 6400104 1358401 1680567 1901850 3007461 4211155 3105438 3773216 2678881 1607205 -AASAELVAK MGYG000004642_00011 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,36EA6@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 - 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_10,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432731 0 0 0 0 0 0 0 0 0 0 588882 0 0 0 0 691101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3615191 0 0 0 0 0 350135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1088297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASAGDFR MGYG000000212_00999 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XZ7S@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Respiratory-chain NADH dehydrogenase 51 Kd subunit 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 171168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 678142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 526673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2181653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASAMVPGDHGTTYGGNPLVTAGAK MGYG000000179_03148 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,26803@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 argD 1.0 - 1.0 2.6.1.11,2.6.1.17 1.0 ko:K00821 1.0 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00028,M00845 1.0 R02283,R04475 1.0 RC00006,RC00062 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 acetylornithine transaminase. | succinyldiaminopimelate transaminase. succinylornithine aminotransferase. | succinyldiaminopimelate transferase. Also acts on L-ornithine and N(2)-succinyl-L-ornithine. 2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L- glutamate 5-semialdehyde. | 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (S)-2- succinylamino-6-oxoheptanedioate + L-glutamate. 1.0 1.0 1.0 1.0 2-Oxocarboxylic acid metabolism;Arginine biosynthesis;Metabolic pathways;Lysine biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 345949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1773966 0 0 0 0 0 0 0 0 0 0 0 0 2404934 1771101 0 0 0 0 1168126 0 0 0 0 0 1556881 0 0 2296975 0 0 0 0 0 0 0 1389630 0 -AASANIIPSSTGAAK MGYG000004642_01190 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,36DD0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025251 0 1112522 0 0 0 0 0 0 830037 818665 0 0 0 0 0 802965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291802 0 0 0 0 0 0 319464 0 0 0 0 0 0 0 0 246157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASAPAAPAAN(Deamidated)GGIPK MGYG000000133_00167 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3WS7A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Glucose dehydrogenase C-terminus 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1434018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASAPAAPAANGGIPK MGYG000000133_00167 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3WS7A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Glucose dehydrogenase C-terminus 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASDEILQLSR MGYG000000489_01608;MGYG000002517_00264 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,26B8C@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 NT 1.0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). 1.0 - 1.0 - 1.0 - 1.0 ko:K03406 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 4HB_MCP_1,HAMP,MCPsignal,dCache_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis;Two-component system 1.0 none 1.0 320495 0 0 448345 256443 393852 721435 210187 152911 594628 0 424576 0 111030 452857 0 454604 0 654612 412461 434620 383697 0 1524518 452263 315524 0 0 0 229801 0 0 0 383510 1119583 405864 1613419 0 220255 0 0 0 0 227451 379670 0 0 0 0 0 0 0 592279 710592 0 0 246619 0 0 0 0 0 277952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350982 0 320775 0 0 0 0 0 0 0 0 261352 0 0 0 304471 197842 0 0 120125 0 0 0 0 0 440996 0 0 0 556449 374777 0 0 0 3492107 0 0 3455960 1528469 1583039 2117097 3028920 3372948 2002997 0 1478838 0 3829811 3558856 1426412 2467724 0 2684698 2981834 2070271 529989 0 535588 3735700 2914181 3881565 0 0 2841711 0 0 0 2379520 3383240 3570071 2994082 0 998852 0 0 357059 472722 913003 1157936 735834 1037423 1400892 0 948820 0 1274920 1564409 801439 934327 0 1148221 817929 1427222 540067 0 960349 1247784 909467 1146755 0 0 918033 0 0 0 1091177 970766 1211367 1478980 0 -AASDEYN(Deamidated)WDLNYGEIAK MGYG000003372_02246;MGYG000002477_02450;MGYG000002494_03646 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,3X1E7@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH 1.0 gnd 1.0 GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.0 1.1.1.343,1.1.1.44 1.0 ko:K00033 1.0 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 1.0 M00004,M00006 1.0 R01528,R10221 1.0 RC00001,RC00539 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 1.0 6PGD,NAD_binding_2 1.0 - 1.0 - 1.0 - 1.0 GT30 1.0 phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating). | phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating). 6-PGDH. | phosphogluconic acid dehydrogenase. Highly specific for NAD(+).-!-The enzyme catalyzes both the oxidation and decarboxylation of 6-phospho-D-gluconate.-!-In the bacterium Methylobacillus flagellatus the enzyme participates in a formaldehyde oxidation pathway. cf. EC 1.1.1.44. | The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions.-!-Highly specific for NADP(+). cf. EC 1.1.1.343. 6-phospho-D-gluconate + NAD(+) = CO2 + D-ribulose 5-phosphate + NADH. | 6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Glutathione metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASDEYNWDLNYGEIAK MGYG000003372_02246;MGYG000002477_02450;MGYG000002494_03646 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,3X1E7@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH 1.0 gnd 1.0 GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.0 1.1.1.343,1.1.1.44 1.0 ko:K00033 1.0 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 1.0 M00004,M00006 1.0 R01528,R10221 1.0 RC00001,RC00539 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 1.0 6PGD,NAD_binding_2 1.0 - 1.0 - 1.0 - 1.0 GT30 1.0 phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating). | phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating). 6-PGDH. | phosphogluconic acid dehydrogenase. Highly specific for NAD(+).-!-The enzyme catalyzes both the oxidation and decarboxylation of 6-phospho-D-gluconate.-!-In the bacterium Methylobacillus flagellatus the enzyme participates in a formaldehyde oxidation pathway. cf. EC 1.1.1.44. | The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions.-!-Highly specific for NADP(+). cf. EC 1.1.1.343. 6-phospho-D-gluconate + NAD(+) = CO2 + D-ribulose 5-phosphate + NADH. | 6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Glutathione metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585681 1144980 1263178 0 1071547 1820122 1345141 0 0 1372033 0 0 0 1200420 0 0 1546407 0 1893751 0 2270429 2165745 0 1849622 2297793 812758 0 0 2222233 2139435 702274 1008424 1417656 1026657 0 849755 766138 1183453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASDGPMAQTK MGYG000002993_01302 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-170|s__CAG-170 sp000432135|m__MGYG000002993 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,2N71Q@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 886651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASDGPMAQTR MGYG000004526_00639;MGYG000003096_01037;MGYG000002116_00788;MGYG000002720_00092;MGYG000002084_01252;MGYG000004482_01535;MGYG000004196_01067;MGYG000001824_01594;MGYG000003686_02367;MGYG000004276_00122;MGYG000001502_01278;MGYG000002143_01659;MGYG000003266_00955;MGYG000004475_00887;MGYG000002715_01695;MGYG000001086_01249;MGYG000002794_01318;MGYG000001757_01274;MGYG000004508_00787 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,2N71Q@216572|Oscillospiraceae 0.631578947368421 186801|Clostridia 0.8947368421052632 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 3314085 1981239 2031533 2581764 2208705 2405409 4154388 2734557 2949696 2555779 1915338 0 1951942 3172784 2784583 1933372 1954164 2105349 2417194 2200754 2499487 1966996 2442607 3066948 2926867 2751837 0 3119138 2374776 1599534 2070470 1751844 2259290 3896923 2505323 3171915 3117286 2174275 0 1102791 310797 0 180252 189800 111409 299080 276741 149203 0 0 131894 218558 400468 215156 217220 3154057 216098 103870 316528 245150 0 200598 287158 144258 0 350640 248326 331574 392354 108215 229169 0 0 0 264292 331286 461013 532871 730186 436799 942747 926405 831503 786397 1324358 439269 1179436 0 699463 946018 607126 979974 983233 870064 1130515 848943 616999 546879 667840 713695 716444 630093 0 613012 0 720520 649211 620946 689973 1257723 570132 869352 527285 667772 2000283 1762594 2344059 2354483 1617561 1676545 1817481 3461926 2101062 2064816 1958191 0 1500839 1836146 2973427 1430171 1940753 2924460 1687765 1965408 900700 1912507 1857555 1732162 2792355 2868934 0 2657169 2497451 1531209 1786808 2363718 2085575 2608028 2315518 2094748 2844650 1814748 129428 0 249239 0 467486 384598 885386 821292 0 318183 381589 0 176156 522265 658490 464068 517937 0 343940 378033 336229 107870 160675 1720063 876518 560200 0 228579 0 488276 0 175917 0 832732 660575 243744 530644 279773 -AASDGPMPQTR MGYG000001881_00748;MGYG000003022_00748;MGYG000001008_02651;MGYG000000349_00457;MGYG000004288_00862;MGYG000003022_00735;MGYG000000223_03134;MGYG000001299_01777;MGYG000003352_00730;MGYG000000930_01271 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,3VNVP@526524|Erysipelotrichia 0.5 526524|Erysipelotrichia 0.5 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 290563 262107 391973 103910 0 349057 0 248888 0 210074 202759 326896 357098 183860 0 299521 113303 0 0 0 352550 295369 0 334874 0 227183 199192 0 380343 399179 205021 288317 285474 0 299863 0 256395 0 994521 964325 1306487 1211580 1115270 1115009 0 2314105 0 1192343 1094404 958001 911395 1002561 0 832053 1015905 0 0 0 1283604 1189954 0 781782 0 0 890538 0 1315729 3017601 808110 1148551 1173603 1139929 2345346 0 1012488 922376 615202 1077375 829155 799685 1387090 1068755 0 1111964 0 607514 724463 741006 529615 733902 0 637918 1124765 0 0 0 1072969 1011374 0 1143744 0 777458 467732 0 988169 1752290 944528 1375085 543192 662034 960711 0 403051 789427 367365 819114 402658 490611 643800 654189 0 693776 0 499999 451362 450527 439323 310319 0 411910 712843 0 0 0 410530 552982 0 429300 0 431620 430338 0 644582 445182 347699 1415647 637093 496624 859814 0 511081 624771 169111 0 189733 526880 287846 0 0 204383 0 182976 116998 238873 379432 157040 0 0 0 0 0 0 175824 331124 0 521159 0 168908 0 0 25064 157882 219398 244229 135557 427095 173078 0 0 467508 -AASDKGYLGYIHIGEANR MGYG000000028_01658 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus_A|m__MGYG000000028 1.0 COG1082@1|root,COG1082@2|Bacteria,1UYHR@1239|Firmicutes,25C7S@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016854,GO:0016857,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050897 1.0 5.1.3.30,5.1.3.31 1.0 ko:K18910 1.0 - 1.0 - 1.0 R10817,R10818 1.0 RC03111,RC03283 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 D-psicose 3-epimerase. | D-tagatose 3-epimerase. DPEase. | L-ribulose 3-epimerase. The enzyme is highly specific for D-psicose and shows very low activity with D-tagatose (cf. EC 5.1.3.31). | The enzymes isolated from the bacteria Pseudomonas cichorii, Pseudomonas sp. ST-24, Rhodobacter sphaeroides and Mesorhizobium loti catalyze the epimerization of various ketoses at the C3 position, interconverting D-fructose and D-psicose, D-tagatose and D-sorbose, D-ribulose and D-xylulose, and L-ribulose and L-xylulose.-!-The specificity depends on the species. D-allulose = keto-D-fructose. | (1) keto-D-tagatose = keto-D-sorbose. (2) D-allulose = keto-D-fructose. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1232703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASDLEFA(Ala->Ser)K MGYG000003367_01391;MGYG000004876_01285;MGYG000002455_01371;MGYG000001780_02426;MGYG000003363_00089;MGYG000001370_01765;MGYG000001346_02094;MGYG000001461_00206 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2426938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3599070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2222596 0 0 0 0 3323983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASDLEFAK MGYG000003367_01391;MGYG000004876_01285;MGYG000002455_01371;MGYG000001780_02426;MGYG000003363_00089;MGYG000001370_01765;MGYG000001346_02094;MGYG000001461_00206 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1042533 661419 753124 1027768 895250 1075331 1008388 920143 383352 859546 2196415 1468210 628230 1011275 690266 5828173 988301 873480 1100459 1019833 871585 795863 978030 1072068 498013 1060984 888405 740100 843860 1197375 1007622 415388 865583 1252193 947244 816919 444317 912033 1533086 831860 1279930 1093933 1345213 1078220 931761 1205153 726660 1193118 1123670 2929666 510317 1067176 989294 976709 689681 442795 1006554 807084 1246429 1091777 746845 621885 854686 1128371 1171801 433263 823183 826403 485890 1357767 1196526 1192589 1327746 1258625 870429 1135343 1437423 923397 1383703 1459401 2371283 1655989 1984119 1302005 1674267 1356068 3745383 1616445 1265591 1535746 1202866 1760630 1634143 3226429 5052384 1336735 1492004 1640207 3243221 2054397 1155735 1265909 1203253 2629218 1705445 1677748 1648615 1307326 937963 621207 1114057 2214289 1227920 981198 1932639 949690 1959720 1358515 1726020 1559637 1466099 1654573 1345991 1536962 1740217 2416718 998469 1217430 1347856 1569945 1416754 899175 1755108 1065902 1108894 1256721 974604 1010283 3167185 1433638 1312008 1284915 752619 1740939 977571 1398512 1857436 1856078 1580108 1863168 1425515 1852776 984887 674723 862162 1029559 1629240 1260551 646776 1271795 1347694 867899 4395359 1394187 1517842 620818 960102 882028 962271 3089715 728982 1265384 551853 871072 2162166 1042697 1008839 967369 599427 2098340 1004079 1570687 366286 1273635 493188 1377659 455413 756244 1159676 975775 -AASDLEFSK MGYG000003681_02191;MGYG000001661_01238;MGYG000002561_00276;MGYG000004899_00435;MGYG000001313_00261;MGYG000004185_02017;MGYG000000224_00588 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1440758 1401173 1247833 1263301 255144 979071 1527862 1531598 1087183 1215577 791037 469928 942560 1170826 0 1310408 980269 691040 1200667 1174097 1141242 965148 332900 545907 0 1573750 1380114 469015 1292989 214921 474923 1420606 891776 1473649 1573394 1196041 1532569 766045 3280718 1604643 2323765 3307998 1719648 0 2549427 3258424 3511987 4296557 1837341 3273170 0 3541451 0 1683480 2931808 1793610 2975398 2902680 3098187 2022488 2534462 1767155 0 3793749 3160664 2406865 2561766 2816090 1559289 2429169 2141877 3289405 3729278 3479315 3424368 3347054 3237585 2014083 3706616 2985687 3573743 0 4999032 2984951 4300042 3351381 3236930 2545432 2207468 3295650 0 2155793 3269043 12305286 2250872 2388163 3142276 2502269 9646747 4000605 0 3279874 2826259 7516190 3736309 3712161 3874306 2290345 2223997 2494404 3287410 4649833 3724069 0 1638298 1302185 1745776 1693062 1471644 1711442 2140357 1614218 1969003 1779902 1516208 1851791 2148525 1821900 0 2112252 1771197 1374140 2237396 1931607 1270209 1697910 583345 1621823 0 2002435 1712881 1234270 2556580 1688979 1596175 1387902 1395430 1601892 1989034 2194271 1763310 1613264 444706 0 0 359187 0 209552 267761 476476 358145 0 182071 250657 133140 281946 0 258425 377411 1464707 206854 295220 479312 404903 879936 281753 0 237444 278008 306734 333167 358080 194978 0 449482 432755 324791 347263 159283 352593 -AASDVEGVYK MGYG000002485_02066;MGYG000004828_01510 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG1302@1|root,COG1302@2|Bacteria,37AEJ@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 S 1.0 Asp23 family, cell envelope-related function 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Asp23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3353560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASEAATEAAK MGYG000000242_00891 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,21Z0Q@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 K 1.0 PFAM regulatory protein GntR HTH 1.0 - 1.0 - 1.0 - 1.0 ko:K00375 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2,GntR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1379857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASEAVKDAALSC(Carbamidomethyl)DQFFVNHR MGYG000002323_00765;MGYG000002506_04304 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,3XMCP@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 ribosomal protein 1.0 rpsB 1.0 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 670486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641241 0 847829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400191 0 142235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 945693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697498 0 783162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASEAVKDAANSC(Carbamidomethyl)DQFFVNHR MGYG000002494_03066;MGYG000002477_04469 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,3XMCP@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 ribosomal protein 1.0 rpsB 1.0 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742173 901228 739285 0 814364 1406544 0 0 0 903372 0 0 0 0 0 0 768619 0 0 0 939727 2268271 0 1520630 912572 599640 0 0 1095884 0 0 731632 651658 0 0 746762 567104 720848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASEEYNWDLNYGEIAK MGYG000002506_01508 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,3X1E7@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH 1.0 gnd 1.0 GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.0 1.1.1.343,1.1.1.44 1.0 ko:K00033 1.0 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 1.0 M00004,M00006 1.0 R01528,R10221 1.0 RC00001,RC00539 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 1.0 6PGD,NAD_binding_2 1.0 - 1.0 - 1.0 - 1.0 GT30 1.0 phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating). | phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating). 6-PGDH. | phosphogluconic acid dehydrogenase. Highly specific for NAD(+).-!-The enzyme catalyzes both the oxidation and decarboxylation of 6-phospho-D-gluconate.-!-In the bacterium Methylobacillus flagellatus the enzyme participates in a formaldehyde oxidation pathway. cf. EC 1.1.1.44. | The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions.-!-Highly specific for NADP(+). cf. EC 1.1.1.343. 6-phospho-D-gluconate + NAD(+) = CO2 + D-ribulose 5-phosphate + NADH. | 6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Carbon metabolism;Glutathione metabolism;Metabolic pathways;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 728176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 839637 0 453202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 708646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 714690 0 608531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 971925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 734535 0 849289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASEFEALR MGYG000002717_02115;MGYG000001661_02103;MGYG000001313_03171;MGYG000000098_00636;MGYG000000054_02931;MGYG000000196_02287;MGYG000003681_00141;MGYG000004763_00640;MGYG000001346_00856 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 0.8888888888888888 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 0.8888888888888888 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 446351 182559 0 639102 0 573033 629955 626874 193209 0 730905 0 682125 429191 0 0 633421 0 469533 0 0 755810 0 389448 0 478489 0 0 227084 607755 401065 0 0 0 0 774955 442931 0 1296139 773889 1415331 1533000 1199985 1006170 1040344 1381243 1663589 0 1039894 0 767292 1323029 0 0 1230672 0 1049202 0 0 1127176 0 810509 0 1747467 0 0 1234754 1179590 964764 0 1383100 0 0 1321753 1773786 1596493 960885 761283 2023326 1995368 2132375 1653192 2348611 1089678 2071149 0 1698601 0 1369019 1540940 0 0 1584945 0 1251131 0 0 929472 0 1732240 0 1505670 0 0 1508804 1645485 2289251 0 1048036 0 0 2041367 1903453 1690485 1274974 760864 586606 1034863 929161 581166 800052 792309 1237402 0 570251 0 878194 790118 0 0 649386 0 683194 0 0 712793 0 562286 0 1616101 0 0 774452 901412 525092 0 354567 0 0 1428110 1086648 761293 0 0 0 0 0 0 0 829756 1024224 0 786837 0 983253 0 0 0 0 0 0 0 0 0 0 0 0 935365 0 0 0 1324729 0 0 0 0 0 0 219920 0 -AASEFEALRLETEASGK MGYG000002717_02115;MGYG000001313_03171;MGYG000000098_00636;MGYG000000054_02931;MGYG000000196_02287;MGYG000000105_02390;MGYG000003681_00141;MGYG000001346_00856 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 296792 0 132940 547900 329843 0 0 478910 0 482489 671464 489638 227630 361015 0 0 463217 0 281665 209733 327518 204545 0 473620 416988 461094 388618 0 487456 687629 465374 389725 251222 394199 483774 350797 399016 286350 721214 0 672489 1027963 778371 589044 0 964656 0 842535 857292 1285285 615200 791370 0 0 714971 0 527372 856759 642168 687504 0 462587 640073 722662 824361 0 419357 860635 252039 912647 558932 613682 890171 687469 785301 750039 662725 0 1038295 945828 995647 913593 0 735033 0 886730 1447706 1165925 638403 823609 0 0 761112 0 819507 995595 896904 579618 0 834180 823632 1246184 652128 0 977183 884413 946687 615719 483588 819213 621176 1179335 761293 928661 713729 0 715795 671222 481009 514012 0 591739 0 522323 527337 858471 567891 566429 0 0 574638 0 656075 499330 993887 541211 0 521754 592211 969896 596842 0 384793 690359 533042 767524 521888 858008 688676 712231 826329 453601 0 0 271305 112781 0 376115 0 280507 0 0 342317 163676 691504 181166 0 0 248115 0 0 350144 200295 420285 0 96073 198796 197110 383748 0 306651 426429 134582 362017 0 622124 410984 209576 330648 266826 -AASEFETLR MGYG000000243_02183 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 1762054 0 3382317 1763870 2775228 1793480 1672727 0 1616535 1381961 1558843 1645076 0 1739656 0 1907835 1887353 0 1694971 0 1635914 1510892 0 2261328 0 1409945 1623092 0 1630444 1761711 3148955 1976300 3214189 2096968 1752990 1858343 1559359 3735184 776080 0 1014064 244857 856544 362571 465431 0 796672 0 309176 0 0 470831 0 805541 660336 0 354830 0 968638 523930 0 371991 0 807694 665020 0 0 845652 680688 0 944405 654730 1169674 658424 0 0 0 0 274344 186121 385360 240696 393890 0 387558 107214 450286 187473 0 0 0 0 346786 0 341399 0 405998 338173 0 273449 0 158165 337882 0 309495 0 740250 398946 199089 258360 257061 297298 267939 305923 212845 0 960819 424950 386536 828506 0 0 316247 453213 476962 189295 0 0 0 438392 453621 0 126215 0 209610 1322125 0 1151383 0 646430 557668 0 460638 728692 362302 642197 805799 492331 330555 300387 558066 818390 305995 0 321133 286277 487950 0 299157 0 0 288877 252255 249603 0 0 0 344773 249281 0 432797 0 302665 440604 0 305412 0 290675 160762 0 0 466159 554684 328253 0 205566 138780 205015 232221 224614 -AASEGATVIAVGR MGYG000000223_01722 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,24BVM@186801|Clostridia,27MG8@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 IQ 1.0 Enoyl-(Acyl carrier protein) reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASEGELK MGYG000002293_01263;MGYG000002275_01823;MGYG000002834_00628;MGYG000003697_01698 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 0.75 976|Bacteroidetes 1.0 G 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 633988 0 660135 0 0 769310 650180 581545 428471 805239 804362 0 0 0 1140300 0 0 1777309 323336 0 0 0 625055 553749 370499 366087 815501 0 679827 0 0 302220 705797 0 0 966733 1149329 0 0 0 0 0 0 310323 402489 0 0 0 0 0 0 0 106953 0 0 0 0 0 0 0 253911 199129 201646 0 335219 0 0 0 0 243843 67147 0 0 0 0 0 0 0 915430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153143 0 0 0 0 966782 636565 0 888242 0 1284166 0 0 0 0 0 0 0 0 0 0 7249945 0 47565720 0 0 46047962 5495627 16286409 4787464 6682381 32194226 0 5589674 0 7096495 0 0 118084939 7925221 0 0 79888840 34899240 66652310 7219388 8409717 7217444 53106611 5493069 0 26070470 4788153 35057540 0 0 3799386 3026308 62265077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248232 0 0 0 0 0 153629 0 0 0 295046 0 0 0 0 0 0 -AASEGPMK MGYG000003372_00674;MGYG000002494_01669 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gapA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11395140 24043545 16849872 0 24340057 35157753 14477937 9075314 8458065 19378590 7874367 11395542 12187006 16499700 7642437 14585971 23304736 0 27042684 7659373 19266253 43530456 0 36863308 16733095 7335386 8613895 0 27106155 13583802 14236057 11919655 13004386 6946731 0 0 9251804 17174482 0 0 0 0 0 0 0 0 0 0 0 0 82464 0 0 0 0 0 0 0 0 0 0 0 0 0 152231 0 0 0 0 0 0 0 0 0 56325 95281 96025 0 0 0 0 0 799862 0 206184 0 0 0 0 0 0 0 0 0 0 160240 0 0 0 0 60862 206639 0 0 131465 0 0 0 0 243867 0 0 148406 0 0 0 0 0 0 0 0 0 307334 0 0 91658 0 0 208926 0 0 0 0 0 94824 0 0 0 122020 0 0 0 0 0 71092 0 0 156678 0 0 0 0 -AASELAR MGYG000003266_00502;MGYG000004396_01646 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG3173@1|root,COG3173@2|Bacteria,2GIZ4@201174|Actinobacteria,4CV5B@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 S 1.0 Phosphotransferase enzyme family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 APH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1162841 3075868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2524431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASELFNANSK MGYG000003891_01624 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG1653@1|root,COG1653@2|Bacteria,1TW09@1239|Firmicutes,24BZW@186801|Clostridia,36G3C@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K17318 1.0 ko02010,map02010 1.0 M00603 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.29,3.A.1.1.9 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 808409 0 0 0 0 796146 0 0 0 2593321 0 0 1213664 0 2757583 0 0 0 0 2228843 992091 0 0 0 0 957939 0 1111545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 570954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405959 0 0 0 0 563294 0 0 0 0 0 0 484038 0 0 0 0 0 0 0 170864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281743 0 0 0 0 0 0 0 0 467209 0 0 945748 0 0 0 0 0 0 437311 830829 0 0 0 0 0 0 475680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 445981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372012 0 0 0 0 304585 0 319378 0 0 -AASES(Ser->Asn)FGYNEDLIVSSDVIGMR MGYG000001255_00370 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_F|m__MGYG000001255 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1400227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASETYMYAGC(Carbamidomethyl)K MGYG000002026_00357 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__HGM13010|s__HGM13010 sp900754965|m__MGYG000002026 1.0 COG1804@1|root,COG1804@2|Bacteria,1VUFP@1239|Firmicutes,250CR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 SnoaL-like domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SnoaL_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 590598 0 0 0 0 0 0 0 0 0 0 0 893075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASEVFADR MGYG000003074_00497;MGYG000000233_00759;MGYG000002170_01548;MGYG000000205_00656;MGYG000000087_01025;MGYG000000255_01796;MGYG000002445_01460;MGYG000001617_01275 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,249GD@186801|Clostridia,21Y2S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Belongs to the UPF0271 (lamB) family 1.0 - 1.0 - 1.0 - 1.0 ko:K07160 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 LamB_YcsF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1916376 1157564 801782 1481324 1140592 1153627 1230028 1825697 1260879 1371677 963964 1192881 865540 1456720 1416214 1066516 1147130 0 1513307 1757054 1681826 1297849 0 1108594 1405554 1408378 1494781 0 1224709 1233784 0 1235412 989343 1708978 1555062 1298672 1220605 775168 3659098 3603937 3035110 3394198 3536076 2939806 3039556 3628270 2799943 3640724 2872833 3175407 3075417 2924679 2992592 3232116 3035002 0 2382896 2745463 2898462 3130636 0 3149382 2631670 2596813 3238009 0 3081924 2521338 0 3390640 3674126 3791076 3429018 3645432 3114390 2609647 1481435 1124455 1159144 999778 820389 1131385 1008655 1574210 1279284 1348767 978290 765990 1534572 1199810 1340149 1246428 1184167 0 1879160 1278220 1072675 1351111 0 1292133 1279324 1446969 1766449 0 1335675 1081111 0 1010792 867791 1722363 1315407 1013197 1195836 809343 2415382 2813018 2450484 2128492 2268407 2872593 2308096 2365812 2221730 2677688 2230537 3090802 2401200 2318385 1911150 2067345 2178564 0 2115125 2110125 2033794 2967806 0 2531151 2858038 2257399 2231046 0 2381344 1454784 0 2385818 2833413 2734685 2088422 2850040 1820970 2116879 701978 604124 609509 974949 1018410 850326 1111454 1071408 798455 788340 917662 1115567 778684 799019 692154 906635 689817 0 887090 606464 537147 1025549 0 1044104 834688 1044799 606425 0 1064857 905753 0 924376 879910 1106690 1130375 1103218 943933 874429 -AASEVNKEVK MGYG000002961_01779 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900542275|m__MGYG000002961 1.0 COG1288@1|root,COG1288@2|Bacteria,2HK5U@201174|Actinobacteria,4CUHK@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 S 1.0 C4-dicarboxylate anaerobic carrier 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DcuC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 537874 0 0 0 0 0 0 0 0 606954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASFLAADAVK MGYG000004885_00824 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotellamassilia|s__|m__MGYG000004885 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 145403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1201818 -AASFLAEGAVK MGYG000002293_00785;MGYG000002603_00166;MGYG000003697_00356 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Pentose phosphate pathway;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231168 0 0 0 0 0 0 0 0 0 329375 0 0 0 0 0 0 0 0 0 239133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409842 0 0 0 0 0 0 0 0 0 471864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1161958 0 0 854462 0 0 0 0 0 0 0 0 0 0 0 2753599 0 0 0 1149347 4796338 729558 0 0 0 1655491 0 0 0 0 734046 0 0 0 0 0 0 0 433750 0 0 967902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375372 0 860824 0 0 0 603550 0 0 0 0 0 0 0 0 0 443094 -AASFQETTK MGYG000000142_00116;MGYG000000358_00901;MGYG000000146_01134;MGYG000000231_01252;MGYG000000245_03244;MGYG000003542_00717;MGYG000000303_00569;MGYG000002996_00996;MGYG000004869_02970;MGYG000000164_01117;MGYG000000198_01126;MGYG000000271_03640;MGYG000000414_00671;MGYG000002156_00754;MGYG000001707_01472;MGYG000000193_02078;MGYG000000003_02519;MGYG000002517_00198;MGYG000004757_00585;MGYG000002057_01071;MGYG000003465_01532;MGYG000001714_01233;MGYG000002549_02931;MGYG000001683_01329;MGYG000003514_00770;MGYG000004536_01758;MGYG000002478_00805;MGYG000001338_03383;MGYG000000042_01430;MGYG000000233_00816;MGYG000001789_00145;MGYG000001666_00329;MGYG000000002_03603;MGYG000000127_00619;MGYG000000236_01798;MGYG000004763_01698;MGYG000004658_01196;MGYG000004561_01031;MGYG000001315_01195;MGYG000003493_00375;MGYG000002560_00228;MGYG000001415_02506;MGYG000000243_01979;MGYG000002926_00451;MGYG000004884_01728;MGYG000004630_01089;MGYG000000255_01999;MGYG000003684_05128;MGYG000002298_02601;MGYG000000312_01432;MGYG000000251_01868;MGYG000004885_00605;MGYG000001615_01701;MGYG000000170_00064;MGYG000000196_03983;MGYG000000179_00949;MGYG000003374_00512;MGYG000004797_04274;MGYG000001319_01768;MGYG000001617_00231;MGYG000001464_02079 domain d__Bacteria 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 0.18032786885245902 186801|Clostridia 0.5409836065573771 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 0.9836065573770492 rpoC 1.0 - 0.5737704918032787 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 0.9508196721311475 - 1.0 - 1.0 - 1.0 GH1 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism;RNA polymerase;Metabolic pathways;Pyrimidine metabolism 1.0 none 1.0 0 0 1714354 0 0 1032197 0 0 0 0 0 0 0 0 0 1912679 942711 2555099 0 1281165 0 1165904 1661035 811881 0 0 0 1565183 0 1041582 0 0 1685415 1297147 0 0 0 1477941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255335 0 0 0 0 0 0 0 0 0 0 96486 0 0 0 0 0 0 0 0 0 0 0 0 325796 503043 379078 0 475035 0 240496 322178 0 0 0 0 204989 0 401218 0 0 0 299208 0 0 0 321914 0 0 1398804 0 0 1027860 0 0 0 0 0 0 0 0 0 1128496 1471595 523207 0 1258651 0 1549338 460442 1601419 0 0 0 974191 0 1500610 0 0 1286702 526796 0 0 0 1800533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53936 0 0 0 0 0 0 0 0 -AASFQYC(Carbamidomethyl)GLR MGYG000000089_01597 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3WGK9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Glycosyltransferase family 36 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_36,Glyco_transf_36 1.0 2.4.1.49 1.0 GH94 1.0 GH94 1.0 GH94 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157738 0 0 0 0 1075914 0 0 0 0 937553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204953 0 0 0 0 0 0 0 0 0 164364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183259 0 0 0 0 185191 0 0 0 0 248725 0 0 0 0 0 0 0 0 0 0 -AASGDLSQIAK MGYG000000002_00048;MGYG000000133_00983;MGYG000000301_01136;MGYG000004733_00770 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3XZIM@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) 1.0 dapA 1.0 - 1.0 4.3.3.7 1.0 ko:K01714 1.0 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 1.0 M00016,M00525,M00526,M00527 1.0 R10147 1.0 RC03062,RC03063 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHDPS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-tetrahydrodipicolinate synthase. dihydrodipicolinate synthetase. The reaction can be divided into three consecutive steps: Schiff base formation with pyruvate, the addition of L-aspartate-semialdehyde, and finally transimination leading to cyclization with simultaneous dissociation of the product.-!-The product of the enzyme was initially thought to be (S)-2,3- dihydrodipicolinate, and the enzyme was classified accordingly as EC 4.2.1.52.-!-Later studies of the enzyme from the bacterium Escherichia coli have suggested that the actual product of the enzyme is (2S,4S)-4-hydroxy- 2,3,4,5-tetrahydrodipicolinate, and thus the enzyme has been reclassified as 4-hydroxy-tetrahydrodipicolinate synthase.-!-However, the identity of the product is still controversial, as more recently it has been suggested that it may be (S)-2,3- dihydrodipicolinate after all.-!-Formerly EC 4.2.1.52. L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5- tetrahydrodipicolinate + H(+) + H2O. 1.0 1.0 1.0 1.0 Monobactam biosynthesis;Metabolic pathways;Lysine biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 371113 406065 1192285 0 0 1516381 0 0 0 0 1066124 0 697725 0 808441 786651 0 0 0 0 1179071 1621065 0 760996 740123 351636 229936 0 1547345 0 0 485060 638022 0 0 444569 487169 777009 0 382620 265853 0 0 0 0 0 0 0 116771 0 124015 0 0 191311 0 0 0 0 121289 140404 0 240614 129342 0 113829 0 118159 0 0 0 330856 0 0 121878 0 106127 1028366 329516 544543 0 0 977886 0 0 0 0 581400 0 456899 0 1142936 734952 0 0 0 0 605456 1376713 0 767912 694959 604099 1049318 0 814999 0 0 824510 813036 0 0 701678 872459 1031804 0 0 0 0 0 0 0 0 0 0 0 0 302380 0 161087 138733 0 0 0 0 477107 351421 0 533801 0 0 0 0 1787635 0 0 0 390318 0 0 0 0 332746 2614332 2558525 2867802 0 0 1492536 0 0 0 0 2320223 0 1839887 0 3008398 2188134 0 0 0 0 3309109 2417582 0 1477713 2439899 3573544 3211538 0 4205246 0 0 3776483 3949202 0 0 2378014 1695232 0 -AASGGGYAISIK MGYG000002171_00690;MGYG000002560_02614;MGYG000002478_00950 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,2FKZT@200643|Bacteroidia,4AMS4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG NOG06228 non supervised orthologous group 1.0 susB 1.0 GO:0000272,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0004558,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:0090599,GO:1901575 1.0 3.2.1.20,3.2.1.3 1.0 ko:K01187,ko:K21574 1.0 ko00052,ko00500,ko01100,map00052,map00500,map01100 1.0 - 1.0 R00028,R00801,R00802,R01790,R01791,R06087,R06088 1.0 RC00028,RC00049,RC00077 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH31,GH97 1.0 - 1.0 GH97_C,GH97_N,Glyco_hydro_97 1.0 3.2.1.3|3.2.1.20 1.0 GH97 1.0 GH97 1.0 GH97 1.0 alpha-glucosidase. | glucan 1,4-alpha-glucosidase. maltase-glucoamylase. | lysosomal alpha-glucosidase. Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.-!-The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links. | Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides.-!-This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides.-!-EC 3.2.1.20 from mammalian intestine can catalyze similar reactions. Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. | Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose. 1.0 1.0 1.0 1.0 Galactose metabolism;Metabolic pathways;Starch and sucrose metabolism 1.0 none 1.0 0 0 1091429 0 2053080 0 1629045 0 0 0 0 0 0 1279800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1326596 0 0 0 0 1247714 0 0 0 0 556939 0 0 0 0 0 0 0 0 418767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 393162 0 0 0 0 0 0 0 0 0 938090 0 499625 0 0 0 0 0 0 526443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 171743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386199 0 488055 0 527887 0 0 0 0 0 0 347118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371594 -AASGN(Deamidated)IIPSSTGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASGNIIPS(Formyl[S](Ser->Asp)STGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASGNIIPSS(Formyl[S](Ser->Asp)TGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASGNIIPSST(Formyl[T](Thr->Glu)GAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASGNIIPSSTGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 0.9811320754716981 none 1.0 62639635 66764785 93392708 74990391 75775296 53883645 81834848 57887472 63298580 58009355 85864117 65292478 84779177 56537727 42757444 93284179 62085524 30234292 55898241 61392982 67073774 55082350 46290285 82671794 46761551 60936186 82574198 49917918 64126249 72976788 105684034 85268344 117651407 49417734 63440663 69461220 70768584 102618709 48682019 44456163 57664745 56527569 78773218 55152139 49344707 60582219 58155967 64449745 101478479 63166482 110953738 65104304 56405787 84802957 59467430 82044923 48625157 44992746 54836940 53499194 125303313 49582208 53971303 56928903 56133489 93549803 53699577 50580602 42004570 61109285 61296916 49973836 62157841 62430595 62323181 63616804 53535082 46840794 68024880 46205652 95142987 69954403 63161754 46479478 58386318 44416369 89041083 59152229 77694125 50344442 41254320 65897975 55203294 114600150 49390783 40909142 46806315 47709491 80359304 58645032 42559972 44480477 46056590 73496587 54378402 54405485 67708205 51564792 46701061 45121673 51781021 62267427 46337197 53784867 14942155 6300214 8211166 8376283 9341712 7446491 13215517 15501385 9562180 7194986 13535534 18992579 15137270 11220631 14458049 8438871 6761419 3323804 7981689 7272638 13237958 4497314 5994631 1962029 18216237 20943948 12325289 0 5413803 9877826 3590805 12804584 7978871 21724381 20795200 19155783 17634990 3846956 47562118 33261272 38909282 57427631 83846639 62711394 57210682 59622467 60238626 37953259 89639695 52032722 94648011 34380314 43794370 81440221 46605125 145728521 46241555 56681902 39166596 51271606 116696708 52697286 50152152 79336836 44778600 108167544 56659040 68122435 43897588 51442313 32588331 63868822 48425543 48366984 54908547 46609286 -AASGNIIPSSTGAAKAVGK MGYG000004536_01441;MGYG000000196_00479;MGYG000000243_01331;MGYG000001562_00044;MGYG000000044_01948;MGYG000004756_01346;MGYG000002478_03999;MGYG000000170_00182;MGYG000001415_02219;MGYG000004748_00450 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,22V16@171550|Rikenellaceae 0.5 976|Bacteroidetes 1.0 G 0.5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASGNIIPSTTGAAK MGYG000002556_00846;MGYG000003363_01174 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 C 0.5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 956339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1006495 0 0 2860086 0 0 0 0 2538943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASGQVAVLK MGYG000002517_01061 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate 1.0 dapB 1.0 - 1.0 1.17.1.8 1.0 ko:K00215 1.0 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 1.0 M00016,M00525,M00526,M00527 1.0 R04198,R04199 1.0 RC00478 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS17035 1.0 ACT,ACT_7,DapB_C,DapB_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 4-hydroxy-tetrahydrodipicolinate reductase. dihydrodipicolinate reductase. The substrate of the enzyme was initially thought to be (S)-2,3- dihydrodipicolinate, and the enzyme was classified accordingly as EC 1.3.1.26.-!-Later studies of the enzyme from the bacterium Escherichia coli have suggested that the actual substrate of the enzyme is (2S,4S)-4- hydroxy-2,3,4,5-tetrahydrodipicolinate, and that its activity includes a dehydration step, and thus the enzyme has been reclassified as 4-hydroxy-tetrahydrodipicolinate reductase.-!-However, the identity of the substrate is still controversial, as more recently it has been suggested that it may be (S)-2,3- dihydrodipicolinate after all.-!-Formerly EC 1.3.1.26. (1) (S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4- hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH. (2) (S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4- hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Monobactam biosynthesis;Metabolic pathways;Lysine biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;Biosynthesis of amino acids 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 2946746 1610574 0 0 0 0 0 0 0 0 0 0 0 562076 0 0 0 0 0 0 0 0 1868622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141952 1159773 0 0 0 0 0 260951 0 0 0 0 0 922517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1224653 1653600 0 1770165 0 0 0 1449601 0 0 0 0 0 1379069 0 0 0 0 0 0 0 0 3723304 0 0 -AASGQYETTLMSEMEK MGYG000001300_01498;MGYG000002274_02019 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 773889 0 0 0 0 0 0 0 0 0 1476497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASGVILITTK MGYG000002438_02062 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22WRD@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 787609 0 0 0 0 0 0 0 0 -AASHFVELYLK MGYG000002834_01040;MGYG000003697_02150;MGYG000002603_01099;MGYG000002293_02393 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0246@1|root,COG0246@2|Bacteria,4NEMT@976|Bacteroidetes,2FP8Z@200643|Bacteroidia,4ATAV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Mannitol dehydrogenase Rossmann domain 1.0 uxuB 1.0 - 1.0 1.1.1.17,1.1.1.58,1.1.1.67 1.0 ko:K00009,ko:K00041,ko:K00045 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00631 1.0 R00868,R02555,R02703 1.0 RC00085 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Mannitol_dh,Mannitol_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 mannitol-1-phosphate 5-dehydrogenase. | tagaturonate reductase. | mannitol 2-dehydrogenase. Tagaturonate dehydrogenase. | mannitol dehydrogenase. - D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + H(+) + NADH. | D-altronate + NAD(+) = H(+) + keto-D-tagaturonate + NADH. | D-mannitol + NAD(+) = D-fructose + H(+) + NADH. 1.0 1.0 1.0 1.0 Metabolic pathways;Pentose and glucuronate interconversions;Fructose and mannose metabolism 1.0 none 1.0 0 0 132152 0 0 267354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113326 0 0 0 0 0 0 0 0 0 0 364020 0 0 0 0 56591 0 0 0 0 0 286795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47551 0 0 0 0 0 0 0 0 0 0 91375 0 0 0 0 0 0 0 1417226 0 0 12348842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16081484 0 12497775 0 0 0 0 0 0 0 0 1745585 0 0 0 0 1687414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASHQVEASLMDLK MGYG000003693_00561 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,2FND5@200643|Bacteroidia,4AKYA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 MU 1.0 Efflux transporter, outer membrane factor lipoprotein, NodT family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OEP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 758468 0 0 0 0 889530 0 0 0 0 617202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216824 0 0 0 0 0 0 0 0 0 0 -AASINM(Oxidation)PYVNER MGYG000002603_00738;MGYG000003697_01279;MGYG000002960_02181;MGYG000002293_01728 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789169 0 0 0 0 1175067 0 0 0 0 0 0 0 0 0 0 1136827 0 1334136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASINMPYVNER MGYG000002603_00738;MGYG000003697_01279;MGYG000002960_02181;MGYG000002293_01728 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8074178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASITTSR MGYG000000022_02871;MGYG000002274_00380;MGYG000003166_01072 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3WGC8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.7.1.4 1.0 ko:K00847 1.0 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 1.0 - 1.0 R00760,R00867,R03920 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fructokinase. D-fructokinase. - ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Metabolic pathways;Fructose and mannose metabolism;Starch and sucrose metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1056552 0 0 0 0 1221360 0 0 0 0 1228460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 985489 0 0 0 0 1317089 0 0 0 0 1572144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286369 0 0 0 0 822475 0 0 0 0 1716837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 859878 0 0 0 0 262855 0 0 0 0 644244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1231395 0 0 0 0 1527175 0 0 0 0 1303938 0 0 0 0 0 0 0 0 0 0 -AASLGNDAGIYGAVR MGYG000002545_01664;MGYG000002040_01652 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHF9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 GK 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism;Carbon metabolism;Metabolic pathways;Starch and sucrose metabolism;Glycolysis / Gluconeogenesis;Streptomycin biosynthesis;Galactose metabolism;Neomycin, kanamycin and gentamicin biosynthesis;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 538307 0 0 0 0 615769 0 0 0 0 507644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 753081 0 0 0 0 716983 0 0 0 0 614474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 561339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASLNPNSDEAK MGYG000002556_01677 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-279|s__CAG-279 sp000437795|m__MGYG000002556 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22WME@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2327818 0 0 0 0 1918990 0 0 0 0 1791977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324503 0 0 0 0 0 0 0 0 0 117743 0 0 0 0 0 0 0 0 0 0 -AASLNPTMIQNIAN(Deamidated)GR MGYG000002080_00437;MGYG000003697_01278;MGYG000002960_02182 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 917777 634963 1194776 0 0 1077537 488452 768790 0 0 1231730 738597 715006 0 694838 0 0 0 0 0 0 1323287 0 642874 655793 830159 842060 0 0 0 0 951315 1176833 1050337 761297 960062 897705 853044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASLTGAGATFPAPVYAK MGYG000002504_04275;MGYG000002494_02400;MGYG000002477_00650 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,1RN5Q@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 P 1.0 Part of the ABC transporter complex PstSACB involved in phosphate import 1.0 pstS 1.0 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 1.0 - 1.0 ko:K02040 1.0 ko02010,ko02020,ko05152,map02010,map02020,map05152 1.0 M00222 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.7 1.0 - 1.0 iECH74115_1262.ECH74115_5157,iECSP_1301.ECSP_4770,iECs_1301.ECs4664,iG2583_1286.G2583_4518,iJN746.PP_2656,iZ_1308.Z5219 1.0 PBP_like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Tuberculosis;ABC transporters;Two-component system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 911500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1021607 0 834848 0 0 0 0 905259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASMADSKADEGTNNSLSPTFIIK MGYG000002293_01225 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1018454 0 0 0 0 0 0 663893 0 0 0 0 2140398 0 0 0 0 1631702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 346702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 752645 0 0 0 0 0 0 1530256 0 0 0 0 2218496 0 0 0 0 687813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 715653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASMADSKAEDDANNSLSPAFLIK MGYG000003697_01656 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 277846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1478766 0 0 794513 0 0 0 0 931973 0 0 0 0 0 0 1351890 0 0 0 972423 2262214 692444 0 0 0 1012629 0 0 0 0 956878 0 0 0 0 847074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASMDEINNFAK MGYG000000217_02630 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Acetatifactor|s__Acetatifactor sp900066565|m__MGYG000000217 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,27J20@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 GH49 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1856038 0 0 0 0 2210365 0 0 0 0 2004500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797963 0 0 0 0 931304 0 0 0 0 939294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427301 0 0 0 0 418473 0 0 0 0 480746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573157 0 0 0 0 362355 0 0 0 0 0 0 0 0 0 0 -AASMLLK MGYG000001346_03304 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,4ANQH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 531081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1337250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1077747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1527903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1614368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASMSPYFSMPNMR MGYG000002517_01769 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Phosphotransfer between the C1 and C5 carbon atoms of pentose 1.0 deoB 1.0 - 1.0 5.4.2.7 1.0 ko:K01839 1.0 ko00030,ko00230,map00030,map00230 1.0 - 1.0 R01057,R02749 1.0 RC00408 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DeoC,Metalloenzyme 1.0 - 1.0 - 1.0 - 1.0 - 1.0 phosphopentomutase. phosphodeoxyribomutase. Also converts 2-deoxy-alpha-D-ribose 1-phosphate into 2-deoxy-D- ribose 5-phosphate.-!-alpha-D-ribose 1,5-bisphosphate, 2-deoxy-alpha-D-ribose 1,5- bisphosphate, or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.6. alpha-D-ribose 1-phosphate = D-ribose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway;Purine metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 857137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 961993 1521507 0 0 0 0 0 0 0 0 1139983 1942916 0 -AASN(Deamidated)C(Carbamidomethyl)ELAFDNVIVPEENR MGYG000004642_01567 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASN(Deamidated)ESFGYNEDEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASN(Deamidated)ESFGYNEDQIVSSDIVGMR MGYG000001315_01699 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASN(Deamidated)ESFGYNTDQIVSSDIVGMR MGYG000000249_01352 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1544788 0 0 0 0 276805 -AASN(Deamidated)GELVAK MGYG000002926_00667;MGYG000002156_01167;MGYG000001824_00563;MGYG000002143_01899;MGYG000002720_00858;MGYG000002794_00766;MGYG000004487_00300 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG3246@1|root,COG3246@2|Bacteria,4NGNQ@976|Bacteroidetes,2FQZR@200643|Bacteroidia,22WVP@171551|Porphyromonadaceae 0.8571428571428571 976|Bacteroidetes 0.8571428571428571 S 1.0 3-keto-5-aminohexanoate cleavage protein 0.8571428571428571 - 0.8571428571428571 - 1.0 2.3.1.247 1.0 ko:K18013 1.0 ko00310,map00310 1.0 - 1.0 R10564 1.0 RC02728,RC03199 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 BKACE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-keto-5-aminohexanoate cleavage enzyme. - The enzyme, isolated from the bacteria Fusobacterium nucleatum and Cloacimonas acidaminovorans, is involved in the anaerobic fermentation of lysine. (5S)-5-amino-3-oxohexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA + acetoacetate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 3343932 2631887 1916684 2486009 2001583 1878043 3314032 2782494 2610654 2346354 1561806 1658364 1819578 3810972 2795729 2009528 1932932 0 2904900 2445675 2477214 2444909 0 2708882 2726663 3003420 2545506 0 2696052 0 1803701 2039325 2154210 4071419 2900630 2577920 2914557 1878996 869188 329707 194305 698310 387146 377931 567044 871778 797724 630642 308875 338221 355211 548811 755006 144007 399720 0 835566 746731 512191 205054 0 346030 531726 707546 819734 0 882852 0 374767 483479 298823 867328 1009522 809753 1005690 530617 2529049 2240160 1997934 2016906 1198553 2088728 2222337 3111165 2423744 2972842 1188590 1702822 2217238 2783227 2628831 1708238 3069332 0 3479622 2832737 2407310 2716158 0 1639235 2678026 2815347 1771652 0 2579897 0 1557475 1349766 2359609 3097759 2654923 2345622 2812550 1435769 1759133 1679402 1700095 1586996 1082993 1879760 1647116 2526597 1725645 1986072 1254033 1500526 1037230 1344859 2198615 796640 1415403 0 1314636 1177099 593614 1244598 0 1787628 0 1559912 1330762 0 3056554 0 1566503 2179501 2289603 2361322 1776982 1384446 1974452 1132904 0 0 254558 186548 295294 1317104 716886 0 0 629291 45027 0 318590 0 890108 629765 0 0 0 0 635396 736546 0 932125 858186 0 199572 0 0 0 0 0 642550 139986 1488591 1876174 0 0 -AASN(Deamidated)GELVEK MGYG000000099_02236 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG3246@1|root,COG3246@2|Bacteria,1TQNV@1239|Firmicutes,248TX@186801|Clostridia,268HP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 S 1.0 beta-keto acid cleavage enzyme 1.0 kce 1.0 - 1.0 2.3.1.247 1.0 ko:K18013 1.0 ko00310,map00310 1.0 - 1.0 R10564 1.0 RC02728,RC03199 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 BKACE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-keto-5-aminohexanoate cleavage enzyme. - The enzyme, isolated from the bacteria Fusobacterium nucleatum and Cloacimonas acidaminovorans, is involved in the anaerobic fermentation of lysine. (5S)-5-amino-3-oxohexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA + acetoacetate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 0 0 0 295496 0 0 383999 222014 0 420020 0 0 0 0 0 0 0 0 0 0 0 0 0 109536 216460 269914 0 0 0 0 0 0 376330 208854 0 0 0 0 1988205 0 1875860 1667723 0 1707305 1631202 2703989 2038055 2342912 0 1531193 0 0 0 1142468 0 0 0 1654214 0 1255715 0 1371811 1355455 2180789 2071643 0 0 0 0 0 1851869 2123271 2278579 1966566 2038799 1688986 466177 0 0 212760 0 0 0 0 0 0 0 0 0 0 0 213956 0 0 0 160823 0 312295 0 0 288647 0 0 0 0 0 0 0 0 0 0 587329 0 673657 332944 0 0 0 0 374830 365406 0 274975 0 0 539506 0 0 0 218091 0 0 0 471456 0 0 0 0 600346 395559 294010 0 0 0 0 0 551747 0 874604 0 415615 625773 0 0 0 247913 0 202858 99505 292221 0 212654 0 0 0 0 0 148088 0 0 0 142661 0 91155 0 241783 0 218580 0 0 0 0 0 0 336131 231466 90317 0 0 0 -AASN(Methyl[N](Asn->Gln)ESFGYNTDEIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNC(Carbamidomethyl)ELAFDNVIVPEENR MGYG000004642_01567 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 693672 0 729616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNC(Carbamidomethyl)EVIYENVK MGYG000000177_01043 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 1093710 0 446631 982294 0 787098 0 0 839734 0 0 0 0 0 0 0 0 0 765689 0 815427 851273 0 583526 0 855300 1043942 0 975341 666475 0 0 730909 0 821457 0 0 375863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 759464 0 646900 494975 0 0 0 0 438452 0 0 0 0 0 767456 0 0 0 776229 0 359325 419794 0 377199 0 673137 771366 0 706976 644114 0 0 640870 0 844122 0 838496 557507 146408 0 661180 0 0 327353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 344375 0 503215 0 0 0 0 0 0 0 0 623410 0 0 0 0 574623 473047 0 495840 436453 0 0 0 0 303896 0 0 0 0 0 614629 0 0 0 330987 0 0 0 0 0 0 270178 569784 0 494593 0 0 0 357834 0 455479 0 305116 0 -AASNC(Carbamidomethyl)EVIYENVKVPAENLLGK MGYG000000177_01043 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 2263247 1827348 2214898 3352209 0 1495304 0 0 1815073 0 0 0 0 0 2373339 0 0 557735 2246823 2034212 2316626 2307910 645983 1458731 2820942 1946844 2172653 739187 2556440 2140570 0 0 1790743 0 2270187 0 2227432 1640789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550173 0 0 0 0 752793 0 0 0 0 660550 0 0 0 0 0 0 0 0 0 555263 1979814 1600731 1623515 1309874 0 847141 0 0 1369118 0 0 0 0 0 2397641 0 0 529959 2083630 2435318 952103 1569569 558641 902086 1675353 2326238 2185034 305442 2134350 1428688 0 0 0 0 2184180 0 1588266 1518895 567033 224940 700252 327188 0 242610 0 0 260371 0 0 0 0 0 478039 0 0 130520 402120 338784 371984 464883 0 454865 477889 349726 224082 0 173792 218398 0 0 1092218 0 462914 0 430109 552060 442070 582268 343382 291523 0 503972 0 0 264479 0 0 0 0 0 353109 0 0 0 543046 344854 418640 689366 0 817247 582335 696601 608877 0 461732 381897 0 0 130009 0 263935 0 1462366 507527 -AASNC(Carbamidomethyl)EVIYENVKVPAENLLGKEGQGYK MGYG000000177_01043 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNC(Carbamidomethyl)EVIYENVR(Arg->Ala)VPKENLLGK MGYG000002791_01146;MGYG000000016_02518 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 1738437 0 0 0 0 2747286 0 0 0 0 0 0 2169551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2220826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1862141 0 0 0 1409351 0 0 984093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2295524 0 0 0 0 0 0 0 0 0 549102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNC(Carbamidomethyl)EVIYENVR(Arg->Lys) MGYG000002791_01146 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__|m__MGYG000002791 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 725734 960401 0 0 0 0 0 0 1195204 629614 0 0 0 903942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1007698 983111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNE(Cation_Ca[II])SFGYNEDEIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 605608 0 0 0 0 0 471967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1190333 1082504 0 0 0 0 0 -AASNE(Cation_Ca[II])SFGYNEDEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 377950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNE(Cation_Fe[II])SFGYNEDEIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1578028 0 0 1038678 0 0 0 0 0 797216 -AASNE(Cation_Fe[II])SFGYNEDEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 867460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 985418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNE(Glu->Asn)SFGYNEDQIVSSDIVGMR MGYG000001315_01699 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 3101860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1378068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4964734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2965841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNE(Glu->Gln)SFGYNTDEIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNES(Deoxy[S](Ser->Ala)YGYNTDEIVSSDIVGMR MGYG000004740_01468 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eubacterium_I|s__Eubacterium_I sp900557275|m__MGYG000004740 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNES(Ser->Asn)FGYNTDEIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1868001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYN(Asn->Thr)TDEIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740239 0 2994118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3133873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYN(Deamidated)EDEIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1111941 0 0 0 0 0 0 0 0 -AASNESFGYNDEQIVSSDI(Xle->Val)IGMR MGYG000000215_01375 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella stercorea|m__MGYG000000215 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYNDEQIVSSDII(Xle->Val)GMR MGYG000000215_01375 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella stercorea|m__MGYG000000215 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1992645 0 0 0 0 0 0 783538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYNE(Cation_Ca[II])DEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 572151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYNE(Cation_Fe[II])DEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 180421 0 0 454671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 666680 0 0 94315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYNE(Cation_Na)DEIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 315801 0 356868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309621 0 0 0 0 0 0 166303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159381 0 0 0 0 0 292287 0 0 0 0 0 0 0 0 2489485 0 3453956 0 0 0 1517826 1441479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1908743 0 2304631 0 4319141 0 1923287 0 0 0 0 1861868 0 0 -AASNESFGYNE(Cation_Na)DEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 941666 891337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1265618 1030485 0 0 0 0 0 0 0 0 0 0 0 652741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3062377 1491923 351197 0 778960 0 0 0 0 2115160 0 0 0 0 0 0 0 0 0 0 0 0 0 919260 0 0 0 0 0 0 0 0 0 0 0 0 640557 0 0 0 0 0 0 0 0 0 0 0 1327497 0 0 0 0 0 0 0 842686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1942808 0 2599191 0 955473 0 0 0 0 1428293 0 3028204 0 0 0 0 0 0 0 0 0 0 0 352094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1336207 0 0 651166 0 0 0 0 -AASNESFGYNE(Cation_Na)DQIVSSDIVGMR MGYG000001315_01699 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYNE(Glu->Gln)DEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1301321 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYNED(Asp->Asn)EIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 2823666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1395539 0 0 1737976 1336698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409964 0 0 0 0 0 0 606428 0 0 0 0 0 0 0 0 0 0 423725 0 0 0 0 0 0 0 0 0 0 987983 0 0 0 0 0 0 0 0 788982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1508985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYNED(Cation_Ca[II])EIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 250120 289580 0 99916 0 0 0 0 0 176997 142006 0 0 0 0 129912 153171 0 0 0 0 0 0 0 0 64264 0 0 0 0 0 0 0 0 0 0 206305 0 235104 237592 0 211349 0 0 154958 0 0 0 213198 0 0 0 0 173313 91200 0 0 0 0 0 0 0 0 257600 0 0 0 0 0 0 0 0 0 0 262841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207813 392258 0 276696 0 0 92899 0 0 162791 230540 0 0 0 0 232274 346027 0 0 0 0 0 0 0 0 632381 0 0 0 0 0 0 0 0 0 0 178574 0 1013619 947213 0 1439687 0 0 946582 0 0 1158204 749416 0 0 0 0 798062 836648 0 0 0 0 0 0 0 0 714180 0 0 1599452 0 0 0 0 0 0 0 108400 0 -AASNESFGYNED(Cation_Ca[II])EIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 720726 659218 0 0 785011 0 0 0 492292 928928 517459 482411 0 301367 398129 0 0 0 0 0 590190 0 291494 0 0 0 0 625394 689109 474087 655068 355069 0 0 0 0 602892 0 917152 191124 0 0 70189 0 0 0 123349 338410 76363 209528 0 76773 70102 0 0 0 0 0 156942 0 196876 0 0 0 0 626684 333689 949740 466902 88290 0 0 0 0 157479 0 0 441029 0 0 140983 0 0 0 376979 221221 608180 312581 0 383992 333073 0 0 0 0 0 1042588 0 169301 0 0 0 0 416461 330181 386763 1306513 534923 0 0 0 0 401457 0 1082557 428350 0 0 298033 0 0 0 318820 457661 184650 543508 0 128590 392817 0 0 0 0 0 441198 0 312182 0 0 0 0 828697 404231 1006713 673933 382906 0 0 0 0 529868 0 0 556434 0 0 201375 0 0 0 107789 238396 158728 160071 0 129239 261488 0 0 0 0 0 102021 0 83387 0 0 0 0 173142 0 492587 0 511179 0 0 0 0 379814 -AASNESFGYNED(Cation_Fe[II])EIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 956989 0 0 0 0 0 0 0 0 0 0 0 0 0 617435 0 0 0 0 1102060 0 0 0 0 0 0 0 0 0 0 0 0 943809 0 0 0 0 -AASNESFGYNED(Cation_Fe[II])EIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 682615 673910 0 0 672581 0 648023 0 0 925480 0 0 0 0 0 0 0 0 0 361129 511923 0 263716 0 0 0 0 698559 0 412263 0 409597 0 0 0 0 569695 0 795079 88899 0 281268 134330 0 145754 0 0 192814 0 0 0 0 0 0 0 0 0 131814 0 0 247999 0 0 0 0 368249 0 0 387701 91704 0 0 0 0 117281 0 307940 89178 0 97763 202980 0 325386 0 0 263644 0 0 0 0 0 0 0 0 0 139048 401195 0 207482 0 0 0 0 250949 0 353067 908793 498679 0 0 0 0 277842 0 0 272934 0 464806 159596 0 112896 0 0 191764 0 0 0 0 0 0 0 0 0 257740 77627 0 264047 0 0 0 0 664204 0 950802 543319 139104 0 0 0 0 283763 0 0 378104 0 189395 52519 0 176608 0 0 78706 0 0 0 0 0 0 0 0 0 47476 156704 0 0 0 0 0 0 111311 0 302371 644227 248480 0 0 0 0 95595 -AASNESFGYNED(Cation_Mg[II])EIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYNED(Cation_Na)EIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564841 0 0 0 0 0 0 0 0 0 0 0 0 2590738 0 2116931 0 0 1163280 0 0 0 0 0 0 0 0 2672997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2795063 0 0 0 0 -AASNESFGYNED(Cation_Na)EIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1013275 2103945 2029953 0 1574009 1870141 0 1403476 0 1321870 2688175 1600710 1299919 0 0 1113685 1233222 1174098 919712 828315 1056839 1669700 921165 792900 1010712 0 927946 1941294 2021903 1888199 1490259 2086535 0 0 1027353 721729 1107494 1717795 528028 2443362 403230 0 1130278 436058 0 0 0 303795 940749 377166 818362 283173 469451 313524 310488 1610846 409007 579045 470636 288448 687902 886273 549704 700906 827039 1243710 1247179 818757 0 0 312941 848039 0 594029 552853 506958 784907 0 712636 0 430035 807524 0 931093 0 772546 740843 1072073 780066 736091 829051 0 1177763 399440 752733 728937 752153 1429255 531865 715532 772142 858008 865691 846509 0 809227 1146931 2441412 1527887 932349 1144653 700353 667437 983267 359535 3461535 0 0 1613113 632523 0 397244 0 0 0 613682 1196427 375327 323974 740747 824377 431003 390527 504703 818317 879831 0 795336 349659 387723 520819 540103 0 435253 0 2021809 0 152617 281121 306347 268997 0 335136 0 1167616 0 505557 403849 0 198231 0 259654 743775 400045 595311 424646 319622 638413 301129 224638 344527 184916 232283 380414 501726 218740 240235 137441 212143 656014 342869 237461 0 1957853 0 130419 0 166681 72439 848750 -AASNESFGYNED(Cation_Na)QIVSSDIVGMR MGYG000001315_01699 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 456130 698208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436040 0 0 0 0 0 368138 0 0 0 0 0 0 0 566512 0 0 313942 0 641161 797079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1169221 0 0 0 0 0 633317 0 0 0 0 0 0 0 809206 0 0 354302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316119 0 0 0 0 0 0 0 0 0 0 0 0 0 421276 0 0 0 0 361746 478646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406503 0 0 0 0 0 255262 0 0 0 0 0 0 0 106794 0 0 0 0 229206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219875 0 0 0 0 0 0 0 314828 0 0 0 0 -AASNESFGYNEDE(Cation_Na)IVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726514 0 0 0 0 0 0 0 0 0 0 226661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 989318 0 0 0 0 0 0 0 0 0 0 0 0 285075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1785707 0 0 0 0 0 -AASNESFGYNEDE(Glu->Gln)IVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1804009 0 0 0 0 0 0 3543488 0 0 0 0 0 1296476 1565600 0 1376302 0 0 0 1508507 0 0 0 0 0 0 0 0 0 0 0 0 0 2270541 1211655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 881826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421062 0 0 570110 0 0 0 0 0 0 0 565788 0 0 0 0 0 0 0 0 0 0 589645 515504 0 1026733 0 0 0 0 0 0 0 0 0 0 0 0 961865 0 0 975834 0 1591285 2160632 0 0 0 0 954972 0 0 0 0 0 0 0 0 0 0 0 426938 0 449793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYNEDEIVSSDIVGM(Oxidation)K MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 224960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1147060 1292254 1169403 1930402 0 796120 1723908 829366 663618 1473903 2188085 917833 1481455 3129280 1157175 914606 923774 0 1137123 0 1921543 1190030 0 963411 1665125 939683 1894674 0 1967618 0 848719 1407724 2430709 1399018 1322597 1495349 1184681 1050322 -AASNESFGYNEDEIVSSDIVGM(Oxidation)R MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 575879 1088398 1243576 0 1195127 1161066 0 0 441591 387468 1453016 933396 0 439318 521630 1594801 1637884 2462752 388710 396064 0 2025014 643261 689038 656954 403862 0 565001 953009 0 676781 1247990 711146 0 0 0 242581 800201 266875 1102429 208849 0 509263 323255 0 0 623390 324083 432543 0 0 0 193499 206793 0 851867 110302 317676 0 0 392355 259138 0 179801 0 500900 622600 0 2078062 948021 0 0 0 0 229315 167814 397101 3937466 621312 0 221998 675834 0 0 427373 599279 276421 761868 0 550058 597886 573924 786023 0 366157 682165 0 1098462 334205 598057 632229 902665 0 404454 443794 0 547527 2126818 1100261 0 0 0 437175 681149 0 1637901 624500 0 1061444 365601 0 0 337374 359521 866189 397406 0 381368 186577 491673 611613 244067 149811 313068 0 552916 406167 682646 313760 328873 0 886283 1211711 0 1430245 1223391 760810 0 0 0 169488 879676 192425 2011558 555285 0 354955 214935 0 0 0 153734 551349 203442 0 373797 332986 388989 0 278781 0 0 0 357221 481383 220078 214334 0 0 605773 369959 0 711556 1373315 1157461 0 0 0 160080 508244 -AASNESFGYNEDEIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10739095 9739351 9364914 16092352 973700 4856424 12612512 6334462 6148312 13587749 16727620 6380161 12755604 21220087 11957852 7523754 8288357 0 11215803 2336886 12791762 7826040 0 8215239 11973532 10623175 13796803 0 17337419 2125309 8670568 14234659 21056479 12671001 10404668 16299917 9227332 8513088 -AASNESFGYNEDEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 3649604 8108166 9097159 2189600 7313039 9961200 1613892 5552081 3858987 4901433 11739331 5620271 5139967 3258686 3405323 4287847 5802453 6157200 3880905 3342438 3858565 6020263 4547901 3371932 3593972 2813446 3527767 6889237 7283613 7343083 5896832 9081930 4607723 3272677 3317447 2688156 2721017 5867586 1975547 9802594 1162758 2189055 4549277 1804334 3212294 2314556 1411727 1084792 3783625 1324602 2194348 1186473 1482175 1177390 1513646 7175514 1330537 2442705 2252367 1104769 2636528 3431505 1480430 2355566 2739802 4742368 5422246 3021389 15231390 6907737 1747058 2523186 2488224 2332295 1706148 1649229 2219974 10880589 2967242 2112130 1656678 2880310 1791390 3058135 1616943 2918965 2340007 3709464 3072624 2276946 2867024 3451611 3800083 780539 2845993 2335628 3048293 5311276 1607759 2070377 2924967 3632830 2993036 2225487 2277999 2787244 4563698 8056485 4998597 3764309 3838936 2088876 2350191 3201465 1556510 13259763 5114874 1699788 6326962 2471133 1859110 1811477 1756149 2321245 3259443 2089223 4113198 1588200 1440012 3340602 2626883 1472219 1329118 2290623 2731078 2943185 888375 2796364 1545418 1481087 2075238 2864227 7815965 3234479 10476089 6903015 3913127 663182 2023876 1483301 1265727 6112894 1260098 9362730 3912185 959040 1574100 1126472 1385550 1246029 706217 1087901 4203598 1197075 2837495 1843723 1015233 2222073 868792 880951 833166 478486 917913 1216977 1822553 1431521 1317689 927403 2074862 2557361 1217690 857410 4325405 5765613 10472181 2429429 14367651 2601912 1131615 3870965 -AASNESFGYNEDQIVSSDIVGM(Oxidation)R MGYG000001315_01699 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 531646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308554 0 0 0 0 642788 0 0 226524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236826 0 0 0 0 282846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268584 0 0 0 0 0 0 0 869959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724503 0 0 0 0 939041 0 0 446548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492199 0 0 0 0 430802 -AASNESFGYNEDQIVSSDIVGMR MGYG000001315_01699 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 518386 2190326 3414297 1216718 0 0 788928 0 0 2002320 3685180 0 0 0 0 0 879302 0 2097031 0 0 0 0 0 0 0 0 0 860036 0 0 1638001 1929883 0 0 0 1383037 2733164 1955066 2556329 2385270 2887698 1809188 1927844 2866261 3052826 1374335 1758328 1161636 1330819 2753812 1628661 2132286 1228148 0 0 2299674 4624926 1924887 1018704 0 2931840 2673948 2118955 2144203 0 2571424 1539090 3133014 3485149 1686351 1879408 2124858 2126226 1599215 2400074 392165 725113 482778 537506 451131 582061 575379 614629 519685 650260 612872 1026681 560421 691496 654431 1082248 712171 0 576786 703934 791239 539991 0 278826 665257 983975 666751 0 756020 709257 527635 736667 1349192 596578 775544 722012 319661 685343 0 1574436 3074226 1117776 1378095 1318191 0 0 732318 1088145 0 2611798 1897513 1195350 831965 2558208 1515605 0 0 0 1214249 0 0 0 0 975653 1523199 0 0 1098118 1993300 1477520 3473213 572026 0 0 721728 3078554 1012560 680913 2619382 1015841 635699 534880 1167909 1072347 714183 953972 1078561 730056 1680033 1611004 1225557 1334876 1091089 0 1374423 675417 0 719016 0 426262 1348175 796008 1263534 0 1445332 441462 1134437 925814 3350849 1098762 1672292 1192332 1183186 3049237 -AASNESFGYNTD(Cation_Na)EIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 521778 0 0 0 0 0 0 0 402088 0 0 0 0 0 0 0 318484 697237 0 0 0 0 624283 0 0 234876 0 942163 0 0 0 0 0 456739 609540 246804 379061 0 516052 0 0 0 0 0 0 0 656726 0 0 0 0 0 0 0 1399872 741200 0 0 0 0 452358 0 0 742388 0 669753 0 0 0 0 0 768623 842424 682668 0 0 566084 0 0 0 0 0 0 0 183285 0 0 0 0 0 0 0 319670 1535899 0 0 0 0 0 0 0 429277 0 469170 0 0 0 0 0 228417 425885 0 315434 0 297117 0 0 0 0 0 0 0 287979 0 0 0 0 0 0 0 710079 56619 0 0 0 0 0 0 0 345633 0 171308 0 0 0 0 0 335124 207039 200678 145903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1227143 0 0 0 0 -AASNESFGYNTDE(Cation_Na)IVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 627471 0 0 0 0 0 0 0 0 0 591642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYNTDEIVSSDIVGM(Oxidation)R MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 251481 0 0 313039 0 527628 349853 0 0 0 0 0 0 0 364755 1141497 0 0 0 370336 720970 233067 0 0 0 761519 0 0 0 0 195378 243717 0 0 0 166156 0 0 253005 0 0 389220 0 411127 715294 0 0 0 0 0 0 0 685959 584631 0 0 0 293723 249490 316957 0 0 0 365573 0 0 0 0 287205 407937 0 0 0 676728 0 0 197144 0 0 209317 0 461506 344574 0 0 0 0 0 0 0 508608 357970 0 0 0 224061 583446 263164 0 0 0 344390 0 0 0 0 261915 337693 0 0 0 0 0 0 399884 0 0 317974 0 404483 308651 0 0 0 0 0 0 0 635170 216887 0 0 0 273620 0 374178 0 0 0 423420 0 0 0 0 430959 492749 0 0 0 416959 0 0 525745 0 0 688527 0 268658 0 0 0 0 0 0 0 0 0 0 0 0 0 547437 347746 796161 0 0 0 204661 0 0 0 0 798557 309669 0 0 0 522209 -AASNESFGYNTDEIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 1266399 1086991 1369616 1344694 1052721 1102408 1164779 2016625 1521340 1577632 1723775 1412506 1105730 1289365 1351404 890591 984016 2579654 1291258 1159000 946543 993897 2461717 935368 1446413 1140985 1085202 3251832 1472724 1773567 1260798 1115407 787684 1420811 1704113 1039660 1147805 922230 1893917 2034501 1692717 2504317 2728288 1421110 3314368 2440361 1399349 1940067 1900920 2109041 3088723 2207259 2377529 3009472 5463975 2828828 2000101 2338821 1882416 1042614 1666795 1387833 2228783 2053996 2161642 2274452 2739765 2018144 2066594 2655907 2006419 2270824 2312326 1955543 2057422 1750916 1632746 1256167 1067532 689595 898641 631439 1249103 1789358 1316175 0 931704 1229096 0 1511128 1864729 1215341 1507739 621946 1489372 1482579 1196597 954706 1498565 822104 1591938 1636223 1614809 1777789 1251674 1650504 1254616 984186 1577654 2090710 1506515 1120111 1668270 958263 995423 1134868 1258192 1201508 919126 1019980 1377280 1437869 1105766 1432551 860794 803327 1106162 889929 871966 1137338 2515006 472303 1144677 992410 2274073 1162079 3021653 7551032 1091823 966620 1138167 984551 903724 695107 995252 1179232 1755606 2111907 3613152 1970482 2258384 1538163 2711071 5394511 8012371 23060521 0 9579666 4602235 2038524 1766342 4608953 372210 824528 11861389 16018923 371070 5598551 8626821 1264839 352101 2564820 8138908 1857452 6538920 19288432 1057885 284965 2813815 0 18015063 0 413106 1130049 1438084 2976712 16522118 246058 649842 20297496 -AASNESFGYNTDQIVSSDIVGMR MGYG000000249_01352 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573790 0 0 0 0 0 0 0 0 0 392592 0 0 0 0 0 0 0 0 0 0 0 0 279093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136377 0 0 0 0 0 0 0 0 0 0 0 0 677012 0 0 0 0 0 0 0 0 0 0 0 0 750156 0 0 0 0 0 0 1065781 0 0 0 0 1003924 0 0 639083 0 896087 0 0 0 0 806330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESFGYNTEEIVSSDVIGMR MGYG000003582_01256 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__CAG-272|g__Firm-07|s__Firm-07 sp900770145|m__MGYG000003582 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNESY(Tyr->Phe)GYNTDEIVSSDIVGMR MGYG000004740_01468 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eubacterium_I|s__Eubacterium_I sp900557275|m__MGYG000004740 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASNEVIKK MGYG000000271_02066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,27IMH@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Fibronectin type III-like domain 1.0 - 1.0 - 1.0 3.2.1.21 1.0 ko:K05349 1.0 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 1.0 - 1.0 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 1.0 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH3 1.0 - 1.0 Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C 1.0 - 1.0 GH3 1.0 GH3 1.0 GH3 1.0 beta-glucosidase. gentobiase. Wide specificity for beta-D-glucosides.-!-Some examples also hydrolyze one or more of the following: beta-D- galactosides, alpha-L-arabinosides, beta-D-xylosides and beta-D- fucosides. Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose. 1.0 1.0 1.0 1.0 Phenylpropanoid biosynthesis;Metabolic pathways;Starch and sucrose metabolism;Cyanoamino acid metabolism;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 156831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1400441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394137 0 0 0 0 0 0 0 0 -AASNGELVAK MGYG000002926_00667;MGYG000002156_01167;MGYG000001824_00563;MGYG000002143_01899;MGYG000002720_00858;MGYG000002794_00766;MGYG000004487_00300 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG3246@1|root,COG3246@2|Bacteria,4NGNQ@976|Bacteroidetes,2FQZR@200643|Bacteroidia,22WVP@171551|Porphyromonadaceae 0.8571428571428571 976|Bacteroidetes 0.8571428571428571 S 1.0 3-keto-5-aminohexanoate cleavage protein 0.8571428571428571 - 0.8571428571428571 - 1.0 2.3.1.247 1.0 ko:K18013 1.0 ko00310,map00310 1.0 - 1.0 R10564 1.0 RC02728,RC03199 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 BKACE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-keto-5-aminohexanoate cleavage enzyme. - The enzyme, isolated from the bacteria Fusobacterium nucleatum and Cloacimonas acidaminovorans, is involved in the anaerobic fermentation of lysine. (5S)-5-amino-3-oxohexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA + acetoacetate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 3266745 1855448 2322448 3723424 1738652 2058161 5023882 2758521 3602271 2478046 2305859 2335478 1722883 3610123 2883249 1740721 2412130 2311382 2034724 2166718 2514829 3049399 3107991 3893437 3431908 3587908 2901104 2514061 3694874 1576980 2652582 1827162 2193271 4009707 3907564 3758426 4538230 2545696 903317 610713 626187 1299456 655895 756956 1114757 1175895 1134582 1104573 738031 471445 640815 1049773 961801 550674 941574 1940351 1379184 1285603 795007 702746 3042419 599516 919193 1016130 1146318 2557731 738613 769668 0 795030 609630 1028148 1284720 872751 1031220 659665 3146134 2118988 2855264 3369166 2705511 4014583 3828908 4653686 4587505 3763625 2695902 3359269 2692088 4786729 3555553 2909324 4312135 8763713 3698848 3557653 3272971 3590144 5988710 4188568 4535857 4473369 3621277 5246145 4093588 3902264 3803558 3022338 3633456 4213658 4223384 4970667 3166080 3209121 1538856 1345911 1528170 1109283 1161046 1139728 1320765 1428672 1186023 1688229 961883 1466480 835504 976955 2006374 622496 1001964 2045955 1497185 859866 545112 1241273 1036318 1488059 1316960 1288090 1124690 1326532 1765343 1400508 1422249 1303571 1794794 1761900 1494791 1184250 1293571 1166236 619867 257683 287151 0 0 532570 396556 368638 325788 671978 0 851080 225174 414550 261686 585711 300655 843648 244675 0 0 229102 1036523 297146 294164 549158 0 722822 322067 524720 0 264408 0 503335 546224 907910 0 0 -AASNGELVEK MGYG000000099_02236 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG3246@1|root,COG3246@2|Bacteria,1TQNV@1239|Firmicutes,248TX@186801|Clostridia,268HP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 S 1.0 beta-keto acid cleavage enzyme 1.0 kce 1.0 - 1.0 2.3.1.247 1.0 ko:K18013 1.0 ko00310,map00310 1.0 - 1.0 R10564 1.0 RC02728,RC03199 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 BKACE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 3-keto-5-aminohexanoate cleavage enzyme. - The enzyme, isolated from the bacteria Fusobacterium nucleatum and Cloacimonas acidaminovorans, is involved in the anaerobic fermentation of lysine. (5S)-5-amino-3-oxohexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA + acetoacetate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 none 1.0 0 0 516143 320640 0 0 546795 0 375930 0 0 0 0 0 517616 0 0 0 0 210520 0 0 0 0 0 306199 0 0 0 0 0 0 0 0 0 0 297577 490297 2968025 0 1214130 2464090 1373153 0 2292919 1975019 2950588 2249088 1676051 1603385 0 1786939 1738708 1011547 1639347 0 1776552 2015204 0 0 0 0 1447763 1922037 2142738 0 0 0 0 0 1401391 0 0 2466960 1980028 1052614 0 0 0 105776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141696 0 933748 810304 582297 0 638383 0 502726 550776 335320 808478 0 474953 0 733666 541041 0 466449 329068 0 0 0 0 370787 0 0 0 0 0 0 0 637425 0 0 0 0 830996 214596 0 0 0 0 0 0 315540 0 0 0 226024 0 0 0 279094 0 0 215853 222892 0 0 0 0 0 0 226805 0 0 0 0 0 0 0 0 227847 0 0 -AASNTNAYYSVSK MGYG000000089_02197 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1578044 0 0 0 0 1787279 0 0 0 0 1248211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASPAAEIMEK MGYG000000243_00038 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0702@1|root,COG0702@2|Bacteria,4NEPE@976|Bacteroidetes,2FMBU@200643|Bacteroidia,4ANN0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASPVELTTIK MGYG000002485_01479 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,378RN@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1469446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASPVELTTIKPVGK MGYG000004893_00001;MGYG000002485_01479 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,378RN@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pyruvate metabolism;Citrate cycle (TCA cycle);Carbon metabolism;Butanoate metabolism;Carbon fixation pathways in prokaryotes;Metabolic pathways;Glycolysis / Gluconeogenesis;Microbial metabolism in diverse environments 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5479851 3690785 10478133 1446195 5038003 11237081 7115549 5319452 6505238 15140779 9442592 5782792 9087455 6625182 4687468 12603980 9327403 0 4809831 4068168 4811181 14741327 0 11510724 4145286 4863242 5766914 0 3898234 6462751 8290906 3438562 11420256 5207446 6684664 5909400 5352127 9973157 128044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASQFEALR MGYG000002478_00339;MGYG000004797_04223;MGYG000001378_04186;MGYG000000236_01414 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Carbon metabolism;Glyoxylate and dicarboxylate metabolism;Valine, leucine and isoleucine degradation;Carbon fixation pathways in prokaryotes;Metabolic pathways;Microbial metabolism in diverse environments;Propanoate metabolism 1.0 none 1.0 2667029 2248554 2088400 2827831 3275735 2973820 2945973 1593511 2402842 2110032 2080518 0 2434745 2847499 1977054 3421168 3346200 671588 0 2787650 2842675 2505717 995340 3801104 1838980 2406831 3087296 1055792 3145399 2759089 3139071 3550566 2667285 968994 3130372 3203929 2681839 2472050 1917704 217372 0 1815864 1713012 223079 0 1855570 1120306 198518 0 0 1086004 1391023 1506678 0 0 450525 799828 1630765 1303065 0 473173 0 1003588 1163608 128863 482049 1398161 729075 0 1371861 0 932139 2218391 606741 1660587 0 2234062 1292045 2699742 2480828 2591443 3058178 2460446 1929445 2670954 2485389 2008750 0 1887824 2196230 2361709 2210564 1776230 1995507 2271687 2153983 1857995 1913159 1931885 2771578 1974416 1792447 2125823 556189 1946227 1876370 3254607 1560630 2119257 808573 2406300 2494952 2076576 2245904 5178645 5270823 0 0 320982 398208 4129484 983400 1024736 0 921765 0 0 873983 245031 789447 0 0 0 291635 198953 1461748 0 578652 740495 363508 818062 0 417100 0 0 6943860 0 7197034 1060854 5771189 5277170 3390448 2320848 1432177 1557975 2122557 3622505 2273496 2207344 2386929 2262826 1131199 920376 0 2318310 491336 1857884 2325040 400051 1464739 2809808 3294032 1632438 2128931 1830556 2050211 1718752 991003 1889060 1275971 2324586 3092003 1906260 1862010 959229 2641315 2213346 1666824 2283795 2081434 -AASQSIIPVDTK MGYG000002494_04272 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,3WX4Q@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate 1.0 epd 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019318,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043891,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048001,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.0 1.2.1.12,1.2.1.72 1.0 ko:K00134,ko:K03472 1.0 ko00010,ko00710,ko00750,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map00750,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00124,M00165,M00166,M00308,M00552 1.0 R01061,R01825 1.0 RC00149,RC00242 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iYL1228.KPN_03356 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). | erythrose-4-phosphate dehydrogenase. triosephosphate dehydrogenase. | erythrose 4-phosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. | Was originally thought to be an EC 1.2.1.12, but this has since been disproved, as glyceraldehyde 3-phosphate is not a substrate.-!-Forms part of the pyridoxal-5'-phosphate cofactor biosynthesis pathway in Escherichia coli, along with EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. | D-erythrose 4-phosphate + H2O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Vitamin B6 metabolism;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1106825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASQVMR MGYG000002528_01838;MGYG000000028_01623 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,268VG@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Involved in the binding of tRNA to the ribosomes 1.0 rpsJ 1.0 - 1.0 - 1.0 ko:K02946 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 169105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394410 0 664528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1004572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3153166 0 2038876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASS(Methyl[S](Ser->Thr)ESFGYNEDQIVSSDVIGMR MGYG000002641_00563;MGYG000000195_01135 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 965637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 997531 0 0 0 0 0 0 0 0 0 0 1044268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740312 0 0 0 0 0 0 0 0 0 0 1096555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 528038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASSESFGYNED(Asp->Asn)QIVSSDVIGMR MGYG000002641_00563;MGYG000000195_01135 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 674895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASSESFGYNEDPIVSSDVIGMR MGYG000001157_00577 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540775|m__MGYG000001157 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 1202376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASSESFGYNEDQIVSSDVIGMR MGYG000002641_00563;MGYG000000195_01135 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 411828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASSESFGYTEEQLVSSDVIGMR MGYG000004732_01055 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__|m__MGYG000004732 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 591895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASSHTGAIASSDSAVEALFR MGYG000004876_01301;MGYG000000224_00594;MGYG000002438_02772;MGYG000000098_00437;MGYG000002549_03206;MGYG000002561_00294;MGYG000001346_02091;MGYG000003681_02187;MGYG000003351_03484;MGYG000004848_00129;MGYG000000196_01926;MGYG000000236_03757 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,4NFTI@976|Bacteroidetes,2FNSJ@200643|Bacteroidia,4ANVS@815|Bacteroidaceae 0.8333333333333334 976|Bacteroidetes 1.0 C 1.0 CoA binding domain protein 0.9166666666666666 - 1.0 - 1.0 - 1.0 ko:K09181 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ATP-grasp_5,CoA_binding_2,Succ_CoA_lig 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 1359224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2457551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -AASSNTISSNVMGSVHYSSPEQVR MGYG000000184_01368;MGYG000000133_01144;MGYG000000301_01423 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3XZC8@572511|Blautia 1.0 186801|Clostridia 1.0 KLT 1.0 Psort location CytoplasmicMembrane, score 1.0 prkC 1.0 - 1.0 2.7.11.1 1.0 ko:K12132 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01001 1.0 - 1.0 - 1.0 - 1.0 PASTA,PBP1_TM,Pkinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 non-specific serine/threonine protein kinase. threonine-specific protein kinase. This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.-!-Formerly EC 2.7.1.37 and EC 2.7.1.70. (1) ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]. (2) ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl- [protein]. 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317774 714241 0 0 0 0 0 590276 670939 0 0 746994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 978367 0 0 606918 0 300868 -AAST(Thr->Asn)ESFGYNTDEIVSSDIVGMR MGYG000000038_02185;MGYG000001602_01805;MGYG000002279_00557;MGYG000001008_00728 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Carbon metabolism;Alzheimer disease;Metabolic pathways;Glycolysis / Gluconeogenesis;Biosynthesis of amino acids;Microbial metabolism in diverse environments;Biosynthesis of secondary metabolites;HIF-1 signaling pathway;Carbon fixation in photosynthetic organisms 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1502480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -SLVDGHVIMPLPTYYGAN(Deamidated)GDGATHQSNEWITGK MGYG000000022_00233;MGYG000004679_00657 species d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C 1.0 COG1653@1|root,COG1653@2|Bacteria,1TR4M@1239|Firmicutes,24BFM@186801|Clostridia,3WJ7Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K02027,ko:K10192 1.0 ko02010,map02010 1.0 M00202,M00207 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1,3.A.1.1.11 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330963 0 0 0 0 1399475 0 0 0 0 318836 0 0 0 0 0 1347527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1215878 0 0 0 0 0 0 0 0 0 1473692 0 0 0 0 0 695220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4530182 0 0 0 0 3069480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18966554 0 0 0 0 243411 0 0 0 0 0 7201751 0 0 0 0 -TLIENNGTIDSIDEWGKR MGYG000000022_01085;MGYG000004679_00739 species d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C 1.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3WK85@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds together with S18 to 16S ribosomal RNA 1.0 rpsF 1.0 - 1.0 - 1.0 ko:K02990 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746164 0 0 0 0 462028 0 0 0 0 444629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 948052 0 0 0 0 0 0 0 0 0 444045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1426430 0 0 0 0 888729 0 0 0 0 1055571 0 0 0 0 0 0 0 0 0 0 -TTGNLDKDTEEALK MGYG000004679_00015;MGYG000000022_01422 species d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Photosynthesis;Metabolic pathways;Oxidative phosphorylation 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 655425 0 0 0 0 585857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1462352 0 0 0 0 0 0 0 0 0 1558678 0 0 0 0 0 0 0 0 0 0 -VC(Carbamidomethyl)KFDAIHIVDGVAK MGYG000000022_00023;MGYG000004679_00428 species d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C 1.0 COG1149@1|root,COG2878@1|root,COG1149@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,3WIFS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 electron transport complex, RnfABCDGE type, B subunit 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_13,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 529292 0 0 0 0 495675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263045 0 0 0 0 0 0 0 0 0 87957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361892 0 0 0 0 592509 0 0 0 0 100655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 834618 0 0 0 0 783555 0 0 0 0 574000 0 0 0 0 0 0 0 0 0 0 -VYELTAGKNPGE(Glu->Asp)VNIR MGYG000000333_01481;MGYG000003073_00897 species d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp002232035 1.0 COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria,4CUZS@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Arginine deiminase 1.0 arcA 1.0 - 1.0 3.5.3.6 1.0 ko:K01478 1.0 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 1.0 - 1.0 R00552 1.0 RC00177 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Amidinotransf 1.0 - 1.0 - 1.0 - 1.0 - 1.0 arginine deiminase. arginine dihydrolase. Also acts on canavanine. H2O + L-arginine = L-citrulline + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis;Metabolic pathways;Biosynthesis of secondary metabolites 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2324140 0 2568372 0 0 0 2234872 0 0 0 0 0 0 0 0 0 0 2100692 0 0 0 0 0 0 0 0 0 3043193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1785692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2861803 0 0 0 0 0 0 0 0 0 0 4659421 0 0 0 0 2399718 0 0 0 0 0 0 2942990 0 0 0 0 0 0 0 0 0 2709039 0 0 0 0 -VPAEQYPEALQK MGYG000004679_00767;MGYG000000022_02299 species d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C 1.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3WGYV@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Galactose-1-phosphate uridyl transferase, C-terminal domain 1.0 galT 1.0 - 1.0 2.7.7.12 1.0 ko:K00965 1.0 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 1.0 M00362,M00554,M00632 1.0 R00955 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GalP_UDP_tr_C,GalP_UDP_transf 1.0 - 1.0 - 1.0 - 1.0 - 1.0 UDP-glucose--hexose-1-phosphate uridylyltransferase. uridylyl removing enzyme. - alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose. 1.0 1.0 1.0 1.0 Galactose metabolism;Prolactin signaling pathway;Metabolic pathways;Amino sugar and nucleotide sugar metabolism 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550589 0 0 0 0 571231 0 0 0 0 544166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692780 0 0 0 0 1180459 0 0 0 0 855953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262042 0 0 0 0 723726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -LGAC(Carbamidomethyl)NVANAQQC(Carbamidomethyl)VPISMTGR MGYG000000022_00233;MGYG000004679_00657 species d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C 1.0 COG1653@1|root,COG1653@2|Bacteria,1TR4M@1239|Firmicutes,24BFM@186801|Clostridia,3WJ7Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K02027,ko:K10192 1.0 ko02010,map02010 1.0 M00202,M00207 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1,3.A.1.1.11 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 none 1.0 238148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339254 0 340761 0 0 0 0 350802 259787 0 0 0 420422 0 0 0 0 393943 0 0 0 0 0 1074976 114887 490331 744373 0 411139 289871 0 0 0 0 0 0 0 0 497230 0 4159366 483458 0 0 0 5104198 499224 908884 543229 0 4034257 504869 0 301351 0 453845 472004 0 133274 554715 545175 794668 592343 504952 421563 0 683587 803164 0 0 0 0 0 0 0 0 628806 0 2602120 449767 0 0 622278 3015620 857750 712124 922218 0 3242619 808199 0 678483 0 715835 551780 0 538488 572679 756399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275596 0 0 0 0 0 0 0 0 0 0 0 0 0 585950 1197106 1562387 1202389 0 1036965 1174950 0 0 0 0 0 0 0 0 954172 0 6168093 994442 0 0 701861 6810676 785736 1776025 704493 0 7150218 1643165 0 963240 0 1564173 1219747 0 1337387 746745 1205649 +Sequence Proteins LCA_level Taxon Taxon_prop eggNOG_OGs eggNOG_OGs_prop max_annot_lvl max_annot_lvl_prop COG_category COG_category_prop eggNOG_Description eggNOG_Description_prop Gene Gene_prop GOs GOs_prop EC EC_prop KEGG_ko KEGG_ko_prop KEGG_Pathway KEGG_Pathway_prop KEGG_Module KEGG_Module_prop KEGG_Reaction KEGG_Reaction_prop KEGG_rclass KEGG_rclass_prop BRITE BRITE_prop KEGG_TC KEGG_TC_prop CAZy CAZy_prop BiGG_Reaction BiGG_Reaction_prop PFAMs PFAMs_prop dbcan_EC dbcan_EC_prop dbcan_HMMER dbcan_HMMER_prop dbcan_eCAMI dbcan_eCAMI_prop dbcan_DIAMOND dbcan_DIAMOND_prop protein_id protein_id_prop EC_DE EC_AN EC_CC EC_CA EC_DE_prop EC_AN_prop EC_CC_prop EC_CA_prop KEGG_Pathway_name KEGG_Pathway_name_prop KEGG_ko_name KEGG_ko_name_prop None None_prop Intensity_V1_01 Intensity_V1_02 Intensity_V1_03 Intensity_V1_04 Intensity_V1_05 Intensity_V1_06 Intensity_V1_07 Intensity_V1_08 Intensity_V1_09 Intensity_V1_10 Intensity_V1_11 Intensity_V1_12 Intensity_V1_13 Intensity_V1_14 Intensity_V1_15 Intensity_V1_16 Intensity_V1_17 Intensity_V1_18 Intensity_V1_19 Intensity_V1_20 Intensity_V1_21 Intensity_V1_22 Intensity_V1_23 Intensity_V1_24 Intensity_V1_25 Intensity_V1_26 Intensity_V1_27 Intensity_V1_28 Intensity_V1_29 Intensity_V1_30 Intensity_V1_31 Intensity_V1_32 Intensity_V1_33 Intensity_V1_34 Intensity_V1_35 Intensity_V1_36 Intensity_V1_37 Intensity_V1_38 Intensity_V2_01 Intensity_V2_02 Intensity_V2_03 Intensity_V2_04 Intensity_V2_05 Intensity_V2_06 Intensity_V2_07 Intensity_V2_08 Intensity_V2_09 Intensity_V2_10 Intensity_V2_11 Intensity_V2_12 Intensity_V2_13 Intensity_V2_14 Intensity_V2_15 Intensity_V2_16 Intensity_V2_17 Intensity_V2_18 Intensity_V2_19 Intensity_V2_20 Intensity_V2_21 Intensity_V2_22 Intensity_V2_23 Intensity_V2_24 Intensity_V2_25 Intensity_V2_26 Intensity_V2_27 Intensity_V2_28 Intensity_V2_29 Intensity_V2_30 Intensity_V2_31 Intensity_V2_32 Intensity_V2_33 Intensity_V2_34 Intensity_V2_35 Intensity_V2_36 Intensity_V2_37 Intensity_V2_38 Intensity_V3_01 Intensity_V3_02 Intensity_V3_03 Intensity_V3_04 Intensity_V3_05 Intensity_V3_06 Intensity_V3_07 Intensity_V3_08 Intensity_V3_09 Intensity_V3_10 Intensity_V3_11 Intensity_V3_12 Intensity_V3_13 Intensity_V3_14 Intensity_V3_15 Intensity_V3_16 Intensity_V3_17 Intensity_V3_18 Intensity_V3_19 Intensity_V3_20 Intensity_V3_21 Intensity_V3_22 Intensity_V3_23 Intensity_V3_24 Intensity_V3_25 Intensity_V3_26 Intensity_V3_27 Intensity_V3_28 Intensity_V3_29 Intensity_V3_30 Intensity_V3_31 Intensity_V3_32 Intensity_V3_33 Intensity_V3_34 Intensity_V3_35 Intensity_V3_36 Intensity_V3_37 Intensity_V3_38 Intensity_V4_01 Intensity_V4_02 Intensity_V4_03 Intensity_V4_04 Intensity_V4_05 Intensity_V4_06 Intensity_V4_07 Intensity_V4_08 Intensity_V4_09 Intensity_V4_10 Intensity_V4_11 Intensity_V4_12 Intensity_V4_13 Intensity_V4_14 Intensity_V4_15 Intensity_V4_16 Intensity_V4_17 Intensity_V4_18 Intensity_V4_19 Intensity_V4_20 Intensity_V4_21 Intensity_V4_22 Intensity_V4_23 Intensity_V4_24 Intensity_V4_25 Intensity_V4_26 Intensity_V4_27 Intensity_V4_28 Intensity_V4_29 Intensity_V4_30 Intensity_V4_31 Intensity_V4_32 Intensity_V4_33 Intensity_V4_34 Intensity_V4_35 Intensity_V4_36 Intensity_V4_37 Intensity_V4_38 Intensity_V5_01 Intensity_V5_02 Intensity_V5_03 Intensity_V5_04 Intensity_V5_05 Intensity_V5_06 Intensity_V5_07 Intensity_V5_08 Intensity_V5_09 Intensity_V5_10 Intensity_V5_11 Intensity_V5_12 Intensity_V5_13 Intensity_V5_14 Intensity_V5_15 Intensity_V5_16 Intensity_V5_17 Intensity_V5_18 Intensity_V5_19 Intensity_V5_20 Intensity_V5_21 Intensity_V5_22 Intensity_V5_23 Intensity_V5_24 Intensity_V5_25 Intensity_V5_26 Intensity_V5_27 Intensity_V5_28 Intensity_V5_29 Intensity_V5_30 Intensity_V5_31 Intensity_V5_32 Intensity_V5_33 Intensity_V5_34 Intensity_V5_35 Intensity_V5_36 Intensity_V5_37 Intensity_V5_38 +(3sulfo)DNTEELIALIK MGYG000000245_00850 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp003470905|m__MGYG000000245 1.0 COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Saccharopine dehydrogenase 1.0 LYS1 1.0 - 1.0 1.5.1.7 1.0 ko:K00290 1.0 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 1.0 M00030,M00032 1.0 R00715 1.0 RC00217,RC01532 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Sacchrp_dh_C,Sacchrp_dh_NADP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000245_00850 1.0 saccharopine dehydrogenase (NAD(+), L-lysine-forming). lysine-2-oxoglutarate reductase. - H2O + L-saccharopine + NAD(+) = 2-oxoglutarate + H(+) + L-lysine + NADH. 1.0 1.0 1.0 1.0 Lysine biosynthesis|Lysine degradation|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00290:LYS1; saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:1.5.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1765523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6840189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(AccQTag)DGPMPQTNEHVLLAR MGYG000004756_01173;MGYG000003279_00951;MGYG000004658_01205;MGYG000001562_01075 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004756_01173 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76460 0 69417 0 0 0 0 383638 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143519 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87296 0 0 0 0 0 0 0 0 0 5068132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3037157 0 3672570 0 0 0 0 4889995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(AccQTag)TINTSHVEYQTANR MGYG000000042_01421;MGYG000004756_01173;MGYG000001415_02515;MGYG000002438_02321;MGYG000004658_01205;MGYG000000053_00908;MGYG000000243_01988;MGYG000000013_02251;MGYG000004006_00433;MGYG000001562_01075;MGYG000000074_01773;MGYG000001789_00154;MGYG000003279_00951;MGYG000000273_00431;MGYG000004763_01689;MGYG000001302.1_00073;MGYG000000170_00073 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 0.5882352941176471 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 586816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1043981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 561090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 890400 0 0 0 0 0 0 0 +(Acetyl)AAATAADKAR MGYG000004733_00775;MGYG000001338_01157;MGYG000000133_00993;MGYG000000301_01128 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_00775 0.25 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 214580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 688707 0 0 0 0 0 0 0 0 0 0 675135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324053 0 0 0 0 538170 +(Acetyl)AADIVLQAAIAAGAPK MGYG000002323_02346;MGYG000000093_03243;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206;MGYG000002534_02768;MGYG000003883_03730 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.8571428571428571 1236|Gammaproteobacteria 1.0 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.8571428571428571 adhE 1.0 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_02346 0.14285714285714285 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)AAFEEAEHAAK MGYG000003509_00509;MGYG000000177_00118;MGYG000002026_00456;MGYG000003891_00390;MGYG000004769_01404;MGYG000000198_03730;MGYG000000172_04155;MGYG000004087_01663;MGYG000001434_00926;MGYG000000198_03710;MGYG000004087_01662;MGYG000001564_01103;MGYG000001311_01511;MGYG000001493_02801;MGYG000001493_02800;MGYG000003422_00075;MGYG000004713_00792 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,21YU6@1506553|Lachnoclostridium 0.5294117647058824 186801|Clostridia 0.8823529411764706 C 1.0 Rubrerythrin 0.6470588235294118 rbr3A 0.9411764705882353 - 0.9411764705882353 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.8823529411764706 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003509_00509 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1589317 0 0 1239462 0 0 0 0 1771893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)AAVDATAVSPEELQAK MGYG000003683_00301;MGYG000000756_01431;MGYG000001490_01143 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 Pyruvate formate lyase-like 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bac_luciferase,Fer4_12,Gly_radical,PFL-like,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00301 0.3333333333333333 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 773174 0 0 767183 448469 0 0 0 0 0 0 0 0 518037 0 278973 0 0 0 608751 431729 297121 0 0 478416 775435 0 0 354280 420517 382973 595021 0 0 0 495970 0 0 491081 0 0 383912 560300 0 0 0 0 0 0 0 0 991086 0 1953029 0 0 0 411717 390772 924994 0 0 467644 1091307 0 0 770886 379829 0 484333 0 0 0 525670 0 0 299097 0 0 478644 425698 0 0 0 0 0 0 0 0 513521 0 340738 0 0 0 321446 524084 409856 0 0 708519 500912 0 0 509446 572264 846166 335292 0 0 0 416130 0 0 295336 0 0 0 0 0 0 0 0 0 0 0 0 536637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340756 0 0 1069057 0 0 765116 1472911 0 0 0 0 0 0 0 0 968217 0 824316 0 0 0 641311 850234 1001691 0 0 308567 822590 0 0 1244482 768849 598786 467915 0 0 0 457288 +(Acetyl)AAYSSGKPALGVGAGNTPVIIDDTADVK MGYG000001607_02072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_B|s__Dorea_B phocaeensis|m__MGYG000001607 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001607_02072 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4161765 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)ACDKHLTEAFASAGLDSGSNWR MGYG000002670_01817 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp900546625|m__MGYG000002670 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,25VT8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002670_01817 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 578792 0 215992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)ADADIASDDAIKK MGYG000000212_00409 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG1879@1|root,COG1879@2|Bacteria,1TRBC@1239|Firmicutes,24DQX@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_00409 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 798780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1724535 0 0 0 0 0 0 1429355 0 0 0 0 0 0 0 0 0 0 0 2028680 0 0 0 0 0 902282 0 0 0 0 0 0 0 0 0 0 1322958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 862225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1020591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 636192 0 0 0 0 0 0 0 0 0 0 408871 0 +(Acetyl)AEAEDGYALK MGYG000000133_01438 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3WISX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035,ko:K13889 1.0 ko02010,ko02024,map02010,map02024 1.0 M00239,M00348 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.11 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01438 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K13889:gsiB; glutathione transport system substrate-binding protein 1.0 none 1.0 0 0 113828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1035240 0 0 0 0 351493 +(Acetyl)AEKNVEVIDKESK MGYG000002517_01393 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0835@1|root,COG0835@2|Bacteria,1V4HH@1239|Firmicutes,24JV4@186801|Clostridia 1.0 186801|Clostridia 1.0 NT 1.0 PFAM CheW domain protein 1.0 - 1.0 - 1.0 - 1.0 ko:K03408 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01393 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03408:cheW; purine-binding chemotaxis protein CheW 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 265309 0 0 0 0 444544 0 0 0 0 0 0 93126 0 0 0 0 0 0 0 0 0 0 191785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1033225 0 288363 0 0 0 0 1374348 1487389 0 0 717464 0 1310631 1614033 0 0 0 1360137 0 0 0 0 0 1496974 1276268 1402839 0 0 0 0 0 438866 771690 1059150 0 1341284 294451 0 0 880818 0 0 0 0 0 0 0 0 575258 0 0 454520 0 0 0 0 0 0 0 0 0 0 604672 388554 0 0 0 0 0 648090 0 0 0 0 752760 +(Acetyl)AEVEADLNTLK(Xlink_BuUrBu[213]) MGYG000000179_03775 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,21Y9B@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03775 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 506604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460804 0 0 0 0 0 0 493151 0 555919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1166024 0 0 0 0 0 0 0 640261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1225519 0 0 768065 0 0 0 0 658409 0 0 0 0 0 0 0 0 0 0 1117274 0 0 0 0 0 0 0 0 752290 0 886018 0 0 0 0 903166 0 0 3236265 0 0 3146181 0 0 0 0 1070232 0 0 0 0 0 0 0 0 0 0 5298264 0 5910386 0 0 0 0 0 0 1773916 0 8081219 0 0 0 0 2772530 +(Acetyl)AGVKPEQVDEVLM(Oxidation)GC(Carbamidomethyl)VIQAAQGQNVAR MGYG000001711_01126;MGYG000002517_00540 domain d__Bacteria 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,3VP0M@526524|Erysipelotrichia 0.5 526524|Erysipelotrichia 0.5 I 1.0 Thiolase, C-terminal domain 0.5 - 0.5 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001711_01126 0.5 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1011847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)AGVKPEQVDEVLMGC(Carbamidomethyl)VIQAAQGQNVAR MGYG000001711_01126;MGYG000002517_00540 domain d__Bacteria 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,3VP0M@526524|Erysipelotrichia 0.5 526524|Erysipelotrichia 0.5 I 1.0 Thiolase, C-terminal domain 0.5 - 0.5 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001711_01126 0.5 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)AHIEKQAGELQEK MGYG000002515_03186 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia fergusonii|m__MGYG000002515 1.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,1RNEV@1236|Gammaproteobacteria,3WV8F@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_03186 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)AIADLDKQPDSVSSVLK MGYG000002504_02331;MGYG000002494_03392 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 2D4RX@1|root,2SW2Q@2759|Eukaryota 0.5 2759|Eukaryota 0.5 S 0.5 helix_turn_helix isocitrate lyase regulation 0.5 - 0.5 - 0.5 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 HTH_IclR,IclR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002504_02331 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1221210 0 0 0 1599123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1750921 0 0 0 0 1994325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 883762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1233190 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379092 0 0 0 0 0 0 0 0 0 +(Acetyl)AILATAQEC(Carbamidomethyl)NSPVILGVSEGAGK MGYG000003335_01155 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__GCA-900066135|s__GCA-900066135 sp900543575|m__MGYG000003335 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZ5J@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003335_01155 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)AKEKFDR MGYG000004756_01173;MGYG000001415_02515;MGYG000002438_02321;MGYG000004658_01205;MGYG000004288_00862;MGYG000002972_00178;MGYG000003516_01606;MGYG000003542_01415;MGYG000001562_01075;MGYG000000045_02616;MGYG000000254_02569;MGYG000000074_01773;MGYG000003279_00951;MGYG000001470_03722;MGYG000000044_01721;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000000223_03134;MGYG000001400_03001 life d__Bacteria 0.9474 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 0.47368421052631576 976|Bacteroidetes 0.631578947368421 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.8421052631578947 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.9473684210526315 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004756_01173 0.05263157894736842 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)AKEKFER MGYG000000042_01421;MGYG000002106_00224;MGYG000001524_01606;MGYG000001630_01142;MGYG000002485_02622;MGYG000004893_01944;MGYG000004893_00932;MGYG000003460_01161;MGYG000003155_00314;MGYG000001925_01419;MGYG000000273_00431;MGYG000001701_00473;MGYG000004763_01689;MGYG000003681_02037;MGYG000001384_04567;MGYG000001464_00103;MGYG000002281_02290;MGYG000003185_01074;MGYG000003992_01709;MGYG000003142_01879;MGYG000002528_01098;MGYG000001313_00097;MGYG000000013_02251;MGYG000003266_00392;MGYG000003583_01411;MGYG000002455_03884;MGYG000000348_00283;MGYG000003628_01000;MGYG000001485_02164;MGYG000000034_01346;MGYG000001141_02439;MGYG000002930_00867;MGYG000003142_01865;MGYG000000196_03974;MGYG000003375_00698;MGYG000004573_00004;MGYG000001661_02666;MGYG000003851_00676;MGYG000002762_01733;MGYG000000121_02189;MGYG000001789_00154;MGYG000001567_01738;MGYG000000182_00585;MGYG000000054_03933;MGYG000000236_01807;MGYG000000098_02017;MGYG000002291_02272;MGYG000003185_01053;MGYG000002556_01332;MGYG000000036_01380;MGYG000000445_01370;MGYG000001346_01533;MGYG000000243_01988;MGYG000001780_03476;MGYG000002540_03367;MGYG000001646_01118;MGYG000003073_01160;MGYG000003514_00785;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.23728813559322035 976|Bacteroidetes 0.4915254237288136 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9830508474576272 tuf 1.0 - 0.847457627118644 - 1.0 ko:K02358 0.9830508474576272 - 0.9830508474576272 - 0.9830508474576272 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9830508474576272 - 0.9830508474576272 - 1.0 - 0.9491525423728814 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.01694915254237288 - - - - 1.0 1.0 1.0 1.0 - 0.9830508474576272 K02358:tuf, TUFM; elongation factor Tu 0.9830508474576272 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)AKEKYER MGYG000000756_01285 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium sp002742445|m__MGYG000000756 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000756_01285 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)AMNADGTINRAALPAIFNPEDLNALEQALR MGYG000000243_00603 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,4AN6T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG2086 Electron transfer flavoprotein beta subunit 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00603 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)ASTIFPSFVGHTFAVHDGR MGYG000000099_02397 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3WJ9F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA 1.0 rpsS 1.0 - 1.0 - 1.0 ko:K02965 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_02397 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02965:RP-S19, RSM19, rpsS; small subunit ribosomal protein S19 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)CIEEIGTYDPTKDPSEYHVNEELAK MGYG000002492_01364;MGYG000000154_00276;MGYG000002517_01931;MGYG000004719_01372;MGYG000000271_00791;MGYG000004271_01605;MGYG000000489_02523;MGYG000002670_00836 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 - 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01364 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295652 0 482584 0 0 0 0 0 0 0 636182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 846080 568705 0 0 0 0 0 0 0 0 0 0 641349 0 0 0 0 0 0 0 0 0 565674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286571 588527 0 0 0 0 0 0 0 0 0 0 414838 0 +(Acetyl)DEAEEKNLR MGYG000004735_01252 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0747@1|root,COG0747@2|Bacteria,1VSRH@1239|Firmicutes,24Y1D@186801|Clostridia,263KC@186807|Peptococcaceae 1.0 186801|Clostridia 1.0 E 1.0 extracellular solute-binding protein, family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_01252 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 672888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)EADPAAQFEGLK MGYG000000301_01318 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900541985|m__MGYG000000301 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_01318 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183303 0 0 0 0 0 0 0 314274 0 0 0 0 0 240320 0 0 0 0 0 0 0 0 208308 0 196040 0 0 0 0 0 0 839756 1915559 0 0 778581 1251309 1135035 0 0 0 0 0 1429348 0 499378 0 0 0 0 0 1449091 0 1043388 0 0 0 0 1282282 0 924949 0 3879645 0 0 0 0 1384278 +(Acetyl)EEKEVTKPEK MGYG000003891_01624 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG1653@1|root,COG1653@2|Bacteria,1TW09@1239|Firmicutes,24BZW@186801|Clostridia,36G3C@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K17318 1.0 ko02010,map02010 1.0 M00603 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.29,3.A.1.1.9 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_01624 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K17318:lplA; putative aldouronate transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2044025 0 0 0 0 1911326 0 0 0 0 1879315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1139474 0 0 0 0 0 0 0 0 0 773022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)EENAELLPGGGSK MGYG000000002_03137 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A faecis|m__MGYG000000002 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439,ko:K17202 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212,M00590 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000002_03137 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein|K17202:eryG; erythritol transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 1042388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235491 0 668315 0 0 0 0 0 360247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176215 0 0 0 0 0 740974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)EGTFTPADSYDVGER MGYG000003891_00348 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG4166@1|root,COG4166@2|Bacteria 1.0 2|Bacteria 1.0 E 1.0 transmembrane transport 1.0 - 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 BACON,DUF4374,DUF4488,DUF5011,F5_F8_type_C,M60-like_N,Peptidase_M60,SBP_bac_5,Sulfatase,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_00348 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 513947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1311449 0 0 0 0 2144027 0 0 0 0 1911931 0 0 0 0 470425 0 0 0 0 427336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)EGVANKDKPLVWFNR MGYG000004735_00164 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00164 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7513173 0 0 0 0 0 0 0 1975768 0 0 0 976119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)EITSIVDGPISGEVK MGYG000000213_03703;MGYG000001617_04130;MGYG000000077_02122;MGYG000000262_01857;MGYG000000153_01716;MGYG000004785_01105;MGYG000002312_00278;MGYG000000159_02953;MGYG000000135_04104;MGYG000000179_02421;MGYG000004891_03103;MGYG000002492_02243;MGYG000003695_03041;MGYG000003500_00962;MGYG000004879_02429;MGYG000000153_02578;MGYG000001186_00767;MGYG000001338_02857;MGYG000000133_02555;MGYG000004548_00336;MGYG000004296_01841 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,3XYWX@572511|Blautia 0.38095238095238093 186801|Clostridia 1.0 H 0.9047619047619048 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000213_03703 0.047619047619047616 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00616:TALDO1, talB, talA; transaldolase [EC:2.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1389758 0 0 0 1535233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 731669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)FTSGNC(Carbamidomethyl)YGIIGAN(Deamidated)GAGK MGYG000003363_03180;MGYG000004876_03090;MGYG000004899_00018;MGYG000000196_03902;MGYG000001313_01281;MGYG000001346_02987;MGYG000000236_01135 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0488@1|root,COG0488@2|Bacteria,4NEHU@976|Bacteroidetes,2FMW7@200643|Bacteroidia,4AKW8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ABC_tran,ABC_tran_Xtn 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003363_03180 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)GEEGGAGVAKEDLK MGYG000004733_00545 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia,3Y2EG@572511|Blautia 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate-binding protein PnrA-like 1.0 - 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_00545 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07335:bmpA, bmpB, tmpC; basic membrane protein A and related proteins 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1184458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)GGGVRPGFEGGQM(Oxidation)PLFR MGYG000003368_00842 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Tissierellales|f__Peptoniphilaceae|g__Finegoldia|s__Finegoldia sp900766215|m__MGYG000003368 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,22HCT@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003368_00842 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3876412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)GGGVRPGFEGGQMPLYR MGYG000002528_01858;MGYG000000028_01603 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,268S2@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01858 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3695107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)GKVAPDFELVK MGYG000000196_04914 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04914 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1532316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)ILTGAGQKSFVAGADIGEMSTLTK MGYG000001809_02346 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eisenbergiella|s__|m__MGYG000001809 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,36EDS@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 1.0 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001809_02346 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1343649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224456 0 0 0 0 0 0 0 +(Acetyl)IYYQSDC(Carbamidomethyl)NLSLLDGK MGYG000000187_00168 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,25VBQ@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000187_00168 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 708681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KAALIER MGYG000003899_00855 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539945|m__MGYG000003899 1.0 COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,3WGG6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O 1.0 hcp 1.0 - 1.0 1.7.99.1 1.0 ko:K05601 1.0 ko00910,map00910 1.0 - 1.0 R00143 1.0 RC02797 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Prismane 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003899_00855 1.0 hydroxylamine reductase. hydroxylamine (acceptor) reductase. Reduced pyocyanine, methylene blue and flavins act as donors for the reduction of hydroxylamine.-!-May be identical to EC 1.7.2.1. A + H2O + NH4(+) = AH2 + H(+) + hydroxylamine. 1.0 1.0 1.0 1.0 Nitrogen metabolism 1.0 K05601:hcp; hydroxylamine reductase [EC:1.7.99.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 559637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KAEGGIER MGYG000000142_02504;MGYG000001338_02427;MGYG000000184_00683;MGYG000000184_00682;MGYG000000201_00496 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3XZDK@572511|Blautia 0.4 186801|Clostridia 1.0 C 1.0 acetyl-CoA decarbonylase synthase complex subunit beta 0.6 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_02504 0.2 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 162393 0 0 0 0 0 0 0 0 0 0 0 0 0 960545 0 0 0 0 0 0 509083 0 0 0 0 0 0 0 0 0 0 0 0 1064367 0 0 0 1839741 0 0 0 0 0 0 0 0 0 0 0 0 0 1623087 0 0 0 0 0 0 481455 0 1238831 0 1324331 0 0 0 0 0 0 0 0 1804836 1877670 1524429 0 1672282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363856 0 1366772 0 0 0 0 0 0 0 0 1164435 1245235 1029536 0 2328944 0 0 0 0 0 0 0 0 0 0 0 0 0 1960383 0 0 0 0 0 0 0 0 3003223 0 0 0 0 0 0 0 0 0 0 2009363 2244257 1727692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KAGHYAVGQFNINNLEWTK MGYG000000142_01854;MGYG000000249_00065;MGYG000000258_00162;MGYG000001637_01196;MGYG000001374_02205;MGYG000002528_01756 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia 0.5 186801|Clostridia 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 0.8333333333333334 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01854 0.16666666666666666 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1216331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KAPAAPK MGYG000004757_01023 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__UBA6398|s__UBA6398 sp900555645|m__MGYG000004757 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000004757_01023 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KEGHYAVGQFNINNLEWTK MGYG000001186_01756 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp900547695|m__MGYG000001186 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001186_01756 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 1263256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KELLGK MGYG000001346_01043;MGYG000000196_00547;MGYG000004876_02935;MGYG000003681_00897;MGYG000002720_01363;MGYG000004797_02532;MGYG000000243_01228;MGYG000002478_02960;MGYG000001602_01322 domain d__Bacteria 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 0.5555555555555556 976|Bacteroidetes 0.7777777777777778 J 0.6666666666666666 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 0.5555555555555556 rpsA 0.5555555555555556 - 0.8888888888888888 - 0.5555555555555556 ko:K02945 0.5555555555555556 ko03010,map03010 0.5555555555555556 M00178 0.5555555555555556 - 0.6666666666666666 - 0.6666666666666666 br01610,ko00000,ko00001,ko00002,ko03011 0.5555555555555556 - 1.0 - 1.0 - 0.8888888888888888 S1 0.5555555555555556 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_01043 0.1111111111111111 - - - - 0.5555555555555556 0.5555555555555556 0.5555555555555556 0.5555555555555556 Ribosome 0.5555555555555556 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 0.5555555555555556 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KEWGLGNINK MGYG000000781_01762 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900541515|m__MGYG000000781 1.0 COG0280@1|root,COG0280@2|Bacteria,4NGX5@976|Bacteroidetes,2FMKY@200643|Bacteroidia,4AK60@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625,ko:K13788 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000781_01762 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00625:pta; phosphate acetyltransferase [EC:2.3.1.8]|K13788:pta; phosphate acetyltransferase [EC:2.3.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6295341 0 0 0 0 0 0 0 0 0 0 0 0 7698257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KGAMAY(O-pinacolylmethylphosphonate)LK MGYG000003374_01704 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella bivia|m__MGYG000003374 1.0 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane 1.0 hppA 1.0 - 1.0 3.6.1.1 1.0 ko:K15987 1.0 ko00190,map00190 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 3.A.10.1 1.0 - 1.0 - 1.0 H_PPase,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003374_01704 1.0 inorganic diphosphatase. pyrophosphate phosphohydrolase. Specificity varies with the source and with the activating metal ion.-!-The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9. cf. EC 7.1.3.1. diphosphate + H2O = H(+) + 2 phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation 1.0 K15987:hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 651210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KGGVEPQSETVW(Dioxidation)R MGYG000002994_01409;MGYG000001658_02289;MGYG000003142_01866;MGYG000001300_00281;MGYG000004769_00436;MGYG000002619_00484;MGYG000002926_00231;MGYG000000089_01902;MGYG000000377_01099;MGYG000000392_00967;MGYG000003937_01028;MGYG000002040_01211;MGYG000004471_00745;MGYG000000084_01999;MGYG000000099_01235;MGYG000002098_01617;MGYG000001255_01100;MGYG000004642_00845;MGYG000002641_00068;MGYG000000371_01542;MGYG000000118_01086;MGYG000000039_00482;MGYG000002173_00226;MGYG000002224_01124;MGYG000000022_02282;MGYG000001733_00476;MGYG000004221_01652;MGYG000004285_00598;MGYG000002143_01658;MGYG000002720_00091;MGYG000004482_01536;MGYG000002965_00479;MGYG000000036_01379;MGYG000001685_01865;MGYG000002057_01067;MGYG000002545_02503;MGYG000001157_01851;MGYG000000258_00265;MGYG000004475_00888;MGYG000000989_00159;MGYG000001651_00900;MGYG000004525_01293;MGYG000004707_00950 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.46511627906976744 186801|Clostridia 0.9302325581395349 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000002994_01409 0.023255813953488372 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KGGVEPQSETVWR MGYG000002994_01409;MGYG000001658_02289;MGYG000003142_01866;MGYG000001300_00281;MGYG000004769_00436;MGYG000002619_00484;MGYG000002926_00231;MGYG000000089_01902;MGYG000000377_01099;MGYG000000392_00967;MGYG000003937_01028;MGYG000002040_01211;MGYG000004471_00745;MGYG000000084_01999;MGYG000000099_01235;MGYG000002098_01617;MGYG000001255_01100;MGYG000004642_00845;MGYG000002641_00068;MGYG000000371_01542;MGYG000000118_01086;MGYG000000039_00482;MGYG000002173_00226;MGYG000002224_01124;MGYG000000022_02282;MGYG000001733_00476;MGYG000004221_01652;MGYG000004285_00598;MGYG000002143_01658;MGYG000002720_00091;MGYG000004482_01536;MGYG000002965_00479;MGYG000000036_01379;MGYG000001685_01865;MGYG000002057_01067;MGYG000002545_02503;MGYG000001157_01851;MGYG000000258_00265;MGYG000004475_00888;MGYG000000989_00159;MGYG000001651_00900;MGYG000004525_01293;MGYG000004707_00950 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.46511627906976744 186801|Clostridia 0.9302325581395349 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000002994_01409 0.023255813953488372 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 524044 0 0 0 0 0 0 11088508 0 0 0 0 0 0 0 0 0 0 10225856 0 0 0 7510769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5620292 4933531 8226102 5116219 0 6915845 0 6351751 0 6535331 0 0 0 6408865 5799244 0 5230126 0 0 0 9077869 0 0 0 7413564 6826617 6574068 0 0 7739908 6119342 6236851 5873368 0 7076971 7536952 7470122 6426953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KGLITVLSK MGYG000000281_03142 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnoclostridium_A|s__Lachnoclostridium_A sp003464085|m__MGYG000000281 1.0 COG1715@1|root,COG1715@2|Bacteria,1R5BT@1224|Proteobacteria,2U0MJ@28211|Alphaproteobacteria,2K7S3@204457|Sphingomonadales 1.0 204457|Sphingomonadales 1.0 V 1.0 Restriction endonuclease 1.0 - 1.0 - 1.0 - 1.0 ko:K07448 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02048 1.0 - 1.0 - 1.0 - 1.0 Mrr_cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000281_03142 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07448:mrr; restriction system protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9670300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KIALTLY(Tyr->Val)K MGYG000001464_01830 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium|s__Fusobacterium polymorphum|m__MGYG000001464 1.0 COG0220@1|root,COG1519@1|root,COG0220@2|Bacteria,COG1519@2|Bacteria,378F3@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 M 1.0 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA 1.0 trmB 1.0 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 1.0 2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 1.0 ko:K02527,ko:K03439 1.0 ko00540,ko01100,map00540,map01100 1.0 M00060,M00080 1.0 R04658,R05074,R09763 1.0 RC00009,RC00077,RC00247 1.0 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005,ko03016 1.0 - 1.0 GT30 1.0 - 1.0 Glycos_transf_N,Methyltransf_4 1.0 - 1.0 GT30 1.0 GT30 1.0 GT30 1.0 MGYG000001464_01830 1.0 tRNA (guanine(46)-N(7))-methyltransferase. | lipid IVA 3-deoxy-D-manno-octulosonic acid transferase. | (Kdo)-lipid IVA 3-deoxy-D-manno-octulosonic acid transferase. | (Kdo)2-lipid IVA (2-8) 3-deoxy-D-manno-octulosonic acid transferase. | (Kdo)3-lipid IVA (2-4) 3-deoxy-D-manno-octulosonic acid transferase. tRNA guanine 7-methyltransferase. | lipid IVA KDO transferase. | Kdo transferase. The enzyme specifically methylates guanine(46) at N(7) in tRNA. | The enzyme from Escherichia coli is bifunctional and transfers two 3-deoxy-D-manno-oct-2-ulosonate residues to lipid IVA (cf. EC 2.4.99.13).-!-The monofunctional enzymes from Bordetella pertusis, Aquifex aeolicus and Haemophilus influenzae catalyze the transfer of a single 3-D- manno-oct-2-ulosonate residue from CMP-3-D-manno-oct-2-ulosonate to lipid IVA.-!-The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno- oct-2-ulosonate residues and generate genus-specific epitopes. | The enzyme from Escherichia coli is bifunctional and transfers two 3-deoxy-D-manno-oct-2-ulosonate residues to lipid IVA (cf. EC 2.4.99.12).-!-The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno- oct-2-ulosonate residues and generate genus-specific epitopes. | The enzymes from Chlamydia transfer three or more 3-deoxy-D-manno- octulosonate residues and generate genus-specific epitopes. | The enzyme from Chlamydia psittaci transfers four KDO residues to lipid A, forming a branched tetrasaccharide with the structure alpha- KDO-(2,8)-[alpha-KDO-(2,4)]-alpha-KDO-(2,4)-alpha-KDO (cf. EC 2.4.99.12, EC 2.4.99.13 and EC 2.4.99.14). guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)- methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine. | a lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha- Kdo-(2->6)-lipid IVA + CMP + H(+). | an alpha-Kdo-(2->6)-lipid IVA + CMP-3-deoxy-beta-D-manno-octulosonate = an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+). | alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta- D-manno-octulosonate = alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha- Kdo-(2->6)-lipid IVA (E. coli) + CMP + H(+). | alpha-Kdo-(2->8)-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) + CMP-3-deoxy-beta-D-manno-octulosonate = alpha-Kdo-(2->8)-[alpha- Kdo-(2->4)]-alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA + CMP + H(+). 1.0 1.0 1.0 1.0 Lipopolysaccharide biosynthesis|Metabolic pathways 1.0 K02527:kdtA, waaA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]|K03439:trmB, METTL1, TRM8; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1385782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KIETISK MGYG000001683_01572 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Frisingicoccus|s__|m__MGYG000001683 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,21XZX@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Formyltetrahydrofolate synthetase 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001683_01572 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01938:fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4576073 0 0 0 0 0 +(Acetyl)KLALNLR MGYG000001423_01460;MGYG000004714_00478;MGYG000004699_00365 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae 1.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,36EKQ@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 - 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001423_01460 0.3333333333333333 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03043:rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KLTVLSK MGYG000004479_01006;MGYG000001783_01851;MGYG000002478_04546;MGYG000004797_02951;MGYG000001599_02324;MGYG000000243_00072;MGYG000000781_01199;MGYG000004763_02178 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,2FMXC@200643|Bacteroidia,4ANTX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family 1.0 lysS 1.0 - 1.0 6.1.1.6 1.0 ko:K04567 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03658 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DUF4332,tRNA-synt_2,tRNA_anti-codon 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004479_01006 0.125 lysine--tRNA ligase. lysyl-tRNA synthetase. - ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K04567:KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] 1.0 none 1.0 709879 885023 842043 0 0 0 0 0 0 1027582 848331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 842674 793260 0 661839 0 0 1605569 1131753 0 629290 0 708724 910518 627413 742474 857641 0 0 0 0 0 0 758706 1085602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822070 607125 0 805398 0 0 859030 1010491 0 792579 0 759621 851218 832059 430313 811573 0 0 0 0 0 0 1032456 932548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 749431 807937 0 505991 0 0 463485 663701 0 805829 0 909247 756326 1146274 1505930 1484497 0 0 0 0 0 0 1608643 981259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1046750 1208903 0 1357420 0 0 1366358 1759303 0 1241380 0 1010399 1391388 297286 538439 449423 0 0 0 0 0 0 255014 371957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231983 87682 0 205028 0 0 447546 326559 0 303588 0 321296 440167 +(Acetyl)KLVDELIPAVK MGYG000000022_00458;MGYG000000039_00979 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00458 0.5 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 2118017 0 0 0 0 0 0 0 0 0 0 0 871948 0 0 0 0 0 0 1013105 0 1190529 0 0 1143051 0 0 0 0 0 0 0 0 0 1073115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153409 0 0 0 0 0 504879 0 398401 0 0 0 0 0 193227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KVDAM(Oxidation)NAAGDKSVIK MGYG000001319_01320 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,36E17@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001319_01320 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KVEVTIPVK(Lys->Arg) MGYG000004719_00336 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900756925|m__MGYG000004719 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004719_00336 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K05808:hpf; ribosome hibernation promoting factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2733027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KVIPELDGK MGYG000004757_00364 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__UBA6398|s__UBA6398 sp900555645|m__MGYG000004757 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004757_00364 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KVIPELN(Deamidated)GK MGYG000001562_00044;MGYG000002540_02142;MGYG000001643_00773;MGYG000004285_00359;MGYG000002478_03999;MGYG000003697_01698;MGYG000000086_02423;MGYG000001789_00244;MGYG000003372_00674;MGYG000000243_01331;MGYG000002506_01169;MGYG000004756_01346;MGYG000003202_00946;MGYG000002905_02083 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.35714285714285715 976|Bacteroidetes 0.7142857142857143 G 0.5714285714285714 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 0.8571428571428571 - 0.8571428571428571 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.8571428571428571 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001562_00044 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040466 0 0 0 0 1310783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582414 0 0 0 0 0 0 0 0 0 1020092 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KVIPELNGK MGYG000001562_00044;MGYG000002540_02142;MGYG000001643_00773;MGYG000004285_00359;MGYG000002478_03999;MGYG000003697_01698;MGYG000000086_02423;MGYG000001789_00244;MGYG000003372_00674;MGYG000000243_01331;MGYG000002506_01169;MGYG000004756_01346;MGYG000003202_00946;MGYG000002905_02083 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.35714285714285715 976|Bacteroidetes 0.7142857142857143 G 0.5714285714285714 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 0.8571428571428571 - 0.8571428571428571 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.8571428571428571 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001562_00044 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)KVLPELNGK MGYG000001789_00244;MGYG000001562_00044;MGYG000000243_01331;MGYG000002506_01169;MGYG000000375_01483;MGYG000002478_03999;MGYG000003819_01468;MGYG000004642_01190;MGYG000001415_02219;MGYG000003202_00946;MGYG000002494_01669 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.2727272727272727 976|Bacteroidetes 0.5454545454545454 G 0.6363636363636364 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 0.8181818181818182 - 0.8181818181818182 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.8181818181818182 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001789_00244 0.09090909090909091 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1398112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)LGTGQAVAFENIDKAPEER MGYG000000198_01165 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,21XMI@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_01165 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)LLTGLPDAYGR MGYG000003683_00301;MGYG000000138_02765;MGYG000002057_00708;MGYG000002469_00869;MGYG000003420_01555;MGYG000002974_01425;MGYG000002727_01362;MGYG000001292_01825;MGYG000003452_00444;MGYG000000164_01790;MGYG000001617_02351;MGYG000001464_02452;MGYG000002438_01173;MGYG000002654_00807 domain d__Bacteria 1.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 0.2857142857142857 186801|Clostridia 0.42857142857142855 C 1.0 Pyruvate formate lyase-like 0.2857142857142857 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 0.7142857142857143 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00301 0.07142857142857142 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 605358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)M(Oxidation)GIIIKPLVTEK MGYG000000013_02234;MGYG000001378_05025;MGYG000001345_04701;MGYG000002033_01881;MGYG000002549_02923;MGYG000002478_00797;MGYG000000138_02887;MGYG000002561_02177;MGYG000001313_00072;MGYG000000243_01969;MGYG000000042_01089;MGYG000001346_01517;MGYG000000105_02006;MGYG000002455_03901;MGYG000000224_00474;MGYG000000098_02000;MGYG000003701_04696;MGYG000002438_02210;MGYG000003681_02053 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,2FT3A@200643|Bacteroidia,4ARB9@815|Bacteroidaceae 0.7894736842105263 976|Bacteroidetes 1.0 J 1.0 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome 1.0 rplW 1.0 - 1.0 - 1.0 ko:K02892 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_02234 0.05263157894736842 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02892:RP-L23, MRPL23, rplW; large subunit ribosomal protein L23 1.0 none 1.0 0 0 0 0 0 0 0 0 1137301 0 0 0 0 0 0 540516 996988 0 0 0 0 605421 0 904540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)M(Oxidation)ISAGDFR MGYG000000532_00439;MGYG000004735_00107;MGYG000000150_02633;MGYG000003335_00377;MGYG000001698_03996;MGYG000000095_00313;MGYG000000136_01173;MGYG000002445_00479;MGYG000000135_03339;MGYG000000359_00892;MGYG000004271_02006;MGYG000001315_00716;MGYG000001637_02148;MGYG000001688_01265;MGYG000000997_00192;MGYG000000153_00299;MGYG000004719_01278;MGYG000002025_02346;MGYG000000002_01173;MGYG000002989_00302;MGYG000001954_01282;MGYG000001617_04062;MGYG000000271_00872;MGYG000000141_00833;MGYG000000245_00761;MGYG000000389_00571;MGYG000003215_01007;MGYG000001367_01257;MGYG000001619_00509;MGYG000003702_00466;MGYG000000650_01785;MGYG000001247_00681;MGYG000002216_00086;MGYG000000179_03263;MGYG000002517_01016;MGYG000001065_01715;MGYG000000154_01060;MGYG000004548_01812;MGYG000000312_01121;MGYG000002247_02808 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 - 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000532_00439 0.025 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02356:efp; elongation factor P 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 546658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 494544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)MDFTLDKK MGYG000000076_01275;MGYG000003694_00879;MGYG000000136_00900;MGYG000000312_02425;MGYG000000271_02102;MGYG000004271_00233;MGYG000000389_02149;MGYG000001793_01807;MGYG000002517_00542;MGYG000000489_01025 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.8 186801|Clostridia 1.0 C 0.8 acyl-CoA dehydrogenase 0.9 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000076_01275 0.1 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 224556 0 0 0 0 0 0 270466 0 0 0 0 0 338828 476014 0 0 0 689682 616310 0 0 0 0 669778 0 318301 0 0 0 0 0 0 394690 218931 302398 432576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285590 0 0 0 0 0 219047 329982 0 0 0 736580 0 321178 366218 0 0 0 233097 366342 0 0 0 0 434427 274084 484743 0 0 0 0 0 0 171893 268094 0 668761 119842 2013481 702877 671255 0 1330157 871989 1078853 1983588 2075951 1072541 0 1425935 0 2572794 2475373 1160567 1722798 0 2060157 1905405 0 487349 0 527592 2118250 1865857 1932974 0 0 0 949886 0 1056953 1226312 1860626 1950900 2261208 822146 1332013 1069075 1822668 0 320023 1225563 1491651 979831 1445066 1874672 0 1695781 0 1791550 1722448 1538571 1647233 0 1523631 1761753 0 1100876 0 1039870 1647344 1097003 1550541 0 0 0 1243717 0 1653364 1374299 884707 1406180 1747393 1287046 +(Acetyl)MDLSNLQGAAGSTQSDNFR MGYG000002517_02854 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02854 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340200 0 0 0 0 0 0 0 0 0 0 436263 0 0 0 0 0 0 0 0 0 0 438330 0 0 0 0 0 0 0 0 0 0 0 0 483280 0 0 595785 0 0 0 0 0 0 0 0 0 0 461134 0 0 0 0 0 0 0 0 0 0 571504 0 0 +(Acetyl)MDTNSTITGR MGYG000002517_00557 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins 1.0 ribU 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ECF_trnsprt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00557 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726080 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)MINPIVK MGYG000004797_03519;MGYG000000098_03719;MGYG000000013_03985;MGYG000001306_02079;MGYG000001345_00516;MGYG000003693_00350;MGYG000000196_02452;MGYG000000042_02651;MGYG000001346_01624;MGYG000004185_01554;MGYG000002549_04587;MGYG000001337_03982;MGYG000003681_02801;MGYG000000243_02576;MGYG000000273_00377;MGYG000004763_01920;MGYG000002478_00894;MGYG000001364_02629;MGYG000000236_01868;MGYG000001378_04409 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004797_03519 0.05 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 623029 0 0 0 0 0 0 0 0 0 0 0 0 0 414141 0 0 0 0 606434 0 0 0 0 504400 0 0 0 0 0 0 0 0 0 0 0 0 0 63677 0 0 0 0 0 0 0 0 0 0 0 0 0 607361 0 0 0 0 1029591 0 0 0 0 888703 0 0 0 0 0 0 0 0 0 0 0 0 0 427020 0 0 0 0 0 0 0 0 0 0 0 0 0 89497 0 0 0 0 368423 0 0 0 0 381060 0 0 0 0 0 0 0 0 0 0 0 0 0 102070 0 0 0 0 0 0 0 0 0 0 0 0 0 128067 0 0 0 0 139482 0 0 0 0 318464 0 0 0 0 0 0 0 0 0 0 0 0 0 467164 0 0 0 0 0 0 0 0 0 0 0 0 0 897981 0 0 0 0 725188 0 0 0 0 881159 0 0 0 0 0 0 0 0 0 0 +(Acetyl)MISAGDFK MGYG000000142_02218;MGYG000000077_00445 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3XZPQ@572511|Blautia 0.5 186801|Clostridia 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 - 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_02218 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02356:efp; elongation factor P 1.0 none 1.0 0 813014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396952 0 0 0 0 0 0 0 0 1003019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1251117 0 0 0 0 0 0 0 0 1340575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488762 0 0 0 0 0 0 0 0 1441548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1237974 0 0 0 0 0 0 0 0 3278358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2228943 0 0 0 0 0 0 0 +(Acetyl)MISAGDFR MGYG000000532_00439;MGYG000004735_00107;MGYG000000150_02633;MGYG000003335_00377;MGYG000001698_03996;MGYG000000095_00313;MGYG000000136_01173;MGYG000002445_00479;MGYG000000135_03339;MGYG000000359_00892;MGYG000004271_02006;MGYG000001315_00716;MGYG000001637_02148;MGYG000001688_01265;MGYG000000997_00192;MGYG000000153_00299;MGYG000004719_01278;MGYG000002025_02346;MGYG000000002_01173;MGYG000002989_00302;MGYG000001954_01282;MGYG000001617_04062;MGYG000000271_00872;MGYG000000141_00833;MGYG000000245_00761;MGYG000000389_00571;MGYG000003215_01007;MGYG000001367_01257;MGYG000001619_00509;MGYG000003702_00466;MGYG000000650_01785;MGYG000001247_00681;MGYG000002216_00086;MGYG000000179_03263;MGYG000002517_01016;MGYG000001065_01715;MGYG000000154_01060;MGYG000004548_01812;MGYG000000312_01121;MGYG000002247_02808 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 - 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000532_00439 0.025 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02356:efp; elongation factor P 1.0 none 1.0 1816907 0 1695270 2099915 0 2126718 1383473 1782610 1930138 2309627 2021672 2889837 0 1610052 1859320 970476 1379272 0 1793133 0 0 1987855 0 1586426 1998078 2564274 1893235 0 2171940 1933280 1058183 0 1089389 1884052 1780933 1757048 1860483 1315164 715270 0 928368 826761 0 500900 821357 739224 642569 1036688 889967 1006033 0 777428 714831 752256 863064 0 609009 0 0 447883 0 591471 666080 889658 857188 0 1325975 1149076 771335 0 883443 840277 649840 710592 652568 692710 1704121 0 2349642 1304949 0 1106872 1277662 1601424 1537518 1326053 1871593 2035007 0 1878746 1531413 1849893 1683720 0 1270403 0 0 197415 0 1333832 1414656 1909452 1671686 0 1681185 1816479 1282091 0 2327411 1304081 1361997 1564201 1923192 2823580 2867747 0 1298484 3184451 0 1425609 1787384 3329717 3406085 2012363 2081358 1818494 0 3195792 3539053 1713105 2402068 0 2423761 0 0 960463 0 1052827 2738441 2448789 2942246 0 2682821 2732475 1701337 0 1634042 2472527 3007466 2701272 3668047 1335594 3661693 0 3220336 2939948 0 3318487 3155218 3061878 3977050 4351098 2255097 3105713 0 4041475 4031259 1997216 4156012 0 3225533 0 0 2924797 0 2780486 3409688 3825451 3739147 0 2345258 3294010 2689344 0 2403286 3194059 3337766 3841700 4814774 3006136 +(Acetyl)MKQDALGMIETK MGYG000003142_02726;MGYG000003142_02725 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium_J|s__Clostridium_J sp900547625|m__MGYG000003142 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 1.0 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003142_02726 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)MVSAGDFR MGYG000000233_02473;MGYG000000205_01960 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,21Y5H@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 - 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02473 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02356:efp; elongation factor P 1.0 none 1.0 528297 0 0 0 0 0 0 0 0 541333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 503038 113686 0 0 0 0 0 0 0 0 0 0 495082 0 846965 0 0 0 0 0 0 0 0 1219737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 792199 715218 0 0 0 0 0 0 0 0 0 0 570657 0 459572 0 0 0 0 0 0 0 0 170297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517170 361414 0 0 0 0 0 0 0 0 0 0 327143 0 480707 0 0 0 0 0 0 0 0 653721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478793 372324 0 0 0 0 0 0 0 0 0 0 468837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114258 97421 0 0 0 0 0 0 0 0 0 0 139162 0 +(Acetyl)MVVQHNLTAM(Oxidation)NANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.1 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.1 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339173 0 0 0 0 0 0 0 863146 0 0 0 0 0 0 577525 0 484505 0 0 0 0 0 277305 0 0 0 0 460774 0 0 623623 0 0 0 0 0 0 0 0 0 296493 0 637719 482565 0 0 0 944543 0 751220 862884 0 0 0 0 0 0 0 0 0 949419 0 0 0 0 0 494369 0 1106971 0 0 0 0 0 0 995695 0 768314 484933 0 0 0 897544 951888 0 739896 0 792687 1281347 0 760360 1149988 1359125 0 870667 1161600 0 939383 1101115 0 0 0 1565957 909658 634495 0 715423 1092625 980767 0 0 0 0 1489840 0 1183113 1088477 875181 773250 1748768 1108013 +(Acetyl)MYEDETLVC(Carbamidomethyl)R MGYG000003891_00899 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,4H597@909932|Negativicutes 1.0 909932|Negativicutes 1.0 K 1.0 Probable zinc-ribbon domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-trcl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_00899 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 900660 0 0 0 0 1109463 0 0 0 0 1204237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)NDSGVESIDDLAGKK MGYG000000133_01162 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3XYTF@572511|Blautia 1.0 186801|Clostridia 1.0 ET 1.0 COG COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain 1.0 artP 1.0 - 1.0 - 1.0 ko:K02029,ko:K02030 1.0 - 1.0 M00236 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1.3 1.0 - 1.0 - 1.0 SBP_bac_3,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01162 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02029:ABC.PA.P; polar amino acid transport system permease protein|K02030:ABC.PA.S; polar amino acid transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822414 0 0 849417 0 784490 0 853460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521487 0 0 0 0 0 0 0 +(Acetyl)QLDEAQAGDNIGALLR MGYG000002492_00344;MGYG000002517_00205;MGYG000000245_03248;MGYG000002670_00364 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00344 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)QTENVLS(Ser->Gln)GK MGYG000000205_00061 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066535|m__MGYG000000205 1.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,268E5@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system 1.0 - 1.0 - 1.0 3.6.3.31 1.0 ko:K02052,ko:K11072 1.0 ko02010,ko02024,map02010,map02024 1.0 M00193,M00299 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 3.A.1.11,3.A.1.11.1 1.0 - 1.0 - 1.0 ABC_tran,TOBE_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_00061 1.0 ABC-type polyamine transporter. polyamine-transporting ATPase. An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.-!-Does not undergo phosphorylation during the transport process.-!-A bacterial enzyme that imports putrescine and spermidine.-!-In Escherichia coli the enzyme imports spermidine preferentially.-!-Formerly EC 3.6.3.31. ATP + H2O + polyamine-[polyamine-binding protein]Side 1 = ADP + phosphate + polyamineSide 2 + [polyamine-binding protein]Side 1. 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 1.0 K02052:ABC.SP.A; putative spermidine/putrescine transport system ATP-binding protein|K11072:potA; spermidine/putrescine transport system ATP-binding protein [EC:7.6.2.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1368691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)SAFTGSASVM(Met->Xle)K MGYG000001789_02837 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002161565|m__MGYG000001789 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001789_02837 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5902843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)SAGFLTR MGYG000002492_02720;MGYG000002517_00289;MGYG000000136_01618 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 1.0 rpsI 1.0 - 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_02720 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02996:RP-S9, MRPS9, rpsI; small subunit ribosomal protein S9 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3376203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)SATPGGVVK MGYG000003142_01853 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium_J|s__Clostridium_J sp900547625|m__MGYG000003142 1.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,36IUH@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome 1.0 rplN 1.0 - 1.0 - 1.0 ko:K02874 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L14 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003142_01853 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02874:RP-L14, MRPL14, rplN; large subunit ribosomal protein L14 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3741545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3240583 0 0 0 0 0 0 0 0 0 0 3237371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)SEEHGPSSEAAPAWENYDAR MGYG000000133_00227 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,36EHU@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 Family 5 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00227 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236787 269007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1932880 2208960 0 0 0 827666 3331387 1490635 0 2723671 1797841 0 0 4763756 0 2229856 0 0 0 0 0 1417448 0 0 2310860 2002868 2649085 0 3925540 0 0 0 4476098 3268855 1898271 0 2617916 0 +(Acetyl)SEKDAAAEKTEESADETK MGYG000000133_00899 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1879@1|root,COG1879@2|Bacteria,1TSUI@1239|Firmicutes,24BR7@186801|Clostridia,26BK5@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K02058 1.0 - 1.0 M00221 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1.2 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00899 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02058:ABC.SS.S; simple sugar transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 711720 0 0 0 1249046 0 0 1561327 0 869474 0 2727184 0 750884 0 0 2318378 0 1406274 0 0 0 0 0 0 0 0 0 0 0 1136521 1445174 0 0 0 802665 +(Acetyl)SEQNNTEMAFQIQR MGYG000002494_02265;MGYG000002535_04413;MGYG000002534_00127 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,3WXY5@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 U 1.0 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA 1.0 secB 1.0 GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 1.0 - 1.0 ko:K03071 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044,ko03110 1.0 3.A.5 1.0 - 1.0 - 1.0 SecB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02265 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03071:secB; preprotein translocase subunit SecB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 672549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502892 0 1036234 627246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1007973 0 0 754296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)SEQNNTEMTFQIQR MGYG000002506_03260;MGYG000002323_04108 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,3WXY5@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 U 1.0 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA 1.0 secB 1.0 GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 1.0 - 1.0 ko:K03071 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044,ko03110 1.0 3.A.5 1.0 - 1.0 - 1.0 SecB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_03260 0.5 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03071:secB; preprotein translocase subunit SecB 1.0 none 1.0 0 371351 0 0 0 741850 544630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424141 0 766857 0 0 0 0 463352 0 0 0 0 363469 0 0 0 0 0 413808 0 0 0 698033 866523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 434791 0 269176 0 0 0 0 287608 0 0 0 0 481546 0 0 0 0 0 225090 0 0 0 0 455472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519540 0 720941 0 0 0 0 382248 0 0 0 0 473983 0 0 0 0 0 581015 0 0 0 656327 612410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 926077 0 495141 0 0 0 0 374677 0 0 0 0 899561 0 0 0 0 0 0 0 0 0 0 177496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189763 0 0 0 0 356361 0 0 0 0 149662 0 0 0 0 +(Acetyl)SETNNTQER MGYG000003891_00998 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,25WUN@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA 1.0 rpsQ 1.0 - 1.0 - 1.0 ko:K02961 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_00998 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02961:RP-S17, MRPS17, rpsQ; small subunit ribosomal protein S17 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 602947 0 0 0 0 630439 0 0 0 0 540059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)SHHHEGC(Carbamidomethyl)C(Carbamidomethyl)KHEGQPR MGYG000002506_02717 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3XNX9@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 K 1.0 transcriptional regulator 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02717 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 281194 319705 0 1583167 0 1042348 0 0 0 0 907270 0 0 0 725674 497056 427239 811898 0 0 0 0 0 0 287228 194607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67442 0 0 0 0 0 0 0 0 0 0 0 29381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35238 0 29950 0 0 0 0 16461 0 0 0 24085 29197 21619 11662 0 18667 0 0 0 0 38475 23384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)SKEKFER MGYG000000291_00377;MGYG000003184_03610;MGYG000002506_03686;MGYG000002506_02966 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,3ZITI@590|Salmonella 0.75 1236|Gammaproteobacteria 0.75 J 1.0 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.75 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000291_00377 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 1964350 0 0 0 0 0 3904428 0 0 0 0 0 0 0 0 0 0 0 0 0 4287395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1351266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5751292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3574386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5505611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)SMSDDTHNSLSTGK MGYG000002494_01908 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0685@1|root,KOG0564@2759|Eukaryota 1.0 2759|Eukaryota 1.0 E 1.0 methylenetetrahydrofolate reductase (NAD(P)H) activity 1.0 MTHFR1 1.0 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.0 1.5.1.20,3.6.4.12 1.0 ko:K00297,ko:K10901 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko03440,ko03460,map00670,map00720,map01100,map01120,map01200,map01523,map03440,map03460 1.0 M00295,M00377,M00414 1.0 R01224,R07168 1.0 RC00081 1.0 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 1.0 - 1.0 - 1.0 - 1.0 BT1,DEAD,DUF1712,EamA,Helicase_C,Homoserine_dh,Hormone_recep,MTHFR,RecQ_Zn_bind,peroxidase,zf-C4 1.0 - 1.0 - 1.0 - 1.0 AA0 1.0 MGYG000002494_01908 1.0 methylenetetrahydrofolate reductase [NAD(P)H]. | DNA helicase. MTHFR. A flavoprotein (FAD).-!-The enzyme catalyzes the reversible conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, playing an important role in folate metabolism by regulating the distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis.-!-This enzyme, characterized from Protozoan parasites of the genus Leishmania, is unique among similar characterized eukaryotic enzymes in that it lacks the C-terminal allosteric regulatory domain (allowing it to catalyze a reversible reaction) and uses NADH and NADPH with equal efficiency under physiological conditions. cf. EC 1.5.1.53, EC 1.5.1.54, and EC 1.5.7.1.-!-Formerly EC 1.1.1.68, EC 1.1.1.171, EC 1.1.99.15 and EC 1.7.99.5. | DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA.-!-Some of them unwind duplex DNA with a 3' to 5' polarity, other show 5' to 3' polarity or unwind DNA in both directions.-!-Some helicases unwind DNA as well as RNA.-!-May be identical with EC 3.6.4.13. (1) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH. (2) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH. | ATP + H2O = ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Antifolate resistance|Homologous recombination|Fanconi anemia pathway 1.0 K00297:metF, MTHFR; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]|K10901:BLM, RECQL3, SGS1; bloom syndrome protein [EC:5.6.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 773241 1165052 1166439 0 0 1769198 0 0 677820 1030176 0 0 0 0 0 0 1366071 0 0 0 0 0 0 1875527 0 721648 0 0 1643524 0 0 0 1337991 0 0 0 706757 806767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)SNVIVKDNESLDSALR MGYG000001065_00121;MGYG000001954_00183;MGYG000001531_02509;MGYG000000087_00069;MGYG000001606_01557;MGYG000000255_00059;MGYG000002417_00179;MGYG000002445_00245 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 0.875 203691|Spirochaetes 0.875 L 0.875 PFAM Integrase core domain 0.875 - 0.875 - 1.0 - 1.0 ko:K07497 0.875 - 0.875 - 0.875 - 1.0 - 1.0 ko00000 0.875 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 0.875 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001065_00121 0.125 - - - - 1.0 1.0 1.0 1.0 - 0.875 K07497:K07497; putative transposase 0.875 none 1.0 0 0 590521 747026 579955 641708 472596 988508 807665 1052460 0 639235 534586 841685 660536 0 670218 0 793839 865206 568843 587031 0 738179 460105 792068 862263 0 1045333 717011 477151 510722 491040 732702 0 780570 514790 479275 812064 0 636558 1205948 591711 673546 719313 822081 814418 1417605 0 826180 1207445 981899 1035594 0 908762 0 811786 810015 705278 774416 0 610093 1138759 743359 1071319 0 1230096 797721 549448 915813 751293 964786 0 835342 752689 485081 488715 0 469879 904358 463982 473961 679803 426738 647618 420853 0 369179 294906 700618 541305 0 372099 0 419068 569880 539103 547650 0 541560 0 850615 336298 0 647869 468523 360735 308985 437860 474500 0 619355 347211 490797 378233 0 454170 358258 299031 600554 505252 529019 280561 637352 0 450888 358203 379452 527207 0 304802 0 537907 382375 632412 408390 0 464401 509346 407107 470279 0 227233 340168 411815 423090 571794 566185 0 453738 340881 308884 1220823 0 740933 1293594 784510 641336 551764 730558 1083590 1082485 0 808664 587978 1623973 1022518 0 1264827 0 871719 1570291 790081 459446 0 900174 743999 1359953 1175544 0 1564029 1118301 850653 345198 731963 1122752 0 1327606 1519141 1016076 +(Acetyl)SNVIVKDNESLDSALRR MGYG000001065_00121;MGYG000001954_00183;MGYG000001531_02509;MGYG000000087_00069;MGYG000000278_03375;MGYG000001606_01557;MGYG000000255_00059;MGYG000002417_00179;MGYG000002445_00245 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 0.7777777777777778 203691|Spirochaetes 0.7777777777777778 L 0.7777777777777778 PFAM Integrase core domain 0.7777777777777778 - 0.7777777777777778 - 1.0 - 1.0 ko:K07497 0.7777777777777778 - 0.7777777777777778 - 0.7777777777777778 - 1.0 - 1.0 ko00000 0.7777777777777778 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001065_00121 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 0.7777777777777778 K07497:K07497; putative transposase 0.7777777777777778 none 1.0 1337457 0 776717 0 675746 825261 745227 1087247 936550 1293068 786595 983458 705143 954305 724235 746583 948367 0 945852 1116136 996112 852502 0 838427 757849 1162540 1142027 0 984163 860250 665467 687098 641573 935547 0 211680 809674 598432 1497256 0 1189091 0 1130796 1521819 1413128 1534747 1276109 2768237 1568022 1138740 1893642 1997091 1766110 1938635 2055030 0 1241127 1455480 1670390 1362861 0 1131936 1653020 1532632 1753409 0 2287552 1192692 1098910 1468337 1232037 1947519 0 1788643 1695489 1004700 870404 0 716870 835558 684992 642699 516886 822017 804864 675736 617332 837503 715437 998852 658659 813773 570366 0 514933 828450 785914 0 0 656917 443964 842610 707849 0 1408409 859486 614722 509870 443077 774249 0 787678 642357 768589 799581 0 861580 887904 525226 1003516 658076 1047013 875074 1005882 644872 1017170 566580 795939 1034152 542094 766485 0 719573 551559 736916 742075 0 291049 876915 1015083 941387 0 391361 576276 0 755632 959399 1401313 0 1094215 843292 441354 2201590 0 1492020 2709301 0 1504042 1099159 1058467 2228073 2129671 1026388 1707947 939133 1588221 1714862 858147 2137125 0 1484022 1944353 1028179 1290101 0 1608085 1159269 2239339 1333963 0 2291418 1696606 1664944 890755 1200069 1515935 0 1993994 2292709 1584298 +(Acetyl)SNVIVKENESLDSALR MGYG000000187_00800;MGYG000002528_02821;MGYG000000193_00756;MGYG000000078_01046;MGYG000001319_00312;MGYG000003366_01669;MGYG000001543_03644 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 0.8571428571428571 203691|Spirochaetes 0.8571428571428571 L 0.8571428571428571 PFAM Integrase core domain 0.8571428571428571 - 0.8571428571428571 - 1.0 - 1.0 ko:K07497 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 1.0 - 1.0 ko00000 0.8571428571428571 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000187_00800 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 0.8571428571428571 K07497:K07497; putative transposase 0.8571428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1711591 0 0 0 0 1122306 0 0 0 0 1446285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 719214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469351 0 0 0 0 482212 0 0 0 0 520119 0 0 0 0 0 0 0 0 0 0 +(Acetyl)SNVIVKENESLDSALRR MGYG000000187_00800;MGYG000002528_02821;MGYG000000193_00756;MGYG000000078_01046;MGYG000001319_00312;MGYG000003366_01669;MGYG000001543_03644 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 0.8571428571428571 203691|Spirochaetes 0.8571428571428571 L 0.8571428571428571 PFAM Integrase core domain 0.8571428571428571 - 0.8571428571428571 - 1.0 - 1.0 ko:K07497 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 1.0 - 1.0 ko00000 0.8571428571428571 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000187_00800 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 0.8571428571428571 K07497:K07497; putative transposase 0.8571428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1704678 0 0 0 0 1322091 0 0 0 0 1255997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245923 0 0 0 0 201508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418715 0 0 0 0 0 0 0 0 0 268021 0 0 0 0 0 0 0 0 0 0 +(Acetyl)SVELFDVYEGK MGYG000001364_02003;MGYG000001787_00862;MGYG000003693_02480 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,2FNBF@200643|Bacteroidia,4AM0P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Psort location Cytoplasmic, score 1.0 pheT 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 1.0 6.1.1.20 1.0 ko:K01890 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 B3_4,B5,FDX-ACB,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001364_02003 0.3333333333333333 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01890:FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 966621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1861161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)SWAAEHVVGVAK MGYG000000133_01999 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01999 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 560925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)TAVENAAVSQEELDAK MGYG000002469_00869;MGYG000001292_01825 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 Pyruvate formate lyase-like 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bac_luciferase,Fer4_12,Gly_radical,PFL-like,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002469_00869 0.5 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 223790 0 0 0 283395 0 0 170266 401062 0 0 256097 0 0 0 0 0 0 0 477737 0 0 0 0 0 0 0 0 374356 0 0 0 0 381833 398932 0 0 0 848652 0 0 757873 968956 568306 1193032 975809 692165 834139 0 615058 2340823 780856 0 749203 454452 0 0 1075568 0 347387 0 1247572 0 1046485 928721 0 1447405 860505 1212590 874531 0 837282 872836 779990 752546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287933 0 0 0 380313 0 0 0 0 0 0 0 0 0 465138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)TDTTVEAPATPR MGYG000003683_01126;MGYG000003452_00876;MGYG000002395_00362;MGYG000001490_00332;MGYG000000756_00956;MGYG000002469_01757;MGYG000001292_02350;MGYG000000300_01074;MGYG000003383_00183 phylum d__Bacteria|p__Actinobacteriota 1.0 COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CZCA@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits 1.0 rplE 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02931 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L5,Ribosomal_L5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01126 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02931:RP-L5, MRPL5, rplE; large subunit ribosomal protein L5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390180 0 0 0 0 0 656174 0 383377 0 354212 0 0 0 0 0 0 0 0 0 0 0 0 556168 0 0 0 0 824454 0 0 0 0 0 0 0 0 0 703082 0 2199390 0 0 0 500919 661869 942481 0 476714 0 1496447 0 0 0 0 0 0 0 0 553076 0 407559 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252433 0 0 0 0 0 227427 381848 572084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)TNVPADQVDEVLMGC(Carbamidomethyl)VIQAGLGQNVAR MGYG000000262_02231;MGYG000000077_02464 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02231 0.5 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 508471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 301486 0 490411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632592 1602609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877111 0 1357668 0 0 0 0 0 0 0 0 0 0 930061 0 0 0 0 0 0 0 0 0 259551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251810 0 0 0 0 0 0 0 0 0 0 274803 0 0 0 +(Acetyl)VAGNSATDFENIDKAPEER MGYG000000133_02991;MGYG000001141_02439;MGYG000002286_02469 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02991 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1966287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)VAGNSATDFENIDKAPEERER MGYG000000133_02991 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02991 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1530718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)VAGNTATDFANIDKAPEER MGYG000000216_02406;MGYG000002492_00344;MGYG000003013_00349;MGYG000002670_00364 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000216_02406 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 1645030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1315848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1176894 0 0 0 730009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550554 0 0 0 0 0 656457 0 0 0 0 0 0 0 0 659068 0 147303 0 426531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 561733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132492 0 0 0 0 0 0 0 0 157528 0 423428 0 195931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290773 0 0 0 0 0 464930 0 0 0 0 0 0 0 0 0 0 119726 0 +(Acetyl)VAGNTATDFANIDKAPEERER MGYG000000216_02406;MGYG000002492_00344;MGYG000003013_00349;MGYG000002670_00364 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000216_02406 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)VSGNAEVAFDNIDKAPEER MGYG000004558_00415 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__|m__MGYG000004558 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,27I75@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004558_00415 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2961181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)VTMKNTLGGK MGYG000001300_02837 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001300_02837 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2423788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl)VVQHNLTAMNANR MGYG000004271_01770;MGYG000000153_01160;MGYG000000271_01499;MGYG000000404_00502;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01770 0.2 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 367991 0 272381 919621 0 0 521304 452479 370696 586736 0 427589 0 433237 410596 0 696155 0 0 402380 636041 0 0 323482 550983 516848 699506 0 0 574561 0 0 265640 543984 323249 476675 575133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 844244 0 0 0 763561 561155 0 0 350768 0 865428 815533 0 438810 0 0 459291 467589 0 0 0 852779 1035578 590543 0 0 290554 0 0 0 677198 796013 678430 918048 0 1476981 0 868841 644091 0 1098265 1164108 1050347 1730622 1612913 0 1156658 0 1345640 1571420 736800 1359148 0 0 1532958 1360127 744248 0 1475937 2074776 1840622 1182163 0 0 1947639 0 0 917788 1866582 1804981 1761111 2051083 1007187 +(Acetyl)YALADTVSAGEDSITVDGK MGYG000000280_02459;MGYG000004140_01100;MGYG000003335_00316;MGYG000000164_00800;MGYG000002857_01020;MGYG000000140_01181 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 0.3333333333333333 186801|Clostridia 1.0 G 0.8333333333333334 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_02459 0.16666666666666666 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1543874 0 0 0 0 0 0 1407121 994058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1806028 0 0 0 0 0 0 0 503495 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl_2H(3))ADLNNENLEALEK MGYG000000031_02020;MGYG000003869_00786;MGYG000000118_02883;MGYG000000212_02552;MGYG000000140_00392;MGYG000000184_03011;MGYG000000133_00802;MGYG000004733_02867;MGYG000000142_02498;MGYG000000002_01091;MGYG000000142_00761;MGYG000001698_00102;MGYG000001689_00148;MGYG000000171_02356;MGYG000001338_00681;MGYG000000031_00146;MGYG000004735_00336;MGYG000000119_00545;MGYG000000171_00584;MGYG000001698_02021;MGYG000000002_02249;MGYG000000212_01928 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae 0.7272727272727273 186801|Clostridia 1.0 H 0.9545454545454546 Belongs to the formate--tetrahydrofolate ligase family 0.8636363636363636 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_02020 0.045454545454545456 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01938:fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 617421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 590868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl_2H(3))AVIAYEPVWAIGTGK MGYG000002506_03615 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0149@1|root,COG0149@2|Bacteria,1MWK5@1224|Proteobacteria,1RM8I@1236|Gammaproteobacteria,3WZWR@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 GO:0003674,GO:0003824,GO:0004807,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iJN746.PP_4715 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_03615 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Acetyl_2H(3))LEHTVANLDNVAENTQSAESR MGYG000004271_01770 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01770 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 770829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331570 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Amidine)ACVDSGWISADHQVGQTGK MGYG000002794_01438 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp003487665|m__MGYG000002794 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,2N6VH@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_01438 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3055178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Amidine)ATELVQALK MGYG000002492_01475;MGYG000000018_00274;MGYG000000146_00169;MGYG000000031_02583;MGYG000000404_00576;MGYG000004271_01073;MGYG000000271_00472;MGYG000000142_00943;MGYG000000562_00488;MGYG000000187_00852 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia 0.5 186801|Clostridia 1.0 C 1.0 carboxylase 0.5 oadA 0.8 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01475 0.1 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Amidine)AVTDAGWMTADHQVGQTGK MGYG000002040_01719;MGYG000002619_02235;MGYG000002223_00611;MGYG000001255_01110;MGYG000001300_00291;MGYG000002610_00221;MGYG000003166_01338;MGYG000000195_01569;MGYG000003291_01730;MGYG000002651_00003;MGYG000000022_01320;MGYG000002274_00049 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002040_01719 0.08333333333333333 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 1612588 0 0 0 0 0 0 0 0 0 1147756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1742257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Amidine)CVNMVADLWHAPAPK MGYG000002506_00791;MGYG000002323_02099;MGYG000002506_03156;MGYG000002323_00193;MGYG000002507_00543 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,1RNSQ@1236|Gammaproteobacteria,3XMMA@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria 1.0 gadB 1.0 GO:0003674,GO:0003824,GO:0004351,GO:0006873,GO:0006885,GO:0008150,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019725,GO:0030003,GO:0030004,GO:0030641,GO:0042592,GO:0045852,GO:0048878,GO:0050801,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 1.0 4.1.1.15 1.0 ko:K01580 1.0 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 1.0 M00027 1.0 R00261,R00489,R01682,R02466 1.0 RC00299 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECUMN_1333.ECUMN_1747,iUTI89_1310.UTI89_C1707,ic_1306.c1922 1.0 Pyridoxal_deC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00791 0.2 glutamate decarboxylase. L-glutamate 1-carboxy-lyase. The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate. H(+) + L-glutamate = 4-aminobutanoate + CO2. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|beta-Alanine metabolism|Taurine and hypotaurine metabolism|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Quorum sensing|GABAergic synapse|Type I diabetes mellitus 1.0 K01580:E4.1.1.15, gadB, gadA, GAD; glutamate decarboxylase [EC:4.1.1.15] 1.0 none 1.0 0 0 0 0 0 12936015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15317769 0 0 0 0 0 0 0 0 0 0 0 0 23293937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Amidine)EGVDVSITGNSTNPTR MGYG000000013_02686;MGYG000002854_01085;MGYG000004735_00009;MGYG000002802_02025;MGYG000003821_01383;MGYG000000205_02543;MGYG000004762_01356;MGYG000002582_01129;MGYG000002159_02251;MGYG000000233_02118;MGYG000004797_02907;MGYG000000140_00469;MGYG000001346_01121;MGYG000000089_00653;MGYG000001871_01775;MGYG000004733_02764;MGYG000004276_01664;MGYG000000242_02797;MGYG000000273_02192;MGYG000004482_01421;MGYG000003221_02162;MGYG000004604_01207;MGYG000000133_00506;MGYG000000127_05084;MGYG000004699_02799;MGYG000001303_02421;MGYG000001698_03439;MGYG000002528_00119;MGYG000002275_01873;MGYG000000032_06095;MGYG000000036_01924;MGYG000001604_01691;MGYG000004464_00921;MGYG000004140_00114;MGYG000000029_00187;MGYG000001378_03489;MGYG000001615_01983;MGYG000002213_00389;MGYG000000045_01847;MGYG000002281_03938;MGYG000000080_01714;MGYG000000268_00554;MGYG000000433_01203;MGYG000003446_01092;MGYG000003872_00869;MGYG000000223_01510;MGYG000000031_02290;MGYG000000118_02684;MGYG000000028_01055;MGYG000001027_01414;MGYG000000142_02731;MGYG000002974_01622;MGYG000000038_01050;MGYG000000347_00819;MGYG000000263_01515;MGYG000001606_02183;MGYG000004824_01069;MGYG000002455_00321;MGYG000001797_00319;MGYG000002194_01220;MGYG000002444_01680;MGYG000000269_00015;MGYG000002985_01044;MGYG000000781_01514;MGYG000001400_01185;MGYG000004822_01055;MGYG000000212_00326;MGYG000001688_03060;MGYG000000198_05683;MGYG000002025_00960;MGYG000001560_01190;MGYG000000042_01753;MGYG000000196_00899;MGYG000001881_00612;MGYG000001496_01287;MGYG000001423_03082;MGYG000003012_02646;MGYG000002880_00963;MGYG000002148_02635;MGYG000000301_00647;MGYG000003589_01350;MGYG000003922_03053;MGYG000003693_01584;MGYG000000179_04738;MGYG000000378_01853;MGYG000002438_03055;MGYG000001697_00682;MGYG000002530_01285;MGYG000003241_01405;MGYG000000312_02568;MGYG000004185_01308;MGYG000001599_00424;MGYG000003457_01216;MGYG000003819_00577;MGYG000000374_01026;MGYG000001237_02019;MGYG000000989_03267;MGYG000001707_00757;MGYG000001618_01635;MGYG000004869_01776;MGYG000002478_02896;MGYG000001785_00655 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.3235294117647059 186801|Clostridia 0.6470588235294118 S 1.0 Psort location Cytoplasmic, score 8.87 0.37254901960784315 - 0.9117647058823529 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_02686 0.00980392156862745 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 665200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Amidine)SNLDNISENTSSAESR MGYG000001186_01647;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001186_01647 0.5 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1337692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Amidine)TAPAPAK MGYG000003926_00723 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Rikenella|s__Rikenella microfusus|m__MGYG000003926 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,22UXN@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000003926_00723 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8036084 +(Amidine)TGANTANEALGNLYIK MGYG000001789_01122;MGYG000001306_03308 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001789_01122 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2065754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Amidine)TVDGPSM(Oxidation)KDWR MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003697_01698;MGYG000003457_01802;MGYG000000074_00883;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002834_00628;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000001562_00044;MGYG000004464_00783;MGYG000000254_01186;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000002281_04045;MGYG000000043_01774;MGYG000003363_01174;MGYG000004658_00366;MGYG000004822_01148;MGYG000000044_01948;MGYG000004479_00217;MGYG000000815_03106;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000000412_01371;MGYG000001302.1_00095;MGYG000003252_01337;MGYG000003202_00946;MGYG000003681_00790;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000001661_02632;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000002293_01263;MGYG000003155_00741;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000003908_00471;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.47368421052631576 976|Bacteroidetes 0.9649122807017544 G 0.5087719298245614 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.9473684210526315 gap 0.9824561403508771 - 1.0 1.2.1.12 0.9824561403508771 ko:K00134 0.9824561403508771 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9824561403508771 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9824561403508771 R01061 0.9824561403508771 RC00149 0.9824561403508771 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9824561403508771 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 0.9824561403508771 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.017543859649122806 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9824561403508771 0.9824561403508771 0.9824561403508771 0.9824561403508771 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9824561403508771 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9824561403508771 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Ammonia-loss)TQEALGMVETR MGYG000000142_01601;MGYG000000301_01353;MGYG000000212_01002;MGYG000001338_00128;MGYG000003012_02044;MGYG000003821_00240;MGYG000004733_01675;MGYG000000216_00449 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01601 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Arg)DNELIVGALSVKPR MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 0.5 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2328747 917260 0 0 0 0 0 0 0 1253953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2173080 0 0 0 0 0 +(Arg)DYDVFVGK MGYG000000196_00547;MGYG000000701_00629;MGYG000001378_02385;MGYG000000355_01785;MGYG000002418_01004;MGYG000001306_01408;MGYG000002455_03377;MGYG000001313_02488;MGYG000004622_00252;MGYG000003374_01777;MGYG000000696_00589;MGYG000003681_00897;MGYG000000707_00011;MGYG000002293_00147;MGYG000003697_01824;MGYG000002080_02027;MGYG000002478_02960;MGYG000004885_00524;MGYG000004748_00571;MGYG000004757_01533;MGYG000003312_01455;MGYG000001489_02408;MGYG000004629_01633;MGYG000002281_02540;MGYG000004456_02407;MGYG000000243_01228;MGYG000001056_02440;MGYG000003460_01250;MGYG000001630_00344;MGYG000001750_01904;MGYG000002438_01919;MGYG000001346_01043;MGYG000002218_00698;MGYG000000174_02850;MGYG000000354_00668;MGYG000004495_00381;MGYG000001920_01523;MGYG000003353_01151;MGYG000001783_01031;MGYG000000044_01026;MGYG000001789_00306;MGYG000003362_00812;MGYG000003693_01627;MGYG000000222_02598 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 0.4090909090909091 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00547 0.022727272727272728 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3167346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Arg)EEAEEIKK MGYG000000187_02023 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,25WHU@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000187_02023 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1197641 0 0 +(Arg)GIEDALQEAYPDWAVR MGYG000000133_00237;MGYG000000301_01546 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 1.0 186801|Clostridia 1.0 M 1.0 Cobalt chelatase (CbiK) 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00237 0.5 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 74713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1187306 0 0 0 0 0 0 0 0 0 0 0 2160632 0 0 0 0 0 0 957606 0 0 0 0 0 0 0 0 0 0 682486 0 0 0 0 0 0 0 112692 0 0 0 0 0 0 0 0 0 0 0 0 0 172522 0 0 0 0 88768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388074 0 0 0 0 0 456870 0 0 0 0 0 0 905630 0 0 0 0 367585 0 483128 0 0 0 0 316425 0 0 0 0 0 0 0 0 0 0 730015 0 +(Arg)TQEALGMVETR MGYG000000142_01601;MGYG000000301_01353;MGYG000000212_01002;MGYG000001338_00128;MGYG000003012_02044;MGYG000003821_00240;MGYG000004733_01675;MGYG000000216_00449 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01601 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530384 0 408944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1606219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1154324 0 1203031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Arg)VAGNTATDFENIDKAPEER MGYG000002517_00205;MGYG000003425_03741;MGYG000000018_00453;MGYG000002212_00196;MGYG000001602_02247;MGYG000000501_01307;MGYG000001698_04050;MGYG000001619_01314 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 0.375 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00205 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Arg)VINLDKESEPDIYNAIR MGYG000001306_02577;MGYG000000451_00938;MGYG000001657_02023;MGYG000001733_01436;MGYG000001666_00909;MGYG000001763_01029;MGYG000001164_02313;MGYG000000622_01660;MGYG000003022_01459;MGYG000001531_02004;MGYG000001643_01060;MGYG000004740_01746;MGYG000002445_00666;MGYG000000258_01582;MGYG000000133_00275;MGYG000001065_01729;MGYG000001315_01422;MGYG000000251_02509;MGYG000004721_01708;MGYG000002721_02375 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,3WGXZ@541000|Ruminococcaceae 0.3 186801|Clostridia 0.65 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 0.7 4.1.1.49 0.95 ko:K01610 0.95 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 0.95 M00003,M00170 0.95 R00341 0.95 RC00002,RC02741 0.95 ko00000,ko00001,ko00002,ko01000 0.95 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_02577 0.05 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 0.95 0.95 0.95 0.95 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 0.95 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 0.95 none 1.0 0 0 0 77989 0 0 0 0 88411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122992 0 0 70447 0 0 0 77174 0 0 136127 0 0 121263 49973 0 268717 0 0 225087 0 0 0 144308 0 0 0 0 0 0 0 202043 0 0 0 0 0 0 0 0 0 77051 0 0 0 0 0 0 0 0 96496 129854 95501 66111 0 0 0 192324 135749 167233 0 78386 0 0 0 0 0 0 0 79137 0 242002 0 0 0 141633 86219 197384 0 80362 0 0 0 0 82054 0 0 0 134217 0 0 0 0 0 0 0 0 0 0 248921 0 0 0 0 0 0 0 0 0 169328 0 0 0 0 0 93777 0 0 0 0 0 0 93484 0 0 0 169607 567045 690022 580393 719573 0 0 1075939 540256 576784 0 750956 0 0 0 753201 0 0 0 621102 0 916542 0 0 0 585803 423320 873409 0 948763 0 0 0 954813 794424 0 459893 214895 472223 +(Arg)VSQTGATQNAMTVSWTPENK MGYG000004735_01325 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG5492@1|root,COG5492@2|Bacteria,1UINF@1239|Firmicutes,25EP2@186801|Clostridia,4C1TK@830|Butyrivibrio 1.0 186801|Clostridia 1.0 N 1.0 Fibronectin type 3 domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 fn3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_01325 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1268701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(BITC)DNELIVGALSVKPR MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 0.5 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Benzoyl)TAEGALNETHSILQR MGYG000000154_02141;MGYG000003142_01387;MGYG000003142_01386 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,36ED6@31979|Clostridiaceae 0.6666666666666666 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 fliC 0.6666666666666666 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_IN,Flagellin_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000154_02141 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 142714 0 0 0 0 0 0 0 0 0 165141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 672500 0 0 667915 0 0 0 0 0 0 0 0 0 1279848 1173337 0 0 0 0 0 0 0 0 0 0 637252 0 0 0 657191 0 0 0 0 1013196 0 1380391 0 579019 0 0 0 0 0 0 0 0 0 0 0 0 108235 759747 0 0 0 0 0 0 0 0 0 0 137085 0 0 0 393398 0 0 0 0 0 0 108844 0 +(Benzoyl)TCVAFNVTSKEQVIINTWYGGEMK MGYG000003697_01524 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,4AMYK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01524 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Biotin)ENGIGIVDIVENR MGYG000001338_00631;MGYG000000142_01654;MGYG000002528_00148;MGYG000000216_00388 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3XYUF@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 8.87 1.0 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_00631 0.25 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids|Fluid shear stress and atherosclerosis 1.0 K01940:argG, ASS1; argininosuccinate synthase [EC:6.3.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Biotin)EPGALGEPLYLDVVAALK MGYG000001338_02036 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001338_02036 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Biotin)KYVSERGK MGYG000000133_02916;MGYG000000184_02507 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,3Y0A3@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit 1.0 rpsR 1.0 - 1.0 - 1.0 ko:K02963 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S18 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02916 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02963:RP-S18, MRPS18, rpsR; small subunit ribosomal protein S18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Biotin)LEAMKMQNEIMAPADGTISDVR MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_00268 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Biotin)NDLVPVDYMAYMLK MGYG000001546_00360 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes provencensis|m__MGYG000001546 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,22V16@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001546_00360 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4827188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7345106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Biotin)QEGGYTYIFDLNR MGYG000002478_01528 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01528 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Biotin)SAVYSDLAETILPQLR MGYG000002438_01767;MGYG000000138_03130 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG3063@1|root,COG3063@2|Bacteria,4PKG6@976|Bacteroidetes,2G3G2@200643|Bacteroidia,2322F@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 NU 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01767 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 711043 42589709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14067380 0 0 0 0 0 0 21959821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Brij35)SFDSIDNAPEEKER MGYG000000042_01421;MGYG000004756_01173;MGYG000000196_03974;MGYG000002905_00001;MGYG000000138_00665;MGYG000001661_02666;MGYG000000053_00908;MGYG000004006_00433;MGYG000002762_01733;MGYG000000074_01773;MGYG000001789_00154;MGYG000000273_00431;MGYG000000054_03933;MGYG000000236_01807;MGYG000003701_03123;MGYG000000098_02017;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000001503_00139;MGYG000002281_02290;MGYG000004474_01617;MGYG000003546_00955;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000003446_00658;MGYG000001552_00984;MGYG000001346_01533;MGYG000000243_01988;MGYG000000013_02251;MGYG000001562_01075;MGYG000000348_00283;MGYG000003279_00951;MGYG000000414_00662;MGYG000001655_02933;MGYG000000044_01721;MGYG000002418_00753;MGYG000000117_01463;MGYG000000168_03211 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.025 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6142284 0 0 0 7453476 5355460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 349509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1872262 0 0 0 572219 1581238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7781236 0 0 0 3460870 4774993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 849938 0 0 0 1521005 1322341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Brij58)RAALHEFNPMMGHR MGYG000002528_02478 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002528_02478 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)AANPTPDEPFVLGC(Carbamidomethyl)PTGSSPLGMYK MGYG000000098_01118 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides bouchesdurhonensis|m__MGYG000000098 1.0 COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,4AKMP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000098_01118 1.0 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K02564:nagB, GNPDA; glucosamine-6-phosphate deaminase [EC:3.5.99.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 240776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1750294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1682271 +(C+12)DKPFLMPIEDVMTISGR MGYG000001300_00280 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00280 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11073721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)EPFSALAFK MGYG000002528_01099;MGYG000001756_00184;MGYG000000142_00172;MGYG000000251_00063;MGYG000004769_00436;MGYG000000412_01545;MGYG000002494_01997;MGYG000000233_00808;MGYG000000200_01983;MGYG000001688_04230;MGYG000002421_00703;MGYG000000377_01099;MGYG000003022_00736;MGYG000000038_00759;MGYG000002492_00343;MGYG000001507_06244;MGYG000000269_00802;MGYG000001315_01206;MGYG000000173_00404;MGYG000004642_00845;MGYG000000371_01542;MGYG000000127_03983;MGYG000000206_00900 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.34782608695652173 186801|Clostridia 0.6956521739130435 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 0.9130434782608695 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000002528_01099 0.043478260869565216 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113797 0 0 0 0 0 0 0 0 0 0 0 0 136852 0 0 0 782104 0 0 819384 0 1118421 1000545 746521 0 1182095 0 1242987 0 1114727 0 0 0 0 0 935329 0 625067 0 272991 0 649524 0 0 0 0 0 0 0 0 534394 0 980553 0 0 0 0 0 0 286122 0 0 0 227150 0 0 0 403870 0 0 0 0 0 139292 0 367863 0 0 0 350239 0 0 0 0 0 0 0 0 372853 0 0 0 0 0 0 0 0 0 0 224489 0 157007 0 146066 0 236474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281660 0 0 0 0 154928 0 0 266073 210737 0 0 0 0 0 0 0 0 0 0 0 0 0 424895 0 228537 0 163420 0 0 0 0 0 0 0 0 553777 0 218934 0 +(C+12)FTQAGSEVSALIGR MGYG000001780_01558;MGYG000000213_03735;MGYG000000236_04466;MGYG000002040_00953;MGYG000002033_02017;MGYG000001423_01292;MGYG000000146_02637;MGYG000002478_03332;MGYG000002042_00234;MGYG000000184_02765;MGYG000001619_01979;MGYG000000133_01065;MGYG000002517_03146;MGYG000003366_00975 domain d__Bacteria 1.0 COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,2FP0J@200643|Bacteroidia,4AKDD@815|Bacteroidaceae 0.21428571428571427 186801|Clostridia 0.7142857142857143 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 0.6428571428571429 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 MGYG000001780_01558 0.07142857142857142 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02112:ATPF1B, atpD; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)FTQAGSEVSALLGR MGYG000000427_01448;MGYG000000028_00163;MGYG000001469_01126;MGYG000000213_03735;MGYG000003539_00081;MGYG000001306_00933;MGYG000000562_01724;MGYG000000201_01407;MGYG000000701_01560;MGYG000001552_03919;MGYG000002293_00144;MGYG000004039_01687;MGYG000002689_00805;MGYG000000312_01414;MGYG000004785_01194;MGYG000003498_00140;MGYG000001346_00388;MGYG000001635_01643;MGYG000003693_01490;MGYG000002312_02770;MGYG000000281_00461;MGYG000004679_00453;MGYG000000223_02026;MGYG000001027_00128;MGYG000004893_01690;MGYG000001558_00980;MGYG000000707_01777;MGYG000003695_02077;MGYG000002756_03006;MGYG000001697_01966;MGYG000004732_02133;MGYG000002563_01157;MGYG000004735_02328;MGYG000002148_00268;MGYG000003335_00448;MGYG000000187_01497;MGYG000004479_02289;MGYG000001315_02894;MGYG000002149_01760;MGYG000000953_00406;MGYG000004729_01517;MGYG000000196_02094;MGYG000001461_00699;MGYG000004691_00177;MGYG000004899_02408;MGYG000002140_01025;MGYG000000387_00075;MGYG000003694_02221;MGYG000002996_00349;MGYG000000251_00949;MGYG000002072_00153;MGYG000004558_00486;MGYG000000236_04466;MGYG000002545_01157;MGYG000001689_03424;MGYG000004019_00309;MGYG000001423_01292;MGYG000003702_00794;MGYG000004891_02692;MGYG000000098_02154;MGYG000003381_01169;MGYG000000184_02765;MGYG000003201_00717;MGYG000001374_01252;MGYG000000415_01739;MGYG000000138_00270;MGYG000000133_01065;MGYG000001370_01600;MGYG000000356_01025;MGYG000000323_02070;MGYG000001637_00761;MGYG000003367_02409;MGYG000004317_01545;MGYG000002286_00500;MGYG000000200_02339;MGYG000002641_02172;MGYG000004359_00873;MGYG000000690_01023;MGYG000000280_00975;MGYG000000187_00876;MGYG000003221_00065;MGYG000000515_02194;MGYG000001688_00407;MGYG000002478_03332;MGYG000004767_00409;MGYG000000029_01373;MGYG000001460_03542;MGYG000001007_00074;MGYG000003147_00100;MGYG000003984_00638;MGYG000002455_03102;MGYG000000036_00372;MGYG000001787_02529;MGYG000000215_02164;MGYG000000144_02454;MGYG000000174_01227;MGYG000000963_00198;MGYG000004703_00701;MGYG000001835_01143;MGYG000000287_00695;MGYG000000013_03756;MGYG000002360_00370;MGYG000002721_00656;MGYG000003291_01613;MGYG000004884_01676;MGYG000001655_01482;MGYG000003353_00328;MGYG000002245_01405;MGYG000000022_01420;MGYG000001531_01376;MGYG000000974_00540;MGYG000001447_00122;MGYG000000249_02082;MGYG000003921_00620;MGYG000004548_00278;MGYG000000484_00117;MGYG000002596_00246;MGYG000002517_03146;MGYG000003521_01445;MGYG000004828_00155;MGYG000001770_02068;MGYG000000170_00283;MGYG000000077_01276;MGYG000000417_01692;MGYG000004748_02718;MGYG000000204_01994;MGYG000003899_00596;MGYG000002042_00234;MGYG000002274_00866;MGYG000000175_03681;MGYG000000357_00511;MGYG000001420_00622;MGYG000002560_03936;MGYG000004789_00517;MGYG000003460_00897;MGYG000001338_03253;MGYG000002549_01699;MGYG000000146_02637;MGYG000003822_01520;MGYG000004797_02202;MGYG000002492_00116;MGYG000000164_01253;MGYG000001319_01872;MGYG000000042_02500;MGYG000000356_01862;MGYG000000318_00912;MGYG000002370_03742;MGYG000000105_00454;MGYG000000212_01192;MGYG000002421_01632;MGYG000000171_01102;MGYG000000224_02822;MGYG000003219_00228;MGYG000002218_01404;MGYG000003908_02773;MGYG000000076_02190;MGYG000003363_01154;MGYG000002052_00992;MGYG000002651_01644;MGYG000003362_00510;MGYG000002780_01575;MGYG000000226_00744;MGYG000004757_00198;MGYG000001300_02368;MGYG000001337_02728;MGYG000001400_02546;MGYG000003202_00654;MGYG000003701_04546;MGYG000000195_00674;MGYG000004545_00253;MGYG000000242_03210;MGYG000003500_00568;MGYG000002298_03479;MGYG000000044_01379;MGYG000000222_00569;MGYG000002492_02635;MGYG000000152_02848;MGYG000002552_02014;MGYG000000268_02191;MGYG000002528_01017;MGYG000002216_00439;MGYG000001780_01558;MGYG000001378_01045;MGYG000000278_03709;MGYG000004022_00852;MGYG000001065_01646;MGYG000000252_00908;MGYG000002485_02059;MGYG000000154_01956;MGYG000001313_01535;MGYG000001429_00858;MGYG000002131_00369;MGYG000004526_00330;MGYG000002997_01322;MGYG000001543_00548;MGYG000000867_00145;MGYG000002171_00087;MGYG000000245_03609;MGYG000000039_00037;MGYG000000280_00335;MGYG000002040_00953;MGYG000001489_01224;MGYG000002033_02017;MGYG000000119_02239;MGYG000002203_00701;MGYG000000243_00496;MGYG000003697_01827;MGYG000003812_00631;MGYG000004853_00155;MGYG000002275_01953;MGYG000002610_02017;MGYG000004271_01938;MGYG000001793_01261;MGYG000002772_01182;MGYG000003937_00311;MGYG000001345_02851;MGYG000001785_00789;MGYG000003366_00975;MGYG000002272_00435;MGYG000000262_00505;MGYG000003922_02492;MGYG000004431_00647;MGYG000001056_00141;MGYG000001777_00207;MGYG000003351_01481;MGYG000001186_01383;MGYG000000136_01559;MGYG000001619_01979;MGYG000003411_00809;MGYG000002470_03481;MGYG000002036_00388 domain d__Bacteria 1.0 COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,2FP0J@200643|Bacteroidia,4AKDD@815|Bacteroidaceae 0.1645021645021645 186801|Clostridia 0.5584415584415584 C 0.9783549783549783 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 0.9956709956709957 atpD 0.9956709956709957 - 0.5454545454545454 3.6.3.14 0.9826839826839827 ko:K02112 0.9826839826839827 ko00190,ko00195,ko01100,map00190,map00195,map01100 0.9826839826839827 M00157 0.9826839826839827 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 0.9826839826839827 3.A.2.1 0.9826839826839827 - 1.0 - 0.9653679653679653 ATP-synt_ab,ATP-synt_ab_N 0.9956709956709957 - 1.0 - 1.0 - 1.0 GT58 1.0 MGYG000000427_01448 0.004329004329004329 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 0.9826839826839827 0.9826839826839827 0.9826839826839827 0.9826839826839827 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 0.9826839826839827 K02112:ATPF1B, atpD; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] 0.9826839826839827 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 687304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)IFFAAASAADKMR MGYG000000198_05065;MGYG000000179_02579 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,2686V@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_05065 0.5 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)INNLGFIETPYR MGYG000004830_01656;MGYG000000348_00276 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-485 1.0 COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,2FMDI@200643|Bacteroidia,22X4R@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004830_01656 0.5 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03043:rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3624927 0 0 0 0 +(C+12)LTTEQMLPIVDK MGYG000000212_00765 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_00765 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 829435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)MVEAGILDPVKVTR MGYG000000404_00409 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA11774|s__UBA11774 sp003507655|m__MGYG000000404 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000404_00409 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)QTVVFDTDEGPR MGYG000000312_01321 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eisenbergiella|s__Eisenbergiella sp900539715|m__MGYG000000312 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,4BW0W@830|Butyrivibrio 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000312_01321 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)SSLGAVQNR MGYG000002506_01312;MGYG000000489_01309;MGYG000002670_01665;MGYG000002670_01663;MGYG000002492_03078;MGYG000001470_04044 domain d__Bacteria 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6666666666666666 186801|Clostridia 0.6666666666666666 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 0.6666666666666666 - 0.6666666666666666 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_01312 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 329885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3349796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)TATAEQAQEIHAFIR MGYG000004899_00852;MGYG000000243_02890;MGYG000002478_00492 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0149@1|root,COG2259@1|root,COG0149@2|Bacteria,COG2259@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia,4AVCD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 DoxX,MauE,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004899_00852 0.3333333333333333 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1625018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 764583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1471624 0 0 0 0 0 0 1880646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)TLDYDLIITGR MGYG000004285_02086;MGYG000004642_01566 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36EI7@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004285_02086 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 304394 0 408281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306882 0 279022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 678868 0 754580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)VGYVMWPLR MGYG000002279_01699;MGYG000002992_02039 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,27UV0@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) 1.0 gltX 1.0 - 1.0 6.1.1.17,6.1.1.24 1.0 ko:K01885,ko:K09698 1.0 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 1.0 M00121,M00359,M00360 1.0 R03651,R05578 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 1.0 - 1.0 - 1.0 - 1.0 tRNA-synt_1c 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_01699 0.5 glutamate--tRNA ligase. | glutamate--tRNA(Gln) ligase. glutamyl-tRNA synthetase. | nondiscriminating glutamyl-tRNA synthetase. When this enzyme acts on tRNA(Glu), it catalyzes the same reaction as EC 6.1.1.17.-!-It has, however, diminished discrimination, so that it can also form glutamate-tRNA(Gln).-!-This relaxation of specificity has been found to result from the absence of a loop in the tRNA that specifically recognizes the third position of the anticodon.-!-This accounts for the ability of this enzyme in, for example, Bacillus subtilis, to recognize both tRNA1(Gln) (UUG anticodon) and tRNA(Glu) (UUC anticodon) but not tRNA2(Gln) (CUG anticodon).-!-The ability of this enzyme to recognize both tRNA(Glu) and one of the tRNA(Gln) isoacceptors derives from their sharing a major identity element, a hypermodified derivative of U34 (5-methylaminomethyl-2- thiouridine).-!-The glutamyl-tRNA(Gln) is not used in protein synthesis until it is converted by EC 6.3.5.7 into glutaminyl-tRNA(Gln). ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu). | ATP + L-glutamate + tRNA(Glx) = AMP + diphosphate + L-glutamyl-tRNA(Glx). 1.0 1.0 1.0 1.0 Porphyrin metabolism|Aminoacyl-tRNA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01885:EARS, gltX; glutamyl-tRNA synthetase [EC:6.1.1.17]|K09698:gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24] 1.0 none 1.0 0 0 141071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 301226 0 0 0 0 407148 0 0 135311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1338881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1087333 0 0 0 0 1295071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204915 0 0 0 0 204460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)VQSDSSDDTKEK MGYG000000198_05929 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,21ZAM@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_05929 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 5709476 0 0 0 0 1613057 0 0 0 3502592 0 0 0 0 3923359 0 3645316 0 0 0 0 2195139 0 3188264 0 5292322 0 0 0 3714586 0 0 0 0 0 0 4958519 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147037 0 0 0 0 49137 0 0 0 203119 0 0 0 0 240267 0 48207 0 0 0 0 53933 0 93297 0 152200 0 0 0 56266 0 0 0 0 0 0 166537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)WILDNVEGAR MGYG000000157_02893;MGYG000003142_01159;MGYG000003425_03258;MGYG000000268_00688;MGYG000001698_01656;MGYG000003381_02295;MGYG000001326_01728;MGYG000001619_01501;MGYG000000142_00490;MGYG000000164_01754;MGYG000001338_01881;MGYG000002517_00259;MGYG000004785_01998;MGYG000002517_00523;MGYG000001508_01328;MGYG000001470_01135;MGYG000001464_01751;MGYG000000263_01173 domain d__Bacteria 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 0.2222222222222222 186801|Clostridia 0.7777777777777778 C 0.5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 0.7222222222222222 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000157_02893 0.05555555555555555 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5560579 0 0 0 +(C+12)WILDNVEGVR MGYG000000179_02171;MGYG000000198_04024;MGYG000000087_01966 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02171 0.3333333333333333 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 461529 1350017 0 0 0 0 0 0 1401625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309527 0 0 0 0 0 0 127909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1357285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)WLLDNVEGAR MGYG000003142_01159;MGYG000000157_02893;MGYG000000337_00220;MGYG000002807_00504;MGYG000003425_03258;MGYG000000268_00688;MGYG000001698_01656;MGYG000001619_01501;MGYG000000142_00490;MGYG000000389_02030;MGYG000000164_01754;MGYG000000334_01513;MGYG000000083_02973;MGYG000001627_01644;MGYG000001338_01881;MGYG000002517_00259;MGYG000002517_00523;MGYG000001508_01328;MGYG000004431_01182;MGYG000001470_01135;MGYG000001464_01751 domain d__Bacteria 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 0.23809523809523808 186801|Clostridia 0.7619047619047619 C 0.5238095238095238 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 0.9523809523809523 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 0.9523809523809523 FGGY_C,FGGY_N,MazG 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003142_01159 0.047619047619047616 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 322764 0 315422 0 2357008 1081792 236040 273646 0 95439 0 0 0 2717254 0 2663366 398711 0 585063 625884 2729319 759150 0 313590 0 255261 0 0 0 0 0 0 226639 286658 304727 184475 326760 220157 0 0 108571 0 139866 0 138604 219488 0 99638 0 0 0 75854 0 0 0 0 104259 236423 0 0 0 0 0 112257 0 0 0 0 219372 0 88719 0 230499 99112 0 0 160786 0 0 0 78942 0 220582 276922 0 273164 0 0 0 118939 229382 180467 100607 0 270410 279704 0 141586 0 181767 0 181440 0 0 0 0 155905 0 123992 334312 344235 243253 366664 0 507655 0 240473 0 404336 294051 514983 0 0 351258 0 0 0 1296254 1514248 645817 811762 0 1117380 1596873 1020706 128039 0 0 0 1760539 0 0 0 0 484020 0 491220 1549478 1990940 1855297 0 669116 707456 0 710707 0 646732 1040576 1896387 1309801 0 1998137 0 0 0 257365 2338720 1189438 3000089 0 2370551 2210501 1983397 2049295 0 191994 0 3274428 0 0 0 0 2495137 0 3366766 5696661 0 0 5822232 0 +(C+12)WLLDNVPGAR MGYG000001315_01111;MGYG000004733_00600;MGYG000003152_00994;MGYG000002641_02439;MGYG000000003_00783;MGYG000000038_01493;MGYG000000489_01562;MGYG000001749_00513;MGYG000002312_03080;MGYG000000245_01078;MGYG000003374_00008;MGYG000002926_00484;MGYG000003166_01103;MGYG000001546_02385;MGYG000002274_01022;MGYG000004536_01113;MGYG000002802_02075;MGYG000000195_02804;MGYG000002279_02521;MGYG000000205_00108;MGYG000000252_02425;MGYG000004525_02134;MGYG000004762_00048 domain d__Bacteria 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,27V84@189330|Dorea 0.30434782608695654 186801|Clostridia 0.782608695652174 H 0.43478260869565216 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 0.5652173913043478 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01111 0.043478260869565216 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1176119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C+12)WLPIAAAAQLTK MGYG000000301_01129;MGYG000000133_00992 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0510@1|root,COG0510@2|Bacteria,1TQW6@1239|Firmicutes,248A0@186801|Clostridia,36UHB@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 M 1.0 Phosphotransferase enzyme family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 APH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_01129 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5354316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C8-QAT)DFDDAVEQAVWLEHGNR MGYG000000201_01080;MGYG000001338_00133;MGYG000002772_00609;MGYG000000133_00166;MGYG000004733_01680;MGYG000002298_02774;MGYG000000268_01901;MGYG000000175_02146;MGYG000000142_01606;MGYG000000212_01007;MGYG000002298_00039;MGYG000000249_01486 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,3XZI5@572511|Blautia 0.5833333333333334 186801|Clostridia 1.0 C 1.0 Aldehyde dehydrogenase family 0.8333333333333334 eutE 1.0 - 1.0 1.2.1.10,1.2.1.87 1.0 ko:K00132,ko:K13922 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00228,R01172,R09097 1.0 RC00004,RC00184,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_01080 0.08333333333333333 acetaldehyde dehydrogenase (acetylating). | propanal dehydrogenase (CoA-propanoylating). aldehyde dehydrogenase (acylating). Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme forms a bifunctional complex with EC 4.1.3.43, with a tight channel connecting the two subunits.-!-Also acts, more slowly, on glycolaldehyde and butanal.-!-In Pseudomonas species the enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.10.-!-NADP(+) can replace NAD(+) with a much slower rate. acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NAD(+) + propanal = H(+) + NADH + propanoyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00132:E1.2.1.10; acetaldehyde dehydrogenase (acetylating) [EC:1.2.1.10]|K13922:pduP; propionaldehyde dehydrogenase [EC:1.2.1.87] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340289 0 0 0 0 0 0 0 0 0 0 813698 0 581420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762885 0 0 0 0 0 0 0 0 0 0 952806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 935172 0 0 0 0 0 0 0 0 0 0 700242 0 548089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 653037 0 0 0 0 0 0 0 0 0 0 385724 0 795021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1163783 0 0 0 0 0 0 0 0 0 0 261023 0 +(C8-QAT)LAAYGAELVLTEGAK MGYG000002517_02918 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the cysteine synthase cystathionine beta- synthase family 1.0 cysK 1.0 - 1.0 2.5.1.47 1.0 ko:K01738 1.0 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00021 1.0 R00897,R03601,R04859 1.0 RC00020,RC02814,RC02821 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PALP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02918 1.0 cysteine synthase. OAS sulfhydrylase. Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors.-!-Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53.-!-Formerly EC 4.2.99.8. hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Sulfur metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01738:cysK; cysteine synthase [EC:2.5.1.47] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(C8-QAT)MSNISAYDQGLNESFQGAFK MGYG000003891_02475 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_02475 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(CAF)FDFRGVEATFELNDANK MGYG000002494_00458 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,3XN7B@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 UPF0234 protein YajQ 1.0 yajQ 1.0 GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 - 1.0 ko:K09767 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF520 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00458 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K09767:yajQ; cyclic-di-GMP-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 512708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 777231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(CAF)IQAGSEVSALLGR MGYG000004769_01910 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4H2IA@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 - 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 MGYG000004769_01910 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02112:ATPF1B, atpD; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(CAF)RTAVQQEINQLASEITR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00135 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(CAMthiopropanoyl)YAIIATGGK MGYG000002517_01481;MGYG000000077_02303;MGYG000000171_00402;MGYG000000271_00118;MGYG000000028_00974;MGYG000004087_00797;MGYG000001714_01831;MGYG000000179_02644;MGYG000000198_03199;MGYG000001531_02377;MGYG000003684_00524 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,269QB@186813|unclassified Clostridiales 0.36363636363636365 186801|Clostridia 1.0 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 - 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01481 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02888:RP-L21, MRPL21, rplU; large subunit ribosomal protein L21 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133976 0 0 0 0 0 0 0 0 0 0 0 0 +(CLIP_TRAQ_2)GMSVLEYFIASHGAR MGYG000000215_00573;MGYG000002080_00535 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000000215_00573 0.5 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4860935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(CLIP_TRAQ_2)ITELGIYPAVDPLESTSR MGYG000001315_02894;MGYG000003367_02409;MGYG000000243_00496;MGYG000002478_03332;MGYG000000236_04466;MGYG000000415_01739;MGYG000004748_02718;MGYG000004797_02202;MGYG000003363_01154;MGYG000000044_01379;MGYG000003521_01445 domain d__Bacteria 1.0 COG0055@1|root,COG0055@2|Bacteria,4NF1Q@976|Bacteroidetes,2FP0J@200643|Bacteroidia,4AKDD@815|Bacteroidaceae 0.6363636363636364 976|Bacteroidetes 0.9090909090909091 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 - 0.9090909090909091 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 MGYG000001315_02894 0.09090909090909091 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02112:ATPF1B, atpD; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(CLIP_TRAQ_3)IAMHTLDGGR MGYG000000076_01275;MGYG000000217_01340;MGYG000004740_00273;MGYG000001615_04301;MGYG000000205_02133;MGYG000000164_00686;MGYG000003074_00587;MGYG000000153_01461;MGYG000001637_02229;MGYG000000255_01556;MGYG000001315_01868;MGYG000001617_02045;MGYG000000489_01025;MGYG000002670_01509;MGYG000002492_00659;MGYG000002528_02667;MGYG000000077_02467;MGYG000000204_00801;MGYG000003694_00879;MGYG000001777_01058;MGYG000002278_01893;MGYG000000312_02425;MGYG000000127_04022;MGYG000001793_01807;MGYG000000280_01471;MGYG000002945_00737;MGYG000000139_01931;MGYG000001564_00904;MGYG000000136_00900;MGYG000000271_02102;MGYG000000404_01797;MGYG000004271_00233;MGYG000000389_02149;MGYG000004039_00586;MGYG000001814_02502;MGYG000004762_01001;MGYG000001186_01721;MGYG000001199_01107;MGYG000000028_00943;MGYG000002517_00542;MGYG000000262_02234;MGYG000003486_02522;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.37209302325581395 186801|Clostridia 1.0 C 0.6976744186046512 acyl-CoA dehydrogenase 0.3953488372093023 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000076_01275 0.023255813953488372 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(CLIP_TRAQ_3)VIEFNPALEENNRYVEIMDIVK MGYG000002492_00661 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00661 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603538 0 0 0 0 677662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12179258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1642995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AAATAIYGSR MGYG000004748_03723;MGYG000001789_02910;MGYG000001925_00084 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG4206@1|root,COG1629@2|Bacteria,COG4206@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004748_03723 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2042534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1162985 0 0 0 0 0 +(Carbamidomethyl)AAAVNIVPNSTGAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_02459 0.011111111111111112 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AADDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 342686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375111 316750 0 0 667383 0 0 0 466068 160542 332195 365372 0 301807 0 0 0 0 0 0 0 0 0 0 0 0 1140561 0 0 0 0 0 0 0 0 0 0 0 0 315677 0 0 276065 0 0 0 396305 232859 899485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1751417 0 0 0 0 0 0 3526729 0 0 0 0 0 2056657 2726339 0 0 0 0 0 0 0 0 0 0 2273330 1939803 0 0 1712148 0 0 0 2748220 2088357 1799099 2882425 0 829638 0 0 0 0 0 0 722023 0 0 0 0 0 0 312605 0 0 0 0 0 0 0 0 0 0 1095563 459680 0 0 1283294 0 0 0 905318 498841 750079 1653724 0 +(Carbamidomethyl)AAIEEGIVPGGGVAYIR MGYG000004876_02137;MGYG000002478_00380;MGYG000003363_02977;MGYG000002171_01748;MGYG000004763_01826;MGYG000002470_00024;MGYG000000243_00634;MGYG000002455_00111;MGYG000001346_02504;MGYG000002933_01569 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004876_02137 0.1 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AALEEAGASVELK MGYG000003730_01040 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium vaginale_E|m__MGYG000003730 1.0 COG0222@1|root,COG0222@2|Bacteria,2IKNW@201174|Actinobacteria,4D0W2@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003730_01040 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2378388 2768829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2691950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AASGNIIPSSTGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.018867924528301886 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9811320754716981 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)ADDAAGLAISEK MGYG000002934_00200 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Caproiciproducens|s__Caproiciproducens sp900546895|m__MGYG000002934 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 hag 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002934_00200 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1531635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AGDDAAGLTISEK MGYG000000356_01643;MGYG000000484_02079;MGYG000000153_01160;MGYG000000389_01367;MGYG000000076_03207;MGYG000001186_01647 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000356_01643 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AGIALTDTFVK MGYG000003589_01892;MGYG000002540_02142;MGYG000001783_01519;MGYG000003457_01802;MGYG000002057_00658;MGYG000004006_01717;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000002944_01470;MGYG000001345_01069;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002006_01638;MGYG000001749_01249;MGYG000002455_02200;MGYG000001356_02656;MGYG000004487_00117;MGYG000001546_00360;MGYG000000086_02423;MGYG000004726_03349;MGYG000004638_00838;MGYG000000377_02142;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000003681_00790;MGYG000000003_00712;MGYG000002933_02039;MGYG000004482_00387;MGYG000000196_00479;MGYG000003693_00860;MGYG000001661_02632;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000002867_00573;MGYG000000053_01377;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.43859649122807015 976|Bacteroidetes 0.6666666666666666 C 0.5614035087719298 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7719298245614035 gap 0.9473684210526315 - 1.0 1.2.1.12 0.9649122807017544 ko:K00134 0.9649122807017544 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9649122807017544 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9649122807017544 R01061 0.9649122807017544 RC00149 0.9649122807017544 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9649122807017544 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 0.9649122807017544 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003589_01892 0.017543859649122806 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9649122807017544 0.9649122807017544 0.9649122807017544 0.9649122807017544 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9649122807017544 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9649122807017544 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545358 0 0 0 0 0 0 0 0 0 733097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AGIQLSPR MGYG000000170_00182 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900240235|m__MGYG000000170 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,22V16@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000170_00182 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1409206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AGIQQEIR MGYG000000152_00117;MGYG000000141_00660;MGYG000002580_01017;MGYG000000095_00173;MGYG000000501_01598;MGYG000000255_00059;MGYG000004055_00346;MGYG000004431_01868;MGYG000000245_00531;MGYG000000280_00278;MGYG000002445_00245;MGYG000003425_03997;MGYG000002492_01669;MGYG000004414_01258;MGYG000000252_02525;MGYG000002992_00107;MGYG000002417_00179;MGYG000002836_01191;MGYG000002289_01189;MGYG000000187_00800;MGYG000002528_02821;MGYG000004250_00815;MGYG000000515_01072;MGYG000003500_01059;MGYG000001439_01091;MGYG000004785_00784;MGYG000000997_01904;MGYG000000359_00890;MGYG000000274_02713;MGYG000000175_00584;MGYG000002945_00316;MGYG000001619_00224;MGYG000000076_00705;MGYG000000398_02117;MGYG000001637_00450;MGYG000000067_02614;MGYG000004891_00983;MGYG000004799_00190;MGYG000002393_01989;MGYG000004879_00968;MGYG000000242_01546;MGYG000001065_00121;MGYG000004691_01413;MGYG000002304_00585;MGYG000004548_02161;MGYG000002278_00495;MGYG000001954_00183;MGYG000000312_02314;MGYG000001456.1_00409;MGYG000000136_01431;MGYG000000562_00584;MGYG000000204_01228;MGYG000000159_01824;MGYG000002286_00159;MGYG000000909_01150;MGYG000003694_00392;MGYG000004519_00667;MGYG000000193_00756;MGYG000000078_01046;MGYG000000231_00737;MGYG000003366_01669;MGYG000001543_03644;MGYG000001571_02035;MGYG000000087_00069;MGYG000004740_00388;MGYG000001193_00159;MGYG000000229_01952;MGYG000002247_01714;MGYG000002517_01319;MGYG000000325_01546;MGYG000003381_02022;MGYG000004039_02066;MGYG000000145_01503;MGYG000001531_02509;MGYG000000154_00852;MGYG000000278_03375;MGYG000001606_01557;MGYG000002963_01774;MGYG000001814_01719;MGYG000000217_00552;MGYG000001319_00312 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 0.9259259259259259 203691|Spirochaetes 0.9259259259259259 L 0.9259259259259259 PFAM Integrase core domain 0.9259259259259259 - 0.9259259259259259 - 1.0 - 1.0 ko:K07497 0.9259259259259259 - 0.9259259259259259 - 0.9259259259259259 - 1.0 - 1.0 ko00000 0.9259259259259259 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 0.9259259259259259 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000152_00117 0.012345679012345678 - - - - 1.0 1.0 1.0 1.0 - 0.9259259259259259 K07497:K07497; putative transposase 0.9259259259259259 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AGPVILEPIMK MGYG000000358_00904 genome d__Bacteria|p__Elusimicrobiota|c__Elusimicrobia|o__Elusimicrobiales|f__Elusimicrobiaceae|g__UBA1436|s__UBA1436 sp002329395|m__MGYG000000358 1.0 COG0480@1|root,COG0480@2|Bacteria 1.0 2|Bacteria 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000000358_00904 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AGTTAESLAK MGYG000004271_00231;MGYG000000245_02019;MGYG000000271_02104 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00231 0.3333333333333333 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AGVKPEMVDEVK MGYG000004271_00231;MGYG000000489_01023;MGYG000000271_02104;MGYG000000280_01473;MGYG000001637_02269;MGYG000003694_00877 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00231 0.16666666666666666 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 3132296 1898042 0 0 0 2858956 0 0 0 1997980 0 0 0 0 2860622 0 0 0 0 0 0 0 0 0 0 3024464 0 0 0 0 0 0 0 0 0 3463999 0 0 0 181822 0 0 0 177804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174488 0 0 0 0 0 0 0 0 0 354597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189173 0 0 0 0 0 0 0 0 0 154991 0 0 0 0 0 0 0 0 0 0 80328 0 +(Carbamidomethyl)AGVTKEDINAAMK MGYG000003694_01737;MGYG000001311_02933;MGYG000001186_01925;MGYG000001065_01088;MGYG000000271_03250;MGYG000004271_00554;MGYG000000404_00344;MGYG000001493_05257;MGYG000002517_01026;MGYG000000179_02084;MGYG000002492_01379;MGYG000000489_00503;MGYG000000198_04065 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6153846153846154 186801|Clostridia 1.0 G 0.6153846153846154 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.6153846153846154 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AKFVTIGER MGYG000004785_01065;MGYG000000142_02501;MGYG000002298_01759;MGYG000000171_00587;MGYG000002286_00195;MGYG000000251_00652;MGYG000000200_00066;MGYG000002312_01594;MGYG000000002_02252;MGYG000000141_00320;MGYG000000252_00281;MGYG000003821_01555;MGYG000000216_02769;MGYG000004296_01202;MGYG000002966_01692;MGYG000001338_02424;MGYG000002186_02647;MGYG000000184_00686;MGYG000001602_02146;MGYG000000050_00432;MGYG000001027_02054;MGYG000000213_00152 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3XZQ5@572511|Blautia 0.6818181818181818 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 8.87 0.6818181818181818 acsE 1.0 - 1.0 2.1.1.258 1.0 ko:K15023 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R02289,R10243 1.0 RC00004,RC00113,RC01144,RC02871,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pterin_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004785_01065 0.045454545454545456 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the N(5) group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein.-!-Involved, together with EC 1.2.7.4 and EC 2.3.1.169, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea. (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein] = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K15023:acsE; 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)ALNDLAAIK MGYG000000301_01012;MGYG000002528_00367;MGYG000004785_01017;MGYG000000002_02120;MGYG000003012_02911;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000001338_02547;MGYG000000133_02283;MGYG000003335_00316;MGYG000000213_00374;MGYG000000806_01930 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.9230769230769231 186801|Clostridia 1.0 C 0.9230769230769231 Psort location Cytoplasmic, score 0.9230769230769231 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_01012 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1348870 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AQAHIDAGAK MGYG000002999_00356;MGYG000002540_02142;MGYG000000375_01483;MGYG000001311_02933;MGYG000003012_02911;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000000205_02269;MGYG000003695_01114;MGYG000000145_03615;MGYG000002445_01920;MGYG000000193_03247;MGYG000002944_01470;MGYG000003110_00098;MGYG000004809_00788;MGYG000004799_00704;MGYG000000002_02120;MGYG000001065_01088;MGYG000002946_02881;MGYG000002966_00075;MGYG000002131_02428;MGYG000000242_02076;MGYG000003335_00316;MGYG000000233_00345;MGYG000001577_01888;MGYG000000099_02094;MGYG000003702_00925;MGYG000000252_01324;MGYG000000365_00999;MGYG000000301_01012;MGYG000004087_02290;MGYG000000312_01508;MGYG000001688_03910;MGYG000002972_00451;MGYG000000423_01499;MGYG000002857_01020;MGYG000002212_00259;MGYG000004296_01958;MGYG000000213_00374;MGYG000000281_02732;MGYG000000179_02084;MGYG000000142_01979;MGYG000000263_01341;MGYG000002095_00148;MGYG000004411_00321;MGYG000000806_01930;MGYG000001505_01467;MGYG000000212_01474;MGYG000001661_02632;MGYG000004785_01017;MGYG000000171_00850;MGYG000001757_00726;MGYG000001338_02547;MGYG000001602_01805;MGYG000003074_01265;MGYG000000133_02283;MGYG000002298_02410;MGYG000004246_01300;MGYG000001315_01699;MGYG000002035_01208 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.47540983606557374 186801|Clostridia 0.8852459016393442 C 0.7704918032786885 Psort location Cytoplasmic, score 0.47540983606557374 gap 0.9672131147540983 - 0.9672131147540983 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002999_00356 0.01639344262295082 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AQAHIEAGAK MGYG000000044_01948;MGYG000003312_01022;MGYG000003831_00170;MGYG000002455_02200;MGYG000003542_01626;MGYG000000354_00611;MGYG000002556_00846;MGYG000004748_00450;MGYG000003202_00946;MGYG000001345_01069;MGYG000003681_00790;MGYG000000196_00479;MGYG000001643_00773;MGYG000004464_00783;MGYG000002478_03999;MGYG000001313_02393;MGYG000002549_00455;MGYG000002737_00455;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000003469_01436;MGYG000001493_05257;MGYG000002281_04045;MGYG000000673_01725;MGYG000002905_02083;MGYG000000198_04065;MGYG000000941_01985 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.7857142857142857 976|Bacteroidetes 0.9285714285714286 C 0.8571428571428571 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.9285714285714286 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000044_01948 0.03571428571428571 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 314981 0 0 0 0 177000 0 0 0 0 0 0 0 0 0 159544 0 0 0 0 557539 0 0 0 0 421413 0 0 0 0 461796 0 0 0 0 316903 0 0 218364 0 0 0 0 760936 0 0 0 0 0 0 0 0 0 259186 0 0 0 0 459205 0 0 0 0 681146 0 0 0 0 186192 0 0 0 0 87005 0 0 281928 0 0 0 0 407205 0 0 0 0 0 0 0 0 0 176777 0 0 0 0 423335 0 0 0 0 407877 0 0 0 0 161232 0 0 0 0 200609 0 0 64890 0 0 0 0 177195 0 0 0 0 0 0 0 0 0 147306 0 0 0 0 0 0 0 0 0 81049 0 0 0 0 68771 0 0 0 0 250624 0 0 192213 0 0 0 0 85927 0 0 0 0 0 0 0 0 0 373567 0 0 0 0 482029 0 0 0 0 154068 0 0 0 0 0 0 0 0 0 138812 +(Carbamidomethyl)AQAHINAGAR MGYG000000251_00555;MGYG000000280_02459;MGYG000003694_01737;MGYG000002974_01418;MGYG000004140_01100;MGYG000001186_01925;MGYG000000484_01691;MGYG000000398_00286;MGYG000001683_01827;MGYG000001748_01525;MGYG000000271_03250;MGYG000004271_00554;MGYG000001319_00348;MGYG000003828_01578;MGYG000000404_00344;MGYG000002517_01026;MGYG000000153_00303;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000140_01181 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.8095238095238095 186801|Clostridia 1.0 G 0.9047619047619048 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8095238095238095 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_00555 0.047619047619047616 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 182637 0 0 0 0 0 192433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 51950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371759 0 0 0 0 0 342681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 764970 0 0 0 0 0 707797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 85890 0 0 0 0 0 111592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AQIGVTTSEYDKEK MGYG000002156_00861 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550585|m__MGYG000002156 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2N6RJ@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002156_00861 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1002351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)ASVPFFK MGYG000004271_02656;MGYG000003215_00001;MGYG000000280_01601;MGYG000000271_02750;MGYG000000404_01534;MGYG000002517_02338;MGYG000000154_01456;MGYG000000076_01479 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,3NGQJ@46205|Pseudobutyrivibrio 0.875 186801|Clostridia 1.0 I 1.0 Enoyl-CoA hydratase/isomerase 0.875 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_02656 0.125 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)AWAAEHVVGVAK MGYG000000201_02350;MGYG000001310_02359 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 0.5 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 0.5 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_02350 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)DAGYLTR MGYG000001666_00329;MGYG000004797_04274;MGYG000000074_01764;MGYG000000358_00901;MGYG000000196_03983;MGYG000001630_01150;MGYG000004763_01698;MGYG000001489_05036;MGYG000001346_01525;MGYG000002438_02330;MGYG000002478_00805 domain d__Bacteria 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 0.45454545454545453 976|Bacteroidetes 0.9090909090909091 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 0.9090909090909091 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 0.9090909090909091 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000001666_00329 0.09090909090909091 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1547397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)DELGIKGAFTSAGMDGSSDWR MGYG000002298_00512;MGYG000004733_01177 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3XZHY@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 GH49 1.0 MGYG000002298_00512 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2778665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)DIHIIDLQK MGYG000003504_00560 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-314|g__CAG-1435|s__CAG-1435 sp003537755|m__MGYG000003504 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,267MF@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003504_00560 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2496064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5130945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)DKLVEAIR MGYG000000179_02087;MGYG000004464_00924 domain d__Bacteria 1.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,267NF@186813|unclassified Clostridiales 0.5 186801|Clostridia 0.5 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 - 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Metalloenzyme,PglZ,Phosphodiest,iPGM_N 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02087 0.5 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K15633:gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1268507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)EAILADAQAK MGYG000004719_01421;MGYG000002492_01520;MGYG000000271_00139;MGYG000004271_00266;MGYG000000489_00322;MGYG000002517_01451 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 C 0.8333333333333334 Psort location Cytoplasmic, score 0.8333333333333334 - 0.8333333333333334 - 1.0 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 GARP,HrpE 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004719_01421 0.16666666666666666 - - - - 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4207544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)EAINDAMK MGYG000003702_00925 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eisenbergiella|s__Eisenbergiella sp900066775|m__MGYG000003702 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003702_00925 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2854094 0 0 0 0 3262647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)EKAQAHIEAGAK MGYG000000044_01948;MGYG000001643_00773;MGYG000004464_00783;MGYG000003831_00170;MGYG000002478_03999;MGYG000000243_01331;MGYG000000273_02725;MGYG000000354_00611;MGYG000003469_01436;MGYG000000673_01725;MGYG000002556_00846;MGYG000003202_00946;MGYG000003681_00790;MGYG000002905_02083;MGYG000000941_01985 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.7333333333333333 976|Bacteroidetes 1.0 C 0.7333333333333333 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000044_01948 0.06666666666666667 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)ELKNGGKIQLVGFGTFEVSER MGYG000001338_00344 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3Y0HQ@572511|Blautia 1.0 186801|Clostridia 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hup 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_00344 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2110426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)ELLSEYDFPGDDTPIIR MGYG000003166_01350;MGYG000000022_02283;MGYG000002040_01212;MGYG000002272_01482;MGYG000002619_00483;MGYG000001300_00280;MGYG000002641_00069 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_01350 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)FGLADAGNIYGR MGYG000001300_02567;MGYG000001642_00033;MGYG000000280_02177;MGYG000000185_00279;MGYG000002978_00618;MGYG000002651_00281;MGYG000004087_02957;MGYG000002279_01466;MGYG000003486_01767;MGYG000004733_02577;MGYG000002298_00566;MGYG000002274_02337;MGYG000000252_02565;MGYG000000090_02004;MGYG000003266_00234;MGYG000000028_02056;MGYG000001315_02833;MGYG000002775_00932;MGYG000003361_00996;MGYG000000142_03199;MGYG000004740_00564;MGYG000001502_02222;MGYG000002445_01002;MGYG000000383_00104;MGYG000002040_00064;MGYG000001086_01260;MGYG000001567_00737;MGYG000001737_00599;MGYG000004519_00910;MGYG000000693_01345;MGYG000000212_00356;MGYG000000213_02746;MGYG000002272_02328;MGYG000000031_03298;MGYG000004681_00802;MGYG000002528_02771;MGYG000000195_01901;MGYG000000146_02288;MGYG000001456.1_01574;MGYG000000171_00165;MGYG000001338_01027;MGYG000000100_00277;MGYG000001303_02138;MGYG000002545_01885;MGYG000000291_00793;MGYG000000269_00514;MGYG000001636_01145;MGYG000000216_02897;MGYG000000038_00531;MGYG000002641_02488;MGYG000002050_00805;MGYG000002312_02592;MGYG000000140_01570;MGYG000002992_00682;MGYG000002065_00609;MGYG000003291_00536;MGYG000004679_00587;MGYG000000022_02103;MGYG000001645_01495;MGYG000003891_00287;MGYG000000164_02014;MGYG000001779_00982;MGYG000002919_00234;MGYG000002619_00737 domain d__Bacteria 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia 0.296875 186801|Clostridia 0.609375 E 0.890625 Psort location Cytoplasmic, score 9.98 0.328125 metY 0.546875 - 1.0 2.5.1.49 0.890625 ko:K01740 0.890625 ko00270,ko01100,map00270,map01100 0.890625 - 1.0 R01287,R04859 0.890625 RC00020,RC02821,RC02848 0.890625 ko00000,ko00001,ko01000 0.890625 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 0.609375 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02567 0.015625 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 0.890625 0.890625 0.890625 0.890625 Cysteine and methionine metabolism|Metabolic pathways 0.890625 K01740:metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] 0.890625 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GAGEKVNLDPAESVAYLIGK MGYG000004719_02002;MGYG000000271_02101 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004719_02002 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GAVHVTDYSNASR MGYG000001315_01111;MGYG000004733_00600;MGYG000004839_01969;MGYG000004689_01707;MGYG000002312_03080;MGYG000000213_01204;MGYG000000268_00688;MGYG000000245_01078;MGYG000003552_01937;MGYG000000145_02287;MGYG000000249_01696;MGYG000000142_00490;MGYG000004630_02409;MGYG000000164_01754;MGYG000004087_02483;MGYG000000271_02110;MGYG000002517_00523;MGYG000002186_01069;MGYG000000205_00108;MGYG000000501_01232;MGYG000000263_01173 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,27V84@189330|Dorea 0.3333333333333333 186801|Clostridia 1.0 F 0.42857142857142855 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01111 0.047619047619047616 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GAVVLPHGTGK MGYG000000139_00679;MGYG000002992_01641;MGYG000000095_03286;MGYG000002963_02025;MGYG000001698_00708;MGYG000004839_01328;MGYG000000171_01515;MGYG000003694_02390;MGYG000002193_01562;MGYG000002052_00803;MGYG000004762_01114;MGYG000000050_01365;MGYG000000201_02339;MGYG000004733_01323;MGYG000001027_00236;MGYG000000179_05050;MGYG000003695_01274;MGYG000000242_00769;MGYG000000152_04608;MGYG000003142_01874;MGYG000000028_00271;MGYG000000119_02509;MGYG000001571_03428;MGYG000000076_03547;MGYG000004680_00227;MGYG000002966_01277;MGYG000000251_00050;MGYG000000249_00046;MGYG000004296_01660;MGYG000001338_03534;MGYG000000387_00298;MGYG000000154_02173;MGYG000004634_00431;MGYG000000212_02414;MGYG000002552_01596;MGYG000001622_01986;MGYG000003425_04472;MGYG000001186_01608;MGYG000004604_00078;MGYG000001714_01227;MGYG000000087_02073;MGYG000004735_02574;MGYG000000268_01636;MGYG000002445_02953;MGYG000000269_00794;MGYG000002772_00853;MGYG000001303_01960;MGYG000000118_00315;MGYG000004630_01085;MGYG000001607_01030;MGYG000001687_02063;MGYG000001315_01189;MGYG000002517_00192;MGYG000002098_01611;MGYG000002286_02461;MGYG000000146_01144;MGYG000001748_00537;MGYG000002202_02038;MGYG000000271_03296;MGYG000000164_01129;MGYG000004380_01359;MGYG000000031_00709;MGYG000000153_01114;MGYG000002845_01899;MGYG000004714_00474;MGYG000000136_02022;MGYG000001689_01643;MGYG000002170_01019;MGYG000001065_00817;MGYG000003335_00786;MGYG000002393_01693;MGYG000000278_00573;MGYG000001439_02403;MGYG000002492_00336;MGYG000004519_00684;MGYG000001374_02225;MGYG000004717_00220;MGYG000001319_01772;MGYG000002298_02666;MGYG000000287_00086;MGYG000001658_02414;MGYG000000078_01689;MGYG000002670_00356;MGYG000000002_03534;MGYG000000198_05828;MGYG000000364_02037;MGYG000001660_01137;MGYG000002596_02351;MGYG000001683_01776;MGYG000004747_01843;MGYG000004246_01047;MGYG000000080_02021;MGYG000002279_01914;MGYG000000281_01919;MGYG000001688_00640;MGYG000003116_00418;MGYG000002312_03039;MGYG000000142_01261;MGYG000000562_01874;MGYG000002836_02018;MGYG000000187_02021;MGYG000002985_00771;MGYG000002528_01114;MGYG000000489_01684;MGYG000002835_01623;MGYG000000018_02173;MGYG000000140_01578;MGYG000000205_00361;MGYG000000274_00236;MGYG000000200_03209;MGYG000002072_00516;MGYG000001141_02451;MGYG000001379_00716;MGYG000003215_01171;MGYG000000133_01992;MGYG000004359_00731;MGYG000001637_00078;MGYG000004087_00328;MGYG000000252_00576 domain d__Bacteria 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 0.3277310924369748 186801|Clostridia 0.9831932773109243 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 0.9915966386554622 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000139_00679 0.008403361344537815 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GEFLLR MGYG000000532_01862 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-510|s__CAG-510 sp000434615|m__MGYG000000532 1.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,27IWP@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Aminoacyl tRNA synthetase class II, N-terminal domain 1.0 pheS 1.0 - 1.0 6.1.1.20 1.0 ko:K01889 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Phe_tRNA-synt_N,tRNA-synt_2d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000532_01862 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01889:FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GFGIAMHTLDGGR MGYG000000080_01475;MGYG000002528_02667;MGYG000000204_00801;MGYG000000127_04022;MGYG000001793_01807;MGYG000002945_00737;MGYG000001615_04301;MGYG000000139_01931;MGYG000001564_00904;MGYG000000164_00686;MGYG000001315_01868;MGYG000001814_02502;MGYG000001617_02045;MGYG000000028_00943;MGYG000003486_02522 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.4 186801|Clostridia 1.0 C 0.6 acyl-CoA dehydrogenase 0.4666666666666667 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_01475 0.06666666666666667 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 414206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GFPIAMHTLDGGR MGYG000000076_01275;MGYG000003694_00879;MGYG000001777_01058;MGYG000000280_01471;MGYG000000153_01461;MGYG000000136_00900;MGYG000001637_02229;MGYG000000271_02102;MGYG000000404_01797;MGYG000004271_00233;MGYG000000389_02149;MGYG000001186_01721;MGYG000002517_00542;MGYG000000489_01025;MGYG000001319_02235;MGYG000002670_01509;MGYG000002492_00659;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.6111111111111112 186801|Clostridia 1.0 C 0.8888888888888888 acyl-CoA dehydrogenase 0.6111111111111112 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000076_01275 0.05555555555555555 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GGGYTGQAGAIR MGYG000002992_01001;MGYG000002772_00676;MGYG000000249_02000;MGYG000004879_02699;MGYG000000262_00186;MGYG000000133_01062;MGYG000001439_02724;MGYG000001338_00476;MGYG000000213_02255;MGYG000000077_00860;MGYG000000171_01362;MGYG000000164_02705;MGYG000001186_01285;MGYG000000212_00914;MGYG000000271_01696;MGYG000000216_00022;MGYG000001141_01300;MGYG000002145_02436;MGYG000000806_00037;MGYG000002517_00289;MGYG000000187_01724;MGYG000000078_01638;MGYG000000038_02280;MGYG000001303_03153;MGYG000000562_01950;MGYG000000200_02986;MGYG000000159_01079;MGYG000001379_00626;MGYG000001652_01613;MGYG000004431_01330;MGYG000001315_01067;MGYG000000251_00358;MGYG000000201_02593;MGYG000000142_00583;MGYG000000301_01483;MGYG000000245_02146;MGYG000002945_03245;MGYG000004719_01698;MGYG000001374_02193;MGYG000004869_00363;MGYG000002312_00529;MGYG000002393_00234;MGYG000003012_00713;MGYG000002492_02720;MGYG000000050_00963;MGYG000000280_01393;MGYG000002966_01975;MGYG000000002_00954;MGYG000002279_00145;MGYG000000489_02402 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae 0.52 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 0.9 rpsI 1.0 - 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002992_01001 0.02 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02996:RP-S9, MRPS9, rpsI; small subunit ribosomal protein S9 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GGIVFAPKPR MGYG000004525_00964;MGYG000004487_01021;MGYG000002964_01300;MGYG000001476_03271;MGYG000000972_00369;MGYG000002707_00964;MGYG000001193_00545;MGYG000003819_01159;MGYG000004784_00635;MGYG000000099_02400;MGYG000002143_00708;MGYG000001616_02450;MGYG000004715_01182;MGYG000001733_00032;MGYG000003686_01083;MGYG000000668_02069;MGYG000002159_00259;MGYG000003589_01463;MGYG000001576_02390;MGYG000001328_03280;MGYG000002057_00234;MGYG000004736_00666;MGYG000004726_03515;MGYG000001685_00537;MGYG000004124_01019;MGYG000003278_01675;MGYG000000036_00624;MGYG000002315_01089;MGYG000004252_00062;MGYG000002115_00710;MGYG000000392_01460;MGYG000002926_00535;MGYG000002552_01618;MGYG000003142_01862;MGYG000002944_01721;MGYG000001500_00883;MGYG000003581_01700;MGYG000001781_02370;MGYG000002116_01180;MGYG000004201_00826;MGYG000001577_00648;MGYG000002229_01222;MGYG000000484_00176;MGYG000002794_00540;MGYG000004667_05135;MGYG000002953_00592;MGYG000004482_00988;MGYG000003459_00671;MGYG000002857_00040;MGYG000003453_00779;MGYG000003770_00994;MGYG000002727_02380;MGYG000004276_01040;MGYG000001502_00411;MGYG000000078_01672;MGYG000002993_00662;MGYG000001319_01323 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,2N6EK@216572|Oscillospiraceae 0.3508771929824561 186801|Clostridia 0.9824561403508771 J 0.9473684210526315 Forms part of the polypeptide exit tunnel 0.5964912280701754 rplD 0.9473684210526315 - 0.9824561403508771 - 0.9649122807017544 ko:K02926 0.9298245614035088 ko03010,map03010 0.9473684210526315 M00178 0.9473684210526315 - 0.9649122807017544 - 0.9649122807017544 br01610,ko00000,ko00001,ko00002,ko03011 0.9473684210526315 - 0.9824561403508771 - 1.0 - 1.0 Ribosomal_L4 0.9298245614035088 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004525_00964 0.017543859649122806 - - - - 0.9649122807017544 0.9649122807017544 0.9649122807017544 0.9649122807017544 Ribosome 0.9473684210526315 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 0.9298245614035088 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1115220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GGM(Oxidation)TSHAAVVAR MGYG000000236_00181;MGYG000002006_01658;MGYG000002685_01892;MGYG000004482_00393;MGYG000002298_01806;MGYG000002079_00687;MGYG000001415_02125;MGYG000002727_00240;MGYG000004680_00577;MGYG000004760_00878;MGYG000002560_01450;MGYG000001688_03814;MGYG000001698_00702;MGYG000004891_00190;MGYG000000378_00784;MGYG000001313_01473;MGYG000002103_01314;MGYG000002208_00666;MGYG000003116_01723;MGYG000004726_03204;MGYG000001374_00487;MGYG000001577_00663;MGYG000002517_01243;MGYG000002963_02777;MGYG000000074_01177;MGYG000002139_00077;MGYG000002933_01184;MGYG000004764_00308;MGYG000001665_01593;MGYG000000696_02522;MGYG000003801_01123;MGYG000002185_00531;MGYG000002545_01217;MGYG000000187_00493;MGYG000003236_01337;MGYG000000371_01679;MGYG000000262_01988;MGYG000003366_01811;MGYG000004468_01251;MGYG000000044_00817;MGYG000003223_01338;MGYG000000357_01205;MGYG000001641_02069;MGYG000000233_02503;MGYG000003221_00300;MGYG000004869_04101;MGYG000000111_01891;MGYG000000690_00823;MGYG000002455_03526;MGYG000003684_03260;MGYG000004630_00154;MGYG000001789_01569;MGYG000004797_01193;MGYG000001871_00692;MGYG000000194_03193;MGYG000002040_00906;MGYG000004296_00104;MGYG000000118_00274;MGYG000000039_02141;MGYG000002133_02142;MGYG000000312_02404;MGYG000000356_00934;MGYG000001496_03326;MGYG000001562_02560;MGYG000003821_02000;MGYG000000121_02531;MGYG000001502_03051;MGYG000002293_00252;MGYG000001356_00630;MGYG000004547_00698;MGYG000003312_03561;MGYG000000177_02155;MGYG000000231_00504;MGYG000002105_00879;MGYG000000002_01928;MGYG000004763_00142;MGYG000002965_00229;MGYG000002875_01930;MGYG000004667_00970;MGYG000001687_00537;MGYG000004735_00207;MGYG000003374_01797;MGYG000003921_00033;MGYG000002670_01671;MGYG000002590_00564;MGYG000001757_01805;MGYG000003979_01382;MGYG000002057_00345;MGYG000000728_00587;MGYG000002274_02693;MGYG000001531_01607;MGYG000000252_02480;MGYG000001136_01739;MGYG000000359_00714;MGYG000001306_00064;MGYG000000168_01244;MGYG000001345_02795;MGYG000000242_00224;MGYG000000212_00440;MGYG000003013_00135;MGYG000002794_01254;MGYG000004718_01489;MGYG000004733_01907;MGYG000003409_02325;MGYG000002580_00394;MGYG000003164_00707;MGYG000004545_00538;MGYG000004642_01131;MGYG000000170_00404;MGYG000000175_01356;MGYG000000076_02377;MGYG000001607_01964;MGYG000000159_02392;MGYG000000387_01345;MGYG000000184_00575;MGYG000000941_02014;MGYG000000281_03419;MGYG000002702_00763;MGYG000001489_03803;MGYG000000223_02468;MGYG000003899_02226;MGYG000004469_00050;MGYG000000154_00436;MGYG000000398_01662;MGYG000002102_01725;MGYG000002707_01357;MGYG000000045_00432;MGYG000001707_02428;MGYG000000255_02207;MGYG000001497_00744;MGYG000002212_01829;MGYG000002194_01689;MGYG000004871_01103;MGYG000002845_01363;MGYG000000198_00250;MGYG000002278_00689;MGYG000001732_00266;MGYG000002821_00845;MGYG000002945_01502;MGYG000003583_00265;MGYG000000133_02955;MGYG000004145_00052;MGYG000002191_00387;MGYG000003693_01476;MGYG000002279_01986;MGYG000000251_01169;MGYG000000153_02081;MGYG000001748_00979;MGYG000003166_00833;MGYG000000377_01737;MGYG000003628_00298;MGYG000000636_01370;MGYG000001191_01302;MGYG000002966_02744;MGYG000003656_02122;MGYG000000989_01009;MGYG000002219_00344;MGYG000003952_01418;MGYG000002925_01270;MGYG000003268_01036;MGYG000000202_02337;MGYG000001637_01169;MGYG000000087_02439;MGYG000001623_01332;MGYG000003285_00970;MGYG000000463_01481;MGYG000003222_00337;MGYG000000013_03892;MGYG000001597_00394;MGYG000001615_00145;MGYG000003662_00980;MGYG000002098_00511;MGYG000002609_02142;MGYG000001780_04079;MGYG000002926_01683;MGYG000002247_01703;MGYG000003681_00659;MGYG000003542_01534;MGYG000003539_00598;MGYG000000205_02701;MGYG000000152_05136;MGYG000003362_00767;MGYG000000028_00797;MGYG000001315_01921;MGYG000001300_02837;MGYG000004663_01541;MGYG000000743_01457;MGYG000000003_01500;MGYG000000352_00288;MGYG000004380_01725;MGYG000002025_01833;MGYG000004732_02304;MGYG000004475_00310;MGYG000003422_01232;MGYG000001328_00836;MGYG000002721_00889;MGYG000001541_00690;MGYG000000369_01165;MGYG000002549_01561;MGYG000001699_00078;MGYG000003702_00366;MGYG000002552_02286;MGYG000001346_03147;MGYG000003697_00469;MGYG000000404_01435;MGYG000002492_01692;MGYG000004784_01123;MGYG000003486_02360;MGYG000003512_01246;MGYG000004743_00400;MGYG000002218_01508;MGYG000000489_00801;MGYG000000394_00907;MGYG000000915_00888;MGYG000003446_00860;MGYG000003133_02846;MGYG000004464_01604;MGYG000000142_02834;MGYG000003891_00830;MGYG000002082_00584;MGYG000004866_01031;MGYG000000400_01783;MGYG000002099_01951;MGYG000000222_00273;MGYG000004487_00114;MGYG000000171_00241;MGYG000000280_02154;MGYG000003819_01577;MGYG000000325_02351;MGYG000004087_01282;MGYG000000245_03386;MGYG000003547_00119;MGYG000000258_01879;MGYG000000036_01410;MGYG000000179_00100;MGYG000003074_00103;MGYG000001367_01857;MGYG000003311_01206;MGYG000000217_00685;MGYG000001787_02320;MGYG000002934_01311;MGYG000000098_03346;MGYG000002026_01365;MGYG000000982_00638;MGYG000004634_00605;MGYG000001647_00185;MGYG000001423_03022;MGYG000001738_01167;MGYG000000201_02673;MGYG000003279_00708;MGYG000000022_02788;MGYG000000196_02017;MGYG000004558_03187;MGYG000003450_00463;MGYG000004810_00381;MGYG000002578_00642;MGYG000001754_01214;MGYG000001338_02151;MGYG000001675_00187;MGYG000001646_00500;MGYG000001666_00300;MGYG000002052_00198;MGYG000003202_01304;MGYG000001310_01399;MGYG000003432_00750;MGYG000003694_01656;MGYG000002675_00002;MGYG000001378_01176;MGYG000000077_02459;MGYG000002114_00088;MGYG000002229_00282;MGYG000002528_02478;MGYG000000701_00789;MGYG000001388_04287;MGYG000004594_00959;MGYG000000140_01464;MGYG000001461_02244;MGYG000002523_01400;MGYG000001157_01952;MGYG000001319_00729;MGYG000000145_01088;MGYG000000230_01645;MGYG000000115_00663;MGYG000002143_00035;MGYG000004317_00074;MGYG000000392_01615;MGYG000000243_00277;MGYG000003001_01218;MGYG000004271_01396;MGYG000001786_00858;MGYG000001660_00969;MGYG000002393_00923;MGYG000000127_02901;MGYG000000131_01163;MGYG000002935_00059;MGYG000000467_01756;MGYG000000268_00698;MGYG000002905_00879;MGYG000004517_00262;MGYG000000383_01314;MGYG000001733_00637;MGYG000004526_01655;MGYG000003708_02672;MGYG000003812_01931;MGYG000000354_02206;MGYG000003363_02147;MGYG000001756_01779;MGYG000004845_02015;MGYG000004879_02866;MGYG000001439_01567;MGYG000000806_02014;MGYG000001563_00781;MGYG000000174_00191;MGYG000002035_01821;MGYG000002304_00988;MGYG000000271_00388;MGYG000000417_00539;MGYG000002159_01291;MGYG000000278_00304;MGYG000004785_01840;MGYG000000031_02405;MGYG000000215_00031;MGYG000002478_03849;MGYG000002753_00264;MGYG000001619_00896;MGYG000000249_01089;MGYG000001505_00106;MGYG000000084_02524;MGYG000001364_03292;MGYG000003307_01519;MGYG000003469_00516;MGYG000001564_02842;MGYG000000099_03199;MGYG000002953_01784;MGYG000002438_03578;MGYG000004658_00597;MGYG000002007_01910;MGYG000002596_00549;MGYG000003142_00686;MGYG000004606_00249;MGYG000001661_00974;MGYG000000673_01172;MGYG000000164_00358;MGYG000003381_00006;MGYG000002224_02000;MGYG000000089_02490;MGYG000001255_00900;MGYG000001651_00429;MGYG000002126_00460;MGYG000003660_00478 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.22285714285714286 186801|Clostridia 0.7314285714285714 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8457142857142858 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9885714285714285 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000236_00181 0.002857142857142857 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GGMTSHAAVVAR MGYG000000236_00181;MGYG000002006_01658;MGYG000002685_01892;MGYG000004482_00393;MGYG000002298_01806;MGYG000002079_00687;MGYG000001415_02125;MGYG000002727_00240;MGYG000004680_00577;MGYG000004760_00878;MGYG000002560_01450;MGYG000001688_03814;MGYG000001698_00702;MGYG000004891_00190;MGYG000000378_00784;MGYG000001313_01473;MGYG000002103_01314;MGYG000002208_00666;MGYG000003116_01723;MGYG000004726_03204;MGYG000001374_00487;MGYG000001577_00663;MGYG000002517_01243;MGYG000002963_02777;MGYG000000074_01177;MGYG000002139_00077;MGYG000002933_01184;MGYG000004764_00308;MGYG000001665_01593;MGYG000000696_02522;MGYG000003801_01123;MGYG000002185_00531;MGYG000002545_01217;MGYG000000187_00493;MGYG000003236_01337;MGYG000000371_01679;MGYG000000262_01988;MGYG000003366_01811;MGYG000004468_01251;MGYG000000044_00817;MGYG000003223_01338;MGYG000000357_01205;MGYG000001641_02069;MGYG000000233_02503;MGYG000003221_00300;MGYG000004869_04101;MGYG000000111_01891;MGYG000000690_00823;MGYG000002455_03526;MGYG000003684_03260;MGYG000004630_00154;MGYG000001789_01569;MGYG000004797_01193;MGYG000001871_00692;MGYG000000194_03193;MGYG000002040_00906;MGYG000004296_00104;MGYG000000118_00274;MGYG000000039_02141;MGYG000002133_02142;MGYG000000312_02404;MGYG000000356_00934;MGYG000001496_03326;MGYG000001562_02560;MGYG000003821_02000;MGYG000000121_02531;MGYG000001502_03051;MGYG000002293_00252;MGYG000001356_00630;MGYG000004547_00698;MGYG000003312_03561;MGYG000000177_02155;MGYG000000231_00504;MGYG000002105_00879;MGYG000000002_01928;MGYG000004763_00142;MGYG000002965_00229;MGYG000002875_01930;MGYG000004667_00970;MGYG000001687_00537;MGYG000004735_00207;MGYG000003374_01797;MGYG000003921_00033;MGYG000002670_01671;MGYG000002590_00564;MGYG000001757_01805;MGYG000003979_01382;MGYG000002057_00345;MGYG000000728_00587;MGYG000002274_02693;MGYG000001531_01607;MGYG000000252_02480;MGYG000001136_01739;MGYG000000359_00714;MGYG000001306_00064;MGYG000000168_01244;MGYG000001345_02795;MGYG000000242_00224;MGYG000000212_00440;MGYG000003013_00135;MGYG000002794_01254;MGYG000004718_01489;MGYG000004733_01907;MGYG000003409_02325;MGYG000002580_00394;MGYG000003164_00707;MGYG000004545_00538;MGYG000004642_01131;MGYG000000170_00404;MGYG000000175_01356;MGYG000000076_02377;MGYG000001607_01964;MGYG000000159_02392;MGYG000000387_01345;MGYG000000184_00575;MGYG000000941_02014;MGYG000000281_03419;MGYG000002702_00763;MGYG000001489_03803;MGYG000000223_02468;MGYG000003899_02226;MGYG000004469_00050;MGYG000000154_00436;MGYG000000398_01662;MGYG000002102_01725;MGYG000002707_01357;MGYG000000045_00432;MGYG000001707_02428;MGYG000000255_02207;MGYG000001497_00744;MGYG000002212_01829;MGYG000002194_01689;MGYG000004871_01103;MGYG000002845_01363;MGYG000000198_00250;MGYG000002278_00689;MGYG000001732_00266;MGYG000002821_00845;MGYG000002945_01502;MGYG000003583_00265;MGYG000000133_02955;MGYG000004145_00052;MGYG000002191_00387;MGYG000003693_01476;MGYG000002279_01986;MGYG000000251_01169;MGYG000000153_02081;MGYG000001748_00979;MGYG000003166_00833;MGYG000000377_01737;MGYG000003628_00298;MGYG000000636_01370;MGYG000001191_01302;MGYG000002966_02744;MGYG000003656_02122;MGYG000000989_01009;MGYG000002219_00344;MGYG000003952_01418;MGYG000002925_01270;MGYG000003268_01036;MGYG000000202_02337;MGYG000001637_01169;MGYG000000087_02439;MGYG000001623_01332;MGYG000003285_00970;MGYG000000463_01481;MGYG000003222_00337;MGYG000000013_03892;MGYG000001597_00394;MGYG000001615_00145;MGYG000003662_00980;MGYG000002098_00511;MGYG000002609_02142;MGYG000001780_04079;MGYG000002926_01683;MGYG000002247_01703;MGYG000003681_00659;MGYG000003542_01534;MGYG000003539_00598;MGYG000000205_02701;MGYG000000152_05136;MGYG000003362_00767;MGYG000000028_00797;MGYG000001315_01921;MGYG000001300_02837;MGYG000004663_01541;MGYG000000743_01457;MGYG000000003_01500;MGYG000000352_00288;MGYG000004380_01725;MGYG000002025_01833;MGYG000004732_02304;MGYG000004475_00310;MGYG000003422_01232;MGYG000001328_00836;MGYG000002721_00889;MGYG000001541_00690;MGYG000000369_01165;MGYG000002549_01561;MGYG000001699_00078;MGYG000003702_00366;MGYG000002552_02286;MGYG000001346_03147;MGYG000003697_00469;MGYG000000404_01435;MGYG000002492_01692;MGYG000004784_01123;MGYG000003486_02360;MGYG000003512_01246;MGYG000004743_00400;MGYG000002218_01508;MGYG000000489_00801;MGYG000000394_00907;MGYG000000915_00888;MGYG000003446_00860;MGYG000003133_02846;MGYG000004464_01604;MGYG000000142_02834;MGYG000003891_00830;MGYG000002082_00584;MGYG000004866_01031;MGYG000000400_01783;MGYG000002099_01951;MGYG000000222_00273;MGYG000004487_00114;MGYG000000171_00241;MGYG000000280_02154;MGYG000003819_01577;MGYG000000325_02351;MGYG000004087_01282;MGYG000000245_03386;MGYG000003547_00119;MGYG000000258_01879;MGYG000000036_01410;MGYG000000179_00100;MGYG000003074_00103;MGYG000001367_01857;MGYG000003311_01206;MGYG000000217_00685;MGYG000001787_02320;MGYG000002934_01311;MGYG000000098_03346;MGYG000002026_01365;MGYG000000982_00638;MGYG000004634_00605;MGYG000001647_00185;MGYG000001423_03022;MGYG000001738_01167;MGYG000000201_02673;MGYG000003279_00708;MGYG000000022_02788;MGYG000000196_02017;MGYG000004558_03187;MGYG000003450_00463;MGYG000004810_00381;MGYG000002578_00642;MGYG000001754_01214;MGYG000001338_02151;MGYG000001675_00187;MGYG000001646_00500;MGYG000001666_00300;MGYG000002052_00198;MGYG000003202_01304;MGYG000001310_01399;MGYG000003432_00750;MGYG000003694_01656;MGYG000002675_00002;MGYG000001378_01176;MGYG000000077_02459;MGYG000002114_00088;MGYG000002229_00282;MGYG000002528_02478;MGYG000000701_00789;MGYG000001388_04287;MGYG000004594_00959;MGYG000000140_01464;MGYG000001461_02244;MGYG000002523_01400;MGYG000001157_01952;MGYG000001319_00729;MGYG000000145_01088;MGYG000000230_01645;MGYG000000115_00663;MGYG000002143_00035;MGYG000004317_00074;MGYG000000392_01615;MGYG000000243_00277;MGYG000003001_01218;MGYG000004271_01396;MGYG000001786_00858;MGYG000001660_00969;MGYG000002393_00923;MGYG000000127_02901;MGYG000000131_01163;MGYG000002935_00059;MGYG000000467_01756;MGYG000000268_00698;MGYG000002905_00879;MGYG000004517_00262;MGYG000000383_01314;MGYG000001733_00637;MGYG000004526_01655;MGYG000003708_02672;MGYG000003812_01931;MGYG000000354_02206;MGYG000003363_02147;MGYG000001756_01779;MGYG000004845_02015;MGYG000004879_02866;MGYG000001439_01567;MGYG000000806_02014;MGYG000001563_00781;MGYG000000174_00191;MGYG000002035_01821;MGYG000002304_00988;MGYG000000271_00388;MGYG000000417_00539;MGYG000002159_01291;MGYG000000278_00304;MGYG000004785_01840;MGYG000000031_02405;MGYG000000215_00031;MGYG000002478_03849;MGYG000002753_00264;MGYG000001619_00896;MGYG000000249_01089;MGYG000001505_00106;MGYG000000084_02524;MGYG000001364_03292;MGYG000003307_01519;MGYG000003469_00516;MGYG000001564_02842;MGYG000000099_03199;MGYG000002953_01784;MGYG000002438_03578;MGYG000004658_00597;MGYG000002007_01910;MGYG000002596_00549;MGYG000003142_00686;MGYG000004606_00249;MGYG000001661_00974;MGYG000000673_01172;MGYG000000164_00358;MGYG000003381_00006;MGYG000002224_02000;MGYG000000089_02490;MGYG000001255_00900;MGYG000001651_00429;MGYG000002126_00460;MGYG000003660_00478 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.22285714285714286 186801|Clostridia 0.7314285714285714 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8457142857142858 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9885714285714285 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000236_00181 0.002857142857142857 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GIDKAEIKR MGYG000002291_02272;MGYG000001630_01142;MGYG000000243_01988;MGYG000003691_01713 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002291_02272 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GIDKAEVKR MGYG000001770_01653;MGYG000002293_00521;MGYG000002603_01782;MGYG000003374_00521;MGYG000002080_00527;MGYG000003697_01485 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0050@1|root,COG0050@2|Bacteria,4P1C5@976|Bacteroidetes,2FX1Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001770_01653 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 295571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 731218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1163846 0 958471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GIDKNEIKR MGYG000000042_01421;MGYG000002905_00001;MGYG000000138_00665;MGYG000001661_02666;MGYG000004848_00666;MGYG000001789_00154;MGYG000000215_00564;MGYG000001925_01419;MGYG000000273_00431;MGYG000003701_03123;MGYG000000054_03933;MGYG000003681_02037;MGYG000000098_02017;MGYG000002470_01245;MGYG000002438_02321;MGYG000002556_01332;MGYG000001346_01533;MGYG000001313_00097;MGYG000004629_00424;MGYG000001763_00317;MGYG000000254_02569;MGYG000000044_01721;MGYG000002418_00753;MGYG000000117_01463;MGYG000002834_01866 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.48 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.04 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10816618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GIIVAPSK MGYG000002156_01453;MGYG000002720_01498;MGYG000004487_01572;MGYG000001824_01089;MGYG000002794_01483;MGYG000004475_01017 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,2N73E@216572|Oscillospiraceae 0.8333333333333334 186801|Clostridia 1.0 E 0.8333333333333334 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 0.8333333333333334 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002156_01453 0.16666666666666666 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GITINTSHVEYQTANR MGYG000000042_01421;MGYG000004756_01173;MGYG000001415_02515;MGYG000002438_02321;MGYG000004658_01205;MGYG000000053_00908;MGYG000000243_01988;MGYG000000013_02251;MGYG000004006_00433;MGYG000001562_01075;MGYG000000074_01773;MGYG000001789_00154;MGYG000003279_00951;MGYG000000273_00431;MGYG000001655_02933;MGYG000004763_01689;MGYG000002418_00753;MGYG000002291_02272;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000000168_03211 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 0.47619047619047616 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.047619047619047616 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 317584 0 0 0 0 0 0 806770 0 0 0 0 0 0 0 0 335987 0 284608 0 0 0 0 0 497469 0 0 0 0 0 0 0 0 0 0 0 0 0 470086 0 0 314072 0 425627 0 577272 0 0 0 0 0 0 0 0 440315 0 0 0 0 0 0 0 591085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166969 0 839484 0 0 0 0 0 0 0 0 0 0 317544 0 0 0 0 0 456545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 528060 0 0 630833 0 352546 0 332699 0 0 0 0 0 0 0 0 294021 0 400246 0 0 0 0 0 560877 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GLIVAPSK MGYG000002720_01498;MGYG000002794_01483;MGYG000001675_00492 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,2N73E@216572|Oscillospiraceae 0.6666666666666666 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 0.6666666666666666 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01498 0.3333333333333333 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GLLAYLK MGYG000000031_02386;MGYG000002298_00958;MGYG000000301_00463;MGYG000004733_02569;MGYG000000133_01737;MGYG000001314_02376;MGYG000000233_02689;MGYG000000200_01442;MGYG000001496_01208;MGYG000001698_03460;MGYG000001338_01245;MGYG000002274_00875;MGYG000000212_01974;MGYG000000171_00631;MGYG000000249_01938;MGYG000001310_00639;MGYG000001300_02374;MGYG000001602_02044;MGYG000004558_01263;MGYG000002438_01817;MGYG000000002_01947;MGYG000000184_00337;MGYG000001797_03146;MGYG000002966_03339;MGYG000000146_00467;MGYG000004869_04229;MGYG000004039_00267;MGYG000004735_01967;MGYG000002596_02036;MGYG000000142_02815;MGYG000002992_00137;MGYG000001970_01507;MGYG000000245_00310;MGYG000000245_02213;MGYG000000271_00460;MGYG000000245_00823;MGYG000002837_01061;MGYG000002492_01768;MGYG000002517_01666;MGYG000004519_01512;MGYG000000076_03321;MGYG000000038_02212;MGYG000000356_01426;MGYG000000119_01472;MGYG000000389_00299;MGYG000000268_01202;MGYG000000213_01727;MGYG000004271_01061;MGYG000003452_00551;MGYG000002279_00584;MGYG000003486_01734;MGYG000000201_02701;MGYG000000205_00957;MGYG000000216_02226;MGYG000004733_03076;MGYG000001186_00210 domain d__Bacteria 1.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia 0.23214285714285715 186801|Clostridia 0.75 J 0.6071428571428571 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 0.6071428571428571 rpsO 0.6071428571428571 - 1.0 - 0.9642857142857143 ko:K02956 0.6071428571428571 ko03010,map03010 0.6071428571428571 M00178,M00179 0.6071428571428571 - 0.7857142857142857 - 0.7857142857142857 br01610,ko00000,ko00001,ko00002,ko03011 0.6071428571428571 - 0.9464285714285714 - 1.0 - 1.0 Ribosomal_S15 0.6071428571428571 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_02386 0.017857142857142856 - - - - 0.9642857142857143 0.9642857142857143 0.9642857142857143 0.9642857142857143 Ribosome 0.6071428571428571 K02956:RP-S15, MRPS15, rpsO; small subunit ribosomal protein S15 0.6071428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3130645 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GMILC(Carbamidomethyl)KPGQVK MGYG000001789_00154;MGYG000000243_01988 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001789_00154 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GNFLMDELAR MGYG000000271_03444;MGYG000004271_01228 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_03444 0.5 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GPVASIC(Carbamidomethyl)YQGLMR MGYG000002560_02257;MGYG000001364_01116;MGYG000001787_02427;MGYG000004479_00625;MGYG000002933_00140;MGYG000000042_00775;MGYG000001306_01045;MGYG000003680_01392;MGYG000001599_02810;MGYG000004824_00039;MGYG000000781_01742;MGYG000003693_02590;MGYG000001783_00207;MGYG000002478_02040;MGYG000000442_00581;MGYG000000243_02202;MGYG000004763_00520;MGYG000000273_01192;MGYG000004797_01477 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 0.8947368421052632 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 0.8947368421052632 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002560_02257 0.05263157894736842 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 659162 0 0 0 0 645653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293361 0 0 0 0 494078 0 0 0 0 1940811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 854768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552681 0 0 0 0 734498 0 0 0 0 723787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 547978 0 0 0 0 514340 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GQKVNPHGLR MGYG000001365_00964;MGYG000002965_00664;MGYG000000249_01545;MGYG000004250_01651;MGYG000001367_00355;MGYG000001714_01322;MGYG000004517_00981;MGYG000004271_00022;MGYG000000177_02166;MGYG000001602_00386;MGYG000002953_00597;MGYG000002279_01066;MGYG000000187_01752;MGYG000000278_00919;MGYG000004769_00445;MGYG000001754_00745;MGYG000000362_00706;MGYG000000195_02127;MGYG000002619_02380;MGYG000002517_02867;MGYG000000515_01665;MGYG000001300_02209;MGYG000002298_00334;MGYG000002304_02165;MGYG000000071_01873;MGYG000000217_01260;MGYG000002528_01845;MGYG000002057_00239;MGYG000000140_01889;MGYG000001606_00218;MGYG000000198_04893;MGYG000000089_01490;MGYG000001315_01342;MGYG000002969_00164;MGYG000002312_02271;MGYG000000194_02276;MGYG000004680_02465;MGYG000000141_02175;MGYG000000139_02402;MGYG000004735_01595;MGYG000000262_00152;MGYG000003324_00575;MGYG000000334_01214;MGYG000000028_01616;MGYG000004593_00047;MGYG000004699_00276;MGYG000000050_01178;MGYG000000153_02048;MGYG000002105_00235;MGYG000002036_00649;MGYG000002154_01336;MGYG000003311_01156;MGYG000003876_00398;MGYG000000164_02758;MGYG000000022_02034;MGYG000000463_00749;MGYG000003422_00860;MGYG000000077_02604;MGYG000004558_00370;MGYG000001314_01374;MGYG000004317_00970;MGYG000000271_01067;MGYG000004736_00671;MGYG000000364_01346;MGYG000000146_01045;MGYG000000231_02152;MGYG000001576_02395;MGYG000001619_00828;MGYG000001338_02801;MGYG000004087_00388;MGYG000001626_01890;MGYG000004784_00630;MGYG000002966_02569;MGYG000004726_03510;MGYG000000258_00287;MGYG000003465_00837;MGYG000002290_02018;MGYG000000119_00095;MGYG000001191_00912;MGYG000000080_02261;MGYG000000171_01899;MGYG000004718_00068;MGYG000003215_00869;MGYG000002545_01134;MGYG000002276_00874;MGYG000000145_02795;MGYG000003895_00039;MGYG000003581_01705;MGYG000000245_02644;MGYG000000076_02814;MGYG000003147_00986;MGYG000001439_02149;MGYG000002113_00808;MGYG000000251_01825;MGYG000002159_00254;MGYG000002234_01447;MGYG000004681_01723;MGYG000004022_00110;MGYG000000591_02148;MGYG000002659_00451;MGYG000002492_00381;MGYG000001954_02309;MGYG000004296_00395;MGYG000000002_00876;MGYG000000179_04594;MGYG000004642_00857;MGYG000004727_00011;MGYG000000182_00577;MGYG000000099_02395 domain d__Bacteria 1.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae 0.2018348623853211 186801|Clostridia 0.908256880733945 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 0.9908256880733946 rpsC 0.9908256880733946 - 0.981651376146789 - 1.0 ko:K02982 0.9908256880733946 ko03010,map03010 0.9908256880733946 M00178,M00179 0.9908256880733946 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.9908256880733946 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 0.9908256880733946 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001365_00964 0.009174311926605505 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.9908256880733946 K02982:RP-S3, rpsC; small subunit ribosomal protein S3 0.9908256880733946 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GQVLAKPGTVTC(Carbamidomethyl)HR MGYG000000271_03365;MGYG000000532_02409;MGYG000000245_03248;MGYG000002670_00364;MGYG000001814_01592;MGYG000001319_01764 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_03365 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GTWDAVHAQAK MGYG000004482_00318 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4|s__ER4 sp900546295|m__MGYG000004482 1.0 COG0031@1|root,COG0031@2|Bacteria,1TZEW@1239|Firmicutes,249RW@186801|Clostridia,2N6W5@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Pyridoxal-phosphate dependent 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PALP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004482_00318 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 876007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80136 0 0 386616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GVDKNEIKR MGYG000000196_03974;MGYG000000236_01807;MGYG000004763_01689;MGYG000000013_02251;MGYG000002281_02290 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_03974 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GVNRDQIVR MGYG000000271_03365;MGYG000002670_00364;MGYG000001319_01764 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_03365 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GVWVFC(Carbamidomethyl)EQR MGYG000002105_00077;MGYG000002610_00221;MGYG000003166_01338;MGYG000000195_01569;MGYG000004487_01101;MGYG000003291_01730;MGYG000002794_00291;MGYG000000022_01320;MGYG000002707_00928;MGYG000001500_03165;MGYG000001824_01146;MGYG000000099_01610;MGYG000002059_01404;MGYG000002224_01329;MGYG000003937_01087;MGYG000004866_01546;MGYG000002651_00003;MGYG000000127_00940;MGYG000002040_01719;MGYG000001761_00373;MGYG000001157_00997;MGYG000003869_00111;MGYG000002619_02235;MGYG000000090_01517;MGYG000001300_00291;MGYG000004732_01392;MGYG000002287_01182;MGYG000002156_02067;MGYG000003899_01132;MGYG000001356_00011;MGYG000002223_00611;MGYG000001255_01110;MGYG000002287_00701;MGYG000004475_01038;MGYG000002720_01216;MGYG000002274_00049;MGYG000003770_01063 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 0.6216216216216216 186801|Clostridia 0.918918918918919 C 1.0 Electron transfer flavoprotein FAD-binding domain 0.6216216216216216 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 0.6216216216216216 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002105_00077 0.02702702702702703 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 5963920 0 0 0 0 0 0 4580095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2284218 0 0 0 0 2824027 0 2945233 0 0 0 0 0 0 0 0 0 0 0 0 2950549 0 2518740 0 0 0 2495733 0 0 0 0 3082236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)GYRPQFYFR MGYG000003096_01037;MGYG000004704_00398;MGYG000000303_01575;MGYG000004565_01266;MGYG000003189_00640;MGYG000004694_00667;MGYG000004893_00932;MGYG000003324_00542;MGYG000002563_00522;MGYG000001507_06245;MGYG000004685_00908;MGYG000001739_00819;MGYG000003184_03610;MGYG000003363_01661;MGYG000003411_00716;MGYG000004594_01333;MGYG000001234_01151;MGYG000003185_01074;MGYG000001623_00993;MGYG000003142_01879;MGYG000002994_01317;MGYG000003208_02857;MGYG000002563_00509;MGYG000003266_00392;MGYG000004119_01204;MGYG000002515_03657;MGYG000003189_01066;MGYG000003142_01865;MGYG000002557_00102;MGYG000004800_00190;MGYG000001713_03599;MGYG000004769_00437;MGYG000003851_00676;MGYG000003022_00748;MGYG000000371_01541;MGYG000000349_00457;MGYG000002098_01616;MGYG000003274_01474;MGYG000004528_00894;MGYG000003868_01133;MGYG000001359_01254;MGYG000004722_01495;MGYG000000333_00136;MGYG000001692_03322;MGYG000002996_00986;MGYG000003753_00317;MGYG000002506_03686;MGYG000003352_00730;MGYG000002447_00587;MGYG000001365_00649;MGYG000002854_00111;MGYG000004769_00412;MGYG000001524_01606;MGYG000002485_02622;MGYG000003022_00735;MGYG000003528_02124;MGYG000004724_00878;MGYG000004893_01944;MGYG000000802_00776;MGYG000000372_00001;MGYG000000365_00508;MGYG000002535_04656;MGYG000002515_03208;MGYG000003372_03275;MGYG000000291_00377;MGYG000000266_00259;MGYG000001464_00103;MGYG000002447_00574;MGYG000000449_00614;MGYG000002506_02966;MGYG000000120_01190;MGYG000001404_04883;MGYG000000375_01434;MGYG000002901_00528;MGYG000002514_02415;MGYG000001436_02249;MGYG000003891_00382;MGYG000001525_00035;MGYG000000157_01091;MGYG000003394_01668;MGYG000000490_01981;MGYG000001784_02227;MGYG000003110_00861;MGYG000002507_00346;MGYG000001485_02164;MGYG000002195_01684;MGYG000000479_00469;MGYG000001991_00383;MGYG000003465_01528;MGYG000001638_00284;MGYG000003977_00001;MGYG000003868_01166;MGYG000000024_03409;MGYG000001677_00114;MGYG000000432_00837;MGYG000003170_00035;MGYG000001590_00854;MGYG000002972_00178;MGYG000002098_00731;MGYG000002514_01953;MGYG000002912_01340;MGYG000000121_02189;MGYG000001567_01738;MGYG000003441_00074;MGYG000003389_01825;MGYG000004694_00680;MGYG000002502_01846;MGYG000000945_00137;MGYG000002854_00124;MGYG000002830_01189;MGYG000003185_01053;MGYG000003170_00048;MGYG000004746_00230;MGYG000000121_03149;MGYG000001665_01696;MGYG000004657_01190;MGYG000003504_00096;MGYG000000405_00711;MGYG000001646_01118;MGYG000003514_00785;MGYG000002970_01555;MGYG000001007_01315;MGYG000002659_00459;MGYG000004047_00605 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CUFV@84998|Coriobacteriia 0.12903225806451613 186801|Clostridia 0.41935483870967744 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9032258064516129 tuf 1.0 - 0.9032258064516129 - 1.0 ko:K02358 0.9919354838709677 - 0.9919354838709677 - 0.9919354838709677 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9919354838709677 - 0.9919354838709677 - 1.0 - 0.9435483870967742 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003096_01037 0.008064516129032258 - - - - 1.0 1.0 1.0 1.0 - 0.9919354838709677 K02358:tuf, TUFM; elongation factor Tu 0.9919354838709677 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)HTIDNLDNISENTSSAESR MGYG000003694_00680;MGYG000003694_02093 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter faecis|m__MGYG000003694 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_00680 0.5 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 652115 0 0 0 0 1748007 0 0 0 0 882111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)IDAFIR MGYG000004839_01245 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__GCA-900066135|s__|m__MGYG000004839 1.0 COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Acetolactate synthase, small subunit 1.0 ilvN 1.0 - 1.0 2.2.1.6 1.0 ko:K01653 1.0 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R00006,R00014,R00226,R03050,R04672,R04673,R08648 1.0 RC00027,RC00106,RC01192,RC02744,RC02893 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS10025 1.0 ACT,ACT_5,ALS_ss_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004839_01245 1.0 acetolactate synthase. alpha-acetolactate synthetase. The reaction shown is in the pathway of biosynthesis of valine.-!-The enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine.-!-Formerly EC 4.1.3.18. H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Butanoate metabolism|C5-Branched dibasic acid metabolism|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K01653:E2.2.1.6S, ilvH, ilvN; acetolactate synthase I/III small subunit [EC:2.2.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1386468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1571383 0 0 0 0 0 0 +(Carbamidomethyl)IDPLIGLK MGYG000000142_00116;MGYG000000262_00026 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3XYSW@572511|Blautia 0.5 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000000142_00116 0.5 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)IEEVVAK MGYG000000213_02548;MGYG000000053_00926;MGYG000001787_01168;MGYG000002082_01733;MGYG000001364_00770;MGYG000000003_02420;MGYG000001346_02612;MGYG000002549_00764;MGYG000003539_00163;MGYG000001338_01196;MGYG000004185_02468;MGYG000000074_01808;MGYG000001630_00403;MGYG000000105_03037;MGYG000000224_00951;MGYG000002133_01046;MGYG000003542_01378;MGYG000003469_00458;MGYG000000200_03517;MGYG000001313_02533;MGYG000001750_00845;MGYG000004658_01241;MGYG000001789_01807;MGYG000001420_00031;MGYG000001835_00447;MGYG000002560_01566;MGYG000003922_03262;MGYG000002905_00830;MGYG000000273_00915;MGYG000004536_01855;MGYG000002108_00182;MGYG000003279_00867;MGYG000000243_01732;MGYG000000354_00645;MGYG000003681_01014;MGYG000004479_00195;MGYG000001360_00725;MGYG000000042_00518;MGYG000001429_01341;MGYG000004763_00341 domain d__Bacteria 1.0 COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia,4AKD2@815|Bacteroidaceae 0.475 976|Bacteroidetes 0.925 S 0.825 Endoribonuclease that initiates mRNA decay 0.925 rny 0.925 - 1.0 - 0.925 ko:K18682 0.925 ko03018,map03018 0.925 - 1.0 - 0.925 - 0.925 ko00000,ko00001,ko01000,ko03019 0.925 - 1.0 - 1.0 - 1.0 DUF3552,HD,KH_1 0.925 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000213_02548 0.025 - - - - 0.925 0.925 0.925 0.925 RNA degradation 0.925 K18682:rny; ribonucrease Y [EC:3.1.-.-] 0.925 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)IESVAR MGYG000004464_01712 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Barnesiellaceae|g__Barnesiella|s__Barnesiella sp900542255|m__MGYG000004464 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22WR5@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004464_01712 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5845798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)IGEGLHTVEAGEGSIIVDGK MGYG000000392_01140 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Ruminococcus_E|s__Ruminococcus_E sp003521625|m__MGYG000000392 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000392_01140 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1153943 0 0 0 0 1190018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)IIAYLK MGYG000002478_02508;MGYG000003922_03572;MGYG000002171_00339;MGYG000000196_03221;MGYG000000243_02815 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FNVV@200643|Bacteroidia,4AM0Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 pepD_1 1.0 - 1.0 - 1.0 ko:K01270 1.0 ko00480,ko01100,map00480,map01100 1.0 - 1.0 R00899,R04951 1.0 RC00096,RC00141 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02508 0.2 - - - - 1.0 1.0 1.0 1.0 Glutathione metabolism|Metabolic pathways 1.0 K01270:pepD; dipeptidase D [EC:3.4.13.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 3181591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)IINEPTAAALAYGLDNEKEQK MGYG000003366_02143;MGYG000000175_03865;MGYG000003355_02854;MGYG000001615_03019;MGYG000000255_01223;MGYG000000249_01105;MGYG000000181_00382;MGYG000002989_00635;MGYG000000171_01795;MGYG000000152_05170;MGYG000001689_04245;MGYG000002492_01740;MGYG000002772_01367;MGYG000000271_02474;MGYG000000038_00915;MGYG000003694_01621;MGYG000000142_01918;MGYG000000233_02915;MGYG000004842_01083;MGYG000004547_01722;MGYG000000287_03181;MGYG000001303_03339;MGYG000000133_02344;MGYG000004642_01648;MGYG000004271_00836;MGYG000000198_01270;MGYG000002393_02714;MGYG000000141_02906;MGYG000002234_00982;MGYG000003422_00551;MGYG000003012_00270;MGYG000002276_02250;MGYG000000123_02326;MGYG000004285_01970;MGYG000000200_01023;MGYG000002286_01322;MGYG000000002_00433;MGYG000004869_03374;MGYG000000278_01716;MGYG000000139_01467;MGYG000000281_00071;MGYG000000179_03775;MGYG000000245_00866;MGYG000001310_00050;MGYG000001247_01563;MGYG000001315_00535;MGYG000004733_01142;MGYG000004087_01928;MGYG000004735_00816;MGYG000000127_03199;MGYG000002279_01669;MGYG000001619_00480;MGYG000002256_00937;MGYG000001698_00974;MGYG000001065_01063;MGYG000000164_00503;MGYG000000153_02121;MGYG000002517_00989;MGYG000003821_01669;MGYG000001374_00251;MGYG000001496_00605;MGYG000001617_02693;MGYG000004762_01166;MGYG000000217_02058 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.375 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003366_02143 0.015625 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)ILPLEKNPDFVGTRK MGYG000004271_01228 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01228 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)ILVTLLHEMQKR MGYG000004525_00228;MGYG000002953_03277;MGYG000002670_01511;MGYG000002727_00924;MGYG000004769_00635;MGYG000003215_01534;MGYG000001356_02661;MGYG000002156_00131;MGYG000002720_01849;MGYG000000164_00683;MGYG000001814_02499;MGYG000001616_02334;MGYG000001637_02269;MGYG000001500_00694;MGYG000004628_02379;MGYG000001711_01126;MGYG000003589_00853;MGYG000002492_00657;MGYG000002099_02958;MGYG000000204_00804;MGYG000000997_00552;MGYG000000077_02464;MGYG000002926_00108;MGYG000002143_01933;MGYG000000280_01473;MGYG000002485_00796;MGYG000003074_00590;MGYG000002673_02531;MGYG000000389_02151;MGYG000000262_02231;MGYG000001793_01810;MGYG000004271_00231;MGYG000000245_02019;MGYG000000271_02104;MGYG000002517_00540;MGYG000004475_01257;MGYG000001315_01871 domain d__Bacteria 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,2N6SP@216572|Oscillospiraceae 0.32432432432432434 186801|Clostridia 0.918918918918919 I 1.0 Belongs to the thiolase family 0.5135135135135135 thlA 0.918918918918919 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004525_00228 0.02702702702702703 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)ISIKDTR MGYG000003374_00261;MGYG000000117_02272;MGYG000004733_01798;MGYG000004469_01045;MGYG000001211_00617;MGYG000001777_01726;MGYG000001356_01504;MGYG000003539_00358;MGYG000002534_00332;MGYG000003352_01970;MGYG000000146_00711;MGYG000000258_01582;MGYG000000463_00946;MGYG000004735_01737;MGYG000003282_01713;MGYG000002082_01050;MGYG000002042_01173;MGYG000001607_01410;MGYG000001489_01493;MGYG000000187_01632;MGYG000002438_01730;MGYG000004629_01198;MGYG000000201_03541;MGYG000000196_01785;MGYG000000164_00409;MGYG000004830_00640;MGYG000000231_00052;MGYG000003022_01459;MGYG000000369_01798;MGYG000000233_02484;MGYG000003621_01331;MGYG000003984_00341;MGYG000000182_00198;MGYG000002274_02526;MGYG000003546_01574;MGYG000000154_00030;MGYG000001637_01423;MGYG000000325_00559;MGYG000000268_00827;MGYG000000312_01303;MGYG000003353_02290;MGYG000001164_02313;MGYG000003063_03432;MGYG000001531_02004;MGYG000000398_00128;MGYG000002203_00985;MGYG000002772_01784;MGYG000002532_00097;MGYG000002279_00233;MGYG000000038_01227;MGYG000003204_01991;MGYG000001374_02763;MGYG000001065_01729;MGYG000002494_02064;MGYG000002619_01587;MGYG000002549_03009;MGYG000000249_00741;MGYG000000255_01277;MGYG000000359_02374;MGYG000001456.1_02555;MGYG000001754_01464;MGYG000001346_02112;MGYG000004271_00099;MGYG000003694_01770;MGYG000003695_03029;MGYG000000174_04897;MGYG000000074_00119;MGYG000001319_00792;MGYG000004757_00433;MGYG000001608_01372;MGYG000004638_00366;MGYG000001733_01436;MGYG000000140_02799;MGYG000002312_02047;MGYG000002007_01949;MGYG000000150_00934;MGYG000000650_01803;MGYG000002113_00157;MGYG000004296_01453;MGYG000000184_00227;MGYG000002290_01715;MGYG000000242_01153;MGYG000000193_03368;MGYG000000084_02464;MGYG000002298_02427;MGYG000000217_00585;MGYG000004822_01333;MGYG000003554_01585;MGYG000000673_00661;MGYG000000031_03161;MGYG000000212_01493;MGYG000001447_01495;MGYG000000622_01660;MGYG000000171_00870;MGYG000001302.1_01989;MGYG000002445_00666;MGYG000000271_02023;MGYG000002506_03025;MGYG000002641_01086;MGYG000004762_00297;MGYG000004558_00126;MGYG000002145_02237;MGYG000000078_00400;MGYG000000236_04489;MGYG000000022_02853;MGYG000000170_00471;MGYG000000562_01754;MGYG000002966_02362;MGYG000002212_01428;MGYG000002455_01424;MGYG000001337_04099;MGYG000000133_00275;MGYG000001602_01331;MGYG000000414_01708;MGYG000000044_02644;MGYG000000404_00613;MGYG000000589_00852;MGYG000003363_00033;MGYG000001315_01422;MGYG000001345_04617;MGYG000000142_01678;MGYG000001300_02311;MGYG000000412_00523;MGYG000004658_01689;MGYG000003291_00979;MGYG000001655_03297;MGYG000004536_00920;MGYG000001551_02111;MGYG000003681_02208;MGYG000003702_01556;MGYG000002517_01999;MGYG000002535_04602;MGYG000000050_00443;MGYG000000003_00469;MGYG000004747_00335;MGYG000001415_01110;MGYG000003937_01472;MGYG000001338_02508;MGYG000002721_02375;MGYG000003252_01528 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia 0.37142857142857144 186801|Clostridia 0.5928571428571429 H 0.9428571428571428 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 0.9928571428571429 pckA 0.9928571428571429 - 0.6428571428571429 4.1.1.49 0.9785714285714285 ko:K01610 0.9785714285714285 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 0.9785714285714285 M00003,M00170 0.9785714285714285 R00341 0.9785714285714285 RC00002,RC02741 0.9785714285714285 ko00000,ko00001,ko00002,ko01000 0.9785714285714285 - 1.0 - 1.0 - 0.9714285714285714 PEPCK_ATP 0.9928571428571429 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003374_00261 0.007142857142857143 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 0.9785714285714285 0.9785714285714285 0.9785714285714285 0.9785714285714285 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 0.9785714285714285 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 0.9785714285714285 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)ISTEIGKSPVQVNEAAGFVVNR MGYG000001157_01000;MGYG000004866_01549 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001157_01000 0.5 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 758184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1406795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1158768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 787703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 711052 0 0 0 0 +(Carbamidomethyl)ITEIYEGTSEVQR MGYG000002229_02144;MGYG000003589_02740;MGYG000000076_01275;MGYG000001714_01569;MGYG000003554_00067;MGYG000004740_00273;MGYG000002673_02001;MGYG000001615_04301;MGYG000002673_01997;MGYG000004610_01222;MGYG000000153_01461;MGYG000002057_01870;MGYG000002086_01703;MGYG000001637_02229;MGYG000003686_01365;MGYG000002926_00639;MGYG000000489_01025;MGYG000002670_01509;MGYG000002492_00659;MGYG000001299_00669;MGYG000004628_02311;MGYG000002528_02667;MGYG000001797_02605;MGYG000002964_00486;MGYG000001008_02486;MGYG000000312_02425;MGYG000001302.1_00495;MGYG000000127_04022;MGYG000002944_01934;MGYG000001793_01807;MGYG000000139_01931;MGYG000000532_01532;MGYG000001356_00009;MGYG000000378_01674;MGYG000001655_02978;MGYG000004475_01030;MGYG000000271_02102;MGYG000000404_01797;MGYG000004271_00233;MGYG000004039_00586;MGYG000002794_01608;MGYG000001814_02502;MGYG000001186_01721;MGYG000001199_01107;MGYG000000028_00943;MGYG000000223_02387;MGYG000001319_02235;MGYG000000262_02234;MGYG000003486_02522;MGYG000000154_01282;MGYG000002035_01743;MGYG000004487_00391;MGYG000004288_00482;MGYG000002485_00623;MGYG000002882_00479;MGYG000002143_01787;MGYG000000205_02133;MGYG000000378_01663;MGYG000002156_01815;MGYG000000164_00686;MGYG000001500_03163;MGYG000004893_01404;MGYG000003074_00587;MGYG000004196_00482;MGYG000002974_01094;MGYG000000099_01612;MGYG000001502_00068;MGYG000000255_01556;MGYG000001315_01868;MGYG000003753_00746;MGYG000002720_01506;MGYG000001617_02045;MGYG000003649_02139;MGYG000003828_00184;MGYG000000080_01475;MGYG000000018_00071;MGYG000000077_02467;MGYG000000204_00801;MGYG000003694_00879;MGYG000001777_01058;MGYG000002278_01893;MGYG000000121_03669;MGYG000000280_01471;MGYG000002945_00737;MGYG000000930_01661;MGYG000001327_01004;MGYG000001749_01450;MGYG000001460_01831;MGYG000000136_00900;MGYG000001683_00189;MGYG000000086_01916;MGYG000000389_02149;MGYG000002934_01789;MGYG000001675_00811;MGYG000004762_01001;MGYG000002517_00542 domain d__Bacteria 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2N683@216572|Oscillospiraceae 0.17708333333333334 186801|Clostridia 0.8333333333333334 I 0.53125 Acyl-CoA dehydrogenase, C-terminal domain 0.3645833333333333 bcd 0.875 - 1.0 1.3.8.1 0.90625 ko:K00248 0.90625 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 0.9375 - 1.0 R01175,R01178,R02661,R03172,R04751 0.9375 RC00052,RC00068,RC00076,RC00120,RC00148 0.9375 ko00000,ko00001,ko01000 0.9375 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 0.6770833333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002229_02144 0.010416666666666666 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 0.90625 0.90625 0.90625 0.90625 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 0.9375 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 0.90625 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)KDITGLGLK MGYG000004468_00169 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900539755|m__MGYG000004468 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00169 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)KIEAAVDTK MGYG000003681_02191 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_02191 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3298246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)KLLDQGEAGDNVGLLLR MGYG000000042_01421;MGYG000000196_03974;MGYG000000138_00665;MGYG000004704_00398;MGYG000001661_02666;MGYG000001630_01142;MGYG000003424_00456;MGYG000001789_00154;MGYG000000273_00431;MGYG000000236_01807;MGYG000003701_03123;MGYG000000054_03933;MGYG000004763_01689;MGYG000003681_02037;MGYG000000098_02017;MGYG000002291_02272;MGYG000002281_02290;MGYG000002470_01245;MGYG000002438_02321;MGYG000001346_01533;MGYG000001313_00097;MGYG000000243_01988;MGYG000000013_02251;MGYG000001780_03476;MGYG000001562_01075;MGYG000002455_03884;MGYG000003497_00215;MGYG000000044_01721;MGYG000002418_00753;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.4666666666666667 976|Bacteroidetes 0.9666666666666667 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.03333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)KSDLTGAVSAISADK MGYG000003520_00430 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__UBA932|g__RC9|s__RC9 sp900769145|m__MGYG000003520 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AWE5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003520_00430 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2328065 0 0 0 0 2499584 0 0 0 0 2045847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850805 0 0 0 0 932510 0 0 0 0 753708 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)KTVVTGIEMFRK MGYG000004743_00349;MGYG000000251_00064;MGYG000003236_02455;MGYG000000121_02189;MGYG000000099_01234;MGYG000003486_01055;MGYG000002772_01895;MGYG000002492_00344;MGYG000000255_02009;MGYG000002052_00232;MGYG000000164_01096;MGYG000001606_01669;MGYG000001698_04050;MGYG000001310_01963 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.2857142857142857 186801|Clostridia 0.9285714285714286 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004743_00349 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)LFVVDAFC(Carbamidomethyl)GANKDTR MGYG000000268_00827;MGYG000001733_01436;MGYG000000179_01927;MGYG000000347_00991;MGYG000000140_02799;MGYG000002312_02047;MGYG000001615_04787;MGYG000002670_02163;MGYG000000150_00934;MGYG000000562_01754;MGYG000004296_01453;MGYG000000184_00227;MGYG000000245_00268;MGYG000002772_01784;MGYG000000463_00946;MGYG000000404_00613;MGYG000000084_02464;MGYG000000217_00585;MGYG000000187_01632;MGYG000000142_01678;MGYG000000201_03541;MGYG000000031_03161;MGYG000002492_01827;MGYG000001311_00844;MGYG000000249_00741;MGYG000000255_01277;MGYG000000095_02727;MGYG000000233_02484;MGYG000004740_01746;MGYG000004891_01172;MGYG000002445_00666;MGYG000002517_01999;MGYG000000198_03217;MGYG000004271_00099;MGYG000000271_02023;MGYG000003694_01770;MGYG000003695_03029;MGYG000004558_00126;MGYG000002145_02237;MGYG000004747_00335;MGYG000000489_00960;MGYG000003486_01799;MGYG000000078_00400;MGYG000000251_02509;MGYG000001637_01423;MGYG000003937_01472;MGYG000001338_02508;MGYG000000325_00559 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia 0.6875 186801|Clostridia 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000268_00827 0.020833333333333332 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)LGYDDATIADYLAK MGYG000004642_00725 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,36FMV@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 PFAM L-carnitine dehydratase bile acid-inducible protein F 1.0 hadA 1.0 - 1.0 2.8.3.24 1.0 ko:K20882 1.0 - 1.0 - 1.0 R11462 1.0 RC00014,RC00137 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_transf_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004642_00725 1.0 (R)-2-hydroxy-4-methylpentanoate CoA-transferase. - The enzyme, characterized from the bacterium Peptoclostridium difficile, participates in an L-leucine fermentation pathway.-!-The reaction proceeds via formation of a covalent anhydride intermediate between a conserved aspartate residue and the acyl group of the CoA thioester substrate. (R)-2-hydroxy-4-methylpentanoate + 4-methylpentanoyl-CoA = (R)-2-hydroxy- 4-methylpentanoyl-CoA + 4-methylpentanoate. 1.0 1.0 1.0 1.0 - 1.0 K20882:hadA; (R)-2-hydroxy-4-methylpentanoate CoA-transferase [EC:2.8.3.24] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1594056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)LIAYLK MGYG000002478_02508;MGYG000002171_00339;MGYG000000243_02815 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FNVV@200643|Bacteroidia,4AM0Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 pepD_1 1.0 - 1.0 - 1.0 ko:K01270 1.0 ko00480,ko01100,map00480,map01100 1.0 - 1.0 R00899,R04951 1.0 RC00096,RC00141 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02508 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Glutathione metabolism|Metabolic pathways 1.0 K01270:pepD; dipeptidase D [EC:3.4.13.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1983138 0 0 0 0 2202369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3294908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)LIDGGYDGK MGYG000000217_02098;MGYG000001310_01635;MGYG000002247_02055 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,27IZ4@186928|unclassified Lachnospiraceae 0.6666666666666666 186801|Clostridia 1.0 P 1.0 TOBE domain 0.6666666666666666 ugpC_1 1.0 - 1.0 - 1.0 ko:K10112 1.0 ko02010,map02010 1.0 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1 1.0 - 1.0 - 1.0 ABC_tran,TOBE,TOBE_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000217_02098 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10112:msmX, msmK, malK, sugC, ggtA, msiK; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4272409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)LLDEAQAGDNIGALLR MGYG000000080_02058;MGYG000000171_02844;MGYG000002279_01932;MGYG000000201_03875;MGYG000001688_04229;MGYG000004735_00884;MGYG000000280_01200;MGYG000000198_01165;MGYG000001315_01207;MGYG000000133_02991;MGYG000001602_02247;MGYG000001310_01963;MGYG000003273_00234;MGYG000000140_01590;MGYG000003142_01879;MGYG000002528_01098;MGYG000004680_02443;MGYG000002609_01147;MGYG000002202_00030;MGYG000000263_00836;MGYG000001619_01314;MGYG000000179_00920;MGYG000000216_02406;MGYG000002290_01325;MGYG000004296_01668;MGYG000001607_01045;MGYG000001141_02439;MGYG000003142_01865;MGYG000000251_00064;MGYG000001338_03373;MGYG000000139_00697;MGYG000000142_00171;MGYG000001528_00736;MGYG000000404_00531;MGYG000004087_00551;MGYG000001439_02427;MGYG000002417_01244;MGYG000000164_01096;MGYG000002126_00299;MGYG000002234_01026;MGYG000000212_03313;MGYG000001698_04050;MGYG000003074_01359;MGYG000000032_01232;MGYG000002837_02416;MGYG000000193_02083;MGYG000002212_00196;MGYG000000249_00026;MGYG000004799_01385;MGYG000002136_02858;MGYG000004630_01824;MGYG000002286_02469;MGYG000001814_01592;MGYG000000262_00030;MGYG000003486_01055;MGYG000002772_01895;MGYG000001617_01406;MGYG000002596_02296;MGYG000004733_01211 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 0.3220338983050847 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_02058 0.01694915254237288 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 584343 0 0 0 0 0 0 0 0 0 0 630928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520573 0 0 0 0 0 0 0 0 0 0 348112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)LLDQGEAGDNVGLLLR MGYG000000042_01421;MGYG000000196_03974;MGYG000000138_00665;MGYG000004704_00398;MGYG000001661_02666;MGYG000001630_01142;MGYG000003424_00456;MGYG000001789_00154;MGYG000000273_00431;MGYG000000236_01807;MGYG000003701_03123;MGYG000000054_03933;MGYG000004763_01689;MGYG000003681_02037;MGYG000000098_02017;MGYG000002291_02272;MGYG000002281_02290;MGYG000002470_01245;MGYG000002438_02321;MGYG000001346_01533;MGYG000001313_00097;MGYG000000243_01988;MGYG000000013_02251;MGYG000001780_03476;MGYG000001562_01075;MGYG000002455_03884;MGYG000003497_00215;MGYG000000044_01721;MGYG000002418_00753;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.4666666666666667 976|Bacteroidetes 0.9666666666666667 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.03333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)LQSLVFDR MGYG000003376_01015 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Leptotrichiaceae|g__Sneathia|s__Sneathia sanguinegens|m__MGYG000003376 1.0 COG0173@1|root,COG0173@2|Bacteria,37982@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) 1.0 aspS 1.0 - 1.0 6.1.1.12 1.0 ko:K01876 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R05577 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 GAD,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon 1.0 - 1.0 - 1.0 - 1.0 GT83 1.0 MGYG000003376_01015 1.0 aspartate--tRNA ligase. aspartyl-tRNA synthetase. - ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01876:DARS2, aspS; aspartyl-tRNA synthetase [EC:6.1.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4143607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)LSAAEVETLLR MGYG000001415_00893 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,22UVQ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_00893 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 595685 0 0 0 0 0 0 0 0 0 773301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)LVVFMNK MGYG000000080_02058;MGYG000001389_01588;MGYG000000171_02844;MGYG000004732_02398;MGYG000001673_01975;MGYG000000089_01901;MGYG000001688_04229;MGYG000002619_00483;MGYG000001654_02237;MGYG000004718_00646;MGYG000004735_00884;MGYG000000280_01200;MGYG000003547_00975;MGYG000001714_01291;MGYG000001760_00949;MGYG000000198_01165;MGYG000000392_00966;MGYG000003681_02037;MGYG000000133_02991;MGYG000001389_00024;MGYG000003185_01074;MGYG000003992_01709;MGYG000002202_00030;MGYG000001313_00097;MGYG000003895_00135;MGYG000001619_01314;MGYG000002455_03884;MGYG000000216_02406;MGYG000000348_00283;MGYG000002364_00543;MGYG000000044_01721;MGYG000000034_01346;MGYG000004296_01668;MGYG000003549_00407;MGYG000001469_02077;MGYG000002059_00460;MGYG000001809_00576;MGYG000001652_01300;MGYG000000127_03982;MGYG000001434_01407;MGYG000000258_00266;MGYG000001338_03373;MGYG000001300_00280;MGYG000001611_00087;MGYG000002762_01733;MGYG000000371_01541;MGYG000000255_02009;MGYG000002040_01212;MGYG000000164_01096;MGYG000004826_01022;MGYG000001757_01274;MGYG000002234_01026;MGYG000001606_01669;MGYG000000032_01232;MGYG000002105_00002;MGYG000001359_01254;MGYG000002224_01123;MGYG000002438_02321;MGYG000000036_01380;MGYG000001346_01533;MGYG000002136_02858;MGYG000000262_00030;MGYG000003497_00215;MGYG000004754_01565;MGYG000001412_04734;MGYG000002772_01895;MGYG000003921_01124;MGYG000002052_00232;MGYG000002418_00753;MGYG000001615_01716;MGYG000002695_01057;MGYG000000016_02519;MGYG000002279_01932;MGYG000000138_00665;MGYG000001756_00183;MGYG000000201_03875;MGYG000004547_01366;MGYG000003063_00662;MGYG000000271_03365;MGYG000000867_00556;MGYG000000185_02848;MGYG000001315_01207;MGYG000001602_02247;MGYG000001503_00139;MGYG000001405_04470;MGYG000001310_01963;MGYG000003273_00234;MGYG000000140_01590;MGYG000001065_02730;MGYG000003546_00955;MGYG000000022_02283;MGYG000002470_01245;MGYG000002528_01098;MGYG000003446_00658;MGYG000004680_02443;MGYG000002609_01147;MGYG000001436_02249;MGYG000000263_00836;MGYG000003899_01642;MGYG000003891_00382;MGYG000000179_00920;MGYG000003583_01411;MGYG000001749_02490;MGYG000001779_00600;MGYG000000177_01044;MGYG000002290_01325;MGYG000001531_00906;MGYG000001607_01045;MGYG000001141_02439;MGYG000003166_01350;MGYG000004499_02319;MGYG000000251_00064;MGYG000000233_00807;MGYG000000142_00171;MGYG000002702_01978;MGYG000002912_01340;MGYG000001528_00736;MGYG000000236_01807;MGYG000004087_00551;MGYG000001439_02427;MGYG000003701_03123;MGYG000000242_00282;MGYG000000084_02000;MGYG000002417_01244;MGYG000000028_00215;MGYG000000187_02029;MGYG000002641_00069;MGYG000000733_01034;MGYG000001698_04050;MGYG000000212_03313;MGYG000004558_00415;MGYG000003074_01359;MGYG000003185_01053;MGYG000002837_02416;MGYG000000193_02083;MGYG000002272_01482;MGYG000002212_00196;MGYG000000249_00026;MGYG000003236_02455;MGYG000001780_03476;MGYG000001665_01696;MGYG000004630_01824;MGYG000001814_01592;MGYG000003656_01823;MGYG000003504_00096;MGYG000000405_00711;MGYG000001617_01406;MGYG000003001_00359;MGYG000002596_02296;MGYG000001732_00030;MGYG000000206_00901;MGYG000004733_01211 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.23684210526315788 186801|Clostridia 0.7828947368421053 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9539473684210527 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.9539473684210527 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_02058 0.006578947368421052 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365895 0 0 0 0 366936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262894 0 0 0 0 357671 0 0 0 0 639707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328247 0 0 0 0 322043 0 0 0 0 463460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278388 0 0 0 0 341888 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)LYEELQAR MGYG000001255_00207 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_F|m__MGYG000001255 1.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3WHP7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) 1.0 tyrS 1.0 - 1.0 6.1.1.1 1.0 ko:K01866 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R02918 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 S4,tRNA-synt_1b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001255_00207 1.0 tyrosine--tRNA ligase. tyrosyl-tRNA synthetase. - ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl- tRNA(Tyr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01866:YARS, tyrS; tyrosyl-tRNA synthetase [EC:6.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)NAPAQAK MGYG000000099_02570 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000099_02570 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1428231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)NDIALLK MGYG000004158_00685;MGYG000004610_00323;MGYG000000267_01056;MGYG000002492_02947;MGYG000000258_00842;MGYG000000273_02707 domain d__Bacteria 1.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,3VNSJ@526524|Erysipelotrichia 0.3333333333333333 526524|Erysipelotrichia 0.3333333333333333 F 0.3333333333333333 bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain glutamine amidotransferase domain) K01952 0.3333333333333333 - 0.6666666666666666 - 1.0 - 0.6666666666666666 - 0.5 - 0.6666666666666666 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.5 - 1.0 - 1.0 - 1.0 AIRS_C,GATase_5 0.3333333333333333 - 1.0 - 1.0 - 1.0 - 0.8333333333333334 MGYG000004158_00685 0.16666666666666666 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 - 0.6666666666666666 - 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311169 0 0 0 0 218701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5412012 0 0 0 0 0 0 0 0 0 3263679 0 0 4980403 0 0 0 0 5963737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138812405 0 0 0 0 102849188 0 0 0 0 0 0 0 17039024 0 0 0 0 18504308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3735957 0 0 0 0 2900713 0 0 0 0 0 0 0 0 0 0 0 0 155724 0 0 +(Carbamidomethyl)NDLALIK MGYG000003241_00720;MGYG000004158_00685;MGYG000003484_00637 domain d__Bacteria 1.0 COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia,3WHDV@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 0.6666666666666666 KT 0.6666666666666666 Psort location Cytoplasmic, score 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 ko:K02647 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 0.6666666666666666 - 1.0 - 1.0 - 1.0 Diacid_rec,HTH_30 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003241_00720 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02647:cdaR; carbohydrate diacid regulator 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 2945727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5116221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)NLDNISENTSSAESR MGYG000003694_00680;MGYG000001186_01647;MGYG000002517_00135;MGYG000003694_02093 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_00680 0.25 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1597450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)NVWTVAK MGYG000004758_01534;MGYG000001447_02191;MGYG000001770_00014;MGYG000002737_00822;MGYG000001599_00236;MGYG000002540_00128;MGYG000001056_01383;MGYG000002438_03847;MGYG000004823_00968;MGYG000001372_00314;MGYG000001164_00708;MGYG000003542_00145;MGYG000003367_02063;MGYG000002108_01378;MGYG000004464_01891;MGYG000003202_00327;MGYG000000707_01761;MGYG000003469_00859;MGYG000001415_02017;MGYG000002560_03406;MGYG000002603_00629;MGYG000001302.1_00416;MGYG000003697_00528;MGYG000002293_00151;MGYG000000170_01829;MGYG000000243_00245;MGYG000001789_02629;MGYG000002291_01392;MGYG000003279_02296 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0292@1|root,COG0292@2|Bacteria,4NNKU@976|Bacteroidetes,2FSHF@200643|Bacteroidia,4AQX5@815|Bacteroidaceae 0.41379310344827586 976|Bacteroidetes 1.0 J 1.0 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit 1.0 rplT 1.0 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 1.0 - 1.0 ko:K02887 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004758_01534 0.034482758620689655 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02887:RP-L20, MRPL20, rplT; large subunit ribosomal protein L20 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1143317 0 0 0 0 4411191 0 0 0 0 1472958 1420833 0 0 0 0 0 0 0 1792609 0 0 0 0 0 +(Carbamidomethyl)PTFNQLVR MGYG000003494_00688;MGYG000001714_01288;MGYG000002212_02586;MGYG000002707_01737;MGYG000004735_00887;MGYG000000089_01904;MGYG000000383_00775;MGYG000000389_02262;MGYG000000252_01072;MGYG000000099_01237;MGYG000003552_02464;MGYG000003694_02395;MGYG000000262_00027;MGYG000001616_00517;MGYG000002105_00005;MGYG000004842_01773;MGYG000000133_02994;MGYG000002234_01029;MGYG000000141_02555;MGYG000003166_01347;MGYG000004526_00642;MGYG000004482_01538;MGYG000002312_02894;MGYG000001683_01330;MGYG000000145_02778;MGYG000000216_02409;MGYG000002274_00060;MGYG000004879_01611;MGYG000004760_00915;MGYG000002517_00202;MGYG000002651_00010;MGYG000000909_01305;MGYG000002993_01299;MGYG000004296_01665;MGYG000002154_01514;MGYG000002835_01672;MGYG000004785_01483;MGYG000000319_00856;MGYG000001300_00283;MGYG000002670_00361;MGYG000000139_00694;MGYG000001338_03376;MGYG000000150_02016;MGYG000000278_00901;MGYG000004317_00569;MGYG000000050_01746;MGYG000004431_01378;MGYG000000164_01099;MGYG000002702_02230;MGYG000001255_01102;MGYG000002289_02135;MGYG000001757_01271;MGYG000002224_01126;MGYG000000312_01433;MGYG000000724_01269;MGYG000001502_01275;MGYG000000280_01197;MGYG000001247_00855;MGYG000000200_01985;MGYG000000258_00263;MGYG000002057_01069;MGYG000003921_01127;MGYG000002492_00341;MGYG000002067_00670;MGYG000002040_01209;MGYG000000127_03985;MGYG000000369_00924;MGYG000002250_00453;MGYG000004747_01983;MGYG000001199_02552;MGYG000002026_01855;MGYG000002025_02452;MGYG000003510_00299;MGYG000003819_01359;MGYG000000271_03362;MGYG000000515_01912;MGYG000002148_02229;MGYG000001707_01473;MGYG000001315_01204;MGYG000001632_01554;MGYG000000217_01432;MGYG000000206_00898;MGYG000004276_00125;MGYG000002966_00549;MGYG000000325_02385;MGYG000000263_00833;MGYG000000562_01880;MGYG000002945_01967;MGYG000000090_01717;MGYG000003899_01645;MGYG000001157_01849;MGYG000002610_00228;MGYG000000028_00229;MGYG000002965_00481;MGYG000004628_02702;MGYG000004869_02963;MGYG000004726_01619;MGYG000001531_00909;MGYG000003589_00203;MGYG000001027_01013;MGYG000003355_03288;MGYG000000301_02342;MGYG000000119_01820;MGYG000001637_00072;MGYG000000194_01013;MGYG000000213_01897;MGYG000001689_01547;MGYG000000031_00744;MGYG000000204_00535;MGYG000000251_00061;MGYG000003074_01356;MGYG000004271_02228;MGYG000002136_02397;MGYG000002247_00116;MGYG000003684_05129;MGYG000000078_01684;MGYG000002641_00066;MGYG000000242_00285;MGYG000002974_01333;MGYG000002953_03324;MGYG000002417_01247;MGYG000000087_02569;MGYG000002251_01053;MGYG000002837_02419;MGYG000000249_00029;MGYG000000989_00161;MGYG000004039_00486;MGYG000001571_02828;MGYG000000274_01838;MGYG000000184_01004;MGYG000001725_00454;MGYG000001374_01221;MGYG000002115_00734;MGYG000001732_00033 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,21ZYE@1506553|Lachnoclostridium 0.5895522388059702 186801|Clostridia 1.0 J 1.0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit 1.0 rpsL 1.0 - 1.0 - 1.0 ko:K02950 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S12_S23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003494_00688 0.007462686567164179 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02950:RP-S12, MRPS12, rpsL; small subunit ribosomal protein S12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)PTINQLVR MGYG000001514_00036;MGYG000003891_00379;MGYG000003266_00423;MGYG000003352_01409;MGYG000002023_01663;MGYG000002659_01141;MGYG000000557_01073;MGYG000000304_01025;MGYG000001470_03725;MGYG000001086_00480;MGYG000003288_00773;MGYG000002050_01598;MGYG000001384_04564;MGYG000001381_02106;MGYG000000120_01187;MGYG000001410_00771;MGYG000001007_01325;MGYG000001651_00898;MGYG000004653_01146;MGYG000001785_00689;MGYG000000198_01162;MGYG000004565_01263;MGYG000003411_00713;MGYG000002447_00577;MGYG000004780_01212;MGYG000003376_00238;MGYG000000277_00489;MGYG000004540_00956;MGYG000002074_00231;MGYG000004158_01415;MGYG000004788_00776;MGYG000000179_00923;MGYG000000291_01370;MGYG000002315_00744;MGYG000004694_00677;MGYG000001436_02252;MGYG000004594_00890;MGYG000004232_01393;MGYG000003836_00554;MGYG000000269_00800;MGYG000002113_00819;MGYG000001647_00753;MGYG000003449_00702;MGYG000003868_01163;MGYG000002065_00315;MGYG000001991_00380;MGYG000001709_00474;MGYG000001613_01113;MGYG000000188_00929;MGYG000000157_01087;MGYG000002370_00101;MGYG000004647_01364;MGYG000004769_00434;MGYG000003802_01290;MGYG000004681_00045;MGYG000001401_00634;MGYG000001740_00096;MGYG000003441_00071;MGYG000004138_00061;MGYG000003369_00138;MGYG000003391_01660;MGYG000001636_01144;MGYG000002972_00644;MGYG000003324_01495;MGYG000003274_01510;MGYG000001460_03660;MGYG000000182_00588;MGYG000002820_00495;MGYG000003482_02072;MGYG000003170_00045;MGYG000001739_00822;MGYG000004704_00524;MGYG000004606_00606;MGYG000003501_00913;MGYG000004804_01398;MGYG000004728_00755;MGYG000001248_01380;MGYG000000045_02619;MGYG000003512_00649;MGYG000003022_00738;MGYG000000974_00870;MGYG000002986_00445;MGYG000001167_00880;MGYG000001646_01115;MGYG000001486_02525;MGYG000004532_01349;MGYG000004789_01482;MGYG000002919_00397;MGYG000000435_00533;MGYG000003110_00480;MGYG000001365_00343;MGYG000002101_01412;MGYG000001642_00116;MGYG000000802_00741 domain d__Bacteria 1.0 COG0048@1|root,COG0048@2|Bacteria,2IHUF@201174|Actinobacteria,4CVWP@84998|Coriobacteriia 0.23404255319148937 186801|Clostridia 0.2553191489361702 J 1.0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit 0.9787234042553191 rpsL 0.9893617021276596 - 0.8404255319148937 - 1.0 ko:K02950 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S12_S23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001514_00036 0.010638297872340425 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02950:RP-S12, MRPS12, rpsL; small subunit ribosomal protein S12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)PTIQQLVR MGYG000002549_02929;MGYG000002291_02259;MGYG000002935_01235;MGYG000002470_01234;MGYG000001489_02610;MGYG000001562_01941;MGYG000004720_00748;MGYG000004536_01500;MGYG000002203_01143;MGYG000001789_00134;MGYG000001783_02410;MGYG000000673_01519;MGYG000001302.1_01162;MGYG000004658_00150;MGYG000001211_01231;MGYG000000138_02893;MGYG000000415_00047;MGYG000002478_00803;MGYG000000170_00045;MGYG000000029_02785;MGYG000002205_00902;MGYG000000414_01220;MGYG000000003_00091;MGYG000002560_00232;MGYG000001599_01855;MGYG000004185_01167;MGYG000001370_01691;MGYG000003279_01341;MGYG000003367_01248;MGYG000000111_01719;MGYG000001364_02758;MGYG000002675_00602;MGYG000001666_01977;MGYG000004469_01445;MGYG000003362_01941;MGYG000002281_02279;MGYG000001435_00765;MGYG000001415_01613;MGYG000001306_02656;MGYG000000243_01975;MGYG000001346_01523;MGYG000001461_00400;MGYG000002033_01887;MGYG000002455_03895;MGYG000002561_02171;MGYG000000254_00223;MGYG000001835_01812;MGYG000004756_01928;MGYG000003282_01776;MGYG000000054_03854;MGYG000003542_01353;MGYG000002120_01197;MGYG000003221_01989;MGYG000000273_00410;MGYG000000781_00844;MGYG000001787_02682;MGYG000000357_01295;MGYG000003701_04690;MGYG000003363_02295;MGYG000004479_01436;MGYG000000196_03985;MGYG000003693_00189;MGYG000004468_00433;MGYG000002438_02204;MGYG000003812_01484;MGYG000000042_01095;MGYG000001644_00961;MGYG000000144_01718;MGYG000001433_02272;MGYG000001420_02918;MGYG000001546_01213;MGYG000001337_03893;MGYG000003539_00287;MGYG000001925_01428;MGYG000004754_02254;MGYG000004464_01243;MGYG000003546_00263;MGYG000000098_02006;MGYG000002082_00491;MGYG000003202_00814;MGYG000003312_02995;MGYG000000053_00689 domain d__Bacteria 1.0 COG0048@1|root,COG0048@2|Bacteria,4NM3Y@976|Bacteroidetes,2FRY7@200643|Bacteroidia 0.6951219512195121 976|Bacteroidetes 0.975609756097561 J 1.0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit 1.0 rpsL 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 0.975609756097561 - 1.0 ko:K02950 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S12_S23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_02929 0.012195121951219513 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02950:RP-S12, MRPS12, rpsL; small subunit ribosomal protein S12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)QLGITTGAQAK MGYG000000356_01643;MGYG000000389_01367;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000356_01643 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)QLGITTGQQAK MGYG000004271_01770;MGYG000000271_01499 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01770 0.5 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)RAQAPVNKDLVTNEEIAADPVAAAMAK MGYG000002492_00484 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC transporter, solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00484 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K15770:cycB, ganO, mdxE; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2750619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)SFDSIDNAPEEKER MGYG000000042_01421;MGYG000004756_01173;MGYG000000196_03974;MGYG000002905_00001;MGYG000000138_00665;MGYG000001661_02666;MGYG000000053_00908;MGYG000004006_00433;MGYG000002762_01733;MGYG000000074_01773;MGYG000001789_00154;MGYG000000273_00431;MGYG000000054_03933;MGYG000000236_01807;MGYG000003701_03123;MGYG000000098_02017;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000001503_00139;MGYG000002281_02290;MGYG000004474_01617;MGYG000003546_00955;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000003446_00658;MGYG000001552_00984;MGYG000001346_01533;MGYG000000243_01988;MGYG000000013_02251;MGYG000001562_01075;MGYG000000348_00283;MGYG000003279_00951;MGYG000000414_00662;MGYG000001655_02933;MGYG000000044_01721;MGYG000002418_00753;MGYG000000117_01463;MGYG000000168_03211 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.025 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)SIAQQQNTQFK MGYG000000076_01275;MGYG000003694_00879;MGYG000000280_01471;MGYG000000153_01461;MGYG000000136_00900;MGYG000001637_02229;MGYG000000271_02102;MGYG000004271_00233;MGYG000000389_02149;MGYG000001186_01721;MGYG000002492_00659;MGYG000002670_01509;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.6923076923076923 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 0.6923076923076923 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000076_01275 0.07692307692307693 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)SVDSIHKELGHIMWDFVGMGR MGYG000002478_01127 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01127 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)TAELYADAVK MGYG000002966_00074;MGYG000000325_00585;MGYG000000181_00012 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,36ETN@31979|Clostridiaceae 0.3333333333333333 186801|Clostridia 1.0 F 0.6666666666666666 Belongs to the phosphoglycerate kinase family 0.3333333333333333 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002966_00074 0.3333333333333333 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739236 0 0 0 0 0 0 0 1117468 0 0 1127828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2516240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)TAIAIDTIINQK MGYG000003683_01588;MGYG000000636_00623;MGYG000000233_00546;MGYG000001514_01217;MGYG000001292_00312;MGYG000000489_01352;MGYG000003494_01954;MGYG000004757_00191;MGYG000002528_01019;MGYG000001615_03892;MGYG000002459_01436;MGYG000000989_00194;MGYG000000756_00392;MGYG000000271_02345;MGYG000002469_00372;MGYG000004271_01936;MGYG000000205_00317;MGYG000002517_03148;MGYG000001692_03638;MGYG000002492_00114;MGYG000001483_02668;MGYG000001315_02892;MGYG000003684_01754 domain d__Bacteria 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia 0.2608695652173913 186801|Clostridia 0.6086956521739131 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 0.5652173913043478 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 0.9565217391304348 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 0.6086956521739131 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000003683_01588 0.043478260869565216 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 937080 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)TAIAIDTILNQK MGYG000002397_01410;MGYG000000233_00546;MGYG000001292_00312;MGYG000000489_01352;MGYG000004757_00191;MGYG000004879_02137;MGYG000000562_01722;MGYG000004380_00710;MGYG000004158_00763;MGYG000002469_00372;MGYG000002517_03148;MGYG000001692_03638;MGYG000001652_00148;MGYG000000436_01069;MGYG000002940_00217;MGYG000001543_00550;MGYG000003546_00355;MGYG000002171_00080;MGYG000000135_04341;MGYG000002528_01019;MGYG000004830_01573;MGYG000000389_00984;MGYG000000271_02345;MGYG000000243_00489;MGYG000004667_03726;MGYG000002720_00901;MGYG000003683_01588;MGYG000000997_00488;MGYG000004718_00143;MGYG000003494_01954;MGYG000000385_00450;MGYG000004719_00798;MGYG000002459_01436;MGYG000000989_00194;MGYG000000756_00392;MGYG000004271_01936;MGYG000002492_00114;MGYG000001315_02892;MGYG000003411_00811;MGYG000001525_01549;MGYG000001613_01167;MGYG000001314_01471;MGYG000001777_00205;MGYG000001247_01309;MGYG000000095_01030;MGYG000003147_00102;MGYG000001514_01217;MGYG000001436_02789;MGYG000000974_01373;MGYG000002963_00964;MGYG000000205_00317;MGYG000000187_00874 domain d__Bacteria 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia 0.23076923076923078 186801|Clostridia 0.6153846153846154 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 0.5769230769230769 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 0.9423076923076923 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 0.6538461538461539 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000002397_01410 0.019230769230769232 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1149098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)TEEELKDFEPDFVVYNASK MGYG000000146_00711 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea|s__Dorea formicigenerans|m__MGYG000000146 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,27V2Q@189330|Dorea 1.0 186801|Clostridia 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000146_00711 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 881764 0 0 0 0 1024973 0 0 0 0 1132425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212429 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)TGHEDNAVGGAK MGYG000000013_03050 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp902362375|m__MGYG000000013 1.0 COG0702@1|root,COG0702@2|Bacteria,4NHVQ@976|Bacteroidetes,2FPT0@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 GM 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_03050 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 774361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)TGLLVDGK MGYG000002961_01417;MGYG000003266_00768 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CUNU@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 Belongs to the pyruvate kinase family 1.0 pyk 1.0 - 1.0 2.7.1.40 1.0 ko:K00873 1.0 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050 1.0 R00200,R00430,R01138,R01858,R02320 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 PK,PK_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002961_01417 0.5 pyruvate kinase. phosphoenol transphosphorylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Purine metabolism|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|Glucagon signaling pathway|Type II diabetes mellitus|Human papillomavirus infection|Viral carcinogenesis|Central carbon metabolism in cancer 1.0 K00873:PK, pyk; pyruvate kinase [EC:2.7.1.40] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1576117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 186786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)VAGNAAVDFANIDKAPEERER MGYG000000271_03365 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_03365 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)VFDEFPK MGYG000002549_04148 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,4AP35@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tat pathway signal sequence domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal 1.0 - 1.0 GH109 1.0 - 1.0 - 1.0 MGYG000002549_04148 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1896906 0 0 0 0 0 0 0 0 0 0 1426036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1194166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)VGFQGVTADQAK MGYG000001338_02545;MGYG000000216_01309;MGYG000000301_01010;MGYG000001689_01427;MGYG000000123_03112;MGYG000000031_02179;MGYG000000200_02457;MGYG000002312_02076;MGYG000000142_01977;MGYG000000213_00371;MGYG000000249_01354 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3XYGS@572511|Blautia 0.5454545454545454 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02545 0.09090909090909091 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)VLVFAK MGYG000000139_00679;MGYG000000217_01483;MGYG000000095_03286;MGYG000002963_02025;MGYG000001698_00708;MGYG000004839_01328;MGYG000000171_01515;MGYG000003694_02390;MGYG000002193_01562;MGYG000004475_01000;MGYG000003391_01004;MGYG000004762_01114;MGYG000002997_00961;MGYG000000201_02339;MGYG000004733_01323;MGYG000001027_00236;MGYG000000771_00908;MGYG000003695_01274;MGYG000002143_01055;MGYG000003142_01874;MGYG000000028_00271;MGYG000002882_00267;MGYG000000119_02509;MGYG000004487_00621;MGYG000000076_03547;MGYG000002966_01277;MGYG000002042_00904;MGYG000000251_00050;MGYG000004296_01660;MGYG000001338_03534;MGYG000000387_00298;MGYG000000154_02173;MGYG000004634_00431;MGYG000001970_02771;MGYG000000212_02414;MGYG000002552_01596;MGYG000004804_00955;MGYG000003425_04472;MGYG000001186_01608;MGYG000001714_01227;MGYG000004735_02574;MGYG000000226_01968;MGYG000000118_00315;MGYG000004630_01085;MGYG000002116_01221;MGYG000001191_01912;MGYG000002517_00192;MGYG000002944_00189;MGYG000002098_01611;MGYG000003868_01138;MGYG000000477_00308;MGYG000002286_02461;MGYG000004718_01623;MGYG000004158_00989;MGYG000001748_00537;MGYG000002954_00928;MGYG000000271_03296;MGYG000004380_01359;MGYG000000031_00709;MGYG000000262_02173;MGYG000003155_01392;MGYG000000153_01114;MGYG000002213_01020;MGYG000002926_01369;MGYG000004769_00417;MGYG000004714_00474;MGYG000000136_02022;MGYG000001689_01643;MGYG000002057_01279;MGYG000003335_00786;MGYG000000099_00104;MGYG000004702_00047;MGYG000002492_00336;MGYG000004519_00684;MGYG000000982_00331;MGYG000004717_00220;MGYG000001319_01772;MGYG000002298_02666;MGYG000000287_00086;MGYG000001658_02414;MGYG000000078_01689;MGYG000000323_00858;MGYG000003149_00722;MGYG000002670_00356;MGYG000004715_01765;MGYG000000002_03534;MGYG000000364_02037;MGYG000000171_02775;MGYG000001511_00104;MGYG000001660_01137;MGYG000001683_01776;MGYG000004747_01843;MGYG000001651_00889;MGYG000004831_00027;MGYG000000080_02021;MGYG000003702_00729;MGYG000000335_01427;MGYG000003589_00447;MGYG000003116_00418;MGYG000002312_03039;MGYG000000142_01261;MGYG000000562_01874;MGYG000002836_02018;MGYG000001616_00691;MGYG000000187_02021;MGYG000002090_00047;MGYG000002528_01114;MGYG000002707_01484;MGYG000000489_01684;MGYG000003819_01780;MGYG000002835_01623;MGYG000000018_02173;MGYG000000140_01578;MGYG000000071_00478;MGYG000000200_03209;MGYG000002072_00516;MGYG000001141_02451;MGYG000003215_01171;MGYG000004359_00731;MGYG000001637_00078;MGYG000004276_00634;MGYG000000252_00576 domain d__Bacteria 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 0.21311475409836064 186801|Clostridia 0.8770491803278688 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 0.9918032786885246 rplA 0.9918032786885246 - 0.9262295081967213 - 0.9918032786885246 ko:K02863 0.9918032786885246 ko03010,map03010 0.9918032786885246 M00178,M00179 0.9918032786885246 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.9918032786885246 - 1.0 - 1.0 - 1.0 Ribosomal_L1 0.9918032786885246 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000139_00679 0.00819672131147541 - - - - 0.9918032786885246 0.9918032786885246 0.9918032786885246 0.9918032786885246 Ribosome 0.9918032786885246 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 0.9918032786885246 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)VQEVLQR MGYG000002485_02059 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0055@1|root,COG0055@2|Bacteria,3794W@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 - 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 MGYG000002485_02059 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02112:ATPF1B, atpD; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)VSAADANVINEDGTR MGYG000000802_00744;MGYG000003266_00420;MGYG000002968_00677;MGYG000002961_00370;MGYG000000188_00926;MGYG000002947_00119;MGYG000003122_00562 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CUED@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000000802_00744 0.14285714285714285 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)VVAELMPYSGGLKR MGYG000000038_01496;MGYG000002298_00537;MGYG000000233_00988;MGYG000000274_03211;MGYG000001687_01701;MGYG000004733_00602;MGYG000001619_01504;MGYG000000404_00181;MGYG000000171_00188;MGYG000000255_01680;MGYG000002934_01839;MGYG000000271_03443;MGYG000000164_01751;MGYG000000489_01565;MGYG000000233_01586;MGYG000001627_02088;MGYG000001311_02982;MGYG000002517_00256;MGYG000001186_01772;MGYG000000489_00239;MGYG000000154_01591;MGYG000002517_00472;MGYG000001714_00944;MGYG000000121_01384;MGYG000000146_03224;MGYG000000150_04584;MGYG000003695_00823;MGYG000000076_01006;MGYG000000245_01075;MGYG000000249_02125;MGYG000004799_01118;MGYG000000179_02174;MGYG000002279_02523;MGYG000001315_01115;MGYG000004271_01229;MGYG000000087_01969;MGYG000000198_04021;MGYG000000212_00379 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,27UZQ@189330|Dorea 0.34210526315789475 186801|Clostridia 0.9736842105263158 C 0.9736842105263158 FAD dependent oxidoreductase 0.4473684210526316 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_oxidored,Pyr_redox_2,Pyr_redox_3 0.8421052631578947 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_01496 0.02631578947368421 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)VVTAFVDGWAK MGYG000001300_01498;MGYG000003899_02162;MGYG000002545_02469;MGYG000003291_00077 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 0.5 MGYG000001300_01498 0.25 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 200286 0 0 0 0 307792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 707244 0 0 0 743200 702095 0 0 0 0 0 0 0 0 0 1259976 0 0 625329 0 0 0 0 0 0 0 0 0 0 0 613047 0 0 858020 0 0 0 0 83401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170463 0 0 0 0 1327094 0 0 0 0 161484 0 0 0 0 96749 0 0 0 0 0 +(Carbamidomethyl)YFSVASGGGTGR MGYG000000942_00243;MGYG000003420_01320;MGYG000001658_01116;MGYG000002854_01085;MGYG000004735_00009;MGYG000002802_02025;MGYG000003821_01383;MGYG000000205_02543;MGYG000000802_00613;MGYG000003570_02445;MGYG000004762_01356;MGYG000004517_01958;MGYG000000251_02115;MGYG000002159_02251;MGYG000001925_01569;MGYG000001346_01121;MGYG000000215_01600;MGYG000001871_01775;MGYG000004732_00759;MGYG000004276_01664;MGYG000003160_00232;MGYG000000273_02192;MGYG000003221_02162;MGYG000004604_01207;MGYG000000133_00506;MGYG000001698_03439;MGYG000003474_00100;MGYG000002312_00914;MGYG000002275_01873;MGYG000000515_00648;MGYG000000032_06095;MGYG000000036_01924;MGYG000000258_00155;MGYG000001770_01218;MGYG000002492_01963;MGYG000003450_00728;MGYG000004464_00921;MGYG000002213_00389;MGYG000001615_01983;MGYG000000268_00554;MGYG000000562_01148;MGYG000004779_02234;MGYG000000433_01203;MGYG000000249_02372;MGYG000003446_01092;MGYG000003872_00869;MGYG000004019_01333;MGYG000000223_01510;MGYG000003425_04615;MGYG000001970_01269;MGYG000001786_00203;MGYG000000118_02684;MGYG000000028_01055;MGYG000001027_01414;MGYG000002974_01622;MGYG000001338_01296;MGYG000000263_01515;MGYG000001606_02183;MGYG000004824_01069;MGYG000004055_00746;MGYG000001797_00319;MGYG000002194_01220;MGYG000002444_01680;MGYG000001400_01185;MGYG000002517_01686;MGYG000000212_00326;MGYG000002025_00960;MGYG000001560_01190;MGYG000000245_00061;MGYG000001496_01287;MGYG000001247_02016;MGYG000003012_02646;MGYG000003215_01743;MGYG000000479_02090;MGYG000001806_00888;MGYG000002919_01068;MGYG000002947_01620;MGYG000002880_00963;MGYG000003937_01695;MGYG000000018_02387;MGYG000002293_01605;MGYG000000301_00647;MGYG000003922_03053;MGYG000003693_01584;MGYG000002603_00277;MGYG000002965_01778;MGYG000000378_01853;MGYG000004594_01436;MGYG000002834_01893;MGYG000002438_03055;MGYG000004729_00222;MGYG000003241_01405;MGYG000000312_02568;MGYG000004185_01308;MGYG000000002_01850;MGYG000001636_01063;MGYG000001599_00424;MGYG000000707_02290;MGYG000001319_02415;MGYG000001760_00836;MGYG000004869_01776;MGYG000000391_01131;MGYG000000392_01121;MGYG000002050_01700;MGYG000000013_02686;MGYG000001619_00078;MGYG000004047_01253;MGYG000000387_01305;MGYG000001627_00963;MGYG000000154_00787;MGYG000004630_01662;MGYG000002582_01129;MGYG000003891_01818;MGYG000004561_02010;MGYG000000280_02029;MGYG000004763_01967;MGYG000004493_00376;MGYG000000233_02118;MGYG000004797_02907;MGYG000000140_00469;MGYG000000089_00653;MGYG000000404_00348;MGYG000004733_02764;MGYG000000242_02797;MGYG000004482_01421;MGYG000003470_00018;MGYG000000127_05084;MGYG000004699_02799;MGYG000001415_02505;MGYG000001303_02421;MGYG000002528_00119;MGYG000000136_01348;MGYG000001654_02223;MGYG000002218_00562;MGYG000001604_01691;MGYG000001577_02122;MGYG000001310_00612;MGYG000004140_00114;MGYG000000029_00187;MGYG000001378_03489;MGYG000000045_01847;MGYG000002281_03938;MGYG000000080_01714;MGYG000002098_00644;MGYG000000200_01506;MGYG000000031_02290;MGYG000000142_02731;MGYG000003266_00106;MGYG000000038_01050;MGYG000001300_02120;MGYG000002274_00309;MGYG000003521_00824;MGYG000000039_01269;MGYG000000347_00819;MGYG000002455_00321;MGYG000000269_00015;MGYG000000217_02528;MGYG000000693_00680;MGYG000002985_01044;MGYG000000781_01514;MGYG000000262_01832;MGYG000000187_00466;MGYG000004822_01055;MGYG000001688_03060;MGYG000000198_05683;MGYG000000078_02433;MGYG000000042_01753;MGYG000000196_00899;MGYG000001881_00612;MGYG000001423_03082;MGYG000002286_00349;MGYG000003504_00791;MGYG000003122_01397;MGYG000003335_02616;MGYG000002148_02635;MGYG000003535_01608;MGYG000002224_01738;MGYG000000043_00846;MGYG000000972_01097;MGYG000003589_01350;MGYG000000179_04738;MGYG000002080_00203;MGYG000003851_01315;MGYG000002139_01005;MGYG000002108_00627;MGYG000001697_00682;MGYG000002530_01285;MGYG000000733_01154;MGYG000003483_01370;MGYG000003457_01216;MGYG000003819_00577;MGYG000001763_00631;MGYG000000374_01026;MGYG000001237_02019;MGYG000000989_03267;MGYG000001618_01635;MGYG000001707_00757;MGYG000004317_00089;MGYG000002478_02896;MGYG000001086_01322;MGYG000001785_00655;MGYG000002807_00819 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.18811881188118812 186801|Clostridia 0.5841584158415841 S 0.9554455445544554 GGGtGRT protein 0.2623762376237624 - 0.8861386138613861 - 1.0 - 0.9554455445544554 - 0.9554455445544554 - 0.9554455445544554 - 0.9554455445544554 - 0.9554455445544554 - 0.9554455445544554 - 0.9554455445544554 - 1.0 - 1.0 - 1.0 GGGtGRT 0.9554455445544554 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000942_00243 0.0049504950495049506 - - - - 0.9554455445544554 0.9554455445544554 0.9554455445544554 0.9554455445544554 - 0.9554455445544554 - 0.9554455445544554 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)YKGILEVTGGR MGYG000000002_00856;MGYG000000301_00189;MGYG000000252_01792;MGYG000000216_02330;MGYG000002298_00361;MGYG000000031_02237;MGYG000001338_02781;MGYG000001496_03147;MGYG000000389_02481;MGYG000004733_01001 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3XYWU@572511|Blautia 0.5 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000002_00856 0.1 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)YNSVEVPTK MGYG000000133_00993;MGYG000000301_01128 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00993 0.5 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471150 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 605542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340675 0 0 628696 0 0 0 936069 0 819342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1012036 0 0 0 0 0 +(Carbamidomethyl)YRPQFYLR MGYG000004757_00594;MGYG000000042_01421;MGYG000000408_01653;MGYG000004464_00178;MGYG000000138_00665;MGYG000000385_01364;MGYG000000053_00908;MGYG000001630_01142;MGYG000003643_00595;MGYG000004006_00433;MGYG000004848_00666;MGYG000003353_00058;MGYG000000074_01773;MGYG000003460_01161;MGYG000000215_00564;MGYG000002219_01207;MGYG000001806_01406;MGYG000001925_01419;MGYG000000273_00431;MGYG000004763_01689;MGYG000003681_02037;MGYG000001302.1_00073;MGYG000003202_00129;MGYG000002281_02290;MGYG000001503_00139;MGYG000000357_02040;MGYG000003546_00955;MGYG000001770_01653;MGYG000003992_01709;MGYG000002470_01245;MGYG000003446_00658;MGYG000001552_00984;MGYG000002165_00803;MGYG000001313_00097;MGYG000004629_00424;MGYG000000013_02251;MGYG000003691_01713;MGYG000003542_01415;MGYG000002455_03884;MGYG000003697_01485;MGYG000000348_00283;MGYG000001655_02933;MGYG000000044_01721;MGYG000001360_01239;MGYG000002834_01866;MGYG000002930_00867;MGYG000003152_01866;MGYG000004756_01173;MGYG000000196_03974;MGYG000004588_00463;MGYG000002905_00001;MGYG000001661_02666;MGYG000003374_00521;MGYG000002762_01733;MGYG000001789_00154;MGYG000000054_03933;MGYG000002293_00521;MGYG000000236_01807;MGYG000003701_03123;MGYG000002291_02272;MGYG000000098_02017;MGYG000000170_00073;MGYG000002080_00527;MGYG000004474_01617;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000001346_01533;MGYG000000243_01988;MGYG000001780_03476;MGYG000001562_01075;MGYG000002540_03367;MGYG000001763_00317;MGYG000000254_02569;MGYG000003812_01875;MGYG000003279_00951;MGYG000003497_00215;MGYG000000414_00662;MGYG000002418_00753;MGYG000000117_01463;MGYG000003535_00219;MGYG000000168_03211;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.32142857142857145 976|Bacteroidetes 0.9166666666666666 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9761904761904762 tuf 1.0 - 0.9761904761904762 - 1.0 ko:K02358 0.9761904761904762 - 0.9761904761904762 - 0.9761904761904762 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9761904761904762 - 0.9761904761904762 - 1.0 - 0.9761904761904762 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004757_00594 0.011904761904761904 - - - - 1.0 1.0 1.0 1.0 - 0.9761904761904762 K02358:tuf, TUFM; elongation factor Tu 0.9761904761904762 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)YVEILNVVK MGYG000000271_02100;MGYG000000489_01027 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02100 0.5 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamidomethyl)YVVMSAPSKDDTPMFVC(Carbamidomethyl)GVNEK MGYG000000196_00479;MGYG000004479_00217;MGYG000003693_00860;MGYG000004464_00783;MGYG000003312_01022;MGYG000001661_02632;MGYG000002455_02200;MGYG000002478_03999;MGYG000001783_01519;MGYG000001313_02393;MGYG000002549_00455;MGYG000000243_01331;MGYG000000273_02725;MGYG000002281_04045;MGYG000000043_01774;MGYG000004748_00450;MGYG000001345_01069;MGYG000003681_00790;MGYG000002933_02039 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00479 0.05263157894736842 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 392825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581766 0 0 0 0 460437 0 0 313698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193945 0 0 0 0 0 0 0 285188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232154 +(Carbamyl)AAASESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1136994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 925080 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)AAATAADKAR MGYG000004733_00775;MGYG000001338_01157;MGYG000000133_00993;MGYG000000301_01128 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_00775 0.25 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4991204 0 0 0 0 0 0 0 0 0 4734591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522778 0 0 0 0 0 0 0 0 0 470067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1377675 0 0 0 0 0 0 0 0 0 1961266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)AAAVNIVPNSTGAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_02459 0.011111111111111112 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 139539 0 0 0 0 0 0 201601 0 0 0 0 0 0 0 0 0 0 232252 0 0 0 0 0 0 0 0 0 0 0 204124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237542 0 424172 0 0 0 0 0 0 157375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 708181 0 0 0 0 0 0 774803 0 0 0 790040 925780 0 0 0 478129 0 578251 0 0 0 0 0 0 0 489559 0 614992 0 1026640 0 0 0 0 556404 +(Carbamyl)AADDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642195 0 0 0 0 0 0 0 0 0 0 0 916507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375070 0 0 0 0 751065 +(Carbamyl)AADIVLQAAIAAGAPK MGYG000002323_02346;MGYG000000093_03243;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206;MGYG000002534_02768;MGYG000003883_03730 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.8571428571428571 1236|Gammaproteobacteria 1.0 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.8571428571428571 adhE 1.0 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_02346 0.14285714285714285 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4990357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)AALIDC(Carbamidomethyl)LAPDR MGYG000002515_01045;MGYG000002535_02741;MGYG000002323_01572;MGYG000002494_01366;MGYG000002507_01860;MGYG000002506_00283;MGYG000000107_04278;MGYG000000235_02283;MGYG000003372_01027 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3WWJT@544|Citrobacter 0.3333333333333333 1236|Gammaproteobacteria 1.0 M 1.0 Belongs to the ompA family 0.3333333333333333 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_01045 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03286:TC.OOP; OmpA-OmpF porin, OOP family 1.0 none 1.0 0 0 264487 0 0 0 0 0 0 76673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 580529 0 0 0 0 0 0 652529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376578 0 0 0 0 359151 0 0 199366 0 0 0 0 0 0 260145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317960 0 0 0 0 310381 0 0 166071 0 0 0 0 0 0 171097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)AAPAVVTPIFQNAGK MGYG000001346_01584 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1256@1|root,COG1256@2|Bacteria,4PKVX@976|Bacteroidetes,2G05N@200643|Bacteroidia,4AWF1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 bacterial-type flagellum assembly 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_01584 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4559138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)ADLKDVEDSNLGLK MGYG000000312_02426;MGYG000003486_02521 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000312_02426 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 327128 0 0 0 0 0 0 0 307489 0 0 0 251276 232738 0 0 0 0 0 168307 0 0 0 0 0 295415 0 0 0 0 0 230573 0 0 0 295368 407596 0 0 0 0 0 0 0 0 0 776199 0 0 0 886938 856895 0 0 0 0 0 1292407 0 0 0 0 0 1158256 0 0 0 0 0 1192677 0 0 0 983091 775402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)AEGALSETHSILQR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00135 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 543017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564671 0 0 0 0 0 0 0 0 0 0 650714 0 0 0 0 0 0 0 0 0 0 0 0 354127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 696152 0 0 0 0 0 0 0 0 0 0 0 0 369377 0 0 0 0 0 0 0 0 0 0 0 0 0 1262660 0 0 0 0 0 0 0 0 0 0 1061280 0 0 0 0 0 0 0 0 0 0 1103462 0 338386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 323315 0 +(Carbamyl)AIGGVIVDGGK MGYG000002517_01802 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 O-acetylhomoserine 1.0 metY 1.0 - 1.0 2.5.1.49 1.0 ko:K01740 1.0 ko00270,ko01100,map00270,map01100 1.0 - 1.0 R01287,R04859 1.0 RC00020,RC02821,RC02848 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01802 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways 1.0 K01740:metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10123944 14223418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)AMVVQHNLTAMNANR MGYG000000404_00502 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA11774|s__UBA11774 sp003507655|m__MGYG000000404 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000404_00502 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)AQAHINAGAR MGYG000000251_00555;MGYG000000280_02459;MGYG000003694_01737;MGYG000002974_01418;MGYG000004140_01100;MGYG000001186_01925;MGYG000000484_01691;MGYG000000398_00286;MGYG000001683_01827;MGYG000001748_01525;MGYG000000271_03250;MGYG000004271_00554;MGYG000001319_00348;MGYG000003828_01578;MGYG000000404_00344;MGYG000002517_01026;MGYG000000153_00303;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000140_01181 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.8095238095238095 186801|Clostridia 1.0 G 0.9047619047619048 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8095238095238095 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_00555 0.047619047619047616 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877738 0 0 0 544619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477472 0 0 0 453505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1794678 0 0 0 1587962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640247 0 0 0 823826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)AQIIAEYGR MGYG000001564_01760;MGYG000000179_05510;MGYG000002946_01744 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,220GG@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 - 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001564_01760 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02956:RP-S15, MRPS15, rpsO; small subunit ribosomal protein S15 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 757454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3668870 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3772603 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)ATEITAYVVK MGYG000004735_01873 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 aconitate hydratase 1.0 ybhJ 1.0 - 1.0 4.2.1.3 1.0 ko:K01681 1.0 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 1.0 M00009,M00010,M00012,M00173,M00740 1.0 R01324,R01325,R01900 1.0 RC00497,RC00498,RC00618 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aconitase,Aconitase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_01873 1.0 aconitate hydratase. citrate hydro-lyase. Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate.-!-The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate.-!-cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate.-!-Formerly EC 4.2.1.4. citrate = D-threo-isocitrate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Glyoxylate and dicarboxylate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K01681:ACO, acnA; aconitate hydratase [EC:4.2.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1202837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769026 0 0 0 0 0 0 0 +(Carbamyl)AVVDAGWMTADHQVGQTGK MGYG000002720_01216 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WCFX@538999|Clostridiales incertae sedis 1.0 186801|Clostridia 1.0 C 1.0 PFAM Electron transfer flavoprotein domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01216 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3061493 0 0 0 0 0 1419834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)AYLEAWDTYK MGYG000004797_03700 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,2FN8P@200643|Bacteroidia,4AMSQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 COG NOG06391 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4301 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_03700 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 969117 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)AYLEAWDTYKEGEK MGYG000004797_03700 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,2FN8P@200643|Bacteroidia,4AMSQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 COG NOG06391 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4301 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_03700 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1351067 0 0 0 0 1368901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95707 0 0 0 0 0 0 0 +(Carbamyl)DVKEEEEFLLR MGYG000000133_00992 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0510@1|root,COG0510@2|Bacteria,1TQW6@1239|Firmicutes,248A0@186801|Clostridia,36UHB@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 M 1.0 Phosphotransferase enzyme family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 APH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00992 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 306280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 906648 0 0 0 0 0 0 0 0 0 998471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)EGMGAFLEKR MGYG000002492_00917;MGYG000002670_01219;MGYG000002953_01330;MGYG000002143_01789;MGYG000003185_01503;MGYG000000099_01614;MGYG000001502_02387;MGYG000002926_00641;MGYG000001564_00906;MGYG000003869_00107;MGYG000004271_02656;MGYG000002673_01999;MGYG000002156_02025;MGYG000000271_02750;MGYG000002517_02338;MGYG000000164_00684;MGYG000003694_02682;MGYG000000489_01666;MGYG000003589_00701;MGYG000000356_02284;MGYG000004276_00459;MGYG000004489_00132 domain d__Bacteria 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.3181818181818182 186801|Clostridia 0.9545454545454546 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5454545454545454 crt 0.9545454545454546 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.045454545454545456 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 217372 0 0 0 0 0 0 471824 0 0 0 0 0 308931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853065 0 0 0 0 0 0 1042894 0 0 0 0 0 1049686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)EHILLAR MGYG000000042_01421;MGYG000004464_00178;MGYG000001673_01975;MGYG000004704_00398;MGYG000000089_01901;MGYG000004288_00862;MGYG000002619_00483;MGYG000000412_01546;MGYG000002259_00929;MGYG000002926_00232;MGYG000000099_01234;MGYG000004763_01689;MGYG000003681_02037;MGYG000001384_04567;MGYG000003937_01027;MGYG000002707_01740;MGYG000002994_01317;MGYG000001313_00097;MGYG000003266_00392;MGYG000002455_03884;MGYG000000348_00283;MGYG000001776_00769;MGYG000000044_01721;MGYG000001672_00396;MGYG000002059_00460;MGYG000002685_01157;MGYG000002557_00102;MGYG000000196_03974;MGYG000001008_02651;MGYG000001661_02666;MGYG000001300_00280;MGYG000004769_00437;MGYG000002084_01252;MGYG000000433_00368;MGYG000003022_00748;MGYG000002040_01212;MGYG000002098_01616;MGYG000003266_00955;MGYG000000098_02017;MGYG000001757_01274;MGYG000001299_01777;MGYG000002224_01123;MGYG000002438_02321;MGYG000000163_00957;MGYG000004285_00597;MGYG000001346_01533;MGYG000003073_01160;MGYG000001616_00520;MGYG000003921_01124;MGYG000001238_02207;MGYG000002996_00986;MGYG000002052_00232;MGYG000002418_00753;MGYG000002448_02351;MGYG000000223_03134;MGYG000003352_00730;MGYG000001319_01764;MGYG000004757_00594;MGYG000001365_00649;MGYG000002695_01057;MGYG000000138_00665;MGYG000004769_00412;MGYG000001630_01142;MGYG000002673_02521;MGYG000003022_00735;MGYG000004717_00227;MGYG000000365_00508;MGYG000004276_00122;MGYG000001925_01419;MGYG000000273_00431;MGYG000000867_00556;MGYG000004788_02115;MGYG000000291_00377;MGYG000003202_00129;MGYG000002993_01302;MGYG000000357_02040;MGYG000002953_03321;MGYG000003546_00955;MGYG000000375_01434;MGYG000000022_02283;MGYG000002901_00528;MGYG000003446_00658;MGYG000003899_01642;MGYG000003891_00382;MGYG000002925_00238;MGYG000003428_00555;MGYG000000490_01981;MGYG000003686_02367;MGYG000001356_01661;MGYG000001655_02933;MGYG000003977_00001;MGYG000003166_01350;MGYG000003170_00035;MGYG000002905_00001;MGYG000002972_00178;MGYG000002098_00731;MGYG000002702_01978;MGYG000002912_01340;MGYG000003424_00456;MGYG000001789_00154;MGYG000001567_01738;MGYG000000182_00585;MGYG000003441_00074;MGYG000000236_01807;MGYG000003701_03123;MGYG000000084_02000;MGYG000002291_02272;MGYG000004642_00846;MGYG000000187_02029;MGYG000002641_00069;MGYG000001500_01929;MGYG000003170_00048;MGYG000000445_01370;MGYG000002272_01482;MGYG000004221_01651;MGYG000000243_01988;MGYG000001780_03476;MGYG000001665_01696;MGYG000003504_00096;MGYG000001421_00009;MGYG000001646_01118;MGYG000004047_00605 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.1721311475409836 186801|Clostridia 0.45081967213114754 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9590163934426229 - 1.0 ko:K02358 0.9836065573770492 - 0.9836065573770492 - 0.9836065573770492 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9836065573770492 - 0.9836065573770492 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.00819672131147541 - - - - 1.0 1.0 1.0 1.0 - 0.9836065573770492 K02358:tuf, TUFM; elongation factor Tu 0.9836065573770492 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1448548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)EHILLSR MGYG000000080_02058;MGYG000000245_03248;MGYG000001688_04229;MGYG000001654_02237;MGYG000004718_00646;MGYG000004735_00884;MGYG000000280_01200;MGYG000004565_01266;MGYG000001714_01291;MGYG000001760_00949;MGYG000000198_01165;MGYG000004893_00932;MGYG000000392_00966;MGYG000003324_00542;MGYG000002563_00522;MGYG000001507_06245;MGYG000000133_02991;MGYG000000919_01815;MGYG000004879_01608;MGYG000001234_01151;MGYG000001623_00993;MGYG000000466_00679;MGYG000000446_00437;MGYG000002202_00030;MGYG000003208_02857;MGYG000002563_00509;MGYG000003895_00135;MGYG000001619_01314;MGYG000000216_02406;MGYG000002517_00205;MGYG000000034_01346;MGYG000000123_01153;MGYG000004296_01668;MGYG000000277_00173;MGYG000004508_00787;MGYG000001469_02077;MGYG000001431_01181;MGYG000001809_00576;MGYG000001652_01300;MGYG000000127_03982;MGYG000000258_00266;MGYG000002670_00364;MGYG000004502_00031;MGYG000004600_00789;MGYG000001635_01137;MGYG000000139_00697;MGYG000001611_00087;MGYG000000255_02009;MGYG000000404_00531;MGYG000000164_01096;MGYG000000018_00453;MGYG000002234_01026;MGYG000000032_01232;MGYG000001777_01732;MGYG000002105_00002;MGYG000000347_00343;MGYG000000532_02409;MGYG000002136_02858;MGYG000003146_01522;MGYG000002286_02469;MGYG000000262_00030;MGYG000001412_04734;MGYG000002772_01895;MGYG000002492_00344;MGYG000003753_00317;MGYG000001615_01716;MGYG000002854_00111;MGYG000001487_02232;MGYG000000143_00646;MGYG000000016_02519;MGYG000002279_01932;MGYG000000201_03875;MGYG000002485_02622;MGYG000004547_01366;MGYG000003063_00662;MGYG000004893_01944;MGYG000000271_03365;MGYG000000185_02848;MGYG000000230_00429;MGYG000001315_01207;MGYG000001602_02247;MGYG000001508_00032;MGYG000001464_00103;MGYG000001558_01002;MGYG000001400_03001;MGYG000001405_04470;MGYG000001310_01963;MGYG000003273_00234;MGYG000000140_01590;MGYG000001404_04883;MGYG000000323_00619;MGYG000001065_02730;MGYG000002528_01098;MGYG000004302_00459;MGYG000004680_02443;MGYG000002609_01147;MGYG000001436_02249;MGYG000000263_00836;MGYG000000157_01091;MGYG000004789_00520;MGYG000000179_00920;MGYG000000134_02651;MGYG000002839_00878;MGYG000000217_01428;MGYG000000173_00405;MGYG000000177_01044;MGYG000001485_02164;MGYG000002290_01325;MGYG000001531_00906;MGYG000002220_00457;MGYG000002195_01684;MGYG000001607_01045;MGYG000000226_00644;MGYG000001141_02439;MGYG000000024_03409;MGYG000003425_03741;MGYG000000251_00064;MGYG000002444_02629;MGYG000000233_00807;MGYG000000142_00171;MGYG000000121_02189;MGYG000001528_00736;MGYG000004087_00551;MGYG000001439_02427;MGYG000000242_00282;MGYG000004216_00603;MGYG000002417_01244;MGYG000002126_00299;MGYG000000335_01138;MGYG000002854_00124;MGYG000001698_04050;MGYG000004558_00415;MGYG000003074_01359;MGYG000000037_01050;MGYG000002837_02416;MGYG000002997_01472;MGYG000000193_02083;MGYG000002212_00196;MGYG000000249_00026;MGYG000003236_02455;MGYG000000121_03149;MGYG000004799_01385;MGYG000000501_01307;MGYG000004630_01824;MGYG000000045_02616;MGYG000001814_01592;MGYG000003656_01823;MGYG000001432_01745;MGYG000003486_01055;MGYG000001617_01406;MGYG000002596_02296;MGYG000001712_00119;MGYG000003620_01283;MGYG000001007_01315;MGYG000003486_01459;MGYG000001732_00030;MGYG000000206_00901;MGYG000004733_01211 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.13924050632911392 186801|Clostridia 0.740506329113924 J 0.9873417721518988 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9810126582278481 tuf 0.9873417721518988 - 0.8164556962025317 - 0.9936708860759493 ko:K02358 0.930379746835443 - 0.9367088607594937 - 0.9430379746835443 - 0.9936708860759493 - 0.9936708860759493 ko00000,ko03012,ko03029,ko04147 0.930379746835443 - 0.9430379746835443 - 0.9936708860759493 - 0.930379746835443 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 0.9873417721518988 - 0.9936708860759493 - 0.9936708860759493 - 0.9936708860759493 - 0.9936708860759493 MGYG000000080_02058 0.006329113924050633 - - - - 0.9936708860759493 0.9936708860759493 0.9936708860759493 0.9936708860759493 - 0.9367088607594937 K02358:tuf, TUFM; elongation factor Tu 0.930379746835443 none 1.0 1001671 0 0 678214 0 1174840 0 0 471197 1373204 962051 1158084 0 996090 1472955 1108713 1067643 0 719873 0 0 1135212 0 480290 1284355 1211184 1165042 0 0 0 0 0 0 0 1168963 0 986595 0 1178516 0 0 1114386 0 423194 0 0 1580158 1652978 1490259 1358007 0 1296186 861342 1143785 1149168 0 1441739 0 0 383063 0 834780 1050537 1172035 1039265 0 0 0 0 0 0 0 1552750 0 1145424 0 1203710 0 0 1441299 0 966861 0 0 909911 1166059 877707 886121 0 1717185 1714857 1341456 1760541 0 622322 0 0 1220484 0 613220 1647433 1409559 1636415 0 0 0 0 0 0 0 1623658 0 950233 0 520874 0 0 1150050 0 645097 0 0 1297321 1150508 930625 921106 0 1024251 1096206 1084879 1389762 0 926238 0 0 475511 0 775985 1065318 1044383 899888 0 0 0 0 0 0 0 1287624 0 1279680 0 1039243 0 0 2280005 0 1602107 0 0 1613781 2258997 1710069 1741105 0 2094640 2396307 1028366 1671132 0 1666911 0 0 908166 0 2014978 1645240 1409960 1777478 0 0 0 0 0 0 0 1905335 0 2068622 0 +(Carbamyl)EHLLLAR MGYG000000408_01653;MGYG000004732_02398;MGYG000000089_01901;MGYG000000362_00956;MGYG000003547_00975;MGYG000002259_00929;MGYG000001754_00089;MGYG000004694_00667;MGYG000003155_00314;MGYG000004763_01689;MGYG000004685_00908;MGYG000001384_04567;MGYG000003937_01027;MGYG000003992_01709;MGYG000002455_03884;MGYG000000348_00283;MGYG000001672_00396;MGYG000002059_00460;MGYG000001008_02651;MGYG000000196_03974;MGYG000004573_00004;MGYG000001434_01407;MGYG000001661_02666;MGYG000001541_00185;MGYG000001300_00280;MGYG000003851_00676;MGYG000004769_00437;MGYG000002084_01252;MGYG000003869_01538;MGYG000002578_00911;MGYG000000433_00368;MGYG000000349_00457;MGYG000002040_01212;MGYG000000054_03933;MGYG000004528_00894;MGYG000002794_01318;MGYG000001606_01669;MGYG000000202_03457;MGYG000003442_01057;MGYG000004474_01617;MGYG000003868_01133;MGYG000001359_01254;MGYG000002224_01123;MGYG000004201_01254;MGYG000000036_01380;MGYG000003410_00864;MGYG000003073_01160;MGYG000001616_00520;MGYG000002052_00232;MGYG000002418_00753;MGYG000000369_00927;MGYG000000223_03134;MGYG000003352_00730;MGYG000001334_00218;MGYG000002447_00587;MGYG000004757_00594;MGYG000001365_00649;MGYG000002116_00788;MGYG000002695_01057;MGYG000001756_00183;MGYG000003819_01356;MGYG000004769_00412;MGYG000000395_01440;MGYG000001524_01606;MGYG000001193_00787;MGYG000004724_00878;MGYG000000802_00776;MGYG000000372_00001;MGYG000000273_00431;MGYG000000291_00377;MGYG000003202_00129;MGYG000002944_02285;MGYG000002281_02290;MGYG000002447_00574;MGYG000002993_01302;MGYG000002953_03321;MGYG000003546_00955;MGYG000000022_02283;MGYG000002470_01245;MGYG000000375_01434;MGYG000002901_00528;MGYG000000090_01714;MGYG000001737_01514;MGYG000003891_00382;MGYG000003428_00555;MGYG000000490_01981;MGYG000003686_02367;MGYG000001784_02227;MGYG000001749_02490;MGYG000002980_01277;MGYG000001779_00600;MGYG000001356_01661;MGYG000000488_00776;MGYG000000479_00469;MGYG000002930_00867;MGYG000004526_00639;MGYG000003166_01350;MGYG000003868_01166;MGYG000001677_00114;MGYG000003170_00035;MGYG000002905_00001;MGYG000001590_00854;MGYG000002098_00731;MGYG000002912_01340;MGYG000002702_01978;MGYG000003424_00456;MGYG000000182_00585;MGYG000003441_00074;MGYG000002143_01659;MGYG000000084_02000;MGYG000002291_02272;MGYG000004642_00846;MGYG000004300_00119;MGYG000001559_00042;MGYG000000945_00137;MGYG000000187_02029;MGYG000003185_01053;MGYG000000420_01950;MGYG000003170_00048;MGYG000000445_01370;MGYG000002272_01482;MGYG000004221_01651;MGYG000001444_01618;MGYG000003516_01606;MGYG000000243_01988;MGYG000001780_03476;MGYG000004657_01190;MGYG000002540_03367;MGYG000000254_02569;MGYG000001646_01118;MGYG000003660_00194;MGYG000002042_00774;MGYG000002970_01555;MGYG000003013_00349;MGYG000003484_00308;MGYG000000117_01463;MGYG000002659_00459;MGYG000000042_01421;MGYG000003096_01037;MGYG000002106_00224;MGYG000004464_00178;MGYG000004704_00398;MGYG000001673_01975;MGYG000000385_01364;MGYG000004288_00862;MGYG000002619_00483;MGYG000000412_01546;MGYG000000930_01271;MGYG000002926_00232;MGYG000002578_00898;MGYG000000099_01234;MGYG000003460_01161;MGYG000003681_02037;MGYG000001739_00819;MGYG000002707_01740;MGYG000003185_01074;MGYG000001444_01634;MGYG000002994_01317;MGYG000002165_00803;MGYG000001313_00097;MGYG000002654_00465;MGYG000003266_00392;MGYG000004119_01204;MGYG000004482_01535;MGYG000001576_02230;MGYG000001824_01594;MGYG000003628_01000;MGYG000001563_01273;MGYG000001776_00769;MGYG000000044_01721;MGYG000003549_00407;MGYG000002685_01157;MGYG000004800_00190;MGYG000002762_01733;MGYG000003022_00748;MGYG000001502_01278;MGYG000002098_01616;MGYG000003266_00955;MGYG000004826_01022;MGYG000000098_02017;MGYG000003274_01474;MGYG000001757_01274;MGYG000001299_01777;MGYG000002950.1_00050;MGYG000002438_02321;MGYG000002556_01332;MGYG000000163_00957;MGYG000000267_01379;MGYG000001346_01533;MGYG000004285_00597;MGYG000000333_00136;MGYG000004196_01067;MGYG000003497_00215;MGYG000002768_00022;MGYG000002057_01066;MGYG000003921_01124;MGYG000001238_02207;MGYG000002996_00986;MGYG000002448_02351;MGYG000004475_00887;MGYG000000168_03211;MGYG000001319_01764;MGYG000001881_00748;MGYG000004847_01222;MGYG000000138_00665;MGYG000001630_01142;MGYG000002673_02521;MGYG000003022_00735;MGYG000003528_02124;MGYG000001516_01186;MGYG000004717_00227;MGYG000004726_01622;MGYG000004276_00122;MGYG000000365_00508;MGYG000001925_01419;MGYG000004788_02115;MGYG000000266_00259;MGYG000001503_00139;MGYG000000449_00614;MGYG000000120_01190;MGYG000003446_00658;MGYG000001552_00984;MGYG000003899_01642;MGYG000000013_02251;MGYG000003583_01411;MGYG000002925_00238;MGYG000001655_02933;MGYG000001991_00383;MGYG000003977_00001;MGYG000003872_01017;MGYG000002972_00178;MGYG000001567_01738;MGYG000001789_00154;MGYG000000236_01807;MGYG000003701_03123;MGYG000003389_01825;MGYG000004694_00680;MGYG000001559_01093;MGYG000002641_00069;MGYG000000733_01034;MGYG000002114_00077;MGYG000001500_01929;MGYG000000370_00784;MGYG000002006_00835;MGYG000000622_01283;MGYG000002720_00092;MGYG000004746_00230;MGYG000001665_01696;MGYG000003504_00096;MGYG000001421_00009;MGYG000002848_00884;MGYG000003001_00359;MGYG000004047_00605;MGYG000000673_00997 life d__Bacteria 0.9961 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.16141732283464566 186801|Clostridia 0.484251968503937 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.952755905511811 - 1.0 ko:K02358 0.984251968503937 - 0.984251968503937 - 0.984251968503937 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.984251968503937 - 0.984251968503937 - 1.0 - 0.9881889763779528 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000408_01653 0.003937007874015748 - - - - 1.0 1.0 1.0 1.0 - 0.984251968503937 K02358:tuf, TUFM; elongation factor Tu 0.984251968503937 none 1.0 946688 0 0 0 0 0 0 0 0 0 780282 0 0 0 0 0 0 807094 0 0 0 0 1186318 0 0 1056596 0 1396189 0 0 0 0 0 0 0 0 335074 0 1119061 0 0 0 0 0 0 0 0 0 1676207 0 0 0 0 0 0 711118 0 0 0 0 990998 0 0 1091439 0 1286885 0 0 0 0 0 0 0 0 1070326 0 573861 0 0 0 0 0 0 0 0 0 910311 0 0 0 0 0 0 825611 0 0 0 0 991480 0 0 620514 0 1540431 0 0 0 0 0 0 0 0 647510 0 415399 0 0 0 0 0 0 0 0 0 1055969 0 0 0 0 0 0 424897 0 0 0 0 614060 0 0 649120 0 834101 0 0 0 0 0 0 0 0 575036 0 900552 0 0 0 0 0 0 0 0 0 1416798 0 0 0 0 0 0 1121405 0 0 0 0 1052090 0 0 932367 0 570259 0 0 0 0 0 0 0 0 1156377 0 +(Carbamyl)EMIFKQMYANGIKDYFVELEQMPDGR MGYG000002438_02512 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,2FX90@200643|Bacteroidia,231YG@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Xylose isomerase-like TIM barrel 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02512 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1165754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)ERCESPILIAEDSPLLSR MGYG000002517_02216 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1TRJU@1239|Firmicutes,24AQW@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 response regulator receiver 1.0 cheV 1.0 - 1.0 2.7.13.3 1.0 ko:K03407,ko:K03415 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW,HATPase_c,Hpt,Response_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02216 1.0 histidine kinase. protein kinase (histidine). This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine).-!-A number of histones can act as acceptor. ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03407:cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]|K03415:cheV; two-component system, chemotaxis family, chemotaxis protein CheV 1.0 none 1.0 199548 0 0 0 0 0 0 0 0 0 0 0 0 0 148691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242053 0 151471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136859 0 0 0 278446 0 0 0 0 0 0 111421 0 270823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273854 0 0 0 0 0 0 0 0 0 0 333033 0 753483 0 0 0 0 0 0 0 0 0 0 0 0 0 888033 0 0 0 0 0 0 0 0 0 0 725386 781413 0 0 607204 0 0 0 536948 760071 648420 795239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)EVYYC(Carbamidomethyl)GDEDDGHAKK MGYG000000233_01872 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG5263@1|root,COG5263@2|Bacteria,1UY86@1239|Firmicutes,24EH1@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Cell wall-binding repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_01872 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1228161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)GAGLTGEKDDKYYQSGK MGYG000000179_05046;MGYG000001311_00301 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_05046 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 192035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 483459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1382425 0 0 0 0 0 0 0 0 0 0 743962 0 +(Carbamyl)GAPEGFVAPVTPGR MGYG000002549_02918;MGYG000002281_02268;MGYG000001345_04706;MGYG000000196_03996;MGYG000000243_01964;MGYG000001346_01512;MGYG000001313_00067;MGYG000001433_02283;MGYG000001378_05020;MGYG000002561_02182;MGYG000002560_00243;MGYG000000054_03865;MGYG000002455_03906;MGYG000000098_01995;MGYG000002478_00792;MGYG000002933_02454;MGYG000001370_01702;MGYG000003312_02984;MGYG000000013_02229 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,2FRZE@200643|Bacteroidia,4AKTM@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs 1.0 rplP 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02878 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_02918 0.05263157894736842 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02878:RP-L16, MRPL16, rplP; large subunit ribosomal protein L16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 611834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1177359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 578024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3322842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)GFTQDDAHLFVR MGYG000003279_02468;MGYG000000074_00697;MGYG000000003_00538 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,2FMAU@200643|Bacteroidia,22U2K@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000003279_02468 0.3333333333333333 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01868:TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1236451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1880747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)GIDKAEIKR MGYG000002291_02272;MGYG000001630_01142;MGYG000000243_01988;MGYG000003691_01713 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002291_02272 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 955682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 685640 0 0 0 0 718572 0 0 242523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178603 0 0 0 0 145458 0 0 1068896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1100357 0 0 101603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114073 0 0 0 0 5570750 0 0 1274364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 624081 0 0 0 0 64583 +(Carbamyl)GITINTSHVEYQTANR MGYG000000042_01421;MGYG000004756_01173;MGYG000001415_02515;MGYG000002438_02321;MGYG000004658_01205;MGYG000000053_00908;MGYG000000243_01988;MGYG000000013_02251;MGYG000004006_00433;MGYG000001562_01075;MGYG000000074_01773;MGYG000001789_00154;MGYG000003279_00951;MGYG000000273_00431;MGYG000001655_02933;MGYG000004763_01689;MGYG000002418_00753;MGYG000002291_02272;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000000168_03211 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 0.47619047619047616 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.047619047619047616 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 445466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)GLVGAIEAADAMVK MGYG000000233_02829;MGYG000001504_03126;MGYG000001623_00764;MGYG000001388_01233;MGYG000003372_02282;MGYG000003355_02432;MGYG000003869_00942;MGYG000004087_00692;MGYG000002534_03148;MGYG000000262_00362;MGYG000001550_01963;MGYG000002506_01475;MGYG000002042_00147;MGYG000000099_00883;MGYG000000205_00403;MGYG000002477_02550;MGYG000000198_03144;MGYG000001065_00275;MGYG000002098_00283;MGYG000003131_01143;MGYG000004894_01424;MGYG000002707_01829;MGYG000001564_03645;MGYG000000093_02682;MGYG000002854_00976;MGYG000001622_00878;MGYG000002953_02106 domain d__Bacteria 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 0.3333333333333333 186801|Clostridia 0.7407407407407407 CQ 1.0 BMC 0.3333333333333333 - 0.9259259259259259 - 1.0 - 1.0 - 0.6296296296296297 - 1.0 - 1.0 - 1.0 - 1.0 - 0.6296296296296297 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02829 0.037037037037037035 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 0.6296296296296297 none 1.0 0 0 0 0 0 0 0 0 0 0 216241 0 0 0 0 0 0 0 170715 0 0 0 0 0 0 0 0 0 0 0 685211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 671179 0 0 0 0 0 0 0 189451 0 0 0 0 0 0 0 0 0 0 0 775883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 964307 0 0 0 0 0 0 0 3450102 0 0 0 0 0 0 0 0 0 0 0 124409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2556208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4967544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5418715 0 0 0 0 0 0 0 +(Carbamyl)GQKVNPHGLR MGYG000001365_00964;MGYG000002965_00664;MGYG000000249_01545;MGYG000004250_01651;MGYG000001367_00355;MGYG000001714_01322;MGYG000004517_00981;MGYG000004271_00022;MGYG000000177_02166;MGYG000001602_00386;MGYG000002953_00597;MGYG000002279_01066;MGYG000000187_01752;MGYG000000278_00919;MGYG000004769_00445;MGYG000001754_00745;MGYG000000362_00706;MGYG000000195_02127;MGYG000002619_02380;MGYG000002517_02867;MGYG000000515_01665;MGYG000001300_02209;MGYG000002298_00334;MGYG000002304_02165;MGYG000000071_01873;MGYG000000217_01260;MGYG000002528_01845;MGYG000002057_00239;MGYG000000140_01889;MGYG000001606_00218;MGYG000000198_04893;MGYG000000089_01490;MGYG000001315_01342;MGYG000002969_00164;MGYG000002312_02271;MGYG000000194_02276;MGYG000004680_02465;MGYG000000141_02175;MGYG000000139_02402;MGYG000004735_01595;MGYG000000262_00152;MGYG000003324_00575;MGYG000000334_01214;MGYG000000028_01616;MGYG000004593_00047;MGYG000004699_00276;MGYG000000050_01178;MGYG000000153_02048;MGYG000002105_00235;MGYG000002036_00649;MGYG000002154_01336;MGYG000003311_01156;MGYG000003876_00398;MGYG000000164_02758;MGYG000000022_02034;MGYG000000463_00749;MGYG000003422_00860;MGYG000000077_02604;MGYG000004558_00370;MGYG000001314_01374;MGYG000004317_00970;MGYG000000271_01067;MGYG000004736_00671;MGYG000000364_01346;MGYG000000146_01045;MGYG000000231_02152;MGYG000001576_02395;MGYG000001619_00828;MGYG000001338_02801;MGYG000004087_00388;MGYG000001626_01890;MGYG000004784_00630;MGYG000002966_02569;MGYG000004726_03510;MGYG000000258_00287;MGYG000003465_00837;MGYG000002290_02018;MGYG000000119_00095;MGYG000001191_00912;MGYG000000080_02261;MGYG000000171_01899;MGYG000004718_00068;MGYG000003215_00869;MGYG000002545_01134;MGYG000002276_00874;MGYG000000145_02795;MGYG000003895_00039;MGYG000003581_01705;MGYG000000245_02644;MGYG000000076_02814;MGYG000003147_00986;MGYG000001439_02149;MGYG000002113_00808;MGYG000000251_01825;MGYG000002159_00254;MGYG000002234_01447;MGYG000004681_01723;MGYG000004022_00110;MGYG000000591_02148;MGYG000002659_00451;MGYG000002492_00381;MGYG000001954_02309;MGYG000004296_00395;MGYG000000002_00876;MGYG000000179_04594;MGYG000004642_00857;MGYG000004727_00011;MGYG000000182_00577;MGYG000000099_02395 domain d__Bacteria 1.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae 0.2018348623853211 186801|Clostridia 0.908256880733945 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 0.9908256880733946 rpsC 0.9908256880733946 - 0.981651376146789 - 1.0 ko:K02982 0.9908256880733946 ko03010,map03010 0.9908256880733946 M00178,M00179 0.9908256880733946 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.9908256880733946 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 0.9908256880733946 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001365_00964 0.009174311926605505 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.9908256880733946 K02982:RP-S3, rpsC; small subunit ribosomal protein S3 0.9908256880733946 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)HVIISAPAGNDLK MGYG000000301_01012;MGYG000003695_01114;MGYG000001338_02547;MGYG000000133_02283;MGYG000004785_01017;MGYG000004296_01958;MGYG000000213_00374;MGYG000000002_02120;MGYG000003012_02911;MGYG000000806_01930;MGYG000003821_01266 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_01012 0.09090909090909091 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 426362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 634166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 612825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)HYAHVDC(Carbamidomethyl)PGHADYVK MGYG000000171_02844;MGYG000000089_01901;MGYG000003547_00975;MGYG000002259_00929;MGYG000004565_01266;MGYG000001714_01291;MGYG000003353_00058;MGYG000000198_01165;MGYG000004893_00932;MGYG000004804_01395;MGYG000002563_00522;MGYG000004763_01689;MGYG000003363_01661;MGYG000001384_04567;MGYG000001234_01151;MGYG000003992_01709;MGYG000002563_00509;MGYG000001619_01314;MGYG000000348_00283;MGYG000001360_01239;MGYG000004296_01668;MGYG000002834_01866;MGYG000003189_01066;MGYG000004508_00787;MGYG000000742_00548;MGYG000001809_00576;MGYG000001008_02651;MGYG000004588_00463;MGYG000004573_00004;MGYG000001434_01407;MGYG000004600_00789;MGYG000003851_00676;MGYG000002578_00911;MGYG000001515_00389;MGYG000000255_02009;MGYG000000404_00531;MGYG000000164_01096;MGYG000000018_00453;MGYG000001606_01669;MGYG000000202_03457;MGYG000002224_01123;MGYG000001692_03322;MGYG000002052_00232;MGYG000002418_00753;MGYG000000223_03134;MGYG000003352_00730;MGYG000000016_02519;MGYG000001756_00183;MGYG000001193_00787;MGYG000004893_01944;MGYG000000074_01773;MGYG000000372_00001;MGYG000000271_03365;MGYG000002535_04656;MGYG000000273_00431;MGYG000000867_00556;MGYG000000410_01314;MGYG000002281_02290;MGYG000001464_00103;MGYG000000022_02283;MGYG000000375_01434;MGYG000002470_01245;MGYG000004302_00459;MGYG000002901_00528;MGYG000004680_02443;MGYG000003891_00382;MGYG000000490_01981;MGYG000001248_00621;MGYG000002839_00878;MGYG000001779_00600;MGYG000001607_01045;MGYG000002930_00867;MGYG000003425_03741;MGYG000002098_00731;MGYG000000142_00171;MGYG000002912_01340;MGYG000000182_00585;MGYG000002291_02272;MGYG000004300_00119;MGYG000004642_00846;MGYG000000170_00073;MGYG000000187_02029;MGYG000001698_04050;MGYG000000445_01370;MGYG000002272_01482;MGYG000000249_00026;MGYG000000243_01988;MGYG000004657_01190;MGYG000000254_02569;MGYG000001646_01118;MGYG000003013_00349;MGYG000003535_00219;MGYG000002659_00459;MGYG000001732_00030;MGYG000000042_01421;MGYG000002106_00224;MGYG000001673_01975;MGYG000004288_00862;MGYG000001654_02237;MGYG000000412_01546;MGYG000004735_00884;MGYG000003460_01161;MGYG000003681_02037;MGYG000001739_00819;MGYG000003184_03610;MGYG000000133_02991;MGYG000000345_02688;MGYG000004879_01608;MGYG000002165_00803;MGYG000002202_00030;MGYG000001313_00097;MGYG000002654_00465;MGYG000004119_01204;MGYG000001776_00769;MGYG000000044_01721;MGYG000000034_01346;MGYG000001469_02077;MGYG000001431_01181;MGYG000003152_01866;MGYG000002685_01157;MGYG000003374_00521;MGYG000004502_00031;MGYG000000139_00697;MGYG000002762_01733;MGYG000002098_01616;MGYG000004826_01022;MGYG000001757_01274;MGYG000000032_01232;MGYG000001777_01732;MGYG000002105_00002;MGYG000002950.1_00050;MGYG000000347_00343;MGYG000001346_01533;MGYG000004285_00597;MGYG000002772_01895;MGYG000002492_00344;MGYG000000414_00662;MGYG000000168_03211;MGYG000000143_00646;MGYG000002279_01932;MGYG000000138_00665;MGYG000000201_03875;MGYG000000053_00908;MGYG000002603_01782;MGYG000002485_02622;MGYG000004547_01366;MGYG000004006_00433;MGYG000004717_00227;MGYG000000365_00508;MGYG000001602_02247;MGYG000001503_00139;MGYG000000120_01190;MGYG000000140_01590;MGYG000001065_02730;MGYG000001436_02249;MGYG000000263_00836;MGYG000003899_01642;MGYG000000013_02251;MGYG000003583_01411;MGYG000002925_00238;MGYG000000177_01044;MGYG000001485_02164;MGYG000002220_00457;MGYG000001531_00906;MGYG000001991_00383;MGYG000003465_01528;MGYG000004756_01173;MGYG000000024_03409;MGYG000002972_00178;MGYG000000121_02189;MGYG000001567_01738;MGYG000001439_02427;MGYG000000242_00282;MGYG000002417_01244;MGYG000002641_00069;MGYG000000733_01034;MGYG000004558_00415;MGYG000003074_01359;MGYG000001515_00877;MGYG000004658_01205;MGYG000000622_01283;MGYG000003236_02455;MGYG000001665_01696;MGYG000004630_01824;MGYG000003504_00096;MGYG000001617_01406;MGYG000003620_01283;MGYG000001007_01315;MGYG000000408_01653;MGYG000001688_04229;MGYG000004718_00646;MGYG000000280_01200;MGYG000003189_00640;MGYG000004694_00667;MGYG000003324_00542;MGYG000003155_00314;MGYG000002219_01207;MGYG000001507_06245;MGYG000004685_00908;MGYG000001302.1_00073;MGYG000000919_01815;MGYG000001623_00993;MGYG000003142_01879;MGYG000003895_00135;MGYG000002455_03884;MGYG000001672_00396;MGYG000003142_01865;MGYG000000127_03982;MGYG000000196_03974;MGYG000001713_03599;MGYG000001661_02666;MGYG000000258_00266;MGYG000002670_00364;MGYG000001541_00185;MGYG000001300_00280;MGYG000004769_00437;MGYG000001611_00087;MGYG000000433_00368;MGYG000000371_01541;MGYG000000349_00457;MGYG000002040_01212;MGYG000000054_03933;MGYG000004528_00894;MGYG000004474_01617;MGYG000004804_00945;MGYG000003868_01133;MGYG000004722_01495;MGYG000000532_02409;MGYG000000036_01380;MGYG000003410_00864;MGYG000001248_01383;MGYG000002286_02469;MGYG000003812_01875;MGYG000001412_04734;MGYG000003073_01160;MGYG000002937_00892;MGYG000003753_00317;MGYG000002447_00587;MGYG000001365_00649;MGYG000001615_01716;MGYG000002854_00111;MGYG000004769_00412;MGYG000001524_01606;MGYG000003643_00595;MGYG000004724_00878;MGYG000000802_00776;MGYG000000215_00564;MGYG000002515_03208;MGYG000000291_00377;MGYG000003202_00129;MGYG000001508_00032;MGYG000002447_00574;MGYG000002506_02966;MGYG000001310_01963;MGYG000001404_04883;MGYG000003546_00955;MGYG000002528_01098;MGYG000003691_01713;MGYG000000157_01091;MGYG000003394_01668;MGYG000001749_02490;MGYG000000488_00776;MGYG000002195_01684;MGYG000004499_02319;MGYG000003166_01350;MGYG000003868_01166;MGYG000001677_00114;MGYG000003170_00035;MGYG000002905_00001;MGYG000000251_00064;MGYG000000233_00807;MGYG000002514_01953;MGYG000002702_01978;MGYG000003424_00456;MGYG000001528_00736;MGYG000003441_00074;MGYG000002126_00299;MGYG000001559_00042;MGYG000000945_00137;MGYG000002854_00124;MGYG000003185_01053;MGYG000003170_00048;MGYG000004221_01651;MGYG000002212_00196;MGYG000003516_01606;MGYG000004799_01385;MGYG000001780_03476;MGYG000002540_03367;MGYG000001814_01592;MGYG000003656_01823;MGYG000003486_01055;MGYG000003660_00194;MGYG000003514_00785;MGYG000002970_01555;MGYG000001712_00119;MGYG000000117_01463;MGYG000000206_00901;MGYG000004733_01211;MGYG000004464_00178;MGYG000000385_01364;MGYG000000245_03248;MGYG000002619_00483;MGYG000000930_01271;MGYG000002578_00898;MGYG000000392_00966;MGYG000001470_03722;MGYG000001806_01406;MGYG000003185_01074;MGYG000001770_01653;MGYG000000446_00437;MGYG000002994_01317;MGYG000003208_02857;MGYG000004629_00424;MGYG000003542_01415;MGYG000003266_00392;MGYG000000216_02406;MGYG000002364_00543;MGYG000001563_01273;MGYG000002515_03657;MGYG000002517_00205;MGYG000003549_00407;MGYG000001652_01300;MGYG000002557_00102;MGYG000004800_00190;MGYG000001338_03373;MGYG000003022_00748;MGYG000002293_00521;MGYG000000098_02017;MGYG000003274_01474;MGYG000002234_01026;MGYG000002080_00527;MGYG000001299_01777;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000000267_01379;MGYG000000333_00136;MGYG000001562_01075;MGYG000001763_00317;MGYG000000262_00030;MGYG000003279_00951;MGYG000004754_01565;MGYG000002768_00022;MGYG000003921_01124;MGYG000002506_03686;MGYG000001319_01764;MGYG000001881_00748;MGYG000004847_01222;MGYG000001630_01142;MGYG000003063_00662;MGYG000003022_00735;MGYG000003528_02124;MGYG000001925_01419;MGYG000001315_01207;MGYG000000266_00259;MGYG000000449_00614;MGYG000001405_04470;MGYG000003273_00234;MGYG000003446_00658;MGYG000001552_00984;MGYG000002609_01147;MGYG000002514_02415;MGYG000001525_00035;MGYG000000179_00920;MGYG000003697_01485;MGYG000002507_00346;MGYG000000217_01428;MGYG000001655_02933;MGYG000000173_00405;MGYG000002290_01325;MGYG000001141_02439;MGYG000003977_00001;MGYG000003872_01017;MGYG000001789_00154;MGYG000000236_01807;MGYG000004087_00551;MGYG000003701_03123;MGYG000003389_01825;MGYG000004694_00680;MGYG000004216_00603;MGYG000001559_01093;MGYG000000212_03313;MGYG000002830_01189;MGYG000000037_01050;MGYG000002837_02416;MGYG000000193_02083;MGYG000004746_00230;MGYG000000501_01307;MGYG000001421_00009;MGYG000000405_00711;MGYG000001432_01745;MGYG000003001_00359;MGYG000002596_02296;MGYG000004047_00605;MGYG000000673_00997 life d__Bacteria 0.9975 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.09620253164556962 186801|Clostridia 0.47848101265822784 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9645569620253165 tuf 1.0 - 0.9215189873417722 - 1.0 ko:K02358 0.9924050632911392 - 0.9924050632911392 - 0.9924050632911392 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9924050632911392 - 0.9924050632911392 - 1.0 - 0.9493670886075949 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_02844 0.002531645569620253 - - - - 1.0 1.0 1.0 1.0 - 0.9924050632911392 K02358:tuf, TUFM; elongation factor Tu 0.9924050632911392 none 1.0 0 1017916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 547336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 655742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)ICSDNAVFGQPEVGLGITPGFGGTQR MGYG000001315_01870;MGYG000000195_01573;MGYG000001809_02346;MGYG000003937_01091;MGYG000001300_00295;MGYG000003899_01136;MGYG000000022_01324;MGYG000004679_00524;MGYG000003166_01334;MGYG000002274_00044;MGYG000002545_00548;MGYG000004039_00584;MGYG000000217_01338;MGYG000000039_00171;MGYG000002040_01715;MGYG000001255_01114 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 0.75 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.75 thlA 0.75 - 1.0 2.3.1.9 0.75 ko:K00626 0.75 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 0.75 M00088,M00095,M00373,M00374,M00375 0.75 R00238,R01177 0.75 RC00004,RC00326 0.75 ko00000,ko00001,ko00002,ko01000,ko04147 0.75 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01870 0.0625 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 0.75 0.75 0.75 0.75 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 0.75 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3798951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)ICVLEKEEDVC(Carbamidomethyl)C(Carbamidomethyl)GTSK MGYG000000205_00110;MGYG000000038_01495;MGYG000000255_01681 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 1.0 186801|Clostridia 1.0 S 1.0 BFD-like [2Fe-2S] binding domain 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_00110 0.3333333333333333 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 1970668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 970576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)ILVTLLHEMQK MGYG000004525_00228;MGYG000002953_03277;MGYG000002670_01511;MGYG000002727_00924;MGYG000004769_00635;MGYG000003215_01534;MGYG000001356_02661;MGYG000002156_00131;MGYG000002720_01849;MGYG000000164_00683;MGYG000001814_02499;MGYG000001616_02334;MGYG000001637_02269;MGYG000001500_00694;MGYG000004628_02379;MGYG000001711_01126;MGYG000000153_01463;MGYG000003694_00877;MGYG000003589_00853;MGYG000002492_00657;MGYG000002099_02958;MGYG000000204_00804;MGYG000000997_00552;MGYG000000077_02464;MGYG000002926_00108;MGYG000002143_01933;MGYG000000280_01473;MGYG000002485_00796;MGYG000003074_00590;MGYG000002673_02531;MGYG000000389_02151;MGYG000002945_00734;MGYG000000262_02231;MGYG000001793_01810;MGYG000004271_00231;MGYG000000245_02019;MGYG000000271_02104;MGYG000002517_00540;MGYG000004475_01257;MGYG000001315_01871 domain d__Bacteria 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.325 186801|Clostridia 0.925 I 1.0 Belongs to the thiolase family 0.55 thlA 0.925 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004525_00228 0.025 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2885778 0 +(Carbamyl)INHTPDDACVTTFMTPVEK MGYG000001300_00424 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3WGWJ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00424 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4863886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1637147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)IQEKIDWMMNIK MGYG000001313_00346 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_00346 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 628341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)IVTDGCVVSYIHGGGR MGYG000001315_00797 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_00797 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1963218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)LAAIIPIDTAVK MGYG000000182_01809 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Mitsuokella|s__Mitsuokella sp003458855|m__MGYG000000182 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,4H2K7@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000182_01809 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1901992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)LEHTIANLDNVVENTTSAESR MGYG000002552_01183;MGYG000004317_00093;MGYG000000398_01963 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002552_01183 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4586826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)LVAHGVEEVK MGYG000003452_00041 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium ruminantium|m__MGYG000003452 1.0 COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CZ1D@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000003452_00041 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3528315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)MLAHLLK MGYG000000038_02185;MGYG000001311_02933;MGYG000003582_01256;MGYG000001558_01857;MGYG000002619_02023;MGYG000003374_01118;MGYG000000771_01164;MGYG000001412_01313;MGYG000000272_02321;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000001763_00396;MGYG000000223_00996;MGYG000001711_02099;MGYG000004732_01055;MGYG000001255_00370;MGYG000001482_02362;MGYG000001496_01122;MGYG000004493_00097;MGYG000000002_02120;MGYG000002194_02222;MGYG000004271_00554;MGYG000002966_00075;MGYG000004317_00142;MGYG000000233_00345;MGYG000001577_01888;MGYG000000174_02692;MGYG000001652_01009;MGYG000000077_00219;MGYG000000127_04855;MGYG000002993_00787;MGYG000002945_00682;MGYG000000229_00395;MGYG000004610_00503;MGYG000002098_00013;MGYG000002212_00259;MGYG000004826_01307;MGYG000001606_02632;MGYG000000213_00374;MGYG000003465_00706;MGYG000001542_01437;MGYG000002517_01026;MGYG000004707_01697;MGYG000000212_01474;MGYG000002126_00535;MGYG000000515_01608;MGYG000001338_02547;MGYG000003074_01265;MGYG000001493_05257;MGYG000004757_01889;MGYG000002141_01131;MGYG000000217_00275;MGYG000001439_00571;MGYG000000280_02459;MGYG000000249_01352;MGYG000003695_01114;MGYG000004691_00618;MGYG000002641_00563;MGYG000000193_03247;MGYG000000140_01181;MGYG000000080_03115;MGYG000002279_00557;MGYG000004799_00704;MGYG000001814_01253;MGYG000003656_01296;MGYG000000242_02076;MGYG000002492_01379;MGYG000000198_04065;MGYG000001334_01647;MGYG000001199_01005;MGYG000001658_00407;MGYG000001688_03910;MGYG000000278_03657;MGYG000001319_00348;MGYG000000495_01130;MGYG000001303_01883;MGYG000000187_02264;MGYG000003504_01686;MGYG000000371_00136;MGYG000004519_00423;MGYG000000097_00328;MGYG000001525_01747;MGYG000000615_00488;MGYG000001423_00991;MGYG000001157_00577;MGYG000000171_00850;MGYG000000195_01135;MGYG000001008_00728;MGYG000000271_03250;MGYG000000562_01218;MGYG000000022_00437;MGYG000000133_02283;MGYG000002298_02410;MGYG000000489_00503;MGYG000004600_00849;MGYG000000399_00360;MGYG000003694_01737;MGYG000001607_01815;MGYG000000230_01325;MGYG000003355_00996;MGYG000000484_01691;MGYG000001710_00672;MGYG000003001_00320;MGYG000000205_02269;MGYG000000145_03615;MGYG000002528_00367;MGYG000004140_01100;MGYG000002188_01071;MGYG000002286_00420;MGYG000000164_00800;MGYG000001748_01525;MGYG000001714_01796;MGYG000002946_02881;MGYG000000150_00838;MGYG000000404_00344;MGYG000004815_01345;MGYG000000141_02825;MGYG000003552_01242;MGYG000003702_00925;MGYG000001781_01334;MGYG000001542_02015;MGYG000002304_00547;MGYG000004740_01468;MGYG000000045_02136;MGYG000000162_00065;MGYG000000089_01653;MGYG000004296_01958;MGYG000002155_00766;MGYG000000179_02084;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000001299_00204;MGYG000000251_00555;MGYG000002992_00164;MGYG000002974_01418;MGYG000002997_01277;MGYG000001237_01808;MGYG000004785_01017;MGYG000002025_02240;MGYG000002963_04095;MGYG000000463_00862;MGYG000001602_01805;MGYG000002052_00078;MGYG000001970_02077;MGYG000004246_01300;MGYG000000153_00303;MGYG000001315_01699;MGYG000001627_00130;MGYG000001469_02299;MGYG000003409_01628;MGYG000003891_00096;MGYG000001310_02090;MGYG000002445_01920;MGYG000000325_00586;MGYG000000909_00644;MGYG000002234_00398;MGYG000003431_01105;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000004809_00788;MGYG000003450_00202;MGYG000003701_01708;MGYG000001954_02254;MGYG000002638_00362;MGYG000000215_01375;MGYG000001065_01088;MGYG000004810_01402;MGYG000000100_02166;MGYG000002131_02428;MGYG000003335_00316;MGYG000000084_01085;MGYG000001300_02008;MGYG000004866_01631;MGYG000003937_01177;MGYG000000252_01324;MGYG000000365_00999;MGYG000000301_01012;MGYG000004722_00591;MGYG000001186_01925;MGYG000004087_02290;MGYG000000312_01508;MGYG000000204_00778;MGYG000003013_01053;MGYG000002857_01020;MGYG000004288_00401;MGYG000000175_00767;MGYG000004714_00143;MGYG000003133_02653;MGYG000000281_02732;MGYG000001619_01736;MGYG000000398_00286;MGYG000001683_01827;MGYG000001421_02311;MGYG000004789_01485;MGYG000003812_01036;MGYG000004735_01946;MGYG000003503_01071;MGYG000004809_00408;MGYG000004593_01977 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.20398009950248755 186801|Clostridia 0.7711442786069652 C 0.5870646766169154 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.47761194029850745 gap 0.9552238805970149 - 0.9154228855721394 1.2.1.12 0.9850746268656716 ko:K00134 0.9850746268656716 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9850746268656716 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9850746268656716 R01061 0.9850746268656716 RC00149 0.9850746268656716 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9850746268656716 - 0.9950248756218906 - 1.0 - 0.9850746268656716 Gp_dh_C,Gp_dh_N 0.9850746268656716 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_02185 0.004975124378109453 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9850746268656716 0.9850746268656716 0.9850746268656716 0.9850746268656716 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9850746268656716 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9850746268656716 none 1.0 0 523574 0 0 0 587404 0 724559 0 0 531273 0 0 0 0 512826 0 0 0 0 0 487103 0 206307 0 0 0 0 0 0 218098 0 0 0 0 0 0 0 0 737473 0 0 0 324018 0 293019 0 0 491229 0 0 0 0 224458 0 0 0 0 0 209351 0 388567 0 0 0 0 0 0 592476 0 0 0 0 0 0 0 0 752396 0 0 0 393037 0 470008 0 0 341303 0 0 0 0 595050 0 0 0 0 0 598546 0 204260 0 0 0 0 0 0 196385 0 0 0 0 0 0 0 0 439772 0 0 0 285107 0 385070 0 0 387223 0 0 0 0 289846 0 0 0 0 0 313215 0 0 0 0 0 0 0 0 818827 0 0 0 0 0 0 0 0 806772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.1 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 792599 0 669578 0 0 367245 533391 0 640762 691985 591827 0 592139 295684 0 1052401 777319 0 0 0 416376 393229 0 629033 0 324400 0 0 0 681534 0 0 524943 687358 558413 0 441375 443762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81691 0 0 0 0 0 0 0 511771 0 0 0 0 0 0 0 0 0 0 0 0 0 291502 0 0 109035 0 0 165602 721119 0 0 0 596424 0 720687 0 0 993036 0 0 0 0 660802 0 0 0 0 0 0 0 0 745505 0 0 0 0 0 0 0 850361 395928 0 757013 0 0 0 240754 0 0 388027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 452465 1015046 0 1325887 0 0 0 1040931 0 1958577 1833211 1420667 0 953520 1112857 0 979166 1654413 0 1388060 0 1135710 866100 0 1191710 1624915 1354030 0 0 0 2133337 0 0 987641 1437378 1601826 0 3049647 1912001 +(Carbamyl)MYAIIATGGK MGYG000000018_00160;MGYG000002945_00146;MGYG000004140_00663;MGYG000001065_00185;MGYG000001707_00190;MGYG000002963_04167;MGYG000000095_03449;MGYG000002966_01844;MGYG000000141_00422;MGYG000000562_01328;MGYG000001607_00044;MGYG000002609_00091;MGYG000004879_01688;MGYG000002756_01375;MGYG000001543_03463;MGYG000000356_00131;MGYG000001564_03151;MGYG000000136_00836;MGYG000001338_01924;MGYG000004762_02308;MGYG000001687_00102;MGYG000002025_02389;MGYG000000249_01814;MGYG000001688_02554;MGYG000002098_01393;MGYG000001714_01831;MGYG000002445_00346;MGYG000000268_00142;MGYG000000233_01434;MGYG000001602_02315;MGYG000002552_00424;MGYG000000312_00330;MGYG000003684_00524;MGYG000000206_00602;MGYG000000038_02046;MGYG000000171_00402;MGYG000000123_04902;MGYG000004719_01440;MGYG000004735_00428;MGYG000001652_01261;MGYG000001367_01066;MGYG000001496_00976;MGYG000001319_02167;MGYG000004781_02718;MGYG000000262_02346;MGYG000001619_00163;MGYG000000271_00118;MGYG000000087_01675;MGYG000001219_01271;MGYG000002312_01467;MGYG000000164_00669;MGYG000000179_02644;MGYG000004740_00778;MGYG000004630_00782;MGYG000002772_00321;MGYG000004785_01646;MGYG000002145_00595;MGYG000000119_00390;MGYG000000213_03472;MGYG000002835_02344;MGYG000000245_00171;MGYG000000076_01152;MGYG000000080_01568;MGYG000001617_02393;MGYG000003425_04016;MGYG000001814_00334;MGYG000004039_00665;MGYG000001698_00228;MGYG000002247_01198;MGYG000004747_01719;MGYG000000378_00991;MGYG000000205_02464;MGYG000002212_02935;MGYG000002286_00609;MGYG000000193_01220;MGYG000001315_03087;MGYG000000489_00337;MGYG000002670_00617;MGYG000000154_00623;MGYG000001531_02377;MGYG000002992_00061;MGYG000000252_00071;MGYG000000140_00813;MGYG000000806_02097;MGYG000000146_00229;MGYG000002492_01534;MGYG000000187_02418;MGYG000000389_01071;MGYG000002528_02697;MGYG000000142_02633;MGYG000003694_00194;MGYG000004271_00287;MGYG000001493_00431;MGYG000001027_01084;MGYG000000216_01562;MGYG000001379_00307;MGYG000000028_00974;MGYG000001658_02153;MGYG000002279_00674;MGYG000004087_00797;MGYG000000217_01572;MGYG000002517_01481;MGYG000000077_02303;MGYG000000251_01966;MGYG000001310_01505;MGYG000000280_00589;MGYG000001615_00216;MGYG000000194_02994;MGYG000002216_01104;MGYG000002136_00755;MGYG000002170_01844;MGYG000001689_02530;MGYG000000118_00921;MGYG000000359_00548;MGYG000001637_01560;MGYG000000198_03199;MGYG000002234_01697;MGYG000004296_00312 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia 0.2796610169491525 186801|Clostridia 0.9830508474576272 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 - 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000018_00160 0.00847457627118644 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02888:RP-L21, MRPL21, rplU; large subunit ribosomal protein L21 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)NVALDIK MGYG000002274_00818;MGYG000003899_00639;MGYG000000039_01710;MGYG000001255_02108;MGYG000001300_02189;MGYG000002059_00486;MGYG000004866_02020;MGYG000000195_02108;MGYG000000022_02015;MGYG000002619_02361;MGYG000003166_00784;MGYG000002272_00476;MGYG000000084_01028;MGYG000001627_01338;MGYG000003921_00369;MGYG000000573_01503;MGYG000003937_00241;MGYG000001157_00691 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3WJ08@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 - 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_00818 0.05555555555555555 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02952:RP-S13, rpsM; small subunit ribosomal protein S13 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2711393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)SAAELNEELVAAKK MGYG000000038_01584;MGYG000000213_00206;MGYG000000184_01180;MGYG000002945_02576;MGYG000002845_00986;MGYG000001607_01093;MGYG000004733_00976;MGYG000000206_01042;MGYG000001496_03128;MGYG000001748_00602;MGYG000001710_03003;MGYG000001338_02799;MGYG000000200_01105;MGYG000002966_02567;MGYG000000002_00874;MGYG000001698_02694;MGYG000000118_00226;MGYG000000133_00053;MGYG000000301_00168;MGYG000002279_01064 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3Y0MW@572511|Blautia 0.45 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uL29 family 1.0 rpmC 1.0 - 1.0 - 1.0 ko:K02904 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L29 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_01584 0.05 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02904:RP-L29, rpmC; large subunit ribosomal protein L29 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 983980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)SFDSIDNAPEEKER MGYG000000042_01421;MGYG000004756_01173;MGYG000000196_03974;MGYG000002905_00001;MGYG000000138_00665;MGYG000001661_02666;MGYG000000053_00908;MGYG000004006_00433;MGYG000002762_01733;MGYG000000074_01773;MGYG000001789_00154;MGYG000000273_00431;MGYG000000054_03933;MGYG000000236_01807;MGYG000003701_03123;MGYG000000098_02017;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000001503_00139;MGYG000002281_02290;MGYG000004474_01617;MGYG000003546_00955;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000003446_00658;MGYG000001552_00984;MGYG000001346_01533;MGYG000000243_01988;MGYG000000013_02251;MGYG000001562_01075;MGYG000000348_00283;MGYG000003279_00951;MGYG000000414_00662;MGYG000001655_02933;MGYG000000044_01721;MGYG000002418_00753;MGYG000000117_01463;MGYG000000168_03211 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.025 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 821538 0 0 0 0 0 0 0 484071 0 0 724996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690728 0 0 0 0 750945 0 0 458949 0 0 0 0 0 0 0 689308 0 0 390918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342265 0 0 0 0 300620 0 0 473271 0 0 0 0 0 0 0 355978 0 0 406133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326197 0 0 0 0 0 0 0 188292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319441 0 0 0 0 0 0 0 738989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 491247 +(Carbamyl)TCAVSGSGNVAIYAIEK MGYG000002517_02750 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 L 1.0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site 1.0 mfd 1.0 - 1.0 - 1.0 ko:K03723 1.0 ko03420,map03420 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03400 1.0 - 1.0 - 1.0 - 1.0 CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF,UB2H 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02750 1.0 - - - - 1.0 1.0 1.0 1.0 Nucleotide excision repair 1.0 K03723:mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1356880 0 0 0 0 0 0 0 0 0 0 0 0 0 1688679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 673971 0 0 0 0 842775 +(Carbamyl)VAVSALDAAK MGYG000003937_01241 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3WKKU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01241 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02968:RP-S20, rpsT; small subunit ribosomal protein S20 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)VFDIAIHGGK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 0.5 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carbamyl)VVILTGGPDKK MGYG000004271_02656;MGYG000000271_02750;MGYG000000404_01534;MGYG000002517_02338;MGYG000000489_01666;MGYG000000076_01479 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,3NGQJ@46205|Pseudobutyrivibrio 0.6666666666666666 186801|Clostridia 1.0 I 1.0 Enoyl-CoA hydratase/isomerase 0.6666666666666666 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_02656 0.16666666666666666 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 444541 0 0 0 0 0 0 0 0 320506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135079 0 0 0 0 0 0 0 0 906499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1267488 0 0 0 0 0 0 0 0 1125857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)AGVTADSIAK MGYG000002720_01849;MGYG000004487_00561 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,2N6SP@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01849 0.5 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4445872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)ALC(Carbamidomethyl)DTLEGDER MGYG000002223_00163;MGYG000001255_00186;MGYG000002105_01626;MGYG000001300_01405;MGYG000000022_01398 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3WGUG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002223_00163 0.2 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)AVGAEVAKR MGYG000000182_00567 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Mitsuokella|s__Mitsuokella sp003458855|m__MGYG000000182 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4H4PJ@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000182_00567 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 84146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)GIDGHDAASIKR MGYG000002506_02537 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,3XMMK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate 1.0 tktA 1.0 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,ic_1306.c2990 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02537 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 1899373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1230439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2190546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)GVKFDIAKPGESVR MGYG000001315_00847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 28HF7@1|root,2Z7RC@2|Bacteria,1TQET@1239|Firmicutes,249YW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Glycine sarcosine betaine reductase complex, protein B, alpha and beta subunits 1.0 grdE 1.0 - 1.0 1.21.4.2 1.0 ko:K10671 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_00847 1.0 glycine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. 1.0 1.0 1.0 1.0 - 1.0 K10671:grdE; glycine reductase complex component B subunit alpha and beta [EC:1.21.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 197114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635037 0 0 0 0 677369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242270 0 0 0 0 209127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)GVWVFC(Carbamidomethyl)EQR MGYG000002105_00077;MGYG000002610_00221;MGYG000003166_01338;MGYG000000195_01569;MGYG000004487_01101;MGYG000003291_01730;MGYG000002794_00291;MGYG000000022_01320;MGYG000002707_00928;MGYG000001500_03165;MGYG000001824_01146;MGYG000000099_01610;MGYG000002059_01404;MGYG000002224_01329;MGYG000003937_01087;MGYG000004866_01546;MGYG000002651_00003;MGYG000000127_00940;MGYG000002040_01719;MGYG000001761_00373;MGYG000001157_00997;MGYG000003869_00111;MGYG000002619_02235;MGYG000000090_01517;MGYG000001300_00291;MGYG000004732_01392;MGYG000002287_01182;MGYG000002156_02067;MGYG000003899_01132;MGYG000001356_00011;MGYG000002223_00611;MGYG000001255_01110;MGYG000002287_00701;MGYG000004475_01038;MGYG000002720_01216;MGYG000002274_00049;MGYG000003770_01063 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 0.6216216216216216 186801|Clostridia 0.918918918918919 C 1.0 Electron transfer flavoprotein FAD-binding domain 0.6216216216216216 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 0.6216216216216216 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002105_00077 0.02702702702702703 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 566147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 602456 0 0 0 0 638166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)IATELYLKR MGYG000002281_04459;MGYG000004564_00976;MGYG000002807_01339;MGYG000001378_04147;MGYG000003460_00457;MGYG000001780_00270;MGYG000001346_00851;MGYG000003374_01159;MGYG000001164_00399;MGYG000001313_03155;MGYG000001630_01414;MGYG000004699_00382;MGYG000002293_00782;MGYG000003697_00358;MGYG000001991_00556;MGYG000002108_00545;MGYG000004528_00573;MGYG000002935_02197;MGYG000001661_02119;MGYG000001056_00806;MGYG000003794_01885;MGYG000001789_00911;MGYG000000243_00072;MGYG000003521_00114;MGYG000000174_03370;MGYG000004876_01422;MGYG000000707_01912;MGYG000000196_02256;MGYG000001345_03306;MGYG000001489_02767;MGYG000000224_01316;MGYG000003423_01801;MGYG000003351_02552;MGYG000003241_00495;MGYG000003493_02326;MGYG000004561_00777;MGYG000003116_01995;MGYG000004495_00225;MGYG000000054_03589;MGYG000001447_00778;MGYG000004758_02044;MGYG000001925_01382;MGYG000004717_00453;MGYG000002834_01489 domain d__Bacteria 1.0 COG1190@1|root,COG1190@2|Bacteria,4NDZN@976|Bacteroidetes,2FMXC@200643|Bacteroidia,4ANTX@815|Bacteroidaceae 0.38636363636363635 976|Bacteroidetes 0.8181818181818182 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family 1.0 lysS 1.0 - 1.0 6.1.1.6 1.0 ko:K04567 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03658 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DUF4332,tRNA-synt_2,tRNA_anti-codon 0.8181818181818182 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_04459 0.022727272727272728 lysine--tRNA ligase. lysyl-tRNA synthetase. - ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K04567:KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 904126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)IAVDNGGK MGYG000000125_03124 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium_B|s__Clostridium_B tyrobutyricum|m__MGYG000000125 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,36EQT@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000000125_03124 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1813397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)LLAELDENGNTK MGYG000002478_00469;MGYG000000243_00698 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia,4AK9A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 peptidyl-prolyl cis-trans isomerase (trigger factor) 1.0 tig 1.0 - 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00469 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)QGAC(Carbamidomethyl)FSDGTPVTAK MGYG000000233_01508 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,36WU1@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 Extracellular solute-binding protein, family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_01508 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2010619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)QINDAITADIFEHVK MGYG000001255_00900 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_F|m__MGYG000001255 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001255_00900 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)SAWVEYDGNYYFVNSAGAK MGYG000000255_01008 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01008 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3465963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2263093 0 0 0 0 0 0 0 1824957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Carboxymethyl)YVGFGEENQVTADDEAGTITVK MGYG000000562_01218 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp000437735|m__MGYG000000562 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,25VFF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000562_01218 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 881522 0 892057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(CarboxymethylDMAP)TDIPENIK MGYG000001461_00430;MGYG000001489_02640 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,2FMRC@200643|Bacteroidia,4AMR2@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001461_00430 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 0 0 173826 261211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467523 0 0 0 0 0 0 293488 0 0 0 0 0 0 0 0 0 462563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 97820 0 0 0 0 0 319596 0 0 0 0 0 0 529592 0 0 0 0 0 0 0 0 0 616804 0 0 0 0 559487 0 0 0 0 0 0 0 0 0 0 0 0 335359 0 0 500501 0 425005 314436 0 0 0 517985 0 0 0 0 0 0 0 0 0 728744 0 0 0 810074 471034 0 0 0 0 0 0 0 0 0 896017 0 0 1009947 0 0 621041 0 1027293 653367 688451 0 0 824700 0 0 0 0 0 0 0 844246 0 17250335 0 0 0 26202256 20575673 0 0 0 0 0 0 0 0 0 20456502 0 0 25063271 0 0 16291940 0 26070832 19010902 20361243 0 0 18949183 0 0 0 0 0 0 0 25625906 0 +(CarboxymethylDMAP)VQDLEDEVAGLSTR MGYG000000243_01609;MGYG000002171_00452;MGYG000002478_03805 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,2FPGP@200643|Bacteroidia,4ANFP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Zinc ribbon domain protein 1.0 - 1.0 - 1.0 - 1.0 ko:K07164 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 zf-RING_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01609 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07164:K07164; uncharacterized protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 439877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Cytopiloyne+water)ADDAAGLTISEK MGYG000000489_01309;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000002492_03078;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000489_01309 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 887144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1607852 1374321 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Cytopiloyne+water)AEMAATC(Carbamidomethyl)TDPVR MGYG000000262_02730 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02730 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 0 0 0 0 152221 0 0 0 0 0 0 0 0 0 0 0 0 0 431627 0 283631 0 0 0 0 0 0 0 0 0 0 0 0 167497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 601454 0 0 0 0 0 0 0 0 686758 0 0 0 1385058 0 0 0 0 0 0 0 0 0 472262 0 1051358 0 519227 0 0 0 0 0 0 0 0 0 0 2176154 0 0 0 0 0 0 0 0 0 0 0 0 247097 0 0 0 0 0 0 0 0 0 1044857 0 590089 0 1007911 0 0 0 0 0 0 0 0 0 0 872813 0 0 0 0 0 0 0 0 804111 0 0 0 891520 0 0 0 0 0 0 0 0 0 331139 0 0 0 334577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Cytopiloyne+water)ANVALVGTEK MGYG000000142_01601;MGYG000000301_01353;MGYG000001338_00128;MGYG000000216_00449 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01601 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2300562 0 0 2626903 0 0 0 0 0 0 +(Cytopiloyne+water)ASGNIIPSSTGAAK MGYG000002934_01252;MGYG000000196_00479;MGYG000002478_03999;MGYG000003819_01468;MGYG000001783_01519;MGYG000002549_00455;MGYG000001415_02219;MGYG000001789_00244;MGYG000004536_01441;MGYG000000243_01331;MGYG000004006_01717;MGYG000002007_00386;MGYG000000170_00182;MGYG000003202_00946;MGYG000000003_00712 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.4 976|Bacteroidetes 0.8666666666666667 G 0.5333333333333333 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 0.9333333333333333 - 0.9333333333333333 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9333333333333333 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002934_01252 0.06666666666666667 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 10506088 9169411 5944870 0 0 0 0 0 0 8363624 0 0 0 0 0 0 0 5439523 0 6047155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3584607 3167281 2278255 0 0 0 0 0 0 2782553 0 0 0 0 0 0 0 3332704 0 327026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Cytopiloyne+water)LNENDDADETEIK MGYG000000249_00984 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,27I5J@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Peptidase family M20/M25/M40 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_00984 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1047977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Cytopiloyne+water)NAVYPQAELMENVLK MGYG000003921_01192;MGYG000002274_00044;MGYG000001300_00295;MGYG000000039_00171;MGYG000002059_01523;MGYG000003899_01136;MGYG000000022_01324;MGYG000002040_01715;MGYG000001255_01114;MGYG000003166_01334 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_01192 0.1 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Cytopiloyne+water)QLQEIAQTK MGYG000002515_03654 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia fergusonii|m__MGYG000002515 1.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,3ZIPY@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_03654 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02867:RP-L11, MRPL11, rplK; large subunit ribosomal protein L11 1.0 none 1.0 0 0 0 0 0 786149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789145 0 496483 0 0 0 0 0 0 0 0 433848 0 0 0 0 381004 0 0 1838681 0 0 2244461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2127799 0 0 0 0 0 0 640062 0 0 0 662299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Cytopiloyne+water)YILVNTSGK MGYG000000198_04292 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04292 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 470975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146586 0 0 0 0 0 0 459372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352279 0 0 0 0 0 0 0 563542 0 0 0 0 0 304372 0 0 0 0 0 0 274703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 440162 0 0 1258870 0 0 0 0 0 2887171 0 0 0 0 0 0 1677979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603220 0 0 0 0 1989092 +(Dansyl)IAVQNELVAAYNELRDELAQEK MGYG000001313_03232 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia,4AMZ4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 COG NOG14449 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ExbD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_03232 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dehydrated)CGELMMPHR MGYG000000967_00086;MGYG000004781_02148;MGYG000000389_00417;MGYG000001637_01679;MGYG000003828_01159;MGYG000000404_01424;MGYG000002517_01945;MGYG000004891_01821;MGYG000002963_01649;MGYG000004271_01619;MGYG000002131_00197;MGYG000004634_01055;MGYG000000127_02821;MGYG000000271_00778;MGYG000002145_00129;MGYG000000997_00132;MGYG000004210_01966;MGYG000004719_01295;MGYG000001303_02393;MGYG000001683_00880;MGYG000000136_01418;MGYG000002492_01354;MGYG000000245_01688;MGYG000000378_01329;MGYG000001793_00084;MGYG000002974_00298;MGYG000000989_00458;MGYG000002670_00826;MGYG000001027_01111;MGYG000004558_02523;MGYG000001186_01940;MGYG000000489_00567;MGYG000001652_01105 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia 0.45454545454545453 186801|Clostridia 1.0 S 0.7272727272727273 acr, cog1399 0.45454545454545453 - 0.7272727272727273 - 1.0 - 1.0 ko:K07040 0.7272727272727273 - 0.7272727272727273 - 0.7272727272727273 - 1.0 - 1.0 ko00000 0.7272727272727273 - 1.0 - 1.0 - 1.0 DUF177 0.7272727272727273 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000967_00086 0.030303030303030304 - - - - 1.0 1.0 1.0 1.0 - 0.7272727272727273 K07040:yceD, ylbN; DUF177 domain-containing protein 0.7272727272727273 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6262085 0 0 0 0 +(Dehydrated)CVVTGVEMFR MGYG000000215_00564 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella stercorea|m__MGYG000000215 1.0 COG0050@1|root,COG0050@2|Bacteria,4P1C5@976|Bacteroidetes,2FX1Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000215_00564 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 347751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 795995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 929178 0 0 0 0 1197260 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1387491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376035 0 0 0 0 131196 +(Delta_H(2)C(2))AAVEAVK MGYG000002478_01108;MGYG000003510_00246;MGYG000000242_01287;MGYG000001157_00286 domain d__Bacteria 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3WGUG@541000|Ruminococcaceae 0.5 186801|Clostridia 0.75 O 0.5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 0.5 groL 0.5 - 0.5 - 0.75 ko:K04077 0.5 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 0.5 - 1.0 - 0.5 - 0.5 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 0.5 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 0.5 - 1.0 - 1.0 - 1.0 - 0.5 MGYG000002478_01108 0.25 - - - - 0.75 0.75 0.75 0.75 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 0.5 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 0.5 none 1.0 2040145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1565906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Delta_H(2)C(2))EQLVHHDIIDAIENMK MGYG000002494_01934 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,3XNE3@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003872,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005945,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019200,GO:0019318,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035639,GO:0036094,GO:0042802,GO:0042866,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0061615,GO:0061695,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494,GO:1990234 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 iNRG857_1313.NRG857_19550 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01934 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6674351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Delta_H(2)C(2))LSTEQMLPIVDK MGYG000000133_01632 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01632 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 946856 0 0 0 0 0 0 715084 0 0 0 0 0 0 0 0 0 0 705683 0 +(Delta_H(2)C(2))TGLQVR MGYG000002926_00451 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,2N6S2@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000002926_00451 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Delta_H(2)C(2))YLMSQPNMVVAPSK MGYG000000087_01399 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp000435795|m__MGYG000000087 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,222GB@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000087_01399 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2029959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(DiART6plex)FYGNLDAMFDQIHGK MGYG000000243_02236 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,2FN3G@200643|Bacteroidia,4AK6B@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 bifunctional purine biosynthesis protein PurH 1.0 purH 1.0 - 1.0 2.1.2.3,3.5.4.10 1.0 ko:K00602 1.0 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 1.0 M00048 1.0 R01127,R04560 1.0 RC00026,RC00263,RC00456 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 AICARFT_IMPCHas,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02236 1.0 phosphoribosylaminoimidazolecarboxamide formyltransferase. | IMP cyclohydrolase. aminoimidazolecarboxamide ribonucleotide transformylase. | inosinicase. - (6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. | H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. 1.0 1.0 1.0 1.0 Purine metabolism|One carbon pool by folate|Metabolic pathways|Biosynthesis of secondary metabolites|Antifolate resistance 1.0 K00602:purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 3004798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5290560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 674627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(DiART6plex115)VQELSGSDMAHWLK MGYG000002438_02345;MGYG000000243_01742;MGYG000000105_03053;MGYG000002478_02236;MGYG000004797_02345;MGYG000001346_02515 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia,4AKZY@815|Bacteroidaceae 0.8333333333333334 976|Bacteroidetes 1.0 E 1.0 Peptidase C1-like family 0.8333333333333334 pepC 1.0 - 1.0 3.4.22.40 1.0 ko:K01372 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_C1,Peptidase_C1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02345 0.16666666666666666 bleomycin hydrolase. aminopeptidase C (Lactococcus lactis). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain.-!-Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity.-!-Known from bacteria as well as eukaryotic organisms.-!-Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates.-!-Belongs to peptidase family C1. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. 1.0 1.0 1.0 1.0 - 1.0 K01372:BLMH, pepC; bleomycin hydrolase [EC:3.4.22.40] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(DiART6plex118)PLQVETPERPSGQEDVIQLVTPK MGYG000000098_03129 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides bouchesdurhonensis|m__MGYG000000098 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 MGYG000000098_03129 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 192760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264948 0 0 0 0 0 0 0 0 0 0 228658 0 483482 0 0 0 0 0 0 0 0 0 0 0 0 0 851009 0 0 0 0 0 0 0 0 0 0 495878 0 0 0 0 0 0 0 0 0 0 0 0 308639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183825 0 0 0 0 0 0 0 0 0 0 244875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355318 0 0 0 0 0 0 0 0 0 0 0 0 0 232043 0 0 0 0 0 0 0 0 0 0 301123 0 0 0 0 0 0 0 0 0 0 173037 0 +(DiLeu4plex117)LVDDEELIELVEM(Oxidation)EVR MGYG000002997_01472 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Streptococcaceae|g__Lactococcus_A|s__Lactococcus_A piscium_C|m__MGYG000002997 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,42CX2@671232|Streptococcus anginosus group 1.0 91061|Bacilli 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 1.0 - 1.0 ko:K02358,ko:K15771 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002997_01472 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K02358:tuf, TUFM; elongation factor Tu|K15771:ganP, mdxF; arabinogalactan oligomer / maltooligosaccharide transport system permease protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20533998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(DiLeu4plex117)VTDPIADMLTR MGYG000004743_00033 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__RF39|f__UBA660|g__HGM10873|s__HGM10873 sp900753645|m__MGYG000004743 1.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,3VQMK@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit 1.0 rpsH 1.0 - 1.0 - 1.0 ko:K02994 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004743_00033 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02994:RP-S8, MRPS8, rpsH; small subunit ribosomal protein S8 1.0 none 1.0 290192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 637959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361987 0 0 0 0 0 0 0 0 0 0 245835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317692 0 0 0 0 0 0 0 0 0 0 279381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(DiLeu4plex118)TYKAAANATGYDVVLGTSSK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03061 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)AAYFC(Carbamidomethyl)TNDAHTEPLLK MGYG000002720_01439;MGYG000002057_00766 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG1609@1|root,COG1609@2|Bacteria,1TSVS@1239|Firmicutes,24CU2@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 Protein of unknown function (DUF3798) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF3798 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01439 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 3772552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3188201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)AISGYGNVGWGIMK MGYG000002156_01453 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550585|m__MGYG000002156 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002156_01453 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)ALIEAEGDFAR MGYG000000074_02445;MGYG000000003_01106;MGYG000001546_02727;MGYG000001562_02109 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,22U5T@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02445 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)ALNPEHPVLR MGYG000000177_02209;MGYG000003465_01810;MGYG000000036_01152;MGYG000001651_01539;MGYG000004707_01488 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 0.4 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 0.6 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_10,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 0.2 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000177_02209 0.2 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1267052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)ANSAMITPATASPSPR MGYG000000074_02437 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG4770@1|root,COG4770@2|Bacteria,4NSWV@976|Bacteroidetes,2FRYI@200643|Bacteroidia,22UGJ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Biotin-requiring enzyme 1.0 mmdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02437 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2373020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)APAAIGPYSQAK MGYG000000171_01116;MGYG000000213_01248;MGYG000004733_03267;MGYG000002772_01052;MGYG000000200_03694;MGYG000000164_01191;MGYG000000249_02027 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3Y05K@572511|Blautia 0.7142857142857143 186801|Clostridia 1.0 J 1.0 Endoribonuclease L-PSP 0.7142857142857143 - 1.0 - 1.0 3.5.99.10 1.0 ko:K09022 1.0 - 1.0 - 1.0 R11098,R11099 1.0 RC03275,RC03354 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ribonuc_L-PSP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_01116 0.14285714285714285 2-iminobutanoate/2-iminopropanoate deaminase. enamine/imine deaminase. This enzyme, which has been found in all species and tissues examined, catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.-!-The reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates. (1) 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+). (2) 2-iminopropanoate + H2O = NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 - 1.0 K09022:ridA, tdcF, RIDA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)ATVEVTPVLR MGYG000001789_01122;MGYG000002935_01609;MGYG000000243_03128;MGYG000001925_00906;MGYG000002560_00083;MGYG000003693_02255;MGYG000000273_01353;MGYG000000042_01472;MGYG000004797_03123;MGYG000001599_00128;MGYG000002478_01519 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001789_01122 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1408084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)DGLAIIK MGYG000001464_01424 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium|s__Fusobacterium polymorphum|m__MGYG000001464 1.0 COG0015@1|root,COG0015@2|Bacteria,378VV@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 F 1.0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily 1.0 purB 1.0 - 1.0 4.3.2.2 1.0 ko:K01756 1.0 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 1.0 M00048,M00049 1.0 R01083,R04559 1.0 RC00379,RC00444,RC00445 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADSL_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001464_01424 1.0 adenylosuccinate lyase. succino AMP-lyase. Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole. (1) N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate. (2) (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamide + fumarate. 1.0 1.0 1.0 1.0 Purine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01756:purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22317500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)DLKDVEDSNLGLK MGYG000003486_02521 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-95|s__CAG-95 sp000436115|m__MGYG000003486 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003486_02521 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 965827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)EVTNPTR MGYG000000038_01497;MGYG000000233_00987;MGYG000004733_00603;MGYG000000489_00240;MGYG000004271_01230;MGYG000000076_01005;MGYG000000245_01074;MGYG000000404_00182;MGYG000002992_00818;MGYG000000271_03442;MGYG000000164_01750;MGYG000000255_01679;MGYG000000179_02175;MGYG000000198_04020;MGYG000001311_02983;MGYG000001607_00943;MGYG000001315_01116;MGYG000000077_00888;MGYG000002517_00471;MGYG000000262_00169 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,27VRH@189330|Dorea 0.5 186801|Clostridia 1.0 S 1.0 Protein of unknown function (DUF1667) 0.65 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1667,Molybdop_Fe4S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_01497 0.05 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2341813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)FEAATGVK MGYG000000243_00999 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,2FMV2@200643|Bacteroidia,4AMM1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family 1.0 galE 1.0 - 1.0 5.1.3.2 1.0 ko:K01784 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00361,M00362,M00632 1.0 R00291,R02984 1.0 RC00289 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00999 1.0 UDP-glucose 4-epimerase. uridine diphospho-galactose-4-epimerase. Also acts on UDP-2-deoxyglucose. UDP-alpha-D-glucose = UDP-alpha-D-galactose. 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K01784:galE, GALE; UDP-glucose 4-epimerase [EC:5.1.3.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 971385 0 0 0 0 0 0 0 1846077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)FIDAIIKEK MGYG000002515_02505 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia fergusonii|m__MGYG000002515 1.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,3VZ7M@53335|Pantoea 1.0 1236|Gammaproteobacteria 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_02505 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)FSDFNEDGTVK MGYG000002057_00764;MGYG000002036_00786;MGYG000001632_01270;MGYG000001464_00004 domain d__Bacteria 1.0 COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia 0.5 186801|Clostridia 0.75 E 1.0 Beta-eliminating lyase 1.0 tnaA 0.75 - 1.0 4.1.99.1 1.0 ko:K01667 1.0 ko00380,map00380 1.0 - 1.0 R00673 1.0 RC00209,RC00355 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Beta_elim_lyase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002057_00764 0.25 tryptophanase. TNase. The enzyme cleaves a carbon-carbon bond, releasing indole and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-Also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine and other 3-substituted amino acids. H2O + L-tryptophan = indole + NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 Tryptophan metabolism 1.0 K01667:tnaA; tryptophanase [EC:4.1.99.1] 1.0 none 1.0 425431 0 359882 0 0 412754 0 0 371546 0 0 0 0 0 0 0 0 0 0 0 0 382472 0 305456 0 262336 0 0 0 0 0 301987 308958 0 0 236095 339249 258665 2514398 0 1514068 0 0 1915919 0 0 2404903 0 0 0 0 0 0 0 0 0 0 0 0 1620884 0 2430013 0 1987184 0 0 0 0 0 1323760 1372313 0 0 2508322 2384588 1413952 1477797 0 909895 0 0 482484 0 0 995287 0 0 0 0 0 0 0 0 0 0 0 0 1318841 0 619886 0 1125712 0 0 0 0 0 930700 987946 0 0 1027058 1330773 919629 527166 0 471678 0 0 510959 0 0 479380 0 0 0 0 0 0 0 0 0 0 0 0 623627 0 565438 0 400016 0 0 0 0 0 333648 496112 0 0 335250 471539 574628 1088897 0 898457 0 0 654258 0 0 1067562 0 0 0 0 0 0 0 0 0 0 0 0 986678 0 1089485 0 1096670 0 0 0 0 0 1048813 1125872 0 0 1292153 1041789 976160 +(Dicarbamidomethyl)GIIAYFR MGYG000004468_01439 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900539755|m__MGYG000004468 1.0 COG0481@1|root,COG0481@2|Bacteria,4NEJ9@976|Bacteroidetes,2FM9V@200643|Bacteroidia,22UZW@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner 1.0 lepA 1.0 - 1.0 - 1.0 ko:K03596 1.0 ko05134,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000004468_01439 1.0 - - - - 1.0 1.0 1.0 1.0 Legionellosis 1.0 K03596:lepA; GTP-binding protein LepA 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)GISKDVQKGIELAEQLAAALGGGVVGASR MGYG000003166_01338 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539885|m__MGYG000003166 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_01338 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)HVISLQNDR MGYG000000138_04128;MGYG000002218_01634;MGYG000000196_02325;MGYG000002549_04271;MGYG000001345_03406;MGYG000000029_00500;MGYG000001489_00791;MGYG000000355_01655;MGYG000001461_03026;MGYG000000098_00595;MGYG000002438_00804;MGYG000000044_01660 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia,22Y6V@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 U 1.0 Biopolymer transporter ExbD 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ExbD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000138_04128 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 883406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)IAALLASDHVK MGYG000000074_00676 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG4198@1|root,COG4198@2|Bacteria,4NEQC@976|Bacteroidetes,2FPUQ@200643|Bacteroidia,22VDV@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like,SusD-like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00676 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1276927 3213532 0 921618 0 0 1900817 0 0 0 0 2465988 0 0 0 0 1679423 0 1826303 298750 0 0 2040628 0 1961590 0 0 2289407 0 0 1634573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1321491 0 0 0 0 0 0 0 973799 0 0 2078001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1361429 0 0 0 0 0 297389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)IDALIGK MGYG000000074_00389;MGYG000000022_01688 domain d__Bacteria 1.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,2FNBF@200643|Bacteroidia,22U65@171550|Rikenellaceae 0.5 976|Bacteroidetes 0.5 J 0.5 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily 0.5 pheT 0.5 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 0.5 6.1.1.20 0.5 ko:K01890 0.5 ko00970,map00970 0.5 M00359,M00360 0.5 R03660 0.5 RC00055,RC00523 0.5 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 0.5 - 1.0 - 1.0 - 1.0 B3_4,B5,FDX-ACB,tRNA_bind 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00389 0.5 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 0.5 0.5 0.5 0.5 Aminoacyl-tRNA biosynthesis 0.5 K01890:FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2998471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)IGGVIVDGGK MGYG000002517_01802 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 O-acetylhomoserine 1.0 metY 1.0 - 1.0 2.5.1.49 1.0 ko:K01740 1.0 ko00270,ko01100,map00270,map01100 1.0 - 1.0 R01287,R04859 1.0 RC00020,RC02821,RC02848 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01802 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways 1.0 K01740:metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12405133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9257652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)IGTTTGTNGTFSLAAPANGK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01126 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1121580 0 0 0 0 0 0 0 0 0 0 2727640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)LDKESEPDIYNAIKR MGYG000000142_01678;MGYG000002438_01730;MGYG000000184_00227;MGYG000000179_01927;MGYG000000245_00268;MGYG000000146_00711;MGYG000004735_01737;MGYG000000255_01277;MGYG000004763_01642;MGYG000001338_02508;MGYG000001489_01493 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia 0.5454545454545454 186801|Clostridia 0.7272727272727273 H 0.9090909090909091 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 0.7272727272727273 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01678 0.09090909090909091 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1778167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1486439 0 0 3137804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)LEYDLIITGR MGYG000003381_01959 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnoanaerobaculum|s__Lachnoanaerobaculum sp000296385|m__MGYG000003381 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003381_01959 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)LGINAGLINR MGYG000001378_04709 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia,4AMCZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_04709 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1710832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 847384 0 0 0 0 0 0 +(Dicarbamidomethyl)LTGVVVC(Carbamidomethyl)SC(Carbamidomethyl)SPR MGYG000001338_01864;MGYG000000184_02632 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,3Y0ZT@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 4Fe-4S dicluster domain 1.0 - 1.0 - 1.0 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.0 ko:K03388 1.0 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 1.0 M00356,M00357,M00563,M00567 1.0 R04540,R11928,R11931,R11943,R11944 1.0 RC00011 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Fer4,Fer4_10,Fer4_7,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01864 0.5 ferredoxin:CoB-CoM heterodisulfide reductase. | coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase. | H2:CoB-CoM heterodisulfide,ferredoxin reductase. | formate:CoB-CoM heterodisulfide,ferredoxin reductase. - HdrABC is an enzyme complex that is found in most methanogens and catalyzes the reduction of the CoB-CoM heterodisulfide back to CoB and CoM.-!-HdrA contains a FAD cofactor that acts as the entry point for electrons, which are transferred via HdrC to the HdrB catalytic subunit.-!-One form of the enzyme from Methanosarcina acetivorans (HdrA2B2C2) can also catalyze EC 1.8.98.4. cf. EC 1.8.98.5, EC 1.8.98.6, and EC 1.8.98.1. | The enzyme, characterized from the archaeon Methanosarcina acetivorans, catalyzes the reduction of CoB-CoM heterodisulfide back to CoB and CoM.-!-The enzyme consists of three components, HdrA, HdrB and HdrC, all of which contain [4Fe-4S] clusters.-!-Electrons enter at HdrA, which also contains FAD, and are transferred via HdrC to the catalytic component, HdrB.-!-During methanogenesis from acetate the enzyme catalyzes the activity of EC 1.8.7.3.-!-However, it can also use electron bifurcation to direct electron pairs from reduced coenzyme F420 toward the reduction of both ferredoxin and CoB-CoM heterodisulfide.-!-This activity is proposed to take place during Fe(III)-dependent anaerobic methane oxidation. cf. EC 1.8.98.5, EC 1.8.98.6, and EC 1.8.98.1. | This enzyme complex is found in H2-oxidizing CO2-reducing methanogenic archaea such as Methanothermobacter thermautotrophicus.-!-It consists of a cytoplasmic complex of HdrABC reductase and MvhAGD hydrogenase.-!-Electron pairs donated by the hydrogenase are transferred via its Delta subunit to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide.-!-The reductase can also form a similar complex with formate dehydrogenase, see EC 1.8.98.6, formate:CoB-CoM heterodisulfide,ferredoxin reductase. cf. EC 1.8.7.3, EC 1.8.98.4, and EC 1.8.98.1. | The enzyme is found in formate-oxidizing CO2-reducing methanogenic archaea such as Methanococcus maripaludis.-!-It consists of a cytoplasmic complex of HdrABC reductase and formate dehydrogenase.-!-Electron pairs donated by formate dehydrogenase are transferred to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide. cf. EC 1.8.7.3, EC 1.8.98.4, EC 1.8.98.5, and EC 1.8.98.1. coenzyme B + coenzyme M + 2 oxidized [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | coenzyme B + coenzyme M + 4 H(+) + 2 oxidized coenzyme F420-(gamma-L- Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 reduced coenzyme F420-(gamma-L-Glu)(n). | coenzyme B + coenzyme M + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H2 + 2 oxidized [2Fe-2S]- [ferredoxin]. | 2 CO2 + coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]- [ferredoxin]. 1.0 1.0 1.0 1.0 Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03388:hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2785781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)MTGSDFSEITK MGYG000001315_01339;MGYG000001698_02689;MGYG000001338_02804 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,27J0H@186928|unclassified Lachnospiraceae 0.3333333333333333 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01339 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2372884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)MVNVYFFGK MGYG000000184_02627;MGYG000001338_01870 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4656@1|root,COG4656@2|Bacteria,1UY26@1239|Firmicutes,24D3I@186801|Clostridia,3Y0XC@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 2Fe-2S iron-sulfur cluster binding domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer2_4,Fer4_7,Fer4_8,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_02627 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1618293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)MVNVYFFGKK MGYG000000184_02627;MGYG000000142_01107;MGYG000000050_02094;MGYG000001338_01870;MGYG000000216_03378 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia 0.6 186801|Clostridia 1.0 C 1.0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein 0.6 - 1.0 - 1.0 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.6 ko:K03388 0.6 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 0.6 M00356,M00357,M00563,M00567 0.6 R04540,R11928,R11931,R11943,R11944 0.6 RC00011 0.6 ko00000,ko00001,ko00002,ko01000 0.6 - 1.0 - 1.0 - 1.0 FAD_binding_2,Fer4,Fer4_10,Fer4_7,Pyr_redox_2 0.6 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_02627 0.2 ferredoxin:CoB-CoM heterodisulfide reductase. | coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase. | H2:CoB-CoM heterodisulfide,ferredoxin reductase. | formate:CoB-CoM heterodisulfide,ferredoxin reductase. - HdrABC is an enzyme complex that is found in most methanogens and catalyzes the reduction of the CoB-CoM heterodisulfide back to CoB and CoM.-!-HdrA contains a FAD cofactor that acts as the entry point for electrons, which are transferred via HdrC to the HdrB catalytic subunit.-!-One form of the enzyme from Methanosarcina acetivorans (HdrA2B2C2) can also catalyze EC 1.8.98.4. cf. EC 1.8.98.5, EC 1.8.98.6, and EC 1.8.98.1. | The enzyme, characterized from the archaeon Methanosarcina acetivorans, catalyzes the reduction of CoB-CoM heterodisulfide back to CoB and CoM.-!-The enzyme consists of three components, HdrA, HdrB and HdrC, all of which contain [4Fe-4S] clusters.-!-Electrons enter at HdrA, which also contains FAD, and are transferred via HdrC to the catalytic component, HdrB.-!-During methanogenesis from acetate the enzyme catalyzes the activity of EC 1.8.7.3.-!-However, it can also use electron bifurcation to direct electron pairs from reduced coenzyme F420 toward the reduction of both ferredoxin and CoB-CoM heterodisulfide.-!-This activity is proposed to take place during Fe(III)-dependent anaerobic methane oxidation. cf. EC 1.8.98.5, EC 1.8.98.6, and EC 1.8.98.1. | This enzyme complex is found in H2-oxidizing CO2-reducing methanogenic archaea such as Methanothermobacter thermautotrophicus.-!-It consists of a cytoplasmic complex of HdrABC reductase and MvhAGD hydrogenase.-!-Electron pairs donated by the hydrogenase are transferred via its Delta subunit to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide.-!-The reductase can also form a similar complex with formate dehydrogenase, see EC 1.8.98.6, formate:CoB-CoM heterodisulfide,ferredoxin reductase. cf. EC 1.8.7.3, EC 1.8.98.4, and EC 1.8.98.1. | The enzyme is found in formate-oxidizing CO2-reducing methanogenic archaea such as Methanococcus maripaludis.-!-It consists of a cytoplasmic complex of HdrABC reductase and formate dehydrogenase.-!-Electron pairs donated by formate dehydrogenase are transferred to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide. cf. EC 1.8.7.3, EC 1.8.98.4, EC 1.8.98.5, and EC 1.8.98.1. coenzyme B + coenzyme M + 2 oxidized [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | coenzyme B + coenzyme M + 4 H(+) + 2 oxidized coenzyme F420-(gamma-L- Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 reduced coenzyme F420-(gamma-L-Glu)(n). | coenzyme B + coenzyme M + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H2 + 2 oxidized [2Fe-2S]- [ferredoxin]. | 2 CO2 + coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]- [ferredoxin]. 0.6 0.6 0.6 0.6 Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 0.6 K03388:hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] 0.6 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 824017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 829207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.1 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)QNAYVQEMMK MGYG000002478_01632 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4PIVU@976|Bacteroidetes,2FQ1R@200643|Bacteroidia,4APFX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 D 1.0 Domain of unknown function 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01632 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9249365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4836626 5566350 0 0 0 0 0 0 +(Dicarbamidomethyl)SDFSNTTR MGYG000001415_00852;MGYG000004756_00447 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_00852 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1704413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1238088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)TLEEGQK MGYG000000255_00941 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG1278@1|root,COG1278@2|Bacteria 1.0 2|Bacteria 1.0 K 1.0 Cold shock 1.0 cspA 1.0 - 1.0 - 1.0 ko:K03704 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 CSD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_00941 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03704:cspA; cold shock protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3097535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)VAGTGVDIIAAR MGYG000002517_00471 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 protein with conserved CXXC pairs 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1667,Molybdop_Fe4S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00471 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)VIQGMIQGR MGYG000001619_02441;MGYG000000233_01317;MGYG000000205_00610;MGYG000000274_02582;MGYG000000251_01122;MGYG000000194_00522;MGYG000000255_00470;MGYG000000242_00796 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,21ZJJ@1506553|Lachnoclostridium 0.875 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001619_02441 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 2775728 0 0 0 0 0 0 0 0 0 3683838 0 0 2541292 0 0 1261731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2497095 2661222 0 3101111 0 0 0 0 0 3923988 0 0 0 3319639 3278163 0 0 3278433 0 2863424 2370938 0 2244020 0 0 0 0 2936730 2710388 0 2811201 2568586 3085331 0 0 0 0 0 0 0 0 0 0 3672702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2514609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2159535 0 2972432 0 0 0 0 0 0 0 0 3051208 3547370 0 0 2581798 2864586 0 2877632 0 3015279 0 0 0 0 3205471 4019121 0 0 0 0 3665358 0 0 0 2741697 2701842 2457990 0 2841035 0 408642 0 0 0 0 857460 +(Dicarbamidomethyl)VWQVFSAAR MGYG000000089_01082 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000089_01082 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1769586 0 0 0 0 2352183 0 0 0 0 2107430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dicarbamidomethyl)YGVQVIGC(Carbamidomethyl)PK MGYG000003697_01061;MGYG000000042_02105;MGYG000001346_02907;MGYG000002281_01665;MGYG000002834_01170;MGYG000002080_02441;MGYG000002549_01269;MGYG000002960_01607;MGYG000002293_01291;MGYG000001370_00660;MGYG000003363_03107;MGYG000001630_00093;MGYG000000196_00779;MGYG000002930_01194;MGYG000000098_01850 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 0.5333333333333333 976|Bacteroidetes 1.0 H 0.8666666666666667 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 0.9333333333333333 MGYG000003697_01061 0.06666666666666667 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 803761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1231678 0 0 0 0 2363061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1505326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742853 0 0 0 0 0 0 0 0 0 0 0 0 +(Diethyl)AAGLYKNER MGYG000000222_02092;MGYG000001302.1_01771;MGYG000001783_01717;MGYG000002478_01473;MGYG000004797_02540;MGYG000002438_03363;MGYG000003701_03757;MGYG000001489_04121;MGYG000000174_02073 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FN0E@200643|Bacteroidia,22WXW@171551|Porphyromonadaceae 0.7777777777777778 976|Bacteroidetes 1.0 H 1.0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA 1.0 kbl 1.0 - 1.0 2.3.1.29 1.0 ko:K00639 1.0 ko00260,map00260 1.0 - 1.0 R00371 1.0 RC00004,RC00394 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000222_02092 0.1111111111111111 glycine C-acetyltransferase. 2-amino-3-ketobutyrate coenzyme A ligase. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism 1.0 K00639:kbl, GCAT; glycine C-acetyltransferase [EC:2.3.1.29] 1.0 none 1.0 0 0 0 0 0 0 0 123443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Diethyl)EVEEMCPVAQGVHHGAAPIPEEAK MGYG000004140_00115;MGYG000000252_02593;MGYG000002989_01139;MGYG000004733_02765;MGYG000000142_02730;MGYG000000133_00505;MGYG000000216_01908;MGYG000001338_01295;MGYG000000031_02289;MGYG000000212_00325;MGYG000002298_00730;MGYG000000301_00648 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,25V1D@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004140_00115 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261735 0 396586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Diethyl)GFCAGPSHALIEAAALVK MGYG000001607_00266;MGYG000001315_00855 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,2499C@186801|Clostridia,27V1U@189330|Dorea 0.5 186801|Clostridia 1.0 I 1.0 synthase III 0.5 grdC 1.0 - 1.0 1.21.4.2,1.21.4.3,1.21.4.4 1.0 ko:K21577 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ACP_syn_III,FA_synthesis 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001607_00266 0.5 glycine reductase. | sarcosine reductase. | betaine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. | The reaction is observed only in the direction of sarcosine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.4. | The reaction is observed only in the direction of betaine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.3. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. | [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine. | [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate. 1.0 1.0 1.0 1.0 - 1.0 K21577:grdC; glycine/sarcosine/betaine reductase complex component C subunit beta [EC:1.21.4.2 1.21.4.3 1.21.4.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 884455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Diethyl)MAQQALGMVETR MGYG000004799_00497 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Schaedlerella|s__Schaedlerella sp900765975|m__MGYG000004799 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004799_00497 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2263223 2691847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Diethyl)NDTAEATIEYK MGYG000003694_02663;MGYG000003694_02659 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter faecis|m__MGYG000003694 1.0 COG0791@1|root,COG0791@2|Bacteria,1V37S@1239|Firmicutes,4HGHH@91061|Bacilli 0.5 91061|Bacilli 0.5 M 0.5 NLP P60 protein 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 NLPC_P60,SLH 0.5 - 0.5 - 0.5 - 0.5 - 0.5 MGYG000003694_02663 0.5 - - - - 0.5 0.5 0.5 0.5 - 0.5 - 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147586 0 0 0 0 143537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 200384 0 0 0 0 217970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22267536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809409 0 0 0 0 663135 0 0 0 0 728288 0 0 0 0 0 0 0 0 0 0 +(Diethyl)SAALTILEK MGYG000003202_00870 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__UBA3263|s__UBA3263 sp900759865|m__MGYG000003202 1.0 COG0099@1|root,COG0099@2|Bacteria,4NNGZ@976|Bacteroidetes,2FRYC@200643|Bacteroidia,22Y12@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003202_00870 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02952:RP-S13, rpsM; small subunit ribosomal protein S13 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Diethyl)SCDAFLEGHFLLSSGR MGYG000001300_02620;MGYG000000022_01702;MGYG000002619_01872;MGYG000001255_00856;MGYG000003291_01862;MGYG000004679_00415;MGYG000000195_02742;MGYG000002274_02246;MGYG000002641_01985;MGYG000002272_01960 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3WH1G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Belongs to the CarA family 1.0 carA 1.0 - 1.0 6.3.5.5 1.0 ko:K01956 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_sm_chain,GATase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02620 0.1 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01956:carA, CPA1; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127619 0 0 0 0 421985 0 0 0 0 386498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 301306 0 0 0 0 458705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210765 0 0 0 0 193229 0 0 0 0 0 0 0 0 0 0 +(Diethyl)SEAIAEAAIR MGYG000002156_00335 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550585|m__MGYG000002156 1.0 COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,36EW0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 pyruvate flavodoxin ferredoxin oxidoreductase domain protein 1.0 vorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00174 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFOR_II,POR_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002156_00335 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00174:korA, oorA, oforA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 880508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Diethyl)SGAVER MGYG000001314_01816 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bacteroides_F|s__Bacteroides_F pectinophilus|m__MGYG000001314 1.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,269E9@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal L28 family 1.0 rpmB 1.0 - 1.0 - 1.0 ko:K02902 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001314_01816 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02902:RP-L28, MRPL28, rpmB; large subunit ribosomal protein L28 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Diethyl)VEATFELNDANK MGYG000002494_00458 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1666@1|root,COG1666@2|Bacteria,1RDTF@1224|Proteobacteria,1S3RU@1236|Gammaproteobacteria,3XN7B@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 UPF0234 protein YajQ 1.0 yajQ 1.0 GO:0000049,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 - 1.0 ko:K09767 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF520 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00458 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K09767:yajQ; cyclic-di-GMP-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Diethyl)VLC(Carbamidomethyl)EIEAIAVK MGYG000000179_05387 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,267NT@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 1.0 cca 1.0 - 1.0 2.7.7.19,2.7.7.72 1.0 ko:K00970,ko:K00974 1.0 ko03013,ko03018,map03013,map03018 1.0 - 1.0 R09382,R09383,R09384,R09386 1.0 RC00078 1.0 ko00000,ko00001,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 HD,PEGA,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_05387 1.0 polynucleotide adenylyltransferase. | CCA tRNA nucleotidyltransferase. RNA adenylating enzyme. | tRNA-nucleotidyltransferase. Also acts slowly with CTP.-!-Catalyzes template-independent extension of the 3'-end of a RNA strand by one nucleotide at a time.-!-Cannot initiate a chain de novo.-!-The primer, depending on the source of the enzyme, may be an RNA or DNA fragment or oligo(A) bearing a 3'-OH terminal group.-!-See also EC 2.7.7.6. | The acylation of all tRNAs with an amino acid occurs at the terminal ribose of a 3' CCA sequence.-!-The CCA sequence is added to the tRNA precursor by stepwise nucleotide addition performed by a single enzyme that is ubiquitous in all living organisms.-!-Although the enzyme has the option of releasing the product after each addition, it prefers to stay bound to the product and proceed with the next addition.-!-Formerly EC 2.7.7.21 and EC 2.7.7.25. ATP + RNA(n) = diphosphate + RNA(n)-3'-adenine ribonucleotide. | a tRNA precursor + ATP + 2 CTP = a tRNA with a 3' CCA end + 3 diphosphate. 1.0 1.0 1.0 1.0 Nucleocytoplasmic transport|RNA degradation 1.0 K00970:pcnB; poly(A) polymerase [EC:2.7.7.19]|K00974:cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Diethylphosphate)RTAIQKEIDQLQSEITR MGYG000000389_01367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900550935|m__MGYG000000389 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000389_01367 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1681826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Diethylphosphate)VAIEVPAAMTLDEIWK MGYG000000196_00457 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 MGYG000000196_00457 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4983452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Diisopropylphosphate)FLQASFNYER MGYG000000188_01147;MGYG000004681_01085 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG3716@1|root,COG3716@2|Bacteria,2IDHX@201174|Actinobacteria,4CV2V@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 PTS system mannose fructose sorbose family IID component 1.0 - 1.0 - 1.0 - 1.0 ko:K02747 1.0 ko00052,ko02060,map00052,map02060 1.0 M00277 1.0 R08366 1.0 RC00017 1.0 ko00000,ko00001,ko00002,ko02000 1.0 4.A.6.1.4 1.0 - 1.0 - 1.0 EIID-AGA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000188_01147 0.5 - - - - 1.0 1.0 1.0 1.0 Galactose metabolism|Phosphotransferase system (PTS) 1.0 K02747:agaE; N-acetylgalactosamine PTS system EIID component 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)AAALGFFEAAGYTVENGK MGYG000002926_01410 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_01410 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1052159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1420850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472261 0 +(Dimethyl[AnyN-term](Ethyl)AAGQIDC(Carbamidomethyl)SR MGYG000002506_04505;MGYG000002323_00920 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG3477@1|root,COG3477@2|Bacteria,1MV9E@1224|Proteobacteria,1RYHM@1236|Gammaproteobacteria,3XQGU@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 response to acidic pH 1.0 yagU 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016020,GO:0044464,GO:0050896,GO:0071944 1.0 - 1.0 ko:K08996 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF1440 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04505 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K08996:yagU; putative membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12857722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)AALGAGVDKLANTVR MGYG000000245_00416;MGYG000002492_02075;MGYG000004271_02056;MGYG000000489_01318;MGYG000000271_00294 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000245_00416 0.2 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)AAVAAMNNGDVVLLQNTR MGYG000001255_00368;MGYG000002272_00148;MGYG000001300_02037;MGYG000002223_00500;MGYG000002274_01739;MGYG000003899_01395;MGYG000000022_00457;MGYG000002641_00592;MGYG000002040_00807 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Phosphoglycerate kinase 1.0 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001255_00368 0.1111111111111111 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396040 0 0 0 0 0 0 0 0 0 427993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1154574 0 0 0 0 1148119 0 0 0 0 1072067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 719932 0 0 0 0 0 0 0 0 0 457403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)ADKEMTAAGK MGYG000000084_02247;MGYG000001157_02455 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000084_02247 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2552928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106739 0 0 0 0 61883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)AGNDANVAALGEMWQGGGK MGYG000002492_02667 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,2684W@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 GK 1.0 ROK family 1.0 glcK 1.0 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_02667 1.0 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Galactose metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Neomycin, kanamycin and gentamicin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00845:glk; glucokinase [EC:2.7.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1152262 0 0 0 0 713091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)ATVESGGAEVGTK MGYG000001306_00336 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG3637@1|root,COG3637@2|Bacteria,4NRZA@976|Bacteroidetes,2FQ3Q@200643|Bacteroidia,4AQ2G@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 COG NOG19089 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,OMP_b-brl,OMP_b-brl_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_00336 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5495325 0 0 0 0 8172205 0 0 0 0 6155824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302020 0 0 0 0 652083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)EDGAAITYK MGYG000000036_00872 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Pseudoruminococcus|s__Pseudoruminococcus massiliensis|m__MGYG000000036 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000036_00872 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)EDIATAIVTGVEMFR MGYG000002997_01472 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Streptococcaceae|g__Lactococcus_A|s__Lactococcus_A piscium_C|m__MGYG000002997 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,42CX2@671232|Streptococcus anginosus group 1.0 91061|Bacilli 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 1.0 - 1.0 ko:K02358,ko:K15771 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002997_01472 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K02358:tuf, TUFM; elongation factor Tu|K15771:ganP, mdxF; arabinogalactan oligomer / maltooligosaccharide transport system permease protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 612058 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)FGQGEAAPVVAPAPAPAPEVQTK MGYG000002515_01045;MGYG000002323_01572;MGYG000002506_00283;MGYG000002507_01860 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3XMXT@561|Escherichia 0.75 1236|Gammaproteobacteria 1.0 M 1.0 Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes 0.75 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_01045 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03286:TC.OOP; OmpA-OmpF porin, OOP family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5322900 0 4713103 0 0 4341652 0 0 0 0 0 0 4554505 0 0 0 0 0 0 0 5039824 0 4154497 5500472 4215649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)IVSGGTDNHLMLVDLR MGYG000004712_00408;MGYG000000074_00316;MGYG000001415_00301;MGYG000000206_00151;MGYG000000003_00862;MGYG000001338_00197 domain d__Bacteria 1.0 COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,2FM07@200643|Bacteroidia,22U20@171550|Rikenellaceae 0.5 186801|Clostridia 0.5 E 1.0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism 1.0 glyA 1.0 - 1.0 2.1.2.1 1.0 ko:K00600 1.0 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 1.0 M00140,M00141,M00346,M00532 1.0 R00945,R09099 1.0 RC00022,RC00112,RC01583,RC02958 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 SHMT 1.0 - 1.0 - 1.0 - 1.0 GH13_11 1.0 MGYG000004712_00408 0.16666666666666666 glycine hydroxymethyltransferase. threonine aldolase. Also catalyzes the reaction of glycine with acetaldehyde to form L-threonine, and with 4-trimethylammoniobutanal to form 3-hydroxy- N(6),N(6),N(6)-trimethyl-L-lysine. (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)- 5,6,7,8-tetrahydrofolate + L-serine. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Cyanoamino acid metabolism|Glyoxylate and dicarboxylate metabolism|One carbon pool by folate|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|Antifolate resistance 1.0 K00600:glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 747127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1188433 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)KKENAVPEIIDNVEALEAK MGYG000000038_01608 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena|m__MGYG000000038 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,27V4C@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_01608 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7823473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)NALILSEKEENYK MGYG000004733_01558;MGYG000000142_02503;MGYG000000031_02025;MGYG000000133_01785 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase delta subunit 1.0 acsD 1.0 - 1.0 2.1.1.245 1.0 ko:K00194 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_01558 0.25 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00194:cdhD, acsD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 145236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1164943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)NVLSGK MGYG000003683_00886 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CYY6@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00886 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02356:efp; elongation factor P 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 743976 0 0 0 0 3071391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1695212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)QAIPEHLDIDVTELK MGYG000001056_01611 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900556395|m__MGYG000001056 1.0 COG1825@1|root,COG1825@2|Bacteria,4NEN6@976|Bacteroidetes,2FN3J@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance 1.0 ctc 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02897 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L25p,Ribosomal_TL5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001056_01611 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02897:RP-L25, rplY; large subunit ribosomal protein L25 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1214108 0 0 0 0 0 0 0 0 0 0 0 1159664 0 0 0 0 0 0 0 0 0 0 0 1509525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)SGDIWEVHTNQGVFETK MGYG000000076_01007 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia intestinalis|m__MGYG000000076 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 1.0 186801|Clostridia 1.0 S 1.0 BFD-like [2Fe-2S] binding domain 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000076_01007 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1955242 1779505 2093827 0 0 1643550 0 1930943 0 0 2575002 0 0 0 0 0 0 0 2744159 0 2355362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)SIANYLAEQGAK MGYG000002717_00189;MGYG000004876_00379 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,2FMB9@200643|Bacteroidia,4AM6Q@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Oxidoreductase, short chain dehydrogenase reductase family protein 1.0 uxuB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002717_00189 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1322485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 715814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 484745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)SILLTAQEMNSPVILGVSEGAGK MGYG000000251_01798 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter saccharivorans|m__MGYG000000251 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_01798 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2074780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)TDDTDAQC(Carbamidomethyl)EAAK MGYG000000022_00190;MGYG000000489_00610;MGYG000004414_01745;MGYG000001300_00328;MGYG000000573_00415;MGYG000001157_01716;MGYG000002619_02272 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae 0.7142857142857143 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 0.7142857142857143 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,NAD_binding_7,TP_methylase 0.7142857142857143 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00190 0.14285714285714285 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1491176 0 0 0 0 0 0 0 1370981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2104184 0 0 0 1631793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Dimethyl[AnyN-term](Ethyl)VRPDFVVSTEPTDGGIYR MGYG000002994_00683;MGYG000000179_04171;MGYG000000198_04462 domain d__Bacteria 1.0 COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,267KB@186813|unclassified Clostridiales 0.6666666666666666 186801|Clostridia 0.6666666666666666 E 1.0 Peptidase dimerisation domain 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002994_00683 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 963815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ESP_2H(10))ANYSNGTLYNQK MGYG000000198_03147;MGYG000004087_00695 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,21Y97@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_03147 0.5 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 206524 0 0 0 0 0 0 2014821 0 0 0 2497929 0 0 0 0 0 0 0 0 371868 0 0 0 0 0 0 0 0 3944647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2034518 0 0 0 2106233 0 0 0 0 1150737 0 0 0 0 0 0 0 0 1589011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1608834 0 573533 0 0 0 102927 0 0 0 0 542381 0 0 0 0 0 0 0 0 299141 0 0 0 0 0 0 0 0 0 0 300980 0 0 0 0 0 0 0 0 8905035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10167925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ESP_2H(10))EALQTC(Carbamidomethyl)LDVVNQNR MGYG000000133_01598 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,3XZBA@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GARP,HrpE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01598 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ESP_2H(10))FDPVNSLVSGSMTEQQWIDGIK MGYG000002274_00295;MGYG000001300_00512 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_00295 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10200:ngcE; N-acetylglucosamine transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ESP_2H(10))MVDDAEMLELVEMEMR MGYG000001313_00097 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_00097 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ESP_2H(10))YAIPAFNFNNMEQMQAIIK MGYG000000243_02506 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02506 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2509144 0 0 0 0 132895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1012295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Ethylphosphate)GPNHGPAPIPEEGK MGYG000004876_02447;MGYG000003312_00750;MGYG000003554_01511;MGYG000001433_00320;MGYG000002560_00821;MGYG000001370_00749;MGYG000000701_01016;MGYG000001345_01938;MGYG000002603_00278;MGYG000001378_03490;MGYG000002455_00322;MGYG000000243_00196;MGYG000000098_01020;MGYG000002080_00204;MGYG000000236_00538;MGYG000001770_01219;MGYG000002561_00907;MGYG000003367_01951;MGYG000002834_01892;MGYG000003891_01819;MGYG000004748_00173;MGYG000000196_00898;MGYG000001780_00166;MGYG000000029_00188;MGYG000004185_01309;MGYG000002133_00565;MGYG000002281_03939;MGYG000004797_02908;MGYG000003697_02278;MGYG000003363_00818;MGYG000001657_01849;MGYG000001346_01122;MGYG000004456_01424;MGYG000001806_00887;MGYG000004479_00890;MGYG000003681_01495;MGYG000000707_02289;MGYG000002293_01604;MGYG000000272_02235 domain d__Bacteria 1.0 COG1196@1|root,COG1196@2|Bacteria,1TR05@1239|Firmicutes,24BXV@186801|Clostridia,25WTM@186806|Eubacteriaceae 0.6153846153846154 186801|Clostridia 0.6153846153846154 D 0.6153846153846154 nuclear chromosome segregation 0.6153846153846154 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 0.6153846153846154 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004876_02447 0.02564102564102564 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 925948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1705119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Ethylphosphate)IIGDLELDQTLTSR MGYG000002279_00846 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena_B|m__MGYG000002279 1.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,27UYM@189330|Dorea 1.0 186801|Clostridia 1.0 O 1.0 prohibitin homologues 1.0 qmcA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Band_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_00846 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 788926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Ethylphosphate)VIKEKYDANIMFLIQQANIR MGYG000003681_02191 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_02191 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Formyl)DSPYVNDPHDVSIK MGYG000002478_00658 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 2DBBS@1|root,2Z89P@2|Bacteria,4NG8V@976|Bacteroidetes,2FPGU@200643|Bacteroidia,4ANVA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like,SusD-like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00658 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 3678573 0 0 0 0 0 0 0 0 0 0 0 0 986225 0 0 0 0 2551296 0 0 0 0 2711339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2961784 0 0 0 0 0 0 0 0 0 0 0 0 874725 0 0 0 0 687108 0 0 0 0 660244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383539 0 0 0 0 0 0 0 0 0 0 0 0 1276017 0 0 0 0 753832 0 0 0 0 939329 0 0 0 0 0 0 0 0 0 0 +(Formyl)ELGLNSETATVFNLK MGYG000001345_04617;MGYG000002438_01730;MGYG000002033_01132;MGYG000002549_03009;MGYG000001655_03297;MGYG000000243_01838;MGYG000002455_01424;MGYG000003681_02208;MGYG000001337_04099;MGYG000001346_02112;MGYG000002171_01126;MGYG000002218_00618;MGYG000004763_01642;MGYG000003546_01574;MGYG000000044_02644;MGYG000004797_03540;MGYG000001604_00090;MGYG000003363_00033;MGYG000001489_01493;MGYG000004822_01333 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,4AMYK@815|Bacteroidaceae 0.85 976|Bacteroidetes 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_04617 0.05 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2321724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1046675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Formyl)GNTDDMKEC(Carbamidomethyl)LK MGYG000002528_01588 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,248JR@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 PFAM Alcohol dehydrogenase zinc-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 ko:K19956 1.0 ko00051,map00051 1.0 - 1.0 R03234 1.0 RC00089 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01588 1.0 - - - - 1.0 1.0 1.0 1.0 Fructose and mannose metabolism 1.0 K19956:sorE; L-sorbose 1-phosphate reductase [EC:1.1.1.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 988325 0 0 0 617634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 875539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Formyl)GVDKNEIKR MGYG000000196_03974;MGYG000000236_01807;MGYG000004763_01689;MGYG000000013_02251;MGYG000002281_02290 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_03974 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1980765 0 0 0 0 0 0 +(Formyl)MDKMADVLGR MGYG000000045_02691 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG1455@1|root,COG1455@2|Bacteria 1.0 2|Bacteria 1.0 G 1.0 protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HisKA,PTS_EIIC,PTS_IIB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000045_02691 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Formyl)MDQMLLAK MGYG000002485_02054;MGYG000004893_01695;MGYG000004828_00160 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0636@1|root,COG0636@2|Bacteria,37AJP@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_02054 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02110:ATPF0C, atpE; F-type H+-transporting ATPase subunit c 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 667583 1891886 1280967 0 2152077 2100136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1524625 0 1227289 0 1289373 0 0 0 0 0 2479160 917525 0 0 0 924533 962086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184091 0 0 89223 0 147007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Formyl)MFSYLQK MGYG000002485_02525 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,378A5@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 G 1.0 PTS system 1.0 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_02525 1.0 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Phosphotransferase system (PTS) 1.0 K02803:nagEb; N-acetylglucosamine PTS system EIIB component [EC:2.7.1.193]|K02804:nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1446602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1582687 0 1196388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114490 0 200960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Formyl)MKELVAK MGYG000000074_00307 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 S 1.0 Histone H1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Hc1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00307 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 474948 0 223643 0 0 0 0 1002834 0 213500 0 0 0 0 0 0 0 232924 0 0 0 0 0 0 0 0 0 0 0 622752 0 0 0 0 0 0 0 0 628260 0 499911 0 0 0 0 0 0 910132 0 0 0 0 0 0 0 991048 0 0 0 0 0 0 0 0 0 0 0 476668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 514712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1930590 0 0 0 0 0 0 0 0 0 0 1388919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1274644 0 0 0 0 0 0 0 0 0 0 4440577 5826601 0 0 0 0 0 0 0 0 3606555 0 4535016 0 0 0 0 2450161 0 2926836 0 0 0 0 0 0 0 3101331 0 0 0 0 0 0 +(Formyl)MKELVEK MGYG000004019_00977;MGYG000002281_03860;MGYG000004748_00642;MGYG000003922_01592;MGYG000001346_02634;MGYG000002561_03014;MGYG000000224_00965;MGYG000002470_01930;MGYG000002549_00791;MGYG000002455_04930;MGYG000000098_00150;MGYG000001370_01432;MGYG000000196_01092;MGYG000001470_03728;MGYG000000029_02290;MGYG000003363_02435;MGYG000000013_00813;MGYG000000003_01005;MGYG000001378_02536;MGYG000000054_03375;MGYG000001345_01255 domain d__Bacteria 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes,2FUJN@200643|Bacteroidia,4AS55@815|Bacteroidaceae 0.9047619047619048 976|Bacteroidetes 0.9523809523809523 S 0.9523809523809523 COG NOG16623 non supervised orthologous group 0.9047619047619048 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 - 1.0 - 1.0 - 1.0 Hc1 0.9523809523809523 - 1.0 - 1.0 - 1.0 - 0.9523809523809523 MGYG000004019_00977 0.047619047619047616 - - - - 0.9523809523809523 0.9523809523809523 0.9523809523809523 0.9523809523809523 - 0.9523809523809523 - 0.9523809523809523 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8648037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3133491 0 0 6086302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5347614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Formyl)MLAHLLK MGYG000000038_02185;MGYG000001311_02933;MGYG000003582_01256;MGYG000001558_01857;MGYG000002619_02023;MGYG000003374_01118;MGYG000000771_01164;MGYG000001412_01313;MGYG000000272_02321;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000001763_00396;MGYG000000223_00996;MGYG000001711_02099;MGYG000004732_01055;MGYG000001255_00370;MGYG000001482_02362;MGYG000001496_01122;MGYG000004493_00097;MGYG000000002_02120;MGYG000002194_02222;MGYG000004271_00554;MGYG000002966_00075;MGYG000004317_00142;MGYG000000233_00345;MGYG000001577_01888;MGYG000000174_02692;MGYG000001652_01009;MGYG000000077_00219;MGYG000000127_04855;MGYG000002993_00787;MGYG000002945_00682;MGYG000000229_00395;MGYG000004610_00503;MGYG000002098_00013;MGYG000002212_00259;MGYG000004826_01307;MGYG000001606_02632;MGYG000000213_00374;MGYG000003465_00706;MGYG000001542_01437;MGYG000002517_01026;MGYG000004707_01697;MGYG000000212_01474;MGYG000002126_00535;MGYG000000515_01608;MGYG000001338_02547;MGYG000003074_01265;MGYG000001493_05257;MGYG000004757_01889;MGYG000002141_01131;MGYG000000217_00275;MGYG000001439_00571;MGYG000000280_02459;MGYG000000249_01352;MGYG000003695_01114;MGYG000004691_00618;MGYG000002641_00563;MGYG000000193_03247;MGYG000000140_01181;MGYG000000080_03115;MGYG000002279_00557;MGYG000004799_00704;MGYG000001814_01253;MGYG000003656_01296;MGYG000000242_02076;MGYG000002492_01379;MGYG000000198_04065;MGYG000001334_01647;MGYG000001199_01005;MGYG000001658_00407;MGYG000001688_03910;MGYG000000278_03657;MGYG000001319_00348;MGYG000000495_01130;MGYG000001303_01883;MGYG000000187_02264;MGYG000003504_01686;MGYG000000371_00136;MGYG000004519_00423;MGYG000000097_00328;MGYG000001525_01747;MGYG000000615_00488;MGYG000001423_00991;MGYG000001157_00577;MGYG000000171_00850;MGYG000000195_01135;MGYG000001008_00728;MGYG000000271_03250;MGYG000000562_01218;MGYG000000022_00437;MGYG000000133_02283;MGYG000002298_02410;MGYG000000489_00503;MGYG000004600_00849;MGYG000000399_00360;MGYG000003694_01737;MGYG000001607_01815;MGYG000000230_01325;MGYG000003355_00996;MGYG000000484_01691;MGYG000001710_00672;MGYG000003001_00320;MGYG000000205_02269;MGYG000000145_03615;MGYG000002528_00367;MGYG000004140_01100;MGYG000002188_01071;MGYG000002286_00420;MGYG000000164_00800;MGYG000001748_01525;MGYG000001714_01796;MGYG000002946_02881;MGYG000000150_00838;MGYG000000404_00344;MGYG000004815_01345;MGYG000000141_02825;MGYG000003552_01242;MGYG000003702_00925;MGYG000001781_01334;MGYG000001542_02015;MGYG000002304_00547;MGYG000004740_01468;MGYG000000045_02136;MGYG000000162_00065;MGYG000000089_01653;MGYG000004296_01958;MGYG000002155_00766;MGYG000000179_02084;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000001299_00204;MGYG000000251_00555;MGYG000002992_00164;MGYG000002974_01418;MGYG000002997_01277;MGYG000001237_01808;MGYG000004785_01017;MGYG000002025_02240;MGYG000002963_04095;MGYG000000463_00862;MGYG000001602_01805;MGYG000002052_00078;MGYG000001970_02077;MGYG000004246_01300;MGYG000000153_00303;MGYG000001315_01699;MGYG000001627_00130;MGYG000001469_02299;MGYG000003409_01628;MGYG000003891_00096;MGYG000001310_02090;MGYG000002445_01920;MGYG000000325_00586;MGYG000000909_00644;MGYG000002234_00398;MGYG000003431_01105;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000004809_00788;MGYG000003450_00202;MGYG000003701_01708;MGYG000001954_02254;MGYG000002638_00362;MGYG000000215_01375;MGYG000001065_01088;MGYG000004810_01402;MGYG000000100_02166;MGYG000002131_02428;MGYG000003335_00316;MGYG000000084_01085;MGYG000001300_02008;MGYG000004866_01631;MGYG000003937_01177;MGYG000000252_01324;MGYG000000365_00999;MGYG000000301_01012;MGYG000004722_00591;MGYG000001186_01925;MGYG000004087_02290;MGYG000000312_01508;MGYG000000204_00778;MGYG000003013_01053;MGYG000002857_01020;MGYG000004288_00401;MGYG000000175_00767;MGYG000004714_00143;MGYG000003133_02653;MGYG000000281_02732;MGYG000001619_01736;MGYG000000398_00286;MGYG000001683_01827;MGYG000001421_02311;MGYG000004789_01485;MGYG000003812_01036;MGYG000004735_01946;MGYG000003503_01071;MGYG000004809_00408;MGYG000004593_01977 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.20398009950248755 186801|Clostridia 0.7711442786069652 C 0.5870646766169154 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.47761194029850745 gap 0.9552238805970149 - 0.9154228855721394 1.2.1.12 0.9850746268656716 ko:K00134 0.9850746268656716 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9850746268656716 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9850746268656716 R01061 0.9850746268656716 RC00149 0.9850746268656716 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9850746268656716 - 0.9950248756218906 - 1.0 - 0.9850746268656716 Gp_dh_C,Gp_dh_N 0.9850746268656716 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_02185 0.004975124378109453 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9850746268656716 0.9850746268656716 0.9850746268656716 0.9850746268656716 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9850746268656716 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9850746268656716 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Formyl)MNELVAK MGYG000000243_03163 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes,2FUJN@200643|Bacteroidia,4AS55@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG16623 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Hc1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03163 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 75891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635800 0 0 0 0 726566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Formyl)MNKMEDLINMTK MGYG000004719_01173;MGYG000002517_02144 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 2E4IR@1|root,32ZDT@2|Bacteria,1VENP@1239|Firmicutes,24PCY@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004719_01173 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236196 0 0 0 0 84091 0 0 1413441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Formyl)MNKYELALVVSAK MGYG000000171_00776;MGYG000000002_03074;MGYG000001338_00370;MGYG000000997_00916;MGYG000003821_02187;MGYG000002966_02660;MGYG000001777_00649;MGYG000004719_00775;MGYG000000184_02505;MGYG000000213_02194;MGYG000000271_02366;MGYG000000245_01910;MGYG000000201_01588;MGYG000004271_01915;MGYG000004733_01692;MGYG000000301_02038;MGYG000002492_02964;MGYG000002517_03265;MGYG000000806_00865 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3Y068@572511|Blautia 0.5789473684210527 186801|Clostridia 1.0 J 1.0 Binds together with S18 to 16S ribosomal RNA 1.0 rpsF 1.0 - 1.0 - 1.0 ko:K02990 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_00776 0.05263157894736842 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02990:RP-S6, MRPS6, rpsF; small subunit ribosomal protein S6 1.0 none 1.0 0 0 0 0 0 470104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 373800 0 0 0 0 0 0 0 0 2335071 0 0 0 0 0 487484 0 0 0 0 0 0 326196 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3348433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2288677 0 1680413 0 2955913 0 0 0 0 2875660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2984732 0 0 0 0 0 0 +(Formyl)MPEKIEELVR MGYG000002775_00885;MGYG000004875_00297;MGYG000001718_01281;MGYG000002947_00531;MGYG000003266_00117;MGYG000002065_01444;MGYG000002961_01719;MGYG000003122_01407;MGYG000002050_01845;MGYG000000188_00186 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CUI3@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Arginyl-tRNA synthetase 1.0 argS 1.0 - 1.0 6.1.1.19 1.0 ko:K01887 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03646 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002775_00885 0.1 arginine--tRNA ligase. arginyl-tRNA synthetase. - ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01887:RARS, argS; arginyl-tRNA synthetase [EC:6.1.1.19] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 422861 0 0 0 0 334426 0 0 0 0 0 0 0 0 0 0 0 0 0 238908 281280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261534 0 0 0 0 481569 0 0 0 0 0 0 0 0 0 0 0 0 0 125102 263993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228082 0 0 0 0 401710 0 0 0 0 0 0 0 0 0 0 0 0 0 580248 278092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189266 0 0 0 0 1303654 0 0 0 0 0 0 0 0 0 0 0 0 0 1642528 791252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 542583 0 0 0 0 0 0 0 0 +(Formyl)MQKEALGMIETK MGYG000000262_00362 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,25WKA@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_00362 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Formyl)MTDFQYLAR MGYG000003899_00591;MGYG000003291_01608;MGYG000003166_00738;MGYG000002651_01639;MGYG000001300_02373;MGYG000002619_01675;MGYG000000022_01425;MGYG000002223_00953;MGYG000002641_02167;MGYG000004679_00018 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3WK2P@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 - 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003899_00591 0.1 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02110:ATPF0C, atpE; F-type H+-transporting ATPase subunit c 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334395 0 676222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398219 0 200257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Formyl)TLSGENAFK MGYG000000133_01646;MGYG000002517_01317;MGYG000000184_00874;MGYG000001338_01597;MGYG000003821_02419;MGYG000004785_00785;MGYG000002298_00919;MGYG000000171_00267;MGYG000000301_00414;MGYG000000806_01910 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae 0.9 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 - 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01646 0.1 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01872:AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2157756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2296411 0 0 0 0 0 0 +(FormylMet)DKMADVLGR MGYG000000045_02691 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG1455@1|root,COG1455@2|Bacteria 1.0 2|Bacteria 1.0 G 1.0 protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HisKA,PTS_EIIC,PTS_IIB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000045_02691 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 2129108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 729966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1440147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(FormylMet)NKMEDLINMTK MGYG000004719_01173;MGYG000002517_02144 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 2E4IR@1|root,32ZDT@2|Bacteria,1VENP@1239|Firmicutes,24PCY@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004719_01173 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 307776 0 0 0 0 0 0 0 0 0 0 0 0 310630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 984829 0 0 0 0 0 0 0 0 0 0 0 0 980128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 930361 0 0 0 0 0 0 0 0 0 0 0 0 4433214 0 0 0 0 0 0 0 0 0 0 0 +(FormylMet)NKYELALVVSAK MGYG000000184_02505;MGYG000000271_02366;MGYG000001338_00370;MGYG000003821_02187;MGYG000000301_02038;MGYG000002492_02964;MGYG000004719_00775;MGYG000002517_03265;MGYG000000806_00865 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3Y068@572511|Blautia 0.5555555555555556 186801|Clostridia 1.0 J 1.0 Binds together with S18 to 16S ribosomal RNA 1.0 rpsF 1.0 - 1.0 - 1.0 ko:K02990 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_02505 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02990:RP-S6, MRPS6, rpsF; small subunit ribosomal protein S6 1.0 none 1.0 406446 0 339227 0 0 423911 349813 0 0 0 741166 761918 0 0 0 286294 0 347205 0 0 0 800072 547916 0 300405 319814 396483 828965 0 765781 0 0 366229 0 0 253960 0 378387 407765 0 578342 0 0 353128 507911 0 0 0 854273 116653 0 0 0 519831 0 3046027 284107 0 0 177396 1610339 715255 314654 425139 678767 2256039 0 496548 0 0 540869 0 0 559518 348128 807726 448487 0 1035141 0 0 416598 0 0 0 0 639290 533687 0 0 0 1089783 0 626138 341781 0 0 775014 1042309 564614 369621 0 438268 1609547 0 524068 0 0 1411946 0 0 312542 272403 1276310 132685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409793 0 0 0 0 0 0 323394 0 178974 417979 0 0 0 0 0 0 0 213755 221091 0 2810858 0 0 0 0 0 3201891 0 0 0 2804908 1909092 0 0 0 2215306 0 485227 2068430 0 0 2203286 1122856 2634918 3340218 3059914 3440310 1567357 0 1465106 0 0 4302884 0 0 3147989 2193628 0 +(FormylMet)VVQHNLTAMNANR MGYG000004271_01770;MGYG000000153_01160;MGYG000000271_01499;MGYG000000404_00502;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01770 0.2 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1309110 0 0 0 0 0 0 0 0 0 0 909042 0 +(GIST-Quat)APFGPGANPMHGR MGYG000002506_00229 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1RM96@1236|Gammaproteobacteria,3XMX2@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 formate C-acetyltransferase activity 1.0 pflB 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECH74115_1262.ECH74115_1064,iECIAI39_1322.ECIAI39_2245,iECSP_1301.ECSP_1007,iECs_1301.ECs0986,iEcSMS35_1347.EcSMS35_2218,iG2583_1286.G2583_1138,iSDY_1059.SDY_2358,iZ_1308.Z1248 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00229 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 761388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)ATSDQAEEVC(Carbamidomethyl)AAIR MGYG000001645_00996 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eubacterium_G|s__Eubacterium_G sp900550135|m__MGYG000001645 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,27IBE@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001645_00996 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 497144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 871541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1179806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)AVAPTVAVCSNC(Carbamidomethyl)GAATLYHR MGYG000003539_00448 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900769405|m__MGYG000003539 1.0 COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,2FUZD@200643|Bacteroidia,22UKC@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal L32p protein family 1.0 rpmF 1.0 - 1.0 - 1.0 ko:K02911 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L32p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003539_00448 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02911:RP-L32, MRPL32, rpmF; large subunit ribosomal protein L32 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 625582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2226591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)DGPTALILSR MGYG000002506_02537 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,3XMMK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate 1.0 tktA 1.0 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,ic_1306.c2990 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02537 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 790628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)DNLYVAEC(Carbamidomethyl)YANKGPTMK MGYG000002966_02570 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900551075|m__MGYG000002966 1.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3XZZ2@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome 1.0 rplV 1.0 - 1.0 - 1.0 ko:K02890 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L22 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002966_02570 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02890:RP-L22, MRPL22, rplV; large subunit ribosomal protein L22 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 971414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)GGLVTAGNASGINDGAAAIVVMSEEK MGYG000000271_02104;MGYG000002517_00540 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02104 0.5 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)GQHVIVDGK MGYG000004642_01927 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG3628@1|root,COG3628@2|Bacteria,1VFFX@1239|Firmicutes 1.0 1239|Firmicutes 1.0 S 1.0 Protein of unknown function (DUF2634) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF2634 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004642_01927 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 495110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1060262 0 0 0 0 0 0 0 0 0 +(GIST-Quat)IDPIFMDLAR MGYG000000271_00961 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG1145@1|root,arCOG02189@2157|Archaea,2Y1K1@28890|Euryarchaeota,246P5@183980|Archaeoglobi 1.0 183980|Archaeoglobi 1.0 C 1.0 4Fe-4S dicluster domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4,Fer4_21,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00961 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)IPDGTTLIDPATGK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01126 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 131004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295962 0 0 0 0 130441 0 0 1730040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1791481 0 0 0 0 1799120 0 0 528329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 727482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 551531 0 0 0 0 819241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203728 +(GIST-Quat)KATIEKGQPLDLEVANVVASVMK MGYG000000084_01219;MGYG000001627_02121 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 1.0 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000084_01219 0.5 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Glyoxylate and dicarboxylate metabolism|Nitrogen metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Biosynthesis of amino acids|Two-component system|Necroptosis|Glutamatergic synapse|GABAergic synapse 1.0 K01915:glnA, GLUL; glutamine synthetase [EC:6.3.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4317137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6294058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)LPGVAAANDK MGYG000001199_01004;MGYG000000142_01978 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3XYK6@572511|Blautia 0.5 186801|Clostridia 0.5 F 0.5 Psort location Cytoplasmic, score 0.5 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001199_01004 0.5 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1229273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)MFGAEGFEIVAINDLTSPK MGYG000002298_02410;MGYG000000142_01979;MGYG000000171_00850 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_02410 0.3333333333333333 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)NAALDLAEK MGYG000002545_02171;MGYG000003166_00582;MGYG000001255_00661;MGYG000002040_00479 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 2ET0Z@1|root,33KJ7@2|Bacteria,1VNW5@1239|Firmicutes,254DV@186801|Clostridia,3WQEJ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-ribbon_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002545_02171 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2491955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)RPDFVVSTEPTDGGIYR MGYG000000198_04462 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,267KB@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Peptidase dimerisation domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04462 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2980491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)SGVLTGLPDAYGR MGYG000002494_01412;MGYG000000037_00273;MGYG000002534_01733;MGYG000001692_01065;MGYG000000323_00781;MGYG000002515_00999;MGYG000000337_02065;MGYG000002507_03821;MGYG000000093_01913;MGYG000002506_00229;MGYG000000989_01728;MGYG000001712_00487;MGYG000001395_02012 domain d__Bacteria 1.0 COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1RM96@1236|Gammaproteobacteria,3XMX2@561|Escherichia 0.3076923076923077 1236|Gammaproteobacteria 0.5384615384615384 C 1.0 formate C-acetyltransferase activity 0.3076923076923077 pflB 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 0.5384615384615384 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECH74115_1262.ECH74115_1064,iECIAI39_1322.ECIAI39_2245,iECSP_1301.ECSP_1007,iECs_1301.ECs0986,iEcSMS35_1347.EcSMS35_2218,iG2583_1286.G2583_1138,iSDY_1059.SDY_2358,iZ_1308.Z1248 0.5384615384615384 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01412 0.07692307692307693 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1337994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)SVQALIDC(Carbamidomethyl)MQEFEK MGYG000002171_00856;MGYG000000243_00367;MGYG000002478_03725;MGYG000002549_01442 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,2FMET@200643|Bacteroidia,4AKSS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_00856 0.25 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Vitamin B6 metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00831:serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)TANMISFMADVIGIR MGYG000001714_00587 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus_A|s__Coprococcus_A catus|m__MGYG000001714 1.0 COG0078@1|root,COG0078@2|Bacteria,1TNY4@1239|Firmicutes,249P4@186801|Clostridia,26870@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 1.0 ygeW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001714_00587 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)TEPVYYEPAPAPAPK MGYG000000243_02431;MGYG000002171_00876 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2885@1|root,COG2885@2|Bacteria,4NKM0@976|Bacteroidetes,2FP8P@200643|Bacteroidia,4AN93@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 COG2885 Outer membrane protein and related peptidoglycan-associated 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HALZ,OMP_b-brl,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02431 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)TFNEYGIDGK MGYG000000243_02990 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02990 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507063 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)VYPAVQGQALK MGYG000000243_01886;MGYG000002171_01694 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01886 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3465418 3404630 2828835 2838720 4093879 2978622 3042031 0 2182015 0 0 0 0 0 2669335 4555063 3713116 8009643 0 0 2696577 3914539 7026731 3716622 0 3595620 0 7116668 0 0 3547028 0 2991895 0 4685469 0 2760897 2643920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat)YKDPDYSAK MGYG000000196_04182;MGYG000003367_02308;MGYG000000098_00764;MGYG000001345_00362;MGYG000002549_02853;MGYG000002455_00013 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2207@1|root,COG2207@2|Bacteria,4NVK3@976|Bacteroidetes,2FRSW@200643|Bacteroidia,4AN3S@815|Bacteroidaceae 0.8333333333333334 976|Bacteroidetes 1.0 K 0.8333333333333334 transcriptional regulator (AraC 0.8333333333333334 - 1.0 - 1.0 - 0.8333333333333334 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 HTH_18,TPR_8 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04182 0.16666666666666666 - - - - 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 - 1.0 - 0.8333333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 815375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat_2H(3))ATQNSYSVEAAMAK MGYG000001564_00904 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster clostridioformis_A|m__MGYG000001564 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001564_00904 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat_2H(3))DNISENTSSAESR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00135 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1033845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat_2H(3))DQPFLMPVEDVFTISGR MGYG000001500_01929;MGYG000004201_01254 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,267PG@186813|unclassified Clostridiales 0.5 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001500_01929 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat_2H(3))GSIC(Carbamidomethyl)DVADEVIDYLNAK MGYG000001300_01192 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001300_01192 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat_2H(6))IPFLHFFDGFR MGYG000002794_00026 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp003487665|m__MGYG000002794 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,36EA6@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 - 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_10,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002794_00026 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 5398599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(GIST-Quat_2H(9))VFEFENFTHGSR MGYG000000196_04506;MGYG000002438_03839;MGYG000002455_00199 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 0.6666666666666666 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04506 0.3333333333333333 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Galactosyl)EGWYLVNTSGR MGYG000001619_00313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA9502|s__UBA9502 sp900540335|m__MGYG000001619 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001619_00313 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 229472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 206288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Galactosyl)SAEKLSSGYR MGYG000000404_00502 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA11774|s__UBA11774 sp003507655|m__MGYG000000404 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000404_00502 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 9524267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Galactosyl)SIPVGLSYEYQNIVFDAR MGYG000003697_01780 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,2FU05@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 Outer membrane protein beta-barrel domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OMP_b-brl,OMP_b-brl_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01780 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Galactosyl)SREYPRNYINTGISAIDGLTTLIR MGYG000000133_02040 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,3XZA3@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit 1.0 ntpB 1.0 - 1.0 - 1.0 ko:K02118 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GH130 1.0 MGYG000000133_02040 1.0 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways 1.0 K02118:ATPVB, ntpB, atpB; V/A-type H+/Na+-transporting ATPase subunit B 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25228221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAAAGVGISK MGYG000001306_00929;MGYG000001364_03302;MGYG000003693_01486 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia,4ARQC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_00929 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02110:ATPF0C, atpE; F-type H+-transporting ATPase subunit c 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2468820 0 0 0 0 0 0 0 0 0 2336937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAAEAVATSEETR MGYG000000074_02304 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG2911@1|root,COG2911@2|Bacteria,4NF7F@976|Bacteroidetes,2FNBJ@200643|Bacteroidia,22UXT@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 TamB, inner membrane protein subunit of TAM complex 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AsmA,TamB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02304 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1321665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAAEYFGVK MGYG000000243_02695 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0614@1|root,COG0614@2|Bacteria,4NEF0@976|Bacteroidetes,2FNDC@200643|Bacteroidia,4AMJ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02695 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 382954 487625 0 0 0 0 487264 0 0 0 0 0 0 0 0 0 0 330757 274286 339952 0 0 0 0 0 0 0 0 0 0 0 604191 498874 0 0 0 615652 0 266612 445052 0 0 0 0 675978 0 0 0 0 0 0 0 0 0 0 355473 402368 357502 0 0 0 0 0 0 0 0 0 0 0 341282 353340 0 0 0 217298 0 71010 176626 0 0 0 0 136108 0 0 0 0 0 0 0 0 0 0 128543 118623 171199 0 0 0 0 0 0 0 0 0 0 0 127018 92278 0 0 0 183753 0 0 86098 0 0 0 0 172845 0 0 0 0 0 0 0 0 0 0 107515 0 210394 0 0 0 0 0 0 0 0 0 0 0 134921 122932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAAPAKK MGYG000003697_01978;MGYG000002293_00413 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,2FMF1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01978 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 51875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13095 0 0 0 0 1762704 0 0 0 0 43783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55587 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAAPVEEVKTEAVAAAETEAAPAK MGYG000000198_03437 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24R6P@186801|Clostridia,220KI@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_03437 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 625644 0 0 0 0 0 0 0 0 675408 0 0 0 542400 437806 0 0 0 0 651393 0 0 0 0 0 638461 0 0 682773 721946 0 0 0 0 567460 0 629969 0 193298 0 0 0 0 0 0 0 0 236702 0 0 0 276135 267542 0 0 0 0 255513 0 0 0 0 0 323058 0 0 156539 204030 0 0 0 0 272111 0 248168 0 590711 0 0 0 0 0 0 0 0 389673 0 0 0 510929 666826 0 0 0 0 305851 0 0 0 0 0 614804 0 0 325181 260262 0 0 0 0 290288 0 269375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150010 0 0 0 0 0 260537 0 0 0 0 0 0 0 0 0 201815 0 0 0 0 203231 0 0 0 336736 0 0 0 0 0 0 0 0 234616 0 0 0 0 0 0 0 0 0 348821 0 0 0 0 0 271918 0 0 344324 228448 0 0 0 0 329879 0 311483 0 +(Gln->pyro-Glu)QADEYKVPR MGYG000004732_02399;MGYG000002224_01124;MGYG000000022_02282;MGYG000001300_00281;MGYG000002619_00484;MGYG000003409_01330;MGYG000001754_00088;MGYG000003412_02031;MGYG000003937_01028;MGYG000002040_01211;MGYG000002057_01067;MGYG000002545_02503;MGYG000000084_01999;MGYG000001157_01851;MGYG000001255_01100;MGYG000002641_00068;MGYG000000039_00482 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.7647058823529411 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000004732_02399 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 486629 0 0 0 0 0 0 2794764 3333151 5523055 3412310 0 0 0 5569150 0 475431 0 0 0 0 0 0 3851624 3781052 0 0 0 0 530758 3225368 512373 427519 0 0 666558 0 0 690039 433430 737461 0 0 3208263 0 376289 476479 6253287 1075941 1326954 603535 237199 0 0 0 0 939706 0 2202178 0 320075 444626 4175500 0 0 0 0 0 783872 0 2871890 0 407237 594319 0 0 1513651 505212 385896 818069 0 925195 0 733884 667111 3884618 855198 751720 853419 777346 0 165231 643644 0 698636 0 716684 1156709 794504 444022 0 0 0 0 0 333453 0 710896 674437 823972 524210 1649310 0 2940701 1826535 2291654 2372790 2641172 0 2821123 0 2532013 3192832 2727559 2318398 2143984 2553837 2187266 3199754 2800480 2097670 0 2870468 0 2858055 3048937 0 2069097 4507841 0 0 0 0 2879272 2276995 1268563 1997601 2386307 3126850 2398998 0 1690071 2279016 5301172 0 2042519 0 0 0 1891530 741868 0 0 815482 0 0 0 0 0 0 2299140 0 2447292 1947133 0 829065 3275912 0 0 0 0 659637 2186151 0 1397050 0 0 +(Gln->pyro-Glu)QADGAAQDFFVVDDDRVAK MGYG000002293_01420;MGYG000003697_02155 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01420 0.5 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K00008:SORD, gutB; L-iditol 2-dehydrogenase [EC:1.1.1.14] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 666923 0 0 0 0 673472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QADGSRHPFDSFIC(Carbamidomethyl)AK MGYG000001346_01937;MGYG000000196_04945;MGYG000003681_02456;MGYG000001345_04193;MGYG000001313_00382;MGYG000002281_01173;MGYG000001661_01094;MGYG000000054_00269 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,2FMSH@200643|Bacteroidia,4AKTZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Oxidoreductase, short chain dehydrogenase reductase family protein 1.0 idnO 1.0 - 1.0 1.1.1.69 1.0 ko:K00046 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_01937 0.125 gluconate 5-dehydrogenase. 5-ketogluconate reductase. - (1) D-gluconate + NADP(+) = 5-dehydro-D-gluconate + H(+) + NADPH. (2) D-gluconate + NAD(+) = 5-dehydro-D-gluconate + H(+) + NADH. 1.0 1.0 1.0 1.0 - 1.0 K00046:idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] 1.0 none 1.0 103299 0 0 99189 0 0 0 0 0 0 0 211668 0 249725 113223 0 0 0 0 0 0 0 0 0 0 236055 0 0 0 183514 289371 0 0 0 168279 0 200320 0 255744 0 0 317126 0 0 0 0 0 0 0 244617 0 339269 388206 0 0 0 198532 0 0 0 0 0 0 370684 0 0 0 373805 199178 0 0 0 359259 0 231836 0 302406 0 0 230119 0 0 0 0 0 0 0 441568 0 381678 173517 0 0 0 274332 0 0 0 0 0 0 505635 0 0 0 0 368311 0 0 0 424314 0 286818 0 354220 0 0 460943 0 0 0 0 0 0 0 436635 0 438688 569273 0 0 0 543412 0 0 0 0 0 0 559078 0 0 0 485945 287406 0 0 0 635604 0 525287 0 0 0 0 207199 0 0 0 0 0 0 0 0 0 174079 228104 0 0 0 0 0 0 0 0 0 0 118096 0 0 0 112253 276479 0 0 0 176895 0 317729 0 +(Gln->pyro-Glu)QADGSVM(Oxidation)LR MGYG000004797_03519;MGYG000000098_03719;MGYG000000013_03985;MGYG000001345_00516;MGYG000000196_02452;MGYG000002560_00163;MGYG000001346_01624;MGYG000003221_00983;MGYG000004185_01554;MGYG000002549_04587;MGYG000001337_03982;MGYG000003681_02801;MGYG000000243_02576;MGYG000002455_01538;MGYG000002478_00894;MGYG000000236_01868;MGYG000003312_02028;MGYG000001378_04409 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004797_03519 0.05555555555555555 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QADGSVMLR MGYG000004797_03519;MGYG000000098_03719;MGYG000000013_03985;MGYG000001345_00516;MGYG000000196_02452;MGYG000002560_00163;MGYG000001346_01624;MGYG000003221_00983;MGYG000004185_01554;MGYG000002549_04587;MGYG000001337_03982;MGYG000003681_02801;MGYG000000243_02576;MGYG000002455_01538;MGYG000002478_00894;MGYG000000236_01868;MGYG000003312_02028;MGYG000001378_04409 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004797_03519 0.05555555555555555 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 648554 0 784625 0 0 0 0 0 714123 0 915942 0 0 744083 0 0 500775 0 617361 0 0 0 0 0 0 0 0 0 572152 0 940216 0 0 0 0 611888 0 0 467994 0 502412 0 0 0 0 0 583405 0 647737 0 0 574834 0 0 389822 0 370438 0 0 0 0 0 0 0 0 0 270345 0 282452 0 0 0 0 373687 0 0 283487 0 354103 0 0 0 0 0 489489 0 636354 0 0 434435 0 0 252644 0 281903 0 0 0 0 0 0 0 0 0 352715 0 394284 0 0 0 0 78596 0 0 249493 0 295599 0 0 0 0 0 418366 0 191435 0 0 466010 0 0 244033 0 0 0 0 0 0 0 0 0 0 0 286878 0 275636 0 0 0 0 246679 0 0 205446 0 648452 0 0 0 0 0 656289 0 657366 0 0 407894 0 0 372434 0 163387 0 0 0 0 0 0 0 0 0 257135 0 102479 0 0 0 0 271882 +(Gln->pyro-Glu)QADGTYSVDITDVK MGYG000001319_01521 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 28JY0@1|root,2Z9ND@2|Bacteria,4NIG7@976|Bacteroidetes,2FV40@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko:K21571 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF5115,SusE,SusF_SusE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001319_01521 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21571:susE_F; starch-binding outer membrane protein SusE/F 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1898402 0 0 0 0 1093007 0 0 0 0 1657683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QADIDSGKETIVGLNK MGYG000000742_00316 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900541605|m__MGYG000000742 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H37I@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000742_00316 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1307031 0 0 0 0 1982969 0 0 0 0 1525807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QADIIMILINDEK MGYG000000212_02114;MGYG000000251_00670;MGYG000000258_00558;MGYG000000262_00972 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3XYWE@572511|Blautia 0.5 186801|Clostridia 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_02114 0.25 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 899021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QADKYGVPR MGYG000004535_00736;MGYG000003383_01370;MGYG000003683_00888;MGYG000001292_02048;MGYG000001423_01465;MGYG000001477_00014;MGYG000002469_00667;MGYG000003452_00659;MGYG000004769_00436;MGYG000002395_00575;MGYG000000036_01379;MGYG000002421_00703;MGYG000003368_00166;MGYG000004564_01656;MGYG000003868_01165 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CYTB@85004|Bifidobacteriales 0.4 186801|Clostridia 0.4 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 0.6 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000004535_00736 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 821365 0 0 0 1078215 0 0 0 558221 579373 0 789223 0 0 928606 0 0 0 0 0 456281 0 1456128 0 0 0 0 0 0 941223 1417632 0 0 0 0 0 0 0 920186 0 0 0 927438 0 0 0 878678 980677 0 2015828 0 0 1094894 0 1727529 0 0 0 620032 632270 1203952 0 0 0 1541382 928611 0 975976 419897 0 0 0 0 0 0 0 644483 0 0 0 0 0 0 0 0 407015 0 640836 0 0 1138025 0 0 0 0 0 732579 0 0 0 0 0 0 0 0 631959 831215 0 0 0 0 0 0 0 0 0 0 0 884708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 945261 0 998039 0 0 0 0 529299 0 0 194152 0 0 0 0 0 0 0 0 0 0 0 148102 0 0 0 0 0 0 0 0 0 320806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QADKYKVPR MGYG000002218_02522 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides sp000436495|m__MGYG000002218 1.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia,22W0K@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000002218_02522 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 986536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228190 0 0 0 0 0 0 0 167339 0 323152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47215 0 0 0 0 0 0 0 696282 0 531637 0 0 0 0 0 0 0 0 0 0 0 0 509973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 586657 0 0 0 0 0 0 0 179035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249259 0 0 0 0 0 0 0 1637845 0 258626 0 0 0 0 0 0 0 0 0 0 0 0 557342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3059650 0 0 0 0 0 0 +(Gln->pyro-Glu)QADKYNVPR MGYG000002549_02927;MGYG000002900_01695;MGYG000001489_02612;MGYG000001659_00198;MGYG000001783_02408;MGYG000002203_01145;MGYG000004536_01502;MGYG000002007_02083;MGYG000003693_00191;MGYG000001763_00795;MGYG000003680_01539;MGYG000001302.1_01164;MGYG000004885_00623;MGYG000002293_00507;MGYG000000138_02891;MGYG000000118_01086;MGYG000002478_00801;MGYG000001599_01853;MGYG000000562_01882;MGYG000002275_02119;MGYG000000696_01665;MGYG000000243_01973;MGYG000000044_03026;MGYG000001364_02756;MGYG000004569_00159;MGYG000002603_01769;MGYG000004763_00924;MGYG000002281_02277;MGYG000001770_00611;MGYG000000003_00089;MGYG000002580_00548;MGYG000001346_01521;MGYG000004006_01224;MGYG000001415_01615;MGYG000002561_02173;MGYG000001306_02658;MGYG000001835_01810;MGYG000004756_01926;MGYG000004456_02002;MGYG000003353_00672;MGYG000003701_04692;MGYG000003363_02293;MGYG000000215_01916;MGYG000003926_00227;MGYG000000187_02028;MGYG000000196_03987;MGYG000000825_01836;MGYG000000272_00847;MGYG000004638_00290;MGYG000002438_02206;MGYG000000042_01093;MGYG000001314_02081;MGYG000000174_03528;MGYG000001806_01478;MGYG000002834_00438;MGYG000001337_03891;MGYG000000074_01964;MGYG000001546_01215;MGYG000003355_03290;MGYG000004464_01245;MGYG000001360_01215;MGYG000003546_00261;MGYG000000098_02004 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia,4AKVK@815|Bacteroidaceae 0.30158730158730157 976|Bacteroidetes 0.8888888888888888 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 0.9841269841269841 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000002549_02927 0.015873015873015872 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 6254765 7363239 12577860 6324136 10545103 6830970 6588157 6552292 5878790 5988228 7764208 6249003 12732584 8669085 7057976 13615994 8074242 5433733 6197160 6391714 6510969 5305931 4164645 6750760 6365283 6807161 6761447 5032346 6868196 8195968 7231493 8761855 10928324 5930204 7895762 5584809 6090520 9790917 5670540 3774971 6354245 5486318 6741205 4765452 4083897 6545828 5992565 6203234 8200914 5766679 12214522 5971181 5505432 7036808 4819207 4238434 5168168 4844226 5163937 4497570 8451707 3432437 5249762 6227649 7060863 7539367 5039420 6115647 5157291 6041700 5123311 5967305 7021963 5613613 5770505 5619111 3837200 4116036 6823985 4073845 8177829 6431644 4667644 4088669 5734056 3560312 5517558 4457083 6720870 4598108 3528116 6275011 4523552 0 4578156 3522555 4021766 3278978 4082748 4098525 5035750 4012201 4301556 0 3956652 4273596 4651206 3549176 3908909 3702175 4360634 6844639 4961439 4573748 5014317 4781603 8550580 4078920 7098925 8598277 5544420 6524555 5175510 6471187 11110963 7811108 10067044 4944735 5940913 8347625 4893845 10155543 5311663 4063238 4488257 11757660 8693784 9469770 8653493 8270253 5289929 9406138 5961325 4831047 6137230 7112174 7734477 5879028 6116705 5436888 6365674 8954836 3958650 3663934 3952591 6431212 7620721 7214934 4608726 5082143 5527399 5141833 7458249 6597231 11803491 3621523 4342827 8399492 5029227 6313439 5217880 6405562 6072485 4683146 6447493 5485257 5098170 8211252 4436708 4645769 4467580 8350288 6046556 5609888 4031919 5542315 5996109 5791124 7631822 5901036 +(Gln->pyro-Glu)QADREGYPEIAEAFKR MGYG000000170_00133;MGYG000001655_01235;MGYG000004830_00759;MGYG000001302.1_00876;MGYG000001641_00704;MGYG000004468_01487;MGYG000001599_02598;MGYG000000243_02810;MGYG000000215_01429;MGYG000003992_02545;MGYG000002171_00343 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1592@1|root,COG1592@2|Bacteria,4NJ7V@976|Bacteroidetes,2FP1G@200643|Bacteroidia,4AKVP@815|Bacteroidaceae 0.45454545454545453 976|Bacteroidetes 0.9090909090909091 C 0.9090909090909091 Psort location Cytoplasmic, score 8.96 0.5454545454545454 rbr3A 0.9090909090909091 - 1.0 - 1.0 - 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 1.0 - 0.9090909090909091 - 1.0 - 1.0 - 1.0 Rubrerythrin 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000170_00133 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 0.9090909090909091 none 1.0 450380 654644 1720793 0 1001072 599237 0 811930 0 515911 0 0 782969 659348 0 787897 797307 0 0 0 0 541148 0 626698 0 571069 0 0 0 0 1081808 760309 1566766 0 0 568454 515898 1467985 246975 0 323021 0 230437 0 0 168749 0 299926 0 0 0 369406 0 0 0 0 0 0 0 0 0 0 0 352394 0 0 0 0 0 0 0 0 0 142629 145776 165378 256299 340505 345498 0 230520 324974 0 375370 0 192351 0 0 286724 97126 0 262098 110612 0 0 0 0 187608 0 181424 0 179852 0 0 0 0 218398 229232 211656 0 0 111884 352603 0 243302 0 254297 0 136455 96936 0 235436 0 253498 0 0 0 96572 0 0 470458 0 0 0 0 0 0 213573 0 141788 0 0 0 0 0 105630 189456 0 0 709258 244827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190362 0 0 0 0 0 0 0 0 0 115342 348424 0 0 0 189520 0 +(Gln->pyro-Glu)QADREGYPEIAEAYKR MGYG000000272_02992;MGYG000002293_00120;MGYG000003467_00199;MGYG000001770_01423;MGYG000000074_02407;MGYG000002080_02179;MGYG000001546_02758;MGYG000002834_02175;MGYG000003697_00652;MGYG000000003_01138;MGYG000002960_00848;MGYG000002603_00556 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1592@1|root,COG1592@2|Bacteria,4NJ7V@976|Bacteroidetes,2FP1G@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 0.6666666666666666 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000272_02992 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 430637 0 460566 302936 0 293237 198942 0 354548 496581 0 307727 0 450892 0 0 416832 0 0 0 0 0 0 299773 411920 295660 450568 0 202879 0 224666 330099 0 193409 0 0 224687 0 324756 0 307219 423951 0 0 295250 0 0 406721 0 0 0 189678 326169 0 0 0 0 0 0 300764 0 262976 154115 308362 0 0 341883 0 243673 0 145345 0 413720 0 0 250659 0 0 0 0 0 0 0 205238 180194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340359 0 0 0 0 0 0 0 270782 0 0 0 0 1144610 1712515 2132362 1409481 1690768 2403875 1708065 1569896 1473972 2094541 2063855 2085237 1889864 1060801 1638113 1412130 1372704 3182500 0 1219714 0 2410216 5581167 1866035 1480327 1510270 1336108 5778816 2195619 0 2529936 2255846 1585702 1932676 2160522 0 1308254 2127244 0 175553 360845 723202 236031 272157 231169 0 0 334675 102713 0 565517 108852 0 0 220485 0 0 296341 0 0 0 0 253265 194365 249754 0 0 0 390658 532598 381144 0 262843 0 645667 0 +(Gln->pyro-Glu)QADREGYPEVAEAFKR MGYG000002438_03105;MGYG000004797_02618;MGYG000000042_00595;MGYG000001489_02852;MGYG000002281_03982;MGYG000001461_01112;MGYG000003351_03597;MGYG000001644_00337;MGYG000002455_02720;MGYG000002133_01221;MGYG000000098_01044;MGYG000000174_01697;MGYG000002291_00592;MGYG000000222_03431;MGYG000001345_01982;MGYG000002933_00579;MGYG000000196_00855;MGYG000002478_02503;MGYG000002561_03555;MGYG000003312_01033;MGYG000000696_01296;MGYG000003221_02337;MGYG000002549_01165;MGYG000001306_02407;MGYG000001337_03530;MGYG000000781_01988;MGYG000000236_00566;MGYG000001378_03535;MGYG000000054_03085;MGYG000001920_02116 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1592@1|root,COG1592@2|Bacteria,4NJ7V@976|Bacteroidetes,2FP1G@200643|Bacteroidia,4AKVP@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 0.8333333333333334 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03105 0.03333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1292237 1310253 1735761 1603237 1731234 1611441 1672222 1554287 1611126 1482968 1578913 1347616 1884316 1835401 1376470 2037229 1813875 1472309 1498229 1253108 1484169 1669046 1264257 1764040 1416652 1656651 1464313 1638348 1436588 2290409 1914592 1822517 1627691 1498296 1631457 1487090 1533958 1352619 1188404 942670 1191171 1245680 1427817 1214747 945093 1074134 1101686 1785540 1653142 1449146 1628322 1502308 1522363 1517167 1513627 723391 1037230 617139 1194078 1385680 946128 863120 1495598 1267550 1208003 1009352 1306604 1431956 932615 1631078 736674 1133441 1150271 1034108 1139753 989036 1138213 1344320 1312199 997544 1502537 1830469 984760 1216452 1196380 1231855 1323152 1696418 1461203 1239970 1064404 1268063 1018326 1758436 1035566 837557 1077765 949740 1607437 1190375 1230019 1136129 1593432 1489853 1268639 1079731 1307479 1086708 960696 977786 1308970 1268270 1249636 1016553 2474428 0 1054562 1990011 0 1701716 0 0 2839106 0 1226402 2079445 1572884 1974211 2761810 1569961 0 1083629 0 2044145 2452496 1017601 1849215 1050246 3307538 2309643 2239097 1319087 1385737 0 1144719 0 1150609 0 0 0 2138076 955592 1071318 1001715 1158501 1652946 1969752 1811725 1111030 1342587 1636085 1200926 1675421 1464949 2342869 867210 1393142 1714538 1474222 1232394 1261085 1234890 1279461 1239152 1239575 1251109 1126222 1382420 1053076 1397747 1322781 1921891 1475258 2067227 1005451 1501589 1893880 1080642 1850665 1550758 +(Gln->pyro-Glu)QADRQDFNHIPAAQWVITK MGYG000002438_01810 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 435591.BDI_2723|- 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01810 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 201079 0 313182 0 0 0 0 0 0 0 0 0 0 1783562 0 0 0 0 0 0 1979082 0 0 0 0 0 0 0 0 3384124 0 0 0 0 0 0 0 0 3012623 0 2479323 0 0 0 0 0 0 +(Gln->pyro-Glu)QADTYNVPR MGYG000001615_01715;MGYG000000080_02057;MGYG000000171_02843;MGYG000002279_01931;MGYG000000201_03874;MGYG000000417_00151;MGYG000003013_00348;MGYG000004735_00885;MGYG000002966_00551;MGYG000001688_04230;MGYG000001714_01290;MGYG000001311_05179;MGYG000000271_03364;MGYG000000038_00759;MGYG000001367_00668;MGYG000000133_02992;MGYG000001315_01206;MGYG000003702_00714;MGYG000004380_01409;MGYG000000262_00029;MGYG000001707_01475;MGYG000001379_00688;MGYG000000198_01164;MGYG000001310_01964;MGYG000000077_01356;MGYG000002528_01099;MGYG000000263_00835;MGYG000000179_00921;MGYG000002312_02892;MGYG000001710_02264;MGYG000000216_02407;MGYG000002517_00204;MGYG000001186_01601;MGYG000000909_01303;MGYG000002298_03446;MGYG000000028_00227;MGYG000001531_00907;MGYG000001607_01044;MGYG000004296_01667;MGYG000001637_00070;MGYG000000278_00903;MGYG000003366_00387;MGYG000001338_03374;MGYG000000251_00063;MGYG000000142_00172;MGYG000000233_00808;MGYG000000204_00533;MGYG000000200_01983;MGYG000000050_01748;MGYG000000146_01349;MGYG000000242_00283;MGYG000001303_01923;MGYG000000255_02008;MGYG000004891_02430;MGYG000004087_00550;MGYG000000164_01097;MGYG000000212_03312;MGYG000001374_01219;MGYG000000154_02190;MGYG000002946_01538;MGYG000001777_01731;MGYG000004271_02230;MGYG000002212_00197;MGYG000000249_00027;MGYG000000002_03595;MGYG000001319_01765;MGYG000001496_01735;MGYG000002492_00343;MGYG000001617_01407;MGYG000004359_00697;MGYG000000127_03983;MGYG000000206_00900;MGYG000004733_01212 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.3013698630136986 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 0.9863013698630136 MGYG000001615_01715 0.0136986301369863 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 1585509 1952785 2009196 1185705 2244115 1967823 909711 2323591 1431719 2295913 2161715 2117000 2393611 1726787 2027973 2027712 1620361 2552612 1580177 1802933 1600322 2286267 1704583 892360 2264527 1572864 1538152 2346512 1481460 1717002 769715 1821676 969400 1523367 1555407 1154136 1256819 1084268 1819282 2717345 303432 1883211 1607438 0 1896501 1625805 1279595 1619410 1329247 1025010 1536900 1427800 967972 1021724 607245 2258878 725020 1864905 1427036 0 1686567 1852894 1648668 1458267 2057188 2468010 2359945 1627276 2896932 1825283 1212885 1733476 1773494 1674671 1330711 1365668 1737050 2530187 1741277 1982884 694638 1091249 1070185 1788912 1082418 1617651 1227565 1148344 1762096 1812004 1884493 1967793 1821920 741867 1515769 1452767 956951 2449460 1192254 912057 1627730 1403595 2205573 2343851 1682689 1327029 1115925 2545335 2048462 1723974 2143949 876227 1361894 1541927 1769405 1772609 1325116 1888904 1471367 951140 1284895 2183244 1983707 1612224 1347829 1449615 1898194 1806488 2041704 1430884 1931094 941783 1674820 2092890 1520801 1210250 966007 1375852 1957797 1853536 2072255 1330279 1928738 1821105 1724320 1670152 198923 1362903 1836833 1556916 1929771 1532034 917267 1280467 2562840 1499442 940958 1754051 2157325 1259800 1615931 3121902 1994046 2058829 1127791 2708873 1630129 1515756 1874210 715831 1606534 1022250 2286481 1085301 1238105 2124013 2768518 1943059 2679799 1373873 1619125 1048204 2146794 445992 6045583 2217282 370111 2764860 2924802 2705129 +(Gln->pyro-Glu)QAEAAAEAAEKDAVK MGYG000000179_03470 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 29UBJ@1|root,30FMY@2|Bacteria,1UE9B@1239|Firmicutes,25J4K@186801|Clostridia,22109@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03470 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 549623 0 1042948 416488 1119324 0 0 0 573397 0 582616 0 0 413514 399519 0 226581 0 384373 470044 0 482544 0 782737 0 413854 423398 0 610974 266725 212725 0 1444482 326797 0 360565 420914 1709501 0 0 0 0 0 0 0 0 234694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139320 0 0 0 0 482843 0 397984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324304 0 0 0 0 155350 0 0 0 0 814342 0 807758 0 541154 366605 0 0 391809 0 0 0 0 0 0 0 932952 0 558788 0 0 0 0 806660 0 460333 716479 0 902441 0 807862 0 914178 0 0 404653 621863 497894 1929822 0 793489 1672108 1361394 1123973 0 0 1744356 1417434 971624 0 0 1378371 1797786 0 2208449 0 1704572 2522579 0 945076 0 1588281 0 2151445 1237278 0 2350283 1852489 1177743 0 911297 1297169 0 1301661 2175376 1324428 +(Gln->pyro-Glu)QAEAAAESAEKDAVK MGYG000000198_04357 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 29UBJ@1|root,30FMY@2|Bacteria,1UE9B@1239|Firmicutes,25J4K@186801|Clostridia,22109@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04357 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 542572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 844409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133787 273081 0 0 0 0 0 405050 0 0 0 0 0 0 0 0 318008 455536 0 839135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472281 1411137 0 0 0 0 820309 754187 0 0 0 0 0 0 0 0 637597 446773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252188 0 0 +(Gln->pyro-Glu)QAEADKYAAQQR MGYG000002517_02730 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,247MK@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 SPFH Band 7 PHB domain protein 1.0 - 1.0 - 1.0 - 1.0 ko:K07192 1.0 ko04910,map04910 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03036,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Band_7,Flot 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02730 1.0 - - - - 1.0 1.0 1.0 1.0 Insulin signaling pathway 1.0 K07192:FLOT; flotillin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 556475 0 0 793023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 808047 0 0 0 0 0 0 0 0 0 0 581647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166368 0 0 0 0 0 0 0 0 0 0 631974 0 +(Gln->pyro-Glu)QAEAETQTASGLFIPDNAK MGYG000003452_00101;MGYG000000756_01001;MGYG000003683_01174 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4D101@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003452_00101 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04078:groES, HSPE1; chaperonin GroES 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 288032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325204 0 0 0 0 0 0 1148530 0 0 0 0 834542 0 0 0 503106 820724 794243 0 0 0 906463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAEAIVAEAK MGYG000000198_04357;MGYG000000179_03470 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 29UBJ@1|root,30FMY@2|Bacteria,1UE9B@1239|Firmicutes,25J4K@186801|Clostridia,22109@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04357 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 329991 0 362665 0 0 0 0 0 116559 0 0 0 0 0 0 0 0 0 615263 287815 0 606399 0 0 0 112569 241385 0 0 226260 0 0 588638 0 0 339149 0 431810 0 0 165718 0 0 305161 0 0 0 170473 0 0 0 0 0 0 0 0 98035 308692 0 131052 0 404664 0 0 485266 0 0 304964 0 0 0 0 0 0 313758 614397 353862 0 0 0 0 0 0 0 218369 98107 0 0 0 0 226362 0 0 0 191897 223773 0 0 0 0 0 391607 241821 0 0 0 0 0 0 227927 0 375676 0 138679 0 0 0 0 0 0 0 0 296358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144530 0 0 548423 0 429047 0 0 305132 0 0 869221 673561 0 0 0 0 704777 0 0 0 514784 825020 0 581337 0 844043 0 1172033 848599 0 0 832559 0 0 429657 566292 0 691638 901279 1126392 +(Gln->pyro-Glu)QAEAQTQTASGLYIPDNAK MGYG000001292_02387 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4D101@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001292_02387 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04078:groES, HSPE1; chaperonin GroES 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 884534 0 0 0 0 679578 0 0 0 0 1176554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAEENAKEK MGYG000000080_02732 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000080_02732 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994041 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAEGM(Oxidation)SWAAEHVVGVAK MGYG000000133_01999 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01999 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 945194 1396768 904828 1581183 0 1033660 1233128 0 1092055 1570974 2167714 1224358 2689413 1408206 1119823 1206185 922935 0 1278995 0 994836 1118750 0 851733 1360303 1207900 928511 0 1484914 0 963790 2674063 1998184 1487818 0 1054552 1505782 963530 +(Gln->pyro-Glu)QAEGMSWAAEHVVGVAK MGYG000000133_01999 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01999 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 307761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493462 0 0 0 0 0 952362 0 0 0 0 0 0 0 0 0 0 0 225185 0 0 0 0 0 0 1293449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2244397 2576309 2069293 4298426 773291 1779826 2781861 1526042 1972632 3120105 4053770 2140208 3599913 3224314 2269983 1831202 2444026 0 2348052 0 2316070 1153705 0 1469485 2290372 2455538 2271018 0 3401261 0 2353395 4594362 3523885 2255138 1936350 2235906 2019528 1958200 +(Gln->pyro-Glu)QAEGNVLVPYR MGYG000000074_01523 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,22UVQ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01523 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 749237 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAEVHGMSQR MGYG000001787_00875;MGYG000000222_02316;MGYG000004479_01009;MGYG000004823_02546;MGYG000002935_02200;MGYG000003521_00869;MGYG000002438_02777;MGYG000003223_00829;MGYG000004006_01367;MGYG000003469_01108;MGYG000000354_01226;MGYG000001337_02097;MGYG000000044_02502;MGYG000002418_00346;MGYG000001302.1_02330;MGYG000004464_01478;MGYG000004797_03431;MGYG000003542_00040;MGYG000001750_01691;MGYG000003922_02594;MGYG000001661_02375;MGYG000002291_01399;MGYG000001562_00082;MGYG000002561_02121;MGYG000003351_04377;MGYG000000236_04030;MGYG000000224_02646;MGYG000002540_02695;MGYG000000074_00929;MGYG000003681_01658;MGYG000001346_02972;MGYG000003367_02059;MGYG000001420_02103;MGYG000003429_00309;MGYG000000415_00752;MGYG000000042_01640;MGYG000000003_01691;MGYG000003546_02127;MGYG000000355_01069;MGYG000001372_02690;MGYG000004573_01499;MGYG000000196_04785;MGYG000004468_01092;MGYG000002203_00473;MGYG000001780_04576;MGYG000003908_01857;MGYG000004853_01517;MGYG000003282_00166;MGYG000003363_02416;MGYG000000243_02435;MGYG000001666_01146;MGYG000002171_00872;MGYG000001789_00914;MGYG000000437_01559;MGYG000000170_01475;MGYG000001641_02232;MGYG000002082_01821;MGYG000001378_04698;MGYG000001783_01848;MGYG000000105_00772;MGYG000002560_03681;MGYG000004763_00180;MGYG000002478_02411;MGYG000000098_01750;MGYG000003353_02100;MGYG000004658_00043;MGYG000002218_02977 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1014@1|root,COG1014@2|Bacteria,4NGN3@976|Bacteroidetes,2FP78@200643|Bacteroidia,4AM9G@815|Bacteroidaceae 0.47761194029850745 976|Bacteroidetes 1.0 C 1.0 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin 0.5522388059701493 iorB 0.9552238805970149 - 1.0 1.2.7.8 1.0 ko:K00180 0.9552238805970149 - 1.0 - 1.0 - 1.0 - 1.0 br01601,ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 POR 0.9552238805970149 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001787_00875 0.014925373134328358 indolepyruvate ferredoxin oxidoreductase. IOR. Preferentially utilizes the transaminated forms of aromatic amino acids and can use phenylpyruvate and 4-hydroxyphenylpyruvate as substrates.-!-This enzyme, which is found in archaea, is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = (indol-3- yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K00180:iorB; indolepyruvate ferredoxin oxidoreductase, beta subunit [EC:1.2.7.8] 0.9552238805970149 none 1.0 1031580 0 0 0 0 0 0 837291 0 0 0 0 0 0 0 0 0 1089418 0 0 0 0 738309 0 0 840234 0 793565 0 0 0 0 0 0 0 0 775674 0 770759 0 0 0 0 0 0 666258 0 0 0 0 0 0 0 0 0 400969 0 0 0 0 580105 0 0 508059 0 263869 0 0 0 0 0 0 0 0 754569 0 664992 0 0 0 0 0 0 785975 0 0 0 0 0 0 0 0 0 713161 0 0 0 0 743440 0 0 594449 0 672831 0 0 0 0 0 0 0 0 829329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454162 0 562561 0 0 0 0 0 0 1149009 0 0 0 0 0 0 0 0 0 178472 0 0 0 0 849392 0 0 1298680 0 782095 0 0 0 0 0 0 0 0 1191174 0 +(Gln->pyro-Glu)QAFGDTLVEDHK MGYG000001157_01264;MGYG000003921_00349 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 1.0 rpsC 1.0 - 1.0 - 1.0 ko:K02982 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001157_01264 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02982:RP-S3, rpsC; small subunit ribosomal protein S3 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 419392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAFHGLYR MGYG000002080_00556;MGYG000001056_02471;MGYG000003493_00796;MGYG000003697_01453;MGYG000000272_00830;MGYG000002293_00490;MGYG000002834_00455 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,2FNEG@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center 1.0 rplF 1.0 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02933 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002080_00556 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02933:RP-L6, MRPL6, rplF; large subunit ribosomal protein L6 1.0 none 1.0 262637 485186 0 260407 0 0 0 0 427362 544871 542476 499192 634734 313109 0 107757 383980 0 446270 166670 0 0 178841 707881 398510 693939 484772 394279 0 0 0 395053 564871 413354 0 121338 0 0 0 0 0 0 0 0 0 0 0 0 196017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365794 0 0 0 210237 0 0 0 0 0 403480 0 0 0 0 0 0 0 149347 0 0 0 0 0 0 0 0 0 0 0 0 242838 0 1136626 1374221 4975008 1026823 2667202 3907021 0 1402575 1135726 1190458 4829576 1491282 4234369 1011975 1367539 2518245 1186094 2585048 1024931 941994 0 4400436 4389628 4539297 1467696 1382987 1322091 3266611 0 0 0 1886812 4301484 1387943 1360548 1265966 1168288 5040379 0 0 0 0 0 0 0 0 0 0 97286 0 0 0 0 0 0 423371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253071 0 280984 0 0 +(Gln->pyro-Glu)QAFTQVKIEK MGYG000000271_00118 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 - 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00118 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02888:RP-L21, MRPL21, rplU; large subunit ribosomal protein L21 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAGDNIGALLR MGYG000001615_01716;MGYG000000171_02844;MGYG000004732_02398;MGYG000002279_01932;MGYG000000385_01364;MGYG000000201_03875;MGYG000000245_03248;MGYG000001688_04229;MGYG000003063_00662;MGYG000004735_00884;MGYG000000280_01200;MGYG000004893_01944;MGYG000000198_01165;MGYG000004893_00932;MGYG000002563_00522;MGYG000001507_06245;MGYG000001315_01207;MGYG000000410_01314;MGYG000000133_02991;MGYG000001602_02247;MGYG000003937_01027;MGYG000001310_01963;MGYG000003273_00234;MGYG000000140_01590;MGYG000001404_04883;MGYG000001623_00993;MGYG000003142_01879;MGYG000002528_01098;MGYG000002202_00030;MGYG000001436_02249;MGYG000001525_00035;MGYG000002563_00509;MGYG000000157_01091;MGYG000001619_01314;MGYG000000179_00920;MGYG000000216_02406;MGYG000000217_01428;MGYG000002517_00205;MGYG000000173_00405;MGYG000002290_01325;MGYG000004296_01668;MGYG000001607_01045;MGYG000001141_02439;MGYG000002059_00460;MGYG000003142_01865;MGYG000000024_03409;MGYG000001652_01300;MGYG000003425_03741;MGYG000000251_00064;MGYG000001338_03373;MGYG000002670_00364;MGYG000000139_00697;MGYG000000233_00807;MGYG000000142_00171;MGYG000000255_02009;MGYG000000349_00457;MGYG000000404_00531;MGYG000004087_00551;MGYG000000084_02000;MGYG000000164_01096;MGYG000000018_00453;MGYG000002126_00299;MGYG000001299_01777;MGYG000002234_01026;MGYG000001606_01669;MGYG000000202_03457;MGYG000001698_04050;MGYG000000212_03313;MGYG000002105_00002;MGYG000001359_01254;MGYG000002224_01123;MGYG000002950.1_00050;MGYG000002837_02416;MGYG000000193_02083;MGYG000002212_00196;MGYG000000249_00026;MGYG000004799_01385;MGYG000004630_01824;MGYG000000501_01307;MGYG000002286_02469;MGYG000001814_01592;MGYG000000262_00030;MGYG000003486_01055;MGYG000003073_01160;MGYG000002772_01895;MGYG000002492_00344;MGYG000001617_01406;MGYG000002596_02296;MGYG000003921_01124;MGYG000001712_00119;MGYG000003620_01283;MGYG000000206_00901;MGYG000004733_01211 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 0.1827956989247312 186801|Clostridia 0.8387096774193549 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.946236559139785 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.946236559139785 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001615_01716 0.010752688172043012 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 128054 229974 0 66750 155715 0 432508 320892 250985 0 185211 95458 0 0 190504 75075 109381 0 199220 111454 83499 1073764 189968 0 0 0 670176 93765 0 263958 0 0 0 178946 0 0 172653 0 0 0 0 0 0 0 85793 0 197435 0 0 88280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81520 0 52849 0 0 0 0 321937 0 420821 615145 0 135119 340057 0 482282 554428 355299 0 575646 481659 0 0 459177 420395 0 0 174707 389166 114111 0 0 0 0 0 0 0 0 346034 0 576092 576433 444689 0 0 297742 0 591247 269640 0 506412 488632 0 459471 313310 526600 0 265924 688371 0 0 521513 745103 159790 0 516086 0 191957 500168 453635 0 0 0 608425 799239 0 713572 0 658223 0 630518 0 0 565561 0 0 0 0 65200 0 0 0 103002 114332 0 192516 236116 0 0 0 0 0 0 231623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAGDSVKEEALR MGYG000000089_01181 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000089_01181 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405036 0 0 0 0 580845 0 0 0 0 404605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAGIVDPAKVER MGYG000002834_01380;MGYG000000272_02397;MGYG000001056_01919;MGYG000003697_01689;MGYG000002293_01257;MGYG000001770_01876;MGYG000002080_00257 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 0.5714285714285714 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002834_01380 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 278010 0 0 336280 0 0 479298 0 0 0 0 0 0 758008 0 0 0 411179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 171529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2693948 0 2014729 2268005 0 1846564 0 0 2779039 0 1544157 0 0 0 0 3962628 0 0 0 1938359 5677107 2095411 0 0 0 4317898 0 0 2456615 0 2397097 0 0 0 0 3051486 0 0 0 0 695735 0 0 0 0 0 468460 0 362635 0 0 0 0 278538 0 0 0 0 485092 549864 0 0 0 421284 0 0 0 0 0 0 0 0 0 428594 +(Gln->pyro-Glu)QAGVVDSGGQGLMQVMK MGYG000000255_00270;MGYG000000087_00334;MGYG000002517_01429;MGYG000000233_01627 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,21XXP@1506553|Lachnoclostridium 0.75 186801|Clostridia 1.0 S 1.0 Dak1_2 0.75 - 1.0 - 1.0 - 1.0 ko:K07030 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Dak1_2,Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_00270 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07030:fakA; fatty acid kinase [EC:2.7.2.18] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 506280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAHWNMR MGYG000002506_00089;MGYG000002323_01394;MGYG000002494_00829;MGYG000002515_00914 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,1RR4N@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 P 1.0 During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction 1.0 dps 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005623,GO:0006950,GO:0008150,GO:0008199,GO:0009289,GO:0009295,GO:0009605,GO:0009991,GO:0031667,GO:0042594,GO:0042802,GO:0042995,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0097159,GO:1901363 1.0 - 1.0 ko:K04047 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03036 1.0 - 1.0 - 1.0 - 1.0 Ferritin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00089 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04047:dps; starvation-inducible DNA-binding protein 1.0 none 1.0 1161188 1145549 908182 998006 1300515 1977058 1784745 2224831 1260371 2170057 91161 1149328 0 1674161 1008001 601449 845014 0 1216459 1181896 1353634 1546428 0 2238393 1526445 939112 1398662 0 1491733 1494220 0 974066 1035557 2310332 2098791 945632 945806 1073192 1858576 2027729 2134749 1976401 2045151 4516647 2500061 1435420 1685024 2792415 919198 1244809 0 1735912 2133585 884422 2031140 0 2739889 1662303 1741342 5227333 0 3654630 1701192 2052123 1547836 0 2395249 1691739 0 2159019 1721698 1806727 2141380 1646218 1589923 1571289 201531 0 493679 0 346734 1256472 516435 643211 308924 783558 251949 239351 0 357059 284221 498591 284885 0 506945 271776 340393 733858 0 851261 611702 158518 327683 0 0 510004 0 0 419452 740958 431662 320976 243594 302685 669856 840873 1167305 225576 301520 1213094 1507351 983234 784021 1409212 457049 441579 0 458187 700109 445123 697131 0 788756 740231 984783 2038184 0 1111601 1218274 967852 826596 0 260439 654834 0 255354 821796 1439712 1233156 874737 550772 716408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAIAESWPNSLDDTC(Carbamidomethyl)AR MGYG000000355_00183;MGYG000001364_03471;MGYG000004479_02858;MGYG000004797_02539;MGYG000003693_03216;MGYG000003701_03756;MGYG000000243_01845;MGYG000002171_01133;MGYG000002478_01472;MGYG000002438_03364;MGYG000000044_00200;MGYG000002218_02050 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 0.75 976|Bacteroidetes 1.0 GM 0.75 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000355_00183 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAIAEVEKAEQASA MGYG000000171_00103;MGYG000000201_01930;MGYG000002298_00783;MGYG000000212_00237 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3Y0GK@572511|Blautia 1.0 186801|Clostridia 1.0 U 1.0 COG COG1862 Preprotein translocase subunit YajC 1.0 yajC 1.0 - 1.0 - 1.0 ko:K03210 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2 1.0 - 1.0 - 1.0 Ftsk_gamma,YajC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_00103 0.25 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03210:yajC; preprotein translocase subunit YajC 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 854291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1148154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 826583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1243203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAIDGDTAQVGPQIAEK MGYG000003589_02741;MGYG000002926_00638;MGYG000003166_01337;MGYG000000016_02517;MGYG000002673_02002;MGYG000002610_00220;MGYG000002272_01494;MGYG000002086_01704;MGYG000004464_00649;MGYG000000177_02367;MGYG000003291_01729;MGYG000001157_00998;MGYG000001623_01849;MGYG000004271_00471;MGYG000004525_01509;MGYG000001356_00010;MGYG000003442_01120;MGYG000004863_01199;MGYG000003324_00158;MGYG000004679_00692;MGYG000003899_01133;MGYG000002057_00750;MGYG000000177_01042;MGYG000003770_01062;MGYG000000792_00568;MGYG000002105_00078;MGYG000002224_01330;MGYG000000354_00400;MGYG000000022_01321;MGYG000003498_00873;MGYG000004718_00706;MGYG000004196_00483;MGYG000001500_03164;MGYG000004276_00462;MGYG000000084_00626;MGYG000000099_01611;MGYG000002720_01505;MGYG000004866_01547;MGYG000001191_01318;MGYG000003937_01088;MGYG000002040_01718;MGYG000004489_00129;MGYG000002944_02006;MGYG000002619_02236;MGYG000001729_00006;MGYG000001300_00292;MGYG000004732_01391;MGYG000004482_00822;MGYG000002791_00492;MGYG000001643_03098;MGYG000000039_00174;MGYG000002274_00048 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WH8V@541000|Ruminococcaceae 0.4423076923076923 186801|Clostridia 0.9230769230769231 C 1.0 Psort location Cytoplasmic, score 0.5192307692307693 - 0.8076923076923077 - 0.9230769230769231 1.3.1.108 0.8269230769230769 ko:K03521,ko:K22431 0.8269230769230769 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 0.8269230769230769 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003589_02741 0.019230769230769232 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 0.8269230769230769 0.8269230769230769 0.8269230769230769 0.8269230769230769 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit|K22431:carD; caffeyl-CoA reductase-Etf complex subunit CarD [EC:1.3.1.108] 0.8269230769230769 none 1.0 2902150 3482514 3480259 3492128 2260496 2810106 2873677 3352543 3285871 3892182 2633420 2630853 3542117 3705241 4126819 2934673 3711207 2787264 4483766 3677617 2940443 3551365 2466438 3492361 4058095 3750086 3684758 2445870 2145697 3004976 2893881 2545360 3502715 4896400 3185274 3544663 3092593 3335689 3518359 3252953 3663096 4060651 2743682 4119354 4981966 2566909 3620722 1530109 2401667 4097704 2992426 3846544 4230288 2623498 3672936 2431154 4809496 3936009 2403001 2479550 2842447 3561968 5344554 3819402 4280600 2935099 1374409 3912988 4165628 3735370 3535103 3407218 1980711 2716772 3053232 3221657 1855845 0 1836525 1817773 1406249 1472268 1863529 1693607 1974431 1601119 2162137 2293470 1954830 1688798 1954324 1717196 1720334 1985927 1869900 1637972 1396526 0 2346456 0 1797618 2258707 1709245 2303327 1772998 2036042 1558280 0 1725558 2125630 1847456 1541438 1715725 1607843 2089526 2849292 4615949 2022662 3365504 3120998 3074752 1709774 3345885 3548252 3443092 3845944 3716536 2896927 2938787 2836401 2622365 2285020 4235019 2454588 2685344 2893851 3096220 2787656 2717137 2214235 2725399 2544503 2411594 3275270 3977354 3707692 4929621 4008407 2097189 2643519 3182844 4148144 767581 421420 985327 1162125 317956 735902 1156640 966808 1058683 834351 738657 1251380 660714 1176202 1139345 695053 826377 2060765 288796 394742 589292 313551 2388182 512881 891164 507010 791107 3024859 1119032 584772 975745 341201 1169844 786119 1171416 811807 826579 1168104 +(Gln->pyro-Glu)QAIDGDTAQVGPQLAEK MGYG000002105_00078;MGYG000003589_02741;MGYG000002926_00638;MGYG000000354_00400;MGYG000000022_01321;MGYG000003210_00606;MGYG000001191_00970;MGYG000003899_01133;MGYG000000084_00626;MGYG000003210_01741;MGYG000002791_00492;MGYG000004464_00649;MGYG000001191_01318;MGYG000001577_01511;MGYG000002274_00048 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WH8V@541000|Ruminococcaceae 0.3333333333333333 186801|Clostridia 0.8666666666666667 C 1.0 Psort location Cytoplasmic, score 0.5333333333333333 - 0.8 - 0.8 1.3.1.108 0.7333333333333333 ko:K03521,ko:K22431 0.7333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 0.7333333333333333 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002105_00078 0.06666666666666667 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 0.7333333333333333 0.7333333333333333 0.7333333333333333 0.7333333333333333 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit|K22431:carD; caffeyl-CoA reductase-Etf complex subunit CarD [EC:1.3.1.108] 0.7333333333333333 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1532562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2109497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1528839 0 1302325 0 0 0 0 0 0 0 1734975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1012223 0 0 0 0 0 0 +(Gln->pyro-Glu)QAIDGDTAQVGPQTAER MGYG000000223_02386 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,3VPI5@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_02386 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 780252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAIDGDTAQVGPQVAEK MGYG000001302.1_00862;MGYG000002438_02893;MGYG000004019_01436;MGYG000004797_03900;MGYG000001346_02513;MGYG000002281_01804;MGYG000003469_01113;MGYG000003701_04105;MGYG000002082_01219;MGYG000000462_00816;MGYG000000224_01763;MGYG000004711_01572;MGYG000000414_01885;MGYG000002033_00724;MGYG000000273_00875;MGYG000003279_00423;MGYG000001313_00857;MGYG000003420_00107;MGYG000001608_02430;MGYG000001364_02529;MGYG000002549_02817;MGYG000004876_02154;MGYG000004468_01621;MGYG000000196_04138;MGYG000003533_01230;MGYG000001750_01698;MGYG000003744_00979;MGYG000000696_01312;MGYG000001789_02010;MGYG000001783_00812;MGYG000003221_01663;MGYG000000348_00234;MGYG000001546_02765;MGYG000004006_00632;MGYG000000043_03473;MGYG000000053_01232;MGYG000001489_04896;MGYG000000355_01943;MGYG000002203_01949;MGYG000003312_03228;MGYG000004757_01583;MGYG000003367_00838;MGYG000001415_00121;MGYG000002561_01048;MGYG000004658_02629;MGYG000003693_03123;MGYG000004105_01672;MGYG000000243_00603;MGYG000004748_00349;MGYG000001503_00715;MGYG000000054_02440;MGYG000000074_02400;MGYG000004479_00382;MGYG000001306_03031;MGYG000001787_00188;MGYG000002933_02399;MGYG000001345_00398;MGYG000002218_00405;MGYG000001871_00778;MGYG000003952_01066;MGYG000000042_01534;MGYG000004536_00209;MGYG000001663_00335;MGYG000000098_00813;MGYG000001433_02399;MGYG000001562_02164;MGYG000001337_03724;MGYG000000781_02566;MGYG000000170_02403;MGYG000003282_00210;MGYG000000442_01089;MGYG000004756_00803;MGYG000004763_00383;MGYG000004899_00349;MGYG000003542_01688;MGYG000003164_01226;MGYG000001461_03959;MGYG000003423_01174;MGYG000000174_04854;MGYG000001429_00437;MGYG000001655_00932;MGYG000001420_01358;MGYG000003681_02881 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,4AN6T@815|Bacteroidaceae 0.46987951807228917 976|Bacteroidetes 0.9879518072289156 C 1.0 Electron transfer flavoprotein 0.4939759036144578 etfB 1.0 - 0.9879518072289156 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 0.9879518072289156 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_00862 0.012048192771084338 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 472267 0 895584 549147 781481 641110 471456 592975 754668 691442 635717 590109 700159 654956 792653 759990 447321 0 625173 554911 724760 573211 0 784145 628728 618365 582601 274865 421651 778918 772322 631201 853240 0 617809 759693 444165 756968 618359 0 789619 752121 806660 635817 691238 814178 640236 757252 798353 828263 558620 699143 762789 614212 580543 488838 666199 693805 624047 592753 783832 475225 776049 748519 732623 583999 789461 822226 464008 666490 639726 0 600498 480854 724715 604114 273359 0 607211 0 728176 353688 562852 463032 570378 345431 506323 502252 441729 438215 348529 379874 335594 425828 343659 0 351983 0 479696 649916 374899 299143 458731 550004 571063 359592 525935 433990 414494 0 323395 423049 430794 577761 392651 0 478052 0 354059 457066 533902 543614 427658 480720 177928 614819 458434 491336 0 370932 371764 0 386450 0 452253 0 0 0 402831 521689 430301 0 493239 334103 457269 606863 0 0 515870 502054 518462 0 386547 0 777827 1032690 1150168 640088 732201 797647 850769 615737 533474 708677 952428 442601 684911 683755 908062 850048 993016 1110265 602326 617951 896928 787702 714882 663090 598910 536450 677189 1029369 455610 861310 368213 0 318866 620076 806967 717473 +(Gln->pyro-Glu)QAIENKPGAPLK MGYG000002279_01084 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena_B|m__MGYG000002279 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24AN3@186801|Clostridia,27WHN@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 RnfC Barrel sandwich hybrid domain 1.0 prdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,RnfC_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_01084 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAIHVTK MGYG000000243_00262 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00262 1.0 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K00008:SORD, gutB; L-iditol 2-dehydrogenase [EC:1.1.1.14] 1.0 none 1.0 0 0 0 0 2733055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAIHVTKK MGYG000000243_00262 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00262 1.0 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K00008:SORD, gutB; L-iditol 2-dehydrogenase [EC:1.1.1.14] 1.0 none 1.0 0 1032241 0 0 1729694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1374009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAILDAAVANR MGYG000004797_01413;MGYG000002478_01739 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01413 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 301376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAILVEPK MGYG000002293_01420;MGYG000003697_02155 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01420 0.5 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K00008:SORD, gutB; L-iditol 2-dehydrogenase [EC:1.1.1.14] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107321 0 0 1193840 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 806560 0 0 0 0 1238252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAISKDNSADADYLR MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00133 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1017769 1197539 1588899 1141487 0 0 1130172 0 817784 0 866860 878113 520873 1119946 512964 0 1378723 0 504974 1261253 0 0 0 1089190 514507 557983 507109 0 1072809 1178235 0 770725 0 0 1100544 0 915053 0 178930 380983 501862 367283 602802 278260 346936 362766 478017 759066 549325 357669 464857 497604 671458 429539 449952 0 590578 588098 306697 263373 0 262923 442902 430324 689460 0 624291 413953 360650 809304 512437 0 624695 377206 509172 462155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690117 376046 685951 483068 739528 635887 557843 980223 690562 696109 343913 582691 499791 756018 850875 431884 431474 0 1041875 699500 420144 0 0 0 814786 825800 749080 0 637294 879374 453403 517549 554825 0 753786 667426 927944 469802 1929472 1534019 2478673 3835874 3323167 3494537 1785428 1281281 2328026 3996765 1853426 2599224 3220166 1740823 2203814 1982825 2994604 0 2786880 3223942 1705690 1832668 0 3055107 2053540 2499303 1911638 0 2199319 3356113 2307133 2942311 2083029 0 2462452 2454319 4496924 3315034 +(Gln->pyro-Glu)QAISYSYDRK MGYG000003891_00348 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG4166@1|root,COG4166@2|Bacteria 1.0 2|Bacteria 1.0 E 1.0 transmembrane transport 1.0 - 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 BACON,DUF4374,DUF4488,DUF5011,F5_F8_type_C,M60-like_N,Peptidase_M60,SBP_bac_5,Sulfatase,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_00348 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1636505 0 0 0 0 1481172 0 0 0 0 1477408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2241597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 912516 0 0 0 0 865974 0 0 0 0 439712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398287 0 0 0 0 762083 0 0 0 0 975056 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAITAAGSGC(Carbamidomethyl)K MGYG000004876_03337;MGYG000001345_01115;MGYG000002218_02990;MGYG000001370_01519;MGYG000001378_02367;MGYG000002455_05114;MGYG000000243_01362;MGYG000003351_01292;MGYG000003363_02359;MGYG000002171_00772;MGYG000001925_01350;MGYG000004797_00961;MGYG000003701_01280;MGYG000004479_01379;MGYG000000013_00650;MGYG000001306_03156;MGYG000002438_02820;MGYG000001783_01305;MGYG000002560_04136;MGYG000000042_00184;MGYG000002478_04055;MGYG000000355_01906;MGYG000001835_00791;MGYG000000098_03753;MGYG000003367_02255;MGYG000000174_04272 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia,4AM3W@815|Bacteroidaceae 0.8076923076923077 976|Bacteroidetes 1.0 C 1.0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004876_03337 0.038461538461538464 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 K00384:trxB, TRR; thioredoxin reductase (NADPH) [EC:1.8.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 329891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253870 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAITETGLIQGGEIK MGYG000000179_02302 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 299ND@1|root,2ZBPX@2|Bacteria,1UPWV@1239|Firmicutes,25HQW@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 L-2-amino-thiazoline-4-carboxylic acid hydrolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ATC_hydrolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02302 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 252625 0 365237 173692 348333 0 552429 0 687983 0 3800358 801787 376909 0 258253 592537 0 513708 210344 266640 0 0 401241 388285 153443 0 0 233888 304810 0 0 391591 0 240045 0 426180 250749 0 0 0 0 239269 0 0 0 0 0 0 0 330637 0 0 0 0 0 0 0 698032 0 0 0 0 0 0 0 0 411226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268756 135402 0 0 0 0 268127 0 0 0 280062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 654861 0 0 0 0 354569 0 0 0 0 0 0 0 0 0 0 0 511089 0 428340 0 311443 0 289945 0 0 0 0 0 1464349 943707 1190046 2368662 1348370 807228 0 854759 1510073 2401591 728409 1596406 1716850 2003064 1619978 758630 1876081 0 1327334 1731525 987844 1099908 0 982188 1382524 2236580 1470180 0 1661373 1306553 1216930 1769017 1366425 1306183 1068549 1314823 2036910 981297 +(Gln->pyro-Glu)QAITNPDNTVSSIKR MGYG000001300_00003;MGYG000002641_01428;MGYG000002619_01365 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3WGES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00003 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 267548 0 273416 0 0 278253 254715 0 285587 0 0 0 0 0 0 0 335254 0 0 0 0 243680 0 317719 0 0 0 0 0 0 0 0 361028 0 0 0 0 338882 792788 0 988318 0 0 793351 909788 0 897273 0 0 0 0 0 0 0 863873 0 0 0 0 554994 0 388328 919059 687701 0 0 0 0 0 0 937950 0 0 0 587726 799276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564333 520026 0 0 0 0 0 0 0 0 0 0 302597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAITNPENTVASIKR MGYG000002274_02128;MGYG000000022_02144 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3WGES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_02128 0.5 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1194610 0 0 0 0 1496314 0 0 0 0 1226210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1488331 0 0 0 0 2310145 0 0 0 0 1802413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1990956 0 0 0 0 1698003 0 0 0 0 1961286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 646502 0 0 0 0 884212 0 0 0 0 334913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660053 0 0 0 0 769936 0 0 0 0 828072 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAITNPKR MGYG000000074_02347;MGYG000001787_01989;MGYG000002007_00900;MGYG000004720_01456;MGYG000000941_00572;MGYG000003279_01430;MGYG000000003_01212;MGYG000001789_02778;MGYG000001302.1_00819;MGYG000001562_02334;MGYG000001420_01443;MGYG000003202_00959 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,22UA3@171550|Rikenellaceae 0.5833333333333334 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02347 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAITNPQR MGYG000000098_00251;MGYG000000243_00100;MGYG000002478_02522;MGYG000002171_02941;MGYG000000170_00600 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,4ANVI@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000098_00251 0.2 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 432798 0 0 839948 0 0 0 0 0 0 0 0 0 0 709724 0 511804 0 0 0 0 870037 0 0 0 0 953028 0 0 0 583807 0 0 0 0 0 0 0 454186 0 0 617564 0 0 0 0 0 0 0 0 0 0 619523 0 440990 0 0 0 0 860741 0 0 0 0 672265 0 0 0 502553 0 0 0 0 0 0 0 480013 0 0 627260 0 0 0 0 0 0 0 0 0 0 568068 0 1267148 0 0 0 0 886009 0 0 0 0 849328 0 0 0 127385 0 0 0 0 0 0 0 293804 0 0 133817 0 0 0 0 0 0 0 0 0 0 111975 0 215848 0 0 0 0 246905 0 0 0 0 444649 0 0 0 134235 0 0 0 0 0 0 0 173020 0 0 158690 0 0 0 0 0 0 0 0 0 0 255337 0 409890 0 0 0 0 281924 0 0 0 0 451120 0 0 0 198234 0 0 0 0 0 0 +(Gln->pyro-Glu)QAIVAEVSEVAK MGYG000002514_01948;MGYG000002535_04030;MGYG000002506_03691;MGYG000002323_03991;MGYG000000107_05463;MGYG000003365.1_02175;MGYG000003390_01039;MGYG000003372_03272;MGYG000000235_04432;MGYG000002494_02479;MGYG000002366_04477;MGYG000002500_00410;MGYG000003360_03951;MGYG000002534_04620;MGYG000002515_03652;MGYG000000093_05651;MGYG000002502_01841;MGYG000002507_00341 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,3XM5M@561|Escherichia 0.9444444444444444 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002514_01948 0.05555555555555555 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02864:RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10 1.0 none 1.0 469971 261507 406321 514527 0 734702 462577 458419 559299 916499 0 0 0 516988 452942 303909 290789 0 489071 467385 539556 611467 0 723018 214824 595960 624111 0 591350 731889 0 254483 357766 538733 268928 649385 318867 0 591893 640954 602214 842838 0 1451697 806264 832900 726168 1170190 0 0 0 1033990 824133 670508 953702 0 1314963 687145 942446 1704660 0 1407406 952879 1034591 729706 0 1002097 1043555 0 736998 630167 639672 633013 605806 701633 546204 408244 289517 364646 333959 0 572085 449433 322047 247212 434484 0 0 0 451063 455576 297581 119243 0 372817 376281 372443 485359 0 589230 339975 394911 490648 0 493816 348436 0 0 341130 616387 289368 340046 271030 287741 308096 248837 368682 178197 0 432834 373363 343032 138590 359528 0 0 0 191946 161014 244811 244564 0 242016 236746 179005 587210 0 267591 332821 299313 187732 0 318483 319085 0 275724 392714 514537 382685 419987 150790 114803 0 0 0 0 0 0 0 0 0 107952 0 0 0 0 0 0 0 0 0 91394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAKPGVK MGYG000000196_03583 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,4AKHK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000196_03583 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 0 197584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1892886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 69545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAKPVETK MGYG000003266_01664;MGYG000002050_01168;MGYG000004681_00242;MGYG000001636_01239;MGYG000002961_00289 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CV5V@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 - 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003266_01664 0.2 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 434894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1574352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QALAEEMSNQLR MGYG000004735_00784 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,27JJX@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00784 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1207153 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QALDNITPQVEVK MGYG000002293_00508;MGYG000003697_01471;MGYG000002834_00437;MGYG000002603_01770 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,22WEA@171551|Porphyromonadaceae 0.75 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00508 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1143466 0 0 0 0 0 0 0 1793191 0 0 0 0 0 0 1885459 0 0 0 0 3145356 0 0 0 0 1909933 0 0 0 0 556874 0 0 0 0 1262850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QALELPR MGYG000002477_04285;MGYG000002323_01056;MGYG000002506_04652;MGYG000002515_02505;MGYG000002534_01239;MGYG000002494_00468 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,3VZ7M@53335|Pantoea 0.5 1236|Gammaproteobacteria 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002477_04285 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83087 0 188292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 173544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QALENIKPQIEVR MGYG000000953_00047;MGYG000002485_00024 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0049@1|root,COG0049@2|Bacteria,3790N@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000953_00047 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724184 1564092 0 959815 1299993 0 751768 0 1993197 2046816 978957 2031224 770933 0 2062139 0 0 0 0 0 1495274 0 1352727 0 0 712346 0 0 0 1616360 810661 1763970 0 0 0 0 1308754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QALENITPQVEVK MGYG000001562_01942;MGYG000002203_01144;MGYG000001415_01614;MGYG000004536_01501;MGYG000001655_00055;MGYG000001420_02919;MGYG000000437_02347;MGYG000001546_01214;MGYG000004756_01927;MGYG000001663_00083;MGYG000000074_01965;MGYG000000053_00690;MGYG000000414_01221;MGYG000003279_01342;MGYG000003542_01354;MGYG000004822_02482;MGYG000001302.1_01163;MGYG000004658_00151;MGYG000003908_02195;MGYG000002082_00490;MGYG000002007_02084;MGYG000003952_00896 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,22V8M@171550|Rikenellaceae 0.8636363636363636 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001562_01942 0.045454545454545456 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 349054 0 0 0 0 481778 0 487559 0 525788 0 0 346431 0 0 384922 0 0 528206 509117 554844 274943 0 180702 703776 309621 482118 0 396904 385922 0 0 0 0 0 434496 411169 0 362545 0 0 0 0 168904 0 463032 427935 748255 0 0 247674 0 0 484537 0 0 633918 649505 304422 0 0 301232 390620 453284 0 0 655730 516428 0 0 0 0 0 311790 308176 0 285374 0 0 0 0 289271 0 268432 349379 0 0 0 421814 0 0 197001 0 0 300858 303588 276396 288025 0 0 284929 401462 0 0 277010 321551 0 0 0 0 0 302059 0 0 310455 0 0 609224 0 342888 0 222010 171591 380533 0 0 0 0 0 433972 0 0 191545 259718 0 449277 0 0 0 326152 137740 0 276100 407088 0 0 0 0 0 419486 296615 0 599987 0 0 735202 0 935463 0 671416 797289 654210 0 0 563679 0 0 783377 0 0 1136707 1049969 551694 410203 0 483178 678451 779889 636664 0 667632 977898 0 0 0 0 0 565659 761637 0 +(Gln->pyro-Glu)QALINSLC(Carbamidomethyl)AK MGYG000000233_01229;MGYG000004747_01854;MGYG000000205_02291 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 0.6666666666666666 adh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_01229 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 837404 0 0 0 0 0 0 1282300 881329 1139884 0 0 0 0 0 0 622421 0 827353 915113 0 0 0 0 1083084 790637 0 0 0 0 0 0 0 983890 0 921179 583483 0 1255251 0 0 0 0 0 0 1932072 283849 1866935 0 0 0 0 0 0 863891 0 1173323 1173745 0 0 0 0 1394129 1207309 0 0 0 0 0 0 0 1945711 0 1130231 877949 0 638385 0 0 0 0 0 0 759130 899941 750251 0 0 0 0 0 0 0 0 811566 271402 0 0 0 0 489858 787250 0 0 0 0 0 0 0 1393403 0 639429 629314 0 0 0 0 0 0 0 0 272539 122571 287767 0 0 0 0 0 0 0 0 201674 401520 0 0 0 0 372499 194473 0 0 0 0 0 0 0 394227 0 0 0 0 0 0 0 0 0 0 0 234598 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330306 251651 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QALTAELSNQMK MGYG000002517_02914 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02914 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QALYEAIESR MGYG000001338_03091;MGYG000000200_01731 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 pgcA 1.0 - 1.0 5.4.2.2,5.4.2.8 1.0 ko:K01835,ko:K01840 1.0 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00114,M00549 1.0 R00959,R01057,R01818,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001338_03091 0.5 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). | phosphomannomutase. phosphoglucose mutase. | phosphomannose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. | alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. | alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2]|K01840:manB; phosphomannomutase [EC:5.4.2.8] 1.0 none 1.0 0 95989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 200911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288887 0 0 0 0 0 0 0 0 374813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333339 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAM(Oxidation)QNVHFR MGYG000004271_01550;MGYG000000271_02821 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG4166@1|root,COG4166@2|Bacteria,1VRU1@1239|Firmicutes,255ES@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 ABC transporter, substrate-binding protein, family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01550 0.5 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAMQNVHFR MGYG000004271_01550;MGYG000000271_02821 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG4166@1|root,COG4166@2|Bacteria,1VRU1@1239|Firmicutes,255ES@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 ABC transporter, substrate-binding protein, family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01550 0.5 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 1838608 0 0 0 0 884884 2397506 0 1590497 1204473 0 1154132 0 1854773 1983886 0 0 0 0 1422746 1501664 657890 0 565911 1743416 1562822 1672641 0 0 0 0 0 0 1932915 0 1799406 1723589 0 0 0 0 0 0 303237 0 0 421325 0 0 0 0 0 0 0 0 0 0 235686 0 0 0 0 0 0 569722 0 0 0 0 0 0 0 0 0 0 0 528356 0 0 0 0 246986 566776 0 245479 434036 0 391084 0 262892 342566 0 0 0 0 494184 172405 257150 0 0 709938 338432 478594 0 0 0 0 0 0 624951 0 274104 353686 0 397219 0 0 0 0 0 356317 0 319759 360590 0 663040 0 119072 458542 0 0 0 0 0 604399 205981 0 0 463548 462668 457531 0 0 0 0 0 0 633412 0 490874 316843 0 844884 0 0 0 0 726071 1099997 0 1071391 733675 0 1176113 0 807498 989138 0 0 0 0 1130446 634760 278771 0 736793 918806 838845 808540 0 0 0 0 0 0 1328473 0 846858 1138249 0 +(Gln->pyro-Glu)QAMQNVHFRR MGYG000000271_02821 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG4166@1|root,COG4166@2|Bacteria,1VRU1@1239|Firmicutes,255ES@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 ABC transporter, substrate-binding protein, family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02821 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAMSDAGLKPSDLAK MGYG000002720_01392 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,2N6EU@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 O 1.0 MreB/Mbl protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01392 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAMSVFKDTR MGYG000000184_01405;MGYG000000198_02298;MGYG000001338_00963;MGYG000000142_01694;MGYG000002312_02533;MGYG000004735_01072 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3WHCQ@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 0.8333333333333334 - 1.0 - 1.0 - 1.0 ko:K10546 1.0 ko02010,map02010 1.0 M00216 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.5 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_01405 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10546:chvE; putative multiple sugar transport system substrate-binding protein 1.0 none 1.0 0 539936 0 0 0 0 0 0 0 0 0 364750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 895068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403052 0 0 0 0 0 0 0 0 0 796611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532338 0 0 0 0 0 0 0 0 0 673157 0 0 0 0 0 0 0 0 0 1472640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAN(Deamidated)GAALM(Oxidation)HYGDTTVLSTATASKEPR MGYG000000133_01738;MGYG000001338_01246 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3XZKB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000133_01738 0.5 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609070 0 0 0 0 0 0 +(Gln->pyro-Glu)QANKYKVPR MGYG000004647_01362;MGYG000000450_01762 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,4PQ8I@995019|Sutterellaceae 0.5 28216|Betaproteobacteria 0.5 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000004647_01362 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267799 0 0 0 0 253970 0 0 0 0 274952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408148 0 0 0 0 312290 0 0 0 0 214510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAPLASLEEAVVKGLASDKGLFMPMTIK MGYG000001337_01137 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis|m__MGYG000001337 1.0 COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,2FMPH@200643|Bacteroidia,4AKDS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Threonine synthase 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001337_01137 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAPVQLDLIK MGYG000002171_01457;MGYG000000243_02392 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0738@1|root,COG0738@2|Bacteria,4NEPI@976|Bacteroidetes,2FP0B@200643|Bacteroidia,4ANX8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Transporter, major facilitator family protein 1.0 gluP 1.0 - 1.0 - 1.0 ko:K02429 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 2.A.1.7 1.0 - 1.0 - 1.0 MFS_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_01457 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02429:fucP; MFS transporter, FHS family, L-fucose permease 1.0 none 1.0 0 0 489463 0 287596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532885 0 0 0 0 81232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166233 0 275947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 198480 0 0 0 0 194870 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQAVVVEEALR MGYG000000223_01130 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,36DHW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_01130 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQDAIKAEAER MGYG000000249_01234;MGYG000001310_00255 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3XYW8@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 8.87 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_01234 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 508091 0 0 0 0 0 0 518652 0 0 0 0 0 0 0 0 599818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609569 0 0 0 669583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 465608 0 0 0 200586 0 0 0 0 187771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQDAIKEEAAR MGYG000002042_01031 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-110|s__CAG-110 sp900762935|m__MGYG000002042 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,267MF@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002042_01031 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQDAIKEEATR MGYG000000743_01190;MGYG000000163_01035;MGYG000000733_01113 domain d__Bacteria 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,267MF@186813|unclassified Clostridiales 0.3333333333333333 186801|Clostridia 0.6666666666666666 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 0.6666666666666666 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000743_01190 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQDAIKSEAER MGYG000000271_00181;MGYG000004271_02124 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00181 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQDAIKTEAER MGYG000000150_02990;MGYG000000201_03495;MGYG000000909_00277;MGYG000001687_00923;MGYG000000213_00523;MGYG000000278_03745;MGYG000004785_01641;MGYG000001247_01746;MGYG000000255_00471;MGYG000000136_00722;MGYG000001186_00373;MGYG000000389_00258;MGYG000000002_01239;MGYG000002517_01401;MGYG000000404_00635;MGYG000001315_00796;MGYG000002393_02328;MGYG000000184_03160;MGYG000002492_01612 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,21Y04@1506553|Lachnoclostridium 0.42105263157894735 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 0.9473684210526315 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_02990 0.05263157894736842 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 1544105 2525117 2272163 1086562 2939666 1778677 605153 445034 730120 0 2253234 1461148 2303679 1785583 1420673 2149797 1606821 1446715 1604426 616092 1595037 1764744 509099 778368 1481739 1267436 1014511 553583 0 1531359 944958 2354096 1480303 1527879 745996 1012463 931611 1610082 1395966 3811652 2092373 1553658 2517056 1142512 1374448 1394064 1106319 0 1683249 985551 1634405 1344649 143871 1427483 1102788 1613307 1068357 1322152 1007970 765422 1143532 1291803 1141425 1342502 1233963 2050603 0 1277862 3718265 2430379 2173706 1928440 1497185 1588941 1248975 0 1982015 5380229 6497841 2079138 2568838 1958427 1593785 2439088 1958777 0 2879151 2194173 3983336 1867758 1957201 4236804 1737949 1023587 2344021 2033212 1833719 1712655 1575526 1789711 2329459 1880258 2440022 2080749 0 2632170 2633266 3895581 5490140 2923583 2480626 1825208 2251833 4057308 2914067 3980708 2000836 3027346 2884007 1979556 2110502 3492283 3270132 0 2770159 2800386 2384735 3916760 4148633 3181214 2617627 1028368 3150456 2661906 2238726 1463785 883302 1295576 3597555 3385675 3907800 511158 0 2944905 3344177 3026794 2619312 2653059 3762237 2669968 3383340 2403564 1890032 3797698 4243684 1587937 2150895 3462257 2340331 1780741 2321507 0 1005232 2561936 2214861 2621512 2892533 2126924 2634018 567158 2277880 1661013 2503875 2377655 910036 2829353 729169 2496420 1229678 814282 0 1481581 5578352 4317052 6592254 2837313 2418353 2721921 3005143 3679565 +(Gln->pyro-Glu)QAQDAIKVEAER MGYG000003695_01035;MGYG000004296_02310;MGYG000000146_01613;MGYG000002279_01755;MGYG000002298_01550 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3XYW8@572511|Blautia 0.4 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 0.6 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003695_01035 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 646862 460207 826566 414204 0 914531 0 811580 317335 460402 642357 613479 989748 362069 711683 757128 570629 0 651060 557269 516084 1074029 0 301898 602954 499029 370171 0 476224 0 597727 513496 762462 485230 607795 398128 369998 643351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288213 0 0 0 837227 1061065 731745 424248 0 464034 291276 723049 455691 642665 437567 381584 645065 400597 723050 580296 546905 0 668712 781370 533116 977498 0 371930 838206 777918 804179 0 536405 0 632864 985417 768443 929637 787180 466364 638499 649521 0 744622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390175 318668 0 0 0 0 0 0 1780908 1895878 1792169 2435573 0 1224800 2319347 1597794 1399668 2458603 1987427 1546475 1051481 2526054 2011627 1551106 1507413 0 1659866 403879 2154344 1934206 0 1086943 1492957 1406908 1656850 0 2551684 0 1533964 2153795 2926135 2188772 1251650 1811117 1362359 1236286 +(Gln->pyro-Glu)QAQDAVAEEATR MGYG000004788_00490 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Lactobacillaceae|g__Companilactobacillus|s__Companilactobacillus farciminis|m__MGYG000004788 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli,3F3M1@33958|Lactobacillaceae 1.0 91061|Bacilli 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004788_00490 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 806102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQDSIKNEAER MGYG000000262_02774 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,25UT8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02774 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184799 0 0 0 0 762445 0 0 0 459473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825884 0 220567 0 0 0 0 0 0 0 0 0 0 873078 0 0 0 0 421774 0 0 0 523633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 373310 0 416999 0 0 0 0 0 0 0 0 0 0 503156 0 0 0 0 255637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQEAIANQATR MGYG000002469_01208;MGYG000001292_01082 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CZ96@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002469_01208 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQEAIKAEAER MGYG000000179_02939 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,21Y04@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02939 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 518633 0 0 344827 0 0 0 0 315241 419462 0 0 0 427780 0 0 0 0 0 347615 0 0 0 0 0 360633 0 0 437384 247684 0 0 0 0 0 477169 133920 0 400530 0 0 218261 0 0 0 0 0 210308 0 0 0 150941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 666755 505236 0 0 0 703895 0 0 0 0 0 477875 0 0 0 0 0 401271 460500 0 726840 0 0 0 0 0 0 640541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1090170 0 0 1377297 630337 558783 0 0 1096078 1218555 0 0 0 1035946 0 0 1175234 0 0 1157450 0 692000 0 717389 0 916172 1056565 0 1357547 666311 0 0 0 0 0 786895 1078725 937356 +(Gln->pyro-Glu)QAQEAIKDEAAR MGYG000002720_01476 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,2N6MD@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein S2 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01476 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 308351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQEAIKDEALR MGYG000002926_00692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,2N6MD@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein S2 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_00692 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 657464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQEAVKEEAQR MGYG000001645_00483 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eubacterium_G|s__Eubacterium_G sp900550135|m__MGYG000001645 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,21Y04@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001645_00483 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 909646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQEAVKEQAER MGYG000002485_02450;MGYG000004828_01989;MGYG000004893_01903;MGYG000000953_00545;MGYG000002574_00367 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0052@1|root,COG0052@2|Bacteria,3795U@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_02450 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 996897 0 643932 0 0 472025 0 1231538 1423599 0 994332 637771 0 1040348 558118 0 392839 0 0 851743 0 757223 0 0 569776 0 0 0 0 0 757950 0 0 0 0 617760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQEAVKNAAER MGYG000002947_00285;MGYG000002961_01438;MGYG000004681_00359;MGYG000002775_01738;MGYG000003266_00512;MGYG000001642_01009;MGYG000000188_00078;MGYG000002970_00272 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CU8M@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002947_00285 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQEAVKTEAER MGYG000001319_00659 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,4BXU0@830|Butyrivibrio 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein S2 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001319_00659 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 966099 0 0 0 0 803005 0 0 0 0 920978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQEAVSNQAVR MGYG000003683_00403 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,4CZ96@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00403 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582624 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 574580 0 202895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQEILDNATNDANNIR MGYG000004719_01421;MGYG000000271_00139;MGYG000000389_00412;MGYG000004271_00266;MGYG000002517_01451 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GARP,HrpE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004719_01421 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254060 0 0 0 0 0 0 0 0 0 0 260868 0 193711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572189 0 +(Gln->pyro-Glu)QAQEILDTDHYGLER MGYG000002477_04282;MGYG000002535_03207;MGYG000000235_01944;MGYG000002534_01242;MGYG000002323_01059;MGYG000002494_00471;MGYG000002500_01182;MGYG000002515_02502;MGYG000002506_04655;MGYG000002504_00799;MGYG000003372_00323 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0466@1|root,COG0466@2|Bacteria,1MUV2@1224|Proteobacteria,1RPCB@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 O 1.0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner 1.0 lon 1.0 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004175,GO:0004176,GO:0004252,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009408,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0017171,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.0 3.4.21.53 1.0 ko:K01338 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,AAA_5,ClpB_D2-small,LON_substr_bdg,Lon_C,zf-C4_ClpX 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002477_04282 0.09090909090909091 endopeptidase La. ATP-dependent serine proteinase. ATP hydrolysis is linked with peptide bond hydrolysis.-!-Vanadate inhibits both reactions.-!-A similar enzyme occurs in animal mitochondria.-!-Belongs to peptidase family S16. Hydrolysis of proteins in presence of ATP. 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K01338:lon; ATP-dependent Lon protease [EC:3.4.21.53] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 804300 0 313386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQESIRDEALR MGYG000000022_01263;MGYG000001300_00246;MGYG000002223_00595;MGYG000000039_00227;MGYG000002224_00296;MGYG000002274_00630;MGYG000002651_00048;MGYG000002545_00160;MGYG000000195_01345;MGYG000002641_00104 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01263 0.1 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 938378 0 1271599 1058267 0 963519 616509 666576 852299 0 695677 0 0 1199293 862534 1180012 1200964 2127004 1206286 0 0 858576 1456001 951603 0 960501 883626 1655978 0 675997 767699 819527 1096341 1316190 0 944255 740645 1060057 1510072 0 1961944 1659054 0 1408051 1968715 911116 1915667 0 1506797 0 0 1676649 1646417 917984 1898249 1516865 2344657 0 0 993547 2253781 1330499 0 1665357 1605494 2051696 0 1738333 1528279 1239215 1785867 1492937 0 1493177 1721276 1269933 609690 0 1106472 974273 0 1197763 764508 707719 1024412 0 961200 0 0 748443 743575 871598 643851 2242339 656980 0 0 639747 1926041 761994 0 647114 710090 2733409 0 544149 994621 695167 585903 773584 0 767076 837981 614464 445846 0 1832790 760052 0 1706993 1136127 651725 841609 0 1233359 0 0 799758 943789 728169 528076 1715591 945647 0 0 2190270 2309863 366827 0 1202609 758392 884144 0 1317561 389149 1131057 1563437 1388744 0 896091 1130759 1734573 0 0 468019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1912716 0 0 0 0 2081700 0 0 0 0 2093484 0 0 0 0 604079 0 0 0 0 413571 +(Gln->pyro-Glu)QAQESIRDEATR MGYG000001157_00347;MGYG000003921_00807;MGYG000003937_00035 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001157_00347 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQETKVDETAADTK MGYG000000133_01632 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01632 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 1.0 none 1.0 0 0 0 316871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155620 0 370306 0 0 0 0 0 0 368444 0 0 0 0 290145 0 0 0 0 0 297625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 701548 828864 1564431 1617439 0 668631 1027821 528539 789508 1672299 1271297 1237486 0 1537207 1088395 530472 1229890 0 973585 0 1057717 510067 0 597565 950710 1065764 1010463 0 1130139 0 945875 1182572 2371237 835805 0 0 1049977 1064845 +(Gln->pyro-Glu)QAQQTGVDAK MGYG000002492_01475 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 carboxylase 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01475 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300870 0 0 0 0 160796 0 0 649467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 772524 0 0 0 0 594512 0 0 480595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564313 0 0 0 0 809289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQTGGDKAAK MGYG000002549_03298;MGYG000001337_00591;MGYG000000196_03335;MGYG000001780_02910;MGYG000000243_01434;MGYG000004876_00281 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,2FMWX@200643|Bacteroidia,4AMIJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner 1.0 ychF 1.0 - 1.0 - 1.0 ko:K06942 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 MMR_HSR1,YchF-GTPase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_03298 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06942:ychF; ribosome-binding ATPase 1.0 none 1.0 0 0 316810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353733 0 0 0 0 199708 0 0 150378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181373 0 0 0 0 282158 0 0 92540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252986 0 0 0 0 220207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47736 0 0 0 0 0 0 0 84610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182805 +(Gln->pyro-Glu)QAQVVMHDQAPALIIAHSTVYEPVRK MGYG000002494_02203 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0747@1|root,COG0747@2|Bacteria,1MUZH@1224|Proteobacteria,1RNES@1236|Gammaproteobacteria,3XMYT@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis 1.0 dppA 1.0 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0008150,GO:0009987,GO:0015833,GO:0020037,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042938,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:0097159,GO:1901363 1.0 - 1.0 ko:K02035,ko:K12368 1.0 ko02010,ko02024,ko02030,map02010,map02024,map02030 1.0 M00239,M00324 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 iSSON_1240.SSON_3846 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02203 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing|Bacterial chemotaxis 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K12368:dppA; dipeptide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 500905 0 0 968673 427949 0 0 0 0 0 0 0 0 631107 0 0 0 0 699457 1461895 0 1047598 0 0 0 0 0 0 0 0 414377 0 0 0 0 473622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQYKTEEGR MGYG000000245_00521;MGYG000004271_00924;MGYG000000271_01230 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM oxidoreductase FAD NAD(P)-binding domain protein 1.0 pyrK_1 1.0 - 1.0 1.18.1.2,1.19.1.1 1.0 ko:K00528,ko:K16951 1.0 ko00920,ko01120,map00920,map01120 1.0 - 1.0 R00858,R10146,R10159 1.0 RC00065 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000245_00521 0.3333333333333333 ferredoxin--NADP(+) reductase. | flavodoxin--NADP(+) reductase. FPR. In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe- 2S] ferredoxins, but in other bacteria it can also reduce bacterial 2[4Fe-4S] ferredoxins and flavodoxin.-!-Formerly EC 1.6.7.1 and EC 1.6.99.4. | This activity occurs in some prokaryotes and algae that possess flavodoxin, and provides low-potential electrons for a variety of reactions such as nitrogen fixation, sulfur assimilation and amino acid biosynthesis.-!-In photosynthetic organisms it is involved in the photosynthetic electron transport chain.-!-The enzyme also catalyzes EC 1.18.1.2. H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]. | NADP(+) + reduced [flavodoxin] = 2 H(+) + NADPH + oxidized [flavodoxin]. 1.0 1.0 1.0 1.0 Sulfur metabolism|Microbial metabolism in diverse environments 1.0 K00528:fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]|K16951:asrB; anaerobic sulfite reductase subunit B 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAQYNFVGASEQLESAHR MGYG000002515_02888;MGYG000002494_04167;MGYG000002323_03571 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1538@1|root,COG1538@2|Bacteria,1MWCJ@1224|Proteobacteria,1RQQV@1236|Gammaproteobacteria,3XMC8@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 1.0 M 0.6666666666666666 Outer membrane channel, which is required for the function of several efflux systems such as AcrAB-TolC, AcrEF-TolC, EmrAB-TolC and MacAB-TolC. These systems are involved in export of antibiotics and other toxic compounds from the cell. TolC is also involved in import of colicin E1 into the cells 0.6666666666666666 tolC 1.0 GO:0002790,GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008104,GO:0008150,GO:0009279,GO:0009306,GO:0009987,GO:0010033,GO:0014070,GO:0015031,GO:0015075,GO:0015267,GO:0015288,GO:0015318,GO:0015562,GO:0015688,GO:0015711,GO:0015833,GO:0015850,GO:0015891,GO:0015893,GO:0016020,GO:0016021,GO:0019867,GO:0022803,GO:0022829,GO:0022838,GO:0022857,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032940,GO:0032991,GO:0033036,GO:0034220,GO:0042221,GO:0042493,GO:0042802,GO:0042886,GO:0042930,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0046618,GO:0046903,GO:0047485,GO:0050896,GO:0051179,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098796,GO:1901678,GO:1902495,GO:1990195,GO:1990196,GO:1990281,GO:1990351 1.0 - 1.0 ko:K12340 1.0 ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133 1.0 M00325,M00326,M00339,M00571,M00575,M00646,M00647,M00696,M00697,M00709,M00720,M00821 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01504,ko02000,ko02044 1.0 1.B.17,2.A.6.2 1.0 - 1.0 iAPECO1_1312.APECO1_3378,iEC042_1314.EC042_3326,iECOK1_1307.ECOK1_3463 1.0 OEP,SPOR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_02888 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|Cationic antimicrobial peptide (CAMP) resistance|Two-component system|Bacterial secretion system|Plant-pathogen interaction|Pertussis 1.0 K12340:tolC, bepC, cyaE, raxC, sapF, rsaF, hasF; outer membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 591200 0 0 0 1149384 0 0 0 0 0 0 0 0 0 0 0 0 645778 0 0 1092463 0 1098567 0 0 0 0 746393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QASHLALSASETAQK MGYG000002494_02854 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3WXSN@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 NT 1.0 Homologues of the ligand binding domain of Tar 1.0 tsr 1.0 GO:0001101,GO:0001932,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0006935,GO:0007154,GO:0007165,GO:0007172,GO:0008104,GO:0008150,GO:0009593,GO:0009605,GO:0009719,GO:0009966,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0023051,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031399,GO:0032101,GO:0032110,GO:0032268,GO:0032879,GO:0032991,GO:0033036,GO:0034613,GO:0034622,GO:0038023,GO:0040011,GO:0040012,GO:0042221,GO:0042325,GO:0042330,GO:0042802,GO:0042803,GO:0043113,GO:0043200,GO:0043424,GO:0043549,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0046983,GO:0048583,GO:0048870,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051174,GO:0051179,GO:0051246,GO:0051259,GO:0051260,GO:0051270,GO:0051338,GO:0051606,GO:0051641,GO:0051668,GO:0051674,GO:0051716,GO:0060089,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0070727,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071840,GO:0071944,GO:0072657,GO:0080090,GO:0098561,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902021,GO:2000145 1.0 - 1.0 ko:K03406,ko:K05874,ko:K05875,ko:K05876,ko:K05877 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 4HB_MCP_1,HAMP,MCPsignal,TarH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02854 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03406:mcp; methyl-accepting chemotaxis protein|K05874:tsr; methyl-accepting chemotaxis protein I, serine sensor receptor|K05875:tar; methyl-accepting chemotaxis protein II, aspartate sensor receptor|K05876:trg; methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor|K05877:tap; methyl-accepting chemotaxis protein IV, peptide sensor receptor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 425671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 616047 0 0 906677 0 0 0 774067 0 0 0 484603 0 0 754105 0 564134 0 621249 995100 0 788026 762446 0 0 0 646595 946193 0 0 276099 0 0 467438 0 323135 0 0 435670 0 0 0 0 0 0 0 0 0 0 0 0 0 109387 0 0 0 117670 0 0 0 0 0 0 0 0 0 0 0 415526 0 0 0 0 733186 0 0 0 0 0 199770 0 0 0 1365733 0 0 0 0 0 0 1612623 0 0 0 212314 0 0 140896 1293525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 118659 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QASHLAQSASDTAQHGGK MGYG000002494_03457 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3WWBY@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 T 1.0 Homologues of the ligand binding domain of Tar 1.0 tar 1.0 GO:0001101,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006935,GO:0007154,GO:0007165,GO:0007172,GO:0008150,GO:0009593,GO:0009605,GO:0009719,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010243,GO:0010604,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0023051,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032101,GO:0032268,GO:0032270,GO:0032991,GO:0034622,GO:0038023,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0042802,GO:0042803,GO:0043200,GO:0043424,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046983,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051606,GO:0051716,GO:0060089,GO:0060255,GO:0065003,GO:0065007,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071840,GO:0071944,GO:0080090,GO:0098561,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901873,GO:1901875 1.0 - 1.0 ko:K03406,ko:K05875 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 4HB_MCP_1,HAMP,MCPsignal,TarH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03457 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03406:mcp; methyl-accepting chemotaxis protein|K05875:tar; methyl-accepting chemotaxis protein II, aspartate sensor receptor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1052142 1145210 1682878 0 1163240 2627517 1318959 650412 950195 1510423 0 0 568571 1182752 655253 893438 1616701 0 1396378 0 1943021 2384751 0 1870759 1619561 775233 0 0 0 2053647 0 0 1728757 1058470 0 930177 688819 1143412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QASQPAAKPGEKPAAPR MGYG000002438_01914 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1082@1|root,COG1082@2|Bacteria,4NFQY@976|Bacteroidetes,2FWU9@200643|Bacteroidia,22ZRC@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Xylose isomerase domain protein TIM barrel 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01914 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365755 0 0 0 0 0 0 0 0 212447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278477 0 0 0 0 0 0 0 0 137977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587778 0 0 0 0 0 0 0 0 706987 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QASTFNVPR MGYG000002775_00049;MGYG000002970_01003;MGYG000001718_01539;MGYG000002947_00114;MGYG000002961_01072;MGYG000003266_00425;MGYG000002978_00868;MGYG000002919_00399;MGYG000000802_00739;MGYG000000188_00931;MGYG000004681_00043 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0480@1|root,COG0480@2|Bacteria,2GKB3@201174|Actinobacteria,4CU9M@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000002775_00049 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QATAAAVGVSK MGYG000001345_02855;MGYG000002549_01703;MGYG000000196_02098 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia,4ARQC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_02855 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02110:ATPF0C, atpE; F-type H+-transporting ATPase subunit c 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1344676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1311689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 515428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QATEEDILAIYK MGYG000003683_01043 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CZ71@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 fucO 1.0 - 1.0 1.1.1.77,1.1.99.37,1.2.98.1 1.0 ko:K00048,ko:K17067 1.0 ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200 1.0 - 1.0 R00614,R01781,R02257 1.0 RC00034,RC00087,RC00099,RC00188 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01043 1.0 lactaldehyde reductase. | methanol dehydrogenase (nicotinoprotein). | formaldehyde dismutase. propanediol oxidoreductase. | nicotinoprotein methanol dehydrogenase. Nicotinoprotein methanol dehydrogenases have a tightly bound NADP+/NADPH cofactor that does not dissociate during the catalytic process.-!-Instead, the cofactor is regenerated by a second substrate or electron carrier.-!-While the in vivo electron acceptor is not known, N,N-dimethyl-4- nitrosoaniline (NDMA) can serve this function in vitro.-!-The enzyme has been detected in several Gram-positive methylotrophic bacteria, including Amycolatopsis methanolica, Rhodococcus rhodochrous and Rhodococcus erythropolis.-!-These enzymes are decameric, and possess a 5-fold symmetry.-!-Some of the enzymes can also dismutate formaldehyde to methanol and formate. | Enzyme-bound NADPH formed by oxidation of formaldehyde to formate is oxidized back to NADP(+) by reaction with a second formaldehyde, yielding methanol.-!-The enzyme from Mycobacterium sp. DSM 3803 also catalyzes the reactions of EC 1.1.99.36 and EC 1.1.99.37.-!-Formaldehyde and acetaldehyde can act as donors; formaldehyde, acetaldehyde and propanal can act as acceptors.-!-Formerly EC 1.2.99.4. (1) (R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + H(+) + NADH. (2) (S)-propane-1,2-diol + NAD(+) = (S)-lactaldehyde + H(+) + NADH. | A + methanol = AH2 + formaldehyde. | 2 formaldehyde + H2O = formate + H(+) + methanol. 1.0 1.0 1.0 1.0 Chloroalkane and chloroalkene degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Methane metabolism|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00048:fucO; lactaldehyde reductase [EC:1.1.1.77]|K17067:mdo; formaldehyde dismutase / methanol dehydrogenase [EC:1.2.98.1 1.1.99.37] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QATFEEMIAR MGYG000003883_02162;MGYG000002494_01839;MGYG000002506_02873;MGYG000002515_03108;MGYG000002323_00471;MGYG000003372_02670;MGYG000002366_00531;MGYG000003365.1_03992 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0102@1|root,COG0102@2|Bacteria,1RA11@1224|Proteobacteria,1S280@1236|Gammaproteobacteria,3XP67@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly 1.0 rplM 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02871 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003883_02162 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02871:RP-L13, MRPL13, rplM; large subunit ribosomal protein L13 1.0 none 1.0 188212 0 146506 97992 0 321227 121844 0 93066 0 0 0 0 0 0 0 0 0 0 117416 114478 494527 0 266285 64154 0 0 0 0 0 0 87889 0 216648 0 118693 225575 191568 444166 546590 546975 479441 449966 825409 656497 466543 376216 0 0 0 342643 699983 624204 390085 0 0 0 522626 667440 1089322 0 902914 662706 431215 459917 0 666435 0 0 548402 449450 399402 396072 495390 311864 385185 108738 76581 253857 0 307235 351061 202930 196674 296764 0 0 0 108762 244076 204264 159861 0 0 0 233349 207676 337306 0 463987 223947 98455 108163 0 111610 0 0 194318 115730 125120 131224 248001 0 126223 293516 166961 225576 226335 88342 249791 255241 257254 136923 0 0 0 157263 235809 196470 214686 0 0 0 116441 274479 309803 0 92102 282478 312363 114964 0 119144 0 0 266873 277562 407773 312996 254563 127731 231009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QATKDAGKIAGLDVK MGYG000000200_01023;MGYG000000002_00433;MGYG000000255_01223;MGYG000002720_01392;MGYG000002926_00096;MGYG000002989_00635;MGYG000000245_00866;MGYG000000187_00181;MGYG000000262_01374;MGYG000000271_02474;MGYG000001310_00050;MGYG000001319_00507;MGYG000001315_00535;MGYG000000142_01918;MGYG000004733_01142;MGYG000004740_00081;MGYG000000251_02358;MGYG000000127_03199;MGYG000002279_01669;MGYG000000164_00503;MGYG000000562_02511;MGYG000002972_00261;MGYG000004879_00274;MGYG000000153_02121;MGYG000002517_00989;MGYG000004271_00836;MGYG000002042_00970 domain d__Bacteria 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.3333333333333333 186801|Clostridia 0.9629629629629629 O 1.0 Heat shock 70 kDa protein 0.9259259259259259 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 0.9629629629629629 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000200_01023 0.037037037037037035 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QATKDAGKIAGLDVKR MGYG000000200_01023;MGYG000000002_00433;MGYG000000255_01223;MGYG000002720_01392;MGYG000002926_00096;MGYG000002989_00635;MGYG000000245_00866;MGYG000000187_00181;MGYG000000262_01374;MGYG000000271_02474;MGYG000001310_00050;MGYG000001319_00507;MGYG000001315_00535;MGYG000000142_01918;MGYG000004733_01142;MGYG000004740_00081;MGYG000000251_02358;MGYG000000127_03199;MGYG000002279_01669;MGYG000000164_00503;MGYG000000562_02511;MGYG000002972_00261;MGYG000004879_00274;MGYG000000153_02121;MGYG000002517_00989;MGYG000004271_00836;MGYG000002042_00970 domain d__Bacteria 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.3333333333333333 186801|Clostridia 0.9629629629629629 O 1.0 Heat shock 70 kDa protein 0.9259259259259259 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 0.9629629629629629 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000200_01023 0.037037037037037035 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QATKEAGEIAGLK MGYG000004756_00370;MGYG000000003_01212;MGYG000001302.1_00819;MGYG000001562_02334;MGYG000000170_00600 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,22UA3@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004756_00370 0.2 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QATKEAGQIAGLEVK MGYG000004876_01872;MGYG000001346_01172;MGYG000000196_01218;MGYG000000243_00100;MGYG000002478_02522;MGYG000002171_02941 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,4ANVI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004876_01872 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QATKEAGQIAGLEVKR MGYG000004876_01872;MGYG000001346_01172;MGYG000000196_01218;MGYG000000243_00100;MGYG000002478_02522;MGYG000002171_02941 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,4ANVI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004876_01872 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QATKGEVVSHIASDNVLGGK MGYG000002506_03421 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1172@1|root,COG1172@2|Bacteria,1MX7D@1224|Proteobacteria,1RNTS@1236|Gammaproteobacteria,3XN9E@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Part of the ABC transporter complex RbsABC involved in ribose import. Probably responsible for the translocation of the substrate across the membrane 1.0 rbsC 1.0 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015591,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 1.0 - 1.0 ko:K10440 1.0 ko02010,map02010 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 iAF1260.b3750,iAPECO1_1312.APECO1_2713,iB21_1397.B21_03581,iBWG_1329.BWG_3441,iE2348C_1286.E2348C_4060,iEC042_1314.EC042_4137,iEC55989_1330.EC55989_4225,iECABU_c1320.ECABU_c42350,iECBD_1354.ECBD_4280,iECB_1328.ECB_03636,iECDH10B_1368.ECDH10B_3938,iECDH1ME8569_1439.ECDH1ME8569_3638,iECED1_1282.ECED1_4440,iECH74115_1262.ECH74115_5186,iECIAI1_1343.ECIAI1_3934,iECNA114_1301.ECNA114_3899,iECO103_1326.ECO103_4407,iECO111_1330.ECO111_4584,iECO26_1355.ECO26_4828,iECOK1_1307.ECOK1_4199,iECS88_1305.ECS88_4172,iECSE_1348.ECSE_4040,iECSF_1327.ECSF_3598,iECSP_1301.ECSP_4800,iECUMN_1333.ECUMN_4280,iECs_1301.ECs4692,iEcDH1_1363.EcDH1_4217,iEcE24377_1341.EcE24377A_4266,iEcHS_1320.EcHS_A3966,iEcSMS35_1347.EcSMS35_4118,iEcolC_1368.EcolC_4244,iJO1366.b3750,iJR904.b3750,iLF82_1304.LF82_1817,iNRG857_1313.NRG857_18675,iUMN146_1321.UM146_18940,iUMNK88_1353.UMNK88_4562,iUTI89_1310.UTI89_C4305,iY75_1357.Y75_RS18320,ic_1306.c4678 1.0 BPD_transp_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_03421 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10440:rbsC; ribose transport system permease protein 1.0 none 1.0 0 0 0 0 449713 0 375710 306430 0 564373 0 0 0 412632 0 0 0 0 0 0 0 0 0 0 259421 0 0 0 0 415027 0 0 0 529226 0 0 0 0 0 0 0 0 0 0 0 164446 0 304136 0 0 0 185214 0 0 0 0 0 0 0 0 0 0 241430 0 0 0 0 397362 0 0 0 410241 0 0 0 0 0 0 0 0 657662 0 576300 598872 0 667535 0 0 0 343026 0 0 0 0 0 0 0 0 0 0 781367 0 0 0 0 365406 0 0 0 1116532 0 0 0 0 0 0 0 0 559038 0 653020 772250 0 1060264 0 0 0 715703 0 0 0 0 0 0 0 0 0 0 966720 0 0 0 0 949725 0 0 0 1107542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QATQGLANWVK MGYG000001338_03091;MGYG000000002_03130;MGYG000002312_00094;MGYG000000038_02498;MGYG000000251_02538;MGYG000003937_00291;MGYG000000262_02904;MGYG000000084_01848;MGYG000000249_02227;MGYG000000195_00356;MGYG000002212_01534;MGYG000002772_00865;MGYG000003921_01064;MGYG000000200_01731;MGYG000003291_00397;MGYG000002040_00491;MGYG000000022_00865;MGYG000001315_01504;MGYG000004712_00027;MGYG000000909_02129;MGYG000001619_02390 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia 0.47619047619047616 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 0.47619047619047616 pgcA 1.0 - 1.0 5.4.2.2,5.4.2.8 1.0 ko:K01835,ko:K01840 1.0 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00114,M00549 1.0 R00959,R01057,R01818,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001338_03091 0.047619047619047616 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). | phosphomannomutase. phosphoglucose mutase. | phosphomannose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. | alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. | alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2]|K01840:manB; phosphomannomutase [EC:5.4.2.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458004 0 0 0 0 340222 0 0 0 0 247445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259436 0 0 0 0 433525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342557 0 0 0 0 635275 0 0 0 0 723344 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAVENDVHVMGVSSLAAGHK MGYG000002438_02292 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,22WFX@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02292 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 412501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390360 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 729604 0 622260 0 0 0 0 0 0 +(Gln->pyro-Glu)QAVGARPK MGYG000001300_02313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3WJWZ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Belongs to the thioredoxin family 1.0 trxA 1.0 - 1.0 - 1.0 ko:K03671 1.0 ko04621,ko05418,map04621,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 Thioredoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02313 1.0 - - - - 1.0 1.0 1.0 1.0 NOD-like receptor signaling pathway|Fluid shear stress and atherosclerosis 1.0 K03671:TXN, trxA; thioredoxin 1.0 none 1.0 0 0 0 0 0 121996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304908 0 0 0 0 270094 0 0 0 0 0 0 0 0 0 0 470762 0 226741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342554 0 0 0 0 208422 0 0 0 0 0 0 0 0 0 0 237623 0 273716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 977803 0 0 0 0 923874 0 0 0 0 0 0 0 0 0 0 990970 0 1413654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79991 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 411570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAVKPVEVK MGYG000002492_00606 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00606 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1294768 0 0 0 0 934795 0 0 0 0 1400907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1618550 0 0 0 0 1719412 0 0 0 0 2125924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAVMYALDTEK MGYG000002919_00279;MGYG000002947_01121;MGYG000003122_01785;MGYG000004681_01414;MGYG000003096_01010;MGYG000001718_00608;MGYG000001086_01015;MGYG000004746_01539 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0747@1|root,COG0747@2|Bacteria,2GK4Y@201174|Actinobacteria,4CUGK@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Tat pathway signal sequence domain protein 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002919_00279 0.125 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 479000 0 0 0 0 0 0 0 0 0 0 0 0 0 320227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150890 0 0 0 0 0 0 0 0 237716 0 0 0 0 0 0 0 0 0 0 0 0 0 270331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199302 0 0 0 0 0 0 0 0 708850 0 0 0 0 0 0 0 0 0 0 0 0 0 582427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331083 0 0 0 0 0 0 0 0 432733 0 0 0 0 0 0 0 0 0 0 0 0 0 898834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 752459 0 0 0 0 0 0 0 0 813535 0 0 0 0 0 0 0 0 0 0 0 0 0 355329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 645305 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAVPLLRTEAPIVGTGIEK MGYG000000243_01980;MGYG000004763_01697;MGYG000002478_00806 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0085@1|root,COG0085@2|Bacteria,4NF8D@976|Bacteroidetes,2FMDI@200643|Bacteroidia,4AKI0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01980 0.3333333333333333 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03043:rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAVTNADKTISSIKR MGYG000002276_02250;MGYG000004087_01928;MGYG000003355_02854;MGYG000001698_00974;MGYG000000139_01467;MGYG000004869_03374;MGYG000002989_00635;MGYG000000562_02511;MGYG000000179_03775;MGYG000001689_04245;MGYG000000187_00181;MGYG000000262_01374;MGYG000000287_03181;MGYG000000198_01270;MGYG000003427_02364;MGYG000001652_01558 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.25 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002276_02250 0.0625 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 500399 0 340731 0 0 0 0 170701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228570 0 0 0 195342 0 0 0 0 145161 0 441231 0 0 0 0 0 0 447355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 972457 0 0 0 0 0 0 0 0 0 0 1160711 0 720825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 557698 1174007 1499914 0 0 0 0 1127044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1307813 0 0 0 1121294 0 0 0 0 886596 +(Gln->pyro-Glu)QAVTNADRTISSIKR MGYG000000142_01918;MGYG000004733_01142;MGYG000000255_01223 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01918 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAVTNAEKTISSIKR MGYG000004740_00081;MGYG000000153_02121;MGYG000000245_00866;MGYG000002517_00989;MGYG000000271_02474;MGYG000001315_00535;MGYG000004271_00836;MGYG000000002_00433;MGYG000000164_00503 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 0.5555555555555556 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004740_00081 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAVTNPQNTLFAIKR MGYG000002494_02915;MGYG000002323_00619;MGYG000002506_04145;MGYG000002515_00010 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,1RMDD@1236|Gammaproteobacteria,3XM30@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02915 0.25 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 1440029 0 0 0 0 625780 0 1168026 960628 1348531 1191538 1636117 0 478309 0 0 0 0 927392 0 0 906450 0 0 0 980340 1283124 0 0 0 0 688301 0 925646 1274203 663027 0 0 1647228 0 0 0 0 2225953 2212880 1434306 1894529 1424170 552261 1628038 0 2660865 0 0 0 0 3712746 0 0 0 0 2305667 0 711813 1889925 0 0 0 1634560 1957725 0 1687655 1408964 1937061 1695653 0 906474 0 0 0 0 871691 911192 839631 498670 1262238 0 812584 0 492631 0 0 0 0 0 0 0 1078122 0 753077 0 1173257 656403 0 0 0 557799 901456 0 771709 0 801113 567406 0 619809 0 0 0 0 331116 0 482166 591833 0 948333 0 0 688248 0 0 0 0 0 0 0 587177 0 0 0 401792 728436 0 0 0 447133 477060 0 667568 0 684739 575162 0 0 0 0 0 0 523166 375536 1282458 0 697841 496261 0 0 0 0 0 0 0 349270 0 0 450092 0 609035 0 0 598198 0 0 0 0 0 0 804928 526961 508436 0 0 +(Gln->pyro-Glu)QAVTNVDR MGYG000002943_00903;MGYG000001292_00143;MGYG000001283_01100;MGYG000001443_05092;MGYG000003452_00557;MGYG000000111_01884;MGYG000003683_01758;MGYG000000756_01483 class d__Bacteria|p__Actinobacteriota|c__Actinomycetia 1.0 COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,4CZDX@85004|Bifidobacteriales 0.625 201174|Actinobacteria 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679 0.75 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl,TIR_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002943_00903 0.125 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 689711 0 0 0 0 396615 0 0 0 0 613969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAYALNINYSATQRQ MGYG000000243_02199;MGYG000002171_02038 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0848@1|root,COG0848@2|Bacteria,4NKT1@976|Bacteroidetes,2FM42@200643|Bacteroidia,4APFS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 COG NOG14448 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K03559 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 ExbD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02199 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03559:exbD; biopolymer transport protein ExbD 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461910 0 0 0 0 410076 0 0 286152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 373239 0 0 0 0 258272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAYDC(Carbamidomethyl)LTHGLTTVC(Carbamidomethyl)EIGR MGYG000001636_00244;MGYG000002050_00004;MGYG000003266_01688;MGYG000002065_00521;MGYG000001642_00469 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4CXAV@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 Q 1.0 Amidohydrolase family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001636_00244 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 823344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QAYILQNEDKR MGYG000002494_02083 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RMGP@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family 1.0 glpD 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004368,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0006072,GO:0006091,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009331,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016614,GO:0016901,GO:0019637,GO:0022900,GO:0031224,GO:0031226,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046168,GO:0046434,GO:0048037,GO:0050660,GO:0050662,GO:0052590,GO:0052646,GO:0055114,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:1901135,GO:1901136,GO:1901265,GO:1901363,GO:1901575,GO:1902494,GO:1990204 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iSSON_1240.SSON_3663 1.0 DAO,DAO_C 1.0 - 1.0 - 1.0 - 1.0 GH36 1.0 MGYG000002494_02083 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156766 0 0 0 0 0 0 0 0 0 0 0 0 552854 0 0 0 0 0 0 0 0 498979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 617725 566304 0 0 0 0 0 0 0 0 0 541723 0 0 0 0 0 0 0 0 0 0 754295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 451651 816719 0 0 0 0 0 0 0 0 0 0 0 498363 0 0 0 0 0 0 0 0 150019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174051 636281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QC(Carbamidomethyl)EAEETTK MGYG000000997_00886;MGYG000000245_00417;MGYG000000164_00893;MGYG000002517_01841;MGYG000004271_02055;MGYG000000271_00295 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_00886 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04078:groES, HSPE1; chaperonin GroES 1.0 none 1.0 0 0 0 0 0 344621 976216 687317 613187 753054 0 518118 441939 544578 355326 338251 287487 0 623427 531642 0 459436 0 321688 633361 644393 658211 0 0 847442 0 0 0 538094 0 831635 629537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754458 0 0 996023 0 0 352108 975947 703870 492950 448144 372973 309730 795030 953652 366593 611535 0 300413 600074 0 0 0 0 1338604 1171139 1302628 0 0 656457 0 422270 377304 960205 1023134 1191079 946451 0 664781 0 598640 0 0 900958 162216 501310 727256 850972 959971 598429 1334528 742780 1111936 949106 1005901 0 860566 744458 0 534694 0 713961 928226 1050735 862014 0 0 868636 0 347652 740926 850973 917274 808456 1528423 896689 +(Gln->pyro-Glu)QC(Carbamidomethyl)KGEGETAK MGYG000000013_01972;MGYG000002478_01954;MGYG000001378_04028;MGYG000002935_01218;MGYG000001750_00043;MGYG000004763_02063;MGYG000001346_03576;MGYG000000243_02666;MGYG000001783_00760;MGYG000002549_04091;MGYG000001835_00524;MGYG000001345_03177;MGYG000004479_00322 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0233@1|root,COG0233@2|Bacteria,4NF95@976|Bacteroidetes,2FPZE@200643|Bacteroidia,4AKS9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another 1.0 frr 1.0 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02838 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 RRF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_01972 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02838:frr, MRRF, RRF; ribosome recycling factor 1.0 none 1.0 505236 0 679150 611673 635822 495162 519358 505250 0 468780 832317 405882 0 0 0 0 0 0 0 426791 678793 644728 0 602477 656040 600151 592907 0 0 0 0 344026 832628 0 0 0 537800 842781 406515 0 533511 590385 608253 537719 394155 659627 0 465560 1067577 785436 0 0 0 0 0 0 0 395047 281640 526547 0 405864 490336 582368 542411 0 0 0 0 567986 315748 0 0 0 393170 465277 104197 0 277844 126428 281178 274911 65839 79636 0 151088 289988 184578 0 0 0 0 0 0 0 305968 71860 181362 0 341130 221153 101121 331441 0 0 0 0 274916 209431 0 0 0 209511 189198 207208 0 211893 263186 164786 0 295969 201757 0 109275 179246 194184 0 0 0 0 0 0 0 190748 0 126846 0 0 256558 347363 270960 0 0 0 0 107681 0 0 0 0 216596 104990 104481 0 139405 214151 249551 193771 198552 0 0 171972 279286 255568 0 0 0 0 0 0 0 210429 0 225278 0 215798 0 190744 66127 0 0 0 0 0 116286 0 0 0 298393 223348 +(Gln->pyro-Glu)QC(Carbamidomethyl)SIGVTAR MGYG000000003_01141;MGYG000001302.1_00873;MGYG000003952_01072 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG2066@1|root,COG2066@2|Bacteria,4NERJ@976|Bacteroidetes,2FM3D@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the glutaminase family 1.0 glsA 1.0 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.0 3.5.1.2 1.0 ko:K01425 1.0 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 1.0 - 1.0 R00256,R01579 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glutaminase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_01141 0.3333333333333333 glutaminase. L-glutamine amidohydrolase. - H2O + L-glutamine = L-glutamate + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Glutamatergic synapse|GABAergic synapse|Proximal tubule bicarbonate reclamation|MicroRNAs in cancer|Central carbon metabolism in cancer 1.0 K01425:glsA, GLS; glutaminase [EC:3.5.1.2] 1.0 none 1.0 0 0 0 1083684 0 0 948483 0 915118 0 0 0 0 1092737 0 0 0 0 0 0 1518069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1295586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QC(Carbamidomethyl)SLGVTAR MGYG000000003_01141;MGYG000002007_00949 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG2066@1|root,COG2066@2|Bacteria,4NERJ@976|Bacteroidetes,2FM3D@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the glutaminase family 1.0 glsA 1.0 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.0 3.5.1.2 1.0 ko:K01425 1.0 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 1.0 - 1.0 R00256,R01579 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glutaminase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_01141 0.5 glutaminase. L-glutamine amidohydrolase. - H2O + L-glutamine = L-glutamate + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Glutamatergic synapse|GABAergic synapse|Proximal tubule bicarbonate reclamation|MicroRNAs in cancer|Central carbon metabolism in cancer 1.0 K01425:glsA, GLS; glutaminase [EC:3.5.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1376910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDAADAATAVEGGM(Oxidation)YQALK MGYG000002438_00802 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,22WD0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00802 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 803186 0 0 0 0 0 0 0 0 847936 0 0 0 0 0 0 0 0 649901 0 401045 0 0 0 0 0 0 0 699917 0 0 0 0 0 0 0 0 0 667975 0 0 0 0 0 0 0 0 669222 0 0 0 0 0 0 0 0 441629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 574707 0 0 1557911 528128 0 0 0 0 0 1735594 1320535 0 0 0 0 1096815 0 0 2740355 490897 993276 1064791 0 0 0 778403 0 2669444 0 1681885 0 0 0 0 0 0 +(Gln->pyro-Glu)QDAAPAQTEQTTEAAVVEEGGGLHK MGYG000002478_02040;MGYG000004797_01477 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02040 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 10123621 8347296 6771949 15163203 9366193 0 15632073 6462576 12671670 9593421 0 10367084 9985033 8901924 9421787 12308752 9893782 8593017 9349244 9362224 0 9385307 14405064 0 11620533 12331470 12242496 12763877 12843494 0 13184713 10749866 8120197 4624403 0 14892570 9575807 7198368 10440364 6024302 8689673 13105201 12117196 11750321 9475108 13764364 10385627 10357881 17098365 9861428 18399624 13276632 13571209 20616360 9665170 7942920 12635638 9607932 11316892 10305498 8068655 8123936 10791422 12390135 11691975 6752119 10671397 11062699 8355615 10803966 9668049 6751782 0 8609047 10571625 8619471 6507082 4715417 6468598 5926459 8779407 6991292 9024762 5095902 9694021 5819302 6438836 7899775 8027918 6098856 5509149 7406913 5654420 11291755 6251765 5275005 5754398 5103355 8818630 6130804 5795171 7376385 5742143 11514493 6886158 5317933 9241207 3819772 4452939 3421210 0 7488233 7646597 5560098 2388711 1430016 1715728 865677 1599229 1618759 1855478 2032565 1751477 2021630 1470982 1845218 2414682 2018692 1786966 352034 1854563 1008901 2182536 2022154 2332851 1555202 309466 1359159 318545 1762938 1834838 763156 1989962 0 238959 1682477 1682646 942328 0 2863149 2111930 1900241 13048597 8857772 6889471 9066833 21713466 11770632 12237733 13661363 13389845 4787464 9832735 8146071 20410932 9569924 10794707 19439544 10474894 0 12925215 15186052 7359048 10150286 0 11791927 13190434 15346805 12491069 0 13197649 12645921 8908169 12036027 7842275 11871374 0 12197516 13822834 10525067 +(Gln->pyro-Glu)QDAAPAQTEQTTEAAVVEEGGGLHKELK MGYG000002478_02040;MGYG000004797_01477 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02040 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 6062212 6500718 14899316 7290078 14106018 6906359 6423798 7646234 7165461 7206946 7810877 7218170 13885093 9182894 4471225 9611928 8450363 5348013 7661160 5852852 5037943 6770523 4578887 7603212 6327900 8548069 5897192 7273271 426695 8980544 16129467 1004981 11272635 2873264 0 5183343 8331770 9895077 1148938 1001548 1076345 1296682 3721538 1437235 1081399 1269367 914893 1703869 2621523 882753 4335133 1338918 2192502 2131964 1636073 0 899620 1010964 1179711 1769995 0 1137464 1424694 1114635 1601475 0 2197456 1275991 1272721 3519491 1558781 775881 0 1245527 1258088 1409033 3033306 3650292 4604448 5355271 5227142 5183453 2589685 3455718 3237350 4234332 3663016 4241942 6209467 2684314 2198452 4541014 3352291 3733128 2444564 2605536 2217087 2400300 2902940 3633417 2798974 3615889 2279237 2338131 3806083 2802374 3971784 3716302 3200619 1840269 0 3076764 4154706 2892807 997274 473886 1191879 1203745 741545 1154633 756671 1356103 1011819 1417862 669304 941477 1346251 816212 1458666 879473 557077 836462 1668088 791467 1122100 1015906 653330 736864 1065180 1171223 1239580 829517 790095 1056484 713004 806352 984216 720852 0 1034307 561715 883463 2540697 2633440 3670973 6993780 8533535 6112452 2225135 2202673 4194312 2642472 4954862 3635050 15199088 2952972 2368358 4846027 3906617 965275 3822522 2743914 1292188 3665413 898646 4407882 2700417 3725924 3187377 1087617 5047419 3123676 5484449 5647460 4475667 2143643 0 3782140 9928250 5927193 +(Gln->pyro-Glu)QDAKPEEGFVFTTVK MGYG000000196_04371 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia,4AKZY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase C1-like family 1.0 pepC 1.0 - 1.0 3.4.22.40 1.0 ko:K01372 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_C1,Peptidase_C1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04371 1.0 bleomycin hydrolase. aminopeptidase C (Lactococcus lactis). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain.-!-Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity.-!-Known from bacteria as well as eukaryotic organisms.-!-Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates.-!-Belongs to peptidase family C1. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. 1.0 1.0 1.0 1.0 - 1.0 K01372:BLMH, pepC; bleomycin hydrolase [EC:3.4.22.40] 1.0 none 1.0 0 0 0 0 0 0 1030814 0 0 979509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1338888 0 0 0 0 0 0 0 0 1646690 0 0 1404440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1340167 0 0 0 0 0 0 0 0 995436 0 0 495997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 865611 0 0 0 0 0 0 0 0 664738 0 0 561793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545764 0 0 0 0 0 0 0 0 586372 0 0 392082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239284 0 0 +(Gln->pyro-Glu)QDAPAAEQTEQAAPAAQAAPADEAAAPVVAEEGGIHK MGYG000003681_00101 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_00101 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3504456 1284812 2423272 5021798 2463381 0 3972434 5654383 3876042 5039955 0 0 0 5798455 5904859 0 3553773 0 4931262 4837046 4639455 0 0 0 5646424 5588508 5381936 0 3477748 5404629 2649729 2915321 2438423 3737211 4752946 3457610 4013178 3199467 841856 422189 792690 1047905 1024683 0 1416484 727938 1201369 948026 0 0 0 1051652 869658 0 1071442 0 926684 689745 125651 0 0 0 153722 1179370 819002 0 1151046 265375 999761 491261 228919 653107 866857 1074747 1038843 379274 740636 650156 728034 295492 862873 0 1147024 275356 1141359 291332 0 0 0 568330 859698 0 869360 0 1238291 1018480 1051537 0 0 0 630997 906677 346219 0 1065783 1042511 432015 664562 748566 1400147 956097 997854 393022 1025541 0 0 0 0 0 0 403975 372859 296150 0 0 0 0 0 171485 0 375013 0 0 0 274377 0 0 0 146430 546740 200040 0 0 522784 0 0 0 320297 699987 284572 469272 0 +(Gln->pyro-Glu)QDAPAAEQTEQAAPAAQAAPADEAAAPVVAEEGGIHKEIK MGYG000003681_00101 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_00101 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1017326 0 0 0 711440 1125609 0 0 0 0 0 0 0 0 0 0 0 672188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 548085 0 0 0 289832 263601 0 0 0 0 0 0 0 0 0 0 0 543983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 569582 0 0 0 316395 649429 0 0 0 0 0 0 0 0 0 0 0 495601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDAPAAEQTEQAAPAAQAAPADEVAAPAVEAEEGGIHK MGYG000001313_03230 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_03230 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1788708 0 1335192 0 0 1830438 2332456 1251059 2131685 1758477 0 0 1091194 0 1654763 0 2001773 5027607 1224988 0 0 1163159 4273103 2031025 0 2287082 1347070 3274839 1858824 0 2224170 1155392 1243366 1673642 1654922 2274336 2001489 1630122 336193 0 495492 0 0 452820 515071 293752 261748 405113 0 0 610933 0 455631 0 298883 0 426211 0 0 519978 0 0 0 492464 522412 0 191765 0 297496 340107 172232 220931 369075 495031 466863 443095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDAPAAEQTEQAAPAAQAAPADEVAAPAVEAEEGGIHKEIK MGYG000001313_03230 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_03230 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1008709 0 1647525 0 0 1728740 0 1370070 1210871 1265912 0 0 1121537 0 0 0 1491881 2156816 0 0 0 1047257 1365547 1422156 0 1531904 0 1838381 0 0 1594571 1126946 912216 0 0 1194974 1016189 1167213 293786 0 239398 0 0 346516 0 183102 243279 304285 0 0 298360 0 0 0 129216 0 0 0 0 268474 0 0 0 298179 0 0 0 0 0 171198 216125 0 0 318460 174190 335960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDAPAAEQTEQAAPAAQAAPAGDATVEAEEGGIHK MGYG000001780_00327;MGYG000002455_01561 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001780_00327 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 882037 0 0 1289853 0 466264 1138252 0 0 0 0 0 753720 0 826779 0 0 546666 0 0 0 757105 782573 1081858 807984 984992 977075 570211 1108400 0 902565 0 0 1441133 749467 0 787685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 434278 0 0 602308 0 0 715864 0 0 0 0 0 581989 0 618306 0 0 380783 0 0 0 321458 638452 292651 0 475736 461498 0 637234 0 275455 0 0 473994 531883 0 623801 0 1674966 0 0 1023348 0 1447952 2310946 0 0 0 0 0 2527465 0 1581100 0 0 9251856 0 0 0 1160269 6862909 1587107 2682415 2967624 2386554 6781342 1105035 0 1004045 0 0 3542924 2662103 0 2253015 0 +(Gln->pyro-Glu)QDAPAAEQTEQAAPAAQAAPAGDATVEAEEGGIHKEIK MGYG000001780_00327;MGYG000002455_01561 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001780_00327 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 819499 0 962809 800753 986862 0 433760 1144448 0 0 0 1155846 526051 0 0 0 0 200863 874890 0 0 0 554659 0 0 734581 0 493127 0 0 0 0 822171 1080038 0 0 386420 710863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1312576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280094 0 578368 557259 538870 0 336728 907170 0 0 0 354757 319245 0 0 0 0 536904 945136 0 0 0 0 0 0 602275 0 609345 0 0 0 0 493948 542296 0 0 359404 507173 578042 0 798759 1354902 890041 0 798282 587618 0 0 0 691867 2180407 0 0 0 0 647375 837155 0 0 0 854007 0 0 1085606 0 809878 0 0 0 0 859860 1436213 0 0 1749459 1051534 +(Gln->pyro-Glu)QDAPAAEQTEQAAVAPAADAAAPAAMEAAEGGIHK MGYG000001346_00886 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_00886 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 439339 0 0 0 0 0 464929 449339 314864 467433 1211713 635403 0 478702 349375 250424 388662 0 0 344860 444638 0 558335 454829 0 452361 386320 396630 0 0 457930 317848 0 416866 322672 451916 419781 0 1378080 0 1192805 0 1282303 1557530 1515931 1952846 1205982 2249794 2163723 4557516 0 1982588 2064573 293258 1630941 592320 0 1723983 2120572 1906300 353189 544061 0 2076745 1787536 413443 0 0 1088762 1574798 1365921 1368279 1358984 1221316 1221981 1011653 1330048 0 1385918 0 1796408 1164072 2018422 1427390 1618554 1313569 2804495 1912155 0 1266174 1414997 1565605 1521213 3291157 0 1215227 1677316 1151188 2756962 1440155 0 1636930 1307708 2108435 0 0 1536936 988773 1259301 629733 1346858 1701062 1207108 1196988 1014037 0 353812 0 1012037 777872 858005 843925 976055 955945 1373488 1414816 0 749952 672064 861043 878995 739307 0 864266 1198276 730082 799876 782045 0 1015472 852554 440364 0 0 925189 866394 452964 934565 818404 1093912 968745 735865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDAPAAEQTEQAAVAPAADAAAPAAMEAAEGGIHKELK MGYG000001346_00886 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_00886 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 367898 0 230233 0 231647 0 0 0 1061151 0 0 0 0 0 0 0 0 0 0 0 269650 0 0 0 0 389275 0 0 0 0 362593 0 0 0 0 269458 0 0 307878 0 404732 0 332792 0 0 0 503990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308279 0 0 0 0 287162 0 0 1337419 0 1141263 0 880627 0 0 0 2250306 0 0 0 0 0 0 1403088 0 0 0 0 934138 0 0 0 0 1110423 0 0 0 0 925310 0 0 0 0 1001022 0 0 947095 0 691800 0 497187 0 0 0 1042138 0 0 0 0 0 0 329097 0 0 0 0 643148 0 0 0 0 825824 0 0 0 0 292181 0 0 0 0 413395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDAPAAEQTEQQAAPAAAQAAPAAAPAAEEGGIHK MGYG000000196_02323 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_02323 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 2267495 2077508 1453130 3358649 1409453 1565911 3442746 2119417 2695982 2457170 1156397 2343770 1272922 1743083 2598854 1519463 2195424 0 1939769 1966381 2379850 1687419 0 2681566 2183376 2784240 3220315 0 3627373 3447074 2732326 2202277 1417087 2892297 2093402 3246255 2468397 1286016 1048779 792181 1026604 1592000 1019325 1053038 1107615 1269853 1070692 1550729 1130132 1071384 240622 1368286 1234447 1114979 1188580 0 1310823 1460246 1302553 1236850 0 1079673 149716 1425999 1273046 0 1347927 1374766 869643 1284979 961999 1102141 931115 1049711 1251664 694370 1190390 942919 1022173 1603508 1561960 1111750 1963579 867142 1506419 765424 981722 1364682 809801 1285617 1093868 980440 1178672 0 938998 938531 1366382 789054 0 1189081 1024837 1656604 1147727 0 1101699 1207887 1072731 884920 887872 1119306 1084774 1647111 1288770 1185906 559590 603890 657405 497860 635560 339653 804292 461523 435098 281885 468607 491940 792415 375810 790949 507966 663374 0 386904 213326 841973 414098 0 490978 347722 448017 211358 0 351178 670337 191655 284031 358632 988103 628276 436723 402030 379187 1319411 1067565 1086829 1162138 1066763 1184714 1785879 2364152 1709664 1094867 850876 1120668 1478552 1529406 1187581 1089116 1117043 0 946423 1814756 1126467 1121907 0 1414348 2405270 2206337 2024824 0 1036182 1826456 844637 1128374 913853 2201223 2568864 1697906 1903585 1023872 +(Gln->pyro-Glu)QDAPAAEQTEQQAAPAAAQAAPAAAPAAEEGGIHKEIK MGYG000000196_02323 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_02323 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 1653798 2285092 2096313 1896402 1731471 1877681 1645880 1836239 1673882 1822520 1114882 1625507 1380017 1861101 1768751 1898594 2640635 0 1481499 1628082 1484034 1421597 0 1817726 1255930 1604995 1518638 0 1964100 1890642 2424390 2832291 1963636 1787105 1705925 1671972 1600227 1431129 203127 132845 129110 117558 384441 446878 267069 80451 116543 306504 202194 252565 248488 184992 492325 256345 380134 0 369292 91142 389851 291894 0 264402 271044 207639 297147 0 216795 259006 463457 583720 265470 432706 139835 227391 114464 250326 666560 948721 1432968 1328321 1497242 1105249 1052790 1240828 1449193 742297 722111 1193680 689026 900082 972562 756780 816718 0 767896 891004 958062 589956 0 1231359 1012414 881312 1263244 0 1167959 1435346 1254346 902177 691080 1078684 1326792 903013 1210032 966800 168875 350126 490962 486306 382578 446285 181310 507542 673514 275263 561450 373124 242275 752834 880305 459028 431023 0 458064 390957 606684 391970 0 630356 1014961 671594 1041854 0 418289 476508 461090 599707 285788 1548419 499734 325913 868161 453951 326201 261961 506971 1712371 691690 657057 475408 501425 1782448 1223611 1217990 739622 1965413 527798 689295 392455 512139 0 0 357988 456550 373732 0 578864 803649 1196957 496721 0 762212 532869 940839 868642 279728 1474136 975715 952871 2155583 1410713 +(Gln->pyro-Glu)QDAPAAEQTEQQAAPAAEATTAAAPAAEEGGIHK MGYG000001345_03404;MGYG000002549_04269 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_03404 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 2742856 0 1459660 3763870 1560595 2124345 4781579 3028357 4072717 3187950 5279588 2961604 1304899 2667245 3480487 1919472 2188247 0 2737626 0 0 2213637 0 4211161 0 3445951 3500402 0 0 3897900 2641307 0 1300969 0 2824593 3949308 2773939 1096234 3197410 0 2335048 3496740 1981219 2201686 2709656 3539896 3031267 3779975 7912781 4022419 265075 3809023 4210377 2587815 3060880 0 3414336 0 0 2093061 0 2205448 0 4104772 3605561 0 0 3763368 1598711 0 1767718 0 2669050 2589234 3268953 2779210 1316728 0 1962003 1269003 2111107 1231329 1841324 1013159 1478725 1294787 3003614 1507716 1294332 1125490 1267782 1418247 1151886 0 931382 0 0 895156 0 1335314 0 1615470 1073364 0 0 1152117 1484725 0 1634429 0 1142943 1550938 1156642 1851819 510113 0 1205028 1231325 1321108 1200276 1544297 1371413 1204295 1412560 2532274 1356266 1789647 1241712 1225653 1348531 429425 0 617031 0 0 944829 0 1310708 0 1267174 1333127 0 0 1581986 656273 0 348570 0 1460328 541834 1485138 1398188 1660048 0 1298460 1521338 2644653 4734187 1922840 1746411 2604440 1541182 3437668 1659961 2555897 2138818 1836310 2498947 2596653 0 1534794 0 0 4613623 0 5363546 0 3536200 2715411 0 0 2606367 1549965 0 1498802 0 2462568 2248160 2719925 1914712 +(Gln->pyro-Glu)QDAPAAEQTEQQAAPAAEATTAAAPAAEEGGIHKEIK MGYG000001345_03404;MGYG000002549_04269 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_03404 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 2158701 0 2557474 0 3034431 1917760 0 3722411 2511598 3446779 6356493 2957230 2113434 0 2009739 0 0 0 2352356 0 0 1703141 0 2762718 0 3222565 0 0 0 3229014 3150435 0 1971663 0 2691766 0 2461833 1540556 913058 0 639788 0 835037 371291 0 666378 779870 881725 2541572 539673 876222 0 1403428 0 0 0 498522 0 0 756293 0 545172 0 840732 0 0 0 810545 490420 0 680189 0 773656 0 878646 912078 767259 0 1881636 0 1677665 1080568 0 704325 1282691 805054 1749947 736041 877142 0 526444 0 0 0 478264 0 0 612009 0 1016459 0 820910 0 0 0 718168 1123750 0 1150318 0 222647 0 865524 1444174 1117136 0 1286045 0 1191913 1344253 0 1542472 1145346 1543244 1780273 1334724 1519857 0 1331967 0 0 0 1155933 0 0 1553011 0 875446 0 1262673 0 0 0 1159888 1125833 0 1487958 0 1318633 0 1329845 1019812 751227 0 904875 0 1580094 2942569 0 548171 939403 1108457 4402280 1005608 2817086 0 552392 0 0 0 500449 0 0 3103765 0 3866916 0 1327604 0 0 0 1380716 1500989 0 1156029 0 1657126 0 3469709 1659887 +(Gln->pyro-Glu)QDAPAAEQTEQQAAPAAEATTATAPAAEEGGIHK MGYG000001378_04234 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_04234 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336309 0 0 0 0 0 0 0 415256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288006 0 0 0 0 510594 0 0 331525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255533 0 0 0 0 471346 0 0 415719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 590905 0 0 0 0 303532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDAPAAEQTEQQAVAPAAEATTAAAPAAEEGGIHK MGYG000000029_00498 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides finegoldii|m__MGYG000000029 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000029_00498 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262677 0 0 290606 0 0 0 0 0 0 0 388771 0 358824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304234 0 0 0 0 432551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 844813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1409208 0 0 0 0 1502833 0 0 748663 0 566555 838347 0 0 0 0 0 0 0 297112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDAPAAEQTEQQAVAPAAEATTAAAPAAEEGGIHKEIK MGYG000000029_00498 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides finegoldii|m__MGYG000000029 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000029_00498 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDAPKEEGFVFTTVK MGYG000000224_01762 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp003545565|m__MGYG000000224 1.0 COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia,4AKZY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase C1-like family 1.0 pepC 1.0 - 1.0 3.4.22.40 1.0 ko:K01372 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_C1,Peptidase_C1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000224_01762 1.0 bleomycin hydrolase. aminopeptidase C (Lactococcus lactis). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain.-!-Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity.-!-Known from bacteria as well as eukaryotic organisms.-!-Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates.-!-Belongs to peptidase family C1. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. 1.0 1.0 1.0 1.0 - 1.0 K01372:BLMH, pepC; bleomycin hydrolase [EC:3.4.22.40] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1338056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDAQKEEPKEEGFVFTTVK MGYG000002478_02236;MGYG000004797_02345 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia,4AKZY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase C1-like family 1.0 pepC 1.0 - 1.0 3.4.22.40 1.0 ko:K01372 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_C1,Peptidase_C1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02236 0.5 bleomycin hydrolase. aminopeptidase C (Lactococcus lactis). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain.-!-Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity.-!-Known from bacteria as well as eukaryotic organisms.-!-Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates.-!-Belongs to peptidase family C1. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. 1.0 1.0 1.0 1.0 - 1.0 K01372:BLMH, pepC; bleomycin hydrolase [EC:3.4.22.40] 1.0 none 1.0 1983439 2022962 2461290 3182027 3707463 2912808 3462525 1588763 3416815 3007397 2786535 2228726 3624584 2700639 2018687 4385041 3745925 1804582 3208330 2723385 2662446 2303332 3218160 3004700 2333186 3035030 2829046 2408189 1832892 3083518 3319591 3276321 2478047 0 2472308 3008141 2256046 2061434 1497677 1374752 1580745 2055598 2351969 1858367 1715119 2364597 2109223 1328107 2145402 1784906 1936618 2075589 1329605 2218014 1318429 1142526 1960205 1765247 1781865 1702595 1304197 927043 1302082 1987963 1982276 1442689 1989796 1483692 876079 2401340 1771540 0 1774092 1765303 1731243 1234371 1023414 937751 1478773 1080560 2307302 1770110 1706462 880325 1916722 1632707 1747328 1797925 1956680 1473079 1324672 1331259 929052 2294797 1458503 1359432 963639 903669 1881520 1494009 911851 1270799 1150895 1845441 969527 1144654 2320177 884243 1281304 0 1217103 1750157 1514704 1079728 374973 333381 363790 448084 461193 556865 278548 424276 376103 679276 184028 454346 255354 461942 347348 329873 324090 0 634052 337339 306630 142493 0 310217 492439 530208 370518 0 488251 0 0 410098 655422 0 517735 865391 413346 391014 2683296 1395838 1884416 2196951 4160251 3250955 2903893 2477512 2976160 429906 1848349 2067790 3707725 1319456 1710311 3066563 2329351 5702387 2551118 3489112 876529 994065 5021274 2168700 3354854 2766866 2578924 4105061 2920914 3147493 2304073 1004969 1143836 0 2978976 2400149 2797774 2106849 +(Gln->pyro-Glu)QDASNC(Carbamidomethyl)NSNSSISHEAVR MGYG000003351_04948;MGYG000000196_00570;MGYG000000054_01567;MGYG000001378_02415 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003351_04948 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1855752 1568930 1243968 1830679 0 1491729 2460206 1874697 1855143 1700084 3197967 1664589 0 0 1361642 1805533 2172316 0 0 1496162 1626564 1177575 0 1676358 1443391 1475162 0 0 1984200 0 0 1818244 1362594 1812650 1341198 1863958 1751004 1052268 472466 0 191721 506097 0 321312 394601 281688 196483 389447 318075 240250 0 0 169532 275819 326656 0 0 164123 427321 371179 0 386844 391762 368319 0 0 348909 0 0 477247 202782 420098 298987 228418 266243 193858 539004 760858 1246125 682211 0 405658 979817 563476 1053763 581608 858473 656095 0 0 697515 422694 778542 0 0 574513 566225 560410 0 698044 570333 749371 0 0 788932 0 0 485374 738391 639700 738059 983288 832081 1083080 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDATEQVVEGGMYQALK MGYG000001489_00789 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides goldsteinii|m__MGYG000001489 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,22WD0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001489_00789 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 367193 0 537012 343022 553170 0 0 0 0 0 0 0 0 343415 0 0 385283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334520 0 277942 0 402058 0 0 289672 0 387514 0 0 0 0 0 0 272651 0 0 0 0 0 0 248266 603589 0 0 0 0 0 0 354006 0 0 0 0 0 0 0 0 0 0 0 0 366469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333133 255367 0 0 0 0 0 0 0 0 772167 0 0 0 0 999238 841051 888524 897599 828478 0 707672 1010553 0 596866 567246 0 0 359706 708761 0 381118 0 730478 0 1068720 0 0 713059 577655 0 0 0 0 0 0 1030772 0 +(Gln->pyro-Glu)QDATNC(Carbamidomethyl)NSNSSISHEAVR MGYG000002549_00688;MGYG000001345_01173 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_00688 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1282128 1620065 0 0 0 0 0 0 3256676 0 0 0 1495108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 848886 681949 640987 0 0 978366 664518 0 0 1246510 0 0 0 791158 0 0 0 0 0 0 533189 0 519674 0 0 0 0 0 0 0 0 155401 0 0 0 0 591191 0 354978 0 0 0 0 0 0 0 0 1553924 0 0 0 0 0 0 0 0 0 0 0 0 1908950 0 0 0 0 0 0 0 0 528537 0 0 0 0 1070982 +(Gln->pyro-Glu)QDDNSSAKEEGNR MGYG000003697_01989;MGYG000002293_00403 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1629@1|root,COG4771@2|Bacteria,4NIXB@976|Bacteroidetes,2FNC3@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 beta-fructofuranosidase activity 1.0 scrL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_32C,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01989 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1446390 0 0 662984 0 0 0 0 1599355 0 2048031 0 0 0 0 0 0 0 0 1733414 0 1183454 0 0 0 0 0 0 0 0 1052267 0 0 0 0 1235382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDEAPAQTEQTAVVEEGGGLHK MGYG000000243_02202 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02202 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 9115832 9993030 24064773 12940884 13692250 12571542 11384146 9379734 11963690 8499581 8979634 8093934 11178512 11067563 9389902 14055559 12339150 8443098 9169081 7984695 10568849 8493062 8791417 13556209 7384154 9220331 9411748 8876745 10525101 13976562 19930963 11651080 26293639 12421169 9468758 11697014 8336577 28964010 3142538 2054343 3695849 0 5189308 3046657 2532499 4374425 4207476 3967769 3714277 3146745 5771564 4199021 3941315 4322660 4083180 1664774 3211469 3771048 3700558 3507434 2389595 2790750 3602655 3720467 3835738 1705233 2643537 3634302 2207109 3466428 3744676 3012385 3253129 3228337 3680716 2687178 5041948 3455157 5527392 5166359 7260460 6023473 6523755 3693412 7763897 3717945 5926536 6539653 6872598 4554533 4724404 5734399 4974113 7983471 4018707 4424810 4019785 3398677 7438939 5510375 0 5561116 4544512 5415291 5113236 3466639 6660068 3297220 3768098 1854713 5293555 6940064 5801149 6124094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262621 0 0 0 0 0 0 0 0 375445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211371 0 +(Gln->pyro-Glu)QDEAPAQTEQTAVVEEGGGLHKELK MGYG000000243_02202 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02202 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 5098834 9570526 48017642 8392602 22115987 9594505 5742094 11742497 8228518 6780386 9430260 7432146 10956993 9940167 5794440 10200109 10857165 4615966 9107758 6102388 5729219 7528492 3226809 9337723 6730844 7915109 5523813 3711298 6777828 7931631 25440766 14464409 38555001 7618507 7825239 4956342 6722531 37250899 499052 471708 576920 499065 1696384 583485 619706 592991 584285 949590 1105865 387224 1357439 478305 953713 947450 771634 0 336573 396453 430760 939972 0 656579 651042 520559 775816 0 892952 457496 393140 1135120 717141 648727 657299 552375 504252 723093 2571272 3466999 5005943 4453902 6286266 4495476 3420700 3278830 3814630 3352491 4806160 4203954 6495114 2534550 2273829 5129866 3445074 3931672 2781496 3066033 1958249 2231391 2579751 3574988 3171874 3616405 3070221 2222206 2691703 2153653 5149102 3041571 3156884 1502205 3230764 2930229 2983114 3020073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277394 0 0 0 353123 0 0 0 0 0 0 0 0 0 0 0 0 159050 0 0 0 150074 0 0 0 0 0 945796 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDELSHVFEK MGYG000000022_02144 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3WGES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_02144 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270253 0 0 0 0 265399 0 0 0 0 131465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265245 0 0 0 0 401837 0 0 0 0 302041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 487974 0 0 0 0 0 0 0 0 0 370286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 595452 0 0 0 0 1076979 0 0 0 0 801401 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDFDNKPVVNVSNSK MGYG000003681_01830 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG3746@1|root,COG3746@2|Bacteria,4NK1Y@976|Bacteroidetes,2FKYR@200643|Bacteroidia,4AW00@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 ko:K07221 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.5.1 1.0 - 1.0 - 1.0 Porin_O_P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_01830 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07221:oprO_P; phosphate-selective porin OprO and OprP 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5697017 1962779 4451521 5257382 0 0 0 0 0 4887730 0 0 0 5887326 0 0 0 0 6583721 0 0 0 0 0 0 5535433 4785120 0 4862726 0 2722328 0 3888449 0 0 4807560 6572064 4382386 279929 399054 0 0 0 0 0 0 0 364279 0 0 0 380553 0 0 0 0 696763 0 0 0 0 0 0 440569 0 0 393762 0 419499 0 0 0 0 518908 674584 168169 1662543 1395175 1052846 2125013 0 0 0 0 0 1482883 0 0 0 1862144 0 0 0 0 2499060 0 0 0 0 0 0 2215326 2022878 0 2114657 0 1057190 0 1205508 0 0 2421767 1989108 1037135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDFDNNPVVNVSNSK MGYG000001313_00702 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG3746@1|root,COG3746@2|Bacteria,4NK1Y@976|Bacteroidetes,2FKYR@200643|Bacteroidia,4AW00@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 ko:K07221 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.5.1 1.0 - 1.0 - 1.0 Porin_O_P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_00702 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07221:oprO_P; phosphate-selective porin OprO and OprP 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 944253 0 0 0 0 0 1526466 0 1134292 1176706 0 0 0 0 946831 0 1520320 0 0 0 0 0 0 0 0 601772 816118 0 1001518 0 1241939 0 0 0 0 1316085 1017398 0 599695 0 0 0 0 0 755796 0 234859 411176 0 0 0 0 467521 0 698055 0 0 0 0 0 0 0 0 880736 395374 0 896921 0 269696 0 0 0 0 845390 751854 0 0 0 0 0 0 0 459552 0 0 457263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610241 0 0 0 0 0 0 0 0 0 332195 0 +(Gln->pyro-Glu)QDGEPHSHLAAMAK MGYG000001714_01569 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus_A|s__Coprococcus_A catus|m__MGYG000001714 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,36DR1@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.1.108,1.3.8.1 1.0 ko:K00248,ko:K22430 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001714_01569 1.0 caffeoyl-CoA reductase. | short-chain acyl-CoA dehydrogenase. electron-bifurcating caffeoyl-CoA reductase. | unsaturated acyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. | One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. | a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1]|K22430:carC; caffeyl-CoA reductase-Etf complex subunit CarC [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 164204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 886027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDGPTALILSR MGYG000000107_04662;MGYG000000107_02891;MGYG000002494_04260;MGYG000002506_02537;MGYG000002323_03405 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,3XMMK@561|Escherichia 0.8 1236|Gammaproteobacteria 1.0 G 0.8 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate 1.0 tktA 1.0 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,ic_1306.c2990 0.8 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000107_04662 0.2 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582533 0 336364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93143 0 254333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 123083 0 259942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDHN(Deamidated)GFSHQDPGVTSVLLNK MGYG000000756_01025;MGYG000002459_00966;MGYG000003452_01631;MGYG000003683_00701;MGYG000002395_00808;MGYG000001292_01832;MGYG000002469_00856;MGYG000001490_00761 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000756_01025 0.125 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K01621:xfp, xpk; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 565617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3136679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 229807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDHNGFSHQDPGVTSVLLNK MGYG000000756_01025;MGYG000002459_00966;MGYG000003452_01631;MGYG000003683_00701;MGYG000002395_00808;MGYG000001292_01832;MGYG000002469_00856;MGYG000001490_00761 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000756_01025 0.125 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K01621:xfp, xpk; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22] 1.0 none 1.0 0 1502209 0 0 0 821607 0 0 0 0 0 0 0 0 0 0 0 391055 0 0 0 827673 351471 2416371 0 0 0 390061 0 0 2452389 0 0 0 0 0 0 0 0 1184329 0 0 0 1323841 0 0 0 0 0 0 0 0 0 0 0 3204633 0 0 0 0 1138109 2492954 0 0 0 2109473 0 0 2157567 0 0 0 0 0 0 0 0 870102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 953017 0 0 0 896485 248283 356284 0 0 0 537367 0 0 601236 0 0 0 0 0 0 0 0 473634 0 0 0 377470 0 0 0 0 0 0 0 0 0 0 0 347611 0 0 0 747489 0 876416 0 0 0 424484 0 0 463679 0 0 0 0 0 0 0 0 0 0 0 0 604536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDIHVEIC(Carbamidomethyl)SK MGYG000002312_02603;MGYG000000213_02733;MGYG000000184_01331;MGYG000000201_01344;MGYG000000002_00125;MGYG000000200_00582;MGYG000004785_00522;MGYG000001338_01040 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZ78@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family 1.0 rumA 1.0 - 1.0 2.1.1.190 1.0 ko:K03215 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Methyltransf_31,TRAM,tRNA_U5-meth_tr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002312_02603 0.125 23S rRNA (uracil(1939)-C(5))-methyltransferase. RNA uridine methyltransferase A. The enzyme specifically methylates uracil(1939) at C(5) in 23S rRNA.-!-The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues. S-adenosyl-L-methionine + uridine(1939) in 23S rRNA = 5-methyluridine(1939) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine. 1.0 1.0 1.0 1.0 - 1.0 K03215:rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190] 1.0 none 1.0 0 839169 0 0 0 0 0 0 0 0 0 0 0 0 0 518503 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1209097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1276541 0 0 0 0 0 0 0 0 0 0 0 0 0 893209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1201005 0 0 0 0 0 0 0 0 0 0 0 0 0 618440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1469338 0 0 0 0 0 0 0 0 0 0 0 0 0 471838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDKGDWAIMPR MGYG000001415_02124 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG3637@1|root,COG3637@2|Bacteria,4NXWX@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 M 1.0 Outer membrane protein beta-barrel domain 1.0 - 1.0 - 1.0 - 1.0 ko:K11934 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6.2.1 1.0 - 1.0 - 1.0 OMP_b-brl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_02124 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K11934:ompX; outer membrane protein X 1.0 none 1.0 1074975 1078805 0 844170 955419 903245 1144324 1491707 1166024 0 0 0 0 1047525 0 798741 1091070 0 0 795121 858153 730786 0 1281894 0 902268 0 0 0 0 1446437 1188840 0 1357195 0 1014053 858830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502469 0 431258 0 339687 0 0 503609 0 0 0 0 0 0 0 715434 0 0 0 0 147023 0 0 0 498926 0 0 0 0 462344 305879 0 254789 0 416012 501026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDKYAAEYAAK MGYG000000174_02977;MGYG000000105_02297;MGYG000002438_00594;MGYG000001780_04721;MGYG000001661_00375;MGYG000000224_01350;MGYG000001346_00809;MGYG000003681_00189;MGYG000001313_03103;MGYG000001370_00206;MGYG000002455_01654;MGYG000001489_05046 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0360@1|root,COG0360@2|Bacteria,4NQ9W@976|Bacteroidetes,2FSHK@200643|Bacteroidia,4AQYI@815|Bacteroidaceae 0.75 976|Bacteroidetes 0.75 J 0.75 Binds together with S18 to 16S ribosomal RNA 0.75 rpsF 0.75 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 0.75 - 1.0 ko:K02990 0.75 ko03010,map03010 0.75 M00178 0.75 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 0.75 - 1.0 - 1.0 - 1.0 Ribosomal_S6 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000174_02977 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.75 K02990:RP-S6, MRPS6, rpsF; small subunit ribosomal protein S6 0.75 none 1.0 335951 0 0 0 0 0 0 243454 0 0 356449 0 0 0 0 386300 0 0 0 0 259382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305815 0 270798 0 0 0 0 0 0 0 0 0 429412 0 0 0 0 315049 0 0 0 0 0 0 0 0 0 0 0 0 0 217176 0 447761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 145320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167849 0 0 0 0 0 0 0 0 0 0 428318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490986 0 0 0 895052 0 0 616971 602016 0 1248858 1003858 0 0 0 882813 0 0 0 0 1002112 0 0 0 0 701242 0 0 0 1321330 0 677261 0 649386 0 0 815633 0 +(Gln->pyro-Glu)QDLWFATK MGYG000000077_02534;MGYG000002992_01289;MGYG000004414_00496;MGYG000000076_00302;MGYG000000271_00043;MGYG000000650_00637;MGYG000004630_02109;MGYG000000378_02257;MGYG000002603_00810;MGYG000000146_00318;MGYG000002552_01282;MGYG000001637_01976;MGYG000000150_03719;MGYG000000489_00412;MGYG000002835_00491;MGYG000001687_00022;MGYG000004039_02130;MGYG000001528_02376;MGYG000002528_00841;MGYG000001311_03616;MGYG000000175_02007;MGYG000000099_02256;MGYG000000204_01085;MGYG000001314_02815;MGYG000000078_01372;MGYG000000154_00554;MGYG000000198_01314;MGYG000002133_00978;MGYG000002960_02247;MGYG000001645_01946;MGYG000003694_00268;MGYG000001374_01887;MGYG000002279_00786;MGYG000002523_00256;MGYG000001496_01079;MGYG000000135_00406;MGYG000003662_02146;MGYG000003147_02571;MGYG000000249_01884;MGYG000000139_01304;MGYG000000377_01969;MGYG000000562_01477;MGYG000002141_00952;MGYG000004271_00368;MGYG000002772_01345;MGYG000002517_01548;MGYG000000140_00828;MGYG000003695_00688;MGYG000003697_02877;MGYG000003427_02044;MGYG000004815_00205;MGYG000001770_01416;MGYG000000127_01878;MGYG000000312_00385;MGYG000004762_01414;MGYG000000038_01087;MGYG000000159_00506;MGYG000002080_02132;MGYG000000208_01206;MGYG000000080_02529;MGYG000004734_00467;MGYG000001056_02362;MGYG000000136_01284;MGYG000001714_01059;MGYG000001683_02046;MGYG000000179_01240;MGYG000001502_00893;MGYG000000272_02593;MGYG000002293_00899;MGYG000001781_00069;MGYG000001027_02002;MGYG000001607_00136;MGYG000002492_01799;MGYG000000268_00081;MGYG000002234_00368 domain d__Bacteria 1.0 COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia 0.21333333333333335 186801|Clostridia 0.8666666666666667 C 1.0 Belongs to the isocitrate and isopropylmalate dehydrogenases family 0.6533333333333333 icd 1.0 - 1.0 1.1.1.42 1.0 ko:K00031 1.0 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 1.0 M00009,M00010,M00173,M00740 1.0 R00267,R00268,R01899 1.0 RC00001,RC00084,RC00114,RC00626,RC02801 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Iso_dh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02534 0.013333333333333334 isocitrate dehydrogenase (NADP(+)). oxalosuccinate carboxylase. Unlike EC 1.1.1.41, oxalosuccinate can be used as a substrate.-!-In eukaryotes, isocitrate dehydrogenase exists in two forms: an NAD(+)-linked enzyme found only in mitochondria and displaying allosteric properties, and a non-allosteric, NADP(+)-linked enzyme that is found in both mitochondria and cytoplasm.-!-The enzyme from some species can also use NAD(+) but much more slowly. D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Glutathione metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids|Peroxisome 1.0 K00031:IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 46280 0 0 36222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 52805 0 0 0 0 0 0 0 170395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64326 0 0 0 0 154454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56479 +(Gln->pyro-Glu)QDNELFHLR MGYG000002478_04584;MGYG000004797_02790 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4409@1|root,COG4409@2|Bacteria,4NFNK@976|Bacteroidetes,2FNCR@200643|Bacteroidia,4AMGI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 BNR Asp-box repeat protein 1.0 nanH 1.0 - 1.0 3.2.1.18 1.0 ko:K01186 1.0 ko00511,ko00600,ko04142,map00511,map00600,map04142 1.0 - 1.0 R04018 1.0 RC00028,RC00077 1.0 ko00000,ko00001,ko01000,ko02042 1.0 - 1.0 GH33 1.0 - 1.0 BNR,BNR_2,BNR_3,BNR_assoc_N 1.0 3.2.1.18 1.0 GH33 1.0 GH33 1.0 GH33 1.0 MGYG000002478_04584 0.5 exo-alpha-sialidase. sialidase. The enzyme does not act on 4-O-acetylated sialic acids.-!-An endo-alpha-sialidase activity is listed as EC 3.2.1.129.-!-See also EC 4.2.2.15. Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. 1.0 1.0 1.0 1.0 Other glycan degradation|Sphingolipid metabolism|Lysosome 1.0 K01186:NEU1; sialidase-1 [EC:3.2.1.18] 1.0 none 1.0 0 0 0 0 0 0 0 258669 170954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248143 289746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 504749 438087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDPMALQR MGYG000000196_01218;MGYG000003266_00564;MGYG000000357_00601;MGYG000000003_01212;MGYG000001562_02334;MGYG000002905_01326;MGYG000000074_02347;MGYG000003423_00341;MGYG000000098_00251;MGYG000003279_01430;MGYG000002218_02599;MGYG000001420_01443;MGYG000000053_01169;MGYG000001567_00204 domain d__Bacteria 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,22UA3@171550|Rikenellaceae 0.42857142857142855 976|Bacteroidetes 0.8571428571428571 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_01218 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 597301 0 0 0 0 0 0 0 607205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 96306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564660 0 0 0 0 0 0 0 314515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670308 0 0 0 0 0 0 0 439476 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110937 0 0 0 0 0 0 0 200752 0 0 0 +(Gln->pyro-Glu)QDPSFGHPEK MGYG000000249_02121;MGYG000000216_00347;MGYG000000022_01381;MGYG000004733_00873;MGYG000000251_00145;MGYG000001338_00189;MGYG000001292_00841;MGYG000002469_01404;MGYG000002517_00467;MGYG000000133_01077;MGYG000000271_02405;MGYG000001300_00435 domain d__Bacteria 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia 0.4166666666666667 186801|Clostridia 0.8333333333333334 S 1.0 MCRA family 0.5833333333333334 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_02121 0.08333333333333333 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 - 1.0 K10254:ohyA, sph; oleate hydratase [EC:4.2.1.53] 1.0 none 1.0 394132 0 0 246757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257422 0 0 0 0 500188 1475847 342373 573984 0 332095 0 0 427789 0 0 0 0 0 0 0 0 0 0 149838 0 0 0 640015 0 325898 0 0 0 0 0 500744 301638 479781 0 0 153115 355394 0 533053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275832 0 0 0 0 0 0 0 0 0 344957 0 0 0 0 0 0 0 408424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 594110 905217 866072 0 0 447559 0 0 483547 0 0 0 0 0 0 0 0 0 0 521862 0 764952 0 668880 0 876172 0 0 0 0 0 763957 843679 830767 0 0 468611 688879 +(Gln->pyro-Glu)QDPSFGHPEKFC(Carbamidomethyl)SDIAK MGYG000000216_00347;MGYG000000251_00145;MGYG000001338_00189 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 S 1.0 Myosin-crossreactive antigen 0.6666666666666666 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000216_00347 0.3333333333333333 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 - 1.0 K10254:ohyA, sph; oleate hydratase [EC:4.2.1.53] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456659 0 0 0 0 236236 +(Gln->pyro-Glu)QDQKPPEPPK MGYG000000074_00226 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,2FPKW@200643|Bacteroidia,22UEA@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins 1.0 - 1.0 - 1.0 - 1.0 ko:K03832 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 2.C.1.1 1.0 - 1.0 - 1.0 TonB_C,VIT,VWA_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00226 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03832:tonB; periplasmic protein TonB 1.0 none 1.0 0 0 0 0 0 0 243392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 538840 0 0 0 0 0 0 0 0 0 0 0 337510 0 0 0 0 0 0 0 197969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458638 0 0 0 0 0 0 0 0 0 0 0 939955 0 0 0 0 0 0 0 540234 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDTNYYTPK MGYG000002478_04508 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG2885@1|root,COG2885@2|Bacteria,4P1BJ@976|Bacteroidetes,2FPC4@200643|Bacteroidia,4AMH8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 - 1.0 OMP_b-brl,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_04508 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03286:TC.OOP; OmpA-OmpF porin, OOP family 1.0 none 1.0 0 0 0 0 0 534518 0 0 0 0 0 0 0 0 0 0 0 0 0 376025 0 437887 260775 864708 0 0 0 318583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1276342 0 0 0 0 0 0 0 0 0 0 0 884291 0 1276949 0 1190198 1242401 1338986 0 0 0 916867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 817659 0 0 0 0 0 0 0 0 0 0 0 1383445 0 559223 0 646038 1167123 767840 0 0 0 914624 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271338 0 0 0 0 0 0 0 0 0 0 0 624119 0 357434 0 588292 771265 352005 0 0 0 429375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 811284 0 0 0 0 0 0 0 0 0 0 0 1872234 0 1278121 0 442241 1524987 558954 0 0 0 1471599 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDVEFKR MGYG000002960_00143;MGYG000003697_02150 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0246@1|root,COG0246@2|Bacteria,4NEMT@976|Bacteroidetes,2FP8Z@200643|Bacteroidia,4ATAV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Mannitol dehydrogenase Rossmann domain 1.0 uxuB 1.0 - 1.0 1.1.1.17,1.1.1.58,1.1.1.67 1.0 ko:K00009,ko:K00041,ko:K00045 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00631 1.0 R00868,R02555,R02703 1.0 RC00085 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Mannitol_dh,Mannitol_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002960_00143 0.5 mannitol-1-phosphate 5-dehydrogenase. | tagaturonate reductase. | mannitol 2-dehydrogenase. Tagaturonate dehydrogenase. | mannitol dehydrogenase. - D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + H(+) + NADH. | D-altronate + NAD(+) = H(+) + keto-D-tagaturonate + NADH. | D-mannitol + NAD(+) = D-fructose + H(+) + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K00009:mtlD; mannitol-1-phosphate 5-dehydrogenase [EC:1.1.1.17]|K00041:uxaB; tagaturonate reductase [EC:1.1.1.58]|K00045:E1.1.1.67, mtlK; mannitol 2-dehydrogenase [EC:1.1.1.67] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2724850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3182522 0 3246192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469653 0 339327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDVIDKFK MGYG000000233_01543;MGYG000000255_00343 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,21YPK@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000233_01543 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431494 463857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378444 166349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194034 140414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDVPSFRPGDTVEVK MGYG000002323_03125;MGYG000002477_01825;MGYG000003365.1_02196;MGYG000002494_04624;MGYG000001465_01866;MGYG000002500_03584;MGYG000000337_01318;MGYG000003360_03259;MGYG000003390_02497;MGYG000002535_00930;MGYG000002504_03064;MGYG000003883_03143;MGYG000002506_02124;MGYG000002515_00446;MGYG000002502_01722;MGYG000003372_01568;MGYG000000093_05408 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1Y8KB@135625|Pasteurellales 0.8823529411764706 135625|Pasteurellales 0.8823529411764706 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 0.8823529411764706 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_03125 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02884:RP-L19, MRPL19, rplS; large subunit ribosomal protein L19 1.0 none 1.0 1158461 0 366165 933984 0 974124 1258024 902782 1123496 984006 630853 1057405 0 841070 946442 343926 632000 0 520110 0 861395 1288310 0 779347 832550 661635 847738 0 863313 883557 0 519088 0 1074928 735164 973620 695619 739541 1911793 1518556 2071290 1855405 0 3929104 2059531 2017295 1989452 2942269 1055042 1876600 0 2314189 1995275 1525052 2401458 0 2675518 0 2313088 4432919 0 2969127 2807951 1926294 1956409 0 2702544 2607957 1168977 1683704 2360248 1746063 1812655 1616189 1586872 1917680 700984 515555 1047221 738607 0 1856102 0 870534 935542 1119447 556271 755939 0 877776 897503 865101 734774 0 1059774 0 1096728 1077700 0 1478178 1141828 799628 1019388 0 781588 984178 664494 0 830906 0 973509 1225901 917451 0 1113538 549990 461949 791996 0 871747 1065099 1301438 487155 1172893 526624 615225 0 1017437 953740 556542 625932 0 619325 0 1307441 884149 0 547412 1218392 1181422 1045847 0 686259 612321 0 1079499 303684 1835808 1775722 1278985 916341 549532 0 0 0 0 0 0 0 0 0 0 0 355309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDVTGTIHANQGTQK MGYG000002293_00077 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,2FNNB@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Alpha-L-arabinofuranosidase domain protein 1.0 abf2 1.0 - 1.0 3.2.1.55 1.0 ko:K01209 1.0 ko00520,map00520 1.0 - 1.0 R01762 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH51 1.0 - 1.0 Alpha-L-AF_C 1.0 3.2.1.55 1.0 GH51 1.0 GH51 1.0 GH51 1.0 MGYG000002293_00077 1.0 non-reducing end alpha-L-arabinofuranosidase. arabinosidase. Acts on alpha-L-arabinofuranosides, alpha-L-arabinans containing (1,3)- and/or (1,5)-linkages, arabinoxylans and arabinogalactans.-!-Some EC 3.2.1.23 and EC 3.2.1.38 enzymes also hydrolyze alpha-L- arabinosides. cf. EC 3.2.1.185.-!-Formerly EC 3.2.1.79. Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 K01209:abfA; alpha-L-arabinofuranosidase [EC:3.2.1.55] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18610611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1459641 0 0 0 0 2125057 0 0 0 0 606164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDVTGTIHASQGTQK MGYG000003697_02024 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG3534@1|root,COG3534@2|Bacteria,4NECK@976|Bacteroidetes,2FNNB@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Alpha-L-arabinofuranosidase domain protein 1.0 abf2 1.0 - 1.0 3.2.1.55 1.0 ko:K01209 1.0 ko00520,map00520 1.0 - 1.0 R01762 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH51 1.0 - 1.0 Alpha-L-AF_C 1.0 3.2.1.55 1.0 GH51 1.0 GH51 1.0 GH51 1.0 MGYG000003697_02024 1.0 non-reducing end alpha-L-arabinofuranosidase. arabinosidase. Acts on alpha-L-arabinofuranosides, alpha-L-arabinans containing (1,3)- and/or (1,5)-linkages, arabinoxylans and arabinogalactans.-!-Some EC 3.2.1.23 and EC 3.2.1.38 enzymes also hydrolyze alpha-L- arabinosides. cf. EC 3.2.1.185.-!-Formerly EC 3.2.1.79. Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 K01209:abfA; alpha-L-arabinofuranosidase [EC:3.2.1.55] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1147459 0 0 0 0 1549245 0 0 0 0 893947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QDVVTFNEKPVQIESK MGYG000002438_00809 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,2FP7M@200643|Bacteroidia,22WKX@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the pseudouridine synthase RsuA family 1.0 rluB 1.0 - 1.0 5.4.99.22 1.0 ko:K06178 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03009 1.0 - 1.0 - 1.0 - 1.0 PseudoU_synth_2,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00809 1.0 23S rRNA pseudouridine(2605) synthase. - Pseudouridine synthase RluB converts uridine(2605) of 23S rRNA to pseudouridine. uridine(2605) in 23S rRNA = pseudouridine(2605) in 23S rRNA. 1.0 1.0 1.0 1.0 - 1.0 K06178:rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553062 0 0 0 0 0 0 0 0 519705 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEAEAFYAVHR MGYG000003352_00067;MGYG000003022_00269 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG0105@1|root,COG0105@2|Bacteria,1R9ZA@1224|Proteobacteria,2VQ2J@28216|Betaproteobacteria,1KKKW@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 F 1.0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate 1.0 ndk 1.0 - 1.0 2.7.4.6 1.0 ko:K00940 1.0 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 1.0 M00049,M00050,M00052,M00053 1.0 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000,ko04131 1.0 - 1.0 - 1.0 - 1.0 NDK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003352_00067 0.5 nucleoside-diphosphate kinase. nucleoside diphosphokinase. Many nucleoside diphosphates can act as acceptors.-!-Many ribo- and deoxyribonucleoside triphosphates can act as donors. (1) a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP. (2) a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP. 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites|MAPK signaling pathway - plant 1.0 K00940:ndk, NME; nucleoside-diphosphate kinase [EC:2.7.4.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 246913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 455188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEAIYKK MGYG000001306_03308 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_03308 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141430 0 0 0 0 2794921 0 0 0 0 2185913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239078 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEAKEEPKEEGFVFTTVK MGYG000000243_01742 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia,4AKZY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase C1-like family 1.0 pepC 1.0 - 1.0 3.4.22.40 1.0 ko:K01372 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_C1,Peptidase_C1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01742 1.0 bleomycin hydrolase. aminopeptidase C (Lactococcus lactis). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain.-!-Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity.-!-Known from bacteria as well as eukaryotic organisms.-!-Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates.-!-Belongs to peptidase family C1. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. 1.0 1.0 1.0 1.0 - 1.0 K01372:BLMH, pepC; bleomycin hydrolase [EC:3.4.22.40] 1.0 none 1.0 1776283 2147313 6017045 2400219 3616299 1775163 2561368 0 2172317 1649974 1833656 0 2194470 2172003 1716974 2111515 2235731 0 2015705 1535138 0 1876803 0 2529020 1804751 2161879 2114495 0 0 0 5363084 2756420 7211398 2638205 0 2263176 1938898 6720679 417512 281141 447902 513714 800908 490901 357489 0 535475 548297 452092 0 438440 445875 712940 728943 627609 0 276057 462535 0 526734 0 359626 548809 660807 691321 0 0 0 304956 658086 582233 529992 0 448132 485432 336416 1053692 833492 1045800 970750 1375434 1112475 1016345 0 1165199 868345 944926 0 1606848 1022854 889579 1315649 722111 0 979024 279625 0 714983 0 360263 896809 423588 998990 0 0 0 1148068 727503 497729 348233 0 409266 1071899 917042 231507 0 0 0 0 0 0 0 336688 0 0 0 0 411637 306572 0 0 0 0 0 0 531857 0 0 833854 0 0 0 0 0 0 0 278328 0 0 0 512207 0 0 0 0 119938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188627 0 232575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEAKPAAAPK MGYG000000003_00808 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 2EGII@1|root,33AAP@2|Bacteria,4NXMZ@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4890,LTXXQ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_00808 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 3138586 0 0 0 0 0 0 0 0 0 0 2132353 0 0 0 4523155 0 4233297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212575 0 0 0 0 0 0 0 0 0 0 121329 0 0 0 142696 0 253734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721253 0 142978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 694866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEAPIHISNLNPVDPK MGYG000001364_02743;MGYG000000042_01080;MGYG000001306_02671;MGYG000001789_00119;MGYG000001925_01443 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0198@1|root,COG0198@2|Bacteria,4NSTI@976|Bacteroidetes,2FT5V@200643|Bacteroidia,22Y4Z@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit 1.0 rplX 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02895 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KOW,ribosomal_L24 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001364_02743 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02895:RP-L24, MRPL24, rplX; large subunit ribosomal protein L24 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656422 0 0 0 0 996174 0 0 0 0 867010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEATETAVEGGMYQALK MGYG000002033_00945;MGYG000000138_04126 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,22WD0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002033_00945 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 978315 1217414 1211313 1316488 1209337 931933 1877463 1517141 1628050 0 1188192 1604345 904357 1263758 444841 0 0 461866 1387475 997560 1434549 861942 1321062 1314436 1141922 1554754 1247705 1494787 0 0 0 1878012 1292311 1406862 1634405 1464265 1242974 1011912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449622 0 0 0 0 435609 0 0 0 0 0 0 0 0 0 0 1052549 757751 1095554 1145663 1619471 1285256 1067144 1037540 1144491 0 1047992 1447399 1043181 973533 975283 0 0 930172 1005386 922903 542919 340767 1058797 1031499 928719 784750 935815 794764 0 0 0 917237 698051 774955 1145976 1096883 865159 856885 1540227 1496860 1493220 1290622 1334261 1488957 1313196 1428267 1551720 0 1206153 1540952 1140705 1302405 1410459 0 0 872545 1390447 1177253 645480 1174389 1223845 1408233 1394806 1385532 1531649 813700 0 0 0 2331639 1494079 2147313 1771474 1838516 1820390 1458541 656274 528926 630512 662394 344504 586914 769280 690727 628623 0 500639 437885 960404 471374 412286 0 0 0 426347 572930 210441 468855 1831832 309335 674632 647503 618369 0 0 0 0 711043 525404 951138 635488 552996 500939 516905 +(Gln->pyro-Glu)QEDIKVK MGYG000000074_02170 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia,22UGQ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Biopolymer transport protein ExbD/TolR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ExbD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02170 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111170 0 0 0 0 0 0 1250839 0 0 0 391264 0 0 0 0 0 0 1087493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343693 0 0 0 0 0 0 0 0 334876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 536202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1536315 1316832 0 0 0 0 0 1285673 0 0 0 1221853 0 0 0 0 0 0 1202231 0 +(Gln->pyro-Glu)QEDNQVVVTRPNDLKK MGYG000002528_01854 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center 1.0 rplF 1.0 - 1.0 - 1.0 ko:K02933 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01854 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02933:RP-L6, MRPL6, rplF; large subunit ribosomal protein L6 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEFKPQVGFSNEAGYK MGYG000000138_03404;MGYG000000044_03456 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG2885@1|root,COG2885@2|Bacteria,4NKQC@976|Bacteroidetes,2FRBK@200643|Bacteroidia,22X13@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 - 1.0 GO:0001871,GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0006810,GO:0008150,GO:0015267,GO:0015288,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030246,GO:0030247,GO:0051179,GO:0051234,GO:0055085 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000138_03404 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 1597604 0 0 0 0 0 0 0 0 0 0 0 0 772258 0 0 0 0 0 0 1153668 0 0 0 1272224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 229675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1390365 0 0 0 0 0 0 0 0 0 0 0 0 705576 0 0 0 0 0 0 1214900 0 0 0 1030692 0 0 0 0 0 0 0 0 0 0 0 0 0 998441 0 0 0 0 0 0 0 0 0 0 0 0 1277495 0 0 0 0 0 0 1284049 0 0 0 1234376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541220 0 0 0 0 0 0 379952 0 0 0 281868 0 0 +(Gln->pyro-Glu)QEGTLGKPVASDYQR MGYG000002438_00500 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,2324H@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 MGYG000002438_00500 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 973680 0 0 0 0 766511 0 0 0 0 810920 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEHDAIC(Carbamidomethyl)DWVFDKDPDFK MGYG000000022_02380 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG2414@1|root,COG2414@2|Bacteria,1TPT9@1239|Firmicutes,2481Q@186801|Clostridia,3WQA7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Aldehyde ferredoxin oxidoreductase, N-terminal domain 1.0 - 1.0 - 1.0 1.2.7.5 1.0 ko:K03738,ko:K19515 1.0 ko00030,ko00362,ko01100,ko01120,ko01200,map00030,map00362,map01100,map01120,map01200 1.0 M00309,M00541 1.0 R08571,R10961 1.0 RC00242,RC01839 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AFOR_C,AFOR_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_02380 1.0 aldehyde ferredoxin oxidoreductase. tungsten-containing aldehyde ferredoxin oxidoreductase. This is an oxygen-sensitive enzyme.-!-Catalyzes the oxidation of aldehydes (including crotonaldehyde, acetaldehyde, formaldehyde and glyceraldehyde) to their corresponding acids.-!-However, it does not oxidize glyceraldehyde 3-phosphate (see EC 1.2.7.6).-!-Can use ferredoxin or methylviologen but not NAD(P)(+) as electron acceptor. an aldehyde + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = a carboxylate + 3 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Benzoate degradation|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03738:aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]|K19515:bamB; benzoyl-CoA reductase subunit BamB [EC:1.3.-.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 514695 0 0 0 0 182143 0 0 0 0 657578 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302109 0 0 0 0 341783 0 0 0 0 275363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2244370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QELDLLK MGYG000002478_02020 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,4AKEY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02020 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QENPNKPDNIIEK MGYG000002279_01754;MGYG000000038_00954 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,27V7M@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_01754 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 965657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 758816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QENQLTAIR MGYG000001315_01374;MGYG000000038_01351;MGYG000001338_03290;MGYG000004733_00268;MGYG000002298_02804;MGYG000000171_02327;MGYG000000212_02591;MGYG000000200_02310;MGYG000000184_01074;MGYG000000213_01826;MGYG000000133_00794 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3Y1DY@572511|Blautia 0.9090909090909091 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 0.9090909090909091 - 1.0 - 1.0 - 1.0 ko:K02058 1.0 - 1.0 M00221 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1.2 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01374 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02058:ABC.SS.S; simple sugar transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 384093 0 0 0 0 0 0 0 0 0 742469 0 0 0 0 428098 0 0 0 0 474351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 649440 0 0 0 0 412621 0 0 0 0 713688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159227 0 0 0 0 0 0 0 0 0 171875 0 0 0 0 315597 0 0 0 0 149655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436419 0 0 0 0 0 0 0 0 0 343087 0 0 0 0 806014 0 0 0 0 1208246 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEPGIK MGYG000000212_02158 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3XZRM@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 8.87 1.0 glgD 1.0 - 1.0 2.7.7.27 1.0 ko:K00975 1.0 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 1.0 M00565 1.0 R00948 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Hexapep,NTP_transferase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_02158 1.0 glucose-1-phosphate adenylyltransferase. ADP-glucose synthase. - alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate. 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biofilm formation - Escherichia coli 1.0 K00975:glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 70335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QESNAAIR MGYG000000196_00914 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 2924H@1|root,2ZPPH@2|Bacteria,4NNST@976|Bacteroidetes,2FR7C@200643|Bacteroidia,4AMVX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG27363 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4251 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00914 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 874537 0 0 0 0 864902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEVELTKEEK MGYG000001364_00890;MGYG000003693_02102 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2924H@1|root,2ZPPH@2|Bacteria,4NNST@976|Bacteroidetes,2FR7C@200643|Bacteroidia,4AMVX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG27363 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4251 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001364_00890 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1865167 0 0 0 0 3026084 0 0 0 0 1761124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 655887 0 0 0 0 0 0 0 0 0 944669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEVELTKEEKK MGYG000003693_02102 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 2924H@1|root,2ZPPH@2|Bacteria,4NNST@976|Bacteroidetes,2FR7C@200643|Bacteroidia,4AMVX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG27363 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4251 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_02102 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 891020 0 0 0 0 986755 0 0 0 0 818058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEVKEEGK MGYG000000243_02431;MGYG000002171_00876 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2885@1|root,COG2885@2|Bacteria,4NKM0@976|Bacteroidetes,2FP8P@200643|Bacteroidia,4AN93@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 COG2885 Outer membrane protein and related peptidoglycan-associated 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HALZ,OMP_b-brl,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02431 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1399690 1465892 6976061 3182870 2893948 1549714 2541851 0 2299709 0 2815735 2394106 3180031 1928870 2871586 2432787 2622152 2664470 2460133 0 0 2353440 2216732 3019106 2315874 2182056 1642296 1752815 2388723 2074799 6432049 0 6012654 2322967 0 2277554 2088405 7596490 608284 392016 585595 1080611 1547684 733597 1254227 0 381766 0 657136 377820 1397692 745223 679147 990663 413998 214363 433996 0 0 741659 465203 660248 635337 802365 843235 0 635520 824157 639328 0 819272 838207 0 717999 644191 580179 830804 1178770 1473414 1921173 1899065 1490808 985841 0 1497591 0 1473200 1354052 2498680 1035143 1284400 2103061 1017604 184069 1780885 0 0 1393528 975159 1287333 1363993 2031049 1186162 557590 1495327 1383046 1783720 0 1401502 811193 0 1798558 1540601 1893733 122518 165244 181960 0 0 88056 0 0 0 0 204716 324661 0 0 0 0 186173 243874 0 0 0 243378 140202 0 93184 0 0 6970 0 0 154051 0 0 0 0 0 243576 0 0 0 0 214836 0 0 0 0 0 0 0 83507 0 0 0 0 54406 0 0 0 0 108311 0 204189 0 0 189262 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEWADGGKEK MGYG000002517_00541;MGYG000000154_01283 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00541 0.5 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 593892 278109 0 641125 234566 264337 0 564322 335309 719186 0 308500 0 0 820498 330490 503831 0 714490 555354 835373 0 0 0 729609 470372 638808 0 190597 467043 0 0 0 429513 418676 441937 422385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170673 0 0 0 226854 0 0 250900 0 0 0 255774 0 410569 0 306466 0 277045 401993 189789 0 0 320188 407160 337988 0 0 0 281751 691118 296158 0 0 335910 293675 0 0 346766 501466 0 493374 342241 4362590 1186907 1255284 5199218 2988373 1615230 3111109 4763869 5663828 2802058 1749810 2512703 0 5892227 4562257 1835464 3846623 0 4404079 5599241 2665102 428727 0 431275 6572733 5076550 6275164 0 1765841 4993077 1405808 1913239 1192889 1477633 5010647 3812250 5477986 1180635 2930183 3019716 4182031 0 876330 2504700 3517961 2884090 2931403 4835203 2996426 3749645 0 5311570 5366512 3151988 4060561 0 3738774 1740495 4868815 2628934 0 2450949 6298530 5042886 4941878 0 923483 1991759 2473563 950560 4960061 4444558 4917581 7013188 4642589 3409114 +(Gln->pyro-Glu)QEWAEGGKDK MGYG000000018_00070;MGYG000003422_00257;MGYG000002492_00658;MGYG000001707_00051;MGYG000001319_02236 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000018_00070 0.2 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 270719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454982 0 0 0 0 445469 0 0 0 0 452790 0 0 0 0 242322 0 0 0 0 0 0 0 476980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1399000 0 0 0 0 1979212 0 0 0 0 506283 0 0 0 0 726805 0 0 1141730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 730903 0 0 0 0 1211531 0 0 0 0 1308079 0 0 0 0 1049818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEWAEGGKEK MGYG000003486_02523;MGYG000000245_02020 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003486_02523 0.5 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 484144 0 0 0 0 0 0 0 0 0 0 496502 479740 0 0 0 0 0 0 0 0 0 0 0 0 617350 0 0 0 593555 0 0 0 0 0 0 681195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEWAEN(Deamidated)GLAK MGYG000002619_02238;MGYG000001300_00294;MGYG000003899_01135;MGYG000000022_01323;MGYG000001255_01113;MGYG000002272_01496;MGYG000003166_01335;MGYG000002040_01716 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002619_02238 0.125 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 0 243895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 713013 0 0 0 0 0 0 0 378835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 782521 0 0 0 0 0 0 0 844531 0 0 0 0 0 0 1307563 0 0 0 0 0 0 0 758071 0 0 0 985073 952630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416462 0 0 0 0 0 0 0 540489 0 0 0 0 0 0 614609 0 0 0 0 0 0 0 0 0 0 0 512208 214160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEWAENGLAK MGYG000002619_02238;MGYG000001300_00294;MGYG000003899_01135;MGYG000000022_01323;MGYG000001255_01113;MGYG000002272_01496;MGYG000003166_01335;MGYG000002040_01716 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002619_02238 0.125 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 623117 646153 671378 789986 243901 498976 468440 0 518080 0 0 742837 0 527707 0 0 381748 554639 692987 657857 0 671625 728176 518130 711918 925449 737055 617752 0 0 514264 274749 671067 918175 0 756056 570968 755193 1145954 1709162 1403828 1357274 922798 1501722 1832431 0 1495977 0 0 1314990 0 1258514 0 0 1082410 869184 1817660 1739314 0 914208 1087550 1449152 1681328 963606 1380626 1688186 0 0 2058751 1115898 1195332 906546 0 828934 890177 1199221 346775 192692 296440 430731 0 258481 553367 0 327297 0 0 447499 0 416298 0 0 163901 806843 176048 301543 0 0 755412 335091 260161 532911 272600 802284 0 0 614074 156512 299963 376286 0 393154 453461 368436 509652 545609 664874 620825 775071 606121 900633 0 759639 0 0 937019 0 671843 0 0 482521 418063 678193 699785 0 0 0 424500 367465 692017 450646 0 0 0 828381 552041 796576 452488 0 571472 655461 756305 0 219908 0 0 0 0 0 0 0 0 0 132824 0 122660 0 0 0 858349 172983 0 0 0 914426 0 125083 0 0 141422 0 0 0 271090 300083 167291 0 158439 218723 279671 +(Gln->pyro-Glu)QEYNLSLQGGNAK MGYG000002478_01935 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01935 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489334 0 0 0 0 0 0 0 759794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 214643 0 0 0 0 0 0 0 292488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QEYQPQVGFSNEAGYK MGYG000002438_03857 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG2885@1|root,COG2885@2|Bacteria,4NKQC@976|Bacteroidetes,2FRBK@200643|Bacteroidia,22X13@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 - 1.0 GO:0001871,GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0006810,GO:0008150,GO:0015267,GO:0015288,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030246,GO:0030247,GO:0051179,GO:0051234,GO:0055085 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03857 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 356659 0 0 0 0 0 0 0 0 0 0 520120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304844 0 0 0 0 296901 529760 561802 543416 0 662085 502524 623713 812513 0 787174 0 2384239 0 600189 0 1000289 0 0 687091 380356 4013331 765956 372506 655411 0 844303 0 0 563522 2693687 629132 0 840328 574558 739243 775029 930190 684319 917806 0 0 0 596863 929718 527511 417264 0 504261 0 1750389 0 0 0 0 0 1185231 0 0 3117007 0 0 635094 0 406616 0 0 0 2384750 927784 0 0 0 705080 697619 676778 0 619617 519874 355566 0 492146 342231 359827 533181 0 453702 0 1319406 0 416950 0 501537 0 0 477668 490662 5296053 0 0 0 0 0 0 0 236358 1712868 311238 0 519154 474959 593348 509320 429946 0 1432314 1715216 1375152 0 2776472 1660239 1585848 1679423 0 1682876 0 4058438 0 1467220 0 2227566 0 2063736 1421117 1522203 4945252 625966 1900131 1560875 0 1696979 0 1371521 1573997 5886848 1711759 0 1210639 1437969 1764834 1580377 1665227 1265107 +(Gln->pyro-Glu)QFAETEVKPLAQETDETEVFPAETVAK MGYG000001186_01721;MGYG000002492_00659;MGYG000002670_01509 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001186_01721 0.3333333333333333 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 327268 0 336062 0 0 0 0 0 0 0 377696 0 0 270173 0 237915 0 0 0 0 0 0 250043 0 0 0 0 0 0 0 235510 0 0 0 0 0 0 0 681775 0 1197436 0 0 0 0 0 761010 0 611319 0 0 399920 0 2539888 0 422888 0 0 1824219 0 624528 0 0 2458353 0 0 560107 474141 733539 0 0 0 0 966960 0 0 3235710 0 1021608 0 0 0 0 0 1232811 0 1655488 0 0 1764799 0 779625 0 692184 0 0 1040243 0 801053 0 0 1779218 0 0 1332560 1045991 3528873 0 0 0 0 2628654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141937 0 422009 0 0 0 0 387876 0 0 0 0 377587 0 0 286294 0 0 0 0 0 0 213852 0 0 0 0 1498035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QFAFTLR MGYG000002494_02439 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1970@1|root,COG1970@2|Bacteria,1RHG8@1224|Proteobacteria,1S3PD@1236|Gammaproteobacteria,3X2BS@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 M 1.0 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell 1.0 mscL 1.0 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 1.0 - 1.0 ko:K03282 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.22.1 1.0 - 1.0 - 1.0 MscL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02439 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03282:mscL; large conductance mechanosensitive channel 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193832 164608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125893 0 0 0 0 106530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QFAKDNK MGYG000000251_02358;MGYG000001319_00507;MGYG000000002_00433 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_02358 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QFDAVMEHINHANDLGTTK MGYG000002517_02762 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0840@1|root,COG0840@2|Bacteria,1TY0J@1239|Firmicutes,24DGH@186801|Clostridia 1.0 186801|Clostridia 1.0 NT 1.0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). 1.0 - 1.0 - 1.0 - 1.0 ko:K03406 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 MCPsignal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02762 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03406:mcp; methyl-accepting chemotaxis protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403276 0 0 0 0 0 0 0 0 0 0 638783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174821 0 +(Gln->pyro-Glu)QFDDRYMMLK MGYG000000255_01557 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36EI7@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01557 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 1387244 741107 1003064 0 0 0 0 0 0 0 0 0 762966 766042 0 0 0 0 0 518851 0 694490 0 0 0 0 0 958335 0 0 0 0 0 0 0 0 0 0 1440556 756967 1500854 0 0 0 0 0 0 0 0 0 1088172 798661 0 0 0 0 0 1322482 0 1367328 0 0 0 0 0 984791 0 0 0 0 0 0 0 0 0 0 664517 474823 636761 0 0 0 0 0 0 0 0 0 451328 391213 0 0 0 0 0 632900 0 472610 0 0 0 0 0 542904 0 0 0 0 0 0 0 0 0 0 920516 479127 435888 0 0 0 0 0 0 0 0 0 564177 573829 0 0 0 0 0 629954 0 650054 0 0 0 0 0 684728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QFDGMTFR MGYG000004479_01116;MGYG000002560_01730;MGYG000001789_02092;MGYG000000042_02678;MGYG000003693_00676;MGYG000001306_03824;MGYG000001337_03683;MGYG000002478_04117;MGYG000003221_00209;MGYG000001364_01848;MGYG000001835_01025;MGYG000000243_00095;MGYG000004763_00186 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000004479_01116 0.07692307692307693 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 146516 0 501698 0 426224 236152 0 311224 95759 325578 229279 0 424768 237700 0 310343 0 181541 0 0 307428 275219 307795 408442 0 259080 226885 240786 0 0 316251 0 602543 0 204397 0 309329 476625 143005 0 224436 0 363027 255260 0 322890 213944 337052 286189 0 453743 227723 0 420924 0 503439 0 0 190697 209390 590106 190017 0 218777 235575 526071 0 0 72335 0 220889 0 270698 0 257541 169651 0 0 88161 0 189490 80122 0 0 69726 74134 102802 0 296549 67340 0 244559 0 229719 0 0 58627 64960 335165 98162 0 76032 140245 213393 0 0 94084 0 0 0 0 0 88307 65842 50000 0 75150 0 0 104125 0 66979 127738 90365 65807 0 156520 83128 0 0 0 100094 0 0 255724 0 0 72139 0 102781 199305 127554 0 0 91070 0 90761 0 265305 0 119323 0 276061 0 216941 0 708765 286663 0 302642 312695 184852 303891 0 308013 301124 0 452812 0 482811 0 0 159279 105502 455905 147302 0 94917 174435 578014 0 0 150773 0 137895 0 242163 0 0 305857 +(Gln->pyro-Glu)QFEDGYHIIK MGYG000004718_00706;MGYG000000177_01042;MGYG000000016_02517 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36EI7@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004718_00706 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 1807828 1674957 1817293 0 0 1730729 0 0 0 2509191 0 0 0 0 2240264 0 2250475 0 0 2010300 2021125 1962192 0 1296539 0 2104725 1790680 0 1803957 0 1009129 0 1591952 1991864 1816593 0 1390463 1360210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 785644 1120474 1008894 0 0 492991 0 0 0 938916 0 0 0 0 1237631 0 398153 0 0 1141082 687882 585801 0 655005 0 574812 1229294 0 1188024 0 616932 0 1055180 650764 1297163 0 545832 1065206 864643 385837 1397056 0 0 947960 0 0 0 1455214 0 0 0 0 808937 0 501299 0 0 730774 229835 1154962 0 2054197 0 918750 589375 0 1161619 0 1304019 0 1902120 1419653 940152 0 684051 1446733 401997 235580 337055 0 0 0 0 0 0 809661 0 0 0 0 746321 0 370123 0 0 304926 434792 0 0 186160 0 542390 393169 0 761757 0 755887 0 428811 563996 624764 0 455627 364970 +(Gln->pyro-Glu)QFEDRYHVLK MGYG000000164_00687;MGYG000000127_04021;MGYG000001315_01867;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_00687 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 1606093 1746402 1522857 459970 2413040 1827059 1570373 3017988 1987300 3098730 1706339 1428464 3778255 1854127 3105686 2578755 1904563 0 1738444 2550927 2536154 1818240 0 674621 3029670 1856672 1976931 0 1637009 1895525 612820 1274633 868630 1966398 2636533 1414081 1555640 894140 503382 807021 781649 557359 950876 612979 562726 661256 481570 565966 517373 263709 851554 349567 492084 507500 264920 0 532232 527934 415264 240734 0 741150 720043 532039 696188 0 846182 421645 921607 1071440 694231 689372 725743 516051 454111 1064307 451965 483873 288499 176926 165726 139892 251371 577542 247610 367198 163980 356901 435532 277414 417782 453445 220530 0 208227 426948 322663 342069 0 331706 485472 364031 457845 0 327838 411912 253893 366307 577431 85627 533253 226442 426834 292806 190769 331086 886655 202754 421920 92050 307179 253089 69890 238668 494275 655049 553459 225302 174515 523616 141284 0 277694 87796 235205 603843 0 432444 95772 173948 270450 0 85570 381655 395723 328409 850605 0 322094 87632 63669 1092240 239299 0 808594 387082 102661 363422 90255 189950 185661 162580 220728 317126 174148 306932 236133 166617 250308 0 182050 0 224107 127254 0 67359 246524 293476 256144 0 220753 0 242498 212536 929801 320386 104124 211025 366492 943981 +(Gln->pyro-Glu)QFFDEHQATYPTR MGYG000002506_02758 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1882@1|root,COG1882@2|Bacteria,1MWYE@1224|Proteobacteria,1RWKK@1236|Gammaproteobacteria,3XMIN@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 formate acetyltransferase 1.0 tdcE 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016020,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017144,GO:0019541,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0043875,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046459,GO:0070689,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcSMS35_1347.EcSMS35_3410 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02758 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311990 0 0 0 0 0 0 0 362996 0 0 0 417544 0 0 0 0 0 0 298498 0 0 0 137222 0 0 0 0 0 379701 0 0 0 0 0 0 0 0 177880 278881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276397 0 0 0 0 0 0 0 0 519895 0 0 0 0 0 0 0 401367 0 0 0 778085 0 0 0 0 0 0 507360 0 0 0 582589 0 0 0 0 0 833219 0 0 0 0 0 0 0 0 902107 674107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QFGKPVQVGIIIPK MGYG000000142_00004;MGYG000003695_01166;MGYG000002312_02616;MGYG000001338_01045;MGYG000001027_01800;MGYG000004296_01828;MGYG000000216_03624 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,3XYTN@572511|Blautia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 Methylenetetrahydrofolate reductase 1.0 metF 1.0 - 1.0 1.5.1.20 1.0 ko:K00297 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 1.0 M00377 1.0 R01224,R07168 1.0 RC00081 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MTHFR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_00004 0.14285714285714285 methylenetetrahydrofolate reductase [NAD(P)H]. MTHFR. A flavoprotein (FAD).-!-The enzyme catalyzes the reversible conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, playing an important role in folate metabolism by regulating the distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis.-!-This enzyme, characterized from Protozoan parasites of the genus Leishmania, is unique among similar characterized eukaryotic enzymes in that it lacks the C-terminal allosteric regulatory domain (allowing it to catalyze a reversible reaction) and uses NADH and NADPH with equal efficiency under physiological conditions. cf. EC 1.5.1.53, EC 1.5.1.54, and EC 1.5.7.1.-!-Formerly EC 1.1.1.68, EC 1.1.1.171, EC 1.1.99.15 and EC 1.7.99.5. (1) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH. (2) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Antifolate resistance 1.0 K00297:metF, MTHFR; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 756352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QFHGYFNK MGYG000004681_01028;MGYG000003266_00909;MGYG000002947_00046;MGYG000002919_01817;MGYG000000188_01569;MGYG000001718_00229;MGYG000002970_01274;MGYG000001642_00447;MGYG000002775_00112 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CUFQ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 - 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004681_01028 0.1111111111111111 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QFHLVDSEHEINNLLK MGYG000002478_02180;MGYG000002560_01469;MGYG000000243_00722;MGYG000002291_01779;MGYG000001750_01197 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0104@1|root,COG0104@2|Bacteria,4NGRZ@976|Bacteroidetes,2FM8A@200643|Bacteroidia,4AMZZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP 1.0 purA 1.0 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 6.3.4.4 1.0 ko:K01939 1.0 ko00230,ko00250,ko01100,map00230,map00250,map01100 1.0 M00049 1.0 R01135 1.0 RC00458,RC00459 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Adenylsucc_synt 1.0 - 1.0 - 1.0 - 1.0 - 0.8 MGYG000002478_02180 0.2 adenylosuccinate synthase. succinoadenylic kinosynthetase. - GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01939:purA, ADSS; adenylosuccinate synthase [EC:6.3.4.4] 1.0 none 1.0 0 0 464038 316737 629577 236727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 639241 0 921101 707220 0 0 0 0 630826 0 0 0 218559 369492 251147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54752 0 0 0 0 0 0 0 0 172956 0 0 0 0 1178867 0 0 0 348844 940653 309972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213159 0 0 0 0 0 272647 0 0 0 0 0 0 0 0 0 0 0 0 102302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168808 0 0 0 0 0 0 0 0 0 71211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974520 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QFHNAYLK MGYG000002040_00997;MGYG000001300_02187;MGYG000003899_00641 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002040_00997 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 0 0 0 0 0 0 336277 0 0 104621 0 0 229697 0 0 0 144875 0 0 0 0 0 378276 0 0 0 0 0 0 0 0 884276 0 0 0 0 2045535 0 0 2009559 0 1577217 2625242 0 2816889 0 0 1813526 0 2245130 1893554 0 0 0 3443410 0 0 1199142 0 1250642 2814935 2095504 0 0 0 0 0 0 0 2543620 0 2459455 1835990 0 0 0 0 564590 0 1236765 1004289 0 199006 0 0 1258257 0 0 0 0 0 0 1186771 0 0 638492 0 0 1510353 0 0 0 0 0 0 0 0 1833299 0 0 0 0 275480 0 0 231693 0 0 388573 0 0 0 0 2169721 0 0 757667 0 0 0 1547308 0 0 188516 0 323976 2123224 1845894 0 0 0 0 0 0 0 1919899 0 421740 0 0 107157 0 0 0 0 639642 695726 0 500622 0 0 484990 0 995525 873919 0 0 0 670822 0 0 125087 0 480984 872217 553844 0 0 0 0 0 0 0 700358 0 666285 620297 0 +(Gln->pyro-Glu)QFHNAYLR MGYG000000022_02013 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_02013 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174768 0 0 0 0 371072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428369 0 0 0 0 495118 0 0 0 0 722655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1669241 0 0 0 0 1739378 0 0 0 0 1199084 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QFHNTFVK MGYG000004769_00464 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4H3YU@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_00464 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1423021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QFM(Oxidation)ANQR MGYG000004748_03679;MGYG000003363_02290;MGYG000001346_01518;MGYG000002478_00798;MGYG000002470_01229;MGYG000000196_03990;MGYG000002561_02176;MGYG000001337_03888;MGYG000001313_00073;MGYG000003221_01994;MGYG000001461_00405;MGYG000000243_01970;MGYG000002455_03900;MGYG000004185_01162;MGYG000000236_01786 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,2FM1W@200643|Bacteroidia,4AKIE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004748_03679 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QFMANQR MGYG000004748_03679;MGYG000003363_02290;MGYG000001346_01518;MGYG000002478_00798;MGYG000002470_01229;MGYG000000196_03990;MGYG000002561_02176;MGYG000001337_03888;MGYG000001313_00073;MGYG000003221_01994;MGYG000001461_00405;MGYG000000243_01970;MGYG000002455_03900;MGYG000004185_01162;MGYG000000236_01786 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0088@1|root,COG0088@2|Bacteria,4NEWZ@976|Bacteroidetes,2FM1W@200643|Bacteroidia,4AKIE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004748_03679 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 575083 0 0 0 796492 0 0 0 0 0 0 0 0 0 650814 0 0 0 0 0 0 0 0 0 0 0 0 575663 0 0 0 0 0 0 0 0 0 0 608529 0 0 0 1146107 0 0 0 0 0 0 0 0 0 500468 0 0 0 0 0 0 0 0 0 0 0 0 638953 0 0 0 0 0 0 0 0 0 0 280093 0 0 0 617973 0 0 0 0 0 0 0 0 0 167313 0 0 0 0 0 0 0 0 0 0 0 0 194119 0 0 0 0 0 0 0 0 0 0 236106 0 0 0 365941 0 0 0 0 0 0 0 0 0 420392 0 0 0 0 0 0 0 0 0 0 0 0 379315 0 0 0 0 0 0 0 0 0 0 359779 0 0 0 735885 0 0 0 0 0 0 0 0 0 189862 0 0 0 0 0 0 0 0 0 0 0 0 401281 0 0 0 0 +(Gln->pyro-Glu)QFNLM(Oxidation)FK MGYG000003366_01810;MGYG000001688_03818;MGYG000002523_01602;MGYG000000216_02240;MGYG000002298_01808;MGYG000002670_01474;MGYG000002937_00171;MGYG000001615_00144;MGYG000000002_01932;MGYG000001644_00341;MGYG000004196_01635;MGYG000003422_01231;MGYG000004839_00369;MGYG000000251_00298;MGYG000000031_02398;MGYG000002882_01752;MGYG000000348_01888;MGYG000003533_00387;MGYG000000378_00782;MGYG000000258_01693;MGYG000000371_00188;MGYG000004087_01279;MGYG000002116_00583;MGYG000002992_01229;MGYG000002794_00630;MGYG000000201_02682;MGYG000003256_02223;MGYG000003825_01449;MGYG000000416_00486;MGYG000001814_01722;MGYG000000354_00684;MGYG000000136_02286;MGYG000000119_01747;MGYG000004830_00903;MGYG000004487_00107;MGYG000003355_01218;MGYG000004475_00092;MGYG000000262_02744;MGYG000000223_03366;MGYG000001683_02052;MGYG000000142_02827;MGYG000000242_00227;MGYG000000501_00650;MGYG000000312_02403;MGYG000001500_00914;MGYG000000562_02504;MGYG000000462_01287;MGYG000002791_00657;MGYG000003533_00957;MGYG000001871_01158;MGYG000002057_00097;MGYG000004871_01776;MGYG000002279_02002;MGYG000002195_02035;MGYG000003694_01655;MGYG000004885_01325;MGYG000004735_00209;MGYG000004757_00072;MGYG000004271_01395;MGYG000000179_00115;MGYG000000249_01100;MGYG000000076_00068;MGYG000000193_01867;MGYG000001606_00310;MGYG000003498_00848;MGYG000002492_01703;MGYG000003535_01712;MGYG000000359_00712;MGYG000000133_02953;MGYG000003202_00086;MGYG000001711_01084;MGYG000003311_00453;MGYG000003427_01851;MGYG000002926_00944;MGYG000001913_01129;MGYG000000268_00696;MGYG000004733_01909;MGYG000003686_00223;MGYG000001319_00731;MGYG000000989_01980;MGYG000001764_00567;MGYG000000281_03413;MGYG000000212_00438;MGYG000000173_01055;MGYG000002149_01694;MGYG000002084_00804;MGYG000003147_00597;MGYG000002304_00986;MGYG000001733_00367;MGYG000000271_00389;MGYG000004525_01950;MGYG000001511_01429;MGYG000002720_01072;MGYG000000245_00871;MGYG000003486_02394;MGYG000002762_00453;MGYG000002212_01826;MGYG000001439_01577;MGYG000001622_02869;MGYG000000233_00373;MGYG000001781_01825;MGYG000003510_00241;MGYG000001651_00430;MGYG000003425_01035;MGYG000004869_04098;MGYG000002528_02207;MGYG000000198_00245;MGYG000000121_00703;MGYG000002517_01239;MGYG000004414_01227;MGYG000002715_00885;MGYG000001637_01168;MGYG000000252_02478 domain d__Bacteria 1.0 COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3WGTU@541000|Ruminococcaceae 0.2743362831858407 186801|Clostridia 0.8141592920353983 J 0.9911504424778761 Catalyzes the attachment of glycine to tRNA(Gly) 0.6460176991150443 glyQS 0.9734513274336283 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 0.8053097345132744 6.1.1.14 0.9911504424778761 ko:K01880 0.9911504424778761 ko00970,map00970 0.9911504424778761 M00359,M00360 0.9911504424778761 R03654 0.9911504424778761 RC00055,RC00523 0.9911504424778761 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 0.9911504424778761 - 1.0 - 1.0 - 0.9823008849557522 HGTP_anticodon,tRNA-synt_2b 0.9911504424778761 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003366_01810 0.008849557522123894 glycine--tRNA ligase. glycyl-tRNA synthetase. - ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). 0.9911504424778761 0.9911504424778761 0.9911504424778761 0.9911504424778761 Aminoacyl-tRNA biosynthesis 0.9911504424778761 K01880:GARS, glyS1; glycyl-tRNA synthetase [EC:6.1.1.14] 0.9911504424778761 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QFVEDDKILR MGYG000002492_01668 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 abc transporter atp-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K16786,ko:K16787 1.0 ko02010,map02010 1.0 M00582 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 1.0 - 1.0 - 1.0 ABC_tran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01668 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K16786:ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]|K16787:ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-] 1.0 none 1.0 0 0 3582480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284990 0 0 1653604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2194975 0 0 1839433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1071599 0 0 0 0 906810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1613234 0 0 0 0 0 0 0 818568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 904359 0 0 0 0 1588220 +(Gln->pyro-Glu)QFVVHR MGYG000003372_01707;MGYG000002494_00750;MGYG000002469_00977;MGYG000001292_01716;MGYG000002477_03920;MGYG000003683_00691 domain d__Bacteria 1.0 COG0823@1|root,COG0823@2|Bacteria,1MV09@1224|Proteobacteria,1RMCY@1236|Gammaproteobacteria,3WXKH@544|Citrobacter 0.5 1236|Gammaproteobacteria 0.5 U 0.5 Involved in the TonB-independent uptake of proteins 0.5 tolB 0.5 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 0.5 - 0.5 ko:K03641 0.5 - 0.5 - 0.5 - 0.5 - 0.5 ko00000,ko02000 0.5 2.C.1.2 0.5 - 1.0 - 1.0 PD40,TolB_N 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003372_01707 0.16666666666666666 - - - - 0.5 0.5 0.5 0.5 - 0.5 K03641:tolB; TolB protein 0.5 none 1.0 0 0 430387 0 0 0 0 0 0 0 0 0 846471 0 0 0 0 234029 0 0 0 0 112500 0 0 0 0 282807 0 0 0 0 0 0 0 0 0 264315 0 0 948873 0 0 0 0 0 0 0 0 0 2287553 0 0 0 0 2019190 0 0 0 0 785142 0 0 0 0 1893205 0 0 1150830 0 697477 0 0 0 0 1389553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143337 0 0 0 0 548492 0 0 0 0 148631 0 0 0 0 202274 0 0 234205 0 0 0 0 0 0 0 0 0 129582 0 0 0 0 124959 0 0 0 0 0 0 0 0 0 0 0 0 206104 0 200222 0 0 0 0 165721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151452 0 0 0 0 0 +(Gln->pyro-Glu)QFYGSGFSDETYENAKK MGYG000001300_00301;MGYG000002223_00312 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Radical SAM domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,Radical_SAM,SPASM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00301 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507239 573251 615723 538587 0 555499 720138 0 662537 0 0 461654 0 0 0 0 711221 0 838803 555280 0 356543 0 558421 0 533997 683839 0 0 0 700720 0 489352 0 0 0 568139 452039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444527 0 0 502001 403884 0 0 0 0 0 0 0 0 0 347236 0 0 0 0 412723 0 0 0 0 0 0 0 0 501445 0 360833 0 0 0 0 288560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGADIIAVIR MGYG000002794_00763;MGYG000002926_00664;MGYG000002882_00085;MGYG000002720_00861;MGYG000002931_00001;MGYG000002143_01959;MGYG000001733_00672;MGYG000004196_01673;MGYG000004487_00297;MGYG000002086_01355 domain d__Bacteria 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 0.9 186801|Clostridia 0.9 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 0.9 kamD 0.9 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_00763 0.1 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K01844:kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 108327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGADVIAVIR MGYG000000099_02239;MGYG000003801_01081 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,267NE@186813|unclassified Clostridiales 0.5 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 0.5 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_02239 0.5 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K01844:kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3] 1.0 none 1.0 73823 0 0 0 0 0 0 220385 110927 0 0 0 0 0 0 0 0 0 0 192542 0 0 0 0 0 181473 120499 0 0 0 0 0 0 100396 0 0 208138 0 601089 0 0 0 0 0 1432054 456960 814829 0 0 0 0 0 0 0 0 0 0 711307 0 0 0 0 0 624870 610539 0 0 0 0 0 0 585041 0 749521 502450 0 1760482 0 0 0 0 0 439513 1336895 286226 0 0 0 0 0 0 0 0 0 0 1422258 0 0 0 0 0 818454 1366830 0 0 0 0 0 0 1462204 0 451497 933571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102161 105231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGANLQESNDKMFER MGYG000002478_00270;MGYG000000243_02147;MGYG000002171_01599 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,2FM2T@200643|Bacteroidia,4AKYC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 maeB 1.0 - 1.0 1.1.1.38,1.1.1.40 1.0 ko:K00027,ko:K00029 1.0 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 1.0 M00169,M00172 1.0 R00214,R00216 1.0 RC00105 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,PTA_PTB,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00270 0.3333333333333333 malate dehydrogenase (oxaloacetate-decarboxylating). | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. | The enzyme catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate, cf. EC 1.1.1.38 and EC 1.1.1.39. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. | (1) (S)-malate + NADP(+) = CO2 + NADPH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Two-component system 1.0 K00027:ME2, sfcA, maeA; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]|K00029:maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] 1.0 none 1.0 0 0 596536 0 700792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 650866 0 0 0 0 518433 0 0 395914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGASKDEANDIK MGYG000000233_00504;MGYG000000255_02155 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_00504 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 504045 0 0 453495 0 371840 401970 725132 572776 440130 0 0 0 681790 0 0 0 0 471755 593103 0 684487 0 517463 0 441064 520635 0 658845 514930 0 351998 0 1057351 0 654085 420002 0 2109860 0 1984297 2871905 0 2199462 2086360 2815016 2411587 2137863 0 0 0 2320638 0 0 0 0 2015460 1470692 0 1558367 0 1600941 0 1716487 1743562 0 1700381 2126593 0 1770890 1850806 1867201 0 1588215 1893126 1588424 529459 0 0 223998 0 0 0 201410 399663 603395 0 0 0 393391 0 0 0 0 0 167212 0 0 0 0 0 627849 712878 0 449725 526151 0 225614 0 716953 0 675512 385982 0 1009026 0 1110791 962676 0 919504 1515701 1473655 1112865 1265542 0 0 0 1078784 0 0 0 0 1216360 874117 0 1330152 0 993388 0 1310201 1225190 0 1105431 863489 0 944213 1012240 1463186 0 1145337 1052646 950040 0 0 0 165019 0 195702 143379 283892 0 0 0 0 0 0 0 0 0 0 451725 0 0 467584 0 0 0 172154 0 0 210685 0 0 257995 0 687245 0 0 0 339522 +(Gln->pyro-Glu)QGASKDEANDIKTK MGYG000000233_00504;MGYG000000255_02155 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_00504 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 222438 0 0 427590 0 0 0 0 0 0 0 0 226878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427922 0 0 509196 0 0 507224 0 0 0 0 0 645089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203774 0 0 325016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254841 0 0 612670 0 0 400235 0 0 0 0 0 286626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGASKEEANDIK MGYG000001199_02683;MGYG000000242_00771 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001199_02683 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133701 0 0 0 0 176284 0 0 0 0 166158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217452 0 0 0 0 569588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1864513 0 0 0 0 2337755 0 0 0 0 1849815 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGDDIEILNPEWHIATLGEGAK MGYG000001300_02186;MGYG000001255_02105 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WGUM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 - 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02186 0.5 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGDSDTVSLK MGYG000000242_00772 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000242_00772 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366708 0 0 0 0 277802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516224 0 0 0 0 446817 0 0 0 0 308711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2824348 0 0 0 0 2641513 0 0 0 0 2488666 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGEAATEEASERA MGYG000001490_00318;MGYG000003452_00078;MGYG000000756_00970;MGYG000003683_01140;MGYG000002395_00348 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001490_00318 0.2 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]|K15515:sauS; sulfoacetaldehyde dehydrogenase [EC:1.2.1.81] 1.0 none 1.0 0 0 590072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386610 0 0 0 0 356648 0 0 1054890 0 0 461706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209291 0 910573 0 0 0 0 0 0 1257185 0 946275 0 0 0 0 1519494 0 0 531547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1138513 0 0 0 0 346289 0 0 0 0 0 408554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 876601 0 705555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGEEFPQDPKEQLIGAVK MGYG000000084_02524;MGYG000004866_01031;MGYG000001157_01952 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000084_02524 0.3333333333333333 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723686 0 0 0 0 0 0 0 0 0 189440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 589019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGEGVAATIVDLGNR MGYG000002455_02701 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,2FMIU@200643|Bacteroidia,4APG1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the conversion of L-arabinose to L-ribulose 1.0 araA 1.0 - 1.0 5.3.1.4 1.0 ko:K01804 1.0 ko00040,ko01100,map00040,map01100 1.0 - 1.0 R01761 1.0 RC00516 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Arabinose_Iso_C,Arabinose_Isome 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_02701 1.0 L-arabinose isomerase. L-arabinose ketol-isomerase. Requires a divalent metal ion (the enzyme from the bacterium Escherichia coli prefers Mn(2+)).-!-The enzyme binds beta-L-arabinopyranose and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene-diol mechanism.-!-The enzyme can also convert alpha-D-galactose to D-tagatose with lower efficiency. beta-L-arabinopyranose = L-ribulose. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Metabolic pathways 1.0 K01804:araA; L-arabinose isomerase [EC:5.3.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 628380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456666 0 0 0 0 336720 0 0 0 0 166813 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGELDDKQLEDGLTEKK MGYG000000224_00341;MGYG000000105_02189;MGYG000003681_00297;MGYG000001313_01991 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,2FN0C@200643|Bacteroidia,4AKKG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG19144 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000224_00341 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 419515 0 0 397549 0 0 0 0 0 691214 0 546210 0 479043 0 0 417385 245374 0 0 0 0 218018 0 0 456199 0 0 0 0 0 0 0 0 492505 0 494115 0 489814 0 0 526392 0 0 0 0 0 681160 0 725763 0 541763 0 0 567207 977943 0 0 0 0 847556 0 0 485164 0 1181261 0 0 0 0 0 0 600353 0 572886 0 294075 0 0 200970 0 0 0 0 0 335946 0 304195 0 325358 0 0 434177 0 0 0 0 0 0 0 0 230306 0 0 0 0 0 0 0 0 446106 0 178329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGENRPSGGHEIVLKPIEGVR MGYG000000255_01680 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,27UZQ@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01680 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 323453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165759 0 0 0 0 0 0 0 0 0 0 0 0 407255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386684 0 0 0 0 0 0 0 0 0 0 373807 0 227436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271572 0 0 0 0 0 0 0 0 0 0 0 0 113700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124863 0 0 0 0 0 0 0 0 0 0 150717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGEVITAEVVR MGYG000003170_00225;MGYG000001410_02390 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella 1.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,4PQ3M@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003170_00225 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572928 0 0 0 +(Gln->pyro-Glu)QGFEVYTTAEAAK MGYG000000245_00071;MGYG000000271_00298;MGYG000004271_02052 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 1.0 186801|Clostridia 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000245_00071 0.3333333333333333 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGFYNKDIITESIKR MGYG000003697_02156 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0524@1|root,COG0524@2|Bacteria,4NGFK@976|Bacteroidetes,2FN72@200643|Bacteroidia,22WT2@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 pfkB family 1.0 ydjH_1 1.0 - 1.0 2.7.1.4 1.0 ko:K00847 1.0 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 1.0 - 1.0 R00760,R00867,R03920 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_02156 1.0 fructokinase. D-fructokinase. - ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K00847:E2.7.1.4, scrK; fructokinase [EC:2.7.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769359 0 0 822797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511952 0 417077 0 0 0 0 0 0 0 0 676908 0 0 0 0 419149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGGEVVGNHTR MGYG000002517_01765 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia 1.0 186801|Clostridia 1.0 L 1.0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage 1.0 recA 1.0 - 1.0 - 1.0 ko:K03553 1.0 ko03440,map03440 1.0 M00729 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03400 1.0 - 1.0 - 1.0 - 1.0 RecA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01765 1.0 - - - - 1.0 1.0 1.0 1.0 Homologous recombination 1.0 K03553:recA; recombination protein RecA 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGGIGFIHK MGYG000002485_02170;MGYG000004893_01198;MGYG000004828_01108;MGYG000001327_01268 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,378I3@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_02170 0.25 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 0 297105 0 0 0 0 0 0 598792 0 0 0 0 0 216813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 441619 0 471013 0 0 467177 0 0 1123716 0 0 0 0 0 0 1078369 0 0 0 0 0 1135175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 940250 0 772377 0 0 883869 0 0 150782 0 0 0 0 0 0 363370 0 0 0 0 0 269770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311732 0 0 562299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 622235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585842 +(Gln->pyro-Glu)QGGIGIIHK MGYG000004847_02037;MGYG000000271_00603;MGYG000002901_00218;MGYG000003149_00433;MGYG000000087_02531;MGYG000000213_01314;MGYG000000562_02421;MGYG000000171_02641;MGYG000001367_02921;MGYG000004879_00512;MGYG000004271_01872;MGYG000002517_01047;MGYG000003783_01872;MGYG000001645_00506;MGYG000002492_02315;MGYG000000489_00932;MGYG000003486_02497;MGYG000000080_01161;MGYG000002528_02466;MGYG000000204_01913;MGYG000000212_00040;MGYG000001319_00739;MGYG000000136_01100;MGYG000004250_01264;MGYG000004735_02781;MGYG000002966_01598;MGYG000000146_01483;MGYG000002992_01076;MGYG000000233_01272;MGYG000001193_00608;MGYG000000164_00891;MGYG000000205_01225;MGYG000001315_00701;MGYG000000028_00786;MGYG000001186_00833;MGYG000000127_02910;MGYG000000206_01855;MGYG000000187_01407;MGYG000000133_00306;MGYG000000142_02314;MGYG000004740_01385;MGYG000003984_01817;MGYG000000356_01714;MGYG000002670_00089;MGYG000000263_02824;MGYG000002247_00883;MGYG000004642_00172;MGYG000003694_03060;MGYG000000193_00312;MGYG000001338_00214;MGYG000004869_03402;MGYG000000301_00957;MGYG000004884_01768;MGYG000000989_02246;MGYG000000252_03031;MGYG000001748_02097;MGYG000000262_01414;MGYG000001314_02149;MGYG000003782.1_00452;MGYG000004785_01919;MGYG000002279_00396;MGYG000000077_00487;MGYG000001623_01024;MGYG000000251_01328;MGYG000002298_01715;MGYG000004285_01802;MGYG000001637_01052;MGYG000002835_00811;MGYG000000002_02500;MGYG000001219_01350;MGYG000003366_01162;MGYG000001571_02994;MGYG000003695_02134;MGYG000000092_00381;MGYG000002985_01150;MGYG000004087_02343 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia 0.2236842105263158 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004847_02037 0.013157894736842105 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 2354011 2793765 2373496 1641613 3086858 3487239 1315804 3207496 1936679 2688630 2538011 2952400 3657663 2965391 2747130 3117380 3085105 2852382 2196633 2663577 3142663 3503856 2111843 1479558 2712302 1933601 2398627 2813588 2348706 2607921 1581039 3129233 2243973 2355399 2587041 2086207 2035847 2651530 1935103 2848634 1719858 1543140 1676971 1300688 1525492 2091387 2086048 1732423 1361265 1379121 1660233 1191243 1297272 1258882 1541997 2198146 1546344 1508735 1218233 985276 1294167 1642043 1665710 1541150 1821422 2378402 2283609 1536911 3115447 1738622 1913653 2354310 2633593 2085736 1846132 2415449 3848944 6823784 3896597 4110785 1949946 3097082 2326064 3859613 2950933 3281389 2883566 2618110 3310058 3668202 3880292 3629639 3661575 1861430 4039793 3669915 3202191 0 2300999 2793549 4773181 3576364 4467507 3004935 3663661 4000317 2542309 6015991 5154041 4777307 4299816 2472929 3331288 3490374 3270636 0 1523750 3677503 3613528 3002410 3047463 3990864 3626818 3884848 0 3283667 2806076 4293938 3598465 3392213 3758971 0 3363519 3657257 2620884 1758864 575924 1608547 3478602 3358540 4166438 183133 5034211 3781020 3775231 3994388 2468360 1956357 3752591 2927935 3386171 594756 3239069 4048926 4978246 4162388 1789030 3069053 4584077 3221794 3030462 4686013 3170069 4114659 2072122 4204062 4025018 2768451 3354198 1437978 3268103 1869646 4080087 4308902 2371089 2652000 3568757 2575654 3368659 2559366 4233660 1708816 3706767 4919636 6071032 4035456 3102825 3632353 3218146 4083149 +(Gln->pyro-Glu)QGGITLMMDR MGYG000002515_03615;MGYG000002494_01532;MGYG000002534_04857 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1MV7M@1224|Proteobacteria,1RNA8@1236|Gammaproteobacteria,3WVBR@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iEC042_1314.EC042_4152,iECABU_c1320.ECABU_c42560,iECED1_1282.ECED1_4460,iECO103_1326.ECO103_4390,iECO111_1330.ECO111_4600,iECO26_1355.ECO26_4812,iECP_1309.ECP_3967,iECSE_1348.ECSE_4057,iECUMN_1333.ECUMN_4300,iEcE24377_1341.EcE24377A_4285,iEcSMS35_1347.EcSMS35_4140,iJN746.PP_4678,iLF82_1304.LF82_1103 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_03615 0.3333333333333333 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319843 0 296905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 96646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGGLGIIHK MGYG000001412_04889;MGYG000000271_00603;MGYG000001338_00214;MGYG000002528_02466;MGYG000001193_00608;MGYG000000164_00891;MGYG000002835_00811;MGYG000000262_01414;MGYG000002279_00396 domain d__Bacteria 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,267WW@186813|unclassified Clostridiales 0.2222222222222222 186801|Clostridia 0.8888888888888888 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 0.8888888888888888 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001412_04889 0.1111111111111111 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4863385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGGLQFIDEVK MGYG000001364_02756;MGYG000001835_01810;MGYG000002478_00801;MGYG000004763_00924;MGYG000003693_00191;MGYG000000243_01973;MGYG000001783_02408;MGYG000001306_02658 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia,4AKVK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000001364_02756 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 801066 0 0 0 0 954380 0 0 0 0 881008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGGSNRETFTVR MGYG000004719_02005;MGYG000002517_01927;MGYG000002212_02160;MGYG000004271_01601;MGYG000000271_00796 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia 0.8 186801|Clostridia 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 - 1.0 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004719_02005 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02884:RP-L19, MRPL19, rplS; large subunit ribosomal protein L19 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGGVRESLEDKTMNLAK MGYG000002478_00968;MGYG000004797_01273 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00968 0.5 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01818:fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGGVRESLEEK MGYG000001783_00644;MGYG000000243_02351 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001783_00644 0.5 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01818:fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGHDVKGPTAAGNSVAK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 0.5 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 1048136 3012378 1242880 450331 3857600 2352282 120811 1817552 443817 1988358 1298381 1534742 3474616 1042135 1583170 4089853 1240142 0 1245941 1507067 945885 3503353 0 514592 1724538 789290 688694 0 581254 1121550 792146 2238570 753316 1038400 980724 368086 583753 1239490 2647329 2722791 528109 1157254 828566 1433811 3435838 1246815 1651791 951122 611435 565947 1200505 737456 932769 637155 875727 0 1425443 1911382 1158658 846329 0 2368726 1142754 1619778 1839869 0 2929851 1047636 1955213 1112980 642182 2166599 1908061 2358819 1365609 754974 5028162 10885980 1540305 6639471 884969 5814097 1086051 6356866 1263453 4579819 1923452 2837305 4006930 3369390 5340693 4261309 3747388 0 6835743 4856076 3381408 8329198 0 2984427 6039179 4150647 7206797 0 805882 3748773 1728629 5756074 3446313 7380607 2043283 1632157 3585816 1329733 2283833 2399083 1609351 2931797 1915029 3460896 3327410 2335519 2381260 4927846 1918278 1529164 3506828 2544117 2394527 4108528 3391638 0 1817479 3184939 1575435 2286189 0 2011498 2449744 966511 2864650 0 1901264 2533874 334308 1725552 1876890 1818710 2428062 1985760 1398039 1362728 2036041 3268825 5650694 2651269 5835598 3502890 1196026 1688696 2570726 3480658 5703270 2605002 6620983 1843763 1841325 3854461 2555647 0 2751462 2009720 1365725 2854620 0 1997670 2066879 2808784 1805645 0 608039 2095943 5483511 4774754 5530737 2548670 2722913 2784960 2963824 4845140 +(Gln->pyro-Glu)QGHDVKGPTAAGNSVAKLDQLNISN(Deamidated)GTLYNQK MGYG000000262_02730 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02730 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 963145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGHRQPYTK MGYG000002720_00243;MGYG000001658_02153;MGYG000002057_00937;MGYG000003686_02150;MGYG000001502_03046;MGYG000003819_01744 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,2N7IB@216572|Oscillospiraceae 0.6666666666666666 186801|Clostridia 0.8333333333333334 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 - 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_00243 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02888:RP-L21, MRPL21, rplU; large subunit ribosomal protein L21 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGIAKLPEGNDYEQAAK MGYG000002293_00078;MGYG000001770_00051 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the transketolase family 1.0 tkt 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00078 0.5 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1576901 0 0 0 0 2386996 0 0 0 0 2129499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGIAVDKDYYYVSDTK MGYG000003681_01837 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG3391@1|root,COG3391@2|Bacteria,4NJJN@976|Bacteroidetes,2FNI0@200643|Bacteroidia,22Z3Y@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 amine dehydrogenase activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_01837 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 529502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448365 0 0 582393 0 0 0 0 612548 0 0 0 0 0 0 0 0 0 924852 0 0 0 0 0 0 482299 602534 0 0 0 0 0 0 0 0 0 510259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395663 468855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGIGLVGYGQRDPVVEYK MGYG000000212_01327;MGYG000000301_01158;MGYG000000133_00962 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3XYPH@572511|Blautia 1.0 186801|Clostridia 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane 1.0 secA 1.0 - 1.0 - 1.0 ko:K03070 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 1.0 - 1.0 - 1.0 Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW 1.0 - 1.0 - 1.0 GT41 1.0 - 1.0 MGYG000000212_01327 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03070:secA; preprotein translocase subunit SecA [EC:7.4.2.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169438 0 0 0 0 195276 0 0 98367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228191 0 0 0 0 220395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 536634 0 0 0 0 272604 +(Gln->pyro-Glu)QGIHPNYVDC(Carbamidomethyl)TITC(Carbamidomethyl)AC(Carbamidomethyl)GNVIK MGYG000001300_00389;MGYG000003166_00009;MGYG000002274_00606;MGYG000002651_01024;MGYG000002040_00344;MGYG000000022_01287 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3WKI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds the 23S rRNA 1.0 rpmE 1.0 - 1.0 - 1.0 ko:K02909 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L31 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00389 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02909:RP-L31, rpmE; large subunit ribosomal protein L31 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 483244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGIHPNYYQAK MGYG000000205_01476;MGYG000000233_00887;MGYG000000255_02664 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,220Y9@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 50S ribosomal protein L31 1.0 rpmE 1.0 - 1.0 - 1.0 ko:K02909 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L31 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_01476 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02909:RP-L31, rpmE; large subunit ribosomal protein L31 1.0 none 1.0 0 0 0 0 318934 0 0 0 0 426951 0 0 0 512305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395960 0 0 372431 0 676962 0 0 0 493569 0 0 0 0 902635 1068073 0 0 495653 0 0 768615 0 0 0 0 0 0 0 0 374904 596671 0 0 0 0 0 0 823869 0 0 365786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGILDPDTLTKEER MGYG000000198_04022 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,21XTX@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 FAD dependent oxidoreductase 1.0 lhgO 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04022 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 1079831 0 335921 863431 651654 0 392075 811018 532882 944466 0 0 679947 1030185 714162 390045 576518 0 839930 1308686 737948 0 0 0 0 949814 888956 0 757957 892219 0 0 0 451309 919864 874518 734131 280129 250855 0 0 356736 0 0 418191 0 403793 420263 0 0 483953 382795 0 0 0 0 301969 376674 426425 0 0 0 0 343249 640438 0 717709 0 0 0 0 0 404309 0 424310 0 1145454 0 689649 1277466 0 0 761365 877711 1034479 795139 0 0 703144 1031421 1161400 745830 629535 0 1092188 1111052 1015222 0 0 0 0 860318 1186519 0 1078301 1003052 0 0 491377 1220038 575198 688435 823606 568254 192285 0 0 0 0 0 456026 0 0 0 0 0 0 0 0 217267 0 0 0 0 0 0 0 0 0 0 0 0 0 250938 0 0 0 0 0 0 0 0 0 0 184407 0 0 0 365835 206146 318598 322596 0 0 0 0 0 0 380157 0 0 0 441090 0 0 0 0 170995 0 0 0 363742 0 0 0 0 0 298547 0 0 +(Gln->pyro-Glu)QGIQWMIADMATK MGYG000004736_01082 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Evtepia|s__Evtepia sp004554585|m__MGYG000004736 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WI1F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004736_01082 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGKFDFC(Carbamidomethyl)R MGYG000000133_00227 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,36EHU@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 Family 5 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00227 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 205175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135516 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 834288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1147215 0 0 0 0 700127 +(Gln->pyro-Glu)QGKFPGLR MGYG000002438_02078 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,2FN0C@200643|Bacteroidia,22YIM@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG19144 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02078 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181288 0 0 0 0 0 0 0 0 0 0 0 0 212950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736235 0 412887 0 0 0 0 0 0 0 0 0 0 168138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385574 0 0 0 0 0 0 0 0 0 0 0 0 215836 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 792248 0 732586 0 0 0 0 0 0 0 0 0 0 1738609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2972073 0 2257930 0 0 0 0 0 0 +(Gln->pyro-Glu)QGKIDFKVDK MGYG000000196_03979;MGYG000001370_01685;MGYG000000243_01983;MGYG000001835_01818;MGYG000002478_00809;MGYG000001345_04689 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,2FNKI@200643|Bacteroidia,4ANG1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_03979 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGKPLEDLSLADLQK MGYG000002494_01893 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0165@1|root,COG0165@2|Bacteria,1MUTU@1224|Proteobacteria,1RMA3@1236|Gammaproteobacteria,3XMS6@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 argininosuccinate lyase 1.0 argH 1.0 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.3.1.1,4.3.2.1 1.0 ko:K01755,ko:K14681 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map01100,map01110,map01130,map01210,map01230 1.0 M00028,M00029,M00844,M00845 1.0 R00259,R01086 1.0 RC00004,RC00064,RC00445,RC00447 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ASL_C2,Acetyltransf_1,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01893 1.0 amino-acid N-acetyltransferase. | argininosuccinate lyase. N-acetylglutamate synthase. | omega-N-(L-arginino)succinate arginine-lyase. Also acts with L-aspartate and, more slowly, with some other amino acids. acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate. | 2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K01755:argH, ASL; argininosuccinate lyase [EC:4.3.2.1]|K14681:argHA; argininosuccinate lyase / amino-acid N-acetyltransferase [EC:4.3.2.1 2.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692773 465747 0 0 915932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1452265 0 841564 0 0 0 0 0 0 0 0 474034 0 0 0 0 345094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGKPQVNYK MGYG000000196_03987;MGYG000001659_00198;MGYG000001599_01853;MGYG000002293_00507 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia,4AKVK@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000000196_03987 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520235 0 0 0 292567 0 0 0 0 323645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 991457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 735993 0 0 0 571577 0 0 0 0 956304 0 0 1666447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1223919 0 0 0 1617881 0 0 0 0 2051642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGKYDDAVNAYTK MGYG000000013_00602 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp902362375|m__MGYG000000013 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,4ANQH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_00602 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 758814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3167185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGLDELIDK MGYG000000179_02173 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,21XTX@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 FAD dependent oxidoreductase 1.0 lhgO 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02173 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 145982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79190 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 614056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 667220 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGLDFVR MGYG000000028_00488 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus_A|m__MGYG000000028 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD,NAD_binding_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000028_00488 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 734602 0 236077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGLDHVC(Carbamidomethyl)SAAR MGYG000002517_00257 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00257 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 234739 464287 0 0 301528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5330038 0 0 5554411 2417426 417700 4042779 7745857 10447838 1945957 1634185 2707444 0 7984101 6836794 0 3616313 0 5950350 7875172 3321516 0 0 769029 7553920 9334462 6391525 0 0 3444581 0 0 0 5549636 6741260 6196456 10220210 1501201 5775489 0 5007572 0 3433033 4001522 7179027 5627694 7565352 7667044 5175321 4649669 0 8456655 8028817 4016505 6161418 0 4873320 4328752 5645215 3235362 0 3679524 10908099 10989126 5692478 0 0 4094624 4605037 0 5057469 8226158 6637948 10809641 8655897 6060144 +(Gln->pyro-Glu)QGM(Oxidation)LAGLDKLADTVK MGYG000003683_00853;MGYG000000756_00212;MGYG000002395_00609;MGYG000002459_00653 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CZJK@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003683_00853 0.25 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGMIDEKTALER MGYG000004797_01193;MGYG000002478_03849 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000004797_01193 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGNALGWATAGGSGFR MGYG000002515_03180;MGYG000002385_00373;MGYG000001708_01489;MGYG000002534_00415;MGYG000001466_00767;MGYG000002415_02008;MGYG000002476_04062;MGYG000002525_03273;MGYG000002514_02441;MGYG000002536_00956;MGYG000002323_00409;MGYG000003386_02373;MGYG000002513_02354;MGYG000002506_02938;MGYG000002477_00164 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,3WY9K@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_03180 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 1.0 none 1.0 153720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242673 0 0 0 0 516202 0 0 0 0 1173111 0 0 443786 992637 0 0 0 781596 0 0 655444 0 768886 0 0 1280157 0 776050 981335 600712 0 0 872749 0 0 0 0 451866 0 0 407770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 420547 0 0 0 0 0 0 0 0 0 324284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGNLLELAVEAAK MGYG000003279_00971;MGYG000004658_00971;MGYG000000003_01875 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,22U75@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 B12 binding domain 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003279_00971 0.3333333333333333 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 6427406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 888992 0 0 6082341 0 0 0 0 0 0 7663356 0 0 10275611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3874 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4197654 0 0 0 0 0 0 0 3616459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1517513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGNQEAAPAEDAANA MGYG000002272_01435;MGYG000001300_00246;MGYG000002223_00595;MGYG000002274_00630;MGYG000002545_00160 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002272_01435 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGNTELQQK MGYG000002506_00187;MGYG000003390_02380;MGYG000003360_01604;MGYG000003372_02171;MGYG000002494_00886;MGYG000002323_01448;MGYG000003883_00530 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0834@1|root,COG0834@2|Bacteria,1MXIA@1224|Proteobacteria,1RPXK@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 ET 1.0 belongs to the bacterial solute-binding protein 3 family 1.0 artI 1.0 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 1.0 - 1.0 ko:K09996,ko:K09997,ko:K10014 1.0 ko02010,map02010 1.0 M00226,M00229 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.3.1,3.A.1.3.3 1.0 - 1.0 iLF82_1304.LF82_0153,iNRG857_1313.NRG857_03895,iPC815.YPO1351 1.0 SBP_bac_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00187 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K09996:artJ; arginine transport system substrate-binding protein|K09997:artI; arginine transport system substrate-binding protein|K10014:hisJ; histidine transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 144780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 918982 0 232431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGQIWIR MGYG000002281_02268;MGYG000002549_02918;MGYG000001345_04706;MGYG000000196_03996;MGYG000003693_00200;MGYG000004763_00933;MGYG000000243_01964;MGYG000001346_01512;MGYG000001313_00067;MGYG000001378_05020;MGYG000002560_00243;MGYG000001599_01844;MGYG000002561_02182;MGYG000000105_02011;MGYG000002455_03906;MGYG000000054_03865;MGYG000000098_01995;MGYG000003256_00317;MGYG000002478_00792;MGYG000002933_02454;MGYG000001370_01702;MGYG000003312_02984;MGYG000001364_02747;MGYG000000013_02229 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,2FRZE@200643|Bacteroidia,4AKTM@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs 1.0 rplP 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02878 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_02268 0.041666666666666664 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02878:RP-L16, MRPL16, rplP; large subunit ribosomal protein L16 1.0 none 1.0 341935 0 405846 315482 0 248727 374068 479609 0 538926 571258 304561 469480 336165 341210 308896 269682 200000 589180 0 544887 392878 350099 522980 345221 501822 0 277881 0 0 0 0 345969 546039 0 0 407657 324507 356806 0 517176 504118 0 344718 498412 676211 0 565564 679844 562964 155095 472835 486392 483508 377870 457970 463023 0 299641 470823 585775 357147 347246 498522 0 381936 0 0 0 363172 386683 269395 0 0 454994 340186 97581 0 334278 490046 0 288749 326305 265580 0 244741 564312 470343 367626 327877 315848 342760 80960 132352 373606 0 281622 261888 111187 494052 298533 215740 0 386420 0 0 0 89203 120721 353809 0 0 106186 375737 90378 0 170060 202166 0 191908 213115 277639 0 191346 353492 255447 387407 84801 293004 308599 188026 119954 256921 0 95772 184976 148969 82407 0 107058 0 0 0 0 0 351156 412268 298230 0 0 330347 264645 86962 0 190426 85493 0 362583 243737 255953 0 320196 556865 210597 336294 87877 87494 296328 237288 458675 315143 0 71899 154899 83048 212932 183254 194103 0 574367 0 0 0 191355 197457 405368 0 0 253888 253650 +(Gln->pyro-Glu)QGQLLMTR MGYG000000077_02469;MGYG000000262_02236 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,25UTQ@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 etfA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02469 0.5 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107852 0 0 143380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298798 0 0 0 0 0 0 0 0 0 0 0 0 384626 0 0 900109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 590017 0 0 0 0 0 792434 0 0 0 0 588750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGQLWIR MGYG000002291_02248;MGYG000002549_02918;MGYG000001345_04706;MGYG000000196_03996;MGYG000004763_00933;MGYG000000243_01964;MGYG000001346_01512;MGYG000001433_02283;MGYG000001378_05020;MGYG000001599_01844;MGYG000004185_01156;MGYG000000105_02011;MGYG000002455_03906;MGYG000000098_01995;MGYG000002478_00792;MGYG000000013_02229 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0197@1|root,COG0197@2|Bacteria,4NM87@976|Bacteroidetes,2FRZE@200643|Bacteroidia,4AKTM@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs 1.0 rplP 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02878 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002291_02248 0.0625 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02878:RP-L16, MRPL16, rplP; large subunit ribosomal protein L16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 508634 0 0 0 0 273676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286469 0 0 0 0 97996 0 0 0 0 0 0 +(Gln->pyro-Glu)QGQVWIR MGYG000004629_00397;MGYG000001056_01156;MGYG000002603_01760;MGYG000001975_01109;MGYG000003697_01461;MGYG000003374_01448;MGYG000002108_01886;MGYG000002293_00498;MGYG000001770_00602;MGYG000003287_00278;MGYG000002080_00548;MGYG000002834_00447;MGYG000000215_01907;MGYG000003353_02087 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,2FMYX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 1.0 rpsC 1.0 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02982 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004629_00397 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02982:RP-S3, rpsC; small subunit ribosomal protein S3 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106685 0 0 0 0 126167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 873658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 780838 0 0 0 0 1034837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGSIRAPQWTGGGVVFAPVPR MGYG000002298_00329;MGYG000001338_02806 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_00329 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGSTRAPQWTHGGVVFAPVPR MGYG000004271_00017;MGYG000002517_02872;MGYG000000271_01062 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00017 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGTGIKPGDLK MGYG000003697_01173 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AWE5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01173 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 834742 0 0 0 0 638006 0 0 0 0 602173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371112 0 0 0 0 256842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2290963 0 0 0 0 2481639 0 0 0 0 2514286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775408 0 0 0 0 500644 0 0 0 0 612041 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGTQSALTR MGYG000004487_01021;MGYG000002964_01300;MGYG000004246_00716;MGYG000001476_03271;MGYG000002707_00964;MGYG000001193_00545;MGYG000003819_01159;MGYG000001675_00231;MGYG000004784_00635;MGYG000000099_02400;MGYG000002143_00708;MGYG000001616_02450;MGYG000001733_00032;MGYG000003686_01083;MGYG000000743_00443;MGYG000002159_00259;MGYG000003589_01463;MGYG000001576_02390;MGYG000002882_01831;MGYG000002057_00234;MGYG000004736_00666;MGYG000004124_01019;MGYG000000258_00282;MGYG000000036_00624;MGYG000002934_00474;MGYG000002115_00710;MGYG000004196_00637;MGYG000000392_01460;MGYG000002926_00535;MGYG000002944_01721;MGYG000001500_00883;MGYG000003581_01700;MGYG000001781_02370;MGYG000002116_01180;MGYG000004201_00826;MGYG000004727_00006;MGYG000004831_00879;MGYG000002229_01222;MGYG000002523_01978;MGYG000002794_00540;MGYG000002953_00592;MGYG000004482_00988;MGYG000003409_02387;MGYG000002857_00040;MGYG000000328_00214;MGYG000003453_00779;MGYG000003770_00994;MGYG000002727_02380;MGYG000004276_01040;MGYG000001502_00411;MGYG000001824_00247 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,2N6EK@216572|Oscillospiraceae 0.49019607843137253 186801|Clostridia 0.9607843137254902 J 1.0 Forms part of the polypeptide exit tunnel 0.5098039215686274 rplD 1.0 - 0.9607843137254902 - 1.0 ko:K02926 0.9607843137254902 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 0.9607843137254902 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004487_01021 0.0196078431372549 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 0.9607843137254902 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGVDGDHVDYTNQSHPV MGYG000001300_00241 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00241 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 734251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGVGTGSC(Carbamidomethyl)NLIFTK MGYG000000140_01408;MGYG000000076_03383;MGYG000002024_01702 domain d__Bacteria 1.0 2FJFS@1|root,34B5D@2|Bacteria,1W0D9@1239|Firmicutes,24WID@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000140_01408 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 430917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1355260 0 0 0 0 2179691 0 0 0 0 1576905 3110605 0 0 0 0 3279718 0 1398378 0 0 3630453 0 0 0 0 0 0 0 1450277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 591809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290380 0 0 0 0 0 0 0 0 0 0 0 0 0 395716 0 0 0 0 385321 518081 0 0 0 0 483494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGVM(Oxidation)HSR MGYG000000271_00943;MGYG000004414_01832;MGYG000004271_01186 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Acetyl-CoA hydrolase transferase 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00943 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGVPADQLR MGYG000004158_00682 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister invisus|m__MGYG000004158 1.0 COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H22W@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 bhbA 1.0 - 1.0 5.4.99.2 1.0 ko:K01848 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00375,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004158_00682 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01848:E5.4.99.2A, mcmA1; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGVSADKLR MGYG000004769_01826;MGYG000000591_01064;MGYG000002659_00371;MGYG000001365_01210 family d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae 1.0 COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H22W@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 bhbA 1.0 - 1.0 5.4.99.2 1.0 ko:K01848 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00375,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01826 0.25 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01848:E5.4.99.2A, mcmA1; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 715135 0 0 0 0 0 0 0 0 0 0 345907 0 0 638801 0 485590 1580680 0 0 0 0 0 0 0 131390 648673 0 0 0 0 0 0 0 0 0 0 0 2861563 0 0 1788651 0 0 0 2873065 0 3108188 0 2923468 0 0 0 0 0 0 0 0 0 0 3086945 0 2994328 0 0 1499342 0 0 0 0 0 2203297 1813158 0 2268289 0 2942850 0 0 3475151 0 0 0 2279005 0 2299898 0 2332695 0 0 2080480 0 1551224 2753754 0 2586270 0 992342 2473393 2176911 2046319 1319585 2841350 0 0 0 0 0 0 0 516252 0 0 450755 911629 0 0 0 0 0 0 786654 0 666920 0 298684 0 0 0 0 188376 1053436 0 809566 461266 0 671399 1174076 907684 0 1107271 1220822 0 0 0 0 0 1332181 1891821 0 2220660 1376501 1520002 0 0 1165715 0 0 0 1110889 0 1191559 2341924 1120509 0 0 1180721 2110721 1412989 1145172 0 733109 1547327 1283779 1125502 1712749 2148742 1520588 1320273 1602829 0 0 2150456 +(Gln->pyro-Glu)QGVSKDEAEDVK MGYG000000179_05048 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_05048 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2717679 0 863553 2173539 0 684711 0 0 2321279 2511909 0 1636688 0 3569466 2939517 1109738 2175198 0 2654333 0 0 1539471 0 1241391 1975523 4223226 2458032 0 0 2486861 0 0 503431 2605245 0 3683138 2908601 1281751 +(Gln->pyro-Glu)QGVSKDEAEDVKAK MGYG000000179_05048 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_05048 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 228188 0 91747 256495 0 0 0 0 263777 277571 0 0 0 0 78094 0 215530 0 256212 0 0 0 0 0 0 103032 195509 0 0 0 0 0 0 0 0 176303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175865 0 0 104276 0 127943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 160330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1448907 0 950216 1918379 0 0 0 0 1790978 1604476 0 0 0 1236640 2073172 0 1580628 0 1430262 2032512 0 0 0 0 0 2642764 1527141 0 0 0 0 0 326436 1241575 0 2281790 2078236 984306 +(Gln->pyro-Glu)QGVSKDEAEDVKAKLEAEGAK MGYG000000179_05048 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_05048 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260171 0 0 0 0 0 0 0 0 0 0 0 0 82791 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 860358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 864891 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QGVSKEEAEDVK MGYG000000198_05826 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_05826 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 1124724 0 0 0 0 0 0 0 0 0 0 0 0 1008550 659176 0 0 0 0 0 0 0 0 0 0 797630 0 0 0 688105 0 0 0 0 623053 1003035 874385 0 496586 0 0 0 0 0 0 0 0 0 0 0 0 594781 397633 0 0 0 0 0 0 0 0 0 0 444629 0 0 0 284492 0 0 0 0 340754 440727 401701 0 1178729 0 0 0 0 0 0 0 0 0 0 0 0 1265638 1269379 0 0 0 0 0 0 0 0 0 0 735141 0 0 0 1038303 0 0 0 0 335549 1177677 1002429 0 634940 0 0 0 0 0 0 0 0 0 0 0 0 607416 348434 0 0 0 0 0 0 0 0 0 0 531639 0 0 0 514009 0 0 0 0 209112 207690 469937 0 321675 0 0 0 0 0 0 0 0 0 0 0 0 0 249354 0 0 0 0 0 0 0 0 0 0 485288 0 0 0 416898 0 0 0 0 400424 297992 594477 0 +(Gln->pyro-Glu)QGYPIGC(Carbamidomethyl)K MGYG000002323_00398;MGYG000003372_01982;MGYG000000235_04528;MGYG000002515_03191;MGYG000002494_02457;MGYG000000093_01127 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0094@1|root,COG0094@2|Bacteria,1MUU9@1224|Proteobacteria,1RPE1@1236|Gammaproteobacteria,3X0U0@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits 1.0 rplE 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02931 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L5,Ribosomal_L5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_00398 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02931:RP-L5, MRPL5, rplE; large subunit ribosomal protein L5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2044655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHAIAAGK MGYG000001300_02022;MGYG000003166_01134 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WG9P@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily 1.0 purB 1.0 - 1.0 4.3.2.2 1.0 ko:K01756 1.0 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 1.0 M00048,M00049 1.0 R01083,R04559 1.0 RC00379,RC00444,RC00445 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADSL_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02022 0.5 adenylosuccinate lyase. succino AMP-lyase. Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole. (1) N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate. (2) (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamide + fumarate. 1.0 1.0 1.0 1.0 Purine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01756:purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 320734 0 0 0 0 0 678341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 594145 0 0 0 0 0 848997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816555 0 0 0 0 0 1693335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317275 0 0 0 0 0 417502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260050 0 0 0 0 0 579993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHALFWADGEPNR MGYG000001378_02163;MGYG000002560_00851;MGYG000002478_02855;MGYG000000098_00878;MGYG000000196_04522;MGYG000002281_01893;MGYG000002549_02754;MGYG000000224_01028;MGYG000000105_02930;MGYG000000243_00155;MGYG000001313_02627;MGYG000002171_02204;MGYG000003681_01113;MGYG000001345_00470;MGYG000000013_01207 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG3630@1|root,COG3630@2|Bacteria,4NV8J@976|Bacteroidetes,2G2DV@200643|Bacteroidia,4AVXB@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 COG NOG19100 non supervised orthologous group 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 LTD,OAD_gamma 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_02163 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 600962 268474 561915 483145 572347 0 0 660342 532646 0 480502 373567 502991 0 685116 599015 0 1947777 701737 0 670172 0 1364100 0 299424 619329 637564 3202432 0 632953 0 528386 645591 0 431274 910076 527137 753548 722784 447008 573637 829711 509244 0 0 787599 740534 0 639689 888855 590787 0 948360 368411 0 0 865358 0 714404 0 282492 0 507554 965692 714223 184414 0 790207 0 790543 602287 0 353139 495247 748418 695775 391489 454189 355418 788719 550069 0 0 310139 607527 0 448285 650929 584998 0 435878 426931 0 671857 355684 0 467268 0 270668 0 500399 527162 611079 471646 0 636015 0 0 353137 0 0 834939 425025 524332 0 345140 0 289640 417145 0 0 0 351765 0 0 450385 186639 0 0 263112 0 0 0 0 0 0 0 0 0 0 0 0 0 313260 0 345655 0 0 0 0 403269 280062 388043 432138 0 0 0 0 0 565358 606262 0 0 0 770555 0 0 660330 0 0 488865 0 0 0 496931 0 243941 273534 534757 0 0 318183 0 0 0 0 550505 0 362323 0 +(Gln->pyro-Glu)QHEVLYYGPQDEAEVK MGYG000000074_01490 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0612@1|root,COG0612@2|Bacteria,4NDXM@976|Bacteroidetes,2FNQC@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Belongs to the peptidase M16 family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M16C_assoc,Peptidase_M16,Peptidase_M16_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01490 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1197904 564015 0 739044 715358 418432 0 834663 1065276 651482 0 858688 458445 334328 301874 760147 825701 0 615652 747698 1346281 0 0 1586857 384530 616488 681499 0 0 677739 0 1102858 725380 0 736264 924353 613492 1735920 1463357 372164 943184 229945 783184 1991977 1148030 1282919 1036655 876784 0 834869 705507 1399948 493905 1363718 744127 0 1432320 569363 1070672 414236 0 761946 195885 381599 620508 0 0 0 0 1204250 732354 0 1876850 745754 503489 878119 322741 0 863271 631041 0 745388 536113 701349 844703 0 0 579390 1296150 0 350177 0 0 0 516540 479916 630232 797485 0 770503 241713 804894 314768 0 716937 637998 0 720642 570587 0 310500 370869 580667 1002892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319704 0 0 0 0 0 0 0 0 0 412566 0 0 543273 549492 685822 1112266 1706760 879820 855825 719478 371815 757723 0 598561 856699 685376 804273 697832 860889 0 1019160 1072440 466231 532402 0 702824 772323 1030435 656974 0 756753 739246 0 685606 621752 0 924574 943184 1254968 1042322 +(Gln->pyro-Glu)QHFLC(Carbamidomethyl)GTGTTAR MGYG000002517_01837 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 methylglyoxal synthase 1.0 mgsA 1.0 - 1.0 2.7.1.24,4.2.3.3 1.0 ko:K00859,ko:K01734 1.0 ko00640,ko00770,ko01100,ko01120,map00640,map00770,map01100,map01120 1.0 M00120 1.0 R00130,R01016 1.0 RC00002,RC00078,RC00424 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoaE,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01837 1.0 dephospho-CoA kinase. | methylglyoxal synthase. dephosphocoenzyme A kinase. Does not act on D-glyceraldehyde 3-phosphate.-!-Formerly EC 4.2.99.11. 3'-dephospho-CoA + ATP = ADP + CoA + H(+). | dihydroxyacetone phosphate = methylglyoxal + phosphate. 1.0 1.0 1.0 1.0 Propanoate metabolism|Pantothenate and CoA biosynthesis|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00859:coaE; dephospho-CoA kinase [EC:2.7.1.24]|K01734:mgsA; methylglyoxal synthase [EC:4.2.3.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 668875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 706506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468896 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHGGDLIFR MGYG000002478_01628 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0008@1|root,COG0008@2|Bacteria,4NEED@976|Bacteroidetes,2FN2D@200643|Bacteroidia,4AKMG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) 1.0 gltX 1.0 - 1.0 6.1.1.17 1.0 ko:K01885 1.0 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 1.0 M00121,M00359,M00360 1.0 R05578 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 1.0 - 1.0 - 1.0 - 1.0 tRNA-synt_1c 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01628 1.0 glutamate--tRNA ligase. glutamyl-tRNA synthetase. - ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu). 1.0 1.0 1.0 1.0 Porphyrin metabolism|Aminoacyl-tRNA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01885:EARS, gltX; glutamyl-tRNA synthetase [EC:6.1.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1037872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHGIDLPFSADNSYSR MGYG000000179_03143 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,26889@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Arginosuccinate synthase 1.0 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03143 1.0 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids|Fluid shear stress and atherosclerosis 1.0 K01940:argG, ASS1; argininosuccinate synthase [EC:6.3.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1180777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHGTHIHPGENVGR MGYG000002919_00595;MGYG000003266_00534;MGYG000000188_00101;MGYG000001642_00797;MGYG000002947_00317 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4CW85@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL27 family 1.0 rpmA 1.0 - 1.0 - 1.0 ko:K02899 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002919_00595 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02899:RP-L27, MRPL27, rpmA; large subunit ribosomal protein L27 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHGYETVVMGASFR MGYG000002494_02911 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0176@1|root,COG0303@1|root,KOG2371@2759|Eukaryota,KOG2772@2759|Eukaryota,3AHVW@33154|Opisthokonta,3BZ72@33208|Metazoa,3DEMK@33213|Bilateria,40QWN@6231|Nematoda,1M0KR@119089|Chromadorea,4171K@6236|Rhabditida 1.0 2759|Eukaryota 1.0 G 1.0 Transaldolase/Fructose-6-phosphate aldolase 1.0 CNX1G 1.0 - 1.0 2.10.1.1,2.2.1.2,2.7.7.75 1.0 ko:K00616,ko:K13168,ko:K15376 1.0 ko00030,ko00790,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04727,map00030,map00790,map01100,map01110,map01120,map01130,map01200,map01230,map04727 1.0 M00004,M00007 1.0 R01827,R09726,R09735 1.0 RC00002,RC00439,RC00604,RC03462 1.0 ko00000,ko00001,ko00002,ko01000,ko03041 1.0 - 1.0 - 1.0 - 1.0 AIRS,DRY_EERY,DUF1244,MoCF_biosynth,MoeA_C,MoeA_N,PgpA,Proteasome,RecA,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02911 1.0 molybdopterin molybdotransferase. | transaldolase. | molybdopterin adenylyltransferase. glycerone transferase. Catalyzes the insertion of molybdenum into the ene-dithiol group of molybdopterin.-!-In eukaryotes this reaction is catalyzed by the N-terminal domain of a fusion protein whose C-terminal domain catalyzes EC 2.7.7.75. | Catalyzes the activation of molybdopterin for molybdenum insertion.-!-In eukaryotes, this reaction is catalyzed by the C-terminal domain of a fusion protein that also includes EC 2.10.1.1.-!-Formerly EC 2.7.7.n5. adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin. | D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | ATP + H(+) + molybdopterin = adenylyl-molybdopterin + diphosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Folate biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|GABAergic synapse 1.0 K00616:TALDO1, talB, talA; transaldolase [EC:2.2.1.2]|K13168:CLASRP, SFRS16; CLK4-associating serine/arginine rich protein|K15376:GPHN; gephyrin [EC:2.10.1.1 2.7.7.75] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 1652601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 908566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 509520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2309273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHLGSEYR MGYG000000254_00984;MGYG000001552_00916;MGYG000003681_01837 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG3391@1|root,COG3391@2|Bacteria,4NJJN@976|Bacteroidetes,2FNI0@200643|Bacteroidia,22Z3Y@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 amine dehydrogenase activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000254_00984 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 3015950 0 2767471 3910304 0 3920284 0 0 3329708 2865294 0 0 0 3470691 0 0 3578924 0 0 0 0 3218022 0 3868740 0 2948117 0 0 0 0 3272087 0 3511647 6342512 3035432 0 3146484 3366223 2438562 0 2750445 2955779 0 1789512 0 0 2902821 2616094 0 0 0 3043607 0 0 1966402 0 0 0 0 2073349 0 1854719 0 2560998 0 0 0 0 1457883 0 2928867 3260592 1874401 0 2465392 3122775 1715156 0 2919476 1733628 0 2894093 0 0 3040539 2065471 0 0 0 2281678 0 0 1981811 0 0 0 0 2276358 0 3425634 0 1552197 0 0 0 0 2699124 0 1866623 1833931 1948643 0 2202031 3025404 668527 0 693998 0 0 0 0 0 543112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 842827 0 0 0 0 0 0 0 1649551 1124575 0 705927 0 1800750 0 2146530 2455283 0 3434002 0 0 3072974 2047429 0 0 0 1244604 0 0 2179070 0 0 0 0 2407642 0 2380451 0 3103906 0 0 0 0 2236485 0 1245907 1456694 2693936 0 2627610 2412477 +(Gln->pyro-Glu)QHLVDIK MGYG000002560_01730;MGYG000001345_00428;MGYG000000042_02678;MGYG000002561_01024;MGYG000003693_00676;MGYG000000013_01171;MGYG000002549_02787;MGYG000001306_03824;MGYG000001337_03683;MGYG000004899_00334;MGYG000003470_01719;MGYG000000243_00095;MGYG000004479_01116;MGYG000000196_04414;MGYG000001789_02092;MGYG000004629_01597;MGYG000001461_03964;MGYG000000029_01835;MGYG000003681_00938;MGYG000001346_02526;MGYG000001489_04394;MGYG000001313_00862;MGYG000002478_04117;MGYG000003221_00209;MGYG000000236_00388;MGYG000001835_01025;MGYG000000415_01202;MGYG000004763_00186 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 0.8571428571428571 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002560_01730 0.03571428571428571 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 1395180 2025750 1714392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2154094 1942468 1680546 1778995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1947537 0 0 0 0 1902826 0 0 0 0 0 0 0 0 0 0 2048755 0 0 0 0 2863751 3739002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4472242 0 0 0 0 0 0 0 0 2436848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1500352 0 0 0 0 0 +(Gln->pyro-Glu)QHLVLNLVSSPGSGK MGYG000002535_00734;MGYG000002494_04480 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0378@1|root,COG0378@2|Bacteria,1MVBD@1224|Proteobacteria,1RN9Y@1236|Gammaproteobacteria,3XNGB@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 KO 1.0 Required for the maturation of the three NiFe hydrogenases. Exhibits a low intrinsic GTPase activity. The GTP hydrolysis catalyzed by HypB is an integral process in the incorporation of nickel into hydrogenases 1.0 hypB 1.0 GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010467,GO:0016151,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:1901564 1.0 - 1.0 ko:K04652 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03110 1.0 - 1.0 - 1.0 - 1.0 cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002535_00734 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04652:hypB; hydrogenase nickel incorporation protein HypB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1190350 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHNDANVLVLPGR MGYG000002293_00079;MGYG000003697_02026 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0698@1|root,COG0698@2|Bacteria,4NNSU@976|Bacteroidetes,2FT1X@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Ribose 5-phosphate isomerase 1.0 rpiB 1.0 - 1.0 5.3.1.6 1.0 ko:K01808 1.0 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01056,R09030 1.0 RC00376,RC00434 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 LacAB_rpiB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00079 0.5 ribose-5-phosphate isomerase. ribose phosphate isomerase. Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate. aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Fructose and mannose metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01808:rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 796515 0 0 612177 0 736931 0 0 815740 0 0 766040 0 0 0 0 0 1301489 0 0 0 881590 1969091 601993 722974 641376 0 1036631 0 0 0 0 0 709840 0 0 768876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244173 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHNITAMNANR MGYG000000398_01963 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__TF01-11|s__|m__MGYG000000398 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000398_01963 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 777419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHNLTAM(Oxidation)NANR MGYG000000398_01070;MGYG000000997_01685;MGYG000002580_01396;MGYG000000076_03207;MGYG000002552_01183;MGYG000000562_01318;MGYG000000398_01963;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000398_01070 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 301233 0 0 471123 0 0 0 0 0 676008 0 0 0 573560 512394 618112 782118 0 0 0 0 0 0 0 0 221342 0 0 0 0 0 0 0 0 0 363256 405975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317657 0 0 546451 0 0 0 0 0 465282 0 0 0 588007 943486 259826 270866 0 0 0 0 0 0 0 0 802998 0 0 0 0 0 0 0 0 0 434263 1099507 0 425183 0 0 0 0 0 0 0 0 618343 0 0 1351001 166158 627582 342853 299916 0 0 0 0 0 0 0 0 421651 0 0 0 0 0 0 0 0 0 0 197229 0 +(Gln->pyro-Glu)QHNLTAMNANR MGYG000000398_01070;MGYG000000997_01685;MGYG000002580_01396;MGYG000000076_03207;MGYG000002552_01183;MGYG000000562_01318;MGYG000000398_01963;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000398_01070 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 2610240 1398708 1150679 4159858 1895908 1776447 1945702 2355048 2813802 3046116 2153875 2949671 2536575 3321334 2661926 1675951 3000670 0 2560001 1423056 2640168 1330687 0 2033190 2174119 2604546 2612060 0 824058 3099599 1261067 1267761 1677335 2649182 2372627 2220027 3136359 1166403 0 0 0 0 0 0 0 0 0 0 0 262525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219256 661570 0 0 506617 0 336861 483717 930724 594787 831604 379202 736252 0 510070 658229 469342 270362 0 570602 629059 0 0 0 0 928764 872995 744561 0 0 822577 213739 0 0 547332 906612 614739 881183 0 1964130 490837 861214 1895311 1298451 980117 1355134 2921690 3077653 1498564 1164416 1758262 1635913 2669719 3883726 1125193 1560715 0 2299877 1580735 2113415 0 0 509722 3783731 3729241 2382986 0 536256 2394200 738697 1028279 731804 4148206 3184582 2410384 4087928 514040 4474022 3102667 2652274 559575 2751734 3127366 1210393 2290806 2424730 6576561 3108470 2003929 6773032 2658380 5606184 2513285 3232513 0 4906001 2519456 2768728 2698369 0 2659294 3819815 3576662 4232609 0 1136131 3276986 2351699 2620683 3801046 4185784 4994764 3643135 4129317 2410546 +(Gln->pyro-Glu)QHNMQAANANR MGYG000002670_01665;MGYG000002670_01663;MGYG000002492_03078;MGYG000001141_00820 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.75 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002670_01665 0.25 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407702 0 573176 0 0 0 0 0 651152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466133 0 0 0 0 488811 0 0 275167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310244 0 0 0 0 216434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHNVEGTVYDDAAK MGYG000003686_01440 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4|s__ER4 sp000765235|m__MGYG000003686 1.0 COG1404@1|root,COG1404@2|Bacteria,1UM3J@1239|Firmicutes 1.0 1239|Firmicutes 1.0 O 1.0 S-layer homology domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003686_01440 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2110602 0 0 0 0 1945563 0 0 0 0 2177718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHPSFK MGYG000001789_01676 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002161565|m__MGYG000001789 1.0 COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,2FSHU@200643|Bacteroidia,4AQXS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001789_01676 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02884:RP-L19, MRPL19, rplS; large subunit ribosomal protein L19 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 706800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1296034 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 684744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 925422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1161852 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHTPGYDPNAK MGYG000002293_02142;MGYG000002960_01872;MGYG000003697_01320 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1187@1|root,COG1187@2|Bacteria,4NEE1@976|Bacteroidetes,2FP7M@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the pseudouridine synthase RsuA family 1.0 rluB 1.0 - 1.0 5.4.99.22 1.0 ko:K06178 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03009 1.0 - 1.0 - 1.0 - 1.0 PseudoU_synth_2,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_02142 0.3333333333333333 23S rRNA pseudouridine(2605) synthase. - Pseudouridine synthase RluB converts uridine(2605) of 23S rRNA to pseudouridine. uridine(2605) in 23S rRNA = pseudouridine(2605) in 23S rRNA. 1.0 1.0 1.0 1.0 - 1.0 K06178:rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599269 0 0 0 0 0 0 0 988339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 863491 0 0 0 0 963982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHTSFVVR MGYG000000074_00430 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 28X6E@1|root,2ZJ4T@2|Bacteria,4P99Y@976|Bacteroidetes,2FZDY@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00430 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 927813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHVIYK MGYG000002494_02289;MGYG000002323_04134;MGYG000002506_03286 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,3X2KI@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL28 family 1.0 rpmB 1.0 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02902 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02289 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02902:RP-L28, MRPL28, rpmB; large subunit ribosomal protein L28 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2019997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2216022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHVLYK MGYG000002535_04391;MGYG000002477_00502;MGYG000002534_00101;MGYG000002494_02289;MGYG000003372_03385;MGYG000002515_03800;MGYG000002323_04134;MGYG000002506_03286;MGYG000002476_00305;MGYG000002504_04504 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0227@1|root,COG0227@2|Bacteria,1MZ57@1224|Proteobacteria,1S8UG@1236|Gammaproteobacteria,3X2KI@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL28 family 1.0 rpmB 1.0 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02902 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002535_04391 0.1 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02902:RP-L28, MRPL28, rpmB; large subunit ribosomal protein L28 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2490818 0 0 0 2338015 0 0 0 0 970125 0 0 0 0 0 1801264 2638258 0 0 1879424 0 0 0 2488304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187634 0 0 0 0 0 0 0 0 429941 0 0 0 0 0 0 0 0 0 0 0 0 0 95948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325227 0 0 0 0 416918 0 0 0 0 0 193575 0 0 0 73759 0 0 0 121472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QHVPVFVTDEMVGHK MGYG000001708_01470;MGYG000002534_00396;MGYG000002507_04185;MGYG000000235_04536;MGYG000002494_02465;MGYG000002477_00183;MGYG000002323_00390;MGYG000002500_04421;MGYG000002504_03960;MGYG000002506_02957;MGYG000002515_03199 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0185@1|root,COG0185@2|Bacteria,1RGYX@1224|Proteobacteria,1S5VT@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA 1.0 rpsS 1.0 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02965 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001708_01470 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02965:RP-S19, RSM19, rpsS; small subunit ribosomal protein S19 1.0 none 1.0 466352 427577 293085 323314 162563 662019 557590 726677 608229 680292 0 0 0 647083 542921 0 150447 0 324094 498170 628128 577869 0 580248 636282 0 283429 0 166637 0 452902 0 374276 358611 651211 590587 257590 170532 823003 825256 1105128 957869 1234502 2359812 1054646 980298 708227 1697269 0 0 0 1062091 891732 0 1185097 0 1481178 935501 1134489 2153823 0 1611226 1141263 892673 1143704 0 1521733 964709 411899 0 909373 844460 857814 765834 732406 731729 175760 0 237245 0 359889 622821 0 0 0 174117 0 0 0 213632 352424 0 0 0 0 184578 249349 482364 0 443247 265573 0 357409 0 418393 157241 0 0 206383 400191 359783 411072 0 0 301753 204987 176752 78008 390482 579802 327760 202927 241651 797455 0 0 0 0 194558 0 192507 0 215985 275490 175205 603883 0 585979 212037 0 0 0 0 537751 199729 0 339737 337093 388036 162720 346778 385260 0 0 0 0 265231 0 0 0 0 0 0 0 0 197133 0 0 0 0 0 0 0 171301 0 161442 328548 0 89505 0 0 0 0 0 0 0 0 0 220241 0 +(Gln->pyro-Glu)QIADKYGVPHISTGDIFR MGYG000000271_01082 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism 1.0 adk 1.0 - 1.0 2.7.4.3 1.0 ko:K00939 1.0 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 1.0 M00049 1.0 R00127,R01547,R11319 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS20110 1.0 ADK,ADK_lid 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_01082 1.0 adenylate kinase. myokinase. Inorganic triphosphate can also act as donor. AMP + ATP = 2 ADP. 1.0 1.0 1.0 1.0 Purine metabolism|Thiamine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00939:adk, AK; adenylate kinase [EC:2.7.4.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIADKYSIPHISTGDIFR MGYG000002517_02852 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism 1.0 adk 1.0 - 1.0 2.7.4.3 1.0 ko:K00939 1.0 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 1.0 M00049 1.0 R00127,R01547,R11319 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS20110 1.0 ADK,ADK_lid 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02852 1.0 adenylate kinase. myokinase. Inorganic triphosphate can also act as donor. AMP + ATP = 2 ADP. 1.0 1.0 1.0 1.0 Purine metabolism|Thiamine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00939:adk, AK; adenylate kinase [EC:2.7.4.3] 1.0 none 1.0 0 0 0 0 0 1211487 0 0 0 0 0 0 0 1577809 0 0 0 0 0 0 0 1058995 0 896795 493607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 616969 0 0 0 0 0 0 0 510986 0 0 0 0 0 0 0 738221 0 580401 806923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 619560 0 0 0 0 0 0 0 563966 0 0 0 0 0 0 0 684401 0 468073 897540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234833 0 0 0 0 0 0 0 459250 0 0 0 0 0 0 0 309530 0 680137 440548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1398127 0 0 0 0 0 0 0 2164352 0 0 0 0 0 0 0 0 0 44951 2370153 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIASNAGMEGAIVAEKVK MGYG000004158_00394 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister invisus|m__MGYG000004158 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4H29X@909932|Negativicutes 1.0 909932|Negativicutes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 - 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004158_00394 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIC(Carbamidomethyl)DIGRR MGYG000000200_00392;MGYG000001338_00134;MGYG000000252_02294;MGYG000000133_00165;MGYG000002966_00348;MGYG000002298_02773;MGYG000004733_01681;MGYG000000171_01273;MGYG000000212_01008;MGYG000002298_00038;MGYG000000301_01359 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3WHFE@541000|Ruminococcaceae 0.5454545454545454 186801|Clostridia 1.0 G 1.0 L-fuculose phosphate aldolase 0.5454545454545454 fucA 0.5454545454545454 - 1.0 4.1.2.17 1.0 ko:K01628 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R02262 1.0 RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000200_00392 0.09090909090909091 L-fuculose-phosphate aldolase. L-fuculose-1-phosphate lactaldehyde-lyase. - L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01628:fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] 1.0 none 1.0 0 0 946489 0 0 0 175486 0 521123 0 1058106 0 0 0 0 1220736 0 0 826155 0 0 0 0 0 0 0 0 0 0 0 0 0 862896 496983 0 0 0 950930 0 0 0 0 0 0 409916 0 550137 0 388921 0 0 0 0 130974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374836 305616 0 0 0 382549 0 0 1266958 0 0 0 826930 0 932513 0 820139 0 0 0 0 1054756 0 0 1394263 0 0 0 0 0 0 0 0 0 0 0 0 0 1451669 1598253 0 0 0 998222 0 0 502757 0 0 0 0 0 635032 0 372417 0 0 0 0 541186 0 0 339674 0 0 0 0 0 0 0 0 0 0 0 0 0 475655 0 0 0 0 522691 0 0 2082464 0 0 0 2326850 0 1871333 0 2621540 0 0 0 0 1580827 0 0 2271059 0 0 0 0 0 0 0 0 0 0 0 0 0 3108591 2602347 0 0 0 1796407 +(Gln->pyro-Glu)QIDKNEAR MGYG000002619_02370;MGYG000002274_00828;MGYG000002610_01878;MGYG000002040_00986;MGYG000000195_02117;MGYG000000022_02024;MGYG000002641_00972;MGYG000002651_00731 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3WJ8R@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002619_02370 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 729945 683125 973593 914376 0 218624 485449 362424 660642 0 0 0 0 936985 0 0 304363 181261 718596 380891 0 616153 802426 668666 497615 701794 523682 1264530 0 213238 0 304665 1257979 1289916 0 0 651177 692675 1698018 1747496 2087486 2231916 0 1878629 2639213 976120 2317806 0 0 0 0 2908673 2527768 0 2784795 1780166 3098255 2191973 1187140 1434594 3298156 1464415 3343746 2340903 2730074 2867663 0 1959811 0 1717168 2617632 2425535 0 0 1472969 2011509 0 0 0 0 0 0 188519 0 0 0 0 0 0 0 0 0 0 1954799 0 0 152726 0 1539904 0 0 0 0 1317937 0 0 0 0 0 0 0 0 0 0 541659 599952 1556729 726965 0 1013951 924109 415293 882389 0 0 0 0 827692 1176016 0 512093 747536 1277760 797313 536438 1039663 920139 649969 1427277 959071 771511 687640 0 1248104 0 877886 1261043 1998276 0 0 1150725 1072262 0 0 0 148926 0 0 0 0 0 0 0 0 0 0 0 0 0 1810060 0 0 0 0 1401468 0 0 0 0 1885743 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIEDNKDALK MGYG000000223_00973 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG2222@1|root,COG2222@2|Bacteria,1TQUT@1239|Firmicutes,3VP6T@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 M 1.0 Sugar isomerase, AgaS family 1.0 - 1.0 - 1.0 - 1.0 ko:K02082 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 SIS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_00973 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02082:agaS; D-galactosamine 6-phosphate deaminase/isomerase [EC:3.5.99.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 703929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 983175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIEEEIVEVGKR MGYG000003542_01378;MGYG000003469_00458;MGYG000000053_00926;MGYG000002082_01733;MGYG000000074_01808 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia,22U4P@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Endoribonuclease that initiates mRNA decay 1.0 rny 1.0 - 1.0 - 1.0 ko:K18682 1.0 ko03018,map03018 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03019 1.0 - 1.0 - 1.0 - 1.0 DUF3552,HD,KH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003542_01378 0.2 - - - - 1.0 1.0 1.0 1.0 RNA degradation 1.0 K18682:rny; ribonucrease Y [EC:3.1.-.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIEEQSDKLIR MGYG000002279_01084;MGYG000002992_00601;MGYG000000038_01565 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24AN3@186801|Clostridia,27WHN@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 RnfC Barrel sandwich hybrid domain 1.0 prdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,RnfC_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_01084 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIEETTSDFDREK MGYG000000919_03652;MGYG000000202_00541;MGYG000002992_01078;MGYG000000038_02089;MGYG000003486_00745;MGYG000001607_00737;MGYG000001496_00484;MGYG000000278_02028;MGYG000000179_05119;MGYG000001615_01161;MGYG000000198_00464;MGYG000002445_00865;MGYG000000217_01904;MGYG000003783_01372;MGYG000001367_02937;MGYG000001688_01574;MGYG000001617_04641;MGYG000004087_02347;MGYG000000262_01443;MGYG000001193_01063;MGYG000002247_01828;MGYG000002279_00394 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,21YIV@1506553|Lachnoclostridium 0.4090909090909091 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.9545454545454546 MGYG000000919_03652 0.045454545454545456 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 804839 0 0 779264 0 0 264381 0 410229 427367 0 478942 358930 893964 739502 0 796262 877000 512861 844137 816073 0 514864 0 0 563320 391159 768228 0 894804 0 0 0 270954 0 986150 264131 0 0 0 0 347227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217053 0 0 0 0 0 0 0 0 0 0 0 1213642 0 739584 1489351 0 0 1078218 0 921032 829862 0 991904 650315 1199459 1442548 0 846791 0 917033 1096099 1355289 0 0 0 0 1100431 1253671 396761 0 1211338 0 0 852599 1282828 0 984193 1042206 629429 602695 0 320157 477650 0 0 445963 0 508143 508684 0 291439 312927 181340 0 0 536345 0 313045 478823 580304 0 0 0 0 341714 780376 0 0 427003 0 0 337570 734236 0 700670 466904 509681 1521269 0 876445 861116 0 0 1681932 0 1651923 1615350 0 786955 445075 1112226 1746475 0 1349353 0 1424196 1518241 1236383 0 0 0 0 1545045 1496793 540341 0 923470 0 0 1066680 2405864 0 994374 1661974 1019564 +(Gln->pyro-Glu)QIGGGLVTAMVR MGYG000002494_04005;MGYG000003372_01152;MGYG000002477_02044;MGYG000002534_03547 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG4576@1|root,COG4577@1|root,COG4576@2|Bacteria,COG4577@2|Bacteria,1RIK4@1224|Proteobacteria,1S6GW@1236|Gammaproteobacteria,3ZNAY@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 CQ 1.0 Ethanolamine utilisation protein EutN/carboxysome 1.0 eutN 1.0 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 1.0 - 1.0 ko:K04028 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC,EutN_CcmL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04005 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04028:eutN; ethanolamine utilization protein EutN 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426245 494555 629856 674343 0 567987 637648 684558 443940 948749 337806 650693 0 591932 647838 0 600794 0 635165 503519 622109 588249 0 487190 610626 565209 665392 0 0 863100 0 588250 574996 610225 0 0 518865 364147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 43348 0 0 0 73536 0 0 0 0 0 0 0 0 0 0 0 115927 0 143846 125225 0 0 0 0 0 0 0 41744 0 0 0 0 0 0 0 0 339635 0 560336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136164 0 0 0 46323 0 0 0 0 0 0 0 0 0 0 0 493302 +(Gln->pyro-Glu)QIGPSNIAAGESDEVK MGYG000002517_02160 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2182@1|root,COG2182@2|Bacteria,1VRPK@1239|Firmicutes,24Y63@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02160 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K15770:cycB, ganO, mdxE; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein 1.0 none 1.0 210373 495711 405181 500378 0 603786 355315 0 575629 902697 449040 473250 0 407671 225991 517413 456402 0 435315 248619 0 400951 0 656175 444247 460429 700229 0 0 0 410139 0 435235 584653 675012 750561 616743 438104 0 444905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 528834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209909 0 0 0 0 394312 662659 600427 406230 0 352980 775526 0 575533 425211 408454 555884 0 371872 398293 0 433154 0 433372 459118 0 417164 0 349410 640511 427397 478735 0 0 0 779137 0 376360 717168 304427 586792 260376 461664 718719 199339 621555 839827 0 330200 504059 0 874052 336732 498146 536595 0 1274719 913604 641681 745821 0 886187 791974 0 350677 0 299479 799734 871548 743501 0 0 0 385909 0 0 0 1103219 858490 894318 400087 1195007 1001477 1863090 1119376 0 1516970 1671450 0 1722053 1301901 1354345 1466790 0 1068049 1675449 1098374 1474395 0 1322101 1091240 0 826722 0 1737480 2166843 1908892 1538003 0 0 0 1299785 0 1869397 2202839 1274889 1064228 2092310 0 +(Gln->pyro-Glu)QIGQTGVTVHPK MGYG000002960_00220;MGYG000003697_02505;MGYG000002603_00030;MGYG000002293_02659;MGYG000001306_03030 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia 0.8 976|Bacteroidetes 1.0 C 1.0 Electron transfer flavoprotein 0.8 etfA 1.0 - 1.0 - 1.0 ko:K03522 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002960_00220 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 625494 0 0 0 0 852843 0 0 0 0 704175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1408692 0 0 1302204 0 0 0 0 0 0 0 0 0 0 0 1612301 0 0 0 1308544 1524881 957620 0 0 0 1597748 0 0 0 0 1174025 0 0 0 0 1247112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278009 0 0 0 0 269557 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIGQTGVTVRPK MGYG000000013_01113;MGYG000004830_00491;MGYG000002181_01061;MGYG000004464_00650;MGYG000002281_01803;MGYG000001346_02512;MGYG000003469_01112;MGYG000003554_01591;MGYG000000224_01764;MGYG000004885_01161;MGYG000001370_00111;MGYG000001313_00856;MGYG000003420_00108;MGYG000003521_01088;MGYG000001661_01629;MGYG000002549_02818;MGYG000000673_00584;MGYG000001659_01714;MGYG000003922_03089;MGYG000000196_04139;MGYG000004876_02153;MGYG000001378_04598;MGYG000000138_01469;MGYG000000825_02222;MGYG000003221_01664;MGYG000002033_00723;MGYG000003926_00355;MGYG000004720_00561;MGYG000001489_04895;MGYG000003367_00837;MGYG000002721_00910;MGYG000000029_01804;MGYG000004824_01248;MGYG000000243_00604;MGYG000003498_00874;MGYG000000054_02441;MGYG000001503_00716;MGYG000002275_00940;MGYG000001666_00851;MGYG000004638_00871;MGYG000004748_00350;MGYG000002218_00406;MGYG000003460_00807;MGYG000001345_00397;MGYG000003535_01795;MGYG000003952_01067;MGYG000000098_00812;MGYG000001337_03725;MGYG000002560_03243;MGYG000000105_03056;MGYG000003542_01687;MGYG000000354_00401;MGYG000001630_00164;MGYG000001429_00436;MGYG000002478_00354;MGYG000003423_01173;MGYG000002438_02892;MGYG000003681_02880;MGYG000001643_03097;MGYG000000044_02111 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia,4AKN9@815|Bacteroidaceae 0.45 976|Bacteroidetes 0.9833333333333333 C 1.0 Psort location Cytoplasmic, score 8.96 0.45 etfA 0.8833333333333333 - 1.0 - 0.9833333333333333 ko:K03522 0.8666666666666667 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko04147 0.8666666666666667 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha 0.8166666666666667 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_01113 0.016666666666666666 - - - - 0.9833333333333333 0.9833333333333333 0.9833333333333333 0.9833333333333333 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit 0.8666666666666667 none 1.0 1394681 1605797 1519758 1320820 1773580 1217603 1564763 1306319 1177703 1180488 1442838 1409251 1445792 1494551 1500403 2051772 1579453 884883 1235914 1418978 1420623 1201121 979166 1826433 1231390 1523994 1535990 959494 1217765 1285945 1412319 1551571 2074396 1565556 1583253 1413741 1399887 1590465 1511002 1025949 1527510 1721983 1571389 1324175 1081629 1570236 1477678 1496799 1708079 1781297 1267666 1397831 1268502 1262193 1210552 496751 1491294 1052403 1347605 1218132 723100 845546 1320465 1403097 1388265 884805 1184914 1530792 814998 1229212 1107335 1247739 1532003 1225405 1722015 1348668 886674 914663 1282174 903275 1464032 1253481 1108460 873418 1034801 844025 1483721 1011476 1238423 985491 933682 1279933 989823 1530541 1104018 973631 980400 1113390 1658229 1069842 1070809 874404 843513 1470768 1103618 1401950 1341572 880326 987717 806703 1145149 981590 986953 937277 834963 1049334 996672 782790 814804 779647 850877 929172 934371 930739 919909 1215991 1079927 875446 804948 936029 775429 732767 808183 686118 1176221 823606 633545 646157 1059313 1220687 717399 577852 846682 971844 785987 1105549 980287 1088809 1522299 1190950 1112224 763696 864565 910678 933360 1265677 1298719 1440786 1188194 1268190 1424243 917230 1271238 1367515 1176117 885849 978299 1561626 1183027 1462239 1185474 1152686 1211454 1107863 1524984 1110399 1075699 1165857 894341 1098675 930448 2260156 1023453 1327284 582572 1333232 1357296 810648 1423139 1010083 +(Gln->pyro-Glu)QIGVTLPHLK MGYG000002478_00678;MGYG000004797_01301;MGYG000000243_02708 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0235@1|root,COG0235@2|Bacteria,4NIQK@976|Bacteroidetes,2FN5U@200643|Bacteroidia,4AN95@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases 1.0 rhaD 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 1.0 4.1.2.19 1.0 ko:K01629 1.0 ko00040,ko00051,ko01120,map00040,map00051,map01120 1.0 - 1.0 R01785,R02263 1.0 RC00438,RC00599,RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00678 0.3333333333333333 rhamnulose-1-phosphate aldolase. L-rhamnulose-phosphate aldolase. - L-rhamnulose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01629:rhaD; rhamnulose-1-phosphate aldolase [EC:4.1.2.19] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644417 0 0 0 0 427928 0 0 0 0 410091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 129376 0 0 0 0 104147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 824224 0 0 0 0 920032 0 0 0 0 732687 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIGYQPYEDEGKIK MGYG000000133_00899 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1879@1|root,COG1879@2|Bacteria,1TSUI@1239|Firmicutes,24BR7@186801|Clostridia,26BK5@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K02058 1.0 - 1.0 M00221 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1.2 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00899 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02058:ABC.SS.S; simple sugar transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1724427 0 0 0 1471286 0 0 0 0 1514689 0 0 2810567 0 0 0 2990726 0 0 0 0 0 0 0 0 0 0 0 0 1650883 2128069 0 0 0 0 1436432 +(Gln->pyro-Glu)QIIAEVDAIC(Carbamidomethyl)R MGYG000001338_01864;MGYG000000216_03383;MGYG000000184_02632;MGYG000000142_01112;MGYG000004296_00030;MGYG000002025_00748;MGYG000000200_00055;MGYG000003821_00296;MGYG000003012_02009 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,3Y0ZT@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 4Fe-4S dicluster domain 1.0 - 1.0 - 1.0 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.0 ko:K03388 1.0 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 1.0 M00356,M00357,M00563,M00567 1.0 R04540,R11928,R11931,R11943,R11944 1.0 RC00011 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Fer4,Fer4_10,Fer4_7,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01864 0.1111111111111111 ferredoxin:CoB-CoM heterodisulfide reductase. | coenzyme F420:CoB-CoM heterodisulfide,ferredoxin reductase. | H2:CoB-CoM heterodisulfide,ferredoxin reductase. | formate:CoB-CoM heterodisulfide,ferredoxin reductase. - HdrABC is an enzyme complex that is found in most methanogens and catalyzes the reduction of the CoB-CoM heterodisulfide back to CoB and CoM.-!-HdrA contains a FAD cofactor that acts as the entry point for electrons, which are transferred via HdrC to the HdrB catalytic subunit.-!-One form of the enzyme from Methanosarcina acetivorans (HdrA2B2C2) can also catalyze EC 1.8.98.4. cf. EC 1.8.98.5, EC 1.8.98.6, and EC 1.8.98.1. | The enzyme, characterized from the archaeon Methanosarcina acetivorans, catalyzes the reduction of CoB-CoM heterodisulfide back to CoB and CoM.-!-The enzyme consists of three components, HdrA, HdrB and HdrC, all of which contain [4Fe-4S] clusters.-!-Electrons enter at HdrA, which also contains FAD, and are transferred via HdrC to the catalytic component, HdrB.-!-During methanogenesis from acetate the enzyme catalyzes the activity of EC 1.8.7.3.-!-However, it can also use electron bifurcation to direct electron pairs from reduced coenzyme F420 toward the reduction of both ferredoxin and CoB-CoM heterodisulfide.-!-This activity is proposed to take place during Fe(III)-dependent anaerobic methane oxidation. cf. EC 1.8.98.5, EC 1.8.98.6, and EC 1.8.98.1. | This enzyme complex is found in H2-oxidizing CO2-reducing methanogenic archaea such as Methanothermobacter thermautotrophicus.-!-It consists of a cytoplasmic complex of HdrABC reductase and MvhAGD hydrogenase.-!-Electron pairs donated by the hydrogenase are transferred via its Delta subunit to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide.-!-The reductase can also form a similar complex with formate dehydrogenase, see EC 1.8.98.6, formate:CoB-CoM heterodisulfide,ferredoxin reductase. cf. EC 1.8.7.3, EC 1.8.98.4, and EC 1.8.98.1. | The enzyme is found in formate-oxidizing CO2-reducing methanogenic archaea such as Methanococcus maripaludis.-!-It consists of a cytoplasmic complex of HdrABC reductase and formate dehydrogenase.-!-Electron pairs donated by formate dehydrogenase are transferred to the HdrA subunit of the reductase, where they are bifurcated, reducing both ferredoxin and CoB-CoM heterodisulfide. cf. EC 1.8.7.3, EC 1.8.98.4, EC 1.8.98.5, and EC 1.8.98.1. coenzyme B + coenzyme M + 2 oxidized [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | coenzyme B + coenzyme M + 4 H(+) + 2 oxidized coenzyme F420-(gamma-L- Glu)(n) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 reduced coenzyme F420-(gamma-L-Glu)(n). | coenzyme B + coenzyme M + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 H2 + 2 oxidized [2Fe-2S]- [ferredoxin]. | 2 CO2 + coenzyme B + coenzyme M + 2 reduced [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 formate + 2 oxidized [2Fe-2S]- [ferredoxin]. 1.0 1.0 1.0 1.0 Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03388:hdrA2; heterodisulfide reductase subunit A2 [EC:1.8.7.3 1.8.98.4 1.8.98.5 1.8.98.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIIEADIPMSGLFGYC(Carbamidomethyl)TDLR MGYG000002247_02135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Acetatifactor|s__Acetatifactor sp900771995|m__MGYG000002247 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,27JEC@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Elongation factor G, domain IV 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002247_02135 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 847962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIIGVIDR MGYG000002494_04127 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3WV6W@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 K 1.0 Transcriptional regulator PadR-like family 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04127 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1470348 0 0 730403 1155973 0 0 0 0 770599 0 1123828 0 0 0 858220 1244946 0 890439 868354 0 0 0 0 0 0 0 0 569196 506100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIKDFSLGGFAR MGYG000002478_00657;MGYG000002560_00458 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKGC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02014 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00657 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02014:TC.FEV.OM; iron complex outermembrane recepter protein 1.0 none 1.0 0 0 0 0 720995 0 0 0 0 0 0 0 792474 0 0 797320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287339 0 0 0 0 0 0 0 319508 0 0 365513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 130630 0 0 0 0 0 0 0 178926 0 0 259823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 872093 0 0 0 0 0 0 0 527497 0 0 875445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167917 0 0 0 0 0 0 0 143504 0 0 476965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIKEAVAAKK MGYG000001315_01866 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,27IGM@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01866 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIKYPLAAK MGYG000000133_00306;MGYG000001338_00214;MGYG000000142_02314;MGYG000000212_00040;MGYG000000002_02500;MGYG000000146_01483 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia 0.8333333333333334 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00306 0.16666666666666666 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 324453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 494006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1606854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIKYPLAAKDEQGR MGYG000000133_00306;MGYG000001338_00214;MGYG000000171_02641 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00306 0.3333333333333333 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 0 0 0 0 0 0 96809 0 0 0 0 0 100763 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 712117 824048 0 0 0 228409 0 0 519348 0 0 639807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704351 0 468543 0 1182882 0 0 0 0 495358 +(Gln->pyro-Glu)QIKYPLSAK MGYG000000271_00603;MGYG000002963_04223;MGYG000000204_01913;MGYG000004740_01385;MGYG000001637_01052;MGYG000000356_01714;MGYG000001319_00739;MGYG000002670_00089;MGYG000002836_02134;MGYG000001219_01350;MGYG000002992_01076;MGYG000000198_00495;MGYG000000193_00312;MGYG000003695_02134;MGYG000004869_03402;MGYG000004879_00512;MGYG000000164_00891;MGYG000004271_01872;MGYG000004087_02343;MGYG000001315_00701;MGYG000002517_01047;MGYG000001645_00506;MGYG000002492_02315;MGYG000002279_00396 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia 0.2916666666666667 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00603 0.041666666666666664 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 1809818 2081379 0 0 0 0 0 0 0 0 0 0 0 0 0 2245971 2008915 0 0 0 0 2027322 0 0 0 0 2311787 0 0 0 0 1965739 0 0 0 0 1810816 0 439244 446942 0 0 0 0 0 0 0 0 0 0 0 0 0 582524 712026 0 0 0 0 496607 0 0 0 0 763808 0 0 0 0 739797 0 0 0 0 644953 0 1618939 1620421 0 0 0 0 0 0 0 0 0 0 0 0 0 1049410 1303470 0 0 0 0 1539845 0 0 0 0 1504772 0 0 0 0 1577822 0 0 0 0 1393754 0 880600 926598 0 0 0 0 0 0 0 0 0 0 0 0 0 929249 1232878 0 0 0 0 870041 0 0 0 0 1432282 0 0 0 0 940879 0 0 0 0 1092603 0 455515 977462 0 0 0 0 0 0 0 0 0 0 0 0 0 681553 1033797 0 0 0 0 0 0 0 0 0 1386297 0 0 0 0 918787 0 0 0 0 883792 +(Gln->pyro-Glu)QILEIISQNAR MGYG000001461_00185;MGYG000002933_01451;MGYG000000029_02715;MGYG000002549_03412;MGYG000000781_00112;MGYG000001789_02087;MGYG000001661_01271;MGYG000003221_02267;MGYG000004899_00478;MGYG000002455_01329;MGYG000001345_04455;MGYG000003922_01960;MGYG000002478_01011;MGYG000002281_04321;MGYG000003693_00243;MGYG000000054_02904;MGYG000002470_01569;MGYG000001337_04159;MGYG000004185_02372;MGYG000001750_00997;MGYG000001925_01762;MGYG000003312_01840;MGYG000002560_03655;MGYG000001364_02711;MGYG000001787_00015;MGYG000003351_03113;MGYG000004019_02623;MGYG000001780_02391;MGYG000004748_01119;MGYG000001599_01405;MGYG000000098_00470;MGYG000001783_01941;MGYG000002935_00927;MGYG000002171_00554;MGYG000000236_04556;MGYG000004797_01237;MGYG000003681_02173;MGYG000004876_01322;MGYG000002561_00327;MGYG000004479_02768;MGYG000000224_00608;MGYG000000105_01860;MGYG000001313_00277;MGYG000001346_02074;MGYG000000273_00327;MGYG000000043_02680;MGYG000001370_01791;MGYG000003252_03222;MGYG000000243_03093;MGYG000002291_02066;MGYG000001378_00204;MGYG000001306_02191;MGYG000000196_04706;MGYG000000013_02428 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1522@1|root,COG1522@2|Bacteria,4NMEN@976|Bacteroidetes,2FMP2@200643|Bacteroidia,4AM91@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 Transcriptional regulator, AsnC family 1.0 asnC 1.0 - 1.0 - 1.0 ko:K03718 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 AsnC_trans_reg,HTH_24,HTH_AsnC-type 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001461_00185 0.018518518518518517 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03718:asnC; Lrp/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5301552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QILGTHVAQK MGYG000002494_04513 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,3ZKEI@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04513 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01872:AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550876 0 462494 0 0 0 0 517796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QILLDTYYGR MGYG000002323_02346;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 1.0 adhE 1.0 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_02346 0.25 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 112883 0 0 182669 0 0 0 69669 0 97877 0 0 0 0 0 0 0 79370 0 402744 0 223983 0 0 0 0 0 104763 0 113603 0 0 0 0 0 0 2069867 3508958 4138185 2565020 3429364 4644980 3849559 1682086 2678387 3442205 0 2032396 1482866 2856668 2436013 1982176 3402340 0 4012515 2379287 2842027 3683807 0 3636576 3295433 2297737 2509045 0 4523849 3630209 1126311 1707195 3176991 2176219 1884960 1807435 2374109 2301858 0 211421 0 0 96456 323366 76872 131163 108741 77064 0 174539 65992 73279 204638 172103 64772 0 111778 52072 0 371510 0 758856 153019 305528 114663 0 104043 0 322178 73580 89378 137923 0 223998 202175 147203 0 1365446 132684 0 0 0 590020 0 0 0 0 0 1215668 0 1283083 0 0 0 0 0 0 61669 0 0 0 0 0 0 99555 0 0 2838254 0 0 0 0 0 0 0 85874 0 0 0 177518 0 0 2050537 0 0 0 0 0 0 0 0 0 4760 0 0 0 0 0 0 0 5218 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QILLDTYYGRDYVEGETAAKK MGYG000002506_00529 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 1.0 adhE 1.0 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00529 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 402438 0 0 988242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 953297 0 716167 0 0 0 0 0 0 0 0 366310 0 0 0 0 344833 0 0 0 0 0 280209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 129658 0 0 203102 0 0 1336536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692206 0 690019 0 0 0 0 0 0 0 0 426635 0 0 0 0 430756 0 0 453588 0 0 554911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762613 0 424571 0 0 0 0 0 0 0 0 480033 0 0 0 0 152459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QILSGIK MGYG000001617_01701;MGYG000000198_00821 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,21Z1B@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 J 1.0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation 1.0 metG 1.0 - 1.0 6.1.1.10 1.0 ko:K01874 1.0 ko00450,ko00970,map00450,map00970 1.0 M00359,M00360 1.0 R03659,R04773 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,tRNA-synt_1g,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 GH84 1.0 MGYG000001617_01701 0.5 methionine--tRNA ligase. MetRS. In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9. ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met). 1.0 1.0 1.0 1.0 Selenocompound metabolism|Aminoacyl-tRNA biosynthesis 1.0 K01874:MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10] 1.0 none 1.0 0 0 0 0 0 528074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 560352 0 452534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 198346 0 289370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1292716 0 438058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2925971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1597129 0 1657263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362044 0 495512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QILVQENDYVR MGYG000003312_01247;MGYG000001306_02654;MGYG000000183_03082;MGYG000002560_00228;MGYG000002935_00902;MGYG000003693_02792;MGYG000002455_03893;MGYG000001378_05033;MGYG000000243_01979;MGYG000001346_01525;MGYG000000105_01994;MGYG000001313_00088;MGYG000000224_00483;MGYG000000442_01373;MGYG000001345_04693;MGYG000000400_00966;MGYG000004757_00585;MGYG000004885_00605;MGYG000001920_01196;MGYG000000170_00064;MGYG000000196_03983;MGYG000004720_01708;MGYG000002549_02931;MGYG000002478_00805;MGYG000000042_01430;MGYG000001789_00145;MGYG000003351_04372;MGYG000004797_04274;MGYG000000054_03942;MGYG000002762_01078;MGYG000004105_01519;MGYG000001608_02201;MGYG000000236_01798;MGYG000004763_01698;MGYG000002291_02263;MGYG000003681_02045;MGYG000002556_01323 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 0.7297297297297297 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 0.972972972972973 MGYG000003312_01247 0.02702702702702703 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 8056448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1636637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIMTEIINSHSDMEM(Oxidation)VATAPDPLVAR MGYG000002506_01275;MGYG000002494_03454 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2201@1|root,COG2201@2|Bacteria,1MWCN@1224|Proteobacteria,1RN67@1236|Gammaproteobacteria,3XNVQ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 NT 1.0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR 1.0 cheB 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006482,GO:0006807,GO:0006935,GO:0008150,GO:0008152,GO:0008214,GO:0008984,GO:0009605,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0018277,GO:0019538,GO:0019899,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051723,GO:0052689,GO:0070988,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1990827 1.0 3.1.1.61,3.5.1.44 1.0 ko:K03412 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheB_methylest,Response_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_01275 0.5 protein-glutamate methylesterase. | protein-glutamine glutaminase. protein methyl-esterase. | peptidoglutaminase II. Hydrolyzes the products of EC 2.1.1.77, EC 2.1.1.78, EC 2.1.1.80 and EC 2.1.1.100. | Specific for the hydrolysis of the gamma-amide of glutamine substituted at the carboxyl position or both the alpha-amino and carboxyl positions, e.g., L-glutaminylglycine and L-phenylalanyl-L- glutaminylglycine. [protein]-L-glutamate 5-O-methyl ester + H2O = H(+) + L-glutamyl- [protein] + methanol. | H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+). 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03412:cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QINAAESR MGYG000001313_01931;MGYG000002455_02656;MGYG000001346_03599;MGYG000003681_00353 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4372@1|root,COG4372@2|Bacteria,4NJGZ@976|Bacteroidetes,2G2H0@200643|Bacteroidia,4AKNU@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_01931 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 667473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 508201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QINC(Carbamidomethyl)HIVDK MGYG000002438_00957 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22XE6@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 MGYG000002438_00957 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QINDEIMAQIMEAITK MGYG000000212_00440;MGYG000000133_02955;MGYG000000184_00575;MGYG000000171_00241;MGYG000001338_02151 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.6 186801|Clostridia 1.0 G 1.0 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 0.6 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000212_00440 0.2 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QINEAENRVDLQSGSIR MGYG000000243_03188;MGYG000002478_01929 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,2FNI1@200643|Bacteroidia,4AVYV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03188 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 1224062 0 799613 0 0 0 0 0 0 0 900679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 871190 0 1104495 0 0 0 0 1106470 0 0 0 0 284065 0 0 0 0 0 0 0 684184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264588 0 0 511230 0 423115 0 0 0 0 0 0 0 393600 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178307 0 0 0 0 0 0 0 397324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248557 0 354024 0 0 0 0 362531 +(Gln->pyro-Glu)QINKDLAIQFK MGYG000000243_02696;MGYG000002171_02452 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FWW6@200643|Bacteroidia,4AWE3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02696 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 1527671 0 1213884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1609258 0 1585262 0 0 0 0 1498954 0 0 277517 0 482833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 200213 0 0 0 0 0 0 292757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIQVDLPDIGHR MGYG000002274_01087;MGYG000002641_01949;MGYG000003899_02100;MGYG000002272_00718;MGYG000001300_02656;MGYG000003166_00234;MGYG000003291_01552 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 translation elongation 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_01087 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 413384 397819 226751 0 904929 0 236206 0 0 170417 0 0 0 0 670716 0 454835 0 0 0 0 0 0 0 0 292342 0 0 835749 0 0 0 0 0 0 0 364759 0 662980 524766 0 0 339298 693199 598989 0 0 448352 0 0 449963 0 583250 0 291793 0 0 195619 0 0 0 503439 386384 0 0 373288 0 0 0 0 0 0 0 0 269378 0 0 0 0 0 457180 0 0 0 0 224816 0 0 0 0 0 0 547866 0 0 0 0 0 0 388105 132485 312750 0 486604 433926 0 0 0 0 0 0 0 259751 0 365956 291771 421741 0 595564 419536 466409 0 0 514288 0 0 174153 0 775241 0 453659 0 0 248019 0 0 0 298207 390501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128959 0 0 0 0 0 0 0 0 0 231393 0 237381 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIQVELPDIGHR MGYG000004679_00212 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000004679 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 translation elongation 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004679_00212 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449858 0 0 0 0 427102 0 0 0 0 793129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1072072 0 0 0 0 0 0 0 0 0 624617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 944756 0 0 0 0 1152973 0 0 0 0 999003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609843 0 0 0 0 902912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1458325 0 0 0 0 1665636 0 0 0 0 2168002 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIQVYAEDAAK MGYG000002478_02937;MGYG000004797_02944;MGYG000002560_02890;MGYG000000236_02416 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02937 0.25 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K01802:E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]|K03770:ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1218773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1206713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QISAMILQK MGYG000000153_02121;MGYG000000245_00866;MGYG000002517_00989;MGYG000000271_02474;MGYG000002256_00937;MGYG000004271_00836;MGYG000000280_00287 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 0.8571428571428571 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000153_02121 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 70618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 501453 0 0 714894 0 0 0 0 496596 0 0 0 0 0 573264 110110 476392 0 0 431370 0 0 0 0 0 396278 1007265 0 0 0 0 0 0 0 0 481505 378510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QISIAHIAR MGYG000000003_02555;MGYG000004536_01074;MGYG000001562_00614;MGYG000001420_00222 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,2FP6Q@200643|Bacteroidia,22U4U@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Succinate dehydrogenase fumarate reductase 1.0 frdB 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00240 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer2_3,Fer4_7,Fer4_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_02555 0.25 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00240:sdhB, frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] 1.0 none 1.0 543812 0 0 0 0 0 0 0 0 734502 0 0 0 0 0 0 0 0 1131002 0 0 0 0 0 0 695067 2158955 0 0 1578026 0 1545111 0 0 0 0 1511232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467040 0 0 0 0 0 0 0 0 399047 0 0 0 0 0 0 0 0 422151 0 0 0 0 0 0 0 610514 0 0 384762 0 275023 0 0 0 0 412853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121136 0 0 0 0 0 0 0 116478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QITEDTDKVIR MGYG000001306_02215 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,2FN99@200643|Bacteroidia,22WPD@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 seryl-tRNA synthetase 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_02215 1.0 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01875:SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 701671 0 0 0 0 526086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438497 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QITGKEPSK MGYG000000153_02121;MGYG000000179_03775;MGYG000002517_00989;MGYG000000271_02474;MGYG000000489_01891;MGYG000000133_02344;MGYG000000142_01918;MGYG000000255_01223;MGYG000001065_01063 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 0.4444444444444444 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000153_02121 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 262455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1559485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QITITELGQR MGYG000002494_04127 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3WV6W@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 K 1.0 Transcriptional regulator PadR-like family 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04127 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 460311 0 554444 0 0 0 0 0 0 0 0 0 0 0 0 0 724309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 648271 0 0 0 1517201 0 1662150 1657145 2749399 0 0 0 1567584 0 0 0 0 0 0 0 1366239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 420407 0 0 0 0 0 782953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226833 0 0 0 0 0 0 0 0 0 0 0 0 191629 0 652933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 515177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QITLAHVITSPKPIVYR MGYG000000262_00817;MGYG000000077_01079 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG4810@1|root,COG4810@2|Bacteria,1V452@1239|Firmicutes,25DMT@186801|Clostridia,25ZJH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 E 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 ko:K04031 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_00817 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04031:eutS; ethanolamine utilization protein EutS 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534054 0 0 0 0 0 0 0 0 0 0 0 0 531005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 497008 0 433493 0 0 0 0 497814 +(Gln->pyro-Glu)QITMDTQDYTNNEK MGYG000001300_02598;MGYG000002641_02082;MGYG000002651_01603;MGYG000003899_02002;MGYG000002610_01434;MGYG000002272_02331;MGYG000003166_00861;MGYG000002274_01203 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02598 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788882 0 0 0 0 728800 0 0 0 0 687181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 767840 0 0 0 0 680681 0 0 0 0 830709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1369043 0 0 0 0 1349770 0 0 0 0 1452975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363835 0 0 0 0 540076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QITVSVIDPVGLHAR MGYG000000223_03916;MGYG000001421_00895 family d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae 1.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,3VR4T@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 G 1.0 phosphocarrier protein HPr 1.0 ptsH 1.0 - 1.0 - 1.0 ko:K11189 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_03916 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K11189:- 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1514720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 344620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QITVSVIDPVGLHARPATVAVNAASK MGYG000000223_03916 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,3VR4T@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 G 1.0 phosphocarrier protein HPr 1.0 ptsH 1.0 - 1.0 - 1.0 ko:K11189 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_03916 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K11189:- 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 954868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246699 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIVANAGK MGYG000002470_00024;MGYG000000355_02196;MGYG000001503_00482;MGYG000000044_03505;MGYG000000013_01093;MGYG000001661_02480;MGYG000003693_01240;MGYG000001313_00852;MGYG000002478_00380;MGYG000003363_02977;MGYG000003521_02097;MGYG000002171_01748;MGYG000000224_01773;MGYG000002218_01379;MGYG000000105_03063;MGYG000004899_00357;MGYG000003922_03103;MGYG000001925_02203;MGYG000002933_01569;MGYG000001787_00205;MGYG000004876_02137;MGYG000001306_00685;MGYG000001433_02375;MGYG000001364_01313;MGYG000003251_00039;MGYG000001345_00379;MGYG000004763_01826;MGYG000000243_00634;MGYG000002033_00862;MGYG000002438_00745;MGYG000001337_03744;MGYG000002455_00111;MGYG000001346_02504;MGYG000001489_00629;MGYG000001461_03937;MGYG000000236_02963;MGYG000000098_00786;MGYG000001789_02329;MGYG000003681_02583;MGYG000000138_02067;MGYG000001370_00105 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 0.7560975609756098 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002470_00024 0.024390243902439025 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 450278 0 0 0 0 0 0 0 0 0 0 0 85151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 569389 0 0 0 0 0 0 0 0 0 0 0 753816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1127927 0 0 0 0 0 0 0 0 0 0 0 279525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIVANAGKEGAVVVQK MGYG000002470_00024;MGYG000001503_00482;MGYG000000044_03505;MGYG000000013_01093;MGYG000001661_02480;MGYG000001313_00852;MGYG000002478_00380;MGYG000002171_01748;MGYG000000224_01773;MGYG000000105_03063;MGYG000004899_00357;MGYG000001925_02203;MGYG000003922_03103;MGYG000002933_01569;MGYG000004876_02137;MGYG000001345_00379;MGYG000004763_01826;MGYG000000243_00634;MGYG000002033_00862;MGYG000001337_03744;MGYG000002455_00111;MGYG000001346_02504;MGYG000000236_02963;MGYG000000098_00786;MGYG000001789_02329;MGYG000000138_02067;MGYG000003681_02583;MGYG000001370_00105 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 0.8571428571428571 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002470_00024 0.03571428571428571 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 466393 1090795 2084825 0 1566294 1007746 0 925582 0 969303 1126691 0 1745067 1091984 0 1498316 1546156 0 718616 0 642653 622123 0 867719 0 591541 0 0 0 846414 1593717 1400760 1799024 0 855663 0 845297 1619713 0 0 0 0 364636 0 0 0 0 0 279816 0 286624 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141903 0 0 0 0 0 0 0 339804 710907 0 676263 690449 0 463064 0 520199 682013 0 641668 336331 0 625150 328193 0 0 0 147070 387370 0 391784 0 281908 0 0 0 384126 653706 468294 444481 0 576356 0 0 379949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268393 0 0 0 0 0 243595 0 384925 0 0 450358 0 0 0 0 634664 0 0 0 0 0 0 0 0 313300 194968 151797 0 0 0 0 352838 0 +(Gln->pyro-Glu)QIVDHK MGYG000001311_00418;MGYG000000489_01431;MGYG000000301_00189;MGYG000000142_02037;MGYG000004055_01474;MGYG000001338_02781;MGYG000002528_01865;MGYG000000205_02177;MGYG000000164_02738;MGYG000001374_01170;MGYG000001698_04057;MGYG000000255_01813;MGYG000004271_00043;MGYG000001793_01088;MGYG000002298_00361;MGYG000004317_00991;MGYG000001319_01295;MGYG000000251_01802;MGYG000000233_02370;MGYG000000187_01733;MGYG000001310_00114;MGYG000004733_01001;MGYG000000242_01797;MGYG000002279_01045;MGYG000001193_00570;MGYG000002989_00885;MGYG000000216_02330;MGYG000002835_01006;MGYG000000031_02237;MGYG000000198_04914;MGYG000000154_01811;MGYG000000271_01088;MGYG000000146_01023;MGYG000000206_01061;MGYG000001496_03147;MGYG000000002_00856;MGYG000002517_02847;MGYG000000404_01611;MGYG000000179_04573;MGYG000000080_02281;MGYG000002492_00402;MGYG000004296_00416;MGYG000002145_00311 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia 0.27906976744186046 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001311_00418 0.023255813953488372 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 3731126 3545450 4163044 2402175 0 3217843 0 0 0 3831285 4928664 3721177 5380734 3861369 4522374 0 2539238 4972861 0 0 4550434 5634716 4619932 2435577 4260272 3651256 0 5635533 3520185 0 2258393 0 3230672 5027269 4275702 2872517 3397289 3082526 2252870 6236310 2592473 3307064 0 1898971 0 0 0 2823243 2829824 2161019 3650576 2291453 2277447 0 2854548 2482627 0 0 1916758 1281358 1880509 2627424 2337091 2565459 0 4297195 3269090 0 5200937 0 3355597 4181397 3677328 3004069 2897085 3528405 3724665 6066278 4750481 3018353 0 4328583 0 0 0 4005249 2834128 3129336 5002999 5030746 4705825 0 5083301 2586312 0 0 2596813 5577037 2823899 3188418 4805468 4494192 0 4881177 4397789 0 3808605 0 7414404 5333879 4159331 3634217 2678886 3884099 3451623 3438628 3462702 3651397 0 1954391 0 0 0 3805126 3370198 3703668 2993791 3029566 3917662 0 2802204 1974176 0 0 1073619 3043112 865209 3452462 3216354 2777121 0 3067011 3800446 0 4756113 0 3221745 2488103 3940770 2401890 3938796 4088828 6313152 8360105 5349555 5804034 0 5477816 0 0 0 9586945 8208787 5704792 3073823 13042168 7821677 0 6914514 723621 0 0 4357474 4018700 1829409 5127022 7332199 6449152 0 3221686 9717926 0 5622031 0 11114420 8683742 6903981 11575072 6654020 8747536 +(Gln->pyro-Glu)QIVDHKFVTVN(Deamidated)GK MGYG000004271_00043;MGYG000000154_01811;MGYG000000153_02069 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00043 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIVDHKHVLVN(Deamidated)GK MGYG000001193_00570;MGYG000002989_00885;MGYG000000142_02037;MGYG000004055_01474;MGYG000000216_02330;MGYG000002835_01006;MGYG000000031_02237;MGYG000001338_02781;MGYG000002528_01865;MGYG000004839_01287;MGYG000000164_02738;MGYG000000002_00856;MGYG000000404_01611;MGYG000002298_00361;MGYG000004317_00991;MGYG000001319_01295;MGYG000004296_00416;MGYG000000187_01733;MGYG000000251_01802;MGYG000001310_00114;MGYG000002279_01045;MGYG000004733_01001 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia 0.18181818181818182 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001193_00570 0.045454545454545456 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIVEISRRPEFLGK MGYG000002478_03891;MGYG000000044_00878;MGYG000000243_02790;MGYG000001780_04144 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,2FQ21@200643|Bacteroidia,4AMWE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Protein of unknown function (DUF3417) 1.0 glgP 1.0 - 1.0 2.4.1.1,2.4.1.11,2.4.1.8 1.0 ko:K00688,ko:K00691,ko:K16153 1.0 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 1.0 - 1.0 R00292,R01555,R02111 1.0 RC00005,RC00049 1.0 ko00000,ko00001,ko01000,ko01003 1.0 - 1.0 GH65,GT3,GT35 1.0 - 1.0 DUF3417,Glycogen_syn,Phosphorylase 1.0 2.4.1.1 1.0 GT35 1.0 GT35 1.0 GT35 1.0 MGYG000002478_03891 0.25 glycogen phosphorylase. | glycogen(starch) synthase. | maltose phosphorylase. polyphosphorylase. | UDP-glucose--glycogen glucosyltransferase. This entry covers several enzymes from different sources that act in vivo on different forms of (1->4)-alpha-D-glucans.-!-Some of these enzymes catalyze the first step in the degradation of large branched glycan polymers - the phosphorolytic cleavage of alpha-1,4-glucosidic bonds from the non-reducing ends of linear poly(1->4)-alpha-D-glucosyl chains within the polymers.-!-The enzyme stops when it reaches the fourth residue away from an alpha-1,6 branching point, leaving a highly branched core known as a limit dextrin.-!-The description (accepted name) of the enzyme should be modified for each specific instance by substituting 'glycogen' with the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, etc. | The description (official name) varies according to the source of the enzyme and the nature of its synthetic product.-!-Glycogen synthase from animal tissues is a complex of a catalytic subunit and the protein glycogenin.-!-The enzyme requires glucosylated glycogenin as a primer; this is the reaction product of EC 2.4.1.186.-!-A similar enzyme utilizes ADP-glucose (cf. EC 2.4.1.21). [(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. | [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D- glucosyl](n+1) + H(+) + UDP. | D-maltose + phosphate = beta-D-glucose 1-phosphate + D-glucose. 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biofilm formation - Escherichia coli|Necroptosis|Insulin signaling pathway|Glucagon signaling pathway|Insulin resistance 1.0 K00688:PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]|K00691:mapA; maltose phosphorylase [EC:2.4.1.8]|K16153:K16153; glycogen phosphorylase/synthase [EC:2.4.1.1 2.4.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIVENAGGEGSVVVNK MGYG000001562_02467;MGYG000000074_00757;MGYG000001546_00436;MGYG000001415_01066;MGYG000000003_00613;MGYG000003279_00515 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22UPC@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000001562_02467 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 288352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355341 0 0 0 0 0 409914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 500380 0 0 0 0 0 0 +(Gln->pyro-Glu)QIVENAGGEGSVVVNKVK MGYG000000074_00757;MGYG000000003_00613 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22UPC@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000074_00757 0.5 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 258438 0 0 175454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376304 0 0 0 0 0 0 0 0 0 0 353679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 752955 0 0 0 0 0 0 0 0 757383 0 0 0 0 0 0 0 0 0 0 0 0 352255 0 0 0 0 0 0 0 0 0 0 610269 0 +(Gln->pyro-Glu)QIVGFLKDGC(Carbamidomethyl)EK MGYG000000029_02971;MGYG000003312_01933;MGYG000004763_00834;MGYG000000013_04188;MGYG000001306_01782;MGYG000001750_00741;MGYG000000196_03462;MGYG000001787_00809;MGYG000002478_03726;MGYG000001345_02371;MGYG000003681_00721;MGYG000000098_01490;MGYG000001346_03050 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,4AKZ7@815|Bacteroidaceae 0.46153846153846156 976|Bacteroidetes 1.0 S 0.46153846153846156 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 0.5384615384615384 serA 0.5384615384615384 - 1.0 1.1.1.399,1.1.1.95 0.5384615384615384 ko:K00058 0.5384615384615384 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 0.5384615384615384 M00020 0.5384615384615384 R01513 0.5384615384615384 RC00031 0.5384615384615384 ko00000,ko00001,ko00002,ko01000,ko04147 0.5384615384615384 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 0.5384615384615384 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000029_02971 0.07692307692307693 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 0.5384615384615384 0.5384615384615384 0.5384615384615384 0.5384615384615384 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.5384615384615384 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 0.5384615384615384 none 1.0 0 0 0 0 848981 685723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726276 0 0 0 0 0 614559 0 0 0 0 356964 224536 0 0 0 0 0 0 208903 0 0 0 0 0 0 0 0 304610 0 0 0 0 0 0 0 0 0 453423 251796 0 0 0 0 315250 0 0 460838 0 0 380502 0 0 0 0 0 0 343807 0 0 0 0 0 0 0 0 214280 0 0 0 0 0 0 0 0 0 349623 359953 0 0 0 0 0 0 0 214348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIVGFLKDGC(Carbamidomethyl)EKFR MGYG000002478_03726 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_03726 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIVLN(Deamidated)C(Carbamidomethyl)GEEPSVVANTVK MGYG000002515_04060;MGYG000002507_03180;MGYG000002494_02676;MGYG000002323_03824;MGYG000003390_03600;MGYG000002506_03866 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,3XN1I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002515_04060 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797417 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 696784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIVLNC(Carbamidomethyl)GEEPSVVANTVK MGYG000002515_04060;MGYG000002507_03180;MGYG000002494_02676;MGYG000002323_03824;MGYG000003390_03600;MGYG000002506_03866 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,3XN1I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002515_04060 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 439703 390143 292850 442811 314618 519255 353733 531669 0 493077 0 412182 388429 0 0 0 733756 0 453819 714588 0 413901 357199 0 0 0 488731 438334 0 352516 0 332262 566381 288092 0 242569 614281 1157413 897035 988588 1320131 2186586 1064140 882346 676976 1344672 588785 1177021 0 1053560 1129391 0 1251971 0 1332451 781543 1447653 2639952 0 1904997 1434832 943153 957350 0 1557262 1571482 0 1036529 1188496 778043 927826 686864 863164 1036148 514500 297233 0 0 448926 624528 491304 417336 489373 538248 283160 546532 0 0 431239 0 0 0 300655 473593 435861 337482 0 557471 560982 212854 0 0 362858 421016 0 536262 547509 500342 494697 462953 0 0 437950 470928 150319 0 291403 497769 0 307180 0 358415 0 433803 0 0 0 0 0 0 345864 0 0 516624 0 0 296109 0 0 0 230588 0 0 340392 299536 476462 449472 421181 0 346067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIVSHGHVAVN(Deamidated)GR MGYG000002485_02438;MGYG000004893_02153;MGYG000004828_01832 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia,36DJ1@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 S 1.0 Amidohydrolase family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_02438 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 260261 0 0 0 0 0 0 0 573774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 536799 0 0 0 0 829186 0 0 830696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115070 0 0 0 0 485715 0 0 195427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348171 0 0 0 0 0 0 0 718715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399219 0 0 0 0 0 0 0 121881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIWLAR MGYG000002385_01670;MGYG000002836_00177;MGYG000000417_00990;MGYG000003425_04578;MGYG000000135_00904;MGYG000002835_00249;MGYG000000194_00148;MGYG000003074_01094;MGYG000002494_00954;MGYG000004740_00996;MGYG000004296_00563;MGYG000001466_01401;MGYG000000093_03264;MGYG000003365.1_01350;MGYG000002279_01345;MGYG000000198_05003;MGYG000000028_00551;MGYG000003386_02757;MGYG000002502_02035;MGYG000002513_00644;MGYG000000077_00742;MGYG000003500_01570;MGYG000000204_01919;MGYG000000337_00504;MGYG000000164_02309;MGYG000000650_00409;MGYG000004785_01595;MGYG000001714_03187;MGYG000002477_03371;MGYG000000251_00849;MGYG000002445_00508;MGYG000001637_00295;MGYG000001602_00896;MGYG000002140_02930;MGYG000000187_00017;MGYG000004719_00198;MGYG000003390_04838;MGYG000000280_00495;MGYG000004140_02145;MGYG000002415_03008;MGYG000004087_02771;MGYG000003381_00971;MGYG000001688_02232;MGYG000000242_00002;MGYG000000262_01894;MGYG000000233_01926;MGYG000003147_00384;MGYG000001027_00595;MGYG000004697_00980;MGYG000004691_01780;MGYG000004271_02671;MGYG000002247_02698;MGYG000000249_02765;MGYG000002500_02076;MGYG000004735_02560;MGYG000000172_02251;MGYG000000278_01794;MGYG000002772_02101;MGYG000002323_01869;MGYG000001617_03101;MGYG000000206_00307;MGYG000001379_00357;MGYG000000087_00675;MGYG000003184_02040;MGYG000004687_00694;MGYG000000909_00003;MGYG000000274_00640;MGYG000002534_02304;MGYG000002670_01394;MGYG000002212_01212;MGYG000000076_00222;MGYG000002492_01782;MGYG000000245_00328;MGYG000000140_00409;MGYG000000216_00894;MGYG000000325_00749;MGYG000002170_01655;MGYG000004842_00865;MGYG000001619_00780;MGYG000001607_01170;MGYG000000378_00736;MGYG000003360_04047;MGYG000003394_00456;MGYG000004313_00821;MGYG000004869_03499;MGYG000000179_01982;MGYG000004762_00052;MGYG000000255_00435;MGYG000003335_00558;MGYG000002552_01270;MGYG000001622_02998;MGYG000000038_00405;MGYG000000032_00759;MGYG000000127_02757;MGYG000001493_01515;MGYG000000312_00898;MGYG000001311_02799;MGYG000002256_02331;MGYG000001564_02958;MGYG000001065_01098;MGYG000000235_02801;MGYG000003702_00971;MGYG000002476_01918;MGYG000000205_01312;MGYG000002535_02257;MGYG000002528_02185;MGYG000000133_01122;MGYG000003427_02320;MGYG000001624_00366;MGYG000000271_00159;MGYG000001689_03339;MGYG000001615_01544;MGYG000000562_01465;MGYG000004879_02884;MGYG000000136_00740;MGYG000001319_00516;MGYG000001543_01619;MGYG000001531_01857;MGYG000001315_00603;MGYG000003486_01852;MGYG000002517_01594 domain d__Bacteria 1.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,22068@1506553|Lachnoclostridium 0.256198347107438 186801|Clostridia 0.8016528925619835 J 1.0 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit 1.0 rplT 1.0 - 0.8016528925619835 - 1.0 ko:K02887 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002385_01670 0.008264462809917356 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02887:RP-L20, MRPL20, rplT; large subunit ribosomal protein L20 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIYMAQAAESGKPEAIQEK MGYG000003266_00511;MGYG000002961_01439;MGYG000002775_01737;MGYG000001718_01380;MGYG000001642_01010;MGYG000004681_00360;MGYG000002919_00618;MGYG000000802_00143;MGYG000000188_00077 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CU7J@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003266_00511 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 684665 0 0 0 0 0 0 0 0 0 0 453807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QIYVDHTK MGYG000000133_00237;MGYG000000216_00421 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 0.5 186801|Clostridia 1.0 M 0.5 Cobalt chelatase (CbiK) 0.5 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00237 0.5 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKAEADIAQER MGYG000003166_00739;MGYG000000195_00670;MGYG000001300_02372;MGYG000002619_01674;MGYG000000022_01424;MGYG000004679_00017;MGYG000002274_00872;MGYG000002545_01161;MGYG000002040_00949 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24IT1@186801|Clostridia,3WS1Z@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) 1.0 - 1.0 - 1.0 - 1.0 ko:K02109 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_B 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_00739 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02109:ATPF0B, atpF; F-type H+-transporting ATPase subunit b 1.0 none 1.0 3858420 0 5529745 3032394 0 4166001 218982 4811860 4243122 0 6284411 0 0 866264 3449878 6291149 3396963 2214685 4149850 4188073 0 3346120 531898 4151621 4052007 4444383 3214758 3011132 0 0 0 0 4501510 0 0 3521611 4379342 4707379 792894 0 806106 962524 0 465256 788664 1304603 786295 0 627063 0 0 764255 659088 563598 785457 381775 1472244 646909 0 528282 751397 517678 1003428 705682 665869 784282 0 0 0 0 818895 0 0 444435 680213 513977 348307 0 3678952 372351 0 3224866 466833 255268 3550072 0 4311417 0 0 391523 2205020 3025617 2234051 966107 2124096 885175 0 1841141 627340 183536 404148 238395 247514 616007 0 0 0 0 2109429 0 0 3492766 352770 3311280 1926467 0 1277397 1062067 0 1885205 1258456 1986333 958335 0 2469843 0 0 1278583 1782231 2507449 996267 891686 1488417 838425 0 0 841836 1010673 1278484 2489579 1997500 1383784 0 0 0 0 1647583 0 0 1442849 2040637 0 259449 0 287196 163835 0 131643 205341 65091 168379 0 445989 0 0 277966 139166 435894 408330 464353 416472 213501 0 377361 502228 382066 162678 364140 370924 541818 0 0 0 0 84638 0 0 294398 230128 398971 +(Gln->pyro-Glu)QKAEGLKR MGYG000002478_04161;MGYG000004797_00893 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0404@1|root,COG0404@2|Bacteria,4NF7S@976|Bacteroidetes,2FPDM@200643|Bacteroidia,4AMEQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 The glycine cleavage system catalyzes the degradation of glycine 1.0 gcvT 1.0 - 1.0 2.1.2.10 1.0 ko:K00605 1.0 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 1.0 M00532 1.0 R01221,R02300,R04125 1.0 RC00022,RC00069,RC00183,RC02834 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GCV_T,GCV_T_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_04161 0.5 aminomethyltransferase. tetrahydrofolate aminomethyltransferase. A component, with EC 1.4.4.2 and EC 1.8.1.4, of the glycine cleavage system, formerly known as glycine synthase.-!-The glycine cleavage system is composed of four components that only loosely associate: the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H protein. (6S)-5,6,7,8-tetrahydrofolate + N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]- L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + N(6)- [(R)-dihydrolipoyl]-L-lysyl-[protein] + NH4(+). 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Glyoxylate and dicarboxylate metabolism|One carbon pool by folate|Metabolic pathways|Biosynthesis of secondary metabolites|Carbon metabolism 1.0 K00605:gcvT, AMT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 188271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKAEVTIPAK MGYG000002517_00434 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00434 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K05808:hpf; ribosome hibernation promoting factor 1.0 none 1.0 0 0 0 0 0 0 0 358630 257009 0 0 0 0 0 0 0 0 0 0 0 0 283481 0 0 147670 286030 218048 0 0 299049 0 0 0 0 546824 298698 190735 0 292921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394261 0 0 398485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246981 153893 159093 284314 0 0 188400 0 0 0 0 200903 151599 277403 0 1822427 0 0 0 0 0 0 1721560 1581962 0 0 0 0 1695293 1727067 0 1373328 0 1402717 0 0 0 0 0 1891935 1671631 2032808 0 0 1477940 0 0 0 0 1691319 1567963 1745790 0 911803 0 0 0 0 930086 0 897232 1197157 0 0 0 0 1168317 1417987 0 1069674 0 1344646 0 0 844748 0 844126 1128622 1453258 1038486 0 0 622672 0 0 0 0 828865 1169076 1043096 0 +(Gln->pyro-Glu)QKDFAASDR MGYG000000133_01279 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3XZ2A@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01279 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3485735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2470043 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKDFLAK MGYG000001338_02036;MGYG000004869_01160 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001338_02036 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359854 0 0 0 0 0 +(Gln->pyro-Glu)QKDLSIVYTPLHGAGR MGYG000001313_01236;MGYG000002455_04364;MGYG000001346_01418;MGYG000002717_00478 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001313_01236 0.25 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 592206 0 0 0 0 636065 0 0 0 0 591652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385749 0 0 0 0 316874 0 0 0 0 409977 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKDVYNIVLAC(Carbamidomethyl)HDK MGYG000000243_01741 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0006@1|root,COG0006@2|Bacteria,4NG40@976|Bacteroidetes,2FMSQ@200643|Bacteroidia,4AKGR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 pepP 1.0 - 1.0 3.4.11.9 1.0 ko:K01262 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 AMP_N,Peptidase_M24 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01741 1.0 Xaa-Pro aminopeptidase. X-Pro aminopeptidase. Generally membrane bound enzyme present in both mammalian and bacterial cells.-!-Belongs to peptidase family M24B. Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide. 1.0 1.0 1.0 1.0 - 1.0 K01262:pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9] 1.0 none 1.0 0 0 434202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519871 0 0 0 0 391903 0 0 206698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242286 0 0 0 0 291255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKEAATENENR MGYG000000179_01759 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,268IA@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 O 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_01759 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKEAVTELFR MGYG000003542_00743;MGYG000003415_00398;MGYG000000074_01933;MGYG000002082_00458;MGYG000000053_00721 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,2FNPH@200643|Bacteroidia,22UFD@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal protein L17 1.0 rplQ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02879 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Ribosomal_L17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003542_00743 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02879:RP-L17, MRPL17, rplQ; large subunit ribosomal protein L17 1.0 none 1.0 468815 0 282122 309517 435807 487715 0 322749 316644 417716 0 0 0 0 273667 329758 344877 0 0 150451 0 389829 0 550593 311957 279247 0 0 458932 457104 249573 0 388721 0 0 399064 303611 266986 0 0 426598 453083 571679 498593 0 392395 0 576790 0 0 0 0 421097 289194 169472 0 0 0 0 306744 0 369586 0 520090 0 0 546630 391865 190265 0 371758 0 0 391647 563839 292386 298346 0 0 358074 350095 432944 0 404277 809027 984116 0 0 0 0 806743 378631 650585 0 0 352307 0 0 0 319582 774392 190139 0 0 604034 268026 0 0 819469 0 0 605249 616836 336771 147530 0 626726 299743 340467 456557 0 483867 343665 292233 0 0 0 0 301765 466906 340342 0 425468 276778 0 518884 0 613599 377942 464333 0 0 405035 415099 374075 0 485716 0 0 415564 345782 471293 752647 0 922225 1452335 1119077 1262382 0 809291 1222233 1078768 0 0 0 0 967947 1145363 1107679 0 1695046 1677330 0 938012 0 840233 1108891 1124028 0 0 1202998 1448393 849205 0 595852 0 0 1035014 1404455 1077516 +(Gln->pyro-Glu)QKEIADGLASAER MGYG000002494_02408;MGYG000002506_03406;MGYG000002534_04893;MGYG000002477_00658;MGYG000002535_04275 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,3X0ZA@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) 1.0 atpF 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902600 1.0 - 1.0 ko:K02109 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664 1.0 ATP-synt_B 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02408 0.2 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02109:ATPF0B, atpF; F-type H+-transporting ATPase subunit b 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613728 0 0 631086 1296790 0 0 0 1138089 0 0 0 0 0 0 1360070 0 0 0 0 989741 0 1334095 0 0 0 0 0 1785895 0 0 0 568145 0 0 0 0 0 0 0 0 496651 435603 0 0 0 0 0 0 0 0 0 0 749688 0 0 0 0 562936 0 0 0 0 0 0 0 1069914 0 0 0 910971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 592136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKEISAFIVEK MGYG000000164_00686;MGYG000000255_01556;MGYG000004740_00273;MGYG000001793_01807;MGYG000000205_02133 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,21YI4@1506553|Lachnoclostridium 0.4 186801|Clostridia 1.0 C 0.6 Acyl-CoA dehydrogenase, C-terminal domain 0.6 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_00686 0.2 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 885384 0 912128 0 0 958381 0 794276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 844552 0 0 0 0 648983 0 0 0 0 0 0 0 0 0 0 346254 0 423316 0 0 222526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397526 0 0 0 0 0 0 0 0 0 0 114812 0 0 0 0 437020 0 244954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194892 0 0 0 0 0 0 0 0 0 0 0 0 469343 0 0 584691 0 503971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424215 0 0 0 0 635199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKELGYHVITDGEFR MGYG000002528_03006 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,248U0@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 methionine synthase, vitamin-B12 independent 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Meth_synt_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_03006 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 892524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 673276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKELMER MGYG000002966_01704;MGYG000000806_02010;MGYG000000133_01628;MGYG000000301_00396;MGYG000003821_00638;MGYG000003012_01436 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3XZ91@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 9.98 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002966_01704 0.16666666666666666 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1|K03527:ispH, lytB; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] 1.0 none 1.0 0 809563 541984 0 0 396579 0 0 0 0 683303 0 1019366 0 0 537485 0 0 0 0 0 0 0 223804 503008 1885388 0 0 594533 0 0 211120 654455 0 0 1446743 0 829662 0 0 0 438060 0 0 0 0 0 0 138117 0 0 0 0 0 0 0 0 0 0 0 0 111910 0 130137 0 0 0 0 0 442664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321569 0 0 0 0 0 0 0 362108 333696 245092 0 0 0 126682 0 0 0 0 0 158316 0 502824 0 113281 0 0 5708119 0 0 295355 129419 0 0 0 344789 0 0 1819864 1265751 641584 0 260388 1040117 0 0 1713866 1657119 486181 801577 1569910 0 480127 0 0 155669 0 1582423 0 0 0 605288 315873 0 0 1117658 0 0 2019293 4918225 0 0 258617 0 887308 +(Gln->pyro-Glu)QKELQDMAQR MGYG000001346_02373;MGYG000002561_01358;MGYG000000224_01894;MGYG000003363_00932;MGYG000001313_00712;MGYG000004748_02076;MGYG000001661_00082;MGYG000003681_01828 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2825@1|root,COG2825@2|Bacteria,4NWPA@976|Bacteroidetes,2G3DE@200643|Bacteroidia,4AWDW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Membrane 1.0 - 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_02373 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 273852 149381 690812 0 341263 214367 0 0 0 209705 358170 296751 0 325896 0 279535 544454 0 0 337137 0 393773 126113 257656 0 182778 351483 0 0 0 0 364921 0 303360 0 0 0 0 706629 637311 564334 569894 510391 554206 529291 654732 633517 772479 489968 1045502 0 725408 699832 606956 575224 187827 751372 464505 0 594088 310496 431461 528200 632446 661924 436295 489672 495696 0 640142 544674 590878 470772 771719 761445 653097 622340 641763 857167 720919 788480 966465 811000 673610 803500 857609 1262517 689807 0 848669 899803 561896 619767 1098218 693505 728100 0 702498 772536 656027 863605 727693 646629 1000387 740476 799556 0 256373 431285 696913 671989 819502 679567 711377 304519 277276 0 303743 369377 296955 0 203904 332630 0 303714 201803 0 0 312233 442096 172713 199932 301149 0 0 204232 0 180902 306410 272545 0 751725 290256 0 0 335246 348982 346973 0 510286 305376 0 0 205716 0 333978 429184 486792 0 445875 270570 324186 1064830 553745 0 0 0 648447 0 454744 408304 594938 0 408507 0 300348 338754 0 0 639200 528036 504402 0 473241 0 351127 669715 111373 266046 512459 +(Gln->pyro-Glu)QKELQDMMQR MGYG000000196_00111;MGYG000000013_00131;MGYG000002549_03516;MGYG000000029_03029;MGYG000003351_03212;MGYG000000054_01820;MGYG000001378_02728 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00111 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 0 0 317614 706522 0 0 932599 1113761 841290 0 1194210 0 0 746005 0 631669 0 0 409946 0 1183145 0 0 0 0 756213 0 0 0 0 0 0 0 0 0 900163 333671 407958 639669 0 765459 641380 0 0 595011 677570 228514 0 1073358 0 0 782769 0 668098 0 0 543277 0 584849 0 0 0 0 437243 0 0 0 0 0 0 449787 0 0 722754 471247 465756 425850 0 533740 0 0 0 521192 310764 576049 0 244063 0 0 0 0 0 0 0 386222 0 304727 0 0 0 0 0 0 0 0 0 0 0 221763 0 0 487744 473019 655181 0 0 571798 0 0 0 0 0 0 0 339723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 574481 0 0 0 0 0 0 0 0 0 0 0 260545 0 0 303738 371159 0 0 0 0 0 0 457682 0 0 324689 0 0 0 0 282837 0 0 0 0 0 0 272518 0 0 0 0 0 0 140930 0 0 0 334688 407261 +(Gln->pyro-Glu)QKELQELNEK MGYG000000243_03119 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03119 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 0 0 1675811 0 0 0 0 0 0 0 761767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1848866 0 0 0 0 1992865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 751901 0 0 0 0 0 +(Gln->pyro-Glu)QKELQELQEK MGYG000002478_01528;MGYG000002560_00092;MGYG000004797_03114 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01528 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 0 0 0 0 1002696 0 0 0 0 0 416735 294496 1520986 0 0 1417024 0 368541 0 0 0 0 313501 0 0 0 0 400713 0 0 0 867722 761918 0 0 0 556130 614024 602877 0 672684 0 791977 0 0 0 0 0 680043 433555 1370890 0 0 1200963 0 0 0 0 0 0 0 0 0 533628 0 486246 0 675025 0 425193 767567 0 0 0 876903 541057 0 0 572625 0 1026099 0 0 0 0 0 348608 0 1258197 0 0 803326 0 705702 0 0 0 0 815103 0 0 297770 0 0 0 329585 0 0 0 0 0 0 616065 519392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520084 0 706774 0 1350171 0 0 0 0 0 490169 538005 1298275 0 0 1077114 0 1027049 0 0 0 0 800140 0 0 696085 0 476794 0 988679 0 803595 303619 0 0 0 1059047 893790 +(Gln->pyro-Glu)QKEVLEMPNLIEVQKDSYK MGYG000004271_02226;MGYG000000271_03641 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 - 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_02226 0.5 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03043:rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKFDMEDR MGYG000002619_02235;MGYG000002223_00611;MGYG000001255_01110;MGYG000001300_00291;MGYG000002610_00221;MGYG000003166_01338;MGYG000000195_01569;MGYG000003291_01730;MGYG000002651_00003;MGYG000000022_01320 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002619_02235 0.1 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 2561677 2907083 4499904 3230745 903956 2600550 1568219 1601009 2448233 2845471 1832854 1654017 4653574 3738371 2828500 3203934 2998217 924398 6259231 3894597 1308504 2648809 741548 2270959 3006088 3133710 2698509 983802 0 1471454 2216310 2085944 4191788 4537331 1745160 1923482 2150722 4036450 4276029 5192475 5475032 3617608 3633886 4767203 5143866 2065215 4156453 939799 2965857 4207397 3809493 4525126 4318007 2817379 4133318 1192193 6467561 4254830 2143373 3945473 1311103 4440314 5700789 5160943 3889506 1601031 698992 3372021 5758047 4857921 4648439 4251487 1574375 3863301 4249986 5009985 730144 1283289 1081558 1072728 1118569 640423 1135081 901346 1080988 575239 1570543 688876 1318515 903420 904576 1066237 596140 1540644 891681 744113 590124 442682 1753259 803659 880257 801852 851846 1818645 559085 866922 939371 1395913 861581 1251728 499902 1146232 980631 997275 2481114 3755274 5497379 2694893 3854794 5066207 4512676 1565963 3801852 3870376 3919923 5195110 3852831 3098560 3277280 3855106 3188670 2072982 5509905 3451065 3580163 3519582 2124202 2778934 4111580 3438095 3432852 2516183 2023504 3973486 4878717 3396363 5476989 4333277 578992 2219549 3417993 6732702 0 0 535714 0 0 149777 0 0 0 219053 0 0 120411 0 201738 147282 0 1773252 0 0 0 0 1798402 0 0 0 0 1719926 0 0 200975 227656 529891 0 0 0 0 616457 +(Gln->pyro-Glu)QKFGHVK MGYG000000243_03119 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03119 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 0 0 2518121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3323431 0 0 0 0 3390638 0 0 204004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322984 0 0 96019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95442 +(Gln->pyro-Glu)QKIAPIAGAK MGYG000000271_02100;MGYG000002517_00544;MGYG000000245_02023 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02100 0.3333333333333333 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 268270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1508633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKIEVTIPAK MGYG000002492_02675 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,27JIP@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_02675 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K05808:hpf; ribosome hibernation promoting factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480484 0 1524109 0 1753602 0 0 0 0 0 0 0 0 0 0 0 0 1922581 356577 514060 0 0 1176318 0 0 558957 0 1802142 0 0 0 0 1600815 0 0 0 570934 1871209 972948 0 3998342 0 1966981 0 0 0 0 0 0 0 0 0 0 0 0 691922 978018 928035 0 0 1044063 0 0 1165975 0 1599673 0 0 0 0 3507092 0 0 0 1120115 3198648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKIEVTIPMK MGYG000002528_01889 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,269H5@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01889 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K05808:hpf; ribosome hibernation promoting factor 1.0 none 1.0 0 348539 368279 0 0 579402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 491041 0 370729 0 0 0 0 0 0 0 0 204210 0 0 0 0 301987 0 384794 201955 0 0 432915 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104439 0 501306 0 0 0 0 0 0 0 0 586325 0 0 0 0 143277 0 1706786 672499 0 0 835031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1979417 0 590393 0 0 0 0 0 0 0 0 770889 0 0 0 0 793459 0 229751 242045 0 0 210859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188662 0 0 0 0 0 0 0 0 149723 0 0 0 0 233427 0 258719 148628 0 0 699030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293697 0 142501 0 0 0 0 0 0 0 0 342241 0 0 0 0 707158 +(Gln->pyro-Glu)QKIEVTIPVK MGYG000000484_01496;MGYG000004733_00624;MGYG000000087_01289;MGYG000000002_00056;MGYG000000562_01970;MGYG000000038_01170;MGYG000004317_01434;MGYG000000205_02153;MGYG000000216_02638;MGYG000004869_04439;MGYG000001374_02466;MGYG000004519_00241;MGYG000002279_00296;MGYG000002835_00316;MGYG000004263_00951;MGYG000002992_01592;MGYG000000135_03575;MGYG000000249_00881;MGYG000000179_05419;MGYG000001367_04105;MGYG000003984_01028;MGYG000003684_03074;MGYG000004039_00581;MGYG000003012_02718;MGYG000004735_02698;MGYG000001607_01765;MGYG000002393_01024;MGYG000004842_00271;MGYG000004691_01360;MGYG000001571_02605;MGYG000000172_03322;MGYG000000806_01841;MGYG000002234_01596;MGYG000001027_00049;MGYG000000301_01176;MGYG000002945_01017;MGYG000000242_01723;MGYG000000201_01390;MGYG000000417_00332;MGYG000000140_00197;MGYG000000127_00990;MGYG000000359_01150;MGYG000002445_02284;MGYG000004689_01666;MGYG000001689_00254;MGYG000000251_02361;MGYG000001303_00122;MGYG000002946_03244;MGYG000003821_01882;MGYG000001338_01148;MGYG000000233_03002;MGYG000000278_00992;MGYG000000325_01136;MGYG000000200_01813;MGYG000000164_02141;MGYG000000187_02100;MGYG000000217_01334;MGYG000003783_01852;MGYG000000198_05420;MGYG000004087_02933;MGYG000000133_02532;MGYG000000050_01293;MGYG000001199_01379;MGYG000000312_00823;MGYG000000142_00063;MGYG000002212_00396;MGYG000003335_01038;MGYG000001531_03045;MGYG000001698_02999;MGYG000000031_00635;MGYG000002202_00135;MGYG000004799_00574;MGYG000001315_00409;MGYG000001065_00847;MGYG000004630_00387;MGYG000000139_02374;MGYG000001617_02330 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3XZRY@572511|Blautia 0.2727272727272727 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000484_01496 0.012987012987012988 - - - - 1.0 1.0 1.0 1.0 - 1.0 K05808:hpf; ribosome hibernation promoting factor 1.0 none 1.0 1429353 1582510 1034911 934725 1563860 1733117 954488 1686116 1143752 1525099 1518201 1366282 2006496 1451801 2165101 1641909 1617690 2798705 1224248 1512015 1541140 1814782 2467718 1157316 1601243 1213646 1305490 2916404 1631774 1538642 988977 1555015 1084381 1391696 1316528 1303510 1160085 1133250 1708431 2440319 1494448 1799465 1251195 0 1484724 1982217 1484459 1517945 1097170 1522666 1661848 0 1205988 1128691 1648583 1648174 1259996 1475383 1319377 671292 1117166 1237711 1685270 1413216 1575297 1414424 1490525 1421354 2750723 1461476 1227329 1898322 1909685 1521810 1409549 1342299 1872066 2350482 1730896 1334858 1441739 1733577 1513999 2281043 1568071 1864972 1274699 2119355 1976391 1745883 1996663 1915532 1626052 1901292 1764144 1865395 2002476 2114457 2254194 1444605 1736546 2040647 2184129 2671170 1550050 2144329 1700159 1885374 1813117 2284976 2134971 1592297 1800815 1547005 835080 1837840 1115949 693739 1423593 866992 680613 639303 736932 894533 1179506 955229 1327466 1037075 685388 1266548 1089022 774491 643851 752623 870900 813924 705281 1136412 638426 717491 893258 965320 1117347 971344 1479118 1309757 1224993 635819 888226 667243 782943 1645313 1821524 2188652 2488187 2315658 973824 1685104 2592286 1676541 1374028 2100666 1631421 1704943 1691359 2058727 1983067 2451605 1681610 1346955 2209140 833081 2224568 1958486 1787815 1361391 1767007 0 1650621 2154354 2033424 953403 2146946 2204590 3632013 2146263 1535833 1524831 1077597 1968180 +(Gln->pyro-Glu)QKIEVTIPVKGNIIR MGYG000000301_01176;MGYG000002945_01017;MGYG000000201_01390;MGYG000000417_00332;MGYG000004733_00624;MGYG000000002_00056;MGYG000000142_00063;MGYG000002835_00316;MGYG000000562_01970;MGYG000004317_01434;MGYG000002212_00396;MGYG000000249_00881;MGYG000000251_02361;MGYG000000031_00635;MGYG000003821_01882;MGYG000001338_01148;MGYG000000216_02638;MGYG000004735_02698;MGYG000001315_00409;MGYG000000200_01813;MGYG000000187_02100;MGYG000000806_01841;MGYG000002234_01596;MGYG000000133_02532 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3XZRY@572511|Blautia 0.625 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_01176 0.041666666666666664 - - - - 1.0 1.0 1.0 1.0 - 1.0 K05808:hpf; ribosome hibernation promoting factor 1.0 none 1.0 0 1251349 2069708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 455147 1296687 1231575 0 0 0 0 537373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 817030 518487 0 0 0 0 0 0 0 1973983 568062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 867840 1103047 982526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 847502 1150236 1846256 0 0 0 0 935382 +(Gln->pyro-Glu)QKITEDNVQAIALGTDKK MGYG000000243_01847 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01847 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03072:secD; preprotein translocase subunit SecD|K12257:secDF; SecD/SecF fusion protein 1.0 none 1.0 0 0 542950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581605 0 0 0 0 261991 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKLESQISTLYGGR MGYG000002506_02820;MGYG000002534_00540;MGYG000002494_01794;MGYG000002515_03062;MGYG000002477_04931 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0465@1|root,COG0465@2|Bacteria,1MU6J@1224|Proteobacteria,1RME8@1236|Gammaproteobacteria,41F7V@629|Yersinia 0.6 1236|Gammaproteobacteria 1.0 O 1.0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins 1.0 ftsH 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 1.0 - 1.0 ko:K03798 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000,ko01002,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,FtsH_ext,Peptidase_M41 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02820 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03798:ftsH, hflB; cell division protease FtsH [EC:3.4.24.-] 1.0 none 1.0 0 0 530079 0 0 0 0 0 0 409658 0 0 0 0 0 0 0 0 0 0 0 455306 0 922477 0 0 0 0 0 0 0 0 949449 0 0 0 0 516182 0 0 763228 0 0 872704 530640 0 626276 581209 0 0 0 0 0 0 0 0 544431 0 0 1001693 0 696889 0 0 0 0 905159 0 0 0 532433 0 0 0 0 544317 0 0 0 0 0 345277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 198685 0 0 238384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKLMMDASTSR MGYG000000003_00816;MGYG000003279_01723 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,2FMVP@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG10142 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Porin_2,SH3_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_00816 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 149259 0 0 0 0 0 0 0 0 0 588873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKLPSNN(Deamidated)GGFK MGYG000000243_02784;MGYG000001780_04138;MGYG000001345_00972;MGYG000002478_03897;MGYG000000044_00884;MGYG000002549_00555 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1830@1|root,COG1830@2|Bacteria,4NEUM@976|Bacteroidetes,2FKZ7@200643|Bacteroidia,4APQV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes 1.0 fbaB 1.0 - 1.0 4.1.2.13 1.0 ko:K11645 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DeoC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02784 0.16666666666666666 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K11645:fbaB; fructose-bisphosphate aldolase, class I [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1002603 0 0 0 0 1304754 0 0 0 0 1552347 0 0 0 0 1630204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 487499 0 0 0 0 579981 0 0 0 0 0 0 0 0 0 776293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 831239 0 0 0 0 1807235 0 0 0 0 1797298 0 0 0 0 1694936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660262 0 0 0 0 541607 0 0 0 0 0 0 0 0 0 2019717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 420124 0 0 0 0 910026 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKLVSADEAVK MGYG000002517_02708;MGYG000000271_00943;MGYG000000245_03528;MGYG000004414_01832;MGYG000004271_01186 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Acetyl-CoA hydrolase transferase 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02708 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKPLRVILN(Deamidated)GLGK MGYG000000245_00061;MGYG000000251_02115;MGYG000000312_02568;MGYG000000262_01832;MGYG000000127_05084;MGYG000000404_00348;MGYG000003425_04615;MGYG000001606_02183;MGYG000000187_00466;MGYG000002528_00119;MGYG000000198_05683 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.36363636363636365 186801|Clostridia 0.8181818181818182 S 0.8181818181818182 Psort location Cytoplasmic, score 8.87 0.36363636363636365 - 0.8181818181818182 - 1.0 - 0.8181818181818182 - 0.8181818181818182 - 0.8181818181818182 - 0.8181818181818182 - 0.8181818181818182 - 0.8181818181818182 - 0.8181818181818182 - 1.0 - 1.0 - 1.0 GGGtGRT 0.8181818181818182 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000245_00061 0.09090909090909091 - - - - 0.8181818181818182 0.8181818181818182 0.8181818181818182 0.8181818181818182 - 0.8181818181818182 - 0.8181818181818182 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKPVFVEDAK MGYG000002494_00281 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation 1.0 metE 1.0 - 1.0 2.1.1.14 1.0 ko:K00549 1.0 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 1.0 M00017 1.0 R04405,R09365 1.0 RC00035,RC00113,RC01241 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iJN746.PP_2698 1.0 Meth_synt_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00281 1.0 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. tetrahydropteroylglutamate-homocysteine transmethylase. Requires phosphate.-!-The enzyme from Escherichia coli also requires a reducing system.-!-Unlike EC 2.1.1.13 this enzyme does not contain cobalamin. 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Selenocompound metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00549:metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 855314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 615500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKPWGQK MGYG000002791_00401 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__|m__MGYG000002791 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,36EGU@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002791_00401 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1158225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 593972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 543799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 999952 0 0 +(Gln->pyro-Glu)QKQAETGIK MGYG000002281_00379;MGYG000001789_01205;MGYG000001313_01603;MGYG000001337_02813;MGYG000004763_01996;MGYG000002478_04391;MGYG000000224_02138;MGYG000004797_00652;MGYG000000196_04607;MGYG000004876_02961;MGYG000001787_00293;MGYG000001346_00290 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,2FN9P@200643|Bacteroidia,4AN2N@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 xylA 1.0 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 1.0 5.3.1.5 1.0 ko:K01805 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 - 1.0 R00878,R01432 1.0 RC00376,RC00516 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_00379 0.08333333333333333 xylose isomerase. D-xylose ketol-isomerase. Contains two divalent metal ions, preferably magnesium, located at different metal-binding sites within the active site.-!-The enzyme catalyzes the interconversion of aldose and ketose sugars with broad substrate specificity.-!-The enzyme binds the closed form of its sugar substrate (in the case of xylose and glucose, only the alpha anomer) and catalyzes ring opening to generate a form of open-chain conformation that is coordinated to one of the metal sites.-!-Isomerization proceeds via a hydride-shift mechanism. alpha-D-xylose = alpha-D-xylulofuranose. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K01805:xylA; xylose isomerase [EC:5.3.1.5] 1.0 none 1.0 655546 793219 1207015 959492 1060824 0 1079099 1109939 0 1555406 1104980 1305543 0 1162747 982704 966206 1075647 424281 1301677 0 0 0 330582 0 0 1338401 0 426582 915008 1280677 0 1121553 730747 0 1221099 912394 784821 709623 698696 719739 500184 693707 906316 0 436974 755507 0 986810 947431 845956 0 698637 783505 568638 517862 682698 813844 0 0 0 719428 0 0 661063 0 807271 708842 590277 0 937696 547628 0 725430 346419 614136 599962 796999 807840 888109 925157 898774 0 897663 1128335 0 1357799 784073 1014990 0 892241 555068 630700 803931 2045946 971193 0 0 0 1215090 0 0 1000789 0 1500513 855070 1127347 0 922368 732619 0 875717 1268506 758473 593608 0 290143 363620 276215 249089 0 0 430501 0 391009 225193 520919 0 352876 0 0 526058 582060 862355 0 0 0 282920 0 0 498957 0 576081 335936 478114 0 337732 549527 0 0 0 454821 0 422869 332520 328296 420711 946762 0 479059 620274 0 564165 717461 592776 0 455576 431875 408254 648894 319108 467221 0 0 0 0 0 0 813488 0 0 629260 645502 0 481457 0 0 1091299 354215 702643 642546 +(Gln->pyro-Glu)QKQEETGIK MGYG000003681_01596 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,2FN9P@200643|Bacteroidia,4AN2N@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 xylA 1.0 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 1.0 5.3.1.5 1.0 ko:K01805 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 - 1.0 R00878,R01432 1.0 RC00376,RC00516 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_01596 1.0 xylose isomerase. D-xylose ketol-isomerase. Contains two divalent metal ions, preferably magnesium, located at different metal-binding sites within the active site.-!-The enzyme catalyzes the interconversion of aldose and ketose sugars with broad substrate specificity.-!-The enzyme binds the closed form of its sugar substrate (in the case of xylose and glucose, only the alpha anomer) and catalyzes ring opening to generate a form of open-chain conformation that is coordinated to one of the metal sites.-!-Isomerization proceeds via a hydride-shift mechanism. alpha-D-xylose = alpha-D-xylulofuranose. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K01805:xylA; xylose isomerase [EC:5.3.1.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2041135 0 0 0 0 1747789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 419182 0 0 0 0 361895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312403 0 0 0 0 292654 0 0 0 0 525471 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKQEFQTK MGYG000001313_00977;MGYG000004748_00249 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,2FPTR@200643|Bacteroidia,4AMZ6@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 - 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_00977 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1163971 0 0 0 0 651237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303978 0 0 0 0 226103 0 0 0 0 216187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1069800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKQPVDYVNPLMGTDSK MGYG000000196_01625;MGYG000001378_03102;MGYG000001345_01444;MGYG000002281_00094 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FMXD@200643|Bacteroidia,4APMR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Glycosyl hydrolase family 92 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_92 1.0 3.2.1.113|3.2.1.- 1.0 GH92 1.0 GH92 1.0 GH92 0.75 MGYG000000196_01625 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 624348 0 0 877851 0 655340 882020 898817 0 721165 413933 0 0 694832 0 0 0 0 697864 0 788008 466852 0 793238 0 819658 774109 0 0 0 0 0 0 0 0 855595 1142878 0 443174 0 0 1070011 0 818956 569717 748547 0 686417 703500 0 0 820791 0 0 0 0 693462 0 642371 706626 0 552218 0 639830 655737 0 0 0 0 0 0 0 0 581116 741424 0 0 0 0 0 0 0 574608 0 0 0 322716 0 0 0 0 0 0 0 591551 0 0 0 0 374999 0 0 0 0 0 0 0 0 0 0 0 615133 0 0 395325 0 0 334731 0 520478 405357 0 0 221959 0 0 0 0 0 0 0 0 425753 0 0 353667 0 392806 0 0 367698 0 0 0 0 0 0 0 0 389646 381859 0 0 0 0 0 0 621969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 537106 0 0 0 0 0 0 0 0 0 0 0 348431 0 0 +(Gln->pyro-Glu)QKTDIPATVK MGYG000001300_02212 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WGQK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02212 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 426122 510537 724070 570316 0 391585 110159 214346 309082 0 242699 0 0 582807 0 0 532897 0 612123 606003 0 617717 264715 0 0 443223 521013 153401 0 196554 0 265602 580572 653883 0 255578 189279 716564 1966799 1309249 1595100 1593461 890356 1158549 1972910 628290 2240825 0 1067632 1255303 0 1950052 0 0 1403474 567230 1894866 1598525 0 761318 696267 1178041 0 1459568 1348997 834081 0 1288221 1413739 859010 1374217 1695052 0 1475115 1767226 1272566 0 169920 0 0 254098 0 0 0 0 0 262584 125837 0 0 0 0 0 704167 0 231652 0 157911 482814 0 0 0 0 460672 0 0 0 264836 138021 334309 0 0 0 143300 781372 675908 1138036 718560 762734 943250 867739 335171 568492 0 773924 1002850 0 776077 0 0 635918 318586 795918 627608 0 1170053 0 817265 0 652486 957329 514157 0 1010659 867625 709163 967660 789214 0 916021 666072 1113162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1245424 0 0 0 0 1186995 0 0 0 0 1101944 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKTGLMIDAYFSGTK MGYG000002528_01426 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01426 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKTGLVIDAYFSGTK MGYG000001617_02316;MGYG000002517_00259;MGYG000001619_01501;MGYG000004630_02409;MGYG000000389_02030 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 0.6 186801|Clostridia 1.0 C 0.6 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001617_02316 0.2 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502715 646591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1733432 1643958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1559767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2751494 1978669 0 0 0 +(Gln->pyro-Glu)QKVDLNTFSDEEVLR MGYG000002494_02481;MGYG000002500_00412;MGYG000002534_04618;MGYG000002477_00983 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0085@1|root,COG0222@1|root,KOG0214@2759|Eukaryota,KOG1715@2759|Eukaryota,39VWS@33154|Opisthokonta,3BM6Z@33208|Metazoa,3DDNE@33213|Bilateria 1.0 33208|Metazoa 1.0 K 1.0 DNA-directed 5'-3' RNA polymerase activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7,Ribosomal_L10,Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02481 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1217271 0 0 0 1728107 0 0 0 0 0 0 0 0 0 0 0 0 1040801 0 0 1736984 0 1720865 1087619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKVEVTIPMKGSYIR MGYG000000271_01273;MGYG000004271_02465 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_01273 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K05808:hpf; ribosome hibernation promoting factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKVMLEGILDISK MGYG000002517_01337 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,25BET@186801|Clostridia 1.0 186801|Clostridia 1.0 NT 1.0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). 1.0 - 1.0 - 1.0 - 1.0 ko:K03406 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 MCPsignal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01337 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03406:mcp; methyl-accepting chemotaxis protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKVTDVEGK MGYG000002515_03209;MGYG000002506_02967 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,1RNSZ@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000002515_03209 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 607116 0 0 1022288 546734 683410 408651 817473 0 0 0 0 1189403 0 0 0 0 888570 0 1159071 0 1071780 889861 0 0 0 0 0 0 0 494776 818204 0 0 0 593722 0 0 0 0 0 371261 0 262531 0 268535 0 0 0 0 0 0 0 0 0 0 0 233233 0 220908 0 0 0 0 0 0 0 0 0 227518 0 0 0 0 0 0 1349289 0 0 1434070 683561 1089828 1321842 984579 0 0 0 0 941386 0 0 0 0 1104328 0 1433030 0 1338945 1206584 0 0 0 0 0 0 0 867910 918919 0 0 0 1044760 0 0 1041937 0 0 1514113 1078848 1549681 817878 1771926 0 0 0 0 977049 0 0 0 0 0 0 1158468 0 0 946401 0 0 0 0 0 0 0 0 1407940 0 0 0 0 0 0 0 0 0 105183 0 0 115266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKVVAAEVENVK MGYG000000271_01229;MGYG000002517_01330 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 'glutamate synthase 1.0 gltA 1.0 - 1.0 1.4.1.13,1.4.1.14 1.0 ko:K00266 1.0 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 1.0 - 1.0 R00093,R00114,R00248 1.0 RC00006,RC00010,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,NAD_binding_8,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_01229 0.5 glutamate synthase (NADPH). | glutamate synthase (NADH). NADPH-glutamate synthase. | NADH-glutamate synthase. The reaction takes place in the opposite direction.-!-The protein is composed of two subunits, alpha and beta.-!-The alpha subunit is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.4).-!-The beta subunit transfers electrons from the cosubstrate.-!-The NH3 is channeled through a 31 A channel in the active protein.-!-In the absence of the beta subunit, coupling between the two domains of the alpha subunit is compromised and some ammonium can be produced.-!-In the intact alphabeta complex, ammonia production only takes place as part of the overall reaction.-!-Formerly EC 2.6.1.53. | A flavoprotein (FMN).-!-The reaction takes place in the direction of L-glutamate production.-!-The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2). 2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH. | 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K00266:gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1316802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 917146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKVYSVEAAK MGYG000000164_00686;MGYG000000271_02102;MGYG000002517_00542 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_00686 0.3333333333333333 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1973887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QKYVKPLATGEK MGYG000002517_00542;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00542 0.5 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87037 0 0 217184 0 0 0 0 0 0 156097 94592 63366 0 0 99219 0 132854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102099 0 0 131110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 807500 0 0 0 0 0 0 994461 921225 624838 0 0 745164 0 739714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 580431 0 0 736915 0 653351 +(Gln->pyro-Glu)QLAAENFGESVEETPASSTAR MGYG000002494_03341 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1080@1|root,COG1925@1|root,COG3412@1|root,COG1080@2|Bacteria,COG1925@2|Bacteria,COG3412@2|Bacteria,1MUT8@1224|Proteobacteria,1RRCZ@1236|Gammaproteobacteria,3WVVD@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 PEP-utilising enzyme, N-terminal 1.0 dhaM 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006476,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033554,GO:0033558,GO:0034983,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0047324,GO:0050896,GO:0051716,GO:0071704,GO:0098732,GO:0140096,GO:1901564 1.0 2.7.1.121 1.0 ko:K05881 1.0 ko00561,map00561 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000,ko02000 1.0 - 1.0 - 1.0 iECs_1301.ECs1703,iSF_1195.SF1201,iS_1188.S1285,iUTI89_1310.UTI89_C1391,iZ_1308.Z1969 1.0 EIIA-man,PEP-utilisers_N,PEP-utilizers,PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03341 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism 1.0 K05881:dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 696755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 684635 0 601686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLAAYGHMGR MGYG000001300_00585;MGYG000000573_01026;MGYG000002059_01607;MGYG000000084_01929 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3WGI3@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme 1.0 metK 1.0 - 1.0 2.5.1.6 1.0 ko:K00789 1.0 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 1.0 M00034,M00035,M00368,M00609 1.0 R00177,R04771 1.0 RC00021,RC01211 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N,YgbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00585 0.25 methionine adenosyltransferase. S-adenosylmethionine synthetase. Formerly EC 2.4.2.13. ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L- methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00789:metK, MAT; S-adenosylmethionine synthetase [EC:2.5.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 329642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 510499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLADKFGFEK MGYG000001761_01355;MGYG000000084_00730;MGYG000002148_01347;MGYG000004732_00468;MGYG000000573_00769 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WHKM@541000|Ruminococcaceae 0.8 186801|Clostridia 1.0 G 1.0 Kinase, PfkB family 0.8 - 1.0 - 1.0 2.7.1.45 1.0 ko:K00874 1.0 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 1.0 M00061,M00308,M00631 1.0 R01541 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001761_01355 0.2 2-dehydro-3-deoxygluconokinase. KDG kinase. The enzyme shows no activity with 2-dehydro-3-deoxy-D-galactonate. cf. EC 2.7.1.178. 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D- gluconate + ADP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00874:kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6775867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3720957 0 0 0 0 5115549 0 0 0 0 3396477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3200184 0 0 0 0 2904890 0 0 0 0 4477022 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLADKFHFEK MGYG000002641_01227;MGYG000002272_02009;MGYG000002619_01740;MGYG000004679_00158;MGYG000000022_00356;MGYG000000195_01974;MGYG000002274_00782;MGYG000002610_02119;MGYG000003166_00504;MGYG000003921_02029;MGYG000000039_01372;MGYG000002545_01709;MGYG000001255_00803;MGYG000002224_01974 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WHKM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Kinase, PfkB family 1.0 - 1.0 - 1.0 2.7.1.45 1.0 ko:K00874 1.0 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 1.0 M00061,M00308,M00631 1.0 R01541 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002641_01227 0.07142857142857142 2-dehydro-3-deoxygluconokinase. KDG kinase. The enzyme shows no activity with 2-dehydro-3-deoxy-D-galactonate. cf. EC 2.7.1.178. 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D- gluconate + ADP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00874:kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] 1.0 none 1.0 616150 674312 715916 686452 771278 810174 838837 674516 752456 903752 599807 614865 646621 844791 881883 625582 834827 2631783 749557 682900 694433 662305 2231486 791918 643312 810913 714006 2244710 741559 789616 722837 631348 706095 915695 866847 743424 626105 600906 763433 426101 624946 757181 509281 619619 665847 755185 818931 530636 570271 623061 616726 729910 727802 548044 723867 2367022 799190 875906 388613 543745 2951467 512328 739271 821702 740187 2578168 306012 634690 456067 583689 521367 768513 559767 532622 777549 688424 643587 721207 734146 885666 864261 724379 741455 909391 746660 810684 686715 737628 645541 745410 659357 742644 605836 2570302 526798 543344 614904 587251 2543966 955826 714627 740424 674833 3205853 769856 711040 792184 785126 517123 713143 819235 638873 809030 806258 778640 1009650 1038732 946729 728968 1288731 1198623 756170 1117002 1012935 1085479 987443 1294634 1157336 930456 730892 993667 2260522 1347962 967443 1113747 1060259 4092235 521372 1356657 1189566 1003633 2666217 697224 1218475 1020067 1042337 1172353 1564952 1208044 1132037 1057541 953494 542918 428420 534634 613134 725414 615316 579611 635319 588070 587566 537605 497236 495429 547914 509510 480254 615229 2633381 471504 533793 524676 648463 2797189 500747 430807 552791 519787 3321620 617617 723828 610290 552433 431746 713665 1122495 571311 613875 720579 +(Gln->pyro-Glu)QLADYLEITDVLDKFPSK MGYG000000251_00368;MGYG000001456.1_01658;MGYG000000245_01185 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 V 1.0 Psort location CytoplasmicMembrane, score 1.0 - 1.0 - 1.0 - 1.0 ko:K02003 1.0 - 1.0 M00258 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1 1.0 - 1.0 - 1.0 ABC_tran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_00368 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02003:ABC.CD.A; putative ABC transport system ATP-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLAELPR MGYG000002494_03637 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0141@1|root,COG0141@2|Bacteria,1MUUF@1224|Proteobacteria,1RMZD@1236|Gammaproteobacteria,3WX04@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine 1.0 hisD 1.0 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.1.1.23 1.0 ko:K00013 1.0 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 1.0 M00026 1.0 R01158,R01163,R03012 1.0 RC00099,RC00242,RC00463 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECUMN_1333.ECUMN_2362,iG2583_1286.G2583_2541,iUTI89_1310.UTI89_C2293,ic_1306.c2547 1.0 Aminotran_1_2,Histidinol_dh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03637 1.0 histidinol dehydrogenase. - Also oxidizes L-histidinal.-!-The Neurospora enzyme also catalyzes the reactions of EC 3.5.4.19 and EC 3.6.1.31. H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH. 1.0 1.0 1.0 1.0 Histidine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00013:hisD; histidinol dehydrogenase [EC:1.1.1.23] 1.0 none 1.0 0 0 0 0 0 80558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410895 0 337860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLAEQTKNSTEQITR MGYG000004271_01025 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,25BET@186801|Clostridia 1.0 186801|Clostridia 1.0 NT 1.0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). 1.0 - 1.0 - 1.0 - 1.0 ko:K03406 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 MCPsignal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01025 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03406:mcp; methyl-accepting chemotaxis protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLAGMRGLIANTSGTTIEIPIR MGYG000001756_02184 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__UBA1394|s__UBA1394 sp900538575|m__MGYG000001756 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000001756_02184 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1422125 0 88881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLAMHVAASKPEFVKPEDVSAEVVEK MGYG000002494_03067 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0264@1|root,COG0264@2|Bacteria,1MUS2@1224|Proteobacteria,1RPBJ@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03067 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 893249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 620108 1080154 0 868968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLANKR MGYG000000301_00161;MGYG000002845_00979;MGYG000004733_00969;MGYG000001619_00833;MGYG000001367_00350;MGYG000002966_02574;MGYG000000398_00951;MGYG000000179_04599;MGYG000004735_01600;MGYG000000233_02344;MGYG000000198_04888;MGYG000001315_01337;MGYG000000133_00046;MGYG000001379_01346;MGYG000000262_00147 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia 0.4 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_00161 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 434294 375742 594668 74384 0 1005449 334723 250091 701485 537486 860669 0 0 516708 633655 0 559833 0 0 0 376326 1698900 0 545963 0 508064 655614 0 202669 0 0 471540 853499 544104 580850 0 610835 671703 333260 282748 302005 298326 0 530792 284424 288491 249745 412248 80948 0 0 231666 389423 0 396194 0 0 0 473250 458344 0 425868 0 306760 384339 0 386939 0 0 0 238584 254012 238195 0 275668 0 344719 467629 795702 495237 0 588540 285799 538966 403246 490785 414029 0 0 462079 660713 0 490119 0 0 0 507841 1071084 0 643269 0 453140 565788 0 462008 0 0 548629 678141 710656 485366 0 487734 614135 484450 736044 289524 647753 0 523405 743040 452905 439972 570946 411650 0 0 412093 375792 0 579404 0 0 0 0 646749 0 467407 0 79726 461580 0 411863 0 0 1043849 299071 528513 612868 0 426586 284537 1590472 1746643 1883547 4001945 0 1191406 2669611 1128278 1336350 2472663 4520242 0 0 5226199 2408885 0 1246270 0 0 0 1874388 1682658 0 2283787 0 1802888 3236670 0 3672019 0 0 1800166 6396292 2532203 2313523 0 2324903 1853091 +(Gln->pyro-Glu)QLANSSIQGDQLKK MGYG000002834_00586;MGYG000003697_00203 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,2FNI1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002834_00586 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 696292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLAYEIQK MGYG000002772_02524;MGYG000002528_01544;MGYG000000028_01782 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds together with S18 to 16S ribosomal RNA 1.0 rpsF 1.0 - 1.0 - 1.0 ko:K02990 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002772_02524 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02990:RP-S6, MRPS6, rpsF; small subunit ribosomal protein S6 1.0 none 1.0 0 154642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 973949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLC(Carbamidomethyl)DIGKR MGYG000000031_02924;MGYG000000142_01607 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3XZRB@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 4.1.2.17 1.0 ko:K01628 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R02262 1.0 RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_02924 0.5 L-fuculose-phosphate aldolase. L-fuculose-1-phosphate lactaldehyde-lyase. - L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01628:fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLC(Carbamidomethyl)HNC(Carbamidomethyl)VAK MGYG000001300_00243;MGYG000002641_00107;MGYG000002040_01442;MGYG000002223_01488;MGYG000002274_02567 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00243 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 398815 0 472319 346797 0 297510 240072 0 272163 0 0 0 148113 0 0 0 0 0 421565 0 0 288840 0 370778 0 489009 261377 0 0 235496 241831 0 233343 0 0 0 0 575777 1204837 1030242 1164390 1099784 718658 921507 1043882 0 1372932 0 0 0 711241 0 0 0 910664 0 1164170 0 0 611239 0 831559 0 873381 786692 0 0 730913 855029 0 1032960 0 0 0 970778 789444 148579 0 141013 159541 0 0 135137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307566 0 0 0 480423 209656 0 0 357560 334084 0 0 0 0 0 0 0 434182 248355 838699 441645 556128 629878 909213 0 565334 0 0 0 736801 0 0 0 428671 0 535602 0 0 554904 0 0 0 793036 601896 0 0 696789 537730 0 758887 0 0 0 565757 697043 0 0 0 271656 120681 0 0 0 234715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 514534 0 0 0 0 0 0 255685 0 +(Gln->pyro-Glu)QLC(Carbamidomethyl)LDRDPHGNVQVSLIETEK MGYG000003697_01061;MGYG000001630_00093;MGYG000002080_02441;MGYG000002960_01607;MGYG000002293_01291 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia 0.8 976|Bacteroidetes 1.0 H 0.8 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 MGYG000003697_01061 0.2 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 758656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1008728 0 0 0 0 0 0 0 0 0 379309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 864564 0 0 0 0 0 0 0 0 0 0 0 881352 0 0 0 848048 1710831 583626 0 0 0 391675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLDAYVAGLK MGYG000000251_00545 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter saccharivorans|m__MGYG000000251 1.0 COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,24AWQ@186801|Clostridia,27KF0@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Domain of unknown function (DUF3502) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF3502,SBP_bac_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_00545 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 329901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLDDAYLQAR MGYG000002494_03341 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1080@1|root,COG1925@1|root,COG3412@1|root,COG1080@2|Bacteria,COG1925@2|Bacteria,COG3412@2|Bacteria,1MUT8@1224|Proteobacteria,1RRCZ@1236|Gammaproteobacteria,3WVVD@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 PEP-utilising enzyme, N-terminal 1.0 dhaM 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006476,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033554,GO:0033558,GO:0034983,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0047324,GO:0050896,GO:0051716,GO:0071704,GO:0098732,GO:0140096,GO:1901564 1.0 2.7.1.121 1.0 ko:K05881 1.0 ko00561,map00561 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000,ko02000 1.0 - 1.0 - 1.0 iECs_1301.ECs1703,iSF_1195.SF1201,iS_1188.S1285,iUTI89_1310.UTI89_C1391,iZ_1308.Z1969 1.0 EIIA-man,PEP-utilisers_N,PEP-utilizers,PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03341 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism 1.0 K05881:dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84577 0 0 140108 157245 0 0 0 0 360539 193038 197675 0 0 0 0 0 0 182537 0 0 0 0 629483 782468 978760 490406 859282 1380279 932166 458928 0 885629 0 567079 513131 715900 542728 734828 1009395 0 1356201 633369 1428664 1369378 0 1212984 1314096 543692 579005 0 1357291 1402736 0 0 1022039 588058 452765 576920 487725 786831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 130183 0 0 0 0 0 0 0 0 242963 0 97226 0 0 194304 0 0 213953 119285 0 0 0 0 0 0 0 296707 0 0 0 0 0 0 0 99071 0 0 0 0 0 0 0 0 0 0 0 259542 0 257960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 97760 0 0 +(Gln->pyro-Glu)QLDEFSQSSMAK MGYG000002517_02819 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,27NBZ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection 1.0 - 1.0 - 1.0 - 1.0 ko:K09747 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 YbaB_DNA_bd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02819 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K09747:ebfC; nucleoid-associated protein EbfC 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLDESKSPSK MGYG000000251_02767;MGYG000000154_01777 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,27UW7@189330|Dorea 0.5 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_02767 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 846768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLDKFK MGYG000000074_02648 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1544@1|root,COG1544@2|Bacteria,4NUME@976|Bacteroidetes,2FTZJ@200643|Bacteroidia,22VIK@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal subunit interface protein 1.0 raiA 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02648 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K05808:hpf; ribosome hibernation promoting factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 86389 0 0 0 0 0 0 93756 0 572088 0 0 0 0 0 0 0 0 0 0 96463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 679265 0 0 0 0 0 0 93636 0 754745 0 0 0 0 0 0 0 0 0 0 657785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 695370 0 0 0 0 0 0 534785 0 753529 0 0 0 0 0 0 0 0 0 0 874283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 821825 0 0 0 0 0 0 683928 0 812204 0 0 0 0 0 0 0 0 0 0 619895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1267511 0 0 0 0 0 0 1327256 0 1834692 0 0 0 0 0 0 0 0 0 0 2206595 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLDNEIIETGKR MGYG000002293_00334;MGYG000003697_01647 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 D 1.0 Endoribonuclease that initiates mRNA decay 1.0 rny 1.0 - 1.0 - 1.0 ko:K18682 1.0 ko03018,map03018 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03019 1.0 - 1.0 - 1.0 - 1.0 DUF3552,HD,KH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00334 0.5 - - - - 1.0 1.0 1.0 1.0 RNA degradation 1.0 K18682:rny; ribonucrease Y [EC:3.1.-.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLDPLVVGQEHYDTAR MGYG000002534_04897;MGYG000002323_04215;MGYG000003390_00723;MGYG000000093_05344;MGYG000002515_03903;MGYG000002506_03402;MGYG000002494_02404;MGYG000002366_00010;MGYG000002507_04224 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,3XPEM@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 MGYG000002534_04897 0.1111111111111111 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02112:ATPF1B, atpD; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 477726 612273 337057 1155570 424820 672478 420832 488661 536968 545674 569154 485499 324119 883325 341360 578620 427362 0 0 351701 360116 520146 0 395474 382501 793101 513280 0 489169 309955 807365 317090 371755 493178 358229 887170 693675 780301 1106969 1583407 1681770 1786137 1513280 2463870 1655629 1100800 1686357 1992626 859598 1798832 1089435 1635892 1176658 1500304 2229322 0 0 1399486 1678749 2744325 0 3151173 1796181 1333054 1644631 0 1973139 2279456 1321034 1514872 1723393 1466296 1042701 1492931 1771723 1347168 457568 595729 642245 790575 369408 1101815 415274 570634 714379 458878 397723 385460 443710 480144 557670 437571 478501 0 0 612607 470282 813244 0 850490 492177 668368 601685 0 617426 529666 434240 383072 527695 718549 683446 524995 601763 718859 1152334 913697 736930 854247 870622 1192351 1611466 1362479 782344 1072408 459978 722195 693315 884688 823521 714023 943170 0 0 864244 1074348 1255916 0 1046666 1284306 1272711 1098474 0 931692 1055499 478802 811283 872106 1353794 1398723 1327507 689567 910313 0 0 0 512688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 619645 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLDYAEAGDNAGVLLR MGYG000002925_00238 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__RF39|f__UBA660|g__CAG-877|s__CAG-877 sp900548695|m__MGYG000002925 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,3VNVP@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002925_00238 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444387 0 0 0 0 324572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLEAATQSEGK MGYG000002494_04638 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,3XN3I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 1.0 - 1.0 ko:K03695 1.0 ko04213,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 MGYG000002494_04638 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - multiple species 1.0 K03695:clpB; ATP-dependent Clp protease ATP-binding subunit ClpB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 357065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLEAEETTK MGYG000003366_00226;MGYG000002963_04226;MGYG000000133_00303;MGYG000000201_03111;MGYG000001310_00228;MGYG000002670_02305;MGYG000001777_01222;MGYG000000171_02644;MGYG000003063_01532;MGYG000000268_00625;MGYG000000249_01189;MGYG000001615_01162;MGYG000000806_01491;MGYG000002492_02076;MGYG000000136_00457;MGYG000000067_00824;MGYG000000095_04662;MGYG000002602_00510;MGYG000004210_00553;MGYG000002298_01718;MGYG000000181_01147;MGYG000000489_01319;MGYG000001374_02751;MGYG000004764_00051;MGYG000000212_00037;MGYG000000252_03028;MGYG000004697_00536 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3Y05R@572511|Blautia 0.25925925925925924 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003366_00226 0.037037037037037035 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04078:groES, HSPE1; chaperonin GroES 1.0 none 1.0 0 0 264320 367207 0 553925 0 0 0 0 386550 0 170061 351892 0 0 0 208857 0 0 0 815974 520445 585760 224972 0 378428 639738 0 0 0 0 312406 0 0 118895 0 369034 0 0 399545 314420 0 173179 0 0 0 0 123357 0 279398 0 0 0 0 649036 0 0 0 0 1078224 0 0 0 174852 1130404 0 0 0 0 130265 0 0 0 0 0 0 0 720861 0 0 467199 317247 0 0 0 348737 0 0 312713 0 0 0 918716 0 0 0 395974 906273 158659 229500 0 349491 973634 0 0 0 0 460601 0 0 252358 0 510537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1307859 2609479 0 1501935 1743225 0 0 0 1801871 0 1749347 1871539 0 0 0 544684 0 0 0 1701614 583453 1295578 1517380 0 1779886 670311 0 0 0 0 2435272 0 0 1505280 0 1134364 +(Gln->pyro-Glu)QLEAEGKPAQIIEK MGYG000002485_02451;MGYG000004828_01990 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0264@1|root,COG0264@2|Bacteria,378TR@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_02451 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 504849 0 0 0 1075786 0 0 0 0 0 0 0 0 0 0 0 655828 0 453067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLEAETTTK MGYG000002528_02458;MGYG000000080_01155 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02458 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04078:groES, HSPE1; chaperonin GroES 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1976330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLEAYLGVK MGYG000000177_00608 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,36FZP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 2-hydroxyglutaryl-CoA dehydratase, D-component 1.0 - 1.0 - 1.0 1.3.7.8,4.2.1.54 1.0 ko:K04112,ko:K20627 1.0 ko00362,ko00640,ko00643,ko01100,ko01120,ko01220,map00362,map00640,map00643,map01100,map01120,map01220 1.0 M00541 1.0 R02451,R02963 1.0 RC00002,RC00818,RC01839 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HGD-D 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000177_00608 1.0 benzoyl-CoA reductase. | lactoyl-CoA dehydratase. - Inactive toward aromatic acids that are not CoA esters but will also catalyze the reaction: NH3 + acceptor + 2 ADP + 2 phosphate = hydroxylamine + reduced acceptor + 2 ATP + H2O.-!-In the presence of reduced acceptor, but in the absence of oxidizable substrate, the enzyme catalyzes the hydrolysis of ATP to ADP plus phosphate.-!-Formerly EC 1.3.99.15. | A bacterial enzyme that is involved in propanoate fermentation (also known as the acrylate pathway). 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized 2[4Fe-4S]- [ferredoxin] + 2 phosphate = 2 ATP + benzoyl-CoA + 2 H2O + reduced 2[4Fe- 4S]-[ferredoxin]. | (R)-lactoyl-CoA = acryloyl-CoA + H2O. 1.0 1.0 1.0 1.0 Benzoate degradation|Propanoate metabolism|Styrene degradation|Metabolic pathways|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04112:bcrC, badD; benzoyl-CoA reductase subunit C [EC:1.3.7.8]|K20627:lcdB; lactoyl-CoA dehydratase subunit beta [EC:4.2.1.54] 1.0 none 1.0 0 256296 0 0 0 171958 0 0 0 0 0 0 0 0 0 0 0 0 284724 0 441342 362320 0 131295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144563 0 0 0 109125 0 0 0 0 0 0 0 0 0 0 0 0 224404 0 96871 60219 0 80045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81460 0 0 182172 0 61045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLEDAVGKEEAK MGYG000001489_02765;MGYG000002218_01253;MGYG000002438_00429 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,22VVH@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001489_02765 0.3333333333333333 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382718 0 314786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527791 0 0 0 0 0 0 0 0 620641 0 0 0 0 0 0 0 0 137019 0 387430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559939 0 0 0 0 0 0 0 0 788785 0 0 0 0 0 0 0 0 661963 0 878527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470629 0 0 0 0 0 0 0 0 854457 0 0 0 0 0 0 0 0 623582 0 215042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1244083 0 0 0 0 0 0 0 0 1467185 0 0 0 0 0 0 0 0 1709091 0 967274 0 0 0 0 0 0 +(Gln->pyro-Glu)QLEDGLTEKK MGYG000000105_02189;MGYG000001346_03530;MGYG000003681_00297;MGYG000001313_01991 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 2C0G9@1|root,310GM@2|Bacteria,4NHU0@976|Bacteroidetes,2FN0C@200643|Bacteroidia,4AKKG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG19144 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000105_02189 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 699987 0 0 0 0 597257 0 0 0 0 407169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 954173 0 0 0 0 200030 0 0 0 0 759868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 940839 0 0 0 0 1071662 0 0 0 0 1273582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1058004 0 0 0 0 451135 0 0 0 0 1355583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409798 0 0 0 0 329170 0 0 0 0 355319 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLEDVC(Carbamidomethyl)GKPFDYDKFVK MGYG000000420_01196 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900553995|m__MGYG000000420 1.0 COG1775@1|root,COG1775@2|Bacteria,37BRW@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 E 1.0 2-hydroxyglutaryl-CoA dehydratase, D-component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HGD-D 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000420_01196 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 204309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244250 0 326958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 890272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521643 0 774735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLEEAGAEVELK MGYG000000053_00901;MGYG000000044_01728;MGYG000000183_03084;MGYG000003202_00136;MGYG000004468_00169;MGYG000001562_01082;MGYG000002082_01855;MGYG000003701_03116;MGYG000003279_00958;MGYG000000825_01460;MGYG000004006_00426;MGYG000003282_01991;MGYG000004830_01657;MGYG000001546_01548;MGYG000004469_00969;MGYG000002867_00700;MGYG000001655_02927;MGYG000001608_02199;MGYG000002007_00362;MGYG000001489_05034;MGYG000000003_02516;MGYG000000138_00672;MGYG000002438_02328;MGYG000000117_01470;MGYG000002033_01014;MGYG000004573_00011;MGYG000003172_00544;MGYG000002203_00881;MGYG000000254_02576;MGYG000000074_01766;MGYG000000144_02611;MGYG000003498_00517;MGYG000004711_00303;MGYG000000222_01120;MGYG000001552_00977;MGYG000004658_01198;MGYG000002556_01325 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 0.43243243243243246 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 0.972972972972973 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000053_00901 0.02702702702702703 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 237460 425548 0 0 737535 0 0 858219 569803 326847 738785 447873 0 383955 527121 0 0 0 0 581150 407889 0 412785 0 0 0 0 0 0 477833 626670 411418 291319 564689 0 0 415671 0 0 426622 0 834284 564514 0 0 0 421466 471940 755547 122108 0 280360 499519 0 0 0 0 920028 327357 0 128369 0 0 0 0 380543 556501 134649 320896 261625 0 271729 0 0 0 0 0 0 0 334256 369907 0 0 401271 564752 358244 865331 489757 0 922881 0 0 0 0 0 382382 0 0 819738 0 0 0 0 0 541752 430029 365243 391620 0 491272 0 0 765080 0 458493 664546 0 382981 628170 0 0 1126263 5921510 387778 3698569 0 0 1013992 551055 0 0 0 0 2368998 503118 0 489701 0 0 0 0 638087 5353179 734185 534412 593213 887088 6692063 0 0 897798 0 920878 470296 0 1834147 602512 0 0 781720 707171 1009177 1223284 1111398 0 541665 985360 0 0 0 0 1365208 941529 0 609366 0 0 0 0 942769 1626032 562100 1496289 238199 780002 1273483 0 0 490066 +(Gln->pyro-Glu)QLEIEREAIKR MGYG000003282_00225;MGYG000004757_00271;MGYG000001372_02360;MGYG000004885_00467;MGYG000002478_04149;MGYG000004464_01783;MGYG000000243_01129;MGYG000004797_00905;MGYG000004763_00452;MGYG000000196_01208 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,2FM5N@200643|Bacteroidia,4AKZF@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 - 1.0 - 1.0 ko:K03695 1.0 ko04213,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 MGYG000003282_00225 0.1 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - multiple species 1.0 K03695:clpB; ATP-dependent Clp protease ATP-binding subunit ClpB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLEKNPWDEYETIYTPGSVHK MGYG000003697_01824;MGYG000002080_02027 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01824 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 634229 416498 315547 0 305735 124621 0 435071 0 0 541491 365722 0 0 325404 223011 0 267308 0 0 0 340357 336424 448939 0 497403 0 310592 0 0 410595 362388 248234 0 0 0 470858 414822 387106 306770 262559 0 409189 392738 0 325499 0 0 425694 405475 273070 0 462134 442248 0 499512 0 0 0 364793 0 124541 0 538908 0 216061 0 0 285993 293753 324740 0 0 0 240823 331969 204856 0 0 0 125693 458488 0 162160 0 0 371977 374056 238940 0 0 209366 0 329747 0 0 0 190415 201074 296721 0 261783 0 164816 0 0 507523 0 271166 0 0 0 0 320505 543529 760475 2143808 0 1450622 2062416 0 782906 0 0 2191551 722113 1455361 0 1003068 1334316 0 919706 0 0 0 2064317 1526906 1504156 0 565651 0 1416852 0 0 1107755 938149 1348370 0 0 0 553649 1432758 0 0 0 0 322929 342180 0 0 0 0 330709 245330 222750 0 0 236663 0 160545 0 0 0 397742 455004 519116 0 360563 0 581188 0 0 0 257641 231859 0 0 0 0 245038 +(Gln->pyro-Glu)QLEQEQMK MGYG000002323_03125;MGYG000002477_01825;MGYG000002513_01534;MGYG000002494_04624;MGYG000001465_01866;MGYG000003360_03259;MGYG000000337_01318;MGYG000002535_00930;MGYG000002504_03064;MGYG000003883_03143;MGYG000002506_02124;MGYG000002515_00446;MGYG000002525_00836;MGYG000003372_01568;MGYG000000093_05408 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0335@1|root,COG0335@2|Bacteria,1RH3A@1224|Proteobacteria,1S5XX@1236|Gammaproteobacteria,1Y8KB@135625|Pasteurellales 0.7333333333333333 135625|Pasteurellales 0.7333333333333333 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 0.7333333333333333 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_03125 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02884:RP-L19, MRPL19, rplS; large subunit ribosomal protein L19 1.0 none 1.0 0 0 0 0 0 572785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 707710 0 496575 0 0 0 0 0 0 0 0 404207 0 0 0 0 0 0 0 765396 0 0 1206804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1295459 0 931687 0 0 0 0 0 0 0 0 684010 0 0 0 0 485902 0 0 509222 0 0 637833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211002 0 608305 0 0 0 0 0 0 0 0 234440 0 0 0 0 169434 0 0 516198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401010 0 896411 0 0 0 0 0 0 0 0 824579 0 0 0 0 380334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLESDIYNAIHR MGYG000002281_02975;MGYG000000196_02928 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 2FJH4@1|root,312SQ@2|Bacteria,4PHR0@976|Bacteroidetes,2FTF5@200643|Bacteroidia,4ARNA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 YtxH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_02975 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 616143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLFGESEGKDNK MGYG000002040_00814;MGYG000003291_01409;MGYG000002224_00441;MGYG000001319_00092;MGYG000001300_02540;MGYG000000039_01586;MGYG000001255_00391;MGYG000003899_00328;MGYG000003166_01024;MGYG000000022_00661;MGYG000000195_00211;MGYG000004679_00057;MGYG000000089_01040 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WHJX@541000|Ruminococcaceae 0.9230769230769231 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 0.9230769230769231 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002040_00814 0.07692307692307693 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 800632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507849 0 0 0 0 843048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1788125 0 0 0 0 1039423 0 0 0 0 1766897 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLFKDEVR MGYG000004552_02371;MGYG000000650_02217;MGYG000001780_04179;MGYG000001615_05534;MGYG000000029_03508;MGYG000000121_02100;MGYG000002478_04002;MGYG000004735_00074;MGYG000000174_03354;MGYG000000138_02270;MGYG000000098_03146;MGYG000001374_02303;MGYG000001346_03291;MGYG000002218_01878;MGYG000000013_02510;MGYG000002685_01245;MGYG000004769_01556;MGYG000002438_02747;MGYG000004899_02570;MGYG000003351_04375;MGYG000001493_04160;MGYG000000198_03851;MGYG000000044_00075;MGYG000002455_02568;MGYG000001617_00853;MGYG000000133_02443;MGYG000000179_04192;MGYG000001345_00044;MGYG000000222_01345 domain d__Bacteria 1.0 COG0519@1|root,COG0519@2|Bacteria,4NZSX@976|Bacteroidetes,2FNJE@200643|Bacteroidia,4AMZI@815|Bacteroidaceae 0.5517241379310345 976|Bacteroidetes 0.5517241379310345 F 1.0 Psort location Cytoplasmic, score 0.5517241379310345 - 1.0 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 0.5517241379310345 6.3.5.2 1.0 ko:K01951 1.0 ko00230,ko00983,ko01100,map00230,map00983,map01100 1.0 M00050 1.0 R01230,R01231,R08244 1.0 RC00010,RC00204 1.0 ko00000,ko00001,ko00002,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 GATase,GMP_synt_C,NAD_synthase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004552_02371 0.034482758620689655 GMP synthase (glutamine-hydrolyzing). GMP synthetase (glutamine-hydrolyzing). Involved in the de novo biosynthesis of guanosine nucleotides.-!-An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain.-!-The enzyme can catalyze the second reaction alone in the presence of ammonia.-!-Formerly EC 6.3.4.1. ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways 1.0 K01951:guaA, GMPS; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] 1.0 none 1.0 662381 676092 814647 0 838677 823317 0 0 0 0 801212 0 919731 809433 0 0 933298 539804 0 0 771556 589176 589882 695691 0 738381 0 501749 0 0 0 0 579680 0 0 0 553494 618632 0 498216 663314 0 808766 544052 0 0 0 0 1047860 0 1686057 662865 0 0 617576 234787 0 0 745888 574960 392707 377283 0 591895 0 295171 0 0 0 0 710678 0 0 0 656123 1295850 520380 683909 1058457 0 820048 1124406 0 0 0 0 0 0 739562 1340278 0 0 1316098 700424 0 0 827891 738251 1200572 1258707 0 584672 0 744184 0 0 0 0 445914 0 0 0 837033 835751 455674 1293306 1165651 0 352939 1214026 0 0 0 0 1139765 0 1648590 1149616 0 0 1378665 3332145 0 0 1969941 700510 1356525 1456133 0 782820 0 965100 0 0 0 0 1765766 0 0 0 648496 1156982 1407314 1333922 679152 0 2468113 2439210 0 0 0 0 1580146 0 2000881 837193 0 0 2317527 12565386 0 0 1175387 2240695 1081187 2916598 0 899114 0 0 0 0 0 0 1407548 0 0 0 1761216 1445527 +(Gln->pyro-Glu)QLGAIHR MGYG000002478_02225;MGYG000000243_00756;MGYG000004797_02333 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1605@1|root,COG2876@1|root,COG1605@2|Bacteria,COG2876@2|Bacteria,4NDU4@976|Bacteroidetes,2FPF1@200643|Bacteroidia,4AMCM@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 pheB 1.0 - 1.0 5.4.99.5 1.0 ko:K04516 1.0 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 1.0 M00024,M00025 1.0 R01715 1.0 RC03116 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CM_2,DAHP_synth_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02225 0.3333333333333333 chorismate mutase. hydroxyphenylpyruvate synthase. - chorismate = prephenate. 1.0 1.0 1.0 1.0 Phenylalanine, tyrosine and tryptophan biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K04516:AROA1, aroA; chorismate mutase [EC:5.4.99.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLGALVYSLHK MGYG000003937_00998;MGYG000004866_01442;MGYG000000724_00536;MGYG000000084_02378;MGYG000001157_00384;MGYG000003921_00769;MGYG000002059_00009 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 2ET0Z@1|root,33KJ7@2|Bacteria,1VNW5@1239|Firmicutes,254DV@186801|Clostridia,3WQEJ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-ribbon_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_00998 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 211763 0 0 0 0 0 228811 0 0 0 0 256676 0 0 0 0 0 0 342258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 765455 0 0 0 0 0 227847 0 0 0 0 352938 0 0 0 0 272862 0 665937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265150 0 0 0 0 0 109833 0 0 0 0 0 0 0 0 0 137806 0 173307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476543 0 0 0 0 0 752932 0 0 0 0 687389 0 0 0 0 2352346 0 549365 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLGEDPWVAIAKR MGYG000002534_01740;MGYG000000093_01905;MGYG000002515_01006;MGYG000002535_02781;MGYG000002477_03740;MGYG000002506_00237;MGYG000002494_01406;MGYG000002323_01525 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,1RMFY@1236|Gammaproteobacteria,3Z8AH@586|Providencia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002534_01740 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2401767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLGFDAIHDTVHEM(Oxidation)AKDEAR MGYG000004828_01486;MGYG000004893_01870;MGYG000002485_00254 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG1592@1|root,COG1592@2|Bacteria,378I0@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004828_01486 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 523782 0 0 0 370038 0 0 0 0 0 0 0 0 0 0 0 513669 0 378506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLGFDAIHDTVHEMAK MGYG000004893_01870;MGYG000002485_00254 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG1592@1|root,COG1592@2|Bacteria,378I0@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004893_01870 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 499659 0 0 642902 0 0 0 513361 213987 0 0 0 0 634123 0 0 0 0 0 625063 0 471046 0 0 0 0 0 0 0 0 431198 0 0 0 0 232216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLGFDAIHDTVHEMAKDEAR MGYG000004828_01486;MGYG000004893_01870;MGYG000002485_00254 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG1592@1|root,COG1592@2|Bacteria,378I0@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004828_01486 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 145171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63420 0 0 0 0 0 0 0 598046 0 0 1614707 0 0 0 1034020 815965 332623 586955 0 0 1467472 1015086 0 0 0 0 1387139 0 809546 0 0 367793 0 0 0 736317 525215 481084 0 0 0 0 477160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLGHDVTIYEAMPK MGYG000000133_01493 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WCXB@538999|Clostridiales incertae sedis 1.0 186801|Clostridia 1.0 C 1.0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 1.0 - 1.0 - 1.0 1.17.1.9,1.3.1.1 1.0 ko:K00123,ko:K17722 1.0 ko00240,ko00410,ko00630,ko00680,ko00770,ko01100,ko01120,ko01200,map00240,map00410,map00630,map00680,map00770,map01100,map01120,map01200 1.0 M00046 1.0 R00519,R00977,R01414,R11026 1.0 RC00072,RC00123,RC02796 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_20,Fer4_6,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,NAD_binding_1,NAD_binding_8,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01493 1.0 formate dehydrogenase. | dihydrouracil dehydrogenase (NAD(+)). NAD(+)-formate dehydrogenase. The enzyme from most aerobic organisms is devoid of redox-active centers but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centers, flavin and a molybdenum center.-!-Together with EC 1.12.1.2, forms a system previously known as formate hydrogenlyase.-!-Formerly EC 1.2.1.2. | The enzyme was originally discovered in the uracil-fermenting bacterium, Clostridium uracilicum, which utilizes uracil and thymine as nitrogen and carbon sources for growth.-!-Since then the enzyme was found in additional organisms including Alcaligenes eutrophus, Pseudomonas strains and Escherichia coli. formate + NAD(+) = CO2 + NADH. | (1) 5,6-dihydrouracil + NAD(+) = H(+) + NADH + uracil. (2) 5,6-dihydrothymine + NAD(+) = H(+) + NADH + thymine. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|beta-Alanine metabolism|Glyoxylate and dicarboxylate metabolism|Methane metabolism|Pantothenate and CoA biosynthesis|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00123:fdoG, fdhF, fdwA; formate dehydrogenase major subunit [EC:1.17.1.9]|K17722:preT; dihydropyrimidine dehydrogenase (NAD+) subunit PreT [EC:1.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 813401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLGIDPAELGYSSKK MGYG000001636_00136;MGYG000003266_00909;MGYG000002050_01081;MGYG000001718_00229;MGYG000002970_01274;MGYG000002775_00112 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CUFQ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 - 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001636_00136 0.16666666666666666 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLGITTGAQAK MGYG000000356_01643;MGYG000000389_01367;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000356_01643 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 5047509 2681990 2681943 8435829 3161624 3866282 4753950 4888230 5043829 6209966 3473304 6853979 3840799 5180466 6304334 3491081 6233179 0 6557443 4864801 6054437 3986651 0 5317481 4710913 5646486 6751651 0 581428 6398966 2579172 2072341 2870593 6541602 4903345 5290305 5776432 1953244 0 0 0 103232 342140 384240 0 209866 323486 328365 352532 0 240249 588046 0 408058 384612 0 272767 173132 292171 0 0 187688 198616 0 252198 0 0 514646 91879 0 0 448055 0 190343 0 193658 2521118 635498 626321 1979093 1543634 1056503 2197304 2729254 3378344 1937448 2677645 3825117 2080562 3006039 2624362 1681129 1737691 0 1917013 2120370 1426861 0 0 0 3233678 3301924 2679175 0 669305 2751623 562624 0 709668 1564316 2832979 3053681 3437405 730980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17753541 10240148 17779326 6572921 25123271 24906230 10839542 11847431 20676229 23520384 16524060 17014857 19355567 12395590 24847469 12773123 19362498 0 18366869 16036698 11173507 13754269 0 23246244 21385125 18755177 14737758 0 4440428 19789156 14392721 6795971 11422907 17561743 16835225 15864405 29373351 19370065 +(Gln->pyro-Glu)QLGITTGQQAK MGYG000004271_01770;MGYG000000271_01499 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01770 0.5 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3759680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 393695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLGKDVIVDGVNKR MGYG000002528_01293;MGYG000000028_01644 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,25VI8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 2.2.1.2,5.3.1.9 1.0 ko:K01810,ko:K13810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00004,M00007,M00114 1.0 R01827,R02739,R02740,R03321 1.0 RC00376,RC00439,RC00563,RC00604 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01293 0.5 transaldolase. | glucose-6-phosphate isomerase. glycerone transferase. | phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]|K13810:tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187074 0 0 95479 0 0 0 0 0 0 0 438152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312039 0 0 0 0 0 0 0 87506 0 0 0 0 0 0 0 1328237 0 0 0 473748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025835 0 398638 0 0 0 0 881341 0 0 1121166 0 0 0 0 0 0 0 265917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 627490 0 0 228181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLGNDVVVDGVNKR MGYG000000262_02071 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,25VI8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 2.2.1.2,5.3.1.9 1.0 ko:K01810,ko:K13810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00004,M00007,M00114 1.0 R01827,R02739,R02740,R03321 1.0 RC00376,RC00439,RC00563,RC00604 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02071 1.0 transaldolase. | glucose-6-phosphate isomerase. glycerone transferase. | phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]|K13810:tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 793717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLGPVTKPM(Oxidation)PEWK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 0.5 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 453601 196132 0 0 375003 0 0 0 244831 0 0 365343 0 439220 676789 296940 0 257408 0 0 738435 0 0 0 0 0 0 0 0 0 312700 0 0 311174 0 0 0 156156 419088 0 247064 0 0 430775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 583678 0 0 165493 0 0 294853 0 1399015 2842631 234611 1951061 0 1705232 393551 1278693 0 1294426 370544 0 1177735 1037284 1572337 1146491 1114499 0 1837636 1695580 958619 1798193 0 981103 1496393 1447432 1949898 0 0 988478 270724 1373644 715562 1529436 1615009 0 1186931 0 662356 862842 511005 863341 0 995411 1059252 640160 0 1649559 486678 0 1091173 895828 436660 1272747 982624 0 476336 1300595 652492 1092872 0 1086181 677584 251338 567854 0 0 743515 637145 542020 774963 422145 659702 0 361206 424668 353695 718318 837994 568036 0 619450 446179 462310 0 553991 864547 0 906153 525759 558139 833950 448867 0 586881 420003 330708 662414 0 489818 491091 537899 698626 0 0 364300 949777 839205 966202 725700 334997 0 837201 882232 +(Gln->pyro-Glu)QLGPVTKPMPEWK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 0.5 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 2362496 7024492 3569426 1082066 5504521 3824383 842144 4043044 1308150 3656282 2462552 3303216 5681737 1936518 3089967 4050986 1932168 0 3218609 3003900 2013911 4517448 0 1434226 3673290 1887562 2272090 0 1727906 1874745 1713347 4705674 1781935 2106689 2480635 1170309 1404655 2104692 7009771 6163027 1770746 4423310 2156261 4087961 13691438 5251512 4566121 3456940 2124434 3148768 3188120 3281546 3871717 1800105 3201053 0 5828207 7551381 4334158 3148833 0 8166936 4888513 6137554 6642473 0 8318249 3816863 5024516 3662834 1666144 6100987 5047032 7365319 4812321 1742662 15230091 16250424 3602510 18505325 2256665 15295529 3634104 14233988 4566371 13063682 4800545 9675142 11890818 9870113 20016472 12208949 12975970 0 20438570 17411305 12411782 22209770 0 7982668 18800337 15977021 20435822 0 2795450 10509395 3823473 12821648 8612544 21856814 19366070 4761068 12826127 3259875 6504139 10023457 4401597 9656709 6610808 12641788 12801391 7673380 5978184 17356296 6060544 3364182 11813460 7426321 6637142 14975212 11729787 0 4350046 11144903 5650761 10465932 0 10635658 6697249 3427781 8000157 0 9684887 8021260 4739242 5772087 6889856 4056835 7001610 4417096 3341659 6136353 5338033 9195949 10675143 6374842 13804040 6182627 3739249 5338166 5738525 7673668 9047061 6096987 12185979 4367931 8178946 10862360 7560375 0 7848216 6443334 5726118 8103441 0 4960320 5731420 5976516 6987306 0 2434443 8004038 12877813 11249016 14144741 9245559 7488861 5346975 8155813 10867325 +(Gln->pyro-Glu)QLGSDFPSDPVEQLK MGYG000000089_02490 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000089_02490 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLHFGVR MGYG000003683_00463;MGYG000002469_01094;MGYG000001292_01123 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Belongs to the transketolase family 1.0 tkt 1.0 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA,Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00463 0.3333333333333333 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 161840 0 370902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 266913 0 0 0 0 0 0 0 78545 0 131518 0 0 0 0 176800 0 0 0 79184 263585 637458 705326 890615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3046327 0 0 0 0 1197242 0 0 523069 0 2441593 0 0 1565617 0 652184 0 0 0 588893 1042587 456372 534652 572263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230585 0 0 0 0 0 0 0 530320 0 393857 0 0 0 0 910571 0 0 0 398898 410754 191568 349458 280246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242996 0 0 0 0 0 0 0 91359 0 586489 0 0 801238 0 356659 0 0 0 144569 279339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 51362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53911 0 +(Gln->pyro-Glu)QLHTAETEK MGYG000003697_01373;MGYG000002050_01273 domain d__Bacteria 1.0 COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,2FMVJ@200643|Bacteroidia 0.5 976|Bacteroidetes 0.5 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 - 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DUF1398,Metalloenzyme,PglZ,Phosphodiest,iPGM_N 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01373 0.5 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K15633:gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7516624 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLHVGQEEADPVTGAR MGYG000002517_01802 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 O-acetylhomoserine 1.0 metY 1.0 - 1.0 2.5.1.49 1.0 ko:K01740 1.0 ko00270,ko01100,map00270,map01100 1.0 - 1.0 R01287,R04859 1.0 RC00020,RC02821,RC02848 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01802 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways 1.0 K01740:metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] 1.0 none 1.0 493262 0 0 302146 0 0 0 0 0 0 0 0 0 0 284582 0 0 0 0 402268 0 0 0 0 336404 218369 335109 0 0 494933 0 0 0 0 406153 479073 426943 0 464469 0 0 249673 0 0 0 0 0 0 0 0 0 0 438635 0 0 0 0 356588 0 0 0 0 455955 678139 468946 0 0 489042 0 0 0 0 566833 481613 364778 0 276237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337347 0 0 1510958 0 0 2452608 0 0 0 0 0 0 0 0 0 0 1652410 0 0 0 0 706837 0 0 0 0 1468542 1061134 1952342 0 0 1424280 0 0 0 0 1025861 1670921 890553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLIAGAEPMVR MGYG000000133_01657 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes,257WP@186801|Clostridia,3Y0N6@572511|Blautia 1.0 186801|Clostridia 1.0 K 1.0 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits 1.0 rpoZ 1.0 - 1.0 2.7.7.6 1.0 ko:K03060 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01657 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03060:rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 503312 0 0 0 0 0 +(Gln->pyro-Glu)QLIAQSWHTDEIRK MGYG000002494_01897;MGYG000002515_03682 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2352@1|root,COG2352@2|Bacteria,1MUD5@1224|Proteobacteria,1RPTP@1236|Gammaproteobacteria,3X00P@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle 1.0 ppc 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.0 4.1.1.31 1.0 ko:K01595 1.0 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 1.0 M00168,M00170,M00171,M00172,M00173,M00346,M00374 1.0 R00345 1.0 RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iSFV_1184.SFV_4025 1.0 PEPcase,PEPcase_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01897 0.5 phosphoenolpyruvate carboxylase. phosphoenolpyruvic carboxylase. This enzyme replenishes oxaloacetate in the tricarboxylic acid cycle when operating in the reverse direction.-!-The reaction proceeds in two steps: formation of carboxyphosphate and the enolate form of pyruvate, followed by carboxylation of the enolate and release of phosphate. oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01595:ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31] 1.0 none 1.0 0 162936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179315 0 181031 0 0 0 0 0 0 0 0 185319 0 0 0 0 161963 0 358115 773784 0 0 1728067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1463925 0 1039268 0 0 0 0 0 0 0 0 306302 0 0 0 0 302000 0 289441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107167 0 344240 0 0 0 0 0 0 0 0 0 0 0 0 0 257343 0 344955 258002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181350 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92487 0 0 0 0 0 +(Gln->pyro-Glu)QLIAYDALNR MGYG000004757_00444 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__UBA6398|s__UBA6398 sp900555645|m__MGYG000004757 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004757_00444 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1589164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLIDAVIGR MGYG000001787_02109;MGYG000001306_03249;MGYG000001599_00729;MGYG000000273_01081;MGYG000002478_04323;MGYG000003420_00356;MGYG000000042_02614;MGYG000000243_00993;MGYG000001925_01151;MGYG000001364_01802;MGYG000000781_01397;MGYG000003693_02828 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4656@1|root,COG4656@2|Bacteria,4NIS7@976|Bacteroidetes,2FMAQ@200643|Bacteroidia,4AM9Y@815|Bacteroidaceae 0.9166666666666666 976|Bacteroidetes 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4_10,Fer4_17,Fer4_7,Fer4_8,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001787_02109 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03615:rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56169 0 0 0 0 123641 0 0 0 0 68667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180256 0 0 0 0 290925 0 0 0 0 276020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67066 0 0 0 0 133787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLIEC(Carbamidomethyl)LQPNRR MGYG000003022_01750;MGYG000003352_01361 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,1KIWG@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 M 1.0 Belongs to the ompA family 1.0 ompA 1.0 - 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 - 1.0 DUF1134,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003022_01750 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03286:TC.OOP; OmpA-OmpF porin, OOP family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1920377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2320097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLIYTAR MGYG000000127_04024;MGYG000000262_02232;MGYG000000077_02465;MGYG000001707_00050 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,36EDS@31979|Clostridiaceae 0.5 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 1.0 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000127_04024 0.25 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLKAEEILPR MGYG000001415_00421;MGYG000003279_00276;MGYG000004756_00243;MGYG000001302.1_01584;MGYG000004536_01290;MGYG000000003_01073 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,4PKTH@976|Bacteroidetes,2G35Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Conserved carboxylase domain 1.0 - 1.0 - 1.0 4.1.1.3,6.4.1.1 1.0 ko:K01571,ko:K01960 1.0 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 1.0 M00173,M00620 1.0 R00217,R00344 1.0 RC00040,RC00367 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 Biotin_lipoyl,Biotin_lipoyl_2,HMGL-like,OAD_gamma,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_00421 0.16666666666666666 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | pyruvate carboxylase. | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). pyruvic carboxylase. | oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The animal enzyme requires acetyl-CoA. | The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. ATP + hydrogencarbonate + pyruvate = ADP + H(+) + oxaloacetate + phosphate. | H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]|K01960:pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] 1.0 none 1.0 0 0 0 0 0 541424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324658 0 421572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLKAEVPEFR MGYG000000133_01766;MGYG000000271_00796 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,3Y019@572511|Blautia 0.5 186801|Clostridia 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 - 1.0 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01766 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02884:RP-L19, MRPL19, rplS; large subunit ribosomal protein L19 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLKQDPWETIEEKYPVGSK MGYG000004797_04001;MGYG000000196_00547;MGYG000001378_02385;MGYG000002281_02540;MGYG000002455_03377;MGYG000000243_01228;MGYG000002478_02960 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_04001 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 3051290 2534350 5125146 2296873 3925746 2342427 2882963 2725733 3080810 3809195 3365922 2802251 5110706 3739307 2776799 4383169 2539583 1396910 3025222 2614305 2630153 2012267 1544129 3096876 3132567 3402361 3510370 805308 2718121 3712457 3842764 4029305 4769257 2992911 2885782 3011211 2820688 4791038 2114350 1150788 1842222 2262434 2840515 2126429 2111374 2447261 1842330 2955437 3466976 2347965 4656552 2361412 2388678 3895527 2328214 569320 2684657 1686753 2183744 2186696 899357 1658097 2457423 2537562 2058538 955953 2753509 3001515 1301182 2180658 1644516 2135273 2556045 1956020 2229379 1547265 1636612 788787 1725806 1451113 2612475 1635541 1477552 1521573 1585462 1446876 1721935 1733544 3233385 1541384 1384834 2291203 1250464 2000413 1392182 1330743 1263083 1176708 1596909 1480142 1303675 1604799 1227889 1423410 1297955 1301757 1578872 989653 1478320 1659967 1486050 1829014 1343692 1620745 836736 856411 1203116 912772 1062272 1071834 918896 1090127 1031988 1140952 1573486 1260566 1827066 959306 885011 1402911 1020182 818190 1089206 924245 1352126 1065222 1295683 973123 1254012 1152404 1229757 899323 969965 1064966 837266 1567582 1092734 1113322 1294211 1320891 1358840 1211750 1546605 1497460 1174268 286711 2843124 1766323 1874957 1677545 1763837 1168181 1763733 1597997 5687378 1147811 1733761 3214082 1922595 1863304 1738880 1880559 1618892 2104288 1743003 1763904 1847139 2308625 1797545 2195463 1721213 2380000 1509566 1708433 1043859 2785807 2497058 1385188 2053454 1610290 +(Gln->pyro-Glu)QLKTPEEVAR MGYG000000184_01189;MGYG000004296_00406;MGYG000001338_02790 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_01189 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 913535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1144499 0 0 0 0 0 0 0 810118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382292 0 0 0 0 0 0 0 1672450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1107214 0 0 0 0 0 0 0 1543291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 855298 0 0 0 0 0 0 0 1025647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248957 0 0 0 0 0 0 +(Gln->pyro-Glu)QLLASGVGQTSR MGYG000002478_01914;MGYG000002281_00881;MGYG000004876_02356;MGYG000003312_02923;MGYG000000196_00013;MGYG000001787_00420;MGYG000003202_01366;MGYG000002561_01112;MGYG000000013_00011;MGYG000004019_02126;MGYG000001346_03669;MGYG000000224_02757;MGYG000003221_01732;MGYG000002455_04536;MGYG000003252_06179;MGYG000002120_00051;MGYG000000243_02236;MGYG000002171_02209;MGYG000004763_02744;MGYG000001370_01226 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0138@1|root,COG0138@2|Bacteria,4NEZD@976|Bacteroidetes,2FN3G@200643|Bacteroidia,4AK6B@815|Bacteroidaceae 0.85 976|Bacteroidetes 1.0 F 1.0 bifunctional purine biosynthesis protein PurH 0.85 purH 1.0 - 1.0 2.1.2.3,3.5.4.10 1.0 ko:K00602 1.0 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 1.0 M00048 1.0 R01127,R04560 1.0 RC00026,RC00263,RC00456 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 AICARFT_IMPCHas,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01914 0.05 phosphoribosylaminoimidazolecarboxamide formyltransferase. | IMP cyclohydrolase. aminoimidazolecarboxamide ribonucleotide transformylase. | inosinicase. - (6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. | H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. 1.0 1.0 1.0 1.0 Purine metabolism|One carbon pool by folate|Metabolic pathways|Biosynthesis of secondary metabolites|Antifolate resistance 1.0 K00602:purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 130469 0 262469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 806907 0 568903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294605 0 344082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575220 0 215942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450123 0 438726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLLEAEGKYDIK MGYG000003697_01280;MGYG000002293_01727 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,2FSGZ@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 1.0 rpsI 1.0 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01280 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02996:RP-S9, MRPS9, rpsI; small subunit ribosomal protein S9 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1643413 0 0 0 0 2302397 0 0 0 0 1724675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150942 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLLEAGVHFGHQTR MGYG000000022_01263;MGYG000000150_02990;MGYG000000067_03067;MGYG000004221_00411;MGYG000004252_01040;MGYG000002610_00266;MGYG000001675_01243;MGYG000000280_00470;MGYG000000080_02857;MGYG000002098_01442;MGYG000001185_00083;MGYG000003695_01035;MGYG000002788_00212;MGYG000001444_00261;MGYG000002517_01401;MGYG000000404_00635;MGYG000001315_00796;MGYG000002274_00630;MGYG000004788_00490;MGYG000001564_00846;MGYG000003133_02718;MGYG000000417_00486;MGYG000000141_02711;MGYG000002224_00296;MGYG000000743_01190;MGYG000004735_00874;MGYG000000278_03745;MGYG000000136_00722;MGYG000004727_01767;MGYG000000214_00298;MGYG000001319_00659;MGYG000000392_00214;MGYG000002530_00769;MGYG000004628_02226;MGYG000000089_01181;MGYG000002993_00244;MGYG000001470_02362;MGYG000002492_01612;MGYG000000163_01035;MGYG000002272_01435;MGYG000003939_00421;MGYG000000201_03495;MGYG000000073_00924;MGYG000002994_00756;MGYG000001627_01481;MGYG000000213_00523;MGYG000004769_00832;MGYG000000071_00548;MGYG000003504_00560;MGYG000002121_00509;MGYG000002212_02444;MGYG000000195_01345;MGYG000000255_00471;MGYG000000271_00181;MGYG000001477_01559;MGYG000000002_01239;MGYG000003210_01100;MGYG000001646_00858;MGYG000002042_01031;MGYG000001651_01608;MGYG000000733_01113;MGYG000002702_01822;MGYG000001027_00474;MGYG000001615_00539;MGYG000001577_01277;MGYG000001658_01304;MGYG000000370_00988;MGYG000002975_00796;MGYG000001814_01311;MGYG000000251_01121;MGYG000004517_01292;MGYG000001469_00549;MGYG000003891_01770;MGYG000002113_00203;MGYG000001645_00483;MGYG000002965_01988;MGYG000001186_00373;MGYG000000217_03427;MGYG000002829_03341;MGYG000004719_00253;MGYG000000179_02939;MGYG000001157_00347;MGYG000000185_02697;MGYG000004717_00864;MGYG000004271_02124;MGYG000004526_00583;MGYG000001356_02488;MGYG000002651_00048;MGYG000003858_00045;MGYG000000039_00227;MGYG000000142_01133;MGYG000003355_04406;MGYG000004337_01667;MGYG000004898_00338;MGYG000004833_01801;MGYG000000562_00434;MGYG000004594_00211;MGYG000002563_01003;MGYG000004726_02941;MGYG000004296_02310;MGYG000004158_00495;MGYG000004540_00402;MGYG000000515_00532;MGYG000000312_01585;MGYG000000184_03160;MGYG000001300_00246;MGYG000002223_00595;MGYG000003868_00872;MGYG000004747_01385;MGYG000001553_01735;MGYG000002279_01755;MGYG000002026_00906;MGYG000002545_00160;MGYG000004087_03021;MGYG000000389_00258;MGYG000000258_00990;MGYG000002298_01550;MGYG000000164_02268;MGYG000003921_00807;MGYG000001309_02528;MGYG000001310_00255;MGYG000002393_02328;MGYG000003937_00035;MGYG000002641_00104;MGYG000000365_00889;MGYG000002880_01067;MGYG000000909_00277;MGYG000004667_02980;MGYG000004866_00093;MGYG000002956_00421;MGYG000002528_02846;MGYG000000249_01234;MGYG000000031_01448;MGYG000003494_01022;MGYG000001247_01746;MGYG000000099_00254;MGYG000000146_01613;MGYG000004805_00611;MGYG000000187_01168;MGYG000000262_02774;MGYG000000242_00797;MGYG000002304_00361;MGYG000001786_00366 domain d__Bacteria 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 0.3076923076923077 186801|Clostridia 0.8251748251748252 J 1.0 Belongs to the universal ribosomal protein uS2 family 0.9090909090909091 rpsB 1.0 - 0.9300699300699301 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 0.993006993006993 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01263 0.006993006993006993 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 1647679 1865683 1806652 1453488 1581215 1981296 1504279 1442839 1374257 1535217 2031250 1902222 1920813 1747033 1693774 1624955 2175126 2047440 1214416 1555962 1709020 2101478 2070713 1503695 1765360 1703131 1654242 2381605 1864277 2112528 1548680 1746002 1495143 1587083 1555678 1605308 1592533 1269088 1897069 1341816 1642257 2192436 2072880 1227139 1653858 1924900 1653335 1257217 2530040 1768005 1573891 1306377 1759316 1404121 1705189 767638 1257709 1390550 1111768 1154569 609464 1676177 1336225 1536499 1616774 878452 1208884 1437473 2520023 1963947 1403385 1611996 1851955 1812358 1051410 2150907 1847638 3412060 2744571 2029745 2185919 2439026 1890566 2301984 1660936 1653085 2407466 2931111 2685459 2103638 2034248 2687630 2582752 1820342 2313332 1978736 2597763 2653443 2347017 2525049 1589927 1947195 2141425 3101617 2242362 3022866 2115707 3019194 3225451 2638789 2535619 2083189 1833277 3095289 947819 382871 489912 493182 405988 374920 550991 708125 544939 443901 354132 650675 436025 525335 592538 105218 350225 123252 450193 550450 734173 192715 437572 0 872766 879604 774213 0 85893 754986 125296 649614 354708 944509 839752 681505 628248 151479 2950668 3221314 0 0 1999569 2169806 0 0 0 0 2277428 0 1712601 3285645 3094610 0 2645425 892632 0 2242683 0 2571073 1203119 2029729 3118471 2394862 2638362 1478951 0 1926611 0 0 5540275 0 2422301 2463531 2800825 0 +(Gln->pyro-Glu)QLLEAGVHFGHQTRR MGYG000000022_01263;MGYG000001300_00246;MGYG000000201_03495;MGYG000002279_01755;MGYG000001675_01243;MGYG000000255_00471;MGYG000000271_00181;MGYG000004271_02124;MGYG000000002_01239;MGYG000000164_02268;MGYG000002517_01401;MGYG000000404_00635;MGYG000001315_00796;MGYG000002274_00630;MGYG000001310_00255;MGYG000003937_00035;MGYG000002042_01031;MGYG000002975_00796;MGYG000004898_00338;MGYG000001814_01311;MGYG000000251_01121;MGYG000002528_02846;MGYG000000562_00434;MGYG000004296_02310;MGYG000004158_00495;MGYG000004540_00402;MGYG000001319_00659;MGYG000004805_00611;MGYG000000187_01168;MGYG000000312_01585;MGYG000001470_02362 domain d__Bacteria 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 0.2903225806451613 186801|Clostridia 0.8709677419354839 J 1.0 Belongs to the universal ribosomal protein uS2 family 0.8064516129032258 rpsB 1.0 - 0.9354838709677419 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01263 0.03225806451612903 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLLENLAYVLDGR MGYG000002274_01132;MGYG000000195_01163 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 fprA2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Flavodoxin_1,Flavodoxin_5,Lactamase_B,Lactamase_B_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_01132 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178778 0 0 0 0 333111 0 0 0 0 273757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 637823 0 0 0 0 1114695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1157025 0 0 0 0 0 0 0 0 0 1759353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 947920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLLGLVC(Carbamidomethyl)AK MGYG000002080_00556;MGYG000003697_01453;MGYG000000272_00830;MGYG000002293_00490;MGYG000002834_00455 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,2FNEG@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center 1.0 rplF 1.0 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02933 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002080_00556 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02933:RP-L6, MRPL6, rplF; large subunit ribosomal protein L6 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527379 0 0 270181 0 0 0 0 376290 0 401544 0 0 0 0 285023 0 0 0 224461 368512 226253 0 0 0 248900 0 0 0 0 396404 0 146832 0 0 487478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLLGQVC(Carbamidomethyl)SK MGYG000000236_01772;MGYG000001306_02675;MGYG000000196_04004;MGYG000000243_01956;MGYG000003221_02008;MGYG000001346_01504;MGYG000002470_01215;MGYG000000224_00461;MGYG000000054_03873;MGYG000001461_00419;MGYG000003282_01795;MGYG000002478_00784;MGYG000003363_02276;MGYG000000098_01987;MGYG000000043_02831;MGYG000003693_00208;MGYG000000273_00391;MGYG000004479_01417;MGYG000002549_02910;MGYG000000781_00863;MGYG000000042_01076;MGYG000002560_00251;MGYG000001599_01836;MGYG000004185_01148;MGYG000001433_02291;MGYG000002281_02260;MGYG000002291_02240;MGYG000004763_00941 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0097@1|root,COG0097@2|Bacteria,4NGJM@976|Bacteroidetes,2FNEG@200643|Bacteroidia,4AKP6@815|Bacteroidaceae 0.9642857142857143 976|Bacteroidetes 1.0 J 1.0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center 1.0 rplF 1.0 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02933 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_01772 0.03571428571428571 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02933:RP-L6, MRPL6, rplF; large subunit ribosomal protein L6 1.0 none 1.0 398632 0 0 370719 155906 248642 0 347894 171209 226121 517156 0 0 500584 0 524224 0 0 314811 0 0 245145 0 453531 0 445631 644932 0 0 0 0 0 0 0 400255 0 404903 0 669335 0 0 841824 810562 529295 0 806340 664359 749563 1042247 0 0 1156292 0 825820 0 0 524269 0 0 411482 0 301445 0 759625 878989 0 0 0 0 0 0 0 1485796 0 723567 0 360754 0 0 367840 480541 334499 0 486797 404191 0 482473 0 0 219222 0 374249 0 0 146127 0 0 545712 0 185981 0 378870 332883 0 0 0 0 0 0 0 458590 0 379709 0 766925 0 0 301476 119948 0 0 524468 184577 258262 248126 0 0 273644 0 204044 0 0 147483 0 0 0 0 0 0 266630 422694 0 0 0 0 0 0 0 318115 0 133300 0 171526 0 0 293616 262067 521295 0 607075 622806 341762 696791 0 0 177700 0 704343 0 0 461133 0 0 644957 0 729059 0 443254 402534 0 0 0 0 0 0 0 174158 0 544523 0 +(Gln->pyro-Glu)QLLLAEKAEK MGYG000002298_00901;MGYG000002966_01704;MGYG000000133_01628;MGYG000000301_00396;MGYG000002985_01307;MGYG000000031_02579;MGYG000003012_01436;MGYG000000184_00844;MGYG000000200_00811;MGYG000000806_02010;MGYG000000212_00769;MGYG000003821_00638;MGYG000000142_00939;MGYG000004733_03028;MGYG000000213_01134;MGYG000001338_01638 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3XZ91@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 9.98 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_00901 0.0625 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1|K03527:ispH, lytB; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] 1.0 none 1.0 0 466052 400396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332312 0 0 0 0 280284 0 779258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1194069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1567692 1129825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2634398 0 0 0 0 1288943 +(Gln->pyro-Glu)QLLSDEIMGR MGYG000004735_02134 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG2221@1|root,COG2221@2|Bacteria,1UI1A@1239|Firmicutes,25EAA@186801|Clostridia,27UCZ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Nitrite/Sulfite reductase ferredoxin-like half domain 1.0 dsvA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 C_GCAxxG_C_C,Fer4,Fer4_10,NIR_SIR,NIR_SIR_ferr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_02134 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 462980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLLVAAKK MGYG000002528_00408 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00408 1.0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1|K03527:ispH, lytB; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] 1.0 none 1.0 0 0 0 0 0 239007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275392 0 293924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 751269 0 217656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLLVAERAEK MGYG000001315_00738;MGYG000002279_00513 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,27V5D@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 S1 RNA binding domain 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_00738 0.5 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1|K03527:ispH, lytB; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLLVMTNADNPR MGYG000002545_01217;MGYG000002274_02693;MGYG000000022_02788;MGYG000003899_02226;MGYG000002105_00879;MGYG000003921_00033;MGYG000003166_00833;MGYG000001300_02837;MGYG000001255_00900;MGYG000002040_00906;MGYG000000039_02141 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002545_01217 0.09090909090909091 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 524234 611400 1059332 878757 185443 737908 453941 517311 795807 846686 865957 657460 853677 627815 752789 743742 623169 1000549 994416 710775 402620 741846 1016718 519040 692377 683804 767352 1367939 147077 567616 913715 306522 1116946 807334 489113 619533 614456 816920 2128455 1705889 1783819 2571206 1904326 2059502 3068223 1223143 1815428 1045797 2060565 2091513 1367527 2689139 2284191 1181612 2068466 1455414 3095626 2950345 1389205 1088211 1351746 1759184 3386086 2558413 2873636 1584560 688934 1390038 2284206 1755548 1535102 1862337 596905 2234442 1948417 1024832 483388 475924 473109 626522 478836 364175 349566 592080 438956 245710 445213 415008 480942 481763 405235 499768 355349 977802 436982 610917 514322 342169 842569 177888 452163 554748 494180 1352933 235024 525139 543398 352002 304592 725849 525623 211339 361622 252751 626812 871596 1086655 745496 763079 989803 762481 162844 757050 664207 821207 997518 886304 742421 708285 931060 773773 406884 793122 826117 719710 1036846 666363 749075 677582 629598 694351 570750 492274 778038 1094043 902639 831604 555092 145306 660669 710934 765312 473412 0 429081 612724 0 430022 0 498332 514846 392121 190472 235789 441168 482108 395350 432831 515732 0 185154 0 432903 0 0 304841 674790 365827 541035 0 942535 318367 442892 540342 410326 852922 490857 0 484120 396095 +(Gln->pyro-Glu)QLMGPGGGLTIFHGTK MGYG000000196_05082;MGYG000002218_00631;MGYG000000196_01061;MGYG000002549_04148 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,4AP35@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 S 1.0 Tat pathway signal sequence domain protein 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal 1.0 - 1.0 GH109 0.75 - 1.0 - 1.0 MGYG000000196_05082 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2514907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 993365 0 0 0 0 0 0 0 0 0 1669589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLMQSGGGLTIFHGTK MGYG000003351_05246;MGYG000001346_01665;MGYG000001378_04108;MGYG000001345_03248 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,4AP35@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tat pathway signal sequence domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal 1.0 - 1.0 GH109 1.0 - 1.0 - 1.0 MGYG000003351_05246 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 403113 0 0 0 0 0 0 551782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381515 0 0 0 0 0 0 0 0 558849 0 570217 0 0 0 0 0 0 1883878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690383 320939 0 0 0 0 277785 0 0 0 0 749233 0 0 0 0 0 0 794040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308438 418806 0 0 0 0 326741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 606698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLNLDAIHDTVHEMAKDEAR MGYG000000781_01988;MGYG000001306_02407 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1592@1|root,COG1592@2|Bacteria,4NJ7V@976|Bacteroidetes,2FP1G@200643|Bacteroidia,4AKVP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000781_01988 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 56990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211614 0 0 0 329906 0 0 0 0 0 533124 0 0 0 0 0 495181 554501 0 0 0 0 935446 0 0 253924 0 0 0 0 0 0 0 0 0 0 245471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64771 0 0 0 98815 0 0 0 0 0 0 0 0 0 0 0 140552 137229 0 0 0 0 369283 0 0 85208 0 187030 0 0 0 0 0 0 0 0 116973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87755 0 0 0 0 204973 0 0 0 0 99760 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLNPMEPIPADKDVR MGYG000000074_01292 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0612@1|root,COG0612@2|Bacteria,4NFY0@976|Bacteroidetes,2FMCE@200643|Bacteroidia,22UZ7@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Belongs to the peptidase M16 family 1.0 - 1.0 - 1.0 - 1.0 ko:K07263 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_M16,Peptidase_M16_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01292 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07263:pqqL; zinc protease [EC:3.4.24.-] 1.0 none 1.0 0 499030 362929 0 493537 0 461217 330028 0 0 390833 0 0 0 0 364874 0 0 0 300361 0 289849 0 0 391238 416045 338831 0 363499 0 0 358671 359108 0 0 0 279705 0 857652 551547 879706 1238279 827917 711485 801275 1250075 827682 1098911 819341 1030581 496546 1119406 507387 925327 871746 0 1820342 1831333 1183045 826487 0 568395 888218 1081644 964162 0 959889 902568 439956 1059692 963449 0 962282 911328 1130227 639183 371125 469985 0 0 338158 387761 0 0 234917 0 0 510003 0 0 0 0 283417 0 407426 0 330571 448400 0 0 0 0 0 0 0 386749 0 0 352189 0 0 0 0 0 939411 864755 839074 957397 837954 1084765 1228678 1255802 920215 1210723 570266 878756 935900 1013085 1166815 885533 1027148 0 1370378 1039321 1034224 809029 0 749349 1197520 1198339 1210624 0 1079863 608117 724365 841720 777311 0 1043193 978547 1010594 768241 2284435 1567397 2161030 4024401 2479397 2410682 2047335 1879042 2359163 2746314 1705880 1999777 3153465 1511557 2276702 2240182 2809408 0 4208060 3669609 2252746 2194048 0 2645894 2580629 2565944 2347688 0 2655212 3579694 2116830 2053012 1693866 0 2169068 2105747 2991533 2626580 +(Gln->pyro-Glu)QLNTEITR MGYG000000280_01150 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__AM51-8|s__AM51-8 sp003478275|m__MGYG000000280 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,4BWM7@830|Butyrivibrio 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_01150 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLNVVTTQLGVDAK MGYG000000142_02503;MGYG000004733_01558;MGYG000000171_00589;MGYG000000252_00283;MGYG000000201_00498;MGYG000002298_01761;MGYG000000031_02025;MGYG000000212_01933;MGYG000000002_02254 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase delta subunit 1.0 acsD 1.0 - 1.0 2.1.1.245 1.0 ko:K00194 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_02503 0.1111111111111111 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00194:cdhD, acsD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLNVVTTQLGVNAQK MGYG000001338_02426;MGYG000000184_00684;MGYG000002312_01596;MGYG000000213_00150 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase delta subunit 1.0 acsD 1.0 - 1.0 2.1.1.245 1.0 ko:K00194 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02426 0.25 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00194:cdhD, acsD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 914796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150031 594648 0 0 0 0 0 0 0 469479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 847405 518099 0 0 0 0 0 0 0 497037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 583456 898404 907411 0 0 0 0 372508 +(Gln->pyro-Glu)QLPIGKEDDFK MGYG000000077_01356;MGYG000001637_00070;MGYG000000154_02190;MGYG000002528_01099;MGYG000004414_01432;MGYG000000201_03874;MGYG000001338_03374;MGYG000000179_00921;MGYG000000146_01349;MGYG000002492_00343;MGYG000002517_00204;MGYG000001315_01206;MGYG000000262_00029 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia 0.38461538461538464 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 0.9230769230769231 MGYG000000077_01356 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1145272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLPVYGDGMQIR MGYG000001300_00652;MGYG000001255_00155;MGYG000002040_00632;MGYG000003899_00401;MGYG000003166_01976;MGYG000001627_00377;MGYG000003291_01463 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily 1.0 rfbB 1.0 - 1.0 4.2.1.46 1.0 ko:K01710 1.0 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 1.0 M00793 1.0 R06513 1.0 RC00402 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS02615 1.0 GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 GT2 0.8571428571428571 MGYG000001300_00652 0.14285714285714285 dTDP-glucose 4,6-dehydratase. - - dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. 1.0 1.0 1.0 1.0 Streptomycin biosynthesis|Polyketide sugar unit biosynthesis|Acarbose and validamycin biosynthesis|Biosynthesis of vancomycin group antibiotics 1.0 K01710:rfbB, rmlB, rffG; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 445441 0 0 0 0 0 0 0 421644 0 0 0 0 0 0 249849 0 0 0 0 0 0 254617 0 0 0 0 0 0 0 0 0 0 850295 0 0 0 0 635180 0 0 0 0 0 0 0 794877 0 0 0 0 0 0 747860 0 0 0 0 0 0 458683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 357715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374070 0 0 0 0 429092 0 0 0 0 0 0 0 329700 0 0 0 0 0 0 95551 0 0 0 0 0 0 226555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLQALREELDSK MGYG000002834_00586;MGYG000003697_00203 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,2FNI1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002834_00586 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 761618 0 0 0 0 851574 0 0 0 0 894100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLSGKR MGYG000001345_04617;MGYG000003539_00358;MGYG000002534_00332;MGYG000003681_02208;MGYG000002494_02064;MGYG000002506_03025;MGYG000002549_03009;MGYG000000243_01838;MGYG000001489_01493 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,4AMYK@815|Bacteroidaceae 0.5555555555555556 976|Bacteroidetes 0.6666666666666666 H 0.6666666666666666 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 0.6666666666666666 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 0.6666666666666666 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_04617 0.1111111111111111 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 1414582 0 4482393 0 2941063 1727217 2118961 0 2211522 0 2548022 0 3384367 0 1656981 3221659 2040318 0 0 1817519 0 2188387 0 1956515 1769395 2108775 0 0 0 0 3571714 0 7776452 0 1999132 0 2311714 6769279 1409453 0 1593284 0 2191059 1211199 1686372 0 1165818 0 3678816 0 4876998 0 1860263 3344816 1720032 0 0 1481069 0 1295469 0 971557 1528830 2031736 0 0 0 0 1265113 0 963435 0 1885245 0 1480133 1527698 756639 0 1789610 0 1836423 1437009 835983 0 1386397 0 1779117 0 2627478 0 1372786 2150825 908753 0 0 1356619 0 1789555 0 335284 1307828 1398320 0 0 0 0 1057809 0 1527922 0 1626185 0 1273959 1211988 826576 0 427370 0 642165 461284 807517 0 789924 0 915867 0 551401 0 362858 913401 643810 0 0 644122 0 589536 0 321534 758377 810412 0 0 0 0 302896 0 489131 0 965095 0 868954 373935 1022468 0 972739 0 1870360 1174736 1469060 0 1545366 0 2791752 0 2162040 0 742082 971283 972050 0 0 862836 0 1610534 0 2478911 1648373 1643844 0 0 0 0 1901202 0 1399368 0 4066534 0 2998604 1577807 +(Gln->pyro-Glu)QLSLDRDPHGNVQVSLIETEK MGYG000000042_02105;MGYG000001306_00885;MGYG000000138_03763;MGYG000001346_02908;MGYG000000236_04310;MGYG000002033_03229;MGYG000003693_02493;MGYG000003681_01737;MGYG000003701_00980;MGYG000000243_02424;MGYG000003363_03107;MGYG000004479_02550;MGYG000002438_03062;MGYG000000043_01357 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 0.7142857142857143 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 0.9285714285714286 MGYG000000042_02105 0.07142857142857142 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 932891 0 0 0 0 0 0 0 448900 0 475544 0 0 594107 0 372945 0 0 287957 0 523738 0 0 0 0 558662 0 448551 0 0 1092276 0 0 327063 0 891900 0 0 397349 0 0 0 0 0 0 0 504650 0 269011 0 0 531567 0 0 0 0 0 0 1853720 0 0 0 0 1338500 0 0 0 0 0 0 0 0 0 0 0 0 286930 0 0 0 0 0 0 0 992630 0 591918 0 0 766362 0 721331 0 0 671300 0 598027 0 0 0 0 684864 0 368179 0 0 238740 0 0 388286 0 613198 0 0 0 0 0 0 0 0 0 0 180675 0 295774 0 0 0 0 0 0 0 523782 0 665480 0 0 0 0 0 0 296221 0 0 0 0 0 295135 0 0 0 0 0 0 0 0 0 0 0 0 1011051 0 439167 0 0 383917 0 688029 0 0 1016072 0 614847 0 0 0 0 512117 0 1273559 0 0 0 0 0 147008 0 0 +(Gln->pyro-Glu)QLTADELAAAPAQTK MGYG000002274_02671;MGYG000000022_01634;MGYG000002040_01920;MGYG000002545_01451;MGYG000000573_01090;MGYG000003899_01586;MGYG000003166_00684 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002274_02671 0.14285714285714285 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1081285 0 0 0 0 321983 0 0 0 0 314244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228682 0 0 0 0 176862 0 0 0 0 322609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217361 0 0 0 0 266629 0 0 0 0 479803 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 717294 0 0 0 0 644639 0 0 0 0 827046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252582 0 0 0 0 447692 0 0 0 0 540299 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLTAELQR MGYG000000013_00131;MGYG000000029_03029;MGYG000002549_03516;MGYG000003351_03212;MGYG000000054_01820;MGYG000001378_02728 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_00131 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 0 0 0 161341 0 0 0 0 0 0 563264 361668 0 373970 0 0 200912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286193 0 0 0 0 0 283441 0 0 0 0 0 0 651431 347790 0 333964 0 0 233453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268030 0 0 0 0 0 113766 0 0 0 0 0 0 137451 305877 0 236108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261667 0 0 0 0 0 437541 0 0 0 0 0 0 1183211 419714 0 329576 0 0 394177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454750 0 0 0 0 0 381862 0 0 0 0 0 0 243821 117930 0 216607 0 0 294525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128414 0 0 +(Gln->pyro-Glu)QLTEAIKR MGYG000002926_01578;MGYG000004831_00136;MGYG000001500_00622;MGYG000003819_01324;MGYG000004482_00128;MGYG000002156_01981;MGYG000001616_02088;MGYG000002116_01091;MGYG000002103_00765;MGYG000003589_00969;MGYG000004784_01496;MGYG000004475_00688;MGYG000004276_01515;MGYG000001576_00629;MGYG000002720_00236;MGYG000002794_00964;MGYG000000099_01480;MGYG000004628_02333 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,2N7K8@216572|Oscillospiraceae 0.5555555555555556 186801|Clostridia 1.0 J 0.7777777777777778 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit 0.7777777777777778 rpsR 0.7777777777777778 - 1.0 - 1.0 ko:K02963 0.7777777777777778 ko03010,map03010 0.7777777777777778 M00178 0.7777777777777778 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.7777777777777778 - 1.0 - 1.0 - 1.0 Ribosomal_S18 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_01578 0.05555555555555555 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.7777777777777778 K02963:RP-S18, MRPS18, rpsR; small subunit ribosomal protein S18 0.7777777777777778 none 1.0 650847 0 0 0 0 0 0 462134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640779 0 0 0 0 0 0 0 574408 0 0 551925 0 1007719 0 0 0 0 0 0 814810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 665874 0 0 0 0 0 0 0 900224 0 0 710693 0 1063989 0 0 0 0 0 0 1131267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 950329 0 0 0 0 0 0 0 1260173 0 0 1294289 0 663453 0 0 0 0 0 0 726341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632959 0 0 0 0 0 0 0 999140 0 0 583315 0 676928 0 0 0 0 0 0 788448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460876 0 0 0 0 0 0 0 613479 0 0 601243 0 +(Gln->pyro-Glu)QLTFEQSLR MGYG000002298_01714;MGYG000000312_01698;MGYG000000142_02312;MGYG000000212_00041;MGYG000000200_01186;MGYG000004839_01157;MGYG000000242_00809;MGYG000000140_00016;MGYG000002286_02635;MGYG000000031_02755;MGYG000002312_00716;MGYG000003702_01337;MGYG000001338_00212;MGYG000000201_03106;MGYG000004735_01618 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3XZ1G@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 8.87 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP_cyclohyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_01714 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLTGKEPFK MGYG000000077_00522;MGYG000002528_00169;MGYG000000262_01374;MGYG000000080_02990 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,25VH9@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00522 0.25 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225162 0 0 0 0 0 0 0 0 0 0 0 1005910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438273 0 0 0 0 0 0 0 0 0 0 0 628920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 952513 0 0 0 0 0 0 0 0 0 0 0 271510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1144508 0 0 0 0 0 0 0 0 0 0 0 1529680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1050038 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLTGKEPSK MGYG000003012_00270;MGYG000002278_00654;MGYG000000123_02326;MGYG000002528_00994;MGYG000000489_01891;MGYG000000200_01023;MGYG000000255_01223;MGYG000000002_00433;MGYG000000181_00382;MGYG000004869_03374;MGYG000000171_01795;MGYG000000152_05170;MGYG000000281_00071;MGYG000000179_03775;MGYG000001689_04245;MGYG000000245_00866;MGYG000001531_01900;MGYG000000271_02474;MGYG000000142_01918;MGYG000004733_01142;MGYG000004087_01928;MGYG000000202_02200;MGYG000002256_00937;MGYG000001065_01063;MGYG000000233_02915;MGYG000000153_02121;MGYG000002974_00091;MGYG000002517_00989;MGYG000003821_01669;MGYG000000133_02344;MGYG000004762_01166;MGYG000004271_00836;MGYG000000198_01270;MGYG000003422_00551;MGYG000000028_00147 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.37142857142857144 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003012_00270 0.02857142857142857 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 1651361 1180920 810144 1272828 1759518 1766360 855370 1295382 953014 1374967 1332823 1423513 1523804 1732482 1637958 1509387 1285450 1599526 1360655 1938929 1947052 1886107 1119127 1019832 1193077 1307809 1444089 1236042 1292289 1670634 730277 1228835 832044 2086707 1376731 1258732 1128627 786261 816577 2160283 809932 138087 768018 827537 906512 860465 0 809111 520793 0 0 845515 896303 467223 0 656190 782414 854035 977900 391237 664605 963482 943040 655756 851179 823464 1347290 1245819 1910045 1061698 1134809 1561060 1244059 597732 811295 724922 1440898 2037068 929283 1555471 450792 590151 1090767 1363559 1124517 1384935 584639 1034294 601751 1384863 1853368 1023693 1659228 0 1166949 1408524 1390827 1255184 479714 658336 1233151 1537205 1625777 363321 1204765 1936658 801449 1380546 933485 1857293 1269553 1299650 1544152 758925 4662310 2775671 1746334 5220853 2769022 1822536 2157423 4187945 3092928 2928705 2634582 1869668 1701022 4701458 3634997 2633160 4184106 576390 3324431 3322715 1611740 1732735 203564 1325240 3427253 2958301 7251730 1190252 3226707 3537350 2676094 2454957 2288507 2795932 4201445 4387596 3605286 2115199 2345830 2153127 2352029 1327479 2308164 2318972 1314308 1982498 3348758 3435780 2859378 2897201 1925748 1401125 2934212 3393950 2599102 596995 3152590 2444121 2221152 2479657 1315141 3267718 2658397 3253349 2430708 863458 1232149 2414742 1976188 1971239 2499342 1355686 1424358 1499938 3465209 2603157 +(Gln->pyro-Glu)QLTKEDGTTPK MGYG000000074_00712 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,22U9R@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal protein S1 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00712 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 0 0 282684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450405 0 0 0 0 145611 0 427841 421792 606463 0 117255 306924 0 370556 199398 0 0 0 237547 0 177336 0 0 227957 389406 328714 0 0 0 112073 0 0 0 543905 333431 405234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322172 0 406752 0 0 0 0 436255 225562 0 0 0 374634 0 0 0 0 287797 295502 335414 0 0 0 0 0 0 0 322710 171322 0 0 1523765 0 0 0 0 1676224 1725663 1352743 1763817 1807847 0 1442906 2324052 0 1674309 1615464 1570862 0 0 2165856 0 1252032 0 1408459 1646968 2459898 1297726 0 0 0 1365612 0 0 0 1891304 2276558 2650588 0 +(Gln->pyro-Glu)QLTLDRDPHGNVQVSLIETEK MGYG000004876_02004;MGYG000002281_01665;MGYG000004797_01062;MGYG000002181_00899;MGYG000001780_01920;MGYG000001313_01096;MGYG000002455_02781;MGYG000002549_01269;MGYG000000054_01445;MGYG000000196_00779;MGYG000004464_00923 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 0.8181818181818182 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 MGYG000004876_02004 0.09090909090909091 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 542322 0 0 0 602283 479016 0 440318 618520 0 582209 380418 924316 747990 515420 969835 0 581744 358483 459664 0 499951 580809 527753 0 703556 859154 755117 0 499205 0 348949 0 0 0 773916 643872 0 659442 0 0 0 1059897 839157 0 1099047 832343 0 1504958 1040197 1744459 979849 1052121 1898955 0 639920 816117 925335 0 904016 647077 606963 0 1102873 989967 774633 0 1209714 0 1392983 0 0 0 784701 745606 0 335261 0 0 0 721845 506040 0 375731 252114 0 609072 616634 218266 517871 478328 664355 0 982328 306498 424199 0 238663 738166 623590 0 205921 416907 935994 0 672349 0 0 0 0 0 468572 487012 0 345615 0 0 0 434221 325212 0 116708 253718 0 331347 388302 444288 486007 329460 436674 0 0 390404 357362 0 353117 0 0 0 344899 0 0 0 364605 0 441070 0 0 0 460494 260083 0 733543 0 0 0 1007201 682089 0 825694 766378 0 382462 0 1523359 423616 526077 1368052 0 1334658 775486 1173533 0 562356 1066795 607012 0 713419 420843 1121934 0 1268710 0 529930 0 0 0 659713 606341 0 +(Gln->pyro-Glu)QLTPHPWDALDANLQVGDKVK MGYG000000243_01228;MGYG000002478_02960 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01228 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 1606649 1603416 3035558 0 3044648 1668474 0 1764825 1601633 1615564 1312304 1552570 3872269 1329350 1390329 2647921 0 1078655 1571258 1253337 1724836 1327614 1383607 1395757 1400749 1636978 2035544 1831361 1504937 2226963 2133298 1861366 3738843 1477349 1876886 0 1520306 2756778 757382 828766 1159903 0 2864053 1217512 0 1504679 1113430 1482456 1654976 1594514 4689154 1372873 1629099 3561099 0 674720 1476600 173101 1144989 1303527 1301378 853897 1517263 1555017 1467740 925355 1056157 1910137 717781 1486557 985190 857411 1428698 0 984997 1008982 520977 388434 442209 0 1235028 788578 0 377416 598321 377683 678232 737996 2274622 616646 575250 1301972 0 1242698 532038 462515 533690 550928 1098539 757974 517995 696961 348748 1193379 801475 512118 781035 335128 405527 335273 758666 0 482965 574179 0 0 0 0 0 0 0 0 0 0 0 0 199006 0 0 152377 0 0 73195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231259 0 0 82331 577401 0 335801 0 2023078 502042 0 443496 265422 250162 0 390830 7909802 1025514 392961 1760175 0 1015553 604196 984785 361536 0 1552627 2526529 870476 1448220 1818861 4229418 0 720012 177616 0 839534 94874 0 0 0 0 +(Gln->pyro-Glu)QLTPHPWDALDENLK MGYG000001630_00344;MGYG000000707_00011;MGYG000002293_00147 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001630_00344 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608867 0 0 0 0 0 0 477816 0 0 0 0 588360 0 0 0 0 449852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLTPHPWDALDPNLK MGYG000002218_00698;MGYG000003681_00897;MGYG000003697_01824;MGYG000002080_02027;MGYG000004456_02407;MGYG000004495_00381;MGYG000001783_01031;MGYG000000044_01026;MGYG000001313_02488;MGYG000003693_01627;MGYG000003460_01250 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 0.36363636363636365 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002218_00698 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363959 0 0 0 0 168776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724553 0 0 0 0 0 0 2833835 0 0 0 0 3080841 0 0 0 0 2474604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4245208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3236144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLTPHPWDALDSEIK MGYG000001806_00025 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900553965|m__MGYG000001806 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001806_00025 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1715599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLTPHPWDALDSELK MGYG000003493_01806;MGYG000003470_00203 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003493_01806 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1448027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLTPHPWDALDTDLK MGYG000003312_01455;MGYG000000196_00547;MGYG000001378_02385;MGYG000002281_02540 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003312_01455 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 680509 1493602 0 0 868046 0 0 0 0 0 0 0 0 0 0 0 407926 0 691447 0 0 0 0 0 0 0 920219 0 0 0 0 0 0 0 0 0 0 0 1055410 607696 0 0 928209 0 0 0 0 0 0 0 0 0 0 0 704279 0 456529 0 0 0 0 0 0 0 741310 0 0 0 0 0 0 0 0 0 0 0 296415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257077 0 144301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLTPHPWDALDTNLK MGYG000002438_01919 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,22WN9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01919 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310536 0 0 0 0 0 0 0 0 0 0 0 0 292364 0 0 0 0 0 0 556700 0 0 0 0 0 0 0 0 528121 0 0 0 0 0 0 0 0 521860 0 0 0 0 0 0 0 0 0 0 0 0 543783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317489 0 0 0 0 0 0 0 0 827388 0 0 0 0 0 0 0 0 328345 0 0 0 0 0 0 0 0 0 0 0 0 749695 0 0 0 0 0 0 817145 0 0 0 0 0 0 0 0 1220894 0 0 0 0 0 0 0 0 1244260 0 705884 0 0 0 0 0 0 +(Gln->pyro-Glu)QLTPHPWDSLDPNLK MGYG000000696_00589;MGYG000001750_01904;MGYG000000355_01785;MGYG000001306_01408;MGYG000001789_00306;MGYG000004622_00252 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,4ANYG@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000696_00589 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 921565 0 0 0 0 1390939 0 0 0 0 1493955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 606890 0 0 0 0 354937 0 0 0 0 446592 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLTPHPWEALDQNLK MGYG000000074_00712 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,22U9R@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal protein S1 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00712 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180246 0 0 0 302891 244417 0 0 298976 0 0 0 0 0 0 334389 242484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361057 0 0 0 0 0 0 0 219391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104707 717481 0 617396 881402 1137250 1035775 0 824028 851719 868442 0 650596 0 0 612193 815288 659729 0 1476814 1196130 0 722906 0 571178 1017535 1107361 0 0 0 1233180 0 0 439904 0 968304 0 1180486 704194 +(Gln->pyro-Glu)QLVAEETTK MGYG000000484_00676;MGYG000001496_00483;MGYG000004039_02305;MGYG000001710_01296;MGYG000000217_01905;MGYG000001319_00742;MGYG000001602_01548;MGYG000001311_02470;MGYG000000198_00463;MGYG000000205_01169;MGYG000001531_01705;MGYG000004891_01762;MGYG000000255_00822;MGYG000000233_00090;MGYG000001065_00813;MGYG000000179_05120;MGYG000001622_02526;MGYG000004296_00910;MGYG000001315_00697 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,220V7@1506553|Lachnoclostridium 0.42105263157894735 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000484_00676 0.05263157894736842 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04078:groES, HSPE1; chaperonin GroES 1.0 none 1.0 1020661 0 0 207994 0 0 285981 0 415948 0 0 0 0 0 397322 0 230822 0 386723 863205 367036 0 0 0 0 412223 586955 0 0 546199 0 325738 0 566629 469540 0 536026 0 0 0 0 0 0 0 386598 350035 505106 0 0 312673 0 0 576058 0 211828 0 407089 0 536795 0 0 0 0 0 409182 0 0 138747 0 0 0 467411 330075 0 332078 411699 395613 0 410114 337492 0 387797 269477 0 551242 0 0 427740 0 0 431212 0 373946 0 261256 493644 433026 559870 0 369218 0 405089 359615 0 0 597117 144670 0 219231 209560 164377 0 369486 281937 380093 0 537816 632585 0 314839 153442 260350 337000 0 0 384190 0 0 296136 0 0 0 179075 486296 0 338111 0 184026 0 464694 228123 0 0 477316 338484 607989 291333 253473 382254 0 265461 586029 1570735 0 1227106 2366781 0 1232880 1576848 936238 2324681 0 0 1535565 0 0 1905922 0 2225521 0 1835145 2333244 1282479 1409521 0 1060943 0 2085241 1547579 0 0 2109356 1207946 1264373 1082734 1834792 825582 0 2258854 1326086 +(Gln->pyro-Glu)QLVEKEK MGYG000003697_00203 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,2FNI1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_00203 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2871076 0 0 0 0 1779207 0 0 0 0 2645384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 661127 0 0 0 0 1544407 0 0 0 0 875619 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLVGGAGEDTILAR MGYG000001346_02810;MGYG000000224_00999;MGYG000002717_02505;MGYG000000196_01170;MGYG000001337_01654;MGYG000002561_03042;MGYG000001780_02594;MGYG000003351_01171;MGYG000000144_01411;MGYG000004748_03340;MGYG000003312_00309;MGYG000003681_01088;MGYG000000098_00198;MGYG000000013_00875;MGYG000000117_01899;MGYG000002549_00836;MGYG000001378_02596;MGYG000001345_01669;MGYG000002291_00827;MGYG000000105_02956;MGYG000002455_02988;MGYG000001313_02601;MGYG000000054_03643;MGYG000003252_05864;MGYG000000243_01379;MGYG000002171_02922;MGYG000004899_03911;MGYG000003282_01306;MGYG000000029_01582;MGYG000002275_00273 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG4864@1|root,COG4864@2|Bacteria,4NGG6@976|Bacteroidetes,2FPNC@200643|Bacteroidia,4ANG3@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 S 0.9333333333333333 UPF0365 protein 0.9333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 YdfA_immunity 0.9333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_02810 0.03333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232605 0 0 0 0 385039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361087 0 0 0 0 396521 0 0 0 0 370737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490600 0 0 0 0 365694 0 0 0 0 722355 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLVGHK MGYG000004797_01999;MGYG000001306_02686;MGYG000002293_00480;MGYG000003697_01442 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,2FMRC@200643|Bacteroidia,4AMR2@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01999 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 259092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209261 0 0 0 0 878098 0 0 0 0 1189762 0 0 0 0 1613646 0 0 0 0 1906803 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1183165 0 0 0 0 2981818 0 0 0 0 3336276 0 0 0 0 994161 0 0 0 0 991196 0 0 1044224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 933677 0 0 0 0 1073292 0 0 0 0 1220294 0 0 0 0 0 0 0 0 0 471022 0 0 4314992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2394638 0 0 0 0 2005355 0 0 0 0 3239881 0 0 0 0 3524695 0 0 0 0 3486376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLVYSALNIK MGYG000000195_01573;MGYG000004866_01550;MGYG000003921_01192;MGYG000002651_00836;MGYG000003937_01091;MGYG000001300_00295;MGYG000003899_01136;MGYG000000022_01324;MGYG000004679_00524;MGYG000003166_01334;MGYG000002274_00044;MGYG000002545_00548;MGYG000000084_00623;MGYG000002059_01523;MGYG000000039_00171;MGYG000002040_01715;MGYG000001255_01114;MGYG000001761_00369 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000195_01573 0.05555555555555555 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 968040 1532506 2076875 1150772 361832 1012777 903493 814241 957172 1118764 1093197 982415 1934012 1102438 0 1503449 1320049 572646 1381740 1176915 361768 1215353 735119 936652 935823 930412 1194888 894572 0 854951 1127616 903039 1957344 1551150 752283 385103 956639 1337177 1745152 3907247 3584256 2618710 2716273 4182895 3718442 1527595 2591036 911968 2215997 3416928 2667075 2742339 2664717 2016884 3612195 1380891 3480444 3081140 1476238 2949915 1872287 3786588 3709326 2986443 2743138 1604670 0 2420823 4560472 3778076 3139933 2238304 837945 2048890 2046759 3003024 114544 493747 216520 72062 386415 146407 251273 248146 208822 203288 330521 416301 319943 323096 98032 390014 277184 1141553 190194 207951 488677 129128 1162917 344818 201341 189884 199824 1452079 0 457245 367993 282971 73261 290182 224425 181051 222835 177339 409586 323808 568109 307946 385629 331955 577920 182615 428222 234353 373029 1032866 418359 388586 386726 270639 310870 0 409960 183730 775098 231621 0 0 543382 490208 399648 0 0 384753 316155 619220 465561 743069 63292 281334 448321 277003 0 0 630953 71610 124529 126157 247084 294377 0 0 0 546466 0 192978 0 248662 0 999590 136472 0 292211 77374 1114319 212619 234421 0 106517 1488330 0 224890 252572 131368 275592 0 0 232335 0 0 +(Gln->pyro-Glu)QLWWGHR MGYG000003546_00525;MGYG000003554_01593;MGYG000002963_04124;MGYG000002552_01119;MGYG000002549_00666;MGYG000002212_01054;MGYG000001599_01345;MGYG000002485_01178;MGYG000000028_00919;MGYG000000140_01107;MGYG000001770_02254;MGYG000000142_02094;MGYG000003469_00855;MGYG000000249_01473;MGYG000000245_01734;MGYG000000301_00138;MGYG000000138_02053;MGYG000004727_01310;MGYG000002517_00674;MGYG000000184_01152;MGYG000004762_01478;MGYG000000233_00075;MGYG000000271_01901;MGYG000004797_03994;MGYG000001164_02046;MGYG000003922_02194;MGYG000004642_00522;MGYG000000355_00463;MGYG000002050_00390;MGYG000002281_02548;MGYG000000031_03328;MGYG000001447_00042;MGYG000002312_02297;MGYG000002506_03988;MGYG000003363_00444;MGYG000002293_01163;MGYG000000201_00944;MGYG000001688_02000;MGYG000004317_00021;MGYG000002478_02951;MGYG000000222_00614;MGYG000000187_00532;MGYG000004763_01971;MGYG000002234_00068;MGYG000000212_03026;MGYG000002492_02349;MGYG000000213_00326;MGYG000000127_03267;MGYG000002756_00331;MGYG000001337_01539;MGYG000000002_00399;MGYG000002494_02798;MGYG000002985_00329;MGYG000001496_02122;MGYG000002033_00874;MGYG000001306_02859;MGYG000000258_00349;MGYG000002445_00464;MGYG000003697_02045;MGYG000002969_00818;MGYG000002535_03704;MGYG000002247_00836;MGYG000004893_01367;MGYG000002534_04274;MGYG000000262_01172;MGYG000003266_01529;MGYG000001543_01603;MGYG000002218_01736;MGYG000000909_02211;MGYG000003351_04957;MGYG000002528_02643;MGYG000002025_02287;MGYG000004828_00571;MGYG000000562_01100;MGYG000001714_01373;MGYG000002286_01614;MGYG000002737_01862;MGYG000002603_00589;MGYG000001789_02031;MGYG000001698_02715;MGYG000003372_04217;MGYG000002515_04203;MGYG000000076_01416;MGYG000000243_00147;MGYG000002717_01948;MGYG000000133_00022;MGYG000001338_02829;MGYG000001781_02124;MGYG000000038_00666;MGYG000004823_02266;MGYG000001661_01338;MGYG000001707_01441;MGYG000002298_00234;MGYG000004876_03015;MGYG000000312_01562 domain d__Bacteria 1.0 COG0525@1|root,COG0525@2|Bacteria,4NETB@976|Bacteroidetes,2FPJG@200643|Bacteroidia,4AKPX@815|Bacteroidaceae 0.22105263157894736 186801|Clostridia 0.5368421052631579 J 1.0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner 1.0 valS 1.0 - 0.5684210526315789 6.1.1.9 1.0 ko:K01873 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03665 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 0.9368421052631579 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 0.6631578947368421 - 1.0 - 1.0 - 1.0 GH5_11 1.0 MGYG000003546_00525 0.010526315789473684 valine--tRNA ligase. valyl-tRNA synthetase. - ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01873:VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9] 1.0 none 1.0 364034 514581 392219 403351 0 443716 0 0 0 485708 0 369641 542461 0 97119 0 0 0 0 0 0 334470 0 330020 0 330778 0 0 409204 455834 0 374503 472046 0 431742 0 297384 411939 480025 655727 561955 538340 0 833483 0 0 0 792057 0 643660 685102 0 484709 0 0 0 0 0 0 697005 0 738416 0 630590 0 0 528924 632285 0 617695 541153 0 508136 0 459565 569761 468888 370960 578114 538341 0 533340 0 0 0 384563 0 626878 583475 0 516687 0 0 0 0 0 0 728362 0 420806 0 442122 0 0 589222 499433 0 667190 699592 0 613267 0 541059 483563 374531 522051 488357 411579 0 561003 0 0 0 492510 0 421631 645583 0 475788 0 0 0 0 0 0 114916 0 62572 0 472076 0 0 188210 565507 0 686795 69973 0 599711 0 418824 547068 640829 596650 537326 710731 0 645007 0 0 0 667831 0 698912 555632 0 762560 0 0 0 0 0 0 679877 0 538115 0 608279 0 0 987948 716164 0 653484 593873 0 677114 0 718161 746035 +(Gln->pyro-Glu)QLYGESEGKDGK MGYG000000138_02259;MGYG000001489_02765;MGYG000000080_01997;MGYG000002218_01253;MGYG000003425_01378;MGYG000002478_04548;MGYG000002438_00429;MGYG000004797_02953;MGYG000004885_00824 domain d__Bacteria 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,22VVH@171551|Porphyromonadaceae 0.4444444444444444 976|Bacteroidetes 0.7777777777777778 G 1.0 Belongs to the GPI family 0.8888888888888888 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000138_02259 0.1111111111111111 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 391912 588946 516668 0 694242 875689 473778 0 418410 479821 0 631111 941314 0 0 917641 643203 758303 313193 0 660617 614692 585504 617899 0 423089 0 744343 461610 605064 557616 916085 445977 327729 641080 446371 625995 382046 497008 731645 575765 0 621330 262581 524655 0 517076 489344 0 382233 689950 0 0 552478 390811 328078 1162705 0 587829 233872 546674 504586 0 491650 0 475473 439138 466701 552519 546905 418320 530209 623141 583393 517495 443651 467302 311791 280065 0 414754 295452 387946 0 375949 723428 0 309266 416807 0 0 580790 588343 643257 2147959 0 635129 0 510693 592079 0 503249 0 512008 296846 277034 567459 876751 308072 169603 767175 331085 601410 298827 317740 284600 325715 0 503773 1016584 0 0 358557 393364 0 264595 565547 0 0 305896 297828 0 293304 0 581532 706004 0 237715 0 424712 0 0 437236 431542 239781 316321 429145 0 481939 261133 169476 315003 426492 411804 503286 0 769190 836994 546325 0 691752 397358 0 889007 662571 0 0 569049 720689 1009393 673221 0 961451 582075 1011660 482228 0 783779 0 957824 1232241 940418 667148 911915 389494 556332 872545 902704 632284 679305 +(Gln->pyro-Glu)QLYGESEGKDQK MGYG000002603_00166;MGYG000003697_00356;MGYG000001770_01372;MGYG000004735_01120;MGYG000003012_00855;MGYG000002445_02761;MGYG000002966_02852;MGYG000001056_00808;MGYG000004689_01366;MGYG000002293_00785;MGYG000000287_02964;MGYG000000806_00684;MGYG000002025_01407;MGYG000002960_01371;MGYG000000133_02455 domain d__Bacteria 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia 0.4 186801|Clostridia 0.6 G 1.0 Belongs to the GPI family 0.6666666666666666 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002603_00166 0.06666666666666667 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230059 0 0 0 0 0 0 0 0 0 189452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271412 599116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1159044 0 861798 0 0 0 0 0 963567 0 0 0 0 958424 0 1877942 0 0 0 1098852 2161223 0 805766 0 0 0 0 0 0 0 1015300 0 0 0 0 0 0 0 812594 1324576 350225 0 908197 0 0 0 0 0 0 0 0 588611 577035 0 0 0 922156 0 0 0 728351 1135529 620872 0 791590 0 0 951112 0 947686 0 1173325 0 687412 +(Gln->pyro-Glu)QLYGESEGKENK MGYG000002455_01614;MGYG000001780_00268;MGYG000004876_01420;MGYG000001346_00849;MGYG000003681_00158;MGYG000002171_00278;MGYG000004899_01388;MGYG000000243_00070;MGYG000001313_03153 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,4AKGG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_01614 0.1111111111111111 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 588769 611692 1392794 511252 1122223 748012 473243 608340 503193 609048 649089 543100 992516 733874 853483 876389 0 951044 585511 594177 0 493933 551872 501982 548133 619158 473705 644500 500935 551978 657385 0 1444738 659088 550022 436041 687116 1424438 494661 367474 460020 356215 468995 424149 347616 430883 496434 524599 424876 624438 401687 411293 377424 334759 0 289498 433396 293031 0 374273 291953 295406 204880 476799 410437 372378 347547 552053 238330 0 359664 458522 621795 472499 446516 505329 749576 760743 905990 589414 1011896 893709 888630 907236 1005660 772079 977392 627602 832142 922663 789343 799087 0 1229633 839233 597682 0 725514 1064661 800981 767488 588384 792825 1105805 832860 681162 813327 0 605797 732321 912857 900443 688965 804973 556682 726183 0 624984 0 1196962 755019 723843 742562 736118 0 966028 935359 694583 717470 0 0 0 601278 562959 0 529783 0 991169 0 0 701777 2343724 675463 674775 815753 0 0 799591 821680 801947 677625 1199680 555189 281434 0 298988 443575 580733 0 183120 678182 991734 1490517 1049481 453569 1046271 630354 0 0 699728 847583 421545 0 581049 565862 503673 0 0 0 664424 0 373752 743293 0 1417589 0 643409 581470 534540 0 +(Gln->pyro-Glu)QLYIHR MGYG000002202_02071;MGYG000000177_01062;MGYG000000146_02457;MGYG000000262_00216 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,27VFV@189330|Dorea 0.5 186801|Clostridia 1.0 QT 1.0 PucR C-terminal helix-turn-helix domain 0.75 cdaR_3 1.0 - 1.0 - 1.0 ko:K02647 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 HTH_30 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002202_02071 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02647:cdaR; carbohydrate diacid regulator 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1166877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 970883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1761648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1290853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1006408 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLYQHMAK MGYG000002534_00492;MGYG000002494_01841;MGYG000002515_03110 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3105@1|root,COG3105@2|Bacteria,1RE90@1224|Proteobacteria,1S3S2@1236|Gammaproteobacteria,3XPIB@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 oxidoreductase activity 1.0 yhcB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 1.0 - 1.0 ko:K09908 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF1043 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002534_00492 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K09908:K09908; uncharacterized protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 223306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 863410 0 0 1092276 0 0 0 968131 0 0 0 878445 0 0 0 0 1156784 0 0 1087320 0 971742 0 0 0 0 0 0 0 0 785778 0 0 713482 0 568940 0 0 281834 0 0 484548 0 0 0 264580 0 0 0 227861 0 0 0 0 365681 0 0 412452 0 331305 0 0 0 0 0 0 0 0 174417 0 0 289796 0 203305 0 0 485940 0 0 0 0 0 0 698392 0 0 0 510190 0 0 0 0 367641 0 0 886409 0 404284 0 0 0 0 0 0 0 0 634711 0 0 943298 0 875068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLYSAGIPK MGYG000004732_00520 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__|m__MGYG000004732 1.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 1.0 rpsC 1.0 - 1.0 - 1.0 ko:K02982 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004732_00520 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02982:RP-S3, rpsC; small subunit ribosomal protein S3 1.0 none 1.0 0 0 0 0 0 0 0 0 0 366984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1289141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QLYVDHTK MGYG000000133_00237;MGYG000000216_00421 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 0.5 186801|Clostridia 1.0 M 0.5 Cobalt chelatase (CbiK) 0.5 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00237 0.5 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 0 0 0 121846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 108810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15777839 0 16434509 23014774 0 9326026 0 9077627 11188413 20433567 18897209 14765260 9356411 23031789 16538493 11899858 14932748 0 15123664 6325371 18341275 0 0 6848585 11286371 21930313 17145636 0 23327450 5096063 12529497 19739976 20330797 19376373 6572063 14375461 12286927 10869373 +(Gln->pyro-Glu)QM(Oxidation)EVLEAIK MGYG000004785_01065;MGYG000000142_02501;MGYG000000200_00066;MGYG000002312_01594;MGYG000000002_02252;MGYG000003409_00273;MGYG000000216_02769;MGYG000003821_01555;MGYG000001338_02424;MGYG000002966_01692;MGYG000000184_00686;MGYG000000201_00500;MGYG000000263_02678;MGYG000001602_02146;MGYG000000806_02369;MGYG000000050_00432;MGYG000000743_01335;MGYG000000213_00152 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3XZQ5@572511|Blautia 0.7777777777777778 186801|Clostridia 1.0 E 0.8888888888888888 Psort location Cytoplasmic, score 8.87 0.7777777777777778 acsE 0.8888888888888888 - 1.0 2.1.1.258 0.8888888888888888 ko:K15023 0.8888888888888888 ko00720,ko01120,ko01200,map00720,map01120,map01200 0.8888888888888888 M00377 0.8888888888888888 R02289,R10243 0.8888888888888888 RC00004,RC00113,RC01144,RC02871,RC02977 0.8888888888888888 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pterin_bind 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004785_01065 0.05555555555555555 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the N(5) group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein.-!-Involved, together with EC 1.2.7.4 and EC 2.3.1.169, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea. (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein] = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+). 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 0.8888888888888888 K15023:acsE; 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258] 0.8888888888888888 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QM(Oxidation)FDAEGYEVVAINDLTSPK MGYG000002126_00535;MGYG000000022_00437;MGYG000001255_00370;MGYG000000371_00136;MGYG000002619_02023;MGYG000002641_00563;MGYG000000217_00275;MGYG000001300_02008 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.875 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.875 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002126_00535 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13949069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QM(Oxidation)FDAEGYQVVAINDLTSPK MGYG000002098_00013 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01|s__|m__MGYG000002098 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002098_00013 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20429713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QM(Oxidation)FGAEGYEVVAINDLTSPK MGYG000000280_02459;MGYG000000038_02185;MGYG000003582_01256;MGYG000001607_01815;MGYG000000204_00778;MGYG000001310_02090;MGYG000004740_01468;MGYG000001319_00348;MGYG000000187_02264;MGYG000000262_01195;MGYG000002517_01026;MGYG000001299_00204;MGYG000000251_00555;MGYG000002528_00367;MGYG000003450_00202;MGYG000002279_00557;MGYG000000398_00286;MGYG000002025_02240;MGYG000000164_00800;MGYG000000271_03250;MGYG000004271_00554;MGYG000000562_01218;MGYG000001421_02311;MGYG000004317_00142;MGYG000000404_00344;MGYG000004735_01946;MGYG000000153_00303;MGYG000002492_01379;MGYG000001652_01009;MGYG000000489_00503;MGYG000004593_01977 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.41935483870967744 186801|Clostridia 0.9354838709677419 G 0.6129032258064516 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5161290322580645 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_02459 0.03225806451612903 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 267837 0 0 0 0 0 0 0 0 253954 0 0 0 0 0 0 0 0 298831 0 0 0 0 0 0 294766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177581 0 246217 0 0 0 0 0 0 0 0 217215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234934 0 0 0 0 0 0 0 0 0 0 283613 0 0 0 0 0 0 0 0 0 0 90262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34635317 0 0 0 0 0 0 0 0 25129960 0 0 0 0 0 0 0 0 25803920 0 0 0 0 0 0 26115611 0 0 0 0 0 0 0 0 0 0 40385228 0 +(Gln->pyro-Glu)QM(Oxidation)LDDFSRR MGYG000000200_02976;MGYG000001338_00486;MGYG000000212_03361;MGYG000000171_01373 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3XYJC@572511|Blautia 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000200_02976 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 943223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMDEC(Carbamidomethyl)EAGDNTGLLLR MGYG000003683_00887;MGYG000002397_00495;MGYG000003452_00658;MGYG000002395_00576;MGYG000000756_01285 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00887 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 431682 0 0 280726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 713862 507046 481683 1153516 450371 0 0 0 472226 0 1881129 0 0 632458 0 1795324 0 0 0 550147 344835 1806115 0 0 0 1333977 0 0 966512 0 572301 0 0 0 0 756332 0 0 288914 0 0 0 0 0 0 0 0 0 0 0 0 329194 0 0 0 0 0 393486 0 0 0 0 0 0 0 0 0 0 535778 0 0 0 0 0 0 0 0 0 0 384848 0 0 0 0 284455 0 0 0 0 359492 0 0 0 0 0 641871 0 783018 0 0 0 0 0 0 187302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMDKLDEK MGYG000002834_01606;MGYG000003697_01975;MGYG000001770_00647 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,2FNG9@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 1.0 P 0.6666666666666666 COG0226 ABC-type phosphate transport system, periplasmic component 0.6666666666666666 - 1.0 - 1.0 - 1.0 ko:K02040 0.6666666666666666 ko02010,ko02020,ko05152,map02010,map02020,map05152 0.6666666666666666 M00222 0.6666666666666666 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 0.6666666666666666 3.A.1.7 0.6666666666666666 - 1.0 - 1.0 PBP_like_2 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002834_01606 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Two-component system|Tuberculosis 0.6666666666666666 K02040:pstS; phosphate transport system substrate-binding protein 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1663509 0 0 0 0 2641734 0 0 0 0 2508706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMEENKAQIAK MGYG000001345_03160;MGYG000001337_01162;MGYG000000013_02001;MGYG000002549_04073;MGYG000001378_04005;MGYG000000236_03679;MGYG000000196_04881;MGYG000000029_03397;MGYG000002281_03183 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4372@1|root,COG4372@2|Bacteria,4NJGZ@976|Bacteroidetes,2G2H0@200643|Bacteroidia,4AKNU@815|Bacteroidaceae 0.7777777777777778 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_03160 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 588112 0 682367 0 734715 0 0 0 0 933078 0 0 0 0 0 0 0 0 0 0 545449 0 675335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448605 0 853256 0 231985 0 0 0 0 1430397 0 0 0 0 0 0 0 0 0 0 611367 0 597766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 412943 0 370424 0 0 0 0 596512 0 0 0 0 0 0 0 0 0 0 304740 0 468385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 558106 0 470522 0 479062 0 0 0 0 943514 0 0 0 0 0 0 0 0 0 0 0 0 222751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 129259 0 485619 0 813267 0 0 0 0 764979 0 0 0 0 0 0 0 0 0 0 780147 0 537919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMEENKEQIAK MGYG000001313_01931;MGYG000004185_01081;MGYG000001346_03599;MGYG000003681_00353 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4372@1|root,COG4372@2|Bacteria,4NJGZ@976|Bacteroidetes,2G2H0@200643|Bacteroidia,4AKNU@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_01931 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 265566 0 0 0 0 0 0 0 150367 0 453080 448629 0 293846 0 0 0 0 0 0 182155 174111 0 330013 0 228315 0 0 0 322684 134054 0 0 0 0 0 0 0 864663 0 1061772 0 820271 781917 0 0 679999 756722 812642 1629164 0 801696 0 0 0 209073 0 0 673250 757325 386483 483749 0 749406 0 502272 802428 830911 523937 0 778048 0 0 545302 794464 771812 803936 0 1158309 0 1162755 1061535 0 0 1191896 895429 1215967 1081100 0 924448 0 0 0 1243702 0 0 971217 771759 1037843 842701 0 1025435 0 1279423 832557 1075672 1088085 0 782396 0 0 1086398 1141252 850076 628742 0 1030085 0 1061778 721764 0 0 622400 842214 1090040 1192094 0 763496 0 0 0 517402 0 0 636461 880696 0 505489 0 1131341 0 634647 916457 997851 727286 0 1119558 0 0 954203 681883 1010281 0 0 0 0 245919 0 0 0 0 0 785711 0 0 0 0 0 0 422835 0 0 0 207013 0 0 0 0 0 419851 0 461540 0 0 290969 0 0 0 0 0 +(Gln->pyro-Glu)QMEVLEAIK MGYG000004785_01065;MGYG000000142_02501;MGYG000000200_00066;MGYG000002312_01594;MGYG000000002_02252;MGYG000003409_00273;MGYG000000216_02769;MGYG000003821_01555;MGYG000001338_02424;MGYG000002966_01692;MGYG000000184_00686;MGYG000000201_00500;MGYG000000263_02678;MGYG000001602_02146;MGYG000000806_02369;MGYG000000050_00432;MGYG000000743_01335;MGYG000000213_00152 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3XZQ5@572511|Blautia 0.7777777777777778 186801|Clostridia 1.0 E 0.8888888888888888 Psort location Cytoplasmic, score 8.87 0.7777777777777778 acsE 0.8888888888888888 - 1.0 2.1.1.258 0.8888888888888888 ko:K15023 0.8888888888888888 ko00720,ko01120,ko01200,map00720,map01120,map01200 0.8888888888888888 M00377 0.8888888888888888 R02289,R10243 0.8888888888888888 RC00004,RC00113,RC01144,RC02871,RC02977 0.8888888888888888 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pterin_bind 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004785_01065 0.05555555555555555 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the N(5) group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein.-!-Involved, together with EC 1.2.7.4 and EC 2.3.1.169, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea. (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein] = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+). 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 0.8888888888888888 K15023:acsE; 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258] 0.8888888888888888 none 1.0 0 0 0 0 0 0 0 0 0 0 670597 0 0 0 0 0 0 0 264205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 118129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMFDAVC(Carbamidomethyl)AAC(Carbamidomethyl)GK MGYG000000039_01677;MGYG000002223_00262;MGYG000003291_01619;MGYG000000589_01601;MGYG000002272_00439;MGYG000002545_01146;MGYG000003899_00602;MGYG000003166_00747;MGYG000002641_01194;MGYG000002274_00854;MGYG000001255_02057;MGYG000001300_02903;MGYG000002651_01055;MGYG000002224_01668 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Probable zinc-ribbon domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-trcl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000039_01677 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 417731 465406 975284 878158 0 499905 533123 239782 601147 528999 385711 0 348482 844089 425862 435709 466813 584002 1122322 562645 0 555180 607450 738345 631147 785189 550669 1308948 0 160776 573103 234393 742754 835080 235094 442355 430037 698540 1332016 1127261 1436418 1948999 881892 1420987 2329737 854554 1561156 438743 870540 1169843 1016515 2292253 1957971 1255393 2227090 829208 2880371 2016773 883697 957066 1035878 867524 2114531 1825981 1934363 921801 0 973311 1155961 934383 1551642 1487218 502720 1202322 1453878 1059230 0 0 0 0 0 0 0 0 271508 0 0 0 331517 402897 0 0 0 1123308 0 0 148583 0 1045460 0 0 324141 0 1209209 0 0 0 0 0 177072 0 0 0 165730 505486 249778 385196 633479 489916 861288 1054287 341484 682802 539008 0 663560 601335 726624 714675 310052 290448 400846 860412 149648 633395 0 306376 0 599664 743122 636787 0 0 1049282 302206 286894 435974 1542313 0 778407 759493 437267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721643 0 0 0 0 821551 0 0 0 0 640401 0 0 0 0 0 0 0 133897 0 0 +(Gln->pyro-Glu)QMFDAVC(Carbamidomethyl)ASC(Carbamidomethyl)GK MGYG000003937_01603;MGYG000004732_00815 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Probable zinc-ribbon domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-trcl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01603 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 205547 0 0 0 0 0 264446 0 0 0 0 494472 0 0 0 0 404066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746220 0 0 0 0 0 693589 0 0 0 0 631978 0 0 0 0 617928 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMFEAEGYEVVAINDLTSPK MGYG000004732_01055;MGYG000000215_01375;MGYG000003937_01177 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 0.6666666666666666 C 0.6666666666666666 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004732_01055 0.3333333333333333 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28333051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMFGAEGFEIVAINDLTSPK MGYG000000301_01012;MGYG000000212_01474;MGYG000000171_00850;MGYG000000002_02120;MGYG000002212_00259;MGYG000002966_00075;MGYG000001338_02547;MGYG000000133_02283;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000001315_01699;MGYG000003702_00925;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_01012 0.0625 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 981187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2870960 369720 0 0 0 0 0 0 1546145 0 0 0 215011 0 0 5012945 0 0 0 0 0 0 0 0 0 777936 0 0 0 0 0 0 0 0 0 0 0 0 0 2462223 0 0 0 0 5541808 0 0 0 0 1887770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5409323 848241 0 0 0 2435335 0 440610 4276303 975509 0 0 0 0 0 0 0 0 0 0 208187 0 0 0 0 0 0 0 0 0 0 369423 402129 0 0 0 0 3947230 3812625 3448907 0 0 213575 0 3142294 7600482 8673774 6602692 0 0 0 0 0 0 0 0 3615840 0 13897593 0 0 0 0 0 0 0 0 0 0 7006703 3946444 0 0 0 0 7585240 10464993 16064280 0 0 9285366 0 5722737 +(Gln->pyro-Glu)QMFGAEGYEVVAINDLTSPK MGYG000000280_02459;MGYG000000038_02185;MGYG000003582_01256;MGYG000001607_01815;MGYG000000204_00778;MGYG000001310_02090;MGYG000004740_01468;MGYG000001319_00348;MGYG000000187_02264;MGYG000000262_01195;MGYG000002517_01026;MGYG000001299_00204;MGYG000000251_00555;MGYG000002528_00367;MGYG000003450_00202;MGYG000002279_00557;MGYG000000398_00286;MGYG000002025_02240;MGYG000000164_00800;MGYG000000271_03250;MGYG000004271_00554;MGYG000000562_01218;MGYG000001421_02311;MGYG000004317_00142;MGYG000000404_00344;MGYG000004735_01946;MGYG000000153_00303;MGYG000002492_01379;MGYG000001652_01009;MGYG000000489_00503;MGYG000004593_01977 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.41935483870967744 186801|Clostridia 0.9354838709677419 G 0.6129032258064516 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5161290322580645 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_02459 0.03225806451612903 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 480344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450303 0 0 0 0 0 0 0 0 0 0 0 0 330860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 589897 0 0 0 0 0 0 0 0 0 0 315521 0 4144471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5728994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15241371 0 +(Gln->pyro-Glu)QMHDLKPAPGAK MGYG000001292_02343;MGYG000002469_01750;MGYG000003683_01119 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,4D0R9@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 binds to the 23S rRNA 1.0 rplO 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001292_02343 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1420415 0 0 0 0 542349 0 0 0 0 1179874 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 145331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMKDAIIK MGYG000000243_02364;MGYG000000042_02977;MGYG000001787_00060 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,4AKHK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000243_02364 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMMNDFASR MGYG000000133_00637 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3XYJC@572511|Blautia 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00637 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468208 0 0 0 0 0 0 0 0 0 0 739950 0 0 0 0 0 0 498427 0 0 0 0 0 0 0 0 0 0 0 834202 0 0 0 0 389290 +(Gln->pyro-Glu)QMNVQFISHDKINQLR MGYG000000255_01546 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,21Z64@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 EK 1.0 COG COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Aminotran_MocR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01546 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 514132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMNYSEYESDQFKK MGYG000002438_03723 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1155@1|root,COG1155@2|Bacteria,4NIB6@976|Bacteroidetes,2FMQ6@200643|Bacteroidia,22WQG@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit 1.0 atpA 1.0 - 1.0 3.6.3.14,3.6.3.15 1.0 ko:K02117 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03723 1.0 H(+)-transporting two-sector ATPase. | Na(+)-transporting two-sector ATPase. mitochondrial ATPase. | sodium-transporting two-sector ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. | A multisubunit ATPase transporter found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis.-!-The enzyme is similar to EC 7.1.2.2 but pumps Na(+) rather than H(+). cf. EC 7.2.2.3 and EC 7.2.2.4.-!-Formerly EC 3.6.3.15. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. | ATP + H2O + 4 Na(+)(in) = ADP + H(+) + 4 Na(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways 1.0 K02117:ATPVA, ntpA, atpA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 529676 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMQFFAAR MGYG000003683_00301;MGYG000000756_01431;MGYG000002469_00869;MGYG000001292_01825 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 Pyruvate formate lyase-like 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bac_luciferase,Fer4_12,Gly_radical,PFL-like,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00301 0.25 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146125 0 0 0 0 0 0 0 0 0 0 0 436592 0 0 0 64725 98292 306273 0 0 0 356916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMQFFGAR MGYG000003872_00149;MGYG000002534_00608;MGYG000002534_01733;MGYG000000235_02550;MGYG000002354_02556;MGYG000002507_03821;MGYG000002506_00229;MGYG000001712_00487;MGYG000002438_01173;MGYG000002057_00708;MGYG000003420_01555;MGYG000000421_00811;MGYG000001913_00352;MGYG000002415_02033;MGYG000000323_00781;MGYG000000093_01913;MGYG000001464_02452;MGYG000002159_01115;MGYG000002963_00984;MGYG000004453_00589;MGYG000004632_01941;MGYG000002504_03659;MGYG000000215_01434;MGYG000002494_01739;MGYG000002515_00999;MGYG000000034_01553;MGYG000001326_00363;MGYG000002477_04855;MGYG000000919_01916;MGYG000004743_00132;MGYG000002654_00807;MGYG000001395_02012;MGYG000001325_00972;MGYG000003301_00377;MGYG000002727_01362;MGYG000002494_01412;MGYG000001763_01402;MGYG000003410_00860;MGYG000003470_01473;MGYG000002965_00898;MGYG000001749_02186;MGYG000002535_00167;MGYG000002912_00356;MGYG000001692_01065;MGYG000002535_02788;MGYG000003549_00903;MGYG000002506_02759;MGYG000001405_03199;MGYG000000989_01728 domain d__Bacteria 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36F8M@31979|Clostridiaceae 0.14285714285714285 186801|Clostridia 0.3673469387755102 C 0.9591836734693877 formate acetyltransferase 0.32653061224489793 pflB 0.8367346938775511 - 0.5918367346938775 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 0.673469387755102 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003872_00149 0.02040816326530612 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 209988 221552 259144 44470 240014 233849 224918 387213 256771 88550 0 0 63418 102852 286439 0 161241 0 153803 185147 0 404657 0 336368 371771 234449 202297 0 80297 276273 63477 0 216171 74443 451188 207286 75838 165393 561193 1200005 900566 636728 1558285 2585259 922821 575541 564302 1195774 0 0 780373 919539 753184 1324377 1536068 0 1014770 655651 0 3280931 0 2173035 1248518 671999 531414 0 1560801 1144521 474361 0 986016 486589 599956 512277 580486 1015382 331341 323186 367921 152766 86131 652048 433101 501407 97439 664588 0 0 345618 371360 390739 361355 406271 0 328384 333177 0 488840 0 581121 423985 442190 427076 0 407470 347493 392278 0 388330 449984 340109 85814 356261 128730 83972 84220 61653 167254 60926 155007 0 122559 62533 172208 0 0 93533 0 69352 70714 74750 0 76183 101911 0 105201 0 0 0 83077 101790 0 0 142005 65211 0 77286 79089 153230 107278 57607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMQVGGKDPLVPEENDKTTVIALR MGYG000002504_04484;MGYG000002477_00514;MGYG000002534_00089;MGYG000002323_04146;MGYG000002494_02311;MGYG000003372_02790;MGYG000002506_03300;MGYG000000235_03676;MGYG000002515_03814 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1758@1|root,COG1758@2|Bacteria,1N6TX@1224|Proteobacteria,1SCSR@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 K 1.0 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits 1.0 rpoZ 1.0 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03060 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002504_04484 0.1111111111111111 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03060:rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1109683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268297 0 806019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMSLTLHRPPGR MGYG000002961_00589;MGYG000003266_01369;MGYG000002947_00479;MGYG000004681_01011;MGYG000002775_01356 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CU9G@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 - 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000002961_00589 0.2 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMTEVTDIDGHK MGYG000002293_02198;MGYG000002834_01646;MGYG000003697_02473 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FM0N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 8-amino-7-oxononanoate synthase 1.0 bioF 1.0 - 1.0 2.3.1.29,2.3.1.47 1.0 ko:K00639,ko:K00652 1.0 ko00260,ko00780,ko01100,map00260,map00780,map01100 1.0 M00123,M00573,M00577 1.0 R00371,R03210,R10124 1.0 RC00004,RC00039,RC00394,RC02725 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_02198 0.3333333333333333 glycine C-acetyltransferase. | 8-amino-7-oxononanoate synthase. 2-amino-3-ketobutyrate coenzyme A ligase. | AONS. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. | The enzyme catalyzes the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis.-!-Pimeloyl-CoA can be used with lower efficiency. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. | 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Biotin metabolism|Metabolic pathways 1.0 K00639:kbl, GCAT; glycine C-acetyltransferase [EC:2.3.1.29]|K00652:bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 748134 0 966047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMTFEQSLR MGYG000000133_00307;MGYG000000301_00956 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3XZ1G@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP_cyclohyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00307 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 849131 0 0 0 0 0 +(Gln->pyro-Glu)QMTGKEPSK MGYG000004740_00081;MGYG000002492_01740;MGYG000003694_01621 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004740_00081 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 512934 0 0 959314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 800827 0 0 0 0 532123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMTGSDFSEITK MGYG000003215_00872;MGYG000000164_02761;MGYG000000249_01548;MGYG000000146_01048;MGYG000002279_01069;MGYG000000038_01579 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3XZ12@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003215_00872 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2351558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QMVAHALTK MGYG000002528_00945;MGYG000000233_00055 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,26AUV@186813|unclassified Clostridiales 0.5 186801|Clostridia 1.0 I 0.5 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00945 0.5 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 698262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1751736 0 0 0 0 1065265 0 0 0 0 1699482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466468 0 0 0 0 1040674 0 0 0 0 1617139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QN(Deamidated)ASVFSTQR MGYG000002517_00608 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00608 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 163296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1307629 0 0 0 0 0 0 1936425 1843475 805186 0 0 0 1510804 1973199 0 0 0 0 0 0 0 0 0 0 1777842 1993978 0 0 1371255 0 0 0 0 0 0 1765578 0 0 0 0 0 0 0 0 0 0 274493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246247 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QN(Deamidated)GEHGVWQYK MGYG000000489_02253;MGYG000000076_02271;MGYG000000187_02311;MGYG000002492_02848;MGYG000000271_00907;MGYG000002517_02750;MGYG000001637_01313 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 L 1.0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site 1.0 mfd 1.0 - 1.0 - 1.0 ko:K03723 1.0 ko03420,map03420 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03400 1.0 - 1.0 - 1.0 - 1.0 CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF,UB2H 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000489_02253 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Nucleotide excision repair 1.0 K03723:mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789274 0 0 0 0 489909 0 0 0 0 725267 0 0 0 0 0 0 0 269484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 765795 0 0 0 0 794560 0 0 0 0 939012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243452 0 0 0 0 0 0 0 0 0 0 485210 0 0 0 0 0 0 0 515609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297087 461925 0 0 0 0 0 0 0 0 0 523284 0 0 0 0 0 0 0 544808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8282668 249684 0 0 0 0 493353 0 0 0 0 552800 0 0 0 0 0 0 0 8004985 0 0 +(Gln->pyro-Glu)QN(Deamidated)PSFGHPEK MGYG000000213_01298 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp003477525|m__MGYG000000213 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia,3WGYT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 MCRA family 1.0 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000213_01298 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 - 1.0 K10254:ohyA, sph; oleate hydratase [EC:4.2.1.53] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 462515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNAHNMVVQTNK MGYG000002478_01460 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG3534@1|root,COG3534@2|Bacteria,4NGKW@976|Bacteroidetes,2FM0F@200643|Bacteroidia,4AMJ6@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Carbohydrate binding domain protein 1.0 - 1.0 - 1.0 3.2.1.55 1.0 ko:K01209 1.0 ko00520,map00520 1.0 - 1.0 R01762 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH51 1.0 - 1.0 Alpha-L-AF_C,CBM_4_9 1.0 3.2.1.55 1.0 GH51 1.0 GH51 1.0 GH51 1.0 MGYG000002478_01460 1.0 non-reducing end alpha-L-arabinofuranosidase. arabinosidase. Acts on alpha-L-arabinofuranosides, alpha-L-arabinans containing (1,3)- and/or (1,5)-linkages, arabinoxylans and arabinogalactans.-!-Some EC 3.2.1.23 and EC 3.2.1.38 enzymes also hydrolyze alpha-L- arabinosides. cf. EC 3.2.1.185.-!-Formerly EC 3.2.1.79. Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 K01209:abfA; alpha-L-arabinofuranosidase [EC:3.2.1.55] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604539 0 0 0 0 763945 0 0 0 0 414467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258065 0 0 0 0 387325 0 0 0 0 453454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1499895 0 0 0 0 967216 0 0 0 0 956623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3618718 0 0 0 0 3253417 0 0 0 0 2612501 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNAIIFSTER MGYG000004276_00442;MGYG000002926_01410 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004276_00442 0.5 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 121304 0 0 0 0 0 225089 202001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270018 268451 0 0 0 0 0 0 0 168936 0 0 0 0 587751 969725 0 919918 0 0 0 827621 0 0 0 0 519600 757487 701517 502627 584961 0 0 0 0 0 0 0 825471 1195697 0 0 0 0 0 0 0 701394 0 0 630808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334035 0 370273 0 0 0 522515 0 0 0 0 0 762511 0 0 0 0 0 0 0 0 0 0 0 138716 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNC(Carbamidomethyl)IILSSQR MGYG000004475_00656 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900556015|m__MGYG000004475 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004475_00656 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 836642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNDIIYVTPNK MGYG000002478_00603;MGYG000002478_02532 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1596@1|root,COG1596@2|Bacteria,4NNJT@976|Bacteroidetes,2FNYD@200643|Bacteroidia,4AKVB@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 COG1596 Periplasmic protein involved in polysaccharide export 1.0 - 1.0 - 1.0 - 1.0 ko:K01991 1.0 ko02026,map02026 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02000 1.0 1.B.18 1.0 - 1.0 - 1.0 Poly_export,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00603 0.5 - - - - 1.0 1.0 1.0 1.0 Biofilm formation - Escherichia coli 1.0 K01991:wza, gfcE; polysaccharide biosynthesis/export protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 839616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564542 0 0 0 0 267145 0 0 0 0 456219 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNDILAIVK MGYG000000200_01193;MGYG000000184_01884;MGYG000002312_00710;MGYG000004785_01922;MGYG000001338_00217 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3Y05R@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000200_01193 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04078:groES, HSPE1; chaperonin GroES 1.0 none 1.0 0 344375 103319 0 167612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99110 574786 0 0 0 0 0 0 0 693935 0 0 160907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596071 336705 57765 0 0 0 0 0 0 355202 0 0 74836 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230975 427954 74038 0 0 0 0 0 0 351119 109077 0 153534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530534 220926 157612 0 0 0 0 164314 0 534047 330280 0 100907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456460 695112 435705 0 0 0 0 231297 +(Gln->pyro-Glu)QNDVLAIVK MGYG000000164_00893 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3Y05R@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_00893 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04078:groES, HSPE1; chaperonin GroES 1.0 none 1.0 429245 0 0 0 0 0 763429 0 469628 0 0 0 307128 396333 301986 0 0 0 0 0 730844 0 0 0 454876 450740 416299 0 388953 0 0 0 0 0 0 590290 441422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78988 0 0 0 0 0 0 0 0 0 0 0 97246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1390382 0 0 0 0 0 0 208135 0 0 0 0 151078 0 0 121786 0 0 0 0 0 0 424732 0 0 0 0 0 0 0 0 122116 0 109280 0 0 0 0 136140 0 0 0 0 0 0 0 0 0 0 98971 0 117758 0 170734 0 0 0 0 0 0 129987 198369 0 +(Gln->pyro-Glu)QNGDWEYANFADDNENGYTVK MGYG000002492_00221 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,25VT8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00221 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1522467 0 0 0 0 1048899 0 0 0 0 1561828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNGEHGVWQYK MGYG000000489_02253;MGYG000000076_02271;MGYG000000187_02311;MGYG000002492_02848;MGYG000000271_00907;MGYG000002517_02750;MGYG000001637_01313 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 L 1.0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site 1.0 mfd 1.0 - 1.0 - 1.0 ko:K03723 1.0 ko03420,map03420 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03400 1.0 - 1.0 - 1.0 - 1.0 CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF,UB2H 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000489_02253 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Nucleotide excision repair 1.0 K03723:mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] 1.0 none 1.0 708598 463909 0 712609 0 430523 221376 252790 550088 732668 795802 520449 0 596886 370829 801906 682827 1051510 585290 752261 607100 462983 1306917 363890 620339 625786 418308 1298617 0 398431 0 0 0 600837 0 683541 645713 0 0 141364 467536 243141 0 0 0 0 218375 0 205882 0 0 0 0 448526 0 1729127 0 0 0 0 1716777 0 0 0 0 4009863 0 0 0 0 578924 0 0 187623 0 715043 839108 1181902 1327108 696253 0 457501 495505 871657 859193 818683 472685 461060 0 865083 1119408 1050931 717218 611536 559600 712501 505250 564769 867378 465384 1120602 546833 1076228 1535669 0 749371 0 0 1403570 777575 0 691012 1069721 1168199 1543172 159623 437503 1633164 0 610428 1265244 1888230 2045268 988293 1062115 904643 0 1734793 1924508 941830 1892038 874784 1323676 1668980 1919337 0 0 647643 2189814 1587577 1541140 399134 0 1414388 0 0 531639 860051 0 1400230 1569924 619617 1834494 1593897 1894131 0 0 1488338 1515054 1474879 1452101 2331564 1381206 1530530 0 1871205 2519680 1643992 1849728 955377 1833461 1319920 552963 1610150 1721409 2122309 2160018 1566261 2003872 1409864 0 1030610 0 0 2010935 1922729 0 1825548 1945778 1825449 +(Gln->pyro-Glu)QNHEPYSMDAAMAK MGYG000001500_03163;MGYG000004196_00482;MGYG000004475_01030;MGYG000004487_00391;MGYG000002794_01608;MGYG000002720_01506;MGYG000002926_00639;MGYG000002143_01787 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2N683@216572|Oscillospiraceae 0.875 186801|Clostridia 0.875 I 1.0 Psort location Cytoplasmic, score 9.97 0.875 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 0.875 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001500_03163 0.125 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 783194 686116 441282 0 665976 864963 993312 1282772 1035770 0 0 0 0 877441 1182114 0 0 0 691429 0 0 531562 0 962243 783106 1035024 957522 0 869071 0 0 676194 463752 978560 0 1241831 906970 604214 0 0 0 0 0 0 0 125723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 137748 0 0 0 0 0 0 0 0 0 239441 0 314899 0 297585 0 0 0 376706 386865 364042 0 0 0 0 411806 455326 0 0 0 689042 0 0 382240 0 0 473956 360082 334415 0 333332 0 0 0 343584 295415 0 282363 290590 342685 0 466690 353590 0 0 190907 304688 0 0 0 0 0 0 403986 398937 0 0 0 220791 0 0 0 0 0 359956 439277 503255 0 522351 0 0 358684 377558 0 0 0 0 305133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNIEAVTNDAFMR MGYG000001300_00301;MGYG000002223_00312 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Radical SAM domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,Radical_SAM,SPASM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00301 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203927 0 581659 0 0 0 0 0 1068131 0 0 0 0 0 0 755294 0 0 817183 0 1246723 0 0 0 0 0 1025098 880640 882822 0 0 0 0 0 0 0 0 537490 516913 0 0 0 0 0 0 0 190546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 186644 0 0 0 0 0 290882 0 0 0 0 0 0 243500 0 0 232242 0 150599 0 0 0 0 0 291496 189969 0 0 0 0 0 0 0 0 0 234136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNLAQQER MGYG000000107_04662;MGYG000000107_02891;MGYG000002494_04260;MGYG000002506_02537;MGYG000002323_03405 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0021@1|root,COG0021@2|Bacteria,1MUEY@1224|Proteobacteria,1RMWP@1236|Gammaproteobacteria,3XMMK@561|Escherichia 0.8 1236|Gammaproteobacteria 1.0 G 0.8 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate 1.0 tktA 1.0 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECABU_c1320.ECABU_c27750,iLF82_1304.LF82_2271,iNRG857_1313.NRG857_12300,iSDY_1059.SDY_3141,iYL1228.KPN_01127,ic_1306.c2990 0.8 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000107_04662 0.2 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNLATFC(Carbamidomethyl)QTWDDENVHK MGYG000002515_02735;MGYG000002506_00791;MGYG000002323_02099;MGYG000002506_03156;MGYG000002515_01515;MGYG000002323_00193 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,1RNSQ@1236|Gammaproteobacteria,3XMMA@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria 1.0 gadB 0.6666666666666666 GO:0003674,GO:0003824,GO:0004351,GO:0006873,GO:0006885,GO:0008150,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019725,GO:0030003,GO:0030004,GO:0030641,GO:0042592,GO:0045852,GO:0048878,GO:0050801,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 1.0 4.1.1.15 1.0 ko:K01580 1.0 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 1.0 M00027 1.0 R00261,R00489,R01682,R02466 1.0 RC00299 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECUMN_1333.ECUMN_1747,iUTI89_1310.UTI89_C1707,ic_1306.c1922 0.6666666666666666 Pyridoxal_deC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_02735 0.16666666666666666 glutamate decarboxylase. L-glutamate 1-carboxy-lyase. The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate. H(+) + L-glutamate = 4-aminobutanoate + CO2. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|beta-Alanine metabolism|Taurine and hypotaurine metabolism|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Quorum sensing|GABAergic synapse|Type I diabetes mellitus 1.0 K01580:E4.1.1.15, gadB, gadA, GAD; glutamate decarboxylase [EC:4.1.1.15] 1.0 none 1.0 0 576599 765679 0 667959 1782871 715771 1359484 587465 984220 0 0 596950 737744 0 546125 0 0 773311 526990 0 1314212 0 1267770 498141 0 773463 0 0 811133 0 0 628378 680481 820740 0 0 866198 0 0 0 0 0 799593 0 0 0 0 0 0 260011 0 0 0 0 0 0 0 0 665647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 626361 0 465710 0 507577 0 0 851261 0 0 693703 0 0 0 0 0 434259 0 486677 0 0 0 0 0 0 0 0 376382 0 580066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187039 0 0 0 0 0 0 0 0 0 0 193553 349529 0 0 0 0 0 0 0 0 0 193157 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNLTSPDGNLK MGYG000001306_00997 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,2FKZT@200643|Bacteroidia,4AMS4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG NOG06228 non supervised orthologous group 1.0 susB 1.0 GO:0000272,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0004558,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:0090599,GO:1901575 1.0 3.2.1.20,3.2.1.3 1.0 ko:K01187,ko:K21574 1.0 ko00052,ko00500,ko01100,map00052,map00500,map01100 1.0 - 1.0 R00028,R00801,R00802,R01790,R01791,R06087,R06088 1.0 RC00028,RC00049,RC00077 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH31,GH97 1.0 - 1.0 GH97_C,GH97_N,Glyco_hydro_97 1.0 3.2.1.3|3.2.1.20 1.0 GH97 1.0 GH97 1.0 GH97 1.0 MGYG000001306_00997 1.0 alpha-glucosidase. | glucan 1,4-alpha-glucosidase. maltase-glucoamylase. | lysosomal alpha-glucosidase. Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.-!-The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links. | Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides.-!-This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides.-!-EC 3.2.1.20 from mammalian intestine can catalyze similar reactions. Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. | Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose. 1.0 1.0 1.0 1.0 Galactose metabolism|Starch and sucrose metabolism|Metabolic pathways 1.0 K01187:malZ; alpha-glucosidase [EC:3.2.1.20]|K21574:susB; glucan 1,4-alpha-glucosidase [EC:3.2.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1542124 0 0 0 0 2223545 0 0 0 0 2879238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1551826 0 0 0 0 2607433 0 0 0 0 2857958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559552 0 0 0 0 0 0 0 0 0 414657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1987332 0 0 0 0 4416195 0 0 0 0 8766094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1286722 0 0 0 0 983283 0 0 0 0 957516 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNNDFTVELEENHR MGYG000000074_00310 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 2FK1S@1|root,34BPZ@2|Bacteria,4P558@976|Bacteroidetes,2FYSJ@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Bacterial protein of unknown function (YtfJ_HI0045) 1.0 - 1.0 - 1.0 - 1.0 ko:K07109 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 YtfJ_HI0045 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00310 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07109:K07109; uncharacterized protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736487 710440 0 0 0 0 0 0 0 0 0 990586 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNPADVEALMAC(Carbamidomethyl)K MGYG000001300_00245;MGYG000002272_01434;MGYG000000022_01262;MGYG000003291_01082;MGYG000003166_00302;MGYG000002040_00320 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00245 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298141 0 0 470776 0 0 0 0 0 0 0 0 0 540154 0 0 0 0 494315 422814 0 0 0 0 630933 460707 333798 0 0 0 383314 0 0 0 0 0 339545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254006 0 0 0 0 0 0 0 0 0 0 341439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNPEKAAR MGYG000002298_00647;MGYG000000164_01756;MGYG000001338_02036;MGYG000000142_01058;MGYG000000200_00183;MGYG000000002_01844;MGYG000000212_02086;MGYG000000031_03215;MGYG000000171_02087 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3XZ4K@572511|Blautia 0.5555555555555556 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002298_00647 0.1111111111111111 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNPEKAER MGYG000000133_02129 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000133_02129 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 210520 0 0 0 0 0 0 0 0 0 364551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732156 0 924397 1329999 0 0 1157827 0 633521 1224447 1810675 0 1171747 1894212 0 643827 0 0 628330 0 1037671 0 0 0 1029195 1040770 1364234 0 1471251 0 1206864 0 2092867 0 0 1628658 949262 803974 +(Gln->pyro-Glu)QNPITSIKDQNR MGYG000003697_00848;MGYG000002293_01475;MGYG000002960_00382;MGYG000002834_00840 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG3579@1|root,COG3579@2|Bacteria,4NE02@976|Bacteroidetes,2FN7G@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase C1-like family 1.0 pepC 1.0 - 1.0 3.4.22.40 1.0 ko:K01372 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Peptidase_C1,Peptidase_C1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_00848 0.25 bleomycin hydrolase. aminopeptidase C (Lactococcus lactis). The active sites are on the walls of a central channel through the molecule, and access of substrate molecules to them is obstructed by this and by the C-terminus of each polypeptide chain.-!-Bleomycin can scarcely be the natural substrate, and there are reports of limited endopeptidase activity.-!-Known from bacteria as well as eukaryotic organisms.-!-Hydrolase H from chicken muscle has many similarities to bleomycin hydrolase, but hydrolyzes Ph-CO-Arg-2-naphthylamine as well as aminopeptidase substrates.-!-Belongs to peptidase family C1. Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred. 1.0 1.0 1.0 1.0 - 1.0 K01372:BLMH, pepC; bleomycin hydrolase [EC:3.4.22.40] 1.0 none 1.0 0 0 0 0 484962 606930 0 0 0 0 0 0 644705 0 0 0 0 1075545 0 0 0 596465 420421 0 0 0 0 748246 0 0 0 0 339549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196510 0 0 0 0 0 0 0 0 0 396064 0 0 0 0 1539243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1955160 0 1120796 1266886 0 0 0 0 0 0 985549 0 0 0 0 2005026 0 0 0 1271471 2514971 896540 0 0 0 2014516 0 0 0 0 1399432 0 0 0 0 1378941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNTQQNSNVEKIEK MGYG000003693_02982 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia,4AMCZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_02982 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682810 0 0 0 0 1496606 0 0 0 0 1006161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 556643 0 0 0 0 632447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNVFTDPQKPMK MGYG000001338_02425;MGYG000000301_00509;MGYG000000142_02502;MGYG000000200_00067;MGYG000000133_01786;MGYG000004735_00332;MGYG000000216_02768 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 0.8571428571428571 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02425 0.14285714285714285 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00197:cdhE, acsC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] 1.0 none 1.0 0 423541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 892943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 434635 0 0 0 0 0 0 0 0 0 0 1045897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1030421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1335831 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNVVLATIEALK MGYG000002492_00392 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00392 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNVVLATLNALSQLK MGYG000002517_02856 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02856 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1106813 0 714529 0 0 0 0 765714 679234 1102585 0 0 0 0 0 745455 0 0 0 0 0 0 0 0 0 1307557 0 0 0 1060440 0 0 0 1312493 0 0 579567 0 +(Gln->pyro-Glu)QNVYTDPQKPMK MGYG000000171_00588;MGYG000000184_00685;MGYG000002298_01760 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_00588 0.3333333333333333 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00197:cdhE, acsC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] 1.0 none 1.0 0 589423 0 0 0 799787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 584440 0 0 0 0 0 0 0 0 328703 0 0 0 0 0 0 0 0 996266 0 0 0 155230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 668653 0 170142 0 0 0 0 0 0 1147299 0 0 0 0 0 0 0 0 646859 0 0 0 232771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 570058 0 451987 0 0 0 0 0 0 210961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270665 0 0 0 0 0 0 247044 0 0 0 0 0 0 0 0 0 0 0 0 536572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QNYIIVNSEK MGYG000000074_01846 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG2825@1|root,COG2825@2|Bacteria,4NH46@976|Bacteroidetes,2FQDW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01846 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1120708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QPDAMTHPDGMQIK MGYG000002476_04117;MGYG000003372_03956;MGYG000002535_04634;MGYG000002515_03227;MGYG000002494_02024;MGYG000002323_00362;MGYG000001692_02603;MGYG000002502_00525;MGYG000002534_00367;MGYG000002500_04458;MGYG000002477_00211;MGYG000002504_03997 order d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales 1.0 COG0664@1|root,COG0664@2|Bacteria,1MXID@1224|Proteobacteria,1RMIZ@1236|Gammaproteobacteria,3XPHB@561|Escherichia 0.9166666666666666 1236|Gammaproteobacteria 0.9166666666666666 K 1.0 class I promoters have a single CRP-binding site upstream of the RNA polymerase (RNAP)- binding site, whereas in class II promoters the single CRP- and RNAP-binding site overlap, CRP making multiple contacts with RNAP. Class III promoters require multiple activator molecules, including at least one CRP dimer. It can act as an activator, repressor, coactivator or corepressor. Induces a severe bend in DNA (about 87 degrees), bringing upstream promoter elements into contact with RNAP. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP. High levels of active CRP are detrimental to growth. Plays a major role in carbon catabolite repression (CCR). CCR involves cAMP, adenylate cyclase (cyaA), CRP and the EIIA-Glc component of the PTS (crr). In the presence of glucose EIIA-Glc is dephosphorylated, and does not activate adenylate cyclase, leading to reduced cAMP and thus decreased CRP activity. Also plays a role in many other processes (see PubMed 22573269) 0.9166666666666666 crp 1.0 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 0.9166666666666666 - 1.0 ko:K10914 1.0 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03000 1.0 - 1.0 - 1.0 - 1.0 Crp,HTH_Crp_2,cNMP_binding 0.9166666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002476_04117 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 Two-component system|Quorum sensing|Biofilm formation - Pseudomonas aeruginosa|Biofilm formation - Escherichia coli|Biofilm formation - Vibrio cholerae 1.0 K10914:crp; CRP/FNR family transcriptional regulator, cyclic AMP receptor protein 1.0 none 1.0 1430939 454747 1611635 0 1989644 436165 1810448 0 0 1315505 0 0 0 0 0 0 2996984 0 2127953 0 0 1331176 0 2688125 2195868 552486 0 0 2235758 0 0 0 2356865 0 0 0 2727227 713418 2159320 490794 779983 0 637814 1071322 664979 0 0 1825598 0 0 0 0 0 0 1611732 0 877976 0 0 1220595 0 2020862 1907178 1506046 0 0 1840162 0 0 0 830109 0 0 0 2112717 2723328 2387865 1796435 2226434 0 2924042 2804645 2794560 0 0 798626 0 0 0 0 0 0 3330896 0 2236914 0 0 2320404 0 650378 2345817 2657863 0 0 2681130 0 0 0 2624365 0 0 0 2419560 2947425 2104624 2423719 2474280 0 1976343 2212499 414145 0 0 976688 0 0 0 0 0 0 2554252 0 1959195 0 0 2582328 0 3346891 2588281 2324186 0 0 333760 0 0 0 546685 0 0 0 158723 2088318 2467313 2304375 2232602 0 2622501 2069622 955581 0 0 2224673 0 0 0 0 0 0 306528 0 2723973 0 0 826262 0 1621109 1089669 1542516 0 0 2854937 0 0 0 629681 0 0 0 1291387 1994027 +(Gln->pyro-Glu)QPDGSLAGDHYK MGYG000000022_00344 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,248C0@186801|Clostridia,3WH1J@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 glucuronate isomerase 1.0 uxaC 1.0 - 1.0 5.3.1.12 1.0 ko:K01812 1.0 ko00040,ko01100,map00040,map01100 1.0 M00061,M00631 1.0 R01482,R01983 1.0 RC00376 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 LacI,UxaC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00344 1.0 glucuronate isomerase. uronic isomerase. Also converts D-galacturonate to D-tagaturonate. D-glucuronate = D-fructuronate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Metabolic pathways 1.0 K01812:uxaC; glucuronate isomerase [EC:5.3.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1609786 0 0 0 0 1617708 0 0 0 0 1370226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564463 0 0 0 0 955172 0 0 0 0 653867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 972025 0 0 0 0 1482796 0 0 0 0 1465522 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QPDGSRHPFDSFIVAK MGYG000002545_01342;MGYG000002040_01325;MGYG000000187_02007 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia,3WHXZ@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 1.0 IQ 1.0 Psort location Cytoplasmic, score 0.6666666666666666 - 1.0 - 1.0 1.1.1.69 0.6666666666666666 ko:K00046 0.6666666666666666 - 0.6666666666666666 - 1.0 - 0.6666666666666666 - 0.6666666666666666 ko00000,ko01000 0.6666666666666666 - 1.0 - 1.0 - 1.0 adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002545_01342 0.3333333333333333 gluconate 5-dehydrogenase. 5-ketogluconate reductase. - (1) D-gluconate + NADP(+) = 5-dehydro-D-gluconate + H(+) + NADPH. (2) D-gluconate + NAD(+) = 5-dehydro-D-gluconate + H(+) + NADH. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 - 0.6666666666666666 K00046:idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1218940 0 0 0 0 1124589 0 0 0 0 1442368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80876 0 0 0 0 288371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618924 0 0 0 0 600923 0 0 0 0 481647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QPEASGDLR MGYG000003681_00522;MGYG000001306_00929;MGYG000003693_01486;MGYG000000781_01663 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia,4ARQC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_00522 0.25 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02110:ATPF0C, atpE; F-type H+-transporting ATPase subunit c 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 589874 0 0 0 0 0 0 0 0 0 135970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490381 0 0 0 0 839477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371464 0 0 0 0 309726 0 0 0 0 483416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1386125 0 0 0 0 0 0 0 0 0 956545 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QPFPGPGLGIR MGYG000001310_00986;MGYG000004847_02038;MGYG000000142_01325;MGYG000000171_01555;MGYG000002528_01386;MGYG000002610_00542;MGYG000004288_01478;MGYG000004735_01261;MGYG000001423_03192;MGYG000000140_02756;MGYG000002223_00095;MGYG000003482_00900;MGYG000000488_00920;MGYG000001602_01517;MGYG000003899_01640;MGYG000003577_01198;MGYG000003828_00369;MGYG000000184_02045;MGYG000002641_00286;MGYG000000915_01126;MGYG000003683_00702;MGYG000000087_02408;MGYG000002274_01246;MGYG000000271_01306;MGYG000000919_02508;MGYG000002835_00594;MGYG000000022_02285;MGYG000001300_00155;MGYG000002298_01935;MGYG000002619_02218;MGYG000002469_00855;MGYG000000187_01380;MGYG000001637_01668;MGYG000002279_02383;MGYG000003628_01363;MGYG000000028_00428;MGYG000000515_01866;MGYG000000242_02030;MGYG000000489_01853;MGYG000001652_00716;MGYG000004296_00217;MGYG000004548_02048;MGYG000001707_02152;MGYG000003422_00594;MGYG000003166_01352;MGYG000000251_01432;MGYG000000200_03164;MGYG000001255_01096;MGYG000001338_03497;MGYG000000216_01091;MGYG000000269_00045;MGYG000000389_01945;MGYG000001374_02320;MGYG000002492_00550;MGYG000002517_02553;MGYG000004733_00652;MGYG000001711_01546;MGYG000000133_02533;MGYG000000213_01020;MGYG000000387_00949;MGYG000001315_00172;MGYG000000194_00055;MGYG000002670_00532;MGYG000001292_01833;MGYG000000204_01415;MGYG000000398_02147;MGYG000001793_01311;MGYG000003486_00521;MGYG000001490_00760;MGYG000001777_00693;MGYG000004797_02013;MGYG000000212_02358 domain d__Bacteria 1.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3WGXK@541000|Ruminococcaceae 0.2777777777777778 186801|Clostridia 0.8888888888888888 F 1.0 Catalyzes the synthesis of GMP from XMP 0.9861111111111112 guaA 1.0 - 0.9305555555555556 6.3.5.2 0.9861111111111112 ko:K01951 0.9861111111111112 ko00230,ko00983,ko01100,map00230,map00983,map01100 1.0 M00050 1.0 R01230,R01231,R08244 1.0 RC00010,RC00204 1.0 ko00000,ko00001,ko00002,ko01000,ko01002 0.9861111111111112 - 1.0 - 1.0 - 0.9861111111111112 ATP_bind_3,GATase,GMP_synt_C,NAD_synthase,ThiI,tRNA_Me_trans 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_00986 0.013888888888888888 GMP synthase (glutamine-hydrolyzing). GMP synthetase (glutamine-hydrolyzing). Involved in the de novo biosynthesis of guanosine nucleotides.-!-An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain.-!-The enzyme can catalyze the second reaction alone in the presence of ammonia.-!-Formerly EC 6.3.4.1. ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate. 0.9861111111111112 0.9861111111111112 0.9861111111111112 0.9861111111111112 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways 1.0 K01951:guaA, GMPS; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] 0.9861111111111112 none 1.0 448522 523317 497817 628570 568490 594140 506007 417516 0 0 0 0 0 392101 510047 0 485684 350097 491087 551666 497337 768849 680344 280408 810312 445218 249513 905071 490607 0 0 458910 267572 438381 0 439509 375551 543354 467270 720132 497253 733069 538800 534973 786621 1333515 0 0 0 0 0 933755 373240 0 637365 1209875 956192 733447 233486 457216 636693 756518 1034229 700352 641056 911448 791637 0 0 538315 430821 803374 267907 621763 592804 257282 557409 680340 436738 396691 241483 380392 304417 494562 0 0 0 0 0 267234 786494 0 422637 316895 533353 428643 547676 536405 400762 283343 769218 285921 565713 506376 273148 0 0 549977 579813 593374 734408 262768 428230 471988 585281 456732 620203 626930 650073 603660 648267 604077 0 0 0 0 0 582497 555166 0 621649 354607 683800 803913 743759 463569 474625 596038 647991 521879 298775 441613 454975 0 0 621000 545801 490783 389266 571566 569577 688284 192600 0 0 0 175279 189116 0 136564 0 0 0 0 0 266673 191761 0 219318 83925 246919 198194 0 298331 263237 0 208059 0 156502 377927 0 0 0 0 401098 227711 321697 273012 194156 190296 +(Gln->pyro-Glu)QPFPGPGLGVR MGYG000000177_00259;MGYG000001622_03026;MGYG000000650_02217;MGYG000001564_01569;MGYG000002478_04002;MGYG000001311_04643;MGYG000001374_02303;MGYG000001346_03291;MGYG000002218_01878;MGYG000002685_01245;MGYG000000383_00024;MGYG000002438_02747;MGYG000003351_04375;MGYG000000198_03851;MGYG000000044_00075;MGYG000001617_00853;MGYG000001617_00899;MGYG000000172_03526;MGYG000001345_00044;MGYG000000222_01345;MGYG000000312_02550;MGYG000000032_05843;MGYG000000150_00351;MGYG000001780_04179;MGYG000001615_05534;MGYG000000029_03508;MGYG000000121_02100;MGYG000004863_00474;MGYG000000622_01763;MGYG000000378_00210;MGYG000000198_00134;MGYG000004735_00074;MGYG000000174_03354;MGYG000000138_02270;MGYG000001651_01803;MGYG000000098_03146;MGYG000000013_02510;MGYG000002727_00995;MGYG000004769_01556;MGYG000001619_01813;MGYG000001356_00700;MGYG000004899_02570;MGYG000003324_00600;MGYG000001493_04160;MGYG000002455_02568;MGYG000002004_00749;MGYG000000133_02443;MGYG000004630_02361;MGYG000000179_04192;MGYG000004762_01920 domain d__Bacteria 1.0 COG0519@1|root,COG0519@2|Bacteria,4NZSX@976|Bacteroidetes,2FNJE@200643|Bacteroidia,4AMZI@815|Bacteroidaceae 0.32 186801|Clostridia 0.64 F 1.0 Catalyzes the synthesis of GMP from XMP 0.32 - 0.8 - 0.68 6.3.5.2 1.0 ko:K01951 1.0 ko00230,ko00983,ko01100,map00230,map00983,map01100 1.0 M00050 1.0 R01230,R01231,R08244 1.0 RC00010,RC00204 1.0 ko00000,ko00001,ko00002,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 GATase,GMP_synt_C,NAD_synthase 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000177_00259 0.02 GMP synthase (glutamine-hydrolyzing). GMP synthetase (glutamine-hydrolyzing). Involved in the de novo biosynthesis of guanosine nucleotides.-!-An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain.-!-The enzyme can catalyze the second reaction alone in the presence of ammonia.-!-Formerly EC 6.3.4.1. ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways 1.0 K01951:guaA, GMPS; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] 1.0 none 1.0 208154 0 170296 431935 0 0 203270 0 387012 0 0 0 0 251292 0 347689 0 0 363276 0 0 0 0 0 386576 1008697 0 0 0 0 0 0 200256 274285 0 318037 369036 195714 177121 0 173870 297591 0 0 448598 0 169205 0 0 0 0 338443 0 849568 0 0 280859 0 0 0 0 0 1722362 516773 0 0 0 0 0 0 85456 1003632 0 282376 151273 1081819 192557 0 0 0 0 0 253569 0 0 0 0 0 0 0 0 0 0 0 181988 0 0 0 0 0 102137 0 0 0 0 0 0 0 0 0 0 0 0 0 178982 0 222980 349019 0 0 92963 0 0 0 0 0 0 195815 0 772831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374564 0 0 0 0 0 564542 0 494846 747287 0 0 566394 0 531953 0 0 0 0 734981 0 512931 0 0 670091 0 0 0 0 0 638145 621119 0 0 0 0 0 0 842343 706458 0 557551 649693 572771 +(Gln->pyro-Glu)QPSDEKPTYWEK MGYG000000022_00469 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,3WHNA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 purine-nucleoside phosphorylase 1.0 deoD 1.0 - 1.0 2.4.2.1 1.0 ko:K03784 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00469 1.0 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Nicotinate and nicotinamide metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K03784:deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 755385 0 0 0 0 215947 0 0 0 0 336532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 906773 0 0 0 0 635194 0 0 0 0 446476 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QPSNSSTGELDTTALNYNK MGYG000002492_00430;MGYG000002670_00445 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,25UXG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00430 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1237560 0 0 0 0 499243 0 0 0 0 1071953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QPSQEELSIAR MGYG000002506_00321;MGYG000002494_01268;MGYG000002477_03573;MGYG000003372_00988;MGYG000002534_01961 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria 0.8 1236|Gammaproteobacteria 1.0 S 1.0 Belongs to the WrbA family 0.8 wrbA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016043,GO:0016491,GO:0016651,GO:0016655,GO:0022607,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 1.6.5.2 1.0 ko:K03809 1.0 ko00130,ko01110,map00130,map01110 1.0 - 1.0 R02964,R03643,R03816 1.0 RC00819 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FMN_red 1.0 - 1.0 AA6 1.0 AA6 1.0 - 1.0 MGYG000002506_00321 0.2 NAD(P)H dehydrogenase (quinone). vitamin-K reductase. The enzyme catalyzes a two-electron reduction and has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone.-!-The animal, but not the plant, form of the enzyme is inhibited by dicoumarol.-!-Formerly EC 1.6.99.2. (1) a quinone + H(+) + NADH = a quinol + NAD(+). (2) a quinone + H(+) + NADPH = a quinol + NADP(+). 1.0 1.0 1.0 1.0 Ubiquinone and other terpenoid-quinone biosynthesis|Biosynthesis of secondary metabolites 1.0 K03809:wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 346867 0 257420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1580411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1604371 0 1189997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QPSQEEMEK MGYG000000022_02066;MGYG000001255_00882;MGYG000000078_01938;MGYG000002223_01610;MGYG000003656_01457;MGYG000000274_02973;MGYG000000389_02289;MGYG000000195_00502;MGYG000000089_00814;MGYG000002098_00269;MGYG000002552_01350;MGYG000003702_01345;MGYG000002517_00745;MGYG000003921_02148;MGYG000000278_00036;MGYG000000187_00590;MGYG000002492_02033;MGYG000000154_00158;MGYG000000589_00988;MGYG000000271_02213;MGYG000002651_01773;MGYG000001300_01639;MGYG000003694_01134;MGYG000001652_01458 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia 0.375 186801|Clostridia 1.0 C 0.7083333333333334 alcohol dehydrogenase 0.4166666666666667 adh 0.7083333333333334 - 0.7083333333333334 - 0.5833333333333334 - 0.5833333333333334 - 0.5833333333333334 - 0.7083333333333334 - 0.5833333333333334 - 0.5833333333333334 - 0.5833333333333334 - 1.0 - 1.0 - 1.0 Fe-ADH 0.5833333333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_02066 0.041666666666666664 - - - - 0.5833333333333334 0.5833333333333334 0.5833333333333334 0.5833333333333334 - 0.5833333333333334 - 0.5833333333333334 none 1.0 561048 0 361562 716760 0 0 0 589547 637597 672047 0 0 0 692297 801224 0 0 657439 564334 541116 0 0 1280760 0 742496 581652 596255 1478841 0 0 192757 0 364289 0 464399 605002 526924 403300 439982 0 436662 601645 0 0 0 396851 554161 236405 0 0 0 529850 561185 0 0 699245 551511 487826 0 0 758599 0 86525 483542 481881 1083909 0 0 362302 0 574782 0 253853 320761 448399 434586 676862 0 543615 502690 0 0 0 523411 464101 423635 0 0 0 645997 595502 0 0 652537 599103 466177 0 0 693652 0 643096 726505 633138 686285 0 0 521474 0 494850 0 382245 583003 671710 455209 804034 0 432470 785204 0 0 0 886593 966924 540950 0 0 0 1039889 981484 0 0 364979 869471 949669 0 0 526690 0 1352109 1262458 995350 517124 0 0 418769 0 465910 0 1157622 934645 1212108 444791 597195 0 746303 0 0 0 0 523964 601574 856822 0 0 0 797253 818934 0 0 903663 693235 522969 0 0 1002613 0 1132381 946597 987166 1267570 0 0 489917 0 781428 0 700197 1391921 1052318 722927 +(Gln->pyro-Glu)QPSQEEMEKLLK MGYG000002517_00745;MGYG000003921_02148;MGYG000000271_02213;MGYG000001300_01639;MGYG000002098_00269;MGYG000001652_01458 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia 0.5 186801|Clostridia 1.0 C 0.8333333333333334 alcohol dehydrogenase 0.5 adh 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 Fe-ADH 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00745 0.16666666666666666 - - - - 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QPVKEPLQTGIK MGYG000002272_00433;MGYG000004464_00315;MGYG000000195_00672;MGYG000002794_01431;MGYG000000039_00039;MGYG000002040_00951;MGYG000004679_00015;MGYG000001300_02370;MGYG000000022_01422;MGYG000003291_01611;MGYG000001655_01488;MGYG000003899_00594;MGYG000002545_01159;MGYG000002610_02019;MGYG000003697_01834;MGYG000002651_01642 domain d__Bacteria 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae 0.8125 186801|Clostridia 0.8125 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 0.8125 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 0.8125 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000002272_00433 0.0625 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 678440 713656 765058 0 0 595472 492454 0 0 0 396691 0 0 861878 0 0 0 0 917585 915609 0 678437 0 627238 627725 716705 696588 0 0 0 580345 0 925228 0 0 0 756058 596938 1320607 1055295 1316096 0 0 1149287 1460947 0 0 0 869072 0 0 1481354 0 0 0 0 1952623 1180752 0 811585 0 919525 1912486 1390866 1310724 0 0 0 1091653 0 1268472 0 0 0 1558062 1312964 0 351627 565694 0 0 0 462414 0 0 0 0 0 0 0 0 0 0 0 485179 372181 0 0 0 0 0 498777 0 0 0 0 501631 0 0 0 0 0 594597 0 830723 192637 1551252 0 0 1280576 1328012 0 0 0 1126050 0 0 1221927 0 0 0 0 1624191 1156216 0 983968 0 1045833 1386663 1247156 916245 0 0 0 1143554 0 1352722 0 0 0 1185315 1362082 0 277695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 329040 0 270396 0 0 0 0 0 +(Gln->pyro-Glu)QPVKEPLQTGLK MGYG000001975_01278;MGYG000004464_00315;MGYG000001056_00148;MGYG000004758_01459;MGYG000002040_00951;MGYG000002224_01680;MGYG000004679_00015;MGYG000004456_02417;MGYG000001300_02370;MGYG000003291_01611;MGYG000000022_01422;MGYG000003812_00624;MGYG000003899_00594;MGYG000002545_01159;MGYG000002960_01412;MGYG000003697_01834;MGYG000002051_00534;MGYG000002651_01642 domain d__Bacteria 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae 0.5 976|Bacteroidetes 0.5 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 - 0.5 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 0.5 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000001975_01278 0.05555555555555555 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1361697 0 0 0 0 0 0 0 0 0 0 0 0 1663853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QPVNQPLQTGLK MGYG000001661_02014;MGYG000004876_02547;MGYG000002549_01706;MGYG000002281_02651;MGYG000002171_00080;MGYG000000196_02101;MGYG000002478_03339;MGYG000001313_01542;MGYG000001346_00381;MGYG000004797_02195;MGYG000003201_00723;MGYG000000243_00489;MGYG000000013_03749;MGYG000001378_01038 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,2FM4H@200643|Bacteroidia,4AKBP@815|Bacteroidaceae 0.9285714285714286 976|Bacteroidetes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 - 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000001661_02014 0.07142857142857142 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456909 0 0 0 0 475072 0 0 0 0 482808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375058 0 0 0 0 264796 0 0 0 0 256284 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QPVQVNEAAGFVVNR MGYG000002224_01332;MGYG000001255_01113;MGYG000002272_01496;MGYG000003166_01335 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002224_01332 0.25 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1793302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1294415 0 0 0 0 0 0 0 0 0 2204077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1165966 0 0 0 0 0 0 0 0 0 1838617 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQAAGTTTLQPK MGYG000002293_00972;MGYG000002080_02252;MGYG000003697_01780;MGYG000002834_01787;MGYG000002960_00648 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG3637@1|root,COG3637@2|Bacteria,4NR9K@976|Bacteroidetes,2FU05@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 Outer membrane protein beta-barrel domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OMP_b-brl,OMP_b-brl_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00972 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 138631 296850 0 0 0 0 0 0 0 0 366633 0 0 0 0 404166 0 0 0 0 0 0 0 0 0 0 202280 0 0 0 0 0 0 174120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 767127 0 0 0 0 0 210738 0 0 0 0 0 0 1651981 0 0 0 0 0 0 0 0 0 219566 0 0 212739 0 0 0 0 0 0 196707 2341096 2297096 9975608 0 3739901 7427440 0 3243897 2050589 0 4133484 4555000 5090869 0 0 2607543 1768691 12571075 0 0 1469337 8175808 16646143 8906277 2636181 3206136 0 9603660 0 0 4194797 3605970 9651290 4009694 3566198 3233131 2330377 8561908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQDAALAAK MGYG000003693_02255 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_02255 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1525934 0 0 0 0 2591222 0 0 0 0 1647253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378513 0 0 0 0 331589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQEFDIIHAHDWLTYPAGVHAK MGYG000002560_03190;MGYG000001346_03285;MGYG000001661_02656;MGYG000000243_01312;MGYG000002171_02171;MGYG000001378_02334;MGYG000004797_02601;MGYG000002478_03183 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0438@1|root,COG0438@2|Bacteria,4NEWR@976|Bacteroidetes,2FMW0@200643|Bacteroidia,4AKN5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Glycosyltransferase, group 1 family protein 1.0 gmhA 1.0 - 1.0 2.4.1.346 1.0 ko:K13668 1.0 - 1.0 - 1.0 R11703,R11704 1.0 - 1.0 ko00000,ko01000,ko01003 1.0 - 1.0 GT4 1.0 - 1.0 Glyco_trans_4_4,Glyco_transf_4,Glyco_transf_5,Glycos_transf_1,SIS_2 1.0 - 1.0 GT4 1.0 GT4 1.0 GT4 1.0 MGYG000002560_03190 0.125 phosphatidyl-myo-inositol dimannoside synthase. mannosyltransferase. The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs). (1) a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D- myo-inositol] + GDP-alpha-D-mannose = a 2,6-O-bis(alpha-D- mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+). (2) a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl- (1<->6)-D-myo-inositol] + GDP-alpha-D-mannose = 2-O-(alpha-D-mannosyl)-6- O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+). 1.0 1.0 1.0 1.0 - 1.0 K13668:pimB; phosphatidyl-myo-inositol dimannoside synthase [EC:2.4.1.346] 1.0 none 1.0 0 0 104570 402986 578165 0 0 343053 0 0 0 372487 948370 0 0 0 0 269167 0 0 0 0 429068 0 0 0 0 844497 0 975686 1361036 872668 840838 0 2044045 0 0 683762 0 0 362334 306795 359768 0 0 807268 0 0 0 770934 1316075 0 0 0 0 0 0 0 0 0 330921 0 0 0 0 0 0 2083626 0 932664 1859621 0 0 0 0 0 0 0 0 0 2591025 0 0 0 0 0 0 0 0 0 0 0 0 1608991 0 0 0 0 921116 0 0 0 0 2372641 0 0 0 1398992 0 0 0 0 0 1680125 0 0 0 0 0 0 0 0 0 0 0 0 66207 0 0 0 0 1044837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1466083 0 0 128104 0 0 0 0 0 +(Gln->pyro-Glu)QQEIDYLNEHGFAADFTK MGYG000002171_00958;MGYG000004797_01307;MGYG000002478_00672;MGYG000000243_02714 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,2FMRA@200643|Bacteroidia,4AKJP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 argininosuccinate synthase 1.0 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_00958 0.25 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids|Fluid shear stress and atherosclerosis 1.0 K01940:argG, ASS1; argininosuccinate synthase [EC:6.3.4.5] 1.0 none 1.0 0 0 634806 0 911379 0 0 0 0 0 0 0 758184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 781354 0 0 0 0 748119 0 0 0 0 0 0 0 0 0 0 0 0 1549896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1249574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9747491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQFDKPSVLNR MGYG000002478_00821;MGYG000000243_01995 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,2FUNX@200643|Bacteroidia,4ARQ8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS21 family 1.0 rpsU 1.0 - 1.0 - 1.0 ko:K02970 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S21 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00821 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02970:RP-S21, MRPS21, rpsU; small subunit ribosomal protein S21 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 728746 0 0 0 0 677082 0 0 0 0 814864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2051992 0 0 0 0 469538 0 0 0 0 2270414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1341333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3894747 0 0 0 0 4258513 0 0 0 0 3691626 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQFDKPSVTK MGYG000000196_03967;MGYG000001337_03914;MGYG000001378_05049;MGYG000002561_02155;MGYG000004748_01295;MGYG000001345_04677;MGYG000000098_02024;MGYG000001346_01539 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,2FUNX@200643|Bacteroidia,4ARQ8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS21 family 1.0 rpsU 1.0 - 1.0 - 1.0 ko:K02970 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S21 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_03967 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02970:RP-S21, MRPS21, rpsU; small subunit ribosomal protein S21 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327363 0 0 0 0 523877 0 0 0 0 315337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 671357 0 0 0 0 742320 0 0 0 0 736556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 500728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQGNLDYTDLYDKR MGYG000002549_02817;MGYG000000098_00813;MGYG000000196_04138;MGYG000001433_02399;MGYG000002281_01804;MGYG000001345_00398 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,4AN6T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG2086 Electron transfer flavoprotein beta subunit 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_02817 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 637410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 503599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQHSDVRPSR MGYG000003372_00912;MGYG000002494_02547;MGYG000002535_03948 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0432@1|root,COG0432@2|Bacteria,1RH13@1224|Proteobacteria,1S3VP@1236|Gammaproteobacteria,3XNQ9@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 1.0 S 1.0 Uncharacterised protein family UPF0047 0.6666666666666666 yjbQ 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 UPF0047 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003372_00912 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 826875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 968507 0 708212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 821031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQIASDIEFIR MGYG000001313_01931;MGYG000004185_01081;MGYG000000105_02066;MGYG000001346_03599;MGYG000003681_00353 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4372@1|root,COG4372@2|Bacteria,4NJGZ@976|Bacteroidetes,2G2H0@200643|Bacteroidia,4AKNU@815|Bacteroidaceae 0.6 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_01931 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181693 0 0 0 444169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 145384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQIASDIEFIRK MGYG000001313_01931;MGYG000004185_01081;MGYG000000105_02066;MGYG000001346_03599;MGYG000003681_00353;MGYG000004748_03718 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4372@1|root,COG4372@2|Bacteria,4NJGZ@976|Bacteroidetes,2G2H0@200643|Bacteroidia,4AKNU@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_01931 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 294907 361196 0 0 0 515063 0 370574 465861 710082 0 688769 309847 427687 540961 556894 398271 709503 0 0 0 398284 460863 823290 0 277072 807179 540097 703809 0 627018 0 488151 683952 410279 292035 306398 0 0 386709 504044 0 0 1550324 0 355819 1439277 0 0 0 699078 0 605717 1386100 0 468993 0 0 673654 0 962828 646375 0 713247 694176 629981 0 0 0 0 0 0 0 0 848109 1211439 772352 712886 808231 930390 0 1032903 858352 920991 675233 991950 0 1141797 698254 820794 757045 712677 897834 1701357 0 0 879360 607616 1212662 1033332 813998 660424 698803 1171597 718468 0 961572 0 643913 822077 935235 880816 857831 761557 568552 256509 504948 614791 0 363943 620467 446871 536600 592580 0 814908 570988 399301 544477 518763 532267 275439 0 0 507754 493344 619422 321003 713927 572615 582364 221102 558628 0 527561 0 532529 1057792 768138 407369 456373 352088 0 382629 251517 525721 0 275663 473634 749806 0 0 0 210065 0 437290 435060 418704 291442 504192 0 0 486446 0 530643 0 332961 188653 278239 657659 0 0 467676 0 0 620877 611621 0 0 414731 +(Gln->pyro-Glu)QQIEEATSDYDREK MGYG000002515_04060;MGYG000002507_03180;MGYG000002494_02676;MGYG000002385_03148;MGYG000002323_03824;MGYG000002506_03866 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,3XN1I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002515_04060 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 567959 1170694 507501 991133 603201 1430509 1262869 1628085 679573 1302080 0 492260 633769 1165950 962762 513129 637975 0 930737 731400 1116066 1910919 0 1949913 1374218 650697 1105317 0 620888 1359771 582046 752895 741773 1265877 1471793 1097151 819693 795082 3087142 4538722 4434915 2827784 3720221 9629651 2872657 2694430 3088819 5397005 1487956 2257412 2490321 3182195 3054862 3209007 6000048 0 3885750 2644950 3382781 8139174 0 7144749 4340526 2912440 2329860 0 5477547 3836772 1743821 3160315 4463314 3082513 2530257 3036077 2365964 4689168 1071747 924797 995492 540834 837166 2070172 1167725 1336457 876164 1157174 989555 566379 726309 980917 1052159 881530 757337 0 986147 618214 976189 1136407 0 1577066 1370444 574149 1119415 0 854442 1050834 873016 679222 1010086 1298037 1043328 1129024 694112 880481 994398 995953 1195656 1060179 960070 1469916 1279519 1376707 1096182 1506771 889845 1035120 1098540 1076406 175240 852433 1046320 0 615544 954660 996214 1801860 0 1168405 1245676 1119127 991750 0 1206028 1060709 617750 1086915 1171810 1616400 1550796 1285185 882336 933776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQIEEATSDYDREKLQER MGYG000002515_04060;MGYG000002494_02676;MGYG000002506_03866 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1MURR@1224|Proteobacteria,1RMTB@1236|Gammaproteobacteria,3XN1I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009987,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019058,GO:0019068,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0044183,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0097159,GO:0097367,GO:0101031,GO:1901265,GO:1901363,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002515_04060 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 865630 0 0 0 893329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 787374 0 944139 0 0 0 0 0 0 0 0 0 889697 1123055 0 0 0 0 505530 0 0 0 860705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040508 0 486149 0 0 0 0 0 0 0 0 0 363316 0 0 0 0 0 813845 0 0 0 808001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363631 0 655708 0 0 0 0 0 0 0 0 0 454834 722717 0 0 0 0 340920 0 0 0 735342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 649876 0 530657 0 0 0 0 0 0 0 0 0 788185 699228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQIREDIPQVR MGYG000001642_01002;MGYG000000188_00085;MGYG000002919_00610;MGYG000002970_00265;MGYG000003274_00525;MGYG000002775_01392;MGYG000002050_00246;MGYG000003266_00519;MGYG000002961_01431;MGYG000004681_00352;MGYG000000802_00135 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4CXT4@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001642_01002 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQIVSQHVAAAPEFC(Carbamidomethyl)YR MGYG000001300_02158 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000001300_02158 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 896932 0 0 806876 0 0 964383 1081000 1095922 0 0 0 0 441951 377647 0 925694 0 953287 631779 0 0 0 0 597987 852908 1123290 0 0 0 0 0 0 641919 0 650639 944686 0 625148 0 0 999470 0 0 724524 542105 1023580 0 0 0 0 831318 941481 0 850991 0 844001 625740 0 0 0 0 954853 794153 860912 0 0 0 0 0 0 662966 0 725845 719564 0 404016 0 0 647392 0 0 705942 540977 835205 0 0 0 0 0 724566 0 865016 0 362801 585357 0 0 0 0 284733 631666 348187 0 0 0 0 0 0 506950 0 605933 581619 0 513381 0 0 383179 0 0 771942 840260 630670 0 0 0 0 592364 168326 0 156907 0 289954 778705 0 0 0 0 821464 726904 826469 0 0 0 0 0 0 823334 0 1018323 440243 0 457161 0 0 591284 0 0 292961 244717 537315 0 0 0 0 0 0 0 623914 0 0 545136 0 0 0 0 511230 297365 460290 0 0 0 0 0 0 0 0 434559 931152 0 +(Gln->pyro-Glu)QQKPVVVEQVDIIQVQDK MGYG000001313_02966 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia,4AMCZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_02966 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1109725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1860863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQLSQGTIDKLNESYDLMK MGYG000000164_00292 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,36EW8@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 S 1.0 basic membrane 1.0 tmpC 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_00292 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07335:bmpA, bmpB, tmpC; basic membrane protein A and related proteins 1.0 none 1.0 0 0 0 0 0 0 0 0 980545 1061850 0 0 924917 0 960520 763204 0 0 0 0 0 0 0 0 875531 0 934019 0 0 0 0 0 0 0 710874 741258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18552888 0 0 0 +(Gln->pyro-Glu)QQNAEAEKR MGYG000002494_03015 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,3ZJ1Q@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 C 1.0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) 1.0 aceF 1.0 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 1.0 2.3.1.12 1.0 ko:K00627 1.0 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 1.0 M00307 1.0 R00209,R02569 1.0 RC00004,RC02742,RC02857 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iETEC_1333.ETEC_0111,iSSON_1240.SSON_0123,iYL1228.KPN_00119 1.0 2-oxoacid_dh,Biotin_lipoyl,E3_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03015 1.0 dihydrolipoyllysine-residue acetyltransferase. transacetylase X. A multimer (24-mer or 60-mer, depending on the source) of this enzyme forms the core of the pyruvate dehydrogenase multienzyme complex, and binds tightly both EC 1.2.4.1 and EC 1.8.1.4.-!-The lipoyl group of this enzyme is reductively acetylated by EC 1.2.4.1, and the only observed direction catalyzed by EC 2.3.1.12 is that where the acetyl group is passed to coenzyme A. acetyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = CoA + N(6)- [(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00627:DLAT, aceF, pdhC; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 543930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQNLDAIHDTVHEMC(Carbamidomethyl)KDEAR MGYG000002438_03105;MGYG000001489_02852;MGYG000000222_03431 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG1592@1|root,COG1592@2|Bacteria,4NJ7V@976|Bacteroidetes,2FP1G@200643|Bacteroidia,22UC5@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Rubrerythrin 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03105 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193347 0 0 0 0 0 0 0 0 0 0 260692 0 0 0 0 0 0 0 0 0 0 202621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246495 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 639389 0 0 0 0 0 0 0 0 0 0 652049 0 0 0 0 0 0 +(Gln->pyro-Glu)QQNPVTGSGGMFK MGYG000002926_00666;MGYG000002882_00083;MGYG000002794_00765;MGYG000002156_01166;MGYG000001733_00674;MGYG000002720_00859;MGYG000004196_01675;MGYG000002143_01957;MGYG000004475_00754 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia 0.8888888888888888 186801|Clostridia 1.0 C 0.8888888888888888 alcohol dehydrogenase 0.8888888888888888 kdd 0.8888888888888888 - 1.0 1.4.1.11 0.8888888888888888 ko:K18012 0.8888888888888888 ko00310,map00310 0.8888888888888888 - 0.8888888888888888 R03349 0.8888888888888888 RC00888 0.8888888888888888 ko00000,ko00001,ko01000 0.8888888888888888 - 1.0 - 1.0 - 1.0 ADH_zinc_N 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_00666 0.1111111111111111 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 Lysine degradation 0.8888888888888888 K18012:kdd; L-erythro-3,5-diaminohexanoate dehydrogenase [EC:1.4.1.11] 0.8888888888888888 none 1.0 548474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333374 536081 0 0 0 0 0 0 0 0 0 0 663032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480799 395028 0 0 0 0 0 0 0 0 0 0 498260 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQPELGEKLSPK MGYG000000074_01424 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0578@1|root,COG0578@2|Bacteria,4NEYG@976|Bacteroidetes,2FN2W@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 C-terminal domain of alpha-glycerophosphate oxidase 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,DAO_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01424 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358410 0 0 0 0 0 0 0 0 0 0 850331 0 +(Gln->pyro-Glu)QQQELQALQQK MGYG000002478_02506;MGYG000004797_02614;MGYG000002560_00938 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2825@1|root,COG2825@2|Bacteria,4NQGG@976|Bacteroidetes,2FPTR@200643|Bacteroidia,4AMZ6@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 - 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02506 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 776129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQQIETLQAELASK MGYG000000243_03188;MGYG000002478_01929;MGYG000004797_03694 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4372@1|root,COG4372@2|Bacteria,4NMT7@976|Bacteroidetes,2FNI1@200643|Bacteroidia,4AVYV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Transposase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03188 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 812105 0 0 0 0 0 0 0 0 0 715454 0 0 0 0 0 0 0 0 252406 0 313520 0 0 0 0 0 0 0 0 801205 0 0 0 0 758461 0 0 344231 0 0 230791 0 0 0 0 0 0 647095 0 0 0 0 0 0 0 0 330732 0 0 0 0 0 0 0 0 0 0 326283 0 0 0 0 250788 0 0 137528 0 0 446539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQQMVQK MGYG000000195_01571;MGYG000001157_00999;MGYG000000084_00625;MGYG000002619_02237;MGYG000001300_00293;MGYG000004732_01390;MGYG000001255_01112;MGYG000002040_01717 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WI1F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000195_01571 0.125 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 846371 1097606 1480229 1696350 0 499166 974688 1089234 0 1199761 1210156 1151315 1539032 1115204 1432292 603488 0 0 2229659 1861791 0 1183352 803365 930973 1829504 1538827 1173101 1213059 0 768017 853784 691888 1309801 2013998 750408 977036 914730 1124944 1744995 1860648 1605326 1786146 1498086 2134311 2613085 969589 0 518388 1369270 2285294 1813108 2273402 1901455 1453687 0 1373542 3082019 2500167 0 1640296 1586545 2349758 2537854 2236472 2065415 1533734 0 2049842 2531254 2179899 1673005 1747303 669644 1203356 1765953 1807155 0 0 0 570433 0 0 921621 0 0 611348 0 0 0 0 0 0 0 849222 0 0 0 0 667480 581585 0 863564 0 0 0 0 0 626147 0 0 0 0 0 0 0 1236879 2022398 793626 1679592 1417447 1705006 0 0 0 1664106 1863284 1545985 711062 603168 1426559 0 0 1225882 941669 0 1042938 513395 1343601 0 0 0 1353738 0 1034941 1747935 664612 2157484 1056303 0 127927 733362 2153869 0 0 0 206215 261077 0 0 0 0 0 0 281847 0 0 0 0 0 0 0 255909 0 0 0 0 0 0 0 1086599 0 0 0 105748 0 0 0 0 100263 0 +(Gln->pyro-Glu)QQVSLQDVANR MGYG000002478_02149 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,4NETS@976|Bacteroidetes,2FNBA@200643|Bacteroidia,4AM82@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EU 1.0 Peptidase, S9A B C family, catalytic domain protein 1.0 dpp 1.0 - 1.0 3.4.14.5 1.0 ko:K01278 1.0 ko04974,map04974 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 1.0 - 1.0 - 1.0 - 1.0 DPPIV_N,PD40,Peptidase_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02149 1.0 dipeptidyl-peptidase IV. Xaa-Pro-dipeptidylaminopeptidase. A membrane-bound serine-type peptidase in mammals.-!-EC 3.4.14.11 catalyzes a similar reaction.-!-Belongs to peptidase family S9B. Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline. 1.0 1.0 1.0 1.0 Protein digestion and absorption 1.0 K01278:DPP4, CD26; dipeptidyl-peptidase 4 [EC:3.4.14.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 584526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 678158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQYTAVKIEK MGYG000001687_00102;MGYG000001310_01505;MGYG000002279_00674;MGYG000001315_03087 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,27VNF@189330|Dorea 0.5 186801|Clostridia 1.0 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 - 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001687_00102 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02888:RP-L21, MRPL21, rplU; large subunit ribosomal protein L21 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QQYTQVKIEK MGYG000004735_00428 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 - 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00428 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02888:RP-L21, MRPL21, rplU; large subunit ribosomal protein L21 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 886649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QREELAEQIK MGYG000000018_02208 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus|s__Coprococcus eutactus|m__MGYG000000018 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36F8M@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 formate acetyltransferase 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000018_02208 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 729935 0 0 0 0 0 0 0 0 0 414292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QREELAEQIKR MGYG000000018_02208 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus|s__Coprococcus eutactus|m__MGYG000000018 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36F8M@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 formate acetyltransferase 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000018_02208 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1652022 0 0 0 0 1015832 0 0 0 0 1653296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103454 0 0 0 0 252809 0 0 0 0 309774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QREELAEQIR MGYG000001315_01877 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25VH6@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01877 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QRELNNK MGYG000002438_02216 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0255@1|root,COG0255@2|Bacteria,4NUSC@976|Bacteroidetes,2FUJB@200643|Bacteroidia,22YR4@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uL29 family 1.0 rpmC 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02904 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L29 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02216 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02904:RP-L29, rpmC; large subunit ribosomal protein L29 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 631084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 840414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 229823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1179507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QREQLLEQLTK MGYG000003122_00373;MGYG000002775_00629;MGYG000002970_00844;MGYG000003266_00492;MGYG000002961_01179;MGYG000004681_01377;MGYG000002919_00637;MGYG000001718_00865;MGYG000001636_00787;MGYG000002947_00265;MGYG000001567_01555;MGYG000000188_00058;MGYG000002050_00219;MGYG000001642_00367 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4CW7U@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 integration host factor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003122_00373 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 820545 0 0 0 0 0 0 0 0 0 0 0 0 0 540008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285554 0 0 0 0 0 0 0 0 0 0 0 0 0 1339502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QRGDWDQAK MGYG000000198_03565;MGYG000004087_01554;MGYG000002966_00469;MGYG000000255_00860 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,21YYA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein-like domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_03565 0.25 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 944902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 861769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040506 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QRKPGSLGASSYPSR MGYG000000074_01962;MGYG000002082_00487;MGYG000000170_00041;MGYG000000053_00693;MGYG000003539_00291;MGYG000001415_01617 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae 1.0 COG0087@1|root,COG0087@2|Bacteria,4NEAN@976|Bacteroidetes,2FMS5@200643|Bacteroidia,22U9U@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit 1.0 rplC 1.0 - 1.0 - 1.0 ko:K02906 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01962 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02906:RP-L3, MRPL3, rplC; large subunit ribosomal protein L3 1.0 none 1.0 0 0 0 0 0 179386 0 182242 0 172541 316395 0 0 0 262389 0 0 0 239121 209491 182584 0 0 316327 0 0 0 0 0 198565 0 0 0 0 0 0 0 0 414517 0 0 364417 200849 247391 0 274551 489943 556606 185877 0 175393 0 391706 0 0 0 288310 333235 342687 224758 0 327095 0 271268 0 0 0 255578 0 0 0 0 255862 0 400592 0 283348 0 0 298387 0 368536 0 603885 285558 0 0 0 0 0 256795 0 0 0 0 341813 0 220995 0 216918 0 256446 0 0 0 275522 0 0 0 0 0 0 300234 0 0 0 0 0 194750 541070 0 0 0 0 377660 0 0 0 0 0 0 0 0 0 0 448033 0 418210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1200669 0 0 1730864 1469182 1414663 0 1047790 1309602 1365056 1140556 0 1272111 0 1123217 0 0 0 1681142 1568100 979343 1013012 0 1120725 0 2068946 0 0 0 1525185 0 0 0 0 1795689 0 1838145 0 +(Gln->pyro-Glu)QRPDDFDKDEPVEFPLNR MGYG000001562_01034;MGYG000001546_01498;MGYG000003279_00890;MGYG000001420_00047;MGYG000000003_02437 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0545@1|root,COG0545@2|Bacteria,4NDW4@976|Bacteroidetes,2FNCK@200643|Bacteroidia,22UI6@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 1.0 fklB 1.0 - 1.0 5.2.1.8 1.0 ko:K03772,ko:K03773 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,FKBP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001562_01034 0.2 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K03772:fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]|K03773:fklB; FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC:5.2.1.8] 1.0 none 1.0 780216 0 335546 0 334457 945686 679107 0 2056187 0 0 1497766 762414 1192825 0 0 1218391 0 1112885 0 1059599 1372302 0 807641 954758 1128270 1593802 0 773816 2173810 0 0 595579 246305 0 0 1178731 258768 0 0 347014 0 369147 1042589 0 0 361015 0 0 165175 0 335070 0 0 698691 0 0 0 269350 955685 0 0 0 0 0 0 0 368751 0 0 0 0 0 0 0 0 915372 0 1229467 0 1072142 373088 678714 0 1153400 0 0 1061440 597725 1001800 0 0 811149 0 895186 0 1074480 0 0 352895 1018235 868125 810322 0 824041 1413871 0 0 946642 1573268 0 0 767201 1627917 416604 0 415260 0 411424 518432 494152 0 549973 0 0 707408 465067 547206 0 0 427652 0 1545617 0 397852 0 0 478341 1060464 587588 324478 0 508935 431007 0 0 508595 426022 0 0 576342 436263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299252 0 0 0 0 141288 0 0 0 0 0 301032 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QRPGAGSAVSDDEIK MGYG000000243_00735 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG4771@2|Bacteria,4PKE0@976|Bacteroidetes,2G3DW@200643|Bacteroidia,4AME6@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Psort location OuterMembrane, score 10.00 1.0 - 1.0 - 1.0 - 1.0 ko:K02014 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,MipA,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00735 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02014:TC.FEV.OM; iron complex outermembrane recepter protein 1.0 none 1.0 0 0 854417 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1087839 0 0 0 0 1073105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QRPLWASTGTK MGYG000001292_01122;MGYG000003683_00464;MGYG000002459_00838;MGYG000002469_01093 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001292_01122 0.25 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00616:TALDO1, talB, talA; transaldolase [EC:2.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2046291 0 0 0 0 412711 0 0 0 0 1530223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QRPYDIIADPTVTPK MGYG000000196_03453;MGYG000001345_02362 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,4AK9W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrA 1.0 - 1.0 1.6.5.8 1.0 ko:K00346 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQRA,NQRA_SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_03453 0.5 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 - 1.0 K00346:nqrA; Na+-transporting NADH:ubiquinone oxidoreductase subunit A [EC:7.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 748161 0 0 229845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733004 0 0 662063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281720 0 0 359524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262815 0 0 368987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QRPYDIVAAPLDTPR MGYG000002438_03483 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,22XC8@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrA 1.0 - 1.0 1.6.5.8 1.0 ko:K00346 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQRA,NQRA_SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03483 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 - 1.0 K00346:nqrA; Na+-transporting NADH:ubiquinone oxidoreductase subunit A [EC:7.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 344872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 814793 0 0 0 0 0 0 0 0 670127 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QRPYDVIADPTIAPK MGYG000001306_00758 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,4AK9W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrA 1.0 - 1.0 1.6.5.8 1.0 ko:K00346 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQRA,NQRA_SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_00758 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 - 1.0 K00346:nqrA; Na+-transporting NADH:ubiquinone oxidoreductase subunit A [EC:7.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290413 0 0 0 0 640984 0 0 0 0 512095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QRPYDVIADPTVTPK MGYG000002561_02257;MGYG000001346_03128;MGYG000001313_01399;MGYG000000224_02589 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,4AK9W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrA 1.0 - 1.0 1.6.5.8 1.0 ko:K00346 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQRA,NQRA_SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002561_02257 0.25 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 - 1.0 K00346:nqrA; Na+-transporting NADH:ubiquinone oxidoreductase subunit A [EC:7.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 741108 0 0 0 0 0 0 789304 0 0 0 0 743855 0 0 0 0 569218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733502 0 0 0 0 0 0 229825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QRVALGR MGYG000003450_00520;MGYG000004022_02346;MGYG000000463_01070;MGYG000002274_02270;MGYG000003166_00269;MGYG000000084_00605;MGYG000003266_01093;MGYG000000131_01048;MGYG000003899_00682;MGYG000000036_00877;MGYG000000352_00466;MGYG000002934_00266;MGYG000003937_00574 domain d__Bacteria 1.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGC7@541000|Ruminococcaceae 0.8461538461538461 186801|Clostridia 0.8461538461538461 P 0.9230769230769231 Belongs to the ABC transporter superfamily 0.8461538461538461 - 0.5384615384615384 - 1.0 - 1.0 ko:K10112 1.0 ko02010,map02010 1.0 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1 1.0 - 1.0 - 1.0 ABC_tran,TOBE,TOBE_2 0.9230769230769231 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003450_00520 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10112:msmX, msmK, malK, sugC, ggtA, msiK; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QRVAMGR MGYG000000127_05464;MGYG000001310_01635;MGYG000000142_00551;MGYG000000251_02973;MGYG000000312_02369;MGYG000003683_01833;MGYG000000031_00294;MGYG000004271_01581;MGYG000003702_02462;MGYG000000245_00944;MGYG000000002_00989;MGYG000000216_00631;MGYG000002517_01911;MGYG000001338_00540;MGYG000000187_01370;MGYG000002298_01871;MGYG000004733_00020;MGYG000001315_00237;MGYG000002279_00971;MGYG000004296_01406;MGYG000000271_00816;MGYG000000193_03113 domain d__Bacteria 1.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XYK4@572511|Blautia 0.45454545454545453 186801|Clostridia 0.9545454545454546 P 0.9090909090909091 Belongs to the ABC transporter superfamily 0.6363636363636364 ugpC_1 0.9545454545454546 - 1.0 - 0.9545454545454546 ko:K10112 0.9545454545454546 ko02010,map02010 1.0 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 0.9545454545454546 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 0.9545454545454546 3.A.1.1 0.9545454545454546 - 1.0 - 1.0 ABC_tran,TOBE,TOBE_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000127_05464 0.045454545454545456 - - - - 0.9545454545454546 0.9545454545454546 0.9545454545454546 0.9545454545454546 ABC transporters 1.0 K10112:msmX, msmK, malK, sugC, ggtA, msiK; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] 0.9545454545454546 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSASDVGNDHR MGYG000002141_00290;MGYG000000217_02029 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,27I8W@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Glutamine synthetase type III N terminal 1.0 glnA 1.0 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002141_00290 0.5 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Glyoxylate and dicarboxylate metabolism|Nitrogen metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Biosynthesis of amino acids|Two-component system|Necroptosis|Glutamatergic synapse|GABAergic synapse 1.0 K01915:glnA, GLUL; glutamine synthetase [EC:6.3.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479791 0 0 0 0 379570 0 0 0 0 293666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSC(Carbamidomethyl)EAAVAAIQK MGYG000000196_00720;MGYG000004797_01109;MGYG000003312_00148;MGYG000000098_01819;MGYG000001378_04763;MGYG000000054_01406;MGYG000001313_02680;MGYG000002549_01301;MGYG000003351_01089;MGYG000002560_01042;MGYG000001461_03637;MGYG000002455_02688;MGYG000000105_00820;MGYG000001345_02082;MGYG000003681_01697;MGYG000002171_01456;MGYG000001780_01857;MGYG000002281_01592;MGYG000000243_02393;MGYG000000029_00263 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,2FNGC@200643|Bacteroidia,4AKIZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Belongs to the GHMP kinase family. GalK subfamily 1.0 galK 1.0 - 1.0 2.7.1.6 1.0 ko:K00849 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00554,M00632 1.0 R01092 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00720 0.05 galactokinase. - Part of the Leloir pathway for galactose metabolism.-!-The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine. alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+). 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K00849:galK; galactokinase [EC:2.7.1.6] 1.0 none 1.0 540299 602810 938684 526410 456721 579975 656205 0 0 0 574996 0 537172 470234 236814 565617 0 400666 0 614408 558287 529757 494132 726076 657340 594580 754267 425618 585647 0 877298 0 970744 623013 516409 661899 484779 616532 515913 521631 604774 686932 666934 611339 539048 0 0 0 789057 0 602396 624100 641585 589701 0 0 0 296800 374929 443421 262997 513483 582781 347063 532650 0 496900 0 493602 0 445165 508309 0 402254 529801 350146 0 292322 366592 318159 428067 478365 504798 0 0 0 375869 0 134899 0 248764 248543 0 650828 0 292183 446927 280866 351529 0 0 404090 0 191468 376016 0 287380 0 461869 0 0 301327 0 387714 0 0 206144 214481 175609 0 633024 0 0 0 461689 0 389151 0 0 319722 0 277403 0 0 0 511123 0 688035 249269 387953 0 0 0 0 372196 0 397080 148718 281831 256513 390620 372256 359763 0 290928 468031 715183 755407 270097 0 0 0 419132 0 525278 397630 360919 454929 0 757928 0 914249 0 663872 700471 576566 694772 619634 472580 411778 496957 0 521854 0 376385 536668 742671 518658 748044 519570 +(Gln->pyro-Glu)QSC(Carbamidomethyl)EAAVAAIQKK MGYG000000196_00720;MGYG000004797_01109;MGYG000000098_01819;MGYG000001378_04763;MGYG000000054_01406;MGYG000001313_02680;MGYG000002549_01301;MGYG000003351_01089;MGYG000002560_01042;MGYG000002455_02688;MGYG000000105_00820;MGYG000001345_02082;MGYG000003681_01697;MGYG000002171_01456;MGYG000001780_01857;MGYG000002281_01592;MGYG000000243_02393 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,2FNGC@200643|Bacteroidia,4AKIZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Belongs to the GHMP kinase family. GalK subfamily 1.0 galK 1.0 - 1.0 2.7.1.6 1.0 ko:K00849 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00554,M00632 1.0 R01092 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00720 0.058823529411764705 galactokinase. - Part of the Leloir pathway for galactose metabolism.-!-The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine. alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+). 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K00849:galK; galactokinase [EC:2.7.1.6] 1.0 none 1.0 1367923 2405300 2251360 0 2229641 2057067 1897407 2016482 0 2000208 0 2230614 0 1628243 1728427 2539008 2095507 1086972 1680394 0 0 0 1157211 1910946 0 1826715 0 0 2118833 2064873 0 0 2984706 1673971 0 0 1659606 2352757 1752512 1400530 1769970 0 1845139 1473392 1487180 0 0 1834736 2136337 1294154 0 1472244 1477988 1727705 1359176 713331 1601298 0 1277248 1458140 945649 1414012 1570642 0 0 1292702 1571353 1621503 0 0 1784614 0 0 0 1527838 1389623 1155268 1377008 1130552 0 1596255 1232874 1497638 1647040 0 1167350 975796 834282 0 1036146 1092893 1268387 1221406 0 1204090 0 2124404 1064184 0 924614 950227 1206495 0 2958051 1603156 1401334 0 0 381340 1153600 0 0 1186918 1340870 729844 749473 512125 0 860010 575525 739309 0 0 672930 567767 700758 0 594204 714043 464446 423935 359626 367582 0 485548 625305 0 0 925634 627019 0 734011 431498 505496 0 0 617084 428878 0 0 728275 383777 1041608 938674 1284116 0 1508306 1562240 589080 1105211 0 729624 1000517 1092421 0 878164 1135325 1161926 0 1253057 1165789 0 933636 1265920 1115048 1679826 1079150 1539535 0 1103160 512442 1281845 0 0 1055891 1485375 0 0 1467693 1222540 +(Gln->pyro-Glu)QSC(Carbamidomethyl)EAVVAAIKK MGYG000003693_01873 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,2FNGC@200643|Bacteroidia,4AKIZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Belongs to the GHMP kinase family. GalK subfamily 1.0 galK 1.0 - 1.0 2.7.1.6 1.0 ko:K00849 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00554,M00632 1.0 R01092 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_01873 1.0 galactokinase. - Part of the Leloir pathway for galactose metabolism.-!-The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine. alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+). 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K00849:galK; galactokinase [EC:2.7.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775830 0 0 0 0 1003908 0 0 0 0 698994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 768642 0 0 0 0 1006698 0 0 0 0 419936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSDC(Carbamidomethyl)NANSSISHEAVR MGYG000001313_02503;MGYG000003681_00913;MGYG000000224_00039 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_02503 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376527 0 0 0 0 652839 908814 936313 0 0 707886 0 0 0 0 0 460334 0 618937 0 0 870943 0 0 0 0 625640 0 0 401405 0 0 0 872070 0 0 0 0 640045 0 0 0 0 889050 650208 796247 0 0 589691 0 0 0 0 0 1963093 0 555660 0 0 1236801 0 0 0 0 1222895 0 0 1063320 0 0 0 629410 0 0 0 0 0 0 0 0 0 444185 409270 334964 0 0 0 0 0 0 0 0 0 0 369418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSDILAVVK MGYG000000133_00303 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,25X0R@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00303 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04078:groES, HSPE1; chaperonin GroES 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1140260 1256579 971151 1463129 482229 856898 1415617 961564 896517 1317899 1510836 758574 1840450 2090252 1039387 1209585 1121016 0 826005 0 939270 827705 0 658825 1095510 983151 1411463 0 1680043 0 731365 2090581 1643198 1482679 0 974743 1043177 646636 +(Gln->pyro-Glu)QSEFFLYSKK MGYG000001637_01978;MGYG000002202_01441;MGYG000004719_00689;MGYG000000245_00251;MGYG000000489_00414;MGYG000002517_01550 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 E 1.0 Belongs to the alpha-IPM synthase homocitrate synthase family 0.8333333333333334 - 1.0 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 iHN637.CLJU_RS03250 1.0 HMGL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_01978 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSETAAVEIKR MGYG000002494_02854 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0840@1|root,COG0840@2|Bacteria,1MU9B@1224|Proteobacteria,1RMH0@1236|Gammaproteobacteria,3WXSN@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 NT 1.0 Homologues of the ligand binding domain of Tar 1.0 tsr 1.0 GO:0001101,GO:0001932,GO:0003674,GO:0004888,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0006935,GO:0007154,GO:0007165,GO:0007172,GO:0008104,GO:0008150,GO:0009593,GO:0009605,GO:0009719,GO:0009966,GO:0009987,GO:0010033,GO:0010243,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019220,GO:0019222,GO:0019899,GO:0019900,GO:0019901,GO:0022607,GO:0023051,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031399,GO:0032101,GO:0032110,GO:0032268,GO:0032879,GO:0032991,GO:0033036,GO:0034613,GO:0034622,GO:0038023,GO:0040011,GO:0040012,GO:0042221,GO:0042325,GO:0042330,GO:0042802,GO:0042803,GO:0043113,GO:0043200,GO:0043424,GO:0043549,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0046983,GO:0048583,GO:0048870,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051174,GO:0051179,GO:0051246,GO:0051259,GO:0051260,GO:0051270,GO:0051338,GO:0051606,GO:0051641,GO:0051668,GO:0051674,GO:0051716,GO:0060089,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0070727,GO:0070887,GO:0071229,GO:0071230,GO:0071310,GO:0071417,GO:0071495,GO:0071840,GO:0071944,GO:0072657,GO:0080090,GO:0098561,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902021,GO:2000145 1.0 - 1.0 ko:K03406,ko:K05874,ko:K05875,ko:K05876,ko:K05877 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 4HB_MCP_1,HAMP,MCPsignal,TarH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02854 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03406:mcp; methyl-accepting chemotaxis protein|K05874:tsr; methyl-accepting chemotaxis protein I, serine sensor receptor|K05875:tar; methyl-accepting chemotaxis protein II, aspartate sensor receptor|K05876:trg; methyl-accepting chemotaxis protein III, ribose and galactose sensor receptor|K05877:tap; methyl-accepting chemotaxis protein IV, peptide sensor receptor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 784058 841204 821624 566241 0 1172302 884728 0 0 1182326 0 0 0 895877 0 0 944259 0 977333 0 959851 1288041 0 1182544 832547 727966 631554 0 892255 825704 0 0 848963 0 0 0 662191 614748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSEYASQLKEK MGYG000001300_02187;MGYG000003899_00641 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02187 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 402191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463614 0 0 0 589671 0 0 0 0 0 0 0 0 0 452406 0 437053 0 0 0 0 0 0 0 356044 0 0 0 0 0 373231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSFYAAFYK MGYG000000243_00718;MGYG000003351_03535;MGYG000003367_02308;MGYG000002561_01067;MGYG000002549_02853;MGYG000001661_03082;MGYG000002717_01899;MGYG000002455_00013;MGYG000000224_01788;MGYG000000196_04182;MGYG000001337_03773;MGYG000004824_01681;MGYG000004899_00369;MGYG000002171_00434;MGYG000003363_01242;MGYG000001345_00362;MGYG000000098_00764;MGYG000002478_02176;MGYG000001346_02491 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2207@1|root,COG2207@2|Bacteria,4NVK3@976|Bacteroidetes,2FRSW@200643|Bacteroidia,4AN3S@815|Bacteroidaceae 0.7368421052631579 976|Bacteroidetes 1.0 K 0.7894736842105263 transcriptional regulator (AraC 0.7368421052631579 - 1.0 - 1.0 - 0.7894736842105263 - 0.7894736842105263 - 1.0 - 1.0 - 1.0 - 1.0 - 0.7894736842105263 - 1.0 - 1.0 - 1.0 HTH_18,TPR_8 0.7894736842105263 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00718 0.05263157894736842 - - - - 0.7894736842105263 0.7894736842105263 0.7894736842105263 0.7894736842105263 - 1.0 - 0.7894736842105263 none 1.0 196111 0 218641 203372 274771 153150 213492 261173 0 0 243574 204765 0 0 0 0 281948 0 0 0 339822 248982 0 298207 276640 327760 0 0 301779 266726 431029 0 429190 210471 347235 131807 73900 369086 228055 0 392972 411418 526463 485292 483475 752346 0 0 614640 617083 0 0 0 0 456396 0 0 0 515670 435090 0 361339 210986 337641 0 0 410030 495496 263529 0 227196 516054 501694 397506 314232 469694 0 0 93887 99939 127422 247390 124500 0 0 0 260488 267046 0 0 0 0 110138 0 0 0 173139 183815 0 135448 174547 97145 0 0 261359 201590 285179 0 143035 108806 173522 188255 71436 192049 53454 0 0 0 0 0 0 62473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 69904 0 0 0 0 0 0 0 0 0 62378 0 0 72360 0 71817 0 224445 254548 230594 44548 0 0 240015 189065 0 0 0 0 89584 0 0 0 168747 0 0 255613 179146 181809 0 0 60040 180855 3058 0 72405 0 0 0 0 3447 +(Gln->pyro-Glu)QSGGHGQYGHVK MGYG000004733_01898;MGYG000000251_02148;MGYG000000249_00677;MGYG000000002_01361;MGYG000000404_01392;MGYG000002298_01791;MGYG000004735_01956;MGYG000002025_01499;MGYG000000142_02369;MGYG000002492_01806;MGYG000002772_00739;MGYG000000271_00034;MGYG000002835_01987;MGYG000000154_00745;MGYG000002202_01144;MGYG000000095_04309;MGYG000000171_00253;MGYG000004271_00377;MGYG000001338_01579;MGYG000000164_00435;MGYG000002517_01557;MGYG000000201_01853;MGYG000002966_02309;MGYG000002279_00268;MGYG000000133_01852;MGYG000000212_00731 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3XZ5X@572511|Blautia 0.38461538461538464 186801|Clostridia 1.0 J 1.0 translation elongation factor G 0.38461538461538464 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_01898 0.038461538461538464 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 683783 0 702973 1000471 913424 0 0 0 0 0 1814144 0 0 0 0 629833 0 0 0 0 1166264 0 633131 0 0 0 0 625206 0 0 0 0 0 0 0 0 0 0 603733 0 469311 782985 488259 0 0 0 0 0 693072 0 0 0 0 560593 0 0 0 0 1030028 0 576587 0 0 0 0 502286 0 0 0 0 0 0 0 0 0 0 273898 0 408077 460056 137586 0 0 0 0 0 0 0 0 0 0 702188 0 0 0 0 1214934 0 644545 0 0 0 0 598067 0 0 0 0 0 0 0 0 0 0 308631 0 323215 348506 326150 0 0 0 0 0 364722 0 0 0 0 35240 0 0 0 0 523572 0 382210 0 0 0 0 194486 0 0 0 0 0 0 0 0 0 0 48288 0 675440 771609 641087 0 0 0 0 0 258559 0 0 0 0 421362 0 0 0 0 437451 0 67265 0 0 0 0 413901 0 0 0 +(Gln->pyro-Glu)QSGGKGQYGHVK MGYG000002040_01211;MGYG000003937_01028;MGYG000003450_00444;MGYG000000084_01999;MGYG000001300_00281;MGYG000000436_01219 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.8333333333333334 186801|Clostridia 0.8333333333333334 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000002040_01211 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 715347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1033585 0 1038986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319080 0 483356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 942075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 672786 0 543727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSGGRGQYGHC(Carbamidomethyl)K MGYG000001615_01715;MGYG000002279_01931;MGYG000000171_02843;MGYG000000201_03874;MGYG000000417_00151;MGYG000004735_00885;MGYG000002966_00551;MGYG000001688_04230;MGYG000000271_03364;MGYG000000038_00759;MGYG000001367_00668;MGYG000001315_01206;MGYG000003702_00714;MGYG000000133_02992;MGYG000000262_00029;MGYG000001707_01475;MGYG000001379_00688;MGYG000000198_01164;MGYG000001310_01964;MGYG000002528_01099;MGYG000000562_01882;MGYG000000179_00921;MGYG000000216_02407;MGYG000003381_01598;MGYG000002517_00204;MGYG000000177_01045;MGYG000002298_03446;MGYG000004296_01667;MGYG000001637_00070;MGYG000003366_00387;MGYG000001338_03374;MGYG000000142_00172;MGYG000000251_00063;MGYG000000233_00808;MGYG000000200_01983;MGYG000000050_01748;MGYG000000146_01349;MGYG000000255_02008;MGYG000004891_02430;MGYG000004087_00550;MGYG000000164_01097;MGYG000004642_00845;MGYG000000212_03312;MGYG000000187_02028;MGYG000000154_02190;MGYG000002946_01538;MGYG000004285_00598;MGYG000004271_02230;MGYG000002212_00197;MGYG000000002_03595;MGYG000001617_01407;MGYG000003355_03290;MGYG000004733_01212 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.33962264150943394 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 0.9811320754716981 MGYG000001615_01715 0.018867924528301886 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 591855 124757 0 0 0 0 0 327836 362573 0 0 0 208353 0 0 0 421308 227924 0 0 0 0 0 0 0 0 0 0 0 308796 289698 0 0 0 0 225363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228079 62718 0 0 0 0 0 127261 146504 0 0 0 103480 0 0 0 115419 127153 0 0 0 0 0 0 0 0 0 0 0 319281 255713 0 0 0 0 0 0 0 187023 295674 0 0 0 0 0 205499 114739 0 0 0 356084 0 0 0 370894 177596 0 0 0 0 0 0 0 0 0 0 0 289751 141890 0 0 0 0 145002 0 0 441100 446561 0 0 0 0 0 483688 373397 0 0 0 147410 0 0 0 81849 0 0 0 0 0 0 0 0 0 0 0 0 324697 628813 0 0 0 0 343259 +(Gln->pyro-Glu)QSHQEMLDHVEGLLK MGYG000004797_00953;MGYG000002478_04065 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0172@1|root,COG0172@2|Bacteria,4NED6@976|Bacteroidetes,2FN99@200643|Bacteroidia,4AK72@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Psort location Cytoplasmic, score 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_00953 0.5 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01875:SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291057 0 0 0 0 526314 0 0 0 0 399068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 506824 0 0 0 0 423742 0 0 0 0 321052 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSIAKEDALKK MGYG000002478_04502;MGYG000004797_02455 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,2FMAU@200643|Bacteroidia,4AMPD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000002478_04502 0.5 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01868:TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSINGATN(Deamidated)PYYYAPIR MGYG000002082_00620 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900544265|m__MGYG000002082 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002082_00620 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124629 0 226725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16884039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16914493 0 17938272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSIPLANAMR MGYG000002438_00646 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG3291@1|root,COG3291@2|Bacteria,4PMYH@976|Bacteroidetes,2G0KU@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Domain of Unknown Function (DUF1080) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1080 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00646 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269708 0 0 0 0 0 0 0 0 0 0 0 0 0 653621 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSITIPAKR MGYG000002455_01438 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia,4ARQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_01438 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1922312 0 0 0 0 1579565 0 0 0 0 1183361 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSKQPLQR MGYG000002494_03339 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2376@1|root,COG2376@2|Bacteria,1MVSR@1224|Proteobacteria,1RNRQ@1236|Gammaproteobacteria,3WVUW@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Dak1 domain 1.0 dhaK 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 1.0 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 1.0 ko:K00863,ko:K05878 1.0 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 1.0 M00344 1.0 R01011,R01012,R01059 1.0 RC00002,RC00015,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 1.0 Dak1,Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03339 1.0 phosphoenolpyruvate--glycerone phosphotransferase. | triokinase. | glycerone kinase. | FAD-AMP lyase (cyclizing). triose kinase. | dihydroxyacetone kinase. | FMN cyclase. While FAD was the best substrate tested the enzyme also splits ribonucleoside diphosphate-X compounds in which X is an acyclic or cyclic monosaccharide or derivative bearing an X-OH group that is able to attack internally the proximal phosphorus with the geometry necessary to form a P=X product; either a five-atom monocyclic phosphodiester or a cis-bicyclic phosphodiester-pyranose fusion.-!-The reaction is strongly inhibited by ADP or ATP but is unaffected by the presence of the product, cFMN. dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. | ATP + D-glyceraldehyde = ADP + D-glyceraldehyde 3-phosphate + H(+). | ATP + dihydroxyacetone = ADP + dihydroxyacetone phosphate + H(+). | FAD = AMP + H(+) + riboflavin cyclic-4',5'-phosphate. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Glycerolipid metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|RIG-I-like receptor signaling pathway 1.0 K00863:DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]|K05878:dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 833798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 983343 0 691330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSLSPSTQWEWNK MGYG000001783_01400;MGYG000003693_03081 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 MGYG000001783_01400 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 535728 0 0 0 0 1723088 0 0 0 0 928714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407856 0 0 0 0 287474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSNYNFSTGDLR MGYG000001346_03588 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 2DUCV@1|root,33Q16@2|Bacteria,4PMVT@976|Bacteroidetes,2G0IH@200643|Bacteroidia,4AV8P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_03588 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1039391 410586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289649 397565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 776399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSPITNLAR MGYG000000271_03295;MGYG000000164_01128;MGYG000002517_00193;MGYG000000179_05049;MGYG000002279_01915;MGYG000004271_02223;MGYG000000198_05827;MGYG000000038_00775 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia 0.375 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_03295 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02864:RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 465599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1320148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSPNDPNSVWKK MGYG000000217_03304 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Acetatifactor|s__Acetatifactor sp900066565|m__MGYG000000217 1.0 COG1653@1|root,COG1653@2|Bacteria,1TW09@1239|Firmicutes,24BZW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 transport 1.0 - 1.0 - 1.0 - 1.0 ko:K02027,ko:K17318 1.0 ko02010,map02010 1.0 M00207,M00603 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1,3.A.1.1.29,3.A.1.1.9 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000217_03304 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K02027:ABC.MS.S; multiple sugar transport system substrate-binding protein|K17318:lplA; putative aldouronate transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359720 0 0 0 0 554721 0 0 0 0 806343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSPQVLNLPFKEGISR MGYG000000133_00308 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3XYNE@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 8.87 1.0 purH 1.0 - 1.0 2.1.2.3,3.5.4.10 1.0 ko:K00602 1.0 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 1.0 M00048 1.0 R01127,R04560 1.0 RC00026,RC00263,RC00456 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 AICARFT_IMPCHas 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00308 1.0 phosphoribosylaminoimidazolecarboxamide formyltransferase. | IMP cyclohydrolase. aminoimidazolecarboxamide ribonucleotide transformylase. | inosinicase. - (6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. | H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. 1.0 1.0 1.0 1.0 Purine metabolism|One carbon pool by folate|Metabolic pathways|Biosynthesis of secondary metabolites|Antifolate resistance 1.0 K00602:purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530771 985667 0 0 401368 0 0 492773 596988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 414939 740379 1320255 0 0 0 0 606628 +(Gln->pyro-Glu)QSPQVLSLPFKPGIK MGYG000002517_01952 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Bifunctional purine biosynthesis protein PurH 1.0 purH 1.0 - 1.0 2.1.2.3,3.5.4.10 1.0 ko:K00602 1.0 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 1.0 M00048 1.0 R01127,R04560 1.0 RC00026,RC00263,RC00456 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 AICARFT_IMPCHas 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01952 1.0 phosphoribosylaminoimidazolecarboxamide formyltransferase. | IMP cyclohydrolase. aminoimidazolecarboxamide ribonucleotide transformylase. | inosinicase. - (6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. | H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. 1.0 1.0 1.0 1.0 Purine metabolism|One carbon pool by folate|Metabolic pathways|Biosynthesis of secondary metabolites|Antifolate resistance 1.0 K00602:purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541970 0 0 0 0 0 0 0 0 1276800 0 0 0 0 1127460 0 934482 0 0 0 0 0 0 0 933709 1009510 946820 0 0 0 0 0 0 0 0 916073 1370953 0 +(Gln->pyro-Glu)QSPSVILIDTTVIANAPVR MGYG000004717_01070;MGYG000002966_00993 domain d__Bacteria 1.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,4H3R3@909932|Negativicutes 0.5 909932|Negativicutes 0.5 C 1.0 Iron-containing alcohol dehydrogenase 0.5 - 0.5 - 1.0 1.1.1.6 1.0 ko:K00005 1.0 ko00561,ko00640,ko01100,map00561,map00640,map01100 1.0 - 1.0 R01034,R10715,R10717 1.0 RC00029,RC00117,RC00670 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004717_01070 0.5 glycerol dehydrogenase. NAD-linked glycerol dehydrogenase. Also acts on 1,2-propanediol. glycerol + NAD(+) = dihydroxyacetone + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Propanoate metabolism|Metabolic pathways 1.0 K00005:gldA; glycerol dehydrogenase [EC:1.1.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35854663 0 0 17416101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14468689 0 38700444 0 0 0 0 0 0 0 0 43620611 0 0 0 0 26237042 +(Gln->pyro-Glu)QSQEEMGHAYAMADYIIKR MGYG000000013_01582;MGYG000001345_00719;MGYG000002549_02437;MGYG000000196_02859;MGYG000001378_01746 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1528@1|root,COG1528@2|Bacteria,4NGS7@976|Bacteroidetes,2FQD1@200643|Bacteroidia,4AP5J@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Iron-storage protein 1.0 ftnA 1.0 - 1.0 1.16.3.2 1.0 ko:K02217 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ferritin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_01582 0.2 bacterial non-heme ferritin. - Ferritins are intracellular iron-storage and detoxification proteins found in all kingdoms of life.-!-They are formed from two subunits that coassemble in various ratios to form a spherical protein shell.-!-Thousands of mineralized iron atoms are stored within the core of the structure.-!-The product of dioxygen reduction by the bacterial non-heme ferritin is hydrogen peroxide, which is consumed in a subsequent reaction. 4 Fe(2+) + 6 H2O + O2 = 12 H(+) + 4 iron(III) oxide-hydroxide. 1.0 1.0 1.0 1.0 - 1.0 K02217:ftnA, ftn; ferritin [EC:1.16.3.2] 1.0 none 1.0 570975 576015 0 0 0 0 0 0 0 0 610274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478554 0 0 0 0 0 0 0 0 724255 423855 517249 0 1557753 672673 0 0 0 0 0 0 0 0 1797586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 950061 0 0 0 0 0 0 0 0 1545762 973907 2206175 0 415062 0 0 0 0 0 0 0 0 0 191596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161570 0 0 0 0 0 0 0 0 0 182413 0 0 382271 474510 0 0 0 0 0 0 0 0 483012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331530 0 0 0 0 0 0 0 0 863299 396731 779191 0 12168 292860 0 0 0 0 0 0 0 0 1048501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3298447 0 0 0 0 0 0 0 0 0 8880 19274 0 +(Gln->pyro-Glu)QSQGVAIAYDSR MGYG000000133_00139;MGYG000003821_00787;MGYG000003012_01663 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 pgcA 1.0 - 1.0 5.4.2.2,5.4.2.8 1.0 ko:K01835,ko:K01840 1.0 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00114,M00549 1.0 R00959,R01057,R01818,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Alpha-amylase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000133_00139 0.3333333333333333 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). | phosphomannomutase. phosphoglucose mutase. | phosphomannose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. | alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. | alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2]|K01840:manB; phosphomannomutase [EC:5.4.2.8] 1.0 none 1.0 0 0 134009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518309 0 0 656023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 749312 0 0 0 0 381881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733560 0 0 0 0 994258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340489 0 0 0 0 0 +(Gln->pyro-Glu)QSQISGHVTSSEDGSPVIGASIK MGYG000003697_00736 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2G3FU@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_00736 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2170372 0 1101481 1737858 0 0 0 0 1559359 0 1461582 0 0 1075489 0 3346911 0 0 0 2154195 5396605 1500365 0 0 0 2300507 0 0 0 0 1584594 0 0 0 0 1680994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSSDQKELALK MGYG000000003_02214 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG5010@1|root,COG5010@2|Bacteria 1.0 2|Bacteria 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2.7.11.1 1.0 ko:K14949 1.0 ko05152,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01001 1.0 - 1.0 - 1.0 - 1.0 AAT,DUF3868,Glyco_trans_1_2,Glyco_transf_4,Glycos_transf_2,MecA_N,Methyltransf_23,OmpA,PMT_2,Pkinase,PknG_TPR,PknG_rubred,SPOR,Sulfotransfer_3,TPR_11,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8,UnbV_ASPIC,VCBS,gag-asp_proteas 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_02214 1.0 non-specific serine/threonine protein kinase. threonine-specific protein kinase. This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.-!-Formerly EC 2.7.1.37 and EC 2.7.1.70. (1) ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]. (2) ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl- [protein]. 1.0 1.0 1.0 1.0 Tuberculosis 1.0 K14949:pknG; serine/threonine-protein kinase PknG [EC:2.7.11.1] 1.0 none 1.0 0 0 0 0 0 0 606945 0 688424 0 0 0 0 0 0 0 0 0 1058031 0 899633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSSGAPGASSQIIIR MGYG000001313_01935;MGYG000004479_01491;MGYG000001783_00567 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG3188@1|root,COG1629@2|Bacteria,COG3188@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4ANM7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 NPU 1.0 Psort location OuterMembrane, score 9.49 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_01935 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 698371 0 0 0 0 0 0 0 0 0 0 1679901 0 0 0 0 1542291 0 0 0 0 1450441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596648 0 0 0 0 0 0 0 0 0 1168533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSSGAPGASSQIVIR MGYG000003363_02129;MGYG000003681_00347 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1629@1|root,COG3188@1|root,COG1629@2|Bacteria,COG3188@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4ANM7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 NPU 1.0 Psort location OuterMembrane, score 9.49 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003363_02129 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459958 0 0 0 0 0 0 724186 708628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572494 781737 0 0 0 0 0 0 0 0 0 0 492966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSTHAQEC(Carbamidomethyl)VSK MGYG000002517_02716 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia 1.0 186801|Clostridia 1.0 NT 1.0 methyl-accepting chemotaxis protein 1.0 - 1.0 - 1.0 - 1.0 ko:K03406 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 HAMP,MCPsignal,dCache_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02716 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03406:mcp; methyl-accepting chemotaxis protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656477 523401 0 0 0 0 0 0 0 0 0 0 553097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168574 0 0 0 0 0 0 0 0 0 0 393336 0 +(Gln->pyro-Glu)QSVAQYVAQVAK MGYG000000233_01317;MGYG000000205_00610;MGYG000000274_02582;MGYG000000251_01122;MGYG000000194_00522;MGYG000000278_03744;MGYG000004735_00873;MGYG000000255_00470;MGYG000002445_00993 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,21ZJJ@1506553|Lachnoclostridium 0.7777777777777778 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_01317 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 182833 96442 0 0 0 0 0 0 0 324679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 148391 0 0 0 0 0 0 0 216330 446231 0 0 0 0 0 0 0 540284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 233693 0 0 0 0 144408 0 0 131787 129808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288353 0 0 0 0 79797 +(Gln->pyro-Glu)QSVDDIHK MGYG000000074_01707;MGYG000002082_02076 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,22U6H@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Fumarate reductase flavoprotein C-term 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01707 0.5 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 883647 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSVDDIHKK MGYG000002203_00448;MGYG000001546_01596;MGYG000004006_00370;MGYG000000003_02554;MGYG000001302.1_00465;MGYG000001663_00888;MGYG000001420_00223;MGYG000000074_01707;MGYG000001415_01060;MGYG000002082_02076 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,22U6H@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Fumarate reductase flavoprotein C-term 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002203_00448 0.1 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 292269 287909 0 0 0 0 0 277766 0 0 0 0 0 0 0 0 462045 459696 0 0 0 0 0 0 0 0 0 644999 324233 0 264594 0 341036 0 0 311115 0 0 244482 328045 0 0 0 0 0 289731 0 0 0 0 0 0 0 0 315807 362288 0 0 0 0 0 0 0 0 0 185721 133997 0 129965 0 323690 0 0 298740 0 0 456996 294064 0 0 0 0 0 289954 0 0 0 0 0 0 0 0 183675 443246 0 0 0 0 0 0 0 0 0 416658 238855 0 256885 0 337604 0 0 238453 0 0 349885 240968 0 0 0 0 0 394690 0 0 0 0 0 0 0 0 666503 310130 0 0 0 0 0 0 0 0 0 340972 290964 0 395033 0 288020 0 0 332679 0 0 610404 890683 0 0 0 0 0 713317 0 0 0 0 0 0 0 0 949755 983219 0 0 0 0 0 0 0 0 0 838335 534389 0 642521 0 1240248 0 0 725731 +(Gln->pyro-Glu)QSVDEQFYSYIRPQETGNKTDIR MGYG000000243_02704 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,2FM0P@200643|Bacteroidia,4AKD1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG3250 Beta-galactosidase beta-glucuronidase 1.0 lacZ 1.0 - 1.0 3.2.1.23 1.0 ko:K01190 1.0 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 1.0 - 1.0 R01105,R01678,R03355,R04783,R06114 1.0 RC00049,RC00452 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N 1.0 3.2.1.23 1.0 GH2 1.0 GH2 1.0 GH2 1.0 MGYG000000243_02704 1.0 beta-galactosidase. lactase. Some enzymes in this group hydrolyze alpha-L-arabinosides; some animal enzymes also hydrolyze beta-D-fucosides and beta-D-glucosides (cf. EC 3.2.1.108). Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D- galactosides. 1.0 1.0 1.0 1.0 Galactose metabolism|Other glycan degradation|Sphingolipid metabolism|Metabolic pathways 1.0 K01190:lacZ; beta-galactosidase [EC:3.2.1.23] 1.0 none 1.0 0 0 525074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318352 0 0 0 0 518450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSVDQPVQTGYK MGYG000002323_04217;MGYG000000093_05346;MGYG000002366_00008;MGYG000002515_03905;MGYG000002385_03599;MGYG000002494_02406;MGYG000002506_03404 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,3XP3D@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 iSbBS512_1146.SbBS512_E4187 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000002323_04217 0.14285714285714285 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 404243 0 0 0 378067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292054 0 361351 0 0 0 0 0 287401 0 0 418844 0 0 0 0 0 0 0 1385498 0 1209975 1666341 1240227 0 960034 1193883 0 0 0 0 0 0 1447215 0 1516136 0 0 2053409 0 1411926 0 0 0 0 2524270 2023014 0 0 1072935 0 0 0 0 840428 0 0 0 0 410281 968677 445532 0 321588 383388 0 0 0 0 0 0 388516 0 0 0 0 909666 0 703900 0 0 0 0 0 516270 0 0 415189 0 0 0 0 326757 0 0 0 0 270071 343278 0 0 0 0 0 0 0 0 0 0 308653 0 0 0 0 544334 0 524322 0 0 0 0 981771 0 0 0 478734 0 0 0 0 581100 0 0 0 0 0 291202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSVIGIGEALFDVLPEGK MGYG000003697_02156 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0524@1|root,COG0524@2|Bacteria,4NGFK@976|Bacteroidetes,2FN72@200643|Bacteroidia,22WT2@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 pfkB family 1.0 ydjH_1 1.0 - 1.0 2.7.1.4 1.0 ko:K00847 1.0 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 1.0 - 1.0 R00760,R00867,R03920 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_02156 1.0 fructokinase. D-fructokinase. - ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K00847:E2.7.1.4, scrK; fructokinase [EC:2.7.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2093976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3467226 0 0 3452588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7996399 0 3852263 0 0 0 0 0 0 0 0 1597500 0 0 0 0 3154733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4042909 0 0 0 0 0 +(Gln->pyro-Glu)QSVLNVIDGK MGYG000003279_01900 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900541585|m__MGYG000003279 1.0 COG5010@1|root,COG5010@2|Bacteria 1.0 2|Bacteria 1.0 - 1.0 - 1.0 - 1.0 - 1.0 2.7.11.1 1.0 ko:K14949 1.0 ko05152,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01001 1.0 - 1.0 - 1.0 - 1.0 AAT,DUF3868,Glyco_trans_1_2,Glyco_transf_4,Glycos_transf_2,MecA_N,Methyltransf_23,OmpA,PMT_2,Pkinase,PknG_TPR,PknG_rubred,SPOR,Sulfotransfer_3,TPR_11,TPR_16,TPR_19,TPR_2,TPR_7,TPR_8,UnbV_ASPIC,VCBS,gag-asp_proteas 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003279_01900 1.0 non-specific serine/threonine protein kinase. threonine-specific protein kinase. This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.-!-Formerly EC 2.7.1.37 and EC 2.7.1.70. (1) ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]. (2) ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl- [protein]. 1.0 1.0 1.0 1.0 Tuberculosis 1.0 K14949:pknG; serine/threonine-protein kinase PknG [EC:2.7.11.1] 1.0 none 1.0 639293 0 0 0 0 0 680624 0 0 0 0 0 0 0 0 0 0 0 0 817247 0 0 0 0 528703 615738 0 0 591546 0 0 0 0 0 0 0 572023 0 0 0 0 0 0 0 70595 0 0 0 0 0 0 0 0 0 0 0 0 72584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 58111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QSYDETTNATFYSPMR MGYG000001346_03589 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_03589 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 540840 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1109337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTAAYGHFGR MGYG000001688_00425;MGYG000002946_01647;MGYG000000146_01355;MGYG000001199_03286;MGYG000002312_03155;MGYG000002772_00452;MGYG000001141_02243;MGYG000004691_01096;MGYG000003074_01494;MGYG000000143_02413;MGYG000002393_02449;MGYG000001577_00680;MGYG000000142_00387;MGYG000002286_02226;MGYG000000087_01173;MGYG000003819_01446;MGYG000001531_00352;MGYG000003063_01146;MGYG000002989_01957;MGYG000000200_02586;MGYG000000323_01801;MGYG000001496_01620;MGYG000000164_01248;MGYG000002212_00029;MGYG000000206_02668;MGYG000000268_02165;MGYG000002492_00420;MGYG000000202_00319;MGYG000001683_00544;MGYG000002517_00444;MGYG000000252_02776;MGYG000002298_01200;MGYG000000198_05052;MGYG000000212_03221;MGYG000000242_02254;MGYG000004519_00378;MGYG000000133_01435;MGYG000000806_00731;MGYG000000127_01128 domain d__Bacteria 1.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3XZ7D@572511|Blautia 0.2564102564102564 186801|Clostridia 0.9487179487179487 H 1.0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme 1.0 metK 1.0 - 0.9743589743589743 2.5.1.6 0.9743589743589743 ko:K00789 0.9743589743589743 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 0.9743589743589743 M00034,M00035,M00368,M00609 0.9743589743589743 R00177,R04771 0.9743589743589743 RC00021,RC01211 0.9743589743589743 ko00000,ko00001,ko00002,ko01000 0.9743589743589743 - 1.0 - 1.0 - 1.0 S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N,YgbB 0.9487179487179487 - 1.0 - 1.0 - 1.0 - 0.8974358974358975 MGYG000001688_00425 0.02564102564102564 methionine adenosyltransferase. S-adenosylmethionine synthetase. Formerly EC 2.4.2.13. ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L- methionine. 0.9743589743589743 0.9743589743589743 0.9743589743589743 0.9743589743589743 Cysteine and methionine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 0.9743589743589743 K00789:metK, MAT; S-adenosylmethionine synthetase [EC:2.5.1.6] 0.9743589743589743 none 1.0 1453457 1353453 752398 0 0 1047345 703806 1104001 0 0 1142603 0 1491210 1054359 0 1737729 0 476525 1058670 0 1420990 1377791 849138 945321 0 1095575 1019747 1049066 1555050 0 642750 0 844347 0 1459707 1509784 1145968 771753 203055 376444 0 0 0 0 235142 522473 0 0 747291 0 0 526716 0 0 0 0 0 0 0 0 365131 301777 0 475066 801845 0 248499 0 1859437 0 0 0 0 469137 0 0 0 1570749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356802 0 0 0 662671 0 0 0 0 174514 662612 0 0 0 0 0 0 0 513383 462941 1244520 538943 0 0 0 366058 414920 851509 0 0 161614 0 644340 1021847 0 345993 0 0 560481 0 743787 138569 0 0 0 963298 1454529 0 628575 0 549748 0 182152 0 927381 927360 825649 0 813421 741647 0 0 0 697573 0 1200762 0 0 1867724 0 1192427 2789965 0 3307338 0 483012 1913100 0 1728998 2844222 939507 2500301 0 1692705 2436106 954286 0 0 1381845 0 4461800 0 1783689 2281712 2013089 3194802 +(Gln->pyro-Glu)QTAEGALNEAHSILQR MGYG000004271_01770;MGYG000000271_01499;MGYG000000404_00502;MGYG000002492_02952 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.5 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01770 0.25 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 4077745 3633413 2468114 4682823 3517319 4064203 4753604 4921824 5868830 5923190 8835161 8601868 5622799 6342543 4831510 0 5627111 0 3933311 2186819 3483643 2917558 0 3928206 5223668 4476024 4149698 0 4884483 9905993 3298842 3263883 2295530 6185491 4437723 3760505 5447976 2072458 222645 131659 221201 0 109038 0 267681 0 0 0 362139 604674 0 0 0 0 277683 0 225524 0 0 0 0 0 0 0 0 0 0 342513 257800 0 224467 228535 0 0 154358 0 0 215045 0 0 0 0 0 0 0 0 0 0 0 0 388445 0 0 0 0 229022 0 394162 0 0 0 0 0 0 193543 0 0 435884 0 0 0 0 0 0 296869 336755 273171 0 0 0 330929 0 0 338251 0 541284 0 0 156097 0 307261 0 0 411160 0 0 0 0 0 0 0 0 0 0 553370 367129 950763 0 622611 0 0 290109 0 348729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277258 0 0 0 0 0 0 0 0 0 338272 543274 0 0 0 0 0 218036 +(Gln->pyro-Glu)QTAEGSLNEINNNLQR MGYG000002494_03500 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,3X1YU@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 fliC 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03500 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1044904 0 0 1959733 1286758 1340174 956996 1305568 0 0 0 0 0 0 1229537 0 1544127 0 1055001 1485945 0 1830383 0 0 0 0 1112052 1403463 0 0 1246759 0 0 0 0 397367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTAENAYTEHVEK MGYG000000243_02459 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 2EZ6G@1|root,33SCG@2|Bacteria,4P1BR@976|Bacteroidetes,2FN2M@200643|Bacteroidia,4AMWX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG27649 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4488 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02459 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 1723240 0 943973 0 0 0 0 0 0 0 1082440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1764100 0 0 0 0 1506161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575758 0 584401 0 0 0 0 0 0 0 836623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTAFSQYDRPQAR MGYG000002323_02346;MGYG000000093_03243;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206;MGYG000002534_02768;MGYG000001692_01757 order d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.8571428571428571 1236|Gammaproteobacteria 0.8571428571428571 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.8571428571428571 adhE 0.8571428571428571 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 0.8571428571428571 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 0.8571428571428571 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_02346 0.14285714285714285 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 276628 921121 1497609 1042498 1776764 1953759 253547 0 1149548 1690560 0 1306543 0 2313539 0 0 314164 0 1730437 193772 474941 2013738 0 2030864 1722523 1880538 1332931 0 1261470 1482350 0 1431159 297079 195597 1407854 1098463 580242 1190505 9928074 12840505 14815997 10731068 12174075 19189037 12653291 0 11725144 14608207 0 7867618 0 11840692 0 0 15441776 0 15812364 10205335 12282158 20516371 0 17465000 13562155 11674105 8977728 0 19037396 15937676 0 8261650 17150117 10946793 8243315 8723448 9793252 11269266 0 668791 512272 435045 480522 2536191 658668 0 0 522088 0 391230 0 0 0 0 431581 0 505187 0 0 2226623 0 1932111 549183 354224 518795 0 573326 170316 0 966628 1162164 1405433 646433 360671 270190 781697 1775812 2332698 2843646 2279188 2621812 2444674 1727260 0 2212537 3271802 0 2234605 0 2403563 0 0 2708456 0 2934075 604875 600528 2239283 0 2327502 2387387 806377 2641106 0 3114203 2424021 0 2602531 2975989 1779333 2724055 2236737 2006647 3304270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222722 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTAITEKFPNR MGYG000002438_02210 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0089@1|root,COG0089@2|Bacteria,4NS7H@976|Bacteroidetes,2FT3A@200643|Bacteroidia,22YD1@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome 1.0 rplW 1.0 - 1.0 - 1.0 ko:K02892 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02210 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02892:RP-L23, MRPL23, rplW; large subunit ribosomal protein L23 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 945355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1216732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTANSDVVVITSGIPR MGYG000002281_00044;MGYG000001337_04178;MGYG000000074_00796;MGYG000002549_00073;MGYG000000236_02903;MGYG000000098_01921;MGYG000001345_01394;MGYG000000196_04123;MGYG000001302.1_02054;MGYG000003922_03477;MGYG000003546_00282;MGYG000001378_03171 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,2FM7E@200643|Bacteroidia,4ANBW@815|Bacteroidaceae 0.8333333333333334 976|Bacteroidetes 1.0 C 1.0 Catalyzes the reversible oxidation of malate to oxaloacetate 1.0 mdh 1.0 - 1.0 1.1.1.37 1.0 ko:K00024 1.0 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 1.0 R00342,R07136 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ldh_1_C,Ldh_1_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_00044 0.08333333333333333 malate dehydrogenase. malic dehydrogenase. Also oxidizes some other 2-hydroxydicarboxylic acids. (S)-malate + NAD(+) = H(+) + NADH + oxaloacetate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Cysteine and methionine metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00024:mdh; malate dehydrogenase [EC:1.1.1.37] 1.0 none 1.0 0 0 0 0 0 447577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255085 0 188473 0 0 0 181960 479612 0 0 0 0 0 0 0 0 0 0 0 0 510449 0 0 0 0 262091 0 293658 0 0 0 325294 0 0 0 0 0 0 272692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 773883 0 0 0 1059933 784888 0 0 0 0 0 0 0 0 0 0 0 0 1643630 0 0 225984 0 815874 0 1173017 0 0 0 1371177 0 0 0 0 0 0 976092 0 +(Gln->pyro-Glu)QTAPNAYTEHVEK MGYG000002478_01733;MGYG000001787_02387;MGYG000004797_01424 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2EZ6G@1|root,33SCG@2|Bacteria,4P1BR@976|Bacteroidetes,2FN2M@200643|Bacteroidia,4AMWX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG27649 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4488 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01733 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 334653 0 757745 758485 823888 520719 0 0 0 367573 0 690177 1457852 0 0 1262763 0 741523 0 714571 0 608197 556907 311622 0 576062 0 563905 590095 275839 0 0 627369 0 0 604266 595271 417327 868246 0 806335 847396 1109385 626202 0 546175 0 895873 0 659010 1327721 0 0 1379050 0 0 0 783880 0 476845 334933 256325 0 777887 0 234899 643159 616397 0 0 654842 0 0 642169 606536 704874 174929 0 523509 0 527591 0 0 0 0 0 0 339363 668783 0 0 677543 0 549103 0 265193 0 0 352456 324697 0 0 0 473575 166995 295200 0 0 0 0 0 0 337106 452764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521988 0 449288 502753 992894 710862 0 463413 0 483689 0 536111 1651943 0 0 1005241 0 1493933 0 543702 0 518454 1415651 576077 0 591987 0 1210378 688959 702879 0 0 192444 0 0 472985 750141 542479 +(Gln->pyro-Glu)QTDLVEAMAK MGYG000002477_02889;MGYG000002534_02792;MGYG000002323_02376;MGYG000000093_03212;MGYG000002494_03237;MGYG000003372_04352;MGYG000002506_00505;MGYG000002515_01682;MGYG000002366_02168 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2877@1|root,COG2877@2|Bacteria,1MV91@1224|Proteobacteria,1RMGQ@1236|Gammaproteobacteria,400VK@613|Serratia 0.8888888888888888 1236|Gammaproteobacteria 1.0 M 1.0 Belongs to the KdsA family 1.0 kdsA 1.0 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0046364,GO:0046394,GO:0046400,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 0.8888888888888888 2.5.1.55 1.0 ko:K01627 1.0 ko00540,ko01100,map00540,map01100 1.0 M00063 1.0 R03254 1.0 RC00435 1.0 ko00000,ko00001,ko00002,ko01000,ko01005 1.0 - 1.0 - 1.0 - 1.0 DAHP_synth_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002477_02889 0.1111111111111111 3-deoxy-8-phosphooctulonate synthase. phospho-2-keto-3-deoxyoctonate aldolase. Formerly EC 4.1.2.16. D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-alpha-D- manno-2-octulosonate-8-phosphate + phosphate. 1.0 1.0 1.0 1.0 Lipopolysaccharide biosynthesis|Metabolic pathways 1.0 K01627:kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55] 1.0 none 1.0 0 115588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247887 321223 0 0 504149 0 0 0 354437 0 0 0 261410 0 0 418673 0 385129 0 0 526369 0 480042 0 0 0 0 694166 0 0 0 329350 0 0 0 0 366919 0 0 0 0 0 0 0 0 0 188120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260020 0 169714 0 0 331636 0 332666 0 0 0 0 95938 0 0 0 181059 0 0 0 0 99401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTENC(Carbamidomethyl)NSNSSISHEAVR MGYG000001346_01069 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_01069 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1138817 420515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391714 1170427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1360175 707409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413950 664843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2663806 472667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTEQTTEAAVVEEGGGLHK MGYG000004797_01477 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01477 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488386 0 0 0 0 300976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1671478 0 0 0 0 2644938 0 0 0 0 1656184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 910212 0 0 0 0 687983 0 0 0 0 900240 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTESHAVK MGYG000002506_03516;MGYG000002494_01479;MGYG000002502_03943;MGYG000002500_04623;MGYG000002515_03540 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2820@1|root,COG2820@2|Bacteria,1P0EC@1224|Proteobacteria,1RN3N@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 udp 1.0 GO:0003674,GO:0003824,GO:0004850,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006218,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009119,GO:0009164,GO:0009987,GO:0016043,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0022607,GO:0030955,GO:0031420,GO:0033554,GO:0034214,GO:0034641,GO:0034655,GO:0034656,GO:0042454,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046108,GO:0046131,GO:0046133,GO:0046135,GO:0046483,GO:0046700,GO:0046872,GO:0050896,GO:0051259,GO:0051716,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 1.0 2.4.2.3 1.0 ko:K00757 1.0 ko00240,ko00983,ko01100,map00240,map00983,map01100 1.0 - 1.0 R01876,R02484,R08229 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_2630,iB21_1397.B21_03667,iECABU_c1320.ECABU_c43290,iECBD_1354.ECBD_4198,iECB_1328.ECB_03718,iECD_1391.ECD_03718,iECNA114_1301.ECNA114_4136,iECOK1_1307.ECOK1_4296,iECP_1309.ECP_4040,iECS88_1305.ECS88_4275,iECSF_1327.ECSF_3683,iEcSMS35_1347.EcSMS35_4208,iLF82_1304.LF82_2357,iNRG857_1313.NRG857_19105,iUMN146_1321.UM146_19385,iUMNK88_1353.UMNK88_4655 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_03516 0.2 uridine phosphorylase. UrdPase. The enzyme participates the the pathways of pyrimidine ribonucleosides degradation and salvage.-!-The mammalian enzyme also accepts 2'-deoxyuridine.-!-Formerly EC 2.4.2.23. phosphate + uridine = alpha-D-ribose 1-phosphate + uracil. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Drug metabolism - other enzymes|Metabolic pathways 1.0 K00757:udp, UPP; uridine phosphorylase [EC:2.4.2.3] 1.0 none 1.0 182491 225463 0 307727 0 178553 203146 341486 279866 455102 0 264241 0 224853 458896 57809 0 0 255908 0 0 455540 0 0 424883 207982 198629 0 388480 245218 0 170795 0 440888 160014 183386 276219 259581 899625 704816 582841 1107909 150112 1408665 1168494 994413 663255 1441901 0 944016 0 1026116 646125 0 1274091 0 1085003 0 0 1078632 0 1024843 1052217 937639 920224 0 1009691 940946 0 792889 113704 821764 661289 647089 424121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1322958 1265780 1371289 1747474 968440 1059831 1813078 1319490 1132758 1243170 0 1423796 0 1153014 510219 683347 1396731 0 944222 0 0 1123000 0 1046277 1273934 1530028 1459213 0 987465 1592384 0 1103800 962660 1404127 1275185 542070 934285 859986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89434 0 0 0 0 0 186971 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTETTLVVN(Deamidated)QSANKPYIR MGYG000000074_00675 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1409@1|root,COG1409@2|Bacteria,4PNR4@976|Bacteroidetes,2FZJW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Putative binding domain, N-terminal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BACON 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00675 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTETTLVVNQSANKPYIR MGYG000000074_00675 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1409@1|root,COG1409@2|Bacteria,4PNR4@976|Bacteroidetes,2FZJW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Putative binding domain, N-terminal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BACON 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00675 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 124003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 646927 0 0 0 387867 0 0 0 0 0 658966 333626 1004926 0 948423 1479265 1000113 1216793 1291805 814152 1201135 1285649 0 0 1109965 0 1111616 798626 1180402 0 1778100 1640540 0 878411 0 886588 1075895 1149158 1018395 0 1188585 1879418 824858 773859 821676 0 1024012 1171975 1346122 1420459 +(Gln->pyro-Glu)QTFAEKPAEFDPR MGYG000000243_02506 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02506 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 3292926 4140964 7654486 3819904 6058801 4177543 4086046 3400504 3292070 2875542 3381627 3331996 7150531 3868021 3622899 6827301 3649071 5211362 2845189 2895106 3385625 3261830 5037379 4646125 3059752 3445927 3954859 5754355 3403383 4150509 5362080 4125456 7818448 3205362 4299819 4128568 3049339 7388035 2827709 2710249 3270030 3075631 4607174 2924935 2583040 3325924 2913587 2830304 3533799 2638865 7143541 2693499 2654538 5904323 2375026 3441163 2785684 2673509 2301876 3058390 4536729 2161453 2729509 2753044 3328846 3938523 2564221 3378157 2767025 3337795 2997120 2381245 3293121 3344310 2387715 2585936 1644867 2276128 3240539 1685071 4168983 2748024 2350517 1340090 3095320 1431577 1998014 2257044 3548667 2538629 1686268 3169907 1932304 5397472 1531589 1762323 1658969 1849112 4647636 3073194 1447251 2008794 1623850 5042620 2833796 1496685 2527628 1616156 1790731 965340 1900131 2882671 1899880 2414871 426906 627743 471254 537414 356555 630145 633461 581288 649567 774121 524767 768607 748825 366891 642579 621491 449921 0 406050 521926 632015 550700 0 474973 625110 354973 585653 210796 534281 479562 617148 583158 446675 413579 713446 629196 610898 682822 1911703 1637919 2189760 3097539 3711194 2492701 2984287 2785946 2853191 1153033 1921221 2741315 4785560 1886296 2250791 3114721 2226234 5530598 2568300 3012300 1742789 2405374 5622727 2179456 2912931 2578678 2258011 5508165 2728212 2726653 2623006 2200489 1899897 3183201 3331998 2526733 3221059 2727425 +(Gln->pyro-Glu)QTFAEKPAEFDPRK MGYG000000243_02506 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02506 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTFDKISAPEK MGYG000002528_00223 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,267YK@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01989 1.0 - 1.0 M00247 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 - 1.0 - 1.0 - 1.0 ABC_sub_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00223 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01989:K01989; putative tryptophan/tyrosine transport system substrate-binding protein 1.0 none 1.0 0 598937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427550 0 251233 0 0 0 0 745657 0 0 435760 0 0 0 0 0 0 0 1100999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 473065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1181730 0 0 0 455491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1033370 0 388353 0 0 0 0 1171296 0 0 1188313 0 0 0 0 0 0 0 919131 0 0 0 726286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 904792 0 0 1013154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTFKELQDIC(Carbamidomethyl)KK MGYG000002528_02666;MGYG000001615_04302 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 0.5 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 0.5 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02666 0.5 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2067862 0 0 0 478158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 879525 0 460282 0 0 0 0 0 0 0 1501830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTFKELQDIVKK MGYG000000404_01796 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA11774|s__UBA11774 sp003507655|m__MGYG000000404 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,27IK9@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000404_01796 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTGASDGSR MGYG000004797_02947;MGYG000000243_00135;MGYG000002478_02940 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_02947 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 492608 0 0 0 0 0 0 0 0 0 636476 0 388832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809662 0 767585 0 0 0 0 956701 0 0 0 0 0 0 0 0 0 0 0 0 851653 0 372014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155046 0 0 0 0 0 0 0 223778 0 0 0 0 0 0 0 0 0 423253 0 130403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227801 0 155101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87832 0 0 0 0 0 0 0 0 0 188835 0 73748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107376 0 0 0 0 0 0 61509 +(Gln->pyro-Glu)QTGFAMLATSSVQEVMDLAGVAHLVSLK MGYG000001546_00078 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes provencensis|m__MGYG000001546 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,22U5S@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001546_00078 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9935157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1591460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTGHMAAQVLK MGYG000000179_03811 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,267YK@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01989 1.0 - 1.0 M00247 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 - 1.0 - 1.0 - 1.0 ABC_sub_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03811 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01989:K01989; putative tryptophan/tyrosine transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1696102 0 0 0 0 0 0 0 0 0 371238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1711140 0 0 0 0 0 0 0 0 0 1625467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5762364 0 0 0 0 0 0 0 0 0 4215669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2044382 0 0 0 0 0 0 0 0 0 1216804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146864 0 0 0 0 0 0 0 0 0 1250501 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTGRPHGFLR MGYG000002323_00399;MGYG000002506_02948 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,3ZMD1@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site 1.0 rpsN 1.0 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02954 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S14 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_00399 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02954:RP-S14, MRPS14, rpsN; small subunit ribosomal protein S14 1.0 none 1.0 0 0 0 0 0 468418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 484626 0 468545 0 0 0 0 0 0 0 0 0 399648 0 138156 0 0 0 0 0 0 0 334880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366899 0 314546 0 0 0 0 0 0 0 0 0 223485 0 223465 0 0 0 0 0 0 0 988391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 646164 0 675099 0 0 0 0 0 0 0 0 0 569572 0 457753 0 0 0 0 0 0 0 374013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389375 0 317753 0 0 0 0 0 0 0 0 0 902002 0 432145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTGRPHGYVGK MGYG000002494_02456;MGYG000002535_04674;MGYG000002477_00174;MGYG000002534_00405 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0199@1|root,COG0199@2|Bacteria,1MZDT@1224|Proteobacteria,1S62N@1236|Gammaproteobacteria,3ZMD1@590|Salmonella 0.5 1236|Gammaproteobacteria 1.0 J 1.0 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site 1.0 rpsN 1.0 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02954 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S14 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02456 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02954:RP-S14, MRPS14, rpsN; small subunit ribosomal protein S14 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1864019 1534651 0 0 3249972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3111517 0 2289495 0 0 0 0 2093254 0 0 0 1989265 0 0 0 0 1365332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTGTVFNDHFSQAK MGYG000000242_00891 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,21Z0Q@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 K 1.0 PFAM regulatory protein GntR HTH 1.0 - 1.0 - 1.0 - 1.0 ko:K00375 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2,GntR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000242_00891 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K00375:K00375; GntR family transcriptional regulator / MocR family aminotransferase 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1673641 0 0 0 0 1581094 0 0 0 0 1708977 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTGTVFNDHFSQAR MGYG000000198_03565 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,21YYA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein-like domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_03565 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 896305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTGTVFNNHFAQAQAASDIAVK MGYG000000233_02993 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,21YYA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein-like domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02993 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2129513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTHTVSGTVIDKDANEPLIGANVLIK MGYG000002478_01405;MGYG000004797_04333 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKS4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01405 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 402377 0 409025 0 0 0 0 0 0 0 294173 0 0 0 0 0 0 0 0 341576 0 0 0 0 0 200511 0 0 0 0 0 0 372009 0 0 0 252023 304907 585003 0 599691 0 0 0 0 0 0 0 776226 0 0 0 0 0 0 0 0 663763 0 0 0 0 0 662530 0 0 0 0 0 0 499785 0 0 0 638675 568864 512942 0 629891 0 0 0 0 0 0 0 258115 0 0 0 0 0 0 0 0 570686 0 0 0 0 0 573098 0 0 0 0 0 0 563343 0 0 0 532015 560589 231841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268737 0 410097 0 0 0 0 0 0 0 286652 0 0 0 0 0 0 0 0 317764 0 0 0 0 0 233166 0 0 0 0 0 0 303601 0 0 0 267424 416421 +(Gln->pyro-Glu)QTIDFHYGK MGYG000000013_03819;MGYG000002438_03404;MGYG000000196_02028;MGYG000001461_02234 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,2FNA0@200643|Bacteroidia,4AM34@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 C 1.0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems 1.0 sodB 1.0 - 1.0 1.15.1.1 1.0 ko:K04564 1.0 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Sod_Fe_C,Sod_Fe_N 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_03819 0.25 superoxide dismutase. - - 2 H(+) + 2 superoxide = H2O2 + O2. 1.0 1.0 1.0 1.0 MAPK signaling pathway - fly|FoxO signaling pathway|Peroxisome|Longevity regulating pathway|Longevity regulating pathway - worm|Longevity regulating pathway - multiple species|Huntington disease 1.0 K04564:SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4335637 0 0 0 0 0 0 0 0 5487997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4916350 0 0 0 0 0 0 0 0 4483318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6176147 0 0 0 0 0 0 0 0 8254033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6375286 0 0 0 0 0 0 0 0 4296934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5142237 0 0 0 0 0 0 0 0 6468000 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTIIQGQGEHHLNILR MGYG000000074_00169 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,22UNU@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Elongation factor G, domain IV 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00169 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 378765 0 0 0 0 0 0 0 0 0 0 0 0 865794 0 0 0 807724 0 0 0 0 0 0 0 0 0 875532 0 0 0 0 0 0 758016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 896254 0 0 0 977757 0 0 0 0 0 0 0 0 0 466773 0 0 0 0 0 0 365371 0 0 0 251355 0 0 0 0 0 0 0 0 0 0 0 0 428277 0 0 0 681226 0 0 0 0 0 0 0 0 0 501234 0 0 0 0 0 0 633381 0 0 0 226030 0 0 0 0 0 0 0 0 0 0 0 0 396810 0 0 0 506403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375394 0 0 0 971204 0 0 0 0 0 0 0 0 0 0 0 0 1125086 0 0 0 1825906 0 0 0 0 0 0 0 0 0 1624134 0 0 0 0 0 0 1069578 0 0 +(Gln->pyro-Glu)QTIVGINK MGYG000000354_01445 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-485|s__CAG-485 sp001701295|m__MGYG000000354 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,22WFX@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000354_01445 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1469753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTIVHGQGEFHLR MGYG000001346_00804;MGYG000001780_04716;MGYG000000196_03773;MGYG000000243_00833;MGYG000001661_00370;MGYG000001313_03098;MGYG000001337_00442;MGYG000003363_00202;MGYG000002455_01659;MGYG000004797_02873;MGYG000004876_01617;MGYG000002171_00598;MGYG000000236_01356;MGYG000004748_03453;MGYG000002478_00020;MGYG000003922_00128 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,4AMQX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Psort location Cytoplasmic, score 9.26 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_00804 0.0625 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 1484940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1195706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1081710 0 0 0 0 0 0 0 0 0 0 0 0 0 1280726 0 0 0 0 1207850 0 0 0 0 884656 0 0 0 0 0 0 0 0 0 0 639319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 412606 0 0 0 0 0 0 313591 0 0 0 0 0 0 0 0 0 0 0 0 0 1145532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1085281 0 0 0 0 1502468 0 0 888539 0 0 0 1075478 0 0 0 +(Gln->pyro-Glu)QTIVQGQGEHHLNILK MGYG000000170_00137 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900240235|m__MGYG000000170 1.0 COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,22UNU@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Elongation factor G, domain IV 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000170_00137 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTIVSGQGEFHLR MGYG000002438_00770;MGYG000001489_00758;MGYG000003521_01095 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,22VW0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 elongation factor G 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00770 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521777 0 399090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1063115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1680369 0 1177011 0 0 0 0 0 0 +(Gln->pyro-Glu)QTLDLGN(Deamidated)GSALTTNQK MGYG000003279_01169;MGYG000000003_00249 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG3047@1|root,COG3047@2|Bacteria,4NP9X@976|Bacteroidetes,2FMHB@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 COG NOG27406 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OMP_b-brl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003279_01169 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 769669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTLDLGNGSALTTNQK MGYG000003279_01169;MGYG000000003_00249 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG3047@1|root,COG3047@2|Bacteria,4NP9X@976|Bacteroidetes,2FMHB@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 COG NOG27406 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OMP_b-brl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003279_01169 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 297779 0 0 0 0 0 0 0 0 0 0 0 0 727989 549364 0 0 0 0 0 853434 0 0 0 0 832110 0 0 0 0 0 0 0 0 0 793018 328068 0 304548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343818 0 0 0 0 590789 0 0 0 0 0 0 0 0 0 303294 0 0 634572 0 0 0 0 0 0 0 0 0 0 0 0 351943 634575 0 0 0 0 0 494605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524582 0 279907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 195968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306739 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTLLFGGLESIQHNANRK MGYG000000243_01002;MGYG000002478_03878 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,2FNBF@200643|Bacteroidia,4AM0P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Psort location Cytoplasmic, score 1.0 pheT 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 1.0 6.1.1.20 1.0 ko:K01890 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 B3_4,B5,FDX-ACB,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01002 0.5 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01890:FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] 1.0 none 1.0 0 0 502505 0 356136 0 0 0 0 0 0 0 367892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 574176 0 0 0 0 424799 0 0 209765 0 228757 0 0 0 0 0 0 0 224167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70708 0 0 0 0 147735 0 0 0 0 124874 0 0 0 0 0 0 0 143628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1245659 0 0 524066 0 136997 0 0 0 0 0 0 0 336882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390495 0 0 0 0 432601 0 0 0 0 0 0 0 0 0 0 0 0 9603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7046322 0 0 0 0 0 +(Gln->pyro-Glu)QTLQNIIDR MGYG000002438_02191 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia,22WV0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Trigger factor 1.0 tig 1.0 - 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02191 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 106144 0 0 0 0 0 0 0 0 237113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417699 0 0 0 0 0 0 0 0 406079 0 0 0 0 0 0 0 0 127269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396094 0 0 0 0 0 0 0 0 196981 0 0 0 0 0 0 0 0 216366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338404 0 0 0 0 0 0 0 0 474845 0 0 0 0 0 0 0 0 493106 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTLVHGQGEFHLR MGYG000001345_03238;MGYG000001780_04716;MGYG000000196_03773;MGYG000001313_03098;MGYG000001337_00442;MGYG000003812_01202;MGYG000002171_00598;MGYG000000098_00698;MGYG000002478_00020;MGYG000002051_02357;MGYG000003681_00194;MGYG000001346_00804;MGYG000004823_02933;MGYG000000243_00833;MGYG000001661_00370;MGYG000001378_04098;MGYG000001370_00201;MGYG000003363_00202;MGYG000002455_01659;MGYG000004876_01617;MGYG000004797_02873;MGYG000000054_02613;MGYG000000236_01356;MGYG000004748_03453;MGYG000000013_01898;MGYG000003922_00128 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0480@1|root,COG0480@2|Bacteria,4NG4H@976|Bacteroidetes,2FN1G@200643|Bacteroidia,4AMQX@815|Bacteroidaceae 0.9230769230769231 976|Bacteroidetes 1.0 J 1.0 Psort location Cytoplasmic, score 9.26 0.9230769230769231 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_03238 0.038461538461538464 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 1163229 1426802 1509211 490066 2164639 0 1226509 1323706 1097602 933316 892978 1207183 1504529 1390439 1123440 1707851 1837102 757799 1035787 930335 1124109 1252259 1126003 1450567 1018726 1189171 1451497 0 1342417 1435598 2453200 1618973 1657769 0 1695965 1091825 1204467 1576458 880989 495137 1072650 838055 906183 752596 635450 1091870 1083179 1191881 1499896 1146144 693043 823307 1196986 1252469 1040394 500089 814325 822694 938817 786934 242408 661418 1018922 923523 1037823 380081 727635 1162355 508715 858251 741860 830767 1157369 781369 967275 1009754 860424 1101255 938536 1151606 1507350 1355141 929502 973501 0 1169925 1235206 1353809 984441 1175323 1104023 1085394 1110780 1090298 1256972 993970 905885 1004175 0 1384871 1103691 1264607 1124087 0 936702 958633 1127215 1026372 0 817774 1334934 1145771 1035817 1024438 459045 561976 701758 579526 503012 376925 565557 593718 456166 574460 368287 792872 512307 645178 537868 310642 407290 772261 675179 582894 676664 413738 616761 153644 522766 644158 576892 339374 500375 660796 304518 592643 442328 689361 769006 631791 714176 515471 904320 761798 1102672 938512 1661760 1247325 0 1251301 1245096 622604 906814 888875 1001583 633032 914061 1429015 877745 1741040 911417 958387 636467 1180666 0 1434139 987945 983635 561955 0 1013779 1075713 0 1050791 738311 1198446 0 684013 1064924 963272 +(Gln->pyro-Glu)QTNAKPVTGR MGYG000000271_00190 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 Signal transducing histidine kinase homodimeric 1.0 cheA 1.0 - 1.0 2.7.13.3 1.0 ko:K03407 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW,H-kinase_dim,HATPase_c,Hpt,P2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00190 1.0 histidine kinase. protein kinase (histidine). This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine).-!-A number of histones can act as acceptor. ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03407:cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTSTNYEEASNPISTNPSLWVK MGYG000000243_00778 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3934@1|root,COG3934@2|Bacteria,4NF13@976|Bacteroidetes,2FNPI@200643|Bacteroidia,4ANXT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Domain of unknown function (DUF4091) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4091 1.0 3.2.1.53|3.2.1.- 1.0 GH123 1.0 GH123 1.0 GH123 1.0 MGYG000000243_00778 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 618222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850966 0 717598 0 0 0 0 609371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTTFGELDK MGYG000001157_01000;MGYG000004732_01389;MGYG000003937_01090;MGYG000002619_02238;MGYG000001300_00294;MGYG000004866_01549;MGYG000000022_01323;MGYG000001255_01113;MGYG000002272_01496;MGYG000003166_01335;MGYG000002040_01716 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 0.9090909090909091 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 0.9090909090909091 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001157_01000 0.09090909090909091 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 229842 519185 568887 0 0 266268 238398 0 420125 0 0 0 777961 402278 600115 0 162604 0 930439 872327 0 770452 0 413416 129391 382221 622235 0 0 0 0 0 0 680567 371780 0 491057 0 1033768 1361120 1210224 0 757798 1523758 1733741 0 1449779 0 0 1596331 887171 1439679 944037 0 953344 0 1976156 1505591 0 958012 0 1383702 1554268 1250700 1101546 0 0 1258777 1422452 1102722 1026511 940290 428788 918296 1034271 1332191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239985 0 0 0 0 0 0 0 214857 0 0 0 0 479753 509928 814729 0 900357 701865 821114 0 790672 0 0 706519 856557 787587 319166 0 612994 0 1021523 536760 0 428240 0 266082 366891 601224 398833 0 0 666353 805895 574244 867363 619702 0 647447 444638 966689 0 0 97211 0 0 192065 0 0 117562 0 0 189537 299576 0 0 0 113450 0 0 181646 0 309876 0 0 101281 84706 108171 0 0 312290 0 151117 0 0 317685 0 0 126420 +(Gln->pyro-Glu)QTTFGELDKIC(Carbamidomethyl)KPE MGYG000003937_01090;MGYG000001300_00294;MGYG000003166_01335 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01090 0.3333333333333333 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 854232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 750408 0 0 0 0 1384735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTTFNDMIK MGYG000000235_01320;MGYG000002506_04114;MGYG000002534_04109;MGYG000002515_04341 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0813@1|root,COG0813@2|Bacteria,1MUW6@1224|Proteobacteria,1RMMA@1236|Gammaproteobacteria,3WWYQ@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Phosphorylase superfamily 1.0 deoD 1.0 GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 1.0 2.4.2.1 1.0 ko:K03784 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_1997,iB21_1397.B21_04226,iE2348C_1286.E2348C_4682,iEC042_1314.EC042_4881,iECABU_c1320.ECABU_c50190,iECBD_1354.ECBD_3636,iECB_1328.ECB_04260,iECD_1391.ECD_04260,iECED1_1282.ECED1_5255,iECIAI39_1322.ECIAI39_4916,iECNA114_1301.ECNA114_4626,iECO26_1355.ECO26_5590,iECOK1_1307.ECOK1_4950,iECP_1309.ECP_4768,iEcolC_1368.EcolC_3672,iLF82_1304.LF82_0467,iNRG857_1313.NRG857_22170,iPC815.YPO0440,iSFV_1184.SFV_4418,iSF_1195.SF4416,iSFxv_1172.SFxv_4809,iS_1188.S4687,iUMN146_1321.UM146_22680,iUMNK88_1353.UMNK88_5303,iUTI89_1310.UTI89_C5155,ic_1306.c5468 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000235_01320 0.25 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Nicotinate and nicotinamide metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K03784:deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTTTVTSIETFHK MGYG000002395_00576;MGYG000003452_00658 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002395_00576 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 717324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1286085 0 1313874 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTVAKPVTNR MGYG000002517_01392 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 Signal transducing histidine kinase homodimeric 1.0 cheA 1.0 - 1.0 2.7.13.3 1.0 ko:K03407 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW,H-kinase_dim,HATPase_c,Hpt,P2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01392 1.0 histidine kinase. protein kinase (histidine). This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine).-!-A number of histones can act as acceptor. ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03407:cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] 1.0 none 1.0 0 0 171827 0 0 0 0 0 356392 0 0 103690 0 0 546035 0 0 0 0 0 0 0 0 0 0 0 159513 0 0 406254 0 0 187264 375426 0 0 0 339560 0 0 226247 0 0 0 0 0 379246 0 0 78482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 97337 0 0 0 0 0 217053 242763 0 0 0 139580 0 0 0 0 0 0 0 0 405731 0 0 246823 0 0 630013 0 0 0 0 0 0 0 0 0 0 0 531844 0 0 498771 0 0 0 367820 0 0 0 0 0 0 0 0 0 0 0 0 2519819 0 0 1247353 0 0 2900285 0 0 0 0 0 0 0 0 0 0 0 2179407 0 0 1822938 0 0 0 1464807 0 0 0 0 0 0 1492879 0 0 0 0 0 1755830 0 0 1611564 0 0 1889187 0 0 0 0 0 0 0 0 0 0 0 1153163 0 0 963472 0 0 1173381 1555839 0 0 0 1269799 +(Gln->pyro-Glu)QTVDPAVKAPEVTDK MGYG000002619_00997;MGYG000002545_01731;MGYG000002610_01679;MGYG000003291_00558;MGYG000001300_01680;MGYG000002040_01831;MGYG000003166_01503;MGYG000002272_02058;MGYG000001255_01666 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4,Fer4_10,Fer4_4,Fer4_7,Fer4_8,Fer4_9,MTHFR_C,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002619_00997 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03615:rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390002 0 0 0 0 0 0 283546 0 0 0 0 0 0 0 0 0 0 274386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTVEEVLSSIGPVVDAHPEYEKVALLER MGYG000000233_02492 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,222GB@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02492 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTVNEIGYNDAK MGYG000002517_00444 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25V3W@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme 1.0 metK 1.0 - 1.0 2.5.1.6 1.0 ko:K00789 1.0 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 1.0 M00034,M00035,M00368,M00609 1.0 R00177,R04771 1.0 RC00021,RC01211 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N,YgbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00444 1.0 methionine adenosyltransferase. S-adenosylmethionine synthetase. Formerly EC 2.4.2.13. ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L- methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00789:metK, MAT; S-adenosylmethionine synthetase [EC:2.5.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633083 0 0 0 0 0 0 0 415352 0 0 0 0 0 0 0 0 223969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTVYTASPESQQIHVWSLNHDGSLK MGYG000002494_00779 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2706@1|root,COG2706@2|Bacteria,1MWGS@1224|Proteobacteria,1RNX2@1236|Gammaproteobacteria,3XMN9@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate 1.0 pgl 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689 1.0 3.1.1.31 1.0 ko:K07404 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 1.0 M00004,M00006,M00008 1.0 R02035 1.0 RC00537 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iSSON_1240.SSON_0741 1.0 Lactonase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00779 1.0 6-phosphogluconolactonase. - - 6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K07404:pgl; 6-phosphogluconolactonase [EC:3.1.1.31] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 555287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTYAFAAGTKK MGYG000002528_02671 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Acetyl-CoA hydrolase transferase 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02671 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 535160 0 0 0 222635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1486551 0 0 0 264875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 913755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QTYAFGAGTKK MGYG000002517_02708;MGYG000000164_00689 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Acetyl-CoA hydrolase transferase 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02708 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 820860 650922 0 0 0 0 0 0 0 266331 547851 1698559 0 1188659 1304379 0 0 0 0 0 0 0 0 660386 0 0 0 0 1245132 0 0 352767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230249 0 279135 0 0 371883 0 0 0 0 0 0 0 0 0 0 0 0 0 662831 0 0 372489 0 0 0 0 527694 0 0 738375 0 0 0 0 0 0 0 762842 1228761 757525 0 2338573 706906 0 0 0 0 0 0 0 0 2933256 0 0 0 0 2044689 0 0 527155 0 0 0 0 492265 0 1650382 0 0 0 0 0 0 0 0 2064314 2956527 664610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1914681 0 0 0 0 0 +(Gln->pyro-Glu)QVAAGSGC(Carbamidomethyl)YTHVVENTAR MGYG000000262_02783;MGYG000000262_02732;MGYG000000077_00328 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,25UUE@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Carbon-monoxide dehydrogenase, catalytic subunit 1.0 cooS 1.0 - 1.0 1.2.7.4 1.0 ko:K00198 1.0 ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200 1.0 M00377 1.0 R07157,R08034 1.0 RC00250,RC02800 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Prismane 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02783 0.3333333333333333 anaerobic carbon-monoxide dehydrogenase. Ni-CODH. This prokaryotic enzyme catalyzes the reversible reduction of CO2 to CO.-!-The electrons are transferred to redox proteins such as ferredoxin.-!-In purple sulfur bacteria and methanogenic archaea it catalyzes the oxidation of CO to CO2, which is incorporated by the Calvin-Benson- Basham cycle or released, respectively.-!-In acetogenic and sulfate-reducing microbes it catalyzes the reduction of CO2 to CO, which is incorporated into acetyl CoA by EC 2.3.1.169, with which the enzyme forms a tight complex in those organisms.-!-In purple sulfur bacteria the enzyme forms complexes with the Ni-Fe-S protein EC 1.12.7.2 which catalyze the overall reaction: CO + H2O = CO2 + H2. cf. EC 1.2.5.3.-!-Formerly EC 1.2.99.2. CO + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + 2 H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Nitrotoluene degradation|Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00198:cooS, acsA; anaerobic carbon-monoxide dehydrogenase catalytic subunit [EC:1.2.7.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 649218 0 0 0 527841 0 0 0 0 0 0 0 0 0 510435 0 0 0 0 0 545067 0 0 0 0 0 0 0 0 0 0 0 528923 609445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220856 0 0 0 0 0 0 0 0 0 0 0 0 0 623511 0 0 0 0 0 487429 0 503647 0 0 0 0 0 0 668681 0 0 309198 147979 0 0 0 +(Gln->pyro-Glu)QVAEGALNETHSILQR MGYG000000187_02828;MGYG000000389_01367;MGYG000000076_03207;MGYG000001186_01647;MGYG000004317_00523 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000187_02828 0.2 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 7761711 3737731 8016070 14693557 8584396 6344447 5167425 10675297 0 0 0 8683824 9019580 0 9002966 8184428 0 0 15431893 6777325 8204203 5164995 0 6891220 8403339 10085061 12498496 0 1780821 13598834 4821542 3841687 5297295 8982098 8439476 7983035 9381683 5111340 569027 310183 285161 435076 318820 588744 0 411517 464489 0 0 292134 601254 1078503 378239 610620 405437 0 495364 0 479425 208605 0 0 956572 426400 299108 0 463930 1349371 0 0 365591 566343 392343 376554 222118 268439 5777634 2064509 963690 5130466 3570042 2511638 4726172 5773421 7317665 0 0 8352811 5673363 6002783 6669721 3863906 3881943 0 5717203 4281466 3720145 910401 0 1229322 8623629 10908519 6468833 0 1303037 5602489 2308597 1153355 1505340 4651872 8201250 7253646 10414819 1154902 0 0 433438 0 680384 263518 1169236 320793 832197 0 0 284487 306405 0 265642 215241 254803 0 0 348167 401200 206476 0 0 346157 252612 0 0 237931 0 281933 236876 252129 322507 316621 0 209568 211446 580209 0 2204757 558959 290677 1626263 1038475 78406 518703 0 0 0 239080 0 259782 71566 390808 0 330365 286812 0 160637 0 253168 298683 344821 0 0 210210 409237 0 0 899241 335026 194092 489880 290876 0 +(Gln->pyro-Glu)QVAEGALSETHSILQR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00135 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 1234408 1025448 1145438 1310671 1712010 1174216 1488883 1678960 2312541 2173309 954612 1414835 1382776 2240344 1218508 1599271 1887047 0 1438302 802149 1139117 986954 0 1214725 1349891 1350572 1117389 0 1312802 1595376 1645272 1318416 956420 1569829 1521121 1401671 1930214 1071807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261824 0 0 0 0 0 0 0 0 0 0 301257 0 0 0 0 0 20367219 5647117 6523086 28385475 16392607 8393000 15487654 47690690 37586166 13744129 11080328 21793850 10573421 46633871 51538328 13918975 20499157 0 29263112 21027388 21302577 2893022 0 2690542 51294205 48637216 33913144 0 6240426 28102582 6207312 8846478 5149577 39812043 37863310 30589603 45122988 6209053 15741562 8141936 14112612 5921404 15378940 20539931 6431544 9834132 13880725 24608500 16993519 11916432 25355895 14666562 20780251 11543627 16376325 0 18658255 15968572 12345665 12803547 0 23611262 20768116 18941575 23847768 0 5703304 21340849 15310574 8791279 17929295 22414343 22280906 12262389 30971009 23071790 +(Gln->pyro-Glu)QVAILAVAGAEK MGYG000002494_02408;MGYG000002506_03406;MGYG000000235_03967;MGYG000002534_04893;MGYG000002477_00658;MGYG000002323_04219;MGYG000002535_04275 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0711@1|root,COG0711@2|Bacteria,1RHZ0@1224|Proteobacteria,1S402@1236|Gammaproteobacteria,3X0ZA@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) 1.0 atpF 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031225,GO:0032991,GO:0033177,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902600 1.0 - 1.0 ko:K02109 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 e_coli_core.b3736,iAF1260.b3736,iB21_1397.B21_03564,iBWG_1329.BWG_3427,iE2348C_1286.E2348C_4046,iEC042_1314.EC042_4123,iEC55989_1330.EC55989_4211,iECABU_c1320.ECABU_c42210,iECBD_1354.ECBD_4296,iECB_1328.ECB_03620,iECDH10B_1368.ECDH10B_3923,iECDH1ME8569_1439.ECDH1ME8569_3624,iECD_1391.ECD_03620,iECED1_1282.ECED1_4426,iECH74115_1262.ECH74115_5172,iECIAI1_1343.ECIAI1_3920,iECIAI39_1322.ECIAI39_4340,iECO103_1326.ECO103_4422,iECO111_1330.ECO111_4570,iECO26_1355.ECO26_4842,iECOK1_1307.ECOK1_4185,iECP_1309.ECP_3935,iECS88_1305.ECS88_4158,iECSE_1348.ECSE_4026,iECSF_1327.ECSF_3584,iECSP_1301.ECSP_4786,iECUMN_1333.ECUMN_4266,iECW_1372.ECW_m4039,iECs_1301.ECs4678,iEKO11_1354.EKO11_4609,iETEC_1333.ETEC_4027,iEcDH1_1363.EcDH1_4231,iEcE24377_1341.EcE24377A_4252,iEcHS_1320.EcHS_A3952,iEcSMS35_1347.EcSMS35_4104,iEcolC_1368.EcolC_4258,iG2583_1286.G2583_4532,iJO1366.b3736,iJR904.b3736,iSDY_1059.SDY_4012,iSFV_1184.SFV_3762,iSF_1195.SF3816,iSFxv_1172.SFxv_4159,iSSON_1240.SSON_3883,iS_1188.S3952,iSbBS512_1146.SbBS512_E4185,iUMN146_1321.UM146_18870,iUMNK88_1353.UMNK88_4548,iUTI89_1310.UTI89_C4291,iWFL_1372.ECW_m4039,iY75_1357.Y75_RS18390,iZ_1308.Z5234,ic_1306.c4664 1.0 ATP-synt_B 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02408 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02109:ATPF0B, atpF; F-type H+-transporting ATPase subunit b 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381763 380362 0 389821 662058 0 0 0 437959 0 0 0 0 0 0 591108 0 470964 0 0 779308 0 678120 0 0 0 0 473477 0 0 0 327002 0 0 0 0 251248 0 0 0 0 0 189941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 149984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64978 0 0 0 0 105402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVAIVKR MGYG000004797_02827;MGYG000001056_01201;MGYG000004899_03971;MGYG000003697_01312;MGYG000002737_00135;MGYG000000196_04055;MGYG000001787_00508;MGYG000000243_00691;MGYG000002293_02133;MGYG000002478_00464;MGYG000000215_00958;MGYG000001313_02959;MGYG000000098_03787 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,2FMKX@200643|Bacteroidia,4AMQC@815|Bacteroidaceae 0.6153846153846154 976|Bacteroidetes 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO,NanE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_02827 0.07692307692307693 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVC(Carbamidomethyl)ETLEK MGYG000000142_02834;MGYG000002279_01986;MGYG000000184_00575;MGYG000004785_01840;MGYG000000031_02405;MGYG000001338_02151;MGYG000002203_00507 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.7142857142857143 186801|Clostridia 0.8571428571428571 G 0.8571428571428571 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 0.7142857142857143 ppdK 0.8571428571428571 - 1.0 2.7.9.1 0.8571428571428571 ko:K01006 0.8571428571428571 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.8571428571428571 M00169,M00171,M00172,M00173 0.8571428571428571 R00206 0.8571428571428571 RC00002,RC00015 0.8571428571428571 ko00000,ko00001,ko00002,ko01000 0.8571428571428571 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.8571428571428571 - 1.0 - 1.0 - 1.0 GT1 0.8571428571428571 MGYG000000142_02834 0.14285714285714285 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 0.8571428571428571 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 0.8571428571428571 none 1.0 0 239351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116924 0 0 0 0 0 0 0 495013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1119562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1345961 0 0 0 0 0 0 0 577410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 620935 0 0 0 0 0 0 0 1355896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1175111 0 0 0 0 0 0 +(Gln->pyro-Glu)QVC(Carbamidomethyl)ETLEKHYR MGYG000000142_02834;MGYG000002279_01986;MGYG000000031_02405;MGYG000001338_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.75 186801|Clostridia 1.0 G 1.0 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 0.75 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000142_02834 0.25 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVC(Carbamidomethyl)QTLEDHYR MGYG000000077_02459 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum soehngenii|m__MGYG000000077 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25VEG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000077_02459 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 638586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVDDKVLAALVK MGYG000002517_02936 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 2.2.1.2,5.3.1.9 1.0 ko:K01810,ko:K13810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00004,M00007,M00114 1.0 R01827,R02739,R02740,R03321 1.0 RC00376,RC00439,RC00563,RC00604 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02936 1.0 transaldolase. | glucose-6-phosphate isomerase. glycerone transferase. | phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]|K13810:tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 91459 115411 184292 0 0 0 107814 183158 0 180571 0 185938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89108 125607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109079 0 0 0 0 0 0 0 0 78419 0 0 0 0 0 85041 104100 0 0 0 0 0 0 0 0 81491 0 74832 0 916632 0 156575 0 0 293862 501966 1341817 1081567 632612 368859 503524 0 1208288 1507195 0 724627 0 1021491 0 0 0 0 0 1125506 1293356 0 0 0 0 216615 0 209475 846480 1134178 961035 1398633 129323 502536 0 951172 0 0 914061 689579 389047 605078 978612 555656 673692 0 755549 849475 0 855769 0 629156 0 0 445855 0 532897 687732 679702 0 0 0 0 471689 0 910216 481004 743910 776572 766851 642167 +(Gln->pyro-Glu)QVDNVLDGVAFELLGK MGYG000002517_00544 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00544 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 251146 0 0 0 0 0 0 778181 0 0 0 0 0 0 0 0 0 0 330859 0 0 0 354256 0 0 0 0 0 0 357668 0 453137 0 0 0 0 0 0 1047168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2805356 485507 0 0 0 0 0 0 0 0 0 0 0 0 244471 0 0 0 0 0 0 204381 0 0 0 0 0 0 1182055 0 0 0 0 0 0 0 0 0 2376782 0 0 0 0 210293 0 0 0 0 0 0 0 0 1980776 0 0 0 0 0 0 2384712 0 0 0 0 0 0 2755694 0 0 0 0 0 0 0 0 0 1929186 2186822 0 0 0 3233882 0 0 0 0 0 0 2126771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVEAEETTK MGYG000004712_00508;MGYG000000200_01193;MGYG000002312_00710;MGYG000004785_01922;MGYG000001338_00217;MGYG000002989_00657;MGYG000000356_00231;MGYG000003215_00942 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia 0.5 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004712_00508 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04078:groES, HSPE1; chaperonin GroES 1.0 none 1.0 0 489437 233632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168595 563435 248288 0 0 0 0 310491 0 877265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 944349 511385 0 0 0 0 0 0 0 556146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 601354 0 0 0 0 0 0 0 553926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 818127 475670 387251 0 0 0 0 330055 0 743467 353011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608004 1092345 694262 0 0 0 0 325294 +(Gln->pyro-Glu)QVEEAGGKVELK MGYG000002720_01642;MGYG000004487_00623;MGYG000002143_01057;MGYG000002156_00936 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2N7E0@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01642 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 1283835 1395268 0 0 0 1397602 0 780082 0 0 0 0 0 1748795 0 0 0 0 0 0 0 1582411 0 1635485 1087362 1220421 0 0 0 0 0 0 0 0 0 1355613 1405096 0 670566 157245 0 0 0 0 0 0 0 0 0 0 0 181279 0 0 0 0 0 0 0 351336 0 0 0 0 0 0 0 0 0 0 0 0 0 444957 540139 0 799836 0 0 0 0 0 0 0 0 0 0 0 0 612436 0 0 0 0 0 0 0 0 0 0 0 350062 0 0 0 0 0 0 0 0 0 0 350222 0 749947 948602 0 0 0 1025161 0 1243306 0 0 0 0 0 1091259 0 0 0 0 0 0 0 934644 0 1141785 1381202 1572596 0 0 0 0 0 0 0 0 0 1334752 1288261 0 0 0 0 0 0 0 0 145681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVEEEIIETGKR MGYG000001780_03543 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__|m__MGYG000001780 1.0 COG1418@1|root,COG1418@2|Bacteria,4NE3V@976|Bacteroidetes,2FKZ6@200643|Bacteroidia,4AKD2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Endoribonuclease that initiates mRNA decay 1.0 rny 1.0 - 1.0 - 1.0 ko:K18682 1.0 ko03018,map03018 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03019 1.0 - 1.0 - 1.0 - 1.0 DUF3552,HD,KH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001780_03543 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation 1.0 K18682:rny; ribonucrease Y [EC:3.1.-.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 660749 703682 0 736001 0 0 0 0 0 0 0 0 0 0 604416 0 0 0 0 0 0 0 0 600607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378812 300821 0 0 0 0 0 0 0 0 0 0 0 0 273911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316779 0 0 347403 0 0 0 0 0 0 0 0 0 0 274466 0 0 0 0 0 0 0 0 345570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534936 0 0 719601 0 0 0 0 0 0 0 0 0 0 596287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435986 0 0 181484 0 0 0 0 0 0 0 0 0 0 167735 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVEEVGGKVELK MGYG000002926_01367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2N7E0@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_01367 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 322803 0 0 301713 0 0 339389 169369 402861 0 0 0 0 248795 307978 0 0 0 0 0 0 0 0 0 346829 243348 0 0 0 0 0 0 301747 398212 0 0 0 0 0 0 0 310097 0 0 246448 357269 0 316397 0 0 0 0 228055 0 0 0 0 0 0 0 0 0 0 323031 534204 0 0 0 0 0 0 229055 448486 0 400725 230452 1138625 0 901289 1061751 0 0 1012586 1262467 1161741 1034123 0 0 1176672 1007429 1181820 0 0 0 1206314 1034576 800607 0 0 0 975415 1255278 1199229 0 837950 0 0 0 851180 1064892 1269481 0 1169116 714935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVEFITEQYKR MGYG000002528_01102 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,267JY@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000002528_01102 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 437171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410989 0 315504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618053 0 0 0 410263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603296 0 307044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396774 0 221005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVFAEKPAEFDPR MGYG000002575_01735;MGYG000001306_00718;MGYG000000273_02673 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.6666666666666666 976|Bacteroidetes 1.0 G 0.6666666666666666 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.6666666666666666 fba 0.6666666666666666 - 1.0 4.1.2.13 0.6666666666666666 ko:K01624 0.6666666666666666 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6666666666666666 M00001,M00003,M00165,M00167,M00344,M00345 0.6666666666666666 R01068,R01070,R01829,R02568 0.6666666666666666 RC00438,RC00439,RC00603,RC00604 0.6666666666666666 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002575_01735 0.3333333333333333 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6666666666666666 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 680524 0 0 909401 0 0 0 0 0 2838084 0 0 0 0 4130826 0 0 0 0 4389663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVFGEDTDVKDEAAFR MGYG000003697_01308;MGYG000002960_01695;MGYG000002080_00708;MGYG000002834_01496 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 O 1.0 Trigger factor 1.0 tig 1.0 - 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01308 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1222268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802725 0 0 0 0 1153333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVFGVTFEQGR MGYG000002528_02568;MGYG000002992_01014;MGYG000002603_01825;MGYG000000171_02639;MGYG000000212_00042;MGYG000002279_00204;MGYG000000233_01645;MGYG000000142_02311;MGYG000000201_03105;MGYG000002960_01934;MGYG000000255_00249;MGYG000000205_01720;MGYG000003697_02648;MGYG000002293_00459;MGYG000000028_00883;MGYG000000216_01228;MGYG000002834_02512 domain d__Bacteria 1.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3XYNE@572511|Blautia 0.4117647058823529 186801|Clostridia 0.7058823529411765 F 1.0 AICARFT IMPCHase bienzyme 0.47058823529411764 purH 0.7058823529411765 - 1.0 2.1.2.3,3.5.4.10 1.0 ko:K00602 1.0 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 1.0 M00048 1.0 R01127,R04560 1.0 RC00026,RC00263,RC00456 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 AICARFT_IMPCHas 0.8235294117647058 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02568 0.058823529411764705 phosphoribosylaminoimidazolecarboxamide formyltransferase. | IMP cyclohydrolase. aminoimidazolecarboxamide ribonucleotide transformylase. | inosinicase. - (6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D- ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. | H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. 1.0 1.0 1.0 1.0 Purine metabolism|One carbon pool by folate|Metabolic pathways|Biosynthesis of secondary metabolites|Antifolate resistance 1.0 K00602:purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVGLGHGNLGAR MGYG000001300_02120;MGYG000002274_00309;MGYG000000039_01269 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02120 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2108676 2261719 3090271 2463389 1161202 2271037 1477040 1495151 2170793 2026440 1592341 746537 2672406 2730697 2149273 2705203 2241991 3719966 3735892 2878168 1031627 2383122 2758514 1729451 2305377 1883504 2171051 3107657 0 1250994 2068062 1558652 3003500 3299348 1162193 2217014 1739529 2436628 6874881 3220570 5162792 5906133 2499768 3809686 7112639 2814229 7638691 1806060 2702308 4228003 3289190 6074847 5391569 3406278 6317385 4005252 6541033 6044580 2545335 2790478 4636992 3336988 7472929 5995613 6202257 4887387 0 3947215 4366958 2711884 4948801 6332890 2884345 5787166 6289782 5066047 1815293 1145070 811261 1666337 1353499 1316425 1604942 1614179 1718320 1388707 1615230 1163151 1644610 1748213 1865524 1447037 1126888 4140665 1538575 1511675 1636109 749502 4345087 1382031 1551066 1470843 1708147 5053185 0 1634711 1271573 1487599 892670 1966865 1009191 1621399 1400052 1239329 3346898 2800444 5656540 3713291 3852568 4476691 5362422 2040235 4001639 3141500 3912254 4277681 5369729 3682634 3486529 3794106 3399570 4664347 5448164 4051843 3314771 4627482 4997512 3955824 3889169 3762426 3136786 4447521 0 4682201 4292699 3391768 4665613 5357898 1444389 3387682 3317833 4788247 829251 563405 1150730 784778 967899 745736 516065 877215 729402 767463 431636 1022865 883985 805488 773835 711273 748003 3256835 632950 825924 1085186 731766 3742577 488825 825700 750764 654638 4176017 0 837980 651033 895347 1025309 787856 159979 865777 684733 1314573 +(Gln->pyro-Glu)QVGQTGVTVRPK MGYG000001415_00122;MGYG000000074_02401;MGYG000002867_00909 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 - 1.0 ko:K03522 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_00122 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit 1.0 none 1.0 232175 0 0 0 0 373633 0 0 295291 0 0 0 0 0 557272 0 375940 0 521854 229727 0 0 0 264314 0 500056 0 0 155467 543038 0 0 333929 0 0 337138 277821 0 204993 0 342519 0 0 200431 0 432873 430115 0 0 0 0 0 315770 0 0 0 448428 375449 0 0 0 0 0 211243 0 0 324641 403120 0 0 324199 0 0 295391 293123 396769 224440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332869 0 0 0 0 0 0 0 0 0 0 241243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265451 242573 0 0 0 0 0 347371 0 0 0 0 159030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740405 0 788963 0 0 861125 0 828146 922001 0 0 0 0 0 760618 0 840612 0 1433553 1450003 0 602692 0 795638 0 1479016 0 0 753087 1191593 0 0 344753 0 0 722801 966860 724811 +(Gln->pyro-Glu)QVGVPYIIVFLNK MGYG000003486_01055;MGYG000002492_00344;MGYG000002515_03208;MGYG000002515_03657;MGYG000004704_00398;MGYG000001635_01137;MGYG000002506_03686;MGYG000000412_01546;MGYG000002506_02966;MGYG000000045_02616;MGYG000001400_03001;MGYG000000121_02189 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,3ZITI@590|Salmonella 0.3333333333333333 186801|Clostridia 0.3333333333333333 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.6666666666666666 tuf 1.0 - 0.8333333333333334 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003486_01055 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2479700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152140831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVGVPYIVVFLNK MGYG000002854_00111;MGYG000002106_00224;MGYG000003425_03741;MGYG000000245_03248;MGYG000004724_00878;MGYG000001567_01738;MGYG000002563_00522;MGYG000000404_00531;MGYG000001507_06245;MGYG000000291_00377;MGYG000002126_00299;MGYG000003411_00716;MGYG000000266_00259;MGYG000000919_01815;MGYG000002854_00124;MGYG000001299_01777;MGYG000001623_00993;MGYG000004221_01651;MGYG000002563_00509;MGYG000003266_00392;MGYG000000157_01091;MGYG000003073_01160;MGYG000002042_00774;MGYG000002517_00205;MGYG000001485_02164;MGYG000000223_03134 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CUFV@84998|Coriobacteriia 0.2692307692307692 186801|Clostridia 0.5384615384615384 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9230769230769231 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.9615384615384616 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002854_00111 0.038461538461538464 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 583291 0 0 0 0 1612212 261024 218859 254680 0 0 4064792 0 0 612126 2374890 0 0 0 0 2759797 0 0 751533 2692605 448912 135275 0 0 0 0 0 0 0 4500203 229219 1483943 238757 14040243 0 6810290 0 0 353916 6013683 23166481 0 452555 0 0 0 7375463 14234140 0 486028 0 0 0 0 0 0 0 31248932 0 7976119 0 0 0 0 0 20534142 0 31260598 12060434 13548685 26202013 960126 0 0 0 0 0 1429329 1639398 1146541 1449628 0 0 0 0 2667977 4390273 3306914 0 0 0 4534269 0 0 0 2260297 3222640 1179883 0 0 0 0 0 0 2196679 3251177 966028 2013597 0 5249339 0 914400 0 0 0 2244818 1420952 5018462 1529999 0 2937904 0 1615322 5773866 4438931 2190800 0 2252528 0 5256485 4880973 0 0 4488991 5025899 1581795 0 0 0 0 0 8957205 0 1798812 2860931 5834582 5115095 9093962 0 19736896 0 13323840 7466847 8221832 2634890 7487794 7886630 0 7717255 0 7974354 5714652 4764924 11162908 0 7078719 0 4552297 2872597 0 10679205 6566055 5986877 10427504 0 0 0 0 0 9767457 3627462 8989509 11189067 4000969 2392929 +(Gln->pyro-Glu)QVGVPYIVVFMNK MGYG000000080_02058;MGYG000000171_02844;MGYG000001673_01975;MGYG000000089_01901;MGYG000001688_04229;MGYG000002619_00483;MGYG000001654_02237;MGYG000004718_00646;MGYG000004735_00884;MGYG000000280_01200;MGYG000001714_01291;MGYG000001760_00949;MGYG000000198_01165;MGYG000000392_00966;MGYG000000133_02991;MGYG000003185_01074;MGYG000002202_00030;MGYG000003895_00135;MGYG000001619_01314;MGYG000000216_02406;MGYG000000034_01346;MGYG000004296_01668;MGYG000003549_00407;MGYG000001809_00576;MGYG000001652_01300;MGYG000000127_03982;MGYG000000258_00266;MGYG000001338_03373;MGYG000001300_00280;MGYG000001611_00087;MGYG000000255_02009;MGYG000002040_01212;MGYG000000164_01096;MGYG000002234_01026;MGYG000001606_01669;MGYG000000032_01232;MGYG000002105_00002;MGYG000002224_01123;MGYG000000036_01380;MGYG000000262_00030;MGYG000001615_01716;MGYG000000016_02519;MGYG000002279_01932;MGYG000001756_00183;MGYG000000201_03875;MGYG000003063_00662;MGYG000000271_03365;MGYG000000185_02848;MGYG000001315_01207;MGYG000001602_02247;MGYG000003273_00234;MGYG000000140_01590;MGYG000001065_02730;MGYG000000022_02283;MGYG000002528_01098;MGYG000004680_02443;MGYG000001436_02249;MGYG000003899_01642;MGYG000003891_00382;MGYG000000179_00920;MGYG000001749_02490;MGYG000001779_00600;MGYG000000177_01044;MGYG000002290_01325;MGYG000001531_00906;MGYG000001607_01045;MGYG000001141_02439;MGYG000003166_01350;MGYG000000251_00064;MGYG000000233_00807;MGYG000000142_00171;MGYG000002702_01978;MGYG000001528_00736;MGYG000004087_00551;MGYG000001439_02427;MGYG000000242_00282;MGYG000002417_01244;MGYG000000187_02029;MGYG000002641_00069;MGYG000000733_01034;MGYG000001698_04050;MGYG000000212_03313;MGYG000003074_01359;MGYG000003185_01053;MGYG000002837_02416;MGYG000000193_02083;MGYG000002272_01482;MGYG000002212_00196;MGYG000003236_02455;MGYG000001665_01696;MGYG000004630_01824;MGYG000001814_01592;MGYG000003504_00096;MGYG000001617_01406;MGYG000001732_00030;MGYG000000206_00901;MGYG000004733_01211 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.24742268041237114 186801|Clostridia 0.9484536082474226 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9587628865979382 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.9587628865979382 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_02058 0.010309278350515464 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 14071210 0 2996072 6107834 5660032 224315 0 18831506 14557337 6243690 6000937 20034447 0 199139 946707 0 0 9959904 1586893 12670446 21311066 6572949 6602246 7904464 8950914 325021 2260914 9453514 16178567 0 192228 20672450 14056265 9467006 23401947 384061 8091094 786017 320150 297912 624361 3061130 18964878 19213790 0 1080586 4276993 8612972 10020782 574098 0 252427 2281784 0 0 15186981 13476923 12044315 10338258 3730887 2528319 495100 661135 6326305 5482934 923388 4950944 0 8944254 7802516 13103786 3341646 10062492 3566617 6777350 15667192 8933136 7009569 1281426 278219 8235269 8176362 0 0 1822869 4205900 6891925 412158 0 12618022 4744501 0 0 8917281 12544509 9793898 5166534 145015 16514714 7971729 1688178 3613959 189788 15241988 16648892 0 3731413 19733440 12092318 0 16257971 1693165 1890540 4096717 187100 5415335 6279940 0 0 2432040 0 0 3260265 184050 8342334 197354 0 6603345 4434092 0 0 0 5800424 5957532 3583695 5027630 0 4379629 2715411 210585 0 0 2705946 0 4001877 7706516 4766633 5174653 2084368 97638 2105399 3391684 12246439 41568386 17618721 41155468 5069774 3913140 0 16358022 4910673 10160329 38331328 22902770 0 66077962 7950733 0 0 0 9334136 10971335 14934362 26506300 12964200 15831038 20504653 20458431 31422814 15076582 17770810 0 28431194 8805252 64173786 27599446 40454290 11246187 15029040 7010222 +(Gln->pyro-Glu)QVGVPYLVVFMNK MGYG000001412_04734;MGYG000001405_04470;MGYG000001469_02077 class d__Bacteria|p__Firmicutes|c__Bacilli 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,1ZCZK@1386|Bacillus 1.0 91061|Bacilli 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 iSB619.SA_RS02960 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001412_04734 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 17318545 0 0 0 12903784 0 0 0 0 0 0 0 13157664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16791071 0 0 0 650695 0 0 0 0 0 681367 0 0 0 0 0 0 0 0 0 0 0 0 22686738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17913244 0 0 0 0 0 0 0 0 0 0 0 0 0 25113373 0 0 0 0 14570584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431674 0 3760472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVHC(Carbamidomethyl)VNLTESTIEANKR MGYG000002492_02662 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,25VFM@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 - 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_02662 1.0 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K02564:nagB, GNPDA; glucosamine-6-phosphate deaminase [EC:3.5.99.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 923268 0 0 0 0 544675 0 0 0 0 845087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577956 0 0 0 0 858730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVHTISIDPEVIKR MGYG000001306_02264 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001306_02264 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 707492 0 0 0 0 0 0 0 0 0 723673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 61446 0 0 0 0 72715 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVHTLSIDPEVIKR MGYG000001783_01353;MGYG000001306_02264 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001783_01353 0.5 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 580819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135668 0 0 0 0 138116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVHTLSIDPEVIQR MGYG000003693_03082 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000003693_03082 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 949436 0 0 0 0 1493115 0 0 0 0 1136959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520167 0 0 0 0 414362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVIDASHAEGK MGYG000002535_01117;MGYG000002494_03970;MGYG000002506_01938;MGYG000002534_03518;MGYG000002515_00714;MGYG000002502_00289;MGYG000000235_01041;MGYG000002323_02956 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1080@1|root,COG1080@2|Bacteria,1MUT8@1224|Proteobacteria,1RN6R@1236|Gammaproteobacteria,3X15C@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsI 1.0 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006810,GO:0008150,GO:0008643,GO:0008965,GO:0009401,GO:0016740,GO:0016772,GO:0016775,GO:0019197,GO:0032991,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0051179,GO:0051234,GO:0071702 1.0 2.7.3.9 1.0 ko:K08483 1.0 ko02060,map02060 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 iB21_1397.B21_02277,iE2348C_1286.E2348C_2602,iEC042_1314.EC042_2625,iECBD_1354.ECBD_1265,iECB_1328.ECB_02316,iECD_1391.ECD_02316,iECH74115_1262.ECH74115_3647,iECIAI1_1343.ECIAI1_2474,iECIAI39_1322.ECIAI39_2562,iECO103_1326.ECO103_2935,iECO111_1330.ECO111_3146,iECO26_1355.ECO26_3469,iECP_1309.ECP_2440,iECSE_1348.ECSE_2707,iECSP_1301.ECSP_3364,iECUMN_1333.ECUMN_2738,iECW_1372.ECW_m2645,iECs_1301.ECs3288,iEKO11_1354.EKO11_1312,iEcE24377_1341.EcE24377A_2703,iEcHS_1320.EcHS_A2551,iEcSMS35_1347.EcSMS35_2571,iEcolC_1368.EcolC_1262,iLF82_1304.LF82_1770,iNRG857_1313.NRG857_12115,iSBO_1134.SBO_2440,iSDY_1059.SDY_2613,iSFV_1184.SFV_2468,iSF_1195.SF2471,iSFxv_1172.SFxv_2720,iSSON_1240.SSON_2505,iS_1188.S2617,iUMNK88_1353.UMNK88_3018,iWFL_1372.ECW_m2645,iZ_1308.Z3682 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002535_01117 0.125 phosphoenolpyruvate--protein phosphotransferase. sugar--PEP phosphotransferase enzyme I. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 K08483:ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] 1.0 none 1.0 0 231269 121134 0 0 591392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493041 0 558148 0 0 0 0 0 0 0 0 294347 0 0 0 0 0 0 1116141 1254979 0 0 1933236 0 0 0 0 0 0 0 905129 0 0 0 0 1288120 0 0 2135998 0 0 0 0 0 0 0 0 0 0 1444319 0 0 0 0 1185689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 570345 0 634703 0 0 0 0 0 0 0 0 358776 0 0 0 0 0 0 443462 1063828 0 0 1141260 0 0 0 0 0 0 0 746988 0 0 0 0 960989 0 0 1175307 0 848064 0 0 0 0 0 0 0 0 988453 0 0 0 0 1043468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVIETM(Oxidation)EKLDTSDPEYIK MGYG000000198_03147 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,21Y97@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_03147 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVIHQDAIEAEGK MGYG000000133_00139 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 pgcA 1.0 - 1.0 5.4.2.2,5.4.2.8 1.0 ko:K01835,ko:K01840 1.0 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00114,M00549 1.0 R00959,R01057,R01818,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Alpha-amylase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000133_00139 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). | phosphomannomutase. phosphoglucose mutase. | phosphomannose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. | alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. | alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2]|K01840:manB; phosphomannomutase [EC:5.4.2.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 902282 0 0 0 0 0 0 0 0 607394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 813451 0 0 0 0 0 0 0 0 0 0 1223908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 933712 0 0 0 1231023 0 0 883568 0 621642 +(Gln->pyro-Glu)QVIMIDAAGPR MGYG000001300_01685 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1149@1|root,COG2878@1|root,COG1149@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,3WIFS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 electron transport complex, RnfABCDGE type, B subunit 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_13,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_01685 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03616:rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 356195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246078 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVIQFIDLSLITK MGYG000002506_00089;MGYG000002494_00829;MGYG000002515_00914 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,1RR4N@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 P 1.0 During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction 1.0 dps 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005623,GO:0006950,GO:0008150,GO:0008199,GO:0009289,GO:0009295,GO:0009605,GO:0009991,GO:0031667,GO:0042594,GO:0042802,GO:0042995,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0097159,GO:1901363 1.0 - 1.0 ko:K04047 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03036 1.0 - 1.0 - 1.0 - 1.0 Ferritin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00089 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04047:dps; starvation-inducible DNA-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208884 0 0 0 0 0 0 0 0 1904016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1740027 0 0 0 0 0 2704365 1058284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 743265 0 0 0 0 0 0 300621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVITSFAGLR MGYG000001564_01807;MGYG000002298_00538;MGYG000000038_01495;MGYG000000274_03210;MGYG000000280_01802;MGYG000000133_01814;MGYG000000404_00180;MGYG000004552_00557;MGYG000004691_01133;MGYG000001619_01503;MGYG000002312_03079;MGYG000001710_03464;MGYG000000171_00187;MGYG000000255_01681;MGYG000001493_05221;MGYG000001186_01771;MGYG000002290_01418;MGYG000000271_03444;MGYG000001683_00852;MGYG000002186_01068;MGYG000004548_00016;MGYG000000909_00226;MGYG000000301_00532;MGYG000000252_02426;MGYG000002517_00473;MGYG000001311_02981;MGYG000000489_00238;MGYG000000154_01590;MGYG000000076_01007;MGYG000000153_02080;MGYG000004087_02481;MGYG000000249_02126;MGYG000000245_01076;MGYG000000205_00110;MGYG000002276_00835;MGYG000003074_00570;MGYG000001622_01941;MGYG000000127_02775;MGYG000000179_02173;MGYG000002279_02522;MGYG000001315_01114;MGYG000004271_01228;MGYG000002105_01104;MGYG000000212_00378;MGYG000000198_04022 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 0.28888888888888886 186801|Clostridia 1.0 S 0.6222222222222222 FAD dependent oxidoreductase 0.5111111111111111 - 0.8666666666666667 - 1.0 1.1.5.3 0.9777777777777777 ko:K00111 0.9777777777777777 ko00564,ko01110,map00564,map01110 0.9777777777777777 - 1.0 R00848 0.9777777777777777 RC00029 0.9777777777777777 ko00000,ko00001,ko01000 0.9777777777777777 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 0.9777777777777777 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001564_01807 0.022222222222222223 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 0.9777777777777777 0.9777777777777777 0.9777777777777777 0.9777777777777777 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 0.9777777777777777 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 0.9777777777777777 none 1.0 2401576 1266365 1429388 2392344 1774960 1423058 1360454 2947247 1928160 3103204 1909802 2520760 1789561 1932289 2728436 1619848 1979290 0 2369504 2605827 2539577 1483359 0 743628 2285591 1975988 2218994 0 1838952 3015369 550335 840699 860707 2334313 2437947 1819449 1931230 869933 846936 716117 436422 1403684 594579 559862 702248 1157479 760146 972603 615772 509455 821105 784500 830116 447613 551177 0 903491 1052190 602655 310838 0 727288 1165794 935490 860002 0 1032298 608632 869832 628964 396143 908257 1084805 783695 755104 402840 2201681 914203 693088 1662656 384933 437882 1050197 1651970 1349840 1687458 791389 1303867 1091984 1986366 2256533 1230124 1205406 0 2004279 2334613 1613649 839735 0 383028 1638130 2054443 2715905 0 1606645 1763230 367965 950063 1111516 2024941 1337505 1476573 1865620 655262 2313593 638470 749835 2514261 1407854 896558 1189441 2751272 2976516 1650582 1064940 1676101 1068618 3212921 3021141 1315642 2084206 0 2363517 2271729 2517100 578944 0 541751 3073915 2483787 3335196 0 815422 2692987 742828 1195137 821070 1668765 2553764 2016579 2933746 756900 4691390 3231672 5044061 1458245 2791827 4322983 3874662 2838806 5316878 6853824 3952403 5502816 1834583 7694496 7061430 3085901 5442718 0 4820897 3785805 4893928 3904322 0 3722044 7312979 6011097 5950727 0 3363452 3825513 3708348 1473786 5780895 6160526 4375824 6943599 7943615 4775290 +(Gln->pyro-Glu)QVITSFAGNR MGYG000002492_02355;MGYG000002517_00257 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_02355 0.5 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 565250 0 0 321512 0 0 449062 0 0 509056 0 0 312418 0 428386 0 276448 0 0 0 0 323463 401153 0 0 0 0 0 0 0 591056 0 211768 0 0 473680 0 0 0 0 0 0 0 0 0 0 307877 245707 0 0 0 0 0 0 0 0 0 0 0 0 376780 0 0 0 0 0 0 0 0 0 247716 0 0 239517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1742506 0 217909 0 0 0 943376 0 656962 0 1265912 0 0 0 0 0 852454 0 0 0 0 0 0 0 0 0 1109737 0 0 0 0 0 2382797 0 0 1813720 0 0 3288493 0 2091224 2130747 0 0 3252388 0 2843471 0 2143465 0 0 2304573 0 1815464 4099031 0 0 0 0 0 0 0 2056254 0 3877942 0 0 2597780 +(Gln->pyro-Glu)QVKM(Oxidation)RLAMEAIVAK MGYG000001157_00290;MGYG000003921_01842 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001157_00290 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237767 0 0 0 0 144817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1411258 0 0 0 0 0 0 0 0 0 931261 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVLANEPVTVEK MGYG000002281_01027;MGYG000002549_03571;MGYG000000196_00200;MGYG000000013_00186;MGYG000003351_01202;MGYG000002478_00234;MGYG000004797_03276 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0136@1|root,COG0136@2|Bacteria,4NE4V@976|Bacteroidetes,2FMHI@200643|Bacteroidia,4AKEU@815|Bacteroidaceae 0.7142857142857143 976|Bacteroidetes 1.0 E 1.0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate 1.0 asd 1.0 - 1.0 1.2.1.11 1.0 ko:K00133 1.0 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00017,M00018,M00033,M00525,M00526,M00527 1.0 R02291 1.0 RC00684 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Semialdhyde_dh,Semialdhyde_dhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_01027 0.14285714285714285 aspartate-semialdehyde dehydrogenase. L-aspartate-beta-semialdehyde dehydrogenase. - L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Monobactam biosynthesis|Cysteine and methionine metabolism|Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00133:asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 804623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242660 0 0 0 0 0 0 0 0 0 0 495937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255313 0 0 0 0 0 0 0 0 0 0 312999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVLEEIPR MGYG000000179_00905;MGYG000004087_00017;MGYG000001311_05164;MGYG000002946_01793 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,21YF6@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_00905 0.25 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204165 0 0 0 0 0 0 0 0 0 0 0 0 151334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226479 0 0 176094 0 0 0 0 0 0 0 0 0 71082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115862 0 0 161956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464765 0 0 718335 0 0 0 0 0 0 0 710582 0 +(Gln->pyro-Glu)QVLESLAPR MGYG000002545_01228;MGYG000003291_00547;MGYG000001300_00027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3WGQS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9,2.7.9.2 1.0 ko:K01007,ko:K08483 1.0 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060 1.0 M00173,M00374 1.0 R00199 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002545_01228 0.3333333333333333 phosphoenolpyruvate--protein phosphotransferase. | pyruvate, water dikinase. sugar--PEP phosphotransferase enzyme I. | pyruvate,water dikinase. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. | ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Phosphotransferase system (PTS) 1.0 K01007:pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2]|K08483:ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78288 0 0 295890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 871531 0 0 918823 0 0 0 0 813546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVLGTHVEQK MGYG000003693_01656;MGYG000002560_02698;MGYG000001789_00344;MGYG000002478_02005;MGYG000000243_02626 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0013@1|root,COG0013@2|Bacteria,4NFHW@976|Bacteroidetes,2FN1R@200643|Bacteroidia,4AMS5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_01656 0.2 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01872:AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7] 1.0 none 1.0 0 0 992023 0 843871 0 0 0 0 0 0 0 1175573 0 0 1160216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1067942 0 0 0 0 1109552 0 0 493893 0 505058 0 0 0 0 0 0 0 701901 0 0 236938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507305 0 0 0 0 527858 0 0 572649 0 738164 0 0 0 0 0 0 0 1025554 0 0 859401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472039 0 0 0 0 727678 0 0 373076 0 295718 0 0 0 0 0 0 0 0 0 0 258685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260423 0 0 289871 0 728468 0 0 0 0 0 0 0 1014236 0 0 887442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131923 0 0 0 0 373261 +(Gln->pyro-Glu)QVLKDDR MGYG000003683_01127 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4D10I@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit 1.0 rplX 1.0 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02895 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KOW,ribosomal_L24 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01127 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02895:RP-L24, MRPL24, rplX; large subunit ribosomal protein L24 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2046273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVLNQHPEVFDPR MGYG000000164_02284 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZPJ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG0191 Fructose tagatose bisphosphate aldolase 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_02284 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 935378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVM(Oxidation)AQLGLK MGYG000000031_02924;MGYG000000252_02294;MGYG000002966_00348;MGYG000002298_02773;MGYG000004733_01681;MGYG000000171_01273;MGYG000000142_01607;MGYG000000806_00435;MGYG000002298_00038 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3XZRB@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 0.6666666666666666 - 0.6666666666666666 - 1.0 4.1.2.17 1.0 ko:K01628 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R02262 1.0 RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_02924 0.1111111111111111 L-fuculose-phosphate aldolase. L-fuculose-1-phosphate lactaldehyde-lyase. - L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01628:fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVMAQLGLK MGYG000000031_02924;MGYG000000252_02294;MGYG000002966_00348;MGYG000002298_02773;MGYG000004733_01681;MGYG000000171_01273;MGYG000000142_01607;MGYG000000806_00435;MGYG000002298_00038 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3XZRB@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 0.6666666666666666 - 0.6666666666666666 - 1.0 4.1.2.17 1.0 ko:K01628 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R02262 1.0 RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_02924 0.1111111111111111 L-fuculose-phosphate aldolase. L-fuculose-1-phosphate lactaldehyde-lyase. - L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01628:fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] 1.0 none 1.0 0 0 114180 0 0 0 0 0 0 0 354297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169091 0 0 0 0 0 0 0 88910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337532 0 0 0 0 0 0 0 366716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692839 0 0 0 0 341034 +(Gln->pyro-Glu)QVMAQLGMK MGYG000001338_00134;MGYG000000200_00392;MGYG000000133_00165;MGYG000000212_01008;MGYG000000301_01359 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3WHFE@541000|Ruminococcaceae 0.6 186801|Clostridia 1.0 G 1.0 L-fuculose phosphate aldolase 0.6 fucA 0.6 - 1.0 4.1.2.17 1.0 ko:K01628 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R02262 1.0 RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_00134 0.2 L-fuculose-phosphate aldolase. L-fuculose-1-phosphate lactaldehyde-lyase. - L-fuculose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01628:fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17] 1.0 none 1.0 157739 106396 328429 163315 0 0 0 77766 0 196002 98607 0 168618 236469 91675 154826 121881 0 0 0 0 0 0 0 0 0 109851 0 299624 0 0 175803 112699 0 0 0 0 234943 146686 222392 80754 102591 0 0 232707 104965 0 0 66257 0 79580 92227 79580 0 107395 0 0 0 0 0 0 0 0 75861 194619 0 161155 0 258783 86782 0 0 0 0 64602 0 85989 391692 212934 0 0 0 0 60447 84222 192326 108551 0 0 114196 203570 278171 308276 0 0 0 0 0 0 0 0 339326 194780 0 112889 0 0 329123 356257 0 0 0 106602 196809 0 0 0 0 0 0 0 57482 0 123544 0 0 0 0 93185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92511 0 0 0 0 0 0 778226 845529 739364 1043301 0 0 903272 610164 537145 1052973 1068153 0 757462 1069183 801501 624443 823860 0 0 0 0 0 0 0 0 728503 855793 0 1123767 0 727940 1035535 1237575 0 0 759070 666643 740196 +(Gln->pyro-Glu)QVMIIYAATNK MGYG000002517_03148 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000002517_03148 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218032 0 0 0 0 358125 +(Gln->pyro-Glu)QVNIPSYLVK MGYG000002989_00885;MGYG000000389_02466;MGYG000003695_00624;MGYG000000249_01525;MGYG000002202_01331;MGYG000000271_01088;MGYG000000206_01061;MGYG000001374_01170;MGYG000001698_04057;MGYG000002517_02847;MGYG000004271_00043;MGYG000000404_01611;MGYG000003335_01405;MGYG000004842_00283;MGYG000004296_00416;MGYG000001310_00114;MGYG000002145_00311 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia 0.4117647058823529 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 - 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002989_00885 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 115841 0 0 141698 184328 394145 0 0 0 109538 0 106661 0 0 0 0 0 0 0 354424 0 147397 0 0 325987 0 0 0 0 0 88662 0 225224 0 0 96602 0 0 86444 0 0 99898 192211 173138 0 0 0 68844 0 125033 0 0 0 0 0 0 0 113237 0 0 0 0 211051 0 0 0 0 0 78205 0 107323 0 0 88241 0 0 184821 0 0 215716 100865 108246 0 0 0 187845 0 283100 0 0 0 0 0 0 0 153797 0 0 0 0 142475 0 0 0 0 0 91966 0 250488 0 0 189763 0 0 147859 0 0 256888 331702 684443 0 0 0 283268 0 739879 0 0 0 0 0 0 0 0 0 77399 0 0 587555 0 0 0 0 0 191546 0 729105 0 0 162351 0 0 921592 0 0 649775 848654 629144 0 0 0 956677 0 983762 0 0 0 0 0 0 0 696336 0 529161 0 0 685595 0 0 0 0 0 729224 0 653734 0 0 649083 +(Gln->pyro-Glu)QVNVPR MGYG000000042_01421;MGYG000004757_00594;MGYG000004464_00178;MGYG000000138_00665;MGYG000002603_01782;MGYG000001630_01142;MGYG000004848_00666;MGYG000003353_00058;MGYG000000074_01773;MGYG000003460_01161;MGYG000000215_00564;MGYG000001925_01419;MGYG000000273_00431;MGYG000004763_01689;MGYG000003681_02037;MGYG000003202_00129;MGYG000001503_00139;MGYG000002281_02290;MGYG000000357_02040;MGYG000001770_01653;MGYG000003546_00955;MGYG000003992_01709;MGYG000003446_00658;MGYG000001552_00984;MGYG000001313_00097;MGYG000004629_00424;MGYG000000013_02251;MGYG000003542_01415;MGYG000003691_01713;MGYG000003697_01485;MGYG000000348_00283;MGYG000001655_02933;MGYG000000044_01721;MGYG000001360_01239;MGYG000002834_01866;MGYG000003152_01866;MGYG000002930_00867;MGYG000000196_03974;MGYG000004588_00463;MGYG000002905_00001;MGYG000001661_02666;MGYG000003374_00521;MGYG000002762_01733;MGYG000003424_00456;MGYG000001789_00154;MGYG000000054_03933;MGYG000002293_00521;MGYG000003701_03123;MGYG000000098_02017;MGYG000002291_02272;MGYG000002080_00527;MGYG000004474_01617;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000001346_01533;MGYG000000243_01988;MGYG000001562_01075;MGYG000002540_03367;MGYG000001763_00317;MGYG000000254_02569;MGYG000003279_00951;MGYG000003812_01875;MGYG000003497_00215;MGYG000004754_01565;MGYG000000414_00662;MGYG000002418_00753;MGYG000000117_01463;MGYG000003535_00219;MGYG000000168_03211;MGYG000000673_00997 class d__Bacteria|p__Bacteroidota|c__Bacteroidia 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.39436619718309857 976|Bacteroidetes 0.971830985915493 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.971830985915493 tuf 1.0 - 0.971830985915493 - 1.0 ko:K02358 0.971830985915493 - 0.971830985915493 - 0.971830985915493 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.971830985915493 - 0.971830985915493 - 1.0 - 0.971830985915493 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.014084507042253521 - - - - 1.0 1.0 1.0 1.0 - 0.971830985915493 K02358:tuf, TUFM; elongation factor Tu 0.971830985915493 none 1.0 751499 1024103 1048639 487577 1472008 1045506 881565 965148 878681 740305 970212 916482 1501235 1108720 1312777 1238999 844781 443837 494645 946482 1913328 1484127 1318428 1688836 1074170 1521102 1151174 1054209 781460 1281710 1458691 1234282 1659225 1022366 1471014 1286017 1387236 1462623 1876267 903699 2007349 1236498 1841979 1286056 1257939 1942945 1858714 2434787 0 1601121 1713426 1531085 2876178 2908041 770852 1936067 1978172 1931669 2487501 1506483 1599604 786964 1718665 1699741 1291153 1490649 924479 1334884 407656 265992 2247769 1620938 2506357 1484905 1682476 2626886 1227503 397605 451078 1093146 1771157 1085624 1461070 1396383 1154373 1288849 2141694 971250 1377880 1414084 996610 1530167 1765065 2391690 1077191 954815 1457560 1118362 1995621 2098019 1171994 1398100 1119482 1458548 1645019 1686367 1596500 1442114 1335513 1228380 1272136 1315740 1111231 959884 1191576 1501301 618674 1012321 1687733 1959301 1008837 1071957 936434 1187353 2180883 1888127 1894053 1173436 1481567 1756867 671911 1681745 1097311 1064102 1199567 1780428 2386291 1810214 804263 888290 1098260 303324 1086827 1437473 1606871 1945259 2370837 1464702 1477168 1716364 1616503 1771243 1786630 1529089 1614397 1435332 4213135 2417068 1782380 1819786 2005209 1640386 2422776 2226271 1667951 602634 1616568 2761214 2312226 1935466 1924978 2349995 2118021 1826407 1373673 676758 773662 2526712 855501 1250149 1544432 2576608 1184134 2161096 563237 1061098 842888 699818 678271 1353368 +(Gln->pyro-Glu)QVNVPYIVVFMNK MGYG000000249_00026 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_00026 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2654912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVNYTVQTAC(Carbamidomethyl)HPLDVK MGYG000000224_00262;MGYG000003681_00233 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG3717@1|root,COG3717@2|Bacteria,4NDUV@976|Bacteroidetes,2FMP5@200643|Bacteroidia,4AM3B@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate 1.0 kduI 1.0 - 1.0 5.3.1.17 1.0 ko:K01815 1.0 ko00040,map00040 1.0 - 1.0 R04383 1.0 RC00541 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 KduI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000224_00262 0.5 5-dehydro-4-deoxy-D-glucuronate isomerase. 5-keto-4-deoxyuronate isomerase. The enzyme is involved in the degradation of polygalacturonate, a later stage in the degradation of pectin by many microorganisms. 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions 1.0 K01815:kduI; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [EC:5.3.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 859960 1087585 0 742716 0 1110952 1377242 1181482 0 1069599 0 1334771 0 0 0 0 0 917559 0 994548 0 730272 0 0 0 0 0 0 0 0 496484 0 0 0 0 856729 0 0 0 0 0 0 0 0 0 0 0 309524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721688 794337 400197 0 0 0 1052002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641183 0 0 530008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVPDSTEIRVDKVTGTLIR MGYG000000223_02386 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,3VPI5@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_02386 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 669382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 357764 0 375674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 734979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVPDTAEIKIDPVTNTLIR MGYG000001714_01486 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus_A|s__Coprococcus_A catus|m__MGYG000001714 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27M97@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF,SSF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001714_01486 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 323369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVPDTKGGVK MGYG000001637_02230;MGYG000000087_01268;MGYG000001367_03001;MGYG000001615_04300;MGYG000002141_01824;MGYG000000255_01557;MGYG000000489_01026;MGYG000001617_02046;MGYG000000077_02468;MGYG000004719_02002;MGYG000000997_00555;MGYG000001777_01059;MGYG000000312_02426;MGYG000002445_02276;MGYG000002528_02668;MGYG000003702_03102;MGYG000004359_01906;MGYG000000028_00944;MGYG000000271_02101;MGYG000000404_01798;MGYG000000398_00614;MGYG000002492_00660;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000003486_02521;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.48148148148148145 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.48148148148148145 etfB 1.0 - 0.9259259259259259 - 0.8148148148148148 ko:K03521 0.8148148148148148 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.8148148148148148 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.037037037037037035 - - - - 0.8148148148148148 0.8148148148148148 0.8148148148148148 0.8148148148148148 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.8148148148148148 none 1.0 925004 1112499 1389993 0 0 1614750 0 0 746091 1645543 0 1268502 2073980 1476889 0 0 0 0 1179419 0 0 1644508 0 596586 0 1169130 0 0 0 0 383488 0 929416 0 0 0 1034783 1257362 0 208847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220815 0 676524 3115953 1624096 0 0 937960 0 0 452712 675961 0 589632 1827023 658831 0 0 0 0 1623773 0 0 1858610 0 198187 0 780206 0 0 0 0 266828 0 1596150 0 0 0 483779 1007640 2765880 1875036 1833749 0 0 2484423 0 0 3591365 3922992 0 1628365 1141239 3804883 0 0 0 0 3773419 0 0 1370895 0 937078 0 2619275 0 0 0 0 1417476 0 2080444 0 0 0 3746932 2158300 310722 382051 1375016 0 0 1035045 0 0 603448 1394750 0 1281376 419590 855467 0 0 0 0 437238 0 0 411102 0 389155 0 799293 0 0 0 0 801587 0 1196209 0 0 0 2023243 1306877 +(Gln->pyro-Glu)QVPDTKGGVKFNPDGTLDR MGYG000001637_02230;MGYG000000271_02101;MGYG000000404_01798;MGYG000001777_01059;MGYG000000312_02426;MGYG000000154_01281;MGYG000002517_00543;MGYG000001319_02234;MGYG000002528_02668;MGYG000003702_03102 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.7 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.7 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVPDTKGGVQFNPDGTLNR MGYG000000164_00687;MGYG000004055_00051;MGYG000000127_04021;MGYG000001315_01867 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.75 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.75 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_00687 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVPDTNEIKVDPVTHTLVR MGYG000000262_01290 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF,SSF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_01290 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830589 0 0 0 0 335837 +(Gln->pyro-Glu)QVPDTSGKVAVNPDGTLNR MGYG000003589_02741;MGYG000002086_01704;MGYG000002057_00750 phylum d__Bacteria|p__Firmicutes_A 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,2N6RS@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003589_02741 0.3333333333333333 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit|K22431:carD; caffeyl-CoA reductase-Etf complex subunit CarD [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVPDTSGKVSVKPDGTLDR MGYG000001300_00292 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WH8V@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00292 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit|K22431:carD; caffeyl-CoA reductase-Etf complex subunit CarD [EC:1.3.1.108] 1.0 none 1.0 0 0 1231097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 964742 0 0 0 0 796600 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVPDTSGVVAVKEDGTMDR MGYG000000099_01611 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,26915@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_01611 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit|K22431:carD; caffeyl-CoA reductase-Etf complex subunit CarD [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496477 0 0 0 0 0 0 683210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 512198 602730 0 0 0 0 0 0 0 0 0 503812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVPDTTEIKLDPVTGTLIR MGYG000004893_01403;MGYG000002485_00624;MGYG000004828_00743 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG2086@1|root,COG2086@2|Bacteria,378IK@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004893_01403 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 778648 1426817 0 768714 2083907 785854 0 0 2148360 1814568 947710 1307979 523484 0 1898385 1190178 0 812275 0 692946 2145199 0 1526026 0 0 648426 0 0 1249833 1418805 869302 1491081 0 0 0 0 1194304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVPVMIHR MGYG000003372_03922;MGYG000002494_00951 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0441@1|root,COG0441@2|Bacteria,1MUP2@1224|Proteobacteria,1RMYE@1236|Gammaproteobacteria,3XNZY@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 GO:0000166,GO:0000900,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004812,GO:0004829,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006435,GO:0006446,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0017076,GO:0017148,GO:0019222,GO:0019538,GO:0019752,GO:0030371,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032553,GO:0032555,GO:0032559,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045182,GO:0045947,GO:0046483,GO:0046872,GO:0046914,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0097367,GO:0106074,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iPC815.YPO2433,iSDY_1059.SDY_1814 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000003372_03922 0.5 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01868:TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3] 1.0 none 1.0 0 0 0 0 0 2863876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1611339 0 1453018 0 0 0 0 3016659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1349402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1119703 0 869942 0 0 0 0 1049977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1004764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4721662 0 509562 0 0 0 0 3629867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9796568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15117400 0 3906881 0 0 0 0 133076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVQHLVKVEE MGYG000000184_01190;MGYG000001338_02789;MGYG000000301_00178;MGYG000000133_00063;MGYG000000200_01095;MGYG000000213_00196 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,3Y0NM@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein L30p/L7e 1.0 rpmD 1.0 - 1.0 - 1.0 ko:K02907 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L30 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_01190 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02907:RP-L30, MRPL30, rpmD; large subunit ribosomal protein L30 1.0 none 1.0 720772 523771 0 0 0 418799 0 0 0 1362788 977033 0 0 0 0 304891 0 0 0 0 653559 0 0 663769 0 0 684805 0 0 393757 0 0 0 0 433007 0 861828 0 0 0 0 0 0 0 0 0 0 0 184092 0 0 0 0 329856 0 0 0 0 0 0 0 0 0 0 0 0 0 462285 0 0 0 0 298277 0 0 0 0 1131476 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563116 670829 0 0 0 0 0 0 0 896043 0 0 0 0 0 0 0 0 413326 341383 0 422414 0 542932 520900 0 0 322559 0 0 0 418548 0 0 606404 0 265243 0 0 0 0 0 0 0 508073 0 0 331785 0 0 0 0 0 0 349501 568003 3944881 2833091 3323111 4988933 0 3020998 4486436 0 0 4564720 2485073 0 2169736 3736110 3649869 2871022 3949075 0 3400033 0 3828432 1811009 0 3358498 0 3417499 3371328 0 0 1694717 0 0 3239885 4924453 2650692 0 2921977 2828121 +(Gln->pyro-Glu)QVQTGDKFVVR MGYG000002560_04324 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp902388365|m__MGYG000002560 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002560_04324 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 9378810 0 0 0 0 5469452 0 0 0 0 0 0 0 7073532 0 0 0 0 4665487 0 0 0 0 5974499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1761462 0 0 0 0 0 0 0 1061847 0 0 0 0 1025795 0 0 0 0 2042747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314652 0 0 0 0 194672 0 0 0 0 0 0 0 458561 0 0 0 0 0 0 0 0 0 759831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 549842 0 0 0 0 0 0 0 0 0 306446 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVRPGLC(Carbamidomethyl)K MGYG000001338_03091;MGYG000000002_03130;MGYG000002312_00094;MGYG000000038_02498;MGYG000000251_02538;MGYG000000146_03079;MGYG000000262_02904;MGYG000000249_02227;MGYG000000195_00356;MGYG000002212_01534;MGYG000002772_00865;MGYG000000200_01731;MGYG000002040_00491;MGYG000001315_01504 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia 0.7857142857142857 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 0.7857142857142857 pgcA 1.0 - 1.0 5.4.2.2,5.4.2.8 1.0 ko:K01835,ko:K01840 1.0 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00114,M00549 1.0 R00959,R01057,R01818,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001338_03091 0.07142857142857142 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). | phosphomannomutase. phosphoglucose mutase. | phosphomannose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. | alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. | alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2]|K01840:manB; phosphomannomutase [EC:5.4.2.8] 1.0 none 1.0 0 1436736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1718812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2126479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2149714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVSAVKEAK MGYG000000243_01586 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0AS@200643|Bacteroidia,4AMX1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MbeB_N,TPR_1,TPR_11,TPR_16,TPR_17,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01586 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 2041257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1576212 0 0 0 0 1990524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVSPGVLALR MGYG000000255_00876;MGYG000000233_02977 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG1775@1|root,COG1775@2|Bacteria,1TS7H@1239|Firmicutes,2493U@186801|Clostridia,21YHW@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 2-hydroxyglutaryl-CoA dehydratase, D-component 1.0 fldB 1.0 - 1.0 1.3.7.8,4.2.1.167 1.0 ko:K04113,ko:K20903 1.0 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 1.0 M00541 1.0 R02451 1.0 RC00002,RC01839 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HGD-D 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_00876 0.5 benzoyl-CoA reductase. | (R)-2-hydroxyglutaryl-CoA dehydratase. - Inactive toward aromatic acids that are not CoA esters but will also catalyze the reaction: NH3 + acceptor + 2 ADP + 2 phosphate = hydroxylamine + reduced acceptor + 2 ATP + H2O.-!-In the presence of reduced acceptor, but in the absence of oxidizable substrate, the enzyme catalyzes the hydrolysis of ATP to ADP plus phosphate.-!-Formerly EC 1.3.99.15. | The enzymes from the bacteria Acidaminococcus fermentans and Clostridium symbiosum are involved in the fermentation of L-glutamate.-!-The enzyme contains [4Fe-4S] clusters, FMNH2 and riboflavin.-!-It must be activated by a an activator protein.-!-Once activated, it can catalyze many turnovers. 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized 2[4Fe-4S]- [ferredoxin] + 2 phosphate = 2 ATP + benzoyl-CoA + 2 H2O + reduced 2[4Fe- 4S]-[ferredoxin]. | (R)-2-hydroxyglutaryl-CoA = (2E)-glutaconyl-CoA + H2O. 1.0 1.0 1.0 1.0 Benzoate degradation|Metabolic pathways|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04113:bcrB, badE; benzoyl-CoA reductase subunit B [EC:1.3.7.8]|K20903:hgdA; (R)-2-hydroxyglutaryl-CoA dehydratase subunit alpha [EC:4.2.1.167] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 201209 552006 0 0 0 0 0 0 0 362333 252273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220701 0 340723 0 0 186223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127727 0 0 0 +(Gln->pyro-Glu)QVSVYPR MGYG000001065_00187;MGYG000000909_01199;MGYG000001311_00863;MGYG000001954_01693;MGYG000003366_00085;MGYG000003074_02174;MGYG000001531_02379;MGYG000000179_02646;MGYG000001367_01068;MGYG000000172_00061;MGYG000004691_02150;MGYG000001617_02395;MGYG000000198_03197 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,220IA@1506553|Lachnoclostridium 0.6923076923076923 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL27 family 0.6923076923076923 rpmA 0.7692307692307693 - 1.0 - 1.0 ko:K02899 0.7692307692307693 ko03010,map03010 0.7692307692307693 M00178 0.7692307692307693 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.7692307692307693 - 1.0 - 1.0 - 1.0 Ribosomal_L27 0.7692307692307693 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001065_00187 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.7692307692307693 K02899:RP-L27, MRPL27, rpmA; large subunit ribosomal protein L27 0.7692307692307693 none 1.0 183142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170395 0 0 0 0 0 0 0 0 0 0 0 0 93320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294567 0 406999 0 0 0 0 0 0 387340 0 0 0 0 0 0 0 0 0 0 508395 0 +(Gln->pyro-Glu)QVTDGPAAENAK MGYG000000074_01070 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG0457@2|Bacteria,4PESY@976|Bacteroidetes,2G21B@200643|Bacteroidia,22UIH@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01070 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 624221 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVTEKAEK MGYG000002478_04136;MGYG000002549_02639;MGYG000004899_02720;MGYG000001378_01963;MGYG000000236_03832;MGYG000000196_03151;MGYG000001346_01418 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002478_04136 0.14285714285714285 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2] 1.0 none 1.0 0 0 1281214 0 1388561 1044643 0 0 0 1198136 0 0 0 0 0 0 0 0 0 0 0 1165903 0 1207375 0 0 0 0 0 1359427 0 0 1678284 0 0 0 0 901977 0 0 936627 0 994268 632068 0 0 0 947097 0 0 0 0 0 0 0 0 0 0 0 750761 0 566496 0 0 0 0 0 480998 0 0 522695 0 0 0 0 351754 0 0 1005521 0 988228 1101321 0 0 0 742520 0 0 0 0 0 0 0 0 0 0 0 604502 0 745988 0 0 0 0 0 473855 0 0 552004 0 0 0 0 599561 0 0 863334 0 662294 617727 0 0 0 662729 0 0 0 0 0 0 0 0 0 0 0 427674 0 452310 0 0 0 0 0 635605 0 0 613232 0 0 0 0 534546 0 0 469395 0 571459 509572 0 0 0 401717 0 0 0 0 0 0 0 0 0 0 0 259218 0 646377 0 0 0 0 0 247086 0 0 383532 0 0 0 0 665880 +(Gln->pyro-Glu)QVVDKTK MGYG000000074_01205 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,22U5S@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000074_01205 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272598 0 0 0 0 326296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164428 0 625975 0 604847 0 0 0 0 0 0 0 0 0 0 968930 0 +(Gln->pyro-Glu)QVVEEEVK MGYG000000179_03221 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24R6P@186801|Clostridia,220KI@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03221 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582839 0 628785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490593 0 0 0 0 0 0 0 0 0 0 460954 0 +(Gln->pyro-Glu)QVVIC(Carbamidomethyl)GSQYSGEIKK MGYG000000077_01765;MGYG000000262_01556 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,25VG1@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_01765 0.5 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 177742 0 372201 0 0 0 0 0 0 0 0 0 0 0 341577 0 0 0 0 0 0 0 0 0 0 0 279718 0 0 0 0 0 0 0 0 0 0 695331 0 0 0 0 0 0 0 0 0 0 0 373927 275691 0 0 0 351625 0 0 318513 0 0 0 0 0 0 265609 425041 0 0 0 0 0 0 1360665 0 435741 0 784990 0 729523 0 0 0 0 857466 0 0 0 996163 866851 0 932588 0 0 0 0 1035171 0 0 0 0 0 0 1020996 1080097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVVTAAADGAIAATQAEK MGYG000001315_00850 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,27IZT@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Pyridine nucleotide-disulphide oxidoreductase 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_00850 1.0 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 K00384:trxB, TRR; thioredoxin reductase (NADPH) [EC:1.8.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 497559 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 786533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVVTVAGDTK MGYG000001306_03308;MGYG000001783_02428 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_03308 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 387583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 979562 0 0 0 0 756903 0 0 0 0 1658239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 615689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVYAFGAGTKK MGYG000001367_03018;MGYG000000262_02240 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,220DE@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 1.0 Acetyl-CoA hydrolase/transferase C-terminal domain 0.5 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001367_03018 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 588500 0 0 0 623815 0 627225 0 0 0 0 0 0 0 0 0 0 0 0 0 717673 0 360540 0 0 0 0 0 0 0 0 0 353608 367982 0 0 0 0 353768 0 0 0 0 0 270254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386970 0 0 0 0 0 0 0 0 0 318762 571194 0 0 0 0 1531558 0 0 0 713248 0 1102594 0 0 0 0 0 0 0 0 0 0 0 0 0 1289403 0 291662 0 0 0 0 0 0 0 0 0 1447077 1243606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397100 0 0 0 726582 0 482465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 978790 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVYAFGAGTQK MGYG000003937_01094;MGYG000002272_01500;MGYG000001300_00298;MGYG000003166_01331;MGYG000002641_00051;MGYG000000022_01327;MGYG000002040_01712;MGYG000002545_00551;MGYG000002619_02242;MGYG000003899_01139 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,3WGGE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acetyl-CoA hydrolase/transferase C-terminal domain 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01094 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1108998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1224038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVYGFGAGTKK MGYG000000271_00943;MGYG000004414_01832;MGYG000004271_01186 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Acetyl-CoA hydrolase transferase 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00943 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 1566136 0 0 0 0 0 0 0 0 0 0 0 2369087 0 0 0 0 2342900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 979969 0 0 0 0 1045686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 542761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1062894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 892083 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVYGNANLYNK MGYG000002494_04543;MGYG000002506_02163;MGYG000002515_00391 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1652@1|root,COG1652@2|Bacteria,1RD8K@1224|Proteobacteria,1S4CB@1236|Gammaproteobacteria,3XPJS@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 1.0 S 1.0 response to potassium ion 0.6666666666666666 ygaU 1.0 GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BON,LysM 1.0 - 1.0 - 1.0 CBM50 1.0 - 0.6666666666666666 MGYG000002494_04543 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 462259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379175 0 571024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1241919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1182172 0 841225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QVYVLTKDEGGR MGYG000001615_01716;MGYG000000171_02844;MGYG000002279_01932;MGYG000001673_01975;MGYG000000201_03875;MGYG000000245_03248;MGYG000001688_04229;MGYG000000930_01271;MGYG000000280_01200;MGYG000002926_00232;MGYG000001714_01291;MGYG000000198_01165;MGYG000000392_00966;MGYG000000271_03365;MGYG000001315_01207;MGYG000000133_02991;MGYG000004879_01608;MGYG000003273_00234;MGYG000000140_01590;MGYG000001065_02730;MGYG000002994_01317;MGYG000002528_01098;MGYG000000263_00836;MGYG000003899_01642;MGYG000000179_00920;MGYG000000216_02406;MGYG000001563_01273;MGYG000002980_01277;MGYG000002517_00205;MGYG000001531_00906;MGYG000004296_01668;MGYG000001607_01045;MGYG000001141_02439;MGYG000001809_00576;MGYG000001652_01300;MGYG000000127_03982;MGYG000003425_03741;MGYG000000258_00266;MGYG000000251_00064;MGYG000001338_03373;MGYG000002670_00364;MGYG000001300_00280;MGYG000000233_00807;MGYG000000142_00171;MGYG000002702_01978;MGYG000000255_02009;MGYG000002040_01212;MGYG000004087_00551;MGYG000000242_00282;MGYG000002143_01659;MGYG000003266_00955;MGYG000002417_01244;MGYG000000164_01096;MGYG000002794_01318;MGYG000000187_02029;MGYG000000202_03457;MGYG000000212_03313;MGYG000001698_04050;MGYG000003074_01359;MGYG000001777_01732;MGYG000002212_00196;MGYG000000249_00026;MGYG000004799_01385;MGYG000002136_02858;MGYG000004630_01824;MGYG000000262_00030;MGYG000003486_01055;MGYG000002772_01895;MGYG000002492_00344;MGYG000001617_01406;MGYG000002057_01066;MGYG000002052_00232;MGYG000004475_00887;MGYG000001086_01249;MGYG000000206_00901 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.21333333333333335 186801|Clostridia 0.9733333333333334 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001615_01716 0.013333333333333334 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 936182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2005113 0 0 0 0 0 0 0 0 0 0 0 0 0 1679268 0 0 0 0 1175175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1668469 0 1470358 0 0 0 0 0 0 0 0 1825600 0 0 1493465 0 0 0 1902755 0 0 0 0 0 0 1416832 0 0 0 1762801 0 0 1835003 0 0 0 1569919 1515233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QWDKGQQVIFEANPDYYGEEPK MGYG000000133_03036 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_03036 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 651552 932475 0 0 0 0 0 0 0 639889 0 1107477 771454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1240416 0 0 0 0 463657 +(Gln->pyro-Glu)QWGFENVHC(Carbamidomethyl)VPEQMVK MGYG000000243_01121 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000243_01121 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QWGFENVHTVPEQMVK MGYG000002478_04136 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002478_04136 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2] 1.0 none 1.0 322402 533191 0 393353 595488 0 0 0 647003 0 0 0 490185 326808 0 488752 0 382154 330085 308789 0 0 584086 0 0 288499 753334 0 532381 544041 0 615733 350462 0 559905 0 401929 369460 458068 549817 467603 659794 684919 0 0 836526 493255 0 0 679483 710019 713961 0 618855 0 0 740867 615191 0 0 786458 0 0 789758 754258 754115 638437 583744 0 612395 515304 357859 615721 0 586786 392716 545591 997507 415952 651078 461559 0 0 307276 390257 0 0 618307 0 329403 0 0 0 0 700846 339769 0 0 731919 0 0 0 547481 615587 373023 246745 0 0 329791 819175 0 0 485824 314103 0 0 0 325284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402947 606027 0 0 484417 423240 0 0 143575 401367 291652 0 205545 0 1119371 306466 800198 0 0 1130853 0 0 572942 402934 1361420 528544 493343 0 0 353833 666046 820702 0 423560 460620 +(Gln->pyro-Glu)QWGSPTPGHPEVDIMR MGYG000001306_00741;MGYG000002560_01049;MGYG000002549_01292;MGYG000001378_04775;MGYG000000196_00739;MGYG000002478_02451;MGYG000001461_03636;MGYG000004797_01102 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia,4AKPQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Belongs to the transketolase family 1.0 tkt 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_00741 0.125 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 795907 0 764500 0 0 0 0 0 888927 0 817106 0 0 0 0 633596 0 0 0 0 744365 0 0 0 0 515324 0 0 0 0 510956 0 0 0 0 747082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330295 0 436596 0 0 0 0 0 364098 0 517646 0 0 0 0 777412 0 0 0 0 717558 0 0 0 0 753068 0 0 0 0 0 0 0 0 0 314611 +(Gln->pyro-Glu)QWGSVTPGHPELDLQR MGYG000002080_01068;MGYG000002293_00078;MGYG000003697_02025 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the transketolase family 1.0 tkt 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002080_01068 0.3333333333333333 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 584632 0 611105 556191 0 513460 0 0 611160 446509 464063 0 0 564592 426237 1683588 0 0 0 696192 2266181 527433 0 0 0 2030077 0 0 0 0 657965 484161 398409 0 0 599023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QWNHEQR MGYG000000003_02056;MGYG000003279_02071 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000003_02056 0.5 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 2559216 0 0 1796140 0 0 2196757 0 2313322 869844 0 0 0 2347225 1504545 0 0 0 3034621 2980260 0 0 0 0 1633717 2390804 0 0 0 0 0 0 0 0 0 2336452 1922586 0 157587 0 0 357162 0 0 412726 0 491910 264313 0 0 0 366458 112797 0 0 0 446743 141428 0 0 0 0 347629 287382 0 0 0 0 0 0 0 0 0 124264 265380 0 349219 0 0 0 0 0 153297 0 407393 149512 0 0 0 167070 0 0 0 0 333505 183400 0 0 0 0 476733 166042 0 0 0 0 0 0 0 0 0 401873 397136 0 0 0 0 181180 0 0 505827 0 175430 205619 0 0 0 185224 283059 0 0 0 552837 0 0 0 0 0 288542 321939 0 0 0 0 0 0 0 0 0 287376 0 0 0 0 0 90784 0 0 0 0 0 0 0 0 0 4031960 308444 0 0 0 0 0 0 0 0 0 178156 334370 0 0 0 0 0 0 0 0 0 0 164533 0 +(Gln->pyro-Glu)QWSVDFDGDGAHSDN(Deamidated)GR MGYG000002485_00658 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 2EYI9@1|root,33RS4@2|Bacteria,37BMK@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_00658 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2298319 0 0 0 0 0 0 574865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QWSVDFDGDGAHSDNGR MGYG000002485_00658 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 2EYI9@1|root,33RS4@2|Bacteria,37BMK@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_00658 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4860263 0 0 0 0 0 0 918720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QWTDMLQASK MGYG000000029_00388;MGYG000001345_03249;MGYG000003351_05247;MGYG000001378_04109;MGYG000000054_02624;MGYG000002549_04149;MGYG000003312_03104;MGYG000000013_01887;MGYG000004899_02709 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG2152@1|root,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,2FPFW@200643|Bacteroidia,4APF0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG NOG16664 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1080 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000029_00388 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 407600 0 0 359456 0 0 0 0 0 0 931390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168132 0 0 0 0 0 0 114054 0 191103 118342 0 287455 0 0 0 0 0 0 786496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305466 0 0 0 0 0 0 243050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 706176 240443 0 408278 0 0 0 0 0 0 488857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 200537 0 300353 0 0 0 0 165372 0 136504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QWTHGGVVFAPVPR MGYG000004271_00017;MGYG000000245_02639;MGYG000002517_02872;MGYG000000271_01062;MGYG000004719_01259 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00017 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513820 0 0 0 0 0 0 610657 0 0 0 0 0 0 0 0 0 0 0 933208 0 779324 0 0 0 0 0 0 0 0 0 0 0 0 0 442876 0 786383 901364 0 0 0 828909 0 0 1027084 0 0 0 0 0 0 0 0 0 0 0 1305784 0 1054768 0 0 0 0 0 0 0 0 0 0 0 0 0 940737 0 1117609 2243522 0 0 0 1304758 +(Gln->pyro-Glu)QYAAVLAVAK MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG3209@1|root,COG3209@2|Bacteria,1TRJ1@1239|Firmicutes,24AU6@186801|Clostridia,3WHF3@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 M 1.0 COG3209 Rhs family protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Big_2,Flg_new,Fn3_assoc,LRR_5,Lipase_3,N_methyl,Peptidase_M15_4,Transglut_core 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03072 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286295 0 0 0 0 0 0 +(Gln->pyro-Glu)QYAGFSTAEESNAFYR MGYG000002575_01112;MGYG000000029_00452;MGYG000003367_01505;MGYG000002205_01528;MGYG000002549_04227;MGYG000003449_01192;MGYG000001346_00857;MGYG000000053_01401;MGYG000002418_00781;MGYG000001370_02456;MGYG000004464_01736;MGYG000004658_00971;MGYG000000098_00635;MGYG000004769_01857;MGYG000003693_01258;MGYG000001412_02065;MGYG000000273_01824;MGYG000001783_00897;MGYG000001551_03344;MGYG000003279_00971;MGYG000000414_00242;MGYG000003908_01540;MGYG000004763_00641;MGYG000001345_03358;MGYG000000243_02184;MGYG000004158_00691;MGYG000004822_01122;MGYG000001378_04187;MGYG000002171_02052;MGYG000002007_01203;MGYG000000196_02288;MGYG000002113_00130;MGYG000004006_00254;MGYG000000254_00655;MGYG000003363_01960;MGYG000003542_00863;MGYG000003649_00955;MGYG000003469_00358;MGYG000004501_01751;MGYG000001306_00281;MGYG000003312_00926;MGYG000001925_02121;MGYG000000138_02196;MGYG000001806_01383;MGYG000002478_00340;MGYG000001415_00892;MGYG000001365_00414;MGYG000000442_00346;MGYG000000074_01524;MGYG000000054_02932;MGYG000000003_01875;MGYG000002438_02292;MGYG000003681_00140;MGYG000000236_01415 domain d__Bacteria 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,4AMCS@815|Bacteroidaceae 0.4444444444444444 976|Bacteroidetes 0.8703703703703703 I 1.0 Psort location Cytoplasmic, score 8.96 0.4444444444444444 mutB 0.9629629629629629 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002575_01112 0.018518518518518517 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428666 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYAGFSTAEESNAFYRR MGYG000002575_01112;MGYG000000029_00452;MGYG000003367_01505;MGYG000002205_01528;MGYG000002549_04227;MGYG000003449_01192;MGYG000001346_00857;MGYG000000053_01401;MGYG000002418_00781;MGYG000001370_02456;MGYG000004464_01736;MGYG000004658_00971;MGYG000000098_00635;MGYG000004769_01857;MGYG000001412_02065;MGYG000000273_01824;MGYG000001783_00897;MGYG000001551_03344;MGYG000003279_00971;MGYG000000414_00242;MGYG000003908_01540;MGYG000004763_00641;MGYG000001345_03358;MGYG000000243_02184;MGYG000004158_00691;MGYG000004822_01122;MGYG000001378_04187;MGYG000002171_02052;MGYG000002007_01203;MGYG000000196_02288;MGYG000002113_00130;MGYG000004006_00254;MGYG000000254_00655;MGYG000003363_01960;MGYG000003542_00863;MGYG000003469_00358;MGYG000003312_00926;MGYG000001925_02121;MGYG000000138_02196;MGYG000001806_01383;MGYG000002478_00340;MGYG000001415_00892;MGYG000001365_00414;MGYG000000442_00346;MGYG000000074_01524;MGYG000000054_02932;MGYG000000003_01875;MGYG000002438_02292;MGYG000003681_00140;MGYG000000236_01415 domain d__Bacteria 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,4AMCS@815|Bacteroidaceae 0.44 976|Bacteroidetes 0.88 I 1.0 Psort location Cytoplasmic, score 8.96 0.44 mutB 0.98 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002575_01112 0.02 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYANATLLR MGYG000002438_02632;MGYG000000196_04526;MGYG000000029_01860;MGYG000001345_00467;MGYG000000044_01913;MGYG000002033_00099;MGYG000002478_01776;MGYG000000138_02337;MGYG000001372_03000;MGYG000000243_02506;MGYG000001346_02842;MGYG000003221_00520;MGYG000003681_01109;MGYG000001313_02623;MGYG000000174_01424;MGYG000000236_00428;MGYG000001599_01342;MGYG000004797_01374;MGYG000002540_01909 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia 0.3157894736842105 976|Bacteroidetes 1.0 G 0.6842105263157895 Fructose-1,6-bisphosphate aldolase, class II 0.3157894736842105 fba 0.6842105263157895 - 1.0 4.1.2.13 0.6842105263157895 ko:K01624 0.6842105263157895 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6842105263157895 M00001,M00003,M00165,M00167,M00344,M00345 0.6842105263157895 R01068,R01070,R01829,R02568 0.6842105263157895 RC00438,RC00439,RC00603,RC00604 0.6842105263157895 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6842105263157895 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02632 0.05263157894736842 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6842105263157895 0.6842105263157895 0.6842105263157895 0.6842105263157895 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6842105263157895 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 0.6842105263157895 none 1.0 489493 951138 831031 765361 1037610 578073 1176048 694919 661553 717229 1174637 845326 1416679 597056 512344 1131807 585887 1138429 428090 441678 1202508 1017682 1526644 1042776 674505 724523 1214814 1179786 845827 984637 1140615 806813 1530823 731406 877951 948608 835493 1050520 1011349 846731 1177923 1270175 1868341 1147580 1186580 1246119 1217209 1487526 2001051 1526812 1861333 1347746 1144809 2453745 1119588 1056643 814416 0 1707318 1265537 2224929 815715 1210068 1247020 1235583 1668864 1122154 1475925 840747 726407 1178895 945170 0 0 913663 0 634968 1030371 1315912 589552 1704360 1053845 986859 714821 969214 508373 1271139 1317278 1075048 903158 707636 1251435 802987 2622058 700759 657937 941547 1214530 2795884 1525082 662342 0 653316 2873153 1014390 763272 1090424 994973 799310 429048 580060 1144547 614244 1008227 0 150612 0 0 0 0 213745 166616 0 0 232853 258947 487237 0 294016 235713 0 231007 0 223955 692893 179969 200574 0 0 319684 0 361053 0 187021 217152 154251 126445 389193 294717 310115 260492 0 741536 0 573412 612946 797108 1684739 1729250 1051384 1457992 928729 1448768 1483771 1190893 0 492121 1642119 1324461 2615340 731840 1252335 1828770 0 1862565 853823 857713 1061005 405343 2112342 0 2140903 981103 471132 443294 631780 0 565809 468913 1074352 +(Gln->pyro-Glu)QYANQTLLR MGYG000004468_00561;MGYG000002455_03337 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00561 0.5 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402865 0 0 0 0 329911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 612166 0 0 0 0 389275 0 0 0 0 239670 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYDDAIATFNK MGYG000002171_02152;MGYG000000243_01586;MGYG000002478_03786 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0AS@200643|Bacteroidia,4AMX1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MbeB_N,TPR_1,TPR_11,TPR_16,TPR_17,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_02152 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 766126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1063383 0 0 0 0 839510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265237 0 0 0 0 0 +(Gln->pyro-Glu)QYDDRYHVLK MGYG000000077_02468;MGYG000003074_00586;MGYG000002141_01824;MGYG000000312_02426;MGYG000000262_02235;MGYG000003702_03102 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 0.6666666666666666 etfB 1.0 - 0.6666666666666666 - 0.6666666666666666 ko:K03521 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.6666666666666666 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.16666666666666666 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.6666666666666666 none 1.0 920098 1648074 1166998 578286 1936908 1560717 214536 1640941 606312 1657757 880943 1522750 1975825 1019598 1650459 1641846 1082114 0 1241461 1170943 903873 2095595 0 545666 1436820 776529 679229 0 638879 931499 466521 1137126 880315 923455 1017339 0 499414 781854 1386070 1169784 459542 984527 591495 816952 1800311 969003 1074410 765290 501877 526946 897875 564227 854393 327512 554525 0 997717 1079044 857741 564924 0 1355619 1021057 964159 1020376 0 1600345 904988 1074935 791744 456237 1225438 1205425 0 1179543 621307 3412622 6315657 1048727 6859588 424114 3620232 941028 3782291 1161141 4416858 1440009 1865463 2988706 2421188 4266176 3435303 2975887 0 4186710 4055126 2664527 5496247 0 1527295 5707773 3438746 4937722 0 758171 2802096 957431 4062973 2708239 5152992 5202242 0 3048368 866803 1402598 2092701 1148356 2520284 1530933 2099985 1937185 1449639 1624369 2307471 1312021 978785 2231864 1676998 1556068 3343744 2463964 0 1159214 2158499 1364834 1787587 0 1587538 1592506 1057532 1978502 0 1592324 1525331 990612 1354216 1648134 1095134 1457451 0 857524 1405290 0 717583 1017121 0 574785 1127239 517423 414213 307130 228987 1333534 474166 724148 268883 255482 823052 333392 0 352182 0 338459 1323845 0 935597 458629 231118 412973 0 0 178728 1302348 1403345 1362014 355757 401053 0 59044 802633 +(Gln->pyro-Glu)QYDEFFHR MGYG000001300_01892 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1073@1|root,COG1073@2|Bacteria,1UQS2@1239|Firmicutes,24F94@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 alpha beta 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AXE1,Abhydrolase_1,Chlorophyllase2,Hydrolase_4,Peptidase_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_01892 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 539396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 676824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 785878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYEDEIKR MGYG000004479_01906;MGYG000001364_02120;MGYG000000042_01480;MGYG000003693_03030;MGYG000001306_00956 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2825@1|root,COG2825@2|Bacteria,4NWPA@976|Bacteroidetes,2G3DE@200643|Bacteroidia,4AWDW@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 M 1.0 Membrane 0.8 - 0.8 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004479_01906 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 417837 0 0 0 0 0 0 0 0 0 0 0 211852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 785085 0 0 0 0 0 0 976076 0 0 0 0 1697291 0 0 0 0 1241671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYEDELQNLK MGYG000000179_04961;MGYG000000198_05763;MGYG000000650_00893;MGYG000004087_02269;MGYG000001065_01413;MGYG000001311_03457;MGYG000001531_02630 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,21ZWZ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 K 1.0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides 1.0 greA 1.0 - 1.0 - 1.0 ko:K03624 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03021 1.0 - 1.0 - 1.0 - 1.0 GreA_GreB,GreA_GreB_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_04961 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03624:greA; transcription elongation factor GreA 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYEDEMKR MGYG000002478_01528;MGYG000002171_01839;MGYG000002560_00092;MGYG000000243_03119;MGYG000004797_03114 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2825@1|root,COG2825@2|Bacteria,4NSCM@976|Bacteroidetes,2FQ15@200643|Bacteroidia,4APWT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 ompH 1.0 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01528 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 0 0 2796049 1559014 2343546 1445369 0 1011086 1062649 0 984085 0 2819919 0 1198525 2906730 0 0 0 0 1323838 1254462 0 1368504 1118000 0 0 0 1116121 1364804 2011973 0 2775262 0 1535835 1068012 0 2591858 0 0 1018631 1027758 1213147 977729 0 1260467 844290 0 1051535 0 1782643 0 851779 1477619 0 0 0 0 879184 971326 0 570219 990737 0 0 0 899211 1116396 650903 0 880746 0 1119519 889891 0 734051 0 0 832807 550277 1069863 771719 0 473545 790483 0 540570 0 1813084 0 677518 1048390 0 0 0 0 543633 357373 0 853442 704846 0 0 0 686885 562719 964252 0 484332 0 744786 931777 0 693534 0 0 731979 370927 395846 465722 0 268688 529789 0 142138 0 237252 0 360285 0 0 0 0 0 133760 428258 0 356325 492753 0 0 0 288042 443106 325244 0 491504 0 264752 261001 0 521812 0 0 465610 392013 1130977 470314 0 480377 584132 0 324973 0 813519 0 583553 598764 0 0 0 0 260567 400092 0 441509 503860 0 0 0 803862 683019 470628 0 271368 0 280725 634445 0 566724 +(Gln->pyro-Glu)QYEDRYHEIK MGYG000000271_02101;MGYG000002517_00543;MGYG000000489_01026 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02101 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 160015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9893302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8806303 0 0 0 +(Gln->pyro-Glu)QYEDRYHELK MGYG000001637_02230;MGYG000004719_02002;MGYG000000997_00555;MGYG000000271_02101;MGYG000000404_01798;MGYG000002517_00543;MGYG000000489_01026 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 4697409 2962542 2524618 5348300 4904173 4396568 3835778 5871678 3661426 6546082 4531356 5482179 4316468 4973946 6037461 4263135 6322150 0 5740536 4544073 5428430 3001098 0 1925886 5592904 4035247 4811970 0 2505113 5332086 1625173 2281281 2289019 5944194 4475557 4632342 4768136 2011369 317973 190367 187508 206207 268048 294029 205374 256495 0 321811 321720 164879 242404 353678 73010 236014 295546 0 182642 87662 195065 214956 0 188971 258772 205924 192622 0 212509 184760 0 152669 124022 168523 118789 297153 0 247145 1134588 691823 291857 1410367 466445 334473 1332658 1529152 1624689 1747757 1105964 1327469 1876021 1837051 2230183 1448219 645821 0 2277578 2227428 1239267 497323 0 396881 2022225 2365733 2693411 0 1026836 1778883 218003 573573 555770 1353972 1018301 1317859 2584547 759719 13518484 3511045 3466330 12634788 8367114 5028658 7103395 21702823 19096620 9180113 5167916 9109985 4430314 20162213 20527384 5954889 11249408 0 14916442 12778682 9271234 1414218 0 689548 24471196 14465930 15479299 0 4135197 19597006 2970371 4520979 3694644 11150576 15924493 12158384 16496234 2639274 6906059 7599220 14246523 1674563 6315833 9741767 0 6874085 10720150 16538273 11616945 15292629 6500959 15525637 13067880 7416718 13038829 0 10155572 6004500 9705282 6590471 0 7655673 13453349 10205176 12365222 0 2932744 7551158 10470820 3712298 18008078 10759623 0 12224986 18916038 11753038 +(Gln->pyro-Glu)QYEDRYHELKAK MGYG000001637_02230;MGYG000000271_02101;MGYG000000404_01798;MGYG000002517_00543 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYEDRYHILK MGYG000002934_01790;MGYG000000028_00944;MGYG000002523_01027;MGYG000002528_02668 phylum d__Bacteria|p__Firmicutes_A 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.5 186801|Clostridia 0.75 C 1.0 electron transfer flavoprotein 0.5 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002934_01790 0.25 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 0 329398 224278 0 0 301538 0 0 0 0 0 55877 150928 0 137612 197784 0 0 0 234298 477872 491743 0 225923 251539 0 455466 0 536733 0 0 501640 306318 160513 0 0 0 216855 0 2023183 479972 0 0 693510 0 0 0 0 0 0 298306 0 0 280356 0 0 0 315545 0 591616 0 1297554 90550 0 179838 0 398925 0 0 916798 465155 0 0 0 0 446419 0 7208500 2044536 0 0 2508265 0 0 0 0 0 1695534 1365666 0 1396089 1822508 0 0 0 1154278 1562769 7394866 0 1913497 1417328 0 1391033 0 4426093 0 0 6275728 2974522 2747160 0 0 0 1845243 0 1093966 545902 0 0 392491 0 0 0 0 0 82804 474383 0 171347 206216 0 0 0 359733 233831 460183 0 510902 105839 0 392540 0 2809322 0 0 1173049 602136 0 0 0 0 499802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63879 +(Gln->pyro-Glu)QYEDRYHVVK MGYG000000080_01476;MGYG000002492_00660 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_01476 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 486699 281131 0 344900 0 0 0 0 0 0 0 155707 0 0 177231 0 316449 0 0 0 0 193354 0 0 0 0 158888 526372 0 0 0 207435 0 0 0 0 137953 0 314641 853831 0 794615 0 0 0 0 0 0 0 227524 0 0 267985 0 1338724 0 0 0 0 759739 0 0 0 0 1108256 357916 0 444719 0 612708 0 0 0 0 844444 0 1165813 5717752 0 1897960 0 0 0 0 0 0 0 2271357 0 0 2267946 0 595218 0 0 0 0 899525 0 0 0 0 1190253 1019042 0 1866193 0 4983354 0 0 0 0 4343446 0 0 264960 0 139933 0 0 0 0 0 0 0 944563 0 0 119259 0 404348 0 0 0 0 0 0 0 0 0 428953 0 0 84507 0 0 0 0 0 0 252182 0 0 218218 0 110651 0 0 0 0 0 0 0 168991 0 0 227785 0 0 0 0 0 0 0 0 0 0 0 194158 2915724 0 0 0 0 0 0 0 0 334025 +(Gln->pyro-Glu)QYEYHILK MGYG000001346_02437 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 2A8EE@1|root,30XG7@2|Bacteria,4NPA9@976|Bacteroidetes,2G2CC@200643|Bacteroidia,4ANGR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_02437 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1492685 0 0 0 0 1520509 0 0 0 0 1324903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809624 0 0 0 0 813157 0 0 0 0 749801 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYFAETDQTVNKR MGYG000001300_02036;MGYG000000022_00458;MGYG000002224_01508;MGYG000002610_00685;MGYG000000039_00979;MGYG000000589_00366 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02036 0.16666666666666666 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 959666 1406259 2093389 1240550 521099 1450351 805278 672877 1153299 1215247 905829 734526 1885342 1609451 1027386 1777944 1761009 1555157 2080053 1169915 0 1246081 795630 1074157 1233372 1098944 847152 1267800 0 658549 1515984 1380628 2322016 1283648 728299 968169 981699 2123465 1666862 2307671 2334906 1521238 1241892 1954885 2108496 735525 2438548 348017 1268836 1883406 1400633 1860382 1487714 1139263 1965463 803356 2651874 2060155 879197 1632728 1081619 1548821 2326943 1569669 1560106 1250401 256177 1509651 1894844 1605294 2433504 1584691 661255 1218534 1837583 1776344 359867 525368 466625 615890 491988 359391 432588 554486 759781 433010 584278 533548 557887 579018 319203 496654 0 1480942 359908 400688 528001 0 1673788 0 354051 0 0 1960234 0 613145 503596 373421 0 648869 0 289020 380169 394505 1234071 1466822 2289470 1254543 2011436 1585485 1959165 856218 1700285 1490555 1786398 2562754 2135884 1707443 1551039 1782592 1612474 1042628 2433733 1249994 1450809 1786703 2067586 1360619 2078336 1726055 1453054 1170387 767670 2183372 1982835 2035184 2401589 2456692 469789 1408306 1872792 2678921 0 280569 377081 0 0 340148 0 324663 301915 0 0 504923 201371 0 0 0 0 1211451 0 0 0 0 1351115 570172 0 235800 0 1763769 0 845372 259481 249887 300785 269921 382038 0 0 180637 +(Gln->pyro-Glu)QYFTKPSIAK MGYG000000053_01407;MGYG000002867_01589;MGYG000003539_01166;MGYG000003467_00952;MGYG000000074_01517;MGYG000001415_00889;MGYG000004241_00281 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0828@1|root,COG0828@2|Bacteria,4NUPV@976|Bacteroidetes,2FUNX@200643|Bacteroidia,22VJS@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS21 family 1.0 rpsU 1.0 - 1.0 - 1.0 ko:K02970 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S21 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000053_01407 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02970:RP-S21, MRPS21, rpsU; small subunit ribosomal protein S21 1.0 none 1.0 0 0 0 0 0 0 0 0 538791 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 898402 0 0 0 0 0 0 556663 0 0 0 0 0 0 0 0 0 0 0 0 0 1396175 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYGHFYLVDTTAMDAAK MGYG000004185_01219;MGYG000002478_00808;MGYG000004797_04277 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,2FSBB@200643|Bacteroidia,22XXG@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004185_01219 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02864:RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 338663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 486714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYGVDTSDIVR MGYG000002517_00849;MGYG000000245_02379 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Kinase, PfkB family 1.0 - 1.0 - 1.0 2.7.1.45 1.0 ko:K00874 1.0 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 1.0 M00061,M00308,M00631 1.0 R01541 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00849 0.5 2-dehydro-3-deoxygluconokinase. KDG kinase. The enzyme shows no activity with 2-dehydro-3-deoxy-D-galactonate. cf. EC 2.7.1.178. 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D- gluconate + ADP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00874:kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] 1.0 none 1.0 162533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326435 0 0 0 0 150133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 823550 0 0 0 0 1054266 0 0 929312 0 0 0 0 0 0 0 0 380996 0 0 0 0 0 0 0 0 0 0 1062411 0 0 0 0 0 0 0 0 0 193786 0 0 0 0 0 0 0 220454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYIEKDAALER MGYG000002247_02283;MGYG000003307_01120;MGYG000002323_03113;MGYG000002476_03390;MGYG000002494_04638;MGYG000000262_01980;MGYG000002515_00455;MGYG000002506_02112;MGYG000000301_00104;MGYG000001315_03285;MGYG000000251_02717;MGYG000001338_00778;MGYG000000133_01006 domain d__Bacteria 1.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WH14@541000|Ruminococcaceae 0.3076923076923077 186801|Clostridia 0.6153846153846154 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 - 0.6153846153846154 - 1.0 ko:K03695,ko:K03696 0.6153846153846154 ko01100,ko04213,map01100,map04213 0.6153846153846154 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N,UVR 0.6153846153846154 - 1.0 - 1.0 - 1.0 GT4 1.0 MGYG000002247_02283 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways|Longevity regulating pathway - multiple species 0.6153846153846154 K03695:clpB; ATP-dependent Clp protease ATP-binding subunit ClpB|K03696:clpC; ATP-dependent Clp protease ATP-binding subunit ClpC 0.6153846153846154 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1336634 0 1372498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 979026 0 1424116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYIIDTIAQGGQK MGYG000002492_00882 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,3NHZR@46205|Pseudobutyrivibrio 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00882 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366117 0 0 0 0 568337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629730 0 0 0 0 0 0 0 0 0 978806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513039 0 0 0 0 0 0 0 0 0 537456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYIIGTAEKPR MGYG000004769_00454 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4H4PJ@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_00454 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 768460 813507 0 0 0 1194782 1131424 0 0 1141905 0 0 0 0 0 0 0 455473 0 413537 0 0 0 0 0 0 0 778037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYIQLASGISYK MGYG000000255_01360;MGYG000001338_01563 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2BJ52@1|root,32DE8@2|Bacteria,1UQYJ@1239|Firmicutes,258RQ@186801|Clostridia,3WMD6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Protein of unknown function (DUF2829) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF2829 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01360 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766991 0 0 0 0 0 0 +(Gln->pyro-Glu)QYLDHTVYVTYK MGYG000002478_03179 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG3489@1|root,COG3489@2|Bacteria,4NHKU@976|Bacteroidetes,2FTBK@200643|Bacteroidia,4AP8S@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Psort location CytoplasmicMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1771,Peptidase_M75 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_03179 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 991751 0 0 0 0 1099789 0 0 0 0 942321 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYLEETQSEVR MGYG000002469_00829;MGYG000001490_00724;MGYG000000756_01326;MGYG000003683_00731;MGYG000003452_01613;MGYG000001292_01866;MGYG000003120_01410;MGYG000002395_00735 family d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae 1.0 COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CZ6S@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Ribosomal protein S1 1.0 rpsA 1.0 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002469_00829 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYMEVMDQVR MGYG000003697_01173 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AWE5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01173 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534491 0 0 0 0 949026 0 0 0 0 504641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYPAEAEELFK MGYG000001345_00428;MGYG000000196_04414 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001345_00428 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYQNVEQDTKK MGYG000000243_00374;MGYG000004797_01916 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,2FMD0@200643|Bacteroidia,4AN66@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrB 1.0 - 1.0 1.6.5.8 1.0 ko:K00347 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQR2_RnfD_RnfE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00374 0.5 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 - 1.0 K00347:nqrB; Na+-transporting NADH:ubiquinone oxidoreductase subunit B [EC:7.2.1.1] 1.0 none 1.0 349067 418009 1074627 456018 688686 445098 0 0 0 0 0 0 1097378 0 0 862010 0 0 0 0 0 415973 0 458234 0 309906 0 0 0 0 600511 0 1119688 0 0 0 446134 960533 0 164577 128988 281023 284138 0 0 0 0 0 0 0 556264 0 0 536110 0 0 0 0 0 267069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587933 542324 996128 207199 526305 372229 0 0 0 0 0 0 0 455801 0 0 357246 0 0 0 0 0 861885 0 0 0 853652 0 0 0 0 280977 0 483760 0 0 0 1015691 0 872815 658445 613724 551435 356243 808893 0 0 0 0 0 0 1022087 0 0 0 0 0 0 0 0 776139 0 535547 0 703076 0 0 0 0 587217 0 383502 0 0 0 942960 788260 704535 845344 545246 0 238292 0 0 0 0 0 0 0 318548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468247 0 221609 0 0 0 0 925893 +(Gln->pyro-Glu)QYQPVN(Deamidated)GNIVFK MGYG000003681_03232;MGYG000001313_03346 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 2DKUK@1|root,30D8W@2|Bacteria,4NNND@976|Bacteroidetes,2G3DK@200643|Bacteroidia,4AQQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_03232 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 589138 0 0 285079 0 255067 0 0 187814 0 0 0 0 0 0 0 0 0 0 0 310117 0 0 0 0 0 0 0 0 0 0 0 0 722841 909401 1747892 0 0 1157995 543438 0 1572891 0 2266792 0 0 683200 0 0 0 0 0 0 3163107 0 0 0 961397 3000096 0 0 553777 0 693341 0 0 0 0 209568 0 0 971559 548233 1595948 0 0 0 912174 0 1138330 0 2095239 0 0 0 0 1963185 0 0 0 0 1794639 0 0 0 950100 1900866 0 0 1093836 0 786444 0 0 0 0 531542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 279128 0 0 0 0 327136 0 0 0 0 0 0 0 0 0 231802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYQPVNGN(Deamidated)IVFK MGYG000003681_03232;MGYG000001313_03346 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 2DKUK@1|root,30D8W@2|Bacteria,4NNND@976|Bacteroidetes,2G3DK@200643|Bacteroidia,4AQQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_03232 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 602604 0 0 0 0 423782 0 0 0 0 634618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431588 0 0 0 0 0 0 0 0 0 0 2509377 0 0 0 697982 0 715527 0 0 0 0 843379 0 0 0 0 0 0 0 0 0 946070 825731 0 0 0 0 738727 1169064 0 0 0 0 0 0 0 1633576 0 0 0 0 0 0 0 1363255 0 0 0 0 947583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702639 614392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYQPVNGNIVFK MGYG000003681_03232;MGYG000001313_03346 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 2DKUK@1|root,30D8W@2|Bacteria,4NNND@976|Bacteroidetes,2G3DK@200643|Bacteroidia,4AQQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_03232 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 405124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353040 0 0 358613 245228 634204 319546 0 889864 0 889286 0 0 1272662 0 1297437 470105 0 0 435124 2007346 403832 0 0 0 1555039 148155 0 418830 0 333387 0 567063 276482 0 602932 0 0 643698 0 0 974227 644639 507583 646714 0 649794 0 804769 0 0 922274 0 1575316 487510 0 0 615118 1193496 925021 0 0 0 1198324 702704 0 985577 0 410881 0 723704 634766 0 682588 0 0 0 0 0 0 267536 0 0 0 0 0 0 0 0 156286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295812 0 0 0 0 0 0 0 0 0 133800 0 0 0 329808 563127 385825 0 0 0 0 0 0 0 0 149081 0 0 0 0 262993 +(Gln->pyro-Glu)QYQVNSAMM(Oxidation)AQTGNPQVK MGYG000002494_02793 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline 1.0 argI 1.0 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.1.3.3,2.1.3.9 1.0 ko:K00611,ko:K09065 1.0 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 1.0 M00029,M00844,M00845 1.0 R01398,R07245 1.0 RC00096 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECS88_1305.ECS88_4841 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02793 1.0 ornithine carbamoyltransferase. | N-acetylornithine carbamoyltransferase. OTCase. | N-acetylornithine transcarbamylase. The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively. | Differs from EC 2.1.3.3.-!-This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic pathway of several eubacteria and has no catalytic activity with L-ornithine as substrate. carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate. | carbamoyl phosphate + N(2)-acetyl-L-ornithine = H(+) + N(2)-acetyl-L- citrulline + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00611:OTC, argF, argI; ornithine carbamoyltransferase [EC:2.1.3.3]|K09065:argF; N-acetylornithine carbamoyltransferase [EC:2.1.3.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYQVNSAMMAQTGNPQVK MGYG000002494_02793 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline 1.0 argI 1.0 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.1.3.3,2.1.3.9 1.0 ko:K00611,ko:K09065 1.0 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 1.0 M00029,M00844,M00845 1.0 R01398,R07245 1.0 RC00096 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECS88_1305.ECS88_4841 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02793 1.0 ornithine carbamoyltransferase. | N-acetylornithine carbamoyltransferase. OTCase. | N-acetylornithine transcarbamylase. The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively. | Differs from EC 2.1.3.3.-!-This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic pathway of several eubacteria and has no catalytic activity with L-ornithine as substrate. carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate. | carbamoyl phosphate + N(2)-acetyl-L-ornithine = H(+) + N(2)-acetyl-L- citrulline + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00611:OTC, argF, argI; ornithine carbamoyltransferase [EC:2.1.3.3]|K09065:argF; N-acetylornithine carbamoyltransferase [EC:2.1.3.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468964 0 0 0 951269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 947153 0 682585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYSDLSSPQKR MGYG000001300_00283;MGYG000003166_01347;MGYG000002641_00066 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3WIHG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit 1.0 rpsL 1.0 - 1.0 - 1.0 ko:K02950 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S12_S23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00283 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02950:RP-S12, MRPS12, rpsL; small subunit ribosomal protein S12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 909694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1021204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 540022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYSELEEEWKAEK MGYG000002515_00455;MGYG000002506_02112;MGYG000002494_04638 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,3XN3I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 1.0 - 1.0 ko:K03695 1.0 ko04213,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 MGYG000002515_00455 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - multiple species 1.0 K03695:clpB; ATP-dependent Clp protease ATP-binding subunit ClpB 1.0 none 1.0 0 0 0 0 0 465355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 539791 0 496408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1035351 0 575329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYSSQTAYDTDLK MGYG000000074_02389 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG0457@2|Bacteria,4PJ0T@976|Bacteroidetes,2G232@200643|Bacteroidia,22UIZ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_17,TPR_19,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02389 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYTGYKDMPR MGYG000000224_00462;MGYG000004748_03256;MGYG000001313_00060;MGYG000000105_02018;MGYG000002561_02189;MGYG000000236_01773;MGYG000002560_00250;MGYG000000243_01957;MGYG000001346_01505 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0096@1|root,COG0096@2|Bacteria,4NNFW@976|Bacteroidetes,2FRZ6@200643|Bacteroidia,22Y1I@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit 1.0 rpsH 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02994 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000224_00462 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02994:RP-S8, MRPS8, rpsH; small subunit ribosomal protein S8 1.0 none 1.0 0 0 1123513 0 0 0 0 910345 0 0 1155139 0 0 0 0 1114201 0 436967 0 0 841029 0 419655 0 0 0 0 0 1028959 0 0 0 1102595 1045296 0 0 0 994763 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327871 0 0 0 0 369931 0 0 1136773 0 0 0 0 0 0 711464 0 0 0 0 468984 0 0 0 0 905151 0 0 0 0 0 279031 0 0 0 0 0 0 0 0 0 0 0 750143 0 0 585946 0 0 0 0 424198 0 627598 0 0 802181 0 0 0 0 0 0 440335 685526 0 0 0 605986 622655 0 0 0 675480 0 0 0 0 0 0 0 0 0 0 1119623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYTHENAQASR MGYG000002171_02172;MGYG000000243_01313;MGYG000002478_03182;MGYG000001783_01513 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG3408@1|root,COG3408@2|Bacteria,4NF09@976|Bacteroidetes,2FMEX@200643|Bacteroidia,4ANWK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 glycogen debranching enzyme, archaeal type 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GDE_C,GDE_N 1.0 - 1.0 GH133 1.0 GH133 1.0 GH133 1.0 MGYG000002171_02172 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 442499 451018 952737 475231 0 646192 0 498984 0 0 389877 0 0 743464 0 1516083 810925 600682 0 0 0 693970 616024 736800 0 521814 0 495459 0 645299 820237 600345 854543 0 0 540729 562184 1028681 348978 228049 446342 366976 0 364844 0 449019 0 0 498871 0 0 417139 0 547462 410941 462871 0 0 0 140323 867938 150515 0 426289 0 316811 0 298705 360708 324039 334787 0 0 0 310834 301852 248060 0 301726 154721 0 0 0 0 0 0 308551 0 0 0 0 436559 0 264545 0 0 0 0 0 251688 0 0 0 0 0 0 212531 0 0 0 0 343065 175811 212731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305136 0 0 419784 0 347767 0 341405 0 0 361065 0 0 0 0 428601 150703 493740 0 0 0 0 526319 113755 0 418385 0 304470 0 293071 293158 363810 198174 0 0 0 420647 362718 +(Gln->pyro-Glu)QYVSNPEEYDFHK MGYG000000074_02412 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02412 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 591809 0 0 0 0 0 0 0 0 0 169538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 591766 0 0 800260 835224 629490 0 0 708118 0 0 0 771603 0 629592 542437 633950 0 1057379 1159995 537887 633150 0 467989 560462 849353 0 0 0 1002483 0 0 0 0 0 0 890372 0 +(Gln->pyro-Glu)QYYGETAEILK MGYG000002603_01229;MGYG000003697_00181;MGYG000002293_00655;MGYG000002080_00933 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0149@1|root,COG2259@1|root,COG0149@2|Bacteria,COG2259@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 DoxX,MauE,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002603_01229 0.25 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 343739 1629667 0 438967 0 0 0 0 0 0 0 0 0 582557 0 0 0 0 0 282036 0 1227532 0 0 0 0 0 0 0 0 1146412 0 0 0 0 838905 0 796474 723151 600088 0 1065003 0 0 0 0 0 0 783197 0 0 600681 0 0 0 0 0 235629 0 475901 0 0 0 0 0 0 0 0 288169 0 0 0 0 223949 0 0 722271 1110775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 818423 0 1131676 0 0 0 0 0 0 0 0 421193 0 0 0 0 1224384 0 1078811 1447553 1138923 0 1276292 0 0 0 0 0 0 1168242 0 0 1342459 0 0 0 0 0 1285616 0 1236200 0 0 0 0 0 0 0 0 1179739 0 0 0 0 1190991 0 256292 273609 377272 0 371789 0 0 0 0 0 0 395647 0 0 325755 0 0 0 0 0 220119 0 488036 0 0 0 0 0 0 0 0 485372 0 0 0 0 511455 +(Gln->pyro-Glu)QYYGETAEILKEK MGYG000002603_01229;MGYG000003697_00181 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0149@1|root,COG2259@1|root,COG0149@2|Bacteria,COG2259@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 DoxX,MauE,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002603_01229 0.5 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850519 0 0 0 0 727091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Gln->pyro-Glu)QYYGETSATLNKK MGYG000000074_01931;MGYG000000003_00056;MGYG000000437_01534 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia,22UAZ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01931 0.3333333333333333 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 577692 0 0 0 628633 0 0 485693 0 0 0 815947 0 0 643599 1019599 0 436811 0 0 406894 0 0 0 436848 640856 0 0 976014 0 601400 0 0 0 0 0 0 529060 189128 848635 549769 525706 481273 0 0 851130 0 0 0 279648 0 0 574463 396184 0 555666 594194 0 437134 0 284910 320868 498752 551392 0 617304 854738 0 654285 574242 0 559262 0 806334 484083 454268 338558 679415 0 379453 452283 0 0 601699 0 0 0 0 0 0 0 518359 0 497563 505993 0 345743 0 377348 285212 561301 0 0 0 653618 0 0 384960 0 536865 0 0 474565 0 0 0 0 0 0 0 0 0 0 0 0 217580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1130870 1283515 1348605 2023564 1867547 1933563 0 0 1418533 0 0 0 1803891 0 0 1499875 1405116 0 2787889 2082504 0 1150608 0 1038123 951165 1413087 941698 0 1556281 2151548 0 1683114 1187537 0 1441104 0 1490787 1474516 +(Glu->pyro-Glu)EFAENEVKPLAQEVDETEEFPVENVKK MGYG000002517_00542 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00542 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2845898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu)EGGHTVGSGVVSK MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027;MGYG000003504_00096 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.8333333333333334 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002059_00460 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu)EGMGAFLEKR MGYG000002492_00917;MGYG000002670_01219;MGYG000002953_01330;MGYG000002143_01789;MGYG000003185_01503;MGYG000000099_01614;MGYG000001502_02387;MGYG000002926_00641;MGYG000001564_00906;MGYG000003869_00107;MGYG000004271_02656;MGYG000002673_01999;MGYG000002156_02025;MGYG000000271_02750;MGYG000002517_02338;MGYG000000164_00684;MGYG000003694_02682;MGYG000000489_01666;MGYG000003589_00701;MGYG000000356_02284;MGYG000004276_00459;MGYG000004489_00132 domain d__Bacteria 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.3181818181818182 186801|Clostridia 0.9545454545454546 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5454545454545454 crt 0.9545454545454546 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.045454545454545456 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 696715 0 0 0 0 718050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453275 0 0 0 0 412306 0 0 690606 0 0 0 0 0 0 0 0 453549 0 0 0 0 537901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 574356 0 0 0 0 456832 +(Glu->pyro-Glu)EHILLAR MGYG000000042_01421;MGYG000004464_00178;MGYG000001673_01975;MGYG000004704_00398;MGYG000000089_01901;MGYG000004288_00862;MGYG000002619_00483;MGYG000000412_01546;MGYG000002259_00929;MGYG000002926_00232;MGYG000000099_01234;MGYG000004763_01689;MGYG000003681_02037;MGYG000001384_04567;MGYG000003937_01027;MGYG000002707_01740;MGYG000002994_01317;MGYG000001313_00097;MGYG000003266_00392;MGYG000002455_03884;MGYG000000348_00283;MGYG000001776_00769;MGYG000000044_01721;MGYG000001672_00396;MGYG000002059_00460;MGYG000002685_01157;MGYG000002557_00102;MGYG000000196_03974;MGYG000001008_02651;MGYG000001661_02666;MGYG000001300_00280;MGYG000004769_00437;MGYG000002084_01252;MGYG000000433_00368;MGYG000003022_00748;MGYG000002040_01212;MGYG000002098_01616;MGYG000003266_00955;MGYG000000098_02017;MGYG000001757_01274;MGYG000001299_01777;MGYG000002224_01123;MGYG000002438_02321;MGYG000000163_00957;MGYG000004285_00597;MGYG000001346_01533;MGYG000003073_01160;MGYG000001616_00520;MGYG000003921_01124;MGYG000001238_02207;MGYG000002996_00986;MGYG000002052_00232;MGYG000002418_00753;MGYG000002448_02351;MGYG000000223_03134;MGYG000003352_00730;MGYG000001319_01764;MGYG000004757_00594;MGYG000001365_00649;MGYG000002695_01057;MGYG000000138_00665;MGYG000004769_00412;MGYG000001630_01142;MGYG000002673_02521;MGYG000003022_00735;MGYG000004717_00227;MGYG000000365_00508;MGYG000004276_00122;MGYG000001925_01419;MGYG000000273_00431;MGYG000000867_00556;MGYG000004788_02115;MGYG000000291_00377;MGYG000003202_00129;MGYG000002993_01302;MGYG000000357_02040;MGYG000002953_03321;MGYG000003546_00955;MGYG000000375_01434;MGYG000000022_02283;MGYG000002901_00528;MGYG000003446_00658;MGYG000003899_01642;MGYG000003891_00382;MGYG000002925_00238;MGYG000003428_00555;MGYG000000490_01981;MGYG000003686_02367;MGYG000001356_01661;MGYG000001655_02933;MGYG000003977_00001;MGYG000003166_01350;MGYG000003170_00035;MGYG000002905_00001;MGYG000002972_00178;MGYG000002098_00731;MGYG000002702_01978;MGYG000002912_01340;MGYG000003424_00456;MGYG000001789_00154;MGYG000001567_01738;MGYG000000182_00585;MGYG000003441_00074;MGYG000000236_01807;MGYG000003701_03123;MGYG000000084_02000;MGYG000002291_02272;MGYG000004642_00846;MGYG000000187_02029;MGYG000002641_00069;MGYG000001500_01929;MGYG000003170_00048;MGYG000000445_01370;MGYG000002272_01482;MGYG000004221_01651;MGYG000000243_01988;MGYG000001780_03476;MGYG000001665_01696;MGYG000003504_00096;MGYG000001421_00009;MGYG000001646_01118;MGYG000004047_00605 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.1721311475409836 186801|Clostridia 0.45081967213114754 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9590163934426229 - 1.0 ko:K02358 0.9836065573770492 - 0.9836065573770492 - 0.9836065573770492 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9836065573770492 - 0.9836065573770492 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.00819672131147541 - - - - 1.0 1.0 1.0 1.0 - 0.9836065573770492 K02358:tuf, TUFM; elongation factor Tu 0.9836065573770492 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1112560 0 0 0 0 0 0 0 0 1108220 0 1207621 0 0 0 0 0 918570 0 0 0 0 1195263 0 0 0 0 1405735 0 0 407963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032510 0 0 0 +(Glu->pyro-Glu)EHILLSR MGYG000000080_02058;MGYG000000245_03248;MGYG000001688_04229;MGYG000001654_02237;MGYG000004718_00646;MGYG000004735_00884;MGYG000000280_01200;MGYG000004565_01266;MGYG000001714_01291;MGYG000001760_00949;MGYG000000198_01165;MGYG000004893_00932;MGYG000000392_00966;MGYG000003324_00542;MGYG000002563_00522;MGYG000001507_06245;MGYG000000133_02991;MGYG000000919_01815;MGYG000004879_01608;MGYG000001234_01151;MGYG000001623_00993;MGYG000000466_00679;MGYG000000446_00437;MGYG000002202_00030;MGYG000003208_02857;MGYG000002563_00509;MGYG000003895_00135;MGYG000001619_01314;MGYG000000216_02406;MGYG000002517_00205;MGYG000000034_01346;MGYG000000123_01153;MGYG000004296_01668;MGYG000000277_00173;MGYG000004508_00787;MGYG000001469_02077;MGYG000001431_01181;MGYG000001809_00576;MGYG000001652_01300;MGYG000000127_03982;MGYG000000258_00266;MGYG000002670_00364;MGYG000004502_00031;MGYG000004600_00789;MGYG000001635_01137;MGYG000000139_00697;MGYG000001611_00087;MGYG000000255_02009;MGYG000000404_00531;MGYG000000164_01096;MGYG000000018_00453;MGYG000002234_01026;MGYG000000032_01232;MGYG000001777_01732;MGYG000002105_00002;MGYG000000347_00343;MGYG000000532_02409;MGYG000002136_02858;MGYG000003146_01522;MGYG000002286_02469;MGYG000000262_00030;MGYG000001412_04734;MGYG000002772_01895;MGYG000002492_00344;MGYG000003753_00317;MGYG000001615_01716;MGYG000002854_00111;MGYG000001487_02232;MGYG000000143_00646;MGYG000000016_02519;MGYG000002279_01932;MGYG000000201_03875;MGYG000002485_02622;MGYG000004547_01366;MGYG000003063_00662;MGYG000004893_01944;MGYG000000271_03365;MGYG000000185_02848;MGYG000000230_00429;MGYG000001315_01207;MGYG000001602_02247;MGYG000001508_00032;MGYG000001464_00103;MGYG000001558_01002;MGYG000001400_03001;MGYG000001405_04470;MGYG000001310_01963;MGYG000003273_00234;MGYG000000140_01590;MGYG000001404_04883;MGYG000000323_00619;MGYG000001065_02730;MGYG000002528_01098;MGYG000004302_00459;MGYG000004680_02443;MGYG000002609_01147;MGYG000001436_02249;MGYG000000263_00836;MGYG000000157_01091;MGYG000004789_00520;MGYG000000179_00920;MGYG000000134_02651;MGYG000002839_00878;MGYG000000217_01428;MGYG000000173_00405;MGYG000000177_01044;MGYG000001485_02164;MGYG000002290_01325;MGYG000001531_00906;MGYG000002220_00457;MGYG000002195_01684;MGYG000001607_01045;MGYG000000226_00644;MGYG000001141_02439;MGYG000000024_03409;MGYG000003425_03741;MGYG000000251_00064;MGYG000002444_02629;MGYG000000233_00807;MGYG000000142_00171;MGYG000000121_02189;MGYG000001528_00736;MGYG000004087_00551;MGYG000001439_02427;MGYG000000242_00282;MGYG000004216_00603;MGYG000002417_01244;MGYG000002126_00299;MGYG000000335_01138;MGYG000002854_00124;MGYG000001698_04050;MGYG000004558_00415;MGYG000003074_01359;MGYG000000037_01050;MGYG000002837_02416;MGYG000002997_01472;MGYG000000193_02083;MGYG000002212_00196;MGYG000000249_00026;MGYG000003236_02455;MGYG000000121_03149;MGYG000004799_01385;MGYG000000501_01307;MGYG000004630_01824;MGYG000000045_02616;MGYG000001814_01592;MGYG000003656_01823;MGYG000001432_01745;MGYG000003486_01055;MGYG000001617_01406;MGYG000002596_02296;MGYG000001712_00119;MGYG000003620_01283;MGYG000001007_01315;MGYG000003486_01459;MGYG000001732_00030;MGYG000000206_00901;MGYG000004733_01211 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.13924050632911392 186801|Clostridia 0.740506329113924 J 0.9873417721518988 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9810126582278481 tuf 0.9873417721518988 - 0.8164556962025317 - 0.9936708860759493 ko:K02358 0.930379746835443 - 0.9367088607594937 - 0.9430379746835443 - 0.9936708860759493 - 0.9936708860759493 ko00000,ko03012,ko03029,ko04147 0.930379746835443 - 0.9430379746835443 - 0.9936708860759493 - 0.930379746835443 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 0.9873417721518988 - 0.9936708860759493 - 0.9936708860759493 - 0.9936708860759493 - 0.9936708860759493 MGYG000000080_02058 0.006329113924050633 - - - - 0.9936708860759493 0.9936708860759493 0.9936708860759493 0.9936708860759493 - 0.9367088607594937 K02358:tuf, TUFM; elongation factor Tu 0.930379746835443 none 1.0 511134 0 237422 244930 876653 0 0 0 0 818192 0 620917 0 0 909461 0 524579 720929 0 0 0 0 128074 0 0 288067 252407 387637 220476 0 0 550359 0 575141 325995 0 214993 575007 331697 0 274525 516586 450839 0 0 0 0 218212 0 340879 0 0 270730 0 165876 720889 0 0 0 0 495383 0 0 201435 394738 764906 370845 0 0 377758 0 549022 452082 0 343925 456359 1114254 0 973728 992215 220250 0 0 0 0 1069351 0 477635 0 0 1097886 0 849945 0 0 0 0 0 695582 0 0 842335 1162213 1158843 984717 0 0 1309867 1011204 1294390 1121310 0 823647 793938 519724 0 433478 835790 527388 0 0 0 0 545656 0 414895 0 0 627604 0 595790 247198 0 0 0 0 0 0 0 717548 836405 210443 650149 0 0 756970 589341 526907 745637 0 732970 508831 1009305 0 1605992 1358655 418807 0 0 0 0 1483800 0 1388992 0 0 1413985 0 1255282 275154 0 0 0 0 529918 0 0 966106 1173193 438157 1924351 0 0 1076145 1957743 1371534 1291494 0 1297436 1149790 +(Glu->pyro-Glu)EHLLLAR MGYG000000408_01653;MGYG000004732_02398;MGYG000000089_01901;MGYG000000362_00956;MGYG000003547_00975;MGYG000002259_00929;MGYG000001754_00089;MGYG000004694_00667;MGYG000003155_00314;MGYG000004763_01689;MGYG000004685_00908;MGYG000001384_04567;MGYG000003937_01027;MGYG000003992_01709;MGYG000002455_03884;MGYG000000348_00283;MGYG000001672_00396;MGYG000002059_00460;MGYG000001008_02651;MGYG000000196_03974;MGYG000004573_00004;MGYG000001434_01407;MGYG000001661_02666;MGYG000001541_00185;MGYG000001300_00280;MGYG000003851_00676;MGYG000004769_00437;MGYG000002084_01252;MGYG000003869_01538;MGYG000002578_00911;MGYG000000433_00368;MGYG000000349_00457;MGYG000002040_01212;MGYG000000054_03933;MGYG000004528_00894;MGYG000002794_01318;MGYG000001606_01669;MGYG000000202_03457;MGYG000003442_01057;MGYG000004474_01617;MGYG000003868_01133;MGYG000001359_01254;MGYG000002224_01123;MGYG000004201_01254;MGYG000000036_01380;MGYG000003410_00864;MGYG000003073_01160;MGYG000001616_00520;MGYG000002052_00232;MGYG000002418_00753;MGYG000000369_00927;MGYG000000223_03134;MGYG000003352_00730;MGYG000001334_00218;MGYG000002447_00587;MGYG000004757_00594;MGYG000001365_00649;MGYG000002116_00788;MGYG000002695_01057;MGYG000001756_00183;MGYG000003819_01356;MGYG000004769_00412;MGYG000000395_01440;MGYG000001524_01606;MGYG000001193_00787;MGYG000004724_00878;MGYG000000802_00776;MGYG000000372_00001;MGYG000000273_00431;MGYG000000291_00377;MGYG000003202_00129;MGYG000002944_02285;MGYG000002281_02290;MGYG000002447_00574;MGYG000002993_01302;MGYG000002953_03321;MGYG000003546_00955;MGYG000000022_02283;MGYG000002470_01245;MGYG000000375_01434;MGYG000002901_00528;MGYG000000090_01714;MGYG000001737_01514;MGYG000003891_00382;MGYG000003428_00555;MGYG000000490_01981;MGYG000003686_02367;MGYG000001784_02227;MGYG000001749_02490;MGYG000002980_01277;MGYG000001779_00600;MGYG000001356_01661;MGYG000000488_00776;MGYG000000479_00469;MGYG000002930_00867;MGYG000004526_00639;MGYG000003166_01350;MGYG000003868_01166;MGYG000001677_00114;MGYG000003170_00035;MGYG000002905_00001;MGYG000001590_00854;MGYG000002098_00731;MGYG000002912_01340;MGYG000002702_01978;MGYG000003424_00456;MGYG000000182_00585;MGYG000003441_00074;MGYG000002143_01659;MGYG000000084_02000;MGYG000002291_02272;MGYG000004642_00846;MGYG000004300_00119;MGYG000001559_00042;MGYG000000945_00137;MGYG000000187_02029;MGYG000003185_01053;MGYG000000420_01950;MGYG000003170_00048;MGYG000000445_01370;MGYG000002272_01482;MGYG000004221_01651;MGYG000001444_01618;MGYG000003516_01606;MGYG000000243_01988;MGYG000001780_03476;MGYG000004657_01190;MGYG000002540_03367;MGYG000000254_02569;MGYG000001646_01118;MGYG000003660_00194;MGYG000002042_00774;MGYG000002970_01555;MGYG000003013_00349;MGYG000003484_00308;MGYG000000117_01463;MGYG000002659_00459;MGYG000000042_01421;MGYG000003096_01037;MGYG000002106_00224;MGYG000004464_00178;MGYG000004704_00398;MGYG000001673_01975;MGYG000000385_01364;MGYG000004288_00862;MGYG000002619_00483;MGYG000000412_01546;MGYG000000930_01271;MGYG000002926_00232;MGYG000002578_00898;MGYG000000099_01234;MGYG000003460_01161;MGYG000003681_02037;MGYG000001739_00819;MGYG000002707_01740;MGYG000003185_01074;MGYG000001444_01634;MGYG000002994_01317;MGYG000002165_00803;MGYG000001313_00097;MGYG000002654_00465;MGYG000003266_00392;MGYG000004119_01204;MGYG000004482_01535;MGYG000001576_02230;MGYG000001824_01594;MGYG000003628_01000;MGYG000001563_01273;MGYG000001776_00769;MGYG000000044_01721;MGYG000003549_00407;MGYG000002685_01157;MGYG000004800_00190;MGYG000002762_01733;MGYG000003022_00748;MGYG000001502_01278;MGYG000002098_01616;MGYG000003266_00955;MGYG000004826_01022;MGYG000000098_02017;MGYG000003274_01474;MGYG000001757_01274;MGYG000001299_01777;MGYG000002950.1_00050;MGYG000002438_02321;MGYG000002556_01332;MGYG000000163_00957;MGYG000000267_01379;MGYG000001346_01533;MGYG000004285_00597;MGYG000000333_00136;MGYG000004196_01067;MGYG000003497_00215;MGYG000002768_00022;MGYG000002057_01066;MGYG000003921_01124;MGYG000001238_02207;MGYG000002996_00986;MGYG000002448_02351;MGYG000004475_00887;MGYG000000168_03211;MGYG000001319_01764;MGYG000001881_00748;MGYG000004847_01222;MGYG000000138_00665;MGYG000001630_01142;MGYG000002673_02521;MGYG000003022_00735;MGYG000003528_02124;MGYG000001516_01186;MGYG000004717_00227;MGYG000004726_01622;MGYG000004276_00122;MGYG000000365_00508;MGYG000001925_01419;MGYG000004788_02115;MGYG000000266_00259;MGYG000001503_00139;MGYG000000449_00614;MGYG000000120_01190;MGYG000003446_00658;MGYG000001552_00984;MGYG000003899_01642;MGYG000000013_02251;MGYG000003583_01411;MGYG000002925_00238;MGYG000001655_02933;MGYG000001991_00383;MGYG000003977_00001;MGYG000003872_01017;MGYG000002972_00178;MGYG000001567_01738;MGYG000001789_00154;MGYG000000236_01807;MGYG000003701_03123;MGYG000003389_01825;MGYG000004694_00680;MGYG000001559_01093;MGYG000002641_00069;MGYG000000733_01034;MGYG000002114_00077;MGYG000001500_01929;MGYG000000370_00784;MGYG000002006_00835;MGYG000000622_01283;MGYG000002720_00092;MGYG000004746_00230;MGYG000001665_01696;MGYG000003504_00096;MGYG000001421_00009;MGYG000002848_00884;MGYG000003001_00359;MGYG000004047_00605;MGYG000000673_00997 life d__Bacteria 0.9961 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.16141732283464566 186801|Clostridia 0.484251968503937 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.952755905511811 - 1.0 ko:K02358 0.984251968503937 - 0.984251968503937 - 0.984251968503937 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.984251968503937 - 0.984251968503937 - 1.0 - 0.9881889763779528 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000408_01653 0.003937007874015748 - - - - 1.0 1.0 1.0 1.0 - 0.984251968503937 K02358:tuf, TUFM; elongation factor Tu 0.984251968503937 none 1.0 982443 0 1123225 0 0 1096118 0 0 763854 0 0 220569 1847175 0 928460 1637824 0 1527825 0 0 0 1050793 1102718 1038990 0 1025156 1011133 1159515 0 0 0 0 1396539 0 0 0 996447 1064930 967219 0 0 0 0 991837 0 0 1301465 0 0 0 1343930 0 1073465 1167351 0 1062085 0 0 0 744806 1377658 883909 0 1227051 1013610 1189745 0 0 0 0 950645 0 0 0 1084015 1223856 876721 0 935552 0 0 906279 0 0 910020 0 0 497373 1044088 0 692984 836317 0 1270124 0 0 0 697565 1362012 952931 0 802240 832730 1468822 0 0 0 0 860189 0 0 0 886354 782330 451632 0 288699 0 0 435629 0 0 420835 0 0 646882 877832 0 401344 650909 0 414734 0 0 0 446348 450604 379379 0 478276 394246 179433 0 0 0 0 489596 0 0 0 495553 445128 677093 0 602321 0 0 1040811 0 0 895089 0 0 1216063 1269887 0 729062 1122729 0 1806153 0 0 0 566274 1794548 1365404 0 817463 624701 1570308 0 0 0 0 442280 0 0 0 702505 995462 +(Glu->pyro-Glu)ELNLDAIHDTVHEMAKDEAR MGYG000000278_01143;MGYG000004866_00011;MGYG000000084_01252;MGYG000001157_01204;MGYG000001627_00301;MGYG000003921_01704 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3WGYN@541000|Ruminococcaceae 0.8333333333333334 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.8333333333333334 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000278_01143 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 847048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl)EAGLYKNER MGYG000000243_01844 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FN0E@200643|Bacteroidia,22WXW@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA 1.0 kbl 1.0 - 1.0 2.3.1.29 1.0 ko:K00639 1.0 ko00260,map00260 1.0 - 1.0 R00371 1.0 RC00004,RC00394 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01844 1.0 glycine C-acetyltransferase. 2-amino-3-ketobutyrate coenzyme A ligase. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism 1.0 K00639:kbl, GCAT; glycine C-acetyltransferase [EC:2.3.1.29] 1.0 none 1.0 0 0 0 0 0 461488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459267 0 421665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 266678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 130026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl)EGEELAALNPHIVVK MGYG000002549_02719;MGYG000001378_02110;MGYG000000013_01251;MGYG000002470_00140;MGYG000003351_02105;MGYG000000243_01624;MGYG000001661_03030;MGYG000000105_01128;MGYG000001346_02599;MGYG000004899_00244;MGYG000002478_03826;MGYG000004823_01716;MGYG000003681_01529;MGYG000000224_01690;MGYG000004876_00604;MGYG000000174_01155;MGYG000004763_01631 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,2FNM3@200643|Bacteroidia,4AM98@815|Bacteroidaceae 0.9411764705882353 976|Bacteroidetes 1.0 F 1.0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616,ko:K08314 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CBS,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_02719 0.058823529411764705 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00616:TALDO1, talB, talA; transaldolase [EC:2.2.1.2]|K08314:fsaB, talC; fructose-6-phosphate aldolase 2 [EC:4.1.2.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl)EGGLVTAGNASGINDGAAAIVVMSEEK MGYG000000997_00552;MGYG000004271_00231;MGYG000002278_01891;MGYG000000245_02019;MGYG000000280_01473;MGYG000000271_02104;MGYG000001637_02269;MGYG000002517_00540;MGYG000003694_00877;MGYG000000153_01463;MGYG000000389_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.9090909090909091 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_00552 0.09090909090909091 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl)ENGIIHGTASLFR MGYG000002478_01935 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01935 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 83774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416230 0 0 0 0 555655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 373134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))EAFPGDVFYLHSR MGYG000002323_04217;MGYG000001785_00791;MGYG000002532_03724;MGYG000000093_05346;MGYG000002366_00008;MGYG000002515_03905;MGYG000002421_01630;MGYG000002385_03599;MGYG000002494_02406;MGYG000002506_03404 domain d__Bacteria 1.0 COG0056@1|root,COG0056@2|Bacteria,1MUG7@1224|Proteobacteria,1RP4V@1236|Gammaproteobacteria,3XP3D@561|Escherichia 0.7 1236|Gammaproteobacteria 0.7 F 0.7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 0.8 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 iSbBS512_1146.SbBS512_E4187 0.7 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 0.8 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000002323_04217 0.1 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1072617 1162989 0 696910 0 0 0 0 0 0 381495 0 0 0 0 0 0 848025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1027280 0 115924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 52576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))EAGMNDVVLVGGR MGYG000002492_01331;MGYG000000280_02128;MGYG000000356_00314 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 0.3333333333333333 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002492_01331 0.3333333333333333 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))EGASKAEAEDIKAK MGYG000002528_01112;MGYG000000028_00269 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,36IQP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01112 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))EGLDVLEYFISAHGAR MGYG000002528_01102;MGYG000000198_01126;MGYG000000179_00949;MGYG000001714_01233;MGYG000002445_01330;MGYG000001683_01329;MGYG000000262_00026 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,21Y1Y@1506553|Lachnoclostridium 0.42857142857142855 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000002528_01102 0.14285714285714285 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))EGLNPIKEEMAK MGYG000000184_01931;MGYG000000213_04019;MGYG000001338_00282 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3XYME@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 1.1.1.38 1.0 ko:K00027 1.0 ko00620,ko01200,ko02020,map00620,map01200,map02020 1.0 - 1.0 R00214 1.0 RC00105 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_01931 0.3333333333333333 malate dehydrogenase (oxaloacetate-decarboxylating). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon metabolism|Two-component system 1.0 K00027:ME2, sfcA, maeA; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392638 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 536690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238794 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))EIAEATDFVDGR MGYG000001292_01122;MGYG000003683_00464;MGYG000000756_00775;MGYG000001490_00981;MGYG000002469_01093;MGYG000002396_01111 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001292_01122 0.16666666666666666 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00616:TALDO1, talB, talA; transaldolase [EC:2.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))EITAEDTADMLK MGYG000002494_01063 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1282@1|root,2QQ0A@2759|Eukaryota,38CB0@33154|Opisthokonta,3BDQK@33208|Metazoa,3CWZ6@33213|Bilateria,41XXS@6656|Arthropoda,3SFQ1@50557|Insecta,450JW@7147|Diptera 1.0 33208|Metazoa 1.0 C 1.0 NAD(P) transhydrogenase beta subunit 1.0 - 1.0 - 1.0 1.6.1.2 1.0 ko:K00323 1.0 ko00760,ko01100,map00760,map01100 1.0 - 1.0 R00112 1.0 RC00001 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 AlaDh_PNT_C,AlaDh_PNT_N,PNTB,PNTB_4TM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01063 1.0 proton-translocating NAD(P)(+) transhydrogenase. - The enzyme is a membrane bound proton-translocating pyridine nucleotide transhydrogenase that couples the reversible reduction of NADP by NADH to an inward proton translocation across the membrane.-!-In the bacterium Escherichia coli the enzyme provides a major source of cytosolic NADPH.-!-Detoxification of reactive oxygen species in mitochondria by glutathione peroxidases depends on NADPH produced by this enzyme.-!-Formerly EC 1.6.1.2 and EC 1.6.1.5. H(+)(in) + NAD(+) + NADPH = H(+)(out) + NADH + NADP(+). 1.0 1.0 1.0 1.0 Nicotinate and nicotinamide metabolism|Metabolic pathways 1.0 K00323:NNT; proton-translocating NAD(P)+ transhydrogenase [EC:7.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1474830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1717325 0 0 3105056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3186122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429611 0 0 0 0 319454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1877928 0 0 0 0 2856959 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))EMFIANTTGTSSTDRIEGMIK MGYG000001315_00856 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0416@1|root,COG0416@2|Bacteria,1TPY8@1239|Firmicutes,248BX@186801|Clostridia,27K0U@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Fatty acid synthesis protein 1.0 grdD 1.0 - 1.0 1.21.4.2,1.21.4.3,1.21.4.4 1.0 ko:K21576 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 FA_synthesis 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_00856 1.0 glycine reductase. | sarcosine reductase. | betaine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. | The reaction is observed only in the direction of sarcosine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.4. | The reaction is observed only in the direction of betaine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.3. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. | [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine. | [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate. 1.0 1.0 1.0 1.0 - 1.0 K21576:grdD; glycine/sarcosine/betaine reductase complex component C subunit alpha [EC:1.21.4.2 1.21.4.3 1.21.4.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125351 0 0 0 0 0 0 0 0 0 0 0 0 370785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603442 0 0 0 0 0 0 0 0 0 0 483139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))EQVEMIEER MGYG000002506_02717 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3XNX9@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 K 1.0 transcriptional regulator 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02717 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 2157545 0 0 0 0 0 0 1667379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3124225 0 0 0 0 0 0 898334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2174949 0 0 0 0 0 0 395563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 615237 0 0 0 0 0 0 2907047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))ERPIDENLGSYEDVDEAVK MGYG000001338_02427;MGYG000000184_00682;MGYG000000200_00069 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02427 0.3333333333333333 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1296747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))ETANMISFMADVIGIR MGYG000000262_01807;MGYG000001531_01879;MGYG000004799_00956;MGYG000000249_00985;MGYG000000268_02435;MGYG000000179_04170;MGYG000001714_00587;MGYG000001065_01053;MGYG000001619_01751;MGYG000000198_04461;MGYG000001496_02433 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0078@1|root,COG0078@2|Bacteria,1TNY4@1239|Firmicutes,249P4@186801|Clostridia,26870@186813|unclassified Clostridiales 0.36363636363636365 186801|Clostridia 1.0 E 1.0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 0.7272727272727273 ygeW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_01807 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))ETVPVFHVGDTVK MGYG000000179_01851 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,2206I@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 - 1.0 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_01851 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02884:RP-L19, MRPL19, rplS; large subunit ribosomal protein L19 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glu->pyro-Glu+Methyl_2H(2)13C(1))EVNELATILKEEYGIEPAAAAVAVAAGPAAGAAAAEEK MGYG000004797_04276;MGYG000002478_00807 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_04276 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5716024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glucuronyl)VVQHNITAMNANR MGYG000000562_01318;MGYG000004271_01770;MGYG000000271_01499;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.75 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000562_01318 0.25 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 3273205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Glucuronyl)VVQHNLTAMNANR MGYG000004271_01770;MGYG000000153_01160;MGYG000000271_01499;MGYG000000404_00502;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.6 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01770 0.2 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 1519017 0 0 0 0 0 0 0 0 3089803 0 0 0 0 0 2656109 1088197 0 950298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368941 0 0 0 0 0 316225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1484673 0 0 0 0 0 2751080 1475311 0 718686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352680 0 0 0 0 0 765527 0 0 397445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Guanidinyl)AAFEEAEHAAK MGYG000003509_00509;MGYG000000177_00118;MGYG000002026_00456;MGYG000003891_00390;MGYG000004769_01404;MGYG000000198_03730;MGYG000000172_04155;MGYG000004087_01663;MGYG000001434_00926;MGYG000000198_03710;MGYG000004087_01662;MGYG000001564_01103;MGYG000001311_01511;MGYG000001493_02801;MGYG000001493_02800;MGYG000003422_00075;MGYG000004713_00792 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,21YU6@1506553|Lachnoclostridium 0.5294117647058824 186801|Clostridia 0.8823529411764706 C 1.0 Rubrerythrin 0.6470588235294118 rbr3A 0.9411764705882353 - 0.9411764705882353 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.8823529411764706 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003509_00509 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Guanidinyl)AINSGVTDKYK MGYG000003266_00038 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900762015|m__MGYG000003266 1.0 COG3444@1|root,COG3444@2|Bacteria,2GR9K@201174|Actinobacteria,4CVTK@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 PTS system sorbose subfamily IIB component 1.0 - 1.0 - 1.0 - 1.0 ko:K19507 1.0 ko02060,map02060 1.0 M00764 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.6.1.19 1.0 - 1.0 - 1.0 PTSIIB_sorb 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003266_00038 1.0 - - - - 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 K19507:gfrB; fructoselysine/glucoselysine PTS system EIIB component [EC:2.7.1.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Guanidinyl)EGLATGLGDEGGFAPK MGYG000003683_00763;MGYG000003452_01522 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CYT3@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000003683_00763 0.5 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1921627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Guanidinyl)EGVANKDKPLVWFNR MGYG000004735_00164 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00164 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 879063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1555970 0 0 0 0 0 0 0 0 0 +(Guanidinyl)IPEPEHENDKPFLMPVEDVFTITGR MGYG000002052_00232 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum|s__|m__MGYG000002052 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002052_00232 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 474651048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Guanidinyl)NISIAEKGHEER MGYG000002455_00941;MGYG000002470_04315;MGYG000002549_03230;MGYG000001378_00441;MGYG000000054_04429;MGYG000000029_03153;MGYG000000098_02688;MGYG000001337_00622;MGYG000000236_03467;MGYG000004464_01206;MGYG000000196_03295 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1592@1|root,COG1592@2|Bacteria,4NH0J@976|Bacteroidetes,2FNC9@200643|Bacteroidia,4AKRD@815|Bacteroidaceae 0.9090909090909091 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 0.9090909090909091 rbr 1.0 GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_00941 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331405 0 0 0 0 0 0 0 353989 0 275891 0 0 0 0 271090 0 0 0 0 349642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Guanidinyl)SAAELNEELVAAKK MGYG000000038_01584;MGYG000000213_00206;MGYG000000184_01180;MGYG000002945_02576;MGYG000002845_00986;MGYG000001607_01093;MGYG000004733_00976;MGYG000000206_01042;MGYG000001496_03128;MGYG000001748_00602;MGYG000001710_03003;MGYG000001338_02799;MGYG000000200_01105;MGYG000002966_02567;MGYG000000002_00874;MGYG000001698_02694;MGYG000000118_00226;MGYG000000133_00053;MGYG000000301_00168;MGYG000002279_01064 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3Y0MW@572511|Blautia 0.45 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uL29 family 1.0 rpmC 1.0 - 1.0 - 1.0 ko:K02904 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L29 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_01584 0.05 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02904:RP-L29, rpmC; large subunit ribosomal protein L29 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1259727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Guanidinyl)SNVIVKDNESLDSALRR MGYG000001065_00121;MGYG000001954_00183;MGYG000001531_02509;MGYG000000087_00069;MGYG000000278_03375;MGYG000001606_01557;MGYG000000255_00059;MGYG000002417_00179;MGYG000002445_00245 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 0.7777777777777778 203691|Spirochaetes 0.7777777777777778 L 0.7777777777777778 PFAM Integrase core domain 0.7777777777777778 - 0.7777777777777778 - 1.0 - 1.0 ko:K07497 0.7777777777777778 - 0.7777777777777778 - 0.7777777777777778 - 1.0 - 1.0 ko00000 0.7777777777777778 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001065_00121 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 0.7777777777777778 K07497:K07497; putative transposase 0.7777777777777778 none 1.0 0 0 0 470787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2054824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633060 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1154616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Hex)AFAPDVIIALGGGSAMDAGK MGYG000003504_01226 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-314|g__CAG-1435|s__CAG-1435 sp003537755|m__MGYG000003504 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003504_01226 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117234005 0 0 0 0 0 0 0 0 0 0 0 +(Hex)LSSGYKINR MGYG000002580_01396;MGYG000000136_01850;MGYG000000076_00961;MGYG000004039_00624;MGYG000004317_00523;MGYG000003694_02093;MGYG000000099_02202;MGYG000004317_00093;MGYG000002552_01183;MGYG000000489_01309;MGYG000001617_02963;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000000099_03212;MGYG000000205_00843;MGYG000000154_02141;MGYG000003422_01457;MGYG000002517_00135;MGYG000000417_00080;MGYG000000217_01135;MGYG000001141_01878;MGYG000000356_01643;MGYG000000398_01070;MGYG000003422_01458;MGYG000000187_02828;MGYG000001065_00070;MGYG000003215_01405;MGYG000002247_02078;MGYG000000562_01318;MGYG000000562_01835;MGYG000001637_00814;MGYG000000245_00974;MGYG000003694_00680;MGYG000000271_01499;MGYG000001186_01647;MGYG000004414_00337;MGYG000004831_00621;MGYG000000217_00038;MGYG000003694_03279;MGYG000001500_00161 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae 0.3488372093023256 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9534883720930233 - 0.8372093023255814 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.8837209302325582 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002580_01396 0.023255813953488372 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ICPL_13C(6))ADIIMILINDEK MGYG000000301_00839;MGYG000004735_00452;MGYG000000201_04066;MGYG000004087_02660;MGYG000001496_01234;MGYG000000271_00298;MGYG000002517_01587 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 0.42857142857142855 186801|Clostridia 1.0 EH 0.5714285714285714 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_00839 0.14285714285714285 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2718641 0 0 0 0 0 0 +(ICPL_13C(6))DTDKPFVMPVEDVFSITGR MGYG000000216_02406;MGYG000000171_02844;MGYG000000201_03875;MGYG000001338_03373;MGYG000000142_00171;MGYG000000212_03313;MGYG000004733_01211 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000216_02406 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ICPL_13C(6))GLEARLYMWEGDYAK MGYG000003697_00737;MGYG000002080_01611 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG3193@1|root,COG3193@2|Bacteria,4NKF2@976|Bacteroidetes,2G0TY@200643|Bacteroidia,4AVF2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_00737 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284379 0 337013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1382560 0 2482100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 202869 0 338610 0 0 0 0 0 0 0 0 0 0 0 +(ICPL_13C(6)2H(4))GLVTTIAWGLDGK MGYG000001315_01111;MGYG000004733_00600;MGYG000002059_01430;MGYG000000489_00188;MGYG000000038_01493;MGYG000002946_02679;MGYG000001698_01656;MGYG000000164_01754;MGYG000002274_01022;MGYG000000271_02110;MGYG000001338_01881;MGYG000002517_00259;MGYG000002186_01069;MGYG000000205_00108;MGYG000000187_00247;MGYG000001496_03285;MGYG000000489_01562;MGYG000000245_01078;MGYG000000249_01696;MGYG000002756_00504;MGYG000000389_02030;MGYG000000184_02616;MGYG000004087_02483;MGYG000001617_02316;MGYG000002517_00523;MGYG000000179_02171;MGYG000002105_01106;MGYG000000198_04024 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 0.2857142857142857 186801|Clostridia 1.0 F 0.5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01111 0.03571428571428571 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44918860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ICPL_13C(6)2H(4))ISKWNATSLEAR MGYG000000184_00682 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A luti|m__MGYG000000184 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_00682 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 929396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1030169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114136 0 0 0 0 0 0 0 0 +(ICPL_13C(6)2H(4))LAAADVNPDTR MGYG000000193_02120 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__KLE1615|s__KLE1615 sp900066985|m__MGYG000000193 1.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 - 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000193_02120 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02952:RP-S13, rpsM; small subunit ribosomal protein S13 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ICPL_13C(6)2H(4))LQSATLDDLGTAHQVR MGYG000004804_00243 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900759415|m__MGYG000004804 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4H29X@909932|Negativicutes 1.0 909932|Negativicutes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 - 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004804_00243 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ICPL_13C(6)2H(4))NLSNSSADVVDNIEK MGYG000002478_04317 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,2FMV2@200643|Bacteroidia,4AMM1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family 1.0 galE 1.0 - 1.0 5.1.3.2 1.0 ko:K01784 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00361,M00362,M00632 1.0 R00291,R02984 1.0 RC00289 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_04317 1.0 UDP-glucose 4-epimerase. uridine diphospho-galactose-4-epimerase. Also acts on UDP-2-deoxyglucose. UDP-alpha-D-glucose = UDP-alpha-D-galactose. 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K01784:galE, GALE; UDP-glucose 4-epimerase [EC:5.1.3.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 779816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 735902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ICPL_13C(6)2H(4))VEHFGRLGGIVFTPDEVLNALK MGYG000001489_03267;MGYG000002438_03197 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0674@1|root,COG0674@2|Bacteria,4NGYK@976|Bacteroidetes,2FM6R@200643|Bacteroidia,22WCE@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Catalyzes the coenzyme A-dependent oxidation of 3-methyl-2-oxobutanoate coupled to the reduction of ferredoxin producing S-(2-methylpropanoyl)-CoA 1.0 vorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00174 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFOR_II,POR_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001489_03267 0.5 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00174:korA, oorA, oforA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14406931 0 0 0 0 0 0 0 0 +(ICPL_2H(4))ADIIMILINDEK MGYG000000301_00839;MGYG000004735_00452;MGYG000000201_04066;MGYG000004087_02660;MGYG000001496_01234;MGYG000000271_00298;MGYG000002517_01587 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 0.42857142857142855 186801|Clostridia 1.0 EH 0.5714285714285714 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_00839 0.14285714285714285 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3141999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 936250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ISD_z+2_ion)EGALSETHSILQR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00135 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 303582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297724 0 178246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9428955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ISD_z+2_ion)EYQYFPFEPK MGYG000001313_02680 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0153@1|root,COG0153@2|Bacteria,4NE0C@976|Bacteroidetes,2FNGC@200643|Bacteroidia,4AKIZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Belongs to the GHMP kinase family. GalK subfamily 1.0 galK 1.0 - 1.0 2.7.1.6 1.0 ko:K00849 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00554,M00632 1.0 R01092 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_02680 1.0 galactokinase. - Part of the Leloir pathway for galactose metabolism.-!-The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine. alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+). 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K00849:galK; galactokinase [EC:2.7.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1970938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ISD_z+2_ion)GINPNAFDGR MGYG000000099_02389 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,268U3@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits 1.0 rplE 1.0 - 1.0 - 1.0 ko:K02931 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L5,Ribosomal_L5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_02389 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02931:RP-L5, MRPL5, rplE; large subunit ribosomal protein L5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ISD_z+2_ion)GSNGVIMITTK MGYG000002478_01871 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,4P0HT@976|Bacteroidetes,2FPW8@200643|Bacteroidia,4AT1I@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01871 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5895278 4270452 +(ISD_z+2_ion)NILVINC(Carbamidomethyl)GSSSLK MGYG000000233_01457 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,21XHV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_01457 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217140 0 0 0 0 0 0 0 1883554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1746755 0 0 0 0 2288151 0 0 343057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ISD_z+2_ion)QHPDLIDVPITGVGGIETWR MGYG000002528_01044 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0167@1|root,COG1146@1|root,COG0167@2|Bacteria,COG1146@2|Bacteria,1TRPI@1239|Firmicutes,24A0Z@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Dihydroorotate dehydrogenase 1.0 preA 1.0 - 1.0 1.3.1.1 1.0 ko:K17723 1.0 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 1.0 M00046 1.0 R00977,R01414,R11026 1.0 RC00072,RC00123 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHO_dh,Fer4_20,Fer4_21,Fer4_4,Fer4_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01044 1.0 dihydrouracil dehydrogenase (NAD(+)). - The enzyme was originally discovered in the uracil-fermenting bacterium, Clostridium uracilicum, which utilizes uracil and thymine as nitrogen and carbon sources for growth.-!-Since then the enzyme was found in additional organisms including Alcaligenes eutrophus, Pseudomonas strains and Escherichia coli. (1) 5,6-dihydrouracil + NAD(+) = H(+) + NADH + uracil. (2) 5,6-dihydrothymine + NAD(+) = H(+) + NADH + thymine. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|beta-Alanine metabolism|Pantothenate and CoA biosynthesis|Metabolic pathways 1.0 K17723:preA; dihydropyrimidine dehydrogenase (NAD+) subunit PreA [EC:1.3.1.1] 1.0 none 1.0 0 163645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222915 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 523109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ISD_z+2_ion)SSLGALQNRLEHTVANLDNVAENTQSAESR MGYG000004271_01770 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01770 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ISD_z+2_ion)VIMIEDVTTSGK MGYG000002992_01058;MGYG000002528_00495;MGYG000000140_00157;MGYG000000206_02791;MGYG000000301_01060;MGYG000002393_00122;MGYG000001374_01050;MGYG000000217_01922;MGYG000002279_02444;MGYG000002756_01770;MGYG000000028_01453;MGYG000001141_00854;MGYG000000187_01588 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,27UZH@189330|Dorea 0.3076923076923077 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002992_01058 0.07692307692307693 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00762:pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] 1.0 none 1.0 0 984926 0 0 0 0 0 0 0 0 0 0 0 0 1653985 0 0 0 0 794104 0 0 0 0 0 0 0 0 0 0 0 0 0 443226 0 0 0 0 0 3275672 0 0 0 0 0 0 0 0 0 0 0 0 889351 0 0 0 0 1654524 0 0 0 0 0 0 0 0 0 0 2254207 0 0 1381273 0 0 0 0 0 1776146 0 0 0 0 0 0 0 0 0 0 0 0 1352716 0 0 0 0 1140873 0 0 0 0 0 0 0 0 0 0 1052445 0 0 1306325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3370079 0 0 0 0 0 0 0 0 0 0 0 0 2024123 0 0 0 0 1367066 0 0 0 0 0 0 0 0 0 0 1557264 0 0 0 0 0 0 0 +(ISD_z+2_ion)VMIIEDVTTSGK MGYG000000179_05171 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,267V0@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_05171 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00762:pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1626184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ISD_z+2_ion)VNLCGGGFTGQSQALR MGYG000004748_03238;MGYG000002560_02422;MGYG000004479_00779;MGYG000000043_00067;MGYG000001599_02778;MGYG000000196_04089;MGYG000004185_02065;MGYG000004019_01937;MGYG000003681_02137;MGYG000002171_01962;MGYG000003367_01578;MGYG000002291_02395;MGYG000001780_01719;MGYG000004899_04130;MGYG000001787_00222;MGYG000001306_01211;MGYG000003693_02546;MGYG000001835_01928;MGYG000002281_00009;MGYG000000781_00884;MGYG000002455_03781;MGYG000001346_00647;MGYG000000243_02463;MGYG000000042_00637;MGYG000001783_00061;MGYG000001370_01952;MGYG000003363_02163 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0103@1|root,COG0103@2|Bacteria,4NNN1@976|Bacteroidetes,2FSGZ@200643|Bacteroidia,4AQR7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 1.0 rpsI 1.0 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004748_03238 0.037037037037037035 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02996:RP-S9, MRPS9, rpsI; small subunit ribosomal protein S9 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3385219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ISD_z+2_ion)VVVTGVEMFR MGYG000001234_01151;MGYG000000120_01190;MGYG000002854_00111;MGYG000000420_01950;MGYG000004847_01222;MGYG000001623_00993;MGYG000002837_02416;MGYG000002528_01098;MGYG000002901_00528;MGYG000000016_02519;MGYG000004285_00597;MGYG000004718_00646;MGYG000002563_00509;MGYG000004565_01266;MGYG000000262_00030;MGYG000000433_00368;MGYG000002563_00522;MGYG000001315_01207;MGYG000000177_01044;MGYG000004642_00846;MGYG000002290_01325;MGYG000002854_00124;MGYG000002234_01026 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,25QFW@186804|Peptostreptococcaceae 0.30434782608695654 186801|Clostridia 0.9565217391304348 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9565217391304348 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001234_01151 0.043478260869565216 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702117 0 0 0 0 0 0 688955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496465 423456 0 0 0 0 0 0 0 0 0 823345 0 370849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 884592 688116 0 0 0 0 0 0 0 0 0 896026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ISD_z+2_ion)WSNGDPVTANDFVYAWHR MGYG000000045_02091 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG4166@1|root,COG4166@2|Bacteria,2NPWR@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000045_02091 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788100 0 0 0 0 567438 0 0 0 0 856563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(ISD_z+2_ion)YKEAYELLTGK MGYG000003694_01732 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter faecis|m__MGYG000003694 1.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,2483I@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 SAICAR synthetase 1.0 purC 1.0 - 1.0 6.3.2.6 1.0 ko:K01923 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04591 1.0 RC00064,RC00162 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 SAICAR_synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01732 1.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase. SAICAR synthetase. Forms part of the purine biosynthesis pathway. 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate + ADP + 2 H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01923:purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Iminobiotin)AAEHVVGVAQGVSEDILADLR MGYG000000255_00995 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_00995 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 827259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331197 0 0 0 0 0 0 0 354221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162292 0 0 0 0 356100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1840778 0 0 0 0 497518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 393995 0 0 0 0 181386 0 0 766961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1401277 0 0 0 0 556998 +(Iminobiotin)TNCCCTIGLGGGK MGYG000002966_00993 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900551075|m__MGYG000002966 1.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,36ED1@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Dehydrogenase 1.0 dhaD 1.0 - 1.0 1.1.1.6 1.0 ko:K00005 1.0 ko00561,ko00640,ko01100,map00561,map00640,map01100 1.0 - 1.0 R01034,R10715,R10717 1.0 RC00029,RC00117,RC00670 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002966_00993 1.0 glycerol dehydrogenase. NAD-linked glycerol dehydrogenase. Also acts on 1,2-propanediol. glycerol + NAD(+) = dihydroxyacetone + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Propanoate metabolism|Metabolic pathways 1.0 K00005:gldA; glycerol dehydrogenase [EC:1.1.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1209883 0 0 0 0 593472 +(Iodoacetanilide)AAALQPGEVLLLENLR MGYG000000196_04506;MGYG000000013_01224;MGYG000003681_00986;MGYG000002549_02739;MGYG000001661_02348;MGYG000003922_03393;MGYG000004876_02584 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04506 0.14285714285714285 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 389600 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1365499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Iodoacetanilide)EIAEISEDKR MGYG000000255_01812;MGYG000000198_04915 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,21XI7@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 - 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01812 0.5 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4728621 0 0 0 0 0 0 2575945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2186146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Iodoacetanilide)FMAAIEAALEKGDVEAAK MGYG000002561_00509;MGYG000001313_03230 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002561_00509 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Iodoacetanilide)GITNKVSDVDISEFYR MGYG000000255_01008 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01008 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 832994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Iodoacetanilide)IAPVFTDDEDQSR MGYG000000179_05046 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_05046 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 99691 0 145641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307348 0 0 97683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19179450 0 6826365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8571042 0 7339615 0 0 20109453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Iodoacetanilide)LIEWVLWNSER MGYG000000243_02761 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1803@1|root,COG1803@2|Bacteria,4NQJ9@976|Bacteroidetes,2FPT5@200643|Bacteroidia,4ANEX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 methylglyoxal synthase 1.0 mgsA 1.0 - 1.0 4.2.3.3 1.0 ko:K01734 1.0 ko00640,ko01120,map00640,map01120 1.0 - 1.0 R01016 1.0 RC00424 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02761 1.0 methylglyoxal synthase. - Does not act on D-glyceraldehyde 3-phosphate.-!-Formerly EC 4.2.99.11. dihydroxyacetone phosphate = methylglyoxal + phosphate. 1.0 1.0 1.0 1.0 Propanoate metabolism|Microbial metabolism in diverse environments 1.0 K01734:mgsA; methylglyoxal synthase [EC:4.2.3.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10661698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Iodoacetanilide)LYDFLDSSK MGYG000004697_00401 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eubacterium_F|s__|m__MGYG000004697 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,25VKP@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004697_00401 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Vitamin B6 metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00831:serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 996169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Iodoacetanilide)SETFSTAADNQSEVTIHVLQGER MGYG000000196_01218 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,4ANVI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_01218 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Iodoacetanilide_13C(6))DKTVTENTR MGYG000000258_01582 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Ruminococcus_E|s__Ruminococcus_E bromii_B|m__MGYG000000258 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia 1.0 186801|Clostridia 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_01582 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 0 0 0 0 0 3749243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 787375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1058418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2995923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(LG-anhyropyrrole)INPESDLVEIVEIPTLK MGYG000001306_01353 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0504@1|root,COG0504@2|Bacteria,4NEWT@976|Bacteroidetes,2FMC4@200643|Bacteroidia,4AMIN@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates 1.0 pyrG 1.0 - 1.0 6.3.4.2 1.0 ko:K01937 1.0 ko00240,ko01100,map00240,map01100 1.0 M00052 1.0 R00571,R00573 1.0 RC00010,RC00074 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CTP_synth_N,GATase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_01353 1.0 CTP synthase (glutamine hydrolyzing). UTP--ammonia ligase. The enzyme contains three functionally distinct sites: an allosteric GTP-binding site, a glutaminase site where glutamine hydrolysis occurs (cf. EC 3.5.1.2), and the active site where CTP synthesis takes place.-!-The reaction proceeds via phosphorylation of UTP by ATP to give an activated intermediate 4-phosphoryl UTP and ADP.-!-Ammonia then reacts with this intermediate generating CTP and a phosphate.-!-The enzyme can also use ammonia from the surrounding solution. ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K01937:pyrG, CTPS; CTP synthase [EC:6.3.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(LG-anhyropyrrole)LDAIHDTVHEMAR MGYG000002517_02838;MGYG000002961_00635 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.5 186801|Clostridia 0.5 C 1.0 Rubrerythrin 1.0 rbr3A 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02838 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(LG-anhyropyrrole)VGIALFLSHLAHEGK MGYG000000196_01613;MGYG000000042_02438;MGYG000000243_00830;MGYG000000098_01886;MGYG000002478_00044 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1109@1|root,COG1109@2|Bacteria,4NG3H@976|Bacteroidetes,2FM6E@200643|Bacteroidia,4ANM1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 8.96 1.0 glmM 1.0 - 1.0 5.4.2.8 1.0 ko:K01840 1.0 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 1.0 M00114 1.0 R01818 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_01613 0.2 phosphomannomutase. phosphomannose mutase. alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01840:manB; phosphomannomutase [EC:5.4.2.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(LG-pyrrole)DLVLAPMMQGAVNYMHTGNR MGYG000000074_01125 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1834@1|root,COG1834@2|Bacteria,4NFQ7@976|Bacteroidetes,2FNG1@200643|Bacteroidia,22VJQ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01125 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8241855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13727568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2126201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Lys)NGGCGECQTSC(Carbamidomethyl)QSAC(Carbamidomethyl)K MGYG000004863_00663;MGYG000003961_01976 phylum d__Bacteria|p__Firmicutes_A 1.0 2EGRK@1|root,317VV@2|Bacteria,1U4MD@1239|Firmicutes,25N9S@186801|Clostridia,2N7T3@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Six-cysteine peptide SCIFF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SCIFF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004863_00663 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 930217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Lys)RTAVQQEINQLASEITR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00135 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Lys)TYAMQTVHGR MGYG000000243_01840 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,2FME7@200643|Bacteroidia,4AKME@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin 1.0 oorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00175 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01840 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00175:korB, oorB, oforB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Met-loss)MEALGM(Oxidation)IETK MGYG000002098_00283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01|s__|m__MGYG000002098 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,22HKK@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002098_00283 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2413967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Met-loss)MEALGMIETK MGYG000002098_00283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01|s__|m__MGYG000002098 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,22HKK@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002098_00283 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21671039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Met-loss+Acetyl)MAIADLDKQPDSVSSVLK MGYG000003372_02465;MGYG000002494_03392;MGYG000002535_01618 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 2D4RX@1|root,2SW2Q@2759|Eukaryota 0.6666666666666666 2759|Eukaryota 0.6666666666666666 S 0.6666666666666666 helix_turn_helix isocitrate lyase regulation 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 HTH_IclR,IclR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003372_02465 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2168386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2462786 0 1628753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Met-loss+Acetyl)MAKEKFER MGYG000003142_01865;MGYG000000196_03974;MGYG000003142_01879;MGYG000002528_01098;MGYG000001346_01533;MGYG000001630_01142;MGYG000001313_00097;MGYG000000243_01988;MGYG000003266_00392;MGYG000000236_01807;MGYG000003514_00785;MGYG000004763_01689;MGYG000001485_02164 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.38461538461538464 976|Bacteroidetes 0.5384615384615384 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9230769230769231 tuf 1.0 - 0.8461538461538461 - 1.0 ko:K02358 0.9230769230769231 - 0.9230769230769231 - 0.9230769230769231 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9230769230769231 - 0.9230769230769231 - 1.0 - 0.9230769230769231 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003142_01865 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 - 0.9230769230769231 K02358:tuf, TUFM; elongation factor Tu 0.9230769230769231 none 1.0 0 684239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1340723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Met-loss+Acetyl)MAKEKYER MGYG000003683_00887 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CYY7@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00887 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Met-loss+Acetyl)MSEQNNTEMAFQIQR MGYG000002494_02265;MGYG000002535_04413;MGYG000003372_03408 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1952@1|root,COG1952@2|Bacteria,1RI75@1224|Proteobacteria,1S62H@1236|Gammaproteobacteria,3WXY5@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 U 1.0 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA 1.0 secB 1.0 GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 1.0 - 1.0 ko:K03071 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044,ko03110 1.0 3.A.5 1.0 - 1.0 - 1.0 SecB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02265 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03071:secB; preprotein translocase subunit SecB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 956586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1204543 0 584898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Met-loss+Acetyl)MSKEKFER MGYG000001692_03322;MGYG000002535_04656;MGYG000003363_01661;MGYG000002506_03686;MGYG000002506_02966 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,3ZITI@590|Salmonella 0.8 1236|Gammaproteobacteria 0.8 J 1.0 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.8 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001692_03322 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 2306081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3801918 0 0 0 0 0 0 2108657 0 0 0 4202467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5647115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4365057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5830275 0 5511407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10027246 0 0 0 0 0 0 0 0 11029598 0 0 0 0 12054238 +(Met-loss+Acetyl)MSMSDDTHNSLSTGK MGYG000002494_01908 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0685@1|root,KOG0564@2759|Eukaryota 1.0 2759|Eukaryota 1.0 E 1.0 methylenetetrahydrofolate reductase (NAD(P)H) activity 1.0 MTHFR1 1.0 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.0 1.5.1.20,3.6.4.12 1.0 ko:K00297,ko:K10901 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko03440,ko03460,map00670,map00720,map01100,map01120,map01200,map01523,map03440,map03460 1.0 M00295,M00377,M00414 1.0 R01224,R07168 1.0 RC00081 1.0 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 1.0 - 1.0 - 1.0 - 1.0 BT1,DEAD,DUF1712,EamA,Helicase_C,Homoserine_dh,Hormone_recep,MTHFR,RecQ_Zn_bind,peroxidase,zf-C4 1.0 - 1.0 - 1.0 - 1.0 AA0 1.0 MGYG000002494_01908 1.0 methylenetetrahydrofolate reductase [NAD(P)H]. | DNA helicase. MTHFR. A flavoprotein (FAD).-!-The enzyme catalyzes the reversible conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, playing an important role in folate metabolism by regulating the distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis.-!-This enzyme, characterized from Protozoan parasites of the genus Leishmania, is unique among similar characterized eukaryotic enzymes in that it lacks the C-terminal allosteric regulatory domain (allowing it to catalyze a reversible reaction) and uses NADH and NADPH with equal efficiency under physiological conditions. cf. EC 1.5.1.53, EC 1.5.1.54, and EC 1.5.7.1.-!-Formerly EC 1.1.1.68, EC 1.1.1.171, EC 1.1.99.15 and EC 1.7.99.5. | DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA.-!-Some of them unwind duplex DNA with a 3' to 5' polarity, other show 5' to 3' polarity or unwind DNA in both directions.-!-Some helicases unwind DNA as well as RNA.-!-May be identical with EC 3.6.4.13. (1) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH. (2) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH. | ATP + H2O = ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Antifolate resistance|Homologous recombination|Fanconi anemia pathway 1.0 K00297:metF, MTHFR; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]|K10901:BLM, RECQL3, SGS1; bloom syndrome protein [EC:5.6.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2093754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Met-loss+Acetyl)MSNVIVKDNESLDSALR MGYG000000087_00069;MGYG000000255_00059 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 1.0 203691|Spirochaetes 1.0 L 1.0 PFAM Integrase core domain 1.0 - 1.0 - 1.0 - 1.0 ko:K07497 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000087_00069 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07497:K07497; putative transposase 1.0 none 1.0 881644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531165 0 0 0 0 0 0 0 0 0 0 753405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 414670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Met-loss+Acetyl)MSNVIVKDNESLDSALRR MGYG000000087_00069;MGYG000000255_00059 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG2801@1|root,COG2963@1|root,COG2801@2|Bacteria,COG2963@2|Bacteria,2J816@203691|Spirochaetes 1.0 203691|Spirochaetes 1.0 L 1.0 PFAM Integrase core domain 1.0 - 1.0 - 1.0 - 1.0 ko:K07497 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 HTH_21,HTH_Tnp_1,rve,rve_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000087_00069 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07497:K07497; putative transposase 1.0 none 1.0 980751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858672 0 0 0 0 0 0 0 0 0 0 497674 0 1279894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1532632 0 0 0 0 0 0 0 0 0 0 1695489 0 870404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 440804 0 0 0 0 0 0 0 0 0 0 671208 0 335467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 831248 0 0 0 0 0 0 0 0 0 0 1073052 0 431467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216384 0 0 0 0 0 0 0 0 0 0 2292709 0 +(Met-loss+Acetyl)MTAVENAAVSQEELDAK MGYG000001292_01825 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG1882@1|root,COG1882@2|Bacteria,2GTTT@201174|Actinobacteria,4CZ59@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 Pyruvate formate lyase-like 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bac_luciferase,Fer4_12,Gly_radical,PFL-like,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001292_01825 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 625192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Met-loss+Acetyl)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.1 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AASSESFGYNEDPIVSSDVIGMR MGYG000001157_00577 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540775|m__MGYG000001157 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001157_00577 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4661388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5242856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AAVEEGIIPGGGVAYIR MGYG000000170_00603 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900240235|m__MGYG000000170 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22UPC@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000170_00603 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2584432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AAVEEGIVPGGGVAYIR MGYG000001562_02467;MGYG000004469_00981;MGYG000003469_01417;MGYG000001302.1_02015;MGYG000003467_00265;MGYG000004658_01438;MGYG000000074_00757;MGYG000001546_00436;MGYG000000003_00613;MGYG000003279_00515 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22UPC@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000001562_02467 0.1 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2526331 0 0 0 0 0 0 0 0 0 0 0 2254615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AEDLKELYVLPENDLK MGYG000000198_05929 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,21ZAM@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_05929 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2117428 0 0 0 0 0 0 0 0 0 0 539678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 439271 0 0 0 0 0 0 0 0 0 0 1722852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AGADLLVLAYHR MGYG000000077_01037;MGYG000000142_02711;MGYG000004839_00803;MGYG000000187_00408;MGYG000002098_00381;MGYG000000078_00616;MGYG000004317_01742;MGYG000004055_01306;MGYG000000206_00137;MGYG000000018_00879;MGYG000002156_00398;MGYG000000562_00802;MGYG000000690_00596;MGYG000000262_02262;MGYG000000216_01929;MGYG000000146_01522;MGYG000002756_03331;MGYG000001658_00185;MGYG000000352_00144;MGYG000000356_02067;MGYG000000193_02344 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae 0.8571428571428571 186801|Clostridia 0.9523809523809523 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily 1.0 rfbB 1.0 - 1.0 4.2.1.46 0.9523809523809523 ko:K01710 0.9523809523809523 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 0.9523809523809523 M00793 0.9523809523809523 R06513 0.9523809523809523 RC00402 0.9523809523809523 ko00000,ko00001,ko00002,ko01000 0.9523809523809523 - 1.0 - 1.0 - 1.0 GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 GT2 0.7142857142857143 MGYG000000077_01037 0.047619047619047616 dTDP-glucose 4,6-dehydratase. - - dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. 0.9523809523809523 0.9523809523809523 0.9523809523809523 0.9523809523809523 Streptomycin biosynthesis|Polyketide sugar unit biosynthesis|Acarbose and validamycin biosynthesis|Biosynthesis of vancomycin group antibiotics 0.9523809523809523 K01710:rfbB, rmlB, rffG; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] 0.9523809523809523 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AGDDAAGLAISEK MGYG000001615_01518;MGYG000000152_01227;MGYG000001334_01184;MGYG000000198_00788;MGYG000001496_01497;MGYG000001615_02187;MGYG000000150_03902;MGYG000000099_02202;MGYG000001617_02963;MGYG000000099_03212;MGYG000001311_05635;MGYG000001504_03254;MGYG000000024_00320;MGYG000002949_03375;MGYG000000090_01557;MGYG000001334_01190;MGYG000001615_01520;MGYG000003215_01405;MGYG000001496_01502;MGYG000000179_04407;MGYG000001496_01500;MGYG000002421_00363;MGYG000001470_01217;MGYG000000264_02727;MGYG000004541_00237;MGYG000000915_01790;MGYG000001571_00647;MGYG000000323_01374;MGYG000001470_04423;MGYG000004831_00621;MGYG000001470_04044;MGYG000001500_00161;MGYG000000152_03627 domain d__Bacteria 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,21Z1P@1506553|Lachnoclostridium 0.30303030303030304 186801|Clostridia 0.7272727272727273 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9696969696969697 hag 0.8484848484848485 - 0.7272727272727273 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.6060606060606061 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001615_01518 0.030303030303030304 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7703081 0 0 0 0 0 0 0 0 6686324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AGGYNMVSSVNDTYR MGYG000000217_02614 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Acetatifactor|s__Acetatifactor sp900066565|m__MGYG000000217 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000217_02614 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3899843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AKEEFVR MGYG000002293_00521;MGYG000003697_01485 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0050@1|root,COG0050@2|Bacteria,4P1C5@976|Bacteroidetes,2FX1Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00521 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 396767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287738 0 0 0 0 0 0 0 193128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 349840 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29133985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14589689 0 21035984 0 0 0 0 21285956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AKEKFDR MGYG000004756_01173;MGYG000001415_02515;MGYG000002438_02321;MGYG000004658_01205;MGYG000004288_00862;MGYG000002972_00178;MGYG000003516_01606;MGYG000003542_01415;MGYG000001562_01075;MGYG000000045_02616;MGYG000000254_02569;MGYG000000074_01773;MGYG000003279_00951;MGYG000001470_03722;MGYG000000044_01721;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000000223_03134;MGYG000001400_03001 life d__Bacteria 0.9474 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 0.47368421052631576 976|Bacteroidetes 0.631578947368421 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.8421052631578947 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.9473684210526315 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004756_01173 0.05263157894736842 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64335 0 0 0 0 0 0 0 25703 0 232346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199776 0 0 0 0 0 0 0 590718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1479578 0 0 0 0 0 0 0 0 0 37064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444840 0 0 0 0 0 0 0 80052 0 14131 0 0 0 0 0 0 0 +(Methyl)AKEKFER MGYG000000042_01421;MGYG000002106_00224;MGYG000001524_01606;MGYG000001630_01142;MGYG000002485_02622;MGYG000004893_01944;MGYG000004893_00932;MGYG000003460_01161;MGYG000003155_00314;MGYG000001925_01419;MGYG000000273_00431;MGYG000001701_00473;MGYG000004763_01689;MGYG000003681_02037;MGYG000001384_04567;MGYG000001464_00103;MGYG000002281_02290;MGYG000003185_01074;MGYG000003992_01709;MGYG000003142_01879;MGYG000002528_01098;MGYG000001313_00097;MGYG000000013_02251;MGYG000003266_00392;MGYG000003583_01411;MGYG000002455_03884;MGYG000000348_00283;MGYG000003628_01000;MGYG000001485_02164;MGYG000000034_01346;MGYG000001141_02439;MGYG000002930_00867;MGYG000003142_01865;MGYG000000196_03974;MGYG000003375_00698;MGYG000004573_00004;MGYG000001661_02666;MGYG000003851_00676;MGYG000002762_01733;MGYG000000121_02189;MGYG000001789_00154;MGYG000001567_01738;MGYG000000182_00585;MGYG000000054_03933;MGYG000000236_01807;MGYG000000098_02017;MGYG000002291_02272;MGYG000003185_01053;MGYG000002556_01332;MGYG000000036_01380;MGYG000000445_01370;MGYG000001346_01533;MGYG000000243_01988;MGYG000001780_03476;MGYG000002540_03367;MGYG000001646_01118;MGYG000003073_01160;MGYG000003514_00785;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.23728813559322035 976|Bacteroidetes 0.4915254237288136 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9830508474576272 tuf 1.0 - 0.847457627118644 - 1.0 ko:K02358 0.9830508474576272 - 0.9830508474576272 - 0.9830508474576272 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9830508474576272 - 0.9830508474576272 - 1.0 - 0.9491525423728814 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.01694915254237288 - - - - 1.0 1.0 1.0 1.0 - 0.9830508474576272 K02358:tuf, TUFM; elongation factor Tu 0.9830508474576272 none 1.0 1323520 5014016 761927 1265284 4936830 613296 414322 1132323 794009 1238467 976466 1227882 1565935 2621112 965248 1036846 1558673 794050 949648 39971 1104889 422472 480844 1479437 1206540 938370 1182932 326152 727697 970637 8537718 647577 3205418 791620 1894943 622421 1669135 2715062 908867 3907080 1684027 498600 5398220 8838983 1169784 735151 190700 1422349 3426961 1974518 2402947 2179464 985939 9904334 3871971 1086867 2809866 349682 2431192 10281859 2658159 7454875 7229375 363285 663385 899365 9291523 1484799 751668 1666656 2130348 621762 403028 649443 603941 6755236 1602596 647035 275197 339188 246755 569800 641506 423726 186867 597099 782571 168391 553032 307474 223220 462286 1715003 31691 252781 255912 301933 236180 403926 1182713 462102 2391026 336570 319007 162210 207483 448548 224721 414071 289829 674558 498277 220632 241743 271500 0 1022074 371733 687260 770099 580463 658365 2373308 281029 3448333 2514002 3830141 756495 479739 1492526 171339 2129966 967808 166217 2601335 341549 1146627 510025 722565 882281 96311 3356769 98162 187478 1101393 538305 394755 119194 587752 958733 1183003 537927 3894783 3732409 701738 707887 2842788 5362876 457995 3438292 5848879 246467 910166 1233258 3389820 565523 1880784 6319160 5586806 4229669 503851 7264948 670582 620048 4049470 923990 1697498 4852755 915206 0 572354 2427318 260906 646269 796461 774549 13739183 609976 5680830 401707 +(Methyl)AKEQFQR MGYG000001881_00748 genome d__Bacteria|p__Verrucomicrobiota|c__Verrucomicrobiae|o__Verrucomicrobiales|f__Akkermansiaceae|g__Akkermansia|s__Akkermansia muciniphila_A|m__MGYG000001881 1.0 COG0050@1|root,COG0050@2|Bacteria,46SFG@74201|Verrucomicrobia,2ITQE@203494|Verrucomicrobiae 1.0 203494|Verrucomicrobiae 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001881_00748 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AKTETHIPAVIDTAEALEAK MGYG000000133_00993;MGYG000000301_01128 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00993 0.5 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 84362 0 0 0 0 0 0 0 0 0 0 0 0 56321 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71096 322306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2116302 1929282 2169706 0 0 2399104 0 0 0 0 0 0 2598604 0 1458987 2135995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2298380 0 0 1405093 0 0 +(Methyl)ALVPMVIEQTSR MGYG000003372_00321;MGYG000002535_03209;MGYG000002534_01240;MGYG000002494_00469 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,3WVQ6@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 OU 1.0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins 1.0 clpP 1.0 GO:0000502,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017171,GO:0019538,GO:0019899,GO:0030163,GO:0031597,GO:0032991,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051117,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 1.0 3.4.21.92 1.0 ko:K01358 1.0 ko04112,ko04212,map04112,map04212 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 CLP_protease 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003372_00321 0.25 endopeptidase Clp. protease Ti. Belongs to peptidase family S14. Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs). 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter|Longevity regulating pathway - worm 1.0 K01358:clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] 1.0 none 1.0 0 0 432363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3966508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4856959 0 0 0 0 0 0 0 418394 0 0 0 394366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 526129 0 0 0 0 0 0 0 0 0 0 0 490196 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)ASNLLYTR MGYG000002494_00829 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0783@1|root,COG0783@2|Bacteria,1RAC5@1224|Proteobacteria,1RR4N@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 P 1.0 During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction 1.0 dps 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005623,GO:0006950,GO:0008150,GO:0008199,GO:0009289,GO:0009295,GO:0009605,GO:0009991,GO:0031667,GO:0042594,GO:0042802,GO:0042995,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0097159,GO:1901363 1.0 - 1.0 ko:K04047 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03036 1.0 - 1.0 - 1.0 - 1.0 Ferritin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00829 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04047:dps; starvation-inducible DNA-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1796961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)ATGEVMAIGR MGYG000000335_00337 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Enterococcaceae|g__Enterococcus_G|s__Enterococcus_G italicus|m__MGYG000000335 1.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli,4AZM7@81852|Enterococcaceae 1.0 91061|Bacilli 1.0 EF 1.0 carbamoyl-phosphate synthetase ammonia chain 1.0 carB 1.0 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000335_00337 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01955:carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1211516 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AVAGVMNIETK MGYG000000074_02206 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG3590@1|root,COG3590@2|Bacteria,4NEYB@976|Bacteroidetes,2FP7Y@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 O 1.0 Peptidase family M13 1.0 pepO 1.0 - 1.0 3.4.24.71 1.0 ko:K01415,ko:K07386 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002,ko04147 1.0 - 1.0 - 1.0 - 1.0 Peptidase_M13,Peptidase_M13_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02206 1.0 endothelin-converting enzyme 1. ECE-1. Phosphoramidon-sensitive.-!-Belongs to peptidase family M13. Hydrolysis of the 21-Trp-|-Val-22 bond in big endothelin to form endothelin 1. 1.0 1.0 1.0 1.0 - 1.0 K01415:ECE; endothelin-converting enzyme [EC:3.4.24.71]|K07386:pepO; putative endopeptidase [EC:3.4.24.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1629959 0 0 +(Methyl)AVEAVDEC(Carbamidomethyl)VGK MGYG000003684_05297;MGYG000000249_01356 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,27JMY@186928|unclassified Lachnospiraceae 0.5 186801|Clostridia 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 - 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Metalloenzyme,PglZ,Phosphodiest,iPGM_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003684_05297 0.5 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K15633:gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AVNTAVEAVK MGYG000003937_00155 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3WGUG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003937_00155 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AVSAKDVMELR MGYG000003937_00036 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_00036 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AVVGANWGDEGKGK MGYG000000171_01836;MGYG000000515_02290;MGYG000004785_00710;MGYG000000200_00992;MGYG000002528_02635;MGYG000002202_00641;MGYG000000136_00460;MGYG000000213_00509;MGYG000003324_01888;MGYG000004039_01400;MGYG000001338_02654;MGYG000000201_00874;MGYG000004593_02178;MGYG000004735_01537;MGYG000003425_00268;MGYG000000245_00501;MGYG000004719_01729;MGYG000000133_00154;MGYG000000184_00060;MGYG000000018_01545;MGYG000001607_00542;MGYG000000212_03119;MGYG000001652_00002;MGYG000004697_01453;MGYG000000031_02099;MGYG000000142_01890;MGYG000000251_00296;MGYG000000141_03421;MGYG000003702_00960;MGYG000004740_00439;MGYG000000389_00666;MGYG000002517_01833;MGYG000004733_01110;MGYG000002945_01173;MGYG000002234_01353;MGYG000002298_00432;MGYG000000404_00404;MGYG000000216_02589;MGYG000003422_00451 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3XYKX@572511|Blautia 0.48717948717948717 186801|Clostridia 1.0 F 1.0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP 1.0 purA 1.0 - 1.0 6.3.4.4 1.0 ko:K01939 1.0 ko00230,ko00250,ko01100,map00230,map00250,map01100 1.0 M00049 1.0 R01135 1.0 RC00458,RC00459 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Adenylsucc_synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_01836 0.02564102564102564 adenylosuccinate synthase. succinoadenylic kinosynthetase. - GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01939:purA, ADSS; adenylosuccinate synthase [EC:6.3.4.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 882817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)AVVTGVEMFR MGYG000000323_00619;MGYG000000277_00173;MGYG000001558_01002;MGYG000004789_00520 order d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,42CX2@671232|Streptococcus anginosus group 0.5 91061|Bacilli 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 1.0 - 1.0 ko:K02358,ko:K15771 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000323_00619 0.25 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K02358:tuf, TUFM; elongation factor Tu|K15771:ganP, mdxF; arabinogalactan oligomer / maltooligosaccharide transport system permease protein 1.0 none 1.0 754932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 826004 0 0 0 0 0 0 0 0 0 0 391064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 345577 0 0 0 0 0 0 0 0 0 0 231565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485986 0 0 0 0 0 0 0 0 0 0 362557 0 +(Methyl)DALGMIETK MGYG000000150_00816;MGYG000000179_01371;MGYG000000198_01506;MGYG000000150_00833 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 0.75 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 0.75 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00816 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12028563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22225482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DASATALYGSR MGYG000003922_01771;MGYG000000348_01754;MGYG000001780_01242;MGYG000001313_00412;MGYG000001346_02561;MGYG000003362_02386;MGYG000003533_00526;MGYG000001655_02726;MGYG000001345_04490;MGYG000000105_01162;MGYG000000098_00457;MGYG000002171_00691;MGYG000004876_03126;MGYG000001780_03810;MGYG000002478_01858;MGYG000004588_02518;MGYG000003202_01776;MGYG000000013_04510;MGYG000002281_04203;MGYG000000183_04381;MGYG000001346_02568;MGYG000001641_01324;MGYG000004876_02392;MGYG000003498_00420;MGYG000002960_00779;MGYG000001780_00781;MGYG000003362_01220;MGYG000003697_02404;MGYG000004763_00489;MGYG000000168_01851;MGYG000001787_00133;MGYG000001345_03710;MGYG000001346_02291;MGYG000000437_00933;MGYG000000168_03318;MGYG000000673_00330;MGYG000004748_02928;MGYG000000196_00461;MGYG000003493_01627;MGYG000004823_00190;MGYG000000354_01804;MGYG000002478_01871;MGYG000004763_00494;MGYG000004876_03105;MGYG000003363_01827;MGYG000000196_03064;MGYG000000224_00771;MGYG000003367_00895;MGYG000002721_00156;MGYG000002478_00956;MGYG000004876_02902;MGYG000001661_00787;MGYG000001780_00996;MGYG000004797_01968;MGYG000000196_03113;MGYG000004561_00722;MGYG000001337_03660;MGYG000004797_00001;MGYG000004763_01369;MGYG000004876_02476;MGYG000004479_01532;MGYG000004464_01616;MGYG000000354_00270;MGYG000004876_00176;MGYG000003922_02156;MGYG000001345_04437;MGYG000001345_04559;MGYG000002478_00565;MGYG000000224_01718;MGYG000003493_02187;MGYG000001661_01127;MGYG000001313_01021;MGYG000000196_00132;MGYG000004899_00292;MGYG000001789_00592;MGYG000004495_02402;MGYG000001433_00908;MGYG000003223_00188;MGYG000000236_00420;MGYG000000183_02560;MGYG000000013_00507;MGYG000002455_01818;MGYG000004797_01501;MGYG000001378_02925;MGYG000000243_02340;MGYG000003922_01732;MGYG000001780_02437;MGYG000001783_00603;MGYG000003423_01221;MGYG000002293_02867;MGYG000003363_02178;MGYG000001780_02820;MGYG000002478_00743;MGYG000000825_01952;MGYG000000781_00147;MGYG000003460_00442;MGYG000000105_01229;MGYG000003233_02240;MGYG000001789_02867;MGYG000002293_02874;MGYG000001345_01594;MGYG000004464_01003;MGYG000002556_00559;MGYG000004797_01285;MGYG000004797_01842;MGYG000004876_02563;MGYG000003164_00175;MGYG000002905_01072;MGYG000002561_01649 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia,4ANGT@815|Bacteroidaceae 0.21100917431192662 976|Bacteroidetes 0.9908256880733946 P 0.9174311926605505 TonB-linked outer membrane protein, SusC RagA family 0.7064220183486238 - 0.7064220183486238 - 0.9541284403669725 - 1.0 - 0.6055045871559633 - 1.0 - 1.0 - 1.0 - 1.0 - 0.6055045871559633 - 0.6055045871559633 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.7981651376146789 - 1.0 - 1.0 - 1.0 - 0.9724770642201835 MGYG000003922_01771 0.009174311926605505 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 0.6055045871559633 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DATMAQLGR MGYG000000201_03110;MGYG000000806_01492;MGYG000003012_02207 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000201_03110 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1485340 0 0 0 0 0 +(Methyl)DFAENEVKPLAAEIDEEERFPMETVEK MGYG000002794_01608;MGYG000002720_01506 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2N683@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Psort location Cytoplasmic, score 9.97 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_01608 0.5 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 2149254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1249924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DFLLDMSDAGK MGYG000000171_02044 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3XYWE@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_02044 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1072756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DFLLSEVR MGYG000004718_01473;MGYG000000016_02335 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,36EA6@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 - 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_10,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000004718_01473 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1263777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DGAATAIYGSR MGYG000002438_02058 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,4NDXS@976|Bacteroidetes,2G0KF@200643|Bacteroidia,22XIH@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02058 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DGEDPGYTLYDLSER MGYG000002515_02735;MGYG000002506_00791;MGYG000002323_02099;MGYG000002506_03156;MGYG000002515_01515;MGYG000002323_00193 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,1RNSQ@1236|Gammaproteobacteria,3XMMA@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Converts glutamate to gamma-aminobutyrate (GABA), consuming one intracellular proton in the reaction. The gad system helps to maintain a near-neutral intracellular pH when cells are exposed to extremely acidic conditions. The ability to survive transit through the acidic conditions of the stomach is essential for successful colonization of the mammalian host by commensal and pathogenic bacteria 1.0 gadB 0.6666666666666666 GO:0003674,GO:0003824,GO:0004351,GO:0006873,GO:0006885,GO:0008150,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019725,GO:0030003,GO:0030004,GO:0030641,GO:0042592,GO:0045852,GO:0048878,GO:0050801,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 1.0 4.1.1.15 1.0 ko:K01580 1.0 ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940 1.0 M00027 1.0 R00261,R00489,R01682,R02466 1.0 RC00299 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECUMN_1333.ECUMN_1747,iUTI89_1310.UTI89_C1707,ic_1306.c1922 0.6666666666666666 Pyridoxal_deC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_02735 0.16666666666666666 glutamate decarboxylase. L-glutamate 1-carboxy-lyase. The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate. H(+) + L-glutamate = 4-aminobutanoate + CO2. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|beta-Alanine metabolism|Taurine and hypotaurine metabolism|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Quorum sensing|GABAergic synapse|Type I diabetes mellitus 1.0 K01580:E4.1.1.15, gadB, gadA, GAD; glutamate decarboxylase [EC:4.1.1.15] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DGWKLPDMPR MGYG000002218_00631;MGYG000000074_01657;MGYG000000174_02762 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,22ZVD@171551|Porphyromonadaceae 0.6666666666666666 976|Bacteroidetes 0.6666666666666666 S 0.6666666666666666 Oxidoreductase family, NAD-binding Rossmann fold 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal 0.6666666666666666 - 1.0 GH109 1.0 - 1.0 - 1.0 MGYG000002218_00631 0.3333333333333333 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DGWRLPDMPR MGYG000001378_04108;MGYG000000013_01888 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,4AP35@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tat pathway signal sequence domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal 1.0 - 1.0 GH109 1.0 - 1.0 - 1.0 MGYG000001378_04108 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1462264 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DIALAYASGIGAGR MGYG000000022_01738;MGYG000004679_00185;MGYG000002641_01737;MGYG000000636_00571;MGYG000001300_02737;MGYG000003899_01538;MGYG000000039_02617;MGYG000002545_01021;MGYG000002651_01532;MGYG000002610_02042;MGYG000003291_01288 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3WGY4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01738 0.09090909090909091 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 708248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596018 0 +(Methyl)DILSSVFR MGYG000004797_01140 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia,4ANV3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 ATPase histidine kinase DNA gyrase B HSP90 domain protein 1.0 htpG 1.0 - 1.0 - 1.0 ko:K04079 1.0 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HATPase_c_3,HSP90 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01140 1.0 - - - - 1.0 1.0 1.0 1.0 Protein processing in endoplasmic reticulum|PI3K-Akt signaling pathway|Necroptosis|Antigen processing and presentation|NOD-like receptor signaling pathway|Plant-pathogen interaction|IL-17 signaling pathway|Th17 cell differentiation|Progesterone-mediated oocyte maturation|Estrogen signaling pathway|Pathways in cancer|Prostate cancer|Fluid shear stress and atherosclerosis 1.0 K04079:HSP90A, htpG; molecular chaperone HtpG 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DIQINIFEVK MGYG000001345_04705;MGYG000000029_02795;MGYG000001056_01155;MGYG000000196_03995;MGYG000000236_01781;MGYG000000243_01965;MGYG000001346_01513;MGYG000003697_01462;MGYG000001378_05021;MGYG000001337_03883;MGYG000000054_03864;MGYG000002080_00547;MGYG000000224_00470;MGYG000002293_00499;MGYG000003681_02057;MGYG000001370_01701;MGYG000002834_00446;MGYG000002549_02919;MGYG000003363_02285 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0092@1|root,COG0092@2|Bacteria,4NE9F@976|Bacteroidetes,2FMYX@200643|Bacteroidia,22W3B@171551|Porphyromonadaceae 0.7368421052631579 976|Bacteroidetes 1.0 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 1.0 rpsC 1.0 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02982 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_04705 0.05263157894736842 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02982:RP-S3, rpsC; small subunit ribosomal protein S3 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858034 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DIVAYAAER MGYG000000053_01764 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp002358415|m__MGYG000000053 1.0 COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,2FNAR@200643|Bacteroidia,4AKUS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Glycosyl hydrolase family 20, catalytic domain protein 1.0 - 1.0 - 1.0 3.2.1.52 1.0 ko:K12373 1.0 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 1.0 M00079 1.0 R00022,R06004,R11316 1.0 RC00049 1.0 ko00000,ko00001,ko00002,ko01000,ko03110 1.0 - 1.0 GH20 1.0 - 1.0 CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b 1.0 3.2.1.52|3.2.1.- 1.0 GH20 1.0 GH20 1.0 GH20 1.0 MGYG000000053_01764 1.0 beta-N-acetylhexosaminidase. N-acetyl-beta-glucosaminidase. Acts on N-acetylglucosides and N-acetylgalactosides.-!-Formerly EC 3.2.1.29 and EC 3.2.1.30. Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. 1.0 1.0 1.0 1.0 Other glycan degradation|Various types of N-glycan biosynthesis|Amino sugar and nucleotide sugar metabolism|Glycosaminoglycan degradation|Glycosphingolipid biosynthesis - globo and isoglobo series|Glycosphingolipid biosynthesis - ganglio series|Metabolic pathways|Lysosome 1.0 K12373:HEXA_B; hexosaminidase [EC:3.2.1.52] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1376800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DLEADFLK MGYG000001364_00421;MGYG000000029_02970;MGYG000001306_01781;MGYG000000442_00741;MGYG000002171_00856;MGYG000001835_00781;MGYG000000243_00367;MGYG000003693_03255;MGYG000001750_00740;MGYG000002549_01442;MGYG000001599_02900 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,2FMET@200643|Bacteroidia,4AKSS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001364_00421 0.09090909090909091 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Vitamin B6 metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00831:serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2403625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DLPAFIIK MGYG000000201_02693;MGYG000001315_00492;MGYG000002994_00468;MGYG000001622_03187;MGYG000002186_00606;MGYG000000171_02133;MGYG000002966_03863;MGYG000000050_02427;MGYG000001439_01955;MGYG000001338_01256;MGYG000000184_00355;MGYG000001379_01879;MGYG000000262_00002 domain d__Bacteria 1.0 COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,3XZ23@572511|Blautia 0.46153846153846156 186801|Clostridia 0.9230769230769231 M 1.0 UDP-galactopyranose mutase 0.5384615384615384 glf 1.0 - 1.0 5.4.99.9 1.0 ko:K01854 1.0 ko00052,ko00520,map00052,map00520 1.0 - 1.0 R00505,R09009 1.0 RC00317,RC02396 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 GLF,NAD_binding_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_02693 0.07692307692307693 UDP-galactopyranose mutase. - - UDP-alpha-D-galactose = UDP-alpha-D-galactofuranose. 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism 1.0 K01854:glf; UDP-galactopyranose mutase [EC:5.4.99.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1181473 0 0 0 0 0 +(Methyl)DLYKNEIMDAMTKK MGYG000000142_02055 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,3WGYQ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits 1.0 rplE 1.0 - 1.0 - 1.0 ko:K02931 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L5,Ribosomal_L5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_02055 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02931:RP-L5, MRPL5, rplE; large subunit ribosomal protein L5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DMAEKVDAATK MGYG000002478_01081 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01081 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2465412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1996737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DMGHEVVEQFYEPDQLGK MGYG000002156_00958 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550585|m__MGYG000002156 1.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,2N6Y5@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 EH 1.0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002156_00958 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1269105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DTNLSKKDVEAVLK MGYG000000031_02074;MGYG000000142_01875;MGYG000000216_00603 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3Y0HQ@572511|Blautia 1.0 186801|Clostridia 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hup 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_02074 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)DVTLTYQLPK MGYG000001783_00567 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900551065|m__MGYG000001783 1.0 COG1629@1|root,COG3188@1|root,COG1629@2|Bacteria,COG3188@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4ANM7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 NPU 1.0 Psort location OuterMembrane, score 9.49 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001783_00567 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3184705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)EGLFIDVTAR MGYG000002203_01195 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__|m__MGYG000002203 1.0 COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002203_01195 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 813193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5085121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)EGNGSNPVR MGYG000000054_03245;MGYG000000196_02028;MGYG000000029_01424;MGYG000001378_01103 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0605@1|root,COG0605@2|Bacteria,4NDZ4@976|Bacteroidetes,2FNA0@200643|Bacteroidia,4AM34@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems 1.0 sodB 1.0 - 1.0 1.15.1.1 1.0 ko:K04564 1.0 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Sod_Fe_C,Sod_Fe_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000054_03245 0.25 superoxide dismutase. - - 2 H(+) + 2 superoxide = H2O2 + O2. 1.0 1.0 1.0 1.0 MAPK signaling pathway - fly|FoxO signaling pathway|Peroxisome|Longevity regulating pathway|Longevity regulating pathway - worm|Longevity regulating pathway - multiple species|Huntington disease 1.0 K04564:SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1061543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)EVASEKYPAMK MGYG000000243_00044 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3525@1|root,COG3525@2|Bacteria,4NE08@976|Bacteroidetes,2FNAR@200643|Bacteroidia,4AKUS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Glycosyl hydrolase family 20, catalytic domain protein 1.0 - 1.0 - 1.0 3.2.1.52 1.0 ko:K12373 1.0 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 1.0 M00079 1.0 R00022,R06004,R11316 1.0 RC00049 1.0 ko00000,ko00001,ko00002,ko01000,ko03110 1.0 - 1.0 GH20 1.0 - 1.0 CHB_HEX_C_1,F5_F8_type_C,Fn3_assoc,Glyco_hydro_20,Glyco_hydro_20b 1.0 3.2.1.52|3.2.1.- 1.0 GH20 1.0 GH20 1.0 GH20 1.0 MGYG000000243_00044 1.0 beta-N-acetylhexosaminidase. N-acetyl-beta-glucosaminidase. Acts on N-acetylglucosides and N-acetylgalactosides.-!-Formerly EC 3.2.1.29 and EC 3.2.1.30. Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. 1.0 1.0 1.0 1.0 Other glycan degradation|Various types of N-glycan biosynthesis|Amino sugar and nucleotide sugar metabolism|Glycosaminoglycan degradation|Glycosphingolipid biosynthesis - globo and isoglobo series|Glycosphingolipid biosynthesis - ganglio series|Metabolic pathways|Lysosome 1.0 K12373:HEXA_B; hexosaminidase [EC:3.2.1.52] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1099624 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)EVELADAYQNTGAQLVK MGYG000004876_02137;MGYG000001313_00852;MGYG000003363_02977;MGYG000000224_01773;MGYG000000105_03063;MGYG000001661_02480;MGYG000003681_02583;MGYG000001370_00105;MGYG000001346_02504 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004876_02137 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1544011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)EVIC(Carbamidomethyl)EIGYDSK MGYG000000262_02728;MGYG000000077_00332 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,25V3W@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme 1.0 - 1.0 - 1.0 2.5.1.6 1.0 ko:K00789 1.0 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 1.0 M00034,M00035,M00368,M00609 1.0 R00177,R04771 1.0 RC00021,RC01211 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02728 0.5 methionine adenosyltransferase. S-adenosylmethionine synthetase. Formerly EC 2.4.2.13. ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L- methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00789:metK, MAT; S-adenosylmethionine synthetase [EC:2.5.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1303589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 883388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)EVTMQVK MGYG000000997_00886;MGYG000002963_04226;MGYG000000484_00676;MGYG000002098_01458;MGYG000004839_02458;MGYG000004271_02055;MGYG000002025_02130;MGYG000004884_01557;MGYG000000271_00295;MGYG000000268_00625;MGYG000002989_00657;MGYG000001658_01867;MGYG000000135_03501;MGYG000004735_02785;MGYG000001319_00742;MGYG000004712_00508;MGYG000000140_00956;MGYG000000245_00417;MGYG000001748_02093;MGYG000004891_01762;MGYG000000242_00062;MGYG000002517_01841;MGYG000000078_01452;MGYG000000356_00231 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 O 1.0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter 1.0 groS 1.0 - 1.0 - 1.0 ko:K04078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 Cpn10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_00886 0.041666666666666664 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04078:groES, HSPE1; chaperonin GroES 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2956962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3199425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2713887 2770669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)FDNAAEYTVGQEIK MGYG000001338_02807;MGYG000000200_01113;MGYG000000184_01172 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3XZ95@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit 1.0 rplC 1.0 - 1.0 - 1.0 ko:K02906 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02807 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02906:RP-L3, MRPL3, rplC; large subunit ribosomal protein L3 1.0 none 1.0 866927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 837347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 677907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)FGLADAGNIYGR MGYG000001300_02567;MGYG000001642_00033;MGYG000000280_02177;MGYG000000185_00279;MGYG000002978_00618;MGYG000002651_00281;MGYG000004087_02957;MGYG000002279_01466;MGYG000003486_01767;MGYG000004733_02577;MGYG000002298_00566;MGYG000002274_02337;MGYG000000252_02565;MGYG000000090_02004;MGYG000003266_00234;MGYG000000028_02056;MGYG000001315_02833;MGYG000002775_00932;MGYG000003361_00996;MGYG000000142_03199;MGYG000004740_00564;MGYG000001502_02222;MGYG000002445_01002;MGYG000000383_00104;MGYG000002040_00064;MGYG000001086_01260;MGYG000001567_00737;MGYG000001737_00599;MGYG000004519_00910;MGYG000000693_01345;MGYG000000212_00356;MGYG000000213_02746;MGYG000002272_02328;MGYG000000031_03298;MGYG000004681_00802;MGYG000002528_02771;MGYG000000195_01901;MGYG000000146_02288;MGYG000001456.1_01574;MGYG000000171_00165;MGYG000001338_01027;MGYG000000100_00277;MGYG000001303_02138;MGYG000002545_01885;MGYG000000291_00793;MGYG000000269_00514;MGYG000001636_01145;MGYG000000216_02897;MGYG000000038_00531;MGYG000002641_02488;MGYG000002050_00805;MGYG000002312_02592;MGYG000000140_01570;MGYG000002992_00682;MGYG000002065_00609;MGYG000003291_00536;MGYG000004679_00587;MGYG000000022_02103;MGYG000001645_01495;MGYG000003891_00287;MGYG000000164_02014;MGYG000001779_00982;MGYG000002919_00234;MGYG000002619_00737 domain d__Bacteria 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia 0.296875 186801|Clostridia 0.609375 E 0.890625 Psort location Cytoplasmic, score 9.98 0.328125 metY 0.546875 - 1.0 2.5.1.49 0.890625 ko:K01740 0.890625 ko00270,ko01100,map00270,map01100 0.890625 - 1.0 R01287,R04859 0.890625 RC00020,RC02821,RC02848 0.890625 ko00000,ko00001,ko01000 0.890625 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 0.609375 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02567 0.015625 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 0.890625 0.890625 0.890625 0.890625 Cysteine and methionine metabolism|Metabolic pathways 0.890625 K01740:metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] 0.890625 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1613503 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)FSLSQIVDAVSEK MGYG000001415_01540 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_01540 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 1376705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3388014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2174424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GAAEAYFGK MGYG000000098_00424 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides bouchesdurhonensis|m__MGYG000000098 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000098_00424 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1039254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3200144 0 0 0 0 0 3100441 0 0 2936533 2456064 0 0 0 0 0 0 0 0 0 3154837 0 565773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1237207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351765 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1561986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GAMLTIMNPDDKAGLEAALR MGYG000003074_00586;MGYG000000028_00944;MGYG000000404_01798;MGYG000002141_01824;MGYG000001777_01059;MGYG000001367_03001;MGYG000003486_02521;MGYG000001617_02046;MGYG000002528_02668;MGYG000001615_04300 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 0.4 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 0.6 etfB 1.0 - 1.0 - 0.8 ko:K03521 0.8 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.8 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003074_00586 0.1 - - - - 0.8 0.8 0.8 0.8 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.8 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675612 0 0 0 0 955053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GDFGYNAR MGYG000003763_00610;MGYG000000044_03505;MGYG000003351_04147;MGYG000003693_01240;MGYG000000196_04163;MGYG000003521_02097;MGYG000002171_01748;MGYG000001056_01919;MGYG000001659_02186;MGYG000003697_01689;MGYG000004899_00357;MGYG000003546_01342;MGYG000003353_01540;MGYG000004464_01712;MGYG000000029_01790;MGYG000001787_00205;MGYG000001433_02375;MGYG000001364_01313;MGYG000003251_00039;MGYG000000243_00634;MGYG000001763_00612;MGYG000001337_03744;MGYG000000215_01245;MGYG000000254_00174;MGYG000002051_00902;MGYG000001789_02329;MGYG000004495_01278;MGYG000002834_01380;MGYG000000355_02196;MGYG000002281_01780;MGYG000000013_01093;MGYG000003374_00724;MGYG000002478_00380;MGYG000003363_02977;MGYG000002218_01379;MGYG000003282_01136;MGYG000002293_01257;MGYG000000174_04760;MGYG000001925_02203;MGYG000001378_04618;MGYG000001306_00685;MGYG000001345_00379;MGYG000004763_01826;MGYG000002549_02837;MGYG000001770_01876;MGYG000002033_00862;MGYG000002438_00745;MGYG000002455_00111;MGYG000001489_00629;MGYG000000272_02397;MGYG000002133_00999;MGYG000002960_01776;MGYG000003252_04996;MGYG000000138_02067;MGYG000000117_00896;MGYG000004758_01391 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003763_00610 0.017857142857142856 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GFEIIK MGYG000001651_00562;MGYG000002549_01269;MGYG000000196_00779;MGYG000000098_01850 domain d__Bacteria 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 0.75 976|Bacteroidetes 0.75 H 0.75 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 0.75 pfp 0.75 - 1.0 2.7.1.11,2.7.1.90 0.75 ko:K00895,ko:K21071 0.75 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 0.75 - 1.0 R00756,R00764,R02073,R03236,R04779 0.75 RC00002,RC00017 0.75 ko00000,ko00001,ko01000 0.75 - 1.0 - 1.0 - 1.0 PFK 0.75 - 1.0 - 1.0 - 1.0 GT106 0.75 MGYG000001651_00562 0.25 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 0.75 0.75 0.75 0.75 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 0.75 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 52716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2486123 0 0 0 0 0 0 0 0 0 0 1272323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GFELLK MGYG000000196_00779 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 MGYG000000196_00779 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1664851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GFGIAMHTLDGGR MGYG000000080_01475;MGYG000002528_02667;MGYG000000204_00801;MGYG000000127_04022;MGYG000001793_01807;MGYG000002945_00737;MGYG000001615_04301;MGYG000000139_01931;MGYG000001564_00904;MGYG000000164_00686;MGYG000001315_01868;MGYG000001814_02502;MGYG000001617_02045;MGYG000000028_00943;MGYG000003486_02522 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.4 186801|Clostridia 1.0 C 0.6 acyl-CoA dehydrogenase 0.4666666666666667 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_01475 0.06666666666666667 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GGDDANTAFEK MGYG000000089_00652 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,3WGYK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000089_00652 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1868568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1819490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GGMTGTALTEEKEFR MGYG000004733_00567;MGYG000000002_00058;MGYG000000212_01327;MGYG000000133_00962;MGYG000000142_00060 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3XYPH@572511|Blautia 1.0 186801|Clostridia 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane 1.0 secA 1.0 - 1.0 - 1.0 ko:K03070 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 1.0 - 1.0 - 1.0 Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW 1.0 - 1.0 - 1.0 GT41 1.0 - 1.0 MGYG000004733_00567 0.2 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03070:secA; preprotein translocase subunit SecA [EC:7.4.2.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 722558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GGRDDVVDFVK MGYG000000164_01756 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,27JFG@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000164_01756 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 2219265 1339177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1198896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270779 0 0 0 0 0 0 0 0 0 0 0 0 276886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243869 0 0 0 0 0 0 0 0 546753 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GIIHFAASK MGYG000004797_00724;MGYG000004757_00891;MGYG000003693_02823;MGYG000001750_00316;MGYG000001364_01807;MGYG000002478_04317;MGYG000004464_00098;MGYG000000243_00999 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1087@1|root,COG1087@2|Bacteria,4NEM9@976|Bacteroidetes,2FMV2@200643|Bacteroidia,4AMM1@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family 0.875 galE 1.0 - 1.0 5.1.3.2 1.0 ko:K01784 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00361,M00362,M00632 1.0 R00291,R02984 1.0 RC00289 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_00724 0.125 UDP-glucose 4-epimerase. uridine diphospho-galactose-4-epimerase. Also acts on UDP-2-deoxyglucose. UDP-alpha-D-glucose = UDP-alpha-D-galactose. 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K01784:galE, GALE; UDP-glucose 4-epimerase [EC:5.1.3.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1214645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GKSYYFDTDGK MGYG000000255_01008 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01008 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1568002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GLSRPLIGMHFFNPADR MGYG000001300_00294 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00294 1.0 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GLVGSIEAADAMVK MGYG000000150_00816;MGYG000001311_03739;MGYG000001564_02266;MGYG000000179_01371;MGYG000000233_02830;MGYG000001171_01490;MGYG000001714_00561;MGYG000000198_01506;MGYG000001367_03226;MGYG000003589_02226;MGYG000002938_00022;MGYG000000150_00833 domain d__Bacteria 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 0.5833333333333334 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 0.6666666666666666 NPD7_940 0.6666666666666666 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00816 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 722652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1294065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GNADAALAAK MGYG000001255_00192 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_F|m__MGYG000001255 1.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3WG9R@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 aconitate hydratase 1.0 acnA 1.0 - 1.0 4.2.1.3 1.0 ko:K01681 1.0 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 1.0 M00009,M00010,M00012,M00173,M00740 1.0 R01324,R01325,R01900 1.0 RC00497,RC00498,RC00618 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aconitase,Aconitase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001255_00192 1.0 aconitate hydratase. citrate hydro-lyase. Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate.-!-The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate.-!-cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate.-!-Formerly EC 4.2.1.4. citrate = D-threo-isocitrate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Glyoxylate and dicarboxylate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K01681:ACO, acnA; aconitate hydratase [EC:4.2.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2190817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GNGAILITTK MGYG000000196_00769 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4AWE8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00769 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2356720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GQVYVLSKEEGGR MGYG000004526_00639;MGYG000001616_00520 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,2N71Q@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004526_00639 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GTDVMIAGK MGYG000003423_00948 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__W3P20-009|g__W3P20-009|s__W3P20-009 sp900766825|m__MGYG000003423 1.0 COG0499@1|root,COG0499@2|Bacteria,4NEKE@976|Bacteroidetes,2FPWZ@200643|Bacteroidia,3XJY8@558415|Marinilabiliaceae 1.0 976|Bacteroidetes 1.0 H 1.0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 1.0 ahcY 1.0 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 1.0 3.3.1.1 1.0 ko:K01251 1.0 ko00270,ko01100,map00270,map01100 1.0 M00035 1.0 R00192,R04936 1.0 RC00056,RC00069,RC01161,RC01243 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko04147 1.0 - 1.0 - 1.0 - 1.0 AdoHcyase,AdoHcyase_NAD,Flavokinase,NUDIX 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003423_00948 1.0 adenosylhomocysteinase. SAHase. The enzyme contains one tightly bound NAD(+) per subunit.-!-This appears to bring about a transient oxidation at C-3' of the 5'-deoxyadenosine residue, thus labilizing the thioether bond, cf. EC 5.5.1.4.-!-Formerly EC 3.3.1.1. H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways 1.0 K01251:AHCY, ahcY; adenosylhomocysteinase [EC:3.13.2.1] 1.0 none 1.0 0 1319986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1280457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 879821 0 0 0 +(Methyl)GVAGTIFVHK MGYG000000179_02177;MGYG000000198_04018;MGYG000000164_02351;MGYG000001311_02985 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia 0.5 186801|Clostridia 1.0 G 1.0 Dihydroxyacetone kinase 0.5 dhaK 1.0 - 1.0 2.7.1.121 1.0 ko:K05878 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak1,SDH_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02177 0.25 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways 1.0 K05878:dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] 1.0 none 1.0 1419431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)GVDSSVFETLR MGYG000003351_00939 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900765785|m__MGYG000003351 1.0 COG0015@1|root,COG0015@2|Bacteria,4NFY8@976|Bacteroidetes,2FMYF@200643|Bacteroidia,4AMJJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 purB 1.0 - 1.0 4.3.2.2 1.0 ko:K01756 1.0 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 1.0 M00048,M00049 1.0 R01083,R04559 1.0 RC00379,RC00444,RC00445 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADSL_C,ASL_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003351_00939 1.0 adenylosuccinate lyase. succino AMP-lyase. Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole. (1) N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate. (2) (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamide + fumarate. 1.0 1.0 1.0 1.0 Purine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01756:purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 483643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)IGTVGDAVSYIEANAK MGYG000002478_01408;MGYG000002560_00500;MGYG000004797_04291;MGYG000003282_01546 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0236@1|root,COG0236@2|Bacteria,4NS6C@976|Bacteroidetes,2FTWG@200643|Bacteroidia,4ARQA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Carrier of the growing fatty acid chain in fatty acid biosynthesis 1.0 acpP 1.0 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 1.0 - 1.0 ko:K02078 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001 1.0 - 1.0 - 1.0 - 1.0 PP-binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01408 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02078:acpP, acpM; acyl carrier protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 19601458 11436891 0 0 0 0 0 0 0 4956677 0 0 0 0 0 0 0 0 0 0 0 334014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31492160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6563968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)IQALADAAR MGYG000000150_02059;MGYG000000242_01807;MGYG000002602_00833;MGYG000000278_00929;MGYG000000967_00332;MGYG000000077_02594;MGYG000001714_01312;MGYG000001564_01915;MGYG000000262_00162;MGYG000004869_03336;MGYG000001526_00290;MGYG000004547_00257;MGYG000001507_06267 domain d__Bacteria 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,2206V@1506553|Lachnoclostridium 0.38461538461538464 186801|Clostridia 0.8461538461538461 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 0.8461538461538461 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_02059 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4759521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)IVGLYSAPAGSTVLIDR MGYG000000557_01986 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__|m__MGYG000000557 1.0 COG1982@1|root,COG1982@2|Bacteria,1MWK4@1224|Proteobacteria,2VIJQ@28216|Betaproteobacteria,4PRNS@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 E 1.0 Orn/Lys/Arg decarboxylase, N-terminal domain 1.0 adiA 1.0 - 1.0 4.1.1.18,4.1.1.19 1.0 ko:K01582,ko:K01584 1.0 ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110 1.0 M00133 1.0 R00462,R00566 1.0 RC00299 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 OKR_DC_1,OKR_DC_1_C,OKR_DC_1_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000557_01986 1.0 lysine decarboxylase. | arginine decarboxylase. L-lysine carboxy-lyase. | L-arginine carboxy-lyase. Also acts on 5'-hydroxy-L-lysine. H(+) + L-lysine = cadaverine + CO2. | H(+) + L-arginine = agmatine + CO2. 1.0 1.0 1.0 1.0 Lysine degradation|Arginine and proline metabolism|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01582:E4.1.1.18, ldcC, cadA; lysine decarboxylase [EC:4.1.1.18]|K01584:adiA; arginine decarboxylase [EC:4.1.1.19] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)KAEDLKELYVLPENDLK MGYG000000198_05929 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,21ZAM@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_05929 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 5239375 1476378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3607914 0 3624455 0 0 0 0 0 0 5605543 0 0 4807045 0 0 0 0 0 0 4730457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2718948 0 3092325 0 4969809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2176641 0 0 0 0 0 0 0 0 1858559 0 0 4856938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)KGDLYGVDLGGDVIPLPK MGYG000003166_00269 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539885|m__MGYG000003166 1.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGC7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 P 1.0 Belongs to the ABC transporter superfamily 1.0 - 1.0 - 1.0 - 1.0 ko:K10112 1.0 ko02010,map02010 1.0 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1 1.0 - 1.0 - 1.0 ABC_tran,TOBE,TOBE_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_00269 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10112:msmX, msmK, malK, sugC, ggtA, msiK; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)KYSPQEISAMILQK MGYG000003012_00270;MGYG000000690_01090;MGYG000002276_02250;MGYG000001551_00080;MGYG000004697_01220;MGYG000000175_03865;MGYG000001615_03019;MGYG000000200_01023;MGYG000000002_00433;MGYG000001714_02275;MGYG000000249_01105;MGYG000000181_00382;MGYG000004869_03374;MGYG000000171_01795;MGYG000002126_00706;MGYG000001689_04245;MGYG000000262_01374;MGYG000002772_01367;MGYG000001310_00050;MGYG000000038_00915;MGYG000001315_00535;MGYG000004733_01142;MGYG000000142_01918;MGYG000003427_02364;MGYG000004740_00081;MGYG000000077_00522;MGYG000000202_02200;MGYG000000251_02358;MGYG000002279_01669;MGYG000003335_02400;MGYG000000164_00503;MGYG000003165_00617;MGYG000000562_02511;MGYG000004879_00274;MGYG000004296_02335;MGYG000002974_00091;MGYG000003821_01669;MGYG000004547_01722;MGYG000000287_03181;MGYG000001374_00251;MGYG000001303_03339;MGYG000000133_02344;MGYG000004762_01166;MGYG000002234_00982 domain d__Bacteria 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia 0.5227272727272727 186801|Clostridia 0.9772727272727273 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 0.9772727272727273 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003012_00270 0.022727272727272728 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)LDNLVLR MGYG000002469_00977;MGYG000001292_01716 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0406@1|root,COG0406@2|Bacteria,2GK2I@201174|Actinobacteria,4CZH2@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Phosphoglycerate mutase family 1.0 - 1.0 - 1.0 5.4.2.12 1.0 ko:K15634 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 His_Phos_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002469_00977 0.5 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K15634:gpmB; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)LGNPSLTQVEEK MGYG000002057_00001 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Dysosmobacter|s__Dysosmobacter sp001916835|m__MGYG000002057 1.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,25E6I@186801|Clostridia,2N74S@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Methionine gamma-lyase 1.0 megL 1.0 - 1.0 2.5.1.48,4.4.1.11 1.0 ko:K01739,ko:K01761 1.0 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 1.0 M00017 1.0 R00654,R00999,R01288,R02508,R03217,R03260,R04770,R04944,R04945,R04946 1.0 RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02848,RC02866 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002057_00001 1.0 cystathionine gamma-synthase. | methionine gamma-lyase. O-succinyl-L-homoserine succinate-lyase (adding cysteine). | methionine lyase. Also reacts with H2S and methanethiol as replacing agents, producing homocysteine and methionine, respectively.-!-In the absence of thiol, can also catalyze beta,gamma-elimination to form 2-oxobutanoate, succinate and ammonia.-!-Formerly EC 4.2.99.9. | The enzyme cleaves a carbon-sulfur bond, releasing methanethiol and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form 2-oxobutanoate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-The enzyme is involved in L-methionine catabolism. L-cysteine + O-succinyl-L-homoserine = H(+) + L,L-cystathionine + succinate. | H2O + L-methionine = 2-oxobutanoate + methanethiol + NH4(+). 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Selenocompound metabolism|Sulfur metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K01739:metB; cystathionine gamma-synthase [EC:2.5.1.48]|K01761:E4.4.1.11; methionine-gamma-lyase [EC:4.4.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3187953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)LSSANSINIGR MGYG000001617_01152;MGYG000000255_01003;MGYG000003013_01480;MGYG000004087_00427 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,21ZGH@1506553|Lachnoclostridium 0.75 186801|Clostridia 1.0 E 1.0 Threonine synthase 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001617_01152 0.25 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 892291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502650 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)LSTTITGLEMFRK MGYG000003166_01350;MGYG000000022_02283;MGYG000002224_01123;MGYG000002040_01212;MGYG000002272_01482 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_01350 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125739 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)MMQPQIKPVDEHSAGDIIAR MGYG000002494_03452;MGYG000002477_02737 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3143@1|root,COG3143@2|Bacteria,1NIV6@1224|Proteobacteria,1RNG2@1236|Gammaproteobacteria,3XM8Y@561|Escherichia 0.5 1236|Gammaproteobacteria 1.0 J 0.5 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) 1.0 cheZ 1.0 GO:0001539,GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0032991,GO:0036211,GO:0040011,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071704,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0097588,GO:0098561,GO:0140096,GO:1901564 1.0 - 1.0 ko:K03414 1.0 ko02030,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheZ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03452 0.5 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis 1.0 K03414:cheZ; chemotaxis protein CheZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1677556 0 0 0 0 0 0 2258509 0 0 0 0 0 0 2185367 0 1954201 0 2801449 2499772 0 1737992 1650411 0 0 0 0 2027774 0 0 1641889 0 0 0 0 1330429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)MNKSDLISAMAAEAQMSK MGYG000003312_02172;MGYG000000013_02349 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia,4ARQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003312_02172 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 0 0 0 0 0 1102668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1550675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)NDGASIAEVTGR MGYG000002223_00691;MGYG000002619_01468;MGYG000002651_02042;MGYG000000022_01688;MGYG000002641_02245 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,3WHDM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 T 1.0 Psort location CytoplasmicMembrane, score 1.0 cstA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CstA,CstA_5TM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002223_00691 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 2661035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8873287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)NDGVVLVTTK MGYG000000236_04054 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AKMU@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_04054 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 923772 0 0 0 0 0 0 0 0 0 0 1034961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)NGATVSGPVPLPTKK MGYG000000251_01832 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter saccharivorans|m__MGYG000000251 1.0 COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,2N66W@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 KLT 1.0 Protein kinase domain 1.0 prkC 1.0 - 1.0 2.7.11.1 1.0 ko:K12132 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01001 1.0 - 1.0 - 1.0 - 1.0 PASTA,PBP1_TM,Pkinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_01832 1.0 non-specific serine/threonine protein kinase. threonine-specific protein kinase. This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.-!-Formerly EC 2.7.1.37 and EC 2.7.1.70. (1) ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]. (2) ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl- [protein]. 1.0 1.0 1.0 1.0 - 1.0 K12132:prkC, stkP; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1708104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)NGLPSLFDFEKK MGYG000003899_01005 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539945|m__MGYG000003899 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000003899_01005 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 1499073 0 0 0 0 0 0 0 0 1283104 0 0 0 0 0 0 0 0 1495891 0 0 0 0 0 0 1110585 0 0 0 0 1148011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)NLDYDLIITGR MGYG000000077_02468;MGYG000000080_01476;MGYG000001637_02230;MGYG000000087_01268;MGYG000001777_01059;MGYG000002067_00419;MGYG000002445_02276;MGYG000002528_02668;MGYG000000028_00944;MGYG000000271_02101;MGYG000000404_01798;MGYG000003694_00880;MGYG000000398_00614;MGYG000000255_01557;MGYG000002492_00660;MGYG000000154_01281;MGYG000000356_02130;MGYG000002517_00543;MGYG000004762_01002;MGYG000000262_02235;MGYG000000217_01341 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.5714285714285714 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.5714285714285714 etfB 1.0 - 0.9047619047619048 - 0.8571428571428571 ko:K03521 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.8571428571428571 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.047619047619047616 - - - - 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.8571428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 562191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 533296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)NLFKDEVR MGYG000003166_01352;MGYG000000251_01432;MGYG000002934_01864;MGYG000001255_01096;MGYG000002223_00095;MGYG000000389_01945;MGYG000002545_00612;MGYG000003899_01640;MGYG000002492_00550;MGYG000002641_00286;MGYG000002517_02553;MGYG000002274_01246;MGYG000000271_01306;MGYG000000133_02533;MGYG000000022_02285;MGYG000001300_00155;MGYG000002619_02218;MGYG000001319_01195;MGYG000002670_00532;MGYG000000398_02147;MGYG000000187_01380;MGYG000001637_01668;MGYG000002272_01480;MGYG000001814_03139;MGYG000000489_01853;MGYG000004548_02048;MGYG000003422_00594 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3WGXK@541000|Ruminococcaceae 0.4074074074074074 186801|Clostridia 0.9629629629629629 F 1.0 Catalyzes the synthesis of GMP from XMP 1.0 guaA 1.0 - 0.9629629629629629 6.3.5.2 0.9629629629629629 ko:K01951 0.9629629629629629 ko00230,ko00983,ko01100,map00230,map00983,map01100 1.0 M00050 1.0 R01230,R01231,R08244 1.0 RC00010,RC00204 1.0 ko00000,ko00001,ko00002,ko01000,ko01002 0.9629629629629629 - 1.0 - 1.0 - 0.9629629629629629 ATP_bind_3,GATase,GMP_synt_C,NAD_synthase,ThiI,tRNA_Me_trans 0.9629629629629629 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_01352 0.037037037037037035 GMP synthase (glutamine-hydrolyzing). GMP synthetase (glutamine-hydrolyzing). Involved in the de novo biosynthesis of guanosine nucleotides.-!-An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain.-!-The enzyme can catalyze the second reaction alone in the presence of ammonia.-!-Formerly EC 6.3.4.1. ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate. 0.9629629629629629 0.9629629629629629 0.9629629629629629 0.9629629629629629 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways 1.0 K01951:guaA, GMPS; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] 0.9629629629629629 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1163280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1202430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1046268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 741157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1798235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)NNLGELAYQAGK MGYG000004763_02569 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004763_02569 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 4957033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)NPVQVNEAAGFVVNR MGYG000000022_01323;MGYG000002040_01716 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01323 0.5 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1207030 0 0 0 0 703790 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)NVTADSIAK MGYG000002057_01748 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Dysosmobacter|s__Dysosmobacter sp001916835|m__MGYG000002057 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,2N6SP@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002057_01748 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 3391224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1057984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)NVVLLFQK MGYG000001567_01136 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__|m__MGYG000001567 1.0 COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,4CUPQ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline 1.0 argF 1.0 - 1.0 2.1.3.3 1.0 ko:K00611 1.0 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 1.0 M00029,M00844 1.0 R01398 1.0 RC00096 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001567_01136 1.0 ornithine carbamoyltransferase. OTCase. The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively. carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00611:OTC, argF, argI; ornithine carbamoyltransferase [EC:2.1.3.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1002873 0 2079990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 62986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)NYANQTLLR MGYG000003367_00149;MGYG000004763_01978;MGYG000002082_00368;MGYG000003493_01296;MGYG000000043_00075;MGYG000002218_00065;MGYG000003363_00419;MGYG000001306_00718;MGYG000003279_02442;MGYG000000355_00809;MGYG000000003_00510;MGYG000001783_00052;MGYG000000273_02673;MGYG000004479_00771;MGYG000001364_00648 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.6 976|Bacteroidetes 1.0 G 1.0 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.6 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003367_00149 0.06666666666666667 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1038124 832224 1348645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150682 0 0 +(Methyl)QLLAMTK MGYG000000243_02146 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,2FQ1C@200643|Bacteroidia,4AMBP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family 1.0 mtrC 1.0 - 1.0 - 1.0 ko:K03585 1.0 ko01501,ko01503,map01501,map01503 1.0 M00646,M00647,M00699,M00718 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 1.0 2.A.6.2,8.A.1.6 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02146 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|Cationic antimicrobial peptide (CAMP) resistance 1.0 K03585:acrA, mexA, adeI, smeD, mtrC, cmeA; membrane fusion protein, multidrug efflux system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)QSVSQYVASVAK MGYG000000179_02938;MGYG000000242_00796 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,21ZJJ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02938 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2485816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)SAFPGAIK MGYG000004797_01529 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AWE5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01529 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1570210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)SIAQQQNTQFK MGYG000000076_01275;MGYG000003694_00879;MGYG000000280_01471;MGYG000000153_01461;MGYG000000136_00900;MGYG000001637_02229;MGYG000000271_02102;MGYG000004271_00233;MGYG000000389_02149;MGYG000001186_01721;MGYG000002492_00659;MGYG000002670_01509;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.6923076923076923 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 0.6923076923076923 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000076_01275 0.07692307692307693 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 6179705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1057361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3293943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)SISIDPEVIKR MGYG000002455_04364 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002455_04364 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1155723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)SLEEGQAVSYDLTEGAR MGYG000002989_01533;MGYG000000287_00735;MGYG000000142_02892;MGYG000000031_02446;MGYG000001698_02841;MGYG000001689_05168;MGYG000004869_01115;MGYG000000263_01644;MGYG000000119_01719;MGYG000003147_00139;MGYG000004747_02624;MGYG000001602_00984;MGYG000000216_02459 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 Cold shock protein 1.0 - 1.0 - 1.0 - 1.0 ko:K03704 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 CSD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002989_01533 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03704:cspA; cold shock protein 1.0 none 1.0 0 465781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)SQQVTDAC(Carbamidomethyl)KK MGYG000004899_01569;MGYG000002323_01973;MGYG000002478_01945;MGYG000000243_02673;MGYG000001313_01946;MGYG000004464_00188;MGYG000003681_00341;MGYG000000098_02497;MGYG000001780_03233;MGYG000002506_00941;MGYG000000222_02644;MGYG000002455_02631 domain d__Bacteria 1.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,4NE85@976|Bacteroidetes,2FNPE@200643|Bacteroidia,4AKTC@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 0.8333333333333334 C 1.0 Catalyzes the reversible hydration of fumarate to (S)- malate 0.8333333333333334 fumB 0.8333333333333334 - 0.8333333333333334 4.2.1.2 1.0 ko:K01676 1.0 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00374 1.0 R01082 1.0 RC00443 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 0.8333333333333334 Fumerase,Fumerase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004899_01569 0.08333333333333333 fumarate hydratase. fumarase. - (S)-malate = fumarate + H2O. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01676:E4.2.1.2A, fumA, fumB; fumarate hydratase, class I [EC:4.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)SREFEPDAPNYTPR MGYG000002835_02584;MGYG000004735_01618;MGYG000000031_02755 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3XZ1G@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 8.87 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 IMP_cyclohyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002835_02584 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)SVDVMVK MGYG000000078_01647;MGYG000002528_01864;MGYG000000278_00938;MGYG000003215_00849;MGYG000004055_01475;MGYG000002417_02110;MGYG000003500_00156;MGYG000002559_01476;MGYG000001141_01291;MGYG000001564_01925;MGYG000003786_01019;MGYG000000204_02185;MGYG000001619_00808;MGYG000001793_01089;MGYG000002052_00761;MGYG000000028_01597;MGYG000004879_02709 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,21ZID@1506553|Lachnoclostridium 0.5294117647058824 186801|Clostridia 1.0 J 0.8823529411764706 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 0.6470588235294118 rpsD 0.6470588235294118 - 1.0 - 1.0 ko:K02986 0.6470588235294118 ko03010,map03010 0.8823529411764706 M00178,M00179 0.8823529411764706 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.8823529411764706 - 1.0 - 1.0 - 0.8823529411764706 Ribosomal_S4,S4 0.6470588235294118 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000078_01647 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.8823529411764706 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 0.6470588235294118 none 1.0 3609657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1383354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1764186 0 0 0 0 0 0 0 0 0 0 156719 0 +(Methyl)SVEELIEVVK MGYG000004733_01558 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase delta subunit 1.0 acsD 1.0 - 1.0 2.1.1.245 1.0 ko:K00194 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_01558 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00194:cdhD, acsD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] 1.0 none 1.0 491780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)SYYFDTDGK MGYG000000255_01008 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01008 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 11397768 8195866 0 0 6276071 0 0 0 0 0 0 7404045 0 0 0 0 8674442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12576693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2520831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2551628 0 0 0 0 0 0 0 0 0 0 0 2388006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)TAAILFSK MGYG000004797_02947;MGYG000002478_02940 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_02947 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379588 0 0 0 0 472782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 68852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)TSEVLIDYR MGYG000004642_00430 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG2998@1|root,COG2998@2|Bacteria,1UI9K@1239|Firmicutes,25EEI@186801|Clostridia,36S90@31979|Clostridiaceae 1.0 2|Bacteria 1.0 H 1.0 Copper amine oxidase N-terminal domain 1.0 - 1.0 - 1.0 - 1.0 ko:K05772 1.0 ko02010,map02010 1.0 M00186 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.6.2,3.A.1.6.4 1.0 - 1.0 - 1.0 CAP,Cu_amine_oxidN1,NHL,PBP_like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004642_00430 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K05772:tupA, vupA; tungstate transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2849268 0 0 0 0 1746716 0 0 1039361 2968550 0 1331791 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)TVEQAGMPMR MGYG000001733_00306 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550615|m__MGYG000001733 1.0 COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,247Q7@186801|Clostridia,25V46@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 1.0 - 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00175 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001733_00306 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00175:korB, oorB, oforB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VASIVGR MGYG000002534_00124 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_A|s__Citrobacter_A farmeri|m__MGYG000002534 1.0 COG0696@1|root,COG0696@2|Bacteria,1MUQ1@1224|Proteobacteria,1RMJE@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECSE_1348.ECSE_3895,iJN746.PP_5056 1.0 Metalloenzyme,Phosphodiest,iPGM_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002534_00124 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K15633:gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2863217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VASIYYQGLMR MGYG000001378_04234;MGYG000000029_00498;MGYG000000236_01493;MGYG000002281_03613;MGYG000000196_02323;MGYG000001461_03024;MGYG000001345_03404;MGYG000000013_01747;MGYG000003312_00912;MGYG000002549_04269;MGYG000000098_00597;MGYG000000054_02343 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_04234 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 938430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VAVVADDLAQESR MGYG000004642_00531;MGYG000004285_00367 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670 1.0 COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,36FZP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 2-hydroxyglutaryl-CoA dehydratase, D-component 1.0 - 1.0 - 1.0 1.3.7.8,4.2.1.54 1.0 ko:K04112,ko:K20627 1.0 ko00362,ko00640,ko00643,ko01100,ko01120,ko01220,map00362,map00640,map00643,map01100,map01120,map01220 1.0 M00541 1.0 R02451,R02963 1.0 RC00002,RC00818,RC01839 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HGD-D 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004642_00531 0.5 benzoyl-CoA reductase. | lactoyl-CoA dehydratase. - Inactive toward aromatic acids that are not CoA esters but will also catalyze the reaction: NH3 + acceptor + 2 ADP + 2 phosphate = hydroxylamine + reduced acceptor + 2 ATP + H2O.-!-In the presence of reduced acceptor, but in the absence of oxidizable substrate, the enzyme catalyzes the hydrolysis of ATP to ADP plus phosphate.-!-Formerly EC 1.3.99.15. | A bacterial enzyme that is involved in propanoate fermentation (also known as the acrylate pathway). 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized 2[4Fe-4S]- [ferredoxin] + 2 phosphate = 2 ATP + benzoyl-CoA + 2 H2O + reduced 2[4Fe- 4S]-[ferredoxin]. | (R)-lactoyl-CoA = acryloyl-CoA + H2O. 1.0 1.0 1.0 1.0 Benzoate degradation|Propanoate metabolism|Styrene degradation|Metabolic pathways|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04112:bcrC, badD; benzoyl-CoA reductase subunit C [EC:1.3.7.8]|K20627:lcdB; lactoyl-CoA dehydratase subunit beta [EC:4.2.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 621293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1612563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VDEGLDVVER MGYG000001787_02427;MGYG000000042_00775 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001787_02427 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32729701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VEAALEKGDVEGAK MGYG000004479_00625;MGYG000001306_01045;MGYG000000781_01742;MGYG000001835_01871;MGYG000001783_00207 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004479_00625 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2145075 1707510 0 3239464 0 0 0 0 1988674 1660459 0 0 2088458 0 0 0 0 0 601224 0 1201084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VEGDSVIVQR MGYG000000997_00555;MGYG000001315_01867;MGYG000004762_01002;MGYG000000262_02235 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.5 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.5 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_00555 0.25 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6619098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8498000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VEISNTSHPFYTGK MGYG000000696_00259;MGYG000002438_02631;MGYG000001489_00349;MGYG000004848_01257 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0254@1|root,COG0254@2|Bacteria,4NS7P@976|Bacteroidetes,2FTUG@200643|Bacteroidia,22YDW@171551|Porphyromonadaceae 0.75 976|Bacteroidetes 1.0 J 1.0 50S ribosomal protein L31 type B 1.0 rpmE2 1.0 - 1.0 - 1.0 ko:K02909 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L31 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000696_00259 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02909:RP-L31, rpmE; large subunit ribosomal protein L31 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2682612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VEYGEAAFYGPK MGYG000002675_01264;MGYG000003693_02322;MGYG000000105_00777;MGYG000000224_02651;MGYG000001313_02731;MGYG000002109_00674;MGYG000003539_00169;MGYG000004241_01257;MGYG000000053_01342;MGYG000002478_04502;MGYG000003681_01663;MGYG000004797_02455;MGYG000001789_02626;MGYG000000462_01070;MGYG000003554_00847;MGYG000004763_00464;MGYG000002171_01299;MGYG000001661_02959;MGYG000004464_01888;MGYG000003992_01259 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0441@1|root,COG0441@2|Bacteria,4NEFT@976|Bacteroidetes,2FMAU@200643|Bacteroidia,4AMPD@815|Bacteroidaceae 0.55 976|Bacteroidetes 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000002675_01264 0.05 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01868:TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 445782 0 0 0 0 888080 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VFATYTQEQVDK MGYG000000278_03205 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA3402|s__UBA3402 sp003478355|m__MGYG000000278 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,36DKD@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000278_03205 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1411174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VFSINGEIKPGVR MGYG000004893_00612 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A sp900555485|m__MGYG000004893 1.0 COG3055@1|root,COG3055@2|Bacteria,378BK@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 S 1.0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Kelch_1,Kelch_4,Kelch_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004893_00612 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1375413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VFVHHENR MGYG000001783_01513 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900551065|m__MGYG000001783 1.0 COG3408@1|root,COG3408@2|Bacteria,4NF09@976|Bacteroidetes,2FMEX@200643|Bacteroidia,4ANWK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 glycogen debranching enzyme, archaeal type 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GDE_C,GDE_N 1.0 - 1.0 GH133 1.0 GH133 1.0 GH133 1.0 MGYG000001783_01513 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 852464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1185696 0 0 0 0 2065168 0 0 0 0 1927694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 926407 0 0 0 0 854538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1031130 0 0 0 0 1542802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VGDDVPTVQNPEYFR MGYG000001783_01377;MGYG000000043_01665 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,2FM2Z@200643|Bacteroidia,4AN6Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate 1.0 purL 1.0 - 1.0 6.3.5.3 1.0 ko:K01952 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04463 1.0 RC00010,RC01160 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C,GATase_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001783_01377 0.5 phosphoribosylformylglycinamidine synthase. phosphoribosylformylglycinamidine synthetase. - ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D- ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D- ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01952:PFAS, purL; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1540251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VGGYGEAVASFK MGYG000003693_01537 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG2433@1|root,COG2433@2|Bacteria,4PKWF@976|Bacteroidetes,2G069@200643|Bacteroidia,4AKR0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Porin_O_P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_01537 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809301 0 0 0 0 1468833 0 0 0 0 854045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VGIGPGSIC(Carbamidomethyl)TTR MGYG000000271_00603;MGYG000001558_01970;MGYG000002036_00721;MGYG000004513_02444;MGYG000000213_01314;MGYG000000348_01357;MGYG000000433_01485;MGYG000004271_01872;MGYG000001431_00382;MGYG000000204_01913;MGYG000002164_00434;MGYG000004735_02781;MGYG000002802_01985;MGYG000000146_01483;MGYG000002992_01076;MGYG000001654_00568;MGYG000003279_02037;MGYG000004468_00808;MGYG000000164_00891;MGYG000000205_01225;MGYG000001489_02595;MGYG000000170_02064;MGYG000000142_02314;MGYG000003446_00567;MGYG000004848_01417;MGYG000002721_01246;MGYG000003984_01817;MGYG000004899_03971;MGYG000003164_01607;MGYG000001681_02186;MGYG000003825_01286;MGYG000000263_02824;MGYG000000362_00934;MGYG000000280_00135;MGYG000001237_00306;MGYG000001559_01603;MGYG000000354_00044;MGYG000002515_00630;MGYG000004495_02116;MGYG000000273_02631;MGYG000000262_01414;MGYG000001306_01130;MGYG000001623_01024;MGYG000000412_01379;MGYG000001571_02994;MGYG000004847_02037;MGYG000003470_00956;MGYG000003149_00433;MGYG000001732_00933;MGYG000004006_00824;MGYG000003783_01872;MGYG000001645_00506;MGYG000002080_00704;MGYG000000080_01161;MGYG000000048_02015;MGYG000004797_02827;MGYG000000013_03187;MGYG000001432_00165;MGYG000003142_02362;MGYG000003493_00600;MGYG000004738_00436;MGYG000000196_04055;MGYG000002293_02133;MGYG000001370_01971;MGYG000002534_03593;MGYG000002535_01039;MGYG000002438_02195;MGYG000003391_01338;MGYG000000133_00306;MGYG000004658_02026;MGYG000000138_02900;MGYG000003390_00955;MGYG000004667_03662;MGYG000000356_01714;MGYG000003697_01312;MGYG000002836_02134;MGYG000004642_00172;MGYG000003694_03060;MGYG000000198_00495;MGYG000001611_01647;MGYG000002506_02025;MGYG000001359_00988;MGYG000003782.1_00452;MGYG000002494_04050;MGYG000004285_01802;MGYG000001637_01052;MGYG000002713_01239;MGYG000002737_00135;MGYG000002937_01780;MGYG000000092_00381;MGYG000001485_02667;MGYG000003236_01758;MGYG000003282_00251;MGYG000001630_01208;MGYG000004087_02343;MGYG000002067_00750;MGYG000001643_01399;MGYG000004464_01403;MGYG000002685_00288;MGYG000002901_00218;MGYG000004704_01124;MGYG000002997_01145;MGYG000000087_02531;MGYG000000562_02421;MGYG000003858_02319;MGYG000003162_00158;MGYG000001407_01210;MGYG000003022_00656;MGYG000001367_02921;MGYG000004517_00100;MGYG000004879_00512;MGYG000003338_02530;MGYG000002881_00044;MGYG000001313_02959;MGYG000002492_02315;MGYG000000489_00932;MGYG000003486_02497;MGYG000003202_01530;MGYG000002834_01472;MGYG000004850_00007;MGYG000004250_01264;MGYG000001327_01268;MGYG000000233_01272;MGYG000001193_00608;MGYG000003922_01814;MGYG000004727_00678;MGYG000001315_00701;MGYG000001781_01698;MGYG000000074_01340;MGYG000000187_01407;MGYG000002670_00089;MGYG000000437_01226;MGYG000002574_00994;MGYG000000243_00691;MGYG000004869_03402;MGYG000003549_00730;MGYG000004884_01768;MGYG000000989_02246;MGYG000001314_02149;MGYG000004785_01919;MGYG000000735_00745;MGYG000003868_00445;MGYG000000002_02500;MGYG000004828_01108;MGYG000002985_01150;MGYG000002960_01699;MGYG000004471_01025;MGYG000000374_01230;MGYG000003693_00994;MGYG000001056_01201;MGYG000000171_02641;MGYG000001423_03191;MGYG000000701_01634;MGYG000000003_02085;MGYG000003662_00787;MGYG000001701_00556;MGYG000002517_01047;MGYG000001346_00627;MGYG000000212_00040;MGYG000002485_02170;MGYG000001319_00739;MGYG000004851_00152;MGYG000000136_01100;MGYG000002966_01598;MGYG000002469_01587;MGYG000002895_00318;MGYG000003365.1_02647;MGYG000000089_02238;MGYG000000347_01341;MGYG000000215_00958;MGYG000001186_00833;MGYG000003352_01125;MGYG000000127_02910;MGYG000000206_01855;MGYG000004769_00915;MGYG000002963_04223;MGYG000001220_00502;MGYG000004740_01385;MGYG000001685_01145;MGYG000002905_02028;MGYG000002247_00883;MGYG000001412_04889;MGYG000001338_00214;MGYG000000301_00957;MGYG000001477_00304;MGYG000001748_02097;MGYG000000252_03031;MGYG000002478_00464;MGYG000003412_00366;MGYG000000098_03787;MGYG000002279_00396;MGYG000000077_00487;MGYG000000251_01328;MGYG000002298_01715;MGYG000003313_01965;MGYG000002835_00811;MGYG000003116_00649;MGYG000001219_01350;MGYG000003366_01162;MGYG000001787_00508;MGYG000003695_02134;MGYG000001395_02742;MGYG000001507_06410;MGYG000004893_01198 life d__Bacteria 0.9951 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia 0.08823529411764706 186801|Clostridia 0.5294117647058824 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 0.9901960784313726 guaB 1.0 - 0.8872549019607843 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 0.9362745098039216 CBS,IMPDH,NMO 0.6176470588235294 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00603 0.004901960784313725 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1242659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 964845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VGNTLSESGTVSR MGYG000000196_00016;MGYG000004757_01252;MGYG000002281_00884;MGYG000000044_00029;MGYG000002478_00412;MGYG000003539_00592;MGYG000000243_00646;MGYG000002033_02736;MGYG000002560_02783;MGYG000000215_00870;MGYG000002549_03470;MGYG000004474_01037;MGYG000002171_01765;MGYG000004797_03414;MGYG000001378_02628;MGYG000003312_02930 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1208@1|root,COG1208@2|Bacteria,4PKJR@976|Bacteroidetes,2G07F@200643|Bacteroidia,4AKG8@815|Bacteroidaceae 0.4375 976|Bacteroidetes 1.0 JM 0.875 COG NOG09722 non supervised orthologous group 0.875 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NTP_transf_3,NTP_transferase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00016 0.0625 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 887284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VIC(Carbamidomethyl)ENPK MGYG000003977_00980;MGYG000002926_00512;MGYG000004718_00086;MGYG000003160_00099;MGYG000001623_00884;MGYG000001464_01348;MGYG000004727_00030;MGYG000000365_01086;MGYG000003219_00818;MGYG000001500_00907;MGYG000003577_01703;MGYG000004810_00893;MGYG000001654_01669;MGYG000004854_01553;MGYG000000071_01854;MGYG000003581_01723;MGYG000004769_00461;MGYG000001460_03688;MGYG000004863_01347;MGYG000000369_01203;MGYG000004893_02156;MGYG000002079_00954;MGYG000001739_00922;MGYG000002139_01167;MGYG000004482_01012;MGYG000002993_00638;MGYG000004715_01204;MGYG000001601_01043;MGYG000003453_00403;MGYG000000405_00856;MGYG000002791_00834;MGYG000001646_00003;MGYG000004729_00728;MGYG000001470_03696;MGYG000004642_00876;MGYG000001746_00300;MGYG000000173_00321;MGYG000001563_00766;MGYG000004453_01158;MGYG000002715_01097;MGYG000000129_01145;MGYG000002702_01376;MGYG000000773_00999;MGYG000002707_00988;MGYG000001635_01410;MGYG000000258_00306;MGYG000001508_00059;MGYG000000435_00508;MGYG000003468_00750;MGYG000004249_00005;MGYG000002994_01290;MGYG000002964_01092;MGYG000000392_01436;MGYG000001405_04496;MGYG000000316_00896;MGYG000001732_00086;MGYG000001712_00145;MGYG000003484_01829;MGYG000003819_01183;MGYG000002716_01471;MGYG000004306_00025;MGYG000001756_01043;MGYG000004894_00054;MGYG000004809_00843;MGYG000000408_01127;MGYG000001488_02393;MGYG000002685_01383;MGYG000002485_02435;MGYG000000367_00545;MGYG000000477_01598;MGYG000003116_00454;MGYG000004784_00611;MGYG000000036_00601;MGYG000002057_00258;MGYG000001191_00894;MGYG000001626_01874;MGYG000002959_00707;MGYG000003465_00819;MGYG000004804_01241;MGYG000001702_03646;MGYG000001647_01148;MGYG000001474_01367;MGYG000004760_01483;MGYG000001326_01426;MGYG000001424_01384;MGYG000001913_00789;MGYG000002251_00158;MGYG000004517_01000;MGYG000001729_00295;MGYG000000182_00560;MGYG000001356_01792;MGYG000001238_00461;MGYG000000423_01045;MGYG000003538_00588;MGYG000002795_00391;MGYG000002848_00835;MGYG000003858_01271;MGYG000001577_00625;MGYG000001400_03640;MGYG000000493_00066;MGYG000000421_00578;MGYG000001697_01855;MGYG000001514_00066;MGYG000003871_00382;MGYG000001225_00112;MGYG000001553_00956;MGYG000000395_00100;MGYG000000919_01842;MGYG000002084_00612;MGYG000000377_01239;MGYG000002753_00096;MGYG000000374_00158;MGYG000000130_00521;MGYG000004700_01644;MGYG000000234_02029;MGYG000004565_00386;MGYG000001618_01418;MGYG000000099_02376;MGYG000000989_00131;MGYG000002659_00433;MGYG000004276_01064;MGYG000000385_00638;MGYG000002235_00892;MGYG000002105_00216;MGYG000004216_00457;MGYG000000073_01954;MGYG000004471_01172;MGYG000004628_02064;MGYG000004613_01552;MGYG000003510_00355;MGYG000001762_00997;MGYG000001507_06276;MGYG000000953_00554;MGYG000003961_00928;MGYG000003428_01084;MGYG000000910_01044;MGYG000000463_00767;MGYG000002953_00616;MGYG000001754_01550;MGYG000000177_02184;MGYG000001502_00387;MGYG000000121_02218;MGYG000004845_01930;MGYG000002042_01077;MGYG000000383_00908;MGYG000002720_00257;MGYG000002159_00236;MGYG000002903_00732;MGYG000000157_01118;MGYG000002067_01291;MGYG000002938_02179;MGYG000003307_01071;MGYG000002854_00085;MGYG000004502_01050;MGYG000000134_01732;MGYG000001477_00042;MGYG000002727_01961;MGYG000004526_00986;MGYG000002156_01375;MGYG000000413_00087;MGYG000004600_01297;MGYG000003153_00563;MGYG000000334_01933;MGYG000002315_01067;MGYG000004828_01829;MGYG000002026_01331;MGYG000004196_00613;MGYG000001365_00981;MGYG000000375_00837;MGYG000002857_00955;MGYG000002934_00498;MGYG000004252_00086 domain d__Bacteria 1.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,269B1@186813|unclassified Clostridiales 0.29651162790697677 186801|Clostridia 0.7848837209302325 J 0.9127906976744186 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex 0.5348837209302325 infA 0.5348837209302325 - 0.9941860465116279 - 1.0 ko:K02518 0.5348837209302325 - 0.6686046511627907 - 0.6686046511627907 - 1.0 - 1.0 ko00000,ko03012 0.5348837209302325 - 1.0 - 1.0 - 1.0 eIF-1a 0.5348837209302325 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003977_00980 0.005813953488372093 - - - - 1.0 1.0 1.0 1.0 - 0.6686046511627907 K02518:infA; translation initiation factor IF-1 0.5348837209302325 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6137540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VILPDPVFNDQK MGYG000000029_02786;MGYG000000236_01790;MGYG000002549_02928;MGYG000002293_00508;MGYG000001306_02657;MGYG000003697_01471;MGYG000000196_03986;MGYG000002281_02278;MGYG000002455_03896;MGYG000001337_03892;MGYG000002834_00437;MGYG000000243_01974;MGYG000002603_01770;MGYG000003312_02994;MGYG000000013_02239;MGYG000001787_02681;MGYG000000098_02005 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 0.8235294117647058 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000029_02786 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032740 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VITSFAGLR MGYG000002298_00538;MGYG000000038_01495;MGYG000000280_01802;MGYG000000404_00180;MGYG000001619_01503;MGYG000002312_03079;MGYG000000171_00187;MGYG000000255_01681;MGYG000000164_01752;MGYG000000271_03444;MGYG000001683_00852;MGYG000000301_00532;MGYG000002517_00473;MGYG000001311_02981;MGYG000000489_00238;MGYG000000154_01590;MGYG000000142_00484;MGYG000000153_02080;MGYG000000076_01007;MGYG000004087_02481;MGYG000002946_03411;MGYG000000245_01076;MGYG000000031_00359;MGYG000000205_00110;MGYG000002276_00835;MGYG000003074_00570;MGYG000000127_02775;MGYG000000179_02173;MGYG000002279_02522;MGYG000001315_01114;MGYG000004271_01228;MGYG000000212_00378;MGYG000000198_04022 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 0.30303030303030304 186801|Clostridia 1.0 S 0.6060606060606061 FAD dependent oxidoreductase 0.5151515151515151 - 0.9090909090909091 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_00538 0.030303030303030304 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 1174189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VKEVADAAR MGYG000001306_02676;MGYG000002281_02259;MGYG000000236_01771;MGYG000000013_02220;MGYG000002935_01255;MGYG000000196_04005;MGYG000004763_00942;MGYG000004748_03258;MGYG000001461_00420;MGYG000001378_05011;MGYG000002470_01214;MGYG000001337_03873;MGYG000002561_02191;MGYG000001313_00058;MGYG000000054_03874;MGYG000000442_02026;MGYG000000273_00390;MGYG000003693_00209;MGYG000002549_02909;MGYG000004479_01416;MGYG000001345_04715;MGYG000000029_02805;MGYG000000781_00864;MGYG000000042_01075;MGYG000004185_01147;MGYG000001925_01448;MGYG000000105_02020;MGYG000002933_02445;MGYG000003681_02067 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia,4AQZ3@815|Bacteroidaceae 0.9655172413793104 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_02676 0.034482758620689655 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1950474 0 0 0 0 0 0 0 0 0 0 0 0 0 1564310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VKGEPLTDFIGTTR MGYG000000196_02501;MGYG000002549_04620 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,2FNZ4@200643|Bacteroidia,4ANT4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the LDH MDH superfamily 1.0 mdh 1.0 - 1.0 1.1.1.37 1.0 ko:K00024 1.0 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 1.0 R00342,R07136 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ldh_1_C,Ldh_1_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_02501 0.5 malate dehydrogenase. malic dehydrogenase. Also oxidizes some other 2-hydroxydicarboxylic acids. (S)-malate + NAD(+) = H(+) + NADH + oxaloacetate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Cysteine and methionine metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00024:mdh; malate dehydrogenase [EC:1.1.1.37] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 719009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 197553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VLAEFAK MGYG000000233_00505;MGYG000000205_00362 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,21ZWI@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_00505 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02864:RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1166509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VLIMPGDNSSVPTMR MGYG000002720_00601 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG1879@1|root,COG1879@2|Bacteria,1UE0M@1239|Firmicutes,24C7Y@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system, periplasmic 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_00601 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1960455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VLKLETFR MGYG000001599_02035;MGYG000000224_00262;MGYG000003681_00233;MGYG000001661_00812 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG3717@1|root,COG3717@2|Bacteria,4NDUV@976|Bacteroidetes,2FMP5@200643|Bacteroidia,4AM3B@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate 1.0 kduI 1.0 - 1.0 5.3.1.17 1.0 ko:K01815 1.0 ko00040,map00040 1.0 - 1.0 R04383 1.0 RC00541 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 KduI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001599_02035 0.25 5-dehydro-4-deoxy-D-glucuronate isomerase. 5-keto-4-deoxyuronate isomerase. The enzyme is involved in the degradation of polygalacturonate, a later stage in the degradation of pectin by many microorganisms. 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions 1.0 K01815:kduI; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [EC:5.3.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VLPGIAAIR MGYG000001835_00603 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp000432735|m__MGYG000001835 1.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NIEK@976|Bacteroidetes,2FMAP@200643|Bacteroidia,4AKI4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 Psort location CytoplasmicMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001835_00603 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1071096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VLPGVAAIKGE MGYG000000243_00781;MGYG000003420_00378;MGYG000004703_01936;MGYG000001447_00495;MGYG000002478_02340 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 0.6 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 0.6 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00781 0.2 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 3704927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4267523 0 0 0 0 0 0 0 0 3276040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3771420 5841969 3650338 0 0 0 0 0 3263475 9524499 0 0 8552934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VLVATEKPFAK MGYG000003511_00832;MGYG000000029_02971;MGYG000003312_01933;MGYG000000013_04188;MGYG000001306_01782;MGYG000001415_00202;MGYG000001750_00741;MGYG000000196_03462;MGYG000001787_00809;MGYG000003693_03256;MGYG000002549_01443;MGYG000001337_02575;MGYG000001835_00780 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,4AKZ7@815|Bacteroidaceae 0.46153846153846156 976|Bacteroidetes 1.0 C 0.46153846153846156 Conserved protein 0.46153846153846156 - 0.6153846153846154 - 1.0 1.1.1.399,1.1.1.95 0.5384615384615384 ko:K00058 0.5384615384615384 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 0.5384615384615384 M00020 0.5384615384615384 R01513 0.5384615384615384 RC00031 0.5384615384615384 ko00000,ko00001,ko00002,ko01000,ko04147 0.5384615384615384 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 0.5384615384615384 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003511_00832 0.07692307692307693 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 0.5384615384615384 0.5384615384615384 0.5384615384615384 0.5384615384615384 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.5384615384615384 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 0.5384615384615384 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 923989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VNIEFDMPSR MGYG000002478_01480;MGYG000004479_01900;MGYG000000243_01831;MGYG000001787_00130 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1217@1|root,COG1217@2|Bacteria,4NDVM@976|Bacteroidetes,2FMNU@200643|Bacteroidia,4AMJB@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 GTP-binding protein TypA 1.0 typA 1.0 - 1.0 - 1.0 ko:K06207 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01480 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06207:typA, bipA; GTP-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VQEFLLNFGK MGYG000004797_02292;MGYG000002478_02024 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FM0V@200643|Bacteroidia,4ANJE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Xaa-His dipeptidase 1.0 pepD_2 1.0 - 1.0 - 1.0 ko:K01270 1.0 ko00480,ko01100,map00480,map01100 1.0 - 1.0 R00899,R04951 1.0 RC00096,RC00141 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_02292 0.5 - - - - 1.0 1.0 1.0 1.0 Glutathione metabolism|Metabolic pathways 1.0 K01270:pepD; dipeptidase D [EC:3.4.13.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VQFNNAIGPYK MGYG000003693_00515;MGYG000000415_01340;MGYG000001306_03642;MGYG000004464_00132;MGYG000000054_03508;MGYG000002561_00570;MGYG000000245_02477;MGYG000000348_00264;MGYG000002549_04345;MGYG000002218_02291;MGYG000003279_00861;MGYG000003681_00059;MGYG000000222_00649;MGYG000001345_03440;MGYG000000781_00162;MGYG000004879_02390;MGYG000003460_01711;MGYG000002609_02276;MGYG000002721_00727;MGYG000001346_00943;MGYG000002438_00729;MGYG000004797_04374;MGYG000000187_02311;MGYG000000356_00361;MGYG000000003_02629;MGYG000001789_02928;MGYG000002131_02188;MGYG000001666_02162;MGYG000002033_03142;MGYG000002205_00179;MGYG000003367_00479;MGYG000002470_04167;MGYG000002905_01332;MGYG000004757_01061;MGYG000004658_00724;MGYG000004763_01778;MGYG000000354_00366;MGYG000002455_00066;MGYG000002654_00571;MGYG000000243_02155;MGYG000001370_01143;MGYG000004380_02235;MGYG000000138_02030;MGYG000001643_02377;MGYG000002934_01476;MGYG000002517_02750;MGYG000001797_03050;MGYG000001637_01313;MGYG000000489_02253;MGYG000001489_00505;MGYG000000562_02592;MGYG000000196_02411;MGYG000003425_04268;MGYG000002258_01173;MGYG000000076_02271;MGYG000000355_01573;MGYG000002670_01100;MGYG000003133_03072;MGYG000001835_02316;MGYG000000273_02029;MGYG000000236_00923;MGYG000000044_02194;MGYG000002478_00277;MGYG000000174_04135;MGYG000000271_00907;MGYG000004468_00548 domain d__Bacteria 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AMNJ@815|Bacteroidaceae 0.4393939393939394 976|Bacteroidetes 0.696969696969697 C 0.45454545454545453 Belongs to the Glu Leu Phe Val dehydrogenases family 0.7272727272727273 gdh 0.7121212121212122 GO:0005575,GO:0005623,GO:0009986,GO:0044464 0.696969696969697 1.4.1.4 0.7272727272727273 ko:K00262 0.7272727272727273 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 0.7272727272727273 - 0.8787878787878788 R00248 0.7272727272727273 RC00006,RC02799 0.8484848484848485 ko00000,ko00001,ko01000 0.7272727272727273 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.8484848484848485 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_00515 0.015151515151515152 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.7272727272727273 0.7272727272727273 0.7272727272727273 0.7272727272727273 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 0.7272727272727273 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.7272727272727273 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507911 0 1448158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VTAEKNPADLK MGYG000001789_00244;MGYG000004479_00217;MGYG000000445_00706;MGYG000001783_01519;MGYG000002933_02039 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 C 0.8 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001789_00244 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5698020 0 0 0 4095051 0 0 0 0 0 0 6336316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2616693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VTIQNLEVVR MGYG000002835_00976;MGYG000000280_01267 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,21Z6A@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit 1.0 rplC 1.0 - 1.0 - 1.0 ko:K02906 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002835_00976 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02906:RP-L3, MRPL3, rplC; large subunit ribosomal protein L3 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 863401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VTYTEPGIKGDTATNTLKPATVESGATVR MGYG000000029_03015;MGYG000000098_03555 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0231@1|root,COG0231@2|Bacteria,4NDXA@976|Bacteroidetes,2FP84@200643|Bacteroidia,4AMEV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000029_03015 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02356:efp; elongation factor P 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1819527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VVC(Carbamidomethyl)EVVSGLVK MGYG000003681_00823 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0261@1|root,COG0261@2|Bacteria,4NSHE@976|Bacteroidetes,2FTJ4@200643|Bacteroidia,4AR0D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein binds to 23S rRNA in the presence of protein L20 1.0 rplU 1.0 GO:0003674,GO:0003735,GO:0005198 1.0 - 1.0 ko:K02888 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 DUF4332,HHH_5,Rho_N,Ribosomal_L21p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_00823 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02888:RP-L21, MRPL21, rplU; large subunit ribosomal protein L21 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1846025 0 0 2455068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VVDLIAPYAK MGYG000002777_01079;MGYG000004158_00761;MGYG000000411_00371 genus d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister 1.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4H2IA@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 - 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 MGYG000002777_01079 0.3333333333333333 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02112:ATPF1B, atpD; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1082967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VVFTAEDAK MGYG000004726_03204;MGYG000001502_03051 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,268N0@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000004726_03204 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1488154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 865023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VVGLQTEAPLKR MGYG000002506_00229 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1RM96@1236|Gammaproteobacteria,3XMX2@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 formate C-acetyltransferase activity 1.0 pflB 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECH74115_1262.ECH74115_1064,iECIAI39_1322.ECIAI39_2245,iECSP_1301.ECSP_1007,iECs_1301.ECs0986,iEcSMS35_1347.EcSMS35_2218,iG2583_1286.G2583_1138,iSDY_1059.SDY_2358,iZ_1308.Z1248 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00229 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 6097165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5850705 0 0 0 0 0 0 0 0 0 6369675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VVMIEDVTTSGK MGYG000002304_01630;MGYG000001379_01167;MGYG000002298_01629;MGYG000001314_03025;MGYG000002670_00027;MGYG000000141_00942;MGYG000001456.1_02603;MGYG000000119_01768;MGYG000000245_03142;MGYG000000200_01565;MGYG000000325_00864;MGYG000002517_00833;MGYG000000389_01227;MGYG000002596_02168;MGYG000000213_01465;MGYG000000133_02579;MGYG000000212_01799;MGYG000000252_02246;MGYG000001637_02321;MGYG000000489_01061;MGYG000004740_01192;MGYG000000204_00607;MGYG000001338_00074;MGYG000004719_01798;MGYG000000271_01398;MGYG000001528_01833;MGYG000004610_00048;MGYG000000184_02212;MGYG000001714_02809;MGYG000004747_02159;MGYG000002492_02249;MGYG000001602_00995;MGYG000001711_01559 domain d__Bacteria 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 0.5151515151515151 186801|Clostridia 0.9393939393939394 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 0.9393939393939394 ko:K00762 0.9393939393939394 ko00240,ko01100,map00240,map01100 0.9393939393939394 M00051 0.9393939393939394 R01870 0.9393939393939394 RC00611 0.9393939393939394 ko00000,ko00001,ko00002,ko01000 0.9393939393939394 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002304_01630 0.030303030303030304 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 0.9393939393939394 0.9393939393939394 0.9393939393939394 0.9393939393939394 Pyrimidine metabolism|Metabolic pathways 0.9393939393939394 K00762:pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] 0.9393939393939394 none 1.0 1423685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1087844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1971194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350163 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VVSWYDNEFGYSNR MGYG000001508_01079 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Bacillales_D|f__Halobacillaceae|g__Thalassobacillus|s__Thalassobacillus devorans|m__MGYG000001508 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli 1.0 91061|Bacilli 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gapA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001508_01079 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1408662 0 0 0 0 1456495 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VVTFLGR MGYG000003645_00336;MGYG000004464_00930;MGYG000001666_01195;MGYG000001780_02982;MGYG000001661_02656;MGYG000002171_02171;MGYG000002905_01300;MGYG000003202_00412;MGYG000000236_02485;MGYG000001378_02334;MGYG000003434_00296;MGYG000000215_01371;MGYG000002033_02334;MGYG000001337_01496;MGYG000002560_03190;MGYG000002455_04306;MGYG000000243_01312;MGYG000001806_01086;MGYG000004823_02033;MGYG000004797_02601;MGYG000004757_00359;MGYG000002478_03183;MGYG000000117_02886;MGYG000000196_00507 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0438@1|root,COG0438@2|Bacteria,4NEWR@976|Bacteroidetes,2FMW0@200643|Bacteroidia,4AKN5@815|Bacteroidaceae 0.5833333333333334 976|Bacteroidetes 1.0 M 0.9583333333333334 Glycosyltransferase, group 1 family protein 0.6666666666666666 gmhA 0.9583333333333334 - 1.0 2.4.1.346 0.9583333333333334 ko:K13668 0.9583333333333334 - 1.0 - 1.0 R11703,R11704 0.9583333333333334 - 1.0 ko00000,ko01000,ko01003 0.9583333333333334 - 1.0 GT4 0.9583333333333334 - 1.0 Glyco_trans_4_4,Glyco_transf_4,Glyco_transf_5,Glycos_transf_1,SIS_2 0.9583333333333334 - 1.0 GT4 1.0 GT4 1.0 GT4 1.0 MGYG000003645_00336 0.041666666666666664 phosphatidyl-myo-inositol dimannoside synthase. mannosyltransferase. The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs). (1) a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D- myo-inositol] + GDP-alpha-D-mannose = a 2,6-O-bis(alpha-D- mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+). (2) a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl- (1<->6)-D-myo-inositol] + GDP-alpha-D-mannose = 2-O-(alpha-D-mannosyl)-6- O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+). 0.9583333333333334 0.9583333333333334 0.9583333333333334 0.9583333333333334 - 1.0 K13668:pimB; phosphatidyl-myo-inositol dimannoside synthase [EC:2.4.1.346] 0.9583333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642026 0 0 0 0 0 0 0 998123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VVTLGEIMLR MGYG000004748_01870;MGYG000002281_02000;MGYG000001433_00077;MGYG000000013_04444;MGYG000001345_02616;MGYG000000196_03698;MGYG000003351_04347;MGYG000003493_01858;MGYG000002786_00778;MGYG000002291_01855;MGYG000002549_02252;MGYG000000054_04213;MGYG000002478_03488;MGYG000001378_01448;MGYG000004797_00251;MGYG000001806_00682;MGYG000003535_00588 domain d__Bacteria 1.0 COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,2FMMW@200643|Bacteroidia 0.7647058823529411 976|Bacteroidetes 1.0 G 1.0 glucuronate isomerase 0.7647058823529411 uxaC 0.7647058823529411 - 1.0 5.3.1.12 0.7647058823529411 ko:K01812 0.7647058823529411 ko00040,ko01100,map00040,map01100 0.7647058823529411 M00061,M00631 0.7647058823529411 R01482,R01983 0.7647058823529411 RC00376 0.7647058823529411 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 UxaC 0.7647058823529411 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004748_01870 0.058823529411764705 glucuronate isomerase. uronic isomerase. Also converts D-galacturonate to D-tagaturonate. D-glucuronate = D-fructuronate. 0.7647058823529411 0.7647058823529411 0.7647058823529411 0.7647058823529411 Pentose and glucuronate interconversions|Metabolic pathways 0.7647058823529411 K01812:uxaC; glucuronate isomerase [EC:5.3.1.12] 0.7647058823529411 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 657681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)VYTVTGTWNPDKPR MGYG000000224_01902 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp003545565|m__MGYG000000224 1.0 COG0584@1|root,COG0584@2|Bacteria,4NHVM@976|Bacteroidetes,2FNEP@200643|Bacteroidia,4AP34@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Glycerophosphoryl diester phosphodiesterase family 1.0 glpQ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GDPD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000224_01902 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5893141 0 0 0 0 0 0 0 0 0 0 0 3264605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl)WKDVNGDGVIDNYDMVK MGYG000002549_01340;MGYG000000236_04054 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AKMU@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_01340 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2553555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl_2H(2))ENADIYASLPEGVAR MGYG000000236_04310 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 MGYG000000236_04310 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 664223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl_2H(2))IEAGIIHVGDEVEILGLGEDKK MGYG000001789_00154;MGYG000001780_03476;MGYG000002455_03884 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001789_00154 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl_2H(2))NMYNGTSGTELMGK MGYG000001346_03050 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_03050 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 916899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1474523 0 +(Methyl_2H(2))SFATGIAGFSHVVDSLSAIK MGYG000000249_01153;MGYG000000212_03425;MGYG000001338_02009;MGYG000000146_00290;MGYG000000201_01290;MGYG000000142_01268;MGYG000000184_00650;MGYG000000133_01279 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3XZ2A@572511|Blautia 0.75 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 0.75 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_01153 0.125 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 136463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112413 0 5839545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2385888 0 0 0 0 0 0 0 0 0 0 8486436 0 2487768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4831943 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl_2H(2))SGETEDATIADIAVATNSGQIK MGYG000000174_03490;MGYG000000170_00013;MGYG000001780_02258;MGYG000001551_03232;MGYG000001306_00798;MGYG000004823_02623;MGYG000002438_02238;MGYG000002478_00851;MGYG000001461_01176;MGYG000001372_00511;MGYG000000105_02944;MGYG000000781_02456;MGYG000003363_02712;MGYG000003351_05187;MGYG000002033_02968;MGYG000003701_04731;MGYG000002478_03016;MGYG000000243_01149;MGYG000003363_01340;MGYG000000138_00292;MGYG000001787_01497;MGYG000003367_02246;MGYG000000355_00667;MGYG000002438_01170;MGYG000003362_00885;MGYG000002717_02775;MGYG000001346_02829;MGYG000001661_02794;MGYG000003312_00286;MGYG000001552_02061;MGYG000002455_01185;MGYG000002549_00850;MGYG000000196_01187;MGYG000003693_00001;MGYG000002455_05125;MGYG000002540_01420;MGYG000001655_00022;MGYG000000273_02920;MGYG000001364_02911;MGYG000001433_00549;MGYG000000013_00888 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 0.6585365853658537 976|Bacteroidetes 1.0 G 0.975609756097561 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 0.975609756097561 eno 0.975609756097561 - 1.0 4.2.1.11 0.975609756097561 ko:K01689 0.975609756097561 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 0.975609756097561 M00001,M00002,M00003,M00346,M00394 0.975609756097561 R00658 0.975609756097561 RC00349 0.975609756097561 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 0.975609756097561 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 0.975609756097561 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000000174_03490 0.024390243902439025 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 0.975609756097561 0.975609756097561 0.975609756097561 0.975609756097561 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 0.975609756097561 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 0.975609756097561 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl_2H(2))VAGNSAVDFENIDKAPEER MGYG000002234_01026 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus sp900554415|m__MGYG000002234 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,267PG@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002234_01026 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 543874 0 +(Methyl_2H(3)13C(1))AIAAQQNTQFQLANMATQVEAAK MGYG000000077_02467;MGYG000000262_02234 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02467 0.5 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 331962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1305476 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1776800 0 0 0 0 1615341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methyl_2H(3)13C(1))DLIEWVLWNSER MGYG000000243_02761 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1803@1|root,COG1803@2|Bacteria,4NQJ9@976|Bacteroidetes,2FPT5@200643|Bacteroidia,4ANEX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 methylglyoxal synthase 1.0 mgsA 1.0 - 1.0 4.2.3.3 1.0 ko:K01734 1.0 ko00640,ko01120,map00640,map01120 1.0 - 1.0 R01016 1.0 RC00424 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02761 1.0 methylglyoxal synthase. - Does not act on D-glyceraldehyde 3-phosphate.-!-Formerly EC 4.2.99.11. dihydroxyacetone phosphate = methylglyoxal + phosphate. 1.0 1.0 1.0 1.0 Propanoate metabolism|Microbial metabolism in diverse environments 1.0 K01734:mgsA; methylglyoxal synthase [EC:4.2.3.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16235018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32410441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Methylthio)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.1 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2628493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 614736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 852286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 744542 0 0 0 0 0 0 0 0 0 0 0 +(NDA)MLAHLLK MGYG000000038_02185;MGYG000001311_02933;MGYG000003582_01256;MGYG000001558_01857;MGYG000002619_02023;MGYG000003374_01118;MGYG000000771_01164;MGYG000001412_01313;MGYG000000272_02321;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000001763_00396;MGYG000000223_00996;MGYG000001711_02099;MGYG000004732_01055;MGYG000001255_00370;MGYG000001482_02362;MGYG000001496_01122;MGYG000004493_00097;MGYG000000002_02120;MGYG000002194_02222;MGYG000004271_00554;MGYG000002966_00075;MGYG000004317_00142;MGYG000000233_00345;MGYG000001577_01888;MGYG000000174_02692;MGYG000001652_01009;MGYG000000077_00219;MGYG000000127_04855;MGYG000002993_00787;MGYG000002945_00682;MGYG000000229_00395;MGYG000004610_00503;MGYG000002098_00013;MGYG000002212_00259;MGYG000004826_01307;MGYG000001606_02632;MGYG000000213_00374;MGYG000003465_00706;MGYG000001542_01437;MGYG000002517_01026;MGYG000004707_01697;MGYG000000212_01474;MGYG000002126_00535;MGYG000000515_01608;MGYG000001338_02547;MGYG000003074_01265;MGYG000001493_05257;MGYG000004757_01889;MGYG000002141_01131;MGYG000000217_00275;MGYG000001439_00571;MGYG000000280_02459;MGYG000000249_01352;MGYG000003695_01114;MGYG000004691_00618;MGYG000002641_00563;MGYG000000193_03247;MGYG000000140_01181;MGYG000000080_03115;MGYG000002279_00557;MGYG000004799_00704;MGYG000001814_01253;MGYG000003656_01296;MGYG000000242_02076;MGYG000002492_01379;MGYG000000198_04065;MGYG000001334_01647;MGYG000001199_01005;MGYG000001658_00407;MGYG000001688_03910;MGYG000000278_03657;MGYG000001319_00348;MGYG000000495_01130;MGYG000001303_01883;MGYG000000187_02264;MGYG000003504_01686;MGYG000000371_00136;MGYG000004519_00423;MGYG000000097_00328;MGYG000001525_01747;MGYG000000615_00488;MGYG000001423_00991;MGYG000001157_00577;MGYG000000171_00850;MGYG000000195_01135;MGYG000001008_00728;MGYG000000271_03250;MGYG000000562_01218;MGYG000000022_00437;MGYG000000133_02283;MGYG000002298_02410;MGYG000000489_00503;MGYG000004600_00849;MGYG000000399_00360;MGYG000003694_01737;MGYG000001607_01815;MGYG000000230_01325;MGYG000003355_00996;MGYG000000484_01691;MGYG000001710_00672;MGYG000003001_00320;MGYG000000205_02269;MGYG000000145_03615;MGYG000002528_00367;MGYG000004140_01100;MGYG000002188_01071;MGYG000002286_00420;MGYG000000164_00800;MGYG000001748_01525;MGYG000001714_01796;MGYG000002946_02881;MGYG000000150_00838;MGYG000000404_00344;MGYG000004815_01345;MGYG000000141_02825;MGYG000003552_01242;MGYG000003702_00925;MGYG000001781_01334;MGYG000001542_02015;MGYG000002304_00547;MGYG000004740_01468;MGYG000000045_02136;MGYG000000162_00065;MGYG000000089_01653;MGYG000004296_01958;MGYG000002155_00766;MGYG000000179_02084;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000001299_00204;MGYG000000251_00555;MGYG000002992_00164;MGYG000002974_01418;MGYG000002997_01277;MGYG000001237_01808;MGYG000004785_01017;MGYG000002025_02240;MGYG000002963_04095;MGYG000000463_00862;MGYG000001602_01805;MGYG000002052_00078;MGYG000001970_02077;MGYG000004246_01300;MGYG000000153_00303;MGYG000001315_01699;MGYG000001627_00130;MGYG000001469_02299;MGYG000003409_01628;MGYG000003891_00096;MGYG000001310_02090;MGYG000002445_01920;MGYG000000325_00586;MGYG000000909_00644;MGYG000002234_00398;MGYG000003431_01105;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000004809_00788;MGYG000003450_00202;MGYG000003701_01708;MGYG000001954_02254;MGYG000002638_00362;MGYG000000215_01375;MGYG000001065_01088;MGYG000004810_01402;MGYG000000100_02166;MGYG000002131_02428;MGYG000003335_00316;MGYG000000084_01085;MGYG000001300_02008;MGYG000004866_01631;MGYG000003937_01177;MGYG000000252_01324;MGYG000000365_00999;MGYG000000301_01012;MGYG000004722_00591;MGYG000001186_01925;MGYG000004087_02290;MGYG000000312_01508;MGYG000000204_00778;MGYG000003013_01053;MGYG000002857_01020;MGYG000004288_00401;MGYG000000175_00767;MGYG000004714_00143;MGYG000003133_02653;MGYG000000281_02732;MGYG000001619_01736;MGYG000000398_00286;MGYG000001683_01827;MGYG000001421_02311;MGYG000004789_01485;MGYG000003812_01036;MGYG000004735_01946;MGYG000003503_01071;MGYG000004809_00408;MGYG000004593_01977 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.20398009950248755 186801|Clostridia 0.7711442786069652 C 0.5870646766169154 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.47761194029850745 gap 0.9552238805970149 - 0.9154228855721394 1.2.1.12 0.9850746268656716 ko:K00134 0.9850746268656716 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9850746268656716 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9850746268656716 R01061 0.9850746268656716 RC00149 0.9850746268656716 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9850746268656716 - 0.9950248756218906 - 1.0 - 0.9850746268656716 Gp_dh_C,Gp_dh_N 0.9850746268656716 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_02185 0.004975124378109453 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9850746268656716 0.9850746268656716 0.9850746268656716 0.9850746268656716 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9850746268656716 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9850746268656716 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347489 0 0 0 0 90633 +(NHS-LC-Biotin)APEKLRIGFTAYKYDDNFIALYR MGYG000002485_00350 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG1879@1|root,COG1879@2|Bacteria,3793S@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_00350 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(NHS-LC-Biotin)LDGAAQR MGYG000004828_01576;MGYG000002485_02480;MGYG000004893_01506 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004828_01576 0.3333333333333333 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 22997 0 0 0 0 0 0 0 179387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163270 0 0 0 6038920 0 6808774 0 5050459 0 0 0 8756444 0 5199827 0 5940872 0 0 0 0 5485988 3437747 5102728 0 4912086 0 6450491 0 0 5736934 5264007 0 0 5307019 4174418 0 3972792 6511879 5174491 112405 0 27252 0 14422 37072 0 0 0 0 43156 0 82895 0 0 0 0 0 0 0 0 34766 0 0 0 112472 0 0 0 24435 0 0 62782 46559 0 73549 0 0 0 0 0 0 0 0 0 0 0 0 25082 0 63483 0 0 0 0 0 0 0 44230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128244 0 34602 0 81287 48706 76486 0 0 0 0 0 43038 0 0 0 0 0 0 62328 109429 39794 0 0 0 31719 0 0 75511 0 0 0 0 0 0 91487 110350 0 +(NIC[AnyN-term](ICPL)LLIGATNIGR MGYG000001300_00291 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00291 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 274220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1177803 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463364 0 0 0 0 0 0 0 +(NIC[AnyN-term](ICPL)LVEEATAEHPFQFISGLGTTLER MGYG000000243_00124 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1047@1|root,COG1047@2|Bacteria,4NM29@976|Bacteroidetes,2FM08@200643|Bacteroidia,4AKD4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 slyD 1.0 - 1.0 5.2.1.8 1.0 ko:K03775 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 FKBP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00124 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K03775:slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4527052 0 0 0 0 2968812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3155839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(NP40)EHNLTPILC(Carbamidomethyl)C(Carbamidomethyl)GETLEQR MGYG000002517_01028 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01028 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 1029542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1212217 0 0 0 0 0 0 0 0 0 959238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 921889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1840413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2586561 0 0 0 0 0 0 0 0 0 4208327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Phenylisocyanate_2H(5))ADQVDDPELLELVEMEVR MGYG000002994_01317 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Megasphaeraceae|g__Megasphaera|s__Megasphaera sp002319965|m__MGYG000002994 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4H22P@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002994_01317 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 10810158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37301044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5148315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Phenylisocyanate_2H(5))ADVIMILINDEK MGYG000000179_02288 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,21XQ9@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02288 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 419260 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Phenylisocyanate_2H(5))FMASIEAALEKGDVEAAK MGYG000000029_00498;MGYG000001378_04234;MGYG000002281_03613;MGYG000000196_02323;MGYG000001345_03404;MGYG000000013_01747;MGYG000003312_00912;MGYG000002549_04269;MGYG000000098_00597;MGYG000000054_02343 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000029_00498 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449203 0 0 0 0 0 0 0 0 0 0 442462 0 976918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454613 0 0 0 0 0 0 0 0 0 0 490667 0 +(Phenylisocyanate_2H(5))GAGEVVTLDPEESVAYIMGK MGYG000000164_00687 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_00687 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Phenylisocyanate_2H(5))GKGKGSLEYWVAVVKPGR MGYG000002517_02866 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs 1.0 rplP 1.0 - 1.0 - 1.0 ko:K02878 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02866 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02878:RP-L16, MRPL16, rplP; large subunit ribosomal protein L16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 707881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327031 0 0 0 0 0 0 +(Piperidine)AQNNTGFKDHDTGVSPVFAGGVEYAITPEIATR MGYG000003372_01027 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter|s__Citrobacter werkmanii|m__MGYG000003372 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3WWJT@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 M 1.0 OmpA-like transmembrane domain 1.0 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003372_01027 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03286:TC.OOP; OmpA-OmpF porin, OOP family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2854652 0 0 0 0 0 2735637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1154874 0 0 0 0 0 1034010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Piperidine)ERTAKEIEIR MGYG000000031_02186;MGYG000000216_01302 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XZ67@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins 1.0 iscS 1.0 - 1.0 2.8.1.7 1.0 ko:K04487 1.0 ko00730,ko01100,ko04122,map00730,map01100,map04122 1.0 - 1.0 R07460,R11528,R11529 1.0 RC01789,RC02313 1.0 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_02186 0.5 cysteine desulfurase. cysteine desulfurylase. The sulfur from free L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors.-!-The enzyme is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin).-!-In Azotobacter vinelandii, this sulfur provides the inorganic sulfide required for nitrogenous metallocluster formation. [sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine. 1.0 1.0 1.0 1.0 Thiamine metabolism|Metabolic pathways|Sulfur relay system 1.0 K04487:iscS, NFS1; cysteine desulfurase [EC:2.8.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Piperidine)LEHTISNLDNISENTSSAESR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00135 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 695254 0 0 0 0 0 0 0 0 +(Propionamide)AAAPAPKAAAPA MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_00268 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1736316 0 0 0 0 0 0 0 0 0 0 0 0 1876093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)AAELVQALK MGYG000000087_01479;MGYG000000198_02625 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,21YF6@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000087_01479 0.5 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 857005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)AGAVNIVPNSTGAAK MGYG000003409_01628;MGYG000000515_01608;MGYG000002445_01920;MGYG000000325_00586;MGYG000003074_01265;MGYG000001423_00991;MGYG000004735_01946;MGYG000001651_01502;MGYG000000141_02825;MGYG000002025_02240;MGYG000004593_01977;MGYG000001714_01796 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 0.25 186801|Clostridia 0.9166666666666666 G 0.5833333333333334 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 0.9166666666666666 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003409_01628 0.08333333333333333 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 197170 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1003447 0 0 0 0 0 0 0 358986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530878 0 0 0 0 0 0 947598 743097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)AGIALTDTFVK MGYG000003589_01892;MGYG000002540_02142;MGYG000001783_01519;MGYG000003457_01802;MGYG000002057_00658;MGYG000004006_01717;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000002944_01470;MGYG000001345_01069;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002006_01638;MGYG000001749_01249;MGYG000002455_02200;MGYG000001356_02656;MGYG000004487_00117;MGYG000001546_00360;MGYG000000086_02423;MGYG000004726_03349;MGYG000004638_00838;MGYG000000377_02142;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000003681_00790;MGYG000000003_00712;MGYG000002933_02039;MGYG000004482_00387;MGYG000000196_00479;MGYG000003693_00860;MGYG000001661_02632;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000002867_00573;MGYG000000053_01377;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.43859649122807015 976|Bacteroidetes 0.6666666666666666 C 0.5614035087719298 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7719298245614035 gap 0.9473684210526315 - 1.0 1.2.1.12 0.9649122807017544 ko:K00134 0.9649122807017544 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9649122807017544 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9649122807017544 R01061 0.9649122807017544 RC00149 0.9649122807017544 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9649122807017544 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 0.9649122807017544 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003589_01892 0.017543859649122806 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9649122807017544 0.9649122807017544 0.9649122807017544 0.9649122807017544 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9649122807017544 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9649122807017544 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3071230 0 0 0 0 2082738 0 0 0 0 0 0 1848836 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2900067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2647601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)AGVPADQVDHVYMGCVIQAGLGQNVAR MGYG000002528_02664;MGYG000000164_00683;MGYG000000501_00162;MGYG000000028_00940;MGYG000000690_01881;MGYG000004359_01902 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.6666666666666666 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02664 0.16666666666666666 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1469125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)AIGIPEEELR MGYG000003202_00622 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__UBA3263|s__UBA3263 sp900759865|m__MGYG000003202 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,4AKYT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003202_00622 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9827384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)AIGIPEEELRK MGYG000001871_00441 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__|s__|m__MGYG000001871 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,4AKYT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001871_00441 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3413234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)AKEKFER MGYG000000042_01421;MGYG000002106_00224;MGYG000001524_01606;MGYG000001630_01142;MGYG000002485_02622;MGYG000004893_01944;MGYG000004893_00932;MGYG000003460_01161;MGYG000003155_00314;MGYG000001925_01419;MGYG000000273_00431;MGYG000001701_00473;MGYG000004763_01689;MGYG000003681_02037;MGYG000001384_04567;MGYG000001464_00103;MGYG000002281_02290;MGYG000003185_01074;MGYG000003992_01709;MGYG000003142_01879;MGYG000002528_01098;MGYG000001313_00097;MGYG000000013_02251;MGYG000003266_00392;MGYG000003583_01411;MGYG000002455_03884;MGYG000000348_00283;MGYG000003628_01000;MGYG000001485_02164;MGYG000000034_01346;MGYG000001141_02439;MGYG000002930_00867;MGYG000003142_01865;MGYG000000196_03974;MGYG000003375_00698;MGYG000004573_00004;MGYG000001661_02666;MGYG000003851_00676;MGYG000002762_01733;MGYG000000121_02189;MGYG000001789_00154;MGYG000001567_01738;MGYG000000182_00585;MGYG000000054_03933;MGYG000000236_01807;MGYG000000098_02017;MGYG000002291_02272;MGYG000003185_01053;MGYG000002556_01332;MGYG000000036_01380;MGYG000000445_01370;MGYG000001346_01533;MGYG000000243_01988;MGYG000001780_03476;MGYG000002540_03367;MGYG000001646_01118;MGYG000003073_01160;MGYG000003514_00785;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.23728813559322035 976|Bacteroidetes 0.4915254237288136 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9830508474576272 tuf 1.0 - 0.847457627118644 - 1.0 ko:K02358 0.9830508474576272 - 0.9830508474576272 - 0.9830508474576272 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9830508474576272 - 0.9830508474576272 - 1.0 - 0.9491525423728814 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.01694915254237288 - - - - 1.0 1.0 1.0 1.0 - 0.9830508474576272 K02358:tuf, TUFM; elongation factor Tu 0.9830508474576272 none 1.0 0 0 1240537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133338 1279505 0 0 0 0 642122 0 0 136093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365959 117514 0 0 0 0 79448 0 0 430732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247889 271666 0 0 0 0 277753 0 0 292060 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216293 156941 0 0 0 0 266723 0 0 58577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320510 0 0 0 0 0 364122 +(Propionamide)ALAQVEK MGYG000003683_00219 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0468@1|root,COG0468@2|Bacteria,2GJ4P@201174|Actinobacteria,4CYYY@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 L 1.0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage 1.0 recA 1.0 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 1.0 - 1.0 ko:K03553 1.0 ko03440,map03440 1.0 M00729 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03400 1.0 - 1.0 - 1.0 - 1.0 ABC2_membrane,Intein_splicing,LAGLIDADG_2,LAGLIDADG_3,Rad51,RecA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00219 1.0 - - - - 1.0 1.0 1.0 1.0 Homologous recombination 1.0 K03553:recA; recombination protein RecA 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1988227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)ALEAGVNQLADTVR MGYG000000080_01156;MGYG000000077_00451;MGYG000003486_00745;MGYG000001607_00737;MGYG000001619_01799;MGYG000000146_01484;MGYG000004317_02207;MGYG000002528_02459;MGYG000001714_01961;MGYG000003239_01867;MGYG000000179_05119;MGYG000001683_01057;MGYG000002445_00865;MGYG000000217_01904;MGYG000001531_01706;MGYG000000242_00061;MGYG000001065_00812;MGYG000004087_02347;MGYG000003828_02241;MGYG000000262_01443;MGYG000002279_00394;MGYG000000909_02638;MGYG000001707_02383 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2681F@186813|unclassified Clostridiales 0.30434782608695654 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000080_01156 0.043478260869565216 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)ALLHVAK MGYG000002494_03016 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1249@1|root,COG1249@2|Bacteria,1MU2U@1224|Proteobacteria,1RMFF@1236|Gammaproteobacteria,3XM8F@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes 1.0 lpdA 1.0 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006103,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006544,GO:0006546,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015036,GO:0016054,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017144,GO:0018130,GO:0019438,GO:0019464,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045250,GO:0045254,GO:0046390,GO:0046395,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0065007,GO:0065008,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.0 1.8.1.4 1.0 ko:K00382 1.0 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00036,M00307,M00532 1.0 R00209,R01221,R01698,R03815,R07618,R08549 1.0 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 1.0 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_1869,iEcolC_1368.EcolC_3543,iPC815.YPO3417,iSFV_1184.SFV_0107,iUMN146_1321.UM146_23385 1.0 Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03016 1.0 dihydrolipoyl dehydrogenase. L-protein. A component of the multienzyme 2-oxo-acid dehydrogenase complexes.-!-In the pyruvate dehydrogenase complex, it binds to the core of EC 2.3.1.12 and catalyzes oxidation of its dihydrolipoyl groups.-!-It plays a similar role in the oxoglutarate and 3-methyl-2- oxobutanoate dehydrogenase complexes.-!-Another substrate is the dihydrolipoyl group in the H-protein of the glycine-cleavage system, in which it acts, together with EC 1.4.4.2 and EC 2.1.2.10 to break down glycine.-!-It can also use free dihydrolipoate, dihydrolipoamide or dihydrolipoyllysine as substrate.-!-Was first shown to catalyze the oxidation of NADH by methylene blue; this activity was called diaphorase.-!-The glycine cleavage system is composed of four components that only loosely associate: the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H protein.-!-Formerly EC 1.6.4.3. N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = H(+) + N(6)-[(R)- lipoyl]-L-lysyl-[protein] + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Glycine, serine and threonine metabolism|Valine, leucine and isoleucine degradation|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00382:DLD, lpd, pdhD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 941562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)ALSATDGDMDKAVEFLR MGYG000000205_00610;MGYG000000255_00470 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,21ZJJ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_00610 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)ATDGILAR MGYG000004797_01549 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0427@1|root,COG0427@2|Bacteria,4NFS3@976|Bacteroidetes,2FNCA@200643|Bacteroidia,4AM99@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG0427 Acetyl-CoA hydrolase 1.0 scpC 1.0 - 1.0 2.8.3.18,3.1.2.1 1.0 ko:K01067,ko:K18118 1.0 ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011 1.0 R00227,R10343 1.0 RC00004,RC00012,RC00014 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01549 1.0 succinyl-CoA:acetate CoA-transferase. | acetyl-CoA hydrolase. SCACT. | acetyl-CoA deacylase. In some bacteria the enzyme catalyzes the conversion of acetate to acetyl-CoA as part of a modified tricarboxylic acid (TCA) cycle.-!-In other organisms it converts acetyl-CoA to acetate during fermentation.-!-In some organisms the enzyme also catalyzes the activity of EC 2.8.3.27. acetate + succinyl-CoA = acetyl-CoA + succinate. | acetyl-CoA + H2O = acetate + CoA + H(+). 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01067:E3.1.2.1, ACH1; acetyl-CoA hydrolase [EC:3.1.2.1]|K18118:aarC, cat1; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 440579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 852667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2087756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2903803 0 0 0 0 0 0 +(Propionamide)AVDDKVLAALAK MGYG000001315_01172 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 2.2.1.2,5.3.1.9 1.0 ko:K01810,ko:K13810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00004,M00007,M00114 1.0 R01827,R02739,R02740,R03321 1.0 RC00376,RC00439,RC00563,RC00604 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01172 1.0 transaldolase. | glucose-6-phosphate isomerase. glycerone transferase. | phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]|K13810:tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)AYVDAK MGYG000002478_03973 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,2FNN5@200643|Bacteroidia,4AP04@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG0058 Glucan phosphorylase 1.0 glgP 1.0 - 1.0 2.4.1.1,2.4.1.11,2.4.1.8 1.0 ko:K00688,ko:K00691,ko:K16153 1.0 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 1.0 - 1.0 R00292,R01555,R02111 1.0 RC00005,RC00049 1.0 ko00000,ko00001,ko01000,ko01003 1.0 - 1.0 GH65,GT3,GT35 1.0 - 1.0 DUF3417,Glycogen_syn,Phosphorylase 1.0 2.4.1.1 1.0 GT35 1.0 GT35 1.0 GT35 1.0 MGYG000002478_03973 1.0 glycogen phosphorylase. | glycogen(starch) synthase. | maltose phosphorylase. polyphosphorylase. | UDP-glucose--glycogen glucosyltransferase. This entry covers several enzymes from different sources that act in vivo on different forms of (1->4)-alpha-D-glucans.-!-Some of these enzymes catalyze the first step in the degradation of large branched glycan polymers - the phosphorolytic cleavage of alpha-1,4-glucosidic bonds from the non-reducing ends of linear poly(1->4)-alpha-D-glucosyl chains within the polymers.-!-The enzyme stops when it reaches the fourth residue away from an alpha-1,6 branching point, leaving a highly branched core known as a limit dextrin.-!-The description (accepted name) of the enzyme should be modified for each specific instance by substituting 'glycogen' with the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, etc. | The description (official name) varies according to the source of the enzyme and the nature of its synthetic product.-!-Glycogen synthase from animal tissues is a complex of a catalytic subunit and the protein glycogenin.-!-The enzyme requires glucosylated glycogenin as a primer; this is the reaction product of EC 2.4.1.186.-!-A similar enzyme utilizes ADP-glucose (cf. EC 2.4.1.21). [(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. | [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D- glucosyl](n+1) + H(+) + UDP. | D-maltose + phosphate = beta-D-glucose 1-phosphate + D-glucose. 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biofilm formation - Escherichia coli|Necroptosis|Insulin signaling pathway|Glucagon signaling pathway|Insulin resistance 1.0 K00688:PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]|K00691:mapA; maltose phosphorylase [EC:2.4.1.8]|K16153:K16153; glycogen phosphorylase/synthase [EC:2.4.1.1 2.4.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3488127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)CDAFNAAHPNWDLTFK MGYG000001319_02248 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia,4BYAS@830|Butyrivibrio 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001319_02248 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K15770:cycB, ganO, mdxE; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9707100 0 0 0 0 12124811 0 0 0 0 13445799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)DAEALKK MGYG000001619_00896 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA9502|s__UBA9502 sp900540335|m__MGYG000001619 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001619_00896 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1453562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)DAVLTAK MGYG000003693_01161 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG1546@1|root,COG1546@2|Bacteria,4NDVV@976|Bacteroidetes,2FMFI@200643|Bacteroidia,4APD5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Belongs to the CinA family 1.0 cinA 1.0 - 1.0 3.5.1.42 1.0 ko:K03742,ko:K03743 1.0 ko00760,map00760 1.0 - 1.0 R02322 1.0 RC00100 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CinA,MoCF_biosynth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_01161 1.0 nicotinamide-nucleotide amidase. - Also acts more slowly on beta-nicotinamide D-ribonucleoside. beta-nicotinamide D-ribonucleotide + H2O = NH4(+) + nicotinate beta-D- ribonucleotide. 1.0 1.0 1.0 1.0 Nicotinate and nicotinamide metabolism 1.0 K03742:pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]|K03743:pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20501219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)DELGVKGAFTSAGMDGSSDWR MGYG000000201_01623 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066145|m__MGYG000000201 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3XZHY@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 GH49 1.0 MGYG000000201_01623 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2357966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)DGAFKDEIVPVVIKGK MGYG000002274_00043;MGYG000001300_00296;MGYG000003937_01092;MGYG000002619_02240 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_00043 0.25 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)DGEMEYGVGIHGEPGIQR MGYG000000050_00164 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066505|m__MGYG000000050 1.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,36E0T@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Dihydroxyacetone kinase DhaK, subunit 1.0 dhaK 1.0 - 1.0 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 1.0 ko:K00863,ko:K05878 1.0 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 1.0 M00344 1.0 R01011,R01012,R01059 1.0 RC00002,RC00015,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak1,Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000050_00164 1.0 phosphoenolpyruvate--glycerone phosphotransferase. | triokinase. | glycerone kinase. | FAD-AMP lyase (cyclizing). triose kinase. | dihydroxyacetone kinase. | FMN cyclase. While FAD was the best substrate tested the enzyme also splits ribonucleoside diphosphate-X compounds in which X is an acyclic or cyclic monosaccharide or derivative bearing an X-OH group that is able to attack internally the proximal phosphorus with the geometry necessary to form a P=X product; either a five-atom monocyclic phosphodiester or a cis-bicyclic phosphodiester-pyranose fusion.-!-The reaction is strongly inhibited by ADP or ATP but is unaffected by the presence of the product, cFMN. dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. | ATP + D-glyceraldehyde = ADP + D-glyceraldehyde 3-phosphate + H(+). | ATP + dihydroxyacetone = ADP + dihydroxyacetone phosphate + H(+). | FAD = AMP + H(+) + riboflavin cyclic-4',5'-phosphate. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Glycerolipid metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|RIG-I-like receptor signaling pathway 1.0 K00863:DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]|K05878:dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9828999 0 0 4586331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6626574 0 9065325 0 0 0 0 0 0 0 0 12879149 0 0 0 0 7305238 +(Propionamide)DIGLTDADLAGQYQYTK MGYG000000022_00102 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00102 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1119888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)DSGCNVIIGLYEGSK MGYG000001315_02512;MGYG000004740_00571;MGYG000002492_01825;MGYG000002670_02165 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,25VBQ@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 H 0.75 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 0.75 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_02512 0.25 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1565089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1617591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)EALHILK MGYG000002171_00028;MGYG000000243_00429 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0156@1|root,COG0156@2|Bacteria,4NJ3B@976|Bacteroidetes,2G2VS@200643|Bacteroidia,4AW5T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.3.1.47 1.0 ko:K00652 1.0 ko00780,ko01100,map00780,map01100 1.0 M00123,M00573,M00577 1.0 R03210,R10124 1.0 RC00004,RC00039,RC02725 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 AMP-binding,AMP-binding_C,Aminotran_1_2,PP-binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_00028 0.5 8-amino-7-oxononanoate synthase. AONS. The enzyme catalyzes the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis.-!-Pimeloyl-CoA can be used with lower efficiency. 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]. 1.0 1.0 1.0 1.0 Biotin metabolism|Metabolic pathways 1.0 K00652:bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] 1.0 none 1.0 618439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 817154 0 0 0 0 0 0 0 0 0 0 708267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 839412 0 0 0 0 0 0 0 0 0 0 1126607 0 6191722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7424762 0 0 0 0 0 0 0 0 0 0 9259566 0 3702087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2189435 0 0 0 0 0 0 0 0 0 0 3009733 0 +(Propionamide)EGINEAMK MGYG000001683_01827 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Frisingicoccus|s__|m__MGYG000001683 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001683_01827 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1833902 0 0 0 0 0 0 +(Propionamide)ELFNLR MGYG000000087_00997;MGYG000002040_00978;MGYG000004714_00674;MGYG000001365_00966;MGYG000003921_00351;MGYG000003166_00767;MGYG000002965_00666;MGYG000001748_00602;MGYG000000249_01543;MGYG000003899_00622;MGYG000004271_00024;MGYG000001636_00354;MGYG000000177_02168;MGYG000000133_00053;MGYG000001602_00388;MGYG000002393_00687;MGYG000002279_01064;MGYG000000184_01180;MGYG000000136_02070;MGYG000000251_01823;MGYG000001488_02376;MGYG000002272_00459;MGYG000004681_00019;MGYG000002945_02576;MGYG000004285_00578;MGYG000001607_01093;MGYG000001642_00142;MGYG000004733_00976;MGYG000001423_01146;MGYG000002619_02378;MGYG000004158_01539;MGYG000002670_00394;MGYG000003693_01253;MGYG000004769_00447;MGYG000000204_02168;MGYG000000159_01019;MGYG000002395_00358;MGYG000000195_02125;MGYG000000515_01667;MGYG000002517_02865;MGYG000002304_02163;MGYG000002557_00162;MGYG000000301_00168;MGYG000002978_01111;MGYG000001300_02207;MGYG000000193_02104;MGYG000002791_01000;MGYG000001652_00830;MGYG000000217_01262;MGYG000001292_02354;MGYG000000268_01519;MGYG000002202_01351;MGYG000002528_01847;MGYG000002074_00244;MGYG000004630_00943;MGYG000002772_00329;MGYG000001338_02799;MGYG000000233_02351;MGYG000003486_01262;MGYG000001567_01817;MGYG000000198_04895;MGYG000002445_01504;MGYG000000802_00715;MGYG000000255_01832;MGYG000004783_00291;MGYG000000039_01693;MGYG000001315_01344;MGYG000000194_02274;MGYG000000092_00988;MGYG000000140_01891;MGYG000002274_00837;MGYG000000325_01670;MGYG000003683_01130;MGYG000004894_01025;MGYG000000200_01105;MGYG000000911_00432;MGYG000000262_00154;MGYG000003459_00664;MGYG000004894_00604;MGYG000000693_00199;MGYG000000028_01614;MGYG000002968_01155;MGYG000002963_00446;MGYG000003422_00858;MGYG000000022_02032;MGYG000002702_01359;MGYG000003425_03563;MGYG000000420_00594;MGYG000004851_00265;MGYG000000258_00289;MGYG000002065_01091;MGYG000000562_01922;MGYG000002919_00423;MGYG000003937_00259;MGYG000000756_00960;MGYG000003074_00527;MGYG000002756_00361;MGYG000000084_01010;MGYG000000036_00617;MGYG000000281_01467;MGYG000000392_01453;MGYG000002998_00178;MGYG000000038_01584;MGYG000000312_01456;MGYG000000243_00039;MGYG000000271_01069;MGYG000002560_02573;MGYG000004140_01823;MGYG000002966_02567;MGYG000001707_02038;MGYG000004039_00542;MGYG000001627_01320;MGYG000000119_00093;MGYG000004558_00368;MGYG000003266_00868;MGYG000000080_02263;MGYG000003465_00835;MGYG000003922_01732;MGYG000000213_00206;MGYG000001439_02151;MGYG000000489_01450;MGYG000002545_01132;MGYG000000484_00183;MGYG000002459_00387;MGYG000002469_01761;MGYG000001645_00448;MGYG000004869_03328;MGYG000000245_02646;MGYG000000989_00148;MGYG000001814_02459;MGYG000003147_00988;MGYG000002641_00980;MGYG000004718_00070;MGYG000002651_00740;MGYG000003452_00880;MGYG000000417_00386;MGYG000004681_01725;MGYG000000206_01042;MGYG000001496_03128;MGYG000002492_00383;MGYG000004716_01214;MGYG000000002_00874;MGYG000001543_00409;MGYG000001374_01188;MGYG000000179_04592;MGYG000004642_00859;MGYG000001255_02125;MGYG000004762_01326 domain d__Bacteria 1.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae 0.20270270270270271 186801|Clostridia 0.7702702702702703 J 0.9594594594594594 Belongs to the universal ribosomal protein uL29 family 0.8108108108108109 rpmC 0.9391891891891891 - 0.918918918918919 - 0.9662162162162162 ko:K02904 0.9391891891891891 ko03010,map03010 0.9594594594594594 M00178,M00179 0.9391891891891891 - 0.972972972972973 - 0.972972972972973 br01610,ko00000,ko00001,ko00002,ko03011 0.9594594594594594 - 1.0 - 0.9797297297297297 - 1.0 Ribosomal_L29 0.918918918918919 - 0.9864864864864865 - 0.9797297297297297 - 0.9797297297297297 - 0.9797297297297297 MGYG000000087_00997 0.006756756756756757 - - - - 0.9662162162162162 0.9662162162162162 0.9662162162162162 0.9662162162162162 Ribosome 0.9594594594594594 K02904:RP-L29, rpmC; large subunit ribosomal protein L29 0.9391891891891891 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775214 0 0 0 0 0 0 +(Propionamide)EQNAAAADPNWK MGYG000000074_02571 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG4772@1|root,COG4772@2|Bacteria,4NEJW@976|Bacteroidetes,2G3F5@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02571 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1861050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)ESVNVPAGK MGYG000000099_01985 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0860@1|root,COG0860@2|Bacteria,1UMXD@1239|Firmicutes,25GRN@186801|Clostridia,26CS5@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 M 1.0 S-layer homology domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_01985 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5330795 0 0 0 0 0 0 1578702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1790407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)FCLDDNDANTPR MGYG000000074_00675 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1409@1|root,COG1409@2|Bacteria,4PNR4@976|Bacteroidetes,2FZJW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Putative binding domain, N-terminal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BACON 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00675 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5584054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5170962 0 0 0 0 0 0 +(Propionamide)FEPDTIIALGGGSAMDAGK MGYG000001310_00117 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_00117 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)FVTPVGPYFK MGYG000000196_04103;MGYG000001345_01382;MGYG000000243_02172;MGYG000002478_00294 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,2FMPE@200643|Bacteroidia,4AMTS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase 1.0 ilvE 1.0 - 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04103 0.25 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Valine, leucine and isoleucine degradation|Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00826:E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GDDPNTAWEK MGYG000000271_00306;MGYG000002025_00961;MGYG000002989_01139;MGYG000000142_02730;MGYG000004733_02765;MGYG000000909_01068;MGYG000000133_00505;MGYG000000216_01908;MGYG000001338_01295;MGYG000001619_00079;MGYG000004740_00559;MGYG000002517_01687;MGYG000000262_01833;MGYG000000301_00648;MGYG000000198_05682 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,25V1D@186806|Eubacteriaceae 0.9333333333333333 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.9333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00306 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1087589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GDKIVQM(Oxidation)NYDAIDAGAK MGYG000001315_01946;MGYG000001496_03305 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,27VFG@189330|Dorea 0.5 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001315_01946 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1048292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GDKIVQMNYDAIDAGAK MGYG000001315_01946;MGYG000001496_03305 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,27VFG@189330|Dorea 0.5 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001315_01946 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6097800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GFDGDNTPIIR MGYG000000446_00437 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__RF39|f__UBA660|g__UMGS1045|s__UMGS1045 sp900547995|m__MGYG000000446 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,3VNVP@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000446_00437 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1158458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GFYPDGK MGYG000000217_02614;MGYG000000018_02138 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000217_02614 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14069695 0 0 0 0 16905229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 804867 0 0 0 0 604698 0 0 0 0 643884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 510162 0 0 0 0 481748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 600625 0 0 0 0 279299 0 0 0 0 306890 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GGAEFMDYSMIDKAPEER MGYG000001365_00649;MGYG000003868_01133;MGYG000003868_01166;MGYG000004769_00412;MGYG000002659_00459;MGYG000004769_00437 family d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4H22P@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001365_00649 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GHYAVPAANIVNLENIK MGYG000002528_01589 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0191@1|root,COG0191@2|Bacteria,1TRQY@1239|Firmicutes,24DXB@186801|Clostridia,36VQR@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Fructose-bisphosphate aldolase class-II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01589 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 115250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185139 0 0 0 0 0 0 0 489240 429911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10638822 0 0 0 0 227540 0 0 886995 375431 0 0 0 0 586031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742028 340586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 118107 0 0 0 0 0 0 853190 0 0 840140 536285 0 0 0 0 0 0 0 0 0 0 218268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GIPIIADGGIK MGYG000001338_00214;MGYG000004785_01919 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_00214 0.5 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GLNVADVPR MGYG000001496_01244 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Extibacter|s__Extibacter sp001185345|m__MGYG000001496 1.0 COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,24BF2@186801|Clostridia,2209B@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Peptidase family M20/M25/M40 1.0 amaB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001496_01244 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GLSKEELASGDYSK MGYG000003351_05248 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900765785|m__MGYG000003351 1.0 COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,2FNWR@200643|Bacteroidia,4ANEE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 COG COG1082 Sugar phosphate isomerases epimerases 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003351_05248 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1074775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GQYIKSATLTSTMGPGVK MGYG000002670_00356 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp900546625|m__MGYG000002670 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002670_00356 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GTSAPEFTLVK MGYG000002478_04382 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG2077@1|root,COG2077@2|Bacteria,4NNGR@976|Bacteroidetes,2FSI3@200643|Bacteroidia,4AMD1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides 1.0 tpx 1.0 - 1.0 1.11.1.15 1.0 ko:K11065 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Redoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_04382 1.0 and 1.11.1.29. - - - 1.0 1.0 1.0 1.0 - 1.0 K11065:tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4254092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GTTAESLAGLR MGYG000002528_02664 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02664 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12267377 0 0 0 3529805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7520176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9643749 3791346 0 0 1905166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3623681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4646338 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)GVDKNEIKR MGYG000000196_03974;MGYG000000236_01807;MGYG000004763_01689;MGYG000000013_02251;MGYG000002281_02290 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_03974 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1371303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)IAAFQNTQFELAEMK MGYG000000195_01571 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_E|m__MGYG000000195 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WI1F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000195_01571 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 634169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1461983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)IGGGMGC(Carbamidomethyl)STIVERD MGYG000000262_02231;MGYG000000077_02464;MGYG000002517_00540 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 0.6666666666666666 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02231 0.3333333333333333 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2205336 0 4289485 0 0 1976983 0 0 2335792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3282563 3141873 0 0 0 0 0 0 1797934 0 0 3965450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)IGSIAQMATMR MGYG000003701_02275 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides sp003480915|m__MGYG000003701 1.0 COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,2FMB3@200643|Bacteroidia,22WM9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Myo-inositol-1-phosphate synthase 1.0 ino1 1.0 - 1.0 5.5.1.4 1.0 ko:K01858 1.0 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 1.0 - 1.0 R07324 1.0 RC01804 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Inos-1-P_synth,NAD_binding_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003701_02275 1.0 inositol-3-phosphate synthase. myo-inositol-1-phosphate synthase. The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the -CHO at C-1; finally, the enzyme-bound NADH reconverts C-5 into the -CHOH- form. D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. 1.0 1.0 1.0 1.0 Streptomycin biosynthesis|Inositol phosphate metabolism|Metabolic pathways 1.0 K01858:INO1, ISYNA1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 526411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1580154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)IGVLAAYYTDGTTITK MGYG000000003_01533 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 2DX4F@1|root,343BI@2|Bacteria,4P5MZ@976|Bacteroidetes,2FVJX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_01533 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 1428652 0 0 1365363 0 0 0 0 0 1333680 0 0 0 0 0 1973648 0 0 0 0 0 0 0 0 1312218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 619053 0 0 741147 0 0 0 0 0 631012 0 0 0 0 0 697001 0 0 0 0 0 0 0 0 905461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)IMNPDDKAGLEAALR MGYG000001637_02230;MGYG000004740_00274;MGYG000000087_01268;MGYG000001367_03001;MGYG000002067_00419;MGYG000001615_04300;MGYG000000164_00687;MGYG000003074_00586;MGYG000002141_01824;MGYG000000255_01557;MGYG000001315_01867;MGYG000000489_01026;MGYG000001617_02046;MGYG000000018_00072;MGYG000000077_02468;MGYG000002278_01894;MGYG000004719_02002;MGYG000004055_00051;MGYG000000997_00555;MGYG000000127_04021;MGYG000001777_01059;MGYG000000312_02426;MGYG000001809_02343;MGYG000002445_02276;MGYG000002945_00738;MGYG000003801_01544;MGYG000002528_02668;MGYG000003702_03102;MGYG000001749_01451;MGYG000004359_01906;MGYG000000028_00944;MGYG000000271_02101;MGYG000000404_01798;MGYG000000398_00614;MGYG000002492_00660;MGYG000000154_01281;MGYG000002517_00543;MGYG000004762_01002;MGYG000000262_02235;MGYG000003381_01959;MGYG000003486_02521;MGYG000001319_02234 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.4523809523809524 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.4523809523809524 etfB 1.0 - 0.9047619047619048 - 0.8333333333333334 ko:K03521 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.8333333333333334 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.023809523809523808 - - - - 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.8333333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1417897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)IPHVEIVR MGYG000000668_02273 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Anaerovoracaceae|g__CAG-238|s__CAG-238 sp900551415|m__MGYG000000668 1.0 COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,25UUF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 E 1.0 Lysine-2,3-aminomutase 1.0 kamA 1.0 - 1.0 5.4.3.2 1.0 ko:K01843 1.0 ko00310,map00310 1.0 - 1.0 R00461 1.0 RC00303 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,LAM_C,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000668_02273 1.0 lysine 2,3-aminomutase. - This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-It contains pyridoxal phosphate and a [4Fe-4S] cluster and binds an exchangeable S-adenosyl-L-methionine molecule.-!-Activity in vitro requires a strong reductant such as dithionite and strictly anaerobic conditions.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of S-adenosyl-L-methionine, mediated by the iron- sulfur cluster.-!-S-adenosyl-L-methionine is regenerated at the end of the reaction. L-lysine = (3S)-3,6-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K01843:kamA; lysine 2,3-aminomutase [EC:5.4.3.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1230475 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)ISEEIGKTPVQVEEAAGFVVNR MGYG000004604_00971;MGYG000000233_02444;MGYG000000164_00685;MGYG000000255_01554;MGYG000002945_00736;MGYG000000087_01270 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,27IK9@186928|unclassified Lachnospiraceae 0.6666666666666666 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 0.6666666666666666 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004604_00971 0.16666666666666666 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 3851068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3336254 0 0 0 0 0 0 3335122 5519113 1983954 0 0 0 0 2065659 330979 1148166 0 0 0 675983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459245 0 977971 0 0 0 0 0 0 1367651 391540 560358 0 296039 0 0 0 910554 788028 424304 0 0 0 0 1011924 0 0 0 0 0 0 0 0 0 0 0 940080 0 0 0 0 0 929256 0 0 0 0 0 0 0 0 1653015 0 0 616808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)IVDAIPYVESER MGYG000004667_05620 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium|s__Clostridium beijerinckii|m__MGYG000004667 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,36EFE@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004667_05620 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7959231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)LATGEKLGAFALTEPGAGTDAQGAQTK MGYG000000271_02102;MGYG000002517_00542;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02102 0.3333333333333333 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 839129 0 0 0 0 0 1431895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)LIIADLNR MGYG000000312_01941 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eisenbergiella|s__Eisenbergiella sp900539715|m__MGYG000000312 1.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,27IZN@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 - 1.0 - 1.0 ko:K03695,ko:K03696 1.0 ko01100,ko04213,map01100,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N,UVR 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 MGYG000000312_01941 1.0 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways|Longevity regulating pathway - multiple species 1.0 K03695:clpB; ATP-dependent Clp protease ATP-binding subunit ClpB|K03696:clpC; ATP-dependent Clp protease ATP-binding subunit ClpC 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)LPKTGVVAK MGYG000000217_02552 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Acetatifactor|s__Acetatifactor sp900066565|m__MGYG000000217 1.0 COG0493@1|root,COG0543@1|root,COG0493@2|Bacteria,COG0543@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,36E1P@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 glutamate synthase (NADPH), homotetrameric 1.0 gltA 1.0 - 1.0 1.17.1.9,1.4.1.13,1.4.1.14 1.0 ko:K00123,ko:K00266 1.0 ko00250,ko00630,ko00680,ko00910,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00250,map00630,map00680,map00910,map01100,map01110,map01120,map01130,map01200,map01230 1.0 - 1.0 R00093,R00114,R00248,R00519 1.0 RC00006,RC00010,RC02796,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fer2_4,Fer4,Fer4_20,Molybdop_Fe4S4,Molybdopterin,NAD_binding_1,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000217_02552 1.0 formate dehydrogenase. | glutamate synthase (NADPH). | glutamate synthase (NADH). NAD(+)-formate dehydrogenase. | NADPH-glutamate synthase. | NADH-glutamate synthase. The enzyme from most aerobic organisms is devoid of redox-active centers but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centers, flavin and a molybdenum center.-!-Together with EC 1.12.1.2, forms a system previously known as formate hydrogenlyase.-!-Formerly EC 1.2.1.2. | The reaction takes place in the opposite direction.-!-The protein is composed of two subunits, alpha and beta.-!-The alpha subunit is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.4).-!-The beta subunit transfers electrons from the cosubstrate.-!-The NH3 is channeled through a 31 A channel in the active protein.-!-In the absence of the beta subunit, coupling between the two domains of the alpha subunit is compromised and some ammonium can be produced.-!-In the intact alphabeta complex, ammonia production only takes place as part of the overall reaction.-!-Formerly EC 2.6.1.53. | A flavoprotein (FMN).-!-The reaction takes place in the direction of L-glutamate production.-!-The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2). formate + NAD(+) = CO2 + NADH. | 2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH. | 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Glyoxylate and dicarboxylate metabolism|Methane metabolism|Nitrogen metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00123:fdoG, fdhF, fdwA; formate dehydrogenase major subunit [EC:1.17.1.9]|K00266:gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1442493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)LPLALK MGYG000000127_00702;MGYG000000133_00543;MGYG000000301_01106 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 E 0.6666666666666666 Psort location CytoplasmicMembrane, score 10.00 0.6666666666666666 agcS 0.6666666666666666 - 1.0 - 0.6666666666666666 ko:K03310 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 ko00000 0.6666666666666666 2.A.25 0.6666666666666666 - 1.0 - 1.0 Na_Ala_symp 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000127_00702 0.3333333333333333 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 - 0.6666666666666666 K03310:TC.AGCS; alanine or glycine:cation symporter, AGCS family 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1084924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)LQNDFTGVLTGK MGYG000003455_00764 genome d__Archaea|p__Thermoplasmatota|c__Thermoplasmata|o__Methanomassiliicoccales|f__Methanomethylophilaceae|g__UBA71|s__UBA71 sp900767505|m__MGYG000003455 1.0 COG0334@1|root,arCOG01352@2157|Archaea,2XU0F@28890|Euryarchaeota,3F2GY@33867|unclassified Euryarchaeota 1.0 28890|Euryarchaeota 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 1.4.1.2,1.4.1.3,1.4.1.4 1.0 ko:K00260,ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003455_00764 1.0 glutamate dehydrogenase. | glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). | (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Taurine and hypotaurine metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00260:gudB, rocG; glutamate dehydrogenase [EC:1.4.1.2]|K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)LSTTITGLEMFR MGYG000003166_01350;MGYG000000022_02283;MGYG000002224_01123;MGYG000002040_01212;MGYG000002272_01482 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_01350 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 552144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394356 0 0 0 0 266690 0 0 172748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)LYEALEGC(Carbamidomethyl)PVTIR MGYG000000417_00539;MGYG000000153_02081;MGYG000000280_02154;MGYG000004810_00381;MGYG000000154_00436;MGYG000002670_01671;MGYG000004517_00262;MGYG000003307_01519;MGYG000000392_01615;MGYG000001756_01779;MGYG000000404_01435;MGYG000002492_01692;MGYG000001652_01307;MGYG000002517_01243;MGYG000000489_00801;MGYG000001637_01169;MGYG000003694_01656;MGYG000003422_01232 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 0.5 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8333333333333334 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000417_00539 0.05555555555555555 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1036002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)MAQLALGMVETR MGYG000000268_01898 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Schaedlerella|s__Schaedlerella sp900066545|m__MGYG000000268 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000268_01898 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1319156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)MVVQHNLTAM(Oxidation)NANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.1 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.1 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 903892 1203227 0 2847612 0 656978 2515732 0 746584 0 0 2120241 0 0 0 0 0 0 0 0 0 665848 0 1730909 0 0 2030679 0 0 912978 0 0 0 0 0 887586 879951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032376 655484 0 1569731 0 657194 267204 0 785072 0 0 856521 0 0 0 0 0 0 0 0 0 104490 0 402527 0 558656 275150 0 0 984576 0 0 0 0 0 680520 999507 0 +(Propionamide)NGAILITTK MGYG000000196_00769 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG1629@1|root,COG4774@1|root,COG1629@2|Bacteria,COG4774@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4AWE8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00769 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2464228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)NIPGVK MGYG000000080_02256;MGYG000001781_02370;MGYG000000036_00624;MGYG000000045_02210;MGYG000004158_01532;MGYG000000255_02599;MGYG000002857_00040;MGYG000004727_00006;MGYG000003937_00266;MGYG000001319_01323;MGYG000002777_00388;MGYG000003453_00779 domain d__Bacteria 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,36DFP@31979|Clostridiaceae 0.3333333333333333 186801|Clostridia 0.75 J 0.9166666666666666 Forms part of the polypeptide exit tunnel 0.9166666666666666 rplD 0.9166666666666666 - 0.9166666666666666 - 0.9166666666666666 ko:K02926 0.8333333333333334 ko03010,map03010 0.9166666666666666 M00178 0.9166666666666666 - 0.9166666666666666 - 0.9166666666666666 br01610,ko00000,ko00001,ko00002,ko03011 0.9166666666666666 - 1.0 - 1.0 - 1.0 Ribosomal_L4 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_02256 0.08333333333333333 - - - - 0.9166666666666666 0.9166666666666666 0.9166666666666666 0.9166666666666666 Ribosome 0.9166666666666666 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 0.8333333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7954091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)NLDNISENTSSAESR MGYG000003694_00680;MGYG000001186_01647;MGYG000002517_00135;MGYG000003694_02093 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_00680 0.25 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14516171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)NMFALLGK MGYG000002040_00814;MGYG000003291_01409;MGYG000001300_02540;MGYG000003899_00328 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WHJX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002040_00814 0.25 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742072 0 484639 0 0 0 0 0 0 0 0 530353 0 0 0 0 59620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 69530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)NPEVQFC(Carbamidomethyl)HSTGTR MGYG000002794_01702 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp003487665|m__MGYG000002794 1.0 COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia,2N8Z1@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate-binding protein PnrA-like 1.0 - 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_01702 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07335:bmpA, bmpB, tmpC; basic membrane protein A and related proteins 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3648888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)QIEETTSDFDREK MGYG000000919_03652;MGYG000000202_00541;MGYG000002992_01078;MGYG000000038_02089;MGYG000003486_00745;MGYG000001607_00737;MGYG000001496_00484;MGYG000000278_02028;MGYG000000179_05119;MGYG000001615_01161;MGYG000000198_00464;MGYG000002445_00865;MGYG000000217_01904;MGYG000003783_01372;MGYG000001367_02937;MGYG000001688_01574;MGYG000001617_04641;MGYG000004087_02347;MGYG000000262_01443;MGYG000001193_01063;MGYG000002247_01828;MGYG000002279_00394 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,21YIV@1506553|Lachnoclostridium 0.4090909090909091 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.9545454545454546 MGYG000000919_03652 0.045454545454545456 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1495015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)QLEEAGAEVELK MGYG000000053_00901;MGYG000000044_01728;MGYG000000183_03084;MGYG000003202_00136;MGYG000004468_00169;MGYG000001562_01082;MGYG000002082_01855;MGYG000003701_03116;MGYG000003279_00958;MGYG000000825_01460;MGYG000004006_00426;MGYG000003282_01991;MGYG000004830_01657;MGYG000001546_01548;MGYG000004469_00969;MGYG000002867_00700;MGYG000001655_02927;MGYG000001608_02199;MGYG000002007_00362;MGYG000001489_05034;MGYG000000003_02516;MGYG000000138_00672;MGYG000002438_02328;MGYG000000117_01470;MGYG000002033_01014;MGYG000004573_00011;MGYG000003172_00544;MGYG000002203_00881;MGYG000000254_02576;MGYG000000074_01766;MGYG000000144_02611;MGYG000003498_00517;MGYG000004711_00303;MGYG000000222_01120;MGYG000001552_00977;MGYG000004658_01198;MGYG000002556_01325 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 0.43243243243243246 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 0.972972972972973 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000053_00901 0.02702702702702703 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1102722 0 1071526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)QYAVVLAVAK MGYG000000200_01752 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp003471165|m__MGYG000000200 1.0 COG3209@1|root,COG3209@2|Bacteria,1TRJ1@1239|Firmicutes,24AU6@186801|Clostridia,3WHF3@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 M 1.0 COG3209 Rhs family protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Big_2,Flg_new,Fn3_assoc,LRR_5,Lipase_3,N_methyl,Peptidase_M15_4,Transglut_core 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000200_01752 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3692564 0 0 0 0 3156864 0 0 0 0 2749352 0 0 0 5326412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1332889 0 0 0 0 0 0 0 0 0 1679658 0 0 0 5693129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2680250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428964 0 0 0 0 481445 0 0 0 1173532 0 0 0 0 0 0 +(Propionamide)RPEPYKGK MGYG000004558_00361;MGYG000002534_00407;MGYG000002494_02454;MGYG000000154_01823;MGYG000002148_03762;MGYG000000198_04902;MGYG000002445_01497;MGYG000000142_02052;MGYG000000136_02063;MGYG000000181_01077;MGYG000000205_02189;MGYG000002517_02858;MGYG000000280_01282;MGYG000000118_00219;MGYG000000235_04525;MGYG000000515_01674;MGYG000002835_00991;MGYG000000200_01098;MGYG000000249_01536;MGYG000004271_00031;MGYG000004740_00882;MGYG000001714_01313;MGYG000002141_01709;MGYG000000164_02749;MGYG000004869_03335;MGYG000000212_03062;MGYG000001617_01229;MGYG000002279_01057;MGYG000000184_01187;MGYG000000217_01269;MGYG000001637_00016;MGYG000000251_01816;MGYG000000312_01463;MGYG000000038_01591;MGYG000002670_00401;MGYG000000076_02823;MGYG000000242_01808;MGYG000000245_02653;MGYG000000271_01076;MGYG000002966_02560;MGYG000001496_03135;MGYG000002492_00390;MGYG000002366_00451;MGYG000000095_00559;MGYG000003821_00354;MGYG000000002_00867;MGYG000002415_02001;MGYG000000206_01049;MGYG000000179_04585;MGYG000000233_02358;MGYG000002477_00172;MGYG000000806_01297;MGYG000002502_01800;MGYG000002506_02946;MGYG000001970_02204;MGYG000002323_00401;MGYG000004519_01474;MGYG000002504_03949;MGYG000002836_03716;MGYG000004762_01319;MGYG000001615_01744;MGYG000001338_02792;MGYG000002286_01574;MGYG000001065_00455;MGYG000002202_01344;MGYG000001374_01181;MGYG000000255_01825;MGYG000000133_00060;MGYG000000216_02348 domain d__Bacteria 1.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,3XYVK@572511|Blautia 0.21739130434782608 186801|Clostridia 0.855072463768116 J 1.0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center 0.8695652173913043 rplF 1.0 - 0.855072463768116 - 1.0 ko:K02933 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004558_00361 0.014492753623188406 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02933:RP-L6, MRPL6, rplF; large subunit ribosomal protein L6 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573546 0 0 0 0 0 468626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)SLGEISDAVEK MGYG000000742_00316 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900541605|m__MGYG000000742 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H37I@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000742_00316 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16437751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)SLGEISDAVEKVSGR MGYG000000742_00316 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900541605|m__MGYG000000742 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H37I@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000742_00316 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1192713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)SVFDLSAEDFAK MGYG000000236_04341 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0149@1|root,COG2259@1|root,COG0149@2|Bacteria,COG2259@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia,4AVCD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 DoxX,MauE,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_04341 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 728927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)SVGADCVAHGSTGAGNDQVR MGYG000000074_01979 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0137@1|root,COG0137@2|Bacteria,4NE3R@976|Bacteroidetes,2FMRA@200643|Bacteroidia,22UZN@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Arginosuccinate synthase 1.0 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01979 1.0 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids|Fluid shear stress and atherosclerosis 1.0 K01940:argG, ASS1; argininosuccinate synthase [EC:6.3.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1409434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)TGSAAYNQK MGYG000001415_01222 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_01222 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)TSITIDGDNFNFYFEK MGYG000000198_05929 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,21ZAM@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_05929 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9494996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)TSNLSLDER MGYG000000074_00675 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1409@1|root,COG1409@2|Bacteria,4PNR4@976|Bacteroidetes,2FZJW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Putative binding domain, N-terminal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BACON 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00675 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2642387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)TVEALGLK MGYG000001310_00105;MGYG000000194_02264;MGYG000000038_01594;MGYG000002835_00994;MGYG000001496_03138;MGYG000000249_01533;MGYG000001456.1_01734;MGYG000000146_01033;MGYG000002772_00339;MGYG000002528_01857;MGYG000000159_01029;MGYG000003324_00563;MGYG000000164_02746;MGYG000000262_00164;MGYG000002290_02006;MGYG000002279_01054;MGYG000001315_01354 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1841@1|root,COG1841@2|Bacteria,1TU6C@1239|Firmicutes,2588K@186801|Clostridia,3WM76@541000|Ruminococcaceae 0.17647058823529413 186801|Clostridia 0.8823529411764706 J 1.0 Ribosomal protein L30p/L7e 0.7058823529411765 rpmD 1.0 - 0.8823529411764706 - 1.0 ko:K02907 0.8235294117647058 ko03010,map03010 0.8235294117647058 M00178,M00179 0.8235294117647058 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.8235294117647058 - 1.0 - 1.0 - 1.0 Ribosomal_L30 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_00105 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.8235294117647058 K02907:RP-L30, MRPL30, rpmD; large subunit ribosomal protein L30 0.8235294117647058 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1390955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)VADDIQAR MGYG000001658_01510;MGYG000002641_02426;MGYG000001300_01498;MGYG000000039_00844;MGYG000002224_01363;MGYG000002619_02323;MGYG000002098_00988;MGYG000000195_01879;MGYG000003166_00426;MGYG000000076_00689;MGYG000003291_00077;MGYG000000245_00548;MGYG000003899_02162;MGYG000002272_02091;MGYG000002545_02469;MGYG000002040_01179;MGYG000000201_01623;MGYG000000389_01654;MGYG000002517_01303;MGYG000002274_02019;MGYG000001255_01254;MGYG000002298_00512;MGYG000004733_01177 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 0.6956521739130435 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 0.8260869565217391 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 GH49 0.8695652173913043 MGYG000001658_01510 0.043478260869565216 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 658309 1460444 0 0 0 1377019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4011623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)VAGAATQSVADQEAIK MGYG000000054_01445 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides acidifaciens|m__MGYG000000054 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 MGYG000000054_01445 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1537390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)VAGVDAYIVDLNEPATASGR MGYG000002171_02932 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002493165|m__MGYG000002171 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_02932 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 535869 0 0 507341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 715712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)VAVVADDLAQESR MGYG000004642_00531;MGYG000004285_00367 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670 1.0 COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,36FZP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 2-hydroxyglutaryl-CoA dehydratase, D-component 1.0 - 1.0 - 1.0 1.3.7.8,4.2.1.54 1.0 ko:K04112,ko:K20627 1.0 ko00362,ko00640,ko00643,ko01100,ko01120,ko01220,map00362,map00640,map00643,map01100,map01120,map01220 1.0 M00541 1.0 R02451,R02963 1.0 RC00002,RC00818,RC01839 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HGD-D 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004642_00531 0.5 benzoyl-CoA reductase. | lactoyl-CoA dehydratase. - Inactive toward aromatic acids that are not CoA esters but will also catalyze the reaction: NH3 + acceptor + 2 ADP + 2 phosphate = hydroxylamine + reduced acceptor + 2 ATP + H2O.-!-In the presence of reduced acceptor, but in the absence of oxidizable substrate, the enzyme catalyzes the hydrolysis of ATP to ADP plus phosphate.-!-Formerly EC 1.3.99.15. | A bacterial enzyme that is involved in propanoate fermentation (also known as the acrylate pathway). 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized 2[4Fe-4S]- [ferredoxin] + 2 phosphate = 2 ATP + benzoyl-CoA + 2 H2O + reduced 2[4Fe- 4S]-[ferredoxin]. | (R)-lactoyl-CoA = acryloyl-CoA + H2O. 1.0 1.0 1.0 1.0 Benzoate degradation|Propanoate metabolism|Styrene degradation|Metabolic pathways|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04112:bcrC, badD; benzoyl-CoA reductase subunit C [EC:1.3.7.8]|K20627:lcdB; lactoyl-CoA dehydratase subunit beta [EC:4.2.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)VCVLEKEEDVC(Carbamidomethyl)C(Carbamidomethyl)GTSK MGYG000001379_01928;MGYG000000076_01007;MGYG000002279_02522;MGYG000000245_01076 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 0.75 186801|Clostridia 1.0 S 1.0 BFD-like [2Fe-2S] binding domain 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001379_01928 0.25 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1806167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)VSAIDFLK MGYG000002528_01043 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0493@1|root,COG0493@2|Bacteria,1TR18@1239|Firmicutes,24A8Q@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 'oxidoreductase 1.0 - 1.0 - 1.0 1.3.1.1 1.0 ko:K17722 1.0 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 1.0 M00046 1.0 R00977,R01414,R11026 1.0 RC00072,RC00123 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4_20,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01043 1.0 dihydrouracil dehydrogenase (NAD(+)). - The enzyme was originally discovered in the uracil-fermenting bacterium, Clostridium uracilicum, which utilizes uracil and thymine as nitrogen and carbon sources for growth.-!-Since then the enzyme was found in additional organisms including Alcaligenes eutrophus, Pseudomonas strains and Escherichia coli. (1) 5,6-dihydrouracil + NAD(+) = H(+) + NADH + uracil. (2) 5,6-dihydrothymine + NAD(+) = H(+) + NADH + thymine. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|beta-Alanine metabolism|Pantothenate and CoA biosynthesis|Metabolic pathways 1.0 K17722:preT; dihydropyrimidine dehydrogenase (NAD+) subunit PreT [EC:1.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1274356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)VSWYDNEMSYTSQLVR MGYG000004789_01485 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Streptococcaceae|g__Streptococcus|s__Streptococcus sp001556435|m__MGYG000004789 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli 1.0 91061|Bacilli 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 GO:0000166,GO:0002020,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0019899,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004789_01485 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)VTLSGPDGYIYDPDGITTK MGYG000000255_02227;MGYG000000233_02492 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,222GB@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_02227 0.5 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 351470 0 0 443311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326910 0 0 0 0 0 0 408212 0 0 0 0 0 0 0 379001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2959082 0 1627454 2258158 0 1116975 0 0 2303375 0 0 0 0 0 0 0 0 0 0 0 0 1835699 0 1456292 0 2803898 3086107 0 2736966 0 0 2010633 1656439 3455961 2723624 2025178 2322934 1388963 6725857 4764455 0 5790083 0 5644337 0 0 6036079 0 3755066 0 0 0 0 0 0 0 0 5605677 0 6511032 0 4482835 0 4087266 5887239 0 0 0 0 0 5354318 6378595 5652272 6668848 0 3915985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)VYPAVQGQALK MGYG000000243_01886;MGYG000002171_01694 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01886 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 7791023 0 0 3451940 0 0 0 0 3577103 0 0 0 4245609 4637689 0 0 0 0 0 0 0 4942424 0 0 0 0 0 4022982 6589525 0 0 0 0 0 3946300 9311451 0 0 0 0 0 0 0 0 0 0 148896 0 0 0 0 0 0 0 0 0 0 268109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)YDVLEDGAFK MGYG000001602_00394 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia|s__Blautia sp900547685|m__MGYG000001602 1.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,3Y02G@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit 1.0 rpsH 1.0 - 1.0 - 1.0 ko:K02994 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001602_00394 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02994:RP-S8, MRPS8, rpsH; small subunit ribosomal protein S8 1.0 none 1.0 0 0 0 0 0 273922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 679771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2072337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)YGIPHISTGDIFR MGYG000000194_02261;MGYG000000479_01390;MGYG000001247_00924;MGYG000000077_00875;MGYG000004733_00989;MGYG000000216_02342;MGYG000000398_00972;MGYG000002989_00878;MGYG000001785_00490;MGYG000001577_00628;MGYG000002966_02554;MGYG000003012_01979;MGYG000001619_00813;MGYG000000135_01184;MGYG000000252_01798;MGYG000002298_00349;MGYG000001543_00396;MGYG000004697_01278;MGYG000002835_00997;MGYG000000002_00861;MGYG000003335_01412;MGYG000003821_00360;MGYG000000205_02183;MGYG000000171_01884;MGYG000004879_01576;MGYG000000274_01716;MGYG000000233_02364;MGYG000000206_01055;MGYG000001065_00449;MGYG000000133_00066;MGYG000000909_01226;MGYG000001315_01358;MGYG000000212_03068;MGYG000001199_01747;MGYG000001777_00253;MGYG000001793_01093;MGYG000000806_01303;MGYG000000690_01580;MGYG000000404_01617 domain d__Bacteria 1.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3XZAB@572511|Blautia 0.358974358974359 186801|Clostridia 0.9487179487179487 F 0.9743589743589743 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism 0.9743589743589743 adk 0.9743589743589743 - 1.0 2.7.4.3 0.9743589743589743 ko:K00939 0.9743589743589743 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 0.9743589743589743 M00049 0.9743589743589743 R00127,R01547,R11319 0.9743589743589743 RC00002 0.9743589743589743 ko00000,ko00001,ko00002,ko01000,ko04147 0.9743589743589743 - 1.0 - 1.0 iHN637.CLJU_RS20110 0.9230769230769231 ADK,ADK_lid 0.9743589743589743 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000194_02261 0.02564102564102564 adenylate kinase. myokinase. Inorganic triphosphate can also act as donor. AMP + ATP = 2 ADP. 0.9743589743589743 0.9743589743589743 0.9743589743589743 0.9743589743589743 Purine metabolism|Thiamine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 0.9743589743589743 K00939:adk, AK; adenylate kinase [EC:2.7.4.3] 0.9743589743589743 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)YIIAPEGIK MGYG000003683_01135;MGYG000000171_01902;MGYG000002395_00353;MGYG000000142_02064;MGYG000000200_01110;MGYG000002835_00979;MGYG000000002_00879;MGYG000003702_00697;MGYG000003452_00885;MGYG000000164_02761;MGYG000002459_00382;MGYG000001490_00323;MGYG000000756_00965;MGYG000000184_01175;MGYG000000133_00048;MGYG000001338_02804;MGYG000000127_02546 domain d__Bacteria 1.0 COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,4CZ5U@85004|Bifidobacteriales 0.35294117647058826 186801|Clostridia 0.6470588235294118 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 0.6470588235294118 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01135 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3165272 0 0 0 0 0 0 0 0 0 0 0 4862985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 887325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionamide)YSVVC(Carbamidomethyl)GSFGVK MGYG000003681_01674 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG3087@1|root,COG3087@2|Bacteria,4NU0A@976|Bacteroidetes,2FPJ1@200643|Bacteroidia,4AKB9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 D 1.0 Sporulation and cell division repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SPOR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_01674 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1842646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1907062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl)ADGGSKDFATYDDDGAVYVQR MGYG000002445_02384 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp003024715|m__MGYG000002445 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002445_02384 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3118726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl)AEDAAKTIGVGLQSFC(Carbamidomethyl)IPGSVADDR MGYG000000045_01847 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 2C4R5@1|root,2Z7JK@2|Bacteria 1.0 2|Bacteria 1.0 S 1.0 Psort location Cytoplasmic, score 1.0 BT0173 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000045_01847 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl)ALVANGVFAVSEGANMPSTPEAIR MGYG000001789_00079;MGYG000003693_00557 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AKTV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001789_00079 0.5 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 1.0 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 286742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1997307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl)ANDQPFIMPVEDVFSITGR MGYG000003324_00542 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Anaerovoracaceae|g__VUNA01|s__|m__MGYG000003324 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WCCR@538999|Clostridiales incertae sedis 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003324_00542 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl)FDVLATDVLSSIDTALK MGYG000002494_03500 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1344@1|root,COG1344@2|Bacteria,1MV1N@1224|Proteobacteria,1RN0Y@1236|Gammaproteobacteria,3X1YU@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 fliC 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03500 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl)GQNADLFIAGPAFNAGR MGYG000000146_02851 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea|s__Dorea formicigenerans|m__MGYG000000146 1.0 COG1978@1|root,COG1978@2|Bacteria,1TPAB@1239|Firmicutes,2487X@186801|Clostridia,27UY7@189330|Dorea 1.0 186801|Clostridia 1.0 S 1.0 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) 1.0 grdB 1.0 - 1.0 1.21.4.2 1.0 ko:K10672 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 GRDB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000146_02851 1.0 glycine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. 1.0 1.0 1.0 1.0 - 1.0 K10672:grdB; glycine reductase complex component B subunit gamma [EC:1.21.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2298119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2679575 0 0 0 0 3742324 0 0 0 0 0 0 0 0 0 0 0 0 0 2129681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl)LSAAEVETLLR MGYG000001415_00893 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,22UVQ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_00893 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 232779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243625 0 0 0 0 0 0 0 0 0 0 268339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl)LVALIEASDAMVK MGYG000002494_04005;MGYG000002477_02044 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG4576@1|root,COG4577@1|root,COG4576@2|Bacteria,COG4577@2|Bacteria,1RIK4@1224|Proteobacteria,1S6GW@1236|Gammaproteobacteria,3ZNAY@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 CQ 1.0 Ethanolamine utilisation protein EutN/carboxysome 1.0 eutN 1.0 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 1.0 - 1.0 ko:K04028 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC,EutN_CcmL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04005 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04028:eutN; ethanolamine utilization protein EutN 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl)LVAMNMMEGTLVQIR MGYG000002494_02689 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily 1.0 frdA 1.0 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.0 1.3.5.4 1.0 ko:K00244 1.0 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 1.0 M00009,M00011,M00150,M00173 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECIAI39_1322.ECIAI39_4621,iEcSMS35_1347.EcSMS35_4625,iPC815.YPO0360 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02689 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Two-component system 1.0 K00244:frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl)MLDAAGILTAR MGYG000002082_00584;MGYG000003279_00708;MGYG000000074_01177 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,22U5P@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002082_00584 0.3333333333333333 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 2186542 3386945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2703759 0 3194813 0 0 4067573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3131196 3119250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2995907 0 3582499 0 0 4712208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4496323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1891985 1773927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2097986 0 1207679 0 0 3075643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3343392 4060779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2965357 0 3408806 0 0 3978012 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl)PEIMLVGATAIGR MGYG000000312_02427;MGYG000000164_00688;MGYG000002492_00661;MGYG000002517_00544;MGYG000000245_02023;MGYG000002528_02669 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8333333333333334 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000312_02427 0.16666666666666666 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1157395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 504191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl)SEGYQDFLNGEVR MGYG000001310_00851 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001310_00851 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 868902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl_13C(3))AGFAASQDLVGNTWTPEHTNAK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01126 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 526622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053620 0 0 0 1593827 0 0 0 711753 701878 0 0 0 882781 0 0 308889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343575 0 0 0 0 +(Propionyl_13C(3))AGFAASQDLVGNTWTPEHTNAKFPK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01126 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl_13C(3))AIETGVPK MGYG000002171_02052;MGYG000000243_02184;MGYG000002478_00340 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,4AMCS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Psort location Cytoplasmic, score 8.96 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_02052 0.3333333333333333 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1865603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl_13C(3))ANVELVGYEK MGYG000001065_00269 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp900538485|m__MGYG000001065 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,2235C@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 CQ 1.0 BMC domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001065_00269 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl_13C(3))AVDYIMDKLAEK MGYG000002528_02668 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02668 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl_13C(3))DVVANADGQVIIGEVNQDATAQNIQQR MGYG000000200_00369 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp003471165|m__MGYG000000200 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000200_00369 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 890754 0 0 0 0 858567 0 0 0 0 854555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 678125 0 0 0 0 0 0 0 0 0 1142555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 441163 0 0 0 0 0 0 0 0 0 320450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl_13C(3))DVVANADGQVVIGEVNQDATAQNIQQR MGYG000004733_00834;MGYG000000212_00952 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_00834 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 548537 0 355644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propionyl_13C(3))LIDEFEKLEGR MGYG000000742_00316 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900541605|m__MGYG000000742 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TQAD@1239|Firmicutes,4H37I@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000742_00316 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3934566 0 0 0 0 6356086 0 0 0 0 5614239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)AAFEEAEHAAK MGYG000003509_00509;MGYG000000177_00118;MGYG000002026_00456;MGYG000003891_00390;MGYG000004769_01404;MGYG000000198_03730;MGYG000000172_04155;MGYG000004087_01663;MGYG000001434_00926;MGYG000000198_03710;MGYG000004087_01662;MGYG000001564_01103;MGYG000001311_01511;MGYG000001493_02801;MGYG000001493_02800;MGYG000003422_00075;MGYG000004713_00792 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,21YU6@1506553|Lachnoclostridium 0.5294117647058824 186801|Clostridia 0.8823529411764706 C 1.0 Rubrerythrin 0.6470588235294118 rbr3A 0.9411764705882353 - 0.9411764705882353 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.8823529411764706 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003509_00509 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2841248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)ADADIASDDAIKK MGYG000000212_00409 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG1879@1|root,COG1879@2|Bacteria,1TRBC@1239|Firmicutes,24DQX@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_00409 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)ADAPQFNVGDTVK MGYG000004735_00305 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 - 1.0 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00305 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02884:RP-L19, MRPL19, rplS; large subunit ribosomal protein L19 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7100136 0 0 0 0 0 0 0 +(Propyl)AFADLDEDQQK MGYG000002218_01634 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides sp000436495|m__MGYG000002218 1.0 COG0848@1|root,COG0848@2|Bacteria,4NHYQ@976|Bacteroidetes,2FMZ4@200643|Bacteroidia,22Y6V@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Biopolymer transporter ExbD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ExbD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002218_01634 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1270489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)AGFMGIPVPK MGYG000000404_01797;MGYG000000312_02425;MGYG000001814_02502 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,27K1G@186928|unclassified Lachnospiraceae 0.6666666666666666 186801|Clostridia 1.0 I 0.6666666666666666 Acyl-CoA dehydrogenase, C-terminal domain 0.6666666666666666 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000404_01797 0.3333333333333333 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 9890275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)AIDPAAMAK MGYG000001310_00280;MGYG000002772_01916;MGYG000000249_01751 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 0.6666666666666666 adh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_00280 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 368333 163015 507096 349524 167575 514457 202036 190364 0 0 495300 0 0 220073 136364 507149 0 0 0 0 502878 549666 0 335236 723926 310631 490029 0 0 1062235 457675 459877 345868 742347 551287 254605 225362 281960 0 9524823 6366613 13631395 6444511 4651941 10782836 14840271 0 0 6615874 0 0 10882815 10109415 4787132 0 0 0 0 7211264 4374699 0 6313904 10462634 10596956 12788845 0 0 6856932 6187680 8596647 9496154 22777977 13627189 13534279 10347324 0 300177 665867 192847 505552 213534 171179 222273 366636 0 0 138401 0 0 165748 204978 278619 0 0 0 0 379764 363092 0 452416 257603 229014 388445 0 0 260994 351164 431082 195823 585118 202106 164837 0 272190 251236 0 353916 254489 616668 460585 420557 447012 0 0 623816 0 0 481391 811868 796131 0 0 0 0 798031 1122438 0 353041 795544 566613 809448 0 0 953873 802758 847309 797525 372720 915839 262522 331842 428022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1321727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1026160 0 +(Propyl)ALISIAHPDFR MGYG000000077_02473 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum soehngenii|m__MGYG000000077 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,25VHE@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02473 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 805758 548644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518904 465832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)ALTTKHER MGYG000000236_00435 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG1883@1|root,COG1883@2|Bacteria,4NH3V@976|Bacteroidetes,2FMSY@200643|Bacteroidia,4ANA7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 sodium ion-translocating decarboxylase, beta subunit 1.0 oadB 1.0 - 1.0 4.1.1.3 1.0 ko:K01572 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 OAD_beta 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_00435 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01572:- 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)ASYGETGLDESAGR MGYG000002721_02202 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-873|s__CAG-873 sp009775195|m__MGYG000002721 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002721_02202 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3175042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)ATVLGHIQR MGYG000002366_04608;MGYG000003394_01036;MGYG000001423_01186;MGYG000000337_02244;MGYG000002534_04706;MGYG000002504_03852;MGYG000002323_04064;MGYG000000093_04937;MGYG000002506_03612;MGYG000002494_01934 domain d__Bacteria 1.0 COG0205@1|root,COG0205@2|Bacteria,1MVN3@1224|Proteobacteria,1RMVY@1236|Gammaproteobacteria,3XNE3@561|Escherichia 0.7 1236|Gammaproteobacteria 0.8 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 0.9 pfkA 1.0 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003872,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005945,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019200,GO:0019318,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035639,GO:0036094,GO:0042802,GO:0042866,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0061615,GO:0061695,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494,GO:1990234 0.8 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 iNRG857_1313.NRG857_19550 0.8 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002366_04608 0.1 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1671804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)AVALEDEKIK MGYG000001496_02714 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Extibacter|s__Extibacter sp001185345|m__MGYG000001496 1.0 28HF7@1|root,2Z7RC@2|Bacteria,1TQET@1239|Firmicutes,249YW@186801|Clostridia,27V4K@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 Glycine/sarcosine/betaine reductase component B subunits 1.0 grdE 1.0 - 1.0 1.21.4.2 1.0 ko:K10671 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001496_02714 1.0 glycine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. 1.0 1.0 1.0 1.0 - 1.0 K10671:grdE; glycine reductase complex component B subunit alpha and beta [EC:1.21.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1742567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)AVPIQLPIGK MGYG000002926_00231 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,2N72W@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000002926_00231 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 728274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210525 0 0 0 0 0 0 0 0 0 0 114325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)AVVFINC(Carbamidomethyl)K MGYG000003510_00582 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__UBA6857|s__|m__MGYG000003510 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000003510_00582 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2529601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176096 0 0 0 0 0 0 0 0 +(Propyl)EADPELQIVAFKR MGYG000004797_01413;MGYG000002478_01739 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01413 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)GALLVGPPGTGK MGYG000001787_01446;MGYG000002478_02017;MGYG000000251_01096;MGYG000001675_00396;MGYG000004105_01889;MGYG000004006_00226;MGYG000002966_02777;MGYG000000364_01789;MGYG000004879_00637;MGYG000001310_01000;MGYG000000201_02976;MGYG000002171_01780;MGYG000002298_03713;MGYG000002528_01333;MGYG000002638_00844;MGYG000000142_01577;MGYG000001193_00690;MGYG000003149_00769;MGYG000001315_00392;MGYG000002540_02250;MGYG000001423_00451;MGYG000004414_00685;MGYG000001461_01641;MGYG000002247_02233;MGYG000001630_01353;MGYG000000121_03763;MGYG000000171_02296;MGYG000001338_00422;MGYG000001655_01521;MGYG000000216_00467;MGYG000002275_00331;MGYG000003486_02088;MGYG000004757_01506;MGYG000000484_01836;MGYG000003565_00613;MGYG000000042_00712;MGYG000002946_03966;MGYG000004899_01671;MGYG000000325_02475;MGYG000000255_02652;MGYG000000271_03460;MGYG000001789_00355;MGYG000000387_01574;MGYG000000223_03489;MGYG000000127_05497;MGYG000001804_00967;MGYG000002963_00296;MGYG000000201_02153;MGYG000000251_00277;MGYG000004703_01701;MGYG000002438_02722;MGYG000002082_00215;MGYG000004317_02215;MGYG000000154_01586;MGYG000004733_02060;MGYG000000198_00286;MGYG000000781_00218;MGYG000001617_00913;MGYG000004740_00938;MGYG000001567_00555;MGYG000002492_00620;MGYG000004464_01963;MGYG000002517_00481;MGYG000004891_02849;MGYG000003202_01226;MGYG000002772_00708;MGYG000003366_01210;MGYG000003367_00619;MGYG000000105_02204;MGYG000000138_02290;MGYG000001338_01442;MGYG000001606_02454;MGYG000002052_00044;MGYG000002875_00453;MGYG000000172_03039;MGYG000001503_01865;MGYG000002133_01352;MGYG000004885_00121;MGYG000000249_00927;MGYG000002989_01596;MGYG000000142_02465;MGYG000001783_02519;MGYG000000243_02615;MGYG000003984_01746;MGYG000001814_01099;MGYG000002614_00650;MGYG000003353_01906;MGYG000000153_02386;MGYG000000031_02902;MGYG000003821_01844;MGYG000001602_02233;MGYG000002279_00289;MGYG000000262_01668;MGYG000001378_03057;MGYG000000171_00202;MGYG000003460_01946;MGYG000002298_02917;MGYG000001370_01381;MGYG000003493_00456;MGYG000003546_00869;MGYG000003362_02047;MGYG000003702_02477;MGYG000000200_03319;MGYG000004271_00167;MGYG000000255_01996;MGYG000000205_00988;MGYG000000073_00731;MGYG000001623_03260;MGYG000003922_00970;MGYG000002042_00092;MGYG000001364_01334;MGYG000002033_00064;MGYG000000301_00550;MGYG000001489_00269;MGYG000003351_03543;MGYG000003215_00517;MGYG000004830_00142;MGYG000000245_01966;MGYG000002905_00935;MGYG000002218_00112;MGYG000000164_02134;MGYG000002155_00457;MGYG000000133_02963;MGYG000001570_01070 domain d__Bacteria 1.0 COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,2FNEA@200643|Bacteroidia,4AKUK@815|Bacteroidaceae 0.1532258064516129 186801|Clostridia 0.6129032258064516 O 1.0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins 1.0 ftsH 0.9919354838709677 - 1.0 - 1.0 ko:K03798 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000,ko01002,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,FtsH_ext,Peptidase_M41 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001787_01446 0.008064516129032258 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03798:ftsH, hflB; cell division protease FtsH [EC:3.4.24.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)GAVIPELDGK MGYG000004729_00235 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Anaerovoracaceae|g__Eubacterium_T|s__|m__MGYG000004729 1.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,42N9Q@68525|delta/epsilon subdivisions,2WIK1@28221|Deltaproteobacteria,43S9H@69541|Desulfuromonadales 1.0 28221|Deltaproteobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gapA 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004729_00235 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)GFIENVLR MGYG000000215_01440 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella stercorea|m__MGYG000000215 1.0 COG0329@1|root,COG0329@2|Bacteria,4NFP9@976|Bacteroidetes,2FMFC@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) 1.0 dapA 1.0 - 1.0 4.3.3.7 1.0 ko:K01714 1.0 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 1.0 M00016,M00525,M00526,M00527 1.0 R10147 1.0 RC03062,RC03063 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHDPS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000215_01440 1.0 4-hydroxy-tetrahydrodipicolinate synthase. dihydrodipicolinate synthetase. The reaction can be divided into three consecutive steps: Schiff base formation with pyruvate, the addition of L-aspartate-semialdehyde, and finally transimination leading to cyclization with simultaneous dissociation of the product.-!-The product of the enzyme was initially thought to be (S)-2,3- dihydrodipicolinate, and the enzyme was classified accordingly as EC 4.2.1.52.-!-Later studies of the enzyme from the bacterium Escherichia coli have suggested that the actual product of the enzyme is (2S,4S)-4-hydroxy- 2,3,4,5-tetrahydrodipicolinate, and thus the enzyme has been reclassified as 4-hydroxy-tetrahydrodipicolinate synthase.-!-However, the identity of the product is still controversial, as more recently it has been suggested that it may be (S)-2,3- dihydrodipicolinate after all.-!-Formerly EC 4.2.1.52. L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5- tetrahydrodipicolinate + H(+) + H2O. 1.0 1.0 1.0 1.0 Monobactam biosynthesis|Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01714:dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4269351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)GTDIKLDEEAK MGYG000000198_05418 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,21YP5@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane 1.0 secA 1.0 - 1.0 - 1.0 ko:K03070 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 1.0 - 1.0 - 1.0 Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW 1.0 - 1.0 - 1.0 GT41 1.0 - 1.0 MGYG000000198_05418 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03070:secA; preprotein translocase subunit SecA [EC:7.4.2.8] 1.0 none 1.0 0 0 0 2074563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)LGTGDDQIVSAGFDAGSVIK MGYG000002772_00505 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__|m__MGYG000002772 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,36GVP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002772_00505 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7810874 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8757830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)NAKYPTISQENGVQGK MGYG000000243_02206 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0810@1|root,COG0810@2|Bacteria,4NMG7@976|Bacteroidetes,2FPKW@200643|Bacteroidia,4AKHT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins 1.0 - 1.0 - 1.0 - 1.0 ko:K03832 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 2.C.1.1 1.0 - 1.0 - 1.0 TonB_C,VIT,VWA_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02206 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03832:tonB; periplasmic protein TonB 1.0 none 1.0 0 0 0 0 0 519971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726763 0 0 0 0 0 0 0 0 0 0 0 0 0 1026979 0 0 0 0 0 0 0 401962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177879 0 0 +(Propyl)NAQESALK MGYG000000196_04532 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,4NEQV@976|Bacteroidetes,2FMXG@200643|Bacteroidia,4AMK8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG5016 Pyruvate oxaloacetate carboxyltransferase 1.0 cfiA 1.0 - 1.0 6.4.1.1 1.0 ko:K01960 1.0 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 1.0 M00173,M00620 1.0 R00344 1.0 RC00040,RC00367 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl,HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04532 1.0 pyruvate carboxylase. pyruvic carboxylase. The animal enzyme requires acetyl-CoA. ATP + hydrogencarbonate + pyruvate = ADP + H(+) + oxaloacetate + phosphate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01960:pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5070408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)QALENIK MGYG000000953_00047;MGYG000002485_00024 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0049@1|root,COG0049@2|Bacteria,3790N@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000953_00047 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2650985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)QGILTVSLK MGYG000003482_02091 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Selenomonas_C|s__Selenomonas_C bovis|m__MGYG000003482 1.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4H4AT@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit 1.0 rpsH 1.0 - 1.0 - 1.0 ko:K02994 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003482_02091 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02994:RP-S8, MRPS8, rpsH; small subunit ribosomal protein S8 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2907225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)SGMTPKFINGLR MGYG000000127_03225 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Catenibacillus|s__Catenibacillus sp902363555|m__MGYG000000127 1.0 COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the acetylglutamate kinase family. ArgB subfamily 1.0 argB 1.0 - 1.0 2.7.2.8 1.0 ko:K00930 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028 1.0 R02649 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AA_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000127_03225 1.0 acetylglutamate kinase. - - ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00930:argB; acetylglutamate kinase [EC:2.7.2.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 919258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)TATADQAEEVC(Carbamidomethyl)AAIR MGYG000003921_00579;MGYG000003937_01848;MGYG000001157_01821 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_00579 0.3333333333333333 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 830697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459347 0 0 0 0 394352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 445143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)TGIQITKAANDDLLNSFWLLDSEKGEAR MGYG000002506_02099 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG3445@1|root,COG3445@2|Bacteria,1RDRB@1224|Proteobacteria,1S45G@1236|Gammaproteobacteria,3XPJB@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Acts as a radical domain for damaged PFL and possibly other radical proteins 1.0 grcA 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.0 - 1.0 ko:K06866 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 iSF_1195.SF2641,iSFxv_1172.SFxv_2898,iS_1188.S2814 1.0 Gly_radical 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02099 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06866:grcA; autonomous glycyl radical cofactor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl)VGATAADIGAIGITNQR MGYG000002517_00259 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00259 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 1372913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 957237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1865310 +(Propyl_2H(6))EVLGGTVSC(Carbamidomethyl)SR MGYG000000271_02100;MGYG000000389_02147;MGYG000002517_00544;MGYG000000154_01280;MGYG000004697_01805;MGYG000000076_01277;MGYG000003486_02520 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.7142857142857143 etfA 1.0 - 0.8571428571428571 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02100 0.14285714285714285 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23734632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Propyl_2H(6))GFEMEYQVDPLR MGYG000004479_02858 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola mediterraneensis|m__MGYG000004479 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,4AKE4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004479_02858 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 738729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466551 0 0 0 0 576931 0 0 475592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 499474 0 0 0 0 945141 0 0 5141385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4470009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 861755 0 0 0 0 0 +(Propyl_2H(6))QMFGAEGFEIVAINDLTSPK MGYG000000301_01012;MGYG000000212_01474;MGYG000000171_00850;MGYG000000002_02120;MGYG000002212_00259;MGYG000002966_00075;MGYG000001338_02547;MGYG000000133_02283;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000001315_01699;MGYG000003702_00925;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_01012 0.0625 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(PyMIC)IEDAKAEIAR MGYG000000271_02507;MGYG000004271_00779 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9,2.7.9.2 1.0 ko:K01007,ko:K08483 1.0 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060 1.0 M00173,M00374 1.0 R00199 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02507 0.5 phosphoenolpyruvate--protein phosphotransferase. | pyruvate, water dikinase. sugar--PEP phosphotransferase enzyme I. | pyruvate,water dikinase. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. | ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Phosphotransferase system (PTS) 1.0 K01007:pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2]|K08483:ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(PyMIC)MLLDAMENPEKYPQLTIR MGYG000002506_00229 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1882@1|root,COG1882@2|Bacteria,1MWBF@1224|Proteobacteria,1RM96@1236|Gammaproteobacteria,3XMX2@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 formate C-acetyltransferase activity 1.0 pflB 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECH74115_1262.ECH74115_1064,iECIAI39_1322.ECIAI39_2245,iECSP_1301.ECSP_1007,iECs_1301.ECs0986,iEcSMS35_1347.EcSMS35_2218,iG2583_1286.G2583_1138,iSDY_1059.SDY_2358,iZ_1308.Z1248 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00229 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyridylacetyl[AnyN-term](Phenylisocyanate)TLDSYIPEPER MGYG000001485_02164 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Pseudomonadales|f__Pseudomonadaceae|g__Pseudomonas_E|s__Pseudomonas_E massiliensis|m__MGYG000001485 1.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,1YM7S@136843|Pseudomonas fluorescens group 1.0 1236|Gammaproteobacteria 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001485_02164 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1783163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyridylacetyl[AnyN-term](Phenylisocyanate)TVIPEDVR MGYG000000243_02364 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,4AKHK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000243_02364 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2028623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyridylacetyl[AnyN-term](Phenylisocyanate)VAAALEEGK MGYG000000484_01539 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A sp000431815|m__MGYG000000484 1.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,4BWIF@830|Butyrivibrio 1.0 186801|Clostridia 1.0 EH 1.0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 1.0 pdxB 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C,ACT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000484_01539 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3768331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyridylacetyl[AnyN-term](Phenylisocyanate)VSIVDLR MGYG000000142_01784;MGYG000000077_01492;MGYG000000262_00348;MGYG000000184_01361;MGYG000001642_01325 domain d__Bacteria 1.0 COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,25WBX@186806|Eubacteriaceae 0.4 186801|Clostridia 0.8 L 0.4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA 0.4 priA 0.4 - 1.0 - 1.0 ko:K04066 0.4 - 0.6 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03400 0.4 - 1.0 - 1.0 - 1.0 DEAD,Helicase_C,ResIII 0.4 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01784 0.2 - - - - 1.0 1.0 1.0 1.0 - 0.6 K04066:priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4] 0.4 none 1.0 0 1207862 0 0 0 0 0 0 0 0 0 0 588640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyridylacetyl[AnyN-term](Phenylisocyanate)VSLVDLR MGYG000000262_00348 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,25WBX@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 csoS1C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_00348 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 586973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyridylacetyl[AnyN-term](Phenylisocyanate)VVVTMGPPPAEGMLR MGYG000002040_01718;MGYG000003899_01133;MGYG000000084_00626;MGYG000001300_00292;MGYG000003166_01337;MGYG000004732_01391;MGYG000004866_01547;MGYG000003937_01088;MGYG000002274_00048 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WH8V@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002040_01718 0.1111111111111111 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit|K22431:carD; caffeyl-CoA reductase-Etf complex subunit CarD [EC:1.3.1.108] 1.0 none 1.0 0 4396017 0 0 0 0 0 0 5761775 0 0 0 2554834 4140889 0 0 0 0 3706117 0 4416021 0 0 0 0 0 5605245 0 0 0 0 0 0 5173204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1749743 0 0 0 0 2263383 0 0 0 0 0 0 2108659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516166 0 0 0 0 0 0 0 0 0 0 0 573089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 730985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CADAVKEYGIK MGYG000002515_03180;MGYG000002323_00409;MGYG000002506_02938;MGYG000002477_00164 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,1S3Q2@1236|Gammaproteobacteria,3WY9K@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_03180 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 1.0 none 1.0 0 0 890125 0 0 1200961 0 0 0 1008005 0 0 0 859081 0 0 0 0 0 0 0 1092931 0 1427241 0 0 503228 0 0 1006585 0 0 721700 860088 0 0 0 1041384 0 0 1172596 0 0 1913860 0 0 0 1548050 0 0 0 837495 0 0 0 0 0 0 0 2156432 0 1534347 0 0 939492 0 0 1036824 0 0 1359804 828931 0 0 0 1047142 0 0 1257958 0 0 1597167 0 0 0 932651 0 0 0 1017181 0 0 0 0 0 0 0 1710205 0 1220317 0 0 922461 0 0 775965 0 0 966788 944233 0 0 0 746253 0 0 1117479 0 0 1695155 0 0 0 1285702 0 0 0 693863 0 0 0 0 0 0 0 1148397 0 712022 0 0 982278 0 0 1169870 0 0 1177034 1800907 0 0 0 393795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257076 0 0 435340 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CADLHEFNPMMGHR MGYG000000198_00250 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,21XUV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000198_00250 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 778350 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 979359 0 0 0 0 0 773950 0 0 0 0 0 0 0 0 0 660112 545702 0 247541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280274 0 0 0 0 0 376826 0 0 0 0 0 0 0 0 0 316894 302108 0 948782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 671808 0 0 0 0 0 708153 0 0 0 0 0 0 0 0 0 534937 709409 0 215539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293111 0 0 0 0 0 96855 0 0 0 0 0 0 0 0 0 323977 290495 0 +(Pyro-carbamidomethyl)CADYVLKDNPDVIR MGYG000000271_02809;MGYG000004271_01538 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02809 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CAELHEFNPMMGHR MGYG000000179_00100;MGYG000001646_00500;MGYG000002139_00077 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,21XUV@1506553|Lachnoclostridium 0.3333333333333333 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.6666666666666666 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000179_00100 0.3333333333333333 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 227142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423945 0 0 0 0 0 0 0 0 0 0 0 0 264363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242244 0 0 0 0 0 0 0 0 0 0 0 0 2151822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3503319 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CAEYALSR MGYG000002619_01801;MGYG000001300_02848;MGYG000002641_01266 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0152@1|root,COG0152@2|Bacteria,1VTBC@1239|Firmicutes,24ZTC@186801|Clostridia,3WH16@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 1.0 F 1.0 Belongs to the SAICAR synthetase family 0.6666666666666666 purC 1.0 - 1.0 6.3.2.6 1.0 ko:K01923 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04591 1.0 RC00064,RC00162 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 SAICAR_synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002619_01801 0.3333333333333333 phosphoribosylaminoimidazolesuccinocarboxamide synthase. SAICAR synthetase. Forms part of the purine biosynthesis pathway. 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate + ADP + 2 H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01923:purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110289 0 0 0 0 0 0 0 321655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CAHANEILQR MGYG000001345_03240;MGYG000000196_03771 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia,4AKWQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 1.0 rprY 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Response_reg,Trans_reg_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_03240 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 589501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 669278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CAQVAQC(Carbamidomethyl)YK MGYG000000089_02197 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000089_02197 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2415468 0 0 0 0 2353698 0 0 0 0 3288487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CATSDKASAELK MGYG000002517_00959;MGYG000000389_00578 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002517_00959 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 208027 716691 457769 0 0 0 0 0 0 0 733923 0 0 819890 863934 0 0 0 680688 0 0 0 0 449788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182102 311384 0 0 0 0 0 0 0 0 0 0 226189 0 0 0 0 473659 0 0 0 0 512248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2267052 5715399 5940644 0 0 0 0 0 0 0 3609395 0 0 4265264 2571463 0 0 0 6010436 0 0 0 0 3922222 1702437 0 0 0 0 0 0 0 0 0 0 0 0 0 1955227 1539437 2457050 0 0 0 0 0 0 0 3100822 0 0 1931364 2050078 0 0 0 3089655 0 0 0 0 1452789 2726326 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CAYGWAKED MGYG000000164_01754 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_01754 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 1511690 0 0 0 0 746515 0 0 0 0 0 0 0 0 0 0 0 0 0 1935690 0 964599 0 367188 0 2036310 0 0 0 0 0 0 0 0 1627444 0 1318897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CAYTPDKK MGYG000002517_01658 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01658 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 781303 0 491130 0 900708 774902 348032 0 605937 1053715 363942 722952 0 0 861541 0 755585 0 1091382 731667 922198 760160 0 725282 772767 567631 817005 0 0 726654 304999 0 412562 770395 0 0 759170 456423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321070 0 0 0 0 0 0 0 276872 430103 0 0 0 0 475480 0 162719 0 501634 434786 0 140473 0 0 395820 634468 511681 0 0 392251 0 0 0 0 0 0 624165 0 4564639 0 896627 0 3087801 1780552 2602693 0 6622574 2716157 1866450 2929694 0 0 6515226 0 4296570 0 4825870 4717498 2610039 389185 0 383917 6595199 5547317 5469917 0 0 4455275 1334935 0 1126005 3195282 0 0 5946141 934215 2511973 0 3693706 0 2288361 3268517 3169371 0 2824972 4336355 3981083 3444730 0 0 3123655 0 3594784 0 3544245 2088569 3666097 3187763 0 3286451 5226864 4247083 3680047 0 0 2249602 2710143 0 4040405 3537036 0 0 5813499 4011141 +(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHAAIRPF MGYG000001920_00369 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900546355|m__MGYG000001920 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001920_00369 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1162620 0 0 0 0 802280 0 0 0 0 1532841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHAAIRPV MGYG000002298_00647;MGYG000001315_01946;MGYG000000031_03215 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3XZ4K@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002298_00647 0.3333333333333333 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHAAIRPVALTEEELAKAPEGLK MGYG000001315_01946 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,27VFG@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001315_01946 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHASIRPF MGYG000001345_00428;MGYG000000196_04414;MGYG000002033_00365;MGYG000000013_01171;MGYG000002549_02787;MGYG000000138_01901;MGYG000000029_01835;MGYG000002540_01631;MGYG000002455_00144;MGYG000001780_02881;MGYG000003681_00938;MGYG000001346_02526;MGYG000003363_02878;MGYG000001337_03683;MGYG000001313_00862;MGYG000004899_00334;MGYG000002478_04117;MGYG000001666_02224;MGYG000000236_00388;MGYG000000243_00095;MGYG000004763_00186;MGYG000002438_04196 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 0.8181818181818182 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001345_00428 0.045454545454545456 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 1340173 0 2010835 0 2047239 1162736 0 1715113 1286487 0 2793476 0 1676186 1692493 1890145 1843789 0 0 1791846 0 0 803696 0 975538 0 1404099 1120195 0 1306457 1253042 0 0 1514251 1422095 1276344 0 1069632 1588946 479259 0 600293 0 586271 730476 0 927319 721927 0 635469 0 526499 557427 737325 541898 0 0 514180 0 0 631140 0 0 0 794167 922946 0 685111 574476 0 0 378402 712327 937472 0 470399 636321 0 0 610781 0 484026 0 0 493076 0 0 467452 0 0 0 0 539974 0 0 0 0 0 0 0 0 0 0 0 0 260934 1156441 0 0 0 0 0 0 586530 484537 1510523 0 1883658 0 1978122 2088508 0 1692808 1381177 0 2041403 0 2106300 1651362 1649605 2360564 0 0 1596604 0 0 1684372 0 1742473 0 1513562 1625973 0 1349414 1543801 0 0 1367307 1440920 1986992 0 1439852 1520313 401582 0 0 0 470484 0 0 426153 601580 0 367200 0 616586 444406 448282 777386 0 0 543801 0 0 666002 0 687063 0 0 584763 0 0 335969 0 0 0 812964 514384 0 0 655918 +(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHASIRPFVLDAEEQK MGYG000001345_00428;MGYG000000196_04414;MGYG000002561_01024;MGYG000000013_01171;MGYG000001461_03964;MGYG000002549_02787;MGYG000000029_01835;MGYG000002455_00144;MGYG000001780_02881;MGYG000003681_00938;MGYG000001346_02526;MGYG000001337_03683;MGYG000001313_00862;MGYG000004899_00334;MGYG000002478_04117;MGYG000000236_00388;MGYG000000243_00095 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001345_00428 0.058823529411764705 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 2030102 1890434 2465395 0 1911877 1885542 0 2694847 0 0 3364054 2662096 0 2348038 0 3123768 2164002 1628163 1739843 1603675 0 1886198 1885258 2280436 1806741 2226876 2556018 1509760 3008937 0 2977698 2191038 2811130 0 2147713 3165241 1960024 2499254 2147419 1498380 2350267 0 2764341 3136175 0 3232925 0 0 3912292 3479919 0 3277605 0 4070064 2585267 0 2559973 2385390 0 2713206 2051674 1773478 3303296 3377262 2450029 1120672 1979230 0 1883194 2663150 2098086 0 2397160 2741616 2973026 2052975 2009260 1199554 2323196 0 2966702 2365295 0 1583005 0 0 4383181 2995617 0 2060614 0 2800591 1816159 4143123 1726012 1469896 0 1520128 3262223 2372159 2078243 1964404 1710192 3096681 2046355 0 2880507 1551141 1499316 0 1943054 2802343 1975411 2453815 478677 336756 485024 0 394633 294343 0 484774 0 0 733137 747722 0 720123 0 276661 427180 0 560788 496835 0 282545 603703 0 844212 975131 796499 0 218068 0 355365 893454 256859 0 709744 858275 326322 335888 1484881 1173375 594762 0 2435096 1886159 0 1923120 0 0 3566517 1500104 0 1297237 0 1995356 1502428 5006073 1451043 1957663 0 2365704 4570755 1862552 1824980 1718653 1583576 3617850 1904644 0 1708248 1410969 1158431 0 1821904 1288753 1520659 1519066 +(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHAVIRPV MGYG000002989_02129;MGYG000000249_01618;MGYG000001602_02095;MGYG000000133_02129;MGYG000002279_02008;MGYG000000038_01290;MGYG000001496_03305;MGYG000001710_03430;MGYG000000164_01756;MGYG000001338_02036;MGYG000000002_01844;MGYG000002945_01470;MGYG000001310_00851;MGYG000001374_00733 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 0.35714285714285715 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002989_02129 0.07142857142857142 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 715116 0 0 957365 0 0 0 0 1290407 0 0 0 1237681 0 0 0 0 1048848 0 811325 0 0 0 0 0 0 0 269821 0 1323105 0 0 0 0 0 614023 0 0 530793 0 0 504862 0 0 0 0 344969 0 0 0 392454 0 0 0 0 401547 0 345511 0 339633 0 0 0 0 0 621877 0 1034514 481179 0 0 0 0 278230 0 0 273477 0 0 549817 0 0 0 0 0 0 0 0 396899 0 0 0 0 337957 0 0 0 443306 0 0 0 0 0 0 0 903237 628257 0 0 0 0 0 0 0 1353810 0 0 607282 0 0 0 0 829567 0 0 0 0 0 0 0 0 534058 0 1073770 0 650998 0 0 0 0 0 782034 0 2110155 1056675 0 0 0 0 1053609 0 0 957021 0 0 678728 0 0 0 0 682622 0 0 0 529830 0 0 0 0 230890 0 749061 0 644492 0 0 0 0 0 0 0 3786853 1452297 0 0 0 0 0 +(Pyro-carbamidomethyl)CAYVC(Carbamidomethyl)PHAVIRPVALTAEEAANAPEGMK MGYG000001338_02036;MGYG000000200_00183 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001338_02036 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2210021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDAYAEHWAPK MGYG000001338_03293 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Radical SAM domain protein 1.0 atsB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,Radical_SAM,SPASM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03293 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 533111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432713 0 0 0 0 0 0 0 1526639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1306850 475147 0 0 0 0 0 0 0 782316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588577 0 0 0 0 0 0 0 647851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 794617 247711 0 0 0 0 0 0 0 643601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 574805 548441 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDC(Carbamidomethyl)GEQLHK MGYG000004763_02275;MGYG000002935_02168;MGYG000000003_02146;MGYG000000243_01797;MGYG000003279_01847;MGYG000002171_02994;MGYG000002478_00161;MGYG000002549_04025 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,4NF6I@976|Bacteroidetes,2FNS0@200643|Bacteroidia,4AN9P@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 H 1.0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate 1.0 ribBA 0.75 - 1.0 3.5.4.25,4.1.99.12 1.0 ko:K14652 1.0 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 1.0 M00125,M00840 1.0 R00425,R07281 1.0 RC00293,RC01792,RC01815,RC02504 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHBP_synthase,GTP_cyclohydro2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004763_02275 0.125 GTP cyclohydrolase II. | 3,4-dihydroxy-2-butanone-4-phosphate synthase. guanosine triphosphate cyclohydrolase II. | L-3,4-dihydroxybutan-2-one-4-phosphate synthase. The enzyme, found in prokaryotes and some eukaryotes, hydrolytically cleaves the C-N bond at positions 8 and 9 of GTP guanine, followed by a subsequent hydrolytic attack at the base, which liberates formate, and cleavage of the alpha-beta phosphodiester bond of the triphosphate to form diphosphate.-!-The enzyme continues with a slow cleavage of the diphosphate to form two phosphate ions.-!-The enzyme requires zinc and magnesium ions for the cleavage reactions at the GTP guanine and triphosphate sites, respectively.-!-It is one of the enzymes required for flavin biosynthesis in many bacterial species, lower eukaryotes, and plants. cf. EC 3.5.4.16, EC 3.5.4.29, and EC 3.5.4.39. | The reaction involves an intramolecular skeletal rearrangement, with the bonds in D-ribulose 5-phosphate that connect C-3 and C-5 to C-4 being broken, C-4 being removed as formate and reconnection of C-3 and C-5.-!-The phosphorylated four-carbon product (L-3,4-dihydroxybutan-2-one 4-phosphate) is an intermediate in the biosynthesis of riboflavin. GTP + 4 H2O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + formate + 3 H(+) + 2 phosphate. | D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+). 1.0 1.0 1.0 1.0 Riboflavin metabolism|Folate biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K14652:ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25] 1.0 none 1.0 853249 0 1205793 0 1163447 0 0 0 0 0 0 0 1025123 0 0 1117753 0 0 0 0 0 0 0 0 0 677554 0 0 0 0 0 0 1051640 0 0 0 847541 1140965 629036 0 728998 0 795769 0 0 0 0 0 0 0 765757 0 0 782859 0 0 0 0 0 0 0 0 0 755101 0 0 0 0 0 0 623045 0 0 0 690495 735314 624479 0 861762 0 1017967 0 0 0 0 0 0 0 815784 0 0 650825 0 0 0 0 0 0 0 0 0 700717 0 0 0 0 0 0 584179 0 0 0 630164 777971 364325 0 228787 0 255149 0 0 0 0 0 0 0 413389 0 0 254405 0 0 0 0 0 0 0 0 0 533598 0 0 0 0 0 0 345437 0 0 0 512071 0 476058 0 280949 0 719349 0 0 0 0 0 0 0 905534 0 0 582665 0 0 0 0 0 0 0 0 0 533038 0 0 0 0 0 0 374621 0 0 0 603571 360879 +(Pyro-carbamidomethyl)CDEMEQAKVK MGYG000000243_01586 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0AS@200643|Bacteroidia,4AMX1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MbeB_N,TPR_1,TPR_11,TPR_16,TPR_17,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01586 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 1755067 0 1001328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1754597 0 0 0 0 1599333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359899 0 146845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDFNVPLK MGYG000002492_01380;MGYG000004552_00730;MGYG000000989_01451;MGYG000000262_01196;MGYG000003486_02012;MGYG000003628_01098;MGYG000000325_00585;MGYG000002854_00823;MGYG000000909_00645;MGYG000003684_03801;MGYG000001707_00062;MGYG000000193_03246;MGYG000000118_02693;MGYG000002528_00366;MGYG000004667_02165;MGYG000000181_00012;MGYG000001814_01254;MGYG000002946_02880;MGYG000000404_00343;MGYG000002966_00074;MGYG000004271_00555;MGYG000004087_02289;MGYG000001553_02341;MGYG000000233_00344;MGYG000000198_04064;MGYG000000359_00927;MGYG000002445_01919;MGYG000002989_02172;MGYG000001479_00351;MGYG000000301_01011;MGYG000000258_00429;MGYG000001186_01924;MGYG000001199_01004;MGYG000000076_03636;MGYG000000255_01167;MGYG000000154_00118;MGYG000000312_01507;MGYG000000204_00777;MGYG000000378_01265;MGYG000004740_01467;MGYG000004519_00424;MGYG000002517_01027;MGYG000000179_02085;MGYG000000087_02748;MGYG000001617_03190;MGYG000000245_03070;MGYG000001423_00990;MGYG000002670_00852;MGYG000001619_01735;MGYG000001683_01828;MGYG000000383_00714;MGYG000000271_03251;MGYG000004863_01610;MGYG000001493_05256;MGYG000000133_02282;MGYG000004735_01945;MGYG000000489_00504;MGYG000002289_02222 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 0.43103448275862066 186801|Clostridia 1.0 F 0.8620689655172413 Belongs to the phosphoglycerate kinase family 0.6379310344827587 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01380 0.017241379310344827 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 267720 0 0 290103 0 71394 92272 102266 236474 207630 0 145871 0 208621 317437 85672 0 0 89859 183845 247527 190160 0 64662 101304 255378 71448 0 0 0 0 0 0 193914 0 279199 231582 0 144301 46528 0 139802 0 0 162107 68255 159529 145657 0 157961 0 64833 112774 0 0 0 157592 92498 0 0 0 0 0 141825 92226 0 0 0 0 0 59822 0 0 54669 59141 0 292109 0 59443 273017 0 90777 192004 143815 67561 189160 0 175309 0 272710 316000 184354 0 0 214788 140624 276629 128273 0 101102 226365 251332 212492 0 0 0 0 0 83925 175737 0 176957 221771 0 701033 127062 281457 561132 0 246630 410048 508412 595958 218290 0 343543 0 826132 674538 83867 0 0 495788 770147 522593 54050 0 82832 463640 492761 525745 0 0 0 0 0 242106 606167 0 762148 960690 215092 1262542 648218 872922 493046 0 826609 1216371 1069799 1094199 1213865 0 803561 0 1028562 1395063 877624 0 0 1432758 997222 985511 880281 0 634939 1139670 980658 907642 0 0 0 0 0 692422 1216467 0 854585 701035 631819 +(Pyro-carbamidomethyl)CDFNVPLKDGK MGYG000001186_01924;MGYG000000245_03070;MGYG000002670_00852;MGYG000001619_01735;MGYG000002492_01380;MGYG000004740_01467;MGYG000000271_03251;MGYG000000262_01196;MGYG000000404_00343;MGYG000004271_00555;MGYG000004519_00424;MGYG000000325_00585;MGYG000000233_00344;MGYG000000909_00645;MGYG000001141_01007;MGYG000000193_03246 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 0.6875 186801|Clostridia 1.0 F 0.8125 Belongs to the phosphoglycerate kinase family 0.75 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001186_01924 0.0625 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 1635393 1494016 887899 2188640 1281483 1437967 1957109 1739353 1822713 2004258 2450647 0 1719525 1523252 0 1648961 1926478 1397183 1221834 1641924 0 1707896 730853 1109690 2105785 1515595 1677134 862425 1394503 0 776943 0 967135 2231618 1373876 1649232 1564983 555980 2531796 1918174 2000783 2560429 2626148 1567152 2541452 2240900 2012781 2131329 2597612 0 2512586 1834187 0 1843067 2038813 5033172 1767912 2075519 0 1367643 3154233 1782917 2174168 1911600 1965924 4430369 2319936 0 1492470 0 2019998 2329356 2308826 2361943 1783404 2044105 2339828 1798525 4244967 3120875 1440287 1579681 1345674 2573666 1511765 1830935 2221243 0 2414253 1995282 0 3082603 2126296 1451005 2126304 2010957 0 2216496 2564119 1112117 2354680 2190570 2567084 3429103 1256014 0 1320059 0 4038744 2928958 2572446 1459454 1965836 4845427 483358 593285 432490 846360 569940 602375 803326 636188 464375 586034 568675 0 577139 512003 0 841163 789169 519032 408264 752101 0 353930 0 679362 478029 341230 653035 411384 745604 0 539699 0 560701 413493 541972 487409 422408 495289 1668329 1281113 1106205 1005457 774068 1344120 2209767 1543647 1656737 1477360 1097334 0 896035 853625 0 1045743 1452256 1267289 1831579 1897657 0 701801 1591093 1183146 1529734 1435072 1309783 1809643 1355188 0 1071406 0 1282247 1900576 1313663 1332167 1580687 1168242 +(Pyro-carbamidomethyl)CDFNVPLKDGKITDENR MGYG000000271_03251;MGYG000000404_00343;MGYG000000262_01196;MGYG000004271_00555;MGYG000002670_00852;MGYG000002492_01380;MGYG000001141_01007;MGYG000004740_01467 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 0.5 186801|Clostridia 1.0 F 0.75 Belongs to the phosphoglycerate kinase family 0.625 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_03251 0.125 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDFNVPLKDGQITDENR MGYG000002528_00366;MGYG000000118_02693 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3XYK6@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00366 0.5 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 425961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1815829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDFNVPLKEGK MGYG000000301_01011;MGYG000001617_03190;MGYG000001199_01004;MGYG000000133_02282;MGYG000000181_00012;MGYG000000076_03636;MGYG000000154_00118;MGYG000002445_01919;MGYG000001707_00062 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3XYK6@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 0.5555555555555556 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_01011 0.1111111111111111 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 488351 0 0 0 422270 0 0 380863 0 0 0 506900 0 0 0 547635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 737380 0 0 0 0 0 744001 0 0 0 0 1255475 1011917 646724 701521 951757 0 0 696048 0 676152 0 0 0 1057741 871455 885539 0 0 0 0 0 0 0 0 0 753338 0 0 0 0 0 0 0 0 0 0 264714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5812202 0 6663259 9241415 0 3600909 7966056 0 0 8225071 5679005 5284605 4598155 7959586 5610581 4052405 5533501 0 5640857 0 7492416 2949381 0 2802251 4561146 3830277 6289761 0 0 0 0 0 10976102 0 0 4955674 3098803 4670060 +(Pyro-carbamidomethyl)CDFNVPLKEGVIQNYNR MGYG000004087_02289;MGYG000000198_04064;MGYG000000179_02085;MGYG000002946_02880 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,21XSB@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Phosphoglycerate kinase 1.0 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004087_02289 0.25 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 500551 0 0 0 0 0 0 461436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261473 362430 0 0 0 0 0 0 0 0 0 0 0 0 0 267970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114327 0 0 0 0 240574 0 0 0 0 0 0 0 0 0 490573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457652 974591 0 0 0 243122 0 0 197003 0 0 0 0 0 0 67674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363778 0 0 0 0 0 0 777428 0 0 0 0 0 0 1300245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1405195 1687205 0 0 0 1034807 +(Pyro-carbamidomethyl)CDFNVPLKNGEITDETR MGYG000003486_02012;MGYG000002517_01027;MGYG000000255_01167;MGYG000001814_01254;MGYG000002989_02172 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 0.8 186801|Clostridia 1.0 F 0.8 Belongs to the phosphoglycerate kinase family 0.8 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003486_02012 0.2 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 438542 0 0 1038103 531367 0 0 0 0 1061792 0 0 0 0 764050 585648 1207985 0 0 883755 0 0 0 0 863185 789255 0 0 0 0 0 0 0 0 0 867042 947599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480570 0 0 0 0 0 346016 0 0 0 0 455178 0 0 0 0 0 0 0 0 0 417448 569377 0 0 0 0 0 0 0 0 0 599357 614280 0 2639783 0 0 3671224 1341769 0 0 0 0 1475402 0 1974294 0 0 3778300 1260422 2169580 0 0 2849356 0 0 0 0 3455939 3093505 0 0 0 0 0 0 0 0 0 3344550 3429087 0 2668899 0 0 0 2176550 0 0 0 0 4144301 0 2699328 0 0 4177120 2250479 3725626 0 0 2533444 0 0 0 0 4275823 3948290 0 0 0 0 0 0 0 0 0 4517391 5410455 0 +(Pyro-carbamidomethyl)CDFNVPLQDGK MGYG000000080_03114;MGYG000000212_01475;MGYG000000171_00851;MGYG000000139_00882;MGYG000000200_02456;MGYG000001714_01797;MGYG000000125_00366;MGYG000000249_01353;MGYG000001338_02546;MGYG000000002_02119;MGYG000001543_00857;MGYG000000050_00594;MGYG000002298_02411;MGYG000000806_01931;MGYG000000263_01340;MGYG000000252_01325;MGYG000000142_01978 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H2GV@909932|Negativicutes 0.6470588235294118 909932|Negativicutes 0.6470588235294118 G 0.7647058823529411 Belongs to the phosphoglycerate kinase family 0.7647058823529411 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_03114 0.058823529411764705 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 546048 1033486 838531 0 688651 913810 0 756177 0 0 1292367 0 0 0 0 0 499931 749524 0 204793 0 1340362 535565 0 0 378599 391657 948801 1020326 0 0 790403 443373 301436 0 311796 182935 531364 524212 1623278 450166 0 1237787 492572 0 1119046 548978 0 758819 0 0 0 0 0 1003501 1728047 0 1061872 0 0 812898 633450 0 708923 778927 1396358 1210959 0 2406400 1309434 511216 676349 0 671870 492268 249111 197512 1196050 376075 0 0 339692 0 359615 204022 0 254938 0 0 0 0 0 563801 201403 0 349288 0 700774 538205 164613 0 692025 392094 718402 258577 0 421503 1210942 562271 485410 0 321235 287622 467919 0 1289885 0 0 655145 0 0 0 206493 0 316480 0 0 0 0 0 215714 0 0 204507 0 0 0 222172 0 0 189858 0 805727 0 1012353 815538 0 0 0 248558 0 600839 321253 1511306 1178506 0 0 605114 0 424491 219512 0 575263 0 0 0 0 0 289975 316393 0 0 0 135690 622467 573207 0 163853 404723 959219 1163684 0 859365 1132887 2091440 398920 0 443827 172829 779171 +(Pyro-carbamidomethyl)CDFNVPLQDGKITDENR MGYG000001338_02546;MGYG000000080_03114;MGYG000000212_01475;MGYG000000171_00851;MGYG000000002_02119;MGYG000000139_00882;MGYG000000050_00594;MGYG000002298_02411;MGYG000000200_02456;MGYG000001714_01797;MGYG000000142_01978 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H2GV@909932|Negativicutes 0.7272727272727273 909932|Negativicutes 0.7272727272727273 G 0.9090909090909091 Belongs to the phosphoglycerate kinase family 0.8181818181818182 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02546 0.09090909090909091 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 552386 0 0 868671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1427524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 627018 0 0 454367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDFNVPMK MGYG000001255_00368;MGYG000001300_02037;MGYG000004221_01544;MGYG000002274_01739;MGYG000000022_00457;MGYG000003937_01847;MGYG000003921_00578;MGYG000002105_00517;MGYG000000084_00216;MGYG000003899_01395;MGYG000002641_00592;MGYG000002098_01090;MGYG000002040_00807 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae 0.9230769230769231 186801|Clostridia 1.0 G 0.9230769230769231 Phosphoglycerate kinase 0.9230769230769231 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001255_00368 0.07692307692307693 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189131 0 0 0 276146 0 0 0 0 0 0 342259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161387 0 0 0 0 229102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154619 0 0 0 0 0 0 89474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128784 0 0 0 0 103550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDFNVPMKDGVITNENR MGYG000001255_00368;MGYG000002272_00148;MGYG000001300_02037;MGYG000000039_00980;MGYG000000195_00272;MGYG000002223_00500;MGYG000002274_01739;MGYG000003899_01395;MGYG000000022_00457;MGYG000002641_00592;MGYG000002040_00807 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Phosphoglycerate kinase 1.0 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001255_00368 0.09090909090909091 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 1229735 1393595 2575577 1856177 530301 1152534 1041475 0 1484368 1385351 0 747258 0 1771360 1173974 1483294 1585251 1513597 2212681 1851306 0 1158028 1284511 651494 1461735 1297009 1173366 563492 0 363530 0 622054 2257715 2207160 0 1168718 888446 2112040 1879741 2308513 2642496 2490091 1625230 2327701 2913506 0 1977258 625667 0 2402004 0 2769167 2624024 1392601 2710980 1291268 3073123 2966699 0 1751042 2130644 2095749 1030065 2459284 2320835 2346814 0 1902990 0 2412580 2602166 1941335 0 1964957 1845778 1846070 0 367679 522971 0 432827 0 492741 0 812854 0 0 0 0 0 0 486317 0 734041 0 332571 0 0 1413455 0 0 0 411788 1938593 0 0 0 0 0 483044 0 572890 455688 0 1363567 1167418 2366643 1301395 1542605 2122176 2690312 0 1594280 1259528 0 2366409 0 993021 1554111 1702536 1303236 974124 2510071 1584694 0 1261664 1569782 820490 2048001 1469294 1854325 1108584 0 1978116 0 1529640 2111018 1481191 0 692287 1639533 1665588 0 0 482865 0 0 0 437743 0 0 376280 0 0 0 399882 0 340060 0 1356244 0 0 0 0 1967022 0 0 345272 0 1431697 0 0 0 318292 537861 0 0 448238 0 482747 +(Pyro-carbamidomethyl)CDGADEAEALAAAIELIK MGYG000003266_00144;MGYG000002961_01622;MGYG000000188_00406;MGYG000003122_01007;MGYG000003274_01389;MGYG000000802_00030;MGYG000001636_01240;MGYG000002919_00987;MGYG000001086_00655;MGYG000004875_01407;MGYG000002065_00911 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1925@1|root,COG1925@2|Bacteria,2H0K7@201174|Actinobacteria,4CWQ1@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 PTS HPr component phosphorylation site 1.0 - 1.0 - 1.0 - 1.0 ko:K11189 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003266_00144 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 K11189:- 1.0 none 1.0 0 560741 0 0 0 0 0 0 0 0 555093 1901831 0 0 0 3265350 0 0 0 0 0 0 0 0 0 0 0 0 0 1756843 0 0 0 0 0 0 0 0 0 795758 0 0 0 0 0 0 0 0 892677 0 0 0 0 1169202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546490 0 0 0 3521115 0 0 0 0 0 0 0 0 0 0 0 0 0 669858 1026947 0 0 0 0 0 0 0 0 3358796 0 0 0 0 0 0 0 0 10250478 5320202 0 0 0 8659493 0 0 0 0 0 0 0 0 0 0 0 0 0 6074156 7292930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1328598 0 0 0 2252777 0 0 0 0 0 0 0 0 0 0 0 0 0 737563 1501596 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDGDNVAPIFPK MGYG000000179_00066;MGYG000000198_00289 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG1744@1|root,COG1744@2|Bacteria,1U4NN@1239|Firmicutes,24CRY@186801|Clostridia 0.5 186801|Clostridia 1.0 S 1.0 Basic membrane protein 0.5 - 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_00066 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07335:bmpA, bmpB, tmpC; basic membrane protein A and related proteins 1.0 none 1.0 169880 0 0 0 0 346995 0 0 0 0 0 0 0 0 290944 0 404588 0 600105 464117 0 0 0 0 0 698257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170536 0 0 0 0 0 0 0 0 314572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138852 0 0 0 0 0 0 0 0 0 0 307893 0 0 0 0 0 0 0 0 0 0 0 205929 0 0 0 0 0 0 0 0 0 2693890 0 0 3451582 0 1063217 0 0 2667907 3943394 0 0 0 0 3189448 0 2136828 0 2444869 1854264 0 1217033 0 1183652 0 3181600 4017593 0 5528318 0 2197485 0 0 2503465 0 0 2403122 0 +(Pyro-carbamidomethyl)CDIKQEWADGGKEK MGYG000002517_00541;MGYG000000154_01283 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00541 0.5 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 0 114971 0 0 0 175566 0 0 0 0 0 0 0 0 0 0 213654 0 0 0 0 0 89210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1383176 0 0 2698934 0 0 0 2087673 3044311 0 0 0 0 2322485 0 1367405 2637042 0 2516718 2740547 0 0 0 0 1712894 1229350 2159033 0 0 0 0 0 0 0 2287232 0 1625194 0 117142 0 0 111760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDIKQEWAENGLAK MGYG000001300_00294;MGYG000003166_01335 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,3WHJ6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase 1.0 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00294 0.5 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDTSSAEFQAR MGYG000000179_00909 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,21XKR@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_00909 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481684 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDVAALVGK MGYG000000074_01945 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia,22VD9@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01945 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134435 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDVDDNDELTGR MGYG000000243_02652 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3118@1|root,COG3118@2|Bacteria,4NQ5B@976|Bacteroidetes,2FTV5@200643|Bacteroidia,4ARCY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Belongs to the thioredoxin family 1.0 trxA 1.0 - 1.0 - 1.0 ko:K03671 1.0 ko04621,ko05418,map04621,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 Thioredoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02652 1.0 - - - - 1.0 1.0 1.0 1.0 NOD-like receptor signaling pathway|Fluid shear stress and atherosclerosis 1.0 K03671:TXN, trxA; thioredoxin 1.0 none 1.0 0 0 588268 483496 383419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 725092 0 0 428413 0 650542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476509 467211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825558 0 0 0 0 641661 0 398253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339755 0 0 444211 0 167346 +(Pyro-carbamidomethyl)CDVDTMKTER MGYG000002438_02511 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0673@1|root,COG0673@2|Bacteria,4NGHJ@976|Bacteroidetes,2FQNW@200643|Bacteroidia,22ZVG@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase family, NAD-binding Rossmann fold 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C 1.0 - 1.0 GH109 1.0 - 1.0 - 1.0 MGYG000002438_02511 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CDVESTKANQ MGYG000002171_02571;MGYG000000243_02590 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1256@1|root,COG1256@2|Bacteria,4PKVX@976|Bacteroidetes,2G05N@200643|Bacteroidia,4AWF1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 bacterial-type flagellum assembly 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_02571 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 1328088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150791 0 0 0 0 939048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CEAAIAAGKFDDEIVPVPVK MGYG000002670_01511;MGYG000003694_00877;MGYG000002492_00657 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002670_01511 0.3333333333333333 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8514735 0 7331263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12955829 0 0 0 0 13014455 0 0 52572651 0 24983199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8807164 0 0 0 0 53798382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12605380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CEAAIAAGKFDDEIVPVPVKVK MGYG000002492_00657 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00657 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1190017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1208085 0 0 0 0 997363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CEDDKLDVALDVIKK MGYG000002293_01994;MGYG000003697_01048;MGYG000002834_02633 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01994 0.3333333333333333 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 66701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177854 0 0 0 0 75966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 555374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341470 0 0 0 0 773914 0 0 0 0 457599 0 0 0 0 389119 0 0 0 0 431208 0 0 95852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CEEFKTEEGQKR MGYG000002528_01287 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,2682U@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01287 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 0 0 0 0 0 290005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319513 0 636891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1107287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2201811 0 711499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CEFDAIHLTR MGYG000002517_01855 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 'glutamate synthase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4,Fer4_20,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01855 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 374488 297545 0 500668 0 0 374665 0 462753 0 0 0 0 0 0 0 0 0 324691 0 0 0 0 616165 221390 0 0 0 0 0 0 0 0 0 186051 278308 246406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1019152 0 197409 807494 386641 216706 581128 1054091 956324 632012 0 432951 0 1195038 955398 422407 671004 0 742236 1011643 879647 0 0 0 1087239 1072600 1260534 0 0 916061 0 0 173036 752461 1261362 873234 1154052 246904 725614 346679 522718 0 354892 449496 819476 617277 784200 848332 0 593343 0 1264595 1050963 444204 897138 0 619479 609023 740706 579266 0 496941 1061853 766751 838489 0 0 669579 0 0 370046 932029 866506 997880 1053082 597619 +(Pyro-carbamidomethyl)CEGDTGSPEVQVAVLTAR MGYG000000002_01947;MGYG000000171_00631;MGYG000002298_00958;MGYG000002966_03339;MGYG000000133_01737;MGYG000000201_02701;MGYG000004733_03076;MGYG000000212_01974 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4H3DG@909932|Negativicutes 0.75 909932|Negativicutes 0.75 M 0.75 Belongs to the UDP-glucose GDP-mannose dehydrogenase family 0.75 - 0.75 - 1.0 - 1.0 ko:K02474 0.75 ko00520,map00520 0.75 - 0.75 R06894 0.75 RC00291 0.75 ko00000,ko00001,ko01000,ko01005 0.75 - 1.0 - 1.0 - 1.0 UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000002_01947 0.125 - - - - 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 0.75 K02474:wbpO; UDP-N-acetyl-D-glucosamine/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-] 0.75 none 1.0 0 0 246000 0 0 0 0 411501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339018 0 0 0 0 0 0 0 0 0 0 269646 0 523496 0 0 0 0 0 0 0 0 0 0 0 0 504667 0 0 0 304508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295956 0 0 0 0 0 0 0 0 0 761595 883221 794343 1331701 0 0 1119709 605159 0 1213306 0 663690 0 2207160 0 456877 0 0 0 0 937902 0 0 0 0 748717 0 0 1409106 0 0 885418 1547551 706956 0 963157 560596 820970 +(Pyro-carbamidomethyl)CEPNKLDELLHPVFDKK MGYG000004797_01193;MGYG000002560_01450;MGYG000002478_03849 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000004797_01193 0.3333333333333333 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 1300317 0 0 0 0 0 0 0 0 0 0 1724115 0 669612 0 0 0 0 887260 0 0 0 0 1137518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1042419 0 0 0 0 0 0 0 0 0 0 1305192 0 500639 0 0 0 0 476843 0 0 0 0 495528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675986 0 0 0 0 0 0 0 0 0 0 610608 0 0 0 0 0 0 530867 0 0 0 0 596119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41697 0 0 0 0 0 0 0 0 0 0 58335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1285488 0 0 0 0 0 0 0 0 0 0 1068479 0 1049353 0 0 0 0 917363 0 0 0 0 1030596 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CETDFVAK MGYG000003645_01304;MGYG000002476_01244;MGYG000003868_00871;MGYG000002291_02397;MGYG000002205_01448;MGYG000002905_00241;MGYG000001708_01075;MGYG000000442_00899;MGYG000004769_00833;MGYG000000100_00889;MGYG000001306_01209;MGYG000002246_00674;MGYG000001783_00059;MGYG000004754_01676;MGYG000002171_01964;MGYG000003926_00749;MGYG000004797_01413;MGYG000003521_01644;MGYG000004763_01244;MGYG000002438_01052;MGYG000002120_01117;MGYG000003693_02548;MGYG000004464_00789;MGYG000002540_02892;MGYG000001552_01770;MGYG000000170_01177;MGYG000002930_00993;MGYG000000098_01947;MGYG000002935_00870;MGYG000000358_00459;MGYG000002236_01429;MGYG000000413_02556;MGYG000003259_00703;MGYG000002525_02210;MGYG000002478_01739;MGYG000001789_02687;MGYG000004105_00545;MGYG000001489_01081;MGYG000000243_02465;MGYG000000174_01105;MGYG000003857_00549;MGYG000000273_00241;MGYG000001925_02037;MGYG000003446_00288;MGYG000001503_01830 domain d__Bacteria 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 0.35555555555555557 976|Bacteroidetes 0.7333333333333333 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 0.6666666666666666 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 0.9333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003645_01304 0.022222222222222223 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 368531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CETDFVAQNADFVK MGYG000002281_00012;MGYG000003312_00467;MGYG000000013_03147;MGYG000004876_02408;MGYG000001337_04207;MGYG000004019_01939;MGYG000001661_02572;MGYG000001378_03196;MGYG000001313_02981;MGYG000003252_02162;MGYG000000105_01496;MGYG000001345_01370;MGYG000000196_04091;MGYG000003681_02139;MGYG000000236_02875;MGYG000000029_01191 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_00012 0.0625 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 630195 0 0 0 0 612665 1083075 528668 822875 0 2117905 0 0 0 0 745486 0 0 0 707874 0 767344 0 915427 0 498298 0 0 0 0 0 0 0 0 0 945569 719171 0 695119 0 0 0 0 970554 585011 1063718 840835 0 1429547 0 0 0 0 793608 0 0 0 736941 0 822445 0 374491 0 900877 0 0 0 0 0 0 0 0 0 730446 758450 0 1008985 0 0 0 0 976541 1008216 817491 1081971 0 709045 0 0 0 0 311964 0 0 0 501494 0 288102 0 1525755 0 951151 0 0 0 0 0 0 0 0 0 1033377 600345 0 813665 0 0 0 0 1221102 1454283 940577 934112 0 1417764 0 0 0 0 1038978 0 0 0 818385 0 1610961 0 692027 0 1453615 0 0 0 0 0 0 0 0 0 1486834 1373953 0 0 0 0 0 0 970642 578590 924156 881937 0 1661715 0 0 0 0 796912 0 0 0 1344494 0 402661 0 1047486 0 512532 0 0 0 0 0 0 0 0 0 683649 520490 0 +(Pyro-carbamidomethyl)CETLGVAC(Carbamidomethyl)EK MGYG000002312_01590;MGYG000002756_01700;MGYG000000200_00061;MGYG000000184_03367;MGYG000000142_02496;MGYG000004735_00338;MGYG000001698_00104;MGYG000002216_01774;MGYG000001338_02420;MGYG000004785_01735;MGYG000000212_01925;MGYG000000213_03796;MGYG000000216_02775 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3XZ53@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate 1.0 folD 1.0 - 1.0 1.5.1.5,3.5.4.9 1.0 ko:K01491 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R01220,R01655 1.0 RC00202,RC00578 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 THF_DHG_CYH,THF_DHG_CYH_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002312_01590 0.07692307692307693 methylenetetrahydrofolate dehydrogenase (NADP(+)). | methenyltetrahydrofolate cyclohydrolase. - - (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10- methenyltetrahydrofolate + NADPH. | (6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H(+). 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01491:folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9] 1.0 none 1.0 0 0 627914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343935 0 0 0 0 227181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513894 0 0 0 0 362992 0 0 483449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379387 0 0 0 0 252745 0 0 708429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1162202 0 0 0 0 595089 +(Pyro-carbamidomethyl)CFAFLAGHESFAAAEGAIK MGYG000000013_02686;MGYG000003420_01320;MGYG000001658_01116;MGYG000002854_01085;MGYG000003521_00824;MGYG000002455_00321;MGYG000004824_01069;MGYG000002444_01680;MGYG000000269_00015;MGYG000003570_02445;MGYG000000781_01514;MGYG000001400_01185;MGYG000004822_01055;MGYG000004561_02010;MGYG000000042_01753;MGYG000000196_00899;MGYG000004763_01967;MGYG000004493_00376;MGYG000004797_02907;MGYG000001423_03082;MGYG000000479_02090;MGYG000001925_01569;MGYG000001806_00888;MGYG000001346_01121;MGYG000000215_01600;MGYG000003535_01608;MGYG000001871_01775;MGYG000002293_01605;MGYG000000043_00846;MGYG000000273_02192;MGYG000003221_02162;MGYG000003470_00018;MGYG000003922_03053;MGYG000003693_01584;MGYG000001415_02505;MGYG000004699_02799;MGYG000002080_00203;MGYG000002275_01873;MGYG000002218_00562;MGYG000001770_01218;MGYG000001604_01691;MGYG000002834_01893;MGYG000002108_00627;MGYG000001697_00682;MGYG000002438_03055;MGYG000004464_00921;MGYG000000029_00187;MGYG000001378_03489;MGYG000000045_01847;MGYG000002281_03938;MGYG000001599_00424;MGYG000001763_00631;MGYG000002098_00644;MGYG000000707_02290;MGYG000001760_00836;MGYG000003446_01092;MGYG000004019_01333;MGYG000002478_02896 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.43103448275862066 976|Bacteroidetes 0.7586206896551724 S 1.0 Psort location Cytoplasmic, score 8.96 0.6724137931034483 - 0.9137931034482759 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_02686 0.017241379310344827 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 578828 0 0 0 0 0 0 0 0 0 0 0 0 14069114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733539 0 0 0 0 0 0 0 0 0 0 24833639 0 1431229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18005074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 22712349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8870748 0 0 0 0 0 0 0 0 0 0 58784960 0 +(Pyro-carbamidomethyl)CFDAANAAAEEKVEAVR MGYG000002478_04136 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002478_04136 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1669114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 345467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CFDAANAAAEEKVEAVRK MGYG000002478_04136 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002478_04136 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2] 1.0 none 1.0 825822 0 0 0 0 806050 0 0 0 0 0 0 968629 0 0 975558 0 752937 794557 0 0 850769 839597 862393 0 875570 0 1005039 0 0 0 0 0 0 962731 0 820365 0 528214 0 0 0 0 272962 0 0 0 0 0 0 766368 0 0 931031 0 272935 525150 0 0 299744 514363 742239 0 952417 0 521086 0 0 0 0 0 0 882138 0 638319 0 331243 0 0 0 0 353213 0 0 0 0 0 0 475352 0 0 438009 0 1025110 323091 0 0 278738 440239 123805 0 253041 0 450983 0 0 0 0 0 0 449521 0 232635 0 116603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 266655 0 0 0 0 0 0 0 509171 0 0 0 0 0 0 0 0 321208 0 102887 0 518608 0 0 0 0 796190 0 0 0 0 0 0 645432 0 0 493305 0 1247333 751398 0 0 488809 964072 513452 0 527053 0 1137539 0 0 0 0 0 0 1137485 0 1103808 0 +(Pyro-carbamidomethyl)CFDADELKR MGYG000002506_01728 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0584@1|root,COG0584@2|Bacteria,1MVWZ@1224|Proteobacteria,1RRBP@1236|Gammaproteobacteria,3XP14@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 glycerophosphoryl diester phosphodiesterase 1.0 glpQ 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 1.0 3.1.4.46 1.0 ko:K01126 1.0 ko00564,map00564 1.0 - 1.0 R01030,R01470 1.0 RC00017,RC00425 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECNA114_1301.ECNA114_2331,iECSF_1327.ECSF_2119 1.0 GDPD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_01728 1.0 glycerophosphodiester phosphodiesterase. glycerophosphoryl diester phosphodiesterase. Broad specificity for glycerophosphodiesters; glycerophosphocholine, glycerophosphoethanolamine, glycerophosphoglycerol and bis(glycerophospho)-glycerol are hydrolyzed. a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism 1.0 K01126:E3.1.4.46, glpQ, ugpQ; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 743052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CFDIGRDHYYYDDYENER MGYG000004797_02600;MGYG000002478_03184 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,2FMRY@200643|Bacteroidia,4AMCU@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glycosyl hydrolase 57 family 1.0 amyA 1.0 - 1.0 3.2.1.1 1.0 ko:K07405 1.0 ko00500,ko01100,map00500,map01100 1.0 - 1.0 R02108,R02112,R11262 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH57 1.0 - 1.0 Glyco_hydro_57 1.0 - 1.0 GH57 1.0 GH57 1.0 GH57 1.0 MGYG000004797_02600 0.5 alpha-amylase. glycogenase. Acts on starch, glycogen and related polysaccharides and oligosaccharides in a random manner; reducing groups are liberated in the alpha-configuration.-!-The term 'alpha' relates to the initial anomeric configuration of the free sugar group released and not to the configuration of the linkage hydrolyzed. Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units. 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Metabolic pathways 1.0 K07405:E3.2.1.1A; alpha-amylase [EC:3.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 752268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CFEIEKK MGYG000000301_01375;MGYG000004733_03272;MGYG000000251_00123;MGYG000000213_04019;MGYG000000133_01193;MGYG000001338_00282;MGYG000000200_01241;MGYG000000142_01828;MGYG000000031_00555;MGYG000000002_01111;MGYG000004735_01013 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3XYME@572511|Blautia 0.9090909090909091 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 1.1.1.38 1.0 ko:K00027 1.0 ko00620,ko01200,ko02020,map00620,map01200,map02020 1.0 - 1.0 R00214 1.0 RC00105 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_01375 0.09090909090909091 malate dehydrogenase (oxaloacetate-decarboxylating). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon metabolism|Two-component system 1.0 K00027:ME2, sfcA, maeA; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] 1.0 none 1.0 0 982240 1053343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207572 0 0 0 0 162201 0 0 0 0 0 0 0 0 0 633572 0 0 0 0 296226 0 1748492 699149 744423 0 0 1004776 0 0 0 0 0 0 446836 0 0 0 1279675 0 0 0 0 613570 0 0 0 0 864204 0 0 2103126 0 793945 0 0 0 0 1055564 0 1437994 742151 610371 0 0 449054 0 0 0 0 0 0 911498 0 0 0 383728 0 0 0 0 602562 0 0 0 0 646154 0 0 463957 0 1190736 0 0 0 0 600528 0 1064164 490542 394026 0 0 801417 0 0 0 0 0 0 451529 0 0 0 186195 0 0 0 0 0 0 0 0 0 484175 0 0 825165 0 690757 0 0 0 0 788600 0 1103540 1146862 2633557 0 0 1408069 0 0 0 0 0 0 1539282 0 0 0 207783 0 0 0 0 542537 0 0 0 0 511146 0 0 1131024 0 2156990 0 0 0 0 1057170 +(Pyro-carbamidomethyl)CFGALQR MGYG000000074_01490 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0612@1|root,COG0612@2|Bacteria,4NDXM@976|Bacteroidetes,2FNQC@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Belongs to the peptidase M16 family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M16C_assoc,Peptidase_M16,Peptidase_M16_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01490 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 242491 314158 0 286494 225132 0 161445 0 0 176615 0 0 0 206917 196224 0 163053 0 239157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55183 516045 0 716579 816888 0 1078974 0 0 139333 0 0 0 91083 71311 0 56150 0 527572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392394 58846 0 520615 407991 0 428646 0 0 409156 0 0 0 300732 292527 0 46863 0 330098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169859 334882 0 276186 359084 0 203052 0 0 244016 0 0 0 118109 257564 0 189411 0 66167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453583 317214 0 447040 506001 0 353137 0 0 398837 0 0 0 654952 610325 0 399446 0 270982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CFITNGK MGYG000000076_01275;MGYG000000217_01340;MGYG000004740_00273;MGYG000000205_02133;MGYG000000164_00686;MGYG000000153_01461;MGYG000001637_02229;MGYG000000255_01556;MGYG000001315_01868;MGYG000000489_01025;MGYG000002670_01509;MGYG000002492_00659;MGYG000000080_01475;MGYG000000018_00071;MGYG000000204_00801;MGYG000001777_01058;MGYG000002278_01893;MGYG000000312_02425;MGYG000000127_04022;MGYG000001793_01807;MGYG000000280_01471;MGYG000002945_00737;MGYG000000139_01931;MGYG000000136_00900;MGYG000000271_02102;MGYG000004271_00233;MGYG000000389_02149;MGYG000004039_00586;MGYG000004762_01001;MGYG000001186_01721;MGYG000002517_00542;MGYG000001319_02235;MGYG000000154_01282 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 0.45454545454545453 186801|Clostridia 1.0 C 0.7575757575757576 acyl-CoA dehydrogenase 0.5151515151515151 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000076_01275 0.030303030303030304 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 66130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191347 0 0 159529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210142 0 0 368960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388103 0 0 560046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CFIVTDSFLYK MGYG000002098_00441;MGYG000004733_00775;MGYG000000212_01362;MGYG000000287_00634;MGYG000002966_01058;MGYG000000031_00643;MGYG000000171_02770;MGYG000000142_00071;MGYG000000200_01803;MGYG000003822_00610;MGYG000001338_01157;MGYG000000216_02630;MGYG000002298_01049;MGYG000000133_00993;MGYG000000301_01128 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 0.8666666666666667 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 0.8666666666666667 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002098_00441 0.06666666666666667 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 252527 0 0 0 0 162014 0 0 0 0 115828 0 247476 172528 85626 0 0 0 0 86099 0 0 0 119389 0 0 0 0 0 158918 0 0 0 0 0 0 153423 0 426771 0 0 572054 304959 257654 228655 200960 0 0 1166597 0 265360 514776 0 0 192423 0 288162 321130 0 527404 0 269197 265709 0 251998 0 0 163693 546518 0 0 0 380333 218552 195284 0 188472 0 0 92916 337138 239062 426585 631544 0 0 513649 0 312231 395786 273004 0 174936 0 0 159606 0 164202 0 293469 234839 0 1306263 0 0 221166 441804 0 0 122998 176538 449479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187283 162154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481772 169998 0 0 189686 0 0 73117741 0 14168650 0 0 8480964 44461886 11253279 27077097 56062702 0 0 47685717 0 41642598 11505229 50355728 0 24727670 0 29685640 20454596 0 19698079 0 29051878 45790200 0 74985156 0 0 43380724 65875386 0 0 86085623 15805944 28108731 +(Pyro-carbamidomethyl)CFRDEDLR MGYG000004876_02985;MGYG000000133_00405;MGYG000004871_00028;MGYG000003376_01015;MGYG000000184_03179;MGYG000001346_00214;MGYG000000002_01263;MGYG000000013_03290;MGYG000002515_01154;MGYG000001337_02892;MGYG000000273_01761;MGYG000002293_01630;MGYG000000262_02041;MGYG000000312_01098;MGYG000000177_01950;MGYG000002298_01534;MGYG000000077_02526;MGYG000002477_02755;MGYG000004828_02136;MGYG000001306_01794;MGYG000002528_03034;MGYG000003697_02254;MGYG000000398_01746;MGYG000001338_02328;MGYG000002534_02980;MGYG000000229_00294;MGYG000000187_00052;MGYG000000212_01726;MGYG000004763_00125;MGYG000004558_00003;MGYG000000074_01068;MGYG000003022_00350;MGYG000003390_03348;MGYG000004502_00224;MGYG000002772_02118;MGYG000003352_01471;MGYG000004797_01951;MGYG000002492_02656;MGYG000002478_03690;MGYG000000412_00005;MGYG000002494_03433;MGYG000001345_03009;MGYG000000196_01400;MGYG000003273_01271;MGYG000002485_01149;MGYG000000142_01151;MGYG000004735_01033;MGYG000002960_00319;MGYG000000243_00388;MGYG000002024_00788;MGYG000002438_03185;MGYG000002992_00318;MGYG000004762_01202;MGYG000000028_01137 domain d__Bacteria 1.0 COG0173@1|root,COG0173@2|Bacteria,4NECY@976|Bacteroidetes,2FMCA@200643|Bacteroidia,4AMA8@815|Bacteroidaceae 0.2222222222222222 186801|Clostridia 0.42592592592592593 J 1.0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) 0.5740740740740741 aspS 1.0 - 0.9074074074074074 6.1.1.12 1.0 ko:K01876 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R05577 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 0.9074074074074074 GAD,Glu-tRNAGln,tRNA-synt_2,tRNA-synt_2d,tRNA_anti-codon 0.42592592592592593 - 1.0 - 1.0 - 1.0 GT83 1.0 MGYG000004876_02985 0.018518518518518517 aspartate--tRNA ligase. aspartyl-tRNA synthetase. - ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01876:DARS2, aspS; aspartyl-tRNA synthetase [EC:6.1.1.12] 1.0 none 1.0 1617364 2631191 3005218 1511846 0 2437644 0 2213254 1973109 2143168 2627676 0 3112975 0 2101164 3326849 2613025 0 0 2016543 0 2594975 0 2441242 1983922 1958486 1805159 0 2177367 2261386 2710262 2508060 2695317 0 0 1761549 1700100 2831575 2308775 2509628 2513024 2235467 0 2643237 0 2335343 2073968 2835589 2653944 0 2958732 0 2139000 2287423 2231048 0 0 1944833 0 2720503 0 2372283 2000216 2062758 1972555 0 2510692 3223782 2385036 2548552 2732710 0 0 2437930 2284476 2384982 2061944 3964268 3210361 2381162 0 2847659 0 2715216 2699606 2217080 2922285 0 3173584 0 2332013 2623405 2351639 0 0 2176369 0 2892240 0 2030250 2598640 2145821 2703843 0 2565325 2498678 2584644 3133868 2662909 0 0 2506627 2583302 2937837 2081256 2813496 2446962 1557852 0 2371715 0 2504439 2134892 2351820 2796877 0 2362878 0 2423273 2997633 2150131 0 0 1899218 0 2240995 0 1540107 2234812 2152990 2011331 0 2697165 2082859 512602 2732773 2875241 0 0 2177430 1788486 3439199 2225535 2972714 2407086 3759940 0 3455464 0 2757109 2670864 3218716 2471484 0 3930632 0 2606394 3232482 2865977 0 0 2769652 0 2552970 0 3470015 2426046 2448210 1997413 0 4057610 3078813 3358009 4207400 3469050 0 0 2595633 2299330 2967495 +(Pyro-carbamidomethyl)CFYALEQER MGYG000002438_03723;MGYG000000243_01720;MGYG000002478_03979;MGYG000004797_04027 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1155@1|root,COG1155@2|Bacteria,4NIB6@976|Bacteroidetes,2FMQ6@200643|Bacteroidia,4AM1M@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit 1.0 atpA 1.0 - 1.0 3.6.3.14,3.6.3.15 1.0 ko:K02117 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03723 0.25 H(+)-transporting two-sector ATPase. | Na(+)-transporting two-sector ATPase. mitochondrial ATPase. | sodium-transporting two-sector ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. | A multisubunit ATPase transporter found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis.-!-The enzyme is similar to EC 7.1.2.2 but pumps Na(+) rather than H(+). cf. EC 7.2.2.3 and EC 7.2.2.4.-!-Formerly EC 3.6.3.15. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. | ATP + H2O + 4 Na(+)(in) = ADP + H(+) + 4 Na(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways 1.0 K02117:ATPVA, ntpA, atpA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 705015 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CFYALSQGR MGYG000000074_00959 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1155@1|root,COG1155@2|Bacteria,4NIB6@976|Bacteroidetes,2FMQ6@200643|Bacteroidia,22TZV@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit 1.0 atpA 1.0 - 1.0 3.6.3.14,3.6.3.15 1.0 ko:K02117 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00959 1.0 H(+)-transporting two-sector ATPase. | Na(+)-transporting two-sector ATPase. mitochondrial ATPase. | sodium-transporting two-sector ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. | A multisubunit ATPase transporter found in some halophilic or alkalophilic bacteria that functions in maintaining sodium homeostasis.-!-The enzyme is similar to EC 7.1.2.2 but pumps Na(+) rather than H(+). cf. EC 7.2.2.3 and EC 7.2.2.4.-!-Formerly EC 3.6.3.15. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. | ATP + H2O + 4 Na(+)(in) = ADP + H(+) + 4 Na(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways 1.0 K02117:ATPVA, ntpA, atpA; V/A-type H+/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 130113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGALMMPHR MGYG000001065_00261;MGYG000002945_00023;MGYG000000179_02817;MGYG000002286_00299;MGYG000003012_02436;MGYG000000123_04491;MGYG000000184_01513;MGYG000004296_02221;MGYG000003684_03684;MGYG000001564_03631;MGYG000000205_02427;MGYG000002528_02347;MGYG000000356_00278;MGYG000000133_02978;MGYG000004884_01461;MGYG000000251_02472;MGYG000002247_00696;MGYG000000139_01214;MGYG000001531_02457;MGYG000000198_02838;MGYG000003074_00675;MGYG000004630_02620;MGYG000000152_04139;MGYG000000187_01105;MGYG000003425_04033;MGYG000000087_01701;MGYG000000233_01459;MGYG000002756_00452;MGYG000001619_01623;MGYG000002276_00117;MGYG000003821_02212;MGYG000001367_03878;MGYG000004691_02181;MGYG000001617_02721;MGYG000000050_00499;MGYG000000172_00225;MGYG000000217_03235;MGYG000004747_02388;MGYG000004879_01707;MGYG000000201_02958;MGYG000001689_01909;MGYG000000255_00182;MGYG000000806_01709;MGYG000002835_01149;MGYG000002212_02575;MGYG000002985_01348;MGYG000000193_02646;MGYG000000216_01771;MGYG000001602_00675;MGYG000002170_00636;MGYG000001493_00603 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,3Y029@572511|Blautia 0.45098039215686275 186801|Clostridia 1.0 S 0.8627450980392157 Psort location Cytoplasmic, score 8.87 0.45098039215686275 - 0.8627450980392157 - 1.0 - 1.0 ko:K07040 0.8627450980392157 - 0.8627450980392157 - 0.8627450980392157 - 1.0 - 1.0 ko00000 0.8627450980392157 - 1.0 - 1.0 - 1.0 DUF177 0.8627450980392157 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001065_00261 0.0196078431372549 - - - - 1.0 1.0 1.0 1.0 - 0.8627450980392157 K07040:yceD, ylbN; DUF177 domain-containing protein 0.8627450980392157 none 1.0 840183 560100 655839 0 0 1168097 0 872274 625837 1054683 1002503 936610 969649 925207 1051760 726772 275403 0 947852 906193 980288 1181443 0 920386 1024314 685423 771394 0 1291700 798932 217635 564657 475588 0 0 829202 699032 495486 1834799 1619807 1555153 0 0 1567327 0 1578274 1160102 1646703 1432098 1866560 1667624 1395810 1281426 1302146 1337429 0 1256536 1601137 1471834 1297778 0 1344605 1409472 1168717 1587812 0 2090073 1619090 1722690 1521635 1636364 0 0 1444611 1139986 1266581 990736 1369391 1055232 0 0 1292968 0 1042129 995453 1081378 962169 1457612 1305460 1225174 1035421 1040312 1206248 0 1098858 983793 981742 2365438 0 1114780 768978 1026760 1201833 0 1684764 1028054 1092737 1352544 1048077 0 0 1123755 1013495 958791 402736 760758 471174 0 0 353863 0 453752 422922 687736 466115 462965 782037 417025 537665 477036 638132 0 359968 429705 796415 451884 0 432436 442786 346230 432946 0 906565 533147 692960 921122 604467 0 0 444086 481036 337719 5735752 3656561 4085792 0 0 3570360 0 3994726 4129521 5520621 3159946 3595560 3145279 5667120 4430668 2867427 4682853 0 4320130 3168898 5862211 4896083 0 4875913 4550957 3917853 5814053 0 8361624 2445769 3823354 4489086 6417521 0 0 4770239 3711275 3647466 +(Pyro-carbamidomethyl)CGANKDTR MGYG000003535_01089;MGYG000001733_01436;MGYG000003425_04059;MGYG000000179_01927;MGYG000003353_02290;MGYG000001615_04787;MGYG000001164_02313;MGYG000000150_00934;MGYG000004296_01453;MGYG000001643_01060;MGYG000000184_00227;MGYG000004495_01226;MGYG000000146_00711;MGYG000000242_01153;MGYG000000258_01582;MGYG000003697_01524;MGYG000001065_01729;MGYG000000193_03368;MGYG000001315_01422;MGYG000000084_02464;MGYG000000142_01678;MGYG000001300_02311;MGYG000000201_03541;MGYG000002492_01827;MGYG000000249_00741;MGYG000000255_01277;MGYG000000233_02484;MGYG000004740_01746;MGYG000000198_03217;MGYG000002517_01999;MGYG000003694_01770;MGYG000000182_00198;MGYG000002641_01086;MGYG000002293_02312;MGYG000000489_00960;MGYG000002274_02526;MGYG000001637_01423;MGYG000000251_02509;MGYG000000154_00030;MGYG000003937_01472;MGYG000004638_00366;MGYG000001338_02508;MGYG000002721_02375 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia 0.5116279069767442 186801|Clostridia 0.813953488372093 H 0.9534883720930233 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 0.8372093023255814 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003535_01089 0.023255813953488372 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 272478 83953 276500 0 0 0 0 0 0 0 0 0 0 0 0 306314 216058 503550 0 0 0 0 431634 0 0 364517 0 462980 0 229101 0 186942 163037 0 215190 0 145838 0 256732 221858 292589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358897 0 0 0 0 257115 0 0 226051 0 462402 0 276732 377794 167039 176278 0 119482 0 153946 0 508921 810135 640231 0 0 0 0 0 0 0 0 0 0 0 0 515049 283380 161203 0 0 0 0 317103 0 0 566797 0 377349 0 451413 268055 430996 739660 0 395589 0 580006 660893 835521 1406994 1242635 0 0 0 0 0 0 0 0 0 0 0 0 992807 1201708 1185643 0 0 0 0 367405 0 0 1248395 0 1837913 0 966110 1422110 1069543 981912 0 1076928 0 891270 1259848 78716 0 189954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25626 0 0 116324 0 0 0 0 163660 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGASHGC(Carbamidomethyl)APIPEEGK MGYG000000223_01509 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,3VSKI@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 NifU-like N terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_01509 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1410141 0 0 0 0 0 0 0 1277331 2661904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1488584 0 0 0 0 0 0 0 699368 1945339 0 685591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203557 0 0 0 0 0 0 0 182944 0 0 2132293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGASHGC(Carbamidomethyl)APIPEEGKWVYSR MGYG000000223_01509 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,3VSKI@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 NifU-like N terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_01509 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1377293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGATYHLVYAAPK MGYG000000133_00066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3XZAB@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism 1.0 adk 1.0 - 1.0 2.7.4.3 1.0 ko:K00939 1.0 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 1.0 M00049 1.0 R00127,R01547,R11319 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS20110 1.0 ADK,ADK_lid 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00066 1.0 adenylate kinase. myokinase. Inorganic triphosphate can also act as donor. AMP + ATP = 2 ADP. 1.0 1.0 1.0 1.0 Purine metabolism|Thiamine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00939:adk, AK; adenylate kinase [EC:2.7.4.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 966771 0 0 0 0 0 0 0 0 0 0 0 479492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 529197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2517452 0 0 0 0 0 0 0 0 0 0 0 2498310 0 0 0 0 3681308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGDTVC(Carbamidomethyl)VVK MGYG000000179_04898 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,269AQ@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 P 1.0 FeoA 1.0 feoA 1.0 - 1.0 - 1.0 ko:K04758 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 - 1.0 - 1.0 - 1.0 FeoA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_04898 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04758:feoA; ferrous iron transport protein A 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1246885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGEDLNYAR MGYG000002477_02766;MGYG000002506_01246;MGYG000002494_03422;MGYG000002535_02468;MGYG000002534_02969;MGYG000002500_02895;MGYG000003372_02436 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,3XPGP@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Belongs to the pyruvate kinase family 1.0 pykA 1.0 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 2.7.1.40 1.0 ko:K00873 1.0 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050 1.0 R00200,R00430,R01138,R01858,R02320 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 e_coli_core.b1854,iAF1260.b1854,iB21_1397.B21_01813,iBWG_1329.BWG_1668,iEC042_1314.EC042_2021,iECBD_1354.ECBD_1784,iECB_1328.ECB_01825,iECDH10B_1368.ECDH10B_1995,iECDH1ME8569_1439.ECDH1ME8569_1801,iECD_1391.ECD_01825,iECO103_1326.ECO103_2044,iECO111_1330.ECO111_2362,iECO26_1355.ECO26_2692,iECUMN_1333.ECUMN_2152,iETEC_1333.ETEC_1887,iEcDH1_1363.EcDH1_1786,iEcE24377_1341.EcE24377A_2084,iEcHS_1320.EcHS_A1947,iEcSMS35_1347.EcSMS35_1332,iEcolC_1368.EcolC_1778,iG2583_1286.G2583_2306,iJO1366.b1854,iJR904.b1854,iSBO_1134.SBO_1162,iSSON_1240.SSON_1294,iSbBS512_1146.SbBS512_E2130,iUMNK88_1353.UMNK88_2326,iY75_1357.Y75_RS09740 1.0 PK,PK_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002477_02766 0.14285714285714285 pyruvate kinase. phosphoenol transphosphorylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Purine metabolism|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|Glucagon signaling pathway|Type II diabetes mellitus|Human papillomavirus infection|Viral carcinogenesis|Central carbon metabolism in cancer 1.0 K00873:PK, pyk; pyruvate kinase [EC:2.7.1.40] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 794184 0 0 0 0 0 0 798512 0 0 0 0 0 380544 0 0 0 0 795059 0 0 0 0 0 0 0 0 0 0 0 776052 0 0 0 0 567198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGELALLR MGYG000002494_01481 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,3XP3E@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation 1.0 metE 1.0 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.1.1.14 1.0 ko:K00549 1.0 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 1.0 M00017 1.0 R04405,R09365 1.0 RC00035,RC00113,RC01241 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 1.0 Meth_synt_1,Meth_synt_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01481 1.0 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. tetrahydropteroylglutamate-homocysteine transmethylase. Requires phosphate.-!-The enzyme from Escherichia coli also requires a reducing system.-!-Unlike EC 2.1.1.13 this enzyme does not contain cobalamin. 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Selenocompound metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00549:metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234691 0 0 0 0 0 125319 0 0 0 0 0 0 203610 85528 0 248733 0 218251 181582 0 111069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGELGTVHR MGYG000002485_02237 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0441@1|root,COG0441@2|Bacteria,378FC@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000002485_02237 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01868:TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92553 0 0 0 0 0 0 0 0 0 234929 0 0 0 0 0 0 0 0 1457414 0 0 1714430 0 0 0 1388385 1134327 0 0 0 0 1592886 0 0 0 0 0 1761592 0 1309506 0 0 0 0 0 0 0 970993 1565744 0 0 0 0 1226402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGELM(Oxidation)M(Oxidation)PHR MGYG000000967_00086;MGYG000004781_02148;MGYG000000389_00417;MGYG000001637_01679;MGYG000003828_01159;MGYG000000404_01424;MGYG000002517_01945;MGYG000004891_01821;MGYG000002963_01649;MGYG000004271_01619;MGYG000002131_00197;MGYG000004634_01055;MGYG000000127_02821;MGYG000000271_00778;MGYG000002145_00129;MGYG000000997_00132;MGYG000004210_01966;MGYG000004719_01295;MGYG000001303_02393;MGYG000001683_00880;MGYG000000136_01418;MGYG000002492_01354;MGYG000000245_01688;MGYG000000378_01329;MGYG000001793_00084;MGYG000002974_00298;MGYG000000989_00458;MGYG000002670_00826;MGYG000001027_01111;MGYG000004558_02523;MGYG000001186_01940;MGYG000000489_00567;MGYG000001652_01105 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia 0.45454545454545453 186801|Clostridia 1.0 S 0.7272727272727273 acr, cog1399 0.45454545454545453 - 0.7272727272727273 - 1.0 - 1.0 ko:K07040 0.7272727272727273 - 0.7272727272727273 - 0.7272727272727273 - 1.0 - 1.0 ko00000 0.7272727272727273 - 1.0 - 1.0 - 1.0 DUF177 0.7272727272727273 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000967_00086 0.030303030303030304 - - - - 1.0 1.0 1.0 1.0 - 0.7272727272727273 K07040:yceD, ylbN; DUF177 domain-containing protein 0.7272727272727273 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGELMMPHR MGYG000000967_00086;MGYG000004781_02148;MGYG000000389_00417;MGYG000001637_01679;MGYG000003828_01159;MGYG000000404_01424;MGYG000002517_01945;MGYG000004891_01821;MGYG000002963_01649;MGYG000004271_01619;MGYG000002131_00197;MGYG000004634_01055;MGYG000000127_02821;MGYG000000271_00778;MGYG000002145_00129;MGYG000000997_00132;MGYG000004210_01966;MGYG000004719_01295;MGYG000001303_02393;MGYG000001683_00880;MGYG000000136_01418;MGYG000002492_01354;MGYG000000245_01688;MGYG000000378_01329;MGYG000001793_00084;MGYG000002974_00298;MGYG000000989_00458;MGYG000002670_00826;MGYG000001027_01111;MGYG000004558_02523;MGYG000001186_01940;MGYG000000489_00567;MGYG000001652_01105 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia 0.45454545454545453 186801|Clostridia 1.0 S 0.7272727272727273 acr, cog1399 0.45454545454545453 - 0.7272727272727273 - 1.0 - 1.0 ko:K07040 0.7272727272727273 - 0.7272727272727273 - 0.7272727272727273 - 1.0 - 1.0 ko00000 0.7272727272727273 - 1.0 - 1.0 - 1.0 DUF177 0.7272727272727273 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000967_00086 0.030303030303030304 - - - - 1.0 1.0 1.0 1.0 - 0.7272727272727273 K07040:yceD, ylbN; DUF177 domain-containing protein 0.7272727272727273 none 1.0 1676552 1704581 1081218 1271995 0 1552208 0 1683851 1496021 1380665 2182834 0 0 0 0 1585799 1402088 456349 1300994 1727615 0 1672520 406726 1422792 1981900 1423374 1532705 747012 0 1677333 758880 0 1005738 1671052 1436570 1418100 1543904 1089573 1577319 3812748 1893063 2133222 0 995924 0 1497731 1367748 1521939 1553679 0 0 0 0 999252 1924179 2825267 1432982 1707781 0 715906 2415578 1525343 1271748 1318115 1575687 2554415 0 1276917 3636778 0 1671414 1554792 1628963 1721445 1190786 1380569 1226802 2015591 1784688 723812 0 551708 0 1019624 931538 858391 980766 0 0 0 0 1706624 950170 743381 1282432 1178025 0 864512 915055 272719 1495425 1193507 1242929 1122476 0 1052377 963701 0 1694191 1069023 1270148 1261305 914524 1710878 2612562 2525880 1325019 2742950 0 1082201 0 3258142 3474596 1585662 1728262 0 0 0 0 1788223 2365280 348851 2467899 2715807 0 0 0 631459 3859541 3498234 3379119 0 0 2611393 2809815 0 1550466 2330261 3138413 3423526 3724776 1377717 3552645 3548923 3432341 499464 0 3001147 0 2527429 3490681 4292404 2147940 0 0 0 0 2720427 3529146 889586 4209127 3058251 0 2686134 1170847 1949057 3937548 3346109 2879396 1393512 0 3301809 4313750 0 3607851 4567527 3319008 3155494 4199462 3919278 +(Pyro-carbamidomethyl)CGEWHVYHTVC(Carbamidomethyl)GAC(Carbamidomethyl)GYYR MGYG000000243_00707;MGYG000001378_03243;MGYG000001661_02741;MGYG000000042_00685;MGYG000000236_02794;MGYG000003367_02448;MGYG000002478_00477;MGYG000004479_01738;MGYG000004797_02847;MGYG000000013_03200;MGYG000003351_01374;MGYG000000196_04043;MGYG000004899_04076;MGYG000001780_04486;MGYG000002455_03824;MGYG000000781_00308;MGYG000000273_02620;MGYG000001337_04283;MGYG000000098_03799;MGYG000003363_02244 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0333@1|root,COG0333@2|Bacteria,4NUXU@976|Bacteroidetes,2FUZD@200643|Bacteroidia,4ARR4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL32 family 1.0 rpmF 1.0 - 1.0 - 1.0 ko:K02911 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L32p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00707 0.05 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02911:RP-L32, MRPL32, rpmF; large subunit ribosomal protein L32 1.0 none 1.0 0 0 1097514 0 0 1014377 0 0 839615 0 0 0 1549145 0 0 1051702 1075273 0 0 0 0 980050 897649 1135208 0 0 1364675 966307 0 0 0 0 1100289 908249 1166885 1443689 0 661552 0 0 2568326 0 0 1547478 0 0 2293118 0 0 0 2216802 0 0 2767140 1908919 2304501 0 0 0 2515537 2737979 1746886 0 0 2306777 2217683 0 0 0 0 1857832 1847130 1742466 1519051 0 1677153 0 0 481999 0 0 653381 0 0 350160 0 0 0 299745 0 0 603164 387098 678541 0 0 0 314644 563663 286119 0 0 537330 772675 0 0 0 0 0 0 297822 273493 0 463071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527315 0 318648 0 0 0 0 670048 0 0 1017011 0 0 1455511 0 0 0 403019 0 0 371547 1021249 1938749 0 0 0 874408 1456132 1089190 0 0 774352 1870907 0 0 0 0 495277 1836135 1108955 1095048 0 1098376 +(Pyro-carbamidomethyl)CGGDHADSGK MGYG000002517_00256 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00256 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGGDHADSGKEIPIVATDGVR MGYG000002517_00256 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00256 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 848704 296922 509617 1601179 547515 473363 274956 1368982 985765 2123548 341008 413178 0 1161973 1868609 361996 727367 0 1603767 1354833 1492690 670380 0 248011 1695492 1246301 949101 0 0 470108 0 0 269509 876516 822885 1017111 917800 370210 0 0 264369 0 0 300428 0 0 0 311111 0 0 0 0 0 0 0 0 0 0 212259 368503 0 0 274111 0 0 0 0 0 0 0 0 0 0 0 268938 0 1387846 0 0 670386 0 0 0 794448 0 1197580 0 0 0 1024071 1145198 0 0 0 1244100 809351 0 0 0 0 1450459 1401773 1056900 0 0 0 0 0 0 357376 1666011 0 1536986 0 9564935 1108604 2668675 8165480 3873795 3058544 6478025 12727599 14923942 4484058 2949554 4325300 0 11414049 13225880 3900083 6809749 0 12417316 12731949 6060314 878335 0 610887 9802201 10260816 10261155 0 2456668 7052769 1903387 3534031 2106656 7680084 11153461 8845788 14158206 2939085 5965843 3821019 7461683 0 3759013 5450722 8787633 5895696 9794739 9801850 5521645 6854311 0 11501585 9428590 4173866 9382918 0 7803856 6149679 5930628 3849302 0 8454675 12653194 8098239 8398975 0 2391172 4241206 6059565 673088 6356192 8801199 8973210 12474999 12659142 8198273 +(Pyro-carbamidomethyl)CGIC(Carbamidomethyl)GEHGGEPSSVK MGYG000000236_00181;MGYG000001378_01176;MGYG000001489_03803;MGYG000000013_03892;MGYG000001461_02244;MGYG000000222_00273;MGYG000003374_01797;MGYG000002560_01450;MGYG000001780_04079;MGYG000002478_03849;MGYG000001313_01473;MGYG000003681_00659;MGYG000002455_03526;MGYG000000243_00277;MGYG000001789_01569;MGYG000004797_01193;MGYG000001306_00064;MGYG000001787_02320;MGYG000000098_03346;MGYG000001345_02795;MGYG000002438_03578;MGYG000002133_02142;MGYG000002933_01184;MGYG000000196_02017;MGYG000001661_00974;MGYG000000696_02522;MGYG000002549_01561;MGYG000003812_01931;MGYG000003363_02147;MGYG000001346_03147;MGYG000003542_00399;MGYG000003312_03561;MGYG000002218_01508;MGYG000000174_00191;MGYG000004763_00142 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 0.8285714285714286 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000236_00181 0.02857142857142857 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 2820306 0 0 0 3795976 0 0 0 0 0 0 0 0 0 0 4849027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2934423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3703456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGIVGAIAQR MGYG000002515_03899;MGYG000002494_02401;MGYG000002506_03399;MGYG000002534_04900 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0449@1|root,COG0449@2|Bacteria,1MW4K@1224|Proteobacteria,1RMVN@1236|Gammaproteobacteria,3XMF7@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 M 1.0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source 1.0 glmS 1.0 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 2.6.1.16 1.0 ko:K00820 1.0 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 1.0 - 1.0 R00768 1.0 RC00010,RC00163,RC02752 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 iE2348C_1286.E2348C_4039,iEC042_1314.EC042_4115,iECIAI39_1322.ECIAI39_4333,iECNA114_1301.ECNA114_3878,iECOK1_1307.ECOK1_4178,iECSF_1327.ECSF_3577,iECUMN_1333.ECUMN_4259,iEcSMS35_1347.EcSMS35_4097,iLF82_1304.LF82_0844,iNRG857_1313.NRG857_18570,iSFV_1184.SFV_3755,iSF_1195.SF3809,iSFxv_1172.SFxv_4151,iS_1188.S3959,iUMN146_1321.UM146_18835,iUTI89_1310.UTI89_C4281 1.0 GATase_6,GATase_7,SIS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_03899 0.25 glutamine--fructose-6-phosphate transaminase (isomerizing). L-glutamine-D-fructose-6-phosphate amidotransferase. Although the overall reaction is that of a transferase, the mechanism involves the formation of ketimine between fructose 6-phosphate and a 6-amino group from a lysine residue at the active site, which is subsequently displaced by ammonia (transamidination).-!-Formerly EC 5.3.1.19. D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Insulin resistance 1.0 K00820:glmS, GFPT; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16] 1.0 none 1.0 0 0 365857 690740 0 798802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788629 0 693394 0 0 0 0 0 0 0 0 290470 0 0 0 0 397716 0 0 523204 701727 0 640820 0 0 0 0 0 0 0 0 0 0 457822 0 0 0 0 742203 0 573421 0 0 0 0 0 0 0 0 379422 0 0 0 0 381703 0 0 0 357922 0 0 0 0 0 0 0 0 0 0 0 0 156487 0 0 0 0 164806 0 189552 0 0 0 0 0 0 0 0 0 0 0 0 0 226803 0 0 509473 206335 0 436351 0 0 0 0 0 0 0 0 0 0 208976 0 0 0 0 436292 0 379362 0 0 0 0 0 0 0 0 378820 0 0 0 0 469057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGKEVEVFTSR MGYG000000133_01803;MGYG000000301_00524 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 2A2DC@1|root,30QQD@2|Bacteria,1UGEZ@1239|Firmicutes,25NVE@186801|Clostridia,3Y22X@572511|Blautia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01803 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 466400 0 0 175463 0 0 0 0 0 452843 724957 0 0 0 0 0 0 0 0 0 0 253112 0 288000 0 380299 0 0 0 0 0 0 0 0 0 0 400678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 875126 0 835927 1714595 0 1139648 0 0 0 1412992 1047461 0 1452749 0 0 0 1321040 0 0 0 0 0 0 382435 0 983391 0 0 1437829 613731 1126930 0 910468 0 0 0 1534545 838840 +(Pyro-carbamidomethyl)CGLC(Carbamidomethyl)AEKC(Carbamidomethyl)PK MGYG000000271_00487;MGYG000004271_01086 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1036@1|root,COG2878@1|root,COG1036@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transport complex, RnfABCDGE type, B subunit 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_13,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00487 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03616:rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGLSEHFK MGYG000001689_04266;MGYG000003012_02006;MGYG000000806_00468;MGYG000003821_00299 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3XZ3D@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 ldh 1.0 - 1.0 1.1.1.27 1.0 ko:K00016 1.0 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 1.0 - 1.0 R00703,R01000,R03104 1.0 RC00031,RC00044 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Ldh_1_C,Ldh_1_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001689_04266 0.25 L-lactate dehydrogenase. L-lactic dehydrogenase. Also oxidizes other (S)-2-hydroxymonocarboxylic acids.-!-NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme. (S)-lactate + NAD(+) = H(+) + NADH + pyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Cysteine and methionine metabolism|Pyruvate metabolism|Propanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Glucagon signaling pathway 1.0 K00016:LDH, ldh; L-lactate dehydrogenase [EC:1.1.1.27] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1000723 0 0 1970407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2391326 0 2716449 0 0 0 0 0 0 0 0 2008999 0 0 0 0 793524 +(Pyro-carbamidomethyl)CGMFYVNER MGYG000004719_00253;MGYG000000067_03067;MGYG000000141_02711;MGYG000001814_01311;MGYG000004735_00874;MGYG000002121_00509;MGYG000000562_00434;MGYG000000271_00181;MGYG000002563_01003;MGYG000004271_02124;MGYG000000389_00258;MGYG000002854_01839;MGYG000000164_02268;MGYG000002517_01401;MGYG000000515_00532;MGYG000004805_00611;MGYG000000187_01168;MGYG000002393_02328 domain d__Bacteria 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia 0.2777777777777778 186801|Clostridia 0.8888888888888888 J 1.0 Belongs to the universal ribosomal protein uS2 family 0.8888888888888888 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004719_00253 0.05555555555555555 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 377114 376326 311804 563758 0 458109 0 0 341979 0 0 0 0 357378 443430 316537 0 0 137758 494652 0 447243 0 250118 696325 687548 647193 0 0 647812 0 0 230865 297800 527673 512979 511542 232879 0 0 0 0 0 0 0 0 0 0 0 0 0 252796 0 0 0 0 122950 130735 0 0 0 0 0 0 0 0 0 0 0 0 0 114945 150623 0 0 0 491361 160975 137502 0 0 93125 0 0 233861 0 0 0 0 251287 446010 112832 0 0 275903 307492 0 195824 0 158806 356039 603584 118525 0 0 383291 0 0 107066 141864 410537 288865 392785 0 473137 0 151204 538085 0 143489 0 0 592078 0 0 0 0 563043 611066 182156 0 0 363045 468735 0 0 0 0 566566 494293 515011 0 0 360340 0 0 153275 342388 553295 392269 465532 0 1308332 886317 1066143 1026243 0 930771 0 0 926229 0 0 0 0 1373782 1222428 868739 0 0 938991 747106 0 813774 0 938295 1590818 1071135 1284365 0 0 790808 0 0 1186081 1151822 995470 1217169 1318612 1094289 +(Pyro-carbamidomethyl)CGMFYVNQR MGYG000000080_02857;MGYG000002528_02846 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_02857 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493891 0 0 0 392301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 936323 0 164127 0 0 0 0 517825 0 0 0 0 402181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632024 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGMHYVNAR MGYG000000022_01263;MGYG000002272_01435;MGYG000001300_00246;MGYG000002223_00595;MGYG000001627_01481;MGYG000001157_00347;MGYG000002610_00266;MGYG000004866_00093;MGYG000002545_00160;MGYG000000195_01345;MGYG000003921_00807;MGYG000002274_00630;MGYG000002651_00048;MGYG000003937_00035;MGYG000002641_00104 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01263 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 1431743 1643695 2070151 1755633 1379422 1822594 880298 1389936 1485497 1471179 1478710 1292552 2395221 1970054 1640913 1799117 1626558 2249705 1876059 1699295 1064687 1572661 2522830 1404628 1505932 1623960 1745705 2481763 1020565 1514096 1500170 1340534 1984464 1859853 1193259 1342724 1274078 1606461 2847604 1610610 2067901 2393094 1477773 2040511 2619177 1209435 2403258 773425 2322362 2622643 1911771 2319088 2277104 1541919 2674452 2517892 3463634 2046490 1093307 1191888 3262306 1633847 2694757 2146753 2232515 3309244 674581 2300166 1678722 1543345 2075913 2182733 1060324 1862913 1954957 1708451 816534 875531 897761 822580 1017813 1071608 974555 956341 980141 856684 1258813 1006663 1159866 888351 954397 938939 1018447 2314066 698344 647935 704791 712678 2009667 994386 838136 899441 611660 2714676 568245 1272596 1075890 805259 732795 966582 914201 796843 874915 832696 1051795 1138798 1666874 1193024 1208604 1388213 1430321 866358 1364219 1381823 1441233 2012384 1752692 1067858 1220451 1155519 1288698 1802794 1569752 1152500 1302378 1878813 1785121 1367823 1771093 1199846 1070199 1375520 682939 1421984 1724968 1166013 1347127 1374839 1056940 1129275 1042918 1794382 379761 465259 934750 567383 466737 435404 498138 693913 457359 487546 328315 1313455 646869 492611 303150 515443 409686 2322728 439691 260589 444345 565523 3274700 322090 514215 422135 477512 3237267 648780 502057 638262 588321 934588 541950 567787 402954 419294 698725 +(Pyro-carbamidomethyl)CGMYYVNER MGYG000000150_02990;MGYG000004747_01385;MGYG000000179_02939;MGYG000002279_01755;MGYG000000280_00470;MGYG000000255_00471;MGYG000003695_01035;MGYG000004087_03021;MGYG000000404_00635;MGYG000001315_00796;MGYG000001310_00255;MGYG000001615_00539;MGYG000000417_00486;MGYG000000909_00277;MGYG000003355_04406;MGYG000000251_01121;MGYG000000249_01234;MGYG000001645_00483;MGYG000000136_00722;MGYG000001186_00373;MGYG000004296_02310;MGYG000000146_01613;MGYG000001319_00659;MGYG000000217_03427;MGYG000000242_00797;MGYG000000312_01585;MGYG000002304_00361;MGYG000002492_01612 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,21Y04@1506553|Lachnoclostridium 0.39285714285714285 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 0.6785714285714286 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_02990 0.03571428571428571 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 759522 664625 1009501 0 753183 725779 533731 1200689 596553 763970 1007192 957536 877393 685410 1102030 656191 135851 0 664642 865880 0 798800 0 632691 1023472 809840 803746 0 811396 687778 730142 702974 783309 749313 841182 687812 711391 700335 867921 786919 1075121 0 1037429 231356 1207182 1161599 649921 1106206 1289380 909945 1350445 784255 811274 1083281 1551605 0 743526 1031098 0 536938 0 854703 1025678 868255 1094061 0 1165558 933000 970260 1097050 1265348 1060306 860968 1077682 690933 1324084 1129106 983716 2587814 0 1317269 1120494 1215993 1235487 1011804 1228190 1505493 1685771 1924625 1126491 1183927 2156757 1026573 0 1179255 1140785 0 1165083 0 1131409 1290960 1199778 1172773 0 1156007 1250589 1608136 1347316 3026691 1400020 1355320 1104520 1117618 2325129 179881 617650 527783 0 333184 290999 282958 366887 261862 419562 574658 460354 538704 291212 258217 384410 541100 0 451526 348093 0 292930 0 294017 339245 374849 324372 0 317891 416065 466439 429262 715177 263670 413997 322642 293774 703350 197952 503087 879518 0 750227 461058 543488 644741 709183 1224771 566787 701449 463902 885447 809558 652915 1029857 0 812518 822761 0 651888 0 552166 668086 1010563 1014198 0 1118780 595582 634706 494716 954950 988061 747239 848653 1009259 824670 +(Pyro-carbamidomethyl)CGNIHGANFK MGYG000000179_04478 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 299ND@1|root,2ZWQQ@2|Bacteria,1V769@1239|Firmicutes,25D2A@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 L-2-amino-thiazoline-4-carboxylic acid hydrolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ATC_hydrolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_04478 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1074346 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGQFYVNER MGYG000000201_03495;MGYG000000002_01239;MGYG000000213_00523;MGYG000000050_02653;MGYG000004785_01641;MGYG000000184_03160 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_03495 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 302186 817591 488125 0 867230 695372 0 498489 179196 427251 880409 555308 785279 227914 441713 0 368459 0 323717 0 0 831203 0 255116 509043 237120 200413 0 658083 0 395267 973057 405730 248806 0 252236 0 464680 181207 1162503 0 200210 153444 0 0 125720 0 0 178971 0 230000 0 0 0 0 0 0 0 0 0 0 171530 0 0 0 0 436314 0 1906777 486701 0 0 0 0 0 0 0 1315393 457185 0 0 0 0 226475 0 0 289097 406801 437939 210771 172915 0 295657 0 0 0 0 434860 0 0 371209 0 265688 0 345947 0 150298 1183290 369964 250479 0 0 0 356238 0 1079966 544534 0 663585 0 0 0 132273 303093 316185 217841 551626 0 0 0 124573 0 0 0 0 0 0 131083 0 0 171491 0 689280 0 1323808 746331 175497 0 0 0 0 563564 1476112 3053333 2295992 2093711 905742 1519142 2009076 1424212 1097365 1732180 1737341 1330953 1548875 2599001 1693288 0 1181929 0 1403426 0 0 1820691 0 1406985 1270355 1300547 1911711 0 2279713 0 2393067 3476352 4204231 1325891 0 1535323 1261707 1488351 +(Pyro-carbamidomethyl)CGTPLSSHEVAQGYK MGYG000000255_02938 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,21XHQ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) 1.0 ileS 1.0 - 1.0 6.1.1.5 1.0 ko:K01870 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03656 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_02938 1.0 isoleucine--tRNA ligase. isoleucyl-tRNA synthetase. - ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01870:IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830503 0 0 0 0 0 0 0 0 0 530277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGVEVGKDVTIQQLR MGYG000002517_01855 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 'glutamate synthase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4,Fer4_20,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01855 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 848135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1038727 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CGVEVTEKK MGYG000001306_02654;MGYG000004561_01031;MGYG000003493_00375;MGYG000002935_00902;MGYG000002455_03893;MGYG000001546_01550;MGYG000001378_05033;MGYG000003542_00717;MGYG000000243_01979;MGYG000001346_01525;MGYG000001415_02506;MGYG000000105_01994;MGYG000001562_01084;MGYG000001641_01493;MGYG000001313_00088;MGYG000000224_00483;MGYG000003542_00369;MGYG000000003_02519;MGYG000001345_04693;MGYG000001489_05036;MGYG000004757_00585;MGYG000004885_00605;MGYG000000053_00899;MGYG000000170_00064;MGYG000001630_01150;MGYG000000196_03983;MGYG000004720_01708;MGYG000002549_02931;MGYG000004536_01758;MGYG000000042_01430;MGYG000002478_00805;MGYG000003374_00512;MGYG000001789_00145;MGYG000001666_00329;MGYG000004797_04274;MGYG000000074_01764;MGYG000000054_03942;MGYG000003649_01855;MGYG000004105_01519;MGYG000000236_01798;MGYG000004763_01698;MGYG000004658_01196;MGYG000003681_02045;MGYG000000222_01122;MGYG000002438_02330 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 0.4666666666666667 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 0.9777777777777777 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000001306_02654 0.022222222222222223 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 821902 0 0 0 0 1077193 0 0 0 0 0 0 0 0 0 0 861532 0 671448 0 0 817598 0 988646 0 1085761 0 0 0 469678 0 0 0 0 0 0 695087 0 1937732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1259675 0 700055 0 0 1480011 0 912088 0 1430021 0 0 0 1540932 0 0 0 0 0 0 1765687 0 911693 0 0 0 0 1002388 0 0 0 0 0 0 0 0 0 0 923448 0 1075887 0 0 580829 0 922092 0 607176 0 0 0 0 0 0 0 0 0 0 1158699 0 943353 0 0 0 0 1558593 0 0 0 0 0 0 0 0 0 0 705365 0 1067235 0 0 1510035 0 0 0 1591509 0 0 0 707547 0 0 0 0 0 0 908538 0 1316886 0 0 0 0 1612838 0 0 0 0 0 0 0 0 0 0 967863 0 1475236 0 0 887236 0 969441 0 1898458 0 0 0 1929229 0 0 0 0 0 0 1572584 0 +(Pyro-carbamidomethyl)CGYWHLWR MGYG000002560_01730;MGYG000001770_00199;MGYG000003493_02131;MGYG000002561_01024;MGYG000003202_01861;MGYG000000042_02678;MGYG000003693_00676;MGYG000000413_00744;MGYG000003363_02878;MGYG000000215_00689;MGYG000002293_01557;MGYG000003470_01719;MGYG000003362_00325;MGYG000004885_01331;MGYG000000196_04414;MGYG000001789_02092;MGYG000003446_00859;MGYG000002033_00365;MGYG000000138_01901;MGYG000001780_02881;MGYG000001346_02526;MGYG000002905_00715;MGYG000003680_00979;MGYG000003221_00209;MGYG000001666_02224;MGYG000000236_00388;MGYG000000415_01202;MGYG000001643_00941;MGYG000004757_00573;MGYG000003301_00088;MGYG000001345_00428;MGYG000004569_01724;MGYG000003185_00896;MGYG000000013_01171;MGYG000002549_02787;MGYG000000781_02114;MGYG000001306_03824;MGYG000002455_00144;MGYG000002540_01631;MGYG000002108_01088;MGYG000001337_03683;MGYG000004899_00334;MGYG000003697_00534;MGYG000004474_00367;MGYG000004495_01066;MGYG000000243_00095;MGYG000001920_00369;MGYG000004479_01116;MGYG000004464_00688;MGYG000001461_03964;MGYG000000029_01835;MGYG000004876_02170;MGYG000003681_00938;MGYG000001489_04394;MGYG000000305_00576;MGYG000001630_01448;MGYG000001313_00862;MGYG000002478_04117;MGYG000001364_01848;MGYG000001763_01292;MGYG000001835_01025;MGYG000002051_02389;MGYG000002438_04196;MGYG000004763_00186 domain d__Bacteria 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 0.5625 976|Bacteroidetes 0.96875 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 0.96875 - 1.0 - 1.0 - 1.0 GT2 0.984375 MGYG000002560_01730 0.015625 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 1202221 1451740 622208 1000809 1060532 848411 890189 924911 926802 977212 2318623 842725 1268368 1700021 940645 705260 750764 0 801536 1100313 1381722 739461 0 1415344 840020 1136440 1207920 0 0 1488902 1268780 1940302 984537 1800902 0 1781638 2407198 835701 1353224 1046549 1917171 1174569 1019402 1016731 717749 1572282 0 2395644 2529048 2283105 2464792 2649403 3958632 1251912 2117146 0 1863788 1688047 2701921 1405828 0 985569 3192395 1630984 1760143 0 0 0 992026 1446881 1550478 1423821 0 1456123 2803529 2294894 0 0 2593227 386347 2541280 1466896 2025727 1197219 2218688 0 4805454 0 0 0 1814305 475371 933027 0 1452361 582329 0 0 0 2770383 2557148 0 165890 0 0 0 74734 2289617 0 68570 0 0 911727 2633972 2240777 1417088 930348 0 0 3316790 0 2647581 2831993 0 3045776 0 9967376 0 1337852 2090486 3384548 0 0 171788 6209139 80641 0 320609 4800979 0 204185 0 0 0 2634051 64974 1646829 0 0 0 0 2528661 0 105427 0 0 0 2660964 892249 0 0 0 7303 2737 0 0 0 0 0 0 3505 0 0 7890 0 3818871 0 3299999 0 0 0 0 131061 0 0 116063 0 7048 5628362 0 +(Pyro-carbamidomethyl)CGYWHNFR MGYG000002298_00647;MGYG000001602_02095;MGYG000001617_02091;MGYG000000133_02129;MGYG000000142_01058;MGYG000002445_00390;MGYG000000212_02086;MGYG000000031_03215;MGYG000000171_02087;MGYG000000002_01844;MGYG000001367_00948;MGYG000000050_02874;MGYG000004296_00115 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3XZ4K@572511|Blautia 0.5384615384615384 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002298_00647 0.07692307692307693 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 1253217 1926274 780021 0 3008911 560806 0 0 1395620 0 0 0 1041375 0 0 0 1430820 0 0 0 2404413 1237571 1073659 0 0 0 2021720 1758368 0 0 0 1565799 1140177 0 944133 0 1550642 0 479502 460701 325946 0 335616 586700 0 0 285222 0 0 0 248537 0 0 0 1051333 0 0 0 0 686491 559961 0 0 0 1084877 741076 0 0 0 405129 533642 0 421719 0 568138 0 1194362 1183231 826608 0 1092748 639377 0 0 1089610 0 0 0 916819 0 0 0 315391 0 0 0 1759846 762624 865293 0 0 0 1049167 1017013 0 0 0 1429534 1068695 0 859748 0 1371214 0 1304114 668246 384303 0 536812 497328 0 0 697322 0 0 0 429995 0 0 0 487010 0 0 0 573172 278469 603758 0 0 0 885532 1737624 0 0 0 842560 269411 0 437541 0 935482 0 3984512 4085866 6729003 0 3161903 4462991 0 0 6188425 0 0 0 6440181 0 0 0 476022 0 0 0 3990217 1101127 3141823 0 0 0 1128226 6146923 0 0 0 6706467 4604260 0 3895681 0 4329110 +(Pyro-carbamidomethyl)CHDVNQTIIAFVNK MGYG000002517_01665 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002517_01665 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 225779 0 0 0 0 0 0 0 0 0 0 0 0 0 427734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248174 0 0 0 0 0 0 394948 0 0 0 0 0 0 238608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498320 0 0 0 0 0 0 598116 0 0 0 0 0 0 555962 0 0 0 0 0 0 0 0 0 0 604708 0 0 0 0 0 0 0 0 0 0 594990 0 1046779 0 0 0 0 0 0 714915 0 0 0 0 0 0 1493172 0 0 0 0 0 0 0 0 0 0 1233608 0 0 0 0 0 0 0 0 0 0 1043086 0 +(Pyro-carbamidomethyl)CHEHINNVLAIPGNK MGYG000002438_03452 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,22VW2@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 hydrolase activity, acting on glycosyl bonds 1.0 nagA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,TAT_signal 1.0 3.2.1.49 1.0 GH109 1.0 GH109 1.0 GH109 1.0 MGYG000002438_03452 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 540228 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CHLEDITR MGYG000000154_00552;MGYG000002517_01550 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the alpha-IPM synthase homocitrate synthase family 1.0 - 1.0 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 iHN637.CLJU_RS03250 1.0 HMGL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000154_00552 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 532051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CHNPAYIHMGMK MGYG000001627_00502;MGYG000000573_01090;MGYG000000084_00490;MGYG000001300_01192;MGYG000003166_00684 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001627_00502 0.2 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 357218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168819 0 0 0 0 106484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 837989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1030609 0 672391 0 0 0 0 990952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 68436 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CHNPSYVTK MGYG000002517_00959;MGYG000000389_00578;MGYG000004475_00979;MGYG000000154_00174;MGYG000004487_00003 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 0.6 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002517_00959 0.2 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 185734 0 0 0 0 0 0 0 0 0 258150 0 0 0 0 0 0 0 0 0 0 596151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3033350 0 0 0 0 0 0 0 0 0 3415299 0 0 0 0 0 0 0 0 0 0 2987962 0 3289716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CHPFFTGK MGYG000002944_01662;MGYG000003241_01136;MGYG000004482_01642;MGYG000002098_01144;MGYG000000412_00435;MGYG000000258_00827;MGYG000002095_00519;MGYG000003819_01132;MGYG000002926_00350;MGYG000003116_02088;MGYG000001911_00529;MGYG000004779_01763;MGYG000000358_01112;MGYG000003494_00340;MGYG000000377_00044;MGYG000004487_01757;MGYG000004734_00288;MGYG000002287_01308;MGYG000003581_01223;MGYG000003538_00848;MGYG000002720_00511;MGYG000003589_02457;MGYG000003549_00736;MGYG000002506_03634;MGYG000001732_01677;MGYG000003621_00559;MGYG000004221_00006;MGYG000003142_02526;MGYG000002323_04044;MGYG000003428_00399;MGYG000001685_00344;MGYG000002996_01085;MGYG000003484_01382;MGYG000002794_00382;MGYG000003582_00806;MGYG000002057_00277;MGYG000002934_01800;MGYG000002515_03711;MGYG000000371_00886;MGYG000003311_01734;MGYG000000392_00573;MGYG000001502_01406;MGYG000004475_00421;MGYG000004517_00716;MGYG000004743_00460;MGYG000002156_00083;MGYG000000836_00997 domain d__Bacteria 1.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,269AE@186813|unclassified Clostridiales 0.23404255319148937 186801|Clostridia 0.6595744680851063 J 1.0 Binds the 23S rRNA 0.48936170212765956 rpmE 0.9148936170212766 - 0.8297872340425532 - 0.9148936170212766 ko:K02909 0.9148936170212766 ko03010,map03010 0.9148936170212766 M00178 0.9148936170212766 - 0.9148936170212766 - 0.9148936170212766 br01610,ko00000,ko00001,ko00002,ko03011 0.9148936170212766 - 1.0 - 1.0 - 1.0 Ribosomal_L31 0.9148936170212766 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002944_01662 0.02127659574468085 - - - - 0.9148936170212766 0.9148936170212766 0.9148936170212766 0.9148936170212766 Ribosome 0.9148936170212766 K02909:RP-L31, rpmE; large subunit ribosomal protein L31 0.9148936170212766 none 1.0 1773738 1762884 1878015 0 1586957 2626323 1992515 2185593 1666156 2177648 990780 0 1224644 2681279 1908091 1375537 2493483 1112712 1723488 1871379 1957792 3066299 1145410 129690 1848217 2171606 1746655 1125764 0 1519470 1798149 2202690 1775042 2363422 2444629 2020964 1917756 1684173 1318013 1068945 1452279 0 1035086 1496894 1141297 1676790 1505763 1682696 1292561 0 1146917 1253033 1479709 1117092 1036430 508685 1512991 1206055 1164437 1510801 526677 1290478 1018052 1291422 1343217 569278 0 1054541 739102 1124044 1305878 1330204 1742178 1387053 1369387 1404016 2013926 1856136 2639855 0 2546533 3998053 2361449 2507603 2453624 2298092 2258907 0 2548733 2462616 2181487 2299107 2033693 2175193 2234669 2273512 2117419 2681302 1658883 3055840 2534850 2321498 2330849 1613410 0 2005594 2937654 1782299 1801294 2433825 2615879 2678431 2407523 1949745 2326545 2416206 2231663 0 1871743 2700960 2606359 3055751 2340014 3466913 1972150 0 2849561 1947774 2294574 2276257 2235031 1336468 2444934 1870260 2190792 2578569 1606323 2048805 3026538 2942581 2600129 911250 0 2138839 1576492 2558610 2401561 3985765 3302087 3079070 2812478 1651693 0 340222 778507 0 0 783864 699720 925165 690221 657373 573015 0 739675 570668 644652 511966 1074840 1146916 898275 0 685383 739188 1235884 1201214 713902 683181 599013 1111303 0 597010 612946 248063 467872 1090100 1164057 582402 640175 682326 +(Pyro-carbamidomethyl)CHPFYTGK MGYG000003683_00994;MGYG000001292_00592;MGYG000001300_00389;MGYG000002105_00013;MGYG000003891_02556;MGYG000004702_00491;MGYG000002223_00333;MGYG000000708_00823;MGYG000001485_00826;MGYG000002059_00084;MGYG000002494_01915;MGYG000004565_01425;MGYG000004834_02241;MGYG000004866_01409;MGYG000003408_00608;MGYG000002139_00894;MGYG000000073_00598;MGYG000001483_02679;MGYG000002854_00783;MGYG000001627_01530;MGYG000002370_03761;MGYG000000953_01713;MGYG000001424_00163;MGYG000000427_01317;MGYG000004201_01078;MGYG000004564_00748;MGYG000002040_00344;MGYG000002485_02213;MGYG000000045_02320;MGYG000003166_00009;MGYG000001779_00921;MGYG000002651_01024;MGYG000003452_00770;MGYG000002395_00480;MGYG000002224_00322;MGYG000001279_02159;MGYG000002802_00949;MGYG000000573_00476;MGYG000003465_00870;MGYG000002274_00606;MGYG000002469_01597;MGYG000000022_01287;MGYG000004707_01413;MGYG000003921_01139;MGYG000001440_01124;MGYG000001490_00439;MGYG000001480_01524;MGYG000003387_02745;MGYG000002993_01881;MGYG000002045_01614;MGYG000001136_00960;MGYG000003450_00029;MGYG000003313_00119;MGYG000000435_01031;MGYG000000479_01462;MGYG000001157_01667;MGYG000001624_00848;MGYG000000636_01561;MGYG000000303_01723;MGYG000001448_01935;MGYG000001601_01455;MGYG000002753_00307;MGYG000001563_00283;MGYG000000989_02899 domain d__Bacteria 1.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3WKI1@541000|Ruminococcaceae 0.296875 186801|Clostridia 0.515625 J 0.953125 Binds the 23S rRNA 0.734375 rpmE 0.953125 - 0.765625 - 1.0 ko:K02909 0.953125 ko03010,map03010 0.953125 M00178 0.953125 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.953125 - 0.96875 - 1.0 - 1.0 Ribosomal_L31 0.9375 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00994 0.015625 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.953125 K02909:RP-L31, rpmE; large subunit ribosomal protein L31 0.953125 none 1.0 1668498 1740259 2291431 2378427 1203829 1557680 1255257 1482058 1656353 1723669 1258946 1438647 0 2407677 1537666 2264174 1973925 3420559 2145107 1707448 1095866 1581666 3384382 1989593 1639855 1941710 1713624 3880104 819552 913618 1629027 1714871 2318817 2715989 1376802 1662268 1660666 1962314 6114023 5975688 7119780 5598918 4519727 7987766 6399001 4144918 7101795 6194383 5644205 6401141 0 5843037 5533088 5139248 7294093 2966774 7604763 4895073 4811489 6767678 4656445 6218745 7795342 5757986 5512651 4529855 4282091 6740824 3967072 4581861 6862741 5444113 3696700 4648337 5287226 5991344 921460 1098453 1068802 1189681 1342306 1272726 1176231 1052471 1113994 645604 1693877 1403128 0 1048600 905467 1393457 872148 3036235 789378 800715 911522 1251902 2376522 979670 1212403 1060582 991774 2896535 860076 1050324 1362136 946729 0 1196770 1033730 1223004 1098681 0 2002787 1510377 2631071 2209871 1966822 2250477 3150384 2086959 2587734 2366916 1980620 3477778 0 2087730 2441080 1766883 1837116 1912224 2746551 1935974 1906731 2380083 2345893 1646495 3566710 3041580 2141329 1591699 1309099 3122170 1925711 2204359 2080870 3997812 1552066 2871141 2496908 1938573 614087 566076 708213 659669 754847 675682 621874 927603 722652 666499 409672 1657421 0 563041 553767 639915 768533 6093430 648058 813101 628012 610551 6091477 654135 893217 756757 591261 5405407 853999 1011395 840898 656838 603849 742345 818292 671443 812626 825596 +(Pyro-carbamidomethyl)CHPFYTGQQK MGYG000001315_02623;MGYG000004697_01068;MGYG000002186_01718;MGYG000001645_02131;MGYG000002492_01343;MGYG000000404_01286;MGYG000001718_00208;MGYG000002212_01646;MGYG000001636_00951;MGYG000002145_01593;MGYG000000389_00478;MGYG000000268_00177;MGYG000003694_01383;MGYG000000133_01189;MGYG000002552_02137;MGYG000004681_01708;MGYG000000119_03195;MGYG000002670_00815;MGYG000004414_01891;MGYG000002065_00824;MGYG000000123_03448;MGYG000002278_00861;MGYG000002756_02545;MGYG000001777_00587;MGYG000001310_01807;MGYG000004317_01587;MGYG000000251_00253;MGYG000004884_02111;MGYG000003096_00337;MGYG000000204_00863;MGYG000001338_01040;MGYG000002919_00814;MGYG000000359_01733;MGYG000001193_00607;MGYG000001637_01986;MGYG000000136_00322;MGYG000002312_02603;MGYG000000187_01464;MGYG000002835_02384;MGYG000002970_00284;MGYG000000301_01379;MGYG000000693_00533;MGYG000004548_01514;MGYG000002517_01891;MGYG000000038_00186;MGYG000000356_00302;MGYG000000212_01164;MGYG000004719_00151;MGYG000002985_00203;MGYG000000171_01130;MGYG000004869_02681;MGYG000000493_00772;MGYG000002580_02047;MGYG000003122_00496;MGYG000002978_01849;MGYG000000802_01723;MGYG000001319_00822;MGYG000004296_00580;MGYG000001374_00187;MGYG000000184_01331;MGYG000004558_01746;MGYG000000489_00557;MGYG000000050_03075;MGYG000000484_00653;MGYG000004875_00363;MGYG000000213_02733;MGYG000000201_01344;MGYG000000280_02121;MGYG000000095_02446;MGYG000002961_00396;MGYG000000002_00125;MGYG000000200_00582;MGYG000004785_00522;MGYG000004055_00977;MGYG000000245_01527;MGYG000002947_00032;MGYG000003851_01403;MGYG000000154_00334;MGYG000000206_02001;MGYG000000164_02373;MGYG000002050_00612;MGYG000002775_01690;MGYG000003266_00923;MGYG000002298_01368;MGYG000001607_00699;MGYG000004842_00378;MGYG000004733_03276;MGYG000000188_00340 domain d__Bacteria 1.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZ78@572511|Blautia 0.4318181818181818 186801|Clostridia 0.7727272727272727 J 0.9659090909090909 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family 0.4318181818181818 rpmE 0.5340909090909091 - 1.0 - 0.5681818181818182 ko:K02909 0.5340909090909091 ko03010,map03010 0.5340909090909091 M00178 0.5340909090909091 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.5340909090909091 - 1.0 - 1.0 - 1.0 Ribosomal_L31 0.5340909090909091 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_02623 0.011363636363636364 - - - - 0.5681818181818182 0.5681818181818182 0.5681818181818182 0.5681818181818182 Ribosome 0.5340909090909091 K02909:RP-L31, rpmE; large subunit ribosomal protein L31 0.5340909090909091 none 1.0 6291566 7255669 6956415 6589663 7310162 8971880 6051201 7162217 6041286 6684769 8745329 7636904 8808228 7738943 6663775 8803840 8596285 8404714 6626260 7062751 6881265 8481535 6927474 9486574 6399747 6083349 6802047 7413961 5331145 7609725 7042435 8889190 6645458 7064711 6327187 6602769 6275380 7212293 5280069 9758997 9619619 4726732 7276648 3412622 3791415 5866976 4547193 4611644 6894628 5613843 6625641 3568222 4436365 6349503 11761112 8949455 4466757 4835027 4206750 3608270 13273666 3914193 3807199 4351849 4826939 13757967 5356555 4524519 10625227 7915242 11584102 4784364 5498419 4278084 4120871 7912981 3465134 6469134 8415506 2825756 5716994 4494855 2827026 4033716 4502386 3805470 5855137 5029076 6269229 3578142 3589763 6293466 3448148 9608581 3959414 3841113 3057637 3883997 7728142 3550837 4366289 3473650 4397752 9588071 3622764 4020252 5786267 5775922 6250776 3533085 3207093 3878749 3839287 8648142 6285868 8416253 4568012 5975521 5778733 2844167 3467169 9374050 6869240 4904451 4231920 7825661 5005736 6697779 9090646 4204251 9132799 3064654 5339106 4982628 5474457 2072188 3245592 1908921 9449337 10028822 7900305 2845967 4749105 6385869 7253667 7126109 5042144 8939051 8290851 6778193 10017775 5029825 15860648 14076026 16084192 13642492 14172916 17754504 12958516 14475900 16900334 18325900 15315412 13576068 18725567 15873030 15901587 12335615 15551911 6917454 14978470 13674211 12126730 16590281 8736555 19303498 16543174 17356527 15467019 6400215 14096767 13762351 18816497 22825360 18791628 20555232 14248984 14009609 18635766 18333913 +(Pyro-carbamidomethyl)CHSFYTGQQK MGYG000000172_03808;MGYG000001619_02179;MGYG000002963_00683;MGYG000004359_00097;MGYG000004762_00617;MGYG000001367_03041;MGYG000000233_00887;MGYG000001564_00733;MGYG000000077_01563;MGYG000000087_02394;MGYG000001698_03557;MGYG000002216_00646;MGYG000000398_00199;MGYG000004735_01044;MGYG000002141_00907;MGYG000001688_00648;MGYG000001311_05376;MGYG000000217_00649;MGYG000000205_01476;MGYG000003074_00484;MGYG000004604_01270;MGYG000001797_02586;MGYG000002989_02263;MGYG000002170_01016;MGYG000003001_01693;MGYG000001606_00998;MGYG000000312_01595;MGYG000004781_01785;MGYG000001622_02362;MGYG000000255_02664;MGYG000004380_01297;MGYG000001247_01269;MGYG000003355_01554;MGYG000000135_03652;MGYG000000092_01672;MGYG000001714_00123;MGYG000001954_02190;MGYG000000145_02678;MGYG000001531_01419;MGYG000002445_02309;MGYG000000179_01087;MGYG000001707_01263;MGYG000001199_01801;MGYG000002974_01366 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,220Y9@1506553|Lachnoclostridium 0.5454545454545454 186801|Clostridia 1.0 J 0.8636363636363636 50S ribosomal protein L31 0.5454545454545454 rpmE 0.7727272727272727 - 1.0 - 0.9090909090909091 ko:K02909 0.7727272727272727 ko03010,map03010 0.7727272727272727 M00178 0.7727272727272727 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.7727272727272727 - 1.0 - 1.0 - 1.0 Ribosomal_L31 0.7727272727272727 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000172_03808 0.022727272727272728 - - - - 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Ribosome 0.7727272727272727 K02909:RP-L31, rpmE; large subunit ribosomal protein L31 0.7727272727272727 none 1.0 0 0 0 0 0 2188798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2113411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1975732 0 0 0 0 0 0 0 0 3485409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2713404 0 0 0 0 0 0 0 0 0 0 0 0 2362235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1620300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7563610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2859553 0 0 +(Pyro-carbamidomethyl)CHSQAFTIK MGYG000002494_02089;MGYG000002506_03058 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0136@1|root,COG0136@2|Bacteria,1MUHG@1224|Proteobacteria,1RMN3@1236|Gammaproteobacteria,3ZJ2I@590|Salmonella 0.5 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate 1.0 asd 1.0 GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009090,GO:0009092,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0033554,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.2.1.11 1.0 ko:K00133 1.0 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00017,M00018,M00033,M00525,M00526,M00527 1.0 R02291 1.0 RC00684 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECP_1309.ECP_3527 1.0 Semialdhyde_dh,Semialdhyde_dhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02089 0.5 aspartate-semialdehyde dehydrogenase. L-aspartate-beta-semialdehyde dehydrogenase. - L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Monobactam biosynthesis|Cysteine and methionine metabolism|Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00133:asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11] 1.0 none 1.0 0 0 347897 0 0 0 0 0 0 0 0 0 0 0 0 0 601301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265799 0 0 0 0 224653 0 0 1574445 0 0 0 0 0 0 0 0 0 0 0 0 0 1779536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1352551 0 0 0 0 1262836 0 0 413575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228107 0 0 0 0 328698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CHVLVAMNPSALK MGYG000000196_01836;MGYG000001345_04520 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,2FN08@200643|Bacteroidia,4AM9Z@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 2-oxoacid acceptor oxidoreductase, alpha subunit 1.0 porA 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00174 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFOR_II,POR,POR_N,Transketolase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_01836 0.5 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00174:korA, oorA, oforA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 308608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 839447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CIAEIGTYDPNLEPSAYKVDEEAAKK MGYG000000133_02937 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3Y0EA@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 - 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02937 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1500413 0 0 0 0 0 0 0 0 0 0 3292397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2305867 0 0 0 3408505 0 0 0 0 882581 +(Pyro-carbamidomethyl)CIAGSVADDRK MGYG000003521_00824;MGYG000002438_03055 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,22VUI@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 GGGtGRT protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003521_00824 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 486650 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 768017 0 0 0 0 0 276640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302483 0 0 0 0 0 658279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CIAMGPTDGLVR MGYG000001315_02894;MGYG000000187_00876;MGYG000000028_00163;MGYG000000356_01862;MGYG000002528_01017;MGYG000000262_00505;MGYG000004317_01545;MGYG000001777_00207;MGYG000000562_01724;MGYG000004735_02328;MGYG000002492_00116;MGYG000001543_00548;MGYG000000484_00117;MGYG000002517_03146 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,25UUG@186806|Eubacteriaceae 0.42857142857142855 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 MGYG000001315_02894 0.07142857142857142 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02112:ATPF1B, atpD; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 361001 0 262590 0 0 117139 0 336411 0 358580 0 112399 0 343868 88738 94011 250957 0 486533 0 0 479047 0 0 371494 256394 0 0 0 224802 0 0 106562 321194 355885 256675 139972 0 195270 0 358384 0 0 0 202432 349587 0 0 0 0 0 95036 0 0 0 0 302083 0 0 0 0 260434 145095 200017 286029 0 0 0 0 0 260083 253684 251317 270884 145471 173912 225302 0 377222 0 0 264787 180251 268216 0 0 0 369590 0 250660 220570 0 0 0 296602 0 0 395712 0 0 261178 394681 379363 0 0 142549 0 0 336722 280230 348584 0 115441 267001 860074 0 378987 0 0 397187 476723 850171 0 564253 0 663535 0 1060028 1018461 627473 648200 0 832776 0 0 0 0 0 690973 784784 1082638 0 0 819544 0 0 606927 579675 1006029 777856 967954 333885 619317 0 889449 0 0 477127 619408 588742 0 1000043 0 571089 0 868763 812280 482187 744873 0 634844 0 0 629755 0 431913 733046 638470 762411 0 0 392408 0 0 805649 801596 863539 834865 844033 769120 +(Pyro-carbamidomethyl)CIAMSSTDGLVR MGYG000001300_02368;MGYG000002040_00953;MGYG000004022_00852;MGYG000001065_01646;MGYG000003899_00596;MGYG000002545_01157;MGYG000000036_00372;MGYG000000022_01420;MGYG000001531_01376;MGYG000000195_00674;MGYG000002641_02172;MGYG000002610_02017;MGYG000002274_00866;MGYG000000133_01065;MGYG000002651_01644;MGYG000002780_01575 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3WGVH@541000|Ruminococcaceae 0.75 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 MGYG000001300_02368 0.0625 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02112:ATPF1B, atpD; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 214993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CIDDVSEISAIGHR MGYG000002040_00963 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900758465|m__MGYG000002040 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002040_00963 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407228 0 0 0 0 529257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 688462 0 0 0 0 886284 0 0 0 0 635915 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492229 0 0 0 0 597628 0 0 0 0 719101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 345672 0 0 0 0 0 0 0 0 0 325040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CIDGIVVNAEHC(Carbamidomethyl)K MGYG000001410_00317 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__Sutterella wadsworthensis_A|m__MGYG000001410 1.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2W02M@28216|Betaproteobacteria,4PQCS@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 E 1.0 Fumarase C C-terminus 1.0 aspA 1.0 - 1.0 4.3.1.1 1.0 ko:K01744 1.0 ko00250,ko01100,map00250,map01100 1.0 - 1.0 R00490 1.0 RC00316,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FumaraseC_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001410_00317 1.0 aspartate ammonia-lyase. fumaric aminase. - L-aspartate = fumarate + NH4(+). 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01744:aspA; aspartate ammonia-lyase [EC:4.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 307723 0 0 0 0 0 0 0 413420 0 0 0 0 0 319866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1287325 0 3529144 1369032 0 0 0 0 0 0 1445160 0 0 1895566 0 0 792266 0 1409787 0 0 0 0 0 0 0 0 0 0 2657919 0 0 0 +(Pyro-carbamidomethyl)CIDPIMTYGTEDQKQK MGYG000002517_00542 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00542 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1048699 0 0 1101212 0 0 0 0 0 0 0 0 0 820110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CIDVC(Carbamidomethyl)YHR MGYG000000262_02729;MGYG000000077_00331 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,25W5G@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 glycyl-radical enzyme activating protein family 1.0 pflC 1.0 - 1.0 1.97.1.4 1.0 ko:K04069 1.0 - 1.0 - 1.0 R04710 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4,Fer4_12,Fer4_4,Fer4_6,Fer4_9,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02729 0.5 [formate-C-acetyltransferase]-activating enzyme. pyruvate formate-lyase 1 activating enzyme. A single glycine residue in EC 2.3.1.54 is oxidized to the corresponding radical by transfer of H from its CH2 to AdoMet with concomitant cleavage of the latter.-!-The first stage is reduction of the AdoMet to give methionine and the 5'-deoxyadenosin-5'-yl radical, which then abstracts a hydrogen radical from the glycine residue. glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl- L-methionine = 5'-deoxyadenosine + glycin-2-yl radical-[formate C-acetyltransferase] + H(+) + L-methionine + semiquinone [flavodoxin]. 1.0 1.0 1.0 1.0 - 1.0 K04069:pflA, pflC, pflE; pyruvate formate lyase activating enzyme [EC:1.97.1.4] 1.0 none 1.0 0 532086 127650 0 0 636509 0 130837 0 133990 128363 0 0 0 0 0 0 0 157626 184481 0 532348 0 0 144105 0 0 0 0 0 0 307333 0 0 0 0 0 0 0 229871 0 0 0 0 620545 147130 0 0 0 0 0 0 0 0 0 0 376617 245018 0 0 0 333085 292715 0 253970 0 0 0 136829 0 0 254612 277023 0 0 0 0 1497396 327279 1437950 0 929466 239802 1160133 0 897427 371256 0 0 0 0 0 0 0 1241729 1211667 0 1162368 0 614051 1351981 0 1346564 0 0 0 252905 1004755 533614 1227268 1152034 0 0 144017 0 474898 182689 623140 0 728092 755832 322756 0 855463 308409 0 0 0 0 0 0 0 237023 644749 0 525342 0 586584 305757 0 454717 0 0 0 322447 222731 431346 0 378609 0 0 311179 0 1122073 942967 559054 0 629961 415882 585719 0 821823 931256 0 0 0 0 0 0 0 754194 671063 0 804888 0 513306 428276 0 449403 0 0 0 1560148 1254793 1538325 928729 534276 0 0 1336470 +(Pyro-carbamidomethyl)CIDYVAAHPEVR MGYG000002882_00084;MGYG000002720_00860;MGYG000002926_00665;MGYG000004525_00411;MGYG000002143_01958;MGYG000001733_00673;MGYG000004196_01674;MGYG000004487_00298 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,25UUF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 E 1.0 Lysine-2,3-aminomutase 1.0 kamA 1.0 - 1.0 5.4.3.2 1.0 ko:K01843 1.0 ko00310,map00310 1.0 - 1.0 R00461 1.0 RC00303 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,LAM_C,Radical_SAM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002882_00084 0.125 lysine 2,3-aminomutase. - This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-It contains pyridoxal phosphate and a [4Fe-4S] cluster and binds an exchangeable S-adenosyl-L-methionine molecule.-!-Activity in vitro requires a strong reductant such as dithionite and strictly anaerobic conditions.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of S-adenosyl-L-methionine, mediated by the iron- sulfur cluster.-!-S-adenosyl-L-methionine is regenerated at the end of the reaction. L-lysine = (3S)-3,6-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K01843:kamA; lysine 2,3-aminomutase [EC:5.4.3.2] 1.0 none 1.0 3607834 2865598 2071000 3788568 0 3313926 0 5178157 4742478 3232045 2535399 2485609 0 3333088 3900624 2294969 3283397 0 3366565 3234248 0 2671342 0 2889600 3767761 4281999 3509217 0 3767762 2106893 0 0 2209663 4024915 3739803 4484891 3679876 2097934 1192347 281644 229869 1310702 0 217137 0 1209216 1071443 915801 0 358141 0 865225 795730 0 432436 0 1276935 1052762 0 0 0 431419 744822 878347 1247781 0 1092777 750177 0 0 152646 840073 1270976 1025452 1227329 469439 3146539 2333568 2664247 3556558 0 1715456 0 3212412 2976495 3037299 1603492 2625240 0 3405234 3445752 1667155 3149762 0 5237803 2962429 0 2265369 0 1466117 3236273 3770503 3189672 0 2946099 2724077 0 0 2252902 4241383 3612849 3029050 3447450 2867561 1772101 1692903 1687357 1755619 0 1864266 0 1913896 1846935 1848644 964671 1054742 0 1705076 1640643 1481307 2155779 0 2439007 1622872 0 1254596 0 1089198 1303541 1933768 2017796 0 2724733 1710537 0 0 1349084 1663533 1823802 1786348 1444496 1582840 0 392912 0 317965 0 466650 0 0 0 0 310777 0 0 0 0 0 472983 0 719063 681671 0 0 0 0 209230 392351 657436 0 0 0 0 0 0 0 0 0 452619 0 +(Pyro-carbamidomethyl)CIEEIGTYDPTKDPSEYHVNEELAKK MGYG000002492_01364;MGYG000000154_00276;MGYG000002517_01931;MGYG000004719_01372;MGYG000000271_00791;MGYG000004271_01605;MGYG000000489_02523;MGYG000002670_00836 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 - 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01364 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 786915 0 0 1105406 0 0 0 901585 898080 0 0 0 0 0 0 0 0 0 894282 0 0 0 0 0 0 960374 0 0 0 0 0 0 0 0 573176 662963 421625 0 234943 0 0 443038 0 0 0 445965 0 0 0 0 0 0 0 0 0 0 315241 0 0 0 0 0 0 312903 0 0 0 0 0 0 0 0 0 241114 0 0 727801 0 0 469303 0 0 0 314400 496053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2127277 0 0 0 0 0 0 0 0 0 0 428992 0 1376507 0 0 1791040 0 0 0 1989547 1441416 0 0 0 0 0 0 0 0 0 1401562 0 0 0 0 0 0 1634572 0 0 0 0 0 0 0 0 1775856 1471409 1709538 0 1287576 0 0 284667 0 0 0 772276 1787884 0 0 0 0 0 0 0 0 0 1417013 0 0 0 0 0 0 1837600 0 0 0 0 0 0 0 0 1247247 1968892 2245342 0 +(Pyro-carbamidomethyl)CIEGVYHTGQR MGYG000000142_02504;MGYG000001338_02427;MGYG000004733_01559;MGYG000002298_01762;MGYG000000201_00496;MGYG000000216_02766;MGYG000004296_01205;MGYG000000133_01784 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3XZDK@572511|Blautia 0.75 186801|Clostridia 1.0 C 1.0 acetyl-CoA decarbonylase synthase complex subunit beta 0.75 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_02504 0.125 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 0 609446 858171 0 1308138 0 0 0 0 0 0 0 0 0 0 0 0 1086878 0 0 0 0 457578 0 0 0 0 659106 0 0 0 0 492511 0 0 0 0 629154 0 215049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154269 0 0 336385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427176 0 0 0 0 359186 0 2287602 964974 0 1761144 0 0 0 0 0 0 0 0 0 0 0 0 519071 0 0 0 0 0 0 0 0 0 1245567 0 0 2109708 0 1530154 0 0 0 0 1421719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CIGGGM(Oxidation)GC(Carbamidomethyl)STIVERD MGYG000000262_02231;MGYG000000404_01795;MGYG000000204_00804;MGYG000000997_00552;MGYG000000077_02464;MGYG000000164_00683;MGYG000001814_02499;MGYG000002517_00540;MGYG000000153_01463;MGYG000000389_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.4 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.7 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02231 0.1 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CIGGGMGC(Carbamidomethyl)ATIVERD MGYG000000205_02136;MGYG000002445_02272;MGYG000000233_02446;MGYG000001617_02042;MGYG000000255_01552;MGYG000001711_01126;MGYG000001615_04304;MGYG000000281_02192;MGYG000001315_01871 domain d__Bacteria 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,4BWBU@830|Butyrivibrio 0.3333333333333333 186801|Clostridia 0.8888888888888888 I 1.0 Thiolase, C-terminal domain 0.6666666666666666 thlA 0.8888888888888888 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02136 0.1111111111111111 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291111 0 0 0 0 567699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CIGGGMGC(Carbamidomethyl)STIVER MGYG000000262_02231;MGYG000000404_01795;MGYG000000204_00804;MGYG000000997_00552;MGYG000004271_00231;MGYG000000164_00683;MGYG000001814_02499;MGYG000000245_02019;MGYG000000271_02104;MGYG000002517_00540;MGYG000000389_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.5454545454545454 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.7272727272727273 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02231 0.09090909090909091 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 429295 0 0 829962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368638 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CIGGGMGC(Carbamidomethyl)STIVERD MGYG000000262_02231;MGYG000000404_01795;MGYG000000204_00804;MGYG000000997_00552;MGYG000000077_02464;MGYG000000164_00683;MGYG000001814_02499;MGYG000002517_00540;MGYG000000153_01463;MGYG000000389_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.4 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.7 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02231 0.1 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 333058 0 0 551724 0 695709 283474 0 0 0 591845 0 0 0 581385 257432 402940 0 0 0 532524 541324 419953 0 0 0 0 0 0 461760 335881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2054856 1081911 832725 3331477 1931165 1535489 2004192 2920302 3957978 2156770 1251804 1632459 1392277 3555511 3433288 1447096 2854234 0 3059234 3381422 2212499 811044 0 738000 2010294 2107536 2497160 0 1168700 3259586 1218584 1325487 957633 1600516 3694096 2126224 3094152 1046809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CIHSC(Carbamidomethyl)PFGAIGSK MGYG000004271_01048;MGYG000000271_00447;MGYG000000179_00443;MGYG000001065_01137;MGYG000002234_01825;MGYG000000389_00676;MGYG000002517_01844;MGYG000002670_00991;MGYG000002492_02180 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1143@1|root,COG4624@1|root,COG1143@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Iron only hydrogenase large subunit, C-terminal domain 0.6666666666666666 - 1.0 - 1.0 1.12.7.2 1.0 ko:K00533 1.0 - 1.0 - 1.0 R00019 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe_hyd_lg_C,Fer4,Fer4_6,Fer4_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01048 0.1111111111111111 ferredoxin hydrogenase. uptake hydrogenase. Can use molecular hydrogen for the reduction of a variety of substances.-!-Formerly EC 1.12.1.1, EC 1.12.7.1, EC 1.18.3.1, EC 1.18.99.1 and EC 1.98.1.1. H2 + 2 oxidized [2Fe-2S]-[ferredoxin] = 2 H(+) + 2 reduced [2Fe-2S]- [ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K00533:E1.12.7.2L; ferredoxin hydrogenase large subunit [EC:1.12.7.2] 1.0 none 1.0 0 0 0 737943 0 0 0 0 0 0 0 345581 0 395920 777809 0 0 0 0 0 0 0 0 0 0 0 571176 0 0 0 0 0 0 525285 0 557182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1731788 0 0 0 0 0 0 0 785126 0 2270331 2218375 0 0 0 0 0 0 0 0 0 0 0 1939015 0 0 0 0 0 0 1266874 0 1325329 0 0 0 0 0 0 0 0 0 0 0 0 0 1326573 0 1733336 0 0 0 0 0 0 0 0 0 0 0 0 1088099 0 0 0 0 0 0 1614702 0 1683835 0 0 +(Pyro-carbamidomethyl)CIHVHATDFDR MGYG000002560_03190;MGYG000000243_01312;MGYG000002478_03183 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0438@1|root,COG0438@2|Bacteria,4NEWR@976|Bacteroidetes,2FMW0@200643|Bacteroidia,4AKN5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Glycosyltransferase, group 1 family protein 1.0 gmhA 1.0 - 1.0 2.4.1.346 1.0 ko:K13668 1.0 - 1.0 - 1.0 R11703,R11704 1.0 - 1.0 ko00000,ko01000,ko01003 1.0 - 1.0 GT4 1.0 - 1.0 Glyco_trans_4_4,Glyco_transf_4,Glyco_transf_5,Glycos_transf_1,SIS_2 1.0 - 1.0 GT4 1.0 GT4 1.0 GT4 1.0 MGYG000002560_03190 0.3333333333333333 phosphatidyl-myo-inositol dimannoside synthase. mannosyltransferase. The enzyme, found in Corynebacteriales, is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs). (1) a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-mannopyranosyl-(1<->6)-D- myo-inositol] + GDP-alpha-D-mannose = a 2,6-O-bis(alpha-D- mannopyranosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+). (2) a 1,2-diacyl-sn-glycero-3-phospho-[alpha-D-6-acyl-mannopyranosyl- (1<->6)-D-myo-inositol] + GDP-alpha-D-mannose = 2-O-(alpha-D-mannosyl)-6- O-(6-O-acyl-alpha-D-mannosyl)-1-phosphatidyl-1D-myo-inositol + GDP + H(+). 1.0 1.0 1.0 1.0 - 1.0 K13668:pimB; phosphatidyl-myo-inositol dimannoside synthase [EC:2.4.1.346] 1.0 none 1.0 0 0 0 0 255866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CILFNEK MGYG000001315_01111;MGYG000004733_00600;MGYG000001687_00314;MGYG000001564_01809;MGYG000000038_01493;MGYG000000077_01442;MGYG000002670_00126;MGYG000000268_00688;MGYG000001619_01501;MGYG000001476_03312;MGYG000004630_02409;MGYG000000164_01754;MGYG000002274_01022;MGYG000000404_00178;MGYG000000271_02110;MGYG000001338_01881;MGYG000002517_00259;MGYG000001493_05223;MGYG000004785_01998;MGYG000000262_02304;MGYG000000205_00108;MGYG000000252_02425;MGYG000002934_02584;MGYG000003142_01159;MGYG000000489_01562;MGYG000000301_00099;MGYG000002312_03080;MGYG000000213_01204;MGYG000000245_01078;MGYG000000145_02287;MGYG000000389_02030;MGYG000003801_01473;MGYG000000184_02616;MGYG000004558_00607;MGYG000004087_02483;MGYG000001617_02316;MGYG000001439_02537;MGYG000002279_02521;MGYG000000179_02171;MGYG000002105_01106;MGYG000001007_01036;MGYG000000087_01966;MGYG000000198_04024;MGYG000000095_02480 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 0.2727272727272727 186801|Clostridia 0.9545454545454546 F 0.5681818181818182 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 0.9772727272727273 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01111 0.022727272727272728 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 157627 0 0 0 0 0 66669 175060 353991 82793 0 0 0 0 235608 37980 0 0 109096 0 450623 0 0 0 0 123671 67814 0 0 0 0 0 0 0 59310 79866 137487 0 0 0 0 0 0 0 82568 0 90139 0 0 0 0 0 266820 0 0 0 341580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86053 58138 46094 0 296340 0 0 228005 0 0 136673 177430 77928 142783 0 0 0 0 350233 0 104077 0 241485 0 144352 0 0 0 0 274319 221046 0 0 183161 0 0 0 0 0 150293 267704 0 800662 0 0 627258 0 0 483534 636357 760362 382135 0 0 0 0 621300 361479 523568 0 806830 0 481379 0 0 0 0 405289 695132 0 0 484132 0 0 0 0 526171 594019 800627 0 554273 0 0 82898 0 0 735777 439090 491463 351041 0 0 0 0 530533 246485 560292 0 430108 0 531479 0 0 0 0 198998 191664 0 0 232349 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CILFNEKGDMC(Carbamidomethyl)SVAQK MGYG000000198_04024 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04024 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 1830949 0 0 1364250 0 0 0 0 0 0 0 0 0 0 1186831 0 0 0 0 2048493 1206411 0 0 0 0 1382944 1432811 0 1503764 0 0 0 0 0 0 0 1574741 0 498501 0 0 782045 0 0 0 0 0 0 0 0 0 0 447859 0 0 0 0 417200 468012 0 0 0 0 698373 865682 0 808534 0 0 0 0 0 0 0 577352 0 1778073 0 0 2040359 0 0 0 0 0 0 0 0 0 0 1848659 0 0 0 0 1470557 1485538 0 0 0 0 1649110 2010833 0 2170756 0 0 0 0 0 0 0 1520332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682761 0 0 0 0 0 0 0 0 0 0 0 0 0 702361 0 0 0 0 506589 542122 0 0 0 0 803204 910659 0 770587 0 0 0 0 0 0 0 598803 0 +(Pyro-carbamidomethyl)CILFNEKGEMC(Carbamidomethyl)SVAQK MGYG000002934_02584;MGYG000001564_01809;MGYG000000489_01562;MGYG000002670_00126;MGYG000000268_00688;MGYG000000067_02180;MGYG000000145_02287;MGYG000001619_01501;MGYG000001476_03312;MGYG000000389_02030;MGYG000000164_01754;MGYG000002274_01022;MGYG000000404_00178;MGYG000004087_02483;MGYG000002517_00259;MGYG000001493_05223;MGYG000000179_02171;MGYG000002105_01106;MGYG000001007_01036 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 0.3684210526315789 186801|Clostridia 0.8947368421052632 C 0.47368421052631576 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002934_02584 0.05263157894736842 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 5273230 3281247 2066516 2978962 2998017 2758501 5387328 5436209 6504822 7115368 2141488 2074124 0 4646114 4340648 3221037 3744022 0 4222038 5648669 4873767 2139205 0 1166766 6558235 4158128 4265644 0 4623022 3904846 633825 0 1189263 3728655 6104154 4358862 4594597 1056723 0 351634 323769 345063 663723 201573 360246 0 418063 270058 0 0 0 562030 0 0 0 0 205505 374288 0 0 0 389681 189196 366323 413644 0 726317 492815 494398 0 400234 361901 349393 289795 124883 412005 1693139 585805 487522 1365926 269576 0 926508 1117251 1254482 2195319 294691 852270 0 1534668 1956895 821510 982089 0 1287691 1503298 1317563 660724 0 0 1061159 1209661 1896815 0 1546733 648508 0 0 833011 694183 1994449 1442908 1614998 292769 3423803 443588 866151 2353011 1132357 996961 2085502 4012957 5132669 1335001 600349 1700501 0 3635619 3467937 1151963 2053306 0 3285947 3191085 3103953 0 0 539966 4273128 5630509 4342964 0 682426 1934701 0 0 736668 3382770 4746590 3585782 5199829 539985 8369847 4213700 6235922 3566302 4270650 5180681 7946458 4512515 11047390 9325049 5483721 6898095 0 14964057 9788085 3923727 8038765 0 7644633 7554649 7562295 5966057 0 5290343 11633411 10997243 10609841 0 6899040 4861290 5915716 0 9135109 9244305 9031902 13025245 12730112 9339195 +(Pyro-carbamidomethyl)CILFNEKGEMC(Carbamidomethyl)SVAQR MGYG000001315_01111;MGYG000004733_00600;MGYG000004558_00607;MGYG000000038_01493;MGYG000002279_02521;MGYG000000245_01078;MGYG000000205_00108;MGYG000000252_02425 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,27V84@189330|Dorea 0.875 186801|Clostridia 1.0 F 0.875 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01111 0.125 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 1543149 1135544 1471654 1009220 1342312 972441 991762 2190339 1224092 1745723 1342899 1345290 0 1458164 1299427 1246516 1378670 0 1499007 1611345 1133748 888779 0 389079 1537223 1082871 1008743 0 0 0 544147 0 740408 1429261 1513121 1147414 981937 394846 1509952 1317858 633195 2092694 915987 678344 1193952 1280094 1230568 1161277 766126 724335 0 889946 1192178 335985 710009 0 1032239 1466722 1028288 451433 0 1135738 1288543 1407844 1331387 0 0 0 1422331 0 809404 1843762 1332546 1250932 1187639 683048 1681410 278206 589070 1587621 0 255505 971163 1375531 1178942 918878 666400 899024 0 1192488 1419814 1166734 1104696 0 1925067 1798476 819453 1129451 0 207812 1619487 1153250 1694713 0 0 0 374518 0 1015341 1912045 1143875 1197712 1326968 626827 480673 338303 0 513278 0 0 667471 788051 505290 523771 0 391560 0 129181 684781 0 595069 0 508825 0 675826 0 0 0 910695 570931 596044 0 0 0 382179 0 240063 449792 535512 616103 361427 0 0 393177 190834 637185 0 397511 175676 290351 279252 0 592030 109794 0 0 389940 129448 106421 0 268558 95038 202837 454818 0 377839 335383 95058 258285 0 0 0 542860 0 0 681408 0 304424 76870 511574 +(Pyro-carbamidomethyl)CILNGLGK MGYG000000013_02686;MGYG000003420_01320;MGYG000000273_02192;MGYG000003221_02162;MGYG000003470_00018;MGYG000003922_03053;MGYG000003693_01584;MGYG000002455_00321;MGYG000004824_01069;MGYG000000781_01514;MGYG000001604_01691;MGYG000004464_00921;MGYG000000042_01753;MGYG000000029_00187;MGYG000000196_00899;MGYG000001378_03489;MGYG000004763_01967;MGYG000002281_03938;MGYG000001599_00424;MGYG000004797_02907;MGYG000001925_01569;MGYG000001346_01121;MGYG000002478_02896;MGYG000004019_01333;MGYG000000043_00846 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.88 976|Bacteroidetes 1.0 S 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_02686 0.04 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 342214 0 0 0 0 0 0 0 0 0 201129 243561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 430202 0 0 0 0 0 0 0 0 0 327263 495987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464169 0 0 0 0 0 0 0 0 0 289253 339249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675370 0 0 0 0 0 0 0 0 0 338130 628115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CINDVSEIDAIGHR MGYG000001300_02904;MGYG000001627_01221;MGYG000002619_01707;MGYG000003899_00603 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02904 0.25 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1527174 0 0 0 0 899836 0 377100 0 0 1155711 0 0 0 0 0 440500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519078 0 0 0 0 768141 0 699555 0 0 794432 0 0 368614 0 0 421362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724737 0 0 0 0 514851 0 339252 0 0 852830 0 0 540381 0 0 300591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1324234 0 0 0 0 1528390 0 672802 0 0 1997059 0 0 740171 0 0 551707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CIPGSVADDRK MGYG000000013_02686;MGYG000003420_01320;MGYG000004047_01253;MGYG000000347_00819;MGYG000002455_00321;MGYG000000269_00015;MGYG000000781_01514;MGYG000001400_01185;MGYG000004561_02010;MGYG000000196_00899;MGYG000004763_01967;MGYG000004797_02907;MGYG000001423_03082;MGYG000001925_01569;MGYG000001806_00888;MGYG000001346_01121;MGYG000000215_01600;MGYG000003535_01608;MGYG000001871_01775;MGYG000002293_01605;MGYG000000273_02192;MGYG000003470_00018;MGYG000003221_02162;MGYG000003922_03053;MGYG000003693_01584;MGYG000002603_00277;MGYG000001415_02505;MGYG000002080_00203;MGYG000002275_01873;MGYG000001770_01218;MGYG000001604_01691;MGYG000002834_01893;MGYG000002108_00627;MGYG000001697_00682;MGYG000004464_00921;MGYG000000029_00187;MGYG000001378_03489;MGYG000004185_01308;MGYG000000045_01847;MGYG000002281_03938;MGYG000001599_00424;MGYG000000374_01026;MGYG000000707_02290;MGYG000000345_00815;MGYG000000433_01203;MGYG000000989_03267;MGYG000003446_01092;MGYG000004019_01333;MGYG000002478_02896;MGYG000000223_01510;MGYG000001785_00655 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.45098039215686275 976|Bacteroidetes 0.7450980392156863 S 1.0 Psort location Cytoplasmic, score 8.96 0.7254901960784313 - 0.9019607843137255 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_02686 0.0196078431372549 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1693626 1310661 0 1387382 2745205 1617138 0 1273358 1470129 1395036 0 1640830 2495253 2049172 1821789 2451307 1655652 1604120 1574313 1685547 1705500 1260788 1748889 1672883 1464795 1763876 1780237 1453648 1435242 1649153 1814776 1886966 2329157 1552157 1751463 1820578 1480826 2307009 1303602 887683 1643022 1600138 1182468 1204309 1114048 1414434 1534304 1299369 1456281 1468887 1694221 1220173 1164444 1832982 1154325 1110848 1314072 1288139 1239125 1047320 1594234 838031 1385490 1426471 1024338 1574775 1186753 1590973 737674 1046457 1282990 1126605 1750559 1060799 1431544 1050733 1134654 419239 1390602 816279 1533030 953971 1183578 860875 1308059 945915 1387276 405397 1491489 970790 920427 1012138 944774 1676666 950617 818184 1101546 566832 1216245 882984 1025317 629203 895827 1392563 1140722 1217578 1048241 695406 952665 553087 1051294 1347227 968469 998524 1989421 2989097 4924032 2204143 3679200 4601065 2783315 2424920 2345841 2981102 5479072 2846559 3386450 1991051 2268987 4199869 2508955 6584922 2740328 1853776 1860003 5322952 5401127 4813023 2955592 2671331 2383162 8157336 3263573 2026431 3459029 3890942 4390784 2290129 2806758 2604827 2597456 4883306 788136 421176 175630 364368 1150952 0 835479 1165974 789186 360539 360300 653061 808869 388340 611996 1144138 506427 2860099 850682 1112956 593950 215158 2188391 287592 774875 760008 0 2043272 456386 1264679 404131 471273 193719 1109197 404475 430300 852311 237862 +(Pyro-carbamidomethyl)CIPGSVADHR MGYG000003425_04615;MGYG000002517_01686;MGYG000002492_01963 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 0.6666666666666666 183925|Methanobacteria 0.6666666666666666 F 0.6666666666666666 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 0.6666666666666666 purD 0.6666666666666666 - 1.0 6.3.4.13 0.6666666666666666 ko:K01945 0.6666666666666666 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 0.6666666666666666 M00048 0.6666666666666666 R04144 0.6666666666666666 RC00090,RC00166 0.6666666666666666 ko00000,ko00001,ko00002,ko01000 0.6666666666666666 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003425_04615 0.3333333333333333 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 0.6666666666666666 K01945:purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] 0.6666666666666666 none 1.0 0 0 256622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610696 0 0 0 0 492940 0 0 301603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596557 0 0 0 0 530060 0 0 1088563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 868916 0 0 0 0 1210098 0 0 812182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332905 0 0 0 0 670408 0 0 497086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CIPVHGTNQSK MGYG000002293_02708;MGYG000003697_02283;MGYG000000272_01790 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_02708 0.3333333333333333 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 184968 0 0 0 0 0 0 220414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287930 0 0 0 0 167280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4377582 0 0 0 0 0 0 1781584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4008618 0 0 0 0 4180823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250759 +(Pyro-carbamidomethyl)CISC(Carbamidomethyl)GIC(Carbamidomethyl)ATK MGYG000002485_02284 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG1142@1|root,COG2878@1|root,COG1142@2|Bacteria,COG2878@2|Bacteria,378T9@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Putative Fe-S cluster 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_02284 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03616:rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 841578 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKDAGVVMTGAGATYPYGKDPHDSNIR MGYG000000255_01546;MGYG000000205_02142 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,21Z64@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 EK 1.0 COG COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Aminotran_MocR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01546 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 1763106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1752094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 906522 0 0 0 0 0 0 0 0 0 0 0 748258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 977949 0 0 0 0 0 0 0 0 0 0 0 486401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 765160 0 0 0 0 +(Pyro-carbamidomethyl)CKDFVGR MGYG000000254_00985 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Marinifilaceae|g__Odoribacter|s__Odoribacter splanchnicus|m__MGYG000000254 1.0 COG3746@1|root,COG3746@2|Bacteria,4NIID@976|Bacteroidetes,2FN19@200643|Bacteroidia,22Z0H@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Phosphate-selective porin O and P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Porin_4,Porin_O_P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000254_00985 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1120006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 694192 0 0 0 0 +(Pyro-carbamidomethyl)CKEALGYIAEAR MGYG000002478_03489 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0800@1|root,COG0800@2|Bacteria,4NEFY@976|Bacteroidetes,2FNWD@200643|Bacteroidia,4AMHW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 KDPG and KHG aldolase 1.0 eda 1.0 - 1.0 4.1.2.14,4.1.3.42 1.0 ko:K01625 1.0 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 1.0 M00008,M00061,M00308,M00631 1.0 R00470,R05605 1.0 RC00307,RC00308,RC00435 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_03489 1.0 2-dehydro-3-deoxy-phosphogluconate aldolase. | (4S)-4-hydroxy-2-oxoglutarate aldolase. phospho-2-keto-3-deoxygluconate aldolase. | hydroxyketoglutaric aldolase. The enzyme shows no activity with 2-dehydro-3-deoxy-6-phosphate-D- galactonate (cf. EC 4.1.2.55).-!-Also acts on 2-oxobutanoate. | The enzyme from the bacterium Escherichia coli is specific for the (S) enantiomer.-!-That enzyme is trifunctional, and also catalyzes the reactions of EC 4.1.1.3 and EC 4.1.2.14. cf. EC 4.1.3.16. 2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate. | (4S)-4-hydroxy-2-oxoglutarate = glyoxylate + pyruvate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Glyoxylate and dicarboxylate metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01625:eda; 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKEALQDR MGYG000001300_02377;MGYG000002040_00944;MGYG000002641_02163;MGYG000003899_00586 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3WGRA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Synthesizes alpha-1,4-glucan chains using ADP-glucose 1.0 glgA 1.0 - 1.0 2.4.1.21 1.0 ko:K00703 1.0 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 1.0 M00565 1.0 R02421 1.0 RC00005 1.0 ko00000,ko00001,ko00002,ko01000,ko01003 1.0 - 1.0 GT5 1.0 - 1.0 Glyco_transf_5,Glycos_transf_1,HC2 1.0 2.4.1.21 0.75 GT5 1.0 GT5 0.75 GT5 1.0 MGYG000001300_02377 0.25 starch synthase. starch (bacterial glycogen) synthase. The description (accepted name) varies according to the source of the enzyme and the nature of its synthetic product, e.g. starch synthase, bacterial glycogen synthase.-!-A similar enzyme utilizes UDP-alpha-D-glucose (cf. EC 2.4.1.11). [(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-alpha-D- glucosyl](n+1) + ADP + H(+). 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biofilm formation - Escherichia coli 1.0 K00703:glgA; starch synthase [EC:2.4.1.21] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641796 576718 1178831 0 0 0 0 1144897 0 0 0 0 1129001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797621 0 897226 0 0 442276 0 0 762885 351640 809041 518976 966035 0 0 0 833682 0 0 0 0 1039817 0 0 0 0 0 679921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 500580 0 0 0 0 505415 0 0 0 0 545205 0 0 0 0 0 269716 0 0 0 0 0 0 0 0 0 0 1244405 0 1082228 0 0 1160495 0 0 899576 1053988 1193405 1061498 1417115 0 0 0 803943 0 0 0 0 1103502 0 0 0 0 0 1278595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232214 0 0 0 0 137163 0 0 0 0 301871 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKEDIAETAR MGYG000000205_03218;MGYG000000233_00909 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 29UEJ@1|root,30FRA@2|Bacteria,1UEGZ@1239|Firmicutes,25JDX@186801|Clostridia,2228T@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_03218 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 259517 0 0 223653 0 0 0 521429 0 412519 0 0 0 414769 0 0 296462 0 0 591768 0 0 0 0 0 227749 0 0 0 0 0 0 0 473828 0 0 366757 0 1181543 0 0 1453991 0 0 0 1121400 0 1278853 0 0 0 1258815 0 0 933759 0 1023446 920717 0 0 0 0 0 948554 0 0 0 0 0 0 0 1515456 0 0 1006661 0 0 0 0 0 0 0 0 565393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401654 0 0 0 0 0 0 0 0 0 0 460168 0 297764 0 0 131217 0 0 0 0 0 718656 0 0 0 0 0 0 274525 0 480575 0 0 0 0 0 0 550317 0 0 0 0 0 0 0 498587 0 0 0 0 0 0 0 253031 0 0 0 374333 0 320899 0 0 0 263173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282090 0 0 0 0 +(Pyro-carbamidomethyl)CKEFTTPEGR MGYG000000236_01485;MGYG000004797_01485;MGYG000000243_02209;MGYG000002171_02378;MGYG000002560_02265;MGYG000002478_02033;MGYG000001346_00878 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,2FMPI@200643|Bacteroidia,4AP54@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_01485 0.14285714285714285 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1960820 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858576 906173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 738350 659097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427573 868935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKEFVTAEGQQK MGYG000002492_00955 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00955 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 0 0 238730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563658 0 0 2054323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2379470 0 0 0 0 2016614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKEQGVNVR MGYG000000090_02531;MGYG000002116_00410 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes 0.5 1239|Firmicutes 0.5 H 1.0 Belongs to the formate--tetrahydrofolate ligase family 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000090_02531 0.5 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01938:fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 880210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 566734 0 0 0 0 666224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124973 +(Pyro-carbamidomethyl)CKEVELGTMNLDHIR MGYG000000142_01106 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WHXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 FAD binding domain 1.0 - 1.0 - 1.0 1.3.5.1,1.3.5.4,1.3.99.33 1.0 ko:K00239,ko:K00244,ko:K17363 1.0 ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 1.0 M00009,M00011,M00149,M00150,M00173,M00374,M00376 1.0 R02164,R10330 1.0 RC00045,RC00669 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,FMN_bind,FMN_red 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01106 1.0 succinate dehydrogenase. | urocanate reductase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. | The enzyme functions as part of an anaerobic electron transfer chain that utilizes urocanate as the terminal electron acceptor.-!-The activity has been demonstrated with the artificial donor reduced methyl viologen. a quinone + succinate = a quinol + fumarate. | A + dihydrourocanate = AH2 + urocanate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Histidine metabolism|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Two-component system|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]|K00244:frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]|K17363:urdA; urocanate reductase [EC:1.3.99.33] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 745072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKIEQAPGQHGAR MGYG000000235_04517;MGYG000002515_03179;MGYG000002323_00410;MGYG000002494_02445;MGYG000002507_04205;MGYG000002477_00163;MGYG000002506_02937;MGYG000002534_00416;MGYG000002535_00001;MGYG000002366_00460;MGYG000000093_01116 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,3XNVS@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000235_04517 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 1078475 794758 970944 160621 904456 1380366 1014778 1306490 847287 1395303 0 800641 540162 1171484 877240 559827 770537 0 122416 1297750 0 1783662 0 1767553 1011259 906794 0 0 1125956 1091648 585375 0 931881 1187471 1114184 784575 916052 768164 0 3064737 3336483 2994317 3081939 5983419 3146674 2507108 2951309 5128383 0 2549664 1779392 3434993 2909348 2310992 3170847 0 3749628 2395998 0 6145172 0 4374790 4052018 2764357 0 0 3785987 3759115 1569489 0 3630790 2894686 2937550 2506872 2126808 2958249 1316813 1209527 1402333 327101 1048680 1793619 1196712 1269409 1130283 1671822 0 833349 1128994 990617 993790 1066647 834300 0 1049529 1262131 0 1678327 0 1623330 848427 1324839 0 0 1023032 1139911 910430 0 1074805 1466580 1214552 1097600 1074757 1007432 1937966 1446501 1642762 1676386 1200924 2125971 1949159 2492349 1812852 2143794 0 1584868 1722808 1968213 1764768 1491299 284881 0 1898044 1440599 0 2324496 0 1415228 2498202 1971028 0 0 1653749 1863621 884654 0 1732143 2936026 2745911 2138615 1228820 996243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41741 0 0 0 0 0 233100 0 0 0 +(Pyro-carbamidomethyl)CKIEQVC(Carbamidomethyl)PMK MGYG000004735_02134 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG2221@1|root,COG2221@2|Bacteria,1UI1A@1239|Firmicutes,25EAA@186801|Clostridia,27UCZ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Nitrite/Sulfite reductase ferredoxin-like half domain 1.0 dsvA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 C_GCAxxG_C_C,Fer4,Fer4_10,NIR_SIR,NIR_SIR_ferr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_02134 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2048585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKLEQAPGQHGAR MGYG000002515_03179;MGYG000002494_02445;MGYG000001465_00016;MGYG000002477_00163;MGYG000002534_00416 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,3XNVS@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_03179 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3219106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2281931 0 0 0 0 0 0 0 0 0 0 0 602644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKNDEETIR MGYG000002549_01439 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,2FN44@200643|Bacteroidia,4AKAD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway 1.0 nqrF 1.0 - 1.0 1.6.5.8 1.0 ko:K00351 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_6,Fer2,NAD_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_01439 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 - 1.0 K00351:nqrF; Na+-transporting NADH:ubiquinone oxidoreductase subunit F [EC:7.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 798537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1159985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 681907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKNEEETIR MGYG000001306_00763 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,2FN44@200643|Bacteroidia,4AKAD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway 1.0 nqrF 1.0 - 1.0 1.6.5.8 1.0 ko:K00351 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_6,Fer2,NAD_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_00763 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 - 1.0 K00351:nqrF; Na+-transporting NADH:ubiquinone oxidoreductase subunit F [EC:7.2.1.1] 1.0 none 1.0 0 0 577426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545011 0 0 0 0 602435 0 0 0 0 302044 0 0 0 0 432333 0 0 0 0 731757 0 0 895813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1902944 0 0 0 0 8517890 0 0 0 0 9061562 0 0 0 0 244420 0 0 0 0 342106 0 0 314366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244130 0 0 0 0 0 0 0 0 0 326015 0 0 449752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139801 0 0 0 0 0 0 0 0 0 202822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055390 0 0 0 0 494469 0 0 0 0 310648 0 0 0 0 171349 0 0 0 0 327768 +(Pyro-carbamidomethyl)CKNTEETIR MGYG000002478_03723;MGYG000000243_00371 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,2FN44@200643|Bacteroidia,4AKAD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway 1.0 nqrF 1.0 - 1.0 1.6.5.8 1.0 ko:K00351 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_6,Fer2,NAD_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_03723 0.5 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 - 1.0 K00351:nqrF; Na+-transporting NADH:ubiquinone oxidoreductase subunit F [EC:7.2.1.1] 1.0 none 1.0 1030557 1000701 2379723 848954 1945112 0 0 0 897517 0 0 0 2090320 1031371 0 2021518 0 1058982 0 0 0 0 1245270 0 0 903713 0 735391 0 0 0 0 2032410 0 1043620 0 1246846 1972547 511268 284568 413842 442069 939813 0 0 0 415019 0 0 0 1326361 373385 0 913887 0 105762 0 0 0 0 369767 0 0 603318 0 165446 0 0 0 0 422433 0 532615 0 378284 418896 358162 380350 692712 448917 756307 0 0 0 428210 0 0 0 1014084 437037 0 722031 0 509797 0 0 0 0 152476 0 0 433333 0 767791 0 0 0 0 344833 0 758831 0 522494 670152 0 0 0 0 0 0 0 0 0 0 0 0 0 991490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 652682 0 0 0 0 0 352858 341801 290761 483349 613845 0 0 0 432721 0 0 0 1887630 77603 0 1020996 0 852157 0 0 0 0 570032 0 0 764706 0 452606 0 0 0 0 271684 0 521694 0 673031 427004 +(Pyro-carbamidomethyl)CKPGQIKPH MGYG000002470_01245;MGYG000000196_03974;MGYG000000236_01807;MGYG000000054_03933;MGYG000001661_02666;MGYG000003681_02037;MGYG000001346_01533;MGYG000000098_02017;MGYG000001313_00097;MGYG000000013_02251;MGYG000001780_03476;MGYG000002281_02290 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.8333333333333334 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002470_01245 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 5865546 0 4065926 0 0 4680571 0 0 5272492 0 8623603 0 0 0 5736126 0 3737109 2161985 0 4525546 0 4383708 2612079 5363390 5597794 6170300 0 2172186 0 6816958 0 0 3402509 0 5630430 4467640 5150420 3203321 569588 0 829909 0 442983 530148 0 0 1247449 624754 600851 0 0 0 1005486 0 557245 183946 0 1323988 0 176767 236953 149393 579703 1374633 0 93776 0 683156 0 0 381470 0 1107615 354453 1174558 344215 6999887 0 10029534 0 9055824 7110275 0 0 0 7637081 12862229 0 0 0 6743270 0 5852615 5969227 0 6382948 0 4140571 5096764 7513673 8663874 8725657 0 4568447 0 6629647 0 0 5111278 0 6518944 8815296 8252593 6324314 9521282 0 10640708 0 12015385 8301556 0 0 9192381 13223216 15876202 0 0 0 10229724 0 7807636 5669476 0 7258770 0 7636444 5183178 8524379 9970339 9614019 0 7606561 0 10608346 0 0 10863024 0 10952220 11496582 9628421 9891269 382527 0 307867 0 413136 611420 0 0 1000595 1014936 468715 0 0 0 175557 0 266940 375610 0 315860 0 357573 339950 477463 590009 587914 0 274858 0 942446 0 0 292287 0 309321 434896 510286 333060 +(Pyro-carbamidomethyl)CKPGQIKPHSK MGYG000000236_01807;MGYG000000054_03933;MGYG000001661_02666;MGYG000001346_01533;MGYG000003681_02037;MGYG000001313_00097;MGYG000000098_02017;MGYG000000013_02251;MGYG000001780_03476 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.7777777777777778 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_01807 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 154898 437682 73361 226351 410881 0 303946 0 600273 411281 0 0 0 375794 0 0 0 0 0 500311 40768 194090 0 0 0 0 0 529691 346663 65809 207325 0 286511 0 0 159320 0 0 966808 1353403 670233 974577 771253 0 993719 0 2027885 1210273 0 0 0 385500 0 88333 0 0 0 447187 172492 300032 0 0 0 172194 0 860697 235758 1366999 773524 0 938114 0 0 200592 0 0 2221372 1111260 2128256 1615848 877226 0 1145009 0 2690969 1225426 0 0 0 1412310 0 1148884 0 0 0 1422846 994258 1976791 0 0 0 1236504 0 1130040 1327536 989193 1145677 0 804953 0 0 1659443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121956 83709 0 0 0 0 264235 84424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKPGSVTC(Carbamidomethyl)HHK MGYG000002279_01932;MGYG000001315_01207 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_01932 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 2136216 0 0 1146857 0 0 0 1413243 1812145 1542452 1399785 879212 0 1677092 0 0 1876053 0 0 1160979 0 437613 1686635 0 0 0 0 0 0 0 941129 0 1357270 0 0 1212553 0 0 220683 0 0 142098 0 0 0 206957 0 205285 37831 228546 0 0 0 0 647751 0 0 0 0 136022 234135 0 0 0 0 0 0 0 54344 0 223180 0 0 0 0 0 1182099 0 0 524923 0 0 0 1162131 663850 998951 1376744 1176021 0 1286292 0 0 1105165 0 0 863601 0 406862 1686222 0 0 0 0 0 0 0 1575805 0 371720 0 0 1171273 0 0 739550 0 0 154101 0 0 0 260248 311403 938282 142254 0 0 432575 0 0 327451 0 0 378688 0 111119 468778 0 0 0 0 0 0 0 616348 0 220734 0 0 756108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKPGSVTPHTK MGYG000000802_00776;MGYG000003096_01037;MGYG000004746_00230;MGYG000003274_01474;MGYG000003851_00676;MGYG000000333_00136;MGYG000003266_00392 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CUFV@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000802_00776 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 2775611 786575 0 0 668175 0 0 0 910294 1665107 0 1994972 0 0 2139757 0 0 0 559853 0 983507 0 460952 0 0 0 0 1043626 0 686386 0 523916 0 0 0 0 586574 0 0 0 0 0 0 0 0 0 0 84652 0 0 0 0 0 0 0 0 90443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 537047 501954 0 0 386925 0 0 0 991701 546226 0 1507542 0 0 1577733 0 0 0 1189516 0 694315 0 496755 0 0 0 0 871909 0 391526 0 861095 0 0 0 0 381473 0 1211326 1258039 0 0 943593 0 0 0 1660519 3504680 0 3179253 0 0 4009567 0 0 0 1310393 0 1712833 0 1491715 0 0 0 0 2301874 0 2272200 0 1185969 0 0 0 0 1204091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKQDSATGLYYFDTAK MGYG000000258_01692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Ruminococcus_E|s__Ruminococcus_E bromii_B|m__MGYG000000258 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000258_01692 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 757693 465125 0 0 0 0 700113 0 0 0 445869 0 0 0 0 0 0 0 586358 0 0 0 0 0 726674 0 0 0 0 737649 0 412612 0 0 0 491164 571865 497683 357940 514470 0 0 554705 0 338648 0 0 0 496023 0 0 576602 0 0 0 0 511104 0 461564 0 0 0 376290 442174 0 0 342120 0 0 0 511561 0 0 457377 0 1161167 868238 1103102 0 0 1161071 0 1164364 0 0 0 1233576 0 0 1185577 1219523 0 0 0 875956 0 713668 0 878289 0 1501173 1094527 0 0 1415411 1136316 0 1094431 1434635 0 0 1591122 1296724 1226394 777152 1489252 0 0 1094650 0 1096569 0 0 0 956667 0 0 1216710 1326664 0 0 0 1268805 0 1413054 0 743995 0 1267503 969706 0 0 821315 1574338 0 1047575 1502979 0 0 845033 995426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKTDYEIAWTR MGYG000002528_01048 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0624@1|root,COG0624@2|Bacteria,1TQ0P@1239|Firmicutes,24BF2@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Amidase, hydantoinase carbamoylase family 1.0 - 1.0 - 1.0 3.5.1.6,3.5.1.87 1.0 ko:K06016 1.0 ko00240,ko01100,map00240,map01100 1.0 M00046 1.0 R00905,R04666 1.0 RC00096 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01048 1.0 beta-ureidopropionase. | N-carbamoyl-L-amino-acid hydrolase. N-carbamoyl-L-amino acid amidohydrolase. The animal enzyme also acts on beta-ureidoisobutyrate. | This enzyme, along with EC 3.5.1.77, EC 5.1.99.5 and EC 3.5.2.2, forms part of the reaction cascade known as the 'hydantoinase process', which allows the total conversion of D,L-5-monosubstituted hydantoins into optically pure D- or L-amino acids.-!-The enzyme from Alcaligenes xylosoxidans has broad specificity for carbamoyl-L-amino acids, although it is inactive on the carbamoyl derivatives of glutamate, aspartate, arginine, tyrosine or tryptophan.-!-The enzyme from Sinorhizobium meliloti requires a divalent cation for activity and can hydrolyze N-carbamoyl-L-tryptophan as well as N-carbamoyl L-amino acids with aliphatic substituents.-!-The enzyme is inactive on derivatives of D-amino acids.-!-In addition to N-carbamoyl L-amino acids, the enzyme can also hydrolyze formyl and acetyl derivatives to varying degrees. 3-(carbamoylamino)propanoate + 2 H(+) + H2O = beta-alanine + CO2 + NH4(+). | an N-carbamoyl-L-alpha-amino acid + 2 H(+) + H2O = an L-alpha-amino acid + CO2 + NH4(+). 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K06016:pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87] 1.0 none 1.0 0 0 304067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 836880 0 531033 381341 0 193331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423686 0 375578 0 0 0 0 410039 0 1073190 301244 0 384659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 357138 0 711534 0 0 0 0 304684 0 1337524 411499 0 881619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1417462 0 1182916 0 0 0 0 867617 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKTLDEVK MGYG000000013_03147;MGYG000000243_02465;MGYG000001783_00059;MGYG000000196_04091;MGYG000004876_02408;MGYG000003521_01644;MGYG000004763_01244 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 0.8571428571428571 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_03147 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKTLEEVK MGYG000004797_01413;MGYG000002549_00046;MGYG000002478_01739 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01413 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 1185196 0 1484791 0 2711865 0 0 0 1425392 1784094 2430827 0 4113585 0 0 0 0 0 0 1853495 0 0 0 0 0 1656199 1747238 0 0 1537009 0 0 1825885 0 0 0 2015308 2100002 946496 0 1224904 0 1943876 0 0 0 1077741 1284110 1640730 0 3194884 0 0 0 0 0 0 792356 0 0 0 0 0 1114403 1152799 0 0 877341 0 0 1167701 0 0 0 1128220 1136660 819413 0 1417037 0 2255888 0 0 0 1151197 1315501 1404214 0 3321861 0 0 0 0 0 0 0 0 0 0 0 0 711582 1089624 0 0 0 0 0 847073 0 0 0 0 1172479 1002374 0 497549 0 431343 0 0 0 740873 933847 501562 0 1080812 0 0 0 0 0 0 252199 0 0 0 0 0 955923 465508 0 0 257128 0 0 0 0 0 0 567558 0 431338 0 1236900 0 3367296 0 0 0 1883745 1176178 1801791 0 4197917 0 0 0 0 0 0 1270339 0 0 0 0 0 2718641 0 0 0 2055793 0 0 1211870 0 0 0 2108020 1787325 +(Pyro-carbamidomethyl)CKVGDEVQLL MGYG000001770_01653;MGYG000002293_00521;MGYG000003697_01485 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0050@1|root,COG0050@2|Bacteria,4P1C5@976|Bacteroidetes,2FX1Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001770_01653 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2570974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CKVGDEVQLLGLGEDKK MGYG000001770_01653;MGYG000002293_00521;MGYG000002603_01782;MGYG000003374_00521;MGYG000002080_00527;MGYG000003697_01485 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0050@1|root,COG0050@2|Bacteria,4P1C5@976|Bacteroidetes,2FX1Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001770_01653 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 129450 0 203036 417327 199224 329032 373722 242891 159394 199607 194343 170699 303506 0 145043 0 289193 311333 0 208776 0 223329 350495 165522 465580 538957 0 236662 248751 0 232774 488359 239861 193505 233007 235124 435125 0 231089 0 0 0 0 86284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 201035 0 0 0 0 0 0 0 0 243156 0 0 0 0 331278 0 279670 0 0 247921 0 0 0 0 0 0 0 0 0 0 2583797 0 12155910 2489765 4222638 7316736 2341933 3475176 3057108 2371359 8455709 3184080 4228978 0 3370047 4845646 2108129 11261588 0 2134066 0 7791786 17663026 6053935 2656981 3333928 0 10009376 2120707 0 4024731 4813348 6777651 3416331 4049359 3364547 3216011 6648571 0 0 264996 510832 388723 133632 454352 399006 272423 0 0 132420 0 0 217687 0 0 0 0 536026 0 276826 568182 338479 369096 436410 0 0 0 0 0 163556 0 550528 351368 318294 0 96870 +(Pyro-carbamidomethyl)CLAPLAK MGYG000003589_01892;MGYG000002999_00356;MGYG000004468_00660;MGYG000002540_02142;MGYG000000375_01483;MGYG000004734_01400;MGYG000001783_01519;MGYG000003697_01698;MGYG000002057_00658;MGYG000000390_01195;MGYG000000074_00883;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002834_00628;MGYG000004756_01346;MGYG000002007_00386;MGYG000001692_02867;MGYG000002944_01470;MGYG000001345_01069;MGYG000002438_00285;MGYG000002026_00895;MGYG000003110_00098;MGYG000001562_00044;MGYG000004464_00783;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000000111_00274;MGYG000004536_01441;MGYG000003372_00674;MGYG000001448_01713;MGYG000004779_01244;MGYG000000243_01331;MGYG000002506_01169;MGYG000000273_02725;MGYG000002275_01823;MGYG000003469_01436;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000001334_01647;MGYG000003643_00817;MGYG000004658_00366;MGYG000004479_00217;MGYG000000044_01948;MGYG000003312_01022;MGYG000004526_01607;MGYG000002006_01638;MGYG000001445_01532;MGYG000001749_01249;MGYG000002455_02200;MGYG000001356_02656;MGYG000004487_00117;MGYG000004794_00985;MGYG000001546_00360;MGYG000002494_01669;MGYG000003542_01626;MGYG000000423_01499;MGYG000000421_00908;MGYG000001608_00559;MGYG000000412_01371;MGYG000001489_03093;MGYG000004638_00838;MGYG000000377_02142;MGYG000000445_00706;MGYG000001302.1_00095;MGYG000002556_00846;MGYG000003202_00946;MGYG000004411_00321;MGYG000002095_00148;MGYG000003681_00790;MGYG000000003_00712;MGYG000000097_00328;MGYG000002933_02039;MGYG000004482_00387;MGYG000000196_00479;MGYG000004757_00364;MGYG000001643_00773;MGYG000001661_02632;MGYG000003819_01468;MGYG000002549_00455;MGYG000000467_01930;MGYG000001337_01464;MGYG000002737_00455;MGYG000001789_00244;MGYG000002293_01263;MGYG000003155_00741;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002905_02083;MGYG000000941_01985;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.2872340425531915 976|Bacteroidetes 0.6170212765957447 G 0.6063829787234043 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8723404255319149 gap 0.9468085106382979 - 0.8936170212765957 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9468085106382979 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003589_01892 0.010638297872340425 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 118361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579400 0 0 0 0 528580 0 0 0 457941 129906 0 0 0 0 0 0 0 129921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159780 0 0 0 0 0 0 0 0 0 329838 0 0 0 0 0 0 0 0 0 136287 0 0 374376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101017 0 0 0 0 0 0 0 0 0 0 0 0 0 273598 0 0 0 0 0 613824 0 0 1052884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2406692 0 0 0 0 0 0 0 0 0 2417322 0 0 0 1014698 1200771 0 0 0 0 997652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290631 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CLAPMADALNK MGYG000003694_01737;MGYG000002974_01418;MGYG000001683_01827;MGYG000003374_01118;MGYG000000271_03250;MGYG000001319_00348;MGYG000000262_01195;MGYG000000404_00344;MGYG000003812_01036;MGYG000002517_01026;MGYG000000153_00303;MGYG000001652_01009;MGYG000000489_00503;MGYG000001299_00204;MGYG000001439_00571;MGYG000004707_01697;MGYG000000077_00219 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6470588235294118 186801|Clostridia 0.8235294117647058 G 0.8235294117647058 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7647058823529411 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.058823529411764705 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 120167 0 140525 220426 272513 0 0 370024 387810 430593 0 0 0 350057 521278 189367 348899 0 452299 448052 0 0 0 0 0 364997 325259 0 0 329982 0 0 157200 0 0 0 277755 212704 0 0 0 69539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199909 0 312284 230094 122971 0 0 0 164493 0 0 0 0 0 361299 168179 180478 0 193952 306762 0 0 0 0 0 0 154994 0 0 435219 0 0 370015 0 0 0 170019 438318 1199585 0 676975 2887737 1100570 0 0 1551981 1995381 1296308 0 0 0 1833694 1784180 1458635 1865386 0 1691565 1952187 0 0 0 0 0 1243426 1928082 0 0 1649261 0 0 848980 0 0 0 1687706 853771 377327 0 232213 0 232086 0 0 139788 154516 442840 0 0 0 561404 485999 207594 449715 0 368552 349665 0 0 0 0 0 375029 330087 0 0 203071 0 0 135166 0 0 0 396857 327115 +(Pyro-carbamidomethyl)CLGGFEEGIHVSR MGYG000000262_02240 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,25VHE@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02240 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 248840 389672 0 292827 0 256917 0 255326 0 400392 0 0 400940 0 276759 462255 0 0 0 0 0 257905 0 0 0 0 0 0 0 295576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134990 173887 0 0 0 166617 0 0 0 0 189905 0 188089 0 1782468 1403324 0 2015717 0 1333105 0 1264828 0 1167072 0 0 1055971 0 1756744 1173178 0 0 0 0 0 2117571 0 291169 1487783 1651074 1694211 0 0 1123752 0 0 0 0 1650339 0 1093285 0 0 141616 0 212136 0 0 0 0 0 295913 0 0 320712 0 0 579350 0 0 0 0 0 230387 0 0 139643 0 228518 0 0 0 0 0 0 0 0 0 0 0 0 244280 0 226457 0 471533 0 167712 0 0 0 0 165409 0 334816 452877 0 0 0 0 0 441508 0 352311 97907 153429 0 0 0 197287 0 0 0 0 174606 0 352188 0 +(Pyro-carbamidomethyl)CLGVDDRK MGYG000001683_00453 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Frisingicoccus|s__|m__MGYG000001683 1.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,27J24@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Amidohydrolase family 1.0 nagA 1.0 - 1.0 3.5.1.25 1.0 ko:K01443 1.0 ko00520,ko01130,map00520,map01130 1.0 - 1.0 R02059 1.0 RC00166,RC00300 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_1 1.0 - 1.0 CE9 1.0 CE9 1.0 CE9 1.0 MGYG000001683_00453 1.0 N-acetylglucosamine-6-phosphate deacetylase. - Formerly EC 3.5.1.80. H2O + N-acetyl-D-glucosamine 6-phosphate = acetate + D-glucosamine 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 K01443:nagA, AMDHD2; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CLIITGAGEK MGYG000001315_01870;MGYG000000262_02232;MGYG000000077_02465 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,25UX1@186806|Eubacteriaceae 0.6666666666666666 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.6666666666666666 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01870 0.3333333333333333 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 479192 0 235283 137172 0 0 0 0 0 271483 0 0 0 202380 700444 0 225570 0 583719 697050 568972 0 0 0 751137 546486 205078 0 0 197725 0 0 139353 612952 489138 0 327311 0 204465 0 118385 673623 0 0 444571 0 0 382703 0 0 0 400173 507939 0 370309 0 202252 1079119 449816 0 0 0 587714 216326 624352 0 0 710324 0 0 102428 632287 346544 0 525377 0 3005012 0 678758 4738865 0 0 819972 0 0 2495872 0 0 0 2302308 3144659 0 2131085 0 2722197 2756355 1824012 0 0 0 3415279 2795111 3401548 0 0 1738572 0 0 1623369 3452101 3245772 0 2319342 661722 893809 0 690272 0 0 0 1203387 0 0 1055415 0 0 0 966395 780315 0 1345170 0 683030 1328874 258736 0 0 0 563771 481630 886383 0 0 700746 0 0 1018161 209114 818221 0 551390 827731 168238 0 727710 328171 0 0 416658 0 0 326784 0 0 0 421499 261503 0 242375 0 354555 0 469599 0 0 0 359019 209377 238393 0 0 84526 0 0 1298100 342561 346494 0 179870 559960 +(Pyro-carbamidomethyl)CLILTGAGEK MGYG000001315_01870;MGYG000003311_01584;MGYG000000262_02232;MGYG000000077_02465;MGYG000001777_01056;MGYG000001319_02237 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,27IZZ@186928|unclassified Lachnospiraceae 0.3333333333333333 186801|Clostridia 1.0 I 1.0 Enoyl-CoA hydratase/isomerase 0.5 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01870 0.16666666666666666 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 213147 0 0 0 0 0 729976 652499 0 0 0 0 984260 0 0 0 0 0 0 0 381442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 861378 0 542851 0 0 0 746619 0 0 368188 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 847555 0 0 0 0 0 0 0 3175217 0 0 0 0 0 2850974 0 0 0 0 0 0 0 0 0 0 0 0 0 3803619 0 0 0 0 0 0 0 0 0 2415266 0 0 0 0 0 0 0 0 0 1370001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CLITALSELNQPR MGYG000002934_01790;MGYG000000404_01798;MGYG000002517_00543 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.6666666666666666 186801|Clostridia 0.6666666666666666 C 1.0 electron transfer flavoprotein 0.6666666666666666 etfB 1.0 - 0.6666666666666666 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002934_01790 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 228781 0 528705 121993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99359 0 0 0 0 0 0 363414 0 0 0 0 0 213178 0 197152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164115 0 0 0 3036456 0 155288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1661751 0 0 0 5454047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7313742 0 0 0 0 0 0 0 0 0 0 3014047 0 12628995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6998271 0 0 0 0 0 0 0 0 0 0 16041173 20936132 +(Pyro-carbamidomethyl)CLLNQEDIMDGKK MGYG000001346_00649;MGYG000000243_02465;MGYG000003367_01580;MGYG000004876_02408;MGYG000000029_01191;MGYG000004797_01413;MGYG000002438_01052;MGYG000002478_01739 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 0.875 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_00649 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 545000 0 0 0 0 0 0 0 0 0 1358327 0 0 1434675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1026553 0 0 0 0 743399 0 0 321890 0 0 0 0 0 0 0 0 0 466292 0 0 320895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468535 0 0 0 0 0 0 0 336811 0 0 0 0 0 0 0 0 0 903608 0 0 720608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519155 0 0 0 0 381615 0 0 510534 0 0 0 0 0 0 0 0 0 783355 0 0 672460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407299 0 0 0 0 462927 0 0 355251 0 0 0 0 0 0 0 0 0 1165392 0 0 772764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CLLYAINGGKDEK MGYG000000251_01975;MGYG000000417_02137;MGYG000003702_02236;MGYG000004039_00572;MGYG000000018_02208;MGYG000000217_01657;MGYG000000231_00514 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,27J0U@186928|unclassified Lachnospiraceae 0.5714285714285714 186801|Clostridia 1.0 C 1.0 Pyruvate formate lyase-like 0.5714285714285714 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_01975 0.14285714285714285 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2508198 0 0 0 0 2115784 0 0 0 0 2283283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 631531 0 0 0 0 965612 0 0 0 0 754690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421755 0 0 0 0 633245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 819370 0 0 0 0 597914 0 0 0 0 302751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331316 0 0 0 0 493850 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CLPGSVADDRK MGYG000004464_00921;MGYG000000196_00899;MGYG000004763_01967;MGYG000004493_00376;MGYG000000045_01847;MGYG000001415_02505;MGYG000004797_02907;MGYG000001423_03082;MGYG000000479_02090;MGYG000001925_01569;MGYG000001346_01121;MGYG000000215_01600;MGYG000002478_02896 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.46153846153846156 976|Bacteroidetes 0.6923076923076923 S 1.0 Psort location Cytoplasmic, score 8.96 0.6153846153846154 - 0.9230769230769231 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004464_00921 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 2368328 0 0 0 1521131 0 0 0 1687583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 778930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CLQEAQAQR MGYG000001783_01717;MGYG000000029_01548;MGYG000003681_00508;MGYG000003701_03757;MGYG000001364_03472;MGYG000001346_01330;MGYG000003312_02085;MGYG000004185_00718;MGYG000000054_03790;MGYG000002275_00363;MGYG000002478_01473;MGYG000004797_02540;MGYG000003252_02925;MGYG000001489_04121;MGYG000000013_01585;MGYG000000196_02857;MGYG000004757_01054;MGYG000004571_00850;MGYG000000236_02278;MGYG000000243_01844;MGYG000001345_00716;MGYG000002549_02435;MGYG000001461_03704;MGYG000001599_01758;MGYG000003922_02564;MGYG000002438_03363;MGYG000001313_02809;MGYG000000174_02073 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FN0E@200643|Bacteroidia,4AN4E@815|Bacteroidaceae 0.6071428571428571 976|Bacteroidetes 1.0 H 1.0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA 1.0 kbl 1.0 - 1.0 2.3.1.29 1.0 ko:K00639 1.0 ko00260,map00260 1.0 - 1.0 R00371 1.0 RC00004,RC00394 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001783_01717 0.03571428571428571 glycine C-acetyltransferase. 2-amino-3-ketobutyrate coenzyme A ligase. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism 1.0 K00639:kbl, GCAT; glycine C-acetyltransferase [EC:2.3.1.29] 1.0 none 1.0 1180243 1620779 2470779 1410032 1312226 1186012 1169438 1599548 1012951 839307 922365 1546448 1480961 1379096 1421422 1332199 1431515 808856 1130022 303569 1413212 1536626 1020929 2301058 0 1241832 1656549 1290546 1385581 1699860 2646672 1514995 3067088 1455741 1644550 1211180 1693467 2190046 1261306 943652 1599988 1727152 1480478 1292017 1296672 1515806 1615606 1791994 1567706 1704897 1467583 1644313 1869277 1554443 1160153 929531 1480275 1286984 1403281 1411447 1704935 1037109 0 1283241 1449410 1436646 1096932 1650220 1032121 1465429 1429922 1349640 1671452 1221036 1294524 1363478 1074100 1176334 1225432 1864577 1777983 1365389 1418603 1098463 1169041 1121341 1295896 1105530 634973 1180614 993416 1322353 1153589 2036619 1213777 955502 826345 701751 1540551 1754032 0 1500229 1103739 1522899 1407448 961464 1382233 1208179 1373307 705442 1467458 1627242 1246501 1265606 0 0 224525 0 0 0 0 0 0 0 348246 427573 547563 0 0 0 0 0 0 0 874573 0 217408 225864 0 0 0 0 0 0 0 0 0 658709 0 0 0 0 0 0 249598 471205 111511 924398 936016 986568 1191960 551767 926292 485419 1153975 1030933 0 824971 669954 1495343 672792 998076 826520 774543 1378751 1382295 0 739994 597758 1188154 0 1630430 966375 1310571 603824 1041840 413823 721159 1325297 976102 +(Pyro-carbamidomethyl)CLSAGSNESHSAIIAR MGYG000002494_03341 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1080@1|root,COG1925@1|root,COG3412@1|root,COG1080@2|Bacteria,COG1925@2|Bacteria,COG3412@2|Bacteria,1MUT8@1224|Proteobacteria,1RRCZ@1236|Gammaproteobacteria,3WVVD@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 PEP-utilising enzyme, N-terminal 1.0 dhaM 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006476,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033554,GO:0033558,GO:0034983,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0047324,GO:0050896,GO:0051716,GO:0071704,GO:0098732,GO:0140096,GO:1901564 1.0 2.7.1.121 1.0 ko:K05881 1.0 ko00561,map00561 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000,ko02000 1.0 - 1.0 - 1.0 iECs_1301.ECs1703,iSF_1195.SF1201,iS_1188.S1285,iUTI89_1310.UTI89_C1391,iZ_1308.Z1969 1.0 EIIA-man,PEP-utilisers_N,PEP-utilizers,PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03341 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism 1.0 K05881:dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330930 0 0 0 0 260469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CLSC(Carbamidomethyl)FAC(Carbamidomethyl)VER MGYG000001338_01863;MGYG000001689_04268;MGYG000004735_02511;MGYG000000142_01113;MGYG000000216_03384;MGYG000000184_02633;MGYG000000201_01324;MGYG000002989_01366;MGYG000002042_01111;MGYG000000806_00466;MGYG000000251_01182;MGYG000000050_02100 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1150@1|root,COG1150@2|Bacteria,1V27J@1239|Firmicutes,24FU5@186801|Clostridia,3Y1I7@572511|Blautia 0.3333333333333333 186801|Clostridia 0.75 C 0.8333333333333334 4Fe-4S dicluster domain 0.5833333333333334 - 1.0 - 1.0 - 0.6666666666666666 - 0.5 - 0.9166666666666666 - 0.9166666666666666 - 0.6666666666666666 - 0.9166666666666666 - 0.5 - 0.8333333333333334 - 1.0 - 1.0 Fer4_10,Fer4_8 0.4166666666666667 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01863 0.08333333333333333 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 - 0.9166666666666666 - 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 700610 912146 0 0 0 0 444306 +(Pyro-carbamidomethyl)CLTADEAANAPESTK MGYG000001627_00502;MGYG000003937_00374 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001627_00502 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 765062 0 0 0 0 0 0 0 0 0 468329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CLVDIARK MGYG000000179_03143 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,26889@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Arginosuccinate synthase 1.0 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03143 1.0 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids|Fluid shear stress and atherosclerosis 1.0 K01940:argG, ASS1; argininosuccinate synthase [EC:6.3.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 404372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 171872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907057 0 1491845 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CLVEGAIENSYTK MGYG000000223_01696 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG1486@1|root,COG1486@2|Bacteria,2GK80@201174|Actinobacteria,4CV7D@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 Family 4 glycosyl hydrolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_4,Glyco_hydro_4C 1.0 3.2.1.122 1.0 GH4 1.0 GH4 1.0 GH4 1.0 MGYG000000223_01696 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 713252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 315995 0 0 0 0 0 0 0 1305871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 626980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CMDAAAHVR MGYG000000077_00330 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum soehngenii|m__MGYG000000077 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 534677 0 0 0 1012309 0 0 0 671551 0 0 0 0 0 648607 0 0 0 0 0 1014888 0 0 0 0 0 0 206979 0 0 0 0 0 0 0 0 0 0 890541 0 997461 0 719173 1661928 0 0 599975 0 0 0 0 0 0 0 0 0 0 0 348825 0 855948 0 0 0 0 1385934 0 0 0 0 0 0 0 0 0 0 2408897 0 3703762 0 2591067 714345 0 0 1863874 0 0 0 0 0 2006707 0 0 0 0 0 3612803 0 1399712 0 0 0 0 408114 0 0 0 0 0 0 0 0 0 0 5125429 0 4127194 0 5451393 4445793 0 0 7678038 0 0 0 0 0 6803081 0 0 0 0 0 5604590 0 4828540 0 0 0 0 5184512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CMGANQQQYLK MGYG000002485_01479 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,378RN@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002485_01479 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 538373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CNIGTIGHVDHGK MGYG000001615_01716;MGYG000000171_02844;MGYG000002279_01932;MGYG000000201_03875;MGYG000000245_03248;MGYG000001688_04229;MGYG000000280_01200;MGYG000001714_01291;MGYG000000198_01165;MGYG000000271_03365;MGYG000004804_01395;MGYG000001315_01207;MGYG000000133_02991;MGYG000001602_02247;MGYG000001310_01963;MGYG000003273_00234;MGYG000000140_01590;MGYG000001065_02730;MGYG000002528_01098;MGYG000002609_01147;MGYG000002202_00030;MGYG000000179_00920;MGYG000000216_02406;MGYG000000217_01428;MGYG000002517_00205;MGYG000002290_01325;MGYG000001531_00906;MGYG000004296_01668;MGYG000001607_01045;MGYG000001141_02439;MGYG000001652_01300;MGYG000000127_03982;MGYG000003425_03741;MGYG000000251_00064;MGYG000001338_03373;MGYG000002670_00364;MGYG000000139_00697;MGYG000000233_00807;MGYG000000142_00171;MGYG000000255_02009;MGYG000000404_00531;MGYG000004087_00551;MGYG000000242_00282;MGYG000000018_00453;MGYG000000187_02029;MGYG000000202_03457;MGYG000001606_01669;MGYG000000212_03313;MGYG000001698_04050;MGYG000004558_00415;MGYG000000032_01232;MGYG000001777_01732;MGYG000002837_02416;MGYG000000193_02083;MGYG000000445_01370;MGYG000002212_00196;MGYG000000249_00026;MGYG000004799_01385;MGYG000004630_01824;MGYG000002286_02469;MGYG000001814_01592;MGYG000000262_00030;MGYG000002772_01895;MGYG000002492_00344;MGYG000001617_01406;MGYG000003514_00785;MGYG000002052_00232;MGYG000003013_00349;MGYG000000206_00901;MGYG000004733_01211;MGYG000001319_01764 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 0.2535211267605634 186801|Clostridia 0.9577464788732394 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9859154929577465 tuf 1.0 - 0.971830985915493 - 1.0 ko:K02358 0.9859154929577465 - 0.9859154929577465 - 0.9859154929577465 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9859154929577465 - 0.9859154929577465 - 1.0 - 0.9859154929577465 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001615_01716 0.014084507042253521 - - - - 1.0 1.0 1.0 1.0 - 0.9859154929577465 K02358:tuf, TUFM; elongation factor Tu 0.9859154929577465 none 1.0 0 312121 430402 355920 748856 380431 219923 0 0 640556 0 0 340715 0 1918560 492928 338263 1777344 239510 931890 0 653667 694134 129710 0 0 0 1126744 526548 0 155778 499829 220565 0 0 0 0 296219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 202234 175696 208757 0 238867 211400 0 0 214254 0 0 213780 0 324083 0 183904 0 293800 140905 0 219736 0 113117 0 0 0 0 188443 0 205384 185348 244533 0 0 0 0 294900 0 3063411 1837412 2400795 2191377 1817668 1802763 0 0 2334836 0 0 1344318 0 1950460 2559000 3032616 1478841 1986098 2844467 0 1764078 1063521 1851395 0 0 0 3346435 3724025 0 3557461 1788718 2251286 0 0 0 0 3287018 0 0 0 308861 0 0 303271 0 0 424815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157352 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CNVGDTVKR MGYG000002438_00415 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG4770@1|root,COG4770@2|Bacteria,4NSWV@976|Bacteroidetes,2FRYI@200643|Bacteroidia,22YBV@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Biofilm PGA synthesis protein PgaD 1.0 mmdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00415 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1081097 0 0 0 0 0 0 0 0 1974143 0 0 0 0 206311 0 0 0 347383 0 0 0 0 0 0 442340 0 303844 0 0 0 0 0 0 0 0 0 0 356207 0 0 0 0 0 0 0 0 665852 0 0 0 0 294661 0 0 0 469924 0 0 0 0 0 0 271965 0 136878 0 0 0 0 0 0 354943 0 0 0 687567 0 0 0 0 0 0 0 0 1782109 0 0 0 0 513736 0 0 0 652047 0 0 0 0 0 0 327659 0 1092203 0 0 0 0 0 0 1174992 0 0 0 2344709 0 0 0 0 0 0 0 0 2636796 0 0 0 0 1392959 0 0 0 3465620 0 0 0 0 0 0 1569138 0 +(Pyro-carbamidomethyl)CNYEAVKER MGYG000000179_05289 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248IC@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Glycosyl hydrolases family 31 1.0 yicI 1.0 - 1.0 3.2.1.177,3.2.1.199 1.0 ko:K01811,ko:K15922 1.0 - 1.0 - 1.0 R00802,R11543 1.0 RC00028,RC00059,RC00077,RC00451 1.0 ko00000,ko01000 1.0 - 1.0 GH31 1.0 - 1.0 Glyco_hydro_31 1.0 - 1.0 GH31 1.0 GH31 1.0 GH31 1.0 MGYG000000179_05289 1.0 alpha-D-xyloside xylohydrolase. | sulfoquinovosidase. alpha-xylosidase. The enzyme catalyzes hydrolysis of a terminal, unsubstituted xyloside at the extreme reducing end of a xylogluco-oligosaccharide.-!-Representative alpha-xylosidases from glycoside hydrolase family 31 utilize a two-step (double-displacement) mechanism involving a covalent glycosyl-enzyme intermediate, and retain the anomeric configuration of the product. | The enzyme, characterized from the bacteria Escherichia coli and Pseudomonas putida, hydrolyzes terminal non-reducing alpha- sulfoquinovoside residues in alpha-sulfoquinovosyl diacylglycerides and alpha-sulfoquinovosyl glycerol. Hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose. | a 6-sulfo-alpha-D-quinovosyldiacylglycerol + H2O = 6-sulfo-alpha-D- quinovose + a 1,2-diacyl-sn-glycerol. 1.0 1.0 1.0 1.0 - 1.0 K01811:xylS, yicI; alpha-D-xyloside xylohydrolase [EC:3.2.1.177]|K15922:yihQ; sulfoquinovosidase [EC:3.2.1.199] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290557 0 0 0 0 0 0 0 0 958345 0 0 0 0 0 0 0 1146699 1410962 0 1081003 0 942075 1019059 0 715861 0 958732 737576 1244978 0 0 0 0 1544287 944396 0 0 867419 0 0 0 742042 0 942727 1281800 0 +(Pyro-carbamidomethyl)CPAGISHPMVGLLAR MGYG000000142_01107;MGYG000002298_01727;MGYG000001652_00112;MGYG000004201_01235;MGYG000000200_00050;MGYG000001698_00113;MGYG000000031_01423;MGYG000004839_00388;MGYG000000194_00425;MGYG000003335_01021;MGYG000002202_00763;MGYG000002946_00022;MGYG000004296_00035;MGYG000000184_02627;MGYG000001338_01870;MGYG000001689_04274;MGYG000004735_02505;MGYG000000216_03378;MGYG000004733_00383;MGYG000002989_01360;MGYG000000140_03070 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia 0.47619047619047616 186801|Clostridia 1.0 C 0.8095238095238095 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein 0.47619047619047616 - 1.0 - 1.0 - 0.5238095238095238 - 0.5238095238095238 - 0.5238095238095238 - 0.5238095238095238 - 0.5238095238095238 - 0.5238095238095238 - 0.5238095238095238 - 1.0 - 1.0 - 1.0 FAD_binding_2,Fer4,Fer4_10,Fer4_7,Pyr_redox_2 0.47619047619047616 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01107 0.047619047619047616 - - - - 0.5238095238095238 0.5238095238095238 0.5238095238095238 0.5238095238095238 - 0.5238095238095238 - 0.5238095238095238 none 1.0 0 1508162 1269838 0 1775344 0 0 0 0 0 1467143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762364 1762631 845040 0 0 0 0 1003624 0 2676878 472668 0 1154858 0 0 0 0 0 1139435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3091039 819234 613911 0 0 0 0 728897 0 2987826 620550 0 287623 0 0 0 0 0 236320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742811 2024002 1032638 0 0 0 0 593592 0 827899 264172 0 575281 0 0 0 0 0 256290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577716 680900 0 0 0 0 0 0 0 4868600 3007437 0 1178333 0 0 0 0 0 1521492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3924077 5680239 4733206 0 0 0 0 2757271 +(Pyro-carbamidomethyl)CPGSDEFTLVNANTGK MGYG000001302.1_01986 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_01986 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391242 1169332 0 0 456454 749337 564328 0 0 0 781563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475439 655272 0 0 0 0 0 0 0 0 0 0 0 888972 825154 0 0 545235 833860 600028 0 0 0 719444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388319 370667 0 0 0 0 0 0 0 0 0 0 0 544866 787258 0 0 0 1297796 0 0 0 0 425220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 598788 0 0 0 0 0 0 0 0 0 0 0 800485 555147 0 0 0 889968 346546 0 0 0 758940 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CPLPGTVLSVK MGYG000000074_02437;MGYG000000003_01112 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG4770@1|root,COG4770@2|Bacteria,4NSWV@976|Bacteroidetes,2FRYI@200643|Bacteroidia,22UGJ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Biotin-requiring enzyme 1.0 mmdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02437 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 114973 0 0 0 0 0 0 0 0 0 83265 0 0 0 0 0 0 157184 0 0 0 0 0 0 0 0 0 386891 0 0 111674 0 0 0 0 0 0 0 245052 0 0 0 0 0 0 0 0 0 77681 0 0 0 0 0 0 357608 0 0 0 0 0 0 0 0 0 177351 0 0 139678 0 0 0 0 339659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80066 0 0 0 0 0 0 0 0 0 0 694486 0 0 0 0 0 0 0 0 0 1012239 0 0 0 0 0 0 1507619 0 0 0 0 0 0 0 0 0 1683504 0 0 286114 0 0 0 0 794904 +(Pyro-carbamidomethyl)CPNHVEVSHIR MGYG000001300_01521;MGYG000003166_01563 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,3WH9C@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 DAK2 domain fusion protein YloV 1.0 - 1.0 - 1.0 - 1.0 ko:K07030 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Dak1_2,Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_01521 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07030:fakA; fatty acid kinase [EC:2.7.2.18] 1.0 none 1.0 200719 0 0 0 0 0 139559 0 0 0 305891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478857 0 0 0 0 0 0 0 0 0 0 375388 0 901265 0 0 0 0 0 1304528 0 0 0 852490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1132522 0 0 0 0 0 0 0 0 0 0 1105191 0 0 0 0 0 0 0 414053 0 0 0 281899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284653 0 0 0 0 0 0 0 0 0 0 282054 0 533924 0 0 0 0 0 852040 0 0 0 592384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476382 0 0 0 0 0 0 0 0 0 0 524052 0 94361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361352 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CPTAHIDRK MGYG000002492_01293 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase 1.0 efp 1.0 - 1.0 - 1.0 ko:K02356 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 EFP,EFP_N,Elong-fact-P_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01293 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02356:efp; elongation factor P 1.0 none 1.0 0 0 63956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86807 0 0 0 0 0 0 0 446466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253133 0 0 0 0 235780 0 0 2144334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2213239 0 0 0 0 2391957 0 0 371809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 510649 0 0 0 0 692875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CPTQIHNFATDDELK MGYG000001338_01046 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG4656@1|root,COG4656@2|Bacteria,1TS9H@1239|Firmicutes,24DQ7@186801|Clostridia,3XYYU@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Methylene-tetrahydrofolate reductase C terminal 1.0 metV 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 iHN637.CLJU_RS18525 1.0 MTHFR_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01046 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 453300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 597923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 954354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CPVYQNVDALPHTDPAEIK MGYG000004797_03294;MGYG000004876_02965;MGYG000002171_00714;MGYG000004720_00652;MGYG000000196_04611;MGYG000004823_01134;MGYG000000243_00899;MGYG000001345_02939;MGYG000000013_03230;MGYG000002560_01276 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia,4AK7G@815|Bacteroidaceae 0.9 976|Bacteroidetes 1.0 I 1.0 malonyl CoA-acyl carrier protein transacylase 1.0 fabD 1.0 - 1.0 2.3.1.39 1.0 ko:K00645 1.0 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 1.0 M00082 1.0 R01626,R11671 1.0 RC00004,RC00039,RC02727 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 Acyl_transf_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_03294 0.1 [acyl-carrier-protein] S-malonyltransferase. MCAT. Essential, along with EC 2.3.1.38, for the initiation of fatty-acid biosynthesis in bacteria.-!-Also provides the malonyl groups for polyketide biosynthesis.-!-The product of the reaction, malonyl-ACP, is an elongation substrate in fatty-acid biosynthesis.-!-In Mycobacterium tuberculosis, holo-ACP (the product of EC 2.7.8.7) is the preferred substrate.-!-This enzyme also forms part of the multienzyme complexes EC 4.1.1.88 and EC 4.1.1.89.-!-Malonylation of ACP is immediately followed by decarboxylation within the malonate-decarboxylase complex to yield acetyl-ACP, the catalytically active species of the decarboxylase.-!-In the enzyme from Klebsiella pneumoniae, methylmalonyl-CoA can also act as a substrate but acetyl-CoA cannot whereas the enzyme from Pseudomonas putida can use both as substrates.-!-The ACP subunit found in fatty-acid biosynthesis contains a pantetheine-4'-phosphate cofactor; that from malonate decarboxylase also contains pantetheine-4'-phosphate but in the form of a 2'-(5-triphosphoribosyl)-3'-dephospho-CoA cofactor. holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis|Prodigiosin biosynthesis|Metabolic pathways|Fatty acid metabolism 1.0 K00645:fabD, MCAT, MCT1; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] 1.0 none 1.0 0 0 1468648 0 0 0 0 0 0 0 0 0 1515772 0 0 1425166 0 0 0 706829 0 0 0 0 0 0 0 0 0 901478 0 0 1675618 0 0 0 0 1386469 0 0 488112 0 0 0 0 0 0 0 0 0 1255840 0 0 1085958 0 0 0 229670 0 0 0 0 0 0 0 0 0 769015 0 0 524437 0 0 0 0 595991 0 0 501998 0 0 0 0 0 0 0 0 0 731677 0 0 398983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141341 0 0 0 0 0 0 453748 0 0 0 0 0 0 0 0 0 639940 0 0 0 0 0 0 0 349338 +(Pyro-carbamidomethyl)CQAGFC(Carbamidomethyl)SPR MGYG000002298_00538;MGYG000000038_01495;MGYG000002993_00207;MGYG000000404_00180;MGYG000004552_00557;MGYG000001619_01503;MGYG000002312_03079;MGYG000000255_01681;MGYG000001186_01771;MGYG000000164_01752;MGYG000000271_03444;MGYG000001683_00852;MGYG000002517_00257;MGYG000002036_00234;MGYG000001627_02087;MGYG000002517_00473;MGYG000002059_01429;MGYG000000489_00238;MGYG000000154_01590;MGYG000000153_02080;MGYG000000076_01007;MGYG000000245_01076;MGYG000000205_00110;MGYG000003074_00570;MGYG000000127_02775;MGYG000002279_02522;MGYG000001315_01114;MGYG000004271_01228;MGYG000000212_00378;MGYG000002105_01104 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 0.3333333333333333 186801|Clostridia 0.9666666666666667 S 0.4666666666666667 FAD dependent oxidoreductase 0.5 - 1.0 - 1.0 1.1.5.3 0.9666666666666667 ko:K00111 0.9666666666666667 ko00564,ko01110,map00564,map01110 0.9666666666666667 - 1.0 R00848 0.9666666666666667 RC00029 0.9666666666666667 ko00000,ko00001,ko01000 0.9666666666666667 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 0.9666666666666667 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_00538 0.03333333333333333 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 0.9666666666666667 0.9666666666666667 0.9666666666666667 0.9666666666666667 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 0.9666666666666667 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 0.9666666666666667 none 1.0 1733066 1054860 1029240 1259332 1454658 1454285 1598919 2248693 2197284 2358474 1413524 1763756 1488935 1480309 2158529 1369047 1436701 0 2109025 2257880 1742384 1216178 0 628124 2413241 1972213 1662345 0 1453468 1848562 570522 783547 681628 1408028 1887809 1363889 1402404 774764 518183 552966 219983 607738 363362 229258 559328 461195 342456 461998 306744 236371 140849 365749 380866 265874 335648 0 635166 543026 381380 0 0 519874 552747 410093 446661 0 733906 376138 469951 448698 356664 584406 443989 417261 385676 359217 503428 0 0 317819 0 0 344778 501434 0 349187 0 253572 0 364740 448684 0 259213 0 488826 767767 0 0 0 0 496440 559412 444501 0 164667 404420 0 152612 295872 388313 459168 419494 525530 0 2253708 327350 491478 1893893 897096 676406 1167057 2347134 2507969 1260607 717447 1023385 625330 2288577 2376621 866817 1536399 0 2101320 2042184 1439190 0 0 0 3078984 2104130 2363391 0 627234 1814005 442823 917931 617446 1332749 2231768 2360334 2169111 549128 1604080 969974 1891072 329853 1066518 1774959 2083827 1492198 1900516 2859389 1823396 1841167 749309 2731188 2286811 1079200 1744666 0 1942320 1186721 1658090 1086454 0 1430452 2689726 1972758 2370641 0 702929 1378124 1519133 546493 2087867 2353191 1829647 3180123 3254903 2071569 +(Pyro-carbamidomethyl)CQAGFC(Carbamidomethyl)TPR MGYG000001564_01807;MGYG000000077_00890;MGYG000004691_01133;MGYG000002445_00671;MGYG000002946_03411;MGYG000001199_03274;MGYG000001493_05221;MGYG000001622_01941;MGYG000002912_01338;MGYG000000179_02173;MGYG000000233_01585;MGYG000001311_02981;MGYG000000262_00167;MGYG000000198_04022 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,21XTX@1506553|Lachnoclostridium 0.5714285714285714 186801|Clostridia 1.0 S 0.5714285714285714 FAD dependent oxidoreductase 0.8571428571428571 lhgO 0.42857142857142855 - 1.0 1.1.5.3 0.8571428571428571 ko:K00111 0.8571428571428571 ko00564,ko01110,map00564,map01110 0.8571428571428571 - 0.8571428571428571 R00848 0.8571428571428571 RC00029 0.8571428571428571 ko00000,ko00001,ko01000 0.8571428571428571 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001564_01807 0.07142857142857142 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 0.8571428571428571 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 0.8571428571428571 none 1.0 930621 0 0 721109 0 404507 0 0 744546 779029 0 0 0 885914 940858 320888 451748 0 0 1166941 0 499859 0 288856 0 776280 653434 0 852303 862454 0 0 0 0 795196 748687 917885 0 443939 0 0 581864 0 230347 0 0 533293 470319 0 0 0 408313 433072 90894 100551 0 0 514481 0 90392 0 291228 0 431156 566633 0 506348 351017 0 0 0 0 524984 465770 470299 0 1482795 0 0 1302685 0 490193 0 0 808966 889999 0 0 0 1026411 1301391 851756 1058051 0 0 1427409 0 1060807 0 372195 0 1081417 1384293 0 920920 1049009 0 0 0 0 641821 853466 773880 0 386831 0 0 465408 0 411463 0 0 440402 600111 0 0 0 388682 253975 362977 466031 0 0 446982 0 335994 0 0 0 265645 430818 0 330179 273825 0 0 0 0 259775 329855 281455 0 1634971 0 0 1321847 0 734014 0 0 1497510 1321643 0 0 0 2341048 1609213 541478 1281515 0 0 1315511 0 833848 0 1049002 0 1560474 1625140 0 1771650 894429 0 0 0 0 654902 1432815 1738722 0 +(Pyro-carbamidomethyl)CQDILKK MGYG000002478_02197 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 MGYG000002478_02197 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1332186 0 326401 0 0 0 0 271240 0 0 0 0 299481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 700058 0 239322 0 0 0 0 481056 0 0 0 0 335835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 565131 0 314050 0 0 0 0 304749 0 0 0 0 305699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1229704 0 1345091 0 0 0 0 1059905 0 0 0 0 678944 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CQDTGTAIIHGEK MGYG000000215_02049;MGYG000002293_01379;MGYG000003697_00235;MGYG000003493_01720 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,4NE85@976|Bacteroidetes,2FNPE@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Catalyzes the reversible hydration of fumarate to (S)- malate 1.0 fumB 1.0 - 1.0 4.2.1.2 1.0 ko:K01676 1.0 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00374 1.0 R01082 1.0 RC00443 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fumerase,Fumerase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000215_02049 0.25 fumarate hydratase. fumarase. - (S)-malate = fumarate + H2O. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01676:E4.2.1.2A, fumA, fumB; fumarate hydratase, class I [EC:4.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2518551 0 0 0 0 2410564 0 0 0 0 2083595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CQETGITIER MGYG000002494_03339 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2376@1|root,COG2376@2|Bacteria,1MVSR@1224|Proteobacteria,1RNRQ@1236|Gammaproteobacteria,3WVUW@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Dak1 domain 1.0 dhaK 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 1.0 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 1.0 ko:K00863,ko:K05878 1.0 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 1.0 M00344 1.0 R01011,R01012,R01059 1.0 RC00002,RC00015,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 1.0 Dak1,Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03339 1.0 phosphoenolpyruvate--glycerone phosphotransferase. | triokinase. | glycerone kinase. | FAD-AMP lyase (cyclizing). triose kinase. | dihydroxyacetone kinase. | FMN cyclase. While FAD was the best substrate tested the enzyme also splits ribonucleoside diphosphate-X compounds in which X is an acyclic or cyclic monosaccharide or derivative bearing an X-OH group that is able to attack internally the proximal phosphorus with the geometry necessary to form a P=X product; either a five-atom monocyclic phosphodiester or a cis-bicyclic phosphodiester-pyranose fusion.-!-The reaction is strongly inhibited by ADP or ATP but is unaffected by the presence of the product, cFMN. dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. | ATP + D-glyceraldehyde = ADP + D-glyceraldehyde 3-phosphate + H(+). | ATP + dihydroxyacetone = ADP + dihydroxyacetone phosphate + H(+). | FAD = AMP + H(+) + riboflavin cyclic-4',5'-phosphate. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Glycerolipid metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|RIG-I-like receptor signaling pathway 1.0 K00863:DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]|K05878:dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 274090 0 0 0 0 0 0 0 0 0 0 0 0 128265 0 0 0 0 0 0 0 0 0 0 0 0 0 3033889 4427940 4460422 2332505 3858928 8064920 4611438 2050543 3980134 5527901 0 2518515 1731017 4639226 3844485 2711244 6328907 0 7974401 0 5653059 10897142 0 8374593 5241899 4066113 3012525 0 7099905 5965643 1692345 2298300 4353328 2962323 2619828 2783091 3010535 3735024 0 0 0 0 0 0 0 0 0 0 0 0 0 314453 0 0 0 0 0 0 0 0 0 0 0 288464 0 0 0 0 0 0 0 0 0 0 0 0 0 693593 0 0 0 0 0 0 0 462288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343698 295450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CQGGFC(Carbamidomethyl)GPR MGYG000001365_00857;MGYG000004667_02863;MGYG000002223_00242;MGYG000000395_00387;MGYG000002528_01430;MGYG000001300_01090;MGYG000000615_00659;MGYG000003899_00568;MGYG000001339_00546;MGYG000003291_01075;MGYG000000121_02636;MGYG000002274_01878;MGYG000004732_01408;MGYG000002934_02590;MGYG000001616_00737;MGYG000001464_01654;MGYG000000080_03188;MGYG000002641_01322;MGYG000000028_00488;MGYG000002651_01302 domain d__Bacteria 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,3WH8P@541000|Ruminococcaceae 0.4 186801|Clostridia 0.7 C 0.75 FAD dependent oxidoreductase 0.85 glpA 0.7 - 1.0 1.1.5.3 0.9 ko:K00111 0.85 ko00564,ko01110,map00564,map01110 0.9 - 1.0 R00848 0.9 RC00029 0.9 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD,NAD_binding_8 0.7 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001365_00857 0.05 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 0.9 0.9 0.9 0.9 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 0.9 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 0.85 none 1.0 742712 879645 1160444 851595 298418 938469 604684 0 739353 766796 527397 0 1068926 798741 606948 726981 728807 0 1715691 834983 267728 814983 0 601287 852387 818288 568140 0 563092 411242 600835 537835 932338 1266545 0 548930 488261 991046 1624134 2126484 1330292 1351868 970512 1771692 1869822 0 1672128 393362 655025 0 1010775 1644735 1169447 800757 1362975 0 2489629 1718039 222284 1075545 0 1844816 1794197 1374025 1664464 0 443471 1182620 1904086 1488560 1195976 1331192 0 1217755 1177343 1450410 676229 3500295 955455 0 367496 1103519 852974 0 779874 397878 931887 0 989648 624502 858456 1106162 961544 0 1072257 787040 1104023 3333965 0 787844 754074 610279 834297 0 1858347 454633 660434 2566855 1342773 1494845 0 370822 516205 908868 727124 1002450 1329905 714477 1174074 1168186 1534838 0 1245956 881075 875254 0 1410528 1076701 956748 878663 1010788 0 1356512 1174933 297285 933600 0 1038056 1320746 892588 959591 0 1969822 1231279 1331159 1307471 1564572 1167567 0 704451 978422 1373649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 836289 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CQKEEIFEK MGYG000002517_01956 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 Belongs to the UPF0237 family 1.0 - 1.0 - 1.0 - 1.0 ko:K07166 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ACT_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01956 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07166:K07166; ACT domain-containing protein 1.0 none 1.0 0 0 0 0 0 0 0 439614 0 0 0 0 0 0 308068 0 0 0 0 0 0 0 0 0 0 0 476566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391882 0 0 0 0 0 0 0 0 0 0 0 0 2277674 0 0 0 0 0 0 3434613 2259079 0 0 0 0 0 3347437 0 0 0 0 0 0 0 0 0 3499451 2835671 2258262 0 0 0 0 0 0 0 0 0 3076655 0 1740472 0 0 0 0 0 0 1277149 1711145 0 0 0 0 0 2219467 0 0 0 0 0 0 0 0 0 1595948 1433781 1396338 0 0 0 0 0 0 0 0 0 2292674 0 +(Pyro-carbamidomethyl)CQPGSITC(Carbamidomethyl)HTK MGYG000002528_01098 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01098 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 427271 0 0 0 285944 0 0 0 0 0 0 0 0 0 193739 0 0 0 0 0 384649 0 0 259981 0 0 0 186289 0 0 290372 0 0 0 0 0 0 0 585843 0 0 0 358699 0 0 0 0 0 0 0 0 0 267789 0 0 0 0 0 0 0 0 763137 0 0 0 0 0 425492 245641 0 0 0 0 0 0 0 1681940 0 0 0 1594302 0 1040324 0 0 0 0 0 0 0 909879 0 0 1183684 0 1055166 2751964 0 1246643 1581598 0 0 0 3226126 0 700118 1411797 0 1161249 0 789800 0 0 0 1964482 0 0 0 796115 0 314066 0 0 0 0 0 0 0 761278 0 0 202907 0 338051 887061 0 783598 448427 0 0 0 4624590 0 1334837 1690131 0 0 0 348599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CQSPANLLK MGYG000002641_02188 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp003449675|m__MGYG000002641 1.0 COG1653@1|root,COG1653@2|Bacteria,1TS6D@1239|Firmicutes,248CI@186801|Clostridia,27JZY@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K17318 1.0 ko02010,map02010 1.0 M00603 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.29,3.A.1.1.9 1.0 - 1.0 - 1.0 SBP_bac_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002641_02188 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K17318:lplA; putative aldouronate transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308609 0 0 0 0 343770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 799965 0 0 0 0 820508 0 0 0 0 802588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340090 0 0 0 0 294168 0 0 0 0 261039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 412762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 123634 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CQSTNDAYPTGFR MGYG000002535_03845;MGYG000002507_03184;MGYG000002494_02672;MGYG000002323_03828;MGYG000002506_03862;MGYG000002515_04056 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,1RP5Z@1236|Gammaproteobacteria,3XP1Y@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Aspartate ammonia-lyase 1.0 aspA 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319 1.0 4.3.1.1 1.0 ko:K01744 1.0 ko00250,ko01100,map00250,map01100 1.0 - 1.0 R00490 1.0 RC00316,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_2250,iECs_1301.ECs5120,iG2583_1286.G2583_4966,iSBO_1134.SBO_4317,iSDY_1059.SDY_4444,iSF_1195.SF4293,iSFxv_1172.SFxv_4682,iSSON_1240.SSON_4322,iS_1188.S4560,iUTI89_1310.UTI89_C4736,iYL1228.KPN_04529,iZ_1308.Z5744,ic_1306.c5222 1.0 FumaraseC_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002535_03845 0.16666666666666666 aspartate ammonia-lyase. fumaric aminase. - L-aspartate = fumarate + NH4(+). 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01744:aspA; aspartate ammonia-lyase [EC:4.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 570889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 510921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 668784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 773931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CQVVEGGGEILPSEK MGYG000004797_01913;MGYG000002478_03723;MGYG000000243_00371 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2871@1|root,COG2871@2|Bacteria,4NFKC@976|Bacteroidetes,2FN44@200643|Bacteroidia,4AKAD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway 1.0 nqrF 1.0 - 1.0 1.6.5.8 1.0 ko:K00351 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_6,Fer2,NAD_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01913 0.3333333333333333 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 - 1.0 K00351:nqrF; Na+-transporting NADH:ubiquinone oxidoreductase subunit F [EC:7.2.1.1] 1.0 none 1.0 0 0 0 0 830935 0 0 0 0 0 0 0 0 0 0 830886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 923790 0 0 0 0 0 0 0 0 0 0 746525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644497 0 0 0 0 0 0 0 0 0 0 1005787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243114 0 0 0 0 0 0 0 0 0 0 506195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488013 0 0 0 0 0 0 0 0 0 0 977359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CRDLTDDEVK MGYG000003702_00674;MGYG000001315_01362;MGYG000004271_00041;MGYG000000271_01086;MGYG000000312_01473 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia 0.8 186801|Clostridia 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 - 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003702_00674 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02952:RP-S13, rpsM; small subunit ribosomal protein S13 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CRDLTDDEVKK MGYG000001315_01362 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 - 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01362 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02952:RP-S13, rpsM; small subunit ribosomal protein S13 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321332 0 0 0 0 213686 0 0 456253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522889 0 0 0 0 547959 0 0 481603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87393 0 0 0 0 112191 0 0 396811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498096 0 0 0 0 485926 0 0 318861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437640 0 0 0 0 257657 +(Pyro-carbamidomethyl)CRDLTDDEVKR MGYG000004271_00041;MGYG000000271_01086 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 - 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00041 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02952:RP-S13, rpsM; small subunit ribosomal protein S13 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CRPDEVAYAHAHNVPVPEGANDNPYSIDDNLWGR MGYG000002775_00228;MGYG000003266_01591 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0137@1|root,COG0137@2|Bacteria,2GK96@201174|Actinobacteria,4CV0T@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Belongs to the argininosuccinate synthase family. Type 1 subfamily 1.0 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002775_00228 0.5 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids|Fluid shear stress and atherosclerosis 1.0 K01940:argG, ASS1; argininosuccinate synthase [EC:6.3.4.5] 1.0 none 1.0 0 883507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CSANTDKEGK MGYG000000412_00523;MGYG000000236_04489;MGYG000001319_00792;MGYG000003937_01472;MGYG000000084_02464;MGYG000001302.1_01989 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia 0.3333333333333333 186801|Clostridia 0.5 H 0.8333333333333334 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 - 0.6666666666666666 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000412_00523 0.16666666666666666 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 583195 0 0 0 0 334290 0 0 0 0 379400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 556487 0 0 0 0 287853 0 0 0 0 948503 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CSDQASMHIR MGYG000002517_00142 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0037@1|root,COG0037@2|Bacteria,1V1S0@1239|Firmicutes,24BSC@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 tRNA processing 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00142 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1191837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CSFEVAAYDQGAR MGYG000002494_02793;MGYG000002323_03719;MGYG000002534_04280;MGYG000002515_04199 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria,1RQ59@1236|Gammaproteobacteria 0.75 1236|Gammaproteobacteria 1.0 E 1.0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline 1.0 argI 1.0 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.1.3.3,2.1.3.9 1.0 ko:K00611,ko:K09065 1.0 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 1.0 M00029,M00844,M00845 1.0 R01398,R07245 1.0 RC00096 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECS88_1305.ECS88_4841 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02793 0.25 ornithine carbamoyltransferase. | N-acetylornithine carbamoyltransferase. OTCase. | N-acetylornithine transcarbamylase. The plant enzyme also catalyzes the reactions of EC 2.1.3.6, EC 2.7.2.2 and EC 3.5.3.12, thus acting as putrescine synthase, converting agmatine and ornithine into putrescine and citrulline respectively. | Differs from EC 2.1.3.3.-!-This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic pathway of several eubacteria and has no catalytic activity with L-ornithine as substrate. carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate. | carbamoyl phosphate + N(2)-acetyl-L-ornithine = H(+) + N(2)-acetyl-L- citrulline + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00611:OTC, argF, argI; ornithine carbamoyltransferase [EC:2.1.3.3]|K09065:argF; N-acetylornithine carbamoyltransferase [EC:2.1.3.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1054537 0 0 0 0 0 0 535066 0 0 0 0 0 0 0 0 1041424 0 841847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CSHEMDWVR MGYG000000196_05082;MGYG000000196_01061 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0673@1|root,COG0673@2|Bacteria,4NEN5@976|Bacteroidetes,2FP28@200643|Bacteroidia,4AP35@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tat pathway signal sequence domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C,TAT_signal 1.0 - 1.0 - 0.5 - 1.0 - 1.0 MGYG000000196_05082 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 1660301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1978287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1193702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CSIIEVM(Oxidation)GR MGYG000001714_01207;MGYG000004140_01431;MGYG000000263_02969;MGYG000000389_01497;MGYG000002445_01890;MGYG000002670_01194;MGYG000001748_00489;MGYG000000164_01314;MGYG000000193_01502;MGYG000002131_01267;MGYG000000262_01672;MGYG000004271_01479;MGYG000001338_03108;MGYG000000200_01715;MGYG000004785_01977;MGYG000000404_01769;MGYG000002298_02985;MGYG000000252_03136;MGYG000000489_01140;MGYG000000251_02553;MGYG000000087_01570;MGYG000001688_01941;MGYG000002945_02739;MGYG000004799_00788;MGYG000001619_00145;MGYG000004879_03089;MGYG000002517_00722;MGYG000000233_02644;MGYG000002145_01062;MGYG000001374_02297;MGYG000001637_01748;MGYG000004869_03739;MGYG000004519_00079;MGYG000000133_02661;MGYG000003074_00958;MGYG000000205_01904;MGYG000000271_01933;MGYG000002985_01092;MGYG000000118_00086;MGYG000000255_02050;MGYG000001315_03537;MGYG000000201_02247;MGYG000002312_00043;MGYG000000002_03264;MGYG000003486_02032;MGYG000000806_01094;MGYG000000378_01139;MGYG000003012_00904;MGYG000000187_00684;MGYG000002992_01459;MGYG000000152_00728;MGYG000000038_01820;MGYG000000142_02989;MGYG000002492_00955;MGYG000000216_01646;MGYG000000909_01001;MGYG000004589_01118;MGYG000001199_00400;MGYG000000202_02060;MGYG000003694_02580;MGYG000000301_01958;MGYG000000281_00124;MGYG000002279_02763;MGYG000002393_02419;MGYG000001319_01087 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3XYH6@572511|Blautia 0.3076923076923077 186801|Clostridia 1.0 F 0.5230769230769231 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001714_01207 0.015384615384615385 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CSIIEVMGR MGYG000001714_01207;MGYG000004140_01431;MGYG000000263_02969;MGYG000000389_01497;MGYG000002445_01890;MGYG000002670_01194;MGYG000001748_00489;MGYG000000164_01314;MGYG000000193_01502;MGYG000002131_01267;MGYG000000262_01672;MGYG000004271_01479;MGYG000001338_03108;MGYG000000200_01715;MGYG000004785_01977;MGYG000000404_01769;MGYG000002298_02985;MGYG000000252_03136;MGYG000000489_01140;MGYG000000251_02553;MGYG000000087_01570;MGYG000001688_01941;MGYG000002945_02739;MGYG000004799_00788;MGYG000001619_00145;MGYG000004879_03089;MGYG000002517_00722;MGYG000000233_02644;MGYG000002145_01062;MGYG000001374_02297;MGYG000001637_01748;MGYG000004869_03739;MGYG000004519_00079;MGYG000000133_02661;MGYG000003074_00958;MGYG000000205_01904;MGYG000000271_01933;MGYG000002985_01092;MGYG000000118_00086;MGYG000000255_02050;MGYG000001315_03537;MGYG000000201_02247;MGYG000002312_00043;MGYG000000002_03264;MGYG000003486_02032;MGYG000000806_01094;MGYG000000378_01139;MGYG000003012_00904;MGYG000000187_00684;MGYG000002992_01459;MGYG000000152_00728;MGYG000000038_01820;MGYG000000142_02989;MGYG000002492_00955;MGYG000000216_01646;MGYG000000909_01001;MGYG000004589_01118;MGYG000001199_00400;MGYG000000202_02060;MGYG000003694_02580;MGYG000000301_01958;MGYG000000281_00124;MGYG000002279_02763;MGYG000002393_02419;MGYG000001319_01087 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3XYH6@572511|Blautia 0.3076923076923077 186801|Clostridia 1.0 F 0.5230769230769231 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001714_01207 0.015384615384615385 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 537874 660030 638133 475946 848722 573139 436771 910032 569389 849915 777753 939178 628967 418933 709332 452707 539477 591585 638883 720729 693965 932136 841540 450320 860788 597535 730930 966680 735734 747848 484669 701477 503783 614896 702159 611652 549840 435790 349406 587004 322631 501556 565878 115800 573804 550381 255959 421969 440535 388110 484002 315215 386954 292118 181060 1361552 415270 454943 335521 292514 955512 501353 406630 418700 560457 1263211 656345 360555 616477 457827 317329 478425 482016 404982 300394 356589 745757 824792 725646 522755 364291 471465 504431 692699 484908 687718 541610 796822 677714 698912 765888 644468 692621 478409 740051 677281 682566 641119 637764 502276 841958 892519 711982 850164 588228 690536 593107 891040 1006764 863028 867651 435719 635542 779568 760749 605372 441127 920237 580928 367818 468807 883031 927279 672045 519193 603331 475456 1032773 964805 594726 633207 272525 656722 670613 635376 312361 126896 180525 620111 716696 796770 459518 571614 858878 671988 586902 482963 573108 1082165 769548 872034 542671 994357 1142858 1137673 549744 519494 832505 967474 766121 638469 1110763 945136 903522 495561 1219999 1024859 740523 935750 255933 734603 415324 816068 797345 350981 648953 990778 859857 871152 451069 624070 420825 813968 789056 1230469 525748 687221 815755 642435 590874 +(Pyro-carbamidomethyl)CSIVEVMGR MGYG000000650_00890;MGYG000000989_02475;MGYG000000028_00264;MGYG000002528_01287;MGYG000000179_04958;MGYG000000080_02619 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,2682U@186813|unclassified Clostridiales 0.8333333333333334 186801|Clostridia 1.0 G 0.8333333333333334 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000650_00890 0.16666666666666666 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106682 0 80174 0 0 0 0 142919 0 0 0 0 0 0 0 0 0 0 412254 0 0 0 135138 0 0 0 0 0 0 0 0 0 81157 57418 0 0 61112 0 105451 0 374880 0 0 0 0 0 0 0 83448 0 0 0 0 96284 0 373622 666266 0 0 0 413236 0 0 249099 284296 0 0 0 0 345644 319050 300459 0 0 265194 0 919383 0 447524 0 311275 0 0 667566 0 0 976972 0 420463 0 0 310801 0 137768 252119 0 0 0 87940 0 0 131225 131322 0 0 0 0 246208 177690 0 0 0 203167 0 95301 0 0 0 0 0 0 483707 0 0 205066 0 91855 0 0 0 0 353257 0 0 0 0 0 0 0 341998 326193 0 0 0 0 395678 121919 361314 0 0 286805 0 303851 0 0 0 362029 0 0 762178 0 0 0 0 295951 0 0 322830 0 +(Pyro-carbamidomethyl)CSNNYGPYHFPEK MGYG000001661_01673;MGYG000002994_00738;MGYG000003922_00043;MGYG000004558_01494;MGYG000001599_00610;MGYG000004748_00803;MGYG000000029_00536;MGYG000002549_04302;MGYG000000105_02489;MGYG000000255_02670;MGYG000000696_01314;MGYG000000146_01522;MGYG000002992_01118;MGYG000000236_00855;MGYG000002506_03458;MGYG000004762_00029;MGYG000000174_02161;MGYG000000077_01037;MGYG000003701_00934;MGYG000004839_00803;MGYG000000187_00408;MGYG000004317_01742;MGYG000000205_01470;MGYG000001750_00039;MGYG000002950.1_00427;MGYG000000193_02344;MGYG000000013_01636;MGYG000001310_02226;MGYG000001543_01411;MGYG000003681_00071;MGYG000002291_02998;MGYG000000142_02711;MGYG000004479_00899;MGYG000003312_01661;MGYG000000054_02319;MGYG000001378_04346;MGYG000002033_00278;MGYG000001400_02608;MGYG000004561_00703;MGYG000003695_00289;MGYG000000216_01929;MGYG000001783_01061;MGYG000002279_00355;MGYG000000200_01470;MGYG000004604_01556;MGYG000000249_00466;MGYG000002312_00890;MGYG000001313_03263;MGYG000001617_02017;MGYG000004797_03148;MGYG000002952_00715;MGYG000001306_03162;MGYG000002560_02224;MGYG000004185_00765;MGYG000003351_01794;MGYG000002528_00617;MGYG000000781_02576;MGYG000000179_01049;MGYG000003165_01329;MGYG000000044_03155;MGYG000000206_00137;MGYG000001141_01051;MGYG000000018_00879;MGYG000002156_00398;MGYG000003581_01363;MGYG000000251_00915;MGYG000002171_02673;MGYG000001623_02871;MGYG000002281_03831;MGYG000001345_03507;MGYG000002478_00328;MGYG000003367_00501;MGYG000001787_01258;MGYG000002098_00381;MGYG000000273_01234;MGYG000000243_02180;MGYG000000028_01398;MGYG000000356_02067;MGYG000001461_03061;MGYG000001364_01620;MGYG000000107_05121;MGYG000001697_00958;MGYG000000262_02262;MGYG000004899_01501;MGYG000003374_01808;MGYG000002756_03331;MGYG000000222_03512;MGYG000004876_01367;MGYG000000078_00616;MGYG000001338_01660;MGYG000001346_00923;MGYG000002788_01238;MGYG000000562_00802;MGYG000002717_00859;MGYG000004757_01843;MGYG000000038_02127;MGYG000000233_00880;MGYG000000184_00391 domain d__Bacteria 1.0 COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,2FMUH@200643|Bacteroidia,4AME0@815|Bacteroidaceae 0.3979591836734694 976|Bacteroidetes 0.4897959183673469 M 0.9897959183673469 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily 0.9285714285714286 rfbB 0.9795918367346939 - 0.9897959183673469 4.2.1.46 0.9693877551020408 ko:K01710 0.9693877551020408 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 0.9693877551020408 M00793 0.9693877551020408 R06513 0.9693877551020408 RC00402 0.9693877551020408 ko00000,ko00001,ko00002,ko01000 0.9693877551020408 - 1.0 - 1.0 - 0.9897959183673469 GDP_Man_Dehyd 0.9897959183673469 - 1.0 - 1.0 - 1.0 GT2 0.8571428571428571 MGYG000001661_01673 0.01020408163265306 dTDP-glucose 4,6-dehydratase. - - dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. 0.9693877551020408 0.9693877551020408 0.9693877551020408 0.9693877551020408 Streptomycin biosynthesis|Polyketide sugar unit biosynthesis|Acarbose and validamycin biosynthesis|Biosynthesis of vancomycin group antibiotics 0.9693877551020408 K01710:rfbB, rmlB, rffG; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] 0.9693877551020408 none 1.0 884512 744582 1019513 0 979627 988510 0 1437399 0 0 1079239 0 1101004 824159 1216425 1139948 0 866205 1176866 1079147 0 886786 703931 799935 0 1033022 892849 863280 0 0 0 921491 809805 830317 0 0 773209 744026 834637 935730 872531 0 1187491 635282 0 974375 0 0 1103049 0 1036105 763111 452216 751655 0 1468279 849234 856652 0 608142 822766 767548 0 940889 915840 1151880 0 0 0 1000104 884733 905987 0 0 612697 932502 1038556 2016644 1164577 0 764504 928692 0 1319982 0 0 804012 0 997367 1052664 1221585 1070919 0 707510 1244457 1271214 0 1564577 863645 856895 0 1189499 1240847 825479 0 0 0 959342 1333179 1351962 0 0 1318176 1084113 718131 902857 415847 0 1016244 491671 0 634016 0 0 737845 0 776940 723297 725090 783783 0 355299 605423 881426 0 421396 645651 381442 0 571953 677056 533687 0 0 0 779172 703367 414044 0 0 442113 374779 625067 555807 512658 0 616275 601465 0 800285 0 0 501144 0 689563 711615 331045 714229 0 761507 707259 536126 0 649373 840580 550614 0 815842 312106 826011 0 0 0 517940 851947 963798 0 0 840156 871857 +(Pyro-carbamidomethyl)CSPFRVPLAR MGYG000000236_00181;MGYG000002298_01806;MGYG000004482_00393;MGYG000002079_00687;MGYG000001415_02125;MGYG000002727_00240;MGYG000004760_00878;MGYG000002560_01450;MGYG000001688_03814;MGYG000001698_00702;MGYG000000378_00784;MGYG000004891_00190;MGYG000001313_01473;MGYG000002208_00666;MGYG000001374_00487;MGYG000001577_00663;MGYG000002517_01243;MGYG000000074_01177;MGYG000002963_02777;MGYG000002720_01364;MGYG000001714_01953;MGYG000002139_00077;MGYG000002933_01184;MGYG000001665_01593;MGYG000003801_01123;MGYG000000187_00493;MGYG000003236_01337;MGYG000000371_01679;MGYG000000262_01988;MGYG000003366_01811;MGYG000000044_00817;MGYG000001641_02069;MGYG000000233_02503;MGYG000004869_04101;MGYG000003468_00865;MGYG000000111_01891;MGYG000001789_01569;MGYG000004797_01193;MGYG000001871_00692;MGYG000002040_00906;MGYG000004296_00104;MGYG000002133_02142;MGYG000000312_02404;MGYG000000356_00934;MGYG000001496_03326;MGYG000001562_02560;MGYG000002293_00252;MGYG000003312_03561;MGYG000002105_00879;MGYG000004763_00142;MGYG000002965_00229;MGYG000004221_00458;MGYG000004667_00970;MGYG000001687_00537;MGYG000003374_01797;MGYG000003921_00033;MGYG000002670_01671;MGYG000002590_00564;MGYG000002057_00345;MGYG000000728_00587;MGYG000002274_02693;MGYG000001136_01739;MGYG000000359_00714;MGYG000001345_02795;MGYG000000212_00440;MGYG000002794_01254;MGYG000004733_01907;MGYG000002580_00394;MGYG000004642_01131;MGYG000000170_00404;MGYG000000076_02377;MGYG000000184_00575;MGYG000000281_03419;MGYG000002702_00763;MGYG000000223_02468;MGYG000003899_02226;MGYG000002102_01725;MGYG000001707_02428;MGYG000002922_00885;MGYG000000255_02207;MGYG000000345_00443;MGYG000002212_01829;MGYG000002194_01689;MGYG000002912_00804;MGYG000000198_00250;MGYG000002278_00689;MGYG000002945_01502;MGYG000000133_02955;MGYG000002279_01986;MGYG000000251_01169;MGYG000001748_00979;MGYG000003166_00833;MGYG000000377_01737;MGYG000000636_01370;MGYG000002966_02744;MGYG000000989_01009;MGYG000003952_01418;MGYG000001637_01169;MGYG000000087_02439;MGYG000004713_00347;MGYG000000013_03892;MGYG000001597_00394;MGYG000001615_00145;MGYG000002098_00511;MGYG000001780_04079;MGYG000002926_01683;MGYG000002247_01703;MGYG000003681_00659;MGYG000003542_01534;MGYG000000205_02701;MGYG000001315_01921;MGYG000001300_02837;MGYG000000003_01500;MGYG000000743_01457;MGYG000000352_00288;MGYG000004732_02304;MGYG000004475_00310;MGYG000001328_00836;MGYG000002549_01561;MGYG000003702_00366;MGYG000002552_02286;MGYG000001346_03147;MGYG000003697_00469;MGYG000000404_01435;MGYG000004784_01123;MGYG000002492_01692;MGYG000003486_02360;MGYG000004743_00400;MGYG000002218_01508;MGYG000000489_00801;MGYG000003446_00860;MGYG000000915_00888;MGYG000000142_02834;MGYG000003891_00830;MGYG000000222_00273;MGYG000000171_00241;MGYG000004487_00114;MGYG000000280_02154;MGYG000003819_01577;MGYG000000325_02351;MGYG000000245_03386;MGYG000004087_01282;MGYG000000258_01879;MGYG000000036_01410;MGYG000000179_00100;MGYG000003074_00103;MGYG000003311_01206;MGYG000001787_02320;MGYG000000098_03346;MGYG000002934_01311;MGYG000001647_00185;MGYG000001738_01167;MGYG000003279_00708;MGYG000000196_02017;MGYG000000022_02788;MGYG000003450_00463;MGYG000004810_00381;MGYG000001754_01214;MGYG000001338_02151;MGYG000001646_00500;MGYG000001666_00300;MGYG000003202_01304;MGYG000001310_01399;MGYG000003694_01656;MGYG000001378_01176;MGYG000000077_02459;MGYG000002528_02478;MGYG000000701_00789;MGYG000002523_01400;MGYG000000140_01464;MGYG000002143_00035;MGYG000000392_01615;MGYG000000243_00277;MGYG000004271_01396;MGYG000001786_00858;MGYG000002393_00923;MGYG000002905_00879;MGYG000004517_00262;MGYG000000383_01314;MGYG000001733_00637;MGYG000004526_01655;MGYG000000193_00368;MGYG000003363_02147;MGYG000004879_02866;MGYG000000271_00388;MGYG000002159_01291;MGYG000000417_00539;MGYG000000031_02405;MGYG000000215_00031;MGYG000002478_03849;MGYG000000249_01089;MGYG000002753_00264;MGYG000003307_01519;MGYG000003469_00516;MGYG000002953_01784;MGYG000002438_03578;MGYG000004658_00597;MGYG000002007_01910;MGYG000001661_00974;MGYG000000673_01172;MGYG000000164_00358;MGYG000003381_00006;MGYG000001255_00900;MGYG000001651_00429;MGYG000002126_00460 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.24390243902439024 186801|Clostridia 0.7170731707317073 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8536585365853658 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9853658536585366 - 1.0 - 1.0 - 1.0 GT1 0.9902439024390244 MGYG000000236_00181 0.004878048780487805 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 3772286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4502144 0 0 0 0 0 0 0 0 0 0 3311115 0 977118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025307 0 0 0 0 0 0 0 0 0 0 792025 0 5070249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5851816 0 0 0 0 0 0 0 0 0 0 5181028 0 1762998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2389396 0 0 0 0 0 0 0 0 0 0 2689452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CSYGWAKED MGYG000002059_01430;MGYG000001564_01809;MGYG000000077_01442;MGYG000001493_05223;MGYG000000179_02171;MGYG000000262_02304;MGYG000000084_01195 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 0.42857142857142855 186801|Clostridia 1.0 F 0.7142857142857143 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002059_01430 0.14285714285714285 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 385854 0 104479 274866 0 0 0 0 0 0 0 0 0 0 797108 0 0 0 0 0 0 0 0 0 0 423610 0 0 371095 0 0 0 0 0 0 414984 392628 0 279538 0 0 0 0 0 0 0 0 0 0 0 0 0 143478 0 0 0 0 0 0 0 0 0 0 200076 0 0 345270 0 0 0 0 0 0 268296 262851 0 1045876 0 237504 563391 0 0 0 0 0 0 0 0 0 0 1029331 0 320706 0 0 0 0 0 0 0 0 945288 0 0 692617 0 0 0 235501 0 0 713355 567218 179836 656780 0 460895 553754 0 0 0 0 0 0 0 0 0 0 490210 0 867993 0 0 0 0 0 0 0 0 168991 0 0 770251 0 0 0 589498 0 0 516168 554199 671067 1594364 0 1111050 1378762 0 0 0 0 0 0 0 0 0 0 1731368 0 1175732 0 0 0 0 0 0 0 0 1631919 0 0 2092368 0 0 0 1180726 0 0 1553178 1368990 822947 +(Pyro-carbamidomethyl)CTDAVLAAIDEEKK MGYG000002834_00307;MGYG000002960_02297;MGYG000003697_02228;MGYG000002293_02268;MGYG000001056_01406 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0363@1|root,COG2120@1|root,COG0363@2|Bacteria,COG2120@2|Bacteria,4NDUN@976|Bacteroidetes,2FM2W@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 glucosamine-6-phosphate deaminase 1.0 nagB 1.0 - 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso,PIG-L,Sulfatase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002834_00307 0.2 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K02564:nagB, GNPDA; glucosamine-6-phosphate deaminase [EC:3.5.99.6] 1.0 none 1.0 0 0 0 0 0 136176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1492088 0 0 0 644187 2636578 0 0 0 0 1894472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CTEEHQAIVR MGYG000002535_00457;MGYG000002494_04238 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3171@1|root,COG3171@2|Bacteria,1RH3U@1224|Proteobacteria,1S6UT@1236|Gammaproteobacteria,3XPPI@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Protein with unknown function (DUF469) 1.0 yggL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 - 1.0 ko:K09923 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF469 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002535_00457 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K09923:K09923; uncharacterized protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1360817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1465879 0 1171449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CTEYGC(Carbamidomethyl)VNLK MGYG000001300_00298;MGYG000002274_00041 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,3WGGE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acetyl-CoA hydrolase/transferase C-terminal domain 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00298 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 936431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CTLTEEQIKTEAK MGYG000002517_01855 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 'glutamate synthase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4,Fer4_20,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01855 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 881973 0 0 0 0 0 0 0 0 0 0 0 0 1024252 992083 0 0 0 0 817932 0 0 0 0 892633 793612 0 0 0 0 0 0 0 0 0 0 923474 0 490413 0 0 0 0 0 0 0 0 0 0 0 0 679869 874889 0 0 0 0 386247 0 0 0 0 675488 661597 0 0 0 0 0 0 0 0 0 0 1004668 0 +(Pyro-carbamidomethyl)CTNFGMEKK MGYG000001056_01523;MGYG000004797_02703;MGYG000002549_02753;MGYG000001346_02848;MGYG000001378_02162;MGYG000002478_01618;MGYG000000182_00097;MGYG000003363_00431;MGYG000002293_00175;MGYG000002960_01099;MGYG000001313_02628;MGYG000000243_00156;MGYG000003697_00501;MGYG000002478_03534;MGYG000001345_00471;MGYG000002834_00254;MGYG000002171_02203;MGYG000004876_02773;MGYG000004797_03640 domain d__Bacteria 1.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FM4G@200643|Bacteroidia,4AMFG@815|Bacteroidaceae 0.5263157894736842 976|Bacteroidetes 0.9473684210526315 I 1.0 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 0.5263157894736842 mmdA 0.8421052631578947 - 1.0 - 0.8421052631578947 - 0.8421052631578947 - 0.8421052631578947 - 0.8421052631578947 - 0.8421052631578947 - 0.8421052631578947 - 0.8421052631578947 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 GH101 1.0 MGYG000001056_01523 0.05263157894736842 - - - - 0.8421052631578947 0.8421052631578947 0.8421052631578947 0.8421052631578947 - 0.8421052631578947 - 0.8421052631578947 none 1.0 1534540 1672873 2254647 1740013 2220418 1678112 0 1515480 0 0 1751611 1459839 1906695 2283933 0 2226980 1724567 967166 0 0 0 1372646 904781 2136831 0 1559306 1873233 905183 1941383 0 2193137 2152367 2270023 0 1894994 0 1867507 2711647 1975236 1102052 1745176 1506384 1635570 1426023 0 1693537 0 0 1728836 1620028 1672728 1667983 0 1684831 1582347 524932 0 0 0 1744498 898337 1087509 0 1819582 1920740 695845 1505008 0 935959 1416422 1601537 0 1968543 0 1820631 1461283 1568597 1442856 2272450 1735183 2101618 1778971 0 1691846 0 0 1741909 1487434 1708108 1647791 0 1463201 1148734 2150866 0 0 0 1246356 1675793 1798279 0 1399749 1669321 1898442 1649970 0 1826575 1528360 1436353 0 1679524 0 1869219 1788973 1072950 827611 1705419 1105033 1329717 1357951 0 1341522 0 0 1498299 1307096 1445650 1006805 0 1295038 974643 1191530 0 0 0 1265903 1426008 1238995 0 1333345 1341122 964273 1056543 0 1003292 1295486 1427182 0 1658428 0 1333495 1167015 1157679 824033 1064553 1383050 1980136 1801011 0 1451388 0 0 1513283 1503885 1718496 924068 0 1568451 1220697 1443476 0 0 0 1428568 1215630 1236042 0 1704040 1170987 1073958 1478812 0 1296337 1285286 755570 0 1909383 0 1676694 1550326 +(Pyro-carbamidomethyl)CTNFGQEKK MGYG000004769_00266;MGYG000000236_00438;MGYG000001337_03643 domain d__Bacteria 1.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FM4G@200643|Bacteroidia,4AMFG@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 0.6666666666666666 I 1.0 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 0.6666666666666666 mmdA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 GH101 1.0 MGYG000004769_00266 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1652402 0 0 0 0 1873997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1843897 0 1651385 0 1469976 0 0 0 0 0 0 0 0 0 0 1472747 0 1156451 0 0 0 0 1408663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1197790 0 1176266 0 865484 0 0 0 0 0 0 0 0 0 0 891136 0 1258385 0 0 0 0 1799821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1861975 0 1638475 0 1340856 0 0 0 0 0 0 0 0 0 0 956561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CTQELLFGK MGYG000002323_01542;MGYG000002506_00254;MGYG000002494_01389;MGYG000000093_01888 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,3XNR8@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 L-aspartate:2-oxoglutarate aminotransferase activity 1.0 aspC 1.0 GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.0 2.6.1.1,2.6.1.57 1.0 ko:K00813,ko:K00832 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 M00024,M00025,M00034,M00040 1.0 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 iPC815.YPO1410,iSFxv_1172.SFxv_1000 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_01542 0.25 aspartate transaminase. | aromatic-amino-acid transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. | L-methionine can also act as donor, more slowly.-!-Oxaloacetate can act as acceptor.-!-Controlled proteolysis converts the enzyme to EC 2.6.1.1. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. | 2-oxoglutarate + an aromatic L-alpha-amino acid = an aromatic oxo-acid + L-glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00813:aspC; aspartate aminotransferase [EC:2.6.1.1]|K00832:tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57] 1.0 none 1.0 0 165424 378253 0 0 0 0 0 0 0 0 0 0 0 0 0 136305 0 99261 0 0 0 0 0 0 0 0 0 0 0 0 0 200763 0 0 0 0 253970 0 254447 358762 0 0 0 0 0 0 0 0 0 0 0 0 0 493281 0 475983 0 0 0 0 0 0 0 0 0 0 0 0 0 309291 0 0 0 0 113051 0 86862 115241 0 0 0 0 0 0 0 0 0 0 0 0 0 83010 0 90807 0 0 0 0 0 0 0 0 0 0 0 0 0 66914 0 0 0 0 77681 0 73877 76229 0 0 0 0 0 0 0 0 0 0 0 0 0 138608 0 211346 0 0 0 0 0 0 0 0 0 0 0 0 0 169776 0 0 0 0 330656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CTSAHLGQAFTK MGYG000002438_00431;MGYG000000138_02261 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,2FNWR@200643|Bacteroidia,22XN3@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Xylose isomerase-like TIM barrel 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00431 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1164435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4283939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2484584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2739107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6904101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CTTNC(Carbamidomethyl)LAPIAK MGYG000004658_00366;MGYG000004757_00364;MGYG000000196_00479;MGYG000001562_00044;MGYG000000044_01948;MGYG000001643_00773;MGYG000001661_02632;MGYG000004464_00783;MGYG000004734_01400;MGYG000002478_03999;MGYG000001783_01519;MGYG000003697_01698;MGYG000001337_01464;MGYG000001789_00244;MGYG000002293_01263;MGYG000000243_01331;MGYG000004779_01244;MGYG000002506_01169;MGYG000003469_01436;MGYG000004756_01346;MGYG000000170_00182;MGYG000003202_00946;MGYG000001345_01069 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.43478260869565216 976|Bacteroidetes 0.8695652173913043 C 0.5217391304347826 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 0.9565217391304348 - 0.9565217391304348 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9565217391304348 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004658_00366 0.043478260869565216 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1627514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1906697 0 0 0 0 609219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CTTNC(Carbamidomethyl)LAPLAK MGYG000002999_00356;MGYG000004468_00660;MGYG000002540_02142;MGYG000000375_01483;MGYG000004734_01400;MGYG000001783_01519;MGYG000003697_01698;MGYG000002057_00658;MGYG000000074_00883;MGYG000004006_01717;MGYG000000354_00611;MGYG000002834_00628;MGYG000004756_01346;MGYG000002007_00386;MGYG000001692_02867;MGYG000002944_01470;MGYG000001345_01069;MGYG000002438_00285;MGYG000003110_00098;MGYG000001562_00044;MGYG000004464_00783;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000000111_00274;MGYG000004536_01441;MGYG000003372_00674;MGYG000000243_01331;MGYG000001448_01713;MGYG000004779_01244;MGYG000002506_01169;MGYG000000273_02725;MGYG000002275_01823;MGYG000003469_01436;MGYG000000099_02094;MGYG000001334_01647;MGYG000003643_00817;MGYG000004658_00366;MGYG000000044_01948;MGYG000001749_01249;MGYG000004487_00117;MGYG000004794_00985;MGYG000001546_00360;MGYG000003542_01626;MGYG000000423_01499;MGYG000001608_00559;MGYG000000412_01371;MGYG000001489_03093;MGYG000000377_02142;MGYG000004638_00838;MGYG000000445_00706;MGYG000001302.1_00095;MGYG000002556_00846;MGYG000003202_00946;MGYG000004411_00321;MGYG000002095_00148;MGYG000003681_00790;MGYG000000003_00712;MGYG000000097_00328;MGYG000002933_02039;MGYG000004482_00387;MGYG000000196_00479;MGYG000004757_00364;MGYG000001643_00773;MGYG000001661_02632;MGYG000003819_01468;MGYG000002549_00455;MGYG000000467_01930;MGYG000001337_01464;MGYG000002737_00455;MGYG000001789_00244;MGYG000002293_01263;MGYG000003155_00741;MGYG000000053_01377;MGYG000000170_00182;MGYG000004831_00204;MGYG000000673_01725;MGYG000002905_02083 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.28205128205128205 976|Bacteroidetes 0.6410256410256411 G 0.6153846153846154 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8717948717948718 gap 0.9743589743589743 - 0.9102564102564102 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9743589743589743 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002999_00356 0.01282051282051282 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 1090321 0 2254211 0 0 0 0 0 0 1289554 0 1591293 0 0 0 0 0 1245801 0 0 0 0 1215054 0 1468061 1586574 0 0 1402342 0 0 1712898 2184081 0 0 0 1515797 2119698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 149063 0 0 0 294273 0 0 0 0 0 0 152328 0 170654 0 0 0 0 0 694158 0 0 0 0 174527 0 246405 267503 0 545012 322798 0 0 259492 450381 0 0 0 415924 392588 1701300 0 2571998 0 0 0 0 0 0 1548231 0 2260557 0 0 0 0 0 2612788 0 0 0 0 1247982 0 2206999 2128330 0 1639746 1733360 0 0 2777060 2480211 0 0 0 1906531 1066028 0 0 170159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467634 0 0 0 0 468152 0 0 0 0 755584 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CTVEDYDYTKGQGFK MGYG000003697_01174 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0436@1|root,COG0436@2|Bacteria,4NFV4@976|Bacteroidetes,2FN4K@200643|Bacteroidia,4AMHU@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01174 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1553556 0 0 0 0 2731429 0 0 0 0 1486140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CTVNDFEYTAGK MGYG000002438_00501 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,2324H@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00501 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422854 0 0 0 0 239269 0 0 0 0 388828 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CTYFAVIDK MGYG000004797_02947;MGYG000001337_01561;MGYG000000243_00135;MGYG000002171_02490;MGYG000002478_02940;MGYG000000196_00570;MGYG000001378_02415 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_02947 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 118868 0 0 0 0 121420 0 0 0 0 188081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139321 0 0 0 0 121433 0 0 0 0 130312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157597 0 0 0 0 132494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232932 0 0 0 0 140685 0 0 0 0 146991 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVATHALNIFGDHSDVYAC(Carbamidomethyl)R MGYG000001637_01998;MGYG000003656_01278;MGYG000000233_01543;MGYG000000255_00343;MGYG000000404_01294;MGYG000000489_00545 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001637_01998 0.16666666666666666 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 519955 1701609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 984194 1339651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215969 382134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264522 182470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVC(Carbamidomethyl)TPDKK MGYG000000271_00468 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00468 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVDGITANAEHTK MGYG000002447_01881;MGYG000002447_01092 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Mesosutterella|s__Mesosutterella multiformis|m__MGYG000002447 1.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2W02M@28216|Betaproteobacteria,4PQCS@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 E 1.0 Fumarase C C-terminus 1.0 aspA 1.0 - 1.0 4.3.1.1 1.0 ko:K01744 1.0 ko00250,ko01100,map00250,map01100 1.0 - 1.0 R00490 1.0 RC00316,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FumaraseC_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002447_01881 0.5 aspartate ammonia-lyase. fumaric aminase. - L-aspartate = fumarate + NH4(+). 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01744:aspA; aspartate ammonia-lyase [EC:4.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1260676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVDMNDR MGYG000000031_02020;MGYG000003869_00786;MGYG000000118_02883;MGYG000000184_03010;MGYG000000212_02552;MGYG000000249_01748;MGYG000000133_00802;MGYG000000142_02498;MGYG000002036_00603;MGYG000001698_00102;MGYG000001356_01588;MGYG000001338_00681;MGYG000003355_04197;MGYG000000171_00584;MGYG000004762_01392;MGYG000002229_00638;MGYG000003628_00321;MGYG000001652_00547;MGYG000000268_00090;MGYG000002854_00387;MGYG000004628_02036;MGYG000002953_02673;MGYG000000142_00761;MGYG000001496_02657;MGYG000001683_01572;MGYG000001698_02021;MGYG000000212_01928;MGYG000004565_00983;MGYG000003468_00280;MGYG000002563_01362;MGYG000002836_01567;MGYG000004781_01910;MGYG000000140_00392;MGYG000004733_02867;MGYG000000466_00763;MGYG000003582_01115;MGYG000004285_01532;MGYG000000031_00146;MGYG000000739_00465;MGYG000003558_01066;MGYG000001777_01705;MGYG000004736_00479;MGYG000000301_00718;MGYG000001606_01069;MGYG000000002_02249;MGYG000001954_00253;MGYG000001493_00835;MGYG000004697_00027;MGYG000003589_00277;MGYG000000743_01174;MGYG000002835_00653;MGYG000000002_01091;MGYG000002279_01909;MGYG000001689_00148;MGYG000000146_00652;MGYG000000171_02356;MGYG000004735_00336;MGYG000004799_00369;MGYG000000119_00545;MGYG000000164_00746;MGYG000002057_01219;MGYG000001647_00733;MGYG000000099_00457;MGYG000002042_01022;MGYG000001651_01713;MGYG000002992_01647;MGYG000000127_02971;MGYG000002998_01059;MGYG000000251_02727;MGYG000001460_03056 domain d__Bacteria 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae 0.38571428571428573 186801|Clostridia 0.9857142857142858 H 0.7285714285714285 Belongs to the formate--tetrahydrofolate ligase family 0.6428571428571429 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_02020 0.014285714285714285 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01938:fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] 1.0 none 1.0 0 366298 379158 0 0 383629 0 345193 0 304795 804172 308425 0 0 866241 336263 278682 0 278102 0 591803 935168 0 185326 0 369607 314170 0 0 0 0 361971 321849 0 0 0 228463 591726 272519 577638 0 227800 0 93090 300056 130475 0 205794 518731 161569 0 0 253103 97603 135300 0 285542 0 117713 0 0 0 0 131307 365953 0 0 0 553014 0 154129 0 0 0 132285 258601 593612 657923 417160 443215 0 193975 375152 837506 0 780934 506883 607106 0 0 708237 746320 787969 0 656099 0 564526 1058192 0 666426 0 771621 690698 0 0 0 505899 960937 1001557 0 0 0 431807 545911 194165 811234 484928 0 0 0 157988 0 0 212428 344708 472416 0 0 169494 264208 322498 0 0 0 0 163854 0 0 0 0 0 0 0 0 630259 588394 677964 0 0 0 0 557122 1320242 1970046 2171063 1976880 0 1353789 1586039 1163253 0 1467362 569207 1466423 0 0 1321519 1020341 1118626 0 1083298 0 1202094 963782 0 432021 0 526538 990130 0 0 0 1392835 1664312 2061606 0 0 0 315399 1145186 +(Pyro-carbamidomethyl)CVDVAIVEAC(Carbamidomethyl)K MGYG000004769_01827 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,4H31P@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 succinate CoA transferase 1.0 scpC 1.0 - 1.0 2.8.3.18 1.0 ko:K18118 1.0 ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011 1.0 R10343 1.0 RC00012,RC00014 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01827 1.0 succinyl-CoA:acetate CoA-transferase. SCACT. In some bacteria the enzyme catalyzes the conversion of acetate to acetyl-CoA as part of a modified tricarboxylic acid (TCA) cycle.-!-In other organisms it converts acetyl-CoA to acetate during fermentation.-!-In some organisms the enzyme also catalyzes the activity of EC 2.8.3.27. acetate + succinyl-CoA = acetyl-CoA + succinate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K18118:aarC, cat1; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660713 652881 0 780241 499560 0 694371 0 0 837661 0 0 0 0 0 0 0 0 0 0 480232 0 478594 0 0 0 0 645431 0 0 0 550450 0 0 0 0 511891 0 521582 412833 0 176038 441674 0 319023 0 0 495950 0 0 0 0 0 0 0 0 0 0 372182 0 257874 0 0 0 0 378956 0 0 0 307568 0 0 0 0 198038 0 148780 0 0 0 0 0 0 0 0 189191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300531 0 0 0 0 209729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVENAYFIK MGYG000004893_02071;MGYG000003372_04160;MGYG000002689_01090;MGYG000002513_00431;MGYG000002535_03654;MGYG000000179_02516;MGYG000002574_02872;MGYG000001464_02324;MGYG000000242_02080;MGYG000004828_01853;MGYG000002494_02836;MGYG000000152_02649 domain d__Bacteria 1.0 COG3033@1|root,COG3033@2|Bacteria,1NG5U@1224|Proteobacteria,1RS6E@1236|Gammaproteobacteria,3WWJR@544|Citrobacter 0.3333333333333333 186801|Clostridia 0.5833333333333334 E 0.75 Beta-eliminating lyase 0.75 tpl 0.75 - 1.0 4.1.99.2 0.75 ko:K01668 0.75 ko00350,map00350 0.75 - 1.0 R00728 0.75 RC00355,RC00364 0.75 ko00000,ko00001,ko01000 0.75 - 1.0 - 1.0 - 1.0 Beta_elim_lyase 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004893_02071 0.08333333333333333 tyrosine phenol-lyase. beta-tyrosinase. The enzyme cleaves a carbon-carbon bond, releasing phenol and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-The enzyme also slowly catalyzes similar reactions with D-tyrosine, S-methyl-L-cysteine, L-cysteine, L-serine and D-serine. H2O + L-tyrosine = NH4(+) + phenol + pyruvate. 0.75 0.75 0.75 0.75 Tyrosine metabolism 0.75 K01668:E4.1.99.2; tyrosine phenol-lyase [EC:4.1.99.2] 0.75 none 1.0 0 0 116499 0 0 167630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239741 0 110639 0 0 0 0 0 0 0 0 225622 0 0 0 0 150979 0 0 315522 0 0 529982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492171 0 552141 0 0 0 0 0 0 0 0 406564 0 0 0 0 488797 0 0 323603 0 0 342029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453847 0 428218 0 0 0 0 0 0 0 0 514418 0 0 0 0 334317 0 0 310862 0 0 193910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117490 0 101087 0 0 0 0 0 0 0 0 118883 0 0 0 0 195336 0 0 79738 0 0 430849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 482422 0 475719 0 0 0 0 0 0 0 0 722513 0 0 0 0 627607 +(Pyro-carbamidomethyl)CVFTFKR MGYG000000243_01003 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0217@1|root,COG0217@2|Bacteria,4NE8Y@976|Bacteroidetes,2FN07@200643|Bacteroidia,4AK76@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 Transcriptional regulatory protein 1.0 yebC 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Transcrip_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01003 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 374887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 414787 0 0 0 0 381428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95427 +(Pyro-carbamidomethyl)CVGAALR MGYG000002506_02717 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3XNX9@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 K 1.0 transcriptional regulator 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02717 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 280644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435602 0 365357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 195051 0 97632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVGFELR MGYG000002494_04127 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3WV6W@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 K 1.0 Transcriptional regulator PadR-like family 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04127 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613176 0 0 0 524810 0 0 0 0 0 0 0 0 0 0 0 614217 0 101336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVHAMNK MGYG000002528_01429 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DAO,FAD_binding_2,FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01429 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1069953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVHAMNKK MGYG000002528_01429;MGYG000000028_00487 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DAO,FAD_binding_2,FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01429 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 125644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2959451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1831692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVIVEVNENMPR MGYG000002528_02671 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Acetyl-CoA hydrolase transferase 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02671 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 411985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 790339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1406887 0 0 0 0 0 0 1153026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVLQDGLHIR MGYG000000262_00350;MGYG000000077_01494 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,25UXF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Aldehyde dehydrogenase (NAD) family protein 1.0 pduP 1.0 - 1.0 1.2.1.87 1.0 ko:K13922 1.0 ko00640,map00640 1.0 - 1.0 R09097 1.0 RC00004,RC00184 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_00350 0.5 propanal dehydrogenase (CoA-propanoylating). - The enzyme forms a bifunctional complex with EC 4.1.3.43, with a tight channel connecting the two subunits.-!-Also acts, more slowly, on glycolaldehyde and butanal.-!-In Pseudomonas species the enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.10.-!-NADP(+) can replace NAD(+) with a much slower rate. CoA + NAD(+) + propanal = H(+) + NADH + propanoyl-CoA. 1.0 1.0 1.0 1.0 Propanoate metabolism 1.0 K13922:pduP; propionaldehyde dehydrogenase [EC:1.2.1.87] 1.0 none 1.0 791737 1347975 0 329929 0 898508 201543 959163 0 0 0 1119567 1573580 574954 943804 1421536 1001471 0 685913 995476 0 1460552 0 246179 1117637 659016 546844 0 733139 827967 596202 1240556 0 600425 549001 510233 386331 0 1640611 1547271 0 1313393 0 1336109 3584102 1155259 0 0 0 677500 902696 758126 1210023 607698 750998 0 1408727 2429809 0 897546 0 2498407 1391862 1365723 1400571 0 2907310 1261663 1531833 718059 0 1795163 1425047 1841114 1292373 0 3068797 5218710 0 4373107 0 3164294 950070 3273679 0 0 0 2377366 3036601 2070655 4148610 2917737 2453224 0 3674501 3714749 0 5087224 0 2003452 3513365 3071803 4257990 0 1026000 2458965 1518519 4112380 0 3799401 4606768 1133906 2941784 0 1278796 1808557 0 1545936 0 2546355 2013065 1395100 0 0 0 1083749 1907366 1399890 1176293 2942626 1846711 0 987783 1834063 0 2518746 0 2541061 1208025 711073 0 0 1790336 1480332 1557947 1365563 0 1134363 1221049 1005862 836043 0 2396953 3637712 0 2679215 0 2316627 1946567 2224337 0 0 0 2099673 3243831 2252723 2940998 3812985 2670412 0 3430360 2973016 0 2750747 0 2156883 2919795 2493038 2854633 0 1154756 3217757 4640122 3833477 0 3647273 2423992 2194973 3574642 0 +(Pyro-carbamidomethyl)CVMSDSLC(Carbamidomethyl)IR MGYG000000133_00166;MGYG000003355_02940;MGYG000000301_01358 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,3XZI5@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Aldehyde dehydrogenase family 1.0 eutE 1.0 - 1.0 1.2.1.10,1.2.1.87 1.0 ko:K00132,ko:K13922 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00228,R01172,R09097 1.0 RC00004,RC00184,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00166 0.3333333333333333 acetaldehyde dehydrogenase (acetylating). | propanal dehydrogenase (CoA-propanoylating). aldehyde dehydrogenase (acylating). Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme forms a bifunctional complex with EC 4.1.3.43, with a tight channel connecting the two subunits.-!-Also acts, more slowly, on glycolaldehyde and butanal.-!-In Pseudomonas species the enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.10.-!-NADP(+) can replace NAD(+) with a much slower rate. acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NAD(+) + propanal = H(+) + NADH + propanoyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00132:E1.2.1.10; acetaldehyde dehydrogenase (acetylating) [EC:1.2.1.10]|K13922:pduP; propionaldehyde dehydrogenase [EC:1.2.1.87] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVNDAATMIK MGYG000002670_01511;MGYG000000489_01023;MGYG000002492_00657 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002670_01511 0.3333333333333333 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 194795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135293 239390 766308 180321 1125200 259699 0 144744 301826 379709 689680 191386 647055 302834 265281 426417 214122 4151618 104168 489365 0 0 2080288 285862 317020 490067 473084 3247430 125324 190852 400329 0 792473 432370 270636 456286 242812 905172 803323 511412 3613286 861760 988433 589734 0 950750 712886 1012893 1738268 1314548 1578472 981254 1008110 1920500 866672 767748 684034 725436 0 746534 1255671 725607 1040923 1036040 1039791 1694557 780854 766986 1176340 0 4032728 871540 1076722 537624 862502 3925522 0 0 0 0 0 0 0 0 0 0 0 325012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268433 93827 0 0 122568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105094 0 149693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVQMLHDR MGYG000000084_01999 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger formicilis|m__MGYG000000084 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000000084_01999 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435760 0 0 0 0 454563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 753745 0 0 0 0 772933 0 0 0 0 943165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 512219 0 0 0 0 334424 0 0 0 0 696934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242678 0 0 0 0 467830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133863 0 0 0 0 1239555 0 0 0 0 1462098 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVSHDDDATK MGYG000000262_00532 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,25XEF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10439,ko:K17202 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212,M00590 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.11,3.A.1.2.13,3.A.1.2.16,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_00532 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein|K17202:eryG; erythritol transport system substrate-binding protein 1.0 none 1.0 0 222324 0 0 0 0 0 0 0 0 0 0 0 0 0 309001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 972338 0 0 0 0 0 0 0 0 0 0 0 0 0 742327 0 0 0 0 0 0 0 0 0 0 813339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170240 0 0 0 0 0 0 0 0 0 0 0 0 0 346539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CVVNAAGVYADVFHNMVSSK MGYG000002517_00257 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00257 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77892645 0 0 0 +(Pyro-carbamidomethyl)CWAAVKDLATK MGYG000000196_01785 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,4AMYK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_01785 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CWNDEFQSR MGYG000001300_02598;MGYG000002641_02082;MGYG000002934_02602;MGYG000001627_01176;MGYG000002272_02331;MGYG000003166_00861;MGYG000002545_01196;MGYG000003891_02475;MGYG000002274_01203 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae 0.8888888888888888 186801|Clostridia 0.8888888888888888 G 1.0 ABC-type sugar transport system periplasmic component 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02598 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 462455 0 0 0 0 151190 0 0 0 0 212043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1484379 0 0 0 0 1729671 0 0 0 0 1983169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CYAIEEVADQK MGYG000000053_01519;MGYG000000074_02434;MGYG000002007_00972;MGYG000000003_01115;MGYG000001562_02119;MGYG000004006_00750;MGYG000002082_01949 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,22VAD@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 1.0 mce 1.0 - 1.0 5.1.99.1 1.0 ko:K05606 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R02765,R09979 1.0 RC00780,RC02739 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glyoxalase_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000053_01519 0.14285714285714285 methylmalonyl-CoA epimerase. methylmalonyl coenzyme A racemase. - (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K05606:MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] 1.0 none 1.0 0 0 0 0 0 133323 0 0 0 252280 0 186527 0 0 336404 0 0 0 0 0 0 0 0 298542 0 262153 0 0 0 0 0 0 0 0 0 0 0 0 216364 0 0 399188 0 223761 0 0 0 259919 0 181084 0 0 338212 0 0 0 0 371434 0 0 0 0 0 296504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298559 0 0 0 0 0 0 0 0 0 0 198576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277697 0 840750 0 0 1071732 1289844 1251382 0 0 0 1013337 0 955987 0 0 773453 0 0 0 0 1795436 0 977028 0 987123 0 1130651 0 0 0 0 0 0 0 0 0 0 1052139 0 +(Pyro-carbamidomethyl)CYAIEEVADQKVR MGYG000000074_02434;MGYG000002082_01949 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,22VAD@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 1.0 mce 1.0 - 1.0 5.1.99.1 1.0 ko:K05606 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R02765,R09979 1.0 RC00780,RC02739 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glyoxalase_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02434 0.5 methylmalonyl-CoA epimerase. methylmalonyl coenzyme A racemase. - (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K05606:MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] 1.0 none 1.0 0 0 437846 0 0 573652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416237 0 0 0 505001 0 0 0 648297 0 0 647413 0 0 0 377591 0 0 0 396451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1330409 0 0 0 0 0 0 0 0 0 0 459635 0 0 0 346183 0 333263 0 698109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481023 0 0 0 0 0 0 500533 0 0 0 0 0 0 0 1075555 0 0 1729327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1483178 0 0 0 0 0 0 2175874 1318872 +(Pyro-carbamidomethyl)CYDAANAAAEEKVEAVR MGYG000000243_01121 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000243_01121 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2] 1.0 none 1.0 0 0 748581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518120 0 0 0 0 760133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381459 0 0 0 0 0 +(Pyro-carbamidomethyl)CYDAANAAAEEKVEAVRK MGYG000000243_01121 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1109@1|root,COG1109@2|Bacteria,4NFU7@976|Bacteroidetes,2FM0A@200643|Bacteroidia,4AMJH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II 1.0 pgcA 1.0 - 1.0 5.4.2.2 1.0 ko:K01835 1.0 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 1.0 M00549 1.0 R00959,R01057,R08639 1.0 RC00408 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000243_01121 1.0 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). phosphoglucose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K01835:pgm; phosphoglucomutase [EC:5.4.2.2] 1.0 none 1.0 1361531 0 2625314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1810170 0 0 0 0 0 0 2708484 0 0 0 972190 2958310 790372 0 588986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 905291 0 0 0 0 0 0 582584 0 0 0 1111246 799358 547350 0 779012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682806 0 0 0 485283 546410 603777 0 605351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489947 0 0 0 0 0 0 417347 0 0 0 599879 979728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CYDKELLER MGYG000000133_01552 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 COG NOG14451 non supervised orthologous group 1.0 - 1.0 - 1.0 2.7.4.25 1.0 ko:K00945 1.0 ko00240,ko01100,map00240,map01100 1.0 M00052 1.0 R00158,R00512,R01665 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01552 1.0 (d)CMP kinase. deoxycytidylate kinase. The prokaryotic cytidine monophosphate kinase specifically phosphorylates CMP (or dCMP), using ATP as the preferred phosphoryl donor.-!-Unlike EC 2.7.4.14, a eukaryotic enzyme that phosphorylates UMP and CMP with similar efficiency, the prokaryotic enzyme phosphorylates UMP with very low rates, and this function is catalyzed in prokaryotes by EC 2.7.4.22.-!-The enzyme phosphorylates dCMP nearly as well as it does CMP. (1) ATP + CMP = ADP + CDP. (2) ATP + dCMP = ADP + dCDP. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00945:cmk; CMP/dCMP kinase [EC:2.7.4.25] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125280 0 0 0 0 0 0 0 0 258606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 860281 0 800548 956096 0 348231 0 0 0 1476388 0 0 1205301 1248193 0 0 970023 0 0 0 1133703 700977 0 410829 0 688214 0 0 0 0 0 1420658 1765039 0 0 0 820775 591318 +(Pyro-carbamidomethyl)CYDSHKGPVVFR MGYG000002506_03438;MGYG000002323_00012;MGYG000003372_00850;MGYG000002534_04862;MGYG000002515_03619;MGYG000002477_00691;MGYG000002535_04244;MGYG000002494_01536;MGYG000002500_04676 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,3XMH2@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Acts on leucine, isoleucine and valine 1.0 ilvE 1.0 GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 iB21_1397.B21_03597,iECBD_1354.ECBD_4269,iECB_1328.ECB_03648,iECD_1391.ECD_03648,iECO103_1326.ECO103_4394 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_03438 0.1111111111111111 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Valine, leucine and isoleucine degradation|Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00826:E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42] 1.0 none 1.0 0 0 195666 0 173001 186812 0 0 0 0 0 0 0 0 0 0 237959 0 0 0 0 240300 0 172812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 760609 1080393 0 671018 741494 0 0 0 637604 0 0 0 0 0 0 1117405 0 0 0 0 784131 0 859967 882597 0 0 0 0 0 0 0 903603 0 0 0 0 846415 0 90603 128063 0 92670 120436 0 0 0 0 0 0 0 0 0 0 75628 0 0 0 0 95884 0 127426 597865 0 0 0 0 0 0 0 97146 0 0 0 0 0 0 336756 184584 0 0 0 0 0 0 162333 0 0 0 0 0 0 194251 0 0 0 0 123017 0 0 0 0 0 0 0 0 0 0 150695 0 0 0 0 179587 0 0 112892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CYGADDVQEGVAIMHHENVGVSITGNSTNPTR MGYG000000245_00061;MGYG000000404_00348;MGYG000002517_01686;MGYG000002492_01963;MGYG000004055_00746 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 0.8 183925|Methanobacteria 0.8 F 0.8 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 0.8 purD 0.8 - 1.0 6.3.4.13 0.8 ko:K01945 0.8 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 0.8 M00048 0.8 R04144 0.8 RC00090,RC00166 0.8 ko00000,ko00001,ko00002,ko01000 0.8 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000245_00061 0.2 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 0.8 0.8 0.8 0.8 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 0.8 K01945:purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] 0.8 none 1.0 0 0 362522 0 0 0 0 382934 0 0 0 0 0 0 0 0 0 0 0 0 384723 0 0 0 0 0 0 0 0 0 0 0 0 0 413433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204316 0 0 0 0 226879 0 0 610682 0 0 0 0 380196 0 0 0 0 0 0 0 0 0 0 0 0 306805 0 0 0 0 0 0 0 0 0 0 0 999404 0 515109 0 0 831236 0 0 468500 0 0 0 0 1012601 0 0 0 0 0 0 0 0 0 0 0 0 1104903 0 0 0 0 0 0 0 0 0 0 0 255317 0 1746150 0 0 348620 0 0 665084 0 0 0 0 537466 0 0 0 0 0 0 0 0 0 0 0 0 540232 0 0 0 0 0 0 0 0 0 0 0 1066167 0 8556140 0 0 653666 +(Pyro-carbamidomethyl)CYGADDVR MGYG000000013_02686;MGYG000003420_01320;MGYG000001658_01116;MGYG000003521_00824;MGYG000002802_02025;MGYG000000347_00819;MGYG000004824_01069;MGYG000002444_01680;MGYG000000269_00015;MGYG000003570_02445;MGYG000000781_01514;MGYG000001400_01185;MGYG000002582_01129;MGYG000004822_01055;MGYG000003891_01818;MGYG000004561_02010;MGYG000000042_01753;MGYG000000196_00899;MGYG000004763_01967;MGYG000004493_00376;MGYG000004797_02907;MGYG000000479_02090;MGYG000001925_01569;MGYG000001806_00888;MGYG000001346_01121;MGYG000002947_01620;MGYG000003535_01608;MGYG000001871_01775;MGYG000002293_01605;MGYG000004276_01664;MGYG000000043_00846;MGYG000000273_02192;MGYG000004482_01421;MGYG000003221_02162;MGYG000003470_00018;MGYG000003589_01350;MGYG000003922_03053;MGYG000003693_01584;MGYG000002603_00277;MGYG000001415_02505;MGYG000004699_02799;MGYG000002080_00203;MGYG000002275_01873;MGYG000003851_01315;MGYG000002218_00562;MGYG000000036_01924;MGYG000000258_00155;MGYG000001770_01218;MGYG000002834_01893;MGYG000001604_01691;MGYG000002438_03055;MGYG000001697_00682;MGYG000004464_00921;MGYG000001577_02122;MGYG000004729_00222;MGYG000000029_00187;MGYG000001378_03489;MGYG000004185_01308;MGYG000002213_00389;MGYG000000045_01847;MGYG000002281_03938;MGYG000001599_00424;MGYG000003457_01216;MGYG000003819_00577;MGYG000002098_00644;MGYG000000374_01026;MGYG000001237_02019;MGYG000000345_00815;MGYG000000433_01203;MGYG000003446_01092;MGYG000004019_01333;MGYG000000392_01121;MGYG000002478_02896;MGYG000001086_01322;MGYG000000223_01510;MGYG000001785_00655 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.32894736842105265 976|Bacteroidetes 0.5394736842105263 S 1.0 Psort location Cytoplasmic, score 8.96 0.47368421052631576 - 0.8947368421052632 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_02686 0.013157894736842105 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 367266 339799 0 0 0 0 0 0 0 0 0 303626 0 0 0 0 0 240162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396244 137746 0 0 0 0 0 0 0 0 0 243768 214493 0 0 0 0 270684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553590 144581 0 238120 0 0 0 0 0 0 0 482319 444020 0 0 0 0 188113 0 606564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273285 312464 0 138359 0 0 0 0 0 0 0 389970 308507 0 0 0 0 192302 0 279408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 892589 656535 0 754755 0 0 0 0 0 0 0 833491 589106 0 0 0 0 595916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Pyro-carbamidomethyl)CYGANDVMEGVAIMKK MGYG000001300_02120;MGYG000002274_00309;MGYG000000039_01269;MGYG000002224_01738 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02120 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 429911 1098275 472619 953803 814440 0 805017 0 0 1244673 1292296 1722328 613495 1034588 981089 0 2224685 331432 536322 1086848 0 1003958 919556 1182270 1088475 0 0 0 1342910 0 1583086 1892849 0 441138 1045293 1262935 1670319 0 1674426 2565761 900226 2097024 2686353 0 1478594 0 0 2039615 1299147 2110587 2932533 1135749 2513246 0 2477010 2014674 1089370 1371792 0 1588729 2837922 2111284 2007509 0 0 0 1807054 0 1038794 1570536 0 1527776 1522465 1290905 750621 0 567013 0 429001 628713 562109 0 331568 0 0 581944 334200 684256 381291 485491 0 0 943088 0 0 0 0 530006 701713 360097 673873 0 0 0 620119 0 325515 630657 0 436075 335305 468468 1335931 0 1582073 1131467 1321933 1679551 1833154 0 1544371 0 0 1348942 1917122 1627048 1520393 1486860 1523661 0 2623971 1238910 1720924 1442867 0 1315426 1837674 1565990 1461520 0 0 0 1825051 0 1704914 1928693 0 1189593 1526564 861013 0 0 593295 0 0 0 325831 0 0 0 0 0 0 0 0 293285 0 0 551236 0 0 0 0 0 0 0 0 0 0 0 0 0 425722 423122 0 0 511372 535019 +(Pyro-carbamidomethyl)CYNIETVEDQK MGYG000004185_00877;MGYG000001661_01872;MGYG000001346_02849;MGYG000002478_02857;MGYG000000029_01865;MGYG000003922_02460;MGYG000004797_02704;MGYG000000196_04520;MGYG000002549_02752;MGYG000002455_03369;MGYG000001378_02161;MGYG000001337_03642;MGYG000001789_01388;MGYG000000236_00439;MGYG000000243_00157;MGYG000000224_01030;MGYG000001599_01157;MGYG000003681_01115;MGYG000001345_00472;MGYG000002171_02202;MGYG000001313_02629;MGYG000000098_00880;MGYG000004876_02774;MGYG000001306_03183 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,4AQJI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 mce 1.0 - 1.0 5.1.99.1 1.0 ko:K05606 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R02765,R09979 1.0 RC00780,RC02739 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glyoxalase_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004185_00877 0.041666666666666664 methylmalonyl-CoA epimerase. methylmalonyl coenzyme A racemase. - (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K05606:MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242244 0 488062 0 0 0 0 0 0 0 0 0 0 780471 0 0 0 0 0 0 0 0 0 0 0 0 0 567074 0 0 0 0 0 0 0 0 0 0 331109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469149 0 0 0 0 0 0 0 0 0 0 0 0 148927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307242 0 +(Pyro-carbamidomethyl)CYNIETVEDQKVK MGYG000002470_02013;MGYG000002478_02857;MGYG000004797_02704;MGYG000002455_03369;MGYG000004876_02774;MGYG000001306_03183 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,4AQJI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 mce 1.0 - 1.0 5.1.99.1 1.0 ko:K05606 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R02765,R09979 1.0 RC00780,RC02739 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glyoxalase_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002470_02013 0.16666666666666666 methylmalonyl-CoA epimerase. methylmalonyl coenzyme A racemase. - (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K05606:MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] 1.0 none 1.0 1107386 0 1080203 0 0 1525760 0 757378 1423476 1230565 0 0 0 1305984 0 2237870 1818339 1518340 0 1514872 0 1373298 1194981 1893216 0 1273125 0 1014775 0 0 0 0 1419877 647104 0 0 1050609 1178590 1048176 0 1498508 0 0 1252171 0 1223502 1251331 990578 0 0 0 1304573 0 1865894 1117271 706464 0 0 0 1630852 1050183 1100292 0 1121561 0 932397 0 0 0 0 1227903 391629 0 0 0 1057903 492146 0 840102 0 0 748530 0 0 798649 708276 0 0 0 589386 0 867480 614639 1095603 0 573044 0 498443 830375 746285 0 462663 0 788243 0 0 0 0 487702 0 0 0 522775 744951 381990 0 0 0 0 427847 0 335564 365711 664582 0 0 0 473248 0 473720 298821 0 0 432094 0 404543 289592 409250 0 470420 0 0 0 0 0 0 334161 375404 0 0 373744 238898 1001135 0 1356666 0 0 1620223 0 979519 1670105 796461 0 0 0 867323 0 982051 1550186 1749334 0 1200418 0 1311032 1644895 1488553 0 1647249 0 1463837 0 0 0 0 1112694 1948015 0 0 1547685 2017287 +(Pyro-carbamidomethyl)CYNIETVEDQKVR MGYG000004185_00877;MGYG000001661_01872;MGYG000001346_02849;MGYG000000029_01865;MGYG000003922_02460;MGYG000000196_04520;MGYG000002549_02752;MGYG000001337_03642;MGYG000001378_02161;MGYG000000236_00439;MGYG000000243_00157;MGYG000000224_01030;MGYG000001599_01157;MGYG000003681_01115;MGYG000001345_00472;MGYG000002171_02202;MGYG000001313_02629;MGYG000000098_00880;MGYG000001370_00016 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0346@1|root,COG0346@2|Bacteria,4NNGG@976|Bacteroidetes,2FRZS@200643|Bacteroidia,4AQJI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 mce 1.0 - 1.0 5.1.99.1 1.0 ko:K05606 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R02765,R09979 1.0 RC00780,RC02739 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glyoxalase_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004185_00877 0.05263157894736842 methylmalonyl-CoA epimerase. methylmalonyl coenzyme A racemase. - (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K05606:MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] 1.0 none 1.0 1186782 1539080 0 0 1746812 1563453 998182 1912450 1281646 0 1927461 1177427 0 0 0 1788227 2089097 1098204 0 0 0 1194705 1222665 1240026 1121274 1528458 0 1189826 0 490702 1984687 1319249 3339398 1889724 0 1455973 1631081 3035265 1006001 698431 1131390 0 1977902 1072847 962282 1474494 1061334 0 1962916 1755030 0 0 0 1272750 1106373 0 0 0 0 1297017 0 873529 1147636 1364801 1110952 0 0 672997 677355 1422780 1044800 988344 0 809950 865214 1195169 1552687 1068797 1741210 0 1930937 1461021 1610853 1136763 1441292 0 1470087 1679268 0 0 0 1249084 882318 1756132 0 0 0 994553 1499860 1223900 860524 1260607 1152370 1326245 0 1013333 1400963 1098408 1169466 981092 0 1510913 1245642 1276570 999612 841219 846408 0 814576 796738 833059 1065853 1323279 0 861647 914983 0 0 0 1235634 899782 729043 0 0 0 778781 846652 759233 1117631 1649099 1311781 387304 0 1090919 677574 1072564 935568 1724421 0 1241119 1007608 674908 497953 258919 563163 0 518136 995052 509331 436675 753358 0 1177889 628967 0 0 0 299390 568905 0 0 0 0 822141 0 849774 706733 656458 499032 648065 0 673400 561514 592727 525170 602345 0 535601 950350 550565 +(Pyro-carbamidomethyl)CYYFGGGDDGSMR MGYG000000198_04292 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04292 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283760 0 0 0 0 0 0 0 0 0 0 0 1547429 0 0 0 0 0 0 0 0 1829612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1489491 0 0 0 0 +(SMA)AALENK MGYG000001630_00344;MGYG000003460_00376;MGYG000003460_01250 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotellamassilia 1.0 COG0539@1|root,COG0539@2|Bacteria,4NDW9@976|Bacteroidetes,2FNZK@200643|Bacteroidia,1WD2N@1283313|Alloprevotella 0.6666666666666666 976|Bacteroidetes 1.0 J 0.6666666666666666 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 0.6666666666666666 rpsA 0.6666666666666666 - 1.0 - 0.6666666666666666 ko:K02945 0.6666666666666666 ko03010,map03010 0.6666666666666666 M00178 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 br01610,ko00000,ko00001,ko00002,ko03011 0.6666666666666666 - 1.0 - 1.0 - 1.0 S1 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001630_00344 0.3333333333333333 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Ribosome 0.6666666666666666 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3843425 0 0 0 0 0 0 +(SMA)AC(Carbamidomethyl)AAANVLLK MGYG000002506_04111 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3ZJCJ@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 F 1.0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 deoA 1.0 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 1.0 2.4.2.4 1.0 ko:K00758 1.0 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 1.0 - 1.0 R01570,R02484,R08222,R08230 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 1.0 Glycos_trans_3N,Glycos_transf_3,PYNP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04111 1.0 thymidine phosphorylase. pyrimidine phosphorylase. In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.-!-Formerly EC 2.4.2.23. phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Bladder cancer 1.0 K00758:deoA, TYMP; thymidine phosphorylase [EC:2.4.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1027031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 855825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(SMA)APAPQTVPDAVETLKR MGYG000003681_01829 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0584@1|root,COG0584@2|Bacteria,4NHVM@976|Bacteroidetes,2FNEP@200643|Bacteroidia,4AP34@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Glycerophosphoryl diester phosphodiesterase family 1.0 glpQ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GDPD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_01829 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(SMA)ENLDIAGMMNVLNKK MGYG000000184_01511;MGYG000001338_01460;MGYG000000200_00890 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_01511 0.3333333333333333 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286091 0 0 0 0 0 0 +(SMA)GISKDVNKGIELAEQLAAALGGGVVGASR MGYG000000022_01320 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WGKC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4,Fer4_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01320 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2417872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(SMA)IGPHTDVPAGDIGVGAR MGYG000002195_01526 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Anaerovoracaceae|g__Emergencia|s__Emergencia sp900551775|m__MGYG000002195 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WCGW@538999|Clostridiales incertae sedis 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.2,1.4.1.3,1.4.1.4 1.0 ko:K00260,ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00430,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00430,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002195_01526 1.0 glutamate dehydrogenase. | glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). | (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Taurine and hypotaurine metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00260:gudB, rocG; glutamate dehydrogenase [EC:1.4.1.2]|K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4646720 0 0 0 0 0 0 0 2836864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(SMA)INTVEELC(Carbamidomethyl)NR MGYG000000133_00101 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3XYUC@572511|Blautia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 - 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00101 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1516653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2568194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(SMA)LAERVAGNVVENFEDIDKAPEER MGYG000001338_03373 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03373 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 821107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2668794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(SMA)LLDEGEAGDNVGLLLR MGYG000004757_00594;MGYG000002930_00867;MGYG000003170_00035;MGYG000002905_00001;MGYG000000053_00908;MGYG000004006_00433;MGYG000002762_01733;MGYG000004848_00666;MGYG000000074_01773;MGYG000003460_01161;MGYG000000215_00564;MGYG000001925_01419;MGYG000001302.1_00073;MGYG000003202_00129;MGYG000000357_02040;MGYG000003992_01709;MGYG000002556_01332;MGYG000004658_01205;MGYG000003446_00658;MGYG000003170_00048;MGYG000002540_03367;MGYG000001763_00317;MGYG000000254_02569;MGYG000000348_00283;MGYG000003279_00951 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.32 976|Bacteroidetes 0.92 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004757_00594 0.04 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 233631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 570014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(SMA)TILEAVAK MGYG000002494_04513 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0013@1|root,COG0013@2|Bacteria,1MU9A@1224|Proteobacteria,1RMWZ@1236|Gammaproteobacteria,3ZKEI@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iECABU_c1320.ECABU_c29670,iECED1_1282.ECED1_3146,iEcHS_1320.EcHS_A2833,iJN746.PP_4474 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04513 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01872:AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7] 1.0 none 1.0 92982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 621538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663168 0 0 0 0 0 0 0 0 0 0 0 0 169886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(SMA)TWINEK MGYG000000146_01791 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea|s__Dorea formicigenerans|m__MGYG000000146 1.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Mannitol dehydrogenase 1.0 - 1.0 - 1.0 1.1.1.58 1.0 ko:K00041 1.0 ko00040,ko01100,map00040,map01100 1.0 M00631 1.0 R02555 1.0 RC00085 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Mannitol_dh,Mannitol_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000146_01791 1.0 tagaturonate reductase. Tagaturonate dehydrogenase. - D-altronate + NAD(+) = H(+) + keto-D-tagaturonate + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Metabolic pathways 1.0 K00041:uxaB; tagaturonate reductase [EC:1.1.1.58] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14989701 0 0 0 0 14727433 0 0 0 0 11769580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70639965 0 0 0 0 85263100 0 0 0 0 70232764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4939733 0 0 0 0 2991734 0 0 0 0 3107105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 27260151 0 0 0 0 43246479 0 0 0 0 23540343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12105496 0 0 0 0 10859023 0 0 0 0 7880289 0 0 0 0 0 0 0 0 0 0 +(SMA)VELAGYLDSYIPEPER MGYG000002535_04656 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter|s__Citrobacter gillenii|m__MGYG000002535 1.0 COG0050@1|root,COG0050@2|Bacteria,1MVC0@1224|Proteobacteria,1RMYX@1236|Gammaproteobacteria,3ZITI@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002535_04656 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15626670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(SMA)VVLNIPMMSAAMDTVTEHR MGYG000002517_01047 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01047 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(SPITC_13C(6))AKQAALAAAVK MGYG000001338_03293 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Radical SAM domain protein 1.0 atsB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,Radical_SAM,SPASM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03293 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 908588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2293671 0 0 0 0 0 0 +(Succinyl)AADPAAQFEGLK MGYG000000133_00205 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00205 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739547 0 0 0 0 0 0 0 0 1918878 0 0 0 0 0 0 0 0 0 0 +(Succinyl)AEDYLGQEVTEAVITVPAYFSDSQR MGYG000004876_01872;MGYG000000196_01218;MGYG000000243_00100;MGYG000002478_02522 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,4ANVI@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004876_01872 0.25 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Succinyl)GMEAVYTLLNIDR MGYG000001300_00435 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia,3WGYT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 MCRA family 1.0 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00435 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 - 1.0 K10254:ohyA, sph; oleate hydratase [EC:4.2.1.53] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Succinyl)KAAIGIPEEELR MGYG000000196_04526;MGYG000002478_01776;MGYG000002905_01187;MGYG000002033_00099;MGYG000000243_02506 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.6 976|Bacteroidetes 1.0 G 0.6 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.6 fba 0.6 - 1.0 4.1.2.13 0.6 ko:K01624 0.6 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6 M00001,M00003,M00165,M00167,M00344,M00345 0.6 R01068,R01070,R01829,R02568 0.6 RC00438,RC00439,RC00603,RC00604 0.6 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04526 0.2 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6 0.6 0.6 0.6 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 0.6 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1914145 0 0 2419123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Succinyl)LRGLYEGVLTGK MGYG000002298_00811;MGYG000002528_01412;MGYG000000201_03244;MGYG000000142_02223;MGYG000004839_02530;MGYG000003012_01963;MGYG000000095_00309;MGYG000000164_00589;MGYG000004055_01618;MGYG000002279_01299;MGYG000002042_01497;MGYG000000404_01723;MGYG000002517_02750 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.6153846153846154 186801|Clostridia 0.9230769230769231 C 0.7692307692307693 Belongs to the Glu Leu Phe Val dehydrogenases family 0.7692307692307693 gdhA 0.9230769230769231 - 1.0 1.4.1.3,1.4.1.4 0.8461538461538461 ko:K00261,ko:K00262 0.8461538461538461 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.8461538461538461 M00740 0.9230769230769231 R00243,R00248 0.9230769230769231 RC00006,RC02799 0.9230769230769231 ko00000,ko00001,ko00002,ko01000,ko04147 0.9230769230769231 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.9230769230769231 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_00811 0.07692307692307693 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.8461538461538461 0.8461538461538461 0.8461538461538461 0.8461538461538461 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.8461538461538461 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.8461538461538461 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Succinyl)NKLDANDPEYLQKR MGYG000000262_02730 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02730 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7346893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20545860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 186269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Succinyl)TQNQELLDFTAR MGYG000000098_00811 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides bouchesdurhonensis|m__MGYG000000098 1.0 COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,2FM28@200643|Bacteroidia,4AN5I@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 acd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_dehyd_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000098_00811 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 1012583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Succinyl_13C(4))EMSFEQMLEESFK MGYG000002517_01648;MGYG000000271_00477 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,21Z6B@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01648 0.5 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1|K03527:ispH, lytB; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4608124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Succinyl_2H(4))AIGSMGGALSNVPAAELGAVVIK MGYG000002485_00796 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0183@1|root,COG0183@2|Bacteria,378R0@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 I 1.0 Belongs to the thiolase family 1.0 - 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_00796 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44732004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37087729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Succinyl_2H(4))AYELEGSIEDKLNQIVQK MGYG000001338_00681 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Belongs to the formate--tetrahydrofolate ligase family 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_00681 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01938:fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Succinyl_2H(4))NLVDAIYAC(Carbamidomethyl)HDGVLR MGYG000002293_00847 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FM0V@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Xaa-His dipeptidase 1.0 pepD_2 1.0 - 1.0 - 1.0 ko:K01270 1.0 ko00480,ko01100,map00480,map01100 1.0 - 1.0 R00899,R04951 1.0 RC00096,RC00141 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00847 1.0 - - - - 1.0 1.0 1.0 1.0 Glutathione metabolism|Metabolic pathways 1.0 K01270:pepD; dipeptidase D [EC:3.4.13.-] 1.0 none 1.0 0 0 283279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9539589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Sulfo-NHS-LC-LC-Biotin)AMTAFQPDVIIALGGGSAMDAGK MGYG000001619_01035 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA9502|s__UBA9502 sp900540335|m__MGYG000001619 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,2686V@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001619_01035 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Sulfo-NHS-LC-LC-Biotin)DGAAQR MGYG000004828_01576;MGYG000002485_02480;MGYG000004893_01506 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004828_01576 0.3333333333333333 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5330257 0 0 0 0 6852654 0 0 6536640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7643205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37495 0 0 0 0 0 0 0 0 0 0 0 +(Sulfo-NHS-LC-LC-Biotin)EGGHYGDLYVR MGYG000002478_01405;MGYG000001489_02235;MGYG000004797_04333;MGYG000002203_01195 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKS4@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01405 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 655880 0 0 0 0 0 0 0 0 0 228587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1507622 0 0 0 0 1769465 0 0 0 0 1250669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458566 0 0 0 0 1854172 0 0 0 0 260535 0 0 0 0 0 0 0 0 0 0 +(Sulfo-NHS-LC-LC-Biotin)VFGGMTSHAAVVAR MGYG000003891_00830 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000003891_00830 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192238 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Sulfo-NHS-LC-LC-Biotin)YPVATRLSLNGTIIVGR MGYG000002478_01945;MGYG000000243_02673;MGYG000000236_04233;MGYG000002455_02631 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,4NE85@976|Bacteroidetes,2FNPE@200643|Bacteroidia,4AKTC@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 C 1.0 Catalyzes the reversible hydration of fumarate to (S)- malate 1.0 fumB 1.0 - 1.0 4.2.1.2 1.0 ko:K01676 1.0 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00374 1.0 R01082 1.0 RC00443 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fumerase,Fumerase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01945 0.25 fumarate hydratase. fumarase. - (S)-malate = fumarate + H2O. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01676:E4.2.1.2A, fumA, fumB; fumarate hydratase, class I [EC:4.2.1.2] 1.0 none 1.0 0 0 234425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154685 0 298459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293522 0 196417 0 0 0 0 212762 0 0 716873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 764972 0 150122 0 0 0 0 934090 +(TMAB)DMPFLMPVEDVFTISGR MGYG000002057_01066;MGYG000003819_01356;MGYG000003266_00955;MGYG000004475_00887;MGYG000001086_01249;MGYG000002794_01318;MGYG000002926_00232 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,2N71Q@216572|Oscillospiraceae 0.7142857142857143 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002057_01066 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 9967781 0 0 0 14090011 0 0 0 0 0 14573816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14888773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3078057 0 0 0 0 0 5787709 0 0 3658513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4955352 0 0 0 0 0 0 0 0 0 0 14636194 0 0 0 0 0 0 0 0 0 0 14578012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMAB)GEMNFDVVIASPDAMR MGYG000002506_03690;MGYG000002494_02478 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,3WVKV@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_03690 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 315865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 750578 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMAB)HGYVCDVTDEPAVQAMVATIAK MGYG000000013_04699 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp902362375|m__MGYG000000013 1.0 COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,2FMSH@200643|Bacteroidia,4AKTZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Oxidoreductase, short chain dehydrogenase reductase family protein 1.0 idnO 1.0 - 1.0 1.1.1.69 1.0 ko:K00046 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_04699 1.0 gluconate 5-dehydrogenase. 5-ketogluconate reductase. - (1) D-gluconate + NADP(+) = 5-dehydro-D-gluconate + H(+) + NADPH. (2) D-gluconate + NAD(+) = 5-dehydro-D-gluconate + H(+) + NADH. 1.0 1.0 1.0 1.0 - 1.0 K00046:idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMAB)SNEALGMVETK MGYG000000198_03138 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,2235C@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 CQ 1.0 BMC domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_03138 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6550003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2365264 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11787884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7095634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1808437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMAB)TSVEDATVPAWLELDR MGYG000002485_02438 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia,36DJ1@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 S 1.0 Amidohydrolase family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_02438 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490735 0 0 0 0 532308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMAB)VAEGALSETHSILQR MGYG000002517_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00135 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMT)PAEDIVSKDVFDAAVR MGYG000004797_03291;MGYG000002478_00220 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,4AMRT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 GK 1.0 Psort location Cytoplasmic, score 9.26 1.0 glk 1.0 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_03291 0.5 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Galactose metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Neomycin, kanamycin and gentamicin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00845:glk; glucokinase [EC:2.7.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2403438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1078464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMT)TISTNLSAQR MGYG000003363_02129 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900766195|m__MGYG000003363 1.0 COG1629@1|root,COG3188@1|root,COG1629@2|Bacteria,COG3188@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4ANM7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 NPU 1.0 Psort location OuterMembrane, score 9.49 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003363_02129 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMT)VDSEALADAVEAGK MGYG000000177_00811 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,249PP@186801|Clostridia,36DQS@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CH 1.0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 ldhA 1.0 - 1.0 1.1.1.28 1.0 ko:K03778 1.0 ko00620,ko01120,map00620,map01120 1.0 - 1.0 R00704 1.0 RC00044 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C,PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000177_00811 1.0 D-lactate dehydrogenase. D-lactic dehydrogenase. - (R)-lactate + NAD(+) = H(+) + NADH + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Microbial metabolism in diverse environments 1.0 K03778:ldhA; D-lactate dehydrogenase [EC:1.1.1.28] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMT2plex)DEGEAGDNVGLLLR MGYG000004757_00594;MGYG000000254_02569;MGYG000002905_00001;MGYG000004658_01205;MGYG000001302.1_00073;MGYG000003202_00129;MGYG000004006_00433 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.42857142857142855 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004757_00594 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMT2plex)DLNAASIEAAMSMIAGTAR MGYG000000099_00105;MGYG000000142_01260 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,2N790@216572|Oscillospiraceae 0.5 186801|Clostridia 1.0 J 1.0 50S ribosomal protein L11 0.5 rplK 1.0 - 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_00105 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02867:RP-L11, MRPL11, rplK; large subunit ribosomal protein L11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 52581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMT2plex)PVEDVFSITGR MGYG000004757_00594;MGYG000000127_03982;MGYG000000196_03974;MGYG000002905_00001;MGYG000001338_03373;MGYG000002098_00731;MGYG000000142_00171;MGYG000001789_00154;MGYG000000236_01807;MGYG000004763_01689;MGYG000002098_01616;MGYG000000098_02017;MGYG000000164_01096;MGYG000004642_00846;MGYG000003202_00129;MGYG000000919_01815;MGYG000001558_01002;MGYG000001310_01963;MGYG000003185_01053;MGYG000003185_01074;MGYG000001415_02515;MGYG000002438_02321;MGYG000004658_01205;MGYG000000193_02083;MGYG000000243_01988;MGYG000000013_02251;MGYG000001780_03476;MGYG000001562_01075;MGYG000002286_02469;MGYG000000216_02406;MGYG000003279_00951;MGYG000003812_01875 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.21875 976|Bacteroidetes 0.5 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.96875 tuf 1.0 - 0.875 - 1.0 ko:K02358 0.9375 - 0.9375 - 0.9375 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9375 - 0.9375 - 1.0 - 0.90625 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004757_00594 0.03125 - - - - 1.0 1.0 1.0 1.0 - 0.9375 K02358:tuf, TUFM; elongation factor Tu 0.9375 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5234027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 74496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28974496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMT6plex)AGAANIVPNSTGAAK MGYG000001311_02933;MGYG000004087_02290;MGYG000001558_01857;MGYG000001688_03910;MGYG000000278_03657;MGYG000000036_01872;MGYG000000362_01155;MGYG000003001_00320;MGYG000000258_00590;MGYG000000145_03615;MGYG000001606_02632;MGYG000000089_01653;MGYG000000909_00644;MGYG000004691_00618;MGYG000003510_00403;MGYG000003465_00706;MGYG000000179_02084;MGYG000002155_00766;MGYG000000193_03247;MGYG000001707_00061;MGYG000003431_01105;MGYG000000690_01295;MGYG000002683_02093;MGYG000002258_00386;MGYG000001954_02254;MGYG000001619_01736;MGYG000002638_00362;MGYG000000463_00862;MGYG000001065_01088;MGYG000001757_00726;MGYG000002946_02881;MGYG000000150_00838;MGYG000000433_00630;MGYG000003656_01296;MGYG000004810_01402;MGYG000004789_01485;MGYG000000242_02076;MGYG000004815_01345;MGYG000004884_01637;MGYG000001493_05257;MGYG000002052_00078;MGYG000000392_01140;MGYG000000231_00608;MGYG000000836_00852;MGYG000000198_04065 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.4222222222222222 186801|Clostridia 0.9111111111111111 C 0.7333333333333333 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5333333333333333 gap 1.0 - 0.9333333333333333 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001311_02933 0.022222222222222223 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMT6plex)DLRELMNIPDNYK MGYG000002492_01710 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01710 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Vitamin B6 metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00831:serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 186615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TMT6plex)EGLSPCETGIFLETAHPAK MGYG000002478_02214 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0498@1|root,COG0498@2|Bacteria,4NEAA@976|Bacteroidetes,2FMPH@200643|Bacteroidia,4AKDS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Threonine synthase 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02214 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 856632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 812175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1319190 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 842381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3620596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TNBS)NETATASLAILK MGYG000003425_00283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-127|s__CAG-127 sp900766925|m__MGYG000003425 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Threonine synthase 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003425_00283 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6425728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(TNBS)PVLTPADIIDAR MGYG000004464_01448 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Barnesiellaceae|g__Barnesiella|s__Barnesiella sp900542255|m__MGYG000004464 1.0 COG0714@1|root,COG0714@2|Bacteria,4NDVZ@976|Bacteroidetes,2FMGP@200643|Bacteroidia,22W2U@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 ATPase family associated with various cellular activities (AAA) 1.0 moxR 1.0 - 1.0 - 1.0 ko:K03924 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004464_01448 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03924:moxR; MoxR-like ATPase [EC:3.6.3.-] 1.0 none 1.0 1128297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 966087 0 0 0 0 0 0 0 0 0 0 1249607 0 +(Triton)DFDSIDNAPEEKER MGYG000003542_01415 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900769445|m__MGYG000003542 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003542_01415 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Triton)LALFPLSTEGWAEQR MGYG000002478_01404 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01404 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 6678575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_210)SYGMLMTDILPARDDQGR MGYG000002478_00647 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKGC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02014 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00647 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02014:TC.FEV.OM; iron complex outermembrane recepter protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)AGVTKEDINAAMK MGYG000003694_01737;MGYG000001311_02933;MGYG000001186_01925;MGYG000001065_01088;MGYG000000271_03250;MGYG000004271_00554;MGYG000000404_00344;MGYG000001493_05257;MGYG000002517_01026;MGYG000000179_02084;MGYG000002492_01379;MGYG000000489_00503;MGYG000000198_04065 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6153846153846154 186801|Clostridia 1.0 G 0.6153846153846154 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.6153846153846154 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320634 0 0 324667 0 458690 0 0 0 460221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505441 0 0 0 0 0 0 0 0 0 361218 0 0 0 0 0 0 415180 0 0 0 0 0 0 805347 0 788327 0 0 0 0 341327 0 770716 0 0 0 662305 973477 0 0 0 0 0 0 0 0 0 0 0 270552 0 0 0 0 0 0 0 359718 456950 0 0 377467 0 821118 180454 0 0 272798 0 0 0 0 0 0 397169 0 1674490 0 3118574 0 0 1707082 1464190 0 2338618 3196039 0 1690340 0 0 1891115 0 3340711 0 1971756 1528858 1885366 0 0 1277748 0 889945 2009816 0 0 1437325 1293380 0 2140934 0 0 1528979 1049934 1050945 +(Unknown_216)AVVDAGWKPR MGYG000000080_01477 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_01477 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 630182 0 0 0 0 0 0 0 0 0 +(Unknown_216)AYTGDQMTLDGPQRK MGYG000003694_01737;MGYG000000038_02185;MGYG000001607_01815;MGYG000001310_02090;MGYG000000249_01352;MGYG000000205_02269;MGYG000000262_01195;MGYG000000140_01181;MGYG000002528_00367;MGYG000000223_00996;MGYG000001711_02099;MGYG000002279_00557;MGYG000001496_01122;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000002966_00075;MGYG000000404_00344;MGYG000003335_00316;MGYG000000233_00345;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000252_01324;MGYG000000077_00219;MGYG000002945_00682;MGYG000000312_01508;MGYG000004610_00503;MGYG000004740_01468;MGYG000002212_00259;MGYG000004296_01958;MGYG000000213_00374;MGYG000002517_01026;MGYG000000142_01979;MGYG000001299_00204;MGYG000004707_01697;MGYG000000251_00555;MGYG000000212_01474;MGYG000002974_01418;MGYG000004785_01017;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001338_02547;MGYG000000133_02283;MGYG000002298_02410;MGYG000001315_01699;MGYG000000153_00303;MGYG000000489_00503 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5490196078431373 186801|Clostridia 0.9215686274509803 C 0.7058823529411765 Psort location Cytoplasmic, score 0.5882352941176471 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.0196078431372549 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284043 0 0 0 0 0 0 0 0 0 0 0 0 468487 0 0 0 0 0 0 0 901041 0 0 0 0 1187179 815051 0 0 0 0 859870 0 0 0 0 1307250 903277 0 0 0 0 0 0 0 0 0 0 752074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)DKPFLMPIEDVFTITGR MGYG000000255_02009 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,27W01@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_02009 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)FNPDGTLDR MGYG000001637_02230;MGYG000001367_03001;MGYG000001615_04300;MGYG000003074_00586;MGYG000002141_01824;MGYG000000356_02130;MGYG000000489_01026;MGYG000001617_02046;MGYG000000080_01476;MGYG000002278_01894;MGYG000004719_02002;MGYG000000997_00555;MGYG000001777_01059;MGYG000000312_02426;MGYG000002445_02276;MGYG000002528_02668;MGYG000003702_03102;MGYG000004359_01906;MGYG000000028_00944;MGYG000000271_02101;MGYG000000404_01798;MGYG000000398_00614;MGYG000002492_00660;MGYG000000154_01281;MGYG000002517_00543;MGYG000003486_02521;MGYG000001319_02234;MGYG000000217_01341 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.5357142857142857 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.5357142857142857 etfB 1.0 - 0.9642857142857143 - 0.8571428571428571 ko:K03521 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.8571428571428571 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.03571428571428571 - - - - 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.8571428571428571 none 1.0 0 0 0 0 0 0 0 0 314703 296493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492314 0 0 0 0 0 0 0 0 0 0 763729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 655279 590078 0 0 0 0 0 0 0 0 0 271176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)IFGPVAR MGYG000002560_00246;MGYG000004396_01391;MGYG000000121_02203;MGYG000003921_00353;MGYG000000136_02068;MGYG000003899_00624;MGYG000002965_00668;MGYG000000405_00842;MGYG000002393_00685;MGYG000002418_00868;MGYG000000243_01961;MGYG000003367_01234;MGYG000000133_00055;MGYG000003694_02438;MGYG000004732_00524;MGYG000001835_01798;MGYG000001604_00189;MGYG000003420_00101;MGYG000004769_00449;MGYG000002720_00272;MGYG000004733_00978;MGYG000002291_02245;MGYG000001447_01054;MGYG000002619_02376;MGYG000002670_00396;MGYG000003073_00057;MGYG000000105_02014;MGYG000000301_00170;MGYG000001754_00741;MGYG000004006_01212;MGYG000004158_01541;MGYG000001616_02247;MGYG000002148_03767;MGYG000000159_01021;MGYG000001925_01442;MGYG000000184_01182;MGYG000001615_01739;MGYG000000272_00835;MGYG000003374_01451;MGYG000002835_00986;MGYG000001789_00120;MGYG000000198_04897;MGYG000000074_01952;MGYG000000802_00713;MGYG000002057_00243;MGYG000001338_02797;MGYG000001637_00021;MGYG000003142_01853;MGYG000004763_00936;MGYG000000216_02353;MGYG000004735_01591;MGYG000000696_01653;MGYG000003012_01779;MGYG000002935_01249;MGYG000003375_01792;MGYG000003346_00191;MGYG000000911_00434;MGYG000001367_00359;MGYG000000462_00473;MGYG000003273_00547;MGYG000000414_01234;MGYG000003013_00823;MGYG000001186_01102;MGYG000002963_00444;MGYG000000022_02030;MGYG000000205_02194;MGYG000000144_01704;MGYG000000274_01727;MGYG000000016_01671;MGYG000002250_00105;MGYG000000212_03057;MGYG000003937_00257;MGYG000002156_01360;MGYG000003074_00525;MGYG000000084_01012;MGYG000003266_00870;MGYG000002145_00328;MGYG000002925_00079;MGYG000002944_01730;MGYG000000080_02265;MGYG000003539_00301;MGYG000004019_02165;MGYG000002218_02510;MGYG000001619_00824;MGYG000002065_01089;MGYG000002290_02014;MGYG000004479_01422;MGYG000001627_01322;MGYG000000222_02479;MGYG000002298_00338;MGYG000003355_02352;MGYG000001439_02153;MGYG000002651_00738;MGYG000002834_00450;MGYG000000213_00204;MGYG000002820_00726;MGYG000000002_00872;MGYG000000252_01809;MGYG000000208_01759;MGYG000002545_01130;MGYG000000271_01071;MGYG000001477_00028;MGYG000000263_01425;MGYG000001310_00097;MGYG000001562_01955;MGYG000004475_01148;MGYG000001776_00078;MGYG000000031_02256;MGYG000000145_02799;MGYG000002492_00385;MGYG000001255_02123;MGYG000000179_04590;MGYG000002737_01338;MGYG000000053_00703;MGYG000002716_01485;MGYG000001346_01509;MGYG000004848_00703;MGYG000001975_01106;MGYG000001733_00023;MGYG000003282_01790;MGYG000002485_02421;MGYG000004271_00026;MGYG000001636_00356;MGYG000001502_00402;MGYG000002279_01062;MGYG000002978_01109;MGYG000000195_02123;MGYG000000138_02879;MGYG000000356_00514;MGYG000002082_00477;MGYG000002945_02574;MGYG000002610_01884;MGYG000000095_00564;MGYG000000185_02307;MGYG000002040_00980;MGYG000002989_00867;MGYG000002753_00203;MGYG000003166_00769;MGYG000002517_02863;MGYG000001672_00432;MGYG000000050_01182;MGYG000001444_01646;MGYG000002224_01650;MGYG000002312_02267;MGYG000002272_00461;MGYG000003241_00581;MGYG000002845_00988;MGYG000000233_02353;MGYG000002202_01349;MGYG000004124_01028;MGYG000000042_01081;MGYG000003268_00796;MGYG000001315_01346;MGYG000001056_01159;MGYG000001364_02744;MGYG000000143_00634;MGYG000000039_01695;MGYG000002274_00835;MGYG000004680_02469;MGYG000003519_00370;MGYG000002836_03711;MGYG000000181_01082;MGYG000000781_00858;MGYG000002108_01883;MGYG000003697_01458;MGYG000001464_01860;MGYG000002059_00502;MGYG000001613_01098;MGYG000002438_02218;MGYG000000142_02057;MGYG000003422_00856;MGYG000004833_01895;MGYG000001531_03077;MGYG000000776_00450;MGYG000004828_02406;MGYG000003274_01538;MGYG000000223_03149;MGYG000000273_00396;MGYG000002203_01157;MGYG000000201_02091;MGYG000002154_01340;MGYG000004140_01825;MGYG000004784_00626;MGYG000000224_00466;MGYG000000164_02754;MGYG000002966_02565;MGYG000002115_00719;MGYG000003984_01595;MGYG000004468_00447;MGYG000002775_00023;MGYG000002854_00099;MGYG000003147_00990;MGYG000002641_00978;MGYG000002954_00797;MGYG000002795_00406;MGYG000000806_01293;MGYG000003695_00642;MGYG000001157_01268;MGYG000001970_02200;MGYG000004464_01257;MGYG000001199_01758;MGYG000002794_00549;MGYG000000489_01448;MGYG000002603_01757;MGYG000004569_00147;MGYG000004469_01431;MGYG000004487_01012;MGYG000002777_00379;MGYG000002563_00497;MGYG000002080_00551;MGYG000004716_01212;MGYG000004565_00400;MGYG000002050_01544;MGYG000000054_03868;MGYG000001543_00407;MGYG000002234_01451;MGYG000000215_01904;MGYG000001306_02670 domain d__Bacteria 1.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,36IUH@31979|Clostridiaceae 0.2798165137614679 186801|Clostridia 0.6055045871559633 J 1.0 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome 1.0 rplN 1.0 - 0.7018348623853211 - 1.0 ko:K02874 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L14 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002560_00246 0.0045871559633027525 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02874:RP-L14, MRPL14, rplN; large subunit ribosomal protein L14 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461843 0 0 0 0 0 0 0 0 579546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1142762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1841183 0 0 0 0 0 0 0 0 1293280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)IVGDGIAIKPTGNK MGYG000002507_04262;MGYG000003390_03803;MGYG000002494_03971;MGYG000002506_01939;MGYG000000093_00708;MGYG000002534_03519;MGYG000002504_02873;MGYG000000235_01040;MGYG000003365.1_02703;MGYG000002477_02073;MGYG000002500_03419;MGYG000002535_01116;MGYG000002515_00713;MGYG000002323_02957 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2190@1|root,COG2190@2|Bacteria,1MWIQ@1224|Proteobacteria,1RNE3@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 G 1.0 pts system 1.0 crr 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009892,GO:0009898,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019222,GO:0019897,GO:0019898,GO:0031234,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045912,GO:0048519,GO:0050789,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071944,GO:0080090,GO:0098552,GO:0098562 1.0 - 1.0 ko:K02777 1.0 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 1.0 M00265,M00266,M00268,M00270,M00272,M00303,M00806 1.0 R02738,R02780,R04111,R04394,R05132,R08559 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.1 1.0 - 1.0 e_coli_core.b2417,iAF1260.b2417,iAPECO1_1312.APECO1_4128,iB21_1397.B21_02278,iBWG_1329.BWG_2179,iE2348C_1286.E2348C_2603,iEC042_1314.EC042_2626,iEC55989_1330.EC55989_2707,iECABU_c1320.ECABU_c27380,iECBD_1354.ECBD_1264,iECB_1328.ECB_02317,iECDH10B_1368.ECDH10B_2582,iECDH1ME8569_1439.ECDH1ME8569_2351,iECD_1391.ECD_02317,iECED1_1282.ECED1_2861,iECH74115_1262.ECH74115_3648,iECIAI1_1343.ECIAI1_2475,iECIAI39_1322.ECIAI39_2563,iECNA114_1301.ECNA114_2494,iECO103_1326.ECO103_2936,iECO111_1330.ECO111_3147,iECO26_1355.ECO26_3470,iECOK1_1307.ECOK1_2734,iECS88_1305.ECS88_2607,iECSE_1348.ECSE_2708,iECSF_1327.ECSF_2281,iECSP_1301.ECSP_3365,iECUMN_1333.ECUMN_2739,iECW_1372.ECW_m2646,iEKO11_1354.EKO11_1311,iETEC_1333.ETEC_2530,iEcDH1_1363.EcDH1_1244,iEcE24377_1341.EcE24377A_2704,iEcHS_1320.EcHS_A2552,iEcSMS35_1347.EcSMS35_2572,iEcolC_1368.EcolC_1261,iG2583_1286.G2583_2949,iJO1366.b2417,iJR904.b2417,iLF82_1304.LF82_0357,iNRG857_1313.NRG857_12120,iSFV_1184.SFV_2469,iSF_1195.SF2472,iSFxv_1172.SFxv_2721,iSSON_1240.SSON_2506,iS_1188.S2618,iUMN146_1321.UM146_04535,iUMNK88_1353.UMNK88_3019,iUTI89_1310.UTI89_C2751,iWFL_1372.ECW_m2646,iY75_1357.Y75_RS12665,ic_1306.c2952 1.0 PTS_EIIA_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002507_04262 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Biofilm formation - Escherichia coli|Phosphotransferase system (PTS)|Biofilm formation - Vibrio cholerae 1.0 K02777:crr; sugar PTS system EIIA component [EC:2.7.1.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 771163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 566261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)LVEADNAVDIAHK MGYG000000077_00330 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum soehngenii|m__MGYG000000077 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 0 0 0 0 529957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 843461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1444966 0 0 0 489516 1865549 0 0 0 0 0 0 0 0 0 0 0 884695 0 0 316579 0 244290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)LVEADNAVDIAHKER MGYG000000077_00330 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum soehngenii|m__MGYG000000077 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 1.0 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 880675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)MTDLDLAGKR MGYG000002506_02523;MGYG000002494_04273;MGYG000002507_00704;MGYG000000093_02472;MGYG000002323_03392 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0126@1|root,KOG1367@2759|Eukaryota,37R6T@33090|Viridiplantae,3GA5G@35493|Streptophyta,4JDX3@91835|fabids 1.0 2759|Eukaryota 1.0 G 1.0 Belongs to the phosphoglycerate kinase family 1.0 - 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N,MS_channel,PGK,TM_helix,Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02523 0.2 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 625163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 867636 0 0 0 0 +(Unknown_216)MYAGFSTAEESNKR MGYG000004717_00702;MGYG000004769_01826;MGYG000004804_00343;MGYG000000591_01064;MGYG000002659_00371;MGYG000001626_00536;MGYG000001365_01210 class d__Bacteria|p__Firmicutes_C|c__Negativicutes 1.0 COG1884@1|root,COG1884@2|Bacteria,1TQAD@1239|Firmicutes,4H22W@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 bhbA 1.0 - 1.0 5.4.99.2 1.0 ko:K01848 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00375,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004717_00702 0.14285714285714285 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01848:E5.4.99.2A, mcmA1; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)NLFIPGKK MGYG000002293_02708;MGYG000003697_02283;MGYG000000272_01790;MGYG000002080_01422;MGYG000001920_01212;MGYG000001789_02670 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 0.6666666666666666 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_02708 0.16666666666666666 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 196221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82992 0 0 0 0 283225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 123911 0 0 0 0 100527 0 0 759234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356351 0 0 0 0 534625 0 0 145534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408948 0 0 0 0 0 +(Unknown_216)SFDQIDNAPEEKER MGYG000003152_01866;MGYG000002930_00867;MGYG000004588_00463;MGYG000004464_00178;MGYG000002603_01782;MGYG000001630_01142;MGYG000003374_00521;MGYG000003353_00058;MGYG000003424_00456;MGYG000003460_01161;MGYG000000215_00564;MGYG000001925_01419;MGYG000001806_01406;MGYG000002293_00521;MGYG000004763_01689;MGYG000003681_02037;MGYG000002291_02272;MGYG000003202_00129;MGYG000002080_00527;MGYG000001770_01653;MGYG000003992_01709;MGYG000002470_01245;MGYG000001313_00097;MGYG000004629_00424;MGYG000003691_01713;MGYG000001780_03476;MGYG000002540_03367;MGYG000003697_01485;MGYG000002455_03884;MGYG000001763_00317;MGYG000000254_02569;MGYG000003812_01875;MGYG000003497_00215;MGYG000001360_01239;MGYG000003535_00219;MGYG000002834_01866;MGYG000000673_00997 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4P1C5@976|Bacteroidetes,2FX1Q@200643|Bacteroidia 0.3783783783783784 976|Bacteroidetes 0.9459459459459459 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9459459459459459 tuf 1.0 - 0.9459459459459459 - 1.0 ko:K02358 0.9459459459459459 - 0.9459459459459459 - 0.9459459459459459 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9459459459459459 - 0.9459459459459459 - 1.0 - 0.9459459459459459 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003152_01866 0.02702702702702703 - - - - 1.0 1.0 1.0 1.0 - 0.9459459459459459 K02358:tuf, TUFM; elongation factor Tu 0.9459459459459459 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1872959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)SFDSIDNAPEEKER MGYG000000042_01421;MGYG000004756_01173;MGYG000000196_03974;MGYG000002905_00001;MGYG000000138_00665;MGYG000001661_02666;MGYG000000053_00908;MGYG000004006_00433;MGYG000002762_01733;MGYG000000074_01773;MGYG000001789_00154;MGYG000000273_00431;MGYG000000054_03933;MGYG000000236_01807;MGYG000003701_03123;MGYG000000098_02017;MGYG000001302.1_00073;MGYG000000170_00073;MGYG000001503_00139;MGYG000002281_02290;MGYG000004474_01617;MGYG000003546_00955;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000003446_00658;MGYG000001552_00984;MGYG000001346_01533;MGYG000000243_01988;MGYG000000013_02251;MGYG000001562_01075;MGYG000000348_00283;MGYG000003279_00951;MGYG000000414_00662;MGYG000001655_02933;MGYG000000044_01721;MGYG000002418_00753;MGYG000000117_01463;MGYG000000168_03211 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.025 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5810675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1751540 0 0 0 0 0 0 0 345657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2529036 0 1195237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4270017 3656809 974948 5751517 7943761 1945400 0 0 428596 0 4248310 751433 0 2105320 4300512 0 2509424 970780 0 2768394 2134090 2007131 1717727 1605060 0 3561852 1800555 2340075 4062260 2608913 3214250 5607364 0 3407675 2432903 1387527 3703631 0 +(Unknown_216)SSASFGYNEDPIVSSDVIGMR MGYG000003465_00706 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__CAG-272|g__CAG-841|s__CAG-841 sp900544285|m__MGYG000003465 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003465_00706 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)TSIFDAK MGYG000004468_00660;MGYG000002540_02142;MGYG000004734_01400;MGYG000001783_01519;MGYG000003457_01802;MGYG000001174_00433;MGYG000000074_00883;MGYG000003423_01365;MGYG000004748_00450;MGYG000002944_01470;MGYG000001345_01069;MGYG000002438_00285;MGYG000002026_00895;MGYG000004464_00783;MGYG000002926_01713;MGYG000004513_03104;MGYG000000254_01186;MGYG000002478_03999;MGYG000004760_00889;MGYG000001313_02393;MGYG000004847_00969;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000002067_00330;MGYG000002281_04045;MGYG000000043_01774;MGYG000004658_00366;MGYG000002084_00526;MGYG000004822_01148;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000004526_01607;MGYG000002455_02200;MGYG000001356_02656;MGYG000004487_00117;MGYG000001608_00559;MGYG000001489_03093;MGYG000004726_03349;MGYG000004638_00838;MGYG000000445_00706;MGYG000001302.1_00095;MGYG000003252_01337;MGYG000002095_00148;MGYG000003202_00946;MGYG000003514_00715;MGYG000003681_00790;MGYG000002933_02039;MGYG000004482_00387;MGYG000000196_00479;MGYG000004285_00359;MGYG000003693_00860;MGYG000001657_02260;MGYG000001661_02632;MGYG000004642_01190;MGYG000002549_00455;MGYG000002737_00455;MGYG000003155_00741;MGYG000000170_00182;MGYG000003908_00471;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.3968253968253968 976|Bacteroidetes 0.6507936507936508 G 0.5079365079365079 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7777777777777778 gap 0.9365079365079365 - 0.9206349206349206 1.2.1.12 0.9841269841269841 ko:K00134 0.9841269841269841 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9841269841269841 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9841269841269841 R01061 0.9841269841269841 RC00149 0.9841269841269841 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9841269841269841 - 1.0 - 1.0 - 0.9523809523809523 Gp_dh_C,Gp_dh_N 0.9841269841269841 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.015873015873015872 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9841269841269841 0.9841269841269841 0.9841269841269841 0.9841269841269841 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9841269841269841 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9841269841269841 none 1.0 0 0 197619 0 0 0 0 0 156396 0 0 0 0 0 0 0 219527 0 0 217884 0 123513 0 233947 0 0 0 0 0 527442 0 0 0 171195 0 147456 0 233561 0 0 472325 0 0 526115 0 0 463242 0 0 0 0 0 0 0 0 855429 0 373681 0 279120 0 631121 0 0 0 632946 0 0 0 0 291739 772569 0 0 0 1510992 0 0 616012 0 0 423081 0 0 1311142 0 0 248033 0 0 0 0 2600468 1409353 0 288603 332386 452286 3528830 1698650 0 0 0 1536743 0 197984 0 0 0 568287 0 1915731 0 2130831 0 0 404442 0 0 0 0 0 0 0 0 470117 0 0 0 0 0 0 0 159376 0 200241 0 1097272 0 0 0 0 0 475551 0 0 582162 1603846 0 371224 0 189437 0 0 1149676 0 0 1198027 0 0 1625946 0 0 1067212 0 0 0 0 1419281 3485394 0 1371219 1159462 0 2466920 1282929 0 0 0 490272 0 1656917 0 0 439824 634678 0 756984 0 389461 +(Unknown_216)TTLTAAITK MGYG000000080_02058;MGYG000000171_02844;MGYG000004732_02398;MGYG000000303_01575;MGYG000000089_01901;MGYG000001688_04229;MGYG000004718_00646;MGYG000003547_00975;MGYG000000280_01200;MGYG000002259_00929;MGYG000001754_00089;MGYG000004565_01266;MGYG000000198_01165;MGYG000003324_00542;MGYG000003155_00314;MGYG000004804_01395;MGYG000002563_00522;MGYG000003937_01027;MGYG000003411_00716;MGYG000000919_01815;MGYG000001234_01151;MGYG000003992_01709;MGYG000001623_00993;MGYG000002563_00509;MGYG000003895_00135;MGYG000001619_01314;MGYG000000348_00283;MGYG000004296_01668;MGYG000004508_00787;MGYG000000742_00548;MGYG000001809_00576;MGYG000004573_00004;MGYG000001434_01407;MGYG000000258_00266;MGYG000001541_00185;MGYG000001300_00280;MGYG000003851_00676;MGYG000004769_00437;MGYG000002084_01252;MGYG000003869_01538;MGYG000002578_00911;MGYG000001611_00087;MGYG000000371_01541;MGYG000000255_02009;MGYG000002040_01212;MGYG000000404_00531;MGYG000000164_01096;MGYG000000018_00453;MGYG000002794_01318;MGYG000001606_01669;MGYG000004474_01617;MGYG000004804_00945;MGYG000003868_01133;MGYG000001359_01254;MGYG000002224_01123;MGYG000004201_01254;MGYG000000532_02409;MGYG000000036_01380;MGYG000001248_01383;MGYG000002286_02469;MGYG000003073_01160;MGYG000001616_00520;MGYG000002937_00892;MGYG000002052_00232;MGYG000000369_00927;MGYG000001086_01249;MGYG000001365_00649;MGYG000001615_01716;MGYG000002116_00788;MGYG000002854_00111;MGYG000002695_01057;MGYG000000016_02519;MGYG000001756_00183;MGYG000003819_01356;MGYG000004769_00412;MGYG000000395_01440;MGYG000001524_01606;MGYG000000802_00776;MGYG000000271_03365;MGYG000000867_00556;MGYG000002944_02285;MGYG000002993_01302;MGYG000001310_01963;MGYG000002953_03321;MGYG000000022_02283;MGYG000002528_01098;MGYG000004680_02443;MGYG000000090_01714;MGYG000001737_01514;MGYG000002895_00716;MGYG000003428_00555;MGYG000001248_00621;MGYG000003686_02367;MGYG000001784_02227;MGYG000001749_02490;MGYG000002980_01277;MGYG000001779_00600;MGYG000001356_01661;MGYG000004526_00639;MGYG000003166_01350;MGYG000003868_01166;MGYG000003425_03741;MGYG000000251_00064;MGYG000001590_00854;MGYG000000233_00807;MGYG000000142_00171;MGYG000002702_01978;MGYG000001528_00736;MGYG000000182_00585;MGYG000002143_01659;MGYG000000084_02000;MGYG000002126_00299;MGYG000004642_00846;MGYG000001559_00042;MGYG000000187_02029;MGYG000002854_00124;MGYG000001698_04050;MGYG000001443_06656;MGYG000000445_01370;MGYG000002272_01482;MGYG000000249_00026;MGYG000001444_01618;MGYG000002212_00196;MGYG000004799_01385;MGYG000001814_01592;MGYG000003656_01823;MGYG000003486_01055;MGYG000002970_01555;MGYG000003013_00349;MGYG000003484_00308;MGYG000002715_01695;MGYG000002659_00459;MGYG000001732_00030;MGYG000000206_00901;MGYG000004733_01211;MGYG000001389_01588;MGYG000003096_01037;MGYG000002106_00224;MGYG000001673_01975;MGYG000001654_02237;MGYG000002619_00483;MGYG000004735_00884;MGYG000002926_00232;MGYG000002578_00898;MGYG000001760_00949;MGYG000000099_01234;MGYG000000392_00966;MGYG000000133_02991;MGYG000004879_01608;MGYG000001389_00024;MGYG000002707_01740;MGYG000000466_00679;MGYG000001444_01634;MGYG000002994_01317;MGYG000002202_00030;MGYG000003266_00392;MGYG000004482_01535;MGYG000001576_02230;MGYG000000216_02406;MGYG000003628_01000;MGYG000001563_01273;MGYG000000034_01346;MGYG000002685_01157;MGYG000001652_01300;MGYG000002557_00102;MGYG000001338_03373;MGYG000004502_00031;MGYG000000139_00697;MGYG000002762_01733;MGYG000001502_01278;MGYG000003266_00955;MGYG000004826_01022;MGYG000003274_01474;MGYG000001757_01274;MGYG000002234_01026;MGYG000000032_01232;MGYG000001777_01732;MGYG000002105_00002;MGYG000004285_00597;MGYG000000333_00136;MGYG000000262_00030;MGYG000004196_01067;MGYG000002772_01895;MGYG000002057_01066;MGYG000003921_01124;MGYG000001238_02207;MGYG000002996_00986;MGYG000002448_02351;MGYG000004475_00887;MGYG000001319_01764;MGYG000002279_01932;MGYG000000201_03875;MGYG000004547_01366;MGYG000003063_00662;MGYG000001516_01186;MGYG000004717_00227;MGYG000004726_01622;MGYG000004276_00122;MGYG000001925_01419;MGYG000004788_02115;MGYG000001315_01207;MGYG000001602_02247;MGYG000000266_00259;MGYG000003273_00234;MGYG000000140_01590;MGYG000001065_02730;MGYG000002609_01147;MGYG000000263_00836;MGYG000003899_01642;MGYG000003583_01411;MGYG000000179_00920;MGYG000000173_00405;MGYG000000177_01044;MGYG000002290_01325;MGYG000001531_00906;MGYG000003465_01528;MGYG000001141_02439;MGYG000002530_01393;MGYG000000024_03409;MGYG000003872_01017;MGYG000002972_00178;MGYG000001567_01738;MGYG000001439_02427;MGYG000004087_00551;MGYG000000242_00282;MGYG000002417_01244;MGYG000001559_01093;MGYG000002641_00069;MGYG000004558_00415;MGYG000000212_03313;MGYG000002830_01189;MGYG000002837_02416;MGYG000001500_01929;MGYG000000370_00784;MGYG000002006_00835;MGYG000000193_02083;MGYG000000622_01283;MGYG000002720_00092;MGYG000003236_02455;MGYG000004746_00230;MGYG000004630_01824;MGYG000000501_01307;MGYG000000405_00711;MGYG000002848_00884;MGYG000001617_01406;MGYG000003001_00359;MGYG000002596_02296;MGYG000003620_01283;MGYG000001007_01315 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 0.20080321285140562 186801|Clostridia 0.7469879518072289 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.9678714859437751 - 1.0 ko:K02358 0.9919678714859438 - 0.9919678714859438 - 0.9919678714859438 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9919678714859438 - 0.9919678714859438 - 1.0 - 0.9959839357429718 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_02058 0.004016064257028112 - - - - 1.0 1.0 1.0 1.0 - 0.9919678714859438 K02358:tuf, TUFM; elongation factor Tu 0.9919678714859438 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 616757 0 0 0 1498697 0 0 0 1070641 0 0 1022783 0 0 1633232 0 0 0 0 0 0 289005 0 0 0 0 2386742 0 1510092 0 2111448 3711546 702591 0 0 0 2716175 0 1004187 2775147 1665908 3514938 2707232 0 0 0 2431247 0 0 1085011 0 0 1010706 0 0 0 0 0 0 2393428 0 0 0 0 1209597 0 2180595 0 2034599 0 1592070 0 0 0 375624 0 2463110 2716646 1926600 907988 1895151 0 0 0 874951 0 0 1650826 0 0 639372 0 0 0 0 0 0 0 0 0 0 0 1452880 0 0 0 0 1540415 666581 0 0 0 0 0 406121 653903 0 2723515 0 0 0 0 0 +(Unknown_216)VLILTGGPDKK MGYG000002492_00917;MGYG000000280_01601 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.5 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.5 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1272897 0 0 0 0 1314779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)VLPELNGK MGYG000000038_02185;MGYG000001311_02933;MGYG000000375_01483;MGYG000003582_01256;MGYG000001558_01857;MGYG000002619_02023;MGYG000003374_01118;MGYG000003821_01266;MGYG000000272_02321;MGYG000002947_01132;MGYG000001400_02195;MGYG000003828_01578;MGYG000000354_00611;MGYG000004681_01193;MGYG000000262_01195;MGYG000001763_00396;MGYG000001707_00061;MGYG000003110_00098;MGYG000000223_00996;MGYG000001711_02099;MGYG000002258_00386;MGYG000004732_01055;MGYG000001255_00370;MGYG000001496_01122;MGYG000004493_00097;MGYG000000002_02120;MGYG000002194_02222;MGYG000004271_00554;MGYG000002966_00075;MGYG000003274_01603;MGYG000002970_00369;MGYG000004317_00142;MGYG000000233_00345;MGYG000001652_01009;MGYG000000231_00608;MGYG000000077_00219;MGYG000000127_04855;MGYG000002993_00787;MGYG000000815_03106;MGYG000001445_01532;MGYG000002945_00682;MGYG000000229_00395;MGYG000004610_00503;MGYG000002098_00013;MGYG000001608_00559;MGYG000002212_00259;MGYG000004826_01307;MGYG000001606_02632;MGYG000000173_00071;MGYG000000213_00374;MGYG000003465_00706;MGYG000002517_01026;MGYG000000003_00712;MGYG000004707_01697;MGYG000002683_02093;MGYG000000212_01474;MGYG000001643_00773;MGYG000002126_00535;MGYG000004642_01190;MGYG000001789_00244;MGYG000000515_01608;MGYG000001338_02547;MGYG000003074_01265;MGYG000001493_05257;MGYG000004396_00612;MGYG000000217_00275;MGYG000002905_02083;MGYG000001439_00571;MGYG000003589_01892;MGYG000000280_02459;MGYG000000188_00829;MGYG000000249_01352;MGYG000003695_01114;MGYG000003423_01365;MGYG000004756_01346;MGYG000004691_00618;MGYG000002641_00563;MGYG000000193_03247;MGYG000000140_01181;MGYG000000080_03115;MGYG000001562_00044;MGYG000002279_00557;MGYG000004799_00704;MGYG000001814_01253;MGYG000002968_00328;MGYG000003656_01296;MGYG000003372_00674;MGYG000000242_02076;MGYG000002492_01379;MGYG000000198_04065;MGYG000001199_01005;MGYG000001749_01249;MGYG000001658_00407;MGYG000001688_03910;MGYG000002972_00451;MGYG000000278_03657;MGYG000000362_01155;MGYG000001319_00348;MGYG000000495_01130;MGYG000001303_01883;MGYG000000258_00590;MGYG000004638_00838;MGYG000002051_00298;MGYG000000187_02264;MGYG000003504_01686;MGYG000000371_00136;MGYG000004519_00423;MGYG000003202_00946;MGYG000000615_00488;MGYG000001423_00991;MGYG000001157_00577;MGYG000000584_01909;MGYG000000171_00850;MGYG000000195_01135;MGYG000001008_00728;MGYG000000271_03250;MGYG000002293_01263;MGYG000000562_01218;MGYG000004622_00259;MGYG000000022_00437;MGYG000000133_02283;MGYG000002298_02410;MGYG000002675_01717;MGYG000000489_00503;MGYG000000399_00360;MGYG000003694_01737;MGYG000002540_02142;MGYG000003831_00170;MGYG000001607_01815;MGYG000000230_01325;MGYG000000484_01691;MGYG000003697_01698;MGYG000002057_00658;MGYG000001710_00672;MGYG000000036_01872;MGYG000003001_00320;MGYG000000205_02269;MGYG000003510_00403;MGYG000000802_01543;MGYG000000690_01295;MGYG000002528_00367;MGYG000004140_01100;MGYG000002478_03999;MGYG000002286_00420;MGYG000000164_00800;MGYG000004847_00969;MGYG000001748_01525;MGYG000002946_02881;MGYG000000150_00838;MGYG000000243_01331;MGYG000002506_01169;MGYG000000404_00344;MGYG000004815_01345;MGYG000001718_00619;MGYG000000141_02825;MGYG000003552_01242;MGYG000003702_00925;MGYG000001781_01334;MGYG000000392_01140;MGYG000002304_00547;MGYG000001356_02656;MGYG000001546_00360;MGYG000002494_01669;MGYG000000045_02136;MGYG000002507_01945;MGYG000000162_00065;MGYG000000089_01653;MGYG000004296_01958;MGYG000002155_00766;MGYG000000179_02084;MGYG000000142_01979;MGYG000000263_01341;MGYG000000806_01930;MGYG000001697_00003;MGYG000001299_00204;MGYG000000251_00555;MGYG000002992_00164;MGYG000002974_01418;MGYG000004285_00359;MGYG000002997_01277;MGYG000003819_01468;MGYG000002025_02240;MGYG000000463_00862;MGYG000002737_00455;MGYG000000433_00630;MGYG000001602_01805;MGYG000004884_01637;MGYG000002052_00078;MGYG000000053_01377;MGYG000001970_02077;MGYG000004246_01300;MGYG000000153_00303;MGYG000003908_00471;MGYG000001315_01699;MGYG000001627_00130;MGYG000002035_01208;MGYG000000941_01985;MGYG000003409_01628;MGYG000003012_02911;MGYG000001310_02090;MGYG000002445_01920;MGYG000000325_00586;MGYG000002834_00628;MGYG000000909_00644;MGYG000002944_01470;MGYG000002775_01122;MGYG000003431_01105;MGYG000003149_01253;MGYG000002026_00895;MGYG000000369_00836;MGYG000003450_00202;MGYG000001954_02254;MGYG000000254_01186;MGYG000002638_00362;MGYG000001415_02219;MGYG000000215_01375;MGYG000001065_01088;MGYG000004810_01402;MGYG000000100_02166;MGYG000002131_02428;MGYG000002067_00330;MGYG000003335_00316;MGYG000000084_01085;MGYG000000836_00852;MGYG000001300_02008;MGYG000004866_01631;MGYG000003937_01177;MGYG000000252_01324;MGYG000000365_00999;MGYG000003363_01174;MGYG000004822_01148;MGYG000000301_01012;MGYG000004722_00591;MGYG000000044_01948;MGYG000001186_01925;MGYG000004087_02290;MGYG000003899_01412;MGYG000000312_01508;MGYG000000204_00778;MGYG000003013_01053;MGYG000002857_01020;MGYG000004288_00401;MGYG000000974_00886;MGYG000004714_00143;MGYG000000281_02732;MGYG000002556_00846;MGYG000001619_01736;MGYG000000398_00286;MGYG000001683_01827;MGYG000001421_02311;MGYG000004789_01485;MGYG000003812_01036;MGYG000004735_01946;MGYG000003503_01071;MGYG000000673_01725;MGYG000000266_00946;MGYG000001567_00998;MGYG000004593_01977;MGYG000000345_01945 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.1583011583011583 186801|Clostridia 0.6718146718146718 C 0.5675675675675675 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5868725868725869 gap 0.9768339768339769 - 0.9305019305019305 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9652509652509652 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_02185 0.003861003861003861 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 668170 0 842327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 947340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)VLVATDKPFAK MGYG000004763_00834;MGYG000000224_02581;MGYG000000243_00366;MGYG000003681_00721;MGYG000002561_02267;MGYG000003367_00322;MGYG000003363_03157;MGYG000002478_03726;MGYG000001346_03050 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 0.8888888888888888 976|Bacteroidetes 1.0 C 0.8888888888888888 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004763_00834 0.1111111111111111 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385764 0 0 0 0 213189 0 0 599399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_216)YAWEEAEHASK MGYG000000170_00133;MGYG000001302.1_00876;MGYG000002007_00952;MGYG000000196_00855;MGYG000002561_03555;MGYG000001461_01112;MGYG000002455_02720;MGYG000001337_03530;MGYG000002203_01956;MGYG000002867_00443;MGYG000004006_00639;MGYG000003467_00199;MGYG000000437_02174;MGYG000000074_02407;MGYG000001546_02758;MGYG000000243_02810;MGYG000000236_00566;MGYG000000003_01138;MGYG000002171_00343;MGYG000001420_01351;MGYG000001920_02116 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1592@1|root,COG1592@2|Bacteria,4NJ7V@976|Bacteroidetes,2FP1G@200643|Bacteroidia,22UC5@171550|Rikenellaceae 0.5714285714285714 976|Bacteroidetes 1.0 C 1.0 Rubrerythrin 0.5714285714285714 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000170_00133 0.047619047619047616 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 104326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609879 0 0 0 0 404681 0 0 76782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105267 0 0 0 0 214565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_234)QTKLTTKESELLGLLC(Carbamidomethyl)AHANEILQR MGYG000002478_00018 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia,4AKWQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 1.0 rprY 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Response_reg,Trans_reg_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00018 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 46570205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_248)VCGYDDYSLFLINSGAEANENALK MGYG000003363_01506 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900766195|m__MGYG000003363 1.0 COG4992@1|root,COG4992@2|Bacteria,4NE0Z@976|Bacteroidetes,2FNR5@200643|Bacteroidia,4AKEG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family 1.0 argD 1.0 - 1.0 2.6.1.11,2.6.1.17 1.0 ko:K00821 1.0 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00028,M00845 1.0 R02283,R04475 1.0 RC00006,RC00062 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003363_01506 1.0 acetylornithine transaminase. | succinyldiaminopimelate transaminase. succinylornithine aminotransferase. | succinyldiaminopimelate transferase. Also acts on L-ornithine and N(2)-succinyl-L-ornithine. 2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L- glutamate 5-semialdehyde. | 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (S)-2- succinylamino-6-oxoheptanedioate + L-glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00821:argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1303165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_250)PILGGEATFSFGEAIK MGYG000001338_01563 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 2BJ52@1|root,32DE8@2|Bacteria,1UQYJ@1239|Firmicutes,258RQ@186801|Clostridia,3WMD6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Protein of unknown function (DUF2829) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF2829 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01563 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3457102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_302)EELTGPEYARRFINQALDLNIEYR MGYG000002517_00256 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00256 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1186787 0 0 0 0 0 0 0 +(Unknown_302)EGGRTVGAGQIIEIIK MGYG000000170_00073 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900240235|m__MGYG000000170 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22UC0@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000170_00073 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_420)EAADKATADDIK MGYG000002517_00194;MGYG000000271_03294 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00194 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1525049 0 0 0 0 0 0 0 0 0 3086730 0 0 0 0 3430263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2307655 0 0 0 0 0 0 0 0 0 4133612 0 0 0 0 1068862 0 0 0 +(Unknown_420)EEINAAMK MGYG000004828_01576;MGYG000002485_02480 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004828_01576 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 274113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1475699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1731484 0 0 +(Unknown_420)EGATAIC(Carbamidomethyl)HGATGK MGYG000003012_02122;MGYG000001311_02316;MGYG000002945_01110;MGYG000000076_00148;MGYG000000271_00682;MGYG000000181_00360;MGYG000004869_02793;MGYG000000177_02080;MGYG000004296_00572;MGYG000003702_01632;MGYG000000245_01511;MGYG000000179_03143;MGYG000004087_00138;MGYG000004642_01769;MGYG000002517_01103;MGYG000000404_01916;MGYG000001374_00302;MGYG000000198_02164 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,21XSH@1506553|Lachnoclostridium 0.2777777777777778 186801|Clostridia 1.0 E 0.7222222222222222 Belongs to the argininosuccinate synthase family. Type 1 subfamily 0.6666666666666666 argG 1.0 - 1.0 6.3.4.5 1.0 ko:K01940 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 1.0 M00029,M00844,M00845 1.0 R01954 1.0 RC00380,RC00629 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Arginosuc_synth 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003012_02122 0.05555555555555555 argininosuccinate synthase. citrulline--aspartate ligase. - ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids|Fluid shear stress and atherosclerosis 1.0 K01940:argG, ASS1; argininosuccinate synthase [EC:6.3.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179852 0 0 0 0 0 0 0 0 0 448160 274145 0 1126431 0 538502 0 0 898951 0 0 0 1661016 1913329 1082593 0 0 1716584 810628 1402206 0 0 0 0 0 0 1607396 0 565081 2193899 0 0 0 0 0 1004996 0 0 1869853 1922863 1965263 +(Unknown_420)GQVLAKPGTVTC(Carbamidomethyl)HHK MGYG000002492_00344;MGYG000002517_00205 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00344 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697547 0 0 0 0 333997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 688586 0 0 0 0 0 0 0 0 2026660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1043749 0 990302 0 0 1784433 0 1484797 +(Unknown_420)IYSESADETKDK MGYG000000179_05046 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_05046 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4369750 0 733366 0 0 1574352 0 0 1585972 0 2231910 2457369 0 3895145 0 0 6837971 0 0 7107469 2334570 0 0 3973216 3072892 3721635 6588020 0 0 4470065 0 0 2549585 0 0 6066133 6779381 4506243 +(Unknown_420)KATQVYSHEVEK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 0.5 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_420)KVVLTANAQK MGYG000000031_02020;MGYG000000002_02249;MGYG000000142_00761;MGYG000000142_02498;MGYG000001698_00102;MGYG000001338_00681 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae 0.8333333333333334 186801|Clostridia 1.0 H 1.0 Belongs to the formate--tetrahydrofolate ligase family 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_02020 0.16666666666666666 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01938:fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1127960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_420)KYVQDTSVTSK MGYG000000089_02197 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000089_02197 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4141698 0 0 0 0 534175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_420)MTAAKAEQLIDQGIITDGMIVK MGYG000002494_01894 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,3XM7I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde 1.0 argC 1.0 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.2.1.38 1.0 ko:K00145 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028,M00845 1.0 R03443 1.0 RC00684 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iSSON_1240.SSON_4131 1.0 AA_kinase,Semialdhyde_dh,Semialdhyde_dhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01894 1.0 N-acetyl-gamma-glutamyl-phosphate reductase. NAGSA dehydrogenase. - N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00145:argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] 1.0 none 1.0 0 302455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_420)PEIMLVGATAIGR MGYG000000312_02427;MGYG000000164_00688;MGYG000002492_00661;MGYG000002517_00544;MGYG000000245_02023;MGYG000002528_02669 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8333333333333334 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000312_02427 0.16666666666666666 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_420)TDGSHVTSDLGDGKK MGYG000000089_02197 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000089_02197 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2718652 0 0 0 0 3175332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Unknown_420)VSQAEADDIKK MGYG000002610_00935;MGYG000002619_00763;MGYG000002651_00254;MGYG000001300_02635;MGYG000002223_01729 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002610_00935 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 803889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Xlink_BS2G[113])SKVVLAGAC(Carbamidomethyl)R MGYG000002857_02065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Hydrogeniiclostridium|s__Hydrogeniiclostridium sp900550095|m__MGYG000002857 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,27J2B@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002857_02065 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 989666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(Xlink_EGS[226])AVTQALGMIETK MGYG000000359_01134;MGYG000000359_01133 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7182|s__|m__MGYG000000359 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia 1.0 186801|Clostridia 1.0 CQ 1.0 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000359_01134 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259914 0 0 0 0 0 0 0 0 0 0 0 0 268090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306932 0 0 0 0 0 0 0 0 0 0 525073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 761700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1577690 0 0 0 0 0 0 0 0 0 0 2126085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(biotinAcrolein298)MESVMK MGYG000002438_02119 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG2133@1|root,COG2133@2|Bacteria,4PMXZ@976|Bacteroidetes,2G0K9@200643|Bacteroidia,2324V@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Domain of Unknown Function (DUF1080) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1080 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02119 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314196 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134411 0 0 0 0 0 0 0 0 0 0 6840683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15171939 0 0 0 0 0 0 0 0 0 0 0 0 +(dNIC)ADIIMILINDEK MGYG000000301_00839;MGYG000004735_00452;MGYG000000201_04066;MGYG000004087_02660;MGYG000001496_01234;MGYG000000271_00298;MGYG000002517_01587 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 0.42857142857142855 186801|Clostridia 1.0 EH 0.5714285714285714 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_00839 0.14285714285714285 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(dNIC)AEILKEEGYIANYK MGYG000004828_02462;MGYG000002485_02425 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0096@1|root,COG0096@2|Bacteria,379ZT@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit 1.0 rpsH 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02994 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004828_02462 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02994:RP-S8, MRPS8, rpsH; small subunit ribosomal protein S8 1.0 none 1.0 0 0 402398 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225817 0 0 0 0 0 0 0 567546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463947 0 0 0 0 408322 0 0 162409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221515 0 0 0 0 140596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524752 +(dNIC)FAPHMALVPMVIEQTSR MGYG000002535_03209;MGYG000002494_00469 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0740@1|root,COG0740@2|Bacteria,1MV46@1224|Proteobacteria,1RNR6@1236|Gammaproteobacteria,3WVQ6@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 OU 1.0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins 1.0 clpP 1.0 GO:0000502,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009314,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017171,GO:0019538,GO:0019899,GO:0030163,GO:0031597,GO:0032991,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051117,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 1.0 3.4.21.92 1.0 ko:K01358 1.0 ko04112,ko04212,map04112,map04212 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 CLP_protease 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002535_03209 0.5 endopeptidase Clp. protease Ti. Belongs to peptidase family S14. Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs). 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter|Longevity regulating pathway - worm 1.0 K01358:clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] 1.0 none 1.0 0 0 0 0 0 474412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282249 0 415205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1062663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1340656 0 743555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338040 0 260946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(dNIC)INDLCPVDYMAYMLK MGYG000002293_01263;MGYG000003697_01698 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01263 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7468347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(dNIC)QLDEAQAGDNIGALLR MGYG000002492_00344;MGYG000002517_00205;MGYG000000245_03248;MGYG000002670_00364 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00344 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)AAASESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004884_01637 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)ACKVPFQPR MGYG000000039_01677;MGYG000003291_01619;MGYG000002040_00964;MGYG000002272_00439;MGYG000002545_01146;MGYG000002059_01092;MGYG000001157_01746;MGYG000003899_00602;MGYG000000084_00993;MGYG000003166_00747;MGYG000002274_00854;MGYG000001255_02057;MGYG000001300_02903 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Probable zinc-ribbon domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-trcl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000039_01677 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2724752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4645587 0 0 0 0 0 0 0 0 +(glycidamide)ADDEANTITVDGK MGYG000000690_01295;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.5 186801|Clostridia 1.0 G 0.5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000690_01295 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)AKMPCLVTALSELNQPR MGYG000000997_00555;MGYG000000271_02101 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_00555 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)ALAATDGDMDKAVEFLR MGYG000001619_02441;MGYG000000233_01317;MGYG000000179_02938;MGYG000000909_00278;MGYG000000274_02582;MGYG000000198_02721;MGYG000000194_00522;MGYG000000278_03744;MGYG000002445_00993 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,21ZJJ@1506553|Lachnoclostridium 0.8888888888888888 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001619_02441 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1470524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1591922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)ALLLLK MGYG000001328_01553;MGYG000004536_01045;MGYG000000312_00604;MGYG000002234_01825;MGYG000000205_01544;MGYG000003142_01539;MGYG000000389_00676;MGYG000002517_01844;MGYG000001489_04239;MGYG000000245_00420;MGYG000001423_01504 domain d__Bacteria 1.0 COG1143@1|root,COG4624@1|root,COG1143@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia 0.2727272727272727 186801|Clostridia 0.8181818181818182 C 0.5454545454545454 Iron only hydrogenase large subunit, C-terminal domain 0.2727272727272727 - 0.7272727272727273 - 1.0 1.12.7.2 0.5454545454545454 ko:K00533 0.5454545454545454 - 0.7272727272727273 - 0.7272727272727273 R00019 0.5454545454545454 - 0.7272727272727273 ko00000,ko01000 0.5454545454545454 - 1.0 - 1.0 - 1.0 Fe_hyd_lg_C,Fer4,Fer4_6,Fer4_7 0.5454545454545454 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001328_01553 0.09090909090909091 ferredoxin hydrogenase. uptake hydrogenase. Can use molecular hydrogen for the reduction of a variety of substances.-!-Formerly EC 1.12.1.1, EC 1.12.7.1, EC 1.18.3.1, EC 1.18.99.1 and EC 1.98.1.1. H2 + 2 oxidized [2Fe-2S]-[ferredoxin] = 2 H(+) + 2 reduced [2Fe-2S]- [ferredoxin]. 0.5454545454545454 0.5454545454545454 0.5454545454545454 0.5454545454545454 - 0.7272727272727273 K00533:E1.12.7.2L; ferredoxin hydrogenase large subunit [EC:1.12.7.2] 0.5454545454545454 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3165772 0 0 3676994 0 0 0 0 0 3724852 0 0 1425838 0 0 0 0 0 2921146 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)APGDDATYLDYFQK MGYG000002993_01407 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-170|s__CAG-170 sp000432135|m__MGYG000002993 1.0 COG0747@1|root,COG0747@2|Bacteria 1.0 2|Bacteria 1.0 E 1.0 dipeptide transport 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002993_01407 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1079473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)APKPVFTDAYFLDK MGYG000004536_01290 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900542505|m__MGYG000004536 1.0 COG0511@1|root,COG5016@1|root,COG0511@2|Bacteria,COG5016@2|Bacteria,4PKTH@976|Bacteroidetes,2G35Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Conserved carboxylase domain 1.0 - 1.0 - 1.0 4.1.1.3,6.4.1.1 1.0 ko:K01571,ko:K01960 1.0 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 1.0 M00173,M00620 1.0 R00217,R00344 1.0 RC00040,RC00367 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 Biotin_lipoyl,Biotin_lipoyl_2,HMGL-like,OAD_gamma,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004536_01290 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | pyruvate carboxylase. | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). pyruvic carboxylase. | oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The animal enzyme requires acetyl-CoA. | The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. ATP + hydrogencarbonate + pyruvate = ADP + H(+) + oxaloacetate + phosphate. | H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]|K01960:pycB; pyruvate carboxylase subunit B [EC:6.4.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)DIYENLHAAGVVDPAK MGYG000001345_00379 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides xylanisolvens|m__MGYG000001345 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000001345_00379 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 969220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1116479 0 1003398 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3977843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2315485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1763573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)DRPVYC(Carbamidomethyl)SEC(Carbamidomethyl)FAK MGYG000000084_00993;MGYG000003937_01603 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG1278@1|root,COG1278@2|Bacteria,1VBBH@1239|Firmicutes,24QK9@186801|Clostridia,3WK5C@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Probable zinc-ribbon domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-trcl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000084_00993 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1072046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1205007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1366227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1152540 +(glycidamide)FDNYTFDGSIK MGYG000003279_01059 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900541585|m__MGYG000003279 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003279_01059 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1236422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)GENITDLAAK MGYG000000022_01830 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000022_01830 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44796621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)GILLGYAR MGYG000002517_01919 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,25CDF@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 M42 glutamyl aminopeptidase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Peptidase_M42 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01919 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73687389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)GLCGTDANNLLTSVVER MGYG000001346_03676;MGYG000002281_00884;MGYG000002561_01098;MGYG000002455_04522 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1208@1|root,COG1208@2|Bacteria,4PKJR@976|Bacteroidetes,2G07F@200643|Bacteroidia,4AKG8@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 JM 1.0 COG NOG09722 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NTP_transf_3,NTP_transferase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_03676 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1016449 0 0 0 0 0 1159941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)GNAGAPAVHYLLDSR MGYG000000074_00948 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0526@1|root,COG0526@2|Bacteria,4NEX3@976|Bacteroidetes,2FN8N@200643|Bacteroidia,22UCK@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 CO 1.0 Domain of unknown function (DUF4369) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AhpC-TSA,DUF4369,Thioredoxin_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00948 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 67666 0 232232 0 0 161008 0 91998 0 0 0 85927 0 0 0 0 849628 1481105 0 0 0 129337 0 0 0 0 0 0 0 0 88365 0 0 0 0 170450 0 0 190099 0 243118 75866 0 0 0 0 0 0 0 166120 0 0 115293 0 0 0 0 0 0 0 0 0 0 0 0 132961 0 0 0 0 0 0 0 0 0 0 0 0 113341 0 0 0 0 0 0 0 0 0 0 200675 0 0 0 110462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217433 0 199730 243403 0 305923 0 261951 0 0 0 0 189109 122065 131847 0 209645 261718 552513 405226 0 709563 0 0 0 0 0 0 0 166788 227152 0 0 0 0 428744 0 0 2231405 0 3992888 3502307 0 2807449 0 3247484 0 0 0 2200818 2702016 2910195 3783665 0 5345900 6694484 2336939 2646082 0 4181194 0 0 0 0 3227904 4474240 0 2358576 1787775 0 0 0 0 2529452 +(glycidamide)HFGPTYYAFDMGR MGYG000000074_00680 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1409@1|root,COG1409@2|Bacteria,4NF9K@976|Bacteroidetes,2FPK8@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 C terminal of Calcineurin-like phosphoesterase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Metallophos,MetallophosC,MetallophosN,PQQ_2,PQQ_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00680 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 74796 0 0 0 0 0 77168 0 101923 0 0 0 0 0 0 0 0 0 0 0 0 0 115557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79656 0 0 0 0 0 0 0 72127 0 0 0 0 0 88258 104813 0 0 0 0 0 0 0 0 0 85634 71387 0 90115 83691 0 0 0 0 0 0 68917 0 1476840 0 946451 0 1396508 1143513 0 1245734 1392259 1190858 0 0 0 946820 1224003 1014618 1334829 0 1741689 0 0 1174221 0 1144432 0 1613522 1170807 0 1465981 2068138 0 0 719333 0 0 0 1419250 1009273 +(glycidamide)IDEYFGLETLK MGYG000000036_01966;MGYG000000142_00583;MGYG000000212_00914;MGYG000000216_00022;MGYG000000038_02280;MGYG000000171_01362;MGYG000002279_00145 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 1.0 rpsI 1.0 - 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000036_01966 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02996:RP-S9, MRPS9, rpsI; small subunit ribosomal protein S9 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 868773 0 0 141462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)IGGGMGC(Carbamidomethyl)STIVERD MGYG000000262_02231;MGYG000000077_02464;MGYG000002517_00540 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 0.6666666666666666 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02231 0.3333333333333333 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 957487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)IIAGNIIVR MGYG000002293_01155;MGYG000001770_01237;MGYG000001447_00270;MGYG000003697_02055 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0211@1|root,COG0211@2|Bacteria,4NS7T@976|Bacteroidetes,2FTXU@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL27 family 1.0 rpmA 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02899 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Ribosomal_L27 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01155 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02899:RP-L27, MRPL27, rpmA; large subunit ribosomal protein L27 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1653863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)IIIAAHGNSLR MGYG000002494_00767;MGYG000001613_00806 domain d__Bacteria 1.0 COG0588@1|root,COG0588@2|Bacteria,1MUVE@1224|Proteobacteria,1RNCX@1236|Gammaproteobacteria 0.5 1236|Gammaproteobacteria 0.5 G 1.0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily 0.5 gpmA 1.0 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 0.5 5.4.2.11 0.5 ko:K01834 0.5 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 0.5 M00001,M00002,M00003 0.5 R01518 0.5 RC00536 0.5 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.5 - 1.0 - 1.0 - 1.0 His_Phos_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00767 0.5 phosphoglycerate mutase (2,3-diphosphoglycerate-dependent). phosphoglyceromutase. The enzymes from vertebrates, platyhelminths, mollusks, annelids, crustaceans, insects, algae, some fungi, yeast and some bacteria (particularly Gram-negative) require 2,3-bisphospho-D-glycerate as a cofactor.-!-The enzyme is activated by 2,3-bisphospho-D-glycerate by transferring a phosphate to histidine (His(10) in man and Escherichia coli, His(8) in Saccharomyces cerevisiae).-!-This phosphate can be transferred to the free OH of 2-phospho-D- glycerate, followed by transfer of the phosphate already on the phosphoglycerate back to the histidine. cf. EC 5.4.2.12.-!-The enzyme has no requirement for metal ions.-!-This enzyme also catalyze, slowly, the reactions of EC 5.4.2.4.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 0.5 0.5 0.5 0.5 Glycolysis / Gluconeogenesis|Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|Glucagon signaling pathway|Central carbon metabolism in cancer 0.5 K01834:PGAM, gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1719567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)IPEYQYQISK MGYG000002517_00722 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00722 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 416962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287061 0 0 0 0 0 0 317870 0 0 429172 433415 0 0 0 0 0 0 0 0 396957 0 409326 0 0 0 0 0 272625 293740 383180 0 0 706256 0 0 0 422608 503463 490222 438957 0 4664027 0 0 5781183 0 0 2541281 5840523 5548346 0 0 2723194 0 0 0 2509041 4752302 0 4935116 0 0 0 0 0 5957128 4988744 5611902 0 0 4632889 0 0 0 3076880 5071938 4404143 6248733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)IPHISTGDIFR MGYG000000002_00861 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A faecis|m__MGYG000000002 1.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3XZAB@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism 1.0 adk 1.0 - 1.0 2.7.4.3 1.0 ko:K00939 1.0 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 1.0 M00049 1.0 R00127,R01547,R11319 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS20110 1.0 ADK,ADK_lid 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000002_00861 1.0 adenylate kinase. myokinase. Inorganic triphosphate can also act as donor. AMP + ATP = 2 ADP. 1.0 1.0 1.0 1.0 Purine metabolism|Thiamine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00939:adk, AK; adenylate kinase [EC:2.7.4.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1347316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)KFGDLENPLLVSVR MGYG000004221_00458;MGYG000000013_03892;MGYG000002006_01658;MGYG000002099_01951;MGYG000000278_00304;MGYG000002727_00240;MGYG000000245_03386;MGYG000003547_00119;MGYG000002478_03849;MGYG000001780_04079;MGYG000002103_01314;MGYG000002455_03526;MGYG000001707_02428;MGYG000003504_01005;MGYG000004663_01541;MGYG000000194_03193;MGYG000004732_02304;MGYG000003412_01990;MGYG000003422_01232;MGYG000002933_01184;MGYG000000196_02017;MGYG000002794_01254;MGYG000000076_02377;MGYG000003312_03561;MGYG000000231_00504;MGYG000000002_01928 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.2692307692307692 186801|Clostridia 0.7307692307692307 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8076923076923077 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000004221_00458 0.038461538461538464 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 794784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516170 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)LEASGTSGEK MGYG000002549_02274;MGYG000002438_02554;MGYG000001346_00032;MGYG000002478_03973;MGYG000000236_00368;MGYG000001789_02936;MGYG000000196_03749 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,2FNN5@200643|Bacteroidia,4AP04@815|Bacteroidaceae 0.8571428571428571 976|Bacteroidetes 1.0 G 1.0 COG0058 Glucan phosphorylase 0.8571428571428571 glgP 1.0 - 1.0 2.4.1.1,2.4.1.11,2.4.1.8 1.0 ko:K00688,ko:K00691,ko:K16153 1.0 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 1.0 - 1.0 R00292,R01555,R02111 1.0 RC00005,RC00049 1.0 ko00000,ko00001,ko01000,ko01003 1.0 - 1.0 GH65,GT3,GT35 1.0 - 1.0 DUF3417,Glycogen_syn,Phosphorylase 1.0 2.4.1.1 1.0 GT35 1.0 GT35 1.0 GT35 1.0 MGYG000002549_02274 0.14285714285714285 glycogen phosphorylase. | glycogen(starch) synthase. | maltose phosphorylase. polyphosphorylase. | UDP-glucose--glycogen glucosyltransferase. This entry covers several enzymes from different sources that act in vivo on different forms of (1->4)-alpha-D-glucans.-!-Some of these enzymes catalyze the first step in the degradation of large branched glycan polymers - the phosphorolytic cleavage of alpha-1,4-glucosidic bonds from the non-reducing ends of linear poly(1->4)-alpha-D-glucosyl chains within the polymers.-!-The enzyme stops when it reaches the fourth residue away from an alpha-1,6 branching point, leaving a highly branched core known as a limit dextrin.-!-The description (accepted name) of the enzyme should be modified for each specific instance by substituting 'glycogen' with the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, etc. | The description (official name) varies according to the source of the enzyme and the nature of its synthetic product.-!-Glycogen synthase from animal tissues is a complex of a catalytic subunit and the protein glycogenin.-!-The enzyme requires glucosylated glycogenin as a primer; this is the reaction product of EC 2.4.1.186.-!-A similar enzyme utilizes ADP-glucose (cf. EC 2.4.1.21). [(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. | [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D- glucosyl](n+1) + H(+) + UDP. | D-maltose + phosphate = beta-D-glucose 1-phosphate + D-glucose. 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biofilm formation - Escherichia coli|Necroptosis|Insulin signaling pathway|Glucagon signaling pathway|Insulin resistance 1.0 K00688:PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]|K00691:mapA; maltose phosphorylase [EC:2.4.1.8]|K16153:K16153; glycogen phosphorylase/synthase [EC:2.4.1.1 2.4.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1389916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)LEEAGAEVEVK MGYG000000170_00066 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes_A|s__Alistipes_A sp900240235|m__MGYG000000170 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000170_00066 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5505603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)LNYFVDTKNVA MGYG000000243_01886 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01886 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 24772530 0 0 0 24214893 0 0 0 0 26992665 0 0 23821841 0 0 0 0 0 0 0 23454166 0 32415937 0 0 0 0 35320566 36321383 0 38004034 0 0 0 0 0 0 0 295829 0 0 0 395601 0 0 0 0 301768 0 0 454401 0 0 0 0 0 0 0 359651 0 377597 0 0 0 0 549812 225917 0 464057 0 0 0 0 0 0 0 3892014 0 0 0 4905771 0 0 0 0 4306023 0 0 4671543 0 0 0 0 0 0 0 4511869 0 0 0 0 0 0 5278711 4313046 0 4290712 0 0 0 0 0 0 0 0 0 0 0 216158 0 0 0 0 0 0 0 331610 0 0 0 0 0 0 0 319083 0 247889 0 0 0 0 258671 298855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)MGPPQADVALR MGYG000001651_01266 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Anaerovoracaceae|g__UBA1191|s__UBA1191 sp900545775|m__MGYG000001651 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36EI7@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001651_01266 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2888201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)MVVQHNLTAM(Oxidation)NANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.1 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)MVVQHNLTAMNANR MGYG000000997_01685;MGYG000004271_01770;MGYG000000153_01160;MGYG000000389_01367;MGYG000000271_01499;MGYG000000076_03207;MGYG000000404_00502;MGYG000002580_00507;MGYG000002517_00135;MGYG000001141_01878 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.1 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)NFSFQVEEITR MGYG000000243_00698 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia,4AK9A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 peptidyl-prolyl cis-trans isomerase (trigger factor) 1.0 tig 1.0 - 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00698 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)NLDNVVENTTSAESR MGYG000004271_00134 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00134 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 751811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)PVQVNEAAGFVVNR MGYG000004732_01389;MGYG000000325_01144;MGYG000002517_00541;MGYG000001255_01113;MGYG000000245_02020;MGYG000002492_00658 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 I 1.0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 0.6666666666666666 hbd 1.0 - 1.0 1.1.1.157 1.0 ko:K00074 1.0 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 1.0 - 1.0 R01976,R05576,R06941 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 3HCDH,3HCDH_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004732_01389 0.16666666666666666 3-hydroxybutyryl-CoA dehydrogenase. BHBD. - (3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + H(+) + NADPH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Benzoate degradation|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00074:paaH, hbd, fadB, mmgB; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3439355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)QIEETTSDFDREK MGYG000000919_03652;MGYG000000202_00541;MGYG000002992_01078;MGYG000000038_02089;MGYG000003486_00745;MGYG000001607_00737;MGYG000001496_00484;MGYG000000278_02028;MGYG000000179_05119;MGYG000001615_01161;MGYG000000198_00464;MGYG000002445_00865;MGYG000000217_01904;MGYG000003783_01372;MGYG000001367_02937;MGYG000001688_01574;MGYG000001617_04641;MGYG000004087_02347;MGYG000000262_01443;MGYG000001193_01063;MGYG000002247_01828;MGYG000002279_00394 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,21YIV@1506553|Lachnoclostridium 0.4090909090909091 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.9545454545454546 MGYG000000919_03652 0.045454545454545456 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1127131 0 0 0 0 0 1696852 0 0 0 0 0 0 0 0 0 1959435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1251695 +(glycidamide)QLIYTAR MGYG000000127_04024;MGYG000000262_02232;MGYG000000077_02465;MGYG000001707_00050 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,36EDS@31979|Clostridiaceae 0.5 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 1.0 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000127_04024 0.25 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 3057320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)SGEFLPC(Carbamidomethyl)VFHVSAR MGYG000004763_00186 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000004763_00186 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 605230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)TCDDIAAC(Carbamidomethyl)AGDTSIALSR MGYG000000171_00277 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3XZR6@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Acetyl-CoA carboxylase alpha subunit 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_00277 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 740101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)TVVTSMEMFRK MGYG000001500_01929 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter asaccharolyticus|m__MGYG000001500 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,267PG@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001500_01929 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)VITSFAGLR MGYG000002298_00538;MGYG000000038_01495;MGYG000000280_01802;MGYG000000404_00180;MGYG000001619_01503;MGYG000002312_03079;MGYG000000171_00187;MGYG000000255_01681;MGYG000000164_01752;MGYG000000271_03444;MGYG000001683_00852;MGYG000000301_00532;MGYG000002517_00473;MGYG000001311_02981;MGYG000000489_00238;MGYG000000154_01590;MGYG000000142_00484;MGYG000000153_02080;MGYG000000076_01007;MGYG000004087_02481;MGYG000002946_03411;MGYG000000245_01076;MGYG000000031_00359;MGYG000000205_00110;MGYG000002276_00835;MGYG000003074_00570;MGYG000000127_02775;MGYG000000179_02173;MGYG000002279_02522;MGYG000001315_01114;MGYG000004271_01228;MGYG000000212_00378;MGYG000000198_04022 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,27V95@189330|Dorea 0.30303030303030304 186801|Clostridia 1.0 S 0.6060606060606061 FAD dependent oxidoreductase 0.5151515151515151 - 0.9090909090909091 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_00538 0.030303030303030304 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1583490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 677823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)VNFSLEGK MGYG000000243_01545 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1028@1|root,COG1028@2|Bacteria,4NFDX@976|Bacteroidetes,2FMSH@200643|Bacteroidia,4AKTZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Oxidoreductase, short chain dehydrogenase reductase family protein 1.0 idnO 1.0 - 1.0 1.1.1.69 1.0 ko:K00046 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01545 1.0 gluconate 5-dehydrogenase. 5-ketogluconate reductase. - (1) D-gluconate + NADP(+) = 5-dehydro-D-gluconate + H(+) + NADPH. (2) D-gluconate + NAD(+) = 5-dehydro-D-gluconate + H(+) + NADH. 1.0 1.0 1.0 1.0 - 1.0 K00046:idnO; gluconate 5-dehydrogenase [EC:1.1.1.69] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1440353 1633346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)VPAYTVGMVC(Carbamidomethyl)GSGMK MGYG000002953_03277 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__UMGS1202|s__UMGS1202 sp900549565|m__MGYG000002953 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002953_03277 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2148423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)YDSSQGKYALADTVSAGEDSITVDGK MGYG000000280_02459;MGYG000000164_00800 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_02459 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)YIIAPDGLK MGYG000003449_00709 genome d__Bacteria|p__Verrucomicrobiota|c__Verrucomicrobiae|o__Opitutales|f__CAG-312|g__CAG-312|s__CAG-312 sp002405555|m__MGYG000003449 1.0 COG0090@1|root,COG0090@2|Bacteria,46S71@74201|Verrucomicrobia,3K7DN@414999|Opitutae 1.0 414999|Opitutae 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003449_00709 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 3193289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)YSLNDIC(Carbamidomethyl)DEWSR MGYG000003697_02405 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,2FNRM@200643|Bacteroidia,4AKT2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_02405 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 565123 0 1366556 0 0 0 1735198 0 0 0 0 0 7539486 0 0 0 0 0 0 0 1432598 0 4326667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)YTSFAGAPEDAESSVK MGYG000002223_00841;MGYG000001300_02394 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3WGGJ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002223_00841 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01421:yhgE; putative membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1357134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(glycidamide)YYFDTDGK MGYG000000233_01872;MGYG000000205_02372 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG5263@1|root,COG5263@2|Bacteria,1UY86@1239|Firmicutes,24EH1@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Cell wall-binding repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_01872 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34952186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(iTRAQ4plex[AnyN-term](mTRAQ_13C(3)15N(1))KNEGIESIMAVYKK MGYG000002438_01883 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 435591.BDI_2653|- 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01883 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(mTRAQ)GTTSVMFSEVANAPAK MGYG000000273_00425;MGYG000004185_01219;MGYG000002478_00808;MGYG000004797_04277 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0244@1|root,COG0244@2|Bacteria,4NFFK@976|Bacteroidetes,2FSBB@200643|Bacteroidia,22XXG@171551|Porphyromonadaceae 0.75 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 0.75 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000273_00425 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02864:RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(mTRAQ)MASIEAALEKGDVEAAK MGYG000001378_04234;MGYG000000029_00498;MGYG000000196_02323;MGYG000001345_03404;MGYG000000013_01747;MGYG000001433_03806;MGYG000002549_04269;MGYG000000054_02343;MGYG000000098_00597 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_04234 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1782863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(mTRAQ_13C(6)15N(2))ADMVDDAELLELVEMEVR MGYG000002485_02622;MGYG000001485_02164 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,3784P@32066|Fusobacteria 0.5 32066|Fusobacteria 0.5 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.5 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_02622 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(mTRAQ_13C(6)15N(2))AHIAELAVGDAC(Carbamidomethyl)TGSNPR MGYG000004558_00984 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__|m__MGYG000004558 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004558_00984 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 962653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +(mTRAQ_13C(6)15N(2))GGTVTNVDEWGK MGYG000000179_03534;MGYG000004087_00279;MGYG000000198_04385 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,220M9@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Binds together with S18 to 16S ribosomal RNA 1.0 rpsF 1.0 - 1.0 - 1.0 ko:K02990 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03534 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02990:RP-S6, MRPS6, rpsF; small subunit ribosomal protein S6 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5512810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asn)DLKDVEDSNLGLK MGYG000000312_02426;MGYG000003486_02521 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000312_02426 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 573957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 783466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 836698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asn)GIGDLVTYEVK MGYG000000099_01985 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0860@1|root,COG0860@2|Bacteria,1UMXD@1239|Firmicutes,25GRN@186801|Clostridia,26CS5@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 M 1.0 S-layer homology domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_01985 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2224888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 956529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asn)GILFAPGK MGYG000003542_01587;MGYG000001302.1_00046;MGYG000000053_01686 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdh 1.0 GO:0005575,GO:0005623,GO:0009986,GO:0044464 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003542_01587 0.3333333333333333 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 1.0 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asn)VVDAGWMTADHQVGQTGK MGYG000002720_01216 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,3WCFX@538999|Clostridiales incertae sedis 1.0 186801|Clostridia 1.0 C 1.0 PFAM Electron transfer flavoprotein domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01216 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 2408707 0 1701168 0 0 0 0 0 0 0 0 2532045 0 0 0 0 0 0 0 0 2067807 0 0 0 0 2563948 0 0 2325658 0 0 0 0 3045389 0 0 0 0 0 0 368439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asn)YLEAWDTYKEGEK MGYG000004797_03700 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG3172@1|root,COG3172@2|Bacteria,4NEQF@976|Bacteroidetes,2FN8P@200643|Bacteroidia,4AMSQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 COG NOG06391 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4301 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_03700 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340742 0 0 0 0 477947 0 0 0 0 1078780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asp)AAAAAEAEAK MGYG000002293_01607 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01607 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1649360 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asp)AASESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004884_01637 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asp)AGGVILITTK MGYG000002438_00861;MGYG000002218_02008;MGYG000000355_00074;MGYG000002478_00138;MGYG000002834_00163;MGYG000001489_04986;MGYG000003521_00292;MGYG000001666_00694;MGYG000003697_02612;MGYG000002080_00857 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 0.4 976|Bacteroidetes 1.0 P 0.9 TonB-linked outer membrane protein, SusC RagA family 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00861 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 891729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asp)ATFNTVYC(Carbamidomethyl)C(Carbamidomethyl)FYK MGYG000002478_01081 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01081 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2954226 3336163 7312666 0 0 2432910 4786412 0 0 2558802 0 0 0 0 0 0 3495964 982587 2088032 0 0 2347008 1886939 4267095 2092491 2248739 3580436 1806269 3568438 0 0 0 8961813 0 3064044 0 2955322 8199940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asp)AYLFNHVEYR MGYG000004893_00001 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A sp900555485|m__MGYG000004893 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,378RN@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000004893_00001 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 851623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asp)HANADDTWK MGYG000001619_00313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA9502|s__UBA9502 sp900540335|m__MGYG000001619 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001619_00313 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2129521 0 1607912 0 0 3887362 0 0 0 0 1521412 0 754366 0 0 0 0 0 0 0 0 +A(Ala->Asp)LVDGAPK MGYG000003166_01197;MGYG000000053_00901;MGYG000001292_02396;MGYG000001597_00990;MGYG000002619_00763;MGYG000003872_00167;MGYG000001255_00183;MGYG000002082_01855;MGYG000003683_01183;MGYG000001562_01082;MGYG000003279_00958;MGYG000000130_00379;MGYG000000756_00072;MGYG000004006_00426;MGYG000002610_00935;MGYG000002545_02317;MGYG000000258_01583;MGYG000003899_00430;MGYG000001546_01548;MGYG000002977_00165;MGYG000002867_00700;MGYG000003307_00505;MGYG000001420_00134;MGYG000000039_01033;MGYG000002007_00362;MGYG000001300_02635;MGYG000000003_02516;MGYG000002224_00796;MGYG000001613_01124;MGYG000002040_00800;MGYG000001497_00224;MGYG000004158_00987;MGYG000002203_00881;MGYG000000195_00269;MGYG000004756_01180;MGYG000001660_01967;MGYG000003730_01040;MGYG000000074_01766;MGYG000003509_00721;MGYG000002651_00254;MGYG000003542_00372;MGYG000004658_01198;MGYG000000414_00669;MGYG000002397_01219;MGYG000002223_01729;MGYG000002274_01731 domain d__Bacteria 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 0.34782608695652173 186801|Clostridia 0.4782608695652174 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 0.8695652173913043 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_01197 0.021739130434782608 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2876607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asp)MMVGLDGTPEK MGYG000000179_05287 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Arabinose_Isome,Fucose_iso_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_05287 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 973980 0 0 0 0 0 0 0 516502 366789 0 0 0 0 0 0 0 0 0 665817 583042 0 0 0 0 1086487 972320 0 0 634544 0 0 0 497242 0 617983 576747 0 564517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332433 0 0 0 0 0 0 0 0 0 841318 1448107 0 904739 0 0 0 0 0 901378 0 656043 903881 0 0 0 0 0 0 0 0 0 734464 448942 0 0 0 717860 755218 770413 0 0 756527 597835 0 0 751454 0 683648 947950 0 417706 0 0 0 0 0 520999 0 0 201662 0 0 0 0 0 0 0 0 516719 681976 0 0 0 0 238398 351896 763029 0 0 0 309109 0 0 0 0 695130 685761 0 2293488 0 0 0 0 0 1619232 0 1998695 2507444 0 0 0 0 0 0 0 0 2216599 1581885 2910463 0 0 0 2058404 1986508 2498140 0 0 1627389 3749019 0 0 1936427 0 1904274 1629459 0 +A(Ala->Asp)SGRFDDEIVPVPVK MGYG000004482_00909;MGYG000000377_01679 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,2N6SP@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004482_00909 0.5 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 1204007 0 0 0 1704631 0 0 0 1484257 0 0 0 0 0 0 1438508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1174352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1272795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Asp)YKPFAPGASPSYGAEK MGYG000000217_01657 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Acetatifactor|s__Acetatifactor sp900066565|m__MGYG000000217 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,27J0U@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate formate lyase-like 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000217_01657 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8503684 0 0 0 0 7520598 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 499323 0 0 0 0 378587 0 0 0 0 276480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1219198 0 0 0 0 1162782 0 0 0 0 1074145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 630500 0 0 0 0 428592 0 0 0 0 953109 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gln)ADDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1896826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gln)AMEIMR MGYG000002224_01341;MGYG000000084_02152 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes 0.5 1239|Firmicutes 0.5 S 1.0 Myosin-crossreactive antigen 0.5 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002224_01341 0.5 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 - 1.0 K10254:ohyA, sph; oleate hydratase [EC:4.2.1.53] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5077804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gln)DLKDVDDSNLGLK MGYG000001637_02230;MGYG000000154_01281;MGYG000000217_01341 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.6666666666666666 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1397892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gln)GVKPEMVDEVK MGYG000004271_00231;MGYG000000489_01023;MGYG000000271_02104;MGYG000000280_01473;MGYG000001637_02269;MGYG000003694_00877 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00231 0.16666666666666666 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 3126235 2866097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4865524 3228802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)AAGTAAVSAAEQTK MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00272 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01421:yhgE; putative membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1068014 0 0 0 0 1228467 +A(Ala->Glu)AASESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004884_01637 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)AASSFNK MGYG000000198_05930 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Cell wall-binding repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_05930 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1136627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 214330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)ATPLAK MGYG000002279_01986;MGYG000000359_00714 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002279_01986 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2995274 2555781 0 0 0 0 0 0 0 0 0 0 0 1281050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1067180 1303409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4974681 6205444 0 0 0 0 0 0 0 0 0 0 0 3806399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 377317 413854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)AWDALTDAQK MGYG000002720_00991;MGYG000002040_00824;MGYG000002143_00828;MGYG000000369_00585;MGYG000000022_00190;MGYG000002517_01775;MGYG000000489_00610;MGYG000001300_00328;MGYG000002993_01434 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,2N7HM@216572|Oscillospiraceae 0.4444444444444444 186801|Clostridia 1.0 H 1.0 Cobalt chelatase (CbiK) 0.5555555555555556 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 0.6666666666666666 - 1.0 - 1.0 - 0.8888888888888888 - 1.0 MGYG000002720_00991 0.1111111111111111 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 694751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)EREAAEQAK MGYG000002506_02810 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,3XMNK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002506_02810 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 681122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)GLAGLEITC(Carbamidomethyl)PK MGYG000000802_01545;MGYG000000188_00827;MGYG000000333_00450;MGYG000004746_01526;MGYG000002968_00326;MGYG000003274_01601;MGYG000002947_01134;MGYG000003851_00621;MGYG000002065_00755;MGYG000002970_00371;MGYG000002775_01124 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0696@1|root,COG0696@2|Bacteria,2HHGK@201174|Actinobacteria,4CUJ8@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 - 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Metalloenzyme,Phosphodiest,Sulfatase,iPGM_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000802_01545 0.09090909090909091 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K15633:gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1232692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)GTLAVAK MGYG000001300_02037;MGYG000000233_00344 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 G 0.5 Phosphoglycerate kinase 0.5 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02037 0.5 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 687734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3289688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1965310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)GVTADSIAK MGYG000002720_01849;MGYG000004487_00561 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,2N6SP@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01849 0.5 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7476411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8545539 0 0 0 0 0 0 4164682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)IPHVEIVR MGYG000002720_00860;MGYG000004573_00975;MGYG000002926_00665;MGYG000004525_00411;MGYG000002143_01958;MGYG000003919_00339;MGYG000001733_00673;MGYG000004196_01674;MGYG000002574_02767;MGYG000004487_00298;MGYG000001502_02361 domain d__Bacteria 1.0 COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia,25UUF@186806|Eubacteriaceae 0.6363636363636364 186801|Clostridia 0.7272727272727273 E 0.7272727272727273 Lysine-2,3-aminomutase 0.9090909090909091 kamA 0.7272727272727273 - 1.0 5.4.3.2 0.9090909090909091 ko:K01843 0.9090909090909091 ko00310,map00310 1.0 - 1.0 R00461 1.0 RC00303 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,LAM_C,Radical_SAM 0.8181818181818182 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_00860 0.09090909090909091 lysine 2,3-aminomutase. - This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-It contains pyridoxal phosphate and a [4Fe-4S] cluster and binds an exchangeable S-adenosyl-L-methionine molecule.-!-Activity in vitro requires a strong reductant such as dithionite and strictly anaerobic conditions.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of S-adenosyl-L-methionine, mediated by the iron- sulfur cluster.-!-S-adenosyl-L-methionine is regenerated at the end of the reaction. L-lysine = (3S)-3,6-diaminohexanoate. 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Lysine degradation 1.0 K01843:kamA; lysine 2,3-aminomutase [EC:5.4.3.2] 0.9090909090909091 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511325 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)ITGLGLAEAK MGYG000002026_00911 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__HGM13010|s__HGM13010 sp900754965|m__MGYG000002026 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,269AI@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002026_00911 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1900027 0 0 0 0 +A(Ala->Glu)IVKNPGESC(Carbamidomethyl)DEK MGYG000000164_00379;MGYG000000133_02152;MGYG000000249_00984;MGYG000002772_01083;MGYG000001714_00588 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,36G77@31979|Clostridiaceae 0.4 186801|Clostridia 1.0 E 1.0 peptidase 0.4 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_00379 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 388601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 899944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)KEKFER MGYG000000042_01421;MGYG000002106_00224;MGYG000001524_01606;MGYG000001630_01142;MGYG000002485_02622;MGYG000004893_01944;MGYG000004893_00932;MGYG000003460_01161;MGYG000003155_00314;MGYG000001925_01419;MGYG000000273_00431;MGYG000001701_00473;MGYG000004763_01689;MGYG000003681_02037;MGYG000001384_04567;MGYG000001464_00103;MGYG000002281_02290;MGYG000003185_01074;MGYG000003992_01709;MGYG000003142_01879;MGYG000002528_01098;MGYG000001313_00097;MGYG000000013_02251;MGYG000003266_00392;MGYG000003583_01411;MGYG000002455_03884;MGYG000000348_00283;MGYG000003628_01000;MGYG000001485_02164;MGYG000000034_01346;MGYG000001141_02439;MGYG000002930_00867;MGYG000003142_01865;MGYG000000196_03974;MGYG000003375_00698;MGYG000004573_00004;MGYG000001661_02666;MGYG000003851_00676;MGYG000002762_01733;MGYG000000121_02189;MGYG000001789_00154;MGYG000001567_01738;MGYG000000182_00585;MGYG000000054_03933;MGYG000000236_01807;MGYG000000098_02017;MGYG000002291_02272;MGYG000003185_01053;MGYG000002556_01332;MGYG000000036_01380;MGYG000000445_01370;MGYG000001346_01533;MGYG000000243_01988;MGYG000001780_03476;MGYG000002540_03367;MGYG000001646_01118;MGYG000003073_01160;MGYG000003514_00785;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.23728813559322035 976|Bacteroidetes 0.4915254237288136 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.9830508474576272 tuf 1.0 - 0.847457627118644 - 1.0 ko:K02358 0.9830508474576272 - 0.9830508474576272 - 0.9830508474576272 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9830508474576272 - 0.9830508474576272 - 1.0 - 0.9491525423728814 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.01694915254237288 - - - - 1.0 1.0 1.0 1.0 - 0.9830508474576272 K02358:tuf, TUFM; elongation factor Tu 0.9830508474576272 none 1.0 0 0 0 0 0 0 0 3919345 0 0 0 0 0 4818233 0 1044038 0 0 0 0 2631983 4751343 0 0 2753006 0 0 0 0 2954044 0 0 0 3183946 0 0 0 0 0 0 0 0 0 3511410 0 1107512 0 0 0 0 0 1798820 0 1762084 0 0 0 0 1669775 0 0 3033570 2302140 0 0 0 0 1591621 0 0 0 1699616 0 0 0 0 0 0 0 0 0 5573936 0 3841690 0 0 0 0 0 1911641 0 2453630 0 0 0 0 1829163 3576849 0 0 2809754 0 0 0 0 2124568 0 0 0 3364226 0 0 0 0 0 0 0 0 0 6391476 0 5353453 0 0 0 0 0 3168782 0 2634152 0 0 0 0 1587189 5686151 0 5816077 4879284 0 0 0 0 4416713 0 0 0 6803715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)LADSVHAYGTK MGYG000000022_00970 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WH0G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 NADH oxidase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Oxidored_FMN,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00970 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438990 0 0 0 0 443676 0 0 0 0 449591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1271412 0 0 0 0 1549090 0 0 0 0 1372584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)LC(Carbamidomethyl)DTLEGDER MGYG000002223_00163;MGYG000001255_00186;MGYG000002105_01626;MGYG000001300_01405;MGYG000000022_01398 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3WGUG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002223_00163 0.2 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 804404 0 0 0 0 0 0 0 0 0 0 0 0 1028425 0 0 0 0 0 1081770 0 0 0 0 0 649323 633288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 621206 0 0 615759 0 823672 0 0 736944 0 0 0 0 0 0 0 0 0 0 0 762141 0 492493 0 0 0 0 0 0 0 0 0 654755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)LNDIYYGR MGYG000002082_01706 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900544265|m__MGYG000002082 1.0 COG0436@1|root,COG0436@2|Bacteria,4NF2E@976|Bacteroidetes,2FN0N@200643|Bacteroidia,22UX5@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Aminotransferase class I and II 1.0 dapL 1.0 - 1.0 2.6.1.83 1.0 ko:K10206,ko:K14261 1.0 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 1.0 M00527 1.0 R07613 1.0 RC00006,RC01847 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002082_01706 1.0 LL-diaminopimelate aminotransferase. LL-diaminopimelate transaminase. In vivo, the reaction occurs in the opposite direction to that shown above.-!-This is one of the final steps in the lysine biosynthesis pathway of plants (ranging from mosses to flowering plants).-!-Meso-diaminoheptanedioate, an isomer of LL-2,6-diaminoheptanedioate, and the structurally related compounds lysine and ornithine are not substrates.-!-2-oxoglutarate cannot be replaced by oxaloacetate or pyruvate.-!-It is not yet known if the substrate of the biosynthetic reaction is the cyclic or acyclic form of tetrahydropyridine-2,6-dicarboxylate. (2S,6S)-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5- tetrahydrodipicolinate + H(+) + H2O + L-glutamate. 1.0 1.0 1.0 1.0 Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K10206:E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]|K14261:alaC; alanine-synthesizing transaminase [EC:2.6.1.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2059706 0 2165651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)LNLTATLDGAK MGYG000002549_04177 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG1004@1|root,COG1004@2|Bacteria,4NE00@976|Bacteroidetes,2FMZ9@200643|Bacteroidia,4AM97@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family 1.0 ugd 1.0 - 1.0 1.1.1.22 1.0 ko:K00012 1.0 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 1.0 M00014,M00129,M00361,M00362 1.0 R00286 1.0 RC00291 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 MGYG000002549_04177 1.0 UDP-glucose 6-dehydrogenase. - Also acts on UDP-2-deoxyglucose. H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D- glucuronate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Ascorbate and aldarate metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K00012:UGDH, ugd; UDPglucose 6-dehydrogenase [EC:1.1.1.22] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 936902 0 0 0 0 0 0 0 +A(Ala->Glu)MGFEVIDC(Carbamidomethyl)NESDPVEK MGYG000002528_02461 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG1063@1|root,COG1063@2|Bacteria,1V0K3@1239|Firmicutes,24DWK@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02461 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1267392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633753 0 1840454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)SGAGGQC(Carbamidomethyl)VNTTDSAVR MGYG000000271_00850;MGYG000000245_01524;MGYG000003422_01334;MGYG000004271_01559 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA 1.0 prfA 1.0 - 1.0 - 1.0 ko:K02835 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012 1.0 - 1.0 - 1.0 - 1.0 PCRF,RF-1 1.0 - 1.0 - 1.0 - 1.0 GH23 1.0 MGYG000000271_00850 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02835:prfA, MTRF1, MRF1; peptide chain release factor 1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 414904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1232064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)TDQPFLMPVEDVFTITGR MGYG000004735_00884 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00884 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230735535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)TTDKLAGILAAK MGYG000002720_01505 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,2N6RS@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01505 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit|K22431:carD; caffeyl-CoA reductase-Etf complex subunit CarD [EC:1.3.1.108] 1.0 none 1.0 968332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)TTEQAQEVC(Carbamidomethyl)AGIR MGYG000001338_02545 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02545 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 895683 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1130943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3204444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)TVIALNVR MGYG000001346_01583 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1196@1|root,COG1196@2|Bacteria,4PIVU@976|Bacteroidetes,2FQ1R@200643|Bacteroidia,4APFX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 D 1.0 Domain of unknown function 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_01583 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 5530829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)VDC(Carbamidomethyl)DEAVAR MGYG000001225_01793 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Evtepia|s__Evtepia sp004556345|m__MGYG000001225 1.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3WGQA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 acetylornithine aminotransferase 1.0 argD 1.0 - 1.0 2.6.1.11,2.6.1.17 1.0 ko:K00821 1.0 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00028,M00845 1.0 R02283,R04475 1.0 RC00006,RC00062 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001225_01793 1.0 acetylornithine transaminase. | succinyldiaminopimelate transaminase. succinylornithine aminotransferase. | succinyldiaminopimelate transferase. Also acts on L-ornithine and N(2)-succinyl-L-ornithine. 2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L- glutamate 5-semialdehyde. | 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (S)-2- succinylamino-6-oxoheptanedioate + L-glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00821:argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5615095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)VSMEDIK MGYG000003535_00725 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp004556065|m__MGYG000003535 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003535_00725 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 1279284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2378081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Glu)VSMEDIKK MGYG000003535_00725 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp004556065|m__MGYG000003535 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003535_00725 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3352195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)AHFGNNVSHSHR MGYG000000184_00823;MGYG000001338_01758 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL28 family 1.0 rpmB 1.0 - 1.0 - 1.0 ko:K02902 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_00823 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02902:RP-L28, MRPL28, rpmB; large subunit ribosomal protein L28 1.0 none 1.0 0 0 480084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112079 0 0 0 0 202047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2030210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2677053 0 0 0 0 1126511 +A(Ala->Gly)AMLAIMNPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)AMLTIMNPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)ASEFEALR MGYG000002717_02115;MGYG000001661_02103;MGYG000001313_03171;MGYG000000098_00636;MGYG000000054_02931;MGYG000000196_02287;MGYG000003681_00141;MGYG000004763_00640;MGYG000001346_00856 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 0.8888888888888888 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 0.8888888888888888 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002717_02115 0.1111111111111111 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)DDIALLK MGYG000001599_02718 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900544075|m__MGYG000001599 1.0 COG4115@1|root,COG4115@2|Bacteria,4NUMR@976|Bacteroidetes,2FUIS@200643|Bacteroidia,4ASEK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 YoeB-like toxin of bacterial type II toxin-antitoxin system 1.0 - 1.0 - 1.0 - 1.0 ko:K19158 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko02048 1.0 - 1.0 - 1.0 - 1.0 YoeB_toxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001599_02718 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K19158:yoeB; toxin YoeB [EC:3.1.-.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 486833 0 0 0 0 505921 0 0 0 0 408452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275804 0 0 0 0 0 0 0 0 0 182765 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253129 0 0 0 0 228660 0 0 0 0 198197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2630328 0 0 0 0 2417287 0 0 0 0 2644608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394309 0 0 0 0 299529 0 0 0 0 317346 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)IYVVLDK MGYG000000243_01886;MGYG000002171_01694 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01886 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 5315458 0 0 0 0 4961401 0 0 7676985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1524411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)LGLLFAPEKGEDTR MGYG000000196_04764;MGYG000003681_01676;MGYG000000105_00790;MGYG000000236_02677;MGYG000001461_03645;MGYG000001345_02126;MGYG000004876_01798;MGYG000004899_00075 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4980@1|root,COG4980@2|Bacteria,4NXMW@976|Bacteroidetes,2FUB7@200643|Bacteroidia,4ARS7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG35214 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 YtxH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04764 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)LLDYLK MGYG000000236_03731 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,2FTTZ@200643|Bacteroidia,4ARAW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_03731 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02956:RP-S15, MRPS15, rpsO; small subunit ribosomal protein S15 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1064534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)NPILLEPIMK MGYG000003423_00914 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__W3P20-009|g__W3P20-009|s__W3P20-009 sp900766825|m__MGYG000003423 1.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,47M8E@768503|Cytophagia 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000003423_00914 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 387107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)QLEETTSEFDKEK MGYG000000231_00495;MGYG000004271_02056;MGYG000000187_01409;MGYG000000404_00409;MGYG000000271_00294;MGYG000002528_02459;MGYG000004707_00421;MGYG000001707_02383 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia 0.375 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000231_00495 0.125 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1085726 0 0 0 0 0 0 0 0 0 1528601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1242457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)QTFELYAIK MGYG000001661_01211;MGYG000003681_02216;MGYG000001313_00227;MGYG000004899_00384 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001661_01211 0.25 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03072:secD; preprotein translocase subunit SecD|K12257:secDF; SecD/SecF fusion protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1496142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)VTETVTQPVGFR MGYG000000074_01087 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG3250@1|root,COG3250@2|Bacteria,4NF3W@976|Bacteroidetes,2FM0P@200643|Bacteroidia,22V3F@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Beta galactosidase small chain 1.0 - 1.0 - 1.0 3.2.1.23 1.0 ko:K01190 1.0 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 1.0 - 1.0 R01105,R01678,R03355,R04783,R06114 1.0 RC00049,RC00452 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N 1.0 3.2.1.23 1.0 GH2 1.0 GH2 1.0 GH2 1.0 MGYG000000074_01087 1.0 beta-galactosidase. lactase. Some enzymes in this group hydrolyze alpha-L-arabinosides; some animal enzymes also hydrolyze beta-D-fucosides and beta-D-glucosides (cf. EC 3.2.1.108). Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D- galactosides. 1.0 1.0 1.0 1.0 Galactose metabolism|Other glycan degradation|Sphingolipid metabolism|Metabolic pathways 1.0 K01190:lacZ; beta-galactosidase [EC:3.2.1.23] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1861798 0 0 0 0 0 0 0 0 0 0 1503535 0 0 0 0 0 0 0 0 +A(Ala->Gly)VVTAFVDGWAK MGYG000002040_01179;MGYG000000195_01879 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 GH49 1.0 MGYG000002040_01179 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 220751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 725253 0 0 0 0 0 0 0 0 569830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)YASNAANFEDTAK MGYG000001750_01297 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola ilei|m__MGYG000001750 1.0 COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,2FNB4@200643|Bacteroidia,4ANUZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 with different specificities (related to short-chain alcohol 1.0 fabG 1.0 - 1.0 1.1.1.100 1.0 ko:K00059 1.0 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 1.0 M00083,M00572 1.0 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001750_01297 1.0 3-oxoacyl-[acyl-carrier-protein] reductase. - Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates. a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis|Prodigiosin biosynthesis|Biotin metabolism|Biosynthesis of unsaturated fatty acids|Metabolic pathways|Fatty acid metabolism 1.0 K00059:fabG, OAR1; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1402348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)YASNAASFEDTAK MGYG000001661_02228;MGYG000003681_02278 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,2FNB4@200643|Bacteroidia,4ANUZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 with different specificities (related to short-chain alcohol 1.0 fabG 1.0 - 1.0 1.1.1.100 1.0 ko:K00059 1.0 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 1.0 M00083,M00572 1.0 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001661_02228 0.5 3-oxoacyl-[acyl-carrier-protein] reductase. - Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates. a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis|Prodigiosin biosynthesis|Biotin metabolism|Biosynthesis of unsaturated fatty acids|Metabolic pathways|Fatty acid metabolism 1.0 K00059:fabG, OAR1; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2746067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Gly)YDSFQFVR MGYG000001687_02017;MGYG000000095_04521;MGYG000000271_00685;MGYG000002989_00673;MGYG000002492_01449;MGYG000004271_02184;MGYG000000077_00482;MGYG000002517_01100;MGYG000000359_01824;MGYG000000489_02027 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia 0.8 186801|Clostridia 1.0 J 1.0 Glutaminyl-tRNA synthetase 0.8 glnS 1.0 - 1.0 6.1.1.18 1.0 ko:K01886 1.0 ko00970,ko01100,map00970,map01100 1.0 M00359,M00360 1.0 R03652 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 tRNA-synt_1c,tRNA-synt_1c_C 1.0 - 1.0 - 1.0 - 1.0 CE8 1.0 MGYG000001687_02017 0.1 glutamine--tRNA ligase. glutaminyl-tRNA synthetase. - ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl- tRNA(Gln). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis|Metabolic pathways 1.0 K01886:QARS, glnS; glutaminyl-tRNA synthetase [EC:6.1.1.18] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1212869 0 0 0 0 0 0 0 +A(Ala->Lys)AEILQISK MGYG000000427_00123 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__RFN20|f__CAG-449|g__CAG-449|s__CAG-449 sp000432895|m__MGYG000000427 1.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,3VNPX@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 P 1.0 Belongs to the ABC transporter superfamily 1.0 - 1.0 - 1.0 - 1.0 ko:K10112 1.0 ko02010,map02010 1.0 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1 1.0 - 1.0 - 1.0 ABC_tran,TOBE_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000427_00123 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10112:msmX, msmK, malK, sugC, ggtA, msiK; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 7142402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Lys)DLKPHAPR MGYG000004797_03519 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004797_03519 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640364 0 0 0 0 0 0 694096 0 0 0 0 0 0 0 0 0 0 0 0 0 339149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Lys)IAEELVNLTVK MGYG000002540_03361;MGYG000001164_01590;MGYG000001056_00099;MGYG000001659_00517;MGYG000003697_01479;MGYG000004848_00672;MGYG000003374_00514;MGYG000002603_01776;MGYG000002080_00533;MGYG000004495_01664;MGYG000003353_00116;MGYG000002293_00514;MGYG000004757_00587;MGYG000003301_00858 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia 0.5714285714285714 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002540_03361 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 933381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Lys)LLDYLK MGYG000000236_03731 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0184@1|root,COG0184@2|Bacteria,4NS7U@976|Bacteroidetes,2FTTZ@200643|Bacteroidia,4ARAW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_03731 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02956:RP-S15, MRPS15, rpsO; small subunit ribosomal protein S15 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2454087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2087296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Lys)LSTDLADQGK MGYG000000044_01042 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides merdae|m__MGYG000000044 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000044_01042 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1932017 0 1968400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1986937 0 0 0 0 1820454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Lys)SGGGYAISIK MGYG000002171_00690 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002493165|m__MGYG000002171 1.0 COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,2FKZT@200643|Bacteroidia,4AMS4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG NOG06228 non supervised orthologous group 1.0 susB 1.0 GO:0000272,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0004558,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:0090599,GO:1901575 1.0 3.2.1.20,3.2.1.3 1.0 ko:K01187,ko:K21574 1.0 ko00052,ko00500,ko01100,map00052,map00500,map01100 1.0 - 1.0 R00028,R00801,R00802,R01790,R01791,R06087,R06088 1.0 RC00028,RC00049,RC00077 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH31,GH97 1.0 - 1.0 GH97_C,GH97_N,Glyco_hydro_97 1.0 3.2.1.3|3.2.1.20 1.0 GH97 1.0 GH97 1.0 GH97 1.0 MGYG000002171_00690 1.0 alpha-glucosidase. | glucan 1,4-alpha-glucosidase. maltase-glucoamylase. | lysosomal alpha-glucosidase. Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.-!-The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links. | Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides.-!-This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides.-!-EC 3.2.1.20 from mammalian intestine can catalyze similar reactions. Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. | Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose. 1.0 1.0 1.0 1.0 Galactose metabolism|Starch and sucrose metabolism|Metabolic pathways 1.0 K01187:malZ; alpha-glucosidase [EC:3.2.1.20]|K21574:susB; glucan 1,4-alpha-glucosidase [EC:3.2.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3546178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Lys)YENGVLTGK MGYG000002485_00504;MGYG000000233_02492 domain d__Bacteria 1.0 COG0334@1|root,COG0334@2|Bacteria,378XT@32066|Fusobacteria 0.5 32066|Fusobacteria 0.5 C 0.5 Belongs to the Glu Leu Phe Val dehydrogenases family 0.5 gluD 0.5 - 0.5 1.4.1.2,1.4.1.4 0.5 ko:K00260,ko:K00262 0.5 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 0.5 - 0.5 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 0.5 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_00504 0.5 glutamate dehydrogenase. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.5 0.5 0.5 0.5 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Taurine and hypotaurine metabolism|Nitrogen metabolism|Metabolic pathways 0.5 K00260:gudB, rocG; glutamate dehydrogenase [EC:1.4.1.2]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Met)LGTGVEKDGNIDSTPVGTNADGTATVVK MGYG000000179_01753 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_01753 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Phe)NIPGFR MGYG000004797_02839;MGYG000002478_00469;MGYG000000243_00698 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia,4AK9A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 peptidyl-prolyl cis-trans isomerase (trigger factor) 1.0 tig 1.0 - 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_02839 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 689892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Pro)ADDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 637576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1433019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Pro)EGTPEEIVPAR MGYG000003383_02109;MGYG000001292_00431;MGYG000003683_01237;MGYG000001490_00221;MGYG000002469_00458;MGYG000002395_00255;MGYG000000756_00019 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4CYVV@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGE-sulfatase,Glucosamine_iso,PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003383_02109 0.14285714285714285 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 1074458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1262887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 702197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1352694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)AASESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 837119 0 0 0 0 0 0 0 2074205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325663 0 0 0 0 533112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)ADDAAGLSISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001777_01322 0.022727272727272728 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 2025243 0 0 1878988 1596316 0 0 1289800 0 0 1707062 1212119 0 0 0 0 0 1431711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276437 0 0 0 0 0 0 245164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328597 0 0 0 0 0 462979 493931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475859 0 0 907647 437222 0 0 514312 0 0 643978 571850 0 0 0 0 0 421976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)AGAAGVIRPSK MGYG000001300_00059;MGYG000003899_00538;MGYG000002641_02329;MGYG000002610_01595;MGYG000004719_01899;MGYG000003166_01772;MGYG000003921_01901;MGYG000001157_01521;MGYG000003937_01168;MGYG000000573_01714;MGYG000000589_01770;MGYG000000084_01199;MGYG000004732_01998 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 0.9230769230769231 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 0.9230769230769231 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00059 0.07692307692307693 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Phosphotransferase system (PTS) 1.0 K02803:nagEb; N-acetylglucosamine PTS system EIIB component [EC:2.7.1.193]|K02804:nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 962875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1373515 0 1284797 0 0 0 +A(Ala->Ser)AGNAFFEIAAK MGYG000000216_00086;MGYG000000142_00725 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1879@1|root,COG1879@2|Bacteria,1TRBC@1239|Firmicutes,24APE@186801|Clostridia,3Y16X@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 lsrB 1.0 - 1.0 - 1.0 ko:K10555 1.0 ko02010,ko02024,map02010,map02024 1.0 M00219 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.8 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000216_00086 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 1.0 K10555:lsrB; AI-2 transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)ANAGGVATSALEMSQNSER MGYG000002945_01156;MGYG000000080_02138;MGYG000004689_01489;MGYG000000245_02477;MGYG000000135_03486;MGYG000004839_02530;MGYG000000251_03197;MGYG000000146_00040;MGYG000002212_01108;MGYG000000164_00589;MGYG000000153_01021;MGYG000004296_00383;MGYG000004380_02235;MGYG000000404_01723;MGYG000002517_02750;MGYG000001797_03050;MGYG000000312_01079;MGYG000001637_01313;MGYG000001689_00608;MGYG000000489_02253;MGYG000000280_02447;MGYG000002528_01412;MGYG000003425_04268;MGYG000000076_02271;MGYG000004879_02390;MGYG000000229_01813;MGYG000002670_01100;MGYG000000136_01003;MGYG000002609_02276;MGYG000004719_01514;MGYG000004547_00997;MGYG000003702_00540;MGYG000004055_01618;MGYG000003063_02071;MGYG000000187_02311;MGYG000002279_01299;MGYG000002149_01514;MGYG000002992_01902;MGYG000000271_00907;MGYG000002492_02848;MGYG000002131_02188 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.3170731707317073 186801|Clostridia 0.6829268292682927 C 0.4146341463414634 Belongs to the Glu Leu Phe Val dehydrogenases family 0.4634146341463415 gdhA 0.6829268292682927 - 1.0 1.4.1.3,1.4.1.4 0.6341463414634146 ko:K00261,ko:K00262 0.6341463414634146 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6341463414634146 M00740 0.6829268292682927 R00243,R00248 0.6829268292682927 RC00006,RC02799 0.6829268292682927 ko00000,ko00001,ko00002,ko01000,ko04147 0.6829268292682927 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.6829268292682927 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002945_01156 0.024390243902439025 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6341463414634146 0.6341463414634146 0.6341463414634146 0.6341463414634146 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.6341463414634146 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.6341463414634146 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1269544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)ANLPEAMIQNIAK MGYG000002171_01964 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002493165|m__MGYG000002171 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_01964 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 649501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1553269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1278607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)ANVTLVGYEK MGYG000001065_00275;MGYG000001622_00878 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001065_00275 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11942269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42021232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49150122 0 +A(Ala->Ser)APILLEPIMR MGYG000000171_02843;MGYG000004733_01212 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000000171_02843 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)ATDGPMPQTR MGYG000000042_01421;MGYG000004732_02398;MGYG000004464_00178;MGYG000002619_00483;MGYG000000412_01546;MGYG000004848_00666;MGYG000004565_01266;MGYG000003353_00058;MGYG000003189_00640;MGYG000003460_01161;MGYG000003324_00542;MGYG000001806_01406;MGYG000001701_00473;MGYG000004763_01689;MGYG000003681_02037;MGYG000003184_03610;MGYG000003363_01661;MGYG000003937_01027;MGYG000001234_01151;MGYG000001770_01653;MGYG000003992_01709;MGYG000001313_00097;MGYG000002654_00465;MGYG000004629_00424;MGYG000002455_03884;MGYG000000348_00283;MGYG000002515_03657;MGYG000000044_01721;MGYG000001360_01239;MGYG000002834_01866;MGYG000003549_00407;MGYG000003189_01066;MGYG000002059_00460;MGYG000003152_01866;MGYG000000196_03974;MGYG000004588_00463;MGYG000003375_00698;MGYG000004573_00004;MGYG000001713_03599;MGYG000001661_02666;MGYG000003374_00521;MGYG000001300_00280;MGYG000001635_01137;MGYG000002762_01733;MGYG000003334_00997;MGYG000002040_01212;MGYG000000054_03933;MGYG000002293_00521;MGYG000000098_02017;MGYG000002080_00527;MGYG000001359_01254;MGYG000002438_02321;MGYG000002556_01332;MGYG000003410_00864;MGYG000001346_01533;MGYG000002976_00273;MGYG000001763_00317;MGYG000003812_01875;MGYG000003497_00215;MGYG000004754_01565;MGYG000001692_03322;MGYG000002768_00022;MGYG000003921_01124;MGYG000002996_00986;MGYG000002418_00753;MGYG000002506_03686;MGYG000000168_03211;MGYG000001334_00218;MGYG000004757_00594;MGYG000001487_02232;MGYG000000138_00665;MGYG000002603_01782;MGYG000001630_01142;MGYG000001516_01186;MGYG000000215_00564;MGYG000002535_04656;MGYG000001925_01419;MGYG000002515_03208;MGYG000000273_00431;MGYG000003372_03275;MGYG000004788_02115;MGYG000000230_00429;MGYG000003202_00129;MGYG000002281_02290;MGYG000002506_02966;MGYG000001400_03001;MGYG000003546_00955;MGYG000001554_00107;MGYG000000022_02283;MGYG000002470_01245;MGYG000003446_00658;MGYG000001552_00984;MGYG000002514_02415;MGYG000003899_01642;MGYG000000013_02251;MGYG000003691_01713;MGYG000003394_01668;MGYG000002895_00716;MGYG000002951_00422;MGYG000003697_01485;MGYG000000134_02651;MGYG000001784_02227;MGYG000002507_00346;MGYG000001655_02933;MGYG000000173_00405;MGYG000002220_00457;MGYG000002195_01684;MGYG000000226_00644;MGYG000002930_00867;MGYG000003166_01350;MGYG000002905_00001;MGYG000001590_00854;MGYG000002444_02629;MGYG000002514_01953;MGYG000002912_01340;MGYG000003424_00456;MGYG000001789_00154;MGYG000000236_01807;MGYG000003701_03123;MGYG000000084_02000;MGYG000002291_02272;MGYG000002502_01846;MGYG000004300_00119;MGYG000002641_00069;MGYG000000733_01034;MGYG000002997_01472;MGYG000004221_01651;MGYG000002272_01482;MGYG000000622_01283;MGYG000000243_01988;MGYG000001780_03476;MGYG000000045_02616;MGYG000002540_03367;MGYG000001421_00009;MGYG000000254_02569;MGYG000003660_00194;MGYG000003514_00785;MGYG000003620_01283;MGYG000000117_01463;MGYG000003535_00219;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.1773049645390071 976|Bacteroidetes 0.46808510638297873 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.900709219858156 tuf 1.0 - 0.8368794326241135 - 1.0 ko:K02358 0.9290780141843972 - 0.9290780141843972 - 0.9290780141843972 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.9290780141843972 - 0.9290780141843972 - 1.0 - 0.9645390070921985 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.0070921985815602835 - - - - 1.0 1.0 1.0 1.0 - 0.9290780141843972 K02358:tuf, TUFM; elongation factor Tu 0.9290780141843972 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1557250 0 0 0 0 0 0 0 0 0 0 1060948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)AVDAGAASAR MGYG000002854_00976 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Peptostreptococcaceae|g__Peptacetobacter|s__Peptacetobacter sp900539645|m__MGYG000002854 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,22HEI@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002854_00976 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5676261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)AVETGADAAGR MGYG000000249_01483;MGYG000004799_00497;MGYG000001379_02073;MGYG000000268_01898;MGYG000002596_02056 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_01483 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1246483 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)AVFYGK MGYG000000095_02180 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__GCA-900066755|s__GCA-900066755 sp902363085|m__MGYG000000095 1.0 COG1063@1|root,COG1063@2|Bacteria,1UUV0@1239|Firmicutes,25MAN@186801|Clostridia,3Y1TA@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Alcohol dehydrogenase GroES-like domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000095_02180 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 4022608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)DAATTIIPLDK MGYG000002560_04324 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp902388365|m__MGYG000002560 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002560_04324 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)DDDFRK MGYG000004006_01512 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp000434235|m__MGYG000004006 1.0 COG1834@1|root,COG1834@2|Bacteria,4NFQ7@976|Bacteroidetes,2FNG1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 COG NOG25454 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004006_01512 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 548210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)DLEGYLK MGYG000001255_00113;MGYG000001300_00595 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,3WJGA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001255_00113 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 1754028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)DLGALQNR MGYG000002934_00200 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Caproiciproducens|s__Caproiciproducens sp900546895|m__MGYG000002934 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 hag 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002934_00200 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 6047675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4544998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)EDNPWEQLK MGYG000002040_01384;MGYG000002272_02217;MGYG000001255_00085;MGYG000000195_02259 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3WGII@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 IJM 1.0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002040_01384 0.25 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1|K03527:ispH, lytB; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1063015 0 0 0 0 1270526 0 0 0 0 1095481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518908 0 0 0 0 429000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)ENMQTAESR MGYG000000187_02577 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,25VSN@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000187_02577 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)ENTQSAESR MGYG000004271_01770 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01770 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1238979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)EVVKKPLKITETVLR MGYG000000271_00472 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 carboxylase 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00472 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)FIVTDSFLYK MGYG000001496_03152;MGYG000001954_02140;MGYG000001607_02072;MGYG000000249_01522;MGYG000000179_02579;MGYG000000392_01607;MGYG000000146_01010;MGYG000004779_01269;MGYG000000036_00973;MGYG000002279_01040;MGYG000002004_00639;MGYG000000268_01541;MGYG000000038_01608;MGYG000001311_01191;MGYG000001564_02820;MGYG000002829_01933;MGYG000000198_05065;MGYG000001379_01314;MGYG000002912_00827;MGYG000001310_00117;MGYG000000175_03076;MGYG000000402_01136;MGYG000001531_00350;MGYG000000258_01863;MGYG000004087_01471;MGYG000002772_01870 phylum d__Bacteria|p__Firmicutes_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 0.8076923076923077 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001496_03152 0.038461538461538464 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 108547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189478 0 0 0 0 0 0 0 364523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308923 0 0 0 0 360653 0 0 235917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1700420 0 0 0 0 113412 +A(Ala->Ser)FVAGADIGEMSTLTK MGYG000002156_02025;MGYG000002794_01606 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,4BXEG@830|Butyrivibrio 1.0 186801|Clostridia 1.0 I 1.0 Enoyl-CoA hydratase/isomerase 1.0 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002156_02025 0.5 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1298181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)GAFKDEIVPVEVK MGYG000000233_02446 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,4BWBU@830|Butyrivibrio 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02446 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 2918301 0 0 0 0 2797022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2907434 0 4213936 0 0 0 0 0 3798189 0 0 5018977 0 0 0 0 0 0 0 0 0 0 5156824 0 0 0 0 4289681 0 2680681 0 0 0 0 0 3050874 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2144148 1332541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3534979 0 0 0 0 0 0 0 0 0 0 0 3193628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 685216 +A(Ala->Ser)GAFKDEIVPVEVKK MGYG000000233_02446 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,4BWBU@830|Butyrivibrio 1.0 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02446 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 156132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 533745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)GDTITVAYR MGYG000001306_03854;MGYG000004479_03019;MGYG000004797_00028;MGYG000000042_00899;MGYG000001599_02656;MGYG000003693_02594;MGYG000000243_01801;MGYG000002935_00735;MGYG000001783_01702;MGYG000000273_02944;MGYG000000781_00438;MGYG000001364_03460;MGYG000002478_00167;MGYG000002560_01858;MGYG000003498_00929;MGYG000001925_02300;MGYG000000043_02305;MGYG000003363_03253 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0335@1|root,COG0335@2|Bacteria,4NNPW@976|Bacteroidetes,2FSHU@200643|Bacteroidia,4AQXS@815|Bacteroidaceae 0.9444444444444444 976|Bacteroidetes 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02884 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_03854 0.05555555555555555 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02884:RP-L19, MRPL19, rplS; large subunit ribosomal protein L19 1.0 none 1.0 0 0 359916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1125145 1259497 0 0 807821 0 0 0 0 0 0 0 704863 0 0 0 925441 0 0 0 0 0 751240 0 0 0 0 0 0 0 0 1429235 0 0 0 0 +A(Ala->Ser)GEVPEAIR MGYG000001564_01916;MGYG000000087_01006;MGYG000000909_01230;MGYG000001619_00817;MGYG000001199_01751;MGYG000000194_02265;MGYG000000198_04904;MGYG000001688_04193;MGYG000000274_01720;MGYG000000205_02187 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,21YA9@1506553|Lachnoclostridium 0.8 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001564_01916 0.1 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5127979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)GILNPVTK MGYG000000031_00355 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066205|m__MGYG000000031 1.0 COG2055@1|root,COG2055@2|Bacteria 1.0 2|Bacteria 1.0 C 1.0 Belongs to the LDH2 MDH2 oxidoreductase family 1.0 mdh 1.0 - 1.0 1.1.1.350 1.0 ko:K00073 1.0 ko00230,ko01120,map00230,map01120 1.0 - 1.0 R02935,R02936 1.0 RC00169 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ldh_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_00355 1.0 ureidoglycolate dehydrogenase (NAD(+)). - Involved in catabolism of purines.-!-The enzyme from the bacterium Escherichia coli is specific for NAD(+). cf. EC 1.1.1.154. (S)-ureidoglycolate + NAD(+) = H(+) + N-carbamoyl-2-oxoglycine + NADH. 1.0 1.0 1.0 1.0 Purine metabolism|Microbial metabolism in diverse environments 1.0 K00073:allD; ureidoglycolate dehydrogenase (NAD+) [EC:1.1.1.350] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1771900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)GMGYC(Carbamidomethyl)GAK MGYG000004769_00915 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H2GU@909932|Negativicutes 1.0 909932|Negativicutes 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_00915 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1590811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)GYWHLFR MGYG000003355_02242 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnoclostridium|s__Lachnoclostridium phytofermentans_A|m__MGYG000003355 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,21YPK@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000003355_02242 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 59695 0 0 0 45323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7551002 0 0 0 451356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 638328 0 0 0 0 0 0 0 +A(Ala->Ser)HILTGLPDTYGR MGYG000000479_01151 genome d__Bacteria|p__Spirochaetota|c__Spirochaetia|o__Treponematales|f__Treponemataceae|g__Treponema_D|s__Treponema_D sp900541995|m__MGYG000000479 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,268DX@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate formate lyase-like 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000479_01151 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 763471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)IDDNILNIYK MGYG000002281_03314;MGYG000000196_02520;MGYG000001345_00571 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,4AMRT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 GK 1.0 Psort location Cytoplasmic, score 9.26 1.0 glk 1.0 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_03314 0.3333333333333333 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Galactose metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Neomycin, kanamycin and gentamicin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00845:glk; glucokinase [EC:2.7.1.2] 1.0 none 1.0 1265940 1187177 0 0 0 0 0 0 0 1301350 0 0 0 0 0 0 1151673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 840396 0 0 0 0 0 0 0 0 0 0 285345 0 0 0 0 0 0 479793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)IDINSLK MGYG000000236_02872 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0102@1|root,COG0102@2|Bacteria,4NNGA@976|Bacteroidetes,2FS3I@200643|Bacteroidia,4AM76@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly 1.0 rplM 1.0 - 1.0 - 1.0 ko:K02871 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_02872 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02871:RP-L13, MRPL13, rplM; large subunit ribosomal protein L13 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2273938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)IDPVNDDLVVLNNR MGYG000001552_00916 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Marinifilaceae|g__Butyricimonas|s__Butyricimonas synergistica|m__MGYG000001552 1.0 COG3391@1|root,COG3391@2|Bacteria,4NJJN@976|Bacteroidetes,2FNI0@200643|Bacteroidia,22Z3Y@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 amine dehydrogenase activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001552_00916 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1731201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632592 0 0 0 0 0 0 0 +A(Ala->Ser)IEAVDEC(Carbamidomethyl)VGK MGYG000000164_00796;MGYG000000255_02926;MGYG000000038_02188;MGYG000000233_02244;MGYG000000205_01016;MGYG000004799_00701;MGYG000001602_01797;MGYG000002279_00560;MGYG000000146_00360;MGYG000002992_00161;MGYG000001315_01695 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,27V4Y@189330|Dorea 0.45454545454545453 186801|Clostridia 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 - 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Metalloenzyme,PglZ,Phosphodiest,iPGM_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_00796 0.09090909090909091 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K15633:gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)ILDEATDPWGIK MGYG000003589_00770;MGYG000002182_00653;MGYG000002993_00293;MGYG000002926_00988;MGYG000002707_00629;MGYG000000223_01135;MGYG000004285_00398;MGYG000002485_01701;MGYG000001008_02199;MGYG000000380_00607 domain d__Bacteria 1.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,2N6P2@216572|Oscillospiraceae 0.3 186801|Clostridia 0.7 O 1.0 prohibitin homologues 0.4 qmcA 0.7 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Band_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003589_00770 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 147025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 922840 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)KGKPIVNSADAGDR MGYG000003821_01555;MGYG000001338_02424;MGYG000002966_01692;MGYG000004785_01065;MGYG000000184_00686;MGYG000000200_00066;MGYG000002312_01594;MGYG000000213_00152 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3XZQ5@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 8.87 1.0 acsE 1.0 - 1.0 2.1.1.258 1.0 ko:K15023 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R02289,R10243 1.0 RC00004,RC00113,RC01144,RC02871,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pterin_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003821_01555 0.125 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the N(5) group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein.-!-Involved, together with EC 1.2.7.4 and EC 2.3.1.169, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea. (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein] = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K15023:acsE; 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563249 0 0 0 0 927022 0 0 0 552009 0 0 0 0 0 0 0 620371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)KVDAAIDTK MGYG000001780_02426 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__|m__MGYG000001780 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001780_02426 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1561372 0 743488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)LDNVTVSTITSHK MGYG000001370_00939 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fluxus|m__MGYG000001370 1.0 COG1882@1|root,COG1882@2|Bacteria,4NDWW@976|Bacteroidetes,2FMC2@200643|Bacteroidia,4AM54@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 9.97 1.0 pflB 1.0 - 1.0 2.3.1.54 1.0 ko:K00656 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001370_00939 1.0 formate C-acetyltransferase. pyruvate formate-lyase. - acetyl-CoA + formate = CoA + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1309750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)LEEAGAEVEVK MGYG000002514_01947;MGYG000003539_00331;MGYG000002506_03692;MGYG000002323_03990;MGYG000002415_01567;MGYG000002507_00340 domain d__Bacteria 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria 0.3333333333333333 1236|Gammaproteobacteria 0.8333333333333334 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 0.8333333333333334 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002514_01947 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)LEEVVVVGYATVK MGYG000000236_02987 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_02987 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 801285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)LNEVVVIGYGR MGYG000002960_00779 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900555035|m__MGYG000002960 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 susC 1.0 - 1.0 - 1.0 ko:K21573 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14.6.1 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002960_00779 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21573:susC; TonB-dependent starch-binding outer membrane protein SusC 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 751341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)LREEDVEFK MGYG000000045_02624 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,3XYKH@572511|Blautia 1.0 186801|Clostridia 1.0 L 1.0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity 1.0 mutS2 1.0 - 1.0 - 1.0 ko:K07456 1.0 ko03430,map03430 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03400 1.0 - 1.0 - 1.0 - 1.0 MutS_III,MutS_V,Smr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000045_02624 1.0 - - - - 1.0 1.0 1.0 1.0 Mismatch repair 1.0 K07456:mutS2; DNA mismatch repair protein MutS2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 965863 0 0 0 0 504419 0 0 0 0 621109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312365 0 0 0 0 531991 0 0 0 0 629055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104750 0 0 0 0 0 0 0 0 0 204461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)LTEEEAK MGYG000000099_02570 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000099_02570 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7285775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)LVAAGPKL MGYG000003535_01089;MGYG000001306_02577;MGYG000004479_02615;MGYG000003521_00688;MGYG000003693_02275;MGYG000002540_00741;MGYG000004824_00239;MGYG000001164_02313;MGYG000002455_01424;MGYG000004495_01226;MGYG000000273_00474;MGYG000003282_01713;MGYG000004763_01642;MGYG000003363_00033;MGYG000000415_02204;MGYG000001345_04617;MGYG000000451_00938;MGYG000000196_01785;MGYG000002549_03009;MGYG000001655_03297;MGYG000001551_02111;MGYG000000781_01597;MGYG000003681_02208;MGYG000001346_02112;MGYG000002506_03025;MGYG000000174_04897;MGYG000001599_00077;MGYG000003546_01574;MGYG000000043_00605;MGYG000004757_00433;MGYG000001604_00090;MGYG000003172_00938;MGYG000003252_01528 domain d__Bacteria 1.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,4AMYK@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 0.9696969696969697 H 0.9696969696969697 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 0.9696969696969697 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 0.9696969696969697 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003535_01089 0.030303030303030304 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2633387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2526929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)NDFSNTTR MGYG000003363_02700 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900766195|m__MGYG000003363 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003363_02700 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1129287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)NLDNVSENTSSAESR MGYG000000271_01499 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_01499 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 883455 4167058 0 3148307 988994 0 1639163 615479 1237367 0 0 0 928314 0 0 0 0 843585 0 685940 0 0 1366641 0 0 893297 0 1578858 0 0 0 2986234 0 0 0 0 4397092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 543914 0 0 0 0 0 0 0 0 0 0 0 0 0 396871 0 0 0 0 0 0 0 0 0 964592 0 0 0 0 0 0 0 181942 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)PIQVR MGYG000002105_00006 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__SFJ001|s__SFJ001 sp004555865|m__MGYG000002105 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000002105_00006 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4326623 0 0 0 9946870 0 0 0 6636017 0 0 0 0 0 0 0 0 0 0 0 7830273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)QAHIDAGAK MGYG000002999_00356;MGYG000002540_02142;MGYG000000375_01483;MGYG000001311_02933;MGYG000003012_02911;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000000205_02269;MGYG000003695_01114;MGYG000000145_03615;MGYG000002445_01920;MGYG000000193_03247;MGYG000002944_01470;MGYG000003110_00098;MGYG000004809_00788;MGYG000004799_00704;MGYG000000002_02120;MGYG000001065_01088;MGYG000002946_02881;MGYG000002966_00075;MGYG000002131_02428;MGYG000000242_02076;MGYG000003335_00316;MGYG000000233_00345;MGYG000001577_01888;MGYG000000099_02094;MGYG000003702_00925;MGYG000000252_01324;MGYG000000365_00999;MGYG000000301_01012;MGYG000004087_02290;MGYG000000312_01508;MGYG000001688_03910;MGYG000002972_00451;MGYG000000423_01499;MGYG000002857_01020;MGYG000002212_00259;MGYG000004296_01958;MGYG000000213_00374;MGYG000000281_02732;MGYG000000179_02084;MGYG000000142_01979;MGYG000000263_01341;MGYG000002095_00148;MGYG000004411_00321;MGYG000000806_01930;MGYG000001505_01467;MGYG000000212_01474;MGYG000001661_02632;MGYG000004785_01017;MGYG000000171_00850;MGYG000001757_00726;MGYG000001338_02547;MGYG000001602_01805;MGYG000003074_01265;MGYG000000133_02283;MGYG000002298_02410;MGYG000004246_01300;MGYG000001315_01699;MGYG000002035_01208 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.47540983606557374 186801|Clostridia 0.8852459016393442 C 0.7704918032786885 Psort location Cytoplasmic, score 0.47540983606557374 gap 0.9672131147540983 - 0.9672131147540983 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002999_00356 0.01639344262295082 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 595502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)QAHINAGAK MGYG000003457_01802;MGYG000000188_00829;MGYG000004740_01468;MGYG000002947_01132;MGYG000000325_00586;MGYG000000187_02264;MGYG000000262_01195;MGYG000004681_01193;MGYG000002775_01122;MGYG000000802_01543;MGYG000004707_01697;MGYG000001456.1_00715;MGYG000002278_02184;MGYG000002968_00328;MGYG000000562_01218;MGYG000000515_01608;MGYG000003274_01603;MGYG000002970_00369;MGYG000004317_00142;MGYG000001718_00619;MGYG000004396_00612;MGYG000001567_00998;MGYG000004593_01977;MGYG000000077_00219;MGYG000001334_01647 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CUJP@84998|Coriobacteriia 0.44 186801|Clostridia 0.48 C 0.76 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.56 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003457_01802 0.04 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341180 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)QEALGMVETR MGYG000000212_01004;MGYG000003012_02042;MGYG000004733_01677;MGYG000000301_01355;MGYG000000268_01896;MGYG000000252_02290;MGYG000000201_01077;MGYG000004039_01859;MGYG000002966_00344;MGYG000000031_02920;MGYG000000171_01277;MGYG000000263_00749;MGYG000001615_02630;MGYG000000127_01924;MGYG000002298_00042;MGYG000004785_00406;MGYG000000806_00431;MGYG000002298_02777;MGYG000000142_01603;MGYG000000202_01544 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.75 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.8 - 1.0 - 1.0 - 1.0 - 0.95 - 1.0 - 1.0 - 1.0 - 1.0 - 0.95 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01004 0.05 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 0.95 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2971993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)QIEETTSDFDREK MGYG000000038_02089;MGYG000002992_01078;MGYG000002445_00865;MGYG000001367_02937;MGYG000001607_00737;MGYG000001688_01574;MGYG000001617_04641;MGYG000002202_00450;MGYG000002279_00394 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,21YIV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000038_02089 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1725136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)QIETTTSDYDREK MGYG000004726_00851;MGYG000004464_01712 domain d__Bacteria 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2681F@186813|unclassified Clostridiales 0.5 186801|Clostridia 0.5 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 0.5 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004726_00851 0.5 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1115889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1461608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)SFDAGQTTTGDLWGDEWK MGYG000003165_00389 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus|s__Coprococcus sp900548315|m__MGYG000003165 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003165_00389 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)SFEQPVETR MGYG000004797_02944 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_02944 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K01802:E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]|K03770:ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] 1.0 none 1.0 1712730 0 0 0 3288098 2024107 0 0 0 0 0 0 3592472 0 0 3772479 0 1808986 0 0 0 1691208 1848017 2237149 0 0 0 1692671 0 0 0 0 0 0 0 1597570 1988733 0 4764298 0 0 0 2109437 1096940 3344070 0 0 0 0 0 4684446 4722516 0 2861626 0 1040071 1394713 0 0 1096797 1664614 874119 0 1059476 0 887109 0 0 0 0 0 0 0 1006881 3825095 0 1290839 0 0 0 2049821 1380004 1382506 0 0 0 0 0 2343270 1069038 0 1945508 0 2139539 746539 0 0 1168649 1522536 1031799 0 959195 0 1193034 0 0 0 0 0 0 0 1296685 1091314 0 0 0 0 0 0 0 0 0 0 0 0 0 959925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443182 0 0 0 0 0 0 0 0 0 0 1716392 0 0 0 3574882 1900320 1525768 0 0 0 0 0 4387458 1160387 0 2838245 0 3186372 1648230 0 0 1745022 2331393 1576024 0 2092280 0 2197634 0 0 0 0 0 0 0 1331366 2091640 0 +A(Ala->Ser)SGNDIVAPYADEFPGSTFVAGK MGYG000000236_00923 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AMNJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdh 1.0 GO:0005575,GO:0005623,GO:0009986,GO:0044464 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_00923 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 1.0 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1475114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2028382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)SLDVATDPWGIK MGYG000002279_00846;MGYG000000133_02658;MGYG000004719_00917;MGYG000000650_01797;MGYG000002298_02982;MGYG000002992_00180;MGYG000002212_01684;MGYG000000038_02902;MGYG000000002_03269;MGYG000000301_01961;MGYG000004733_03198;MGYG000003684_05093 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3XZEQ@572511|Blautia 0.5 186801|Clostridia 1.0 O 1.0 SPFH Band 7 PHB domain protein 0.5833333333333334 qmcA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Band_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_00846 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 698757 0 0 1248262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 805948 0 0 1022831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)SNIGQVAQFAAAGK MGYG000004482_01233;MGYG000002720_01300;MGYG000002753_00323;MGYG000002716_01693;MGYG000002042_01048;MGYG000003435_00255;MGYG000001616_01740;MGYG000002926_00914;MGYG000004628_00495;MGYG000000935_00193;MGYG000002794_00417;MGYG000002727_00774 domain d__Bacteria 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,2N72Y@216572|Oscillospiraceae 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 0.9166666666666666 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000004482_01233 0.08333333333333333 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 495506 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 800227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)STIFPEFVGHTFAVHDGR MGYG000002272_00455;MGYG000003899_00618;MGYG000004681_01721;MGYG000001300_02211;MGYG000002040_00974;MGYG000000195_02129;MGYG000000022_02036;MGYG000003166_00763;MGYG000002619_02382;MGYG000001627_01316;MGYG000002545_01136;MGYG000002274_00841;MGYG000002641_00984 domain d__Bacteria 1.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3WJ9F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA 1.0 rpsS 1.0 - 1.0 - 1.0 ko:K02965 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002272_00455 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02965:RP-S19, RSM19, rpsS; small subunit ribosomal protein S19 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277621 0 0 0 0 0 0 0 0 0 394392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174353 0 0 0 0 150386 0 0 0 0 87154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73695 0 0 0 0 0 0 0 0 0 204881 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)TGANTANEALGNLYIK MGYG000000042_01472;MGYG000001599_00128 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01472 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2894609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3602285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)TGWAEEDGTWVYYNR MGYG000001531_03141;MGYG000000179_05046;MGYG000001493_03216;MGYG000001531_03157;MGYG000000198_04292;MGYG000001493_03204;MGYG000001531_03144;MGYG000001493_03219 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 0.875 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001531_03141 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 418656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1281356 0 +A(Ala->Ser)TNVELIEAAC(Carbamidomethyl)GK MGYG000000038_01566 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena|m__MGYG000000038 1.0 COG0252@1|root,COG5275@1|root,COG0252@2|Bacteria,COG5275@2|Bacteria,1TQ9S@1239|Firmicutes,24A9Y@186801|Clostridia,27WDD@189330|Dorea 1.0 186801|Clostridia 1.0 EJ 1.0 Glycine/sarcosine/betaine reductase component B subunits 1.0 prdA 1.0 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114 1.0 1.21.4.1 1.0 ko:K10793 1.0 ko00330,map00330 1.0 - 1.0 R02825 1.0 RC00790 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_01566 1.0 D-proline reductase. - A pyruvoyl- and L-selenocysteine-containing enzyme found in a number of Clostridial species.-!-The pyruvoyl group, located on the PrdA subunit, binds the substrate, while the selenocysteine residue, located on the PrdB subunit, attacks the alpha-C-atom of D-proline, leading to a reductive cleavage of the C-N-bond of the pyrrolidine ring and formation of a selenoether.-!-The selenoether is cleaved by a cysteine residue of PrdB, resulting in a mixed selenide-sulfide bridge, which is restored to its reduced state by another selenocysteine protein, PrdC.-!-5-aminopentanoate is released from PrdA by hydrolysis, regenerating the pyruvoyl moiety.-!-The resulting mixed selenide-sulfide bridge in PrdC is reduced by NADH.-!-Formerly EC 1.4.1.6 and EC 1.4.4.1. 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine = [PrdC protein]-L-selenocysteine/L-cysteine + D-proline. 1.0 1.0 1.0 1.0 Arginine and proline metabolism 1.0 K10793:prdA; D-proline reductase (dithiol) PrdA [EC:1.21.4.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 2521800 3540059 2447957 0 0 0 0 0 0 0 3926898 0 0 0 0 0 0 3067481 0 0 0 0 0 2652558 0 0 2877909 0 0 0 0 0 3186725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3563000 0 0 0 0 0 3254860 0 0 573157 0 4289258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2832581 4761946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3767368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3621202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)TVVTGVEMFR MGYG000003868_01133;MGYG000003868_01166;MGYG000004769_00412;MGYG000004769_00437 genus d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4H22P@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003868_01133 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 205823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723119 0 0 793274 0 0 0 0 0 744120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)VDPSVAEEANK MGYG000000196_00570 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00570 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 988009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)VGEAIVEATK MGYG000000013_01224;MGYG000002549_02739;MGYG000002281_01909;MGYG000000138_00869;MGYG000000044_00323;MGYG000004876_02584;MGYG000002455_00199;MGYG000004185_02169 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 0.75 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_01224 0.125 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2081411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)VGELLQNQYR MGYG000002528_01103;MGYG000000142_00117;MGYG000004140_01870;MGYG000003063_00668;MGYG000002445_01331;MGYG000000179_00950;MGYG000000145_02776;MGYG000001814_01581;MGYG000004785_02035;MGYG000003694_02393;MGYG000000164_01118;MGYG000000271_03641;MGYG000000198_01125;MGYG000002148_02227;MGYG000000193_02077;MGYG000000909_01259;MGYG000000217_01477;MGYG000000359_01966;MGYG000000262_00025;MGYG000002492_00339;MGYG000002517_00197;MGYG000001707_01471;MGYG000002670_00359;MGYG000003422_00869;MGYG000000028_00231;MGYG000004697_01015;MGYG000000484_02056;MGYG000003427_01334;MGYG000000139_00682;MGYG000001338_03384;MGYG000001683_01328;MGYG000001619_01910;MGYG000000233_00817;MGYG000000242_00290;MGYG000000002_03604;MGYG000000127_00618;MGYG000002304_02205;MGYG000004414_00350;MGYG000004735_00902;MGYG000000150_02012;MGYG000002417_01250;MGYG000000172_05471;MGYG000003355_03484;MGYG000000018_00459;MGYG000000281_02099;MGYG000004271_02226;MGYG000000249_00042;MGYG000000398_01656;MGYG000003486_01060;MGYG000001493_02698;MGYG000001564_03092;MGYG000003684_05127;MGYG000002289_02137;MGYG000000251_01869;MGYG000004680_00150;MGYG000001311_05232;MGYG000002290_01341;MGYG000001615_01700;MGYG000000489_01681;MGYG000000278_00899;MGYG000001319_01769;MGYG000000690_00038;MGYG000002052_00237;MGYG000001310_01990;MGYG000004431_01386;MGYG000000213_01890 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia 0.2727272727272727 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 - 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01103 0.015151515151515152 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03043:rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 1673084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1178907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)VIELAGIK MGYG000001315_01353;MGYG000004733_00985;MGYG000000201_02098;MGYG000000252_01802;MGYG000001423_01155;MGYG000000301_00177;MGYG000001338_02790;MGYG000001689_02303;MGYG000000031_02249;MGYG000000142_02050;MGYG000000133_00062;MGYG000000002_00865;MGYG000002966_02558;MGYG000000212_03064;MGYG000000213_00197;MGYG000004296_00406;MGYG000000184_01189;MGYG000000050_01189;MGYG000000216_02346;MGYG000002298_00345;MGYG000000251_01814 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.9047619047619048 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01353 0.047619047619047616 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1842939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1020905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)VIELAGLK MGYG000001315_01353;MGYG000000133_00062;MGYG000001338_02790;MGYG000000142_02050 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.75 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01353 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1802984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)VIEMAGIK MGYG000000038_01593;MGYG000004842_00293;MGYG000000206_01051;MGYG000001374_01179;MGYG000000146_01034;MGYG000000164_02747;MGYG000002279_01055;MGYG000001303_01198;MGYG000001310_00104 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,27V4S@189330|Dorea 0.5555555555555556 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_01593 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1359013 0 0 0 0 0 0 0 0 0 0 631377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756527 0 0 951856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)VLDSYAGK MGYG000000039_02623;MGYG000000195_01938;MGYG000000022_00316 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,3WJGA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000039_02623 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1591982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 948727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)VSETVDIMDAK MGYG000002945_00739 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus massiliensis|m__MGYG000002945 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,27IGM@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein FAD-binding domain 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002945_00739 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 7081442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)VVELAGIK MGYG000000242_01806;MGYG000000359_02324;MGYG000003012_01983;MGYG000000413_00080;MGYG000000141_02164 domain d__Bacteria 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,21YA9@1506553|Lachnoclostridium 0.2 186801|Clostridia 0.8 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 0.8 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000242_01806 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1070403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)WAPQNWDKYDELIK MGYG000000404_01511 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA11774|s__UBA11774 sp003507655|m__MGYG000000404 1.0 COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Family 5 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000404_01511 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 2938480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)YADMMEPIYK MGYG000004479_01906;MGYG000001783_02108;MGYG000003693_03030;MGYG000001306_00956 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2825@1|root,COG2825@2|Bacteria,4NWPA@976|Bacteroidetes,2G3DE@200643|Bacteroidia,4AWDW@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 M 1.0 Membrane 0.75 - 0.75 - 1.0 - 1.0 ko:K06142 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 OmpH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004479_01906 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06142:hlpA, ompH; outer membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1123922 0 0 0 0 0 0 0 0 0 0 0 0 0 1319706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1602278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525139 0 510877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)YALLDELKK MGYG000001607_01352 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_B|s__Dorea_B phocaeensis|m__MGYG000001607 1.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia,27V62@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) 1.0 proS 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 6.1.1.15 1.0 ko:K01881 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03661 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,ProRS-C_1,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000001607_01352 1.0 proline--tRNA ligase. prolyl-tRNA synthetase. - ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01881:PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15] 1.0 none 1.0 0 0 0 511262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)YDGQYVQTR MGYG000002293_00403 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG1629@1|root,COG4771@2|Bacteria,4NIXB@976|Bacteroidetes,2FNC3@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 beta-fructofuranosidase activity 1.0 scrL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_32C,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00403 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3016255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)YILAPDGLK MGYG000004869_03323 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lactonifactor|s__Lactonifactor sp009677585|m__MGYG000004869 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3XZ12@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004869_03323 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1120084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)YIPGIGHNLQEHSVVLIR MGYG000002113_00819 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Anaerovibrio|s__Anaerovibrio sp900548165|m__MGYG000002113 1.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4H4CG@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit 1.0 rpsL 1.0 - 1.0 - 1.0 ko:K02950 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S12_S23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002113_00819 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02950:RP-S12, MRPS12, rpsL; small subunit ribosomal protein S12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 804966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)YSPWSSK MGYG000002438_00414 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG3630@1|root,COG3630@2|Bacteria,4NIHN@976|Bacteroidetes,2FMSV@200643|Bacteroidia,22W1S@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxaloacetate decarboxylase, gamma chain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 LTD,OAD_gamma 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00414 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1222051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)YTPQEISAMILQK MGYG000001733_01226 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550615|m__MGYG000001733 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,2N6EU@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 O 1.0 MreB/Mbl protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001733_01226 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 771973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Ser)YTVETNR MGYG000000196_04774 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia,4AMCZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04774 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 895898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656174 0 0 +A(Ala->Thr)AAEAYFGK MGYG000000196_01844;MGYG000000029_02657;MGYG000003312_02145;MGYG000001345_04496 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_01844 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1399864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)AAESYLSK MGYG000003367_01391;MGYG000004876_01285 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003367_01391 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1911619 0 0 2474203 0 1143339 0 2299759 0 0 0 0 2648421 3284344 0 0 2354301 0 0 0 0 0 0 0 0 0 0 0 0 4434269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6316477 0 3629733 0 3390012 4536151 3727103 4226813 0 2991729 0 0 0 0 3814793 0 1913448 0 0 0 0 0 0 0 0 0 0 0 2650366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2050119 0 0 0 0 0 0 1724844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3024391 0 0 0 2791338 0 0 0 2327616 +A(Ala->Thr)AAEVTPEEKKEE MGYG000000271_02066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,27IMH@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Fibronectin type III-like domain 1.0 - 1.0 - 1.0 3.2.1.21 1.0 ko:K05349 1.0 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 1.0 - 1.0 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 1.0 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH3 1.0 - 1.0 Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C 1.0 - 1.0 GH3 1.0 GH3 1.0 GH3 1.0 MGYG000000271_02066 1.0 beta-glucosidase. gentobiase. Wide specificity for beta-D-glucosides.-!-Some examples also hydrolyze one or more of the following: beta-D- galactosides, alpha-L-arabinosides, beta-D-xylosides and beta-D- fucosides. Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose. 1.0 1.0 1.0 1.0 Cyanoamino acid metabolism|Starch and sucrose metabolism|Phenylpropanoid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K05349:bglX; beta-glucosidase [EC:3.2.1.21] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 97236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2469811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)AAQTDNVHRPFYPMLIFR MGYG000002469_00856 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium breve|m__MGYG000002469 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002469_00856 1.0 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K01621:xfp, xpk; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)AASESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3420558 0 2230228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5931805 0 0 8532388 0 0 0 6360862 0 0 0 0 0 0 0 8717928 0 0 0 0 0 0 0 0 0 0 0 0 1623647 0 0 1527232 0 0 0 0 2160865 0 0 0 0 1799405 0 0 0 0 0 0 0 0 6702418 0 0 0 0 0 0 0 0 0 0 0 0 1780388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521019 0 0 0 0 0 0 0 0 0 848364 0 0 727932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660281 699352 0 +A(Ala->Thr)AASESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 871387 0 0 0 0 0 0 0 0 0 0 0 0 698258 0 0 0 0 0 0 0 0 0 0 0 0 0 811392 888669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)AASESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004884_01637 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 1191884 0 0 0 0 0 0 0 1021672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 833801 0 0 0 0 948492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)AEAYFLLAEAK MGYG000002478_01404;MGYG000004797_04332 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01404 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1735704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)AEIPEAIR MGYG000000136_02061;MGYG000002670_00403;MGYG000001315_01353;MGYG000002234_01458;MGYG000004733_00985;MGYG000003891_01006;MGYG000000252_01802;MGYG000000280_01284;MGYG000000031_02249;MGYG000000142_02050;MGYG000004630_00952;MGYG000002492_00392;MGYG000000135_01188;MGYG000000690_01576;MGYG000000028_01605;MGYG000004689_01598;MGYG000002517_02856;MGYG000000002_00865;MGYG000002966_02558;MGYG000001186_01095;MGYG000000213_00197;MGYG000004296_00406;MGYG000000806_01299;MGYG000002278_02309;MGYG000000050_01189;MGYG000002298_00345;MGYG000000193_02113;MGYG000000201_02098;MGYG000000301_00177;MGYG000004879_01580;MGYG000001338_02790;MGYG000002528_01856;MGYG000000164_02747;MGYG000001689_02303;MGYG000000562_01931;MGYG000000133_00062;MGYG000000212_03064;MGYG000000184_01189;MGYG000003694_02445;MGYG000000216_02346;MGYG000000251_01814;MGYG000001637_00014;MGYG000000187_01741 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.46511627906976744 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000136_02061 0.023255813953488372 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2171422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)AGVIVAC(Carbamidomethyl)DTNVPTDRFDGK MGYG000002492_00017 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Phosphotransferase System 1.0 fruA 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 GGDEF,PTS_EIIA_2,PTS_EIIC,PTS_IIB,Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00017 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Phosphotransferase system (PTS) 1.0 K02768:fruB; fructose PTS system EIIA component [EC:2.7.1.202]|K02769:fruAb; fructose PTS system EIIB component [EC:2.7.1.202]|K02770:fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2599405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2673789 0 0 0 0 2580781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)AGVIVAC(Carbamidomethyl)DTNVPTDRFDGKK MGYG000002492_00017 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Phosphotransferase System 1.0 fruA 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 GGDEF,PTS_EIIA_2,PTS_EIIC,PTS_IIB,Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00017 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Phosphotransferase system (PTS) 1.0 K02768:fruB; fructose PTS system EIIA component [EC:2.7.1.202]|K02769:fruAb; fructose PTS system EIIB component [EC:2.7.1.202]|K02770:fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193983 0 0 0 0 349274 0 0 314691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 377303 0 0 0 0 625789 0 0 2758920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3495911 0 0 0 0 2961558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155871 +A(Ala->Thr)ANVSLVGYEK MGYG000004087_00692;MGYG000001564_03645;MGYG000000205_00403;MGYG000000198_03144 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 0.75 186801|Clostridia 0.75 CQ 1.0 PFAM microcompartments protein 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004087_00692 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 9341003 0 0 0 0 0 0 0 0 0 0 0 15318127 0 0 0 0 0 0 0 12321948 0 0 0 0 0 14527780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25466540 0 0 0 0 17282713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81291414 0 0 0 0 0 0 37020253 0 0 0 0 0 0 0 0 0 0 0 0 29458752 0 32629206 0 0 0 0 0 0 0 31240089 0 0 55223525 +A(Ala->Thr)APHLDGSYAAFGK MGYG000000133_02803;MGYG000000301_01800 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides 1.0 ppiB 1.0 - 1.0 5.2.1.8 1.0 ko:K03768 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Pro_isomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02803 0.5 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K03768:PPIB, ppiB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1211434 0 0 0 0 0 0 0 0 0 0 0 1473779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)AVAGIK MGYG000004317_00074 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp900316325|m__MGYG000004317 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,268N0@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000004317_00074 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)AVVGDTVGDPFK MGYG000003510_01564;MGYG000002964_00576;MGYG000002036_00419;MGYG000001500_00249;MGYG000002212_02487;MGYG000002673_01165;MGYG000001502_01055;MGYG000000179_01304;MGYG000000198_01375;MGYG000002727_01191;MGYG000001576_02602;MGYG000002953_01954;MGYG000002229_02459;MGYG000001616_01732;MGYG000003589_01348 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,2N6F3@216572|Oscillospiraceae 0.5333333333333333 186801|Clostridia 1.0 C 1.0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane 0.8666666666666667 hppA 1.0 - 1.0 3.6.1.1 1.0 ko:K15987 1.0 ko00190,map00190 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 3.A.10.1 1.0 - 1.0 - 1.0 H_PPase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003510_01564 0.06666666666666667 inorganic diphosphatase. pyrophosphate phosphohydrolase. Specificity varies with the source and with the activating metal ion.-!-The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9. cf. EC 7.1.3.1. diphosphate + H2O = H(+) + 2 phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation 1.0 K15987:hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1187103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)DAPVAGK MGYG000002506_00491;MGYG000002323_02391;MGYG000000093_04195 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2376@1|root,COG2376@2|Bacteria,1MVSR@1224|Proteobacteria,1RNRQ@1236|Gammaproteobacteria,3XP0J@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 1.0 G 1.0 Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for the phosphoenolpyruvate (PEP)- dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP. Binds covalently dihydroxyacetone in hemiaminal linkage. DhaK acts also as corepressor of the transcription activator DhaR by binding to the sensor domain of DhaR. In the presence of dihydroxyacetone, DhaL-ADP displaces DhaK and stimulates DhaR activity. In the absence of dihydroxyacetone, DhaL-ADP is converted by the PTS to DhaL-ATP, which does not bind to DhaR 0.6666666666666666 dhaK 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019637,GO:0019751,GO:0033554,GO:0034308,GO:0042180,GO:0042182,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0047324,GO:0050896,GO:0051716,GO:0061610,GO:0071704,GO:1901135,GO:1901575,GO:1901615 1.0 2.7.1.121 1.0 ko:K05878 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcHS_1320.EcHS_A1304,iUMNK88_1353.UMNK88_1515,iYL1228.KPN_03495 1.0 Dak1,Dak2 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00491 0.3333333333333333 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways 1.0 K05878:dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] 1.0 none 1.0 0 0 0 0 0 0 0 82293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258575 0 0 0 0 0 0 0 0 118676 0 143092 0 0 0 0 0 0 0 0 0 598149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541750 421163 551141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1354999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1582372 0 0 0 0 0 0 0 0 2967112 2370534 1189265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)EGVDLSGDKMAMQR MGYG000000153_02121 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-45|s__CAG-45 sp000438375|m__MGYG000000153 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000153_02121 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1341226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)GDAAAALK MGYG000002478_02340 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02340 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9258451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)GDDAAGLSISEK MGYG000001309_02256;MGYG000004879_00388;MGYG000001309_02255;MGYG000003116_00184;MGYG000004317_00523;MGYG000003142_01387;MGYG000003273_00970;MGYG000003142_01386 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,36ED6@31979|Clostridiaceae 0.75 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 fliC 0.75 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_IN,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001309_02256 0.125 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 1733369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1561404 0 3917645 0 0 0 0 4696930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)GGSIISSQK MGYG000001364_02798;MGYG000000243_01847;MGYG000001783_02406 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001364_02798 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03072:secD; preprotein translocase subunit SecD|K12257:secDF; SecD/SecF fusion protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1586009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)GLDKIISQIK MGYG000000198_04354 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG1390@1|root,COG1390@2|Bacteria,1VDHZ@1239|Firmicutes,24H5N@186801|Clostridia,220QV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane 1.0 atpE 1.0 - 1.0 - 1.0 ko:K02121 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 vATP-synt_E 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04354 1.0 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways 1.0 K02121:ATPVE, ntpE, atpE; V/A-type H+/Na+-transporting ATPase subunit E 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2224812 0 0 0 0 2654682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3708117 0 0 0 0 0 0 3457662 0 0 0 0 132028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365106 0 0 0 0 2698339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)GMIGLAK MGYG000000074_00315;MGYG000004797_02999;MGYG000000243_00655;MGYG000004763_02028;MGYG000002438_03088 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1028@1|root,COG1028@2|Bacteria,4NEAI@976|Bacteroidetes,2FNB4@200643|Bacteroidia,4ANUZ@815|Bacteroidaceae 0.6 976|Bacteroidetes 1.0 IQ 1.0 with different specificities (related to short-chain alcohol 0.6 fabG 1.0 - 1.0 1.1.1.100 1.0 ko:K00059 1.0 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 1.0 M00083,M00572 1.0 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00315 0.2 3-oxoacyl-[acyl-carrier-protein] reductase. - Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates. a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis|Prodigiosin biosynthesis|Biotin metabolism|Biosynthesis of unsaturated fatty acids|Metabolic pathways|Fatty acid metabolism 1.0 K00059:fabG, OAR1; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)GTVTMDVTK MGYG000000139_00679;MGYG000002992_01641;MGYG000000217_01483;MGYG000000095_03286;MGYG000002963_02025;MGYG000001698_00708;MGYG000004839_01328;MGYG000000171_01515;MGYG000003694_02390;MGYG000000201_02339;MGYG000004762_01114;MGYG000000050_01365;MGYG000004733_01323;MGYG000001027_00236;MGYG000000179_05050;MGYG000003695_01274;MGYG000000152_04608;MGYG000000242_00769;MGYG000000119_02509;MGYG000001571_03428;MGYG000000076_03547;MGYG000002966_01277;MGYG000000251_00050;MGYG000000249_00046;MGYG000004296_01660;MGYG000001338_03534;MGYG000000387_00298;MGYG000000154_02173;MGYG000001970_02771;MGYG000000212_02414;MGYG000002552_01596;MGYG000001622_01986;MGYG000003425_04472;MGYG000001186_01608;MGYG000004604_00078;MGYG000001714_01227;MGYG000000087_02073;MGYG000004735_02574;MGYG000000268_01636;MGYG000002445_02953;MGYG000002772_00853;MGYG000001303_01960;MGYG000004630_01085;MGYG000001607_01030;MGYG000001687_02063;MGYG000001315_01189;MGYG000002517_00192;MGYG000002286_02461;MGYG000004718_01623;MGYG000000146_01144;MGYG000001748_00537;MGYG000002202_02038;MGYG000000271_03296;MGYG000000164_01129;MGYG000000031_00709;MGYG000000153_01114;MGYG000002845_01899;MGYG000000136_02022;MGYG000001689_01643;MGYG000002170_01019;MGYG000001065_00817;MGYG000003335_00786;MGYG000002393_01693;MGYG000000278_00573;MGYG000001439_02403;MGYG000002492_00336;MGYG000004519_00684;MGYG000001374_02225;MGYG000001319_01772;MGYG000002298_02666;MGYG000000287_00086;MGYG000000078_01689;MGYG000003149_00722;MGYG000002670_00356;MGYG000000002_03534;MGYG000000198_05828;MGYG000000364_02037;MGYG000001660_01137;MGYG000002596_02351;MGYG000001683_01776;MGYG000004747_01843;MGYG000000080_02021;MGYG000003702_00729;MGYG000002279_01914;MGYG000001688_00640;MGYG000002312_03039;MGYG000000142_01261;MGYG000000562_01874;MGYG000002836_02018;MGYG000000187_02021;MGYG000002985_00771;MGYG000000489_01684;MGYG000002835_01623;MGYG000000018_02173;MGYG000000140_01578;MGYG000000205_00361;MGYG000000274_00236;MGYG000000200_03209;MGYG000001141_02451;MGYG000001379_00716;MGYG000003215_01171;MGYG000000133_01992;MGYG000004087_00328;MGYG000000252_00576 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 0.36538461538461536 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000139_00679 0.009615384615384616 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 1474687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3241875 0 0 0 0 0 0 0 0 0 743243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1102867 0 0 0 0 0 0 0 0 525223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)HGLDKDFK MGYG000002281_00379;MGYG000001313_01603;MGYG000001783_00231;MGYG000003693_02561;MGYG000001378_00884;MGYG000003681_01596;MGYG000000196_04607;MGYG000004797_00652;MGYG000004876_02961;MGYG000001787_00293 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,2FN9P@200643|Bacteroidia,4AN2N@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 xylA 1.0 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 1.0 5.3.1.5 1.0 ko:K01805 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 - 1.0 R00878,R01432 1.0 RC00376,RC00516 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_00379 0.1 xylose isomerase. D-xylose ketol-isomerase. Contains two divalent metal ions, preferably magnesium, located at different metal-binding sites within the active site.-!-The enzyme catalyzes the interconversion of aldose and ketose sugars with broad substrate specificity.-!-The enzyme binds the closed form of its sugar substrate (in the case of xylose and glucose, only the alpha anomer) and catalyzes ring opening to generate a form of open-chain conformation that is coordinated to one of the metal sites.-!-Isomerization proceeds via a hydride-shift mechanism. alpha-D-xylose = alpha-D-xylulofuranose. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K01805:xylA; xylose isomerase [EC:5.3.1.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2333533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)IDMIGMPGMK MGYG000000164_01756;MGYG000002279_02008;MGYG000001315_01946;MGYG000002992_01235;MGYG000000038_01290;MGYG000002945_01470;MGYG000001687_01112 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,27VFG@189330|Dorea 0.8571428571428571 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000164_01756 0.14285714285714285 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 888155 0 0 894179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)IGQFQNTQFQLADMATK MGYG000000204_00801 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eubacterium_G|s__Eubacterium_G sp000435815|m__MGYG000000204 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000204_00801 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1105048 0 0 0 0 0 0 0 0 +A(Ala->Thr)IIDSLHEFNPMMGHR MGYG000000140_01464;MGYG000001687_00537;MGYG000004558_03187;MGYG000004735_00207;MGYG000000249_01089;MGYG000000728_00587;MGYG000000164_00358;MGYG000001607_01964;MGYG000000159_02392;MGYG000001439_01567;MGYG000001374_00487;MGYG000001310_01399;MGYG000001637_01169;MGYG000004296_00104 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.6428571428571429 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8571428571428571 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000140_01464 0.07142857142857142 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)IIEAIK MGYG000002966_01860 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900551075|m__MGYG000002966 1.0 COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 COG NOG14451 non supervised orthologous group 1.0 - 1.0 - 1.0 2.7.4.25 1.0 ko:K00945 1.0 ko00240,ko01100,map00240,map01100 1.0 M00052 1.0 R00158,R00512,R01665 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002966_01860 1.0 (d)CMP kinase. deoxycytidylate kinase. The prokaryotic cytidine monophosphate kinase specifically phosphorylates CMP (or dCMP), using ATP as the preferred phosphoryl donor.-!-Unlike EC 2.7.4.14, a eukaryotic enzyme that phosphorylates UMP and CMP with similar efficiency, the prokaryotic enzyme phosphorylates UMP with very low rates, and this function is catalyzed in prokaryotes by EC 2.7.4.22.-!-The enzyme phosphorylates dCMP nearly as well as it does CMP. (1) ATP + CMP = ADP + CDP. (2) ATP + dCMP = ADP + dCDP. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00945:cmk; CMP/dCMP kinase [EC:2.7.4.25] 1.0 none 1.0 0 0 0 0 0 0 0 957389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)ILDALK MGYG000000255_00877;MGYG000000233_02976 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,21XUU@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 COG COG1775 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit, BcrC BadD HgdB 1.0 hgdB 1.0 - 1.0 1.3.7.8,4.2.1.167 1.0 ko:K04112,ko:K20904 1.0 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 1.0 M00541 1.0 R02451 1.0 RC00002,RC01839 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HGD-D 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_00877 0.5 benzoyl-CoA reductase. | (R)-2-hydroxyglutaryl-CoA dehydratase. - Inactive toward aromatic acids that are not CoA esters but will also catalyze the reaction: NH3 + acceptor + 2 ADP + 2 phosphate = hydroxylamine + reduced acceptor + 2 ATP + H2O.-!-In the presence of reduced acceptor, but in the absence of oxidizable substrate, the enzyme catalyzes the hydrolysis of ATP to ADP plus phosphate.-!-Formerly EC 1.3.99.15. | The enzymes from the bacteria Acidaminococcus fermentans and Clostridium symbiosum are involved in the fermentation of L-glutamate.-!-The enzyme contains [4Fe-4S] clusters, FMNH2 and riboflavin.-!-It must be activated by a an activator protein.-!-Once activated, it can catalyze many turnovers. 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized 2[4Fe-4S]- [ferredoxin] + 2 phosphate = 2 ATP + benzoyl-CoA + 2 H2O + reduced 2[4Fe- 4S]-[ferredoxin]. | (R)-2-hydroxyglutaryl-CoA = (2E)-glutaconyl-CoA + H2O. 1.0 1.0 1.0 1.0 Benzoate degradation|Metabolic pathways|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04112:bcrC, badD; benzoyl-CoA reductase subunit C [EC:1.3.7.8]|K20904:hgdB; (R)-2-hydroxyglutaryl-CoA dehydratase subunit beta [EC:4.2.1.167] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1576867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)ILEALK MGYG000001319_00393;MGYG000000089_01318 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,4BZXW@830|Butyrivibrio 0.5 186801|Clostridia 1.0 G 1.0 PTS HPr component phosphorylation site 0.5 - 0.5 - 1.0 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 1.0 - 1.0 - 0.5 PTS-HPr 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001319_00393 0.5 - - - - 0.5 0.5 0.5 0.5 - 0.5 - 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 968163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 95632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)KIDAAVDTK MGYG000004899_00435 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900555635|m__MGYG000004899 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004899_00435 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)KLEAEGAEVNLK MGYG000000164_01127 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,27VNP@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_01127 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 207809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117598 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)LAALNAGLK MGYG000000022_00458;MGYG000000039_00979;MGYG000000589_00366 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00458 0.3333333333333333 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1719481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1336171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1996646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)LAANLKEGK MGYG000002545_01058 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_G|m__MGYG000002545 1.0 COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,3WIE3@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002545_01058 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1014233 0 0 0 0 71512 0 0 0 0 65867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)LAIC(Carbamidomethyl)TVSDHIR MGYG000002507_00236;MGYG000002323_00590 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0813@1|root,COG0813@2|Bacteria,1MUW6@1224|Proteobacteria,1RMMA@1236|Gammaproteobacteria,3WWYQ@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Phosphorylase superfamily 1.0 deoD 1.0 GO:0003674,GO:0003824,GO:0004731,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006152,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009164,GO:0009987,GO:0015949,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0019686,GO:0033554,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658 1.0 2.4.2.1 1.0 ko:K03784 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_1997,iB21_1397.B21_04226,iE2348C_1286.E2348C_4682,iEC042_1314.EC042_4881,iECABU_c1320.ECABU_c50190,iECBD_1354.ECBD_3636,iECB_1328.ECB_04260,iECD_1391.ECD_04260,iECED1_1282.ECED1_5255,iECIAI39_1322.ECIAI39_4916,iECNA114_1301.ECNA114_4626,iECO26_1355.ECO26_5590,iECOK1_1307.ECOK1_4950,iECP_1309.ECP_4768,iEcolC_1368.EcolC_3672,iLF82_1304.LF82_0467,iNRG857_1313.NRG857_22170,iPC815.YPO0440,iSFV_1184.SFV_4418,iSF_1195.SF4416,iSFxv_1172.SFxv_4809,iS_1188.S4687,iUMN146_1321.UM146_22680,iUMNK88_1353.UMNK88_5303,iUTI89_1310.UTI89_C5155,ic_1306.c5468 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002507_00236 0.5 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Nicotinate and nicotinamide metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K03784:deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1834418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)LGDLSEEEFEAHK MGYG000000133_00919 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) 1.0 galK 1.0 - 1.0 2.7.1.6 1.0 ko:K00849 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00554,M00632 1.0 R01092 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00919 1.0 galactokinase. - Part of the Leloir pathway for galactose metabolism.-!-The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine. alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+). 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K00849:galK; galactokinase [EC:2.7.1.6] 1.0 none 1.0 0 0 107132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212558 0 0 0 0 0 0 0 0 0 0 0 0 0 566086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1067229 0 0 0 0 0 0 0 764655 0 0 1430536 0 0 0 0 913390 0 0 0 0 0 0 0 0 0 0 0 0 0 1290476 0 0 0 0 688912 +A(Ala->Thr)LLHNMVVGVTDGYKK MGYG000004482_01002 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4|s__ER4 sp900546295|m__MGYG000004482 1.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,2N726@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center 1.0 rplF 1.0 - 1.0 - 1.0 ko:K02933 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004482_01002 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02933:RP-L6, MRPL6, rplF; large subunit ribosomal protein L6 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 868997 0 0 0 0 0 0 0 444913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)LTLYGK MGYG000001346_01584 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1256@1|root,COG1256@2|Bacteria,4PKVX@976|Bacteroidetes,2G05N@200643|Bacteroidia,4AWF1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 bacterial-type flagellum assembly 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_01584 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8322197 2618057 0 0 0 1557675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)MEPSR MGYG000000133_00153 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3XZ1Q@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 Psort location Cytoplasmic, score 8.87 1.0 purB 1.0 - 1.0 4.3.2.2 1.0 ko:K01756 1.0 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 1.0 M00048,M00049 1.0 R01083,R04559 1.0 RC00379,RC00444,RC00445 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADSL_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000000133_00153 1.0 adenylosuccinate lyase. succino AMP-lyase. Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole. (1) N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate. (2) (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamide + fumarate. 1.0 1.0 1.0 1.0 Purine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01756:purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1600694 0 0 +A(Ala->Thr)MGQQITSDAC(Carbamidomethyl)THDNAEEK MGYG000001319_02248 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia,4BYAS@830|Butyrivibrio 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001319_02248 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K15770:cycB, ganO, mdxE; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16689706 0 0 0 0 32194250 0 0 0 0 37061798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)NEAYLQGQLGNPK MGYG000002506_02522;MGYG000000235_01782;MGYG000002515_02771 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0191@1|root,COG0191@2|Bacteria,1MURX@1224|Proteobacteria,1RQUC@1236|Gammaproteobacteria,3XMVJ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis 1.0 fbaA 1.0 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iZ_1308.Z4263 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02522 0.3333333333333333 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1086185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 565107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)NELKADEER MGYG000002323_01056 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia sp000208585|m__MGYG000002323 1.0 COG0544@1|root,COG0544@2|Bacteria,1MUJP@1224|Proteobacteria,1RNZE@1236|Gammaproteobacteria,3XM6A@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_01056 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2957137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)NLIAQLTAPVR MGYG000001489_02989;MGYG000000003_02000;MGYG000000138_01885;MGYG000004658_00545;MGYG000000355_01595;MGYG000002033_00373;MGYG000004006_02257;MGYG000003701_02224;MGYG000004536_00884;MGYG000002007_01308;MGYG000000415_01725;MGYG000003926_01411;MGYG000000222_01291;MGYG000000174_04029;MGYG000000074_01416;MGYG000002218_02809;MGYG000001302.1_01294;MGYG000003539_00735;MGYG000000053_01501;MGYG000002203_00959;MGYG000002082_00141 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0331@1|root,COG0331@2|Bacteria,4NE1D@976|Bacteroidetes,2FM9P@200643|Bacteroidia,22U7E@171550|Rikenellaceae 0.5238095238095238 976|Bacteroidetes 0.9523809523809523 I 0.8571428571428571 malonyl CoA-acyl carrier protein transacylase 0.8571428571428571 fabD 0.8571428571428571 - 1.0 2.3.1.39 0.8571428571428571 ko:K00645 0.8571428571428571 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 0.8571428571428571 M00082 0.8571428571428571 R01626,R11671 0.8571428571428571 RC00004,RC00039,RC02727 0.8571428571428571 ko00000,ko00001,ko00002,ko01000,ko01004 0.8571428571428571 - 1.0 - 1.0 - 1.0 Acyl_transf_1 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001489_02989 0.047619047619047616 [acyl-carrier-protein] S-malonyltransferase. MCAT. Essential, along with EC 2.3.1.38, for the initiation of fatty-acid biosynthesis in bacteria.-!-Also provides the malonyl groups for polyketide biosynthesis.-!-The product of the reaction, malonyl-ACP, is an elongation substrate in fatty-acid biosynthesis.-!-In Mycobacterium tuberculosis, holo-ACP (the product of EC 2.7.8.7) is the preferred substrate.-!-This enzyme also forms part of the multienzyme complexes EC 4.1.1.88 and EC 4.1.1.89.-!-Malonylation of ACP is immediately followed by decarboxylation within the malonate-decarboxylase complex to yield acetyl-ACP, the catalytically active species of the decarboxylase.-!-In the enzyme from Klebsiella pneumoniae, methylmalonyl-CoA can also act as a substrate but acetyl-CoA cannot whereas the enzyme from Pseudomonas putida can use both as substrates.-!-The ACP subunit found in fatty-acid biosynthesis contains a pantetheine-4'-phosphate cofactor; that from malonate decarboxylase also contains pantetheine-4'-phosphate but in the form of a 2'-(5-triphosphoribosyl)-3'-dephospho-CoA cofactor. holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]. 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 Fatty acid biosynthesis|Prodigiosin biosynthesis|Metabolic pathways|Fatty acid metabolism 0.8571428571428571 K00645:fabD, MCAT, MCT1; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] 0.8571428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1681023 0 0 0 0 0 0 0 0 +A(Ala->Thr)NVDNVVENTTSAESR MGYG000000136_01850 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp000434275|m__MGYG000000136 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000136_01850 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 800756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)QLSYTAK MGYG000002478_00307 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,4NZZK@976|Bacteroidetes,2FX99@200643|Bacteroidia,4AV66@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Outer membrane protein beta-barrel family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,OMP_b-brl_3,Plug 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00307 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 5495842 6118075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6038747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)SEDTALR MGYG000002517_02764 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia 1.0 186801|Clostridia 1.0 GK 1.0 ROK family 1.0 - 1.0 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02764 1.0 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Galactose metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Neomycin, kanamycin and gentamicin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00845:glk; glucokinase [EC:2.7.1.2] 1.0 none 1.0 0 0 422049 0 0 151996 0 0 0 521042 0 0 0 0 0 0 0 0 0 0 0 735252 0 116060 493367 0 0 0 0 0 0 0 285338 0 0 0 0 266025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314189 0 0 0 0 0 0 0 0 0 0 0 0 357769 0 0 334801 0 0 322004 0 0 0 143394 0 0 0 0 0 0 0 0 0 0 0 889859 0 512396 326044 0 0 0 0 0 0 0 231616 0 0 0 0 450326 0 0 624680 0 0 860161 0 0 0 1547639 0 0 0 0 0 0 0 0 0 0 0 598117 0 1090858 2793961 0 0 0 0 0 0 0 1107841 0 0 0 0 899181 0 0 1559735 0 0 1730009 0 0 0 2318996 0 0 0 0 0 0 0 0 0 0 0 1050123 0 1984111 2598373 0 0 0 0 0 0 0 1871926 0 0 0 0 2071519 +A(Ala->Thr)TDLNAQELGK MGYG000002478_03813 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG2731@1|root,COG2731@2|Bacteria,4P2HG@976|Bacteroidetes,2G2E3@200643|Bacteroidia,4AVXE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Domain of unknown function (DUF386) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF386 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_03813 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 5245366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3340752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)TVDDDER MGYG000000188_00824 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp003462685|m__MGYG000000188 1.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CUJQ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 pathway, signal sequence 1.0 - 1.0 - 1.0 - 1.0 ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000188_00824 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3943507 2142077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)VELIQEGFR MGYG000000003_01804 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,2FM6J@200643|Bacteroidia,4AMTF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_2,SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_01804 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 3619543 0 0 0 3171416 0 0 0 0 0 5123313 0 3135095 5497145 0 0 0 0 0 4811880 2512170 0 4330978 0 3736204 0 0 0 7182583 0 3428794 0 0 2710540 4303371 3846746 0 277211 253198 0 0 0 116706 0 0 0 0 0 203812 0 347892 353387 0 0 0 0 0 314474 196813 0 342413 0 232806 0 0 0 430433 0 433033 0 0 179441 194821 287309 0 234674 337302 0 0 0 320105 0 0 0 0 0 450263 0 245998 0 0 0 0 0 0 0 0 0 448637 0 176493 0 0 0 321833 0 0 0 0 347504 227017 129263 0 0 171118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 652965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)VGEAIVEATK MGYG000000013_01224;MGYG000002549_02739;MGYG000002281_01909;MGYG000000138_00869;MGYG000000044_00323;MGYG000004876_02584;MGYG000002455_00199;MGYG000004185_02169 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 0.75 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_01224 0.125 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3130736 0 0 0 0 0 0 0 0 4323967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)VIKPSTLGLELK MGYG000001306_00997 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,2FKZT@200643|Bacteroidia,4AMS4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG NOG06228 non supervised orthologous group 1.0 susB 1.0 GO:0000272,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0004558,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:0090599,GO:1901575 1.0 3.2.1.20,3.2.1.3 1.0 ko:K01187,ko:K21574 1.0 ko00052,ko00500,ko01100,map00052,map00500,map01100 1.0 - 1.0 R00028,R00801,R00802,R01790,R01791,R06087,R06088 1.0 RC00028,RC00049,RC00077 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH31,GH97 1.0 - 1.0 GH97_C,GH97_N,Glyco_hydro_97 1.0 3.2.1.3|3.2.1.20 1.0 GH97 1.0 GH97 1.0 GH97 1.0 MGYG000001306_00997 1.0 alpha-glucosidase. | glucan 1,4-alpha-glucosidase. maltase-glucoamylase. | lysosomal alpha-glucosidase. Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.-!-The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links. | Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides.-!-This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides.-!-EC 3.2.1.20 from mammalian intestine can catalyze similar reactions. Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. | Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose. 1.0 1.0 1.0 1.0 Galactose metabolism|Starch and sucrose metabolism|Metabolic pathways 1.0 K01187:malZ; alpha-glucosidase [EC:3.2.1.20]|K21574:susB; glucan 1,4-alpha-glucosidase [EC:3.2.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1910228 0 0 0 0 2797522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116945 0 0 0 0 78119 0 0 0 0 75298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)VLELAGLK MGYG000001315_01353;MGYG000004733_00985;MGYG000000201_02098;MGYG000001423_01155;MGYG000000301_00177;MGYG000001338_02790;MGYG000002854_00092;MGYG000001689_02303;MGYG000000142_02050;MGYG000000133_00062;MGYG000000212_03064;MGYG000000213_00197;MGYG000000184_01189;MGYG000002938_00273;MGYG000000216_02346;MGYG000004852_00027;MGYG000000251_01814;MGYG000004667_05119 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01353 0.05555555555555555 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)VNDIVLSK MGYG000000045_02152 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria 1.0 2|Bacteria 1.0 C 1.0 hydroxyacid-oxoacid transhydrogenase activity 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iSB619.SA_RS00885 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000045_02152 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1606959 0 0 0 0 1011676 0 0 0 0 1581845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333598 0 0 0 0 358189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232759 0 0 0 0 519277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850842 0 0 0 0 344809 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)VVEEFNPGFTPDNK MGYG000003684_03047 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eisenbergiella|s__Eisenbergiella massiliensis|m__MGYG000003684 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,36DD9@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ECH_1,ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003684_03047 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1968297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)YDPAAK MGYG000000074_00680 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1409@1|root,COG1409@2|Bacteria,4NF9K@976|Bacteroidetes,2FPK8@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 C terminal of Calcineurin-like phosphoesterase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Metallophos,MetallophosC,MetallophosN,PQQ_2,PQQ_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00680 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2143195 0 0 0 0 0 0 0 1836404 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Thr)YLVSK MGYG000003170_00231 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__Sutterella sp900764215|m__MGYG000003170 1.0 COG2885@1|root,COG2885@2|Bacteria,1N6EM@1224|Proteobacteria,2VM27@28216|Betaproteobacteria,4PQDC@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 M 1.0 OmpA family 1.0 ompA 1.0 - 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 - 1.0 DUF1134,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003170_00231 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03286:TC.OOP; OmpA-OmpF porin, OOP family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1488625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Trp)DAIIIR MGYG000000243_00366;MGYG000001787_00809 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00366 0.5 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1.0 none 1.0 0 0 1442048 0 0 0 0 0 0 0 1030475 0 0 0 0 0 0 2350766 0 0 0 0 3253673 0 0 0 0 4976848 0 0 0 0 1156184 0 0 0 0 1028630 0 0 1422310 0 0 0 0 0 0 0 1209956 0 0 0 0 0 0 6334840 0 0 0 0 2423800 0 0 0 0 2573609 0 0 0 0 1894718 0 0 0 0 372805 0 0 777190 0 0 0 0 0 0 0 707235 0 0 0 0 0 0 378737 0 0 0 0 475260 0 0 0 0 578111 0 0 0 0 532642 0 0 0 0 114530 0 0 53418 0 0 0 0 0 0 0 878153 0 0 0 0 0 0 2114477 0 0 0 0 1011619 0 0 0 0 1560684 0 0 0 0 1389748 0 0 0 0 67672 0 0 383934 0 0 0 0 0 0 0 146259 0 0 0 0 0 0 63086 0 0 0 0 792316 0 0 0 0 2319972 0 0 0 0 214722 0 0 0 0 331452 +A(Ala->Trp)NAIIIR MGYG000002455_04590;MGYG000000029_02971;MGYG000004876_03505;MGYG000003681_00721;MGYG000001306_01782;MGYG000000098_01490;MGYG000003367_00322;MGYG000000196_03462;MGYG000001337_02575;MGYG000001346_03050 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 0.6 976|Bacteroidetes 1.0 C 0.6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 0.6 serA 0.6 - 1.0 1.1.1.399,1.1.1.95 0.6 ko:K00058 0.6 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 0.6 M00020 0.6 R01513 0.6 RC00031 0.6 ko00000,ko00001,ko00002,ko01000,ko04147 0.6 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 0.6 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_04590 0.1 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 0.6 0.6 0.6 0.6 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 0.6 none 1.0 0 0 0 83638889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72176315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325140889 0 0 0 64633128 436479536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31632697 0 0 0 51107003 35309327 0 34958338 0 0 0 0 0 0 0 0 0 0 0 0 33416513 77537611 40563642 0 0 33180140 0 0 40444571 0 0 0 0 0 0 0 40285592 0 36046225 48177594 45335947 0 42501611 0 48921675 43298712 0 0 39780800 0 42938437 0 35125482 40649428 100375912 0 43085585 0 0 181288197 32797543 0 55263490 0 50856460 0 40470734 0 0 0 0 0 0 45195078 0 0 0 0 0 0 0 0 0 0 0 0 0 23269634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Trp)NAIILR MGYG000001302.1_00942;MGYG000004876_03505;MGYG000004763_00834;MGYG000003681_00721;MGYG000001835_00780;MGYG000000196_03462;MGYG000001337_02575;MGYG000001346_03050 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 C 0.5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 0.75 serA 0.625 - 1.0 1.1.1.399,1.1.1.95 0.75 ko:K00058 0.75 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 0.75 M00020 0.75 R01513 0.75 RC00031 0.75 ko00000,ko00001,ko00002,ko01000,ko04147 0.75 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_00942 0.125 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 0.75 0.75 0.75 0.75 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.75 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6586980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59691534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 43714184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31883747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Trp)NALIIR MGYG000002455_04590;MGYG000001302.1_00942;MGYG000000029_02971;MGYG000003312_01933;MGYG000004876_03505;MGYG000004763_00834;MGYG000000013_04188;MGYG000001306_01782;MGYG000002561_02267;MGYG000000196_03462;MGYG000002549_01443;MGYG000001337_02575;MGYG000004899_01858;MGYG000001345_02371;MGYG000000224_02581;MGYG000003681_00721;MGYG000000098_01490;MGYG000001789_00954;MGYG000001346_03050 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,4AKHC@815|Bacteroidaceae 0.47368421052631576 976|Bacteroidetes 1.0 C 0.47368421052631576 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 0.5789473684210527 serA 0.5263157894736842 - 1.0 1.1.1.399,1.1.1.95 0.5789473684210527 ko:K00058 0.5789473684210527 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 0.5789473684210527 M00020 0.5789473684210527 R01513 0.5789473684210527 RC00031 0.5789473684210527 ko00000,ko00001,ko00002,ko01000,ko04147 0.5789473684210527 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 0.5789473684210527 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_04590 0.05263157894736842 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 0.5789473684210527 0.5789473684210527 0.5789473684210527 0.5789473684210527 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.5789473684210527 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 0.5789473684210527 none 1.0 0 65431464 70540623 0 53580727 0 0 0 75540820 90240795 0 0 0 0 0 0 75484408 0 0 0 0 54374974 186704583 0 0 77820892 76373441 224554865 0 84137313 0 82568109 62351865 59896871 0 0 0 0 38712673 0 0 47839133 0 0 0 55372214 0 0 65697993 55658064 0 0 53996097 0 0 0 0 0 47157591 0 0 0 0 0 0 383517300 0 0 49836555 0 0 0 48569031 0 48453152 52198027 0 0 0 0 39803486 0 0 0 0 0 0 0 0 33031058 0 27214992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 35870667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360783 0 0 0 144372829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Trp)NALLIR MGYG000004763_00834;MGYG000001789_00954 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia,22WZN@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 CH 0.5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004763_00834 0.5 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32015262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Tyr)ATLMLK MGYG000002549_01341 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG3637@1|root,COG3637@2|Bacteria,4PM3D@976|Bacteroidetes,2G0AF@200643|Bacteroidia,4AV3U@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_01341 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 1005203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1624947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 667531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Tyr)IAPDETPLYR MGYG000002438_01883 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 435591.BDI_2653|- 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01883 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3295228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Tyr)VAEGANMPTTR MGYG000000095_00309 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__GCA-900066755|s__GCA-900066755 sp902363085|m__MGYG000000095 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,21ZF0@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 - 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000095_00309 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 1028704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Tyr)YSSGKPALGVGAGNTPVIIDDTADVR MGYG000000133_00993 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00993 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2398942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1721565 0 0 0 0 2055320 +A(Ala->Val)AGQIDC(Carbamidomethyl)SR MGYG000002506_04505;MGYG000002323_00920 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG3477@1|root,COG3477@2|Bacteria,1MV9E@1224|Proteobacteria,1RYHM@1236|Gammaproteobacteria,3XQGU@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 response to acidic pH 1.0 yagU 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016020,GO:0044464,GO:0050896,GO:0071944 1.0 - 1.0 ko:K08996 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF1440 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04505 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K08996:yagU; putative membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4207997 0 0 0 9567726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8005675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)AITPVVNATVER MGYG000002794_00763;MGYG000002143_01959;MGYG000001733_00672;MGYG000004196_01673;MGYG000004475_00752 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_00763 0.2 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K01844:kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)ALQYSTTEGFPR MGYG000001733_01320 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900550615|m__MGYG000001733 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,25WJ6@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 EK 1.0 Aminotransferase class I and II 1.0 - 1.0 - 1.0 - 1.0 ko:K05825 1.0 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 1.0 - 1.0 R01939 1.0 RC00006 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2,GntR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001733_01320 1.0 - - - - 1.0 1.0 1.0 1.0 Lysine biosynthesis|Metabolic pathways|2-Oxocarboxylic acid metabolism 1.0 K05825:LYSN; 2-aminoadipate transaminase [EC:2.6.1.-] 1.0 none 1.0 745341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)AQGILTVR MGYG000000463_01481;MGYG000002114_00088;MGYG000002229_00282;MGYG000002006_01658;MGYG000004482_00393;MGYG000004594_00959;MGYG000004667_00970;MGYG000002727_00240;MGYG000001319_00729;MGYG000004680_00577;MGYG000000145_01088;MGYG000004760_00878;MGYG000002670_01671;MGYG000001688_03814;MGYG000001698_00702;MGYG000002926_01683;MGYG000001757_01805;MGYG000002143_00035;MGYG000002057_00345;MGYG000000728_00587;MGYG000002103_01314;MGYG000000084_02423;MGYG000000205_02701;MGYG000000152_05136;MGYG000004663_01541;MGYG000004866_01724;MGYG000002059_01602;MGYG000004380_01725;MGYG000002025_01833;MGYG000004475_00310;MGYG000003422_01232;MGYG000000242_00224;MGYG000002139_00077;MGYG000002794_01254;MGYG000004718_01489;MGYG000004517_00262;MGYG000001733_00637;MGYG000000175_01356;MGYG000002552_02286;MGYG000000404_01435;MGYG000000387_01345;MGYG000004784_01123;MGYG000002492_01692;MGYG000004845_02015;MGYG000001439_01567;MGYG000000371_01679;MGYG000000489_00801;MGYG000000281_03419;MGYG000000142_02834;MGYG000002702_00763;MGYG000002099_01951;MGYG000004487_00114;MGYG000000233_02503;MGYG000000031_02405;MGYG000001619_00896;MGYG000000179_00100;MGYG000000690_00823;MGYG000003074_00103;MGYG000000255_02207;MGYG000001564_02842;MGYG000000198_00250;MGYG000002945_01502;MGYG000001496_03326;MGYG000003921_01571;MGYG000001748_00979;MGYG000001675_00187;MGYG000003628_00298;MGYG000001646_00500;MGYG000003656_02122;MGYG000002925_01270;MGYG000002126_00460;MGYG000003694_01656;MGYG000001637_01169;MGYG000000087_02439 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.17567567567567569 186801|Clostridia 1.0 G 0.9459459459459459 Belongs to the PEP-utilizing enzyme family 0.6756756756756757 ppdK 0.9459459459459459 - 1.0 2.7.9.1 0.9459459459459459 ko:K01006 0.9459459459459459 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.9459459459459459 M00169,M00171,M00172,M00173 0.9459459459459459 R00206 0.9459459459459459 RC00002,RC00015 0.9459459459459459 ko00000,ko00001,ko00002,ko01000 0.9459459459459459 - 0.9459459459459459 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9459459459459459 - 1.0 - 1.0 - 1.0 GT1 0.9459459459459459 MGYG000000463_01481 0.013513513513513514 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.9459459459459459 0.9459459459459459 0.9459459459459459 0.9459459459459459 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 0.9459459459459459 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 0.9459459459459459 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)ASNESFGYNTDEIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.16666666666666666 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1052204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2020899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12679346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3503042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)ATILAK MGYG000000271_01703;MGYG000004271_02802 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the cysteine synthase cystathionine beta- synthase family 1.0 cysK 1.0 - 1.0 2.5.1.47 1.0 ko:K01738 1.0 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00021 1.0 R00897,R03601,R04859 1.0 RC00020,RC02814,RC02821 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PALP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_01703 0.5 cysteine synthase. OAS sulfhydrylase. Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors.-!-Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53.-!-Formerly EC 4.2.99.8. hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Sulfur metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01738:cysK; cysteine synthase [EC:2.5.1.47] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)AVEAAPK MGYG000003770_00148;MGYG000002707_01485;MGYG000000099_00102;MGYG000002944_00191 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,269AI@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003770_00148 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 998814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1169392 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)AVEADLKDLK MGYG000002528_00169 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00169 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2183757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)DKEMTAAGK MGYG000000084_02247;MGYG000001157_02455 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000084_02247 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94029 0 0 0 0 0 0 0 0 0 0 0 61823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4371399 0 1345855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193644 0 0 0 0 541842 0 0 0 0 587015 0 497520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 813024 0 0 0 0 44673 0 0 0 0 485466 0 189529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)GEVYNVGGHNEK MGYG000001599_00610 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900544075|m__MGYG000001599 1.0 COG1088@1|root,COG1088@2|Bacteria,4NE9V@976|Bacteroidetes,2FMUH@200643|Bacteroidia,4AME0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily 1.0 rfbB 1.0 - 1.0 4.2.1.46 1.0 ko:K01710 1.0 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 1.0 M00793 1.0 R06513 1.0 RC00402 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001599_00610 1.0 dTDP-glucose 4,6-dehydratase. - - dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. 1.0 1.0 1.0 1.0 Streptomycin biosynthesis|Polyketide sugar unit biosynthesis|Acarbose and validamycin biosynthesis|Biosynthesis of vancomycin group antibiotics 1.0 K01710:rfbB, rmlB, rffG; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)HLATIEGK MGYG000002517_00959;MGYG000000562_02319;MGYG000000389_00578;MGYG000000154_00174 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 0.75 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002517_00959 0.25 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 662327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1875934 0 0 0 0 2047157 0 0 0 0 1543137 0 0 0 0 0 0 0 0 0 0 0 416382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 871996 0 0 0 0 1761301 0 0 0 0 1436739 0 0 0 0 0 0 0 0 0 0 0 2528571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6357689 0 0 0 0 4242338 0 0 0 0 4287862 0 0 0 0 0 0 0 0 0 0 0 560369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2014991 0 0 0 0 326474 0 0 0 0 1374954 0 0 0 0 0 0 0 0 0 0 0 247151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1634145 0 0 0 0 1356881 0 0 0 0 1183286 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)HLATLEGK MGYG000002963_01235 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerosporobacter|s__Anaerosporobacter mobilis|m__MGYG000002963 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,36EA6@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002963_01235 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2281945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)IAEAIAEATK MGYG000001835_00603 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp000432735|m__MGYG000001835 1.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NIEK@976|Bacteroidetes,2FMAP@200643|Bacteroidia,4AKI4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 Psort location CytoplasmicMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001835_00603 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2738644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)LQEAVYNYIK MGYG000001345_01307;MGYG000001378_03234;MGYG000000013_03191 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,27W9G@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 NADH:flavin oxidoreductase / NADH oxidase family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Oxidored_FMN,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_01307 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 960538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)LVLVNLAPR MGYG000000074_02196 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,2FNV6@200643|Bacteroidia,22U5Q@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation 1.0 metG 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.10 1.0 ko:K01874 1.0 ko00450,ko00970,map00450,map00970 1.0 M00359,M00360 1.0 R03659,R04773 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,tRNA-synt_1g,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 GH55 1.0 MGYG000000074_02196 1.0 methionine--tRNA ligase. MetRS. In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9. ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met). 1.0 1.0 1.0 1.0 Selenocompound metabolism|Aminoacyl-tRNA biosynthesis 1.0 K01874:MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 778694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)LVVTGAGEK MGYG000000233_02445 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,21Z2Z@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 I 1.0 Enoyl-CoA hydratase/isomerase 1.0 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02445 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1725428 0 0 0 0 0 0 1328187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Val)SAAVDAQAEAIKNQASSTVDAQAEAIR MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00272 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01421:yhgE; putative membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146494 0 0 0 0 0 0 0 0 +A(Ala->Val)TIIGHIQR MGYG000000255_02050;MGYG000000233_02644;MGYG000000087_01570;MGYG000000205_01904 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,21XPK@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_02050 0.25 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1995379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1314235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228756 0 0 0 0 0 0 0 0 0 0 1248724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1162959 0 0 0 0 0 0 1165025 0 0 0 0 +A(Ala->Val)YEPDTAQSELGVVLR MGYG000000074_02075 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF4@976|Bacteroidetes,2G3EZ@200643|Bacteroidia,22VH9@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02075 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 273279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550080 0 0 0 0 0 0 0 0 0 0 0 0 0 295335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 801581 0 0 0 0 0 0 0 0 0 0 0 0 0 1579812 0 468245 0 830502 0 0 0 0 0 1808491 0 0 0 0 0 0 0 0 +A(Ala->Xle)GIVGLPNVGK MGYG000001346_01808;MGYG000000224_00729;MGYG000003470_01179 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0012@1|root,COG0012@2|Bacteria,4NF7N@976|Bacteroidetes,2FMWX@200643|Bacteroidia,4AMIJ@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 J 1.0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner 1.0 ychF 1.0 - 1.0 - 1.0 ko:K06942 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 MMR_HSR1,YchF-GTPase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_01808 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06942:ychF; ribosome-binding ATPase 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3016179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3318986 0 0 0 0 0 0 0 0 0 0 +A(Ala->Xle)IDPAAMAK MGYG000001310_00280;MGYG000002772_01916;MGYG000000249_01751 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 0.6666666666666666 adh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_00280 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13718540 0 0 0 0 0 0 0 0 0 0 0 7610580 0 0 0 6718743 0 0 11789113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7306401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Xle)SYGETGLDESAGR MGYG000002721_02202 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-873|s__CAG-873 sp009775195|m__MGYG000002721 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002721_02202 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1530372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Ala->Xle)VDLLVEGK MGYG000000159_01307 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Sellimonas|s__Sellimonas intestinalis|m__MGYG000000159 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,2682U@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000159_01307 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Carbonyl)ALNPHIVVK MGYG000000243_01624;MGYG000002478_03826 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0176@1|root,COG0176@2|Bacteria,4NFVZ@976|Bacteroidetes,2FNM3@200643|Bacteroidia,4AM98@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616,ko:K08314 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CBS,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01624 0.5 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00616:TALDO1, talB, talA; transaldolase [EC:2.2.1.2]|K08314:fsaB, talC; fructose-6-phosphate aldolase 2 [EC:4.1.2.-] 1.0 none 1.0 915606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3999893 0 0 0 0 3275601 0 0 1392551 0 4398963 0 0 0 0 0 0 0 0 1030087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2000703 0 0 0 0 1914765 0 0 970678 0 1637691 0 0 0 0 0 0 0 0 919619 0 88856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 799347 0 0 0 0 476655 0 0 86609 0 0 0 0 0 0 0 0 0 0 216602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +A(Carbonyl)TGAMAALLK MGYG000002517_01537 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia 1.0 186801|Clostridia 1.0 H 1.0 Belongs to the formate--tetrahydrofolate ligase family 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01537 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01938:fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1121469 0 0 0 0 0 0 0 0 +AA(Ala->Asp)AAAAEAEAK MGYG000002293_01607 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01607 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1562231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 782546 0 2545259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Asp)YLFNHVEYR MGYG000004893_00001 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A sp900555485|m__MGYG000004893 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,378RN@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000004893_00001 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 909059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Glu)AGTAAVSAAEQTK MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00272 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01421:yhgE; putative membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 712537 0 0 0 2585726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564808 0 939275 0 0 0 0 0 2101365 0 0 0 0 0 0 0 0 +AA(Ala->Gly)ADLLVLAYHR MGYG000003695_00289;MGYG000004558_01494;MGYG000000249_00466;MGYG000003581_01363;MGYG000002279_00355;MGYG000002992_01118;MGYG000001338_01660;MGYG000000038_02127;MGYG000000184_00391 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily 1.0 rfbB 1.0 - 1.0 4.2.1.46 1.0 ko:K01710 1.0 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 1.0 M00793 1.0 R06513 1.0 RC00402 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000003695_00289 0.1111111111111111 dTDP-glucose 4,6-dehydratase. - - dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. 1.0 1.0 1.0 1.0 Streptomycin biosynthesis|Polyketide sugar unit biosynthesis|Acarbose and validamycin biosynthesis|Biosynthesis of vancomycin group antibiotics 1.0 K01710:rfbB, rmlB, rffG; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 734508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374927 0 0 0 0 0 0 422276 0 0 0 0 0 127121 0 0 0 0 0 0 0 0 0 0 435939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Gly)DDAAGLAISEK MGYG000001777_01359;MGYG000003422_01458;MGYG000000362_01735;MGYG000003422_01457;MGYG000000217_00038;MGYG000002934_00200;MGYG000001814_01561;MGYG000001514_01163 domain d__Bacteria 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae 0.375 186801|Clostridia 0.75 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 0.625 - 0.75 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001777_01359 0.125 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2066248 0 0 0 0 2041449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Gly)DDAAGLSISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001777_01322 0.022727272727272728 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 1741351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1423102 0 0 0 0 0 1327070 0 0 1277453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 811255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Gly)DDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6465599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Gly)MLAIMNPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1186600 1929629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Gly)MLTIMNPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1270812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Pro)AQNIVPNTTGAAK MGYG000003504_01686 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-314|g__CAG-1435|s__CAG-1435 sp003537755|m__MGYG000003504 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003504_01686 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 922961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Pro)DDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 450601 0 0 0 0 0 238147 0 0 0 0 0 0 0 0 0 0 0 813230 1449754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 901162 0 0 0 0 0 1533606 0 0 0 0 1420442 0 0 0 0 0 0 1827625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1658723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Ser)ASESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Ser)DDAAGLSISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001777_01322 0.022727272727272728 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1234319 0 0 0 0 0 3811613 1413880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 206224 0 0 0 0 472723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290497 0 0 0 0 0 0 350711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 576997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Ser)DDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 255137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154083 0 215493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374076 0 514002 235175 386252 403483 558404 339260 0 849515 564977 443007 481058 274683 0 419424 475396 0 442030 0 0 424972 0 435456 401036 0 363578 187508 488052 0 247655 293391 673703 268590 377886 347088 274650 718055 256875 0 332214 0 342305 407996 367192 0 349419 0 0 0 0 207649 0 0 388615 168261 0 0 528267 490914 558691 299417 304613 0 209663 0 227506 0 475534 0 0 0 0 0 244201 186349 367087 0 0 152287 0 0 0 455375 0 0 0 0 0 343780 0 0 0 0 507154 440935 0 175810 0 0 370393 502124 0 0 264012 0 0 0 0 334224 333374 330530 0 0 19627721 7401456 11577962 7134919 7924266 21446020 18003105 10021905 28255393 21564367 8004535 54534562 21692731 15544662 22120373 8808892 24834696 3990712 25509650 32257591 14649337 13075779 3144264 16042796 17975935 22555573 16242184 3381047 3922889 34171633 5229084 4806555 9073431 25909040 10244195 16101614 26743766 13960548 +AA(Ala->Ser)GAAGVIRPSK MGYG000001300_00059;MGYG000003899_00538;MGYG000002641_02329;MGYG000002610_01595;MGYG000004719_01899;MGYG000003166_01772;MGYG000003921_01901;MGYG000001157_01521;MGYG000003937_01168;MGYG000000573_01714;MGYG000000589_01770;MGYG000000084_01199;MGYG000004732_01998 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 0.9230769230769231 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 0.9230769230769231 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00059 0.07692307692307693 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Phosphotransferase system (PTS) 1.0 K02803:nagEb; N-acetylglucosamine PTS system EIIB component [EC:2.7.1.193]|K02804:nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2539535 0 +AA(Ala->Ser)LPSTTFDGTYLR MGYG000003697_02264 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG4772@1|root,COG4772@2|Bacteria,4NF0U@976|Bacteroidetes,2FM7N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_02264 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1329778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1004011 0 0 0 0 1336922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Ser)PILLEPIMR MGYG000000171_02843;MGYG000004733_01212 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000000171_02843 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Ser)VDAGAASAR MGYG000002854_00976 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Peptostreptococcaceae|g__Peptacetobacter|s__Peptacetobacter sp900539645|m__MGYG000002854 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,22HEI@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002854_00976 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12172014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8744214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Ser)VETGADAAGR MGYG000000249_01483;MGYG000004799_00497;MGYG000001379_02073;MGYG000000268_01898;MGYG000002596_02056 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_01483 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1452056 0 0 0 0 0 0 0 0 0 0 0 0 3098360 0 0 0 0 2385639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Thr)AQTDNVHRPFYPMLIFR MGYG000002469_00856 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium breve|m__MGYG000002469 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002469_00856 1.0 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K01621:xfp, xpk; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 501548 1174442 0 0 0 0 0 0 0 0 0 842328 970570 0 0 0 0 0 0 0 0 0 955169 973452 0 0 0 978235 0 834415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Thr)ASESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2311699 0 0 0 0 0 0 0 3496962 0 0 0 0 3946242 0 0 0 0 0 0 0 3440651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13542061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6493339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 767866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5720695 0 0 0 0 0 0 0 5148507 0 0 0 0 0 0 0 0 0 0 0 0 5988994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Thr)ASESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 961374 0 0 0 0 0 0 0 0 0 0 0 0 933804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1091767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1014733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Thr)EAYFLLAEAK MGYG000002478_01404;MGYG000004797_04332 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01404 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1708918 1850725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2112786 0 1483055 0 0 0 0 0 0 0 2045308 0 1641716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Thr)EIPEAIR MGYG000000136_02061;MGYG000002670_00403;MGYG000001315_01353;MGYG000002234_01458;MGYG000004733_00985;MGYG000003891_01006;MGYG000000252_01802;MGYG000000280_01284;MGYG000000031_02249;MGYG000000142_02050;MGYG000004630_00952;MGYG000002492_00392;MGYG000000135_01188;MGYG000000690_01576;MGYG000000028_01605;MGYG000004689_01598;MGYG000002517_02856;MGYG000000002_00865;MGYG000002966_02558;MGYG000001186_01095;MGYG000000213_00197;MGYG000004296_00406;MGYG000000806_01299;MGYG000002278_02309;MGYG000000050_01189;MGYG000002298_00345;MGYG000000193_02113;MGYG000000201_02098;MGYG000000301_00177;MGYG000004879_01580;MGYG000001338_02790;MGYG000002528_01856;MGYG000000164_02747;MGYG000001689_02303;MGYG000000562_01931;MGYG000000133_00062;MGYG000000212_03064;MGYG000000184_01189;MGYG000003694_02445;MGYG000000216_02346;MGYG000000251_01814;MGYG000001637_00014;MGYG000000187_01741 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.46511627906976744 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000136_02061 0.023255813953488372 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3864447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Thr)LGAGVDKLANTVR MGYG000000245_00416;MGYG000002492_02075;MGYG000004271_02056;MGYG000000489_01318;MGYG000000271_00294 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000245_00416 0.2 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Thr)VLVPNDVSNEAR MGYG000000179_03320;MGYG000001311_00514 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,268FE@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 P 1.0 NLPA lipoprotein 1.0 metQ 1.0 - 1.0 - 1.0 ko:K02073 1.0 ko02010,map02010 1.0 M00238 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.24 1.0 - 1.0 - 1.0 Lipoprotein_9,SBP_bac_3,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03320 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K02073:metQ; D-methionine transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2402120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Val)ALGFFEAAGYTVENGK MGYG000002926_01410 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_01410 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 314430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296495 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907748 0 0 0 0 1177227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Val)ASESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 909114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 653043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Val)EAPATEEPKAESAE MGYG000000236_01758 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,2FNPH@200643|Bacteroidia,4AK8D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal protein L17 1.0 rplQ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02879 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Ribosomal_L17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_01758 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02879:RP-L17, MRPL17, rplQ; large subunit ribosomal protein L17 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1326408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Val)EDLLDAEAYK MGYG000000196_02494 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0509@1|root,COG0509@2|Bacteria,4NQ35@976|Bacteroidetes,2FT3J@200643|Bacteroidia,4AQKP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein 1.0 gcvH 1.0 - 1.0 - 1.0 ko:K02437 1.0 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 1.0 M00532 1.0 R01221 1.0 RC00022,RC02834 1.0 ko00000,ko00001,ko00002 1.0 - 1.0 - 1.0 - 1.0 GCV_H 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_02494 1.0 - - - - 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Glyoxylate and dicarboxylate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Carbon metabolism 1.0 K02437:gcvH, GCSH; glycine cleavage system H protein 1.0 none 1.0 1181914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154204 0 +AA(Ala->Val)ITPVVNATVER MGYG000002794_00763;MGYG000002143_01959;MGYG000001733_00672;MGYG000004196_01673;MGYG000004475_00752 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_00763 0.2 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K01844:kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3] 1.0 none 1.0 1190375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 914957 0 0 0 0 0 0 0 0 0 0 1090272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AA(Ala->Val)TQALGMIETK MGYG000000413_00044 genome d__Bacteria|p__Firmicutes_B|c__Peptococcia|o__Peptococcales|f__Peptococcaceae|g__UBA7185|s__|m__MGYG000000413 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3WM1H@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000413_00044 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAA(Ala->Asn)SESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1623239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAA(Ala->Asp)SESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004884_01637 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 862830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAA(Ala->Met)GTAAVSAAEQTK MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00272 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01421:yhgE; putative membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3917630 0 0 0 0 +AAA(Ala->Met)QNIVPNTTGAAK MGYG000003504_01686 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-314|g__CAG-1435|s__CAG-1435 sp003537755|m__MGYG000003504 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003504_01686 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAA(Ala->Ser)SESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAA(Ala->Thr)SESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2792354 7638729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6807142 0 0 0 0 4898068 7027324 0 0 0 0 0 0 0 0 0 0 6362155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1606096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4439376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1321407 0 0 0 0 0 563369 0 0 0 0 0 0 0 0 0 0 672941 0 0 0 0 0 0 0 0 +AAA(Ala->Thr)SESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 939875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 679894 0 997245 0 0 0 0 805230 0 0 0 0 0 0 509769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAA(Ala->Thr)SESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004884_01637 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1255091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAAAAAEAAAETEATEEAPAEA MGYG000003697_02087;MGYG000002834_00364 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_02087 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 352779 0 380553 0 0 0 0 0 0 531369 0 0 0 338253 0 146190 0 0 0 0 365782 0 0 0 0 0 0 0 0 0 481551 0 0 0 0 0 0 0 0 0 522675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1296181 0 716319 0 0 0 0 0 0 872996 0 0 0 647398 0 2380515 0 0 0 0 5463481 0 0 0 0 2163485 0 0 0 0 841796 0 0 0 0 926969 0 0 1273223 0 299613 0 0 0 0 0 0 0 0 0 0 433692 0 405385 0 0 0 0 0 0 0 0 0 239950 0 0 0 0 2127202 0 0 0 0 0 +AAAAAAAAK MGYG000003279_02451 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900541585|m__MGYG000003279 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003279_02451 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2491599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAADTSAADKPADEGKAE MGYG000001292_00236 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG3937@1|root,COG3937@2|Bacteria,2GS3M@201174|Actinobacteria,4D1FE@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 S 1.0 granule-associated protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Phasin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001292_00236 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1476068 0 0 0 0 143773 0 0 0 0 1136758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAALDSLPEAWK MGYG000001313_01371 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG4221@1|root,COG4221@2|Bacteria,4NE1R@976|Bacteroidetes,2FR40@200643|Bacteroidia,4AMEY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Belongs to the short-chain dehydrogenases reductases (SDR) family 1.0 ydfG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,adh_short 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_01371 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355616 0 0 0 0 0 0 0 0 0 266036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479453 0 0 0 0 456814 0 0 0 0 282597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397245 0 0 0 0 622761 0 0 0 0 462006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAALQTPLYSYLGGIHVGK MGYG000001607_00631 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_B|s__Dorea_B phocaeensis|m__MGYG000001607 1.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,21XMD@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000001607_00631 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAAQVER MGYG000004797_04190 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0845@1|root,COG0845@2|Bacteria,4NECC@976|Bacteroidetes,2FMDD@200643|Bacteroidia,4ANZR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Auxiliary transport protein, membrane fusion protein (MFP) family protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01993 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_04190 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01993:ABC-2.TX; HlyD family secretion protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 767428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1116139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 627717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1456868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAADFGDGSQIDR MGYG000001302.1_02383 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG5492@1|root,COG5492@2|Bacteria,4NIA5@976|Bacteroidetes,2FN73@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 N 1.0 domain, Protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glug,Mfa_like_1,Peptidase_M26_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_02383 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 608258 864236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 845023 0 0 0 0 0 0 0 0 0 0 0 0 0 592431 0 0 0 0 443767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 703828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 493144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209110 +AAAADVGNDHR MGYG000002492_00629;MGYG000001637_01195;MGYG000003694_02366 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 1.0 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00629 0.3333333333333333 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Glyoxylate and dicarboxylate metabolism|Nitrogen metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Biosynthesis of amino acids|Two-component system|Necroptosis|Glutamatergic synapse|GABAergic synapse 1.0 K01915:glnA, GLUL; glutamine synthetase [EC:6.3.1.2] 1.0 none 1.0 31905 115432 147032 112946 176751 0 124184 131828 109082 244307 248716 0 196010 0 253480 84685 141933 299732 0 79626 126155 149088 232762 0 145262 0 55744 290716 141707 0 108770 31818 84529 72473 0 0 0 147052 361168 343845 382194 565653 763658 211220 599668 486195 341100 263405 532589 269053 671571 337692 308081 457687 196895 3857790 0 373413 426295 192679 2236062 373814 260464 375973 494374 4286980 312293 120725 563573 345271 418970 381521 301833 456384 272191 512720 438838 901728 1940165 748760 649644 689890 477994 749285 704563 624081 1014732 806012 950597 820044 947742 1480506 670851 99791 0 812916 837607 911962 760986 643988 662513 795756 698545 1483753 913282 606449 1034684 762431 2596579 1043125 733487 620305 852680 2548482 68913 0 95216 0 60120 48487 147083 0 126590 107912 162263 0 0 83625 0 196084 78805 856546 0 31236 0 169522 93977 106693 0 44419 40052 984710 101735 115413 294950 0 122808 0 0 0 0 268012 0 0 0 0 0 0 76937 0 0 0 0 0 0 111156 172870 0 0 0 0 0 114785 72618 0 82348 0 0 90702 0 0 0 44009 49276 111128 0 115750 241258 0 0 +AAAAEAAAETEATEEAPAEA MGYG000003697_02087;MGYG000002834_00364 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_02087 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053725 0 625522 852680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1190977 0 1057550 0 0 0 0 0 0 0 0 642336 0 0 0 0 895087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAEGNEDAKNAIEVLC(Carbamidomethyl)YGIAK MGYG000000201_02960 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066145|m__MGYG000000201 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_02960 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAEQEVIADDAAESAAE MGYG000003937_01585 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,3WKHQ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01585 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 608137 0 0 0 0 0 0 0 0 0 0 0 0 0 285916 0 0 680468 0 900950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAETLADVK MGYG000001345_01346;MGYG000002549_00032;MGYG000000196_04075 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0180@1|root,COG0180@2|Bacteria,4NETX@976|Bacteroidetes,2FMAT@200643|Bacteroidia,4AP4X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the class-I aminoacyl-tRNA synthetase family 1.0 trpS 1.0 - 1.0 6.1.1.2 1.0 ko:K01867 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03664 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 tRNA-synt_1b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_01346 0.3333333333333333 tryptophan--tRNA ligase. tryptophanyl-tRNA synthetase. - ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + H(+) + L-tryptophanyl-tRNA(Trp). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01867:WARS, trpS; tryptophanyl-tRNA synthetase [EC:6.1.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 963907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 661554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 817419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAEYLDTYADGSK MGYG000002528_01780 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002528_01780 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1345948 0 0 0 0 809370 170916 0 0 0 1256313 1601304 0 0 135972 0 0 404169 0 0 448433 590203 4041027 573575 0 784155 2191981 0 0 0 0 0 0 0 0 0 0 0 7038234 0 0 0 1495883 4280240 5133887 0 0 0 6609221 415822 0 2591751 1609280 525879 0 360916 0 0 836236 212199 3474569 2285444 0 948172 5126887 0 0 0 0 1073725 0 0 0 0 0 0 1239435 0 0 0 15219841 2268161 3293219 0 581096 0 2888090 7292317 0 0 4303731 2627506 0 293628 0 374689 2694952 0 240297 0 0 0 0 0 0 0 0 153989 0 0 0 0 0 0 332074 0 0 0 0 506264 0 0 121746 0 335779 7138559 0 104684 3982998 0 0 0 0 67100 0 0 0 0 0 218992 0 0 0 0 0 0 0 0 0 0 0 0 594132 0 0 0 532079 915178 0 0 0 0 923704 0 0 0 0 0 0 0 0 0 0 +AAAAEYLDTYADGSKNGAATDKLVAALEAC(Carbamidomethyl)GC(Carbamidomethyl)DAAK MGYG000002528_01780 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002528_01780 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4779533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAEYLDTYTDGK MGYG000000080_02732 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000080_02732 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1721321 0 0 0 0 0 0 0 0 0 +AAAAEYLDTYTDGKK MGYG000000080_02732 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,268CP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000080_02732 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7507500 0 0 0 0 0 0 0 0 0 +AAAAGAAAPAAEAK MGYG000001494_00393;MGYG000002447_00580 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Mesosutterella 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4H4X8@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001494_00393 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 344623 0 0 361929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 703273 479344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAGC(Carbamidomethyl)AESAEILK MGYG000002274_02671;MGYG000002545_01451 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002274_02671 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 1226603 1292439 1118791 1444399 0 1585516 1272107 0 0 0 1687198 1437772 1056597 0 1009487 0 1037022 3503426 0 0 0 1333590 4049980 2014819 1076215 0 1241802 4467057 0 1683672 1489119 1479711 1079306 0 1148619 1393794 1114655 1182576 289154 384352 0 381691 0 551062 730122 0 0 0 0 0 618985 0 339966 0 0 715338 0 0 0 269558 912407 635623 412964 0 568788 897104 0 525468 493171 357920 0 0 0 517818 137754 839778 1561643 462804 560524 1176866 0 2110824 1961968 0 0 0 1579247 1436988 1610029 0 1346843 0 1858789 6705260 0 0 0 1105537 6644270 2939503 1570014 1731152 1370593 6357977 0 1791357 1919893 1904277 1051588 0 1935541 1850438 1443856 1443757 1191957 615652 1246058 1303150 0 924511 543361 0 0 0 922817 729102 1550154 0 1042599 0 1036110 4166611 0 0 0 1024350 5479827 913571 656306 1136039 1100291 6006846 0 923771 2550567 1075556 1283969 0 978681 991885 1164587 1081277 0 449880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2647611 0 0 0 474957 2841185 0 1361148 0 0 2452059 0 1094314 0 0 0 0 0 780998 0 337275 +AAAAGC(Carbamidomethyl)PDAADVLEK MGYG000000077_01058 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum soehngenii|m__MGYG000000077 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000077_01058 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAGC(Carbamidomethyl)PDAAEVLEK MGYG000000262_01692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000262_01692 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 631091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAGC(Carbamidomethyl)PDAAEVLEKK MGYG000000262_01692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000262_01692 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 276534 0 0 0 0 0 0 0 0 0 602661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176751 0 0 0 0 0 0 292095 0 0 554441 0 0 0 0 0 0 0 0 0 318956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 205755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1445928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 861260 0 0 0 0 0 0 558374 0 0 619827 0 0 0 0 0 0 0 0 0 469132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 716905 0 1427451 0 0 0 0 589819 +AAAAGC(Carbamidomethyl)PDAK MGYG000000271_02509;MGYG000002517_00959;MGYG000000356_00314;MGYG000000280_02128;MGYG000000389_00578;MGYG000000076_02414;MGYG000000154_00174 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000271_02509 0.14285714285714285 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 1697292 623189 236071 1662113 601167 652274 1564206 657311 1652317 1039266 1764342 981509 860402 1040406 1899235 759213 1237126 2398605 1903933 0 1841225 669345 2277680 788686 1544590 1207026 1951126 2776434 624190 1615966 392937 319705 287664 1996672 708593 1795593 1374186 427357 113679 0 0 0 86722 66141 125480 0 0 0 130442 0 75386 185592 0 0 102129 279397 75671 88154 0 0 641338 64164 130110 0 0 732589 0 47494 0 0 0 111239 0 0 106227 0 445365 97068 0 251784 107867 86886 190359 401116 334459 301797 186205 271159 326863 315499 546126 339618 447290 0 398730 640764 1028858 164179 98564 349755 709850 620122 676445 224335 201240 311795 41964 118593 0 555935 470182 493092 654792 0 3027964 672124 161473 6370509 571410 660899 4644815 2959125 6639542 1092174 661487 818978 555638 2955332 1868120 991410 1832969 407590 1939203 3845323 1586086 190740 0 99301 4466428 3198059 3598909 350862 576893 1514626 253215 628393 176425 1665779 2815971 1652626 4174323 304246 3238727 2183608 1561265 0 1061790 968634 2929412 1137941 2918375 2897515 1839350 1985949 321408 3638388 4461766 752063 2817102 1104421 686708 1879638 2634089 887804 1622895 1244802 2269075 2785247 3473102 912390 557488 1026165 1281222 168488 2642947 1755508 3027923 3646063 3519466 1351611 +AAAAGC(Carbamidomethyl)TESAEILK MGYG000000022_01634;MGYG000002040_01920 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000022_01634 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 260159 509047 552005 0 436038 379527 376507 392837 415236 366122 636916 302791 438460 438276 336591 447206 278711 1632728 291761 0 429113 478224 1739694 348471 354809 350016 324976 1221448 396557 398737 450800 515356 504047 348156 410313 307210 0 280174 781075 678076 814292 716129 736937 673445 819442 791747 899720 1204330 1341677 633984 828370 706258 707305 800526 892584 10816558 403758 797162 612394 603660 12774228 803679 591279 824455 1090767 12244484 632339 477269 712206 683333 769234 771997 789070 883885 988328 791905 1416906 2067722 1458237 1584140 1444593 1842635 1694080 1517083 1416667 2093908 1793227 996843 1530403 1939508 1715468 1575908 2112342 6479260 1858815 1104991 1305672 1743379 7739014 1688848 1866828 1639872 1447288 8031148 1856740 1683219 1704439 1772714 1565038 1660925 1989454 1765471 2073032 2119958 410971 621752 597128 669631 612335 488850 590204 343164 736433 802693 331871 491099 657455 346568 475828 433161 753908 2283600 455329 549495 552038 520844 1679666 345215 601698 408691 497264 2306661 633887 594635 619300 648405 578474 0 671615 462400 439695 612289 929582 796202 1732114 1197351 980616 1244167 1456961 1565944 849149 1508101 976860 955485 1149532 1074795 1112278 1121493 1053716 11068902 1255689 861707 924151 981404 12164596 1256359 1202238 993227 1191670 13261180 1234576 774202 1109189 1096556 1728501 1063096 1212158 1010733 1106161 1859932 +AAAAGCT(Thr->Gln)ESAEILK MGYG000000022_01634;MGYG000002040_01920 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000022_01634 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1044120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAGENEEWSLDYPK MGYG000001364_02910;MGYG000000273_02921;MGYG000001306_00797;MGYG000003693_00002 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1592@1|root,COG1592@2|Bacteria,4NH0J@976|Bacteroidetes,2FNC9@200643|Bacteroidia,4AKRD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 1.0 rbr 1.0 GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001364_02910 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 952457 0 826034 1162029 0 825556 1055910 1299039 1109876 1245217 1173337 1134696 0 1169337 1337558 0 1321930 5068349 0 0 634403 0 6101312 698848 1046107 1115123 1219750 5427749 768347 0 822869 0 797975 0 0 871172 1193266 832741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 673809 0 0 0 0 787195 0 0 0 0 565435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAGENEEWSLDYPR(Arg->Lys) MGYG000000042_01353 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900066445|m__MGYG000000042 1.0 COG1592@1|root,COG1592@2|Bacteria,4NH0J@976|Bacteroidetes,2FNC9@200643|Bacteroidia,4AKRD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 1.0 rbr 1.0 GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01353 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 771964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAGENEEWTQMYK MGYG000000099_00558 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,268QG@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_00558 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478211 0 0 0 0 0 0 771891 0 0 0 0 0 0 670765 0 0 0 0 0 0 0 0 0 0 943969 863981 0 0 0 0 0 0 0 0 0 406097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAGENEEWTTDYPHFADVADQEGFPAIATMYR MGYG000000243_01523;MGYG000004797_00312 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1592@1|root,COG1592@2|Bacteria,4NH0J@976|Bacteroidetes,2FNC9@200643|Bacteroidia,22WSM@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Rubrerythrin 1.0 rbr 1.0 GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01523 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAGWGFDGLADDATAK MGYG000002926_01410 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_01410 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 290334 0 0 0 0 422552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429373 0 0 314515 0 0 0 255539 0 335214 0 0 349111 0 0 568129 0 0 549516 511167 0 204024 0 0 0 0 0 0 0 0 419263 0 0 0 0 0 0 313519 668004 0 0 0 0 0 0 423036 235965 400556 549354 0 930314 0 392729 1157146 0 0 700060 762234 621384 550510 0 763226 0 0 0 0 956124 0 927774 784632 678875 0 0 0 933262 1126183 1224399 0 0 871743 0 0 809484 864254 1302502 520545 1065603 809593 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAIDQK MGYG000002528_02464 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,267YC@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gltA 1.0 - 1.0 1.4.1.13,1.4.1.14 1.0 ko:K00266 1.0 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 1.0 - 1.0 R00093,R00114,R00248 1.0 RC00006,RC00010,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fer4_20,NAD_binding_8,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02464 1.0 glutamate synthase (NADPH). | glutamate synthase (NADH). NADPH-glutamate synthase. | NADH-glutamate synthase. The reaction takes place in the opposite direction.-!-The protein is composed of two subunits, alpha and beta.-!-The alpha subunit is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.4).-!-The beta subunit transfers electrons from the cosubstrate.-!-The NH3 is channeled through a 31 A channel in the active protein.-!-In the absence of the beta subunit, coupling between the two domains of the alpha subunit is compromised and some ammonium can be produced.-!-In the intact alphabeta complex, ammonia production only takes place as part of the overall reaction.-!-Formerly EC 2.6.1.53. | A flavoprotein (FMN).-!-The reaction takes place in the direction of L-glutamate production.-!-The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2). 2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH. | 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K00266:gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] 1.0 none 1.0 0 116320 0 0 0 147573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324626 0 0 0 144458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAIVGGGGGGRPNMAQAGGK MGYG000002989_02299;MGYG000000806_01910 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3XYZ6@572511|Blautia 0.5 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 - 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002989_02299 0.5 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01872:AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 976273 0 0 0 0 0 +AAAAKPEDEKLAK MGYG000000233_02981;MGYG000002445_00877;MGYG000000255_00872 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1788@1|root,COG1788@2|Bacteria,1UYH2@1239|Firmicutes,24CPB@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit 1.0 gctA 1.0 - 1.0 2.8.3.12 1.0 ko:K01039 1.0 ko00643,ko00650,ko01120,map00643,map00650,map01120 1.0 - 1.0 R04000,R05509 1.0 RC00012,RC00131,RC00137 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02981 0.3333333333333333 glutaconate CoA-transferase. - Glutarate, (R)-2-hydroxyglutarate, propenoate and propanoate, but not (Z)-glutaconate, can also act as acceptors. acetyl-CoA + trans-glutaconate = (2E)-glutaconyl-CoA + acetate. 1.0 1.0 1.0 1.0 Styrene degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01039:gctA; glutaconate CoA-transferase, subunit A [EC:2.8.3.12] 1.0 none 1.0 4349954 2231726 3419254 3233979 2084067 2013214 2568785 4455822 2934022 4571421 2254337 2767738 2039628 4047996 3266909 2219038 2666410 2003678 3296806 3511380 3103174 2733083 1352528 1845730 3641241 2603310 3043464 1441540 3261023 2879100 2014932 2937892 1925370 4940828 3663322 2607333 2411691 1680790 3733848 3102914 2582609 5706127 4542456 3126834 4660280 5162780 3473333 5475742 4380500 4065585 4608427 4979749 3960993 3241563 4226342 680959 3656300 3943830 2940957 2682570 738727 3504852 4462522 4037748 4223984 1144246 5285819 4000028 3044588 4641508 3872231 4428034 3616986 4270693 3690824 2440256 1750820 3185068 1913771 2499789 1079231 1717620 1219738 2697527 2505805 2565660 1401902 1525162 0 2268289 2241730 1730008 1946767 1017200 2406227 2264757 1574581 2371025 993802 1749756 2748744 2677316 2883344 1430069 2191334 1887950 1382750 1894376 1891989 3709901 2206739 1828663 2099350 1796548 2443357 2408182 2575568 1920961 1828757 2929177 3009733 3338357 2277880 3724877 2425972 2085736 1806338 2636471 2508490 2613436 2184535 1053664 2586343 2296960 1161882 3308542 304768 3685505 2369430 2355438 3090796 964942 3143886 1867383 2158740 2006179 2699975 3110749 2201888 1732254 0 2434041 615921 846369 907474 1387819 899053 863287 1207871 925613 987567 955400 1671060 1095323 1331879 1274307 878988 882680 714634 515685 758898 577967 809407 1000572 701175 1358035 1329565 1359173 1072413 469076 1237767 557394 1640064 1096431 1696595 1380909 1361035 1255779 1434733 1252131 +AAAAKWGLGNINR MGYG000000236_03540 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0280@1|root,COG0280@2|Bacteria,4NGX5@976|Bacteroidetes,2FMKY@200643|Bacteroidia,4AK60@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625,ko:K13788 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_03540 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00625:pta; phosphate acetyltransferase [EC:2.3.1.8]|K13788:pta; phosphate acetyltransferase [EC:2.3.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2061931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1749988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAALI(Xle->Val)DKDSAVELYAGFGK MGYG000000022_01359 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01359 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 646116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAALID(Asp->Asn)KDSAVEMYAGFGK MGYG000002040_01442;MGYG000002545_00188;MGYG000002274_02567 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002040_01442 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1682368 0 0 0 0 115066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1748946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1542719 0 0 0 0 1210850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 722032 0 0 0 0 354610 0 0 0 0 158904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238558 0 0 0 0 529380 0 0 0 0 0 0 0 0 0 0 +AAAALIDKDSAVE(Glu->Gln)MYAGFGK MGYG000002040_01442;MGYG000002545_00188;MGYG000002274_02567 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002040_01442 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1272669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408126 0 0 0 0 0 0 0 0 0 0 +AAAALIDKDSAVELYAGFGK MGYG000000022_01359 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01359 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116610 0 0 0 0 479876 0 0 0 0 0 0 0 168405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588410 0 0 0 0 592094 0 0 0 0 434387 0 0 0 0 88287 0 0 0 0 0 0 0 621452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 710560 0 0 0 0 897498 0 0 0 0 1064246 0 0 0 0 116915 0 0 0 0 604439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 440541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 932370 0 0 0 0 1090496 0 0 0 0 1972091 0 0 0 0 580998 0 0 0 0 471918 +AAAALIDKDSAVEM(Met->Xle)YAGFGK MGYG000002040_01442;MGYG000002545_00188;MGYG000002274_02567 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002040_01442 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1069986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAALIDKDSAVEMYAGFGK MGYG000002040_01442;MGYG000002545_00188;MGYG000002274_02567 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002040_01442 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 404978 0 0 0 0 0 868416 0 0 0 0 1080866 0 0 0 0 1061863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 960814 0 0 0 0 956260 0 0 0 0 749971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431018 0 0 0 0 0 1117770 0 0 410865 0 1172078 0 0 0 0 1233437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192365 0 0 0 0 0 292816 0 0 0 0 314354 0 0 0 0 290136 0 0 0 0 0 0 0 0 0 0 +AAAAM(Oxidation)EGPVYMR MGYG000000028_00572;MGYG000002528_00836 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Transketolase 1.0 tktB 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000028_00572 0.5 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 957304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599321 0 0 0 0 0 0 0 0 0 +AAAAMEGPVYMR MGYG000000028_00572;MGYG000002528_00836 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Transketolase 1.0 tktB 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000028_00572 0.5 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 996453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6456622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4380046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAMGDEVEIFALPISEGEKR MGYG000000045_01524 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG1440@1|root,COG1440@2|Bacteria 1.0 2|Bacteria 1.0 G 1.0 protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity 1.0 gmuB_2 1.0 - 1.0 2.7.1.196,2.7.1.205 1.0 ko:K02760 1.0 ko00500,ko02060,map00500,map02060 1.0 M00275 1.0 R11170,R11172 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.3.2 1.0 - 1.0 iEC55989_1330.EC55989_1672,iECIAI1_1343.ECIAI1_1550,iECO103_1326.ECO103_1669,iECO111_1330.ECO111_1934,iECO26_1355.ECO26_2139,iECSE_1348.ECSE_1627,iECW_1372.ECW_m1666,iEKO11_1354.EKO11_2279,iWFL_1372.ECW_m1666 1.0 PTS_IIB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000045_01524 1.0 phosphotransferase. | protein-N(pi)-phosphohistidine--D-cellobiose phosphotransferase. N,N'-diacetylchitobiose PTS permease. | D-cellobiose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N,N'-diacetylchitobiose(out) = diacetylchitobiose-6'-phosphate(in) + L-histidyl-[protein]. | D-cellobiose(out) + N(pros)-phospho-L-histidyl-[protein] = 6-phospho- beta-D-glucosyl-(1->4)-D-glucose(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Phosphotransferase system (PTS) 1.0 K02760:celA, chbB; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 9323139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAANIVPN(Deamidated)TTGAAK MGYG000004828_01576;MGYG000002485_02480 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004828_01576 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 658941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492624 0 264702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAANIVPN(Deamidated)TTGAAKAIGLVIPSLKGK MGYG000004828_01576;MGYG000002485_02480 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004828_01576 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410775 0 0 0 0 0 0 0 576440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAANIVPNTTGAAK MGYG000004828_01576;MGYG000002485_02480 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0057@1|root,COG0057@2|Bacteria,378AH@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004828_01576 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3653980 6508843 8687046 0 6147523 11349256 5765418 0 3731639 14146903 10175351 5084645 8314079 4540235 0 12149556 11011687 0 3990925 3046713 5074493 13934807 0 10015308 3904900 3304999 4224987 0 4992437 6565095 9878917 5820264 10386987 3536332 3720629 3804931 3152486 9087550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAPAAAAPVAPTADPVIPK MGYG000000212_01006 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3XYZP@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01006 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1041218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAPAAAGAAAAAEEEKTEFDVILAEAGATK MGYG000003166_01197;MGYG000001300_02635 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_01197 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 2745690 0 0 0 0 0 0 0 0 0 0 0 1788612 0 0 0 7733357 794283 7360445 0 0 0 785323 0 0 0 0 3787309 0 0 0 0 0 0 0 25885579 0 0 5757028 0 0 0 0 0 4649047 15692324 0 0 0 0 12221699 0 0 0 4785464 38336049 9535542 0 0 0 11877629 0 0 4836867 0 24929259 0 0 0 0 27402939 0 0 0 0 0 5162600 0 0 0 0 0 0 3007896 0 0 0 0 0 0 0 0 2048938 5304842 1139226 0 0 0 10516931 0 0 0 0 0 0 0 0 0 0 0 0 10118280 0 0 12393852 0 0 0 0 0 0 35079699 0 0 0 0 0 0 0 0 4151482 0 32850541 0 0 0 26541431 0 0 21313017 0 27989365 0 0 0 0 16163137 0 0 9999411 0 0 4867594 0 0 0 0 0 1262281 0 0 0 0 0 11202413 0 0 0 0 41182975 0 0 0 0 11803711 0 0 0 0 14662710 0 0 0 0 0 +AAAAPAAGGAAAPAEEEKTEFDVILADVGANK MGYG000003921_01314 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_01314 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 173805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31210659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAPAAPAAPK MGYG000003166_01306;MGYG000003899_01745 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_01306 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468637 0 532518 0 0 0 3075871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 868355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAPAVR MGYG000004797_01082 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 2DZSH@1|root,32VHS@2|Bacteria,4NYRA@976|Bacteroidetes,2FRXJ@200643|Bacteroidia,4AT0S@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 to other proteins from the same organism 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01082 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAPVAGGEPVKAPMPGNILDVK MGYG000003891_01453 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_01453 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1460373 0 0 960429 0 1952381 0 0 0 0 1775376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAPVAR MGYG000004482_00849;MGYG000004276_00434 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,2N7T7@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-lipoyl like 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004482_00849 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 183129 0 0 0 0 762190 0 0 0 0 1270506 0 0 0 0 1178094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769484 0 0 0 0 190926 0 0 0 0 703276 0 0 0 0 1142145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116619 0 0 0 0 0 0 0 0 0 465836 0 0 0 0 462172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAQTTDEANK MGYG000003683_00185;MGYG000003683_00184 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,4CZFK@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 E 1.0 ABC transporter, substrate-binding protein, family 5 1.0 dppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00185 0.5 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 165316 0 0 0 0 69240 0 0 101467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119360 0 0 0 0 262897 0 421728 979642 707978 438178 1444013 0 653317 0 0 706291 0 0 0 0 0 0 2055936 0 563335 0 628076 1168046 2581485 0 0 0 3081357 0 0 1924459 0 622566 0 0 0 0 1011023 0 293428 220280 159580 0 104085 0 175461 0 0 145863 0 0 0 0 0 0 0 0 308818 0 212683 77756 0 0 0 0 203741 0 0 85642 0 408268 0 0 0 0 171073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 240953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAQVK MGYG000002105_01537 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__SFJ001|s__SFJ001 sp004555865|m__MGYG000002105 1.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3WG9P@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily 1.0 purB 1.0 - 1.0 4.3.2.2 1.0 ko:K01756 1.0 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 1.0 M00048,M00049 1.0 R01083,R04559 1.0 RC00379,RC00444,RC00445 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADSL_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002105_01537 1.0 adenylosuccinate lyase. succino AMP-lyase. Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5- aminoimidazole. (1) N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate. (2) (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamide + fumarate. 1.0 1.0 1.0 1.0 Purine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01756:purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1398587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAASLEMPLYR MGYG000001255_01646;MGYG000001300_01663 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000001255_01646 0.5 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 774724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAASLEPGDHGTTYGGNPFVC(Carbamidomethyl)AAVSK MGYG000000133_01201 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3XYZW@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 8.87 1.0 argD 1.0 - 1.0 2.6.1.11,2.6.1.17 1.0 ko:K00821 1.0 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00028,M00845 1.0 R02283,R04475 1.0 RC00006,RC00062 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01201 1.0 acetylornithine transaminase. | succinyldiaminopimelate transaminase. succinylornithine aminotransferase. | succinyldiaminopimelate transferase. Also acts on L-ornithine and N(2)-succinyl-L-ornithine. 2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L- glutamate 5-semialdehyde. | 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (S)-2- succinylamino-6-oxoheptanedioate + L-glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00821:argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 699507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692186 0 0 0 0 0 0 0 +AAAATALSAVK MGYG000004769_01749 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 2DBJA@1|root,2Z9JR@2|Bacteria,1VPE5@1239|Firmicutes,4H62X@909932|Negativicutes 1.0 909932|Negativicutes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01749 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1904647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2403233 0 0 0 0 1695681 0 0 0 0 988452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAVAVAAPAAGGEGAAAAEQTEFDVILK MGYG000000254_02576 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Marinifilaceae|g__Odoribacter|s__Odoribacter splanchnicus|m__MGYG000000254 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000254_02576 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAVEGIKK MGYG000002960_01043;MGYG000003697_02080;MGYG000002293_01614;MGYG000002603_00267 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1052@1|root,COG1052@2|Bacteria,4NFDE@976|Bacteroidetes,2FP6R@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 CH 1.0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 - 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002960_01043 0.25 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 257417 0 0 0 0 0 0 0 0 0 0 0 582457 84605 0 0 0 599124 0 0 0 0 62763 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 274929 0 0 0 0 261291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2199503 0 0 500215 0 0 0 0 896482 0 0 0 0 0 0 1274353 0 0 0 1431465 536509 1897429 0 0 0 2261345 0 0 0 0 573639 0 0 0 0 1469852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAVIDKDSAVELYAGFGK MGYG000001300_00243;MGYG000002641_00107;MGYG000002619_00445;MGYG000002223_01488;MGYG000002651_00051 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00243 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 880371 955512 1283749 1657868 345096 680829 926639 488027 1055685 727218 781722 583501 737821 805315 756596 738273 1142582 669824 1063220 823418 417858 742582 614415 796938 735462 872974 853841 461154 0 387323 932325 656952 1074394 1311936 349926 809528 591468 1137728 2031241 1485689 1472204 2184531 1691727 2800191 3397595 1363417 2180791 461440 1551352 2818542 1665590 2443370 2608128 1828308 3206368 543137 2545227 2226067 1014508 1927453 107367 1589033 2545649 2119337 2111771 437018 0 1444671 2522381 2137680 1305736 2110512 834832 1837956 1912899 1901569 475689 489940 364310 564587 482947 363884 581583 640509 495546 349913 794251 545562 646531 500176 553398 523700 258693 478911 312765 0 354502 121500 333584 213763 455883 625080 600290 590251 0 493386 722707 536460 289275 658796 666075 504516 628248 402498 1038590 1572922 1676937 991165 1226919 1522808 1965822 575889 1377578 745532 1254250 1383901 1840503 1516895 1110506 1239534 1219825 562320 1330135 1145209 1521096 1936035 987098 1614373 1281741 1213132 980831 615031 0 1452776 1788681 1545250 1331195 1521277 480624 1029582 1521022 1631822 672980 506130 509914 863453 0 256647 826234 471701 307911 692814 533340 289095 327854 615860 412952 547103 376828 0 153114 198363 968272 223379 0 466769 754674 549981 443976 0 0 0 283977 325996 0 611223 227295 565584 372778 315411 +AAAAVLGWER MGYG000004735_02276 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 S1 RNA binding domain protein 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_02276 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 329707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1527082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAYLDIPLYR MGYG000001346_02829;MGYG000002717_02775;MGYG000001780_02258;MGYG000001661_02794;MGYG000003681_01100;MGYG000002455_05125 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000001346_02829 0.16666666666666666 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 1002390 748883 808595 913356 587944 729399 1105329 1104395 1069848 1010415 1140835 1592671 0 915646 0 763481 870157 0 1030589 872444 966342 770109 0 879258 0 882769 813688 0 875288 1433848 807517 808880 796972 1209721 1080821 991526 1024527 703023 823831 1328123 1162189 1563316 1918707 1660790 975132 1438571 933978 1280996 1405094 4069542 0 1523206 0 1486372 1240745 0 931868 1157380 1440049 2164407 0 1332593 0 1271031 1154661 0 1253109 1447538 1299820 1764750 1434008 1416186 1115498 930162 866789 1312753 1351273 904687 1264178 771150 1388145 1230703 1424896 1673677 1041858 1206129 1579985 2111429 0 1181405 0 1338812 654123 0 1084840 1255512 1172971 1039620 0 1201010 0 1037064 0 0 1155624 1409868 1295376 946933 1009487 806507 1181177 859376 911030 1124182 864096 588861 1100332 751802 897654 786292 745689 917098 814169 691541 846304 1431425 0 724209 0 786285 645249 0 839863 692266 975462 1033183 0 0 0 981751 941819 0 832670 1158353 608206 772121 1050513 1093425 992761 850880 745225 707640 460107 493647 435317 770259 1212086 791657 475985 936800 759473 502336 2196650 992475 0 426823 0 225738 567780 0 280634 673005 450532 366690 0 710775 0 648496 410295 0 638847 1079627 461874 768875 398632 1007546 797481 312579 718923 552611 +AAAAYLDV(Val->Xle)PLYR MGYG000001313_02613;MGYG000000224_01011;MGYG000000105_02944 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000001313_02613 0.3333333333333333 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1091076 0 0 0 0 0 0 0 0 0 1320826 0 1315964 0 1236466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 831998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAYLDVPLYR MGYG000001313_02613;MGYG000000224_01011;MGYG000000105_02944 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000001313_02613 0.3333333333333333 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 255791 0 0 0 0 168203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300886 0 0 0 0 0 504873 0 0 0 255302 0 0 192372 0 0 0 0 1735472 1121922 0 0 0 0 1838820 2363617 0 1776064 0 1719572 0 0 1510544 998799 1224222 0 0 1404089 1786239 0 0 0 1678446 1496067 1365410 0 1786032 0 1784762 0 0 3525905 1518376 0 1448036 0 461111 387367 0 0 0 0 343245 465376 0 269511 0 266550 0 0 427282 642406 306233 0 0 339925 607602 0 0 0 544782 277100 459174 0 258851 0 147885 0 0 837972 482187 0 497571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAAYLNIPLYR MGYG000001364_02911 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius|m__MGYG000001364 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000001364_02911 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 700116 0 0 0 0 0 0 0 3805746 0 0 0 0 5950170 0 0 0 0 3682429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180927 0 0 0 0 379479 0 0 0 0 387661 0 0 0 0 0 0 0 0 0 0 +AAAAYVGTVIAK MGYG000000179_04584;MGYG000000198_04903 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,2206V@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_04584 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 1229683 0 0 0 0 0 0 0 618243 363342 0 0 0 0 545955 0 0 0 307822 825780 874708 0 0 0 340683 670459 793412 0 0 616262 0 0 0 0 0 0 813675 0 968253 0 217873 0 0 0 0 846403 834638 1092782 0 472803 0 0 753164 0 412604 0 543596 959794 638694 0 0 0 592087 944401 1027228 0 0 461940 231744 256802 346636 0 0 0 849691 281669 1171819 0 381954 0 0 0 0 692712 990899 843451 0 505595 0 0 974308 0 772728 0 740499 1008357 1348208 0 0 0 165050 786263 1114059 0 0 1283806 401321 453100 624493 0 0 0 788400 694333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3477086 0 1295229 0 0 0 0 2397993 2071621 2162518 0 1767396 0 0 3051309 0 2069486 0 2217831 3145654 2639245 0 0 0 2001006 2564055 2992762 0 0 1744230 1150638 973770 1275481 0 0 0 1583718 1073549 +AAAC(Carbamidomethyl)EAVGR MGYG000003291_01608;MGYG000003166_00738;MGYG000001300_02373;MGYG000000022_01425 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3WK2P@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 - 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003291_01608 0.25 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02110:ATPF0C, atpE; F-type H+-transporting ATPase subunit c 1.0 none 1.0 0 0 0 0 0 0 0 0 0 178244 0 0 0 508594 250664 0 0 0 158109 277165 0 0 186448 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217570 270704 0 0 0 0 0 0 105104 0 0 310846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115401 385098 490769 0 0 156782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1376516 1289871 0 1198597 1258997 1404271 0 0 1134988 0 0 1076714 1312689 896343 0 1372258 1494410 1217829 1942602 0 1693741 370222 2947485 746076 0 0 3925159 955315 1080372 2210572 597832 1180394 0 0 0 0 2236112 0 0 0 0 226867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380170 0 319641 0 0 0 0 0 0 0 0 +AAAC(Carbamidomethyl)ESFGYNEDAIVSSDVIGMR MGYG000000198_04065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04065 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 776023 0 0 819883 0 275591 0 0 0 0 0 0 0 0 325434 0 0 0 483913 847248 0 324569 0 201158 0 696240 513407 0 1168391 1028266 0 0 0 0 0 637875 696263 0 267274 0 0 192762 0 0 0 0 0 0 0 0 0 0 323435 0 0 0 0 228481 0 0 0 0 0 348007 267080 0 282524 0 0 0 0 0 0 206340 228609 0 767078 0 0 401246 0 0 0 0 0 0 0 0 0 0 609808 0 0 0 319130 616139 0 287345 0 0 0 796345 660718 0 707681 671373 0 0 0 0 0 654540 590833 0 0 0 0 258284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106341 379940 0 0 0 0 0 679795 1479195 0 174298 0 0 124319 0 705525 0 0 0 0 0 0 0 0 170365 0 0 0 1999059 127249 0 4853349 0 264688 0 169417 16699150 0 3694606 0 0 0 0 0 0 238802 650295 0 +AAAC(Carbamidomethyl)FLIR MGYG000002753_00171 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-103|s__|m__MGYG000002753 1.0 COG4716@1|root,COG4716@2|Bacteria,2GKZ8@201174|Actinobacteria,4CYZK@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 S 1.0 MCRA family 1.0 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002753_00171 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 - 1.0 K10254:ohyA, sph; oleate hydratase [EC:4.2.1.53] 1.0 none 1.0 700362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 779321 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456771 0 0 0 0 0 0 0 0 0 0 408665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAC(Carbamidomethyl)FLVR MGYG000004785_01095;MGYG000000231_02045;MGYG000004733_00873;MGYG000000251_00145;MGYG000000249_02121;MGYG000002186_00911;MGYG000000242_03073;MGYG000000216_00347;MGYG000000212_00918;MGYG000001338_00189;MGYG000000187_00790;MGYG000001698_00562;MGYG000002517_00467;MGYG000000133_01077;MGYG000001185_00828;MGYG000000271_02405 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia 0.5 186801|Clostridia 1.0 S 1.0 Myosin-crossreactive antigen 0.625 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004785_01095 0.0625 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 - 1.0 K10254:ohyA, sph; oleate hydratase [EC:4.2.1.53] 1.0 none 1.0 941030 0 1268165 590772 1720620 1308942 0 1103003 0 0 2341389 0 1461486 864493 0 1548335 0 0 0 0 0 1222108 0 597658 1211258 692366 0 0 826137 0 708616 1238920 796641 0 133393 0 490149 988126 345623 0 413698 210661 0 0 0 419381 0 0 0 0 0 259218 0 0 0 0 0 0 0 0 0 0 99180 133036 0 0 408143 0 0 0 184667 0 285246 0 171024 0 530745 0 848817 609287 371433 528889 0 526314 0 0 525243 0 852154 680150 0 776638 0 0 0 0 0 757703 0 261224 622971 569857 0 0 643206 0 564623 725877 905704 0 471362 0 123550 727442 836724 0 748541 964752 1125777 803326 0 781548 0 0 685301 0 574683 844511 0 1324301 0 0 0 0 0 912165 0 478980 529333 0 0 0 1010920 0 1965840 974175 1006919 0 771931 0 804335 1025943 390418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527832 441995 449062 0 0 0 0 0 0 0 0 0 0 0 0 +AAAC(Carbamidomethyl)GGVTTIFDYPVQHK MGYG000002528_01045 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 PFAM amidohydrolase 1.0 hydA_1 1.0 - 1.0 3.5.2.2 1.0 ko:K01464 1.0 ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100 1.0 M00046 1.0 R02269,R03055,R08227 1.0 RC00632,RC00680 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_1,Urease_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01045 1.0 dihydropyrimidinase. hydantoinase. Also acts on dihydrothymine and hydantoin. 5,6-dihydrouracil + H2O = 3-(carbamoylamino)propanoate + H(+). 1.0 1.0 1.0 1.0 Pyrimidine metabolism|beta-Alanine metabolism|Pantothenate and CoA biosynthesis|Drug metabolism - other enzymes|Metabolic pathways 1.0 K01464:DPYS, dht, hydA; dihydropyrimidinase [EC:3.5.2.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 197885 0 433868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110964 0 455204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 425256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1144700 0 466963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAC(Carbamidomethyl)NIVPN(Deamidated)STGAAK MGYG000003355_00996;MGYG000001299_00204 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 0.5 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003355_00996 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 648499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1604786 0 0 0 0 452263 +AAAC(Carbamidomethyl)NIVPNSTGAAK MGYG000003355_00996;MGYG000001299_00204 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 0.5 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003355_00996 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 518381 0 0 0 0 361133 0 0 0 208012 0 0 0 0 0 0 0 0 474010 286330 168225 0 0 0 0 0 0 0 0 0 0 0 0 272332 319564 289581 0 2823116 2038721 840165 2625583 1180276 1587704 2715976 3037177 2153800 2198368 978822 1101017 0 1730879 0 0 0 0 1407591 2471653 1705563 970382 0 2353203 0 2046653 2724685 0 2861304 0 1952416 0 931931 2849235 3155158 2655990 2527159 979686 742668 917715 392548 617603 0 364718 607868 890367 339903 634186 464258 593443 0 553185 0 0 0 0 1108494 880713 556762 788549 0 330574 0 713534 857686 0 751233 0 311356 0 574281 1022099 905034 565317 691313 501509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1580495 2623077 9855997 2129900 632814 12685454 3549151 2461632 1715703 2759881 2383801 1811216 0 3404852 0 0 0 0 1668801 554020 2318346 10798161 0 12097834 0 2406635 1974263 0 3572205 0 4616534 0 20059372 2429093 2008920 2435272 1212585 6509163 +AAAC(Cys->Ser)ESFGYNEDAIVSSDVIGMR MGYG000000198_04065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04065 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 907449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAACESFGYNED(Asp->Trp)AIVSSDVIGMR MGYG000000198_04065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04065 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 1348023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 688293 0 0 0 0 1189551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 810487 0 0 0 0 807485 0 0 394643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225168 0 0 0 0 0 +AAACNI(Xle->Tyr)VPNSTGAAK MGYG000003355_00996;MGYG000001299_00204 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 0.5 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003355_00996 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 602390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 526875 0 0 0 0 597772 0 0 698516 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663654 0 0 0 0 1072768 0 0 630798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1758850 0 0 0 0 1013277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3952983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3301715 0 0 0 0 2919300 +AAADAAKTEADKAVAEASAVK MGYG000002455_05079 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG3883@1|root,COG3883@2|Bacteria,4P07U@976|Bacteroidetes,2FN9Y@200643|Bacteroidia,4APBT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 nuclear chromosome segregation 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Collagen,DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_05079 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 737248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5834560 0 0 0 0 +AAADAAVQFISGEEVDAK MGYG000000242_00891 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,21Z0Q@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 K 1.0 PFAM regulatory protein GntR HTH 1.0 - 1.0 - 1.0 - 1.0 ko:K00375 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2,GntR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000242_00891 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K00375:K00375; GntR family transcriptional regulator / MocR family aminotransferase 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1098607 0 0 0 0 420342 0 0 0 0 347514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239125 0 0 0 0 0 0 0 0 0 195165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 693574 0 0 0 0 745094 0 0 0 0 1042929 0 0 0 0 0 0 0 0 0 0 +AAADALFAAGK MGYG000003166_02177;MGYG000001300_01133;MGYG000003291_01773 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3WHFT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner 1.0 valS 1.0 - 1.0 6.1.1.9 1.0 ko:K01873 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03665 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 GH5_11 1.0 MGYG000003166_02177 0.3333333333333333 valine--tRNA ligase. valyl-tRNA synthetase. - ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01873:VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9] 1.0 none 1.0 120523 308296 329862 0 0 250502 0 0 114785 0 471239 198626 0 0 0 0 0 0 551068 428970 0 122841 0 198039 0 334019 0 0 0 0 0 315353 0 0 0 0 121043 150712 647041 899321 888373 0 0 912577 0 0 752475 0 526469 962856 0 0 0 0 0 0 937449 985749 0 685907 0 1082402 0 509654 0 0 0 0 965141 756639 927506 0 0 0 686870 723191 303718 295869 428646 0 0 291627 0 0 295250 0 516952 535222 0 0 0 0 0 0 346092 389000 0 118215 0 173679 0 261532 0 0 0 0 251302 258767 119352 0 0 0 206631 314393 365037 299836 879639 0 0 647823 0 0 327356 0 588459 612145 0 0 0 0 0 0 238738 376392 0 646440 0 685761 0 374560 0 0 0 0 672545 505650 771621 0 0 0 300858 721687 467182 550359 309746 0 0 735176 0 0 411407 0 302084 384113 0 0 0 0 0 0 581354 512761 0 475179 0 923355 0 527598 0 0 0 0 269554 322728 375658 0 0 0 508833 1687923 +AAADAMQDGDVILLQNTR MGYG000000080_03114 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_03114 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3352533 0 0 0 0 0 0 0 0 0 +AAADDAETIC(Carbamidomethyl)GEDYWPLPSYSK MGYG000001300_00352;MGYG000002040_00733;MGYG000000022_01091 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 0.6666666666666666 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00352 0.3333333333333333 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Glyoxylate and dicarboxylate metabolism|Nitrogen metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Biosynthesis of amino acids|Two-component system|Necroptosis|Glutamatergic synapse|GABAergic synapse 1.0 K01915:glnA, GLUL; glutamine synthetase [EC:6.3.1.2] 1.0 none 1.0 0 0 566356 264383 0 0 0 0 257227 0 0 0 0 485334 0 0 0 0 612945 325970 0 0 0 0 0 400586 232982 527561 0 0 0 0 455615 0 0 0 272441 311637 536736 0 590965 656978 0 0 768765 0 689226 0 0 713632 0 759021 0 0 646481 877488 874675 797944 0 0 1092504 0 956550 840109 562150 881572 0 0 0 0 0 0 0 0 0 421724 0 0 0 0 0 0 224144 0 0 0 0 0 0 291863 0 0 0 272877 127476 203459 0 0 0 0 0 0 0 425342 0 0 0 0 0 0 0 0 0 161358 500048 0 745928 453646 0 0 619238 0 520939 0 0 529200 0 563305 0 0 587609 248095 575684 503654 0 0 243491 0 435904 602181 466355 381693 0 0 0 0 531717 0 0 0 531792 465862 0 0 0 0 0 0 84190 0 0 0 0 0 0 0 0 0 0 472891 0 0 0 0 544388 0 0 0 0 530754 0 0 0 0 0 0 0 0 0 179092 +AAADDAETLC(Carbamidomethyl)GEDYWPLPSYSK MGYG000003291_00218;MGYG000003899_00843 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 1.0 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003291_00218 0.5 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Glyoxylate and dicarboxylate metabolism|Nitrogen metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Biosynthesis of amino acids|Two-component system|Necroptosis|Glutamatergic synapse|GABAergic synapse 1.0 K01915:glnA, GLUL; glutamine synthetase [EC:6.3.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303924 0 0 0 0 0 0 0 0 0 0 482564 0 0 0 0 0 0 0 0 783219 0 0 0 0 0 0 471288 0 459932 0 0 0 0 0 0 0 0 524185 0 0 546139 733428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 624471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADEAAAPAVVEEGGLHK MGYG000003693_02590 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_02590 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 828560 0 0 0 0 1847266 0 0 0 0 1112199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADEEKEPAKK MGYG000000280_00174 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__AM51-8|s__AM51-8 sp003478275|m__MGYG000000280 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,27I7R@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_00174 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADEHHVQYEER MGYG000000133_02652 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,27I57@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 tRNA synthetases class II (D, K and N) 1.0 lysS 1.0 - 1.0 6.1.1.6 1.0 ko:K04567 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03658 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DUF2156,tRNA-synt_2,tRNA-synt_2_TM,tRNA_anti-codon,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02652 1.0 lysine--tRNA ligase. lysyl-tRNA synthetase. - ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K04567:KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517531 0 757192 0 0 0 949630 0 0 755942 0 647623 0 0 0 0 0 0 0 0 1250022 0 0 0 0 753286 0 0 0 0 0 0 1691749 0 0 1261687 580546 751737 +AAADEWDER MGYG000002506_00360 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 291QA@1|root,2ZPAE@2|Bacteria,1RI2H@1224|Proteobacteria,1S689@1236|Gammaproteobacteria,3XPRZ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 MsyB protein 1.0 msyB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 - 1.0 ko:K12147 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 MsyB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00360 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K12147:msyB; acidic protein MsyB 1.0 none 1.0 0 0 0 0 0 773017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 744328 0 1104428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 514041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604187 0 363744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 548383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227751 0 483717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADGC(Carbamidomethyl)PTAPEVLAK MGYG000002552_01042 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp000436535|m__MGYG000002552 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002552_01042 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 614727 0 0 0 0 463504 0 0 0 0 579609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1038724 0 0 0 0 925383 0 0 0 0 1143372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 757789 0 0 0 0 480659 0 0 0 0 385134 0 0 0 0 0 0 0 0 0 0 +AAADKAGVNVK MGYG000001060_01648 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister hominis|m__MGYG000001060 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,4H3VQ@909932|Negativicutes 1.0 909932|Negativicutes 1.0 G 1.0 sugar-binding domain protein 1.0 rbsB 1.0 - 1.0 - 1.0 ko:K10439,ko:K17213 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212,M00593 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001060_01648 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein|K17213:K17213; inositol transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 868595 0 0 0 0 394035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADKAVADAK MGYG000002478_01081 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01081 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 5348952 4662430 5108485 9597658 7817546 6856743 6377108 0 6645392 6068871 0 6927671 10165920 4582508 0 13336360 9317951 9587995 9359437 6625683 5490413 0 6323513 5123369 5701862 5588351 6649266 8360777 5507132 7941239 0 7119878 4412900 0 5739340 6864245 5423283 4659211 215486 0 0 228927 116920 0 0 0 0 0 0 0 88473 195051 0 242537 286315 108565 0 0 0 239664 0 0 128358 0 0 0 0 216819 0 287261 144440 0 71161 159096 156849 52579 803249 1541333 1082627 1422775 1014341 900509 401567 0 812251 0 0 773551 1671895 972558 0 1342577 1040696 319811 1255203 1136490 1316537 1097951 642422 745656 889536 1085438 1284130 1677821 1009192 829102 0 834285 767472 0 1770821 1367808 1404985 1043639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325272 147558 102647 220073 220472 172671 119225 0 288355 167457 0 150274 348423 727422 0 255876 221251 547813 263105 265527 767901 194513 395347 289986 408611 305051 203335 199276 208368 0 0 190378 86520 0 400330 278121 119262 312607 +AAADKAVADAKAEAIK MGYG000002478_01081 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01081 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 3379548 5866319 6618855 4120322 8709420 5182787 2580135 0 3261236 4013850 0 0 10031994 4349659 0 9232052 5914018 5344374 5677653 3871936 3873754 0 3296506 4048154 3915497 4182576 2995089 3286894 2758432 4340221 0 7051009 6358811 0 5406424 0 3843796 5826132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 866905 1581975 1236289 1063424 1376097 964559 0 0 0 1184594 0 0 2324207 786511 0 1656352 82172 110978 1055990 914198 681854 1040881 78882 697427 0 722875 950710 0 914156 738796 0 1164936 1065460 0 841745 0 89544 622313 0 0 0 0 0 0 0 0 0 0 0 0 129837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 55095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374460 0 0 0 0 0 0 0 359944 0 0 0 0 313193 0 0 0 0 0 58583 0 0 0 0 0 0 0 0 0 0 +AAADKAVAE(Glu->Asp)AK MGYG000002560_04324 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp902388365|m__MGYG000002560 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002560_04324 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1185512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADKFLETK MGYG000002492_01331;MGYG000000398_00301 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002492_01331 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 135008 164266 125778 123948 212687 117677 47161 149188 131999 0 224405 233736 253819 85642 135845 182287 0 538726 72017 100593 163296 134064 325249 0 149341 180694 84139 398822 0 100704 84609 272095 0 62276 152637 74424 152411 165580 793162 698953 3790394 822806 1759017 512295 1038244 736699 926745 0 1683710 0 1400175 652128 611837 1220240 0 6905602 545077 806877 987568 418710 4307091 550199 728759 733278 749168 5918432 0 724363 2075897 1093246 0 858270 794016 876981 0 4012417 0 1966463 9303990 1628222 3420056 2119321 2014300 1770349 1990994 0 0 2194859 3717223 1880746 2144879 4323668 0 2089054 1846644 1846074 1740441 0 0 0 0 1925079 0 0 0 2240617 3547620 0 8718200 2361711 2211292 1560841 0 0 295620 124307 0 708799 98383 0 81909 0 518311 0 452265 227871 148274 0 275156 181524 0 301466 218896 0 165484 0 139160 76677 101622 257734 0 99447 0 83455 150623 65821 78158 229051 0 301903 0 551500 0 429417 513910 96592 97022 0 84468 0 72654 0 133594 0 0 575516 103476 231139 0 0 183436 74018 146727 0 140979 124701 144546 146699 484105 132869 0 0 1168869 134548 0 101025 0 131817 0 0 +AAADKFLETKDDTK MGYG000002492_01331;MGYG000000398_00301 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002492_01331 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 210951 0 497769 310936 228630 0 0 0 0 429648 526440 423907 296168 0 392389 221218 0 769423 0 0 0 406741 567031 214765 587167 317540 0 578879 0 331033 0 0 202174 0 384558 0 0 321055 429141 214836 1035902 353377 1162170 438524 0 248505 0 380894 1017564 323701 656298 308876 260178 457292 0 1071653 211553 0 0 243982 486909 434874 282954 321058 0 1196801 0 325774 437397 0 2392784 409221 444902 0 395807 1228401 1776975 1696822 7225770 1548795 2636353 1319595 0 1764245 0 1707473 2469336 2125611 3333848 1518205 1494347 3439986 1527710 1220105 1735757 0 0 1393596 1927319 1304353 1688038 1783135 0 2510570 0 1808178 2719123 0 5932657 1762331 1999002 0 1592270 6412781 0 0 168207 0 0 0 0 0 0 0 170016 0 0 0 274483 0 0 0 0 0 0 0 221130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163794 0 0 0 0 0 0 0 0 0 0 350597 0 0 0 0 0 0 217871 0 0 0 0 0 0 0 0 +AAADKFLETKDDTKANVEPTTALIAELEK MGYG000002492_01331;MGYG000000398_00301 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002492_01331 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1397043 0 0 0 0 0 0 0 0 0 920326 0 0 881673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1739914 0 0 0 0 1241381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADLLVLAYHR MGYG000003695_00289;MGYG000004558_01494;MGYG000000249_00466;MGYG000003581_01363;MGYG000002279_00355;MGYG000002992_01118;MGYG000001338_01660;MGYG000000038_02127;MGYG000000184_00391 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3WGGW@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 1.0 M 1.0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily 1.0 rfbB 1.0 - 1.0 4.2.1.46 1.0 ko:K01710 1.0 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 1.0 M00793 1.0 R06513 1.0 RC00402 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000003695_00289 0.1111111111111111 dTDP-glucose 4,6-dehydratase. - - dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O. 1.0 1.0 1.0 1.0 Streptomycin biosynthesis|Polyketide sugar unit biosynthesis|Acarbose and validamycin biosynthesis|Biosynthesis of vancomycin group antibiotics 1.0 K01710:rfbB, rmlB, rffG; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] 1.0 none 1.0 748334 440342 415592 405102 269376 479775 0 858522 499561 354595 672616 0 416769 408837 0 373192 760174 187884 1026264 769964 554429 525295 73016 276560 0 561056 541294 186248 245765 375995 0 447166 297131 531869 668527 295661 424566 330446 350022 491697 471019 422816 1563365 204130 0 400461 483946 433672 825875 0 526451 341667 526943 312051 143523 1126279 257679 519010 408914 239144 512978 339343 485613 352517 304639 698666 285809 268642 0 860702 494086 408469 395954 400179 320333 786852 805070 732674 365600 967335 360561 288435 0 787653 345704 658702 451767 0 577850 764529 1056113 600100 551977 150243 1249458 1161410 671896 565731 332713 409951 1131215 980296 1170131 411645 714638 749813 0 650600 611383 1021020 1307945 423980 773268 460771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADLNYTLR MGYG000002438_02346 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG3015@1|root,COG3015@2|Bacteria,4P5SI@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 MP 1.0 NlpE N-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NlpE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02346 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1275302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1064042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2003698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADLQLQGVPAMFVN(Deamidated)GK MGYG000002494_01991;MGYG000002534_04778 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Thiol disulfide interchange protein 1.0 dsbA 1.0 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0016853,GO:0016860,GO:0016864,GO:0042597,GO:0044464,GO:0140096 1.0 - 1.0 ko:K03673 1.0 ko01503,map01503 1.0 M00728 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03110 1.0 - 1.0 - 1.0 - 1.0 DSBA,Thioredoxin,Thioredoxin_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01991 0.5 - - - - 1.0 1.0 1.0 1.0 Cationic antimicrobial peptide (CAMP) resistance 1.0 K03673:dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 643688 1068823 1009827 601595 998361 1766710 828662 0 0 1047102 0 733030 0 1155983 0 0 1537569 0 1216809 638619 0 1693200 0 1332391 1252623 456955 740700 0 1897019 1183107 447314 935932 1162151 0 0 0 676002 620504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2937786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADLQLQGVPAMFVNGK MGYG000002494_01991;MGYG000002534_04778 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1651@1|root,COG1651@2|Bacteria,1RGWH@1224|Proteobacteria,1S5WA@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Thiol disulfide interchange protein 1.0 dsbA 1.0 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0009987,GO:0016853,GO:0016860,GO:0016864,GO:0042597,GO:0044464,GO:0140096 1.0 - 1.0 ko:K03673 1.0 ko01503,map01503 1.0 M00728 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03110 1.0 - 1.0 - 1.0 - 1.0 DSBA,Thioredoxin,Thioredoxin_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01991 0.5 - - - - 1.0 1.0 1.0 1.0 Cationic antimicrobial peptide (CAMP) resistance 1.0 K03673:dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15] 1.0 none 1.0 0 371983 0 255685 0 375852 0 0 0 241148 0 0 0 0 0 0 0 0 202768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207754 0 852159 732667 582370 0 857400 644775 0 0 801337 0 0 0 0 0 0 784668 0 723002 0 0 1195851 0 884414 0 0 0 0 928415 0 0 0 598524 0 0 0 0 840813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359190 0 307081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADPFAELYK MGYG000002528_02607 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG5263@1|root,COG5263@2|Bacteria 1.0 2|Bacteria 1.0 S 1.0 dextransucrase activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Big_2,Big_3,Big_4,CHAP,CW_binding_1,DUF5011,Esterase,Glyco_hydro_70,LRR_5,Lectin_C,Lyase_8,Lyase_8_C,Lyase_8_N,SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02607 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 264705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193512 0 0 266538 0 0 0 0 0 0 0 1316711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 758850 0 0 0 0 0 0 0 385377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1911495 0 0 239968 0 0 0 0 0 0 0 704246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1969498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADTAAAETK MGYG000000074_01658 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG2152@1|root,COG2152@2|Bacteria,4NGDZ@976|Bacteroidetes,2FPFW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 COG NOG16664 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1080 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01658 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 110547 95395 237647 386144 513161 576918 0 391161 356536 511735 416953 390438 716189 0 725214 145310 463026 0 376884 498156 315083 0 0 136360 748876 329983 351345 0 268342 225747 331600 747214 242961 0 375190 466836 417056 383518 1597864 1255221 2096595 2677601 2028781 2001605 0 2191712 1970566 2008101 1685155 2494326 1401308 0 2111024 1535113 2055704 0 2621110 2673470 1975906 2082519 0 1874388 2207663 2006625 2196035 0 2123387 2666517 1670237 2174586 1768584 0 1510574 1224512 1922233 1364044 792897 0 432707 1478091 164977 877126 0 1209077 257417 935483 443573 650984 746166 0 1031125 921005 743476 0 216170 1097034 773768 1592451 0 639617 869514 1064416 1134664 0 555264 624491 297203 915036 727780 0 1110508 414181 786618 434077 1885301 1662597 1535469 0 1596386 1954103 0 1966438 2404771 1970293 1159625 1657440 1292489 0 1778154 2012731 1903425 0 2669740 2434200 902013 1838650 0 1668320 2787467 2985131 2174445 0 2163660 1916139 1295485 1660954 1629853 0 2076331 1047728 1924512 1562357 3166602 3532385 2835613 5049615 4726534 3590342 0 2397661 3724936 3388354 3082192 3136856 6220237 0 3320602 3300148 2928532 0 5848387 4637752 2987010 3481129 0 4914127 4031788 6889888 3637558 0 3301629 5020805 3940082 3596895 3592476 0 6941527 5630711 5765625 4492461 +AAADTESEKLGTLDQGTVVTR MGYG000002517_01751 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG3103@1|root,COG3103@2|Bacteria,COG4991@2|Bacteria,1USNV@1239|Firmicutes,24DRI@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 Bacterial SH3 domain homologues 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SH3_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01751 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235644 0 0 1111418 0 0 0 1395287 1135048 0 0 0 0 1302083 1447111 0 0 0 0 0 0 0 0 0 1254363 1052897 1168945 0 0 919764 0 0 0 1106287 1235183 894021 1472344 0 651666 0 0 0 0 0 0 504728 844624 0 0 0 0 862147 1072345 0 0 0 0 0 0 0 0 0 586097 635461 805575 0 0 734718 0 0 0 593758 665265 748807 1466034 0 +AAADVGAPYIEIHTGC(Carbamidomethyl)YADAK MGYG000002494_04100;MGYG000002534_03650 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0854@1|root,COG0854@2|Bacteria,1MU9W@1224|Proteobacteria,1RMS5@1236|Gammaproteobacteria,3XP85@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate 1.0 pdxJ 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.0 2.6.99.2 1.0 ko:K03474 1.0 ko00750,ko01100,map00750,map01100 1.0 M00124 1.0 R05838 1.0 RC01476 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iAF1260.b2564,iB21_1397.B21_02422,iBWG_1329.BWG_2328,iEC55989_1330.EC55989_2852,iECBD_1354.ECBD_1117,iECB_1328.ECB_02458,iECDH10B_1368.ECDH10B_2732,iECDH1ME8569_1439.ECDH1ME8569_2491,iECD_1391.ECD_02458,iECH74115_1262.ECH74115_3800,iECIAI1_1343.ECIAI1_2675,iECO103_1326.ECO103_3142,iECO111_1330.ECO111_3290,iECO26_1355.ECO26_3611,iECSE_1348.ECSE_2852,iECSP_1301.ECSP_3509,iECW_1372.ECW_m2792,iECs_1301.ECs3430,iEKO11_1354.EKO11_1169,iEcDH1_1363.EcDH1_1104,iEcE24377_1341.EcE24377A_2850,iEcHS_1320.EcHS_A2719,iEcolC_1368.EcolC_1113,iG2583_1286.G2583_3145,iJO1366.b2564,iJR904.b2564,iWFL_1372.ECW_m2792,iY75_1357.Y75_RS13390 1.0 PdxJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04100 0.5 pyridoxine 5'-phosphate synthase. pyridoxine 5-phosphate phospho lyase. In Escherichia coli, the cofactor pyridoxal 5'-phosphate is synthesized de novo by a pathway that involves EC 1.2.1.72, EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5.-!-1-Deoxy-D-xylulose cannot replace 1-deoxy-D-xylulose 5-phosphate as a substrate. 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate. 1.0 1.0 1.0 1.0 Vitamin B6 metabolism|Metabolic pathways 1.0 K03474:pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432911 0 0 0 781939 0 0 0 0 0 0 0 0 0 0 630634 0 0 0 0 964357 0 464039 572977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADVYM(Oxidation)FAN(Deamidated)DQLEPLIK MGYG000002492_00484 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC transporter, solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00484 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K15770:cycB, ganO, mdxE; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADVYM(Oxidation)FANDQLEPLIK MGYG000002492_00484 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC transporter, solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00484 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K15770:cycB, ganO, mdxE; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADVYMFANDQLEPLIK MGYG000002492_00484 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC transporter, solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00484 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K15770:cycB, ganO, mdxE; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 539035 0 0 0 0 0 0 0 0 0 499756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134425342 0 0 0 0 12346821 0 0 0 0 130719313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20486343 0 0 0 0 53937645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3872040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADYFGLPLYR MGYG000001302.1_00358 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,22U9M@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000001302.1_00358 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 126441 0 0 0 0 302288 0 0 0 0 266431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585538 0 0 0 0 446859 0 0 0 0 491586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 916179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAADYFGM(Oxidation)PLYR MGYG000001420_02263;MGYG000002203_01744;MGYG000002082_02009;MGYG000000003_00610;MGYG000000074_00749 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,22U9M@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000001420_02263 0.2 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 504970 0 0 0 272289 0 0 0 237727 0 0 0 316546 0 0 0 0 0 0 409102 0 0 0 0 0 371885 0 0 0 0 0 0 0 0 0 0 238386 0 0 0 0 0 0 0 0 0 660862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139528 0 0 0 0 0 0 0 0 0 0 186375 0 0 0 0 0 242631 0 0 0 245359 0 0 0 247907 0 0 0 0 0 0 298521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 510074 0 222037 0 0 0 817956 0 0 0 419117 0 0 0 555396 0 0 0 0 0 0 299141 0 0 0 0 0 455012 0 0 0 0 0 0 0 0 0 0 364314 0 637458 0 0 0 683916 0 0 0 893343 0 0 0 1124551 0 0 0 0 0 0 1229153 0 0 0 0 0 815897 0 0 0 0 0 0 0 0 0 0 1079241 0 +AAADYFGMPLYR MGYG000001420_02263;MGYG000002203_01744;MGYG000002082_02009;MGYG000000003_00610;MGYG000000074_00749 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,22U9M@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000001420_02263 0.2 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 2880556 2992618 2014045 3616447 2010927 2626508 2884742 0 3311450 3603179 919661 4179778 2571608 2504857 3224531 2061663 3370466 0 4342551 3021406 3191736 2110833 0 2984581 2928422 3017993 3741592 0 2759441 6166898 2296809 3020433 1839945 0 2372382 3408139 3527803 1199050 2595907 1956710 3360092 3856683 2893340 2597902 2089675 2899661 2146126 3736778 2823836 3518908 2387543 3371879 4546781 2951667 2778648 0 4831515 4599774 4240981 3305623 0 2394560 3280413 3481422 2937355 0 2817353 3568630 1873912 3673301 2543626 2255065 2376242 2417321 2752697 2611181 1714017 999272 613077 779138 1398936 375421 458613 620362 2392770 645888 705453 940809 760930 445292 519985 0 1233320 0 638031 672177 2593311 535541 0 515911 383636 427014 400485 0 1099503 564760 469197 369585 611034 784783 281373 1900724 691111 330936 1847701 1315826 1644932 1410806 1775930 1907116 2623167 1879947 1743698 1968593 988989 2289117 1700025 2343690 2289056 1734937 1325954 0 2284524 1808513 2321093 906222 0 917636 2831717 2417229 1931190 0 1414645 1932444 1183771 1567031 1928884 1365496 1687843 2019917 2778110 979553 4210874 4593542 1259641 10310748 10734566 3075145 1369697 3388868 3422601 1122796 1592052 2514391 12703900 867458 124061 5197986 1732487 0 10247431 15604284 1403246 6399584 0 7422721 3573667 9484733 4624958 0 8187441 12069569 3808809 7874989 1548495 0 6129096 3545693 7263310 5083889 +AAAEAAAAQK MGYG000000003_00520;MGYG000003279_02451 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_00520 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1686008 829395 204577 1236256 0 387738 844822 354465 1421757 897820 175576 976157 394015 0 1616957 406030 772549 0 1461250 282860 1597250 307676 0 870627 1030748 1192730 1567371 0 1015455 1350857 0 0 401487 55198 915152 1331529 1202942 335402 333620 230259 411720 425584 0 405100 327939 424416 380702 0 473270 910610 272935 0 428867 268698 317328 0 602589 385805 361435 407259 0 580068 306730 264760 402182 0 400535 410264 0 0 222742 0 275026 258857 527911 308589 1084827 386123 670226 564413 0 159685 510872 720125 541395 964659 255115 203955 391067 0 657236 424512 681167 0 571076 1158283 1269891 284790 0 793198 771164 807808 759651 0 362665 530238 0 0 884237 1519987 883440 1315341 566681 596305 181352 94128 45047 395566 0 153026 909430 196977 486957 161369 95575 121457 0 0 0 241309 208761 0 370519 318396 0 187759 0 304378 77251 0 148240 0 150193 0 0 0 54061 124760 177049 134083 193254 89711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEAAEAPKAE MGYG000004487_00048;MGYG000002720_01558;MGYG000002090_00804 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG2768@1|root,COG2878@1|root,COG2768@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,2N6NY@216572|Oscillospiraceae 0.6666666666666666 186801|Clostridia 1.0 C 0.6666666666666666 Putative Fe-S cluster 0.6666666666666666 rnfB 0.6666666666666666 - 1.0 - 0.6666666666666666 ko:K03616 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 ko00000 0.6666666666666666 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_13,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004487_00048 0.3333333333333333 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 - 0.6666666666666666 K03616:rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] 0.6666666666666666 none 1.0 859406 653818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 952454 0 0 0 0 0 0 0 0 632210 0 0 0 0 0 0 0 1017215 0 0 726574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEAAEGAEE MGYG000000802_00126;MGYG000001636_01005;MGYG000002775_01401;MGYG000003122_01642;MGYG000002050_00255;MGYG000002947_00311;MGYG000003274_00534;MGYG000003266_00528;MGYG000002961_01014;MGYG000004681_00342 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CWB2@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 - 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000802_00126 0.1 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 773311 0 1142395 0 0 1011557 0 0 0 0 0 0 0 0 0 0 0 0 327520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 595366 0 279934 0 0 153321 0 0 0 0 0 0 0 0 0 0 0 0 248021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164919 0 461190 0 0 799664 0 0 0 0 0 0 0 0 0 0 0 0 352595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2179666 0 1911632 0 0 3009442 0 0 0 0 0 0 0 0 0 0 0 0 1285178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 129122 0 591850 0 0 407976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEADIAQER MGYG000004866_01541;MGYG000001627_00734;MGYG000003937_00315;MGYG000000724_00927;MGYG000001157_02268;MGYG000000573_01525;MGYG000000084_01366;MGYG000003921_00616 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,3WIRW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) 1.0 atpF 1.0 - 1.0 - 1.0 ko:K02109 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 iHN637.CLJU_RS01170 1.0 ATP-synt_B,DUF2130 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004866_01541 0.125 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02109:ATPF0B, atpF; F-type H+-transporting ATPase subunit b 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 893598 0 0 0 0 808506 0 0 0 0 1213848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386239 0 0 0 0 505516 0 0 0 0 460792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276588 0 0 0 0 443165 0 0 0 0 386601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 969911 0 0 0 0 1052342 0 0 0 0 1117825 0 0 0 0 0 0 0 0 0 0 +AAAEAIKPMC(Carbamidomethyl)ELQYELAK MGYG000003697_00700 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003697_00700 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 208588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 978631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEAIKPMC(Carbamidomethyl)ELQYELAKEK MGYG000003697_00700 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003697_00700 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 811916 0 0 180256 0 0 0 0 0 0 0 0 0 507546 0 0 0 0 0 82617 0 327467 0 0 0 0 0 0 0 0 687215 151655 0 0 0 76844 0 0 0 0 0 319093 0 0 0 0 0 0 0 0 0 85625 0 0 0 0 0 0 0 323265 0 0 0 0 0 0 0 0 0 0 0 0 0 375480 0 0 698246 0 0 969439 0 0 0 0 0 0 0 0 0 226443 0 0 0 0 0 980037 0 1115248 0 0 0 0 0 0 0 0 0 897118 0 0 0 928803 0 0 874556 0 0 781388 0 0 0 0 0 0 0 0 0 707272 0 0 0 0 0 930167 0 440540 0 0 0 0 0 0 0 0 589544 918046 0 0 0 551712 0 0 0 0 0 1571598 0 0 0 0 0 0 0 0 0 627696 0 0 0 0 0 899125 0 1424254 0 0 0 0 0 0 0 0 767601 768260 0 0 0 0 +AAAEAK(Lys->Glu)AAEAPK MGYG000004276_00796 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4|s__ER4 sp900550165|m__MGYG000004276 1.0 COG2768@1|root,COG2878@1|root,COG2768@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,2N6NY@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Putative Fe-S cluster 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_13,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004276_00796 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03616:rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 558734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEALAAK MGYG000003921_00586 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,3WH8C@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 T 1.0 domain protein 1.0 yybT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DHH,DHHA1,GGDEF,PAS_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_00586 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1028288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEALGMPLYK MGYG000004893_01711;MGYG000000953_00361;MGYG000002485_02554 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0148@1|root,COG0148@2|Bacteria,378QW@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 H 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000004893_01711 0.3333333333333333 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 114883 0 97673 57956 48191 144727 31862 370397 52830 76601 74944 0 61130 0 119500 55550 0 0 74165 0 0 141188 0 0 0 79079 0 0 0 65375 0 0 162855 89364 0 200070 60218 0 0 0 9012607 3173544 8463058 13466596 8470789 6887209 5028220 13774861 10936910 6594848 11350908 0 7271673 13223122 0 0 6278550 0 7407027 13634234 0 0 0 8935479 7965081 0 0 7723113 0 0 11278835 5906288 7960447 7355184 7494476 0 0 0 61524 47309 58540 60103 530277 0 59659 0 49914 88033 293075 0 67378 0 0 0 252621 0 60084 70541 0 202047 0 0 57028 0 0 51840 0 0 69745 0 0 0 0 67238 140639 0 150485 172781 63070 82799 76490 74160 62503 0 0 146124 0 0 76182 0 0 0 52474 0 945588 86378 0 259908 0 98873 211131 0 0 76255 0 0 150420 75494 61930 62306 0 140861 144715 0 0 77035 0 0 237804 55594 163735 146639 0 246117 0 0 191003 27577 0 0 129586 0 0 0 0 0 0 100480 128415 0 0 0 0 0 0 56848 0 0 0 0 +AAAEALGTSLYNYIGGANAK MGYG000000099_02352 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,268GV@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000000099_02352 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 0 0 0 0 479534 111334 0 0 0 0 0 0 0 0 0 0 0 89232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1039995 0 0 1346712 0 0 1505931 978377 0 941231 0 0 0 1159028 1247593 0 932148 0 0 1208132 0 0 0 0 0 1030712 1197280 0 1409338 0 0 0 0 1092313 814165 1130837 725452 0 0 0 0 683255 0 0 0 234724 0 106621 0 0 0 285108 351514 0 870132 0 0 0 0 0 0 0 0 0 0 0 599521 0 0 0 0 641762 151049 0 0 0 0 0 0 0 0 0 200968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5783 0 0 0 0 0 0 0 0 0 0 917696 0 0 0 0 0 0 0 0 0 0 2318896 0 0 3117452 0 0 0 0 0 88718 0 94638 0 +AAAEAPAEEAAAAPAEEAPATEAAAE MGYG000001378_01465;MGYG000001345_02599 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_01465 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 598635 0 0 0 0 424135 1075325 0 0 1008345 2527839 0 0 0 0 0 0 0 0 0 861671 723105 0 1017039 0 776951 867582 0 0 0 0 0 0 0 0 946299 807632 0 245730 0 0 0 0 229532 124684 0 0 247293 1194881 0 0 0 0 0 0 0 0 0 108763 304976 0 335782 0 415106 161256 0 0 0 0 0 0 0 0 131017 358933 0 0 0 0 0 0 219486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525025 0 267999 0 0 0 0 0 0 0 0 0 271034 0 0 425987 0 0 0 0 486902 512241 0 0 218154 1159409 0 0 0 0 0 0 0 0 0 803992 0 0 385367 0 276429 391351 0 0 0 0 0 0 0 0 422449 389029 0 0 0 0 0 0 737021 281100 0 0 333079 123281 0 0 0 0 0 0 0 0 0 0 198369 0 908704 0 140711 0 0 0 0 0 0 0 0 0 270677 215183 0 +AAAEAPAEEAPAEEAPAAEEAAAE MGYG000001346_00042 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_00042 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1304415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3463504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEAPAEEATEAAAEEAPATEAAAE MGYG000002561_03440 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp902388495|m__MGYG000002561 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002561_03440 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEAPAEEATEAPAEEAAATEAAAE MGYG000000196_03725 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_03725 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 1149947 0 0 1170133 0 1001350 894974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1022278 0 0 0 1083596 0 0 740564 0 0 0 0 0 0 0 0 0 0 337736 0 534084 726664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271815 0 0 0 436967 0 0 385508 0 0 0 0 0 0 0 0 0 0 439442 0 176197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189999 0 0 261757 0 0 0 0 0 0 0 0 0 0 207587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260218 0 0 243884 0 0 0 0 0 0 0 496354 0 0 160776 0 200385 277774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366735 0 0 0 215908 0 0 510646 0 0 0 0 +AAAEAPAEEATEAPAEEAPAAEAAAE MGYG000002455_05203 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_05203 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1023408 0 0 0 0 751520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEAPAEETAAPAEEAPATEAAAE MGYG000002549_01142 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_01142 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1238453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 202605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1365303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEAYFGK MGYG000000196_01844;MGYG000000029_02657;MGYG000003312_02145;MGYG000001345_04496 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_01844 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 3954518 3961676 2324731 4537009 1979347 2905371 4879439 3156055 3697030 3238535 1769904 2947706 1987293 2465771 3039415 2375072 3861903 1180260 2422244 3727546 3942283 1865545 1799105 4061411 3021561 3550310 3789243 0 4912967 3892245 2785494 3848743 2898626 4419537 4801713 4916346 3285577 2596846 3163828 2098386 3219711 3508390 2865862 0 2301861 0 2955972 3182740 3351876 0 2799437 3352210 0 0 2650855 1328287 2624819 2469130 2856382 3907625 1789599 2664303 3112427 0 2543256 1420020 2920719 2771141 2009424 2620327 2443549 2876818 0 2816028 2955962 0 2008721 644779 1588591 1906851 2608211 2209051 2783542 1827651 2415679 1273293 1553952 1234892 1179920 1786716 1846324 1239330 1612443 2636244 1373518 1586878 2065635 1263719 1896808 2621888 1752535 1936752 1611486 818896 1605079 1141266 1698135 1330942 1167874 1546418 1237894 2428417 0 1478959 1032956 1005216 1207197 1201005 993644 964722 1328316 940725 945314 1142607 1478428 1282318 1516712 861619 748985 887238 1209566 1104317 623387 819565 1096251 724694 1472589 609689 1278446 1337484 880707 740764 557287 1097776 893992 1179115 1029409 1123164 1184085 1390570 1041558 775246 2642867 1627891 0 2323010 2036558 3439590 2769274 2868851 2949110 1846696 1336555 1933805 1996540 1623418 1922730 2159375 2141558 1686295 1537736 2806146 2354687 3614838 1674595 3664830 2672422 3283423 2090406 1426841 1647304 3182863 1863645 2248412 1185087 3136323 2491381 2088320 2729601 1690327 +AAAEEAGASGDSAPK MGYG000004158_01106;MGYG000004158_01109;MGYG000001683_02241 domain d__Bacteria 1.0 COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,4H3G4@909932|Negativicutes 1.0 909932|Negativicutes 1.0 P 1.0 Transporter DASS family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CitMHS,Na_sulph_symp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004158_01106 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 1098727 0 963242 1399777 0 0 0 0 0 1760935 0 0 0 0 1124802 0 0 0 1039666 0 0 0 0 1058578 0 0 0 1635137 0 1776682 1390904 0 1280737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEEAGITPETSASDTC(Carbamidomethyl)DKMK MGYG000000233_00306 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,21XVQ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Receptor family ligand binding region 1.0 braC 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_00306 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 1.0 K01999:livK; branched-chain amino acid transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 782663 0 0 1096031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEEHHVEYEER MGYG000000028_00251 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus_A|m__MGYG000000028 1.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family 1.0 lysS 1.0 - 1.0 6.1.1.6 1.0 ko:K04567 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03658 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DUF2156,tRNA-synt_2,tRNA-synt_2_TM,tRNA_anti-codon,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000028_00251 1.0 lysine--tRNA ligase. lysyl-tRNA synthetase. - ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K04567:KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 785661 0 151045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEELGLK MGYG000002960_00316;MGYG000002293_01627 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,2FPIS@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Carbohydrate kinase, FGGY family protein 1.0 xylB_2 1.0 - 1.0 2.7.1.17 1.0 ko:K00854 1.0 ko00040,ko01100,map00040,map01100 1.0 M00014 1.0 R01639 1.0 RC00002,RC00538 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002960_00316 0.5 xylulokinase. Xylulose kinase. - ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+). 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Metabolic pathways 1.0 K00854:xylB, XYLB; xylulokinase [EC:2.7.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7317666 0 0 0 0 4303703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEEVLGKDER MGYG000001346_02345 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0312@1|root,COG0312@2|Bacteria,4NE1F@976|Bacteroidetes,2FPXY@200643|Bacteroidia,4AMRA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Psort location Cytoplasmic, score 9.26 1.0 tldD3 1.0 - 1.0 - 1.0 ko:K03592 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01002 1.0 - 1.0 - 1.0 - 1.0 PmbA_TldD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_02345 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03592:pmbA; PmbA protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 323837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEFTDVK MGYG000002720_00025;MGYG000004475_00733 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,2N6G4@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate-binding protein PnrA-like 1.0 tmpC 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_00025 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07335:bmpA, bmpB, tmpC; basic membrane protein A and related proteins 1.0 none 1.0 7850631 0 7747171 7463496 0 8415019 9263167 8119035 0 0 0 0 0 0 7288557 0 8206658 0 0 0 0 7375610 0 7939648 7872468 7788271 0 0 10671868 0 6398930 6821235 6843128 0 7760422 0 8366962 7156853 0 0 208628 334285 0 337124 583249 412177 0 0 0 0 0 0 263866 0 330088 0 0 0 0 253522 0 447590 464326 482589 0 0 601020 0 0 101497 178173 0 205540 0 256523 461290 1138777 0 814416 612433 0 839775 576465 1231364 0 0 0 0 0 0 389895 0 581124 0 0 0 0 475825 0 722666 703139 560182 0 0 614153 0 745077 818521 323071 0 174176 0 651445 568808 813090 0 2033564 982436 0 950086 1512362 1226020 0 0 0 0 0 0 988179 0 1455992 0 0 0 0 2380097 0 2025231 974392 844501 0 0 1494371 0 1414053 420400 1558970 0 1042970 0 732704 2186523 653125 0 0 125002 0 0 125309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164345 0 0 0 0 0 200594 335075 140756 0 0 0 0 115406 +AAAEGAGAAEKDEFDVELTSAGASK MGYG000000249_00044 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_00044 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 921219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEGAIGIAEK MGYG000000118_02684;MGYG000000142_02731;MGYG000000038_01050;MGYG000004604_01207;MGYG000001338_01296;MGYG000000179_04738;MGYG000000127_05084;MGYG000002528_00119;MGYG000000515_00648;MGYG000000205_02543;MGYG000000217_02528;MGYG000002985_01044;MGYG000000262_01832;MGYG000004762_01356;MGYG000002517_01686;MGYG000000187_00466;MGYG000000212_00326;MGYG000002492_01963;MGYG000000198_05683;MGYG000000245_00061;MGYG000000280_02029;MGYG000000251_02115;MGYG000000312_02568;MGYG000001615_01983;MGYG000000233_02118;MGYG000001496_01287;MGYG000000249_02372;MGYG000001707_00757;MGYG000002880_00963;MGYG000003425_04615;MGYG000004733_02764;MGYG000000301_00647 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.375 186801|Clostridia 0.90625 S 0.90625 Psort location Cytoplasmic, score 8.87 0.46875 - 0.90625 - 1.0 - 0.90625 - 0.90625 - 0.90625 - 0.90625 - 0.90625 - 0.90625 - 0.90625 - 1.0 - 1.0 - 1.0 GGGtGRT 0.90625 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000118_02684 0.03125 - - - - 0.90625 0.90625 0.90625 0.90625 - 0.90625 - 0.90625 none 1.0 1353283 1319401 293497 336510 0 0 0 0 0 677756 0 0 0 0 0 0 0 0 480979 589634 0 0 0 0 616051 0 0 457556 989322 0 349113 0 996222 0 0 582881 0 328173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733947 0 0 0 0 279440 0 0 0 0 1041098 0 0 0 0 0 0 0 0 0 163806 1842006 1359610 2129733 1506395 0 0 1073621 0 0 1780562 0 0 0 1345052 0 1201707 924491 644355 1751896 1758464 0 0 869007 0 1690634 1590410 1472810 823679 1533508 0 574717 1196358 1738905 1944562 0 1392878 1894479 1733136 564584 948226 0 756790 0 0 0 0 0 604488 0 0 0 730160 0 609209 1002843 668523 391503 904978 0 0 344585 0 311406 0 755523 1584174 1226275 0 1046080 365416 566092 0 0 444831 370296 1010447 464782 335254 930728 1438745 0 0 1758943 0 0 1603275 0 0 0 1235243 0 257826 0 552664 1280651 496060 0 0 909443 0 953877 956465 1412484 830785 1702111 0 788173 450428 1238903 391432 0 617843 1019116 804706 +AAAEGAIGIAR MGYG000001627_00963;MGYG000001300_02120;MGYG000002274_00309;MGYG000000258_00155;MGYG000003937_01695;MGYG000000223_01510;MGYG000004732_00759 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae 0.8571428571428571 186801|Clostridia 0.8571428571428571 S 1.0 Psort location Cytoplasmic, score 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001627_00963 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 408935 657154 0 0 0 0 0 0 0 1469548 0 0 454506 0 0 0 0 0 0 1102504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432362 0 0 0 0 687091 0 0 0 0 594983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1344608 1296666 0 0 0 0 0 0 0 2044391 0 0 0 0 1583236 0 0 0 952885 0 0 1594459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2349389 0 0 973904 0 2164089 0 0 0 1426979 3361848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEGDGDMINGR MGYG000002293_01819;MGYG000001338_00685;MGYG000003697_01754 domain d__Bacteria 1.0 COG2407@1|root,COG2407@2|Bacteria,4NFGS@976|Bacteroidetes,2FMDZ@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 0.6666666666666666 G 1.0 L-fucose isomerase, C-terminal domain 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01819 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 129438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1039846 0 0 711613 567534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769318 0 944248 0 0 0 0 0 0 0 0 435381 0 0 0 0 730098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEGELK MGYG000001712_05136 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Bacillales|f__Bacillaceae_G|g__Bacillus_A|s__Bacillus_A thuringiensis_S|m__MGYG000001712 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus 1.0 91061|Bacilli 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gapA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001712_05136 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1045065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1250183 0 901588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEGEMK MGYG000002506_01169 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gapA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_01169 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 1210873 0 0 0 935332 1100234 0 1001052 0 0 193734 0 614600 1144256 0 0 540797 0 0 0 1104918 1169438 0 3210204 0 1014549 0 0 728875 0 0 525009 0 966125 915947 0 772984 0 357966 0 0 0 726065 1839359 0 833920 0 0 629846 0 732061 471714 0 0 626508 0 0 0 484061 1448956 0 2074133 0 266681 0 0 545482 0 0 361497 0 63820 446921 0 522296 0 1249172 0 0 0 489602 1598414 0 767746 0 0 662672 0 661518 621511 0 0 1325917 0 0 0 886422 1241476 0 11875454 0 1631137 0 0 290369 0 0 433009 0 1248912 1657751 0 488842 0 212250 0 0 0 199518 1309500 0 755035 0 0 712264 0 2481695 494862 0 0 202294 0 0 0 2157621 2265370 0 1587791 0 695402 0 0 571634 0 0 700280 0 442206 601747 0 542697 0 120950 0 0 0 0 0 0 0 0 0 0 0 0 150603 0 0 0 0 0 0 0 0 0 156588 0 95244 0 0 100497 0 0 0 0 0 239162 0 0 0 +AAAEGIAYVK MGYG000002528_01658 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,24819@186801|Clostridia,21ZS7@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 1.0 carB2 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01658 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01955:carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] 1.0 none 1.0 0 0 0 0 0 216545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1045001 0 388175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEIAGLNNATGC(Carbamidomethyl)DVR MGYG000003895_00007 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Negativibacillus|s__|m__MGYG000003895 1.0 COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,2499C@186801|Clostridia,21YIA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 I 1.0 Psort location Cytoplasmic, score 8.87 1.0 grdC 1.0 - 1.0 1.21.4.2,1.21.4.3,1.21.4.4 1.0 ko:K21577 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ACP_syn_III,FA_synthesis 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003895_00007 1.0 glycine reductase. | sarcosine reductase. | betaine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. | The reaction is observed only in the direction of sarcosine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.4. | The reaction is observed only in the direction of betaine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.3. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. | [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine. | [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate. 1.0 1.0 1.0 1.0 - 1.0 K21577:grdC; glycine/sarcosine/betaine reductase complex component C subunit beta [EC:1.21.4.2 1.21.4.3 1.21.4.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 967094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEIEEFR MGYG000000074_02203 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,2FNZN@200643|Bacteroidia,22U4G@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily 1.0 pheS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.20 1.0 ko:K01889 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Phe_tRNA-synt_N,tRNA-synt_2d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02203 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01889:FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] 1.0 none 1.0 342256 0 332078 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199764 0 0 0 492891 0 0 0 0 0 0 339153 269985 794937 0 659887 0 0 0 0 438344 0 0 0 0 0 0 0 385949 0 0 834715 525155 0 0 0 0 0 543644 0 0 0 285572 0 0 503078 0 0 0 466297 431856 0 0 559374 0 0 0 0 631883 0 0 0 0 0 0 0 326443 0 0 0 476733 0 0 0 0 0 0 0 0 426324 838285 0 0 587253 0 0 0 353138 454557 424407 0 210063 0 0 0 0 426039 0 0 0 0 0 0 0 367889 0 0 0 809450 0 0 0 0 0 609495 0 0 415697 259909 0 0 0 0 0 0 385078 0 856924 0 449903 0 0 0 0 743548 0 0 0 0 0 0 0 929583 0 0 1343032 1669937 0 0 0 0 0 824995 0 0 627498 1214443 0 0 326642 0 0 0 1016761 920007 +AAAEIILK MGYG000000118_02724;MGYG000000133_02501 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C6IR@1|root,33WXF@2|Bacteria,1VVM0@1239|Firmicutes,24QSU@186801|Clostridia 0.5 186801|Clostridia 1.0 - 0.5 - 0.5 - 1.0 - 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000118_02724 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEKAEITPDMSTSEIC(Carbamidomethyl)DALK MGYG000000164_00677 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,3WI31@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 ABC-type branched-chain amino acid transport systems periplasmic component 1.0 braC 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_00677 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 1.0 K01999:livK; branched-chain amino acid transport system substrate-binding protein 1.0 none 1.0 1922650 0 0 0 1583969 1828018 1878285 3338370 2472681 2782193 0 0 2139680 1529534 2038441 1464392 1598155 0 1768412 2027851 2132483 2119823 0 1356216 2267711 2788653 2770760 0 0 1270179 0 0 0 3248976 0 0 2208595 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAELDGPVYMR MGYG000000080_00459 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Transketolase 1.0 tktB 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_00459 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5840933 0 0 0 0 0 0 0 0 0 +AAAELGYPVIIR MGYG000002293_01440 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 EF 1.0 Carbamoyl-phosphate synthase (glutamine-hydrolyzing) 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01440 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01955:carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1026159 0 0 0 0 1593502 0 0 0 0 850956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAELVQALK MGYG000000179_00905;MGYG000000198_02625 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,21YF6@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_00905 0.5 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 1.0 none 1.0 755729 0 0 0 0 0 654759 0 569192 3677255 0 0 0 802494 919173 0 0 0 0 664756 0 0 0 0 0 2973783 139419 0 677771 489946 0 0 0 599035 0 719242 2925299 0 1026528 0 0 0 0 0 170338 0 306593 284543 0 0 0 108072 385021 0 0 0 0 380845 0 0 0 0 0 372015 345924 0 1268509 142538 0 0 0 179634 0 1361947 272180 0 2908453 0 0 0 0 0 3240502 0 1037178 3864546 0 0 0 1012063 923673 0 0 0 0 3433104 0 0 0 0 0 721151 961680 0 1164791 4656412 0 0 0 3666199 0 3406790 696036 0 627562 0 0 0 0 0 2703870 0 3710333 0 0 0 0 4344966 4605026 0 0 0 0 0 0 0 0 0 0 569139 762129 0 745574 4082023 0 0 0 585123 0 715755 564121 0 1069050 0 0 0 0 0 787472 0 2711595 699576 0 0 0 897225 994518 0 0 0 0 1416306 0 0 0 0 0 799129 1053180 0 923955 982708 0 0 0 1250829 0 842912 662658 0 +AAAENIIPHTTGAAK MGYG000002506_00654;MGYG000002494_01095;MGYG000002515_01523;MGYG000002534_02628;MGYG000002477_03045 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,3XQM0@561|Escherichia 0.6 1236|Gammaproteobacteria 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.6 gapC 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iJR904.b1416,iJR904.b1417 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00654 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 379906 808312 0 0 0 224356 0 0 0 480634 0 0 0 0 0 0 0 0 182916 0 0 119187 0 238780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 720127 1945041 1559459 0 0 3058883 0 0 0 805746 0 0 0 0 0 645323 1260716 0 1183847 0 0 3041346 0 2740798 784535 480611 0 0 2095126 0 0 0 1586799 0 0 637802 529284 1438200 0 164118 452385 0 0 0 0 0 0 0 0 0 0 0 0 0 300242 0 276204 0 0 388786 0 300145 0 0 0 0 0 0 0 0 236095 0 0 0 267570 358643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99080 556286 450620 0 0 589156 0 0 0 444573 0 0 0 0 0 716509 522133 0 288717 0 0 668679 0 587728 460009 716831 0 0 483980 0 0 0 0 0 0 0 83700 0 +AAAENMIPTSTGAAK MGYG000001712_05136 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Bacillales|f__Bacillaceae_G|g__Bacillus_A|s__Bacillus_A thuringiensis_S|m__MGYG000001712 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1ZCF9@1386|Bacillus 1.0 91061|Bacilli 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gapA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001712_05136 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 240317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907188 0 496300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEPAPVNPC(Carbamidomethyl)IR MGYG000002272_02058 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_D|m__MGYG000002272 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4,Fer4_10,Fer4_4,Fer4_7,Fer4_8,Fer4_9,MTHFR_C,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002272_02058 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03615:rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 643031 0 0 0 0 661950 0 0 0 0 688463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293811 0 0 0 0 0 0 0 0 0 598469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 500944 0 0 0 0 614372 0 0 0 0 648142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 835756 0 0 0 0 667393 0 0 0 0 1166904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEQDYEEFGKK MGYG000000243_00376 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,4AK9W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrA 1.0 - 1.0 1.6.5.8 1.0 ko:K00346 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQRA,NQRA_SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00376 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 - 1.0 K00346:nqrA; Na+-transporting NADH:ubiquinone oxidoreductase subunit A [EC:7.2.1.1] 1.0 none 1.0 0 0 1605878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 917046 0 1315366 0 0 0 0 1414751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEQELTR MGYG000001300_02745 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 P 1.0 Belongs to the TelA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TelA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02745 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 878235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 795650 0 0 0 0 0 519205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEQELTRIEDELK MGYG000001300_02745;MGYG000002223_00590 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 P 1.0 Belongs to the TelA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TelA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02745 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 349142 0 0 0 230442 0 0 0 0 204137 156886 0 0 501075 53785 0 604709 132327 0 0 0 0 181223 192314 0 0 0 290889 80604 0 212464 108888 0 0 208393 114078 393593 0 320480 0 352213 0 601063 0 0 0 0 435131 467138 0 0 340607 537950 0 703598 503470 0 0 0 0 654407 723472 0 0 0 294403 392718 0 431262 353973 0 0 415439 345026 180296 0 491970 0 556434 0 560436 0 0 0 0 268821 210337 0 0 383592 148364 0 409166 238420 0 0 0 0 211493 72185 0 0 0 209189 318450 0 144768 158071 0 0 156447 143717 361738 0 463300 0 509611 0 246453 0 0 0 0 468574 496771 0 0 474152 219792 0 462898 328712 0 0 0 0 200543 432806 0 0 0 432694 498919 0 699694 474070 0 0 362546 542461 109894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316222 47466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAESFADFAK MGYG000002279_02340 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena_B|m__MGYG000002279 1.0 COG1653@1|root,COG1653@2|Bacteria,1TPBF@1239|Firmicutes,24920@186801|Clostridia,27UWQ@189330|Dorea 1.0 186801|Clostridia 1.0 G 1.0 COG COG1653 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_02340 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAESSIQVK MGYG000002477_00984;MGYG000002494_02482;MGYG000002500_00413;MGYG000002507_00338;MGYG000002506_03694;MGYG000002534_04617;MGYG000002476_04022;MGYG000002535_04027;MGYG000002515_03649 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0085@1|root,COG0222@1|root,KOG0214@2759|Eukaryota,KOG1715@2759|Eukaryota,39VWS@33154|Opisthokonta,3BM6Z@33208|Metazoa,3DDNE@33213|Bilateria 1.0 33208|Metazoa 1.0 K 1.0 DNA-directed 5'-3' RNA polymerase activity 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5,RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7,Ribosomal_L10,Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000002477_00984 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 593106 573026 450901 131447 209194 1006712 941615 918145 604044 852311 0 543815 0 723950 411779 229891 157286 0 358692 320009 429541 1422526 0 1477902 504158 506666 353979 0 389519 536299 604876 640270 513932 752009 487272 248082 0 497685 3394296 3633691 3657801 2648138 2668782 5278678 2975432 2783765 3860489 3927483 0 2410145 0 2946491 2633772 1949391 3766746 0 3761749 2238469 4283122 6168366 0 4356663 3136178 2716305 2528639 0 4766958 4247465 1575272 2461919 4194334 2786619 2532971 2371080 2677098 2849692 952478 1167296 1179615 985534 1217163 2336601 1558371 929899 174976 1386584 0 538438 0 1517043 978234 982332 1029455 0 867910 788161 1224008 1924233 0 2069402 811327 1076926 991320 0 1010462 1272072 1473771 740320 1208591 1310051 1055671 0 1158923 591302 218591 0 0 268584 755483 837492 2200390 730941 0 429737 0 0 0 687074 1446171 175760 1441782 0 0 1063365 1510818 1439997 0 0 301461 0 0 0 213300 220692 0 0 0 2019930 1887759 1769259 901545 741981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285433 0 0 0 +AAAESYLGK MGYG000001661_01238;MGYG000001337_04131;MGYG000000243_03128;MGYG000001313_00261;MGYG000000236_03748;MGYG000000224_00588 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001661_01238 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 312702 0 0 0 0 344660 0 0 0 0 0 0 0 0 0 0 0 310765 0 0 138222 230367 0 225472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192943 0 0 0 0 0 130512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3293055 0 0 0 0 3289070 4557739 0 0 0 0 0 0 0 0 0 0 18183206 0 0 3155456 2542865 14550410 791479 0 2344002 0 12682528 0 0 0 0 0 0 0 0 2877768 0 784153 0 0 0 0 1312662 1091733 0 0 0 0 0 0 0 0 0 0 2943821 0 0 284944 1370474 1320577 1547659 0 859685 0 1851794 0 0 0 0 0 0 0 0 470706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 922532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAETYFGK MGYG000002549_03156 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_03156 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 92682 0 0 0 136220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196480 0 0 0 0 0 0 0 0 0 0 0 0 0 1320579 0 0 0 3377779 0 0 0 2173885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 774066 0 0 0 1710109 0 0 0 0 0 0 0 0 0 610318 0 0 0 1378697 0 0 0 502839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 620985 0 0 0 327356 0 0 0 0 0 0 0 0 0 516313 0 0 0 683545 0 0 0 661980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511717 0 0 0 724279 0 0 0 0 0 0 0 0 0 1066958 0 0 0 2094794 0 0 0 914263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055276 0 0 0 1309084 0 0 0 +AAAETYGIK MGYG000000445_01242 genome d__Bacteria|p__Proteobacteria|c__Alphaproteobacteria|o__RF32|f__CAG-239|g__RUG410|s__|m__MGYG000000445 1.0 COG0673@1|root,COG0673@2|Bacteria,1MV7C@1224|Proteobacteria,2TQM1@28211|Alphaproteobacteria,2JUHP@204441|Rhodospirillales 1.0 204441|Rhodospirillales 1.0 GM 1.0 Oxidoreductase family, NAD-binding Rossmann fold 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GFO_IDH_MocA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000445_01242 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 933678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAETYL(Xle->Phe)GK MGYG000003681_02191;MGYG000004763_02569;MGYG000004797_03123;MGYG000002478_01519 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_02191 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1294522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1438717 0 0 0 0 0 0 0 0 +AAAETYLGK MGYG000003681_02191;MGYG000004763_02569;MGYG000004797_03123;MGYG000002478_01519 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_02191 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 281497 611568 342825 653181 0 419012 505095 362176 495582 691456 299852 289076 0 285727 294347 364472 770369 596194 483326 0 416771 489405 360414 580058 0 573344 546485 321114 172771 518982 227432 685508 577118 0 658330 503338 544413 372458 4074378 1950228 3143243 4704635 0 2477579 3427650 4447976 4862117 4402100 2025344 4592110 0 4659902 3609173 2252263 3088394 2714717 3707664 4272453 3478299 2763107 4122837 2610476 0 4154355 3989189 3760805 3105810 4398860 2039575 2448023 3097965 0 5115604 2267278 5152768 4378134 1034585 442745 916717 725146 0 868375 1366429 696875 1335297 775116 925394 558086 0 1280196 1208287 418418 994688 4739840 990725 829333 939181 524443 3545422 1182345 0 975048 942695 3443481 988600 881378 849024 705911 405463 0 687659 1244367 1044905 768252 319627 910648 743995 273653 0 857898 1020957 0 429064 531019 1163614 820583 0 0 505621 1146553 0 2559887 1034205 0 0 1049307 1699597 610555 0 918841 248117 1345404 853626 393964 814031 862963 645656 0 411087 994301 570730 739683 119675 0 0 224599 0 0 0 0 0 0 0 0 0 0 0 0 0 1885771 0 0 0 0 1218952 0 0 0 0 806900 0 0 0 107336 404894 0 266708 0 561241 0 +AAAETYLSK MGYG000002455_01371 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_01371 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEVAGLLNATGSDSR MGYG000001315_00855 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,2499C@186801|Clostridia,27JWX@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 I 1.0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 1.0 grdC 1.0 - 1.0 1.21.4.2,1.21.4.3,1.21.4.4 1.0 ko:K21577 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ACP_syn_III,FA_synthesis 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_00855 1.0 glycine reductase. | sarcosine reductase. | betaine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. | The reaction is observed only in the direction of sarcosine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.4. | The reaction is observed only in the direction of betaine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.3. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. | [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine. | [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate. 1.0 1.0 1.0 1.0 - 1.0 K21577:grdC; glycine/sarcosine/betaine reductase complex component C subunit beta [EC:1.21.4.2 1.21.4.3 1.21.4.4] 1.0 none 1.0 681382 788498 1189194 536787 1245255 746712 385707 548375 636131 935656 1447062 935133 885598 613966 834148 891334 702814 430797 824057 664228 0 722658 338068 513973 593004 496870 509514 197755 502289 428923 58669 664317 879938 529328 538151 690790 297327 934870 2555302 2300597 1264319 2682995 1517429 1473126 2649665 2720792 1674828 1411283 1201293 1506788 1777402 1713479 1664436 1022281 1499818 1637220 2315446 2574512 0 808144 299943 2335080 2345688 2347449 2722844 1151422 3088183 1671778 3012073 1842531 1439911 2689570 2106388 3007057 2042739 1312159 897378 821415 937578 789004 581621 116802 646921 957022 935038 751616 728866 821354 915112 742884 972361 786433 1014158 880776 645311 881085 0 1078695 806787 636540 882015 891712 1015813 1233067 255164 845351 626377 0 846728 1198426 903918 603685 711622 535644 894260 1051763 974641 529692 947405 718868 717402 658881 498072 690612 695534 945699 1123941 737848 812218 1256474 823312 574647 808947 1082763 0 1110543 153927 804022 779334 713581 888272 549971 0 902823 868504 1220320 987062 494045 710997 610912 589139 998732 0 890467 1635478 2570603 631394 1070255 2273519 1866181 1356371 1930034 1763556 1428595 937540 2650166 1449723 1450169 1510183 539731 1184604 941101 0 1647875 252788 1315449 2047773 1276745 1832111 610105 2350498 582221 1835891 0 528311 0 2057875 2409237 1308889 1586661 +AAAEVAGLVSA(Ala->Gly)TGSDAR MGYG000001496_02720 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Extibacter|s__Extibacter sp001185345|m__MGYG000001496 1.0 COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,2499C@186801|Clostridia,21YIA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 I 1.0 Psort location Cytoplasmic, score 8.87 1.0 grdC 1.0 - 1.0 1.21.4.2,1.21.4.3,1.21.4.4 1.0 ko:K21577 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ACP_syn_III,FA_synthesis 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001496_02720 1.0 glycine reductase. | sarcosine reductase. | betaine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. | The reaction is observed only in the direction of sarcosine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.4. | The reaction is observed only in the direction of betaine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.3. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. | [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine. | [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate. 1.0 1.0 1.0 1.0 - 1.0 K21577:grdC; glycine/sarcosine/betaine reductase complex component C subunit beta [EC:1.21.4.2 1.21.4.3 1.21.4.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEVAGLVSAT(Thr->Ser)GSDAR MGYG000001496_02720 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Extibacter|s__Extibacter sp001185345|m__MGYG000001496 1.0 COG0332@1|root,COG0332@2|Bacteria,1TQSB@1239|Firmicutes,2499C@186801|Clostridia,21YIA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 I 1.0 Psort location Cytoplasmic, score 8.87 1.0 grdC 1.0 - 1.0 1.21.4.2,1.21.4.3,1.21.4.4 1.0 ko:K21577 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ACP_syn_III,FA_synthesis 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001496_02720 1.0 glycine reductase. | sarcosine reductase. | betaine reductase. - The reaction is observed only in the direction of glycine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.3 and EC 1.21.4.4. | The reaction is observed only in the direction of sarcosine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.4. | The reaction is observed only in the direction of betaine reduction.-!-The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C.-!-Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for glycine binding and ammonia release.-!-Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate.-!-Only subunit B distinguishes this enzyme from EC 1.21.4.2 and EC 1.21.4.3. [thioredoxin]-disulfide + acetyl phosphate + H2O + NH4(+) = [thioredoxin]-dithiol + glycine + H(+) + phosphate. | [thioredoxin]-disulfide + acetyl phosphate + H2O + methylamine = [thioredoxin]-dithiol + H(+) + phosphate + sarcosine. | [thioredoxin]-disulfide + acetyl phosphate + H2O + trimethylamine = [thioredoxin]-dithiol + glycine betaine + H(+) + phosphate. 1.0 1.0 1.0 1.0 - 1.0 K21577:grdC; glycine/sarcosine/betaine reductase complex component C subunit beta [EC:1.21.4.2 1.21.4.3 1.21.4.4] 1.0 none 1.0 125411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 506600 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1011961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1167909 0 0 0 0 0 0 0 0 0 0 1047627 0 472218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEVALK MGYG000001338_00592 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3Y0DB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_00592 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02968:RP-S20, rpsT; small subunit ribosomal protein S20 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4253125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3826014 0 0 0 0 0 0 1266647 0 2763584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5488512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3047295 0 1403156 0 0 0 0 1672651 0 738427 764514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1502672 0 1728788 0 0 0 0 1360571 +AAAEVALKDAVSTISK MGYG000000200_02066;MGYG000001338_00592 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3Y0DB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000200_02066 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02968:RP-S20, rpsT; small subunit ribosomal protein S20 1.0 none 1.0 0 798085 181566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246349 454663 168258 0 0 0 0 153505 0 853373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1008428 212237 0 0 0 0 0 0 0 1464891 187356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284681 1132867 433658 0 0 0 0 218876 0 341207 158452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293114 450217 167770 0 0 0 0 0 0 1280689 731570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146282 1006582 853909 0 0 0 0 514951 +AAAEVATEVVDAVK MGYG000003937_00337 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG3940@1|root,COG3940@2|Bacteria,1UK7P@1239|Firmicutes,25FPI@186801|Clostridia,3WSNK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Ricin-type beta-trefoil lectin domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 RicinB_lectin_2 1.0 - 1.0 CBM13 1.0 - 1.0 - 1.0 MGYG000003937_00337 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 862845 0 0 915701 0 0 0 0 0 925936 0 1070965 0 1086321 1058090 0 1287329 0 785430 0 0 913032 0 925713 0 0 1139950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405334 0 0 203754 0 0 0 0 0 668662 0 207065 0 283906 562777 0 634363 0 150588 0 0 210603 0 278782 0 0 566769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264231 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAEYAATR MGYG000002961_01578;MGYG000001642_01246;MGYG000001709_01740;MGYG000001567_00451;MGYG000003266_01787;MGYG000002919_01660;MGYG000002947_01105;MGYG000002775_01057;MGYG000004681_01444;MGYG000001718_00699;MGYG000000188_00729 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,4CUV7@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 F 1.0 SAICAR synthetase 1.0 purC 1.0 - 1.0 6.3.2.6 1.0 ko:K01923 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04591 1.0 RC00064,RC00162 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 SAICAR_synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002961_01578 0.09090909090909091 phosphoribosylaminoimidazolesuccinocarboxamide synthase. SAICAR synthetase. Forms part of the purine biosynthesis pathway. 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate + ADP + 2 H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01923:purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] 1.0 none 1.0 0 1513157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAFEGELIPASQIDR MGYG000002535_04030;MGYG000002506_03691;MGYG000002323_03991;MGYG000000107_05463;MGYG000003365.1_02175;MGYG000003390_01039;MGYG000000235_04432;MGYG000002494_02479;MGYG000002366_04477;MGYG000002500_00410;MGYG000003360_03951;MGYG000002534_04620;MGYG000002515_03652;MGYG000000093_05651;MGYG000002502_01841;MGYG000002507_00341 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0244@1|root,COG0244@2|Bacteria,1RAN5@1224|Proteobacteria,1S286@1236|Gammaproteobacteria,3XM5M@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002535_04030 0.0625 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02864:RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10 1.0 none 1.0 2613041 2053670 2198962 3127702 1810110 3271554 3529737 2867816 3084954 3635005 1259724 2450092 957403 2365675 2109836 1156676 2723403 0 2381003 2530192 2620049 4045255 0 4542883 2488505 2342675 2958363 0 3307614 3022307 2170861 2367379 1913861 3339442 2471574 2897143 2517908 1938569 4646632 4617078 5060882 7139531 4893065 11662186 6212529 5275563 5401268 7967050 2057283 4874771 2912801 6376898 6260363 3418801 5454204 0 7388183 5067807 7255465 13684547 0 11132172 6808654 6189355 5738044 0 9108984 7747551 3671099 4349434 5694404 4755471 5121562 4954322 5070780 4274285 3389114 2171316 3630448 3179553 2958916 6571765 4319563 3850201 3398622 4570797 2673286 3064124 3196173 3313767 3417679 2384221 1812981 0 3208558 3846796 2831742 4619709 0 5162732 4043332 3551410 3807204 0 2180048 2765241 2973046 2013088 3052349 4416145 3776150 3777641 4012905 3247349 4096201 2651872 2859237 3262969 2343902 3829437 4042594 4456950 2704836 4054313 1919370 3050486 3084852 3462893 3782112 2940156 2946071 0 3375442 3314526 4179781 4004617 0 3151616 4761285 3509939 3960388 0 3118434 3342510 1541765 3054153 3496027 4682428 4851796 4201719 3076376 2383166 0 0 0 0 0 0 0 0 0 0 0 760380 0 411739 0 0 0 0 0 0 780636 0 0 0 435734 0 0 0 198269 276609 0 0 652514 0 0 0 0 0 +AAAFIGKDEEA MGYG000001306_01210 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,4AN49@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_01210 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1872657 0 0 0 0 2164460 0 0 0 0 1994383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293107 0 0 0 0 320196 0 0 0 0 216177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 601886 0 0 0 0 22629843 0 0 0 0 18502418 0 0 0 0 0 0 0 0 0 0 +AAAFIKEDEEA MGYG000000196_04090;MGYG000000236_02874;MGYG000001313_02980 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,4AN49@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04090 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2454451 1844730 0 2466465 0 0 0 0 0 0 1298951 0 0 0 0 0 0 0 0 0 0 0 0 1368913 0 0 0 0 0 0 0 0 0 0 1531588 0 0 0 1427785 1815505 0 0 0 0 0 0 0 0 1211920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1360806 0 0 0 0 0 0 0 0 0 0 0 0 516464 0 153890 0 0 0 0 0 0 703629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 730023 0 0 0 1471403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1538614 0 0 1318291 0 0 0 0 0 0 0 485044 0 0 0 660402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAFLKEDEEA MGYG000002478_01738;MGYG000003312_00466;MGYG000002281_00010;MGYG000004797_01414;MGYG000001378_03198;MGYG000000196_04090;MGYG000002455_03780;MGYG000000236_02874;MGYG000001313_02980 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,4AN49@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01738 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 1577973 1524689 1491075 2061635 1363743 1574025 2915848 1188624 2988337 1866548 1605181 1206663 3120900 2075168 1328246 2703415 2559685 1852337 2797782 1553513 1667740 1172144 986846 1725723 1989815 2527045 1211597 1840372 2301790 1534038 1862195 1425509 1219867 1247279 1288117 2580620 1174284 930410 1951247 890909 1971395 1568601 1993458 0 1690616 1984184 1966598 2587971 2345135 1645366 2894046 2793021 2680479 3052833 1181077 945004 1639468 1964936 0 1801056 1244005 1238801 2154106 2198852 1388609 1104998 1902597 1907971 0 1595727 1587859 1814006 2154267 1471161 2191007 1514922 1446640 729750 681113 992872 1396238 1239516 1719037 1011067 922691 972111 1177941 879648 0 740279 1123590 988598 1111815 2473318 1082929 1044458 710494 925992 2118418 1712792 885378 654032 1117465 1864246 1322961 801815 1233610 945206 489913 1086190 640905 1692632 1014033 879755 832798 802429 1010601 692983 1037380 1137978 881084 622662 713667 867652 1291009 857472 1526984 692720 729599 1669403 477188 1470158 646320 737452 888064 1302764 2406827 1168898 875572 1026139 580812 1395865 1096235 1262964 1169476 995836 1349172 524810 1121054 1085832 764841 396458 1440894 640706 1509172 2005152 3082691 1797541 2535125 1976195 2293564 1633590 3162186 1798492 2932075 1238435 1797041 1783653 2191941 4850372 2593618 1878196 2027286 1533027 3793793 1446464 1927136 1683496 1438463 3441423 1465545 3123700 1636372 1953714 434048 2346349 1976510 1724909 914003 2028615 +AAAFMKDEEEA MGYG000000243_02464 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,4AN49@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02464 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 1212480 1981353 0 1244317 0 0 2707236 0 1276223 1401155 1478053 0 0 1880047 0 0 868519 0 0 0 0 1345858 0 0 0 0 1099773 0 0 0 0 2709456 2645459 0 0 0 2262251 0 0 0 0 161721 0 0 273081 0 189217 0 0 0 0 201523 0 0 0 0 0 0 0 0 0 0 0 0 112491 0 0 0 0 0 0 0 0 0 0 0 331545 599859 0 833175 0 0 521580 0 379907 0 0 0 0 0 0 0 1762007 0 0 0 0 1325191 0 0 0 0 1289188 0 0 0 0 257842 0 0 0 0 384359 0 217469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 482200 0 0 0 0 0 0 347309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAFMKEEEA MGYG000001780_01720;MGYG000001346_00648 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,4AN49@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001780_01720 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1613534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 776009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3188305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1063960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4054954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAFVK MGYG000000133_01636;MGYG000000179_02852;MGYG000004087_00727;MGYG000002720_00599;MGYG000001315_02441 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3XZR6@572511|Blautia 0.2 186801|Clostridia 1.0 I 0.4 Acetyl-CoA carboxylase alpha subunit 0.2 - 0.6 - 1.0 - 0.6 - 0.6 - 0.6 - 0.6 - 0.6 - 0.6 - 0.6 - 1.0 - 1.0 - 1.0 Carboxyl_trans 0.4 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01636 0.2 - - - - 0.6 0.6 0.6 0.6 - 0.6 - 0.6 none 1.0 0 0 143233 113433 0 0 0 0 0 0 0 0 0 57659 0 0 0 0 0 0 255594 0 0 0 0 0 49296 0 59190 0 0 0 237949 147978 0 0 0 473662 0 0 462481 85897 0 0 0 0 0 0 0 0 0 125981 0 0 0 0 0 0 173108 0 0 0 0 0 375178 0 437924 0 0 0 411095 404176 0 0 0 383466 0 0 224786 0 0 0 0 0 0 0 0 0 0 241603 0 0 0 0 0 0 41245 0 0 0 0 0 209737 0 94333 0 0 0 66808 105253 0 0 0 195298 0 0 283338 175487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 325054 0 0 0 0 304348 0 0 675458 685297 0 0 0 0 0 0 0 0 0 1174139 0 0 0 0 0 0 466364 0 0 0 0 0 639309 0 845728 0 0 0 999379 729379 0 0 0 678532 +AAAGAAGAVAVK MGYG000001300_00242;MGYG000003166_01306 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00242 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 443642 0 240592 606109 0 256750 514399 343302 470325 0 0 236984 152432 407409 0 233013 161172 0 750275 649024 0 267120 0 401523 325738 396870 0 0 0 286466 0 0 345105 0 0 0 356836 207703 5953683 0 5754426 5292035 0 4038380 5419772 2993763 4327985 0 0 4660063 3602626 5211233 0 3140115 6108130 0 5736844 4397347 0 2529299 0 3212633 6623875 5039173 0 0 0 3254175 0 0 5023956 0 0 0 5702754 4342954 538363 0 376455 960401 0 312885 931005 0 577942 0 0 381088 586131 549481 0 506240 361392 0 329011 577901 0 0 0 413235 297975 418394 0 0 0 407687 0 0 254485 0 0 0 501401 422768 2170248 0 3307321 1813316 0 2784574 3413583 1579440 2278129 0 0 3542249 2641215 1543098 0 1850765 2244330 0 2355011 1817517 0 2297621 0 2329467 2165959 2177602 0 0 0 2354117 0 0 2954134 0 0 0 2434501 2395270 954280 0 896757 792324 0 117721 415310 1047698 1025392 0 0 0 0 699024 0 0 1063368 0 685949 845079 0 833931 0 179839 815161 904889 0 0 0 0 0 0 255657 0 0 0 1124018 992714 +AAAGAATEVDLK MGYG000001300_00298 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0427@1|root,COG0427@2|Bacteria,1TPHC@1239|Firmicutes,247V0@186801|Clostridia,3WGGE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acetyl-CoA hydrolase/transferase C-terminal domain 1.0 cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AcetylCoA_hyd_C,AcetylCoA_hydro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00298 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 2854738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4778309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342865 0 0 0 0 0 +AAAGAGEAAEEKDEFDVELTEVGPNKVK MGYG000000002_03606 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A faecis|m__MGYG000000002 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,27N7Q@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000002_03606 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 806211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520989 0 557044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 323282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGAGQNFSLGK MGYG000001313_01386 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG1629@1|root,COG4771@2|Bacteria,4NF66@976|Bacteroidetes,2FKYY@200643|Bacteroidia,4AN2X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarboxypepD_reg,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_01386 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 375671 0 0 0 0 0 0 0 2245603 0 0 0 0 348218 0 0 0 0 1218108 0 0 883426 0 0 0 0 304369 0 0 0 0 0 0 0 0 0 0 0 2144667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2157087 0 0 0 0 0 0 0 0 0 0 855202 1410218 0 0 0 0 0 0 0 1734508 0 0 0 0 1285676 0 0 0 0 0 0 0 1076067 0 0 0 0 1100859 0 0 0 0 0 0 0 0 0 0 986264 1625634 0 0 0 0 0 0 0 573299 0 0 0 0 0 0 0 0 0 18535557 0 0 1913907 0 0 0 0 805009 0 0 0 0 0 0 0 0 0 0 0 502535 0 0 0 0 0 0 0 0 0 0 0 0 695209 0 0 0 0 0 0 0 0 0 0 0 0 245244 0 0 +AAAGAGSIQVK MGYG000000249_01881 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_01881 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4741611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGDQLQEWANR MGYG000002517_01937 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia 1.0 186801|Clostridia 1.0 U 1.0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) 1.0 ftsY 1.0 - 1.0 - 1.0 ko:K03110 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SRP54,SRP54_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01937 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03110:ftsY; fused signal recognition particle receptor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 487943 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGEAAAAEK MGYG000001302.1_00066 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_00066 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1433577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1559490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4006368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGEIIVIDSIK MGYG000004487_01021 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900547745|m__MGYG000004487 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,2N6EK@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein L4/L1 family 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004487_01021 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 422117 303372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762985 0 0 551706 0 0 0 0 0 0 0 316224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383828 320981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318179 0 0 406474 0 0 0 0 0 0 0 380389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGEIIVVDSIK MGYG000002926_00535 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,2N6EK@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein L4/L1 family 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_00535 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 709875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300792 0 0 0 0 0 0 0 0 0 0 529433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437854 0 0 0 0 0 0 0 0 0 0 0 0 968805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 651565 0 0 0 0 0 0 0 0 0 0 621530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGEQLSQWADR MGYG000000133_01477 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3XZT9@572511|Blautia 1.0 186801|Clostridia 1.0 U 1.0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) 1.0 ftsY 1.0 - 1.0 - 1.0 ko:K03110 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SRP54,SRP54_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01477 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03110:ftsY; fused signal recognition particle receptor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1160016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGEQLTEWANR MGYG000001338_01473 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3XZT9@572511|Blautia 1.0 186801|Clostridia 1.0 U 1.0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) 1.0 ftsY 1.0 - 1.0 - 1.0 ko:K03110 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SRP54,SRP54_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01473 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03110:ftsY; fused signal recognition particle receptor 1.0 none 1.0 0 263053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 555973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGGFQYR MGYG000001757_00012 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Ruminococcus|s__Ruminococcus sp900540005|m__MGYG000001757 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001757_00012 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3722314 0 0 0 0 2731287 0 0 0 0 3848436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 549006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGILEQQIH MGYG000000171_00267 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 - 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_00267 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01872:AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2628505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGILEQQLH MGYG000000212_00751 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 - 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_00751 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01872:AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 963241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2664424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2086270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGISETLLR MGYG000002494_01913 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0626@1|root,COG0626@2|Bacteria,1MU57@1224|Proteobacteria,1RMCV@1236|Gammaproteobacteria,3XNGS@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the formation of L-cystathionine from O- succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma- replacement reaction. In the absence of thiol, catalyzes gamma- elimination to form 2-oxobutanoate, succinate and ammonia 1.0 metB 1.0 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.5.1.48 1.0 ko:K01739 1.0 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 1.0 M00017 1.0 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 1.0 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iAF1260.b3939,iBWG_1329.BWG_3608,iECDH10B_1368.ECDH10B_4128,iECDH1ME8569_1439.ECDH1ME8569_3808,iETEC_1333.ETEC_4208,iEcDH1_1363.EcDH1_4046,iEcHS_1320.EcHS_A4172,iEcolC_1368.EcolC_4076,iJO1366.b3939,iJR904.b3939,iUMNK88_1353.UMNK88_4777,iUTI89_1310.UTI89_C4524,iY75_1357.Y75_RS17365 1.0 Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01913 1.0 cystathionine gamma-synthase. O-succinyl-L-homoserine succinate-lyase (adding cysteine). Also reacts with H2S and methanethiol as replacing agents, producing homocysteine and methionine, respectively.-!-In the absence of thiol, can also catalyze beta,gamma-elimination to form 2-oxobutanoate, succinate and ammonia.-!-Formerly EC 4.2.99.9. L-cysteine + O-succinyl-L-homoserine = H(+) + L,L-cystathionine + succinate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Selenocompound metabolism|Sulfur metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K01739:metB; cystathionine gamma-synthase [EC:2.5.1.48] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1349685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1595557 0 1592374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 404700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471009 0 1058640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGN(Deamidated)IIPSSTGAAK MGYG000004822_01148;MGYG000004757_00364;MGYG000002006_01638;MGYG000001661_02632;MGYG000001749_01249;MGYG000000254_01186;MGYG000004734_01400;MGYG000003697_01698;MGYG000004760_00889;MGYG000004487_00117;MGYG000000086_02423;MGYG000000390_01195;MGYG000002293_01263;MGYG000001608_00559;MGYG000004779_01244;MGYG000004638_00838;MGYG000000377_02142;MGYG000002067_00330;MGYG000003155_00741;MGYG000002834_00628;MGYG000003681_00790;MGYG000002944_01470 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.22727272727272727 976|Bacteroidetes 0.5 G 0.6363636363636364 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8181818181818182 gap 0.9090909090909091 - 0.9090909090909091 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9090909090909091 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004822_01148 0.045454545454545456 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGNADDIRPC(Carbamidomethyl)IGC(Carbamidomethyl)LR MGYG000004681_00166 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__|m__MGYG000004681 1.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CU83@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 NADH flavin oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Oxidored_FMN,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004681_00166 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGNIIPSST MGYG000002293_01263;MGYG000004734_01400;MGYG000003697_01698 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 0.6666666666666666 G 0.6666666666666666 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01263 0.3333333333333333 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 685412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2694764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAGNIIPSSTGAAK MGYG000004822_01148;MGYG000004757_00364;MGYG000002006_01638;MGYG000001661_02632;MGYG000001749_01249;MGYG000000254_01186;MGYG000004734_01400;MGYG000003697_01698;MGYG000004760_00889;MGYG000004487_00117;MGYG000000086_02423;MGYG000000390_01195;MGYG000002293_01263;MGYG000001608_00559;MGYG000004779_01244;MGYG000004638_00838;MGYG000000377_02142;MGYG000002067_00330;MGYG000003155_00741;MGYG000002834_00628;MGYG000003681_00790;MGYG000002944_01470 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.22727272727272727 976|Bacteroidetes 0.5 G 0.6363636363636364 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8181818181818182 gap 0.9090909090909091 - 0.9090909090909091 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9090909090909091 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004822_01148 0.045454545454545456 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 1208302 1398580 996376 1438592 1284590 1232802 1244629 1350206 1104610 1168589 965318 1125453 1179756 1120189 1186032 0 1162544 989529 1303395 1663503 1491806 896306 1004488 1290257 1372153 1201705 1400235 1124197 1389158 1023299 980068 1389404 1136859 1139238 1395473 1346093 1262886 1031820 8960311 3895674 7222117 7884147 6451408 0 6311214 9213933 9831713 10658312 0 7480150 6152304 9880014 8381763 5932909 6787441 7856578 7592301 8215187 7808634 7246072 0 5123885 7883816 8572780 9018457 8637970 6267733 9158596 4447209 6609318 5974218 8551197 9984561 8696435 9873733 7996450 2511252 2826472 2947643 2959899 3559052 0 3101771 2411292 2601581 2245894 0 2685859 0 2628925 2026926 3170334 3054373 7230293 2529195 2671237 2489822 0 5743961 3226962 2334692 2482048 2518250 4965015 2871380 2434263 3685277 3934920 2692904 2269463 2102741 3151141 2503727 2792950 16226527 9746170 32844169 10088558 16867352 33456789 15120703 22387073 13701130 9167241 24087727 19642096 19393677 12327934 16289960 14627876 9514163 17281592 8129363 8588104 11851068 34810225 28411705 15853263 19877043 20159078 14348778 1592312 7349969 8016819 10137842 18784762 32635755 35001557 18896936 20205838 19455801 20876257 1286216 850094 1010183 1583271 1319110 1343268 1640217 2229223 1515785 1610595 819439 1004340 1662542 1076722 1287085 1581702 0 3814648 1313051 1679643 1187467 970086 2793102 1044121 1799986 1301449 1249695 2536966 1502435 1742825 1346193 1170555 952073 2088636 1862911 1331943 1493486 1115027 +AAAGVILITTK MGYG000001562_01245;MGYG000004876_01631;MGYG000000825_00527;MGYG000002717_02046;MGYG000002478_00534;MGYG000003701_02597;MGYG000001562_02036;MGYG000001789_02639;MGYG000000054_02947;MGYG000002007_00083 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.4 976|Bacteroidetes 1.0 P 0.9 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001562_01245 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 388416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318887 0 637366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656169 0 933368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAHEIMDTVLAGDAYK MGYG000001658_01423 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01|s__SFFH01 sp900548125|m__MGYG000001658 1.0 COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1UJBN@1239|Firmicutes,24QYH@186801|Clostridia,26C5N@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,FAD_binding_2,FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001658_01423 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1157864 0 0 0 0 2966361 0 0 0 0 639093 835185 0 0 0 0 0 0 0 0 0 +AAAHMVDEVRR MGYG000001661_00238 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides gallinarum|m__MGYG000001661 1.0 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,4AKW4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane 1.0 hppA 1.0 - 1.0 3.6.1.1 1.0 ko:K15987 1.0 ko00190,map00190 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 3.A.10.1 1.0 - 1.0 - 1.0 H_PPase,OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001661_00238 1.0 inorganic diphosphatase. pyrophosphate phosphohydrolase. Specificity varies with the source and with the activating metal ion.-!-The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9. cf. EC 7.1.3.1. diphosphate + H2O = H(+) + 2 phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation 1.0 K15987:hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 85023 0 142730 0 0 0 0 0 0 58676 0 0 0 0 0 0 0 0 0 0 580176 0 613070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347937 0 439364 0 0 0 0 0 0 494092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138764 0 0 0 0 0 0 0 +AAAIALDIPLYR MGYG000002517_02082 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000002517_02082 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 339236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133524 0 0 0 0 385331 0 0 0 0 117237 0 0 0 0 323683 0 0 0 0 247422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 674006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283704 2700551 0 0 0 493296 0 0 0 0 502733 0 0 0 0 630082 0 0 0 0 294399 +AAAIC(Carbamidomethyl)AER MGYG000002506_01784;MGYG000002494_03864;MGYG000002534_03414 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,1QTS5@1224|Proteobacteria,1RMJS@1236|Gammaproteobacteria 0.6666666666666666 1236|Gammaproteobacteria 1.0 C 0.6666666666666666 belongs to the CobB CobQ family 1.0 pta 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006083,GO:0006084,GO:0006085,GO:0006091,GO:0006113,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006566,GO:0006567,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008959,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015980,GO:0016053,GO:0016054,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0016999,GO:0017000,GO:0017001,GO:0017144,GO:0018130,GO:0019413,GO:0019427,GO:0019438,GO:0019541,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045733,GO:0046390,GO:0046394,GO:0046395,GO:0046459,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070689,GO:0071616,GO:0071704,GO:0072329,GO:0072330,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.0 2.3.1.8 1.0 ko:K13788 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iG2583_1286.G2583_2834,iYL1228.KPN_02688 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_01784 0.3333333333333333 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K13788:pta; phosphate acetyltransferase [EC:2.3.1.8] 1.0 none 1.0 0 1036383 1071481 0 1202497 1305528 1620279 0 0 1228769 0 0 2081650 1207197 1044656 1359136 982636 0 1329548 689586 1137720 1532765 0 2284194 1263976 0 0 0 1552100 0 0 1430021 1184085 0 0 0 0 1179076 0 2634145 1623492 0 2043697 4261583 2209478 0 0 2796316 0 0 1780545 2703372 1481410 2052795 3003217 0 2543133 1588760 2777190 5588779 0 4085878 2279654 0 0 0 3100616 0 0 1835738 2542364 0 0 0 0 1836587 0 895501 964161 0 991973 2472597 1761022 0 0 1719655 0 0 1319514 1297384 1354020 1487841 803231 0 1408813 1482950 1331319 1788217 0 1978756 1772984 0 0 0 908557 0 0 1255399 1156555 0 0 0 0 833743 0 629938 1194542 0 804932 1650084 997270 0 0 1251696 0 0 897703 816655 985651 634334 557776 0 805189 723709 548272 1560703 0 1470070 910475 0 0 0 803674 0 0 722124 1726122 0 0 0 0 795703 0 362603 307722 0 1387784 528170 274592 0 0 315711 0 0 681591 287486 261369 1225145 409350 0 583152 697263 126251 513231 0 655113 443458 0 0 0 414160 0 0 74132 373373 0 0 0 0 681204 +AAAIC(Carbamidomethyl)GADMK MGYG000000258_00350;MGYG000002528_01331 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,2493N@186801|Clostridia,27TH1@186928|unclassified Lachnospiraceae 0.5 186801|Clostridia 1.0 E 1.0 Glucose dehydrogenase C-terminus 0.5 - 1.0 - 1.0 1.1.1.103,1.1.1.14 0.5 ko:K00008,ko:K00060 0.5 ko00040,ko00051,ko00260,ko01100,map00040,map00051,map00260,map01100 0.5 M00014 0.5 R00875,R01465,R01896 0.5 RC00085,RC00102,RC00525 0.5 ko00000,ko00001,ko00002,ko01000 0.5 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00350 0.5 L-threonine 3-dehydrogenase. | L-iditol 2-dehydrogenase. TDH. | sorbitol dehydrogenase. Acts in concert with EC 2.3.1.29 in the degradation of threonine to glycine.-!-This threonine-degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex.-!-In aqueous solution, the product L-2-amino-3-oxobutanoate can spontaneously decarboxylate to form aminoacetone. | This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-threonine + NAD(+) = (2S)-2-amino-3-oxobutanoate + H(+) + NADH. | L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 0.5 0.5 0.5 0.5 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Glycine, serine and threonine metabolism|Metabolic pathways 0.5 K00008:SORD, gutB; L-iditol 2-dehydrogenase [EC:1.1.1.14]|K00060:tdh; threonine 3-dehydrogenase [EC:1.1.1.103] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 993377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAIELIK MGYG000003266_00144;MGYG000000188_00406;MGYG000000802_00030;MGYG000001086_00655 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1925@1|root,COG1925@2|Bacteria,2H0K7@201174|Actinobacteria,4CWQ1@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 PTS HPr component phosphorylation site 1.0 - 1.0 - 1.0 - 1.0 ko:K11189 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003266_00144 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K11189:- 1.0 none 1.0 0 2262068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2587794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1144473 0 0 0 0 0 0 0 0 0 0 1989206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1362722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1831425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAIGEMTYGAAR MGYG000002281_03314;MGYG000002171_03031;MGYG000000196_02520;MGYG000000013_04059;MGYG000002438_00951;MGYG000000243_01803;MGYG000002549_04632;MGYG000004797_03291;MGYG000001313_00778;MGYG000000105_03290;MGYG000001666_00135;MGYG000002478_00220;MGYG000004876_01712 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,4AMRT@815|Bacteroidaceae 0.8461538461538461 976|Bacteroidetes 1.0 GK 0.8461538461538461 Psort location Cytoplasmic, score 9.26 0.8461538461538461 glk 0.9230769230769231 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_03314 0.07692307692307693 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Galactose metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Neomycin, kanamycin and gentamicin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00845:glk; glucokinase [EC:2.7.1.2] 1.0 none 1.0 258108 0 388779 0 295158 159845 291620 243841 249709 0 323730 384280 0 351509 0 297084 0 511724 302739 257819 352652 421580 438568 431983 0 294220 296528 168744 0 162021 0 0 335190 287024 0 302451 313485 360369 400760 0 357565 0 299827 324145 418841 408283 456465 349942 246875 268135 384617 301152 0 174867 0 172573 548006 519357 543182 304306 359205 322448 0 432117 370459 1168619 0 376896 0 0 500551 518627 0 474857 583869 580171 1212196 0 1739426 0 1715284 1183649 1358170 1143809 1535797 1018023 1114298 918200 956795 1124602 0 737391 0 1268042 1178303 1495932 1289618 584498 866996 1163250 0 1056832 981278 815239 0 1594732 0 0 1025877 956182 0 1869931 1239599 1136756 352447 0 605546 0 675054 593727 559812 347839 834623 737239 637933 456842 595215 640221 0 654496 0 480981 1049342 535207 760233 505394 0 604430 0 0 582872 709321 0 422153 0 0 617688 0 0 553149 457829 507469 1004393 0 992360 0 1236487 1235279 1056000 802778 953051 941074 609788 1215204 953944 751479 0 1095162 0 288820 1325819 0 765533 704310 0 1027936 0 1059350 1201802 0 0 987298 0 0 556778 431346 0 866041 747593 1007843 +AAAILAARPENK MGYG000002517_02918 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the cysteine synthase cystathionine beta- synthase family 1.0 cysK 1.0 - 1.0 2.5.1.47 1.0 ko:K01738 1.0 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00021 1.0 R00897,R03601,R04859 1.0 RC00020,RC02814,RC02821 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PALP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02918 1.0 cysteine synthase. OAS sulfhydrylase. Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors.-!-Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53.-!-Formerly EC 4.2.99.8. hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Sulfur metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01738:cysK; cysteine synthase [EC:2.5.1.47] 1.0 none 1.0 2096865 0 293972 118942 259217 328626 0 0 293006 0 177878 320652 0 1157781 945801 379761 510269 0 0 1039627 2486115 173117 0 367545 798295 1325387 0 0 0 356571 0 0 224666 0 0 1758280 1597423 294085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9713899 0 0 9054916 301523 0 0 0 1549437 0 0 0 0 4508718 2771942 0 935180 0 0 2535667 955721 0 0 0 2477136 5451342 8739687 0 0 4006875 0 0 0 3325674 0 8981464 2136955 0 650514 14507054 10252410 0 10226129 6108645 0 0 403227 0 2219552 14791854 0 477612 1360759 17274398 6615189 0 0 279781 13255993 12812775 0 13106943 553565 634959 606003 0 0 653434 7995894 672748 9693352 578175 0 1007241 611563 13645157 +AAAILDKLGVEYEMK MGYG000000301_01054;MGYG000000133_02573 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3XZ51@572511|Blautia 0.5 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) 1.0 purE 1.0 - 1.0 5.4.99.18 1.0 ko:K01588 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R07405 1.0 RC01947 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_01054 0.5 5-(carboxyamino)imidazole ribonucleotide mutase. N(5)-carboxyaminoimidazole ribonucleotide mutase. In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates.-!-In the absence of EC 6.3.2.6, the reaction is reversible.-!-The substrate is readily converted into 5-amino-1-(5-phospho-D- ribosyl)imidazole by non-enzymic decarboxylation. 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1- (5-phospho-D-ribosyl)imidazole-4-carboxylate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01588:purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] 1.0 none 1.0 0 0 0 0 0 67365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 65723 0 91096 0 0 0 0 0 0 0 0 0 0 59693 173299 0 0 110319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76429 0 0 0 0 0 0 0 0 0 93993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70438 0 0 0 0 0 0 0 0 0 609635 663680 908741 835874 0 507117 683952 408616 409145 1065160 1090655 437130 579502 1273057 718193 466489 707228 0 0 0 709774 624603 0 583053 645794 517913 717145 0 1160438 0 658833 1075080 1167347 0 489078 675698 406042 515876 +AAAINIIPTTTGAAK MGYG000001881_00319 genome d__Bacteria|p__Verrucomicrobiota|c__Verrucomicrobiae|o__Verrucomicrobiales|f__Akkermansiaceae|g__Akkermansia|s__Akkermansia muciniphila_A|m__MGYG000001881 1.0 COG0057@1|root,COG0057@2|Bacteria,46S59@74201|Verrucomicrobia,2ITXT@203494|Verrucomicrobiae 1.0 203494|Verrucomicrobiae 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 - 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001881_00319 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1221977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAINIVPN(Deamidated)STGAAK MGYG000000205_02269;MGYG000003335_00316;MGYG000000233_00345;MGYG000002972_00451 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.75 186801|Clostridia 0.75 C 1.0 Psort location Cytoplasmic, score 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447079 520944 0 0 0 0 0 448183 438134 0 0 0 0 0 0 0 593835 0 583202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460675 0 0 0 0 0 0 205716 235515 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAINIVPNSTGAAK MGYG000000205_02269;MGYG000003335_00316;MGYG000000233_00345;MGYG000002972_00451 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.75 186801|Clostridia 0.75 C 1.0 Psort location Cytoplasmic, score 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 1671106 1483025 902833 1418563 839206 982663 1148308 2275419 1160842 1554201 868726 1394595 931138 925305 897079 942570 1252966 235035 696777 900925 1442725 1367217 454859 917241 1285976 995780 1458898 237028 1439492 1182980 495994 991372 741817 1276594 1718585 1617511 1082089 671390 7669481 5988828 3850095 10004706 0 3463577 8361955 7842124 6593867 8848448 4281051 4983082 5110802 6439611 0 3902677 0 822530 5537262 7887674 5853589 0 542302 4859372 5239423 5858276 5531968 696498 8468317 5299207 5581156 3810977 6460706 0 7621782 8817022 5056327 4436412 997751 1806872 405527 653220 283221 597469 623356 1410306 394333 839109 637104 451848 588232 572499 912555 937317 778395 581480 1653685 1233608 718757 1190577 641102 600767 639211 621454 1376836 949403 1013839 989416 559475 1635466 1012782 2038709 1222897 669765 584518 410318 592815 0 0 0 0 0 0 311192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392477 263750 0 0 0 0 0 0 0 480209 553324 306919 172292 0 1335497 2346577 1921116 0 1642588 1657490 2482824 3115708 1593459 2113268 2005375 0 972761 2572817 2212898 2185600 2158361 689411 2121758 1291705 1638903 2411516 995739 3655773 2364022 1481567 0 780537 2921955 1022376 2378605 1377382 2073260 0 1871339 1689777 0 2153118 +AAAINTIAHSTGAAK MGYG000002469_01340;MGYG000001292_00923 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CZ97@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002469_01340 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 1411858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3224561 3718861 0 0 0 2547187 0 0 0 0 0 0 0 0 0 0 0 10404354 0 0 0 1608314 3287842 3266339 0 2995999 0 5775052 3702422 0 3813839 0 0 0 3918781 0 3195641 0 0 182664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 508534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 870250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAINTIPHSTGAAK MGYG000003683_00168;MGYG000002459_01163;MGYG000000756_01094;MGYG000001490_01234 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,4CZ97@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00168 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 805512 0 0 1074434 0 0 0 0 0 0 117590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1803786 2501816 3782674 0 2042527 3894507 2173386 1697038 0 1933163 2443839 0 7710181 1204103 0 2423094 0 9468343 0 0 0 1925403 2627586 6824319 1868871 1587427 1643413 6042706 2608892 0 4805510 0 3393916 2502741 2114096 0 1755700 4650468 848860 1956081 677675 0 0 387366 0 1065418 0 779579 610112 0 803377 447718 0 1147453 0 193383 0 0 0 1431517 176500 0 590697 612397 1098271 1153311 509557 0 330215 0 1967258 1525961 1518205 0 561970 472052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAISTGAK MGYG000001346_02120 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,2FME7@200643|Bacteroidia,4AKME@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin 1.0 oorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00175 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_02120 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00175:korB, oorB, oforB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 903376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2850139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAISTGC(Carbamidomethyl)K MGYG000000243_01840;MGYG000004899_00389;MGYG000002455_01429;MGYG000004797_02543;MGYG000002478_01476;MGYG000004876_03121 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1013@1|root,COG1013@2|Bacteria,4NIE0@976|Bacteroidetes,2FME7@200643|Bacteroidia,4AKME@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin 0.6666666666666666 oorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00175 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01840 0.16666666666666666 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00175:korB, oorB, oforB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11] 1.0 none 1.0 1448124 1084442 2554764 1836526 785315 1219434 2099153 493352 1884908 597704 0 342705 1549257 590358 0 493218 0 0 528422 1249823 1994124 509969 604950 2100740 1426056 1906890 1966074 0 1426911 748884 2180601 1430312 3423738 480011 0 1918137 1673563 2469826 0 0 0 0 353395 527609 0 0 0 0 0 0 1398020 754970 0 900496 0 0 840237 893075 770721 641782 0 0 0 0 0 0 652889 717019 0 0 0 0 0 0 0 523966 150247 119297 173206 82790 62325 130329 0 0 265985 149581 0 78957 111001 0 0 0 0 169753 227579 188935 97561 196700 56489 552684 0 390959 518166 0 375108 0 0 324144 0 57298 0 98718 135049 135626 394501 270023 169851 0 290159 202066 163759 295008 236980 321158 0 0 124794 553313 0 101947 0 413143 501589 525746 0 0 0 0 268355 317577 0 501559 186136 167663 0 220726 242439 477087 0 0 221337 0 949952 592864 876955 708697 1070505 1243342 1481949 981725 1530791 181205 0 931335 1084952 592196 0 1175663 0 1304473 1260354 1144851 705027 878730 368162 1208257 1198184 1836990 909357 126859 1235968 1066677 1770371 735727 608041 1362405 0 1726950 1874613 1190688 +AAAIVTNR MGYG000002494_00968 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,1RP3T@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate 1.0 ppsA 1.0 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 1.0 2.7.9.2 1.0 ko:K01007 1.0 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 1.0 M00173,M00374 1.0 R00199 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1919,iYL1228.KPN_02160 1.0 Intein_splicing,PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00968 1.0 pyruvate, water dikinase. pyruvate,water dikinase. - ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01007:pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAKTETVKDTAAETK MGYG000000076_01972 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia intestinalis|m__MGYG000000076 1.0 2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000076_01972 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 173388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 558063 0 0 0 0 0 0 395877 0 0 0 566534 0 0 0 0 0 0 464818 0 0 0 0 0 689235 692647 0 0 0 0 0 0 0 0 0 0 541514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAALAAADAR MGYG000002323_02346;MGYG000001302.1_01840;MGYG000002415_02605;MGYG000000093_03243;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206;MGYG000002534_02768;MGYG000003883_03730 domain d__Bacteria 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 0.8888888888888888 C 0.8888888888888888 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.6666666666666666 adhE 0.8888888888888888 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 0.8888888888888888 1.1.1.1,1.2.1.10 0.8888888888888888 ko:K04072 0.8888888888888888 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 0.8888888888888888 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 0.8888888888888888 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 0.8888888888888888 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 0.8888888888888888 Aldedh,Fe-ADH 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_02346 0.1111111111111111 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 0.8888888888888888 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 0.8888888888888888 none 1.0 3215553 3477574 4520840 2599046 2064233 13666351 4071204 3296217 2438300 3589759 1095129 2154760 1470674 3121115 2454750 1245219 1835491 0 2279825 3250700 3166851 14672284 0 13378778 3692433 2257396 2538294 0 3530038 3340620 2287215 2869247 4522779 3452808 4358092 2393737 3126510 4617229 62037313 69578930 77119213 43883144 58881771 86561138 70499659 33926506 63246263 62529791 15880986 37231262 27230395 61574903 49150128 36543487 72324100 0 72446539 49804702 71256936 108276081 0 85382007 68635808 50383261 38500572 0 86319010 63839106 23919671 32059834 82175386 56109795 50037721 50336308 53870785 63400878 4959265 4687426 7598748 4250068 3726102 20691302 4987032 5818874 3374931 5123489 3081266 2179731 4289601 3690001 3615326 4237620 3301256 0 4185748 0 3741741 16951644 0 17102858 4923684 3391692 5159393 0 3624926 4064393 3849843 3250886 8215040 6745440 3306923 0 3299387 7623448 6723046 3001993 6103013 4983947 3404780 7571818 4973659 5728887 3703844 5008436 2169549 3014042 3678522 4912652 4335857 3535671 2927623 0 3598520 4728966 4401889 8864164 0 4864967 4952329 4095118 6167001 0 3062400 4420584 1596522 2529640 5680649 8941572 9163455 7223090 3938924 4019400 109989 90102 182342 0 310507 0 0 120812 0 0 0 0 0 0 0 0 0 0 0 0 0 346650 0 0 0 0 97082 0 0 0 0 0 0 0 0 0 580079 0 +AAALEKVK MGYG000000233_00634 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,220M9@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Binds together with S18 to 16S ribosomal RNA 1.0 rpsF 1.0 - 1.0 - 1.0 ko:K02990 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_00634 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02990:RP-S6, MRPS6, rpsF; small subunit ribosomal protein S6 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3329811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3647310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAALETDVVEK MGYG000004876_03560 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__|m__MGYG000004876 1.0 COG0475@1|root,COG0490@1|root,COG0475@2|Bacteria,COG0490@2|Bacteria,4NGF6@976|Bacteroidetes,2FNTX@200643|Bacteroidia,4AKY2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Psort location CytoplasmicMembrane, score 10.00 1.0 nhaA 1.0 - 1.0 - 1.0 ko:K03455 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 2.A.37 1.0 - 1.0 - 1.0 Na_H_Exchanger,TrkA_C,TrkA_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004876_03560 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03455:KEA1_2_3, kefB, kefC; K+:H+ antiporter 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1758996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAALKPGEVLLLENLR MGYG000003693_01612;MGYG000001306_01732;MGYG000002556_00160;MGYG000001599_01138;MGYG000002478_02340 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0745@1|root,COG3292@1|root,COG5002@1|root,COG0745@2|Bacteria,COG3292@2|Bacteria,COG5002@2|Bacteria,4NIEK@976|Bacteroidetes,2FMAP@200643|Bacteroidia,4AKI4@815|Bacteroidaceae 0.6 976|Bacteroidetes 1.0 T 0.6 Psort location CytoplasmicMembrane, score 0.6 - 0.6 - 1.0 - 0.6 - 0.6 - 0.6 - 0.6 - 0.6 - 0.6 - 0.6 - 1.0 - 1.0 - 1.0 HATPase_c,HTH_18,HisKA,Reg_prop,Response_reg,Y_Y_Y 0.6 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_01612 0.2 - - - - 0.6 0.6 0.6 0.6 - 0.6 - 0.6 none 1.0 0 0 0 0 0 0 0 0 0 0 96105 308855 0 0 0 0 0 95798 0 0 0 0 210154 0 0 0 0 76443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 551603 506956 0 0 0 0 0 968768 0 0 0 0 1421986 0 0 0 0 1252664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117803 236397 0 0 0 0 0 331707 0 0 0 0 71284 0 0 0 0 249948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151750 104592 0 0 0 0 0 107662 0 0 0 0 128788 0 0 0 0 61283 0 0 0 0 0 0 0 0 0 0 +AAALLGK MGYG000001502_02294 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Intestinimonas|s__Intestinimonas massiliensis|m__MGYG000001502 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,267UV@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001502_02294 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAALNIVPN(Deamidated)STGAAK MGYG000000205_02269;MGYG000001303_01883;MGYG000000233_00345;MGYG000001496_01122 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.75 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 701351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAALNIVPNSTGAAK MGYG000000205_02269;MGYG000001303_01883;MGYG000000233_00345;MGYG000001496_01122 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.75 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5071814 0 0 0 0 0 0 0 0 0 6164324 0 5200537 0 0 0 0 2779568 0 0 0 0 0 0 0 0 0 0 0 9043641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471645 0 0 0 0 0 0 0 2802199 0 0 0 0 0 0 0 2815557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1877558 0 0 0 0 0 0 2771071 0 0 1518321 0 +AAALQLK MGYG000002867_00481 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes sp900552955|m__MGYG000002867 1.0 COG0544@1|root,COG0544@2|Bacteria,4NE99@976|Bacteroidetes,2FM7B@200643|Bacteroidia,22U1P@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Bacterial trigger factor protein (TF) 1.0 tig 1.0 - 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002867_00481 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAALQPGEALLLENLR MGYG000002438_03839;MGYG000001489_04176 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,22WBD@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03839 0.5 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14179812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16029107 0 0 0 0 0 0 0 0 16113959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAALQPGEVLLLENLR MGYG000000196_04506;MGYG000000013_01224;MGYG000003681_00986;MGYG000002549_02739;MGYG000001661_02348;MGYG000003922_03393;MGYG000004876_02584 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04506 0.14285714285714285 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2348550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15939497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16403880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAALSQDDK MGYG000000251_00650 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter saccharivorans|m__MGYG000000251 1.0 COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase delta subunit 1.0 acsD 1.0 - 1.0 2.1.1.245 1.0 ko:K00194 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_00650 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00194:cdhD, acsD; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit delta [EC:2.1.1.245] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2058015 0 0 0 0 0 15186338 0 0 0 0 36377799 0 0 0 0 32636038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 695508 0 0 0 0 0 0 0 0 0 0 524496 0 0 0 0 889517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 508044 0 0 0 0 0 0 0 0 0 273729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252500 0 0 0 0 0 0 0 0 0 0 347791 0 0 0 0 148804 0 0 0 0 0 0 0 0 0 0 +AAALTQAK MGYG000001306_00758 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG1726@1|root,COG1726@2|Bacteria,4NEDQ@976|Bacteroidetes,2FN6J@200643|Bacteroidia,4AK9W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrA 1.0 - 1.0 1.6.5.8 1.0 ko:K00346 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQRA,NQRA_SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_00758 1.0 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 - 1.0 K00346:nqrA; Na+-transporting NADH:ubiquinone oxidoreductase subunit A [EC:7.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309725 0 0 0 0 484079 0 0 0 0 643247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1772760 0 0 0 0 3527302 0 0 0 0 3948786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34388 0 0 0 0 282765 0 0 0 0 710618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175233 0 0 0 0 396986 0 0 0 0 348692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596376 0 0 0 0 367478 0 0 0 0 145021 0 0 0 0 0 0 0 0 0 0 +AAAMLGKPIEELK MGYG000000099_02082 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,267UV@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_02082 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAMSGAVGIR MGYG000002274_02046;MGYG000004679_00371;MGYG000002619_01820;MGYG000000195_01824;MGYG000002040_00364;MGYG000003166_00931;MGYG000000022_01123 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,3WJ12@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) 1.0 nanE 1.0 - 1.0 5.1.3.9 1.0 ko:K01788 1.0 ko00520,map00520 1.0 - 1.0 R02087 1.0 RC00290 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 NanE,PTS_EIIA_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_02046 0.14285714285714285 N-acylglucosamine-6-phosphate 2-epimerase. N-acetylmannosamine-6-phosphate 2-epimerase. - an N-acyl-D-glucosamine 6-phosphate = an N-acyl-D-mannosamine 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 K01788:nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409920 0 0 0 0 429571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1501560 0 0 0 0 1608865 0 0 0 0 2027686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2665203 0 0 0 0 2748789 0 0 0 0 1857452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1129607 0 0 0 0 1569672 0 0 0 0 1176609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1886461 0 0 0 0 1475451 0 0 0 0 1804926 0 0 0 0 0 0 0 0 0 0 +AAAMSIIPTTTGAAK MGYG000004769_01658 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H298@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01658 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 911926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 953406 0 1068968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAN(Deamidated)ATGYDVVLGTSSK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03061 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 497764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 717898 0 0 0 0 933644 0 0 0 0 407551 0 0 0 0 368027 0 0 0 0 512121 +AAAN(Deamidated)ATGYDVVLGTSSKK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03061 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635024 854777 0 0 0 0 0 0 +AAAN(Deamidated)ESFGYNEDEIVSSDIVGM(Oxidation)R MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAN(Deamidated)ESFGYNEDEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANAPEQEYR MGYG000000271_02405 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Myosin-crossreactive antigen 1.0 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02405 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 - 1.0 K10254:ohyA, sph; oleate hydratase [EC:4.2.1.53] 1.0 none 1.0 294185 0 0 0 0 394864 170890 0 222983 0 814968 629107 0 0 0 0 0 0 128278 148369 0 284116 0 287350 195204 281969 0 0 0 1332248 0 0 0 0 0 0 302627 0 169788 0 0 0 0 0 0 0 224228 0 0 181924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116385 0 0 159070 0 0 0 0 0 0 0 0 0 0 0 0 0 117622 0 0 0 0 0 0 0 0 0 0 134686 0 346135 0 0 0 0 615327 479888 0 395371 0 450019 1252127 0 0 0 0 0 0 594639 383212 0 449039 0 837883 485056 573270 0 0 0 672088 0 0 0 384229 0 0 423147 0 +AAANATGYD(Cation_Na)VVLGTSSK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03061 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1097135 0 0 0 0 0 0 +AAANATGYDVVL MGYG000001338_03066;MGYG000001338_03061;MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.6666666666666666 2|Bacteria 0.6666666666666666 S 0.6666666666666666 peptidase inhibitor activity 0.6666666666666666 - 1.0 - 1.0 3.4.24.40 0.6666666666666666 ko:K01406 0.6666666666666666 ko01503,map01503 0.6666666666666666 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.6666666666666666 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03066 0.3333333333333333 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Cationic antimicrobial peptide (CAMP) resistance 0.6666666666666666 K01406:prtC; serralysin [EC:3.4.24.40] 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANATGYDVVLGT(Thr->Ala)SSK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03061 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2963902 0 0 0 0 0 1561497 0 0 0 0 0 0 2779973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANATGYDVVLGT(Thr->Ala)SSKK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03061 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 0 0 0 0 3353401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANATGYDVVLGTD(Asp->Gly)SK MGYG000001338_03066;MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 0.5 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03066 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 0 7500133 3618366 0 0 2499828 0 2769525 0 0 4529909 2944667 3439083 0 2234761 0 0 0 0 0 0 2718829 6023168 3810675 0 0 2958158 3804639 0 2945657 10499287 0 3740664 0 0 0 0 0 0 0 5785880 0 0 5241241 0 5690574 0 6004810 11524714 5451823 0 0 5722204 7102471 0 10896667 0 0 0 5471673 0 6046811 0 0 6031697 13036986 0 1684419 0 0 7270069 0 0 0 0 0 0 0 3507104 0 0 3284534 0 0 0 1899955 3704036 0 3121080 0 0 0 0 3186518 0 0 0 2338260 2442384 0 0 0 1451986 2611694 0 1611101 0 0 3176586 0 0 0 0 3464338 0 0 0 0 0 844368 0 1765597 0 0 0 0 1814935 0 1206910 815069 0 0 0 0 0 0 0 503762 0 0 904380 0 0 0 0 0 2377061 0 0 0 0 1181319 0 0 0 0 0 0 0 0 0 668133 0 0 1402175 0 0 0 0 0 0 0 0 0 2550641 0 0 0 0 0 0 0 0 0 2569804 0 0 0 0 0 +AAANATGYDVVLGTD(Asp->Gly)SKK MGYG000001338_03066;MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 0.5 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03066 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 0 6187757 0 0 0 2064201 0 1920139 0 0 3575061 0 2371925 0 0 0 0 0 0 0 0 0 3234285 0 0 0 2709528 0 0 0 9437468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4096563 0 0 0 5022742 0 7524721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2177632 0 0 0 0 978168 0 0 0 0 1791755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920835 0 0 0 0 0 0 0 0 633943 2506252 0 0 0 458047 530991 0 0 0 0 1110378 0 0 0 0 0 +AAANATGYDVVLGTD(Asp->Ser)SK MGYG000001338_03066;MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 0.5 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03066 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 903676 0 0 1995946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANATGYDVVLGTDSK MGYG000001338_03066;MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 0.5 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03066 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 268247 207923 203528 209243 81138 0 375654 144217 0 228088 0 165154 0 0 184420 201014 204803 0 220870 119044 0 334692 229140 235641 127241 307085 225962 0 0 0 226530 303508 0 222711 0 0 111194 0 426760 0 259695 414381 217391 421106 252934 485893 0 294830 133186 595639 411284 0 370873 436585 373087 0 297645 316035 0 705575 569171 0 378302 281251 86716 807168 0 0 204955 250066 162018 278758 0 0 473857 279643 433909 730477 765809 407473 1331414 839875 590448 366927 0 567095 708279 973713 765879 0 350939 877974 474396 1394401 0 450297 0 481078 947104 1044019 446847 578700 435001 939235 0 0 1509909 965847 536149 346820 0 0 663859 589755 106434 0 137230 257235 126073 253434 121529 0 0 0 214249 0 282952 0 0 134072 118748 0 0 0 0 0 342770 0 0 118618 96630 0 0 0 98269 265358 0 234625 0 0 128040 0 1088833 4320606 2559065 1261907 3105403 1401538 1199809 1536386 0 1073263 1727933 1279703 2890463 0 986452 1964970 1104327 2399677 1102101 1322837 0 1236273 2229562 2173463 1099050 1216525 1244803 1774681 0 0 4179869 6398447 2467608 1540142 0 0 1426376 2966492 +AAANATGYDVVLGTDSKK MGYG000001338_03066;MGYG000001338_03072 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 0.5 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03066 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 343727 0 0 0 322642 592717 0 0 0 0 0 0 0 0 0 0 116108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553685 0 288212 0 0 87387 126549 0 0 0 0 0 324922 174167 99644 0 0 283992 207160 0 0 0 0 170415 0 0 0 237588 0 0 0 0 76423 182725 0 417903 0 0 226534 0 226053 348757 747487 319564 757782 452033 0 0 0 0 373866 363794 618349 0 0 669463 793756 617495 0 0 0 0 801978 422177 524050 374373 0 507501 0 0 1242515 1021836 958910 493429 0 0 347380 299745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 982399 3303550 1921583 982518 2418068 1256048 0 0 0 0 1451704 1197314 1338660 0 0 1651315 1596022 1244119 0 0 0 879962 1409931 1362879 859084 913388 0 1169697 0 0 2944022 4243115 2035845 1031476 0 0 756245 1911903 +AAANATGYDVVLGTS(Ser->Gly)SK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03061 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 2612041 0 0 0 4048356 0 0 0 0 2660712 0 0 0 0 0 3324142 3055533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12119300 0 0 0 0 0 0 0 25379992 0 0 9607977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17055775 0 0 5393448 0 0 0 0 0 22461041 0 0 0 0 5216687 5357608 1613836 0 0 0 7817023 0 1769889 1412581 0 0 0 0 0 0 0 2456821 1734652 3491970 1354282 0 0 0 0 0 0 1867359 0 0 0 0 0 9548539 0 0 0 0 1570512 0 0 5933070 0 0 0 0 1260787 0 0 978195 1645501 0 0 0 0 1024205 816041 511083 1071490 0 0 0 913783 0 0 1562508 0 0 0 0 2398394 0 0 0 0 0 0 0 991616 3775196 2731356 913509 0 0 903029 1112327 0 0 0 1202248 0 0 0 0 895055 0 952851 0 0 0 0 0 0 1453959 0 2306787 0 0 3987387 0 0 1185008 0 0 1218075 0 +AAANATGYDVVLGTS(Ser->Gly)SKK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03061 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 2424577 0 2966869 2871518 0 0 0 0 0 2276849 0 2404498 0 0 0 3105039 0 2164568 0 1832619 0 2727444 0 3354584 0 1778364 0 2541251 2520321 0 0 9264030 3801568 0 0 0 2035167 4108888 5721032 0 4319636 4175053 7485613 3559781 0 0 0 3738680 7682312 0 5703998 0 0 0 0 0 0 3567111 0 4664943 7115295 3506267 0 4225098 0 6196969 0 0 0 14530896 4284003 0 0 0 4065086 3941680 808972 6819555 0 1411267 4904938 2216120 0 0 0 1144240 2728520 1430641 0 0 0 2001340 0 2786494 0 566049 0 1498880 2475001 2129173 0 1040183 0 2313102 1362993 0 6064798 8143173 2281423 0 0 0 985615 2164020 364403 716247 0 0 172990 0 0 0 0 0 0 1045668 963834 0 0 0 0 0 0 0 0 0 0 0 0 833067 0 0 0 0 0 2564935 0 0 0 0 439180 0 1678462 5630123 2931727 1457106 3776501 1687898 0 0 0 1299105 2335293 1673036 2485730 0 0 2331720 0 2332770 0 1555006 0 1344382 0 2008454 0 1383177 0 2011987 1618361 0 4812781 6972624 2444767 0 0 0 1218286 3682967 +AAANATGYDVVLGTSS(Ser->Gly)K MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03061 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3806621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4531401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1183467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1013364 0 0 0 1866485 0 0 0 0 0 0 0 3267315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1986948 0 2690352 0 0 0 0 0 0 2273118 0 0 0 0 0 584750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1522303 0 0 0 0 0 0 0 0 0 0 0 0 1307112 0 0 0 0 0 0 0 0 3373515 +AAANATGYDVVLGTSS(Ser->Gly)KK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03061 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANATGYDVVLGTSSK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03061 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 313507 656960 405350 211321 342257 545151 360441 300559 0 0 486200 399946 541869 113318 389177 354709 379306 388189 594554 202524 0 145194 292671 346375 317607 265846 177376 752557 448491 0 284969 385571 290765 289205 0 201482 399905 331945 455164 576565 332041 675573 348333 275839 619227 400099 0 0 665863 77133 429000 284682 389117 429636 0 388078 0 459276 0 180100 188942 533783 270816 555671 483733 343948 449186 0 858575 329178 255648 446520 0 616139 373080 332730 695950 6443044 1306328 1143364 2936970 1544944 258642 840497 0 0 1743849 2820887 1492451 779632 685282 1599324 1069600 3400345 985655 545648 0 1706295 2748282 1653460 883716 900955 0 2580595 496420 0 2797732 5338637 1319239 524831 0 540343 276031 1291795 387886 335084 596481 301812 460529 312566 436959 323620 0 0 340873 451159 342803 394449 307316 380627 454614 0 285582 502897 0 0 0 462505 232382 338352 273591 267879 200682 0 569564 395653 624022 310088 0 0 218971 0 6313634 0 18761703 7615871 19830379 8279260 5983683 9222815 0 0 10313009 7163383 18763620 5689239 6076925 12043958 7612569 16399816 5984604 6799097 0 8107167 14902693 11141097 5877024 7337344 6156024 13796345 7394434 0 27921625 0 14922816 8447172 0 6102920 7710757 23345111 +AAANATGYDVVLGTSSKK MGYG000001338_03061;MGYG000001338_03083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 0.5 2|Bacteria 0.5 S 1.0 peptidase inhibitor activity 0.5 - 1.0 - 1.0 3.4.24.40 0.5 ko:K01406 0.5 ko01503,map01503 0.5 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 0.5 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03061 0.5 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 0.5 0.5 0.5 0.5 Cationic antimicrobial peptide (CAMP) resistance 0.5 K01406:prtC; serralysin [EC:3.4.24.40] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241941 221524 302920 322633 0 105937 221432 202200 0 0 0 0 0 0 177496 344331 0 233391 0 107795 0 0 332731 0 0 0 0 102351 0 223919 0 0 199842 175303 0 0 0 0 129561 0 2353197 401987 384775 773031 604451 491872 424144 0 0 560378 782720 444163 450068 391185 576947 352683 1234538 409360 441597 0 508105 1135542 632598 286331 318941 494705 1045951 388521 0 1213583 2375379 561498 471477 0 368736 215093 425890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3847003 18010849 9671636 3877653 9857247 4107963 3473744 3188647 0 0 5123821 4134749 6918508 2322371 3276422 6240788 2989575 6014247 2955224 3179469 0 3285171 5604805 5061296 3060959 2881899 2656322 5900459 3555096 0 12923642 17178615 6489082 3532620 0 2665455 3215020 10474594 +AAANE(Cation_Ca[II])SFGYNEDEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 567576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 735964 0 0 0 0 0 0 0 0 0 0 552466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1012269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANE(Cation_Fe[II])SFGYNEDEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446089 0 0 0 0 0 224030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANE(Cation_Na)SFGYNEDEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1366972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGY(Amino)NTDEIVSSDIVGMR MGYG000000223_00996 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,3VP0T@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_00996 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 647777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGYN(Deamidated)EDEIVSSDIVGM(Oxidation)R MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 562342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585755 0 0 0 0 0 0 835073 0 0 0 0 803266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1356748 0 0 0 0 0 0 1209110 0 0 0 0 1961970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1005703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGYN(Deamidated)EDEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 752870 0 0 0 0 0 398985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1446836 0 0 0 0 0 512769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3572436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGYN(Deamidated)TDEIVSSDVIGM(Oxidation)R MGYG000003001_00320;MGYG000002052_00078 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003001_00320 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGYNE(Cation_Ca[II])DEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 418533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221512 0 0 0 0 0 0 0 0 0 0 0 0 0 127139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588953 0 0 0 0 0 0 760760 0 0 0 0 0 0 719806 0 0 0 0 0 0 0 0 691601 0 0 0 0 0 0 0 0 0 0 748706 0 0 0 0 0 0 0 0 1523579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 907287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGYNE(Cation_Fe[II])DEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 384856 0 454156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 893848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGYNE(Cation_K)DEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 123835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGYNE(Cation_Na)DEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 1807701 0 0 0 0 0 0 0 0 0 1301846 1249359 0 0 0 0 284422 0 0 0 0 0 1131793 0 0 0 0 0 0 739339 1756349 0 0 1576283 0 0 0 0 0 791845 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1539158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2167541 0 0 0 0 0 0 0 0 0 0 0 0 920064 0 0 0 0 0 0 0 0 3125012 0 0 0 0 0 0 0 0 0 0 1895510 0 0 0 0 0 0 564779 0 3713904 3383433 0 0 0 0 0 0 695870 1264298 0 1431908 0 0 0 0 0 0 1143189 0 2186671 0 0 0 0 1611803 0 0 2722657 0 1842016 2631385 0 0 2002644 0 0 0 0 0 0 0 0 6441692 3198939 0 0 0 0 3088664 0 4076251 0 0 4906726 0 0 +AAANESFGYNED(Cation_Ca[II])EIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 517992 0 402134 546003 0 383266 445428 594990 0 601756 552123 692209 358526 370705 373715 0 544411 192008 381081 347588 0 327085 235878 179306 0 358902 470656 334769 0 743718 260769 0 203131 555234 486658 377966 517286 181960 147513 0 148748 190653 0 135262 363353 154588 110338 0 176868 131221 114432 106134 169218 0 113406 826982 57216 206109 0 0 254537 238967 0 101687 170800 666624 0 149955 129581 0 154093 167874 222703 184058 140739 113293 658982 0 730192 537066 0 474824 501508 0 392560 481723 661342 732005 614097 587529 719210 0 543641 221872 0 0 0 544965 496499 332962 0 621515 0 719516 0 682880 402414 0 1222045 0 693766 398971 585478 1018983 1347560 0 384873 1581304 0 532564 825545 1638904 1563001 731254 709971 745642 512728 1291138 1342586 0 1012851 113448 1166601 1200214 0 454485 270268 330546 0 1439199 1335467 252682 0 1000547 557881 0 367374 582451 1153904 1074333 1376505 394787 816608 0 827527 0 0 699974 586934 432301 880039 0 1025326 617876 268123 1306101 1158830 0 0 81305 0 767574 0 1371896 69029 901156 0 611455 1204589 257896 0 762890 625793 0 1029887 0 15270 541272 6485 0 +AAANESFGYNED(Cation_Fe[II])EIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 515520 0 214117 0 0 376869 464713 667711 519845 625966 573369 665170 0 412134 374949 211056 345880 141694 536363 394271 426799 337067 209112 175312 460592 208971 0 197947 0 656957 0 242566 274064 563961 490457 332849 584351 200334 150379 0 112062 0 0 85389 227270 188812 57683 0 201504 69325 0 0 148222 227451 498133 724885 56847 0 0 105157 214815 0 78192 112514 0 622371 0 0 0 106058 52182 109572 273924 225783 176783 114257 552687 0 513332 0 0 462590 330063 0 215061 387149 444678 545479 0 438246 566238 606158 402547 0 250710 454255 401328 463433 366486 382017 515195 560214 0 370678 0 306896 0 299862 920343 0 698651 327956 579898 0 0 0 278513 0 0 435208 846934 1346016 0 616885 581610 687107 0 1113400 0 789873 870707 173941 0 1057112 1028418 264946 95026 201769 1424798 1203225 0 125279 0 0 0 406879 260855 508452 913689 919151 0 352872 0 0 727779 0 0 571769 0 408169 583346 0 772801 474692 0 604219 0 524231 890054 0 704663 479458 577414 612393 0 548866 819611 413242 0 151394 0 444997 0 0 1331103 6611 0 1234153 7758 0 +AAANESFGYNED(Cation_Na)EIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 1646381 1127075 887051 0 1181688 1008680 1450578 1851117 1438372 1930811 1894837 2070917 1252559 0 0 1012324 1481908 604410 1630347 1195028 1372407 1054014 609977 703807 1545414 0 1556570 965752 0 2028420 709935 715257 0 0 1628383 1293976 0 666117 679682 551949 509166 681824 0 209778 919157 469296 306985 426671 892882 483850 724346 370242 454997 533837 446207 2756101 498317 908057 541654 256286 0 551910 619915 575328 656201 0 0 614861 512064 605496 501590 625293 652710 707985 467682 695116 2233506 0 1941338 1346319 1386397 1300931 1349043 2062460 1095366 1712273 1786595 2667207 1743986 1623716 2069205 0 1615408 768318 2003125 1931932 1456003 1618934 1311721 944081 1938918 2550374 2130899 1630557 0 1819444 1233706 1420902 3599608 2143763 2350335 1177170 2051367 0 4506610 1418844 1423303 4843564 2300050 1834233 2445537 4686385 4219695 2541504 0 2510138 1497839 4504074 4276860 2496490 3205579 0 3792469 0 0 881475 904643 1627201 4363823 3630263 3929869 0 0 3330153 0 1509457 946795 1930278 3508222 3177744 0 0 2707395 0 2341440 136938 1686545 1879221 0 1326329 2460626 0 3976602 0 0 5607933 3873385 0 3031878 298625 2900438 2586515 2051107 6157346 632733 4497083 0 0 5352793 1182091 0 2133750 0 0 0 77535 3608593 0 2941562 1504766 +AAANESFGYNEDE(Cation_Na)IVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGYNEDEIVSSDIVGM(Carbamidomethyl)R MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 654811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 972178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1994568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGYNEDEIVSSDIVGM(Oxidation)R MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 851054 593403 627224 1223926 890968 1273162 760079 780181 1194670 959767 1433577 1545788 0 384320 1317992 0 2139997 1076027 1252607 914320 1001702 1097422 399514 491395 1420177 910106 844439 547625 604658 1075971 377763 544836 409835 1007635 815916 687766 942784 364769 309980 307344 175250 340397 592210 0 272082 0 606853 0 608244 190478 0 212184 295423 321647 0 1685148 0 315112 269898 0 828834 214375 0 177216 326403 1128192 289394 0 417493 0 218270 300101 180436 208916 259775 514577 1856689 2005594 2038806 1923445 1017282 926137 1151194 1582196 1162264 1484970 1463598 1857058 1253111 1278860 1396366 1404965 1179129 630679 1178074 1387911 1018353 942025 1111003 950756 1381385 1905819 1215516 1184858 619412 1311738 984511 1144230 2523815 1341451 1349932 919110 1205756 2180818 2999993 1094156 870082 3671393 1891427 1250938 1723844 3824548 2978936 1709444 1610856 2052779 1128841 4370698 4091260 1625897 2497931 584973 3036379 3288166 3467585 666530 764099 736133 3747528 3874389 3704834 1040081 852736 3517709 1279009 1357895 1067681 1940655 4485748 2545786 4253833 936746 1840616 1746198 2634190 0 1582438 1877970 1753797 1204504 1559745 2441144 1867973 1437345 1306579 2563582 2906370 1215867 1776092 196871 2206494 1497401 1635632 2191550 386180 2250976 2672628 1723780 2734260 590953 516563 1152246 1086017 450226 3140618 2320410 2081330 2209852 2662487 1842715 +AAANESFGYNEDEIVSSDIVGMR MGYG000003694_01737;MGYG000001186_01925;MGYG000003012_02911;MGYG000000271_03250;MGYG000003821_01266;MGYG000004271_00554;MGYG000000404_00344;MGYG000000262_01195;MGYG000002517_01026;MGYG000001652_01009;MGYG000002492_01379;MGYG000000489_00503;MGYG000000806_01930;MGYG000000077_00219 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.7142857142857143 186801|Clostridia 1.0 G 0.7142857142857143 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.7142857142857143 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01737 0.07142857142857142 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 6060616 4179273 3570837 0 4596647 3692943 5465877 6601781 6217972 7763922 6626410 7350743 4561383 4144766 5354184 3940032 6189460 2080276 6058984 4224800 4475647 4029159 2117067 2351856 6927075 4516445 5868113 3489624 3624062 8010157 2510167 2919008 2370015 6263195 4818612 4768175 5107689 2010542 2309149 1629517 1627489 2416922 3383650 1290899 3682763 1962225 1517767 0 2616608 1525662 2135337 1431351 1864040 1995674 1437190 10167390 1464690 3536506 2277976 1227768 5879509 2346531 2433367 2123349 2173760 8193262 2397680 1654917 2157218 1993009 1326700 1953423 2173779 2160428 1708040 2392436 7510194 5869136 7848368 4502897 4280795 4794117 4338899 7813478 4018432 5538228 6853924 9281004 6891502 5226289 7834301 9655099 5455607 2434792 7449924 6799288 5693741 6115467 4821119 3294712 6939973 7824180 8275446 6525485 3585308 5819248 4875964 5359150 12783545 8602971 8331364 3926951 6708831 11879680 16464784 4598751 4146547 16979023 7500569 4965726 9286928 16939558 15626352 8114204 6883780 8207485 4745350 14527995 17718872 8782051 12227004 1730012 14404792 11986237 9383481 3058026 1738225 11485204 14029043 14079946 14375671 2720329 4052257 11418157 4312884 5509243 3661532 6257361 12644958 11516713 15630822 3984718 8830516 7153307 7663196 2375644 4865847 6913256 5404403 3915821 8662986 10363724 38610997 6259644 23088141 71087349 18055025 7693260 13091141 1206955 14183784 11901241 14414058 61300464 3485177 48698499 64119331 19724900 83231950 9989554 15685621 12427272 30393249 10504003 57338722 81205758 151960711 93723338 120097668 87116102 +AAANESFGYNEDEIVSSDVIGIK MGYG000001421_02311 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__Dielma|s__Dielma fastidiosa|m__MGYG000001421 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,268FY@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001421_02311 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1019339 0 0 0 0 0 0 0 0 377390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 985782 0 0 0 0 0 0 0 0 1741055 0 0 0 0 0 0 0 0 +AAANESFGYNTD(Cation_Na)EIVSSDIVGMR MGYG000000223_00996 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,3VP0T@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_00996 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 866818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 982088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGYNTDEIVSSDIVGMR MGYG000000223_00996 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,3VP0T@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_00996 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 187765 0 0 0 170011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246662 266310 0 227286 0 0 0 0 117155 198142 0 237196 0 0 0 0 0 0 0 608360 0 0 0 373146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3050156 497919 0 621672 0 0 0 0 3866853 3745292 0 491826 0 0 0 0 0 0 0 247081 0 0 0 440118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1838791 724115 0 855626 0 0 0 0 1514680 2791848 0 3079629 0 0 0 0 0 0 0 3688743 0 0 0 1042291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10296901 909686 0 92054 0 0 0 0 0 1302149 0 12110253 0 0 0 0 0 0 0 6815690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1074137 0 0 2844136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGYNTDEIVSSDVIGM(Oxidation)R MGYG000003001_00320;MGYG000002052_00078 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003001_00320 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESFGYNTDEIVSSDVIGMR MGYG000003001_00320;MGYG000002052_00078 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003001_00320 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 450182 0 0 0 0 0 0 0 0 0 821295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7104318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1388735 1702563 0 0 0 0 0 0 0 0 0 1510107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321461 0 +AAANESYGYN(Deamidated)EDQIVSSDIVGMR MGYG000001310_02090 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_02090 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESYGYNED(Asp->Asn)EIVSSDIVGMR MGYG000001439_00571 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Faecalimonas|s__Faecalimonas umbilicata|m__MGYG000001439 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001439_00571 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 986430 0 0 0 0 0 0 0 0 0 1047051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 201001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321863 0 0 0 0 0 0 0 0 0 1183313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESYGYNED(Cation_Na)QIVSSDIVGMR MGYG000001310_02090 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_02090 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 708826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESYGYNEDEIVSSDIVGM(Oxidation)R MGYG000001439_00571 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Faecalimonas|s__Faecalimonas umbilicata|m__MGYG000001439 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001439_00571 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 418179 0 0 0 0 956608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552559 0 0 0 0 0 0 0 0 0 399787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESYGYNEDEIVSSDIVGMR MGYG000001439_00571 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Faecalimonas|s__Faecalimonas umbilicata|m__MGYG000001439 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001439_00571 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363404 0 0 0 0 796079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 761152 0 0 0 0 552311 0 0 0 0 907165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403709 0 0 0 0 824581 0 0 0 0 801767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 455116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277290 0 0 0 0 352588 0 0 0 0 0 0 0 0 0 0 +AAANESYGYNEDQIVSSDIVGM(Oxidation)R MGYG000001310_02090 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_02090 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 352247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 202116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANESYGYNEDQIVSSDIVGMR MGYG000001310_02090 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_02090 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 2504204 2553254 0 0 0 0 0 0 2800461 0 0 0 0 0 0 0 0 1971021 0 966667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 452293 0 0 0 0 0 0 0 0 321690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 743352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 667447 0 548490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANFNNFQEK MGYG000002438_02937 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,22VYG@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Protein of unknown function (DUF1015) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1015 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02937 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 231149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 616337 0 0 913283 467520 1002853 0 764169 0 0 0 0 879004 0 802191 0 1123370 0 0 0 0 0 0 0 0 0 0 0 0 582016 0 612862 0 0 0 0 0 0 411834 0 0 0 281667 420096 0 433221 0 0 0 0 357839 0 493103 0 726328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376518 0 0 0 0 0 0 334113 0 0 0 303732 612543 0 774930 0 0 0 0 286729 0 146189 0 1307787 0 0 0 0 0 0 0 0 0 0 0 0 556914 0 435641 0 0 0 0 0 0 2082915 0 0 2112695 1451670 1629312 0 2199251 0 0 0 0 1769360 0 2040262 0 2917222 0 0 0 0 0 0 0 0 0 0 0 0 1826948 0 1361638 0 0 +AAANNPELAAFIDEC(Carbamidomethyl)R MGYG000002494_00657 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0495@1|root,COG0495@2|Bacteria,1MV47@1224|Proteobacteria,1RP14@1236|Gammaproteobacteria,3WW28@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Leucyl-tRNA synthetase, Domain 2 1.0 leuS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.4 1.0 ko:K01869 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03657 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 iECOK1_1307.ECOK1_0652,iECS88_1305.ECS88_0684,iNRG857_1313.NRG857_02925,iPC815.YPO2610 1.0 Anticodon_1,tRNA-synt_1,tRNA-synt_1_2,tRNA-synt_1g 1.0 - 1.0 - 1.0 - 1.0 GH13_26 1.0 MGYG000002494_00657 1.0 leucine--tRNA ligase. leucyl-tRNA synthetase. - ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01869:LARS, leuS; leucyl-tRNA synthetase [EC:6.1.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1380620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAANYLDIPLYR MGYG000003363_02712;MGYG000002033_02968;MGYG000001306_00798;MGYG000002478_03016;MGYG000002438_02238;MGYG000002478_00851;MGYG000000243_01149;MGYG000003367_02246;MGYG000000355_00667;MGYG000002455_01185;MGYG000002438_01170 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 0.7272727272727273 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000003363_02712 0.09090909090909091 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 1581555 0 1709943 0 0 1152361 0 0 0 0 0 0 1324889 1267473 0 0 0 1208740 1582281 1325781 0 0 2079893 1579576 0 1304390 0 1867357 1504863 0 0 1073491 0 0 1046823 0 0 0 2847018 3067502 0 4239633 0 0 2800480 0 0 0 0 0 3863385 3611032 0 0 0 5207921 0 0 0 0 7647929 3068264 3591883 0 0 6574487 3835200 0 3245480 0 0 0 0 0 0 0 0 2236695 2849726 0 0 0 2332814 0 2386304 0 0 0 0 0 1760843 2306803 0 5808344 1863777 1660435 0 2067195 5797651 2695614 0 1919845 0 5307481 2467706 0 0 1980815 0 0 2122845 0 0 0 0 283606 0 203022 0 286654 0 0 0 0 0 0 387410 0 471673 283627 0 0 0 391205 0 0 0 0 452393 0 917221 0 0 0 645084 297535 393337 0 357792 0 905732 0 0 0 0 0 0 0 1236377 0 0 843954 1299775 0 0 0 0 1783115 0 4761989 1440430 0 0 1302960 4239934 0 0 0 1676829 3598689 0 0 0 0 1041649 0 1965041 1825575 0 1716292 +AAANYLDLPLYR MGYG000001306_00798;MGYG000003312_00286;MGYG000002438_02238;MGYG000002478_00851;MGYG000001461_01176;MGYG000002455_01185;MGYG000001641_01230;MGYG000003363_02712;MGYG000003351_05187;MGYG000002033_02968;MGYG000003701_04731;MGYG000002478_03016;MGYG000000243_01149;MGYG000003367_02246;MGYG000000355_00667;MGYG000002438_01170;MGYG000000098_00210;MGYG000000013_00888 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 0.7777777777777778 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000001306_00798 0.05555555555555555 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 1599105 0 1501806 1279350 0 1880788 1346755 1493571 1442729 1930038 1592373 692831 1014761 1185084 1315237 1387472 0 0 0 1312030 1219760 0 1220190 1283965 1100273 1466757 0 2079134 1211866 1681601 0 1543139 1488362 0 1682885 1307039 1466144 0 912201 2901308 1559327 4183900 3485764 0 4073946 3487693 3612620 3664315 3982480 0 1329988 4625418 4626753 3203528 0 3622610 3523640 4982339 3735403 0 0 0 5139272 3279910 0 0 3581302 877009 4838523 3343258 3279957 3192906 2959333 3151324 2762582 1724915 0 0 1979131 3330489 2966908 0 1700148 0 1803799 2423734 3069656 1805490 2113554 0 869235 1606411 0 0 0 1710198 0 0 0 1808598 0 1882325 0 0 2172017 3167951 843113 1990551 1639115 0 2668834 2077252 2606328 535225 834637 217425 612677 215175 662001 321063 521622 380276 353991 464844 927808 717685 311611 734289 691031 240464 0 477496 671637 3497980 818941 0 519109 967891 613566 565816 0 232884 1179960 0 1130808 667625 706702 855799 536158 522756 475684 1392713 1033053 1228144 1720325 2515205 1794472 0 2053607 1819951 809238 0 1382104 1701750 1405062 1436859 0 1723994 0 0 2006946 3251459 1663347 0 1713364 1595903 2117680 333551 0 1913342 3886349 1833368 1374491 0 1843363 0 798110 2012721 0 +AAAPAAAAPK MGYG000002492_01473 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01473 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 791481 0 0 0 0 297380 0 0 0 0 493787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4162099 0 0 0 0 3563315 0 0 0 0 3607277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1305920 0 0 0 0 1674744 0 0 0 0 2397407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428334 0 0 0 0 0 0 0 0 0 930634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76443 0 0 0 0 204430 0 0 0 0 61539 0 0 0 0 0 0 0 0 0 0 +AAAPAAAPAAKPAAAAGAGSVK MGYG000002517_01656 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01656 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920373 0 1086901 0 0 1097103 0 0 945916 1118856 1061545 0 0 0 0 0 939380 0 0 0 0 906399 0 1024867 0 1157964 0 0 0 0 658332 0 1129042 1003331 0 1641843 853113 904987 +AAAPAAEAPAAK MGYG000000179_03221 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24R6P@186801|Clostridia,220KI@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03221 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 132342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1047867 0 0 837012 468640 0 0 0 992760 0 587495 610231 847682 1170768 1290578 850849 0 0 794668 1148627 1101815 0 0 0 0 0 1633257 0 1164177 1075390 0 0 0 0 0 1609170 418150 0 0 0 218959 247596 411036 0 0 0 114960 543934 0 355417 183514 411263 572165 141544 0 0 0 199496 219932 342029 0 473570 0 484417 294621 0 0 290914 316264 0 0 0 0 518468 367098 556846 13290784 0 3672459 6333029 8670391 3867822 0 4053702 6133198 7515204 2862747 5721816 2748890 11658690 9438026 5575618 9761693 0 5616288 15386504 4413063 5961904 0 8412068 4037408 16510606 9708051 0 11699547 5567978 3395676 0 5159591 0 0 14128251 11212668 6818706 +AAAPAAGAGAVK MGYG000001338_01632;MGYG000000133_01634;MGYG000000171_00279;MGYG000000213_01127;MGYG000002298_00907;MGYG000000200_00817;MGYG000000806_02004;MGYG000003012_01442;MGYG000000212_00763 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01632 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1518500 2551479 2235815 885740 2959717 2974851 997537 1347308 1163457 1364702 2332104 1684614 2490739 1267206 1644407 2891237 954677 2901865 1894202 1291283 1723718 4663821 1874416 1938176 1588930 1153367 1075634 2137964 3364505 0 2459155 2158809 2063739 0 1415823 989603 1110722 2780262 379693 5437220 471683 590810 938445 467214 525878 668561 492189 373266 802079 285586 905737 398652 191488 184805 304457 2115436 460911 522159 310046 386913 1315677 695322 478362 494356 542032 2372441 2612280 0 4200447 1767082 493778 0 575789 672317 420915 0 548359 5783804 952832 266985 0 364025 303858 1468645 192474 640148 557009 750181 1063374 391963 855719 1070913 1356761 537070 792406 943479 361396 1002887 934120 0 984659 641287 645604 696020 1373740 0 1815859 3573075 1882139 0 798192 266924 435779 977104 301766 2435885 1694118 469424 1353785 556624 409125 582397 196673 678641 1373439 605332 1079786 503373 913068 1042863 807693 890984 310496 693704 0 1268020 115720 1477333 0 126483 236013 1555805 4639219 0 4185705 1743776 1371890 0 540036 338324 0 2335448 5691805 4621975 4086409 4987671 1262582 2589393 6714645 4752074 2981685 6385754 8283005 4251538 8678947 11093452 6869668 3793667 4939336 1093765 4671025 1525478 5260065 2866978 1576394 3670062 5543288 5526393 7260483 1638956 7012629 0 5417842 5304956 11804122 0 3920652 7534809 3348988 5253171 +AAAPAAGAGSVK MGYG000000142_00945 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_00945 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1048708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525443 0 1244682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2010017 0 835700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406850 0 457168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAAGGAAAAEEK MGYG000004769_00419;MGYG000004802_00517 domain d__Bacteria 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4H4X8@909932|Negativicutes 0.5 909932|Negativicutes 0.5 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_00419 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298232 0 0 0 0 0 0 0 0 0 0 0 722659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 666006 0 0 271782 0 0 0 0 0 0 0 202660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241399 0 0 0 0 0 0 0 168590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 235915 0 0 0 0 0 0 0 0 0 0 472015 0 0 0 0 0 0 0 0 0 0 0 698960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 915199 0 0 0 0 0 0 0 519526 +AAAPAAPAAAA(Ala->Pro)K MGYG000003899_00809 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539945|m__MGYG000003899 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003899_00809 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1187996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAAPAAAPK MGYG000000271_00470;MGYG000000249_01881 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 0.5 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 0.5 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00470 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 482007 0 651830 0 0 0 0 0 0 0 660163 0 0 0 0 0 357669 0 0 406703 0 0 0 0 0 538315 0 0 0 354297 0 0 633201 0 0 0 822821 518016 1361204 0 2547176 0 0 0 0 1126086 0 0 1238028 0 0 0 0 0 5686977 0 0 1006344 0 0 0 0 0 0 0 0 0 779856 0 0 2568217 0 0 0 1137524 2854908 681793 0 1444363 0 0 0 0 421357 0 0 289210 0 0 0 0 0 385553 0 0 230788 0 0 0 0 0 313960 0 0 0 307434 0 0 1157132 0 0 0 523116 1259913 240578 0 941785 0 0 0 0 363500 0 0 276513 0 0 0 0 0 405286 0 0 0 0 0 0 0 0 0 0 0 0 324168 0 0 0 0 0 0 0 923295 290263 0 0 0 0 0 0 154631 0 0 0 0 0 0 0 0 821822 0 0 454394 0 0 0 0 0 522985 0 0 0 768832 0 0 166409 0 0 0 611681 278206 +AAAPAAPAAPKAA MGYG000003166_01306 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539885|m__MGYG000003166 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_01306 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2107619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAAPK MGYG000000133_01634;MGYG000002042_00590 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 0.5 186801|Clostridia 1.0 I 0.5 Biotin-requiring enzyme 0.5 gcdC 0.5 - 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 0.5 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 0.5 - 1.0 - 1.0 - 1.0 - 0.5 MGYG000000133_01634 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 0.5 none 1.0 141596 179211 377953 260101 0 159297 172824 235176 222822 0 0 288542 201110 0 503769 282975 350405 0 0 0 0 0 0 333356 268488 272002 272583 0 341865 0 0 0 349744 0 0 0 182252 376760 144814 166553 103182 1353668 0 190092 0 0 116055 0 0 1446231 65950 0 0 176158 143342 0 0 0 67950 210639 0 438078 0 0 196708 0 65491 0 335309 0 69354 0 54090 107173 187785 216096 106486 0 212487 0 0 0 0 0 0 0 0 0 0 0 165072 0 125421 0 0 0 0 0 0 0 134541 297653 230212 0 154791 0 0 0 290889 0 0 0 0 144246 126783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143210 0 0 0 0 119612 0 0 0 177199 0 127638 96068 10989742 8216858 11519940 14455000 0 4481086 15915243 6464805 6935695 16440276 20201070 14532252 10567505 22439655 9984082 8363707 7058082 0 12681243 0 13430128 7156767 0 0 13506401 10709911 14276408 0 15078055 0 12319391 11063971 22419602 0 11635306 19029039 7752232 0 +AAAPAAPVAPK MGYG000001300_00242 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00242 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 252300 0 0 0 0 0 0 0 0 0 0 0 0 276354 0 0 0 0 486272 263298 0 0 0 107509 151664 149988 0 0 0 0 0 0 0 0 0 0 0 0 1861119 0 2086584 1461169 0 1631446 1900242 2341533 2563515 0 0 1669256 1099808 1678270 0 843260 2485163 0 2370597 1565922 1559776 1140742 0 911245 2006325 1405342 0 0 0 1536723 0 0 2449824 1718891 0 0 2142440 1665227 1211066 0 2136574 1352287 0 2384544 1870280 2461544 152221 0 0 1280546 1571660 1532074 0 270666 1364244 0 1006194 1606335 1676997 1328030 0 1738932 1619812 1431073 0 0 0 1538146 0 0 1794157 1495870 0 0 1246912 1816007 2532828 0 5198705 2544181 0 5296084 4946403 1358247 3496680 0 0 3711964 3510913 2962332 0 3490437 3645842 0 4284936 2500336 2307339 5895636 0 5331883 1986992 3039277 0 0 0 3347064 0 0 5059715 3239561 0 0 2362699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAEEAAAGPSEVTVTLTDVGGTK MGYG000000223_01551 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,36IQP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_01551 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 314148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391416 0 563922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140199 0 0 0 0 0 0 0 0 0 0 0 0 1524896 0 0 0 0 0 0 0 0 0 979654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369922 0 0 0 0 0 0 0 0 0 0 0 0 798143 0 1563291 0 0 0 0 0 0 0 1040489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609348 0 0 0 0 0 0 0 0 0 0 0 0 153844 0 1693815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAGAAGAVTVK MGYG000000022_01358 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01358 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 455157 0 0 0 0 0 0 0 0 0 155890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2141061 0 0 0 0 2130800 0 0 0 0 1909461 0 0 0 0 0 0 0 0 0 0 +AAAPAGAGSIKVEAGAAGK MGYG000002492_01473 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01473 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270253 0 0 0 0 0 0 0 0 0 179701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293563 0 0 0 0 269807 0 0 1581117 0 0 0 0 0 0 0 0 0 618821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1415205 0 0 0 0 1126214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAGAQGAVK MGYG000000187_00854 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,25WYH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000187_00854 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756338 0 0 5069544 0 0 0 0 4118658 0 0 0 0 4073517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466394 0 0 0 0 551278 0 0 0 0 504065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559742 0 0 0 0 0 0 0 0 0 613537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1054369 0 0 0 0 392590 0 0 0 0 1498405 0 0 0 0 0 0 0 0 0 0 +AAAPAGGAGNVK MGYG000000271_00470 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00470 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 229255 0 0 0 0 0 0 0 0 771965 0 0 0 0 0 745891 280503 0 354344 0 0 0 0 564494 1167739 0 0 0 849950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367031 0 0 0 0 0 0 0 0 741594 0 0 0 0 0 574953 788329 0 762338 0 0 0 0 836546 400756 0 0 0 796876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280266 0 0 0 0 0 0 0 0 +AAAPAGGAGNVKIEAGAAGK MGYG000000271_00470 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00470 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAKPMGPNDYMVIGLAR MGYG000002494_03382 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1RHH7@1224|Proteobacteria,1RNAT@1236|Gammaproteobacteria,3WY36@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 PTS system sorbose subfamily IIB component 1.0 manX 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0008645,GO:0008982,GO:0009401,GO:0009987,GO:0015144,GO:0015145,GO:0015149,GO:0015578,GO:0015749,GO:0015761,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0022870,GO:0031224,GO:0031226,GO:0034219,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046323,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098657,GO:0098704,GO:0098708,GO:0098739,GO:1904659 1.0 2.7.1.191 1.0 ko:K02793,ko:K02794 1.0 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 1.0 M00276 1.0 R02630 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.6.1 1.0 - 1.0 iAPECO1_1312.APECO1_874,iECOK1_1307.ECOK1_1934,iECS88_1305.ECS88_1869,iPC815.YPO1758,iUMN146_1321.UM146_08085,iUTI89_1310.UTI89_C2014 1.0 EIIA-man,PTSIIB_sorb 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03382 1.0 protein-N(pi)-phosphohistidine--D-mannose phosphotransferase. mannose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-mannose(out) + N(pros)-phospho-L-histidyl-[protein] = D-mannose 6-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Phosphotransferase system (PTS) 1.0 K02793:manXa; mannose PTS system EIIA component [EC:2.7.1.191]|K02794:manX; mannose PTS system EIIAB component [EC:2.7.1.191] 1.0 none 1.0 0 0 0 160893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480128 0 0 0 0 212050 0 168744 0 0 0 126237 0 0 0 0 0 0 0 0 1060129 1348250 1187859 1502007 0 3323913 1728591 0 823030 2343473 0 0 0 1499761 0 0 2063732 0 2097359 1584765 0 3941197 0 2808386 1642326 1398334 1240018 0 2555717 2221526 0 0 1314397 0 0 1178940 994789 757514 252824 368539 682115 0 0 973463 0 0 0 0 0 0 0 0 0 0 0 0 640288 386451 0 170640 0 160029 0 0 0 0 0 0 0 0 241676 0 0 246030 0 777623 0 481271 0 889183 0 0 0 0 0 646569 0 0 0 810282 0 0 411633 0 600526 347156 0 610472 0 510303 791603 1073608 468742 0 315543 0 0 0 367547 0 0 0 479165 479380 0 0 0 501953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124769 0 0 0 0 0 +AAAPAPAAAPAAAPAAAPK MGYG000004276_00434 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4|s__ER4 sp900550165|m__MGYG000004276 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,2N7T7@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-lipoyl like 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004276_00434 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572254 0 0 0 0 723062 0 0 0 507450 703896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAPAAAPK MGYG000000076_00252;MGYG000000245_00298 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 PFAM biotin lipoyl attachment domain-containing protein 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000076_00252 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3429633 0 0 0 0 0 0 0 0 0 0 1521067 0 0 0 0 0 0 0 0 0 0 0 0 3266323 2085717 0 0 0 2295236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAPAAK MGYG000002506_04250;MGYG000004769_01105;MGYG000002535_03464;MGYG000004769_00268 domain d__Bacteria 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 0.5 1236|Gammaproteobacteria 0.5 I 0.5 glutaconyl-CoA decarboxylase subunit gamma 0.5 gcdC 0.5 - 0.5 4.1.1.70 0.5 ko:K01615 0.5 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 0.5 M00307 0.5 R03028 0.5 RC00832 0.5 br01601,ko00000,ko00001,ko00002,ko01000 0.5 - 0.5 - 1.0 - 0.5 Biotin_lipoyl 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04250 0.25 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 0.5 0.5 0.5 0.5 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 0.5 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 0.5 none 1.0 0 0 278478 745506 357816 402853 0 469405 700922 0 517185 416070 418328 309164 0 589738 551107 0 0 3627625 574102 692659 0 414163 0 0 0 0 367885 0 0 447277 377602 0 0 591644 0 468199 0 0 442943 594674 384679 479818 0 753882 376170 0 720219 684773 224725 442628 0 297606 353849 0 0 365314 313647 444010 0 436180 0 0 0 0 421834 358568 0 377449 253869 0 0 319025 0 333401 0 0 170302 85482 159188 143636 0 223777 171864 0 188285 131986 199456 239133 0 159874 0 0 0 186246 347035 154803 0 356846 0 0 0 0 140162 0 0 159761 133624 0 0 210340 0 0 0 0 94655 86594 120636 155893 0 181671 149775 0 314183 68244 228109 156138 0 139182 58309 0 0 110724 140776 156017 0 241860 0 0 0 0 43573 2000146 0 236742 57873 0 0 121048 0 147133 0 0 0 226048 0 0 0 0 260459 0 101543 0 0 168227 0 0 65185 0 0 252729 310893 0 0 86919 0 0 0 0 208047 362892 0 0 0 0 0 0 0 94918 +AAAPAPAAKPV MGYG000004769_01105;MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01105 0.5 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2235119 0 0 0 0 0 0 0 0 0 0 0 0 1331337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1580894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5878558 0 0 0 0 0 0 0 0 0 0 0 0 3248252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7098403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAPAAKPVAAGAATISAPM(Oxidation)PGK MGYG000004769_01105 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01105 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3479748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAPAAKPVAAGSATISAPM(Oxidation)PGK MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_00268 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 607738 575858 428449 577692 0 0 541866 813859 0 768154 632967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603590 0 650491 0 0 0 0 601969 0 517790 378555 0 487585 0 0 442599 346441 0 515231 133108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 523502 0 317007 0 0 0 0 188846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAPAAKPVAAGSATISAPMPGK MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_00268 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5703713 7308503 7338217 6149340 6787096 6129564 4982690 8538436 5172738 6646002 7573580 6570334 4140413 5792872 5348378 6158311 6058979 786541 5753852 5336094 5381594 5668657 868718 5259945 5117779 5554442 5434615 699053 6034610 5563906 6439810 7383243 7198068 6325678 7578055 6005760 5243645 5591521 2915629 2541995 3052522 2262579 3758034 4026154 3474528 3746169 2882764 2318494 4073519 3440690 2866970 2530282 2681342 2796942 1770978 1454176 2785765 2782735 2565348 2725139 1536320 0 2747390 2761173 2766445 1115868 2222151 2802609 4280021 2791825 2495480 3289325 4262076 3620147 2689804 2676511 0 0 0 0 0 0 0 254313 0 0 0 0 0 0 0 221603 0 0 111554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPAPAPAPAAPAPAAAPAGAGEVVEAPMPGK MGYG000004158_00688 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister invisus|m__MGYG000004158 1.0 COG0511@1|root,COG0511@2|Bacteria,1VW7S@1239|Firmicutes,4H9EU@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Biotin-requiring enzyme 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 CBM50 1.0 - 1.0 MGYG000004158_00688 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 636039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPNQPK MGYG000002395_00968 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium adolescentis|m__MGYG000002395 1.0 COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Belongs to the transketolase family 1.0 tkt 1.0 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA,Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002395_00968 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1042278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2686650 0 2056971 0 0 0 0 0 0 619504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPSGASTGSR MGYG000002506_02347 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,3XNNK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 iPC815.YPO3376 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000002506_02347 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 67629 0 137194 0 0 0 0 0 0 0 0 0 299707 0 0 0 0 355886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 148507 0 0 0 0 198006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94054 0 0 0 0 0 0 0 800376 0 327977 0 0 0 0 0 0 0 0 0 318649 0 0 0 0 438819 0 0 0 0 0 0 0 0 0 0 0 0 675619 0 0 0 0 594618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPVAAAPA(Ala->Lys) MGYG000004804_00337 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900759415|m__MGYG000004804 1.0 COG0511@1|root,COG0511@2|Bacteria,1VW7S@1239|Firmicutes,4H9EU@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Biotin-requiring enzyme 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 CBM50 1.0 - 1.0 MGYG000004804_00337 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120240 0 0 0 0 115556 0 0 0 0 221301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 981517 0 0 0 0 4806765 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPVAAAPK MGYG000000142_00945 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_00945 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3074009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPVAAAPVAAAPAAAPK MGYG000003891_01453 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_01453 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 545447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1298786 0 0 0 0 1849039 0 0 446874 0 961901 0 0 0 0 0 0 0 0 433428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAPVAAGATTVSAPMPGK MGYG000001365_01216 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A|s__Phascolarctobacterium_A succinatutens|m__MGYG000001365 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001365_01216 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 85658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191359 0 0 0 0 0 164863 205315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736020 0 1009107 949521 888620 1264989 717318 1507665 864442 647719 848708 875117 910070 0 758556 0 642422 2525608 1050866 814251 0 1000793 2413916 1739021 0 856279 0 1926660 835477 997614 1035424 1381813 1195963 1003194 1524395 0 945283 1067227 +AAAPVAPTADPVIPK MGYG000000212_01006 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3XYZP@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01006 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2725912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQAAIANK MGYG000000231_00504;MGYG000000154_00436;MGYG000002517_01243;MGYG000000245_03386;MGYG000001698_00702 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000231_00504 0.2 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1038590 1181669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1337465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQAAIKNPR MGYG000002274_02693;MGYG000001647_00185;MGYG000004866_01031;MGYG000001300_02837;MGYG000002040_00906 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.8 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002274_02693 0.2 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQAALNNK MGYG000000193_00368;MGYG000000198_00250 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,268N0@186813|unclassified Clostridiales 0.5 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000193_00368 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 982671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQAALTEAISTISK MGYG000000171_02193;MGYG000004733_00324;MGYG000002298_03621 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3Y0DB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_02193 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02968:RP-S20, rpsT; small subunit ribosomal protein S20 1.0 none 1.0 0 0 537172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131098 0 0 0 0 526785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1056548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQELAEADRIK MGYG000002970_00028;MGYG000003266_00790 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CUC7@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 O 1.0 SPFH Band 7 PHB domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Band_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002970_00028 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQELAEADRIKR MGYG000002970_00028;MGYG000003266_00790 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,4CUC7@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 O 1.0 SPFH Band 7 PHB domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Band_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002970_00028 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQEQLATAK MGYG000002293_00897 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,2FNVT@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 N 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02557 1.0 ko02030,ko02040,map02030,map02040 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02000,ko02035 1.0 1.A.30.1 1.0 - 1.0 - 1.0 OmpA,ZapB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00897 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis|Flagellar assembly 1.0 K02557:motB; chemotaxis protein MotB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3134793 0 0 0 0 508998 0 0 0 0 3205290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQGNYDEAIANLSK MGYG000001415_00918 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG0457@1|root,COG0457@2|Bacteria,4PESY@976|Bacteroidetes,2G21B@200643|Bacteroidia,22UIH@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_00918 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 934494 0 0 0 575814 1028569 1467959 0 0 0 0 0 0 0 0 0 1241916 0 0 969667 0 735977 0 1408778 0 800293 0 0 0 0 0 0 0 0 0 1342122 1057016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492136 0 328334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 474049 0 0 0 0 0 0 0 0 383025 0 0 0 0 0 0 0 0 0 723202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQINLTPR MGYG000000003_00816 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG2911@1|root,COG2911@2|Bacteria,4NHAF@976|Bacteroidetes,2FMVP@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG10142 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Porin_2,SH3_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_00816 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 684040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQIVDTVK MGYG000000018_01784 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus|s__Coprococcus eutactus|m__MGYG000000018 1.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,36JJY@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Involved in the binding of tRNA to the ribosomes 1.0 rpsJ 1.0 - 1.0 - 1.0 ko:K02946 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000018_01784 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02946:RP-S10, MRPS10, rpsJ; small subunit ribosomal protein S10 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4675086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQLQQGLAATSDENLK MGYG000002494_04056 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2976@1|root,COG2976@2|Bacteria,1N117@1224|Proteobacteria,1S95P@1236|Gammaproteobacteria,3XMCB@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Tetratricopeptide repeat-like domain 1.0 yfgM 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_21,TPR_6,TPR_8,Tropomodulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04056 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746888 0 704193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQNLD(Cation_Na)GYNEAVAQVMSNNLSAAK MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00133 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579484 0 0 0 0 428968 0 0 231100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1848021 0 0 0 0 5007708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309612 0 0 0 0 254545 0 0 2869820 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQNLDGYNEAVAQVM(Oxidation)SNNLSAAK MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00133 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348861 241118 237358 447904 289633 882832 450811 0 0 0 0 0 0 0 0 0 299784 0 0 0 0 0 381379 328284 0 0 346066 222434 0 0 0 0 0 445668 422644 425977 0 0 0 279394 0 420496 0 323995 0 0 0 298275 0 0 0 453200 0 303200 0 0 0 0 0 422196 525012 0 0 0 430547 0 0 0 0 0 345818 354025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 344676 0 0 0 0 0 0 0 0 0 0 0 0 0 954175 0 780697 783003 1338734 1056878 806927 785451 1073733 868369 0 0 1070480 0 0 911582 799242 0 1234792 1757690 0 1314726 0 1113773 996021 796917 850548 0 0 989111 818443 0 627313 0 0 786894 1051902 593195 +AAAQNLDGYNEAVAQVMSN(Deamidated)NLSAAK MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00133 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 165175 0 0 0 0 0 0 197423 270989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304822 0 0 472280 259281 250279 0 612994 300417 485088 0 387569 0 0 332661 239035 356099 0 444664 445441 0 229941 0 357586 0 315041 0 0 0 396646 0 0 0 0 262687 0 358141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252615 0 0 0 268168 221949 0 0 0 0 0 0 266383 0 0 271683 282353 0 288628 0 0 0 300489 0 0 0 145490 0 0 0 0 0 0 273124 0 747435 0 0 880324 859150 890225 0 622435 695838 797562 0 583499 705634 0 809695 635209 746848 0 1167187 843872 0 405863 0 513950 0 886574 0 0 0 1147965 0 0 0 0 844528 0 806373 0 +AAAQNLDGYNEAVAQVMSNN(Deamidated)LSAAK MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00133 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 720584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQNLDGYNEAVAQVMSNNLSAAK MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00133 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 374063 339275 294225 0 531731 328467 0 440106 455857 443405 0 0 0 163592 414049 289811 233346 0 0 585535 606146 703430 0 629782 598792 671973 425150 0 344725 211523 166538 0 0 423387 0 1014474 346606 3332224 2217591 1529246 2013344 3713653 2756232 2211294 0 3025279 1909269 3250676 2194051 2525785 0 2878780 3545647 2358923 2179906 0 3155769 3942401 2824692 2135529 0 1512973 2552906 3141981 2467773 0 2281007 2292621 1470932 1802252 1927528 2995417 101072557 1971965 2277515 2209975 0 407520 0 0 127810522 224218 0 372727334 68435381 168903424 134781 0 0 0 185721 19928313 143222705 0 204992 222154 300107 273808 0 121481 71817040 43366441 641282 0 0 221674 0 252954103 0 123687048 29159053 0 75738086 105760497 34538106 1408389 0 24145828 2611242 25817012 0 4621862 3184588 0 71952971 2507187 0 6484574 5058090 25889500 12989370 0 0 2452818 385026458 14432587 0 173930 15517828 4995571 14033966 0 0 4257154 13186702 44146888 27682230 139510634 73658488 8438761 58584681 10113066 63373090 278362234 97867335 329851162 353498549 421777993 0 578828897 96468858 129842163 72760555 48383283 0 243382525 806283547 165133980 706367993 0 179128518 402064850 155622382 509472307 0 83556303 56770748 555458302 412436020 0 29098278 30624548 333389623 108233527 110474981 135483872 319575053 158539398 59653688 53315477 +AAAQPAQVNPC(Carbamidomethyl)IR MGYG000002223_01782;MGYG000001300_01680 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4,Fer4_10,Fer4_4,Fer4_7,Fer4_8,Fer4_9,MTHFR_C,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002223_01782 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03615:rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 724385 799357 1132147 908354 0 562111 379682 434858 554380 601250 649159 378592 0 349703 470762 882167 765933 0 772192 863553 0 959439 0 695451 557299 534800 551873 0 0 0 750099 613580 962743 786597 365367 513565 596354 954668 1605381 1420156 1418495 1714040 1252946 1364953 1888925 869692 1788816 326236 1204626 1509031 0 1674966 1415588 1053956 1727487 0 1931294 1653048 0 1231836 0 1650214 1974568 1546194 1609194 0 0 1320248 1717301 1355356 1644459 1718582 856800 1765824 1481294 1496606 0 244152 0 0 0 0 328616 391449 0 0 177633 0 0 0 0 257997 0 0 0 0 0 470300 0 0 0 248189 0 0 0 0 248686 358325 0 320393 269673 245588 0 0 798648 714916 1345716 816034 950461 1200647 978257 300775 1044324 556531 841506 1052032 0 322127 901023 978303 825737 0 1354033 857406 0 1202027 0 903371 936181 918094 824214 0 0 1039377 1328763 856936 1203671 761735 0 303510 908454 316136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQQELTR MGYG000003291_00352 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_M|m__MGYG000003291 1.0 COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 P 1.0 Belongs to the TelA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TelA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003291_00352 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 406405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 811093 0 0 0 0 0 0 0 0 0 0 0 0 936962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2278389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQSGAVGIR MGYG000004271_01794;MGYG000000084_00441 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia 0.5 186801|Clostridia 1.0 G 1.0 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) 1.0 nanE 1.0 - 1.0 5.1.3.9 1.0 ko:K01788 1.0 ko00520,map00520 1.0 - 1.0 R02087 1.0 RC00290 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 NanE,PTS_EIIA_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01794 0.5 N-acylglucosamine-6-phosphate 2-epimerase. N-acetylmannosamine-6-phosphate 2-epimerase. - an N-acyl-D-glucosamine 6-phosphate = an N-acyl-D-mannosamine 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 K01788:nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQSTC(Carbamidomethyl)PR MGYG000001636_00982;MGYG000002050_01032;MGYG000003266_01247 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0333@1|root,COG0333@2|Bacteria 1.0 2|Bacteria 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL32 family 1.0 rpmF 1.0 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 1.0 - 1.0 ko:K02911 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L32p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001636_00982 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02911:RP-L32, MRPL32, rpmF; large subunit ribosomal protein L32 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQT(Didehydro)ALLAATSEIDKAC(Carbamidomethyl)TK MGYG000000179_02162;MGYG000000198_04035 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,220RQ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02162 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02968:RP-S20, rpsT; small subunit ribosomal protein S20 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1117445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQTAFGAK MGYG000001658_01879 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01|s__SFFH01 sp900548125|m__MGYG000001658 1.0 COG1053@1|root,COG1053@2|Bacteria,1UK5H@1239|Firmicutes,250H0@186801|Clostridia,26CIB@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001658_01879 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1387248 0 0 0 0 538565 0 0 0 0 748056 0 0 0 0 0 484357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286011 0 0 0 0 143750 0 0 0 0 210801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1317094 0 0 0 0 1956839 0 0 0 0 1059018 1500729 0 0 0 0 1819512 0 0 0 0 +AAAQTALLAATSEIDKAC(Carbamidomethyl)TK MGYG000000179_02162;MGYG000000198_04035 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,220RQ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02162 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02968:RP-S20, rpsT; small subunit ribosomal protein S20 1.0 none 1.0 116066 0 0 0 0 142491 0 0 94407 0 0 0 0 0 0 0 0 0 0 0 0 125566 0 105754 0 106296 0 0 0 0 0 0 0 0 0 0 105369 297003 214112 0 521664 0 0 175447 0 0 220895 0 0 0 0 0 4915304 0 496099 0 0 0 0 110656 0 610413 0 447388 0 0 223849 0 0 0 309206 0 0 0 236243 195186 139759 0 0 0 0 143180 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101446 0 0 0 0 0 0 0 0 0 0 0 218900 0 0 0 0 0 0 0 0 0 0 0 0 0 96060 0 0 0 0 106079 0 241336 0 224524 0 0 0 0 0 0 90871 0 0 0 0 139656 901678 0 359702 0 0 0 0 0 738758 573674 0 0 0 0 671968 0 752283 0 0 0 0 375524 0 387914 0 649089 0 0 1137511 0 0 0 340985 0 0 0 257576 300382 +AAAQTDDMTRPFYPM MGYG000003452_01631;MGYG000002395_00808 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003452_01631 0.5 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K01621:xfp, xpk; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 542429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1200230 0 1573416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQTDDMTRPFYPM(Oxidation)LIFR MGYG000002459_00966;MGYG000003683_00701 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002459_00966 0.5 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K01621:xfp, xpk; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 142019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQTLGLNK MGYG000003683_01120 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG1841@1|root,COG1841@2|Bacteria,2GQV0@201174|Actinobacteria,4D1EZ@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Ribosomal protein L30p/L7e 1.0 rpmD 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02907 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L30 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01120 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02907:RP-L30, MRPL30, rpmD; large subunit ribosomal protein L30 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2568411 0 0 3571390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1637925 0 4618066 0 0 0 0 0 0 0 0 2359670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAQVPLSVAETAYK MGYG000001367_04132 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q symbiosum|m__MGYG000001367 1.0 COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,24JZM@186801|Clostridia,223XR@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Formiminotransferase-cyclodeaminase 1.0 fchA 1.0 - 1.0 4.3.1.4 1.0 ko:K01746 1.0 ko00670,ko01100,map00670,map01100 1.0 - 1.0 R02302 1.0 RC00688 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTCD_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001367_04132 1.0 formimidoyltetrahydrofolate cyclodeaminase. formiminotetrahydrofolate cyclodeaminase. In eukaroytes, occurs as a bifunctional enzyme that also has EC 2.1.2.5 activity. 5-formimidoyltetrahydrofolate + 2 H(+) = (6R)-5,10- methenyltetrahydrofolate + NH4(+). 1.0 1.0 1.0 1.0 One carbon pool by folate|Metabolic pathways 1.0 K01746:E4.3.1.4; formiminotetrahydrofolate cyclodeaminase [EC:4.3.1.4] 1.0 none 1.0 0 0 0 0 0 423579 0 0 0 0 0 0 0 388934 0 0 0 0 0 0 0 431194 0 0 0 0 0 0 721213 0 0 0 0 0 0 306137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3293055 0 1929659 3727238 0 0 0 0 0 0 4090868 0 0 0 0 0 0 0 2329018 0 2760395 0 0 0 0 3937869 0 0 0 0 0 0 3316477 0 0 +AAARPSAEYHAK MGYG000002517_02750;MGYG000004719_01514 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1197@1|root,COG1197@2|Bacteria,2NNMM@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 L 1.0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site 1.0 mfd 1.0 - 1.0 - 1.0 ko:K03723 1.0 ko03420,map03420 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03400 1.0 - 1.0 - 1.0 - 1.0 CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF,UB2H 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02750 0.5 - - - - 1.0 1.0 1.0 1.0 Nucleotide excision repair 1.0 K03723:mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76991 0 0 0 0 0 0 0 0 0 0 0 0 725859 0 0 0 0 0 0 0 0 0 0 0 0 979986 691643 0 693368 0 0 0 0 0 0 0 603967 699245 0 0 0 0 0 0 0 0 0 0 684421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAS(Delta_H(4)C(2)O(-1)S(1)[S](Ser->Met)ESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 736485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1162654 0 656456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 937257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303045 0 583352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 689202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1073361 0 675735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 562691 0 511821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASAEPQR MGYG000002775_00203;MGYG000002947_01254;MGYG000002065_00857;MGYG000000333_00086;MGYG000000188_00614;MGYG000002961_00869;MGYG000001642_00416;MGYG000004681_01110;MGYG000003266_01473;MGYG000001718_00567;MGYG000004746_00769 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4CUMW@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002775_00203 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682855 189800 0 0 388588 0 0 0 0 0 0 0 0 0 175509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104793 206633 0 0 181981 0 0 0 0 0 0 0 0 0 222168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 509708 514969 0 0 460058 0 0 0 0 0 0 0 0 0 70247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1336277 523542 0 0 433575 0 0 0 0 0 0 0 0 0 606679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASASF(Oxidation[F](Phe->Tyr)GYNEEPIVSSDVIGMR MGYG000004810_01402 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__CAG-272|g__UMGS1815|s__UMGS1815 sp900555345|m__MGYG000004810 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004810_01402 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1620557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 526898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 536242 0 0 0 0 0 0 0 0 0 0 0 0 +AAASE(Ammonium)SFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASE(Cation_Ca[II])SFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587419 +AAASE(Cation_Fe[II])SFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 738792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASE(Glu->Gln)SFGYNEDAIVSSDVIGMK MGYG000000179_02084 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02084 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1377364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASE(Methyl_2H(3))SFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASEPQSGR MGYG000002494_03460 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1MUAG@1224|Proteobacteria,1RMS6@1236|Gammaproteobacteria,3ZKP2@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Signal transducing histidine kinase, homodimeric domain 1.0 cheA 1.0 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145 1.0 2.7.13.3 1.0 ko:K03407 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW,CheY-binding,H-kinase_dim,HATPase_c,Hpt,Response_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03460 1.0 histidine kinase. protein kinase (histidine). This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine).-!-A number of histones can act as acceptor. ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03407:cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 842189 1081954 538711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 910021 0 0 0 0 1169995 0 0 740557 592116 0 0 0 805353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESF(Oxidation[F](Phe->Tyr)GYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGY(methylol)NEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 529801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYN(Deamidated)EDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1163056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 876996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYN(Deamidated)EDQIVSSDVIGM(Oxidation)R MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYN(Deamidated)EDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1792257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 837161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYN(Deamidated)TDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004884_01637 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 863999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392804 0 0 0 0 939721 0 0 0 0 2260517 0 0 0 816681 191586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360843 0 0 0 0 0 0 0 0 0 108302 0 0 265587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385319 0 0 0 0 292808 0 0 0 0 483417 0 0 0 602784 454209 0 0 0 0 371088 0 0 259022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 701122 0 0 0 0 520593 0 0 0 228954 456783 0 0 0 0 276459 0 0 239704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 370074 0 0 0 0 0 +AAASESFGYNE(Ammonium)DQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNE(Cation_Ca[II])DQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 923596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNE(Cation_Na)DPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1485108 0 0 0 0 1555212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1037199 0 0 0 0 0 0 0 0 0 1224896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1358554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNE(Cation_Na)DQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1508815 0 0 0 0 0 0 0 0 0 1457374 0 0 0 0 0 0 0 0 0 0 0 2734858 0 2274646 0 0 0 0 0 0 0 0 0 0 1711095 0 2433962 0 0 0 0 1979741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 988152 0 0 0 0 931979 0 0 0 0 1159346 0 0 0 0 0 0 0 0 0 0 0 0 2581742 0 0 0 0 0 1923649 0 1964746 0 0 0 0 0 0 1076239 0 0 3024648 0 0 0 0 0 0 1421188 0 0 2820693 0 2497154 0 0 0 1805955 2194334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNE(Methyl_2H(3))DQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 576842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNED(Ammonium)QIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 231102 0 0 0 0 0 0 0 0 245776 0 434703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 465645 0 0 0 0 0 0 330906 0 0 0 0 0 0 0 0 423639 0 304713 761021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480654 0 0 0 0 0 0 688573 0 0 0 0 0 0 0 0 0 0 0 1127402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNED(Cation_Ca[II])PIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422900 0 0 0 0 460201 0 0 0 0 403932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 108895 0 0 0 0 217626 0 0 0 0 263709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448859 0 0 0 0 426036 0 0 0 0 293687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 455223 0 0 0 0 814107 0 0 0 0 922613 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNED(Cation_Ca[II])QIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 462761 0 302924 213913 0 280651 156325 0 0 0 238929 219723 297344 333983 0 0 0 0 0 382019 0 250258 0 273924 391517 125209 239994 0 0 108550 346445 0 401601 604301 0 118826 161428 496205 429460 0 628214 539339 0 456716 707599 0 0 0 348625 564053 222824 499885 791603 0 0 0 0 903956 0 312878 0 309056 848015 364219 661467 0 0 641952 690127 698449 557768 566795 0 529844 511814 607399 185470 0 0 0 0 150545 81092 0 0 0 334488 0 82546 79360 79619 0 0 0 0 0 0 0 0 295142 0 138993 160700 0 0 0 0 0 0 146196 0 119524 0 0 562830 0 943200 555496 0 782988 0 0 0 0 650723 724355 1086578 857072 511937 0 0 0 0 709317 0 952073 0 798298 0 703723 780706 0 0 761123 871261 660052 765788 892564 0 535284 594017 0 0 0 271614 161982 0 0 556130 0 0 0 0 0 0 550140 644769 0 0 0 0 0 0 0 0 0 446727 0 554881 0 0 0 637915 535523 722871 532226 0 429597 0 142115 +AAASESFGYNED(Cation_Fe[II])QIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 918471 0 0 136643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161286 0 164502 0 0 0 0 0 0 0 0 0 235986 0 0 0 0 0 0 641842 0 0 454889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310050 0 470096 0 0 0 0 0 0 0 0 162793 521877 0 0 0 427597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 714408 0 0 786551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 834757 0 864323 0 0 0 0 0 0 0 0 0 612158 0 0 0 649951 0 0 511278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298400 0 0 0 0 0 0 0 0 0 0 402349 243711 0 0 0 583438 +AAASESFGYNED(Cation_Na)PIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 190885 0 0 0 0 307592 0 0 0 0 0 0 0 0 0 393567 0 0 0 0 0 0 0 0 0 0 0 0 0 289021 0 0 0 0 0 0 0 1619961 289368 0 0 0 0 1387503 0 0 0 0 0 0 0 0 0 0 0 1247387 0 0 0 0 0 0 0 0 0 0 0 396143 0 0 0 0 0 0 0 1045751 468801 0 0 0 0 783509 0 0 0 0 888937 0 0 0 0 853887 0 761585 0 0 0 0 0 0 0 0 0 0 0 605352 0 0 0 0 0 0 0 707003 813179 0 0 0 0 0 0 0 0 0 1130190 0 0 0 0 0 0 750190 0 0 0 0 0 0 0 0 0 0 0 441941 0 0 0 0 0 0 0 0 307963 0 0 0 0 1893361 0 0 0 0 2027283 0 0 0 0 2411531 0 771119 0 0 0 0 0 0 0 0 +AAASESFGYNED(Cation_Na)QIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 1226962 1094675 1897071 1218810 212599 905393 943994 586800 1112082 930906 0 921218 1253189 1095191 596708 717775 1095480 682721 1507563 1227562 477244 597557 680873 802135 778936 773288 837981 948799 0 529149 1402857 896863 0 1443888 0 1007184 1091883 1429249 1755077 1729392 2208148 1964362 0 2099991 2895943 943190 1729285 581171 0 2185790 1814735 1954658 2570919 1931181 0 1422002 0 2909238 1251944 1701503 1482603 2307986 2775580 2088722 2180761 1322552 0 0 2191095 0 1836684 2018086 0 1826316 0 1880812 457912 369849 419225 485264 414532 415761 380836 0 365085 246330 0 401454 249901 280816 410136 264428 343316 924597 279514 416907 330000 317695 896156 513946 412740 509529 406049 760795 0 426681 357137 477786 329425 427617 0 306335 174643 436325 1439643 1827436 0 1653181 1823558 2331827 2883469 792867 0 1470196 0 2561120 2933421 2086031 1533068 1990964 2031833 0 2406534 2010255 0 2657373 1488254 2393913 2567040 1881093 1904345 1386765 0 1936950 0 1964801 0 2344758 0 1686358 0 0 444763 461086 728902 255274 424630 248176 206156 422511 749584 707295 0 357039 213263 318290 700556 441360 628430 1603259 183445 216861 384870 542729 350542 395522 612442 830713 680651 1255833 0 918184 440085 286193 755599 646630 0 619503 986382 1025152 +AAASESFGYNED(Methyl_2H(3))QIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 288662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 643024 0 474574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNEDAIVSSDVIGMK MGYG000000179_02084 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02084 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 322934 0 231162 247256 0 0 386385 0 376332 218120 337747 0 0 312862 109495 0 255142 0 0 0 244281 307757 0 0 219131 391404 171720 0 462517 388128 0 0 717956 190123 0 0 362747 162986 0 0 306994 317436 0 0 0 0 322592 0 331328 0 0 289367 0 0 0 0 0 425898 193212 545396 0 208065 0 0 280773 0 0 362312 0 0 0 304488 0 217556 0 232303 425915 0 163323 0 0 0 207384 0 98037 0 138913 0 0 180911 236139 0 0 0 0 263599 0 0 0 0 0 431925 0 0 463058 0 0 0 0 0 0 192621 0 0 286523 0 298877 544474 0 341728 156955 0 747955 248218 86918 0 0 746057 300407 0 315331 0 0 407874 425542 0 0 0 398738 0 259173 0 245675 191165 0 0 319994 170805 0 364866 272257 0 3254936 0 1184003 1957933 0 750891 1514889 0 2192657 2122244 1216619 0 0 2985195 2321025 0 1771321 0 1978511 2906171 1731926 1770596 0 1549331 1803795 2946690 2477738 0 3201244 1797254 0 0 1511655 2907456 0 2782549 3651375 1703499 +AAASESFGYNEDAIVSSDVIGMR MGYG000001311_02933 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000155435|m__MGYG000001311 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001311_02933 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 799463 0 0 0 0 0 0 0 704029 0 0 0 0 0 0 0 0 0 0 0 0 675342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189435 0 0 0 0 0 0 0 355768 0 0 0 0 0 0 0 0 0 0 0 0 254338 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153743 0 0 0 0 0 0 0 131861 0 0 0 0 0 0 0 0 0 0 0 0 336688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402170 0 0 0 0 0 0 0 255505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534658 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNEDL(Xle->Gln)IVSSDVIGMR MGYG000001255_00370 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_F|m__MGYG000001255 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001255_00370 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1656053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNEDP(Pro->Gln)IVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 2673808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 983409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNEDPIVSSDVIGM(Oxidation)R MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 980692 0 0 0 0 0 821586 0 0 0 0 653960 0 0 0 0 613786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 988294 0 0 0 0 0 929010 0 0 0 0 1101139 0 0 0 0 729904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609747 0 0 0 0 0 711767 0 0 0 0 956302 0 0 0 0 1691034 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1188520 0 0 0 0 0 1083257 0 0 0 0 1114323 0 0 0 0 1549262 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNEDPIVSSDVIGMK MGYG000003510_00403 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__UBA6857|s__|m__MGYG000003510 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003510_00403 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641277 0 0 0 0 0 0 404253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNEDPIVSSDVIGMR MGYG000000258_00590;MGYG000001606_02632;MGYG000000242_02076;MGYG000001954_02254;MGYG000001619_01736;MGYG000000084_01085;MGYG000001627_00130;MGYG000000278_03657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 0.875 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000258_00590 0.125 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 603273 452539 498636 0 0 533683 0 903044 227628 0 203127 0 398740 0 411048 444886 609129 482912 0 0 0 425135 905074 249835 0 0 0 789335 0 0 686431 0 391637 0 0 214546 560039 231357 866057 638511 809653 1071513 727104 650551 943036 1105159 746380 958009 769278 6002596 867346 1019367 1003118 634503 828590 4871421 726601 987559 904003 786369 5454693 0 893449 1106009 0 5197341 1040895 4041175 1100366 419117 770297 849379 936038 946552 910171 690796 1370600 1602976 1339954 1134852 851388 1126665 1359665 1766557 1472481 1628967 1267132 3142538 1789098 1467217 1988464 1323445 1496045 2414873 1531668 1560293 1556414 1335532 2290851 875153 1350611 1634822 1657218 3187826 1401826 2808620 1006009 1173613 1365993 1949527 1952554 1449589 1812739 1695683 1972943 1678371 1586476 1912548 2107705 2129950 1573005 1759738 1752197 1837661 1846385 2461887 2169236 1564738 1357541 2144622 2010716 3297307 1346833 1742728 1537158 2347855 3113957 2306538 2097245 1453970 2036016 4518272 2373270 2449672 2065717 1329828 1539759 835205 1209029 1404706 1215859 1878783 1386468 1824362 1630936 1398852 1094356 1070325 1460741 1703970 1148574 1054657 1621671 4971665 1420068 2215776 1277563 1263231 1189301 5746827 998911 1073390 1829984 1250764 6811836 1518200 1909771 1463965 1777320 7202305 2206664 2553994 1938969 1667068 2216586 1562104 1854380 2127314 1490630 1567348 +AAASESFGYNEDQIVSSDVIGM(Oxidation)R MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 666624 844872 1069777 918282 0 618630 609528 0 514144 318303 900291 521983 695183 511855 723065 959293 1443038 1103023 979619 728523 318954 1478075 470709 765705 726543 1051861 364642 482156 0 211636 795543 591499 1074792 861300 0 745910 518205 883954 867573 1043824 974174 1630904 1184023 1466375 2010093 0 3028262 357695 1174653 1826928 284736 0 1450873 1250188 1461273 1683660 1501753 1205037 723525 759537 1101860 1633722 1568271 1019459 1140101 910171 0 1159004 2087483 1343059 1031949 1140878 0 1221705 1444878 1872507 587332 597506 359968 604461 479735 495957 500818 0 417396 448012 607346 389868 383663 464716 438246 523850 464194 1272602 232616 346315 365048 321812 1200462 261749 338080 494640 417871 1287838 0 392995 361838 381103 307178 323240 0 300468 325726 512920 1473247 1566775 2323435 1491214 1336438 1715923 1822512 0 1333636 1103224 1689047 2381848 2557015 1712587 1394156 1358547 1556865 1081162 2193289 1747797 1730642 1879698 1586967 1925232 1253333 1393929 1103293 1293907 0 1892415 2106916 0 1886916 1808502 0 1274122 1717084 1881644 317692 329384 314369 1367245 0 149284 182455 0 1911569 923508 163071 1297622 1053632 1224789 190065 1500998 447244 270359 272442 351703 1472352 0 304865 285253 197942 179440 194787 313804 0 915460 188771 834812 451099 1733956 0 872568 313364 303704 +AAASESFGYNEDQIVSSDVIGMK(Lys->Arg) MGYG000004087_02290;MGYG000003431_01105 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004087_02290 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2311483 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3733746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402207 0 0 0 0 566725 0 0 0 0 545056 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNEDQIVSSDVIGMR MGYG000000150_00838;MGYG000000362_01155;MGYG000000836_00852;MGYG000001300_02008 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 C 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.75 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000150_00838 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 3696553 4502717 7428028 6024758 492492 3440633 3782790 2239322 4286968 3320297 3826809 0 4565398 4218696 2335908 3502254 4096399 0 6930280 3860357 1487416 2963776 2917439 3358721 3526261 3757754 3520132 3432443 1165323 0 5459414 2866620 5632270 6798639 1970225 3378705 3562177 5262245 7718420 6174612 8832362 9010803 6062558 10457755 0 4026947 6909045 1696823 0 10586856 7286481 8287354 11583192 7272654 11155792 5487603 10989296 15451344 5080823 8577483 0 9432662 12107354 8347263 8754037 0 0 6515289 9444611 11106114 6210661 6553758 2464669 6245733 7278113 8091513 1301979 0 698582 0 1118227 991734 1883799 914749 0 753280 0 0 1121291 0 1161559 1373598 801270 3269347 1028995 1377878 1044428 859820 3203316 1008699 1343201 1586550 0 0 586276 1095032 0 1819524 737595 1300617 898479 1351436 1146178 643068 5192124 6706602 10356606 7978650 6604844 8412571 10157402 2720436 6184666 5265362 6606838 8815837 9853604 9053380 5078261 8576267 7073355 3558511 9661767 9552363 7914630 9816255 4369787 7632982 8208870 7007172 6765479 4472111 2702696 7786448 10189819 10065239 9167360 11060590 0 5652726 6238409 7932428 359089 322066 201689 288014 596487 227543 256768 176261 390303 298157 223451 224853 294417 336825 208303 329092 542691 578649 233711 256488 239821 381365 707068 659070 331149 257618 201613 730051 409378 441014 276092 466414 322837 271063 759773 156035 247869 457822 +AAASESFGYNT(Formyl[T](Thr->Glu)DPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004884_01637 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 840379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 935580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESFGYNTDPIVSSDVIGMR MGYG000004884_01637;MGYG000000231_00608;MGYG000000193_03247;MGYG000001707_00061;MGYG000000036_01872 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 0.6 186801|Clostridia 1.0 G 0.6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004884_01637 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 1733013 1749701 1681142 1778430 0 1868811 1558526 1785705 2609155 0 1875900 1338916 1194332 1566555 1742558 3845741 1029215 1251730 1173798 1620580 3091149 1073914 1445697 0 0 4459969 0 0 1651659 1621357 1189924 0 1345676 0 0 1338674 0 0 0 238176 0 0 0 0 0 0 356487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326669 0 0 0 0 0 0 0 0 0 0 0 0 317837 524309 0 0 0 0 0 413248 255387 0 164879 552691 546738 592649 0 351056 451533 487079 0 433862 387602 364370 459914 0 0 718505 0 0 300448 360293 499629 0 360290 0 0 312719 0 0 739363 608194 557940 767804 0 782505 723900 543865 711456 0 656986 514353 834814 432931 578175 1241159 425503 560599 455077 538293 818305 516961 755907 0 0 2364166 0 0 769694 593591 389632 0 337265 0 0 447692 0 0 666102 564537 282186 388808 0 400583 487637 560509 1465251 0 759967 840062 667830 461172 276155 379399 525403 382739 491350 446246 859596 555671 591369 0 0 935316 0 0 860947 664127 676772 0 863208 0 0 665224 +AAASESYGYNEDPIVSSDVIGMK(Lys->Arg) MGYG000002946_02881 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp900555905|m__MGYG000002946 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,21XGY@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Glyceraldehyde-3-phosphate dehydrogenase 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002946_02881 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASESYGYNEEQIVSSDIVGM(Oxidation)R MGYG000003552_01242 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-127|s__CAG-127 sp900539705|m__MGYG000003552 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003552_01242 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASLGALGFK MGYG000004797_00778;MGYG000002478_01127 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_00778 0.5 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 1165977 0 987513 0 0 599888 0 536986 0 0 0 958711 0 1125545 0 0 866201 0 0 0 0 0 0 0 0 0 0 0 0 0 1067478 0 0 0 0 986540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 235253 0 0 0 0 0 0 0 0 0 0 94339 0 184516 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252572 0 0 0 0 182941 0 0 126519 0 0 0 0 130094 0 229154 0 0 0 111267 0 0 0 0 187639 0 0 0 0 0 0 0 0 0 0 0 0 0 73580 0 0 0 0 300019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASLGEMGFR MGYG000000029_02049;MGYG000000236_03409;MGYG000001345_04416;MGYG000004876_01120;MGYG000003681_02554;MGYG000003363_00071;MGYG000001346_01988;MGYG000000196_02827 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000029_02049 0.125 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 301471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1125149 0 0 0 0 0 0 0 0 0 0 0 0 563876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASLPDIR MGYG000002478_00527 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1435@1|root,COG1435@2|Bacteria,4NFWU@976|Bacteroidetes,2FNY3@200643|Bacteroidia,4APFH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00527 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 2146439 1684424 1187356 1967090 1839862 1927532 1879587 0 1854923 0 0 0 0 2007741 0 2160120 1848473 0 1827204 0 2189367 2026515 0 2588260 1658367 2126812 1910868 0 2146543 1944021 0 2164646 1457128 0 2100614 0 1935628 1396073 947383 755646 1066138 1013860 567295 996975 735378 0 1196788 0 0 0 0 1165928 0 965114 686163 0 974925 0 814115 823805 0 788780 1084706 992317 801252 0 898623 634073 0 697877 1376678 0 973793 0 971218 876549 956477 580142 747265 982720 1073172 942551 953804 0 1002613 0 0 0 0 842457 0 737205 870618 0 1065600 0 678655 538165 0 824550 793414 717496 862309 0 908713 659580 0 560983 769978 0 610633 0 801956 784574 161257 0 0 180174 0 247284 136202 0 117510 0 0 0 0 141740 0 155927 0 0 321368 0 404188 0 0 0 145597 300442 0 0 220324 171577 0 278167 202394 0 285650 0 155533 135010 838527 717011 632442 710225 1297231 1097305 968613 0 1220170 0 0 0 0 438678 0 1169139 768133 0 983824 0 563031 949929 0 859617 713091 520706 575946 0 602176 1297262 0 563957 442166 0 828609 0 835502 778802 +AAASQEMTLVDTPNAK MGYG000002494_03091 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS 1.0 proS 1.0 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.15 1.0 ko:K01881 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03661 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iUTI89_1310.UTI89_C0210 1.0 HGTP_anticodon,tRNA-synt_2b,tRNA_edit 1.0 - 1.0 - 1.0 - 1.0 CBM50+GH25 1.0 MGYG000002494_03091 1.0 proline--tRNA ligase. prolyl-tRNA synthetase. - ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01881:PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15] 1.0 none 1.0 0 0 0 0 286964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169328 0 0 333276 0 354788 776280 0 836975 0 643962 965663 0 558937 0 834829 0 523098 0 0 0 0 0 0 0 0 0 1264675 0 980348 713001 601480 0 0 0 0 0 0 953071 0 0 590390 566308 690619 0 0 0 0 0 0 0 0 0 137212 0 295183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245339 0 298223 451065 0 323884 0 266854 0 0 186812 0 252324 0 0 0 0 0 0 0 0 0 0 0 167457 0 471878 281266 252435 0 0 0 0 0 0 294803 0 0 162221 0 370056 +AAASQSFGYNEDPIVSSDVIGM(Oxidation)K MGYG000003937_01177 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01177 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1167846 0 0 0 0 568376 0 0 0 0 765948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASQSFGYNEDPIVSSDVIGMK MGYG000003937_01177 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01177 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 1899388 2061579 2342298 1807186 1872489 1953133 1546716 2763143 2063933 2954897 2740430 2626570 2664147 1831230 1851179 2506245 1971429 3823268 2336666 1951527 1911422 1785558 2505716 1171544 2150712 1750064 1866015 3694295 2798570 2204370 1358622 1475302 1312477 1758362 1717153 1689334 2026221 1546192 0 213158 0 0 0 0 292407 0 0 0 0 0 0 223296 0 0 0 462469 165101 162706 0 0 305584 0 0 0 0 456288 203164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292457 244541 0 323959 355523 0 259311 0 235282 0 243121 122288 277821 0 0 252459 237156 244441 241709 276470 0 0 353447 204704 337648 0 0 288286 400833 295984 0 243321 0 522352 571053 383498 485947 786710 530315 463599 425378 486339 532287 563636 667521 626859 511820 388807 651321 691366 670959 280247 440939 310950 699440 359287 445578 460332 354610 585049 997709 437968 521980 629514 283650 479868 364609 408460 385805 400123 364079 838147 547565 520171 0 683147 336902 204166 609854 950194 206273 548024 746090 0 868831 937754 189328 1084692 180227 510621 0 884021 722498 242068 374769 500603 502311 368397 312577 0 498378 788534 0 562757 762405 486011 906708 835713 905070 +AAASSAAPAEDVTIK MGYG000003166_01579 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539885|m__MGYG000003166 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_01579 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10200:ngcE; N-acetylglucosamine transport system substrate-binding protein 1.0 none 1.0 0 0 0 988017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASSFNK MGYG000000198_05930 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Cell wall-binding repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_05930 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 92493 0 723679 413207 621080 187545 532280 210960 500604 172388 1099304 352614 1367781 66538 432093 758328 202484 0 178845 171601 267689 85024 0 273235 289727 292429 388708 0 253837 272310 0 203972 1381755 270387 0 329735 303874 1087348 163079 0 165126 136261 573010 429966 178425 163125 200587 264291 1366220 142480 1638987 197558 192899 741492 191201 0 254738 163420 309854 215939 0 487188 294167 166054 86364 0 401383 267494 0 302734 186445 158798 0 163327 138715 199641 4750057 0 4484537 5251455 3395817 2081346 2943706 3389098 5491576 1510508 3507163 4240238 4821611 5776110 6531190 4067992 1943736 0 5319960 6432734 6586443 3533686 0 4060824 2243397 5186218 7812961 0 8529902 2185307 0 2007862 3375658 5156814 0 7287413 5887150 4040334 218465 0 251836 241195 97653 211534 97406 160456 296677 176115 756731 0 180049 249961 166227 223336 145603 0 198658 230400 93072 278895 0 175472 104226 300716 80617 0 175693 196538 0 131146 0 0 0 111108 189221 180484 194381 0 164839 395646 445046 239665 175050 241056 412132 0 972718 297206 1665761 447526 128953 592313 243049 0 208566 175095 0 196906 0 771991 379071 433797 366521 0 0 293576 0 0 0 308471 0 282202 0 267278 +AAASSLGM(Oxidation)AEKVAK MGYG000000196_04005 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia,4AQZ3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04005 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2020404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASSLGMEAMPK MGYG000002478_00783 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia,4AQZ3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00783 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1198583 0 0 0 0 362812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASSPALTAVVAQSEYANLQR MGYG000003937_01616 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG2182@1|root,COG2182@2|Bacteria,1VRPK@1239|Firmicutes,24Y63@186801|Clostridia,3WJGG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01616 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K15770:cycB, ganO, mdxE; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 836195 0 0 0 0 876942 0 0 0 0 772412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 840057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAASYLDLPLYR MGYG000002549_00850;MGYG000000196_01187 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0148@1|root,COG0148@2|Bacteria,4NF5M@976|Bacteroidetes,2FMNI@200643|Bacteroidia,4AM0T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000002549_00850 0.5 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 221336 0 0 0 0 0 0 0 264536 0 0 0 0 92639 0 279585 0 0 0 250080 93315 0 0 223068 0 0 0 383208 281940 0 0 0 245748 0 0 311453 152440 1092039 1126944 1369783 0 0 1347291 1317234 0 1171842 1556931 0 0 0 1591364 1884883 0 1247868 0 0 1392581 1509922 1312684 0 1112100 1449828 1625209 0 0 1242369 1536998 0 0 1146910 1421998 0 0 1569179 1289166 303083 0 245012 0 0 126561 327101 0 261207 204133 0 0 0 271803 119672 0 329081 0 0 214046 265623 0 0 99778 231484 238197 0 0 294130 194625 0 0 252825 471545 0 0 317201 280325 423794 356556 257521 0 0 237818 406633 0 373981 277851 0 0 0 359360 455127 0 262879 0 0 345127 428705 445962 0 214542 460113 567343 0 0 468499 322067 0 0 198590 227488 0 0 492401 170200 834382 609444 166652 0 0 946210 920745 0 964107 580550 0 0 0 894252 571245 0 935748 0 0 983795 858104 617379 0 870821 1167188 1058032 0 0 1197581 955059 0 0 808026 886047 0 0 1087438 678373 +AAATAADKAR MGYG000004733_00775;MGYG000001338_01157;MGYG000000133_00993;MGYG000000301_01128 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_00775 0.25 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7586 0 0 0 0 0 0 0 0 12795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102333 0 0 0 0 0 0 622159 0 0 0 0 0 0 116135 0 829475 0 0 0 0 0 0 0 0 27989 0 0 0 0 0 0 0 0 0 0 33527 0 +AAATAADKM(Oxidation)R MGYG000000315_00696;MGYG000000031_00643;MGYG000000142_00071 domain d__Bacteria 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 0.6666666666666666 186801|Clostridia 0.6666666666666666 C 1.0 Psort location Cytoplasmic, score 9.98 0.6666666666666666 adhE 0.6666666666666666 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000315_00696 0.3333333333333333 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAATAADKMR MGYG000000315_00696;MGYG000000031_00643;MGYG000000142_00071 domain d__Bacteria 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 0.6666666666666666 186801|Clostridia 0.6666666666666666 C 1.0 Psort location Cytoplasmic, score 9.98 0.6666666666666666 adhE 0.6666666666666666 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000315_00696 0.3333333333333333 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 142847 266679 725891 140081 609608 0 54717 804689 0 0 1668594 0 575033 0 793280 0 530015 0 0 0 0 0 0 0 0 267716 429850 0 304587 0 337993 0 0 448912 426734 77098 101573 540230 804334 1267555 725560 400519 2063647 0 1423402 1084211 0 0 1858493 0 722173 0 745609 0 653775 0 0 0 0 0 0 0 0 907157 1362205 0 1060547 0 2042047 0 579871 1135863 711311 831436 547244 477898 47618 154090 182964 43474 33800 0 37463 64178 0 0 91399 0 152203 0 55366 0 43187 0 0 0 0 0 0 0 0 51809 139321 0 114594 0 73965 0 367136 177946 146179 0 41234 133018 42440 52161 44954 0 261867 0 257316 0 0 0 102612 0 115986 0 0 0 289394 0 0 0 0 0 0 0 0 0 245228 0 177881 0 0 0 180186 96133 0 0 126415 71714 138453 252948 346785 63240 49583 0 162315 145022 0 0 305889 0 182190 0 82822 0 120219 0 0 0 0 0 0 0 0 134224 81024 0 140781 0 276993 0 424808 147515 89508 255829 206135 153986 +AAATAANQM(Oxidation)RIPLAK MGYG000001754_00010 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-110|s__CAG-110 sp900752285|m__MGYG000001754 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001754_00010 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 3219964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3275736 0 3188817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1041952 0 632209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAATEATPAAETAAPVAEAPAAEEAKAE MGYG000001346_01491 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,2FNPH@200643|Bacteroidia,4AK8D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal protein L17 1.0 rplQ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02879 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Ribosomal_L17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_01491 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02879:RP-L17, MRPL17, rplQ; large subunit ribosomal protein L17 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 360562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310011 1239358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 901067 226023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2662709 555968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAATESFGYN(Deamidated)EELIVSSDIVGMR MGYG000000562_01218 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp000437735|m__MGYG000000562 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,25VFF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000562_01218 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269587 0 0 0 0 180048 0 0 0 0 421824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410657 0 0 0 0 448926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAATESFGYNEDEIVSSDIVGMR MGYG000002304_00547;MGYG000004735_01946 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27V6G@189330|Dorea 0.5 186801|Clostridia 1.0 C 0.5 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002304_00547 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 764530 0 0 0 0 0 1051826 1818087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2898386 0 0 0 0 0 2011549 1777339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525037 635626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1605007 231174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 25411828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAATESFGYNEDEIVSSDVIGMR MGYG000004493_00097 genome d__Bacteria|p__Spirochaetota|c__Spirochaetia|o__Treponematales|f__Treponemataceae|g__Treponema_D|s__|m__MGYG000004493 1.0 COG0057@1|root,COG0057@2|Bacteria,2J5AD@203691|Spirochaetes 1.0 203691|Spirochaetes 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004493_00097 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAATESFGYNTDEIVSSDIVGMK MGYG000001607_01815 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_B|s__Dorea_B phocaeensis|m__MGYG000001607 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001607_01815 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 501713 0 0 0 0 579870 0 0 0 0 872704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAATLMK MGYG000000243_01167 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,4ANQH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01167 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3096234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356402 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1111058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 768834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397892 0 0 0 0 0 0 0 +AAATQEMTLVDTPNAK MGYG000003372_01055;MGYG000002506_04331;MGYG000003365.1_03562;MGYG000000093_03470 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0442@1|root,COG0442@2|Bacteria,1MU7E@1224|Proteobacteria,1RN5R@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS 1.0 proS 1.0 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.15 1.0 ko:K01881 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03661 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iUTI89_1310.UTI89_C0210 1.0 HGTP_anticodon,tRNA-synt_2b,tRNA_edit 1.0 - 1.0 - 1.0 - 1.0 CBM50+GH25 1.0 MGYG000003372_01055 0.25 proline--tRNA ligase. prolyl-tRNA synthetase. - ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01881:PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15] 1.0 none 1.0 0 0 0 0 0 536441 0 0 0 372345 0 0 0 0 0 0 0 0 0 0 0 410056 0 347414 0 0 444823 0 0 0 0 0 0 0 384919 0 403703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1201562 0 0 0 542351 0 0 0 0 0 0 0 0 0 0 0 674835 0 1006390 0 0 0 0 0 0 0 0 0 0 0 0 434773 0 697824 0 0 0 0 854490 0 0 0 602905 0 0 0 0 0 0 0 0 0 0 0 917337 0 0 0 638607 861658 0 0 0 0 0 0 0 933494 0 311320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAATTPAGDGIQLSGNEVNITLKPGATPAVDPK MGYG000000243_02343 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 2DUE9@1|root,33Q7G@2|Bacteria,4P1S2@976|Bacteroidetes,2FQRY@200643|Bacteroidia,4APG5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Domain of unknown function (DUF5115) 1.0 - 1.0 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0005982,GO:0006073,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030246,GO:0030247,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044462,GO:0044464,GO:0071704,GO:0071944,GO:2001070 1.0 - 1.0 ko:K21571 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF5115,SusF_SusE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02343 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21571:susE_F; starch-binding outer membrane protein SusE/F 1.0 none 1.0 987370 1109964 1088290 1460842 1658939 987493 0 1216167 1194968 883046 0 0 0 0 799903 0 1285592 1061060 869272 795988 0 788056 1562992 918521 865514 1195290 1239258 1238649 0 1107521 1207557 1849571 1197688 1254995 0 1187634 850712 963085 0 0 0 0 356178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388616 0 0 0 0 0 0 0 0 218263 0 0 0 0 0 0 582836 464438 620283 399223 1267966 553450 0 525935 625954 475402 0 0 0 0 394580 0 366605 2183574 786971 251385 0 428784 1943218 561871 250523 496178 534530 1489635 0 398552 615350 574835 518647 382531 0 649422 464956 547129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVAAAK MGYG000001300_00438 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3WG9R@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 aconitate hydratase 1.0 acnA 1.0 - 1.0 4.2.1.3 1.0 ko:K01681 1.0 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 1.0 M00009,M00010,M00012,M00173,M00740 1.0 R01324,R01325,R01900 1.0 RC00497,RC00498,RC00618 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aconitase,Aconitase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00438 1.0 aconitate hydratase. citrate hydro-lyase. Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate.-!-The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate.-!-cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate.-!-Formerly EC 4.2.1.4. citrate = D-threo-isocitrate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Glyoxylate and dicarboxylate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K01681:ACO, acnA; aconitate hydratase [EC:4.2.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1447459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVAKEVEK MGYG000000271_02014 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02014 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVAKEVEKK MGYG000000271_02014 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02014 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVAVAAGPAAGAAAAEEK MGYG000001345_04691;MGYG000004797_04276;MGYG000002478_00807;MGYG000000236_01800 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_04691 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518984 0 0 0 0 649021 0 291949 0 0 0 0 622615 0 0 0 0 532272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 946379 0 0 0 0 680994 0 0 0 0 717609 0 0 0 0 0 0 0 0 0 0 +AAAVAVAAGPAAGGAAAAEEK MGYG000003697_01479;MGYG000002293_00514 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01479 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635871 0 0 0 0 254764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577755 0 0 0 0 0 0 0 0 0 356189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1294683 0 0 0 490771 2040322 292588 0 0 0 517702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378321 0 0 0 0 193246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVAVAGPAGAGAAAAEEK MGYG000004780_01209 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Neisseriaceae|g__Neisseria|s__Neisseria sp000186165|m__MGYG000004780 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,2KR8H@206351|Neisseriales 1.0 206351|Neisseriales 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004780_01209 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 711871 0 0 0 0 0 0 0 0 +AAAVDAR MGYG000000196_04766 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG3087@1|root,COG3087@2|Bacteria,4NU0A@976|Bacteroidetes,2FPJ1@200643|Bacteroidia,4AKB9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 D 1.0 Sporulation and cell division repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SPOR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04766 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 562069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVEAHDIDPNAK MGYG000002098_02080;MGYG000001658_01879 genus d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01 1.0 COG1053@1|root,COG1053@2|Bacteria,1UK5H@1239|Firmicutes,250H0@186801|Clostridia,26CIB@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002098_02080 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1180947 0 234265 0 0 638715 0 251509 0 0 0 0 0 595937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489302 0 2069163 0 0 970386 0 984379 0 0 0 0 1798763 2108032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1604700 0 1188668 0 0 1682174 0 2020192 0 0 0 0 2414761 1603787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3604661 0 754608 0 0 5171285 0 1555699 0 0 0 0 2204588 5183887 0 0 0 0 0 0 0 0 0 +AAAVEAPK MGYG000003122_01008 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900541235|m__MGYG000003122 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,2GJU4@201174|Actinobacteria,4CUBT@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 TIGRFAM PTS system, fructose subfamily, IIC 1.0 - 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS_EIIA_2,PTS_EIIC,PTS_IIB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003122_01008 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Phosphotransferase system (PTS) 1.0 K02768:fruB; fructose PTS system EIIA component [EC:2.7.1.202]|K02769:fruAb; fructose PTS system EIIB component [EC:2.7.1.202]|K02770:fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 698171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1147553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1266436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVEASKN(Deamidated)GAEK MGYG000002528_01429 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DAO,FAD_binding_2,FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01429 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVEQLQVWGQR MGYG000002535_04546;MGYG000002506_03085;MGYG000002494_02119 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0552@1|root,COG0552@2|Bacteria,1MUDU@1224|Proteobacteria,1RNIN@1236|Gammaproteobacteria,3WWK2@544|Citrobacter 0.3333333333333333 1236|Gammaproteobacteria 1.0 D 0.6666666666666666 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components 1.0 ftsY 1.0 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019897,GO:0019898,GO:0031224,GO:0031226,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033036,GO:0033365,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 - 1.0 ko:K03110 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 COX15-CtaA,SRP54,SRP54_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002535_04546 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03110:ftsY; fused signal recognition particle receptor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 717101 0 409945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 349557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVGLK MGYG000003022_00736;MGYG000004642_00845;MGYG000000187_02028 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1MUCV@1224|Proteobacteria,2VI3Q@28216|Betaproteobacteria,1KJ5X@119065|unclassified Burkholderiales 0.3333333333333333 186801|Clostridia 0.6666666666666666 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000003022_00736 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3332341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVIDK MGYG000001300_00243 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00243 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 1121836 0 0 275011 0 0 0 0 0 0 13716986 0 0 0 0 0 0 0 0 1393270 1125634 483335 0 0 0 0 0 0 0 0 0 0 0 0 0 622937 0 0 531534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11526450 0 15639591 8694036 0 0 0 0 0 0 14145406 0 0 0 0 0 0 0 0 15619664 0 17180558 0 0 0 9699647 0 14985083 12095320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVLDK MGYG000001300_00243 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00243 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 9565049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16083675 13196231 0 0 0 0 20570030 0 0 0 10070606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13536473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVLLQR MGYG000001315_02695 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0607@1|root,COG0607@2|Bacteria,1V09Z@1239|Firmicutes,24AZV@186801|Clostridia,21ZFU@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 P 1.0 Rhodanese Homology Domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rhodanese 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_02695 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1039279 0 1592213 421962 1049596 709782 0 0 0 859882 1166162 1014172 0 0 0 777879 0 0 746402 908337 0 769203 0 941188 0 833209 596730 0 0 0 0 872514 1773736 0 846288 0 642766 1748631 2063089 0 4042782 1913121 2436600 1874639 0 0 0 2485081 2383348 2004951 0 0 0 2640244 0 0 2079142 1702186 0 0 0 1550119 0 1658487 2268608 0 0 0 0 3729638 5188509 0 2637418 0 1815774 3705560 527645 0 120063 0 299655 394252 0 0 0 367654 169169 292656 0 0 0 0 0 0 0 0 0 101030 0 253774 0 267744 681369 0 0 0 0 0 163350 0 0 0 317902 97660 101269 0 363831 0 0 0 0 0 0 0 0 416944 0 0 0 0 0 0 0 449688 0 0 0 126564 0 387526 438064 0 0 0 0 0 0 0 0 0 383434 0 1335240 0 2518144 1504560 2221180 991307 0 0 0 1095201 480838 1050693 0 0 0 866599 0 0 1288627 1975421 0 1383575 0 972482 0 1603336 866266 0 0 0 0 513768 1567245 0 1521133 0 1237383 3001731 +AAAVMEALR MGYG000001617_00231 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp900547735|m__MGYG000001617 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,21Y1Y@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000001617_00231 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVN(Deamidated)IVPNSTGAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_02459 0.011111111111111112 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 265213 0 0 0 214313 0 0 0 0 0 0 0 0 0 0 1131309 0 205872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 509012 0 860197 0 0 0 907635 710554 0 298729 0 0 0 218113 0 0 0 128814 0 0 338602 0 388997 0 0 167732 393710 0 0 0 246572 0 0 319034 0 158769 0 0 0 0 2100470 0 0 1940119 1504377 0 0 1445399 0 1821617 0 1401178 0 1162859 1400923 1461837 0 0 0 0 1512047 0 1559972 1479660 2526548 0 0 0 0 1893032 0 1691930 0 0 0 0 1705681 0 1006256 0 0 664186 0 0 0 0 0 912432 0 570135 0 1419646 0 233731 0 0 0 0 884715 0 0 0 0 0 0 0 1280454 533783 0 844110 0 1074897 0 0 630307 0 0 0 0 188415 375113 700111 0 0 0 412106 0 346844 0 0 444529 430869 0 0 924567 0 254018 0 215119 0 177102 0 0 0 806140 174261 0 383620 0 166166 +AAAVNEYTVTFHPVSALDQTPIADAK MGYG000004735_01160 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1520@1|root,COG1520@2|Bacteria,1VR6X@1239|Firmicutes 1.0 1239|Firmicutes 1.0 M 1.0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_01160 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1005307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVNIVPN(Deamidated)STGAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_02459 0.011111111111111112 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 4078392 6494103 4130174 2941421 4627514 4546156 1853335 4790340 2406983 4953301 5067609 5290860 5944851 2702386 4532735 5695671 3368524 3087178 2756037 4819058 4704526 5627341 3045597 1625522 4939410 3072599 3543349 3033173 3352033 3794551 1252360 4480922 2745705 3107595 3299389 2279243 2609165 2908405 3297976 8795952 2537084 3082174 5021266 2816801 3954987 4393953 2983473 2524910 2947581 2797499 4172785 2271061 2251700 2022005 2619719 8662830 2521672 4088645 3287676 0 4651588 5506503 3127478 3013912 3906796 8083229 8002829 4745251 9237914 5101627 2923419 4356597 4241853 4004354 3811857 4408173 5078054 15976974 0 0 1387117 0 0 6136795 1876988 5598511 0 3861888 5263294 3996672 5488889 6590224 4715706 3099238 6585206 5742472 4739264 10937806 5526549 0 5094462 4377391 6923467 8254211 6346048 7213073 0 14610713 9243121 7893804 6973471 2160102 3393553 0 3156571 2584678 1396194 2277051 2250507 1008515 0 3061216 2193158 1167429 1535684 0 1969757 2976046 2761394 0 0 0 1521449 2042792 2376568 765194 0 616059 3004826 2505403 2764315 218532 0 2321630 0 3082115 1654505 1944409 2889703 2109856 3459695 0 8591826 12290223 18605059 8067591 3646916 8700802 15793812 8108862 9135244 15639228 11087124 14210846 3773821 16523885 13529719 9037757 12810145 1808461 11745509 3864791 13200929 7187278 2730532 7441138 12395535 9229354 12281103 3369326 11561920 5384874 10404292 8928709 19031053 12745210 7353617 11321856 12117215 11464127 +AAAVNIVPNS(Formyl[S](Ser->Asp)TGAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_02459 0.011111111111111112 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVNIVPNS(cGMP+RMP-loss)TAK MGYG000001781_01334 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Acutalibacter|s__Acutalibacter sp000432995|m__MGYG000001781 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,36DD0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001781_01334 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517657 0 0 0 0 0 0 0 1107882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVNIVPNST MGYG000002993_00787;MGYG000000262_01195;MGYG000004296_01958;MGYG000002517_01026;MGYG000001315_01699 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.6 186801|Clostridia 1.0 C 0.6 Psort location Cytoplasmic, score 0.6 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002993_00787 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 602137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1143564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVNIVPNST(Formyl[T](Thr->Glu)GAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_02459 0.011111111111111112 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAVNIVPNSTGAAK MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_02459 0.011111111111111112 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 37729595 59627023 33121903 33854829 36830164 43030360 22889784 42712067 26870756 41215756 50919554 49983722 53014521 20571197 30545102 49265807 42939631 15725789 17611874 37048554 49805825 0 22000777 21203276 37370850 24891835 37733561 19726878 36864672 39730434 17357939 32608944 27396549 23085312 32109528 25203661 30765416 31608747 48722513 109342209 32332872 39387484 54852950 26446238 50614088 40694332 34649165 34523068 41495960 31050659 47335748 24655933 26878796 22537924 33140998 0 27578907 47737930 40047785 19450771 62731234 57130554 32591402 33012965 41761898 101071898 87829694 52979727 121864068 53806285 34544076 49980487 49467634 51815438 35936739 52935103 42194807 0 39342877 42431672 15182921 40083022 29778391 53575272 18208234 39944590 36683977 56192342 35536566 27682130 45805354 60317906 48537361 39358583 60841011 48833746 43947009 0 70972302 33351180 37969711 42427206 58605500 90823352 56491963 0 33545902 0 88879198 0 41745365 25107039 33016075 44928388 12176569 2676636 2345257 4203335 3471926 1412348 3957157 10028690 6072146 1837771 1885439 9754355 5759568 6898032 10756549 1753594 2581803 0 2763660 3752853 11606445 882325 509948 282523 13513581 14006387 9112326 0 934434 5330597 347467 8490396 2110229 13069881 11972199 11452959 14221655 660409 142764778 0 0 0 47275553 0 0 134031362 127157770 216716494 144248141 205546689 51239932 229274423 190879904 134013141 171994880 23975288 0 0 178165815 114631010 46409834 141223266 176817115 129795155 168609594 52816606 169489869 89014993 143038809 138617348 281976655 0 113025565 174696021 153741909 147857634 +AAAVNIVPNSTGAAK(Cation_Na) MGYG000000280_02459;MGYG000000038_02185;MGYG000001607_01815;MGYG000003012_02911;MGYG000001710_00672;MGYG000001310_02090;MGYG000003821_01266;MGYG000000249_01352;MGYG000003695_01114;MGYG000001400_02195;MGYG000003828_01578;MGYG000000262_01195;MGYG000002234_00398;MGYG000000140_01181;MGYG000000369_00836;MGYG000001456.1_00715;MGYG000000080_03115;MGYG000002528_00367;MGYG000000223_00996;MGYG000004140_01100;MGYG000001711_02099;MGYG000002279_00557;MGYG000004799_00704;MGYG000002286_00420;MGYG000000164_00800;MGYG000000002_02120;MGYG000001748_01525;MGYG000004271_00554;MGYG000002194_02222;MGYG000002966_00075;MGYG000000100_02166;MGYG000000404_00344;MGYG000003552_01242;MGYG000003702_00925;MGYG000001652_01009;MGYG000002492_01379;MGYG000000127_04855;MGYG000000077_00219;MGYG000000252_01324;MGYG000000365_00999;MGYG000002993_00787;MGYG000000301_01012;MGYG000001199_01005;MGYG000002945_00682;MGYG000001186_01925;MGYG000000229_00395;MGYG000000312_01508;MGYG000004610_00503;MGYG000000204_00778;MGYG000002857_01020;MGYG000004288_00401;MGYG000004740_01468;MGYG000000045_02136;MGYG000002212_00259;MGYG000000495_01130;MGYG000004826_01307;MGYG000000974_00886;MGYG000000175_00767;MGYG000004296_01958;MGYG000004714_00143;MGYG000000213_00374;MGYG000000281_02732;MGYG000004519_00423;MGYG000002517_01026;MGYG000000142_01979;MGYG000000263_01341;MGYG000001697_00003;MGYG000000806_01930;MGYG000004707_01697;MGYG000000251_00555;MGYG000002992_00164;MGYG000000212_01474;MGYG000002974_01418;MGYG000000615_00488;MGYG000004785_01017;MGYG000000398_00286;MGYG000002278_02184;MGYG000000171_00850;MGYG000001683_01827;MGYG000001008_00728;MGYG000000271_03250;MGYG000001421_02311;MGYG000001338_02547;MGYG000001602_01805;MGYG000000133_02283;MGYG000002298_02410;MGYG000000153_00303;MGYG000001315_01699;MGYG000000489_00503;MGYG000001439_00571 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.4444444444444444 186801|Clostridia 0.9111111111111111 C 0.6222222222222222 Psort location Cytoplasmic, score 0.5111111111111111 gap 1.0 - 0.9666666666666667 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_02459 0.011111111111111112 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 647042 1362154 360003 0 0 835735 321567 268815 0 270894 0 0 0 0 284396 0 706810 0 245616 984035 1246746 1570133 0 272882 0 267316 0 0 384807 0 0 620999 312200 0 0 291531 542506 688011 1623762 3444373 1018152 0 0 451287 1037775 696010 0 608917 0 0 0 0 424390 0 727877 0 627169 1178874 863109 0 0 1025599 0 678319 0 0 1638663 0 0 951912 976171 0 0 1514356 727132 1631914 1786266 4088087 0 0 0 1447739 1007541 1770585 0 1522671 0 0 0 0 1281762 0 1395114 0 1818032 1612951 1385189 2808109 0 873255 0 718007 0 0 1828439 0 0 4210477 3023196 0 0 780797 1044857 1373743 372800 239995 746630 0 0 262903 406544 215323 0 244406 0 0 0 0 489684 0 309797 0 298071 449755 476903 475809 0 243600 0 638717 0 0 0 0 0 472393 498323 0 0 378463 608324 404837 4572278 5742860 5781466 0 0 3652079 4769561 3807192 0 5910343 0 0 0 0 6060620 0 3955039 0 4925055 2267113 5149178 4561196 0 1745646 0 1910417 0 0 5195867 0 0 5543844 4947207 0 0 2079916 2181302 4050095 +AAAVSLDIPLYR MGYG000002492_02565 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 - 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 - 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000002492_02565 1.0 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2690069 0 0 0 0 1272919 0 0 0 0 1834420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAYFLMAK MGYG000000042_01529;MGYG000001835_02138 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes,2FP8W@200643|Bacteroidia,4AKSY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01529 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1946917 0 0 0 0 2480882 0 0 0 0 1890166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478604 0 0 0 0 466842 0 0 0 0 448845 0 0 0 0 0 0 0 0 0 0 +AAAYGPMC(Carbamidomethyl)QGIAKPVNDLSR MGYG000000242_02893 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,2681I@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Phosphate acetyl/butaryl transferase 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000242_02893 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00625:pta; phosphate acetyltransferase [EC:2.3.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641387 0 0 0 0 1036814 0 0 0 0 1201171 0 0 0 0 0 0 0 0 0 0 +AAAYLGTVIGK MGYG000000201_02097;MGYG000000252_01803;MGYG000004733_00984;MGYG000004869_03336;MGYG000000301_00176;MGYG000000212_03063;MGYG000000171_01889;MGYG000000002_00866;MGYG000002966_02559;MGYG000000133_00061;MGYG000002298_00344;MGYG000000251_01815 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3XZZX@572511|Blautia 0.9166666666666666 186801|Clostridia 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_02097 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 532585 589441 1189724 392401 0 2630881 234829 607353 226947 687859 1385644 879852 736693 325505 844741 1012910 751641 1074777 475288 512322 591714 2774245 1002854 1317538 530431 508318 456678 804274 1816519 489811 1314783 506329 1148161 586639 513574 429066 387633 1272689 0 331300 340865 0 0 0 464683 0 0 486398 0 0 372802 0 0 320618 389407 287548 0 267962 370251 0 294626 0 329359 285036 283310 296515 1467250 214449 646813 388970 0 0 317485 293270 350222 434107 856467 622678 923686 557752 0 1264103 552666 879046 591405 811341 397611 998693 631059 615629 925695 921110 1158194 646035 856406 807712 653143 1863944 386922 959186 843863 793327 987248 540225 984364 822796 1512344 1006463 1254146 1093074 797599 575694 874239 992453 0 876247 0 172362 0 0 0 0 0 0 365710 0 578904 257403 438384 691608 291499 0 0 0 0 0 0 0 0 0 0 477357 2938396 221609 1403476 303730 0 0 0 0 208374 544543 7247541 7778802 5647784 8676392 0 3278910 10926021 7497803 4329735 8571335 5734271 5983074 4468903 11518732 7501554 5516083 5639311 218058 6272046 1690820 9605431 5408714 234426 5880109 6624012 5449532 8413451 708358 10360098 1457866 5154822 7151519 8002803 8855380 4851370 7162753 3838083 4154454 +AAAYLGTVIGKK MGYG000000201_02097;MGYG000004733_00984;MGYG000004869_03336;MGYG000000301_00176;MGYG000000212_03063;MGYG000000171_01889;MGYG000000002_00866;MGYG000000133_00061;MGYG000002966_02559;MGYG000002298_00344;MGYG000000251_01815 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3XZZX@572511|Blautia 0.9090909090909091 186801|Clostridia 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_02097 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 353234 609799 1134634 278908 0 2014333 77176 618592 286385 349239 890345 530636 680231 394396 556351 804930 557425 0 372336 0 427343 2108840 0 1145130 451705 452335 299527 0 1058783 0 1251887 484272 795892 226406 0 228527 301701 1049111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 621208 0 0 0 0 0 0 0 0 0 327419 477251 396459 171456 0 212684 97848 506101 0 272737 86712 276109 261773 119984 302548 433569 618558 0 272804 0 245265 999846 0 298936 159619 261576 350370 0 103780 0 608956 417599 355834 540703 0 0 209994 401953 0 549497 350791 0 0 94182 0 0 0 0 103780 0 197389 111551 0 194998 267495 0 0 0 0 335902 0 0 0 0 0 0 530482 0 481971 329068 141326 0 0 0 0 77020 3735871 4323782 4683117 6286982 0 2235308 6125013 2903065 2780021 6169163 4044625 4475865 3376161 6101993 4201888 3237002 4140593 0 3604992 0 6252843 0 0 4912913 3597169 2538473 5448415 0 5754407 0 3182507 4593325 6563540 3630129 0 3770566 2638940 2946787 +AAAYLGTVLGKK MGYG000000201_02097;MGYG000000301_00176;MGYG000000133_00061 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3XZZX@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 - 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_02097 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2858255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAYPGIEIVPLK MGYG000001306_03249;MGYG000000781_01397;MGYG000003693_02828 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4656@1|root,COG4656@2|Bacteria,4NIS7@976|Bacteroidetes,2FMAQ@200643|Bacteroidia,4AM9Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4_10,Fer4_17,Fer4_7,Fer4_8,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_03249 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03615:rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1552250 0 0 0 0 2185547 0 0 0 0 1480303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212036 0 0 0 0 103354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247237 0 0 0 0 135531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAAYSASAK MGYG000000022_02021;MGYG000002040_00989;MGYG000002274_00825;MGYG000002619_02367;MGYG000001300_02195;MGYG000003166_00778;MGYG000003899_00633;MGYG000000195_02114 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WIV7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_02021 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 0 1751630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2379769 1032685 1261585 1764540 0 0 2622715 0 0 0 2277135 3656089 0 0 0 0 0 0 0 0 0 0 0 3668303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5799343 1358486 6111918 3714904 0 0 4347478 0 0 0 5613039 4182012 0 0 0 0 0 0 0 0 0 0 0 1887269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 862219 0 448550 399486 0 0 0 0 0 0 1248097 3780831 0 0 0 0 0 0 0 0 0 0 0 1711773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1350454 928249 0 1540633 0 0 238373 0 0 0 1596684 1147416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295894 5638800 0 0 0 0 4283652 0 0 0 322019 571790 0 0 0 0 0 0 0 0 0 0 +AAAYVEIIC(Carbamidomethyl)K MGYG000002517_02724 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0119@1|root,COG2207@1|root,COG0119@2|Bacteria,COG2207@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) 1.0 leuA 1.0 - 1.0 2.3.3.13 1.0 ko:K01649 1.0 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 1.0 M00432 1.0 R01213 1.0 RC00004,RC00470,RC02754 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HMGL-like,HTH_18,LeuA_dimer 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02724 1.0 2-isopropylmalate synthase. isopropylmalate synthetase. Formerly EC 4.1.3.12. 3-methyl-2-oxobutanoate + acetyl-CoA + H2O = (2S)-2-isopropylmalate + CoA + H(+). 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K01649:leuA, IMS; 2-isopropylmalate synthase [EC:2.3.3.13] 1.0 none 1.0 413405 0 0 0 0 0 0 0 264527 0 0 0 0 430460 0 0 285064 0 0 433362 395149 0 0 0 0 398626 0 0 0 0 0 0 0 0 0 0 326074 0 432320 0 0 0 0 0 0 0 453586 0 0 0 0 397798 0 0 403228 0 0 296695 238512 0 0 0 0 375667 0 0 0 0 0 0 0 0 0 0 632206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1386313 0 0 0 0 0 0 0 1871015 0 0 0 0 1667951 0 0 1642362 0 0 1557255 1607317 0 0 0 0 810217 0 0 0 0 0 0 0 0 0 0 0 0 996791 0 0 0 0 0 0 0 570570 0 0 0 0 1103529 0 0 0 0 0 544260 809221 0 0 0 0 818597 0 0 0 0 0 0 0 0 0 0 0 0 +AAAYWHAK MGYG000002506_02716 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG2375@1|root,COG2375@2|Bacteria,1R4TD@1224|Proteobacteria,1RY01@1236|Gammaproteobacteria,3XMHN@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 P 1.0 ferric-chelate reductase (NADPH) activity 1.0 yqjH 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010045,GO:0016491,GO:0016722,GO:0016723,GO:0019725,GO:0030003,GO:0033212,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048037,GO:0048878,GO:0050660,GO:0050662,GO:0050801,GO:0050896,GO:0051716,GO:0052851,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071289,GO:0071949,GO:0097159,GO:0098771,GO:1901265,GO:1901363 1.0 1.16.1.9 1.0 ko:K07229 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_9,PadR,SIP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02716 1.0 ferric-chelate reductase (NADPH). NADPH:Fe(3+)-EDTA reductase. The enzyme, which is widespread among bacteria, catalyzes the reduction of ferric iron bound to a variety of iron chelators (siderophores), including ferric triscatecholates and ferric dicitrate, resulting in the release of ferrous iron.-!-The enzyme from the bacterium Escherichia coli has the highest efficiency with the hydrolyzed ferric enterobactin complex ferric N-(2,3-dihydroxybenzoyl)-L-serine. cf. EC 1.16.1.7 and EC 1.16.1.10. 2 a Fe(II)-siderophore + H(+) + NADP(+) = 2 a Fe(III)-siderophore + NADPH. 1.0 1.0 1.0 1.0 - 1.0 K07229:yqjH; ferric-chelate reductase (NADPH) [EC:1.16.1.9] 1.0 none 1.0 542832 0 199582 0 0 604892 0 645114 0 0 0 0 0 0 0 0 436925 0 710167 0 0 676804 0 790348 105324 201408 386198 0 300472 0 0 0 240675 471862 283804 0 370195 161242 143462 0 0 0 0 611127 0 247673 0 0 0 0 0 0 0 0 269362 0 0 0 0 729166 0 582069 0 0 33709 0 250247 0 0 0 672761 170271 208060 0 145866 443778 341741 0 67830 0 0 630560 0 280897 0 0 0 0 0 0 0 0 0 0 445534 0 0 311387 0 443653 193788 141982 154502 0 604637 0 0 0 65537 518986 357692 0 273544 74335 830540 0 607167 0 0 1259191 0 1167049 0 0 0 0 0 0 0 0 890347 0 525353 0 0 950760 0 635040 761184 730055 849971 0 604003 0 0 0 1173436 724938 1070828 0 903655 609141 0 0 0 0 0 0 0 38478 0 0 0 0 0 0 0 0 0 0 43154 0 0 0 0 85149 90124 72071 76349 0 15025 0 0 0 54578 47849 0 0 65948 0 +AAC(Carbamidomethyl)ADKFRK MGYG000000142_01590;MGYG000000171_01288 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG2407@1|root,COG2407@2|Bacteria,1TQ5Q@1239|Firmicutes,248V0@186801|Clostridia,3XZ8N@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01590 0.5 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01818:fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185226 0 0 0 0 51242 0 0 0 0 140349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405481 0 0 0 0 0 0 0 0 0 1173815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAC(Carbamidomethyl)AGEVDGEIVDLR MGYG000002492_02065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3WGVM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 - 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000002492_02065 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01868:TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3] 1.0 none 1.0 0 0 625090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1237958 0 0 0 0 1107714 0 0 0 0 1468186 0 0 0 0 396841 0 0 0 0 0 0 0 1166204 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364339 0 0 0 0 565164 0 0 0 0 728718 0 0 0 0 1265231 0 0 0 0 1106550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAC(Carbamidomethyl)AGEVDGEVVDLR MGYG000000204_01915;MGYG000000164_00182 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,25UXD@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 - 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000000204_01915 0.5 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01868:TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAC(Carbamidomethyl)AGEVN(Deamidated)GEVVDLR MGYG000000171_01863;MGYG000000212_03088;MGYG000004785_00534;MGYG000001338_01044;MGYG000000200_00587;MGYG000001602_01700;MGYG000002298_00403 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3XYSJ@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 10.00 1.0 thrS 1.0 - 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000000171_01863 0.14285714285714285 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01868:TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAC(Carbamidomethyl)AGEVNGEVVDLR MGYG000000171_01863;MGYG000000212_03088;MGYG000004785_00534;MGYG000001338_01044;MGYG000000200_00587;MGYG000001602_01700;MGYG000002298_00403 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3XYSJ@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 10.00 1.0 thrS 1.0 - 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000000171_01863 0.14285714285714285 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01868:TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3] 1.0 none 1.0 686039 1067004 809717 0 0 0 0 0 0 0 1092620 349356 0 0 0 796505 0 952438 0 0 0 0 485862 0 0 494412 0 819224 0 0 657103 838511 444932 0 0 0 425799 708522 349223 1108806 0 0 0 0 0 0 0 0 0 0 0 0 0 164827 0 793204 0 0 0 0 445814 0 0 184426 0 593354 0 0 1377231 453920 0 0 0 0 187236 199003 424448 1546513 733912 0 0 0 0 0 0 0 503053 1003573 0 0 0 568510 0 0 0 0 0 0 0 0 0 600388 0 632150 0 0 1002313 1257580 579681 0 0 0 573215 704438 394957 1430677 558975 0 0 0 0 0 0 0 642291 508095 0 0 0 612720 0 0 0 0 0 0 0 0 0 460579 0 645330 0 0 1261540 1065357 862158 0 0 0 410540 1002338 0 1002110 748787 0 0 0 0 0 0 0 585279 481065 0 0 0 466909 0 737031 0 0 0 0 634410 0 0 296897 0 518370 0 0 924402 680261 963449 0 0 0 429933 853431 +AAC(Carbamidomethyl)C(Carbamidomethyl)HC(Carbamidomethyl)SMC(Carbamidomethyl)SEVC(Carbamidomethyl)PR MGYG000000077_01493;MGYG000000262_00349 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,25URU@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 RnfC Barrel sandwich hybrid domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_01493 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 482696 283546 252299 0 0 0 310587 0 373164 278179 0 492438 0 390766 500697 313879 0 259472 0 0 448620 0 174270 326472 0 135195 0 446279 0 319185 246252 263735 0 0 0 0 0 502976 351836 0 362865 0 276257 751995 298640 0 275961 0 0 286499 126540 318082 0 277569 0 410794 437929 363869 201390 0 412268 460498 351032 377324 0 648658 0 262199 205729 0 406323 0 491932 241916 0 1033438 1155043 305003 1090297 0 1073170 0 782022 0 796216 795751 0 803015 710089 769996 845943 766052 0 1738209 1041590 942943 1658513 0 837129 994129 942812 1028830 0 539469 0 580665 1045548 515622 1008545 0 382770 619123 375207 340834 309555 0 0 0 531827 355766 0 0 528939 0 0 453271 320024 198136 344027 0 0 0 0 0 403543 0 192387 0 0 219620 0 0 0 0 0 0 0 0 0 0 0 941425 1637321 1472233 699651 0 835139 538477 723666 0 951538 1494158 0 1719893 649251 1028136 1781331 883802 0 1306417 1272495 571641 1304841 0 773272 811750 1038929 1217846 0 397788 0 1802368 1544067 1829139 1209264 0 990107 1382930 1277733 +AAC(Carbamidomethyl)DEFFKR MGYG000004797_02288;MGYG000002478_02020 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,4AKEY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_02288 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 442000 332906 0 201138 312941 0 0 0 434040 0 0 624432 0 285627 0 0 0 367370 323646 547394 0 0 0 284980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436141 365905 0 390659 452493 0 0 0 544878 0 0 465697 0 376617 0 0 0 306265 410186 301417 0 0 0 460918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375346 338222 0 132574 320888 0 0 0 300899 0 0 329665 0 435642 0 0 0 176099 314240 283373 0 0 0 295002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380156 360950 0 111144 495561 0 0 0 0 0 0 364716 0 642719 0 0 0 0 971001 0 0 0 0 153308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582035 424858 0 653348 457093 0 0 0 844671 0 0 669413 0 772582 0 0 0 511591 560367 445892 0 0 0 681588 0 0 0 0 0 0 0 0 0 0 +AAC(Carbamidomethyl)DEFFR MGYG000003693_02571 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,4AKEY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_02571 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460617 0 0 0 0 538676 0 0 0 0 417484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAC(Carbamidomethyl)DVYFEK MGYG000002438_01848 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,22WFC@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Domain of Unknown Function (DUF349) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01848 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 148825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 923764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1158444 0 0 0 0 0 0 0 0 +AAC(Carbamidomethyl)EALK MGYG000000002_01445 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A faecis|m__MGYG000000002 1.0 COG1653@1|root,COG1653@2|Bacteria,1TSGC@1239|Firmicutes,24A24@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000002_01445 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3424535 0 1152031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3582360 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3656410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 626087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723350 0 967100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAC(Carbamidomethyl)EDAIR MGYG000001410_00463 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__Sutterella wadsworthensis_A|m__MGYG000001410 1.0 COG0443@1|root,COG0443@2|Bacteria,1MVEN@1224|Proteobacteria,2VH14@28216|Betaproteobacteria,4PQEF@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001410_00463 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 842982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 862898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAC(Carbamidomethyl)EEFGM(Oxidation)K MGYG000002794_01352;MGYG000002720_01439;MGYG000002057_00766 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG1609@1|root,COG1609@2|Bacteria,1TSVS@1239|Firmicutes,24CU2@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 Protein of unknown function (DUF3798) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF3798 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_01352 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAC(Carbamidomethyl)EEFGMK MGYG000002794_01352;MGYG000002720_01439;MGYG000002057_00766 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG1609@1|root,COG1609@2|Bacteria,1TSVS@1239|Firmicutes,24CU2@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 Protein of unknown function (DUF3798) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF3798 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_01352 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 3683927 0 0 3690657 2413743 3486090 4760347 3867152 3874890 0 0 0 0 3749079 3646594 0 3043603 0 0 0 3019394 2398304 0 3291857 3278666 4337942 3365085 0 0 0 1967881 0 0 3323658 4214984 3346319 3814194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 186242 0 0 0 0 0 287842 0 274859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294641 0 0 0 0 0 0 0 0 0 0 0 0 0 142313 0 0 343159 0 0 0 0 0 0 0 0 0 208846 238404 0 314206 0 0 0 506671 0 0 0 584203 461307 0 0 0 0 0 0 0 301101 0 168263 207442 0 0 0 0 0 0 0 128564 0 0 0 0 0 0 340914 266583 0 0 0 0 0 301670 430116 0 164481 89813 172873 233579 0 0 0 0 0 0 114964 0 0 125705 0 +AAC(Carbamidomethyl)EEMAK MGYG000002478_04117;MGYG000000243_00095 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002478_04117 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 151411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAC(Carbamidomethyl)EPLLK MGYG000002272_00456;MGYG000004681_01722;MGYG000000573_00113;MGYG000001300_02210;MGYG000002040_00975;MGYG000003899_00619;MGYG000003166_00764;MGYG000002545_01135;MGYG000000195_02128;MGYG000000022_02035;MGYG000003921_00348;MGYG000002619_02381;MGYG000001157_01263;MGYG000001627_01317;MGYG000002610_01889;MGYG000000392_01456;MGYG000004732_00519;MGYG000000258_00286;MGYG000003937_00262;MGYG000002105_00236;MGYG000002641_00983;MGYG000002274_00840;MGYG000002224_01655 domain d__Bacteria 1.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3WJ9K@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome 1.0 rplV 1.0 - 1.0 - 1.0 ko:K02890 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L22 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002272_00456 0.043478260869565216 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02890:RP-L22, MRPL22, rplV; large subunit ribosomal protein L22 1.0 none 1.0 3307149 3704865 3442206 168919 2306014 3566255 0 0 0 0 2320233 186247 3678388 4868474 0 0 3030894 7678487 0 3566593 0 3437289 7275445 3262783 0 2570374 4700890 7013747 126347 2622258 2591443 0 3348463 0 5041980 3017239 4990623 3864455 4613710 3335165 3920015 4143212 1856257 2528819 0 0 0 0 2600810 4207387 2535086 3782564 0 0 3961654 4825586 0 4566656 0 2243361 7125593 2437052 4098487 3755217 3679963 5666771 693765 3576963 2886474 0 4228653 0 2403783 4179650 4502699 3208042 3097934 2682349 3028519 3505262 3106174 3260275 0 0 0 0 2803822 3101181 2857443 3076361 0 0 3264071 11392924 0 2647977 0 2945934 8296224 3369070 3193436 2747508 2437144 8608829 2193130 4211443 2660305 0 2368598 0 2239199 3084864 3340513 2552464 3207466 3557076 5377520 3365804 4199070 4918626 0 0 0 0 5037405 7321734 3829690 3347474 0 0 3132982 9368501 0 3715462 0 4346096 6013802 4428330 4244478 4388734 3767949 8846709 2949925 5118426 4885749 0 5462745 0 2439455 3647184 3598329 4718715 496098 898434 1579418 1085837 714173 896074 0 0 0 0 856498 2969321 925880 533627 0 0 927503 6590913 0 661648 0 657151 7769534 470198 765592 1077404 956037 5782738 1088116 488980 985428 0 1332756 0 1018894 564068 860169 1520863 +AAC(Carbamidomethyl)GNIIPSSTGAAK MGYG000003469_01436;MGYG000003542_01626 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003469_01436 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 583813 0 0 0 0 0 391092 0 0 0 0 0 0 0 0 0 0 475917 0 +AAC(Carbamidomethyl)LLTISDSFTSHK MGYG000002485_00105 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0813@1|root,COG0813@2|Bacteria,3789D@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 F 1.0 purine-nucleoside phosphorylase 1.0 deoD 1.0 - 1.0 2.4.2.1 1.0 ko:K03784 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_00105 1.0 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Nicotinate and nicotinamide metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K03784:deoD; purine-nucleoside phosphorylase [EC:2.4.2.1] 1.0 none 1.0 0 0 705993 0 0 0 0 0 0 0 0 837997 0 0 0 0 0 0 0 0 305506 0 0 0 0 0 0 0 0 0 0 0 300087 0 0 0 0 434699 0 0 621904 0 0 0 0 0 0 0 0 181608 0 0 0 0 0 0 0 0 1371341 0 0 0 0 0 0 0 0 0 0 0 522764 0 0 0 0 1158525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAC(Carbamidomethyl)QILEILLGE MGYG000002438_02292 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,4NFS0@976|Bacteroidetes,2FNWM@200643|Bacteroidia,22WFX@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 mutB 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02292 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 121376 0 0 0 0 0 0 0 0 0 0 0 132955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403440 0 0 0 0 0 0 93951 0 694824 0 0 0 140075 0 0 0 0 0 0 4314360 2797250 0 0 0 0 0 0 0 0 0 0 0 0 221645 0 0 0 287053 0 4616106 0 0 0 0 1146060 0 164446 0 0 0 265147 0 0 0 0 0 0 183407 177776 0 0 0 0 0 0 0 0 0 0 0 0 480783 0 0 0 126403 0 861896 0 0 0 0 287575 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563127 0 0 0 1842180 0 418150 0 0 0 0 0 0 3434999 0 0 0 5321644 0 0 0 0 0 0 3028309 3522927 0 0 0 0 0 0 0 0 0 0 0 0 2936361 0 0 0 8417067 0 3926479 0 0 0 0 719155 0 +AAC(Carbamidomethyl)WLLLSR MGYG000002478_00957 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,2FNRM@200643|Bacteroidia,4AKT2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00957 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 290501 560505 99611 498526 982561 457986 520833 382323 371156 0 116639 0 162658 0 219150 90856 422434 116006 378618 364184 291012 287258 114092 456242 0 441621 448982 418094 818491 420223 0 814934 271348 420073 106680 0 142229 285112 544614 176311 616314 677766 1486341 0 484695 398229 493340 0 542737 0 268813 0 621414 857698 442131 516316 0 285392 165494 103633 817707 0 0 668084 628283 559649 0 0 0 847436 0 294616 640301 0 0 398643 0 0 0 0 0 0 0 0 0 0 0 0 121229 0 0 71201 0 138496 156804 0 0 119220 0 0 0 0 0 0 0 0 0 0 0 175902 339020 0 0 0 90210 0 175100 0 184326 0 0 0 0 0 1032386 0 0 0 84801 0 0 862071 0 0 0 0 0 233811 0 0 265047 368573 0 0 0 191237 0 0 0 0 0 0 1018395 794771 1011676 1133363 1915368 1019195 772518 962200 816209 0 601571 0 626237 0 770989 751239 1051777 3033304 883651 1187197 687289 875222 2430817 870011 0 900094 917558 2371338 1400665 1053036 0 1364362 537074 862440 984214 0 891353 819184 +AAC(Carbamidomethyl)YLVR MGYG000003425_04484;MGYG000002025_01320;MGYG000003452_00823;MGYG000000099_02716;MGYG000001292_00841;MGYG000001300_00435 domain d__Bacteria 1.0 COG4716@1|root,COG4716@2|Bacteria,2GKZ8@201174|Actinobacteria,4CYZK@85004|Bifidobacteriales 0.3333333333333333 186801|Clostridia 0.5 S 1.0 MCRA family 0.6666666666666666 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003425_04484 0.16666666666666666 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 - 1.0 K10254:ohyA, sph; oleate hydratase [EC:4.2.1.53] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1633874 0 0 0 762884 0 0 0 1117924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1173693 0 0 0 0 0 0 0 0 0 1112586 1025150 0 623822 0 0 0 626523 0 0 0 709441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 566500 0 0 0 0 0 0 0 0 0 801157 811739 0 326869 0 0 0 605019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 583205 0 0 0 0 0 0 0 0 0 586208 548129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134219 0 0 +AAC(Cys->Ala)GNIIPSSTGAAK MGYG000003469_01436;MGYG000003542_01626 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003469_01436 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1645929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6550396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1071888 0 1095284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAC(Cys->Asp)PNTYIISSR MGYG000002794_01702 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp003487665|m__MGYG000002794 1.0 COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia,2N8Z1@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate-binding protein PnrA-like 1.0 - 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_01702 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07335:bmpA, bmpB, tmpC; basic membrane protein A and related proteins 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2994094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 580889 0 0 0 0 +AAD(Asp->Asn)EVGALIDK MGYG000001338_01847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,NAD_binding_7,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01847 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAD(Asp->Xle)AAQPK MGYG000001661_03158;MGYG000003681_01989 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,2FM1B@200643|Bacteroidia,4AM7E@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate 1.0 deoD 1.0 - 1.0 2.4.2.1 1.0 ko:K03783 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001661_03158 0.5 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Nicotinate and nicotinamide metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K03783:punA, PNP; purine-nucleoside phosphorylase [EC:2.4.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4607133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAD(Asp->Xle)LDAIHDTVHEMAR MGYG000004733_01319 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3WGYN@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_01319 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAAAAIGE(Glu->Lys)GLQAFC(Carbamidomethyl)IPGSVADHR MGYG000000245_00061;MGYG000000404_00348;MGYG000002517_01686;MGYG000002492_01963;MGYG000004055_00746 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 0.8 183925|Methanobacteria 0.8 F 0.8 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 0.8 purD 0.8 - 1.0 6.3.4.13 0.8 ko:K01945 0.8 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 0.8 M00048 0.8 R04144 0.8 RC00090,RC00166 0.8 ko00000,ko00001,ko00002,ko01000 0.8 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000245_00061 0.2 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 0.8 0.8 0.8 0.8 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 0.8 K01945:purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] 0.8 none 1.0 0 0 0 0 0 77591 0 0 0 0 0 0 0 0 0 0 0 0 119188 0 0 319893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8799893 0 0 0 0 0 0 0 0 0 0 0 0 19860601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1823383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAAAAIGEGLQAFC(Carbamidomethyl)IPGSVADHR MGYG000000245_00061;MGYG000000404_00348;MGYG000002517_01686;MGYG000002492_01963;MGYG000004055_00746 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 0.8 183925|Methanobacteria 0.8 F 0.8 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 0.8 purD 0.8 - 1.0 6.3.4.13 0.8 ko:K01945 0.8 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 0.8 M00048 0.8 R04144 0.8 RC00090,RC00166 0.8 ko00000,ko00001,ko00002,ko01000 0.8 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000245_00061 0.2 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 0.8 0.8 0.8 0.8 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 0.8 K01945:purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] 0.8 none 1.0 9387187 0 0 342225 994190 387080 551600 10265876 326992 639620 314886 13322968 0 401210 393332 0 285956 0 251203 0 0 4527903 0 905094 0 375764 359025 0 0 12692355 0 0 0 17603997 20690653 0 368000 0 213264 0 0 311432 4861656 2958467 286354 803308 758433 440028 7383297 1265252 0 879557 723505 0 1619184 0 938590 0 0 1537649 0 591960 0 159353 916870 0 0 1070876 0 0 0 955749 563913 0 371087 0 1343314 0 0 1801237 447104 592480 444471 4638132 8311175 529742 9885706 441264 0 306122 507109 0 2949267 0 304985 0 0 665194 0 766094 0 22661521 683869 0 0 163920 0 0 0 367728 135205 0 382835 0 20070071 0 0 15435846 21919714 16111015 19313203 54797110 53964470 9977597 10344772 11027593 0 51247310 38300166 0 26835646 0 23403603 0 0 729442 0 980581 0 18937550 39677070 0 0 12549642 0 0 0 22419226 23847481 0 29582551 0 4851213 0 0 3607056 19449426 10798868 16120452 3131034 39178207 18545173 69719233 20414270 0 8520228 52425434 0 0 0 26059087 0 0 0 0 52351115 0 17007500 74848734 0 0 23495529 0 0 0 30841085 72766664 0 100229935 0 +AADAAAAIGEGLQAFC(Carbamidomethyl)IPGSVADHRK MGYG000000245_00061;MGYG000000280_02029;MGYG000000136_01348;MGYG000000002_01850;MGYG000000404_00348;MGYG000002517_01686;MGYG000000018_02387;MGYG000002492_01963;MGYG000004055_00746 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 0.6666666666666666 183925|Methanobacteria 0.6666666666666666 F 0.6666666666666666 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 0.6666666666666666 purD 0.6666666666666666 - 1.0 6.3.4.13 0.6666666666666666 ko:K01945 0.6666666666666666 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 0.6666666666666666 M00048 0.6666666666666666 R04144 0.6666666666666666 RC00090,RC00166 0.6666666666666666 ko00000,ko00001,ko00002,ko01000 0.6666666666666666 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000245_00061 0.1111111111111111 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 0.6666666666666666 K01945:purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] 0.6666666666666666 none 1.0 1001342 664769 626948 1238175 657152 609824 727280 1170987 955038 1144446 1241157 951631 881144 845757 1274917 551303 956478 583494 1098286 807313 977899 815321 630612 1126855 984176 1055372 2032355 1203330 0 1362029 0 631253 565908 0 0 1216199 1920289 461777 100599 47169 165944 182865 246708 42269 197716 173298 32688 120513 191620 46549 559164 230896 383979 663396 519815 813908 84748 145062 575627 94493 232508 250442 437527 149303 254001 767021 0 1898855 0 407088 1415117 0 0 727896 440962 187543 947080 318039 308904 94859 1812565 2352936 3025483 0 4996762 5079863 2662107 0 3141219 1139196 0 4222573 179055 120494 2860581 2314321 1529091 554457 282500 0 4478899 5071731 2995839 2174649 0 0 0 3409465 9878322 0 0 0 0 8770667 1991156 0 2656966 12143487 6587207 0 1656313 4358788 4124277 5711309 4556413 1761272 3944979 5286631 6067453 0 6204923 0 8557546 5886060 17025032 3143412 0 0 18158786 0 6765437 0 0 9176856 0 6408955 0 0 0 13199157 17448081 178962 4431048 13627303 0 0 5068203 5987157 8085688 5740639 16875778 12491112 22587608 9709397 2999492 15981390 18863333 5643954 7890746 7978835 12659351 5766150 13556805 17722458 0 17717931 25897455 0 25356322 0 0 7799644 0 402422 9818178 0 0 7803267 19805986 12232727 +AADAAAAIGEGLQAFC(Carbamidomethyl)IPGSVADTR MGYG000002025_00960;MGYG000001619_00078;MGYG000000142_02731;MGYG000000133_00506;MGYG000001338_01296;MGYG000001970_01269;MGYG000000212_00326;MGYG000000301_00647 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.625 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.87 0.625 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002025_00960 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6159000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4077568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155668 0 0 0 0 0 0 0 0 0 0 359209 383686 0 0 0 0 430060 0 0 4793957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93286 0 0 0 0 0 0 0 855990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224004 99675 0 0 0 0 0 0 0 28893726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30132321 0 0 0 0 0 0 0 0 0 0 32977095 85756023 0 0 0 0 18104448 +AADAAAAIGEGLQAFC(Carbamidomethyl)IPGSVADTRK MGYG000001619_00078;MGYG000000142_02731;MGYG000000133_00506;MGYG000001338_01296;MGYG000000301_00647 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.6 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.87 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001619_00078 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3782281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24895995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAAQPK MGYG000001661_03158;MGYG000003681_01989 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0005@1|root,COG0005@2|Bacteria,4NE4J@976|Bacteroidetes,2FM1B@200643|Bacteroidia,4AM7E@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate 1.0 deoD 1.0 - 1.0 2.4.2.1 1.0 ko:K03783 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001661_03158 0.5 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Nicotinate and nicotinamide metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K03783:punA, PNP; purine-nucleoside phosphorylase [EC:2.4.2.1] 1.0 none 1.0 167127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217440 0 0 0 0 0 406923 0 0 0 0 0 0 0 0 0 0 112804 0 225227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297034 0 0 0 0 0 265654 0 0 0 0 0 0 0 0 0 0 454762 0 262468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208701 0 0 0 0 0 327053 0 0 0 0 0 0 0 0 0 0 171935 0 171684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355654 0 0 0 0 0 83757 0 0 0 0 0 0 0 0 0 0 171419 0 193243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 293367 0 0 0 0 0 243730 0 0 0 0 0 0 0 0 0 0 272892 0 +AADAASYSGAEGDTADGAELTGWSGESR MGYG000002517_02514 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system 1.0 metN 1.0 - 1.0 - 1.0 ko:K02071 1.0 ko02010,map02010 1.0 M00238 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.24 1.0 - 1.0 - 1.0 ABC_tran,NIL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02514 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K02071:metN; D-methionine transport system ATP-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 762225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADADDEKTQSFVTK MGYG000002517_00614 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 PFAM Extracellular ligand-binding receptor 1.0 braC 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00614 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 1.0 K01999:livK; branched-chain amino acid transport system substrate-binding protein 1.0 none 1.0 239838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273966 403621 0 0 0 0 0 0 0 0 0 0 113094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2629056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3659707 3236542 0 0 0 0 0 0 0 0 2722667 0 3395543 0 438340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 523492 704201 0 0 0 0 0 0 0 0 234370 0 174800 0 +AADAETVDR MGYG000002494_01389 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,3XNR8@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 L-aspartate:2-oxoglutarate aminotransferase activity 1.0 aspC 1.0 GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.0 2.6.1.1,2.6.1.57 1.0 ko:K00813,ko:K00832 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 M00024,M00025,M00034,M00040 1.0 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 iPC815.YPO1410,iSFxv_1172.SFxv_1000 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01389 1.0 aspartate transaminase. | aromatic-amino-acid transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. | L-methionine can also act as donor, more slowly.-!-Oxaloacetate can act as acceptor.-!-Controlled proteolysis converts the enzyme to EC 2.6.1.1. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. | 2-oxoglutarate + an aromatic L-alpha-amino acid = an aromatic oxo-acid + L-glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00813:aspC; aspartate aminotransferase [EC:2.6.1.1]|K00832:tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1108520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1007429 0 0 0 0 721843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAEVENK MGYG000000089_01706 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000089_01706 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2293901 0 0 0 0 2624385 0 0 0 0 2346951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAFNTILENAR MGYG000000133_01741 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 2E3QR@1|root,32YNK@2|Bacteria,1VENX@1239|Firmicutes,24QVR@186801|Clostridia,3Y0KX@572511|Blautia 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1292 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01741 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 372357 0 270743 0 0 472058 0 0 394204 564839 0 0 247166 233054 887278 0 0 0 0 0 647036 411028 0 319230 491261 766815 0 0 464001 0 399810 552239 370466 0 367491 439802 695740 417496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134025 0 0 0 0 0 290847 0 0 0 0 0 0 175658 234964 0 163683 0 0 0 0 222923 449436 262197 177420 0 0 232446 510140 0 0 0 0 0 293466 215373 0 0 330413 0 0 0 346061 0 181689 422662 217585 0 325323 277246 279047 0 317705 0 230304 0 0 238646 0 430721 264706 427195 0 0 157777 497601 647600 0 0 0 0 0 0 0 0 276605 516344 462965 0 0 273281 0 256663 0 266587 0 323848 328312 108769 308041 1504984 0 1267808 0 0 677661 0 1564364 1011872 1940462 1637812 0 1526996 3162476 1176716 0 0 0 0 0 1665210 1071115 0 984477 1603878 1360275 0 0 2431505 0 1473424 2018111 2076948 0 1547621 1541072 981418 1163267 +AADAGSLEGK MGYG000000243_00992;MGYG000002478_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,4NFEB@976|Bacteroidetes,2FMPN@200643|Bacteroidia,4AMY0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 electron transport complex, RnfABCDGE type, B subunit 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_4,Fer4_6,Fer4_7,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00992 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03616:rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1830072 837149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 954676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 917420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAGSLEGKLC(Carbamidomethyl)PVGGAPVM(Oxidation)EK MGYG000000243_00992;MGYG000002478_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,4NFEB@976|Bacteroidetes,2FMPN@200643|Bacteroidia,4AMY0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 electron transport complex, RnfABCDGE type, B subunit 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_4,Fer4_6,Fer4_7,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00992 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03616:rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAGVANIK MGYG000001400_00237 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Erysipelatoclostridium|s__Erysipelatoclostridium ramosum|m__MGYG000001400 1.0 COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 family 4 1.0 - 1.0 - 1.0 3.2.1.86 1.0 ko:K01222 1.0 ko00010,ko00500,map00010,map00500 1.0 - 1.0 R00839,R05133,R05134 1.0 RC00049,RC00171,RC00714 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GT4 1.0 - 1.0 Glyco_hydro_4,Glyco_hydro_4C 1.0 3.2.1.86 1.0 GH4 1.0 GH4 1.0 GH4 1.0 MGYG000001400_00237 1.0 6-phospho-beta-glucosidase. phosphocellobiase. Also hydrolyzes several other phospho-beta-D-glucosides, but not their non-phosphorylated forms. 6-phospho-beta-D-glucosyl-(1->4)-D-glucose + H2O = D-glucose + D-glucose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Starch and sucrose metabolism 1.0 K01222:E3.2.1.86A, celF; 6-phospho-beta-glucosidase [EC:3.2.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2415736 0 3780165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 829672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAGVTPK MGYG000001300_02006;MGYG000003166_01216 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3WGEI@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation 1.0 metG 1.0 - 1.0 6.1.1.10 1.0 ko:K01874 1.0 ko00450,ko00970,map00450,map00970 1.0 M00359,M00360 1.0 R03659,R04773 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,tRNA-synt_1g,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 GH84 1.0 MGYG000001300_02006 0.5 methionine--tRNA ligase. MetRS. In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9. ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met). 1.0 1.0 1.0 1.0 Selenocompound metabolism|Aminoacyl-tRNA biosynthesis 1.0 K01874:MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1570400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAIQNAPEVK MGYG000002478_01138 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG3883@1|root,COG1196@2|Bacteria,COG3883@2|Bacteria,4P07U@976|Bacteroidetes,2FN9Y@200643|Bacteroidia,4APBT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 nuclear chromosome segregation 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Collagen,DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01138 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1340056 0 1274611 1770351 1143412 0 0 0 0 0 1049018 2686733 0 0 1912996 0 1650787 0 0 0 1058438 1805589 1123306 0 0 0 1450919 1095440 0 0 0 0 0 2091792 1480723 0 0 0 0 0 2294849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAKEPAVK MGYG000000013_00619 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp902362375|m__MGYG000000013 1.0 COG1449@1|root,COG1449@2|Bacteria,4NFXW@976|Bacteroidetes,2FMRY@200643|Bacteroidia,4AMCU@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glycosyl hydrolase 57 family 1.0 amyA 1.0 - 1.0 3.2.1.1 1.0 ko:K07405 1.0 ko00500,ko01100,map00500,map01100 1.0 - 1.0 R02108,R02112,R11262 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH57 1.0 - 1.0 Glyco_hydro_57 1.0 - 1.0 GH57 1.0 GH57 1.0 GH57 1.0 MGYG000000013_00619 1.0 alpha-amylase. glycogenase. Acts on starch, glycogen and related polysaccharides and oligosaccharides in a random manner; reducing groups are liberated in the alpha-configuration.-!-The term 'alpha' relates to the initial anomeric configuration of the free sugar group released and not to the configuration of the linkage hydrolyzed. Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units. 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Metabolic pathways 1.0 K07405:E3.2.1.1A; alpha-amylase [EC:3.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 530881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADALAK MGYG000002293_00140;MGYG000001056_00145;MGYG000001770_02072;MGYG000003697_01831 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00140 0.25 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02110:ATPF0C, atpE; F-type H+-transporting ATPase subunit c 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 346658 0 0 0 0 229195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 279930 0 0 0 0 0 0 0 0 0 0 0 363538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363862 0 0 0 0 0 0 0 0 0 0 0 751988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1091088 0 0 0 0 0 0 1128412 0 0 0 0 2806105 0 0 0 0 1029528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442975 0 0 0 0 0 0 231530 0 0 0 0 0 0 0 0 0 355618 0 0 0 0 0 0 0 0 0 0 +AADALRLPDWDAK MGYG000002506_04122;MGYG000002494_02896 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0488@1|root,COG0488@2|Bacteria,1MU37@1224|Proteobacteria,1RPWS@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 S 1.0 abc transporter atp-binding protein 1.0 yjjK 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 1.0 3.6.3.25 1.0 ko:K06020 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ABC_tran,ABC_tran_Xtn 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04122 0.5 ABC-type sulfate transporter. sulfate-transporting ATPase. An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins.-!-The enzyme from Escherichia coli can interact with either of two periplasmic binding proteins and mediates the high affinity uptake of sulfate and thiosulfate.-!-May also be involved in the uptake of selenite, selenate and possibly molybdate.-!-Does not undergo phosphorylation during the transport.-!-Formerly EC 3.6.3.25. ATP + H2O + sulfate(out) = ADP + H(+) + phosphate + sulfate(in). 1.0 1.0 1.0 1.0 - 1.0 K06020:ettA; energy-dependent translational throttle protein EttA 1.0 none 1.0 0 0 0 0 0 189199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378376 0 453212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 810621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1113047 0 866129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479885 0 574809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAMVK MGYG000000262_00362 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,25WKA@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_00362 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1071089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1414995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAPSGNVITKK MGYG000002517_00472 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00472 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3728727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAVGEDM(Oxidation)SK MGYG000000022_01831 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000022_01831 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179764 0 0 0 0 234065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388378 0 0 0 0 580322 0 0 0 0 693173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444494 0 0 0 0 188821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADAVGEDMSK MGYG000000022_01831 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000022_01831 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194017 0 0 0 0 0 0 0 0 0 142565 298658 0 452199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1234948 0 0 0 0 2580913 0 0 0 0 1708702 485065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5725554 0 0 0 0 4522697 0 0 0 0 4159233 902800 0 1106956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4160379 0 0 0 0 3189908 0 0 0 0 2453821 177752 0 0 0 0 0 0 0 0 0 +AADD(Cation_Fe[II])AAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 932168 644771 0 985419 394142 643358 0 368815 680280 548608 0 0 0 0 510766 0 654951 0 332430 681053 0 562983 0 497197 569931 699998 685468 0 0 0 247874 0 0 1334997 759822 0 979168 0 210595 182821 0 0 444854 94702 0 0 313655 98892 0 0 0 0 150956 0 170593 0 0 0 0 0 0 0 0 132419 0 0 0 0 156058 0 0 205539 143543 0 192788 0 106355 0 0 0 551562 157677 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444826 0 0 0 0 0 0 0 2944179 1009265 0 2992823 1598566 1121153 0 4409487 3736268 1826711 0 0 0 0 4320687 0 2028503 0 3335897 2838660 0 452253 0 218617 5102540 5044628 3115165 0 0 0 1007244 0 0 4561785 3924289 0 4288232 0 3066296 2127411 0 1207623 4641372 3257701 0 2026055 2763325 2776062 0 0 0 0 3768581 0 3204104 0 2408606 3233308 0 3145144 0 1565675 1713660 1221068 1168100 0 0 0 2264239 0 0 2679084 1237420 0 2244216 0 +AADD(Cation_Na)AAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4095284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDA(Ala->Gly)AGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLAISEK MGYG000001777_01359;MGYG000003422_01458;MGYG000000362_01735;MGYG000003422_01457;MGYG000000217_00038;MGYG000002934_00200;MGYG000001814_01561;MGYG000001514_01163 domain d__Bacteria 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia,27IQW@186928|unclassified Lachnospiraceae 0.375 186801|Clostridia 0.75 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 0.625 - 0.75 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001777_01359 0.125 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 6476154 5672430 5063094 6735068 0 5894585 8408148 6817048 0 0 0 0 6002811 6779870 0 5437039 0 13092774 0 5740380 0 4353205 15823285 6280746 4506275 0 6378571 14442163 0 0 0 6236745 5782611 0 0 0 0 4548977 281752 0 0 253025 0 0 0 275335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305950 586519 0 0 0 0 0 129306 0 0 0 341190 0 0 0 374183 0 0 0 0 0 0 0 0 0 486790 170179 0 569833 0 347506 0 0 0 0 463769 0 0 178772 0 0 0 0 0 0 0 0 0 0 0 0 542741 217377 1314599 0 0 760126 506959 221046 0 0 0 0 825596 0 0 863739 0 1615691 0 0 0 979676 2339884 912126 519114 490682 559160 916601 0 0 0 635132 831862 0 0 0 421467 965336 0 0 0 0 0 331554 0 0 0 0 0 0 876714 0 0 497230 0 641181 0 0 0 0 497355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLS(Deoxy[S](Ser->Ala)ISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001777_01322 0.022727272727272728 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 6598470 6217756 0 0 0 0 5450928 0 0 0 0 0 6029909 0 0 0 0 0 0 0 0 0 0 0 0 6892989 0 6928855 6546811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLS(Formyl[S](Ser->Asp)ISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001777_01322 0.022727272727272728 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLS(Methyl[S](Ser->Thr)ISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001777_01322 0.022727272727272728 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14636704 9868983 0 0 0 10832275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8615587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1512592 0 0 0 0 0 0 0 0 0 0 2656517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 28343328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLSIS(Formyl[S](Ser->Asp)EK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001777_01322 0.022727272727272728 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLSISEK MGYG000001777_01322;MGYG000002580_01396;MGYG000000076_00961;MGYG000004039_00624;MGYG000002580_01470;MGYG000001660_01820;MGYG000004317_00093;MGYG000002552_01183;MGYG000001637_00106;MGYG000001637_00105;MGYG000000325_01732;MGYG000002247_01324;MGYG000002141_00417;MGYG000003273_00999;MGYG000000489_01708;MGYG000000154_02141;MGYG000002552_01346;MGYG000002492_02952;MGYG000001141_00820;MGYG000000217_01135;MGYG000001141_01878;MGYG000000398_01070;MGYG000000078_00812;MGYG000002670_01665;MGYG000000489_00253;MGYG000003425_02442;MGYG000002670_01663;MGYG000000187_02828;MGYG000004697_01572;MGYG000003215_00935;MGYG000000387_01535;MGYG000002247_02078;MGYG000002559_00694;MGYG000004431_00807;MGYG000000562_01318;MGYG000000562_01835;MGYG000004431_02556;MGYG000000280_01150;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000002580_00507;MGYG000004414_00337;MGYG000000356_01332 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.9545454545454546 - 0.9772727272727273 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 0.9318181818181818 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001777_01322 0.022727272727272728 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 19405073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 622744 0 0 2720961 0 0 0 380025 2708881 3123282 0 1818237 539306 0 497192 1166892 2539207 1514021 0 0 0 1946516 587898 0 385497 1062024 625350 0 0 0 0 1077656 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14521803 0 0 4332144 0 1258082 854620 0 3825103 0 0 0 0 0 0 0 0 1011831 0 3917193 2944119 3578847 3264183 2890367 3510609 3658622 4147376 3982552 4499850 3353904 4239804 2843737 3184400 4100187 2574132 3193457 12914156 3071399 2812835 3597497 3008637 16546976 2820252 4198327 4280180 3766749 0 3322140 3817743 3226420 3925908 3031279 0 3881256 0 3899165 3463835 1048366 609666 2048895 1253343 2374685 897263 736871 840026 159849 0 846460 1478946 537556 584981 0 522687 0 1633697 798079 0 4054688 1217250 1433234 797242 863533 1001498 786450 1386198 810412 0 0 1055485 1162012 0 764550 782209 0 1972976 +AADDAAGLSISEKM(Oxidation)R MGYG000004317_00093;MGYG000000562_01318;MGYG000000562_01835;MGYG000001637_00105;MGYG000000187_02828;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000000154_02141;MGYG000003215_00935;MGYG000004414_00337 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.8181818181818182 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004317_00093 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLSISEKMR MGYG000004317_00093;MGYG000000562_01318;MGYG000000562_01835;MGYG000001637_00105;MGYG000000187_02828;MGYG000000245_00974;MGYG000000271_01499;MGYG000000187_02576;MGYG000000154_02141;MGYG000003215_00935;MGYG000004414_00337 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.36363636363636365 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 0.8181818181818182 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004317_00093 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLT(Formyl[T](Thr->Glu)ISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLT(Thr->Ser)ISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9607584 0 0 0 0 0 4760437 0 3149519 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLTIS(Formyl[S](Ser->Asp)EK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLTISE(Cation_Na)K MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 846536 0 0 474359 478037 0 349013 288581 417653 396642 0 0 0 0 402177 0 841354 0 453739 723842 0 0 0 0 484056 437917 547717 0 0 0 0 0 0 1232272 761025 260641 1159746 387375 288158 0 1031427 177158 0 0 0 0 0 230396 0 0 0 0 351399 0 0 0 0 0 0 0 0 0 354718 179704 0 0 0 0 0 0 1016333 0 0 566420 0 1099335 475564 0 730651 492533 419715 0 0 322042 442555 0 0 0 0 0 0 0 0 0 403244 0 0 0 0 0 0 0 0 0 0 0 0 0 498783 0 551178 0 0 681244 0 0 1377854 0 2350725 0 2445630 5572764 4312118 2373538 0 0 0 0 5072367 0 2908787 0 3684334 3689588 0 0 0 0 8185556 7586126 4079273 0 0 0 0 0 912290 6132163 4644392 4705181 0 1014578 3063148 0 2179839 1350653 4042734 0 1564545 1845001 2812513 2905008 0 0 0 0 3632976 0 3048947 0 0 3176495 0 0 0 0 1165447 1158483 1117360 0 0 0 0 0 817039 3221529 1009030 971245 2285454 3302703 +AADDAAGLTISEK MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 53126657 34630766 24247668 83426857 28813555 40674025 59489068 40522948 56082677 45782925 67626459 67363413 40324167 49122146 49541010 36050736 60455373 19740710 37643204 43669699 55295460 35203746 24812607 50275783 49741131 55127757 58356908 22286573 48076263 86471129 24956877 28079102 26241552 81892369 41294159 44762841 57697175 17873719 0 0 49005622 12588198 49999827 0 9584885 12256794 14481743 13277388 58469790 17752635 23410369 12517285 14774766 24688994 12828454 29913607 10010980 8839694 11291873 0 46619819 8277052 12278506 13228202 10896136 36478366 3638888 14643905 18943630 27346653 50845587 12658123 10472837 10463196 12300382 66738060 458730 2618110 41055060 273342 31583672 5881865 4925311 1843502 4181825 3214094 35883403 20667422 14142681 3411465 120256 14838590 3915922 3898195 89765 265342 3128923 190311 3468709 6100397 314661 2301084 789275 2969147 2497311 9770735 27098104 6012220 32093057 668765 296139 4355462 1157262 38780378 269736598 67427994 82976242 238332764 131460588 92701041 169576721 400616880 310412412 146699105 110079036 230563716 86631446 333877395 374030912 95037194 214465654 22759006 240587262 241446309 252787754 29369590 31885314 0 380907501 420408938 257253336 18809355 68790321 233502900 65863836 110148307 73713306 390212522 345337044 333111730 400530591 57748248 163879913 101611870 146604747 68808721 225587619 222816042 110437349 116462726 181580481 213512805 148201696 0 191888780 112865977 211098614 134675319 182715484 9243904 169445118 212111563 101752100 151294864 8762957 176095061 170956177 169140022 130963058 9001601 39150595 193129708 0 68154420 88630338 175979009 135363950 155785456 292824148 173627747 +AADDAAGLTISEK(Carbamidomethyl[K](Gly) MGYG000000997_01685;MGYG000000136_01850;MGYG000003694_02093;MGYG000000489_01309;MGYG000000398_01963;MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002492_03078;MGYG000003694_00680;MGYG000001186_01405;MGYG000002517_00135;MGYG000000997_00092 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.7857142857142857 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_01685 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLTISEKM MGYG000000489_01309;MGYG000001637_00814;MGYG000002492_03078;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.75 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000489_01309 0.25 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 495869 0 0 0 0 0 0 505721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477465 0 0 0 0 463890 0 267672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3791753 0 0 0 1906316 0 2635519 8226203 5203467 0 0 0 0 0 8670406 0 3759155 0 0 0 0 0 0 0 4796971 5353395 4039538 0 0 3698864 0 0 0 6104251 6061887 4199280 6782436 0 0 0 0 0 0 0 284437 0 0 0 0 0 0 0 0 0 148822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265316 0 +AADDAAGLTISEKM(Oxidation)R MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.8 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01770 0.2 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDAAGLTISEKMR MGYG000004271_01770;MGYG000004271_00134;MGYG000001637_00814;MGYG000000271_03698;MGYG000002517_00135 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1344@1|root,COG1344@2|Bacteria,1TP1K@1239|Firmicutes,247JQ@186801|Clostridia 0.8 186801|Clostridia 1.0 N 1.0 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella 1.0 - 1.0 - 1.0 - 1.0 ko:K02406 1.0 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 Flagellin_C,Flagellin_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01770 0.2 - - - - 1.0 1.0 1.0 1.0 Two-component system|Flagellar assembly|NOD-like receptor signaling pathway|Plant-pathogen interaction|Salmonella infection|Legionellosis 1.0 K02406:fliC, hag; flagellin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDNHYVAYN(Deamidated)GYVAGR MGYG000001489_02354 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides goldsteinii|m__MGYG000001489 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001489_02354 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1326854 0 0 0 977031 0 0 0 736105 550569 0 180757 0 0 367039 0 0 0 0 576628 0 0 0 0 320407 608065 0 0 472178 686873 0 796303 0 0 0 0 1505262 0 741108 0 0 0 701314 0 0 0 1160148 416598 0 612648 0 0 489162 589890 0 0 0 508100 0 0 0 0 0 0 0 0 417760 389134 0 968127 0 0 0 0 730375 0 940503 0 0 0 872319 0 0 0 862214 696028 0 377324 0 0 430388 534519 0 0 0 431013 0 0 0 0 583220 731901 0 0 760096 813767 0 485403 0 0 0 0 869082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2005783 0 0 0 2641215 0 0 0 1554437 1023626 0 883434 0 0 767817 2243443 0 0 0 2334845 0 0 0 0 992271 1081984 0 0 1009487 874059 0 1016302 0 0 0 0 1099808 0 +AADDNHYVAYNGYVAGR MGYG000001489_02354 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides goldsteinii|m__MGYG000001489 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001489_02354 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572049 489695 429912 0 691498 652184 463926 683598 642516 890298 0 0 1153311 0 496984 715870 648105 0 732830 813095 0 797560 0 978148 606219 638870 0 0 841884 695916 700077 891271 426460 959715 0 0 678229 615964 +AADDPSMHSSQNEQDSR MGYG000000013_02894;MGYG000003922_02595;MGYG000000003_01690;MGYG000000236_04031;MGYG000000196_04786;MGYG000001346_02973;MGYG000004830_00176;MGYG000002549_01331;MGYG000004899_00047;MGYG000001313_02737;MGYG000000243_02436;MGYG000003367_02060;MGYG000001666_01147;MGYG000001345_02148 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG4231@1|root,COG4231@2|Bacteria,4NJM1@976|Bacteroidetes,2FMYS@200643|Bacteroidia,4AN7N@815|Bacteroidaceae 0.7857142857142857 976|Bacteroidetes 1.0 C 1.0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates 1.0 iorA 1.0 - 1.0 1.2.7.8 1.0 ko:K00179 1.0 - 1.0 - 1.0 - 1.0 - 1.0 br01601,ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_02894 0.07142857142857142 indolepyruvate ferredoxin oxidoreductase. IOR. Preferentially utilizes the transaminated forms of aromatic amino acids and can use phenylpyruvate and 4-hydroxyphenylpyruvate as substrates.-!-This enzyme, which is found in archaea, is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = (indol-3- yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K00179:iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1046173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 997468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 782697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 426675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDQNVAISAR MGYG000002298_00329 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp000436615|m__MGYG000002298 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_00329 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 1376110 0 0 0 0 0 0 0 0 0 0 0 0 0 774357 0 1037695 0 481994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102428 0 215352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392771 0 0 0 0 0 0 0 0 0 0 0 0 0 220178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADDQNVVIAAR MGYG000004733_00969 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_00969 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 537662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1132323 0 462391 0 0 0 0 0 0 770614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADEAAAPAVVEEGGLHK MGYG000001364_01116;MGYG000003693_02590 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001364_01116 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3367172 0 0 0 0 5320503 0 0 0 0 4211470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 677073 0 0 0 0 559146 0 0 0 0 516295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADEADNNTLSPIYLK MGYG000003681_00782 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,4ANQH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_00782 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 324419 0 0 0 445859 0 342813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334043 0 0 0 415934 0 0 0 0 0 0 0 422235 0 0 0 1635317 0 1381328 0 0 0 0 0 0 0 0 0 1247700 0 0 0 0 0 0 0 0 0 1234155 0 0 0 846309 0 975977 0 0 0 0 0 796813 0 0 0 636212 0 790809 0 0 0 0 0 0 0 0 0 434049 0 0 0 0 0 0 0 0 0 779183 0 0 0 641767 0 587743 0 0 0 0 0 329652 0 0 0 491355 0 365002 0 0 0 0 0 0 0 0 0 345412 0 0 0 0 0 0 0 0 0 240029 0 0 0 303456 0 431351 0 0 0 0 0 476972 0 0 0 607514 0 449142 0 0 0 0 0 0 0 0 0 598349 0 0 0 0 0 0 0 0 0 752930 0 0 0 732577 0 474091 0 0 +AADEADNTTLSPIYLK MGYG000001313_02385 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,4ANQH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_02385 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378163 0 0 0 0 0 0 0 0 0 0 0 0 0 0 473776 0 0 0 0 0 0 0 0 0 0 0 0 0 523544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364948 439291 0 246463 0 0 0 0 0 0 0 0 0 0 0 0 0 1328046 0 0 0 0 0 0 0 0 954945 0 2004302 0 0 0 0 1722720 0 0 0 0 1473955 1127224 0 965413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756167 0 0 0 0 641175 435633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338815 0 0 0 0 0 0 0 0 268047 0 0 0 0 0 0 0 0 0 0 0 376210 335000 0 369026 0 0 0 0 0 0 0 +AADEC(Carbamidomethyl)GEDIVSQPDISVTQIEK MGYG000004735_02622 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_02622 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 761019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1896945 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADEC(Carbamidomethyl)GLELVSQPK MGYG000000187_01475 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG0056@1|root,COG0056@2|Bacteria,4NFZW@976|Bacteroidetes,2FM4H@200643|Bacteroidia,4AKBP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 - 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000187_01475 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1253178 0 0 0 0 1177231 0 0 0 0 691516 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 602392 0 0 0 0 643949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADEETLAR MGYG000002026_01136 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__HGM13010|s__HGM13010 sp900754965|m__MGYG000002026 1.0 COG1638@1|root,COG1638@2|Bacteria,1UCYF@1239|Firmicutes,24BR8@186801|Clostridia,2N6XY@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein, family 7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DctP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002026_01136 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1541038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADEGWEIAVVPK MGYG000000212_00409 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG1879@1|root,COG1879@2|Bacteria,1TRBC@1239|Firmicutes,24DQX@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_00409 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 767641 0 0 0 0 1101123 0 908955 0 0 0 0 0 0 0 505717 305970 0 0 1286155 0 1143205 0 603713 0 554223 0 0 1729288 0 0 0 0 510801 0 0 583045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468602 0 0 0 0 0 0 0 0 0 1467882 0 0 0 0 1106355 0 1342389 0 0 0 1056147 0 0 0 1068713 971126 0 0 1774651 0 1554952 0 828389 0 1401842 1638408 0 1180650 0 0 0 0 1644914 0 0 1447852 0 1020762 0 0 0 0 496373 0 597264 0 0 0 420822 0 0 0 460845 815066 0 0 1336284 0 336730 0 785776 0 423729 779302 0 1767767 0 0 0 0 617952 0 0 364815 0 320823 0 0 0 0 138360 0 0 0 0 0 214001 0 0 0 0 324853 0 0 0 0 0 0 0 0 289473 374649 0 0 0 0 0 0 276162 0 0 495117 0 +AADEKPDAPMISSVK MGYG000001338_03066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG2340@1|root,COG2340@2|Bacteria 1.0 2|Bacteria 1.0 S 1.0 peptidase inhibitor activity 1.0 - 1.0 - 1.0 3.4.24.40 1.0 ko:K01406 1.0 ko01503,map01503 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Big_2,CAP,CBM_4_9,CBM_X2,Cadherin,DUF1080,DUF4114,DUF4214,DUF4430,FTP,Flg_new,G5,Glyco_hydro_127,Glyco_hydro_16,Glyco_hydro_3,Glyco_hydro_3_C,LysM,PPC,Peptidase_M10_C,Peptidase_M4,Peptidase_M4_C,SH3_3,SLH,fn3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03066 1.0 serralysin. Serratia marcescens extracellular proteinase. An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.-!-There is broad specificity in cleavage of the insulin B chain, with some species variations.-!-The pH optimum for digesting various proteins is about 9-10.-!-Belongs to peptidase family M10A.-!-Formerly EC 3.4.24.4. Preferential cleavage of bonds with hydrophobic residues in P1'. 1.0 1.0 1.0 1.0 Cationic antimicrobial peptide (CAMP) resistance 1.0 K01406:prtC; serralysin [EC:3.4.24.40] 1.0 none 1.0 0 0 0 0 200628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248462 0 0 0 0 0 0 0 598751 314407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192039 0 0 0 0 79875 0 0 0 0 198236 0 0 0 98789 0 0 0 0 0 0 0 0 0 0 206353 0 0 0 0 0 0 0 0 0 0 0 0 228034 0 0 0 0 232488 0 0 0 0 176624 0 0 219485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1920021 0 0 0 0 0 0 0 0 0 0 0 0 1794890 0 0 0 0 1572928 0 0 0 0 1437353 0 0 2137253 1516444 0 0 0 0 0 0 +AADEKSAVK MGYG000001425_00725 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Tissierellales|f__Peptoniphilaceae|g__Peptoniphilus_A|s__Peptoniphilus_A senegalensis|m__MGYG000001425 1.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,22G0C@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family 1.0 lysS 1.0 - 1.0 6.1.1.6 1.0 ko:K04567 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03658 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DUF2156,tRNA-synt_2,tRNA-synt_2_TM,tRNA_anti-codon,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001425_00725 1.0 lysine--tRNA ligase. lysyl-tRNA synthetase. - ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K04567:KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9552044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADELGVTFT(Ethanolamine) MGYG000000133_00205 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00205 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3791559 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADELGVTY(Tyr->Phe)K MGYG000001338_00111;MGYG000000184_02413 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_00111 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 313710 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 242822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 650818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245417 0 0 641337 0 0 0 0 0 0 0 0 0 0 131680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351878 0 0 0 0 500219 0 0 0 0 0 0 0 0 0 0 0 0 0 2937541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7445685 0 0 0 0 0 +AADELGVTYK MGYG000001338_00111;MGYG000000184_02413 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_00111 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 3811508 5029408 4269913 2225909 4530492 4209259 1011235 4906524 0 4442304 6922828 4761381 4160235 3478235 5190356 6324270 0 6576264 4111698 5242324 3453310 5025167 3238237 1919312 5805657 2767715 2937925 5014401 3594927 3697307 1832318 3701815 2728665 3502364 3361207 2059270 2487762 3890142 0 11635603 1790701 3689940 2507843 0 0 5133836 2682124 1905752 0 1587187 0 2328646 2311363 2144616 3709714 6905630 2452602 4066628 2356084 1759864 4243528 0 2462822 2844296 3319438 7286606 3100275 2141082 8802901 0 2091281 4147822 3692229 0 2961799 2106214 2883040 7972833 2359843 3238579 1325059 2800078 1836174 3365366 1928645 3488887 3275345 3471393 2905945 2957719 3276684 4638748 3749660 1463106 2782310 2842317 2843169 4475583 2294147 2172917 3312199 2611670 3723495 2841045 2714533 4135779 3135173 3740827 0 2753220 2398301 1545373 2571783 3477527 2816763 10419306 1905419 3000471 5493421 1094407 3039839 2229881 2523263 3294534 3006162 3769553 2807535 2529021 2260367 4682596 6284163 2675127 1974229 3614023 2338918 3750351 945941 3948830 1992319 1589784 2813451 4211024 3789837 3091666 10195826 3748824 4386958 1016192 1749370 2147823 1815594 4627046 2676288 5259329 4786660 3002287 2086485 2036299 3864497 3785866 2284951 2393133 5435645 4788209 1693141 4505210 3375154 3922322 2983825 1669859 1988819 591415 3164013 4065454 3988377 3080865 2505907 2064965 3108651 5059820 3558321 681774 4147426 4625379 6962283 2961396 2389969 2813759 663297 4869947 +AADELKEYK MGYG000004869_04033 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lactonifactor|s__Lactonifactor sp009677585|m__MGYG000004869 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000004869_04033 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2552394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADENDALYVPTDNTVAANTGIVDGIC(Carbamidomethyl)RPAK MGYG000001300_00090 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3WHHG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01989 1.0 - 1.0 M00247 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 - 1.0 - 1.0 - 1.0 ABC_sub_bind,BPD_transp_2,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00090 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01989:K01989; putative tryptophan/tyrosine transport system substrate-binding protein 1.0 none 1.0 391499 0 808666 0 0 0 483711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400834 408306 0 0 0 0 0 0 734991 0 0 0 530463 463796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225837 338298 0 0 0 0 0 0 399061 0 0 0 292018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1275480 0 1144652 0 0 0 2536510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1443215 1113720 0 0 0 0 0 0 969766 0 0 0 1331342 997928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADESKELFEGR MGYG000002494_01908 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0685@1|root,KOG0564@2759|Eukaryota 1.0 2759|Eukaryota 1.0 E 1.0 methylenetetrahydrofolate reductase (NAD(P)H) activity 1.0 MTHFR1 1.0 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.0 1.5.1.20,3.6.4.12 1.0 ko:K00297,ko:K10901 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko03440,ko03460,map00670,map00720,map01100,map01120,map01200,map01523,map03440,map03460 1.0 M00295,M00377,M00414 1.0 R01224,R07168 1.0 RC00081 1.0 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 1.0 - 1.0 - 1.0 - 1.0 BT1,DEAD,DUF1712,EamA,Helicase_C,Homoserine_dh,Hormone_recep,MTHFR,RecQ_Zn_bind,peroxidase,zf-C4 1.0 - 1.0 - 1.0 - 1.0 AA0 1.0 MGYG000002494_01908 1.0 methylenetetrahydrofolate reductase [NAD(P)H]. | DNA helicase. MTHFR. A flavoprotein (FAD).-!-The enzyme catalyzes the reversible conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, playing an important role in folate metabolism by regulating the distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis.-!-This enzyme, characterized from Protozoan parasites of the genus Leishmania, is unique among similar characterized eukaryotic enzymes in that it lacks the C-terminal allosteric regulatory domain (allowing it to catalyze a reversible reaction) and uses NADH and NADPH with equal efficiency under physiological conditions. cf. EC 1.5.1.53, EC 1.5.1.54, and EC 1.5.7.1.-!-Formerly EC 1.1.1.68, EC 1.1.1.171, EC 1.1.99.15 and EC 1.7.99.5. | DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA.-!-Some of them unwind duplex DNA with a 3' to 5' polarity, other show 5' to 3' polarity or unwind DNA in both directions.-!-Some helicases unwind DNA as well as RNA.-!-May be identical with EC 3.6.4.13. (1) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH. (2) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH. | ATP + H2O = ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Antifolate resistance|Homologous recombination|Fanconi anemia pathway 1.0 K00297:metF, MTHFR; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]|K10901:BLM, RECQL3, SGS1; bloom syndrome protein [EC:5.6.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1013324 0 0 1456336 877134 0 0 0 0 0 0 0 0 0 994905 0 0 0 0 1715203 0 1187248 0 0 0 0 1350444 671754 0 0 782137 0 0 0 0 736648 0 0 128725 0 0 101576 316782 0 0 0 0 0 0 0 0 0 77870 0 0 0 0 258909 0 0 0 0 0 0 140077 0 0 0 0 0 0 0 0 153839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 807794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADEVA(Ala->Gly)ALIDK MGYG000000171_00799;MGYG000000200_01407;MGYG000000184_00793;MGYG000000212_01426 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 0.5 186801|Clostridia 1.0 M 0.5 Cobalt chelatase (CbiK) 0.5 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_00799 0.25 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1749538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4729488 0 0 0 0 7819581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADEVAALIDK MGYG000000171_00799;MGYG000000200_01407;MGYG000000184_00793;MGYG000000212_01426 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 0.5 186801|Clostridia 1.0 M 0.5 Cobalt chelatase (CbiK) 0.5 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_00799 0.25 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 0 787708 795311 0 0 1318298 0 0 0 0 1076543 1697088 0 0 0 0 0 0 0 0 0 1560671 0 1355086 0 0 0 0 3983525 948171 0 0 668678 0 0 0 0 796930 0 276104 0 0 0 0 0 0 0 0 121866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3078177 0 0 0 0 0 0 0 0 0 0 0 389042 0 0 0 0 0 0 0 193138 744771 0 0 0 0 0 0 0 0 0 108403 0 214326 0 0 0 0 1369629 329246 0 0 656248 0 0 0 0 461544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12969929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385429 0 0 0 0 0 144152 0 0 0 0 0 0 0 0 0 317794 0 291581 0 0 0 0 0 0 0 0 0 0 0 0 0 343546 +AADEVGALIDK MGYG000001338_01847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,NAD_binding_7,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01847 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 1522172 5112060 1647834 954818 2823140 1295779 664490 1509521 0 1478779 3018332 1420004 1565123 1066641 1674633 1626183 1526269 2920457 1017607 1815743 0 1441751 2414988 567025 1900823 997947 983017 2911644 0 1126796 1443906 4582399 1300283 1252847 0 990173 948726 1527982 0 9345792 907830 0 1332268 1019062 0 0 0 927820 1358469 964840 1124246 997424 806383 740441 394857 10459618 1011488 0 0 872072 0 1492537 1249082 1095012 0 0 0 1145503 8575643 0 1001805 1476847 0 1392938 0 701688 1421661 10769992 1439378 1281347 826147 1047578 1042491 1425137 0 1343722 1491597 2886962 1311626 1180687 1766660 1686453 1130200 1110188 1308024 1329083 0 1551824 1696488 925824 1505159 1522223 1396128 0 1183682 3197702 2374748 8820223 2804102 1686482 0 942707 1343471 2063912 701022 11611271 1362497 890828 2478123 640010 1106599 754080 0 817894 1490455 1277190 1265610 750418 497051 1067693 949025 1865895 393973 715547 0 1019646 659856 1204454 652302 565827 678760 1941781 1103335 868469 7409221 5420999 1556064 655422 0 887863 943738 2398626 901514 14871264 4571871 1012289 1124653 672691 1512594 1532405 0 556308 1082454 1636571 989786 1505188 1249591 2358962 856238 2513435 740944 1078458 0 1309564 6251284 1441396 1078590 682720 868250 7471938 1299168 864876 6211592 6675522 6844177 1420338 0 684876 430649 3483475 +AADFANKVHAGEITNAAGEK MGYG000000262_02071 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,25VI8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 2.2.1.2,5.3.1.9 1.0 ko:K01810,ko:K13810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00004,M00007,M00114 1.0 R01827,R02739,R02740,R03321 1.0 RC00376,RC00439,RC00563,RC00604 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02071 1.0 transaldolase. | glucose-6-phosphate isomerase. glycerone transferase. | phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]|K13810:tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9] 1.0 none 1.0 0 0 0 0 0 292302 0 0 0 0 0 0 0 0 0 0 0 0 0 669983 0 359403 0 287389 0 0 0 0 0 0 0 0 0 203531 0 0 0 0 0 0 0 123797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 798047 0 581236 0 0 0 0 0 0 0 0 0 440248 0 0 802287 609547 0 795042 0 344392 0 0 0 0 0 0 0 0 0 959404 804479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADFASM(Oxidation)VVK MGYG000000802_01545;MGYG000000188_00827;MGYG000000333_00450;MGYG000004746_01526;MGYG000003274_01601;MGYG000002947_01134;MGYG000002978_00225;MGYG000002065_00755;MGYG000002970_00371;MGYG000001567_00996;MGYG000002775_01124 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0696@1|root,COG0696@2|Bacteria,2HHGK@201174|Actinobacteria,4CUJ8@84998|Coriobacteriia 0.9090909090909091 84998|Coriobacteriia 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 0.9090909090909091 gpmI 0.9090909090909091 - 1.0 5.4.2.12 0.9090909090909091 ko:K15633 0.9090909090909091 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 0.9090909090909091 M00001,M00002,M00003 1.0 R01518 0.9090909090909091 RC00536 0.9090909090909091 ko00000,ko00001,ko00002,ko01000 0.9090909090909091 - 1.0 - 1.0 - 1.0 Metalloenzyme,Phosphodiest,Sulfatase,iPGM_N 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000802_01545 0.09090909090909091 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Glycolysis / Gluconeogenesis|Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.9090909090909091 K15633:gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] 0.9090909090909091 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADFASMVVK MGYG000000802_01545;MGYG000000188_00827;MGYG000000333_00450;MGYG000004746_01526;MGYG000003274_01601;MGYG000002947_01134;MGYG000002978_00225;MGYG000002065_00755;MGYG000002970_00371;MGYG000001567_00996;MGYG000002775_01124 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0696@1|root,COG0696@2|Bacteria,2HHGK@201174|Actinobacteria,4CUJ8@84998|Coriobacteriia 0.9090909090909091 84998|Coriobacteriia 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 0.9090909090909091 gpmI 0.9090909090909091 - 1.0 5.4.2.12 0.9090909090909091 ko:K15633 0.9090909090909091 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 0.9090909090909091 M00001,M00002,M00003 1.0 R01518 0.9090909090909091 RC00536 0.9090909090909091 ko00000,ko00001,ko00002,ko01000 0.9090909090909091 - 1.0 - 1.0 - 1.0 Metalloenzyme,Phosphodiest,Sulfatase,iPGM_N 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000802_01545 0.09090909090909091 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Glycolysis / Gluconeogenesis|Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.9090909090909091 K15633:gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] 0.9090909090909091 none 1.0 0 2852228 0 439809 1020930 0 502393 0 645971 0 1398504 0 2503488 516287 0 2185835 693596 1519135 0 782380 0 0 1401375 0 0 0 289764 1499658 728598 346576 265534 0 0 0 0 0 0 0 0 441934 0 798600 716823 0 733432 0 458161 0 1331510 0 1008848 248094 0 575816 0 2146507 0 626616 0 0 1073492 0 0 0 476221 1917132 929214 1293431 1026687 0 0 0 0 0 0 0 0 839417 0 804848 0 0 450406 0 498108 0 375743 0 1475835 802094 0 1947278 1720262 338079 0 1161803 0 0 609992 0 0 0 1101890 1051827 1228984 1010272 0 0 0 0 0 0 0 0 0 1182144 0 1354539 2437931 0 898680 0 901189 0 3089946 0 4312945 1067673 0 0 1398484 790125 0 1458511 0 0 0 0 0 0 960577 1274707 2350451 1941604 1454421 0 0 0 0 0 0 0 0 348985 0 460507 0 0 625427 0 136738 0 602344 0 786703 363967 0 781938 174889 568825 0 0 0 0 520051 0 0 0 122598 806272 396753 170361 384901 0 0 0 0 0 0 0 +AADFDKQGR MGYG000002478_01470 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01470 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03072:secD; preprotein translocase subunit SecD|K12257:secDF; SecD/SecF fusion protein 1.0 none 1.0 0 0 1196767 0 1529162 747991 0 516312 0 0 1316147 0 1881435 813469 0 1423218 0 712590 0 0 872805 828535 1012764 1340667 0 0 976332 1070480 0 0 1247030 0 1128584 0 0 0 0 947878 0 0 682203 0 1186175 564068 0 551701 0 0 722481 0 2027317 855661 0 1212306 0 365380 0 0 638395 637607 854048 398210 0 0 770575 734929 0 0 491390 0 495863 0 0 0 0 411063 0 0 483322 0 660132 429958 0 272119 0 0 397845 0 978046 404572 0 774179 0 304216 0 0 372572 363604 410757 421302 0 0 343053 490893 0 0 560149 0 297470 0 0 0 0 376977 0 0 588515 0 249853 810353 0 197529 0 0 587303 0 247255 161951 0 382606 0 457569 0 0 0 1032449 307804 888309 0 0 99226 6605 0 0 303848 0 612097 0 0 0 0 838664 0 0 549729 0 1216977 716738 0 510826 0 0 769111 0 2589715 420850 0 1245682 0 749824 0 0 332914 577510 797273 629552 0 0 560858 331794 0 0 891889 0 428860 0 0 0 0 839206 +AADFEK MGYG000002065_00816;MGYG000003266_01415;MGYG000001642_00536;MGYG000004681_00135 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CURX@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 alcohol dehydrogenase 1.0 adh1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002065_00816 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 2528803 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1334038 0 490324 0 0 577588 0 0 0 0 60646 0 0 0 0 0 0 0 0 0 0 0 150545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338474 0 160296 0 0 70063 0 0 0 0 4750630 0 0 0 0 0 0 0 0 0 0 0 474727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10813 0 201233 0 0 219280 0 0 0 0 449394 0 0 0 0 0 0 0 0 0 0 0 1631110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1167331 0 765203 0 0 161256 0 0 0 0 1306790 0 0 0 0 0 0 0 0 0 0 0 170294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 509801 0 345545 0 0 720071 0 0 0 0 422801 0 0 0 0 0 0 0 0 0 0 +AADFEKILK MGYG000002970_01542;MGYG000002947_01395;MGYG000003266_01415;MGYG000000188_01843;MGYG000001642_00536;MGYG000004681_00135 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CURX@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 alcohol dehydrogenase 1.0 adh1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002970_01542 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADFIMENVKER MGYG000000280_00174 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__AM51-8|s__AM51-8 sp003478275|m__MGYG000000280 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,27I7R@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000280_00174 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1889768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADFLAIGK MGYG000001302.1_01195 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0149@1|root,COG0149@2|Bacteria,4NE2F@976|Bacteroidetes,2FNEK@200643|Bacteroidia,22UAZ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_01195 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 544372 0 0 0 0 414272 0 0 0 0 442272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88681 0 0 0 0 216862 0 0 0 0 278856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2225057 0 0 0 0 3371266 0 0 0 0 1913907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179751 0 0 0 0 94258 0 0 0 0 454150 0 0 0 0 0 0 0 0 0 0 +AADFLDGIK MGYG000000224_00483;MGYG000000442_01373;MGYG000000054_03942;MGYG000000196_03983;MGYG000002549_02931;MGYG000002455_03893;MGYG000004763_01698;MGYG000002291_02263;MGYG000001378_05033;MGYG000001345_04693;MGYG000001346_01525 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000000224_00483 0.09090909090909091 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 1133246 785984 542527 1161275 703311 766599 1370099 1011998 1211934 1039546 2225667 1239850 582305 1026204 1224772 1057306 915557 319236 909755 899580 866380 832687 368261 1121270 955615 1237706 671051 0 761129 1257994 927169 255872 674226 1326107 800946 1207038 813918 618770 1304648 611915 1267610 1490019 851597 1164892 870411 1362729 1370960 1739162 2466392 1721911 847440 1550843 1585498 1101784 1104600 104163 1070873 1119073 1238045 1107127 299895 905450 1257676 1438560 1253682 187702 925321 1089921 815186 1072684 1199152 1101036 1232998 1315440 1443836 1058483 1088361 779110 1241389 876939 1165298 911407 1179716 916474 1018453 681578 2170284 1264441 859776 1002659 650781 945347 825129 1184692 682965 893406 902676 711746 975894 983521 871539 1010161 861186 747581 1011177 1089049 1048498 740603 838457 605099 811115 1156378 1026163 1140218 1408003 1123504 1269002 1235636 1369888 1293364 1271402 1407500 1430446 1513345 1763925 1695261 1518506 1463532 1623515 1554133 1422933 1183439 1187053 1320999 1403377 1069109 1255238 1155718 1302420 1449260 1245101 1006723 1207540 1386164 1395563 1378450 1351172 1377627 1649184 1550313 1461031 1116213 739087 440107 505109 672214 1181366 1221971 836865 1047343 1102655 720463 1829447 867242 1024753 463408 724406 985737 800276 1397539 591481 1183122 526627 1174053 955154 1144340 1029024 679618 647456 738621 626678 1212503 651744 672189 286914 1076497 963331 460376 181811 628824 +AADFNALPTWK MGYG000000223_03085 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0205@1|root,COG0205@2|Bacteria,1UN7X@1239|Firmicutes,3VNZJ@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 G 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 MGYG000000223_03085 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1272207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1888746 3906876 0 0 0 0 0 0 0 0 0 301376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 905040 2247551 0 0 0 0 0 0 0 0 0 749346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADFSAIVNFK MGYG000004717_01610 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Megamonas|s__Megamonas hypermegale|m__MGYG000004717 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4H27A@909932|Negativicutes 1.0 909932|Negativicutes 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004717_01610 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 266190 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633722 0 0 0 0 1217768 0 0 0 0 589694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADGAIAATQAEK MGYG000001315_00850 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,27IZT@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Pyridine nucleotide-disulphide oxidoreductase 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_00850 1.0 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 K00384:trxB, TRR; thioredoxin reductase (NADPH) [EC:1.8.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 106206 0 0 0 0 263148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220990 0 0 529421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604590 0 0 0 0 863679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADGEYR MGYG000000133_00908;MGYG000002517_02577;MGYG000000139_02038 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,3Y05I@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 D 1.0 Could be involved in septation 1.0 spoVG 1.0 - 1.0 - 1.0 ko:K06412 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 SpoVG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00908 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06412:spoVG; stage V sporulation protein G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 257807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 717168 0 0 0 0 0 0 0 0 57664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72706 0 0 0 0 0 0 0 0 333676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 494039 0 0 0 0 0 0 0 0 788799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADGEYRDIAHPINSNTR MGYG000004271_00115 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 Could be involved in septation 1.0 spoVG 1.0 - 1.0 - 1.0 ko:K06412 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 SpoVG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00115 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06412:spoVG; stage V sporulation protein G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADGKTDLYYR MGYG000000243_01558 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1506@1|root,COG1506@2|Bacteria,4NF7I@976|Bacteroidetes,2FMJD@200643|Bacteroidia,4ANDK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase, S9A B C family, catalytic domain protein 1.0 pepX2 1.0 - 1.0 3.4.14.5 1.0 ko:K01278 1.0 ko04974,map04974 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko01002,ko04090,ko04147 1.0 - 1.0 - 1.0 - 1.0 DPPIV_N,Peptidase_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01558 1.0 dipeptidyl-peptidase IV. Xaa-Pro-dipeptidylaminopeptidase. A membrane-bound serine-type peptidase in mammals.-!-EC 3.4.14.11 catalyzes a similar reaction.-!-Belongs to peptidase family S9B. Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline. 1.0 1.0 1.0 1.0 Protein digestion and absorption 1.0 K01278:DPP4, CD26; dipeptidyl-peptidase 4 [EC:3.4.14.5] 1.0 none 1.0 0 0 531380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 634150 0 0 0 0 675097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253306 0 0 282136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147133 0 0 0 0 224213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 189605 0 0 0 0 0 0 0 80933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265937 +AADGNNFGTVLIPEGLIEFIPAIKK MGYG000003697_01061 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 MGYG000003697_01061 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7321280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADGPMPQTR MGYG000003185_01053;MGYG000003185_01074;MGYG000003142_01865;MGYG000004804_00945;MGYG000003142_01879;MGYG000000143_00646;MGYG000002994_01317;MGYG000000445_01370;MGYG000000258_00266;MGYG000004769_00412;MGYG000003236_02455;MGYG000004769_00437;MGYG000004717_00227;MGYG000001646_01118;MGYG000001749_02490;MGYG000001412_04734;MGYG000001470_03722;MGYG000004804_01395;MGYG000001712_00119;MGYG000001485_02164;MGYG000001464_00103;MGYG000001508_00032;MGYG000001431_01181 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4H22P@909932|Negativicutes 0.2608695652173913 91061|Bacilli 0.2608695652173913 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.6521739130434783 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.7391304347826086 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003185_01053 0.043478260869565216 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 507910 0 0 259807 0 0 0 0 319971 0 0 0 0 361146 184187 860142 0 0 0 373686 288590 145063 0 0 0 545393 200858 0 236933 0 273425 0 0 0 0 307203 0 0 1061459 0 0 1018135 0 0 0 0 997096 0 0 0 0 794634 675208 355968 0 0 0 936318 0 933392 0 0 0 389409 587832 0 760697 0 914942 0 0 0 0 965071 0 0 337787 0 0 438991 0 0 0 0 341315 0 0 0 0 649763 319125 0 0 0 0 290287 0 140826 0 0 0 259213 438450 0 0 0 424124 0 0 0 0 461739 0 0 2076410 0 0 2416262 0 0 0 0 1837483 0 0 0 0 2138221 2121777 4097543 0 0 0 3360707 1427662 4682262 0 0 0 9208287 3053908 0 2706121 0 2858183 0 0 0 0 2910238 0 0 284669 0 0 857279 0 0 0 0 1008931 0 0 0 0 555395 414475 725718 0 0 0 957744 635110 926402 0 0 0 500198 1050424 0 873522 0 581328 0 0 0 0 1102131 +AADGTAQYYTK MGYG000002470_04263;MGYG000004899_00606 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FN3Y@200643|Bacteroidia,4AP89@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002470_04263 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 389920 0 0 0 0 0 0 0 0 0 581791 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADGTVTGVK MGYG000003694_02659 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter faecis|m__MGYG000003694 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000003694_02659 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 269035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480642 0 0 0 0 449134 0 0 0 0 183589 0 0 0 0 0 0 0 0 0 286483 0 0 1117676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1395413 0 0 0 0 619741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220835 0 0 0 0 833434 0 0 0 0 407863 0 0 0 0 0 0 0 0 0 0 0 0 10098177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21973411 0 0 0 0 9228879 0 0 0 0 17611767 0 0 0 0 0 0 0 0 0 18268293 0 0 457393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447421 0 0 0 0 286794 0 0 0 0 330308 0 0 0 0 391752 0 0 0 0 945012 +AADGVILITTK MGYG000000174_03825 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides faecis|m__MGYG000000174 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000174_03825 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1729921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1998101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADGVILVTTK MGYG000001489_00895 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides goldsteinii|m__MGYG000001489 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001489_00895 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 592497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5470540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADGVIYITTK MGYG000004763_02544 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG4206@1|root,COG4206@2|Bacteria,4PMK4@976|Bacteroidetes,2G0EG@200643|Bacteroidia,4AMPZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004763_02544 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1552021 0 0 0 0 1848543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADGVIYITTKR MGYG000004763_02544 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG4206@1|root,COG4206@2|Bacteria,4PMK4@976|Bacteroidetes,2G0EG@200643|Bacteroidia,4AMPZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004763_02544 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1884661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADGVQPQSETVWR MGYG000002293_00507 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0480@1|root,COG0480@2|Bacteria,4NE9X@976|Bacteroidetes,2FM1M@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000002293_00507 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 309293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332079 0 0 0 0 0 0 0 3173356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2293382 0 0 0 0 3700073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADGVVIITTK MGYG000003363_02494 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900766195|m__MGYG000003363 1.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKGC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003363_02494 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1827242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1980547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADGYTYYMAEALLDKVLGR MGYG000002517_00846 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) 1.0 ileS 1.0 - 1.0 6.1.1.5 1.0 ko:K01870 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03656 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00846 1.0 isoleucine--tRNA ligase. isoleucyl-tRNA synthetase. - ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01870:IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5] 1.0 none 1.0 355979 0 0 0 272121 0 0 0 310640 0 0 0 0 248580 0 0 0 0 0 0 0 0 0 0 0 371845 0 0 0 0 0 0 0 0 0 0 0 0 144517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219496 0 0 0 0 0 0 0 0 0 0 15062972 0 5274094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6398376 0 0 0 0 0 0 0 0 0 0 6324442 0 52447160 0 0 0 29761596 0 0 0 19309779 0 0 0 0 90933781 0 0 0 0 0 0 0 0 0 0 0 49283808 0 0 0 0 0 0 0 0 0 0 72995057 0 +AADHAHAAQKPEAVEI MGYG000003921_00100 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3WIWI@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly 1.0 rplM 1.0 - 1.0 - 1.0 ko:K02871 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_00100 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02871:RP-L13, MRPL13, rplM; large subunit ribosomal protein L13 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390722 0 0 0 0 441953 0 0 0 0 246370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690527 0 0 0 0 465797 0 0 0 0 597931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 554732 0 0 0 0 438915 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209113 0 0 0 0 487591 0 0 0 0 149680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 142251 0 0 0 0 596116 0 0 0 0 2255491 0 0 0 0 0 0 0 0 0 0 +AADIAAIGITNQR MGYG000002934_02584;MGYG000000164_01754;MGYG000002274_01022;MGYG000001496_03285;MGYG000002993_00205;MGYG000003819_01517;MGYG000000404_00178;MGYG000000370_01160;MGYG000002517_00523;MGYG000002105_01106;MGYG000002212_02389 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 0.36363636363636365 186801|Clostridia 0.9090909090909091 F 0.5454545454545454 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002934_02584 0.09090909090909091 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 1175684 0 785287 0 1474421 0 1133954 1698226 1397368 1884138 0 0 1364960 1331877 2481302 1001621 834979 0 1679718 1525442 0 0 0 0 1893058 1399771 0 0 0 0 0 0 509618 1290736 1281356 0 1038632 627724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 142648 0 0 240605 0 0 0 0 0 187489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADIADIR MGYG000002970_01267;MGYG000002065_00912;MGYG000004746_00558;MGYG000003266_00145;MGYG000000188_00405;MGYG000003122_01006;MGYG000004681_00319;MGYG000002947_01668;MGYG000000802_00031;MGYG000000333_01777;MGYG000001718_01732;MGYG000004875_01408 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CV00@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9 1.0 ko:K08483 1.0 ko02060,map02060 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002970_01267 0.08333333333333333 phosphoenolpyruvate--protein phosphotransferase. sugar--PEP phosphotransferase enzyme I. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 K08483:ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] 1.0 none 1.0 0 2807089 453817 0 0 0 0 0 0 0 764196 0 1285095 228177 0 1486288 154394 0 0 708832 0 0 0 0 0 0 0 0 0 208475 0 0 223427 0 0 0 0 477001 0 656486 211977 0 0 0 0 0 0 0 870576 0 751837 213300 0 634879 210812 0 0 512954 0 0 0 0 0 0 0 0 0 488179 0 0 210760 0 0 0 0 470915 0 0 0 0 0 0 0 0 0 0 224709 0 1059741 0 0 1398347 1030179 0 0 1040297 0 0 0 0 0 0 0 0 0 736789 0 0 1053415 0 0 0 0 0 0 1148988 900497 0 0 0 0 0 0 0 2785309 0 2985280 1019367 0 4475312 1891721 0 0 1287500 0 0 0 0 0 0 0 0 0 1858283 0 0 1021966 0 0 0 0 1085699 0 186201 571957 0 0 0 0 0 0 0 550282 0 577334 472228 0 822705 360419 0 0 274118 0 0 0 0 0 0 0 0 0 247538 0 0 439520 0 0 0 0 323475 +AADIAGIGITNQR MGYG000000077_01442;MGYG000000262_02304 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,25VA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 F 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_01442 0.5 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1023511 0 0 1087615 0 0 0 0 0 0 0 0 0 2522430 1894680 0 0 1864358 0 1455264 0 1263158 0 0 967063 0 2269924 0 0 0 1578186 0 0 0 0 1642335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADIEGFLAEESKAEAGK MGYG000002528_02847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02847 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053043 0 0 0 0 514370 0 0 0 0 808413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADIGAIGITNQR MGYG000000489_01562;MGYG000002517_00259;MGYG000000389_02030 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000489_01562 0.3333333333333333 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 78022 0 0 0 635186 0 0 726293 0 732755 0 0 0 684494 949237 0 0 0 913529 599747 0 0 0 70490 901342 670112 376952 0 89227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92517 116724 0 0 0 0 0 0 0 0 0 107664 0 0 0 0 57950 0 0 0 0 0 156498 0 0 74198 0 0 0 0 0 0 0 403233 0 5970692 0 0 6414354 3712055 2779985 4605336 6667728 9678135 3751584 0 2402751 0 7031006 6845773 0 6812413 0 9127343 9245314 2898930 1237498 0 1549616 3530144 4436494 6554872 0 3297228 3698060 2206825 0 0 2377678 5163410 4337423 6376983 0 0 0 0 0 0 93666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 96094 0 0 0 0 0 0 0 +AADIIR MGYG000000074_02400;MGYG000000098_00813;MGYG000000196_04138 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,4AN6T@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 COG2086 Electron transfer flavoprotein beta subunit 0.6666666666666666 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02400 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 403264 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 349946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADIKDVTYR MGYG000000223_00596 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,3VNU4@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9 1.0 ko:K08483 1.0 ko02060,map02060 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_00596 1.0 phosphoenolpyruvate--protein phosphotransferase. sugar--PEP phosphotransferase enzyme I. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 K08483:ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178745 0 0 0 0 0 0 0 0 686315 0 0 0 0 0 0 0 0 0 218036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 737845 0 0 0 0 0 0 0 0 1481048 0 0 0 0 0 0 0 0 0 576330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92631 0 0 0 0 0 0 0 0 +AADILAQEGISVR MGYG000004828_01159;MGYG000002485_00028 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG3958@1|root,COG3958@2|Bacteria,378ZW@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004828_01159 0.5 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 883370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADILEK MGYG000004271_01895;MGYG000002517_00838;MGYG000000271_01394;MGYG000001615_03000;MGYG000003335_02805;MGYG000004431_00578;MGYG000001065_02180;MGYG000001338_00069;MGYG000000389_01232;MGYG000004719_01604;MGYG000002247_02694 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia 0.6363636363636364 186801|Clostridia 1.0 F 0.6363636363636364 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) 0.6363636363636364 purE 0.6363636363636364 - 1.0 5.4.99.18 0.6363636363636364 ko:K01588 0.6363636363636364 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 0.6363636363636364 M00048 0.6363636363636364 R07405 0.6363636363636364 RC01947 0.6363636363636364 ko00000,ko00001,ko00002,ko01000 0.6363636363636364 - 1.0 - 1.0 - 1.0 AIRC 0.6363636363636364 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01895 0.09090909090909091 5-(carboxyamino)imidazole ribonucleotide mutase. N(5)-carboxyaminoimidazole ribonucleotide mutase. In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates.-!-In the absence of EC 6.3.2.6, the reaction is reversible.-!-The substrate is readily converted into 5-amino-1-(5-phospho-D- ribosyl)imidazole by non-enzymic decarboxylation. 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1- (5-phospho-D-ribosyl)imidazole-4-carboxylate. 0.6363636363636364 0.6363636363636364 0.6363636363636364 0.6363636363636364 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 0.6363636363636364 K01588:purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] 0.6363636363636364 none 1.0 1052598 1199702 723830 5349792 4029791 812757 0 0 0 1157059 1755274 3489029 1245699 1027766 0 0 884279 0 1157733 1130215 1584168 1273593 0 974324 1168062 677139 0 0 0 0 773411 915075 802269 440683 0 0 1130951 765208 0 1391545 215763 0 749097 451310 0 0 0 0 432089 0 538345 282079 0 0 0 0 0 410949 318604 0 0 0 0 239321 0 0 0 0 1671528 721728 567053 0 0 0 394344 246181 436775 1684644 669411 474294 0 413877 0 0 0 609014 233514 423459 583214 284920 0 0 473712 0 479087 0 0 620542 0 0 417831 519080 0 0 0 0 403434 1274028 717847 765558 0 0 0 303899 2155653 2170547 1032396 2122280 1995714 1153801 0 0 0 1405632 1091446 688763 1205818 2286761 0 0 1184248 0 653285 2116874 957577 629228 0 624730 0 1679680 0 0 0 0 2170603 2690160 1077470 1170437 0 0 819162 1230671 0 3413739 2961115 973064 1818772 0 0 0 0 3055546 2263886 2022411 2398451 3614099 0 0 2496541 0 2362114 2089263 2198337 2854316 0 2522986 2893736 2523812 0 0 0 0 2598067 2527883 3766700 2662621 0 0 2670037 0 +AADILR MGYG000000074_02400;MGYG000002549_02817;MGYG000001496_01438;MGYG000000133_02450;MGYG000000196_04138;MGYG000001337_03724;MGYG000001345_00398;MGYG000001315_02145 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,4AN6T@815|Bacteroidaceae 0.5 976|Bacteroidetes 0.625 C 1.0 COG2086 Electron transfer flavoprotein beta subunit 0.5 etfB 0.625 - 1.0 - 0.625 ko:K03521 0.625 - 0.625 - 0.625 - 0.625 - 0.625 ko00000 0.625 - 1.0 - 1.0 - 1.0 ETF 0.625 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02400 0.125 - - - - 0.625 0.625 0.625 0.625 - 0.625 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.625 none 1.0 1160859 0 0 1214029 0 0 0 1002951 0 1396401 1612161 0 0 2011343 0 0 0 1098444 0 0 0 0 888884 0 1247193 1390000 0 0 0 0 0 0 0 0 0 0 1551333 0 1692057 0 0 1279700 0 0 0 1566196 0 1509417 1578161 0 0 1340129 0 0 0 0 0 0 0 0 563081 0 1422606 1519075 0 2206049 0 0 0 0 0 0 0 0 1497229 0 1045197 0 0 1251470 0 0 0 1253772 0 1173292 1526128 0 0 1344549 0 0 0 0 0 0 0 0 1194226 0 1257262 1408416 0 859115 0 0 0 0 0 0 0 0 1193027 0 1470679 0 0 1701098 0 0 0 0 0 2997120 1481902 0 0 1683966 0 0 0 0 0 0 0 0 672487 0 1026148 1145734 0 1261508 0 0 0 0 0 0 0 0 1965915 0 2659743 0 0 3018195 0 0 0 2274079 0 0 1755100 0 0 1455068 0 0 0 621724 0 0 0 0 792005 0 2719961 3661296 0 854106 0 0 0 0 0 0 0 0 3488781 0 +AADIM(Oxidation)K MGYG000001770_02443;MGYG000003697_02383;MGYG000004797_03938;MGYG000001789_01650;MGYG000000325_00235;MGYG000002478_03963;MGYG000002293_02246;MGYG000003486_01435;MGYG000000781_01961;MGYG000001306_02131;MGYG000000243_01707 domain d__Bacteria 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 0.5454545454545454 976|Bacteroidetes 0.8181818181818182 EF 0.5454545454545454 COG0462 Phosphoribosylpyrophosphate synthetase 0.5454545454545454 prs 0.8181818181818182 - 1.0 2.7.6.1 0.8181818181818182 ko:K00948 0.8181818181818182 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 0.8181818181818182 M00005 0.8181818181818182 R01049 0.8181818181818182 RC00002,RC00078 0.8181818181818182 ko00000,ko00001,ko00002,ko01000 0.8181818181818182 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 0.8181818181818182 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001770_02443 0.09090909090909091 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 0.8181818181818182 0.8181818181818182 0.8181818181818182 0.8181818181818182 Pentose phosphate pathway|Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.8181818181818182 K00948:PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 0.8181818181818182 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADIMK MGYG000001770_02443;MGYG000003697_02383;MGYG000004797_03938;MGYG000001789_01650;MGYG000000325_00235;MGYG000002478_03963;MGYG000002293_02246;MGYG000003486_01435;MGYG000000781_01961;MGYG000001306_02131;MGYG000000243_01707 domain d__Bacteria 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 0.5454545454545454 976|Bacteroidetes 0.8181818181818182 EF 0.5454545454545454 COG0462 Phosphoribosylpyrophosphate synthetase 0.5454545454545454 prs 0.8181818181818182 - 1.0 2.7.6.1 0.8181818181818182 ko:K00948 0.8181818181818182 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 0.8181818181818182 M00005 0.8181818181818182 R01049 0.8181818181818182 RC00002,RC00078 0.8181818181818182 ko00000,ko00001,ko00002,ko01000 0.8181818181818182 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 0.8181818181818182 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001770_02443 0.09090909090909091 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 0.8181818181818182 0.8181818181818182 0.8181818181818182 0.8181818181818182 Pentose phosphate pathway|Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.8181818181818182 K00948:PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 0.8181818181818182 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 1258122 0 0 1025106 1447603 1108225 0 0 0 1604717 0 0 0 0 1936183 0 0 2599782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520783 0 0 1056517 1002250 1078035 0 0 0 2454965 0 0 0 0 878832 0 0 1118277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 747560 0 0 998133 0 1740510 0 0 0 883947 0 0 0 0 1350394 0 0 370571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184270 0 0 1126733 2608826 952502 0 0 0 911635 0 0 0 0 2327058 0 0 1496354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1400334 0 0 704015 1588680 601928 0 0 0 1235624 0 0 0 0 1219572 0 0 665934 0 0 0 0 0 0 0 +AADIMKEAGAISVR MGYG000004797_03938;MGYG000002478_03963;MGYG000000243_01707 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EF 1.0 COG0462 Phosphoribosylpyrophosphate synthetase 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_03938 0.3333333333333333 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00948:PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADIQAYEIGLTDSK MGYG000002549_02730 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG1196@1|root,COG1196@2|Bacteria,4P0K9@976|Bacteroidetes,2FRA0@200643|Bacteroidia,4APBZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 D 1.0 domain, Protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_02730 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 722102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 482544 0 0 0 0 0 0 0 0 0 0 0 0 0 439691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318005 0 0 0 585706 0 0 0 0 0 0 0 0 0 628355 0 0 0 201323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 539622 0 0 0 0 0 0 0 0 0 308443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475135 0 0 0 419367 0 0 0 0 0 0 0 0 0 2817623 0 0 0 5824380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2260257 0 0 0 2940817 0 0 0 +AADISNAIR MGYG000003166_02092;MGYG000000195_02922;MGYG000002619_00241;MGYG000000022_00970 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WH0G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 NADH oxidase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Oxidored_FMN,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_02092 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1638656 0 0 0 0 2764761 0 0 0 0 2873694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1317970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADIVLQAAIAAGAPK MGYG000002323_02346;MGYG000000093_03243;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206;MGYG000002534_02768;MGYG000003883_03730 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.8571428571428571 1236|Gammaproteobacteria 1.0 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.8571428571428571 adhE 1.0 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_02346 0.14285714285714285 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 786180 836035 1437175 764368 541165 3384587 1560598 1211494 987934 1297778 410887 886948 278075 870496 620041 279249 720298 0 762814 738507 838926 3801177 0 3836238 913609 656919 770472 0 1454703 1051912 910012 661074 1141067 1040819 1095762 655736 812870 1209052 14574500 18237010 16650843 16498192 24485860 29752006 21226548 12985771 16317291 0 6251523 14799347 10112658 19630833 18926503 14485198 28562668 0 22761992 18020488 22786335 43165826 0 28289069 21595215 0 14145626 0 27620421 17964922 9470720 11737287 18622860 14874758 11922539 12635696 11580882 17451290 997866 1121862 1447396 965338 1003727 4856953 1233329 1283765 657110 1243409 836022 840228 1071516 963971 808170 1119930 962507 0 984475 971760 996931 3934001 0 4487220 1006441 816464 1139894 0 792465 914043 1005576 824517 2576234 1692580 1181064 1049658 695323 1714242 1662086 530753 1233237 1093474 604906 1976158 1787559 1509527 934784 825253 346688 698691 907360 995955 897148 740256 576045 0 1050753 939122 2040431 1797811 0 755813 1630100 1512165 1557393 0 539901 1039367 175798 728721 971255 2820489 2498169 1695267 980150 561074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADIVLQAAIAAGAPK(Cation_Na) MGYG000002323_02346;MGYG000000093_03243;MGYG000002506_00529;MGYG000002515_01649;MGYG000002494_03206;MGYG000002534_02768;MGYG000003883_03730 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.8571428571428571 1236|Gammaproteobacteria 1.0 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.8571428571428571 adhE 1.0 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_02346 0.14285714285714285 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 204046 0 0 297570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319864 0 264226 0 0 0 0 0 0 0 0 110654 0 0 0 0 221198 0 0 908323 0 0 1114280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1555182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238944 0 0 0 0 335071 0 0 77887 0 0 314067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163460 0 79545 0 0 0 0 0 0 0 0 62983 0 0 0 0 101030 0 0 0 0 0 316982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203230 +AADK(Lys->Gln)PFLMPVEDVMTISGR MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002059_00460 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1182821 0 0 0 0 0 948013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADKDATVLAAVSAIDK MGYG000002274_02947;MGYG000004679_00122;MGYG000000022_01840 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3WKKU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_02947 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02968:RP-S20, rpsT; small subunit ribosomal protein S20 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADKEGAPMK MGYG000002517_03263 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit 1.0 rpsR 1.0 - 1.0 - 1.0 ko:K02963 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S18 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_03263 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02963:RP-S18, MRPS18, rpsR; small subunit ribosomal protein S18 1.0 none 1.0 62134 0 0 0 0 0 0 100415 0 0 0 0 0 0 0 0 0 0 0 196439 0 0 0 0 0 0 66247 0 0 0 0 0 0 0 0 0 0 109058 24241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100203 0 0 0 42823 103443 0 0 0 0 0 0 0 0 0 88691 0 0 0 46919 0 0 0 0 0 40751 0 0 0 0 94776 81712 89049 0 0 0 0 0 0 0 0 81454 0 0 495934 0 46162 0 0 0 0 389430 744270 148681 0 0 0 242619 0 0 0 0 0 426363 0 0 0 0 541326 592607 636251 0 0 0 0 0 1579246 0 0 98058 470793 88034 168716 0 581079 0 0 0 0 266549 373760 666782 0 0 0 710948 0 0 0 0 0 129070 0 0 0 0 397760 360058 843497 0 0 0 0 0 663868 0 0 554623 463520 495773 +AADKEGAPMKR MGYG000002517_03263 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit 1.0 rpsR 1.0 - 1.0 - 1.0 ko:K02963 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S18 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_03263 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02963:RP-S18, MRPS18, rpsR; small subunit ribosomal protein S18 1.0 none 1.0 141560 81804 0 165412 36734 78691 0 80561 150578 130682 51839 71579 0 52732 269444 193931 185960 0 0 337306 0 131764 0 0 203982 198303 169706 0 0 77118 0 0 0 0 85634 159881 196029 51098 45379 0 0 0 0 0 0 0 0 0 96432 0 0 53362 0 0 0 0 0 0 0 0 0 0 51928 56991 0 0 0 0 0 0 0 0 0 23899 0 0 50603 69418 46576 57117 0 0 0 47467 65048 0 0 31370 0 0 114303 49034 0 0 0 67150 0 73622 0 0 0 0 87300 0 0 29157 0 0 138753 0 138315 38598 138907 0 1448809 410281 251051 1900977 724554 314005 0 1453171 2593187 464082 623350 607908 0 1501109 544144 740185 1381617 0 0 1467290 0 314703 0 0 1392005 1937698 1803390 0 0 956504 0 532264 124949 0 1920764 471062 2926840 225607 1351591 1364328 1928043 106732 373955 850103 0 1034558 1464609 4812096 1526136 1759671 0 2506619 1838363 1069043 1156753 0 0 769638 0 1062635 0 1169448 2017326 1385846 2005260 0 0 525515 0 268930 2556904 0 2307691 2065405 1848759 1391402 +AADKFPQAQLVLSAK MGYG000000271_00867;MGYG000004271_01998 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Desulfoferrod_N,Desulfoferrodox,Flavodoxin_1,Flavodoxin_5,Lactamase_B,Lactamase_B_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00867 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADKPFLM(Oxidation)PVEDVM(Oxidation)TISGR MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002059_00460 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 590645 0 0 0 0 317657 0 0 0 0 321100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 108801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312105 0 0 0 0 509311 0 0 0 0 289642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384857 0 0 0 0 476864 0 0 0 0 142781 0 0 0 0 0 0 0 0 0 0 +AADKPFLM(Oxidation)PVEDVMTISGR MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002059_00460 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 444411 0 0 1079560 387216 0 0 0 0 745346 456147 0 0 1830942 0 1647801 1456915 0 490419 0 475543 460845 201150 0 0 0 786035 0 423877 0 1426844 0 0 0 0 0 0 0 193298 0 0 299930 261918 0 0 0 0 257593 690767 0 0 373356 0 391392 507935 0 322272 0 177129 608318 256752 0 0 0 376598 0 362531 0 256053 0 0 0 0 0 0 0 165993 0 0 649141 0 0 0 0 0 614220 395405 0 0 110867 0 0 496519 0 422357 0 0 478601 0 0 0 0 155331 0 290301 0 143360 0 0 0 0 0 0 0 94353 0 0 161940 146555 0 0 0 0 103735 388282 0 0 77413 0 53193 325049 0 110691 0 87467 333606 470340 0 0 0 336877 0 225054 0 153828 0 0 0 0 0 0 0 0 0 0 74702 175942 0 0 0 0 0 3533196 0 0 0 0 2832444 1738338 0 112576 0 99274 1252815 0 0 0 0 212391 0 70219 0 0 0 0 0 0 0 0 +AADKPFLMPV(Val->Xle)EDVMTISGR MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002059_00460 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1277330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADKPFLMPVEDVM(Oxidation)TISGR MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002059_00460 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 610533 529730 0 0 559430 509736 0 836993 0 610584 0 913804 681125 0 881418 857187 1091712 1654030 0 706529 0 812727 729700 207933 619791 415473 0 930605 0 0 0 0 0 0 519236 0 355269 0 145967 337637 0 0 341165 0 0 696112 0 0 0 836735 309929 0 0 298385 0 444848 0 0 0 0 475446 290436 520939 276264 0 386426 0 0 0 0 0 0 520224 0 0 0 238228 312098 0 0 361517 138200 0 259694 0 0 0 492382 189859 0 593798 480908 734417 148007 0 705524 0 211674 310543 217630 445327 254998 0 231048 0 0 0 0 0 0 194666 0 289546 0 247080 282141 0 0 373764 0 0 417482 0 253517 0 724930 216266 0 277055 335424 227221 430991 0 174809 0 287854 551523 319690 395625 116287 0 590092 0 0 0 0 0 0 378842 0 90181 0 256831 419225 0 0 554146 334276 0 225998 0 281960 0 977477 172116 0 515011 411553 254739 901808 0 443994 0 361052 849636 341930 282181 173764 0 1067906 0 0 0 0 0 0 159448 0 136159 0 +AADKPFLMPVEDVMTISGR MGYG000002059_00460;MGYG000003921_01124;MGYG000004732_02398;MGYG000000084_02000;MGYG000003937_01027 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002059_00460 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 17024164 0 396771 0 15413968 4319821 0 34151797 13448446 0 0 30840136 0 0 141412 0 0 11245888 0 0 0 13222267 1695463 14440753 0 183965 0 2587934 0 0 0 0 14524912 0 15407314 0 300792 113355 44258 0 3399067 0 198745 157492 0 8399862 320665 0 0 2141768 0 0 297764 0 0 21143704 0 0 0 284276 22096635 484136 0 311731 0 15432613 0 0 0 0 1695998 0 190812 0 4922386 194212 615868 0 4020668 0 4061390 218382 0 5230400 5482537 0 0 183158 0 0 4689346 0 0 6599348 0 0 0 1361728 958184 270873 0 176569 0 7980301 0 0 0 0 308926 0 3910680 0 760619 425592 184304 0 6013929 0 4747512 8612803 0 920296 5729981 0 0 25164607 0 0 9029495 0 0 318300 0 0 0 273991 1607319 3850050 0 880844 0 21492563 0 0 0 0 9467975 0 347186 0 81421 2309258 1929557 0 0 0 17867280 202920 0 0 5789558 0 0 12788628 0 0 0 0 0 30956500 0 0 0 266355 42279158 171733 0 0 0 44198908 0 0 0 0 17052789 0 1270230 0 172719 0 +AADLAAK MGYG000000074_01219 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1579@1|root,COG1579@2|Bacteria,4NE36@976|Bacteroidetes,2FPGP@200643|Bacteroidia,22U60@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Zinc ribbon domain 1.0 - 1.0 - 1.0 - 1.0 ko:K07164 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 zf-RING_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01219 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07164:K07164; uncharacterized protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1523670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLAGR MGYG000001302.1_01989 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG1866@1|root,COG1866@2|Bacteria,4NEGI@976|Bacteroidetes,2FNYK@200643|Bacteroidia,22U24@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA 1.0 pckA 1.0 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 1.0 4.1.1.49 1.0 ko:K01610 1.0 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 1.0 M00003,M00170 1.0 R00341 1.0 RC00002,RC02741 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEPCK_ATP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_01989 1.0 phosphoenolpyruvate carboxykinase (ATP). phosphopyruvate carboxylase. - ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01610:pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 605037 0 0 350438 0 0 0 0 736242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 621029 0 0 0 0 345186 0 0 0 0 227040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLDAIHDTVHEM(Oxidation)AKDEAR MGYG000000171_01528 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_01528 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 266841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 776631 0 0 0 98283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLDAIHDTVHEMAKDEAR MGYG000000171_01528 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_01528 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 908154 0 0 0 0 970225 0 261089 0 219345 1009298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380954 0 0 0 0 106988 0 0 0 168076 236966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102905 0 0 0 0 281731 0 363991 0 365671 374821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151840 0 0 0 0 0 0 0 0 0 502215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLDTANVLR MGYG000001300_00560;MGYG000002223_01031 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3WGKI@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 citrate synthase 1.0 gltA2 1.0 - 1.0 2.3.3.1 1.0 ko:K01647 1.0 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 1.0 M00009,M00010,M00012,M00740 1.0 R00351 1.0 RC00004,RC00067 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Citrate_synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00560 0.5 citrate (Si)-synthase. citrate oxaloacetate-lyase [(pro-3S)-CH2COO->acetyl-CoA]. The stereospecificity of this enzyme is opposite to that of EC 2.3.3.3, which is found in some anaerobes.-!-Citrate synthase for which the stereospecificity with respect to C2 of oxaloacetate has not been established are included in EC 2.3.3.16.-!-Formerly EC 4.1.3.7. acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+). 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Glyoxylate and dicarboxylate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K01647:CS, gltA; citrate synthase [EC:2.3.3.1] 1.0 none 1.0 0 672681 0 479838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 693829 0 0 0 0 0 609709 0 0 0 0 0 0 0 0 0 0 0 0 0 1515002 1260948 0 1804187 0 0 0 0 0 0 0 983438 0 0 0 0 0 0 1381615 1503396 0 0 0 0 1507297 1347402 0 0 0 0 0 0 0 0 0 0 1545715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690549 1227308 0 958165 0 0 0 0 0 0 0 1249095 0 0 0 0 0 0 899402 754148 0 0 0 0 1312209 916048 0 0 0 0 0 0 0 0 0 0 842739 0 0 208662 0 924872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLFSK MGYG000000196_04140 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG1960@1|root,COG1960@2|Bacteria,4NEHA@976|Bacteroidetes,2FM28@200643|Bacteroidia,4AN5I@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 acd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,AcylCoA_dehyd_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04140 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 2196346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2245098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613022 0 0 0 0 0 0 +AADLGLSDVTVK MGYG000002993_01622 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-170|s__CAG-170 sp000432135|m__MGYG000002993 1.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,2N6G4@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate-binding protein PnrA-like 1.0 tmpC 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002993_01622 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07335:bmpA, bmpB, tmpC; basic membrane protein A and related proteins 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 605593 0 0 0 0 388928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585327 0 0 0 0 678759 0 0 0 0 1590378 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLHDVGQR MGYG000003683_01304 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CZ52@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsI 1.0 - 1.0 2.7.3.9 1.0 ko:K08483 1.0 ko02060,map02060 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 EIIA-man,PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N,PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 CE9 1.0 MGYG000003683_01304 1.0 phosphoenolpyruvate--protein phosphotransferase. sugar--PEP phosphotransferase enzyme I. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 K08483:ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1028768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1802929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1061184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLIR MGYG000004756_00803;MGYG000000074_02400;MGYG000000196_04138;MGYG000001562_02164;MGYG000001345_00398 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia 0.6 976|Bacteroidetes 1.0 C 1.0 Electron transfer flavoprotein 0.6 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004756_00803 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1868918 0 0 1519033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLLPVDWDKTSTGK MGYG000001313_02440 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG1435@1|root,COG1435@2|Bacteria,4P1V6@976|Bacteroidetes,2FX4S@200643|Bacteroidia,4AV49@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_02440 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 980394 0 0 0 0 805876 0 0 0 0 887509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLLPVDWDNTTTGKPTFGNNQQR MGYG000002455_04253 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG0614@1|root,COG0614@2|Bacteria,4NGP1@976|Bacteroidetes,2FNKG@200643|Bacteroidia,4AMD2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_04253 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1322394 0 0 0 0 1076029 0 0 0 0 1255265 0 0 0 0 0 0 0 0 0 0 +AADLLR MGYG000003372_02346;MGYG000001777_01710;MGYG000002506_01324;MGYG000000074_02400;MGYG000002494_03510;MGYG000000196_04138;MGYG000002515_01853;MGYG000001337_03724;MGYG000001345_00398;MGYG000002477_02675 domain d__Bacteria 1.0 COG1536@1|root,COG1536@2|Bacteria,1MV9X@1224|Proteobacteria,1RM9B@1236|Gammaproteobacteria,3XMFG@561|Escherichia 0.5 1236|Gammaproteobacteria 0.5 N 0.5 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation 0.5 fliG 0.5 GO:0001539,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0006996,GO:0008150,GO:0009288,GO:0009425,GO:0009987,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0040011,GO:0042802,GO:0042995,GO:0043226,GO:0043228,GO:0044085,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0044780,GO:0044781,GO:0048870,GO:0051179,GO:0051674,GO:0070925,GO:0071840,GO:0071944,GO:0071973,GO:0097588 0.5 - 0.9 ko:K02410 0.5 ko02030,ko02040,map02030,map02040 0.5 - 0.9 - 0.9 - 0.9 ko00000,ko00001,ko02035 0.5 - 1.0 - 1.0 - 1.0 FliG_C,FliG_M,FliG_N 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003372_02346 0.1 - - - - 0.9 0.9 0.9 0.9 Bacterial chemotaxis|Flagellar assembly 0.5 K02410:fliG; flagellar motor switch protein FliG 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 863849 0 0 0 0 0 771596 0 0 0 0 0 0 0 0 0 0 0 0 1424544 0 0 1161464 0 0 0 0 0 0 0 0 0 0 0 208152 0 0 0 0 0 0 0 0 0 0 1106184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1645232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLMADILGGK MGYG000000175_02877 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Muricomes|s__Muricomes sp000509105|m__MGYG000000175 1.0 COG1609@1|root,COG1609@2|Bacteria,1UP7H@1239|Firmicutes,25H7W@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 LacI,Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000175_02877 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2613008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2999552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2468343 0 0 0 0 0 0 0 0 0 +AADLMK MGYG000001770_02443;MGYG000003697_02383;MGYG000004797_03938;MGYG000002478_03963;MGYG000002293_02246;MGYG000003486_01435;MGYG000001306_02131;MGYG000000243_01707;MGYG000001787_01419 domain d__Bacteria 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 0.5555555555555556 976|Bacteroidetes 0.8888888888888888 EF 0.5555555555555556 COG0462 Phosphoribosylpyrophosphate synthetase 0.5555555555555556 prs 0.8888888888888888 - 1.0 2.7.6.1 0.8888888888888888 ko:K00948 0.8888888888888888 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 0.8888888888888888 M00005 0.8888888888888888 R01049 0.8888888888888888 RC00002,RC00078 0.8888888888888888 ko00000,ko00001,ko00002,ko01000 0.8888888888888888 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001770_02443 0.1111111111111111 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 Pentose phosphate pathway|Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.8888888888888888 K00948:PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 0.8888888888888888 none 1.0 0 0 0 0 0 649457 0 0 0 0 0 0 0 0 0 0 0 1853994 0 0 0 1483759 1532439 0 0 0 0 1914146 0 0 0 0 2094212 0 0 0 0 0 0 0 807298 0 0 583691 0 0 0 0 0 0 0 0 0 228847 0 305624 0 0 0 0 0 1263182 0 0 0 2063155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 694512 0 0 0 0 0 0 0 0 0 2440497 0 0 0 0 0 1115574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLTAH MGYG000002293_01420;MGYG000003697_02155 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01420 0.5 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K00008:SORD, gutB; L-iditol 2-dehydrogenase [EC:1.1.1.14] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2781972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1574975 0 0 0 0 3476657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLTAHQVL MGYG000002293_01420;MGYG000003697_02155 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01420 0.5 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K00008:SORD, gutB; L-iditol 2-dehydrogenase [EC:1.1.1.14] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6227108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4123412 0 0 0 0 6045133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLTAHQVLVN MGYG000002293_01420;MGYG000003697_02155 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01420 0.5 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K00008:SORD, gutB; L-iditol 2-dehydrogenase [EC:1.1.1.14] 1.0 none 1.0 0 0 509508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319758 0 0 0 0 812060 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379868 0 0 0 0 0 0 0 2079175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1622957 0 0 0 0 1778726 0 0 675463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLTAHQVLVNIK MGYG000002293_01420;MGYG000003697_02155 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1063@1|root,COG1063@2|Bacteria,4NE11@976|Bacteroidetes,2FNP5@200643|Bacteroidia,4AMM9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 1.1.1.14 1.0 ko:K00008 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00014 1.0 R00875,R01896 1.0 RC00085,RC00102 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01420 0.5 L-iditol 2-dehydrogenase. sorbitol dehydrogenase. This enzyme is widely distributed and has been described in archaea, bacteria, yeast, plants and animals.-!-It acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.-!-Enzymes from different organisms or tissues display different substrate specificity.-!-The enzyme is specific to NAD(+) and can not use NADP(+). L-iditol + NAD(+) = H(+) + keto-L-sorbose + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K00008:SORD, gutB; L-iditol 2-dehydrogenase [EC:1.1.1.14] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1108170 7044551 0 2376983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3595439 2183254 4302412 0 0 0 0 5449212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLTTVEAGK MGYG000001300_02558 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3WIYH@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 ET 1.0 Belongs to the bacterial solute-binding protein 3 family 1.0 artP 1.0 - 1.0 - 1.0 ko:K02029,ko:K02030 1.0 - 1.0 M00236 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1.3 1.0 - 1.0 - 1.0 SBP_bac_3,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02558 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02029:ABC.PA.P; polar amino acid transport system permease protein|K02030:ABC.PA.S; polar amino acid transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101714 0 0 0 0 0 0 0 +AADLVISAESAK MGYG000000177_01234 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 COG2998@1|root,COG2998@2|Bacteria,1UI9K@1239|Firmicutes,25EEI@186801|Clostridia,36S90@31979|Clostridiaceae 1.0 2|Bacteria 1.0 H 1.0 Copper amine oxidase N-terminal domain 1.0 - 1.0 - 1.0 - 1.0 ko:K05772 1.0 ko02010,map02010 1.0 M00186 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.6.2,3.A.1.6.4 1.0 - 1.0 - 1.0 CAP,Cu_amine_oxidN1,NHL,PBP_like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000177_01234 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K05772:tupA, vupA; tungstate transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4304068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9796500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLVQQR MGYG000003266_00462 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900762015|m__MGYG000003266 1.0 COG1418@1|root,COG1418@2|Bacteria,2I9DW@201174|Actinobacteria,4CURU@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 NU 1.0 Endoribonuclease that initiates mRNA decay 1.0 rny 1.0 - 1.0 - 1.0 ko:K18682 1.0 ko03018,map03018 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03019 1.0 - 1.0 - 1.0 - 1.0 DUF3552,HD,KH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003266_00462 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation 1.0 K18682:rny; ribonucrease Y [EC:3.1.-.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADLVSQMTVDDK MGYG000001619_00077 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA9502|s__UBA9502 sp900540335|m__MGYG000001619 1.0 COG1472@1|root,COG3266@1|root,COG5263@1|root,COG1472@2|Bacteria,COG3266@2|Bacteria,COG5263@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,21ZUH@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Glycosyl hydrolase family 3 C-terminal domain 1.0 - 1.0 - 1.0 3.2.1.21 1.0 ko:K05349 1.0 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 1.0 - 1.0 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 1.0 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH3 1.0 - 1.0 Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C 1.0 - 1.0 GH3 1.0 GH3 1.0 GH3 1.0 MGYG000001619_00077 1.0 beta-glucosidase. gentobiase. Wide specificity for beta-D-glucosides.-!-Some examples also hydrolyze one or more of the following: beta-D- galactosides, alpha-L-arabinosides, beta-D-xylosides and beta-D- fucosides. Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose. 1.0 1.0 1.0 1.0 Cyanoamino acid metabolism|Starch and sucrose metabolism|Phenylpropanoid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K05349:bglX; beta-glucosidase [EC:3.2.1.21] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADM(Oxidation)TGADIEAMTR MGYG000002515_03654;MGYG000002323_03993;MGYG000002500_00408;MGYG000002507_00343;MGYG000002502_01843;MGYG000002366_04479;MGYG000000235_04430 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,3ZIPY@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_03654 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02867:RP-L11, MRPL11, rplK; large subunit ribosomal protein L11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381387 416940 518714 0 727727 606371 0 904107 0 0 0 0 0 0 0 0 0 0 0 0 779033 0 761781 0 0 0 0 596634 0 0 0 0 0 0 0 0 501668 0 440726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400164 0 400574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 554798 0 0 878524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618549 0 0 0 0 0 0 213871 0 0 0 0 0 0 0 0 632240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADMTGADIEAM(Oxidation)TR MGYG000002515_03654;MGYG000002323_03993;MGYG000002500_00408;MGYG000002507_00343;MGYG000002502_01843;MGYG000002366_04479;MGYG000000235_04430 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,3ZIPY@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_03654 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02867:RP-L11, MRPL11, rplK; large subunit ribosomal protein L11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436973 0 552008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300248 0 363698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADMTGADIEAMTR MGYG000002515_03654;MGYG000002323_03993;MGYG000002500_00408;MGYG000002507_00343;MGYG000002502_01843;MGYG000002366_04479;MGYG000000235_04430 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0080@1|root,COG0080@2|Bacteria,1RA2M@1224|Proteobacteria,1S22R@1236|Gammaproteobacteria,3ZIPY@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_03654 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02867:RP-L11, MRPL11, rplK; large subunit ribosomal protein L11 1.0 none 1.0 1689115 1348862 1660780 1661535 1041343 2892723 3201843 2774055 1692816 2549691 847192 2005120 0 1726024 1406529 471242 2133940 0 1600848 1884759 2191816 2458614 0 4133846 1805150 1823073 2164896 0 2429615 2502606 1881752 1864501 1725210 2197579 1780422 2141445 1459263 1952458 5395766 5318683 5234087 6306209 6092118 12613396 7300910 4752233 4709318 9479303 2679525 4673654 4094438 7876329 5712408 4546235 7666780 0 7208652 4739219 7259876 12843135 0 8793634 7262288 6052492 4716327 0 9920299 7842708 3412694 5119935 6680694 5164164 6118575 5180915 5423258 5848155 1652665 1341046 2048591 1234816 2187554 4135349 2184691 2096090 2046367 2337924 1663321 1945102 1796749 1978948 1665287 1897920 2147269 0 1645467 1637096 2121335 3594215 0 4399857 2231494 1547293 1588790 0 1523077 1816683 2029265 1649015 1695069 2298643 2445611 1968753 1318971 2205171 3582646 3115152 3143344 3262602 3030782 6070555 4487240 3777653 2567175 6023201 2980074 2879410 4780312 3085234 2856826 2817858 3233869 0 3366825 2172112 4621339 5051099 0 3880550 3824954 2923673 4272588 0 3367276 3189689 1791876 2854852 3581770 4643138 4701309 3898847 2546743 3037548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADN(Deamidated)VAALIDK MGYG000000142_01624;MGYG000000133_00237 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 1.0 186801|Clostridia 1.0 M 1.0 Cobalt chelatase (CbiK) 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01624 0.5 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2056286 0 0 0 0 0 0 0 0 0 1199147 0 0 1484040 0 0 1257369 1858878 1161664 0 0 0 0 0 0 0 0 0 0 1258993 0 0 0 0 0 0 1168266 0 0 0 0 2666628 0 0 0 0 1277856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2634002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 503928 1423276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADNNLTAPMYLR MGYG000000003_00524 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,2G3E7@200643|Bacteroidia,22UFS@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_00524 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 590444 0 0 0 0 0 0 0 0 0 0 0 0 0 880094 0 0 0 0 0 0 0 0 0 0 1012764 0 0 0 0 0 0 0 0 0 0 0 0 576496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397526 0 0 0 0 0 0 0 0 0 0 0 0 0 930692 0 0 0 0 0 0 0 0 0 0 736806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADPEIAGYSSNADVQR MGYG000002478_00836 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AWE5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00836 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 445796 0 0 444986 0 0 0 0 0 0 0 0 0 0 920272 0 0 0 0 1021599 0 0 0 0 832298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADPELAITEFK MGYG000001306_01209 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_01209 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 462336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1503484 0 0 0 0 2138128 0 0 0 0 1514861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADPELAITEFKR MGYG000001306_01209 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_01209 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 135255 0 68166 0 0 0 0 0 0 0 0 0 0 0 0 68662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119620 0 0 58344 722072 0 1008289 935986 1084115 0 0 993064 838245 0 0 0 0 0 0 1322092 1001149 3250666 0 0 0 0 3646293 0 0 865345 940713 2860686 0 0 981233 0 912882 919375 1006228 764413 701217 1027768 54317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172795 0 0 0 0 0 0 0 0 0 0 74979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADPELAVADFK MGYG000003693_02548 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_02548 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1729464 0 0 0 0 1192722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADPELAVADFKR MGYG000003693_02548 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_02548 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587163 0 0 0 2669544 0 0 0 0 3749323 0 0 0 0 2507941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70320 0 0 0 0 190323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498153 0 0 0 0 439454 0 0 0 0 341434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADPY(Didehydro)VVVDSK MGYG000002057_00680 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Dysosmobacter|s__Dysosmobacter sp001916835|m__MGYG000002057 1.0 2DX6Y@1|root,343NU@2|Bacteria,1VVG9@1239|Firmicutes,25GRP@186801|Clostridia,2N903@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002057_00680 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADPYVVVDSK MGYG000002057_00680 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Dysosmobacter|s__Dysosmobacter sp001916835|m__MGYG000002057 1.0 2DX6Y@1|root,343NU@2|Bacteria,1VVG9@1239|Firmicutes,25GRP@186801|Clostridia,2N903@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002057_00680 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 13327530 10286266 0 0 0 11879019 19104982 0 0 0 0 9863494 0 0 0 0 0 0 0 0 0 8824592 0 14863500 11810977 13749406 13280559 0 13719790 13252180 13026022 0 0 14995018 0 0 14186612 0 185921 0 0 0 0 0 156963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1606625 872361 0 0 0 1038405 2391002 0 0 0 0 702824 0 0 0 0 0 0 0 0 0 390486 0 1179653 1982021 1355312 1532397 0 1368585 797464 939674 0 0 1736970 0 0 1562414 0 7609379 5921404 0 0 0 7915152 7801366 0 0 0 0 7812397 0 0 0 0 0 0 0 0 0 5701730 0 5785288 8053836 9390127 7594872 0 9011407 8038184 6326712 0 0 10518233 0 0 9215739 0 1660877 1047788 0 0 0 1755687 1648028 0 0 0 0 1158068 0 0 0 0 0 0 0 0 0 1599437 0 1901505 1738320 1638558 1397245 0 2052765 1585571 1531427 0 0 1839913 0 0 1938007 0 +AADPYVVVDSKLQMK MGYG000002057_00680 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Dysosmobacter|s__Dysosmobacter sp001916835|m__MGYG000002057 1.0 2DX6Y@1|root,343NU@2|Bacteria,1VVG9@1239|Firmicutes,25GRP@186801|Clostridia,2N903@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002057_00680 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADQGN(Deamidated)GVAC(Carbamidomethyl)LYGNYSGDNMNVK MGYG000004735_02294 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,21YFJ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 2.7.1.121 1.0 ko:K05878 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_02294 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways 1.0 K05878:dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3058548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADQGNGVAC(Carbamidomethyl)LYGNYSGDNMNVK MGYG000004735_02294 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,21YFJ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 2.7.1.121 1.0 ko:K05878 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_02294 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways 1.0 K05878:dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2003746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADQIISTVK MGYG000000084_02402;MGYG000000573_00808;MGYG000001627_00605;MGYG000002059_00658 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,25VXK@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000084_02402 0.25 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 628406 0 0 0 0 0 373698 0 0 0 0 671346 0 0 0 0 0 0 0 0 0 0 455619 0 0 199009 0 0 0 0 0 0 374851 0 0 0 0 0 294955 0 0 0 0 0 411047 0 0 0 0 0 526219 0 0 0 264434 722134 0 0 0 0 554317 0 0 0 0 165517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 749266 0 0 0 0 0 0 0 0 0 0 0 137358 0 0 0 0 0 507698 0 0 0 0 0 0 0 0 0 0 1606865 0 0 1519857 0 0 0 0 0 4840531 0 0 0 0 1829421 3971280 0 0 0 1944992 2612880 1837263 0 0 0 6316887 0 2425314 2806658 0 1422283 0 0 0 0 1856330 0 0 0 0 0 0 0 0 0 0 0 562880 0 0 0 0 0 1301264 0 0 0 0 1115478 0 0 0 0 1223364 0 633723 0 0 0 0 0 0 0 0 +AADQLGLPYLK MGYG000001302.1_00591 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG3193@1|root,COG3193@2|Bacteria,4NKJX@976|Bacteroidetes,2FN1N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Starch-binding associating with outer membrane 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_00591 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8387581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADQSYLSGGSWGAGDVK MGYG000000243_02119 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02119 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444804 0 0 0 0 0 0 0 0 0 657354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADQSYLSGGSWGAGDVKYEDLNNDGK MGYG000000243_02119 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02119 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 484463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596296 0 0 426209 0 446245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163803 0 0 441273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 370770 0 319213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADQTDDNWK MGYG000001319_01847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,4BW46@830|Butyrivibrio 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001319_01847 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1736197 0 0 0 0 768943 0 0 0 0 1674540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADREAVEALLAK MGYG000002494_04092 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1MYN4@1224|Proteobacteria,1RMRN@1236|Gammaproteobacteria,3XP1B@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate 1.0 purL 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.0 6.3.5.3 1.0 ko:K01952 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04463 1.0 RC00010,RC01160 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECH74115_1262.ECH74115_3792,iECO111_1330.ECO111_3283,iECSP_1301.ECSP_3501,iECs_1301.ECs3423,iG2583_1286.G2583_3088,iJN746.PP_1037,ic_1306.c3080 1.0 AIRS,AIRS_C,GATase_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04092 1.0 phosphoribosylformylglycinamidine synthase. phosphoribosylformylglycinamidine synthetase. - ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D- ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D- ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01952:PFAS, purL; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138580 0 0 0 0 0 0 0 0 0 +AADREGAPM(Oxidation)KR MGYG000004271_01917 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit 1.0 rpsR 1.0 - 1.0 - 1.0 ko:K02963 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S18 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01917 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02963:RP-S18, MRPS18, rpsR; small subunit ribosomal protein S18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADREGAPMKR MGYG000004271_01917 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit 1.0 rpsR 1.0 - 1.0 - 1.0 ko:K02963 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S18 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01917 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02963:RP-S18, MRPS18, rpsR; small subunit ribosomal protein S18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADRTGRPATVK MGYG000000187_00978 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000187_00978 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADSFLKDNC(Carbamidomethyl)QDIVSAK MGYG000000133_02045 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3XZ9K@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location CytoplasmicMembrane, score 1.0 ntpI 1.0 - 1.0 - 1.0 ko:K02123 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 V_ATPase_I 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02045 1.0 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways 1.0 K02123:ATPVI, ntpI, atpI; V/A-type H+/Na+-transporting ATPase subunit I 1.0 none 1.0 713281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109801 0 0 0 0 0 0 0 0 0 0 0 0 123435 0 0 0 0 0 0 0 0 370470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379510 0 0 202862 0 0 0 0 0 0 0 151540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 818799 0 0 0 0 0 0 0 0 882116 0 0 1084034 0 0 0 0 0 0 0 0 0 0 0 0 596829 0 0 1013555 0 0 794560 0 0 0 0 527595 0 +AADSNVKVDAGK MGYG000001356_00079 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter sp000177015|m__MGYG000001356 1.0 COG1404@1|root,COG1404@2|Bacteria,1UM3J@1239|Firmicutes 1.0 1239|Firmicutes 1.0 O 1.0 S-layer homology domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001356_00079 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 57877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1205966 0 0 0 0 0 0 0 0 0 +AADSVVEELK MGYG000001881_01572 genome d__Bacteria|p__Verrucomicrobiota|c__Verrucomicrobiae|o__Verrucomicrobiales|f__Akkermansiaceae|g__Akkermansia|s__Akkermansia muciniphila_A|m__MGYG000001881 1.0 COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,2ITQ1@203494|Verrucomicrobiae 1.0 203494|Verrucomicrobiae 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 - 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000001881_01572 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADSVVEELKK MGYG000001881_01572 genome d__Bacteria|p__Verrucomicrobiota|c__Verrucomicrobiae|o__Verrucomicrobiales|f__Akkermansiaceae|g__Akkermansia|s__Akkermansia muciniphila_A|m__MGYG000001881 1.0 COG0459@1|root,COG0459@2|Bacteria,46S9U@74201|Verrucomicrobia,2ITQ1@203494|Verrucomicrobiae 1.0 203494|Verrucomicrobiae 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 - 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000001881_01572 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADVDEALQR MGYG000002494_00912 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0028@1|root,COG0028@2|Bacteria,1MWKP@1224|Proteobacteria,1RNYT@1236|Gammaproteobacteria,3ZJ68@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 EH 1.0 Thiamine pyrophosphate enzyme, central domain 1.0 poxB 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009987,GO:0016020,GO:0016043,GO:0016054,GO:0016491,GO:0016903,GO:0019752,GO:0019842,GO:0022607,GO:0030976,GO:0032787,GO:0036094,GO:0042802,GO:0042867,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052737,GO:0052738,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575,GO:1901681 1.0 1.2.3.3,1.2.5.1 1.0 ko:K00156,ko:K00158 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00207,R03145 1.0 RC00860,RC02745 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iSF_1195.SF0826,iSFxv_1172.SFxv_0895,iS_1188.S0867 1.0 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00912 1.0 pyruvate oxidase. | pyruvate dehydrogenase (quinone). pyruvic oxidase. | pyruvate oxidase. Two reducing equivalents are transferred from the resonant carbanion/enamine forms of 2-hydroxyethyl-thiamine-diphosphate to the adjacent flavin cofactor, yielding 2-acetyl-thiamine diphosphate (AcThDP) and reduced flavin.-!-FADH is reoxidized by O2 to yield H2O2 and FAD and AcThDP is cleaved phosphorolytically to acetyl phosphate and thiamine diphosphate. | This bacterial enzyme is located on the inner surface of the cytoplasmic membrane and coupled to the respiratory chain via ubiquinone.-!-Does not accept menaquinone.-!-Activity is greatly enhanced by lipids.-!-Requires thiamine diphosphate.-!-The enzyme can also form acetoin. H(+) + O2 + phosphate + pyruvate = acetyl phosphate + CO2 + H2O2. | a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K00156:poxB; pyruvate dehydrogenase (quinone) [EC:1.2.5.1]|K00158:spxB, poxL; pyruvate oxidase [EC:1.2.3.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3389528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5013346 0 4394560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADVDTLGDLVQFNK MGYG000002834_00467;MGYG000003697_01441 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002834_00467 0.5 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 1.0 none 1.0 0 0 596930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 761045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 851086 0 0 0 0 947512 0 0 0 0 690436 0 0 0 0 951181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1063281 0 0 0 0 1149215 0 0 0 0 0 0 0 1241567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1484574 0 0 0 0 756578 0 0 0 0 0 0 0 0 0 1367941 0 0 651599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683851 0 0 0 0 410908 0 0 0 0 537197 0 0 0 0 0 0 0 0 0 880382 +AADVDTVGDLVK MGYG000001420_02949;MGYG000004006_01195;MGYG000001562_01972;MGYG000004536_01537;MGYG000000414_01251;MGYG000002082_00459;MGYG000000003_00060;MGYG000003469_01152;MGYG000001546_01244;MGYG000000074_01934;MGYG000003952_00926;MGYG000004658_00182;MGYG000000053_00720;MGYG000001302.1_01192 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,22UPE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001420_02949 0.07142857142857142 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 1.0 none 1.0 1946497 1682108 943569 1995991 1148484 1981229 1923246 1309387 2201620 2033029 985475 2231543 1341566 2305552 2521408 1437621 2310384 0 2457126 2319629 2572287 1900105 0 2310761 1831441 2281392 2697321 0 1738406 3128587 1443302 2638675 1273290 806409 2002799 2447715 2022821 870071 1721710 927854 1725948 1950333 1403312 1158201 1004478 1842524 1855663 2316354 1085750 1875495 1064232 2079331 2236785 1309142 1306030 0 1957404 2054083 1581640 1320118 0 1034476 1743299 1784027 1707243 0 1523627 1707079 951646 1586597 1673780 1368398 1764037 1756910 1758948 1602039 2207576 1439634 2508110 1710748 2449391 1560444 1945731 2013868 2670176 1902441 1831107 2486349 1498429 2361148 1810880 1406766 1637283 0 1928281 2298224 2437918 1237365 0 1851900 2052677 1983010 1769489 0 2117725 2665540 1712712 1138651 1837271 2351643 2015424 2857449 2200934 2296172 1360185 1166765 2440049 2155682 1857859 2613156 2045040 2149739 2020011 2219760 1526753 2220880 987812 2147171 3108033 1729673 1951378 0 2373556 1456074 0 451765 0 487881 2240686 1811458 1574033 0 2444409 2462458 1697421 2326319 2370175 0 1538680 1841138 2547491 1954654 3838862 2798656 3417687 5780010 5518491 4869535 3796860 4012194 4330215 3861687 2008307 3675131 3958695 2526102 3670630 4437052 4393561 0 6295233 7235763 2938754 3815155 0 5252575 3814981 4844579 3180442 0 3906075 5906278 3132201 3068179 2141886 1240012 4322814 3368939 4844224 3719947 +AADVDTVGDLVK(Lys->Arg) MGYG000001420_02949;MGYG000004006_01195;MGYG000001562_01972;MGYG000004536_01537;MGYG000000414_01251;MGYG000002082_00459;MGYG000000003_00060;MGYG000003469_01152;MGYG000001546_01244;MGYG000000074_01934;MGYG000003952_00926;MGYG000004658_00182;MGYG000000053_00720;MGYG000001302.1_01192 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,22UPE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001420_02949 0.07142857142857142 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 1.0 none 1.0 0 0 775799 0 0 0 0 0 0 0 0 0 0 1171671 0 0 0 0 0 0 1358535 0 0 0 0 1405285 0 0 0 0 0 0 0 0 0 0 0 1148781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADVDTVGDLVR MGYG000001415_01644 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,22UPE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_01644 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 1.0 none 1.0 987736 1025602 928215 947493 0 0 1119102 1154224 1063542 1039466 1035960 0 0 0 0 0 0 0 0 1057315 0 1029914 0 1419874 0 0 1235018 0 0 1007651 1141682 1099876 1193637 1510762 1026558 1292548 1103995 0 0 174763 0 0 0 212672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311688 0 0 0 0 0 273385 0 240660 284496 364767 197466 0 525660 289954 271237 349904 129503 333363 0 0 0 0 0 0 0 0 0 0 0 0 394907 0 531214 262294 0 0 187357 293122 284932 0 579910 0 607376 369528 305011 624653 785063 586273 446731 0 673148 616488 506831 418575 466211 590998 0 0 0 0 0 0 0 0 645527 0 0 0 0 0 471213 393520 0 0 0 571288 501192 547518 403814 441356 514515 445629 0 360905 609892 178668 341006 0 0 0 0 0 511394 621056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 598980 0 0 0 609340 405779 562852 0 0 0 0 594912 +AADVETL(Xle->Asn)GDLVQFNKTDLLK MGYG000001346_01492;MGYG000002478_00772;MGYG000000013_02209;MGYG000004763_00952;MGYG000004876_02791;MGYG000003681_02079;MGYG000000243_01944;MGYG000000098_01975;MGYG000001378_05000;MGYG000004185_01136;MGYG000001370_01722 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,4AKBJ@815|Bacteroidaceae 0.8181818181818182 976|Bacteroidetes 1.0 K 0.9090909090909091 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 0.9090909090909091 rpoA 0.9090909090909091 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 0.9090909090909091 2.7.7.6 0.9090909090909091 ko:K03040 0.9090909090909091 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 0.9090909090909091 M00183 0.9090909090909091 R00435,R00441,R00442,R00443 0.9090909090909091 RC02795 0.9090909090909091 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 0.9090909090909091 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_01492 0.09090909090909091 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 0.9090909090909091 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 0.9090909090909091 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16623983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2174050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15114788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADVETLGDLVQFNK MGYG000002275_02090;MGYG000001306_02687;MGYG000002281_02248;MGYG000002935_01266;MGYG000000224_00448;MGYG000000243_01944;MGYG000001378_05000;MGYG000002560_00263;MGYG000001599_01824;MGYG000004185_01136;MGYG000001337_03861;MGYG000001346_01492;MGYG000000105_02032;MGYG000000054_03885;MGYG000002478_00772;MGYG000000013_02209;MGYG000002293_00479;MGYG000004763_00952;MGYG000004876_02791;MGYG000003681_02079;MGYG000001433_02303;MGYG000000098_01975;MGYG000002933_02108;MGYG000003312_02964 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,4AKBJ@815|Bacteroidaceae 0.7083333333333334 976|Bacteroidetes 1.0 K 0.9166666666666666 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 0.9166666666666666 rpoA 0.9166666666666666 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 0.9166666666666666 2.7.7.6 0.9166666666666666 ko:K03040 0.9166666666666666 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 0.9166666666666666 M00183 0.9166666666666666 R00435,R00441,R00442,R00443 0.9166666666666666 RC02795 0.9166666666666666 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 0.9166666666666666 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 0.9166666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002275_02090 0.041666666666666664 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 0.9166666666666666 0.9166666666666666 0.9166666666666666 0.9166666666666666 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 0.9166666666666666 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 0.9166666666666666 none 1.0 1661139 1427594 1703241 2014897 1410357 1457056 2629494 1238740 2062829 1267905 2402507 1599589 1563830 1235366 1126715 1963027 1663315 1386881 1286523 1287356 1503875 1122321 1633767 1776169 1169594 1362664 1812003 1313810 1860047 1980171 2177410 1246141 2259540 1818395 1542606 2121102 1484698 2075032 2813504 0 0 0 3045697 0 3837197 4316518 3227251 3836905 4887668 4658937 0 3876035 3448565 3987633 3663680 4051883 0 0 0 0 5568981 3026502 3829542 4168736 3602440 3908524 0 0 2477024 3289540 0 2452745 2839241 0 3253803 2839759 1088478 888918 1212831 1182447 2599906 1687535 1857735 1121709 1720720 1016250 2505977 1506897 1543385 1533479 1240040 1445341 1214708 2703053 1113339 1163928 1376638 1133442 2464072 1859507 1054049 1524343 942041 2136565 1556212 1549755 1666070 1192756 1243075 1047843 1157960 1853162 1292317 1696414 970076 784633 1000508 680516 920355 949076 1102549 771957 736085 760485 1228721 1142587 1189498 735609 648800 1078805 788526 1336799 992786 818380 1408944 909998 1679748 963474 805701 980980 1040862 641782 805801 771955 672007 856333 1176315 934704 937766 1362552 827450 997088 1369442 971752 823799 1197349 2127267 1439212 1689058 1935197 1449041 531274 1957804 981968 2271740 846434 929907 2273247 1223538 3694035 1545735 2648420 925232 1552441 2891890 1492691 1843424 1954796 1547358 3192989 999989 1664635 1127238 1037470 473994 1745620 1785438 579246 1341249 1045430 +AADVETLGDLVQFNKTDLLK MGYG000001346_01492;MGYG000002478_00772;MGYG000000013_02209;MGYG000004763_00952;MGYG000004876_02791;MGYG000003681_02079;MGYG000000243_01944;MGYG000000098_01975;MGYG000001378_05000;MGYG000004185_01136;MGYG000001370_01722 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,4AKBJ@815|Bacteroidaceae 0.8181818181818182 976|Bacteroidetes 1.0 K 0.9090909090909091 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 0.9090909090909091 rpoA 0.9090909090909091 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 0.9090909090909091 2.7.7.6 0.9090909090909091 ko:K03040 0.9090909090909091 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 0.9090909090909091 M00183 0.9090909090909091 R00435,R00441,R00442,R00443 0.9090909090909091 RC02795 0.9090909090909091 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 0.9090909090909091 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_01492 0.09090909090909091 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 0.9090909090909091 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 0.9090909090909091 none 1.0 0 0 0 0 5971810 23126640 30428436 7544753 0 5179440 2634944 0 35650878 0 0 6825143 0 10598450 0 0 8628220 16858937 340743 25152816 23677746 0 0 2984021 0 8384357 46255796 37695527 5830280 0 0 0 0 53902430 0 0 2909845 0 36415431 23508006 26272209 5184509 0 12555897 47252967 0 10687349 0 0 47163625 0 0 0 0 0 26548914 11920805 20194093 29080196 0 0 51084 0 0 26043758 36783398 18778369 0 0 0 0 11615093 0 0 0 0 13342008 9781976 24702061 0 0 0 33587723 0 21384830 0 0 23496993 0 37343718 0 0 9347018 8733869 23821783 46771450 78659 0 0 8602158 0 487195 0 10814124 0 0 0 0 0 7146049 0 0 8567196 0 0 8031227 14898984 14124234 0 0 54351 0 138183 0 0 12536649 0 8863355 0 0 0 8181992 33632746 0 0 0 0 0 0 12893898 0 17574927 0 0 0 0 0 11259366 0 0 10417035 0 9598639 8699156 16586135 11103442 0 5187729 36117659 0 36183685 0 0 4517693 0 1437087 0 0 0 0 17474412 30600366 22281160 0 0 0 0 21463530 10459139 7954656 0 0 0 0 0 0 +AADVETLGELVK MGYG000002438_02235;MGYG000000138_02862;MGYG000000696_01636;MGYG000001489_02641;MGYG000002218_02493 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0202@1|root,COG0202@2|Bacteria,4NE8W@976|Bacteroidetes,2FM4P@200643|Bacteroidia,22XAK@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoA 1.0 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 1.0 2.7.7.6 1.0 ko:K03040 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02235 0.2 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03040:rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6] 1.0 none 1.0 0 0 350809 0 0 0 0 0 0 0 0 0 500242 0 0 0 0 0 0 0 488925 0 0 0 0 0 0 149054 0 377543 0 0 389491 0 0 0 0 346471 0 0 587778 0 0 0 0 0 0 0 0 0 757622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1602679 0 0 661178 0 0 0 0 627186 0 0 0 0 0 0 0 0 0 0 0 0 375017 0 0 0 0 0 0 0 605117 0 0 0 0 0 0 0 0 0 0 0 379460 0 0 0 0 477216 0 0 1128471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386736 0 0 4263693 0 482330 0 0 0 0 384146 0 2499160 0 0 1528315 0 0 0 0 843929 0 0 1542116 0 0 0 0 0 0 0 0 0 3033559 0 0 0 0 0 0 0 0 0 1425547 0 0 0 0 1423769 0 0 0 0 1568684 0 0 0 0 0 +AADVGADLVGK MGYG000002964_00576;MGYG000000127_05422;MGYG000002478_02415;MGYG000004642_01840;MGYG000003926_01060;MGYG000004769_01663;MGYG000003279_00415;MGYG000004899_01967;MGYG000000224_02069;MGYG000002067_00146;MGYG000004797_03435;MGYG000003311_01901;MGYG000001732_02364;MGYG000000400_02184;MGYG000002721_02306;MGYG000002143_00403;MGYG000001502_01055;MGYG000000146_02298;MGYG000001599_00722;MGYG000002727_01191;MGYG000000215_00358;MGYG000002246_00264;MGYG000001725_01369;MGYG000003681_01853;MGYG000004756_00108;MGYG000001500_00249;MGYG000002905_01531;MGYG000001780_04010;MGYG000004573_00484;MGYG000003802_01296;MGYG000000138_00647;MGYG000001429_01938;MGYG000000179_01304;MGYG000001657_00904;MGYG000003282_00044;MGYG000001714_03130;MGYG000000098_01325;MGYG000004663_01400;MGYG000001661_00238;MGYG000000038_02712;MGYG000000262_00960;MGYG000004658_02698;MGYG000004482_01395;MGYG000000121_00356;MGYG000003142_02543;MGYG000002540_01543;MGYG000004760_01159;MGYG000001447_00382;MGYG000000198_01375;MGYG000001666_00309;MGYG000002218_02851;MGYG000003558_00139;MGYG000000170_02041;MGYG000001616_01732;MGYG000000054_00158;MGYG000001389_02398;MGYG000001164_01682;MGYG000002944_02433;MGYG000003449_01590;MGYG000004667_04890;MGYG000001770_01042;MGYG000004263_01339;MGYG000004707_00909;MGYG000004885_00074;MGYG000001546_02682;MGYG000002455_01921;MGYG000003374_01704;MGYG000004720_00672;MGYG000003697_01769;MGYG000002229_02459;MGYG000000466_01166;MGYG000004479_01013;MGYG000000117_02105;MGYG000002794_01654;MGYG000001651_01344;MGYG000002717_00152;MGYG000004285_00137;MGYG000002673_01165;MGYG000003221_00731;MGYG000002926_01074;MGYG000001423_02271;MGYG000002737_00797;MGYG000004763_00680;MGYG000002082_01918;MGYG000000034_02196;MGYG000000198_03536;MGYG000004536_00590;MGYG000002720_01717;MGYG000000202_00737;MGYG000004727_01727;MGYG000000236_00786;MGYG000002033_00992;MGYG000002084_00244;MGYG000002212_02487;MGYG000001683_01956;MGYG000000735_01187;MGYG000000243_02430;MGYG000002156_00692;MGYG000001754_00461;MGYG000002171_00877;MGYG000001167_00090;MGYG000004847_00160;MGYG000000216_02379;MGYG000000733_00463;MGYG000003589_01348;MGYG000001311_00647;MGYG000002036_00419;MGYG000000071_02010;MGYG000000095_03614;MGYG000003701_01447;MGYG000000142_02080;MGYG000001576_02602;MGYG000001493_00044;MGYG000002315_01585;MGYG000002953_01954;MGYG000002945_02680;MGYG000001310_00146 domain d__Bacteria 1.0 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,4AKW4@815|Bacteroidaceae 0.18803418803418803 186801|Clostridia 0.5470085470085471 C 1.0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane 0.8376068376068376 hppA 1.0 - 1.0 3.6.1.1 1.0 ko:K15987 1.0 ko00190,map00190 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 3.A.10.1 1.0 - 1.0 - 1.0 H_PPase 0.5726495726495726 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002964_00576 0.008547008547008548 inorganic diphosphatase. pyrophosphate phosphohydrolase. Specificity varies with the source and with the activating metal ion.-!-The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9. cf. EC 7.1.3.1. diphosphate + H2O = H(+) + 2 phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation 1.0 K15987:hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1] 1.0 none 1.0 4556785 3655282 2940601 3996882 3553834 4139419 3638943 3920894 3783655 3962467 3202024 3976094 2963096 4184894 4650874 3843381 4508943 3431874 4182792 4834594 4825418 4098488 3742011 3559561 4155171 4880447 4168147 3616827 4364546 3940466 3000113 3980776 3421268 4141721 4488420 4218330 4284991 3507244 4072972 2668196 2608641 3453289 3081845 2261802 3728753 3976997 2453051 3592332 2476937 3207953 2796808 0 0 2292654 3717724 2804685 3199766 3532095 3064447 1829237 2286011 2559383 3155383 3212411 3430985 2463020 3912890 2525909 3686713 0 2789956 3892083 0 4070604 3300974 3077308 6124344 3916413 4667246 5647184 4151903 3729945 4899064 5080374 4696782 5287171 3107727 3268988 3615366 4722904 5342154 4323217 5495217 4652920 5386374 5693130 4730723 4418872 4171008 3744885 5267721 4565801 5418234 3887081 5143740 4528175 3910528 4503974 3885473 4971455 3288273 5174632 5607471 4131123 3672143 3408527 4150182 3622478 3553709 3943649 3938468 3489177 3697184 4651279 2837602 3071408 2536048 3927867 3706795 3020615 5195859 6397204 3804514 4120529 3011108 3714132 5792284 4448670 3799100 3594566 3677667 6025124 4981682 3204175 2939358 3080950 4495932 3058647 3875035 4153386 3435534 4602702 0 2332545 2681887 0 2843408 2742771 3164457 3885952 3177451 3039220 1796584 2974892 2020612 0 2541474 2595340 3193781 3865471 3088166 0 2640249 0 3415678 2549821 2412969 2707959 2525377 3358697 4871528 3139127 2512051 2272053 1969740 2448850 2494147 2169669 3200587 3019018 +AADVGADLVGKVEAGIPEDDPR MGYG000002964_00576;MGYG000000127_05422;MGYG000001500_00249;MGYG000002478_02415;MGYG000004642_01840;MGYG000002084_00244;MGYG000001780_04010;MGYG000002212_02487;MGYG000001683_01956;MGYG000004707_00909;MGYG000004769_01663;MGYG000003279_00415;MGYG000000179_01304;MGYG000000243_02430;MGYG000004899_01967;MGYG000000224_02069;MGYG000004720_00672;MGYG000000098_01325;MGYG000004797_03435;MGYG000002229_02459;MGYG000001661_00238;MGYG000000038_02712;MGYG000004479_01013;MGYG000000117_02105;MGYG000003589_01348;MGYG000000262_00960;MGYG000001311_00647;MGYG000002036_00419;MGYG000002717_00152;MGYG000002143_00403;MGYG000001502_01055;MGYG000002926_01074;MGYG000003701_01447;MGYG000000198_01375;MGYG000004763_00680;MGYG000001666_00309;MGYG000002727_01191;MGYG000000198_03536;MGYG000004536_00590;MGYG000001576_02602;MGYG000002720_01717;MGYG000003681_01853;MGYG000001493_00044;MGYG000004727_01727;MGYG000000236_00786;MGYG000002953_01954;MGYG000000054_00158;MGYG000001616_01732 domain d__Bacteria 1.0 COG3808@1|root,COG3808@2|Bacteria,4NF2I@976|Bacteroidetes,2FM7F@200643|Bacteroidia,4AKW4@815|Bacteroidaceae 0.2916666666666667 186801|Clostridia 0.5625 C 1.0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane 0.8958333333333334 hppA 1.0 - 1.0 3.6.1.1 1.0 ko:K15987 1.0 ko00190,map00190 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 3.A.10.1 1.0 - 1.0 - 1.0 H_PPase 0.5833333333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002964_00576 0.020833333333333332 inorganic diphosphatase. pyrophosphate phosphohydrolase. Specificity varies with the source and with the activating metal ion.-!-The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9. cf. EC 7.1.3.1. diphosphate + H2O = H(+) + 2 phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation 1.0 K15987:hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1] 1.0 none 1.0 697044 649380 764064 648587 614980 714218 855364 921023 1024715 1036593 809455 1155030 0 0 832960 657911 1011888 773698 836335 710774 751775 622217 1102118 758737 934569 748162 756156 708971 1633971 850872 844670 709339 787934 606060 0 874940 724327 590305 450087 632690 348459 452263 503598 704917 363941 674515 398360 2117320 629079 415094 0 0 533900 484371 332018 297195 415324 557209 577873 419240 498933 580642 2087383 482676 702428 613615 3599784 921030 706399 502788 353678 314274 0 394191 389517 477500 988724 655272 1229040 1136639 1113573 1521599 940916 1179219 804765 977440 1392068 1353263 0 0 1322258 948413 931020 750261 1143028 1381408 853126 850111 650780 683867 1088392 525771 682553 706738 1647099 987516 1045864 968097 926904 1010528 0 1134383 1102397 856491 816727 626885 886636 821336 584827 750707 629754 698277 579051 522181 611037 348387 0 0 589528 660914 1111070 987785 830323 301784 840494 718002 425007 605391 582119 620856 387591 563031 0 637575 614235 705288 944658 376699 0 727299 534215 763990 732428 0 0 980736 541554 570774 738951 281955 820041 150516 0 285886 0 0 926247 0 191688 333925 495935 1344616 381222 0 378922 104622 458065 786222 196286 406377 1027489 393374 232054 205852 0 0 0 572564 440834 0 +AADVIVGAK MGYG000001714_01518 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus_A|s__Coprococcus_A catus|m__MGYG000001714 1.0 COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,27IU1@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 CH 1.0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 1.0 pyrK_1 1.0 - 1.0 1.18.1.2,1.19.1.1 1.0 ko:K00528,ko:K16951 1.0 ko00920,ko01120,map00920,map01120 1.0 - 1.0 R00858,R10146,R10159 1.0 RC00065 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001714_01518 1.0 ferredoxin--NADP(+) reductase. | flavodoxin--NADP(+) reductase. FPR. In chloroplasts and cyanobacteria the enzyme acts on plant-type [2Fe- 2S] ferredoxins, but in other bacteria it can also reduce bacterial 2[4Fe-4S] ferredoxins and flavodoxin.-!-Formerly EC 1.6.7.1 and EC 1.6.99.4. | This activity occurs in some prokaryotes and algae that possess flavodoxin, and provides low-potential electrons for a variety of reactions such as nitrogen fixation, sulfur assimilation and amino acid biosynthesis.-!-In photosynthetic organisms it is involved in the photosynthetic electron transport chain.-!-The enzyme also catalyzes EC 1.18.1.2. H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]. | NADP(+) + reduced [flavodoxin] = 2 H(+) + NADPH + oxidized [flavodoxin]. 1.0 1.0 1.0 1.0 Sulfur metabolism|Microbial metabolism in diverse environments 1.0 K00528:fpr; ferredoxin/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]|K16951:asrB; anaerobic sulfite reductase subunit B 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1179740 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADVKDISER MGYG000000271_02507;MGYG000004271_00779 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9,2.7.9.2 1.0 ko:K01007,ko:K08483 1.0 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060 1.0 M00173,M00374 1.0 R00199 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02507 0.5 phosphoenolpyruvate--protein phosphotransferase. | pyruvate, water dikinase. sugar--PEP phosphotransferase enzyme I. | pyruvate,water dikinase. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. | ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Phosphotransferase system (PTS) 1.0 K01007:pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2]|K08483:ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADVKDITDR MGYG000000255_01177 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3XZ65@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9,2.7.9.2 1.0 ko:K01007,ko:K08483 1.0 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060 1.0 M00173,M00374 1.0 R00199 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01177 1.0 phosphoenolpyruvate--protein phosphotransferase. | pyruvate, water dikinase. sugar--PEP phosphotransferase enzyme I. | pyruvate,water dikinase. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. | ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Phosphotransferase system (PTS) 1.0 K01007:pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2]|K08483:ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADVLR MGYG000001315_01867;MGYG000001619_00422 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.5 186801|Clostridia 1.0 C 0.5 electron transfer flavoprotein 0.5 etfB 0.5 - 1.0 - 1.0 ko:K03521 0.5 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.5 - 1.0 - 1.0 - 1.0 ETF 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01867 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.5 none 1.0 0 2998083 0 0 0 0 0 0 0 0 3948432 3736029 0 0 0 0 0 0 0 0 0 0 0 0 0 3952516 0 0 0 0 0 0 0 0 0 0 0 0 2665097 3759281 0 0 0 0 0 3438079 0 0 0 1757730 0 0 2962669 0 0 0 0 0 0 0 0 0 0 0 2724385 0 0 2484977 0 2884821 0 3627425 3882263 3088966 0 0 0 0 0 0 0 0 0 1989849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1666219 0 0 0 0 0 0 2894336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2025682 0 0 0 0 0 0 3325670 0 0 0 0 3983587 +AADVNPDTR MGYG000000262_00177 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,25WK3@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 - 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_00177 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02952:RP-S13, rpsM; small subunit ribosomal protein S13 1.0 none 1.0 0 0 0 521308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1915215 3106143 0 5906924 0 0 0 0 0 0 0 0 0 1617715 0 0 0 0 0 0 0 0 0 0 0 2405834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADVTPEQADEMGMK MGYG000002775_00885;MGYG000003266_00117;MGYG000002065_01444;MGYG000002919_01729;MGYG000001642_01358;MGYG000000188_00186 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CUI3@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Arginyl-tRNA synthetase 1.0 argS 1.0 - 1.0 6.1.1.19 1.0 ko:K01887 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03646 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002775_00885 0.16666666666666666 arginine--tRNA ligase. arginyl-tRNA synthetase. - ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01887:RARS, argS; arginyl-tRNA synthetase [EC:6.1.1.19] 1.0 none 1.0 0 539714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1569210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADWFK MGYG000004763_01074 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG4659@1|root,COG4659@2|Bacteria,4NQFX@976|Bacteroidetes,2G2KC@200643|Bacteroidia,4AW04@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 FMN_bind 1.0 rnfG 1.0 - 1.0 - 1.0 ko:K03612 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004763_01074 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03612:rnfG; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 540053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 562715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 544994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADWVIDHSTIEEK MGYG000001255_02250;MGYG000001300_01811 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001255_02250 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 181054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADYC(Carbamidomethyl)AQQAQQLR MGYG000002926_01306 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,2N6YH@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 - 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000002926_01306 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01868:TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410291 0 0 587379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424084 0 0 0 0 531388 575462 0 0 0 0 0 0 0 496129 0 773454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADYEKLQDSAASAAAR MGYG000003694_00128 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter faecis|m__MGYG000003694 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_00128 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 873598 0 0 0 0 884442 0 0 0 0 665277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADYEKLQSSVSSAAAR MGYG000002492_01471 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01471 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 419782 0 0 0 0 234299 0 0 0 0 214057 0 0 0 0 147791 0 130511 0 0 0 0 374416 0 416493 269928 878139 0 157944 0 0 293519 631142 213410 258772 255776 0 271078 0 1184732 0 312594 0 0 283401 0 225508 0 230115 664188 0 0 499318 221403 528241 305585 313490 0 291098 1009955 619234 856699 3237445 761769 1375215 753242 374295 0 0 770313 1458674 1428809 1361089 520568 0 1907092 575459 446674 0 485592 0 744193 789844 772485 562516 683848 665826 1619407 0 0 1369481 1039631 3507439 823354 1018114 0 676382 2465109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305618 0 0 0 0 0 0 0 0 0 0 164946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AADYIVTGQWAK MGYG000000179_00718 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,21Y18@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_00718 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Vitamin B6 metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00831:serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040851 0 0 0 0 0 0 0 0 0 +AAE(Glu->Asp)ELGVTYK MGYG000000200_00369 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp003471165|m__MGYG000000200 1.0 COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000200_00369 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4064986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2062269 0 0 4541382 0 0 0 0 0 3992275 0 0 0 3140324 0 3577869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3160471 0 0 0 3899388 0 0 0 0 0 0 0 0 1840441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAE(Glu->Gln)AYFLLAEAK MGYG000002478_01404;MGYG000004797_04332 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01404 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1844730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEA(Ala->Ser)YFLLAEAK MGYG000002478_01404;MGYG000004797_04332 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01404 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 703978 731798 0 0 617800 696349 0 0 0 0 0 676349 0 0 0 2415591 0 0 0 0 2756253 0 0 0 0 2326709 0 0 0 0 568417 0 710204 471649 0 600125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 807569 0 0 0 0 0 0 123674 0 0 0 +AAEAAAALKPGEALMLENLR MGYG000001415_01540 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_01540 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 700560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 661551 772076 0 0 0 0 0 0 813621 0 776818 556431 0 124271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 235640 145274 0 0 0 0 0 0 177631 0 141586 122920 0 275905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175929 170047 0 0 0 0 0 0 405202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89243 0 654508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 710224 611492 0 0 0 0 0 0 157541 0 668532 192707 0 +AAEAAAKAEAEAANAPAEEAPAAET(Thr->Ala)TEAPAEA MGYG000002478_03159 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_03159 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1136141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 779670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAAAKAEAEAANAPAEEAPAAETT(Thr->Ala)EAPAEA MGYG000002478_03159 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_03159 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAAAKAETEAAATEEAPAAEATEAPAEA MGYG000000243_01032 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01032 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 906015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1057092 0 0 0 0 740529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAAAPAQGGK MGYG000000179_00066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1744@1|root,COG1744@2|Bacteria,1U4NN@1239|Firmicutes,24CRY@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Basic membrane protein 1.0 - 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_00066 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07335:bmpA, bmpB, tmpC; basic membrane protein A and related proteins 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 120933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23071052 10559520 16238200 24159910 6598863 5293968 7857731 6028035 21725922 39125918 14884511 18255547 4867483 42112877 22669790 12467353 13408786 0 18241027 10450783 17248894 7842461 0 12939603 26787473 30333739 32359668 0 39619138 6572776 17719340 7618384 23845339 14541369 9182011 30977864 20965905 16295809 +AAEAAAPAQGGK(Cation_Na) MGYG000000179_00066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1744@1|root,COG1744@2|Bacteria,1U4NN@1239|Firmicutes,24CRY@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Basic membrane protein 1.0 - 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_00066 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07335:bmpA, bmpB, tmpC; basic membrane protein A and related proteins 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1241521 0 0 0 0 0 0 616527 0 0 0 0 +AAEAAAQAQNAK MGYG000001780_04661 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__|m__MGYG000001780 1.0 COG0845@1|root,COG0845@2|Bacteria,4NECC@976|Bacteroidetes,2FMDD@200643|Bacteroidia,4ANZR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Auxiliary transport protein, membrane fusion protein (MFP) family protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01993 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001780_04661 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01993:ABC-2.TX; HlyD family secretion protein 1.0 none 1.0 639491 0 0 0 0 0 975955 641994 0 722574 1901239 695314 403841 744134 687181 0 659917 0 656312 0 0 0 0 0 761471 868187 931259 0 736375 841268 774480 0 0 922474 0 840608 615369 0 322942 0 0 0 0 0 173291 306634 0 278223 1057349 404798 203076 299776 185618 0 247760 0 231638 0 0 0 0 0 235646 295806 403670 0 307192 258281 0 0 0 181901 0 256608 184212 0 0 0 0 0 0 0 0 0 0 0 262360 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111006 0 0 0 0 0 0 0 223932 0 0 0 0 0 259360 135883 0 168497 658025 224715 141954 234971 250771 0 0 0 252079 0 0 0 0 0 145152 443744 217475 0 217564 147089 230055 0 0 255448 0 101407 157886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184774 0 0 0 0 0 0 199265 0 0 0 0 0 0 0 0 0 146896 0 0 +AAEAAAQAQNEK MGYG000004748_01973;MGYG000000013_03125;MGYG000004019_01965;MGYG000000098_01923;MGYG000001661_00289;MGYG000000196_04115;MGYG000002281_00036;MGYG000000054_01911;MGYG000002549_00068;MGYG000001313_03010;MGYG000003351_04331;MGYG000001378_03174;MGYG000002455_03725;MGYG000000105_01451;MGYG000003681_01202;MGYG000001337_04184;MGYG000000236_02897;MGYG000003922_01651;MGYG000000029_01174 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0845@1|root,COG0845@2|Bacteria,4NECC@976|Bacteroidetes,2FMDD@200643|Bacteroidia,4ANZR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Auxiliary transport protein, membrane fusion protein (MFP) family protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01993 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004748_01973 0.05263157894736842 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01993:ABC-2.TX; HlyD family secretion protein 1.0 none 1.0 400954 305328 423683 574068 0 350257 0 494092 720664 678098 305483 834740 267174 0 632553 474716 521071 0 0 616170 503638 457240 0 517853 515541 692409 0 0 508942 658780 0 0 528343 721412 0 461519 366653 306380 889906 558481 786568 1154319 0 966078 0 1239580 1101435 1499598 1432987 1013823 542965 0 1019842 716719 974419 0 0 1005927 1010217 1253856 0 817394 1020301 1272666 0 0 1033501 1150941 0 0 518969 850055 0 757237 1150916 788377 352042 546442 651895 564606 0 738384 0 553419 638428 552357 529327 643297 523136 0 0 535369 577191 0 0 473139 692647 474359 0 558050 446767 502327 0 0 519215 501666 0 0 429323 612919 0 799959 689250 617221 672775 580553 608184 492224 0 617297 0 645936 532164 500153 469847 617661 538545 0 525761 579325 636645 0 0 585758 362865 496537 0 553155 889418 1058603 0 0 627811 470806 0 0 530249 529795 0 451285 670528 525997 734838 328089 544435 665549 0 528928 0 592373 798858 502516 921153 569160 829476 0 635908 555762 439199 0 0 687417 491380 631045 0 433257 734751 1007775 0 0 541245 621345 0 0 0 574207 0 812371 742144 398934 +AAEAAGADIVGDDELIAK MGYG000001300_02637 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3WH4A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02637 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575296 0 0 0 0 0 0 0 0 0 373316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1734177 0 0 0 0 0 0 0 0 0 1507987 0 0 0 0 1529449 1867408 0 1556005 0 0 0 0 0 0 0 0 0 2094604 0 0 0 0 0 0 0 0 0 236608 0 0 0 0 0 0 0 0 0 162183 0 0 0 0 0 0 0 348551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAAGAQEVGDDDLIAK MGYG000003937_00914;MGYG000003921_01312;MGYG000004732_01000;MGYG000001157_02092;MGYG000000573_00679;MGYG000000084_00770 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3WH4A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_00914 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 1045893 1135759 977431 928074 1057513 1128796 891803 1371493 1149624 1375254 1228860 1651684 1600146 1150949 1154279 1321587 1218578 2538183 1200440 1240298 1183466 956456 1681487 982532 1322685 1177011 1004363 1942382 1405820 1078508 878885 1157088 595069 1092025 1299216 1063085 844956 804342 0 0 0 304890 0 97968 244644 0 238471 144980 148357 1419969 0 0 0 0 0 1178405 0 0 0 0 1461816 0 116444 0 0 1779479 0 1102961 0 0 0 0 237736 0 0 0 0 0 232875 0 0 0 0 0 545567 232482 302362 2946773 413592 318194 213557 0 473267 383935 0 292539 524354 0 289884 155981 560931 186367 395609 561499 0 0 543406 0 291837 276938 539626 423996 226518 0 439520 621890 588665 554566 490592 487643 649099 529885 513707 524814 416000 1560555 1003807 420531 559930 439987 397269 1584248 426991 466482 362763 517505 1334968 639330 576004 355362 500246 2178087 685577 782261 769597 457577 620073 203601 585951 0 0 616631 505761 609095 470892 632582 412197 434458 338315 782425 419617 208074 261632 1771913 619281 674828 498883 594527 692732 1946974 431238 304405 735560 479868 2423613 548624 559970 493132 549201 2887168 498993 718434 451420 459571 611445 615914 765982 599177 557835 560145 +AAEAAKAGAESTK MGYG000001617_03554 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp900547735|m__MGYG000001617 1.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Dihydroxyacetone kinase 1.0 dhaK 1.0 - 1.0 2.7.1.28,2.7.1.29,4.6.1.15 1.0 ko:K00863 1.0 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 1.0 M00344 1.0 R01011,R01059 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak1,Dak2,SDH_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001617_03554 1.0 triokinase. | glycerone kinase. | FAD-AMP lyase (cyclizing). triose kinase. | dihydroxyacetone kinase. | FMN cyclase. While FAD was the best substrate tested the enzyme also splits ribonucleoside diphosphate-X compounds in which X is an acyclic or cyclic monosaccharide or derivative bearing an X-OH group that is able to attack internally the proximal phosphorus with the geometry necessary to form a P=X product; either a five-atom monocyclic phosphodiester or a cis-bicyclic phosphodiester-pyranose fusion.-!-The reaction is strongly inhibited by ADP or ATP but is unaffected by the presence of the product, cFMN. ATP + D-glyceraldehyde = ADP + D-glyceraldehyde 3-phosphate + H(+). | ATP + dihydroxyacetone = ADP + dihydroxyacetone phosphate + H(+). | FAD = AMP + H(+) + riboflavin cyclic-4',5'-phosphate. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Glycerolipid metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|RIG-I-like receptor signaling pathway 1.0 K00863:DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 872229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAALQEAEQR MGYG000004271_01972;MGYG000000271_02740;MGYG000000404_01863 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0457@1|root,COG0457@2|Bacteria,1TY3C@1239|Firmicutes,248IE@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Psort location Cytoplasmic, score 1.0 SpoVK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_19,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_01972 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAAQEVIEDTAEEEQPAEQTAQ MGYG000001300_00870 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,3WKHQ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00870 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 206539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213073 0 1888177 1859480 0 0 1417916 0 0 0 0 0 961546 0 0 0 0 0 0 0 0 0 857318 0 1299324 0 0 0 0 0 0 0 0 2113119 0 0 0 0 2142537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAAYTGSQEPVEEMR MGYG000002438_01051 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,22VY5@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01051 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00812:aspB; aspartate aminotransferase [EC:2.6.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 924834 0 0 0 0 0 0 0 0 1114665 0 0 0 0 0 0 0 0 1081462 0 0 0 0 0 0 0 0 +AAEAAYTGSQEPVEEMRK MGYG000002438_01051 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,22VY5@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01051 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00812:aspB; aspartate aminotransferase [EC:2.6.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1441422 0 0 0 0 0 0 0 0 1296050 0 0 0 0 0 0 0 0 +AAEAAYTGTQAPVEEM(Oxidation)R MGYG000004823_01604;MGYG000002560_01853;MGYG000003693_02599;MGYG000002933_02482;MGYG000004748_02763;MGYG000002291_02904;MGYG000000781_00145;MGYG000001306_02803;MGYG000001835_00632;MGYG000002218_00765;MGYG000000243_01798;MGYG000004797_00034;MGYG000002171_02995;MGYG000002470_03292;MGYG000000042_00902;MGYG000003681_03182;MGYG000001787_02392 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004823_01604 0.058823529411764705 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00812:aspB; aspartate aminotransferase [EC:2.6.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAAYTGTQAPVEEMR MGYG000004823_01604;MGYG000002560_01853;MGYG000003693_02599;MGYG000002933_02482;MGYG000004748_02763;MGYG000002291_02904;MGYG000000781_00145;MGYG000001306_02803;MGYG000001835_00632;MGYG000002218_00765;MGYG000000243_01798;MGYG000004797_00034;MGYG000002171_02995;MGYG000002470_03292;MGYG000000042_00902;MGYG000003681_03182;MGYG000001787_02392 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004823_01604 0.058823529411764705 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00812:aspB; aspartate aminotransferase [EC:2.6.1.1] 1.0 none 1.0 1048409 1192450 3377838 1427018 1887757 1321728 1452487 943416 984489 778588 1005215 965258 3053606 925540 633031 1936485 1154281 1061760 1007971 907236 1069850 812689 1461177 1195208 874781 755389 1165026 1542822 0 1149049 2098095 1321940 2945816 864076 997416 1063402 833775 3204802 935180 747064 980458 1227842 1644218 880560 823545 1044878 756576 900593 1474555 1012593 3626941 1164776 1065340 2738382 861558 2052345 695274 854168 916836 1078584 3018083 776988 965456 1041508 914103 2008464 0 972748 878078 1298125 978734 932078 932833 1055527 956426 801815 405325 0 530404 538290 835994 516310 770466 332171 751864 372697 648998 587616 1463018 577119 486828 880165 408146 1205823 534849 418655 425866 459933 1026643 573687 470838 448027 360231 831725 0 354886 707631 0 217066 0 534291 796529 584413 586252 195952 0 0 0 0 575169 238810 0 0 0 0 540347 408909 0 0 327195 210866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431642 377555 0 0 0 0 640788 460703 186387 776211 1133921 943375 664008 575313 794919 267333 598689 831433 2832961 520565 679485 2387479 711280 2038882 592107 970977 454567 570061 1851236 1179914 985213 842917 631143 1644539 0 959948 913494 698217 531941 599131 805010 135668 1092246 708036 +AAEAAYTGTQAPVEEMRK MGYG000003693_02599;MGYG000000243_01798;MGYG000002171_02995;MGYG000003681_03182;MGYG000001306_02803 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_02599 0.2 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00812:aspB; aspartate aminotransferase [EC:2.6.1.1] 1.0 none 1.0 0 0 3208138 0 1086889 0 0 0 0 0 0 0 0 0 0 0 0 314032 0 0 0 0 387720 0 0 0 0 504260 0 0 1733894 0 3136881 0 0 0 0 2221820 0 0 472208 0 488249 0 0 0 0 0 0 0 0 0 0 0 0 863360 0 0 0 0 1276602 0 0 0 0 1003540 0 0 299514 0 381888 0 0 0 0 409576 0 0 152558 0 523676 0 0 0 0 0 0 0 0 0 0 0 0 545247 0 0 0 0 392532 0 0 0 0 461332 0 0 370636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 558311 0 0 0 0 0 0 0 0 0 0 0 0 385434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAAYTGTQEPVKEMQK MGYG000002549_04026;MGYG000002281_04838 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_04026 0.5 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00812:aspB; aspartate aminotransferase [EC:2.6.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314919 0 0 1198481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 665413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 895844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAAYTGTQVPVEEMR MGYG000001346_02469 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_02469 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00812:aspB; aspartate aminotransferase [EC:2.6.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 618857 316746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247201 676586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1093633 442954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355773 240005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1660733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAAYTLDQGAVEEMR MGYG000003697_01979;MGYG000002834_01610 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01979 0.5 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00812:aspB; aspartate aminotransferase [EC:2.6.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1108004 0 0 762349 0 0 0 0 820484 0 0 0 0 0 0 1172966 0 0 0 1306782 1410299 1119915 0 0 0 989841 0 0 0 0 946731 0 0 0 0 617885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEADAIVTIGGGSSMDTAK MGYG000003266_00960 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900762015|m__MGYG000003266 1.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CV1A@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 - 1.0 - 1.0 1.1.1.1,1.1.1.77 1.0 ko:K00001,ko:K00048 1.0 ko00010,ko00071,ko00350,ko00625,ko00626,ko00630,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00630,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00623,R00754,R01781,R02124,R02257,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 1.0 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003266_00960 1.0 alcohol dehydrogenase. | lactaldehyde reductase. aldehyde reductase. | propanediol oxidoreductase. Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | (1) (R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + H(+) + NADH. (2) (S)-propane-1,2-diol + NAD(+) = (S)-lactaldehyde + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Retinol metabolism|Metabolism of xenobiotics by cytochrome P450|Drug metabolism - cytochrome P450|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K00001:E1.1.1.1, adh; alcohol dehydrogenase [EC:1.1.1.1]|K00048:fucO; lactaldehyde reductase [EC:1.1.1.77] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 691572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEADC(Carbamidomethyl)IVTIGGGSSMDTAK MGYG000000084_00896;MGYG000000573_01786;MGYG000000022_00774;MGYG000003166_01233;MGYG000002545_02393;MGYG000003921_01948 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHER@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 fucO 1.0 - 1.0 1.1.1.77 1.0 ko:K00048 1.0 ko00630,ko00640,ko01120,map00630,map00640,map01120 1.0 - 1.0 R01781,R02257 1.0 RC00087,RC00099 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000084_00896 0.16666666666666666 lactaldehyde reductase. propanediol oxidoreductase. - (1) (R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + H(+) + NADH. (2) (S)-propane-1,2-diol + NAD(+) = (S)-lactaldehyde + H(+) + NADH. 1.0 1.0 1.0 1.0 Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Microbial metabolism in diverse environments 1.0 K00048:fucO; lactaldehyde reductase [EC:1.1.1.77] 1.0 none 1.0 0 0 326941 357263 0 309090 156191 0 0 0 512738 0 0 0 0 0 0 859616 440296 0 0 207966 950184 566855 0 522517 0 1206962 0 0 324351 0 326735 398897 0 368110 365311 373632 690477 0 699047 724619 0 801934 945531 0 0 0 508583 743450 0 0 0 0 893640 976017 787234 0 0 375164 1291062 610067 941545 628397 0 1154168 0 0 612772 0 733360 547671 0 631533 638742 349470 0 0 0 0 0 496692 500277 0 0 0 322820 260006 0 0 0 0 0 1878280 406756 0 0 0 1713776 0 0 272873 0 1749497 0 0 554118 0 0 537868 0 523090 392293 603932 581935 0 686496 458404 0 800876 704791 0 0 0 323637 712372 0 0 0 0 464409 1912087 444211 0 0 519187 2147568 639139 482273 512301 0 1302925 0 0 574636 0 664392 614019 0 384996 745711 533596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1287065 0 0 0 0 1735215 0 0 162141 0 1695706 0 0 0 0 280238 0 0 0 0 0 +AAEAEAAR MGYG000002775_01690;MGYG000003266_00923 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0254@1|root,COG0254@2|Bacteria,2HUWQ@201174|Actinobacteria,4CVW5@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Binds the 23S rRNA 1.0 rpmE 1.0 - 1.0 - 1.0 ko:K02909 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L31 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002775_01690 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02909:RP-L31, rpmE; large subunit ribosomal protein L31 1.0 none 1.0 0 148076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAEADAAK MGYG000000003_00520 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG2885@1|root,COG2885@2|Bacteria,4NNK8@976|Bacteroidetes,2FMJK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 M 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_00520 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1495589 782210 569642 1935302 0 983819 1577222 0 2402666 1425431 434278 1246578 0 1277297 0 0 0 0 2401585 1711223 2001888 897348 0 966114 1911592 2137036 0 0 1263621 1925820 0 791906 690033 0 1197004 1947617 1578480 436627 940556 498572 1007872 1263278 0 826575 1070545 0 907582 1064461 785793 0 0 1192865 0 0 0 0 1076195 814453 779618 825571 0 979234 896826 1247793 0 0 858042 926667 0 944562 420307 510531 759908 743861 920046 726987 795839 660385 949625 911860 0 406658 647755 0 949479 817333 583019 699648 0 698894 0 0 0 0 1255340 1494923 1604437 452671 0 544457 949452 752744 0 0 878091 1000053 0 440929 1034649 2008655 957723 1650299 1132210 955707 632147 699596 564285 890482 0 479253 971855 0 744616 610845 785988 927666 0 0 0 0 0 0 839057 803540 358372 518208 0 596305 785180 899428 0 0 663209 542018 0 525030 392533 869729 630850 300846 0 594894 0 299699 0 0 0 0 140054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88897 0 0 0 0 473398 0 0 0 +AAEAEAETIEDTSAQEA MGYG000002926_00849 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000431575|m__MGYG000002926 1.0 2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,2N7Q1@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_00849 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341889 0 0 0 0 0 254641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 860862 0 754190 0 0 0 0 0 750278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAEAPAEEAAEAEK(Xlink_BuUrBu[111][K](Nmethylmaleimide)AE MGYG000002469_01742 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium breve|m__MGYG000002469 1.0 COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4D0PZ@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Ribosomal protein L17 1.0 rplQ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 1.0 - 1.0 ko:K02879 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002469_01742 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02879:RP-L17, MRPL17, rplQ; large subunit ribosomal protein L17 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 619865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAEIPVFTVDR MGYG000003383_00664 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium scardovii|m__MGYG000003383 1.0 COG1879@1|root,COG1879@2|Bacteria,2GJ0Z@201174|Actinobacteria,4D2SP@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K02058,ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212,M00221 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003383_00664 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K02058:ABC.SS.S; simple sugar transport system substrate-binding protein|K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 590950 0 0 0 0 646350 0 0 0 0 601500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6600680 0 0 0 0 1891990 0 0 0 0 4818935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309600 0 0 0 0 0 0 0 0 0 1309439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAEKTEDAE MGYG000000022_01173;MGYG000000195_01312 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01173 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332067 0 0 184876 0 1092521 0 0 0 0 1742774 0 0 0 0 2164881 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381140 412433 0 356785 0 341094 0 0 0 0 984536 0 0 0 0 1714308 0 0 382669 0 0 585748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75967 0 0 0 0 499035 0 0 0 0 0 0 0 0 0 550773 0 0 209489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343622 229949 0 247997 0 2443835 0 0 0 0 3235536 0 0 0 0 1407632 0 0 393018 0 0 200537 0 0 0 0 +AAEAEKTEDAQ MGYG000002545_00080 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_G|m__MGYG000002545 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002545_00080 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1793453 0 0 0 0 1233524 0 0 0 0 1826159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15454 0 0 0 0 135420 0 0 0 0 422277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335537 0 0 0 0 279337 0 0 0 0 158777 0 0 0 0 0 0 0 0 0 0 +AAEAEVDALVK MGYG000003683_01140 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01140 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]|K15515:sauS; sulfoacetaldehyde dehydrogenase [EC:1.2.1.81] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1248309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2674209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2877135 0 805862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732931 0 0 0 0 0 0 0 0 0 0 0 0 1094550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1030568 0 0 0 0 0 0 0 0 0 0 1161728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAFAELLK MGYG000002455_04253 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG0614@1|root,COG0614@2|Bacteria,4NGP1@976|Bacteroidetes,2FNKG@200643|Bacteroidia,4AMD2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_04253 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1818694 0 0 0 0 1261539 0 0 0 0 1486335 0 0 0 0 0 0 0 0 0 0 +AAEAIGK MGYG000001157_01952 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540775|m__MGYG000001157 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001157_01952 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94679 0 0 0 0 49064 0 0 0 0 1307075 0 0 0 0 0 0 0 0 0 0 +AAEAIGKGLAASPGSAC(Carbamidomethyl)GR MGYG000000084_02524;MGYG000004732_02304 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000084_02524 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEALKER MGYG000002515_01689;MGYG000003372_04360;MGYG000002494_03245;MGYG000002477_02881 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0462@1|root,COG0462@2|Bacteria,1MW21@1224|Proteobacteria,1RMUC@1236|Gammaproteobacteria,3XP2G@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) 1.0 prs 1.0 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iAF1260.b1207,iAPECO1_1312.APECO1_323,iB21_1397.B21_01192,iBWG_1329.BWG_1032,iE2348C_1286.E2348C_1330,iEC042_1314.EC042_1264,iEC55989_1330.EC55989_1303,iECABU_c1320.ECABU_c14780,iECBD_1354.ECBD_2414,iECB_1328.ECB_01182,iECDH10B_1368.ECDH10B_1260,iECDH1ME8569_1439.ECDH1ME8569_1146,iECD_1391.ECD_01182,iECED1_1282.ECED1_1355,iECH74115_1262.ECH74115_1688,iECIAI1_1343.ECIAI1_1228,iECIAI39_1322.ECIAI39_1543,iECNA114_1301.ECNA114_1372,iECO103_1326.ECO103_1309,iECO111_1330.ECO111_1536,iECO26_1355.ECO26_1720,iECOK1_1307.ECOK1_1360,iECP_1309.ECP_1255,iECS88_1305.ECS88_1275,iECSE_1348.ECSE_1257,iECSF_1327.ECSF_1183,iECSP_1301.ECSP_1597,iECUMN_1333.ECUMN_1504,iECW_1372.ECW_m1293,iECs_1301.ECs1712,iEKO11_1354.EKO11_2647,iETEC_1333.ETEC_1311,iEcDH1_1363.EcDH1_2440,iEcE24377_1341.EcE24377A_1355,iEcHS_1320.EcHS_A1312,iEcSMS35_1347.EcSMS35_1935,iEcolC_1368.EcolC_2419,iG2583_1286.G2583_1478,iJO1366.b1207,iJR904.b1207,iLF82_1304.LF82_1744,iNRG857_1313.NRG857_06180,iSBO_1134.SBO_1860,iSDY_1059.SDY_1256,iSSON_1240.SSON_1971,iUMN146_1321.UM146_11025,iUMNK88_1353.UMNK88_1523,iUTI89_1310.UTI89_C1401,iWFL_1372.ECW_m1293,iY75_1357.Y75_RS06300,ic_1306.c1665 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_01689 0.25 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00948:PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEALLLTK MGYG000000133_00484;MGYG000002966_02815 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1142@1|root,COG1142@2|Bacteria,1VCTD@1239|Firmicutes,24EHU@186801|Clostridia,25XTU@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 4Fe-4S dicluster domain 1.0 - 1.0 - 1.0 - 1.0 ko:K05796 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Fer4,Fer4_10,Fer4_3,Fer4_4,Fer4_6,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00484 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K05796:hydN; electron transport protein HydN 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 662588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1041999 0 0 0 0 306641 +AAEAPAAEAKPARK MGYG000000022_00261 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 2BACE@1|root,323SU@2|Bacteria,1UH7E@1239|Firmicutes,257YA@186801|Clostridia,3WKG9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00261 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 51275 0 0 0 0 151623 0 0 0 0 120195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144798 0 0 0 0 225307 0 0 0 0 213785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEASLMSAR MGYG000000196_03104;MGYG000001378_04950 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,2FND5@200643|Bacteroidia,4AKYA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 MU 1.0 Efflux transporter, outer membrane factor lipoprotein, NodT family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OEP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_03104 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEASYQANDEVNALK MGYG000000243_03195 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF4@976|Bacteroidetes,2G3EZ@200643|Bacteroidia,4APQM@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03195 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754578 0 0 0 0 0 0 0 1095062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEATK(Lys->Gln)LFVEGK MGYG000001300_00595 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,3WJGA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00595 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2007068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2501939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10051390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEATQLFVEGK MGYG000000022_00316 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,3WJGA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 COG COG1879 ABC-type sugar transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00316 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 2028396 0 0 1684662 0 0 0 0 0 0 0 0 0 0 0 2775062 0 1255752 0 0 2425771 0 0 1435546 1402869 2520753 0 0 0 1414906 0 0 0 0 0 1453569 3426313 0 2486460 0 0 2908400 0 0 0 0 0 0 0 0 0 0 0 9662987 0 3142161 0 2650514 8761213 2912245 0 2999689 3245683 9285551 0 0 1872957 3091240 2599760 0 0 0 3585699 2338077 2843698 0 1650122 0 0 2285598 0 0 0 0 0 0 0 0 0 0 0 9318118 0 1720685 0 2941827 0 2380164 0 3254438 2433678 12690592 0 0 2562355 2865229 2057713 0 3342741 0 3267993 2572692 0 0 2744649 0 0 3436892 0 0 0 0 0 0 0 0 0 0 0 2673567 0 1429292 0 3304881 3174663 0 0 912877 886292 3705959 0 0 2317599 1883176 1906445 0 1160791 0 0 2831173 955495 0 0 0 0 561136 0 0 0 0 0 0 0 0 0 0 0 1604521 0 576050 0 939720 584029 0 0 773875 0 620909 0 0 1060204 674714 944428 0 298675 0 295676 793815 +AAEAVAAVEPGK MGYG000002557_00596;MGYG000004875_00024;MGYG000002050_01271;MGYG000000188_00828;MGYG000003073_01053;MGYG000004396_00611;MGYG000004746_01527;MGYG000001636_00874;MGYG000003274_01602;MGYG000003851_00622;MGYG000004681_01192;MGYG000002919_00267;MGYG000002775_01123;MGYG000002970_00370;MGYG000000802_01544 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CUGT@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002557_00596 0.06666666666666667 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 650672 4222079 641619 347983 0 711637 205919 1014289 449726 989061 1548404 1053278 2721318 0 1251591 3162222 536359 2039732 719889 923165 776738 839388 1131640 0 0 484358 477526 1501311 1186006 592781 619040 0 553557 0 646420 507452 557971 545127 897853 774722 363861 744006 0 444154 832539 826749 666109 524991 1474494 591049 1159080 0 268359 653904 371293 1909550 615450 845487 484323 0 1054833 797464 0 601746 776505 1753420 941200 582709 1068792 0 0 0 481712 1050409 880057 405060 1139286 1334015 275704 696916 0 319267 812534 1088531 500921 940660 648543 534685 1559851 0 1149733 2000023 1793509 349310 1034682 1165184 926875 1188451 859856 0 0 884296 1130064 1036375 842395 803928 365976 0 1060264 0 667851 384485 688095 484122 975120 1595754 1393663 1757578 0 1287690 1460319 623184 934041 1719135 5160820 1445803 6525824 0 0 9049002 2131925 1300058 785372 1753193 672526 3161518 388114 2465558 0 0 858673 2505913 4817415 2579103 2089615 0 1435688 0 514853 903773 381465 2205957 0 362825 0 605017 0 0 0 0 0 0 696384 0 0 0 0 161197 0 0 271538 0 0 0 159584 0 0 0 0 521326 529686 0 0 0 372032 0 0 0 0 0 +AAEAVAAVEPGKVLVLENVR MGYG000001636_00874;MGYG000002919_00267;MGYG000001718_00620;MGYG000002775_01123;MGYG000002050_01271;MGYG000000188_00828 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CUGT@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001636_00874 0.16666666666666666 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191084 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 377780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAVN(Deamidated)GSLSGTK MGYG000000077_01499;MGYG000000262_00355 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG3087@1|root,COG4577@1|root,COG3087@2|Bacteria,COG4577@2|Bacteria,1VEIA@1239|Firmicutes,24JTP@186801|Clostridia,25XFB@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_01499 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 872860 971155 829712 466535 0 1112276 0 955090 740632 934681 676511 0 980896 941364 1109061 1117799 618999 0 1239479 1091581 585235 1229033 0 272146 2173760 422422 265864 0 0 503558 0 994935 164016 627041 344832 0 409748 572542 744245 868259 212194 459635 0 599827 1351405 481338 635258 451558 194183 0 411485 419496 456936 150031 390756 0 603795 776294 127763 282488 0 840830 504669 510549 581871 0 0 226364 0 381650 318597 686065 726560 0 771465 296131 2705065 3072187 586251 3017121 0 813962 684131 2281380 914608 2157458 473482 0 1778643 794004 2350299 2022363 1894162 0 2915375 2672608 1951456 3019117 0 1176425 2752865 1731091 2882371 0 0 1585301 0 2202698 1376017 2340546 2544378 0 1702861 693154 1288775 1377926 934669 882347 0 1680864 2021929 1130887 1018178 1776321 948387 0 1226685 1498163 850780 1942939 1411475 0 617792 1710604 497782 1587794 0 1056957 867371 521297 1310011 0 0 1358628 0 671060 1208791 601444 1389410 0 961567 836947 1004561 1425935 1644230 755196 0 1067830 860087 1091697 1067738 1308730 1343676 0 1771117 985640 1221724 1676809 933392 0 987789 998121 810842 1264865 0 713926 1277841 1251222 779874 0 0 964491 0 1238540 1525874 1193152 67263 0 1482072 1359804 +AAEAVNGSLSGTK MGYG000000077_01499;MGYG000000262_00355 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG3087@1|root,COG4577@1|root,COG3087@2|Bacteria,COG4577@2|Bacteria,1VEIA@1239|Firmicutes,24JTP@186801|Clostridia,25XFB@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_01499 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 510418 646869 451362 0 0 724503 0 0 0 0 600532 0 1067539 0 445259 1102238 0 0 0 571206 579109 1137112 0 227748 0 504762 0 0 419869 0 0 480275 0 0 0 0 378978 555777 666276 500377 0 433084 0 0 0 0 0 0 0 0 0 0 221683 0 0 0 0 485067 110688 0 0 612369 0 201270 0 0 532956 0 0 116177 0 0 0 0 210067 595857 1561567 1957869 666116 2291776 0 1437595 0 0 0 0 1278332 0 1062866 0 1913349 1363137 0 0 0 2195729 1503967 2081942 0 1147686 0 1614759 0 0 1003457 0 0 1081071 1268582 0 0 0 1259769 872007 909888 848669 782782 1102709 0 928012 0 0 0 0 764579 0 899150 0 658447 1366241 0 0 0 1212370 415975 878543 0 860118 0 0 0 0 823887 0 0 714777 1018582 0 0 0 0 953771 0 1413178 994752 699565 0 858860 0 0 0 0 980691 0 1213875 0 465526 1240747 0 0 0 1246576 0 946836 0 697208 0 959883 0 0 199640 0 0 957435 1107588 0 0 0 825132 873312 +AAEAYFLLAEAK MGYG000002478_01404;MGYG000004797_04332 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01404 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2513704 2841745 2927951 2871290 2006747 2241182 3295133 1812232 2747020 2019244 2741024 2615209 1835897 2116001 1561793 2935493 2553017 0 2553551 2178916 2191908 2196917 0 3133315 2449494 2669159 2388285 0 3415768 2502734 5289368 3496486 2726058 961172 3616019 3086318 2617688 2290236 469370 659308 834100 389650 732152 910189 903066 453830 557791 768286 499666 714394 0 790291 1183722 617128 320436 0 813723 733683 875241 901213 0 590231 843962 1219193 754410 0 584207 207918 716646 862902 494411 189478 956546 715703 574175 417119 0 1322857 2230784 1820982 2917198 2389545 2251890 1467873 1806729 1854922 1953734 2345396 1046421 2274068 1310279 1552924 663052 0 2077284 1513647 1624761 1324088 0 2477356 1707359 1833359 1895907 0 1993639 1534524 2721605 1494116 1774475 809433 1702290 2033977 1720725 2060053 702232 552438 743789 422977 601022 658626 660758 782952 604886 819501 211175 728389 378351 741819 621870 530073 256780 0 941254 689612 905434 572634 0 557386 799744 1001652 812362 0 581313 776714 700709 628661 737669 508269 677284 888446 925380 530951 2115833 1892291 1583470 1811461 2670582 2861550 1940168 2689680 2512571 889394 1576638 1445639 1280169 1412741 1648639 1739511 2023991 0 2408672 3177631 1634670 2177184 0 1628474 2284507 2041974 1913574 0 2007499 3016440 2164565 2251831 1209182 2533153 2906367 1671538 2344192 2177030 +AAEAYLNFAEADAR MGYG000003697_02405 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,2FNRM@200643|Bacteroidia,4AKT2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_02405 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 367999 0 473559 0 289169 0 361912 628375 0 0 0 0 0 0 0 0 0 397866 0 0 0 0 332752 0 608443 0 0 448470 0 0 0 0 243281 463035 0 0 335618 307522 1002627 0 127279 0 242473 0 0 1819477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675544 0 1002505 204482 0 0 0 0 0 1352267 550789 0 0 0 1522232 202267 902625 0 0 0 596701 0 967098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436626 553207 0 0 0 0 0 742093 0 0 0 0 0 0 1451519 0 1063751 0 2950777 0 1215188 1500659 0 0 0 0 0 0 0 0 0 8171745 0 0 0 0 14345240 0 1227973 1402688 0 8450781 0 0 0 3212963 650787 1369608 0 0 1504336 1759896 2265753 0 2818626 0 1865402 0 79914 3565555 0 0 0 0 0 0 0 0 0 9142226 0 0 0 0 237417 0 2879814 0 0 195217 0 0 0 172930 2769379 6656582 0 0 0 6989779 +AAEAYLNYIEAC(Carbamidomethyl)YEK MGYG000000243_00118 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0457@1|root,COG0457@2|Bacteria,4NG3F@976|Bacteroidetes,2FM0I@200643|Bacteroidia,4AKP7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00118 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 695855 0 1421237 887613 948471 601561 1096435 812875 919085 0 0 0 731828 0 0 0 678887 453987 726400 0 0 373565 653790 948819 0 692167 0 449863 0 0 1967419 1128751 1916324 907301 0 778427 663122 1583928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3488460 0 0 0 0 0 0 0 0 0 0 421218 312054 197446 0 0 0 0 0 373738 0 0 0 0 270590 232809 0 0 0 0 0 0 0 0 318493 0 0 298741 831815 0 0 0 0 0 328700 0 0 376882 0 574091 256672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 34204 0 0 166699 0 0 0 0 0 0 0 0 0 0 0 0 247752 0 0 28531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30130 0 0 0 0 0 0 0 0 0 0 0 0 +AAEAYR MGYG000002492_00917;MGYG000000262_02232;MGYG000000077_02465;MGYG000000076_01479 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,25UX1@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.75 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.25 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1027163 0 0 0 0 0 0 0 0 0 0 0 997090 0 0 0 0 0 0 0 1012480 0 0 1357755 0 0 0 0 0 826331 0 0 0 0 1291333 0 0 0 1439136 0 0 0 0 0 1258112 0 1309548 0 0 0 0 880069 0 0 0 1626464 1415475 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3308386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1279258 0 0 0 0 0 +AAEC(Carbamidomethyl)AVIVGNAK MGYG000002720_00009 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes 1.0 1239|Firmicutes 1.0 J 1.0 elongation factor G 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_00009 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 597205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517238 0 0 0 0 0 0 0 0 0 0 654502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227064 0 338762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEDAFTSR MGYG000004797_02944 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_02944 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K01802:E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]|K03770:ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 535480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEDFAVGNVVK MGYG000000184_00844;MGYG000001338_01638 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3XZ91@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cytoplasmic, score 9.98 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_00844 0.5 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1|K03527:ispH, lytB; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] 1.0 none 1.0 0 1032571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1499816 0 0 0 0 0 0 0 1815799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1022586 0 0 0 0 0 0 0 1459758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1522672 0 0 0 0 0 0 0 4122914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1299425 0 0 0 0 0 0 0 2260280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2999873 0 0 0 0 0 0 +AAEDFDDSAFGR MGYG000003683_01773 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG3250@1|root,COG3250@2|Bacteria,2GMAT@201174|Actinobacteria,4CYYS@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 3.2.1.23 1.0 ko:K01190 1.0 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 1.0 - 1.0 R01105,R01678,R03355,R04783,R06114 1.0 RC00049,RC00452 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N,Laminin_G_3,RicinB_lectin_2 1.0 3.2.1.23 1.0 GH2 1.0 GH2 1.0 GH2 1.0 MGYG000003683_01773 1.0 beta-galactosidase. lactase. Some enzymes in this group hydrolyze alpha-L-arabinosides; some animal enzymes also hydrolyze beta-D-fucosides and beta-D-glucosides (cf. EC 3.2.1.108). Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D- galactosides. 1.0 1.0 1.0 1.0 Galactose metabolism|Other glycan degradation|Sphingolipid metabolism|Metabolic pathways 1.0 K01190:lacZ; beta-galactosidase [EC:3.2.1.23] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1071539 0 0 0 0 162574 0 0 0 0 857228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEDGAAAAPAQS(Deoxy[S](Ser->Ala)EPK MGYG000002517_01392 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0643@1|root,COG2198@1|root,COG0643@2|Bacteria,COG2198@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 Signal transducing histidine kinase homodimeric 1.0 cheA 1.0 - 1.0 2.7.13.3 1.0 ko:K03407 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW,H-kinase_dim,HATPase_c,Hpt,P2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01392 1.0 histidine kinase. protein kinase (histidine). This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine).-!-A number of histones can act as acceptor. ATP + protein L-histidine = ADP + protein N-phospho-L-histidine. 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03407:cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3] 1.0 none 1.0 0 0 0 437560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417239 0 0 0 0 0 0 0 0 0 0 196602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726434 0 0 941392 0 0 0 0 1022521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 785195 0 0 0 0 0 0 0 0 0 0 1039711 0 586192 0 0 694161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEDLFLGR MGYG000001378_03057 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,2FNEA@200643|Bacteroidia,4AKUK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins 1.0 ftsH 1.0 - 1.0 - 1.0 ko:K03798 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000,ko01002,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,FtsH_ext,Peptidase_M41 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_03057 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03798:ftsH, hflB; cell division protease FtsH [EC:3.4.24.-] 1.0 none 1.0 0 0 0 853066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 821258 1008402 0 0 0 0 0 0 0 0 0 0 0 482006 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287071 0 0 0 0 0 0 0 0 0 0 0 0 437250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271552 274447 0 0 0 0 0 298341 0 0 0 0 0 570105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEDMELK MGYG000000254_03300 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Marinifilaceae|g__Odoribacter|s__Odoribacter splanchnicus|m__MGYG000000254 1.0 COG5010@1|root,COG5010@2|Bacteria,4PMJW@976|Bacteroidetes,2G0E2@200643|Bacteroidia,2326G@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_19,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000254_03300 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 1169181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974794 0 0 0 0 0 0 0 0 0 0 449725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366117 0 0 0 0 0 0 0 0 0 0 506651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 636496 0 0 0 0 0 0 0 0 0 0 145025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545483 0 0 0 0 0 0 0 +AAEDRENQIR MGYG000000164_01314 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3XYH6@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_01314 1.0 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 1207912 0 0 1164923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEDVNKQELK MGYG000000196_00497 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 2F08Y@1|root,33TCA@2|Bacteria,4NTB5@976|Bacteroidetes,2FRQT@200643|Bacteroidia,4AT8I@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Fibronectin type 3 domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BACON,F5_F8_type_C 1.0 - 1.0 - 1.0 - 1.0 CBM0 1.0 MGYG000000196_00497 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1376652 1464428 1283211 1747857 0 0 1853465 1664276 1640436 1449599 824601 0 0 1690181 0 0 1317171 0 0 1371009 0 0 0 0 1671795 1678488 1529904 0 3144037 0 0 2054598 1275272 2305362 1660585 1716008 1823700 1074775 1572559 1743601 1516195 1800131 0 0 2403185 2332318 1337043 2395047 1950911 0 0 2757382 0 0 2052857 0 0 2005090 0 0 0 0 1900710 2177301 2274798 0 2051388 0 0 2435012 1721301 2529005 2141507 1899307 2293047 1937742 789361 1124129 1046766 942025 0 0 1244638 1331478 1600206 592798 869227 0 0 1177409 0 0 717128 0 0 1035415 0 0 0 0 1083414 1111814 987911 0 1470906 0 0 1111383 809612 1269877 1261331 1388073 1068978 898927 76728 674418 585867 673597 0 0 578693 677116 663765 518984 309844 0 0 429908 0 0 432126 0 0 465280 0 0 0 0 584080 695870 453591 0 743927 0 0 658052 656681 997524 740319 916026 1204428 661390 901680 600742 681220 1006328 0 0 993401 1135897 832757 844085 811634 0 0 748001 0 0 740422 0 0 1292870 0 0 0 0 1050611 1268249 689614 0 142443 0 0 477303 561862 1247346 1131778 1004846 1479760 959587 +AAEEAGLDLVK MGYG000003166_00981 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539885|m__MGYG000003166 1.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,3WIZW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins 1.0 infC 1.0 - 1.0 - 1.0 ko:K02520 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 IF3_C,IF3_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_00981 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02520:infC, MTIF3; translation initiation factor IF-3 1.0 none 1.0 0 0 1627952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1088769 0 0 0 0 0 0 0 0 0 0 0 0 1022375 0 0 2574001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2841996 0 0 0 0 0 0 0 2841245 0 0 0 0 2231533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 693849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 980473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423473 +AAEEALAAEQLK MGYG000000262_00560 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0305@1|root,COG0305@2|Bacteria,1W6Y2@1239|Firmicutes,25M5M@186801|Clostridia,25ZAD@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 L 1.0 Participates in initiation and elongation during chromosome replication 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DnaB_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_00560 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1282941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1390085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1103323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 720128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEEAPAAPPAPPAPTKEEVLLTEIR MGYG000000196_00480 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG1970@1|root,COG1970@2|Bacteria,4NQ49@976|Bacteroidetes,2FT2E@200643|Bacteroidia,4AQQ5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell 1.0 mscL 1.0 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 1.0 - 1.0 ko:K03282 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.22.1 1.0 - 1.0 - 1.0 MscL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00480 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03282:mscL; large conductance mechanosensitive channel 1.0 none 1.0 0 0 0 448598 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 567207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEEAPAEEAPAEA MGYG000002293_01607 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01607 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1963902 0 0 0 0 2095798 0 2079117 0 0 1077689 0 0 0 0 0 0 0 2069750 0 0 0 0 0 0 0 935819 2084151 0 0 0 0 2036727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEEDRHEFVR MGYG000000187_00889 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,25V03@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family 1.0 glgD 1.0 - 1.0 2.7.7.27 1.0 ko:K00975 1.0 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 1.0 M00565 1.0 R00948 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Hexapep,NTP_transferase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000187_00889 1.0 glucose-1-phosphate adenylyltransferase. ADP-glucose synthase. - alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate. 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biofilm formation - Escherichia coli 1.0 K00975:glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 870331 0 0 0 0 787864 0 0 0 0 752627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166066 0 0 0 0 100136 0 0 0 0 179157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 235665 0 0 0 0 0 0 0 0 0 0 +AAEEFR MGYG000000142_01470 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3XZ7P@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 - 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000000142_01470 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4583560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEEGDIAAR MGYG000003697_01726;MGYG000002960_00421 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0152@1|root,COG0152@2|Bacteria,4NF1Z@976|Bacteroidetes,2FPKZ@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 F 1.0 Belongs to the SAICAR synthetase family 1.0 purC 1.0 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 6.3.2.6 1.0 ko:K01923 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04591 1.0 RC00064,RC00162 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 SAICAR_synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01726 0.5 phosphoribosylaminoimidazolesuccinocarboxamide synthase. SAICAR synthetase. Forms part of the purine biosynthesis pathway. 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4- carboxamido]succinate + ADP + 2 H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01923:purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5164940 0 0 0 0 0 0 0 0 0 0 0 0 1939614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEEGIADLK MGYG000003819_00854 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__UMGS1872|s__UMGS1872 sp900555795|m__MGYG000003819 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,2N697@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003819_00854 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 1284440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 837782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEEGIEYTK MGYG000000077_00695;MGYG000000262_00844 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,24FUX@186801|Clostridia,25VQY@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 S 1.0 Dihydroxyacetone kinase, L subunit 1.0 dhaL 1.0 - 1.0 2.7.1.121 1.0 ko:K05879 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00695 0.5 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways 1.0 K05879:dhaL; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaL [EC:2.7.1.121] 1.0 none 1.0 548534 1071657 557189 391847 0 1243351 129332 829078 0 864361 0 0 0 0 822513 1052614 0 0 735206 753538 707118 1142617 0 349444 961956 527175 302017 0 423987 0 843804 1019605 556800 749132 301506 0 353843 479837 1262425 1286879 682555 1014251 0 768217 1933904 931278 0 873472 0 0 0 0 658268 449552 0 0 944375 1203916 725283 742766 0 1633788 808143 995816 1026395 0 2384974 0 1019258 838154 714231 1152380 714587 0 1012223 703597 2349613 2984273 675627 2598100 0 1775363 1225972 2445346 0 2114336 0 0 0 0 2709011 1974067 0 0 2679096 2608525 1780965 2712758 0 1264840 2623787 2250707 2731728 0 525859 0 629193 2025322 1393126 3038643 2747724 0 1872265 571765 1552274 1861213 1157204 2002313 0 1668139 2323339 969525 0 1458779 0 0 0 0 1049493 2575324 0 0 1148796 2252631 653370 1352569 0 1348424 1280373 805695 1451483 0 1858023 0 1012143 1158473 1469111 734234 1051945 0 819307 1401856 346289 910328 1087322 887613 0 1146860 905368 533756 0 310123 0 0 0 0 289501 928912 0 0 743725 252204 549351 1397882 0 1277121 445069 325107 283219 0 238690 0 1595182 1135995 1512172 594366 321033 0 237913 859567 +AAEEIAAGR MGYG000002720_00404;MGYG000002794_01705;MGYG000002156_00381 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,4BWU3@830|Butyrivibrio 1.0 186801|Clostridia 1.0 C 1.0 NADH:flavin oxidoreductase / NADH oxidase family 1.0 - 1.0 - 1.0 1.3.1.31 1.0 ko:K10797 1.0 ko00360,ko01120,map00360,map01120 1.0 - 1.0 R02252 1.0 RC00669 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Oxidored_FMN,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_00404 0.3333333333333333 2-enoate reductase. enoate reductase. Acts, in the reverse direction, on a wide range of alkyl and aryl alphabeta-unsaturated carboxylate ions; 2-butenoate was the best substrate tested. butanoate + NAD(+) = (2E)-2-butenoate + H(+) + NADH. 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Microbial metabolism in diverse environments 1.0 K10797:enr; 2-enoate reductase [EC:1.3.1.31] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1602811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1860172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEELFTGHISTGAMNDLER MGYG000000243_02615 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0465@1|root,COG0465@2|Bacteria,4NF0E@976|Bacteroidetes,2FNEA@200643|Bacteroidia,4AKUK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins 1.0 ftsH 1.0 - 1.0 - 1.0 ko:K03798 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000,ko01002,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,FtsH_ext,Peptidase_M41 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02615 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03798:ftsH, hflB; cell division protease FtsH [EC:3.4.24.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579833 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEELIFHSITTGASNDIEQATK MGYG000000142_02465 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XZ55@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins 1.0 ftsH 1.0 - 1.0 - 1.0 ko:K03798 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000,ko01002,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,FtsH_ext,Peptidase_M41 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_02465 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03798:ftsH, hflB; cell division protease FtsH [EC:3.4.24.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 445073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822606 0 0 0 0 0 0 0 +AAEELNKR MGYG000002506_04803;MGYG000002515_02416;MGYG000003365.1_00759;MGYG000002494_00622;MGYG000003372_00502;MGYG000002535_03054 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3634@1|root,COG3634@2|Bacteria,1MUKD@1224|Proteobacteria,1RNC7@1236|Gammaproteobacteria,3XPHP@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Alkyl hydroperoxide reductase 1.0 ahpF 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008785,GO:0009321,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.0 - 1.0 ko:K03387 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 GIDA,Pyr_redox_2,Pyr_redox_3,Thioredoxin_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04803 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03387:ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-] 1.0 none 1.0 0 65766 127036 0 27757 221225 0 134642 0 110758 0 0 0 0 0 0 0 0 0 0 0 214707 0 153339 0 0 0 0 0 0 0 0 51550 114278 0 0 0 80792 0 522002 624015 291886 666309 926316 0 332285 0 343558 0 0 0 0 0 0 0 0 0 0 0 1140473 0 1031441 0 0 0 0 0 0 0 0 337898 310103 0 0 0 322623 0 189679 252721 130880 168228 332428 0 186294 0 220032 0 0 0 0 0 0 0 0 0 0 0 312726 0 321423 0 0 0 0 0 0 0 0 283803 237809 0 0 0 191584 0 265644 182640 241408 208052 236340 0 163267 0 228550 0 0 0 0 0 0 0 0 0 0 0 317773 0 292014 0 0 0 0 0 0 0 0 162594 295496 0 0 0 225856 0 0 0 0 0 0 0 230994 0 36415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144845 0 0 0 0 38889 +AAEELR MGYG000000003_02003;MGYG000002203_00962;MGYG000003022_01479;MGYG000000258_00354;MGYG000003279_02141;MGYG000003022_01477;MGYG000001315_01431 domain d__Bacteria 1.0 COG0019@1|root,COG0019@2|Bacteria,4NFHV@976|Bacteroidetes,2G0KY@200643|Bacteroidia 0.42857142857142855 976|Bacteroidetes 0.42857142857142855 E 0.7142857142857143 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 0.42857142857142855 speA 0.42857142857142855 - 1.0 4.1.1.19 0.42857142857142855 ko:K01585 0.42857142857142855 ko00330,ko01100,map00330,map01100 0.42857142857142855 M00133 0.42857142857142855 R00566 0.42857142857142855 RC00299 0.42857142857142855 ko00000,ko00001,ko00002,ko01000 0.7142857142857143 - 1.0 - 1.0 - 1.0 Orn_Arg_deC_N,Orn_DAP_Arg_deC 0.42857142857142855 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_02003 0.14285714285714285 arginine decarboxylase. L-arginine carboxy-lyase. - H(+) + L-arginine = agmatine + CO2. 0.42857142857142855 0.42857142857142855 0.42857142857142855 0.42857142857142855 Arginine and proline metabolism|Metabolic pathways 0.42857142857142855 K01585:speA; arginine decarboxylase [EC:4.1.1.19] 0.42857142857142855 none 1.0 671341 649417 99066 980321 899132 584673 1773175 0 1130024 1049419 1437412 885962 808842 946486 1051556 1005984 870519 0 1049927 885895 1510282 1083679 0 0 1480594 908669 1129594 0 1112210 962543 1200841 748845 965134 860257 1515944 884694 802341 940658 4521559 3252613 4235428 5210142 4482318 4432813 3818618 11524658 3255768 5051521 6302097 6498023 4619782 5037073 4361750 5168183 5219026 0 7705417 3902029 3517329 4343630 0 4347326 4410054 5292482 5732917 0 4157418 3618715 4934116 4512188 2114854 4081931 8738141 3226684 3945345 3593297 1924143 2425654 2523251 2563436 2757089 2635610 2134698 4872500 2401651 2814539 2324103 2600119 2502999 2608298 3084089 2913360 3037757 0 3209090 3456776 3849223 3383842 0 8368501 3117346 3235944 2399278 0 2912508 1755167 2279596 2560989 2881496 3640871 7561491 3402462 2715887 2586922 775728 926865 1470600 687172 959905 1142518 1622420 796520 0 779421 975644 943268 435562 675664 191390 928575 755997 0 591664 458105 349241 742126 0 1420740 656406 750129 667608 0 873790 734887 1056831 901365 1189846 1411669 1099042 510811 801517 727324 0 873398 652054 247576 170918 883667 276042 734780 1040308 207717 386064 162030 0 371673 636571 145748 311621 0 198693 0 818545 355059 0 1257361 265888 323301 325124 0 412886 273238 601135 0 1980780 335836 798836 308593 311662 345029 +AAEELRDALYAK MGYG000003022_01479;MGYG000003022_01477 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella|s__Parasutterella sp000980495|m__MGYG000003022 1.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2W02M@28216|Betaproteobacteria,4PQCS@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 E 1.0 Fumarase C C-terminus 1.0 aspA 1.0 - 1.0 4.3.1.1 1.0 ko:K01744 1.0 ko00250,ko01100,map00250,map01100 1.0 - 1.0 R00490 1.0 RC00316,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FumaraseC_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003022_01479 0.5 aspartate ammonia-lyase. fumaric aminase. - L-aspartate = fumarate + NH4(+). 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01744:aspA; aspartate ammonia-lyase [EC:4.3.1.1] 1.0 none 1.0 0 195118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 589596 513407 682747 0 1436457 786024 0 1447078 0 1404417 1258528 636459 1200365 751586 0 0 0 0 315968 0 0 1188946 0 447764 0 701572 825343 0 1487315 0 277520 0 1041708 0 1378704 853462 883356 460401 1288303 2601264 1763951 0 2278909 2624024 0 4766212 0 1790086 1906126 1699684 1937473 1478353 0 0 0 0 1577742 0 0 1527810 0 2328252 0 1002557 1025971 0 1786545 0 2163318 0 1059683 0 4751297 1375687 1045017 1716569 0 0 0 0 0 84315 0 240838 0 0 0 175830 0 62337 0 0 0 0 93669 0 0 0 0 0 0 343134 0 0 0 0 0 0 0 0 589960 108215 0 0 0 0 0 0 87359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70521 0 0 0 0 0 0 0 160479 0 +AAEELRDALYAKAK MGYG000003022_01479;MGYG000003022_01477 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella|s__Parasutterella sp000980495|m__MGYG000003022 1.0 COG1027@1|root,COG1027@2|Bacteria,1R9JY@1224|Proteobacteria,2W02M@28216|Betaproteobacteria,4PQCS@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 E 1.0 Fumarase C C-terminus 1.0 aspA 1.0 - 1.0 4.3.1.1 1.0 ko:K01744 1.0 ko00250,ko01100,map00250,map01100 1.0 - 1.0 R00490 1.0 RC00316,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FumaraseC_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003022_01479 0.5 aspartate ammonia-lyase. fumaric aminase. - L-aspartate = fumarate + NH4(+). 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01744:aspA; aspartate ammonia-lyase [EC:4.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 927997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEEQGLEAGSDEYK MGYG000002641_01217;MGYG000001300_01661;MGYG000003899_00099;MGYG000002651_02100 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,3WI31@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 ABC-type branched-chain amino acid transport systems periplasmic component 1.0 livK 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002641_01217 0.25 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 1.0 K01999:livK; branched-chain amino acid transport system substrate-binding protein 1.0 none 1.0 551459 945077 808391 0 0 759861 542026 0 594006 0 622707 426569 1078229 0 0 997921 1120746 0 979807 1124905 0 989806 0 837477 523200 740381 0 0 0 0 905806 0 1164931 828347 0 0 309720 938712 328339 268266 312352 0 240227 336579 388901 0 548226 0 143965 338131 0 0 0 187648 383258 686658 407110 483460 0 147777 745770 382330 312452 368611 0 887615 0 0 491911 0 370564 340425 0 0 261117 410969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213655 0 0 0 0 598610 0 0 0 0 179080 0 0 0 0 0 0 0 0 0 0 942658 1571570 1268582 0 1112248 1398222 2300962 0 1099450 0 917933 1461048 1125926 0 0 1183858 1734293 487038 1059543 1329186 0 1561048 0 1650455 1326144 1219226 0 0 0 0 1428471 0 892693 1539285 0 0 939784 845293 0 0 0 0 0 0 153559 0 363806 0 0 0 0 0 0 0 0 0 746945 413148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEESAEEIQAA(Ala->Ser)LK MGYG000000249_01313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_01313 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 596847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEESAEEIQAALK MGYG000000249_01313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_01313 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1168136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1169990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEESAEEIQS(Methylamine)ALK MGYG000001315_01852 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,27I7U@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01852 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2294316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEESAEEIQSALK MGYG000001315_01852 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,27I7U@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01852 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 678299 1287593 455105 508012 465234 502950 946085 669696 961376 913340 766632 706307 318073 0 674661 0 0 669447 1329141 0 776034 0 446424 411354 594273 550856 0 597237 0 402103 526700 765061 0 685517 600105 545401 1048850 1248025 1527045 1136558 1551671 950836 1036543 1320430 1400321 983102 960113 830358 754155 1276353 1029116 0 613889 0 0 1365017 1456057 0 281166 0 1786443 1393446 1251782 1404650 0 1738824 0 1532997 1489640 1131686 1404139 1205412 1595843 1106367 1336753 488478 0 448825 501451 397742 0 322049 405573 0 0 0 362669 0 448620 0 0 0 0 0 0 0 254767 0 561789 347429 0 307923 0 0 0 0 328236 302933 384893 280365 0 0 400162 792112 970494 1872304 481151 910888 1277868 418065 486648 702179 1035142 1351797 1547494 1219893 487231 0 1388149 0 0 404474 676021 0 1487992 0 1207938 375434 511604 568866 0 633235 0 1022367 710944 2070650 503442 399103 557947 436300 2038807 563264 565924 1069933 576093 0 0 886682 667910 423784 494794 616695 469781 440983 856218 0 295414 0 0 463219 0 0 461143 0 473545 425387 306696 715030 0 647844 0 449916 313691 1493034 584711 670983 539481 412904 1249913 +AAEESAEEISA(Ala->Gln)ALK MGYG000000038_00850 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena|m__MGYG000000038 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,27URK@189330|Dorea 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_00850 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 975133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1555136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEESAEELQAAVK MGYG000002492_02054 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_02054 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 819079 377488 900359 138173 0 506069 493074 527803 782292 402685 0 0 0 512290 0 0 539972 444407 0 0 1327196 217204 454082 0 546536 1360818 0 0 689588 0 552630 0 597718 0 0 783948 0 0 2513352 914597 1192139 817405 0 835053 796251 798648 1255223 1293724 0 0 0 1332151 0 886507 1169829 792015 0 715308 1284429 670697 909787 0 754022 1372800 0 0 1224028 0 2646366 0 851746 0 0 2410371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838858 0 0 0 598286 0 0 0 0 0 0 0 0 500360 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877849 0 0 0 0 0 0 0 0 0 0 0 1422658 0 0 0 0 292982 0 0 0 0 0 0 0 0 0 0 +AAEESAEELSAAVK MGYG000001637_00515;MGYG000003215_00740;MGYG000000271_01162 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_00515 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 501105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309083 0 0 0 0 0 0 0 0 0 0 674408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334052 0 0 0 0 0 0 0 0 0 0 510724 0 +AAEESAEELSAAVK(Propionamide) MGYG000001637_00515;MGYG000003215_00740;MGYG000000271_01162 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_00515 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 1166330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1136498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396740 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEESGFNIR MGYG000004548_00792;MGYG000002517_02832 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 phosphate acetyltransferase 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHFR_1,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004548_00792 0.5 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00625:pta; phosphate acetyltransferase [EC:2.3.1.8] 1.0 none 1.0 254911 653004 0 334803 0 0 0 354521 0 0 0 0 0 0 395369 0 385396 0 464520 313264 0 0 0 0 0 0 373599 0 0 0 0 0 0 180207 232149 260571 232868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2667332 683408 218335 2408121 0 872244 1366379 2799854 2256971 1427687 926165 959092 885809 2939264 2388551 0 1655335 0 1795797 2160008 1031957 378307 0 0 3259114 2500217 2354966 0 0 1833096 932615 0 551603 1288354 2776601 2347093 2754762 725957 1205306 1257463 2045529 0 0 1589194 1582742 1045330 1230257 1953027 1378163 1437760 1173856 1732352 1772342 0 2401926 0 2570036 1346182 1209542 1170585 0 1439361 2179744 1529187 1818799 0 0 1180165 1317683 0 1973099 1570648 1205857 2265126 2406567 1753474 +AAEESIEDIK MGYG000004464_00237;MGYG000001346_02222;MGYG000004748_01432;MGYG000000236_00775 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0206@1|root,COG0206@2|Bacteria,4NF8N@976|Bacteroidetes,2FMJV@200643|Bacteroidia,4AMA1@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004464_00237 0.25 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1720126 0 0 0 0 0 0 0 0 770919 0 0 0 0 0 0 0 0 0 0 1409667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEESIEEVK MGYG000001338_00984;MGYG000000213_00744;MGYG000000212_01066;MGYG000000200_00529;MGYG000004733_02036;MGYG000002966_03727;MGYG000000184_01385;MGYG000000252_02354;MGYG000000133_01126;MGYG000000171_01210;MGYG000002298_01448 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3XYK3@572511|Blautia 0.5454545454545454 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_00984 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 1174182 1592137 1016086 662641 0 2231625 584595 955137 741793 947934 1570547 1343782 1198507 732444 924896 1329523 1120520 4162813 743101 1105643 1566001 2268848 1062591 1058071 1373921 857039 863757 1995813 2216697 1635415 917236 1620594 971263 989637 1190446 808608 770719 1109277 809229 2223307 566944 739934 695922 277023 578401 524445 549294 379305 613118 0 600058 317186 316968 0 122139 902193 658346 588197 725952 0 352202 711173 591346 527775 576615 719455 1132878 1058505 2597961 1039787 623867 1016916 512534 475687 410171 668337 927754 0 894325 566480 0 741077 363990 1124270 0 1283801 0 1022017 847833 601988 1101880 1021787 1215604 0 678030 859922 932008 0 328096 0 870873 999675 1179219 702008 918980 881782 1361515 1938594 1534747 1242132 1027282 0 1202992 1298764 0 2332143 666579 594545 1008736 676686 775139 0 429990 648270 742124 739714 675918 0 312583 699556 733559 0 0 654421 765892 444048 0 586449 172504 249060 0 0 2961610 1199788 1880573 1277510 632293 0 0 0 142192 928801 3430749 4337578 3854567 3869881 1174357 2875301 7654340 3834412 2697423 4331897 4215699 3547343 2682857 5021569 3608717 3367615 2844324 535606 3431316 1202510 4911460 3552456 1078873 3293249 3529217 4081258 4792887 1012680 4354925 896831 3515331 5012335 6093659 4339300 3822988 5684535 2064256 3279269 +AAEESKDEIANALK MGYG000002641_01976;MGYG000002619_00769;MGYG000000195_00044;MGYG000002040_00746;MGYG000002224_00374;MGYG000003899_00809;MGYG000002274_02915;MGYG000003291_00009;MGYG000002272_00283;MGYG000002545_02263;MGYG000000022_00593;MGYG000003937_01659;MGYG000002223_00729;MGYG000002610_00941;MGYG000001255_01690;MGYG000004700_01055;MGYG000000039_01295;MGYG000001300_02629 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 0.9444444444444444 - 1.0 MGYG000002641_01976 0.05555555555555555 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 1132838 1417357 1597531 1814293 891190 1214283 1353451 992890 1418885 0 1252353 1092745 1335876 1220444 961658 1441710 1354311 2314603 1500198 1257686 0 1104568 1941457 1425955 1200634 1263502 1093598 2014495 0 1031554 1279006 1067930 1503233 1952335 0 1279379 1556235 1645433 0 1485273 1753727 2423470 1240967 1723084 2419953 1072454 2827206 0 1084074 1389995 1020568 2826585 2956459 1138878 2334840 1597313 3170474 2059264 0 1159055 1406765 1178532 2627601 2239420 1911122 1171232 0 1521150 1322793 1358869 1690913 2035100 0 2015061 1963418 2113193 602890 187337 658257 642218 573572 580358 720683 345081 654214 0 830173 399175 713758 689452 346887 300880 300400 2829105 651422 0 0 0 2357184 546413 461577 637821 575280 2514112 0 535817 566108 632368 281129 518763 0 669739 715299 451178 1273949 1295050 1570021 1161043 1691538 1451883 1671959 1073164 1418887 0 1560044 1970522 1776311 1380171 1555470 1467020 1293431 1675131 1727927 1304656 0 1229130 1981218 1331876 1500774 1399144 1472271 1380345 0 1704713 1461688 1435894 1779450 2006417 0 1451827 1348484 1737019 0 0 0 0 0 226142 0 0 0 0 161676 0 0 0 0 0 0 1109969 0 0 0 0 1101515 229654 0 148726 0 1101774 0 0 0 0 0 0 0 0 0 0 +AAEESKDEITNALK MGYG000003921_01788 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_01788 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEESMEELSSAVK MGYG000002517_01810 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01810 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 537773 0 0 794982 0 370776 230923 439257 348692 642505 0 551737 0 329164 603075 462281 517594 0 686106 441886 518218 0 0 0 595966 514376 652562 0 0 431692 0 0 0 450842 659376 752076 436942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277236 0 0 0 342118 341984 0 0 0 0 349604 533163 0 0 0 0 0 0 0 0 0 0 0 0 2976235 0 583844 2825447 0 966269 1479561 3797587 2951306 1557207 1412643 1335379 0 3243624 2973565 1177430 2248933 0 2699458 2712648 1774921 0 0 351017 3181185 2435444 2716456 0 0 2743343 0 0 662623 1795418 2735192 2124314 2766634 564572 2009161 0 2197312 0 0 1735570 1864007 1617068 2114182 2375103 1191212 1924839 0 2136013 3251226 1697974 2394273 0 2251010 1499193 2564447 1665931 0 1567419 2360633 1780791 2353247 0 0 1429581 0 0 2068301 2222786 1939032 2021963 2392755 1886646 +AAEESQEEISQALK MGYG000000233_02719;MGYG000000205_01980;MGYG000000255_01244 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,21YAS@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02719 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327991 0 0 0 0 346242 0 0 0 0 0 0 0 715785 0 0 647524 0 0 0 0 509513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816363 0 0 0 0 605279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369699 0 0 624825 0 0 0 0 472892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472647 0 0 0 0 552819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEESSEEISA(Ala->Gln)ALK MGYG000000164_02429 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_02429 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1173172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEESSEEISQALK MGYG000000179_03344;MGYG000001622_01293;MGYG000002946_03659;MGYG000004087_01348;MGYG000001311_00488 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,21YAS@1506553|Lachnoclostridium 0.6 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03344 0.2 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 1009108 0 0 901653 0 243595 754320 0 787281 579163 0 0 0 0 645959 348962 0 0 392022 960549 869573 367401 0 376079 567424 1037053 700868 0 872751 690671 0 0 0 505116 687336 0 1069901 0 453721 0 121043 351597 0 0 461876 219887 299432 481730 0 0 239191 379161 337498 243924 0 0 414544 332540 0 0 0 212422 373666 219710 469765 0 319799 349058 0 0 149666 0 294548 166771 386840 0 854932 0 386757 794561 0 0 694988 370991 859239 534524 0 616047 525883 1061943 861913 564479 537462 0 708204 722455 862363 339764 0 0 302708 764484 1012097 0 921691 832149 542380 0 476643 656685 374802 970570 675047 434099 358818 0 0 308773 0 0 0 0 321833 349039 0 0 0 0 369134 358776 0 0 503411 197979 523243 0 0 0 0 0 349141 0 0 455897 0 0 423729 301505 428573 415945 267264 377345 1659772 0 841859 1191683 0 694904 831914 1028356 1640632 1297234 0 891823 607483 1246780 1442412 644213 1270970 0 1268265 1984270 1174980 1179073 0 1294492 868842 1729132 1277606 0 1769001 1155971 854801 0 803239 1099537 820178 1484646 1605929 892185 +AAEETKEAEPEAK MGYG000003683_01359 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG3937@1|root,COG3937@2|Bacteria,2GS3M@201174|Actinobacteria,4D1FE@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 S 1.0 granule-associated protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Phasin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01359 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 549731 0 0 0 0 470624 0 0 49584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140179 0 0 0 0 193563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEETKEAEPEAKAE MGYG000003683_01359 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG3937@1|root,COG3937@2|Bacteria,2GS3M@201174|Actinobacteria,4D1FE@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 S 1.0 granule-associated protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Phasin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01359 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 1179603 0 1078136 1056792 0 0 0 0 0 0 0 0 0 1603081 0 0 0 0 0 0 0 1837539 0 0 0 0 0 0 0 0 1462788 0 0 0 0 663659 0 0 942245 0 768509 764452 0 0 0 0 0 0 2185153 0 0 1083771 0 0 0 0 0 791293 0 1154036 0 0 0 0 0 0 0 0 1164103 0 0 0 0 678957 0 0 647119 0 249943 380652 0 0 0 0 0 0 660577 0 0 748534 0 0 0 0 0 186890 0 166206 0 0 0 0 0 0 0 0 482084 0 0 0 0 345876 0 0 0 0 0 0 0 0 0 0 0 0 687323 0 0 0 0 0 0 0 0 0 0 766337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEEVGASDLTK MGYG000000223_01552 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,3VQHN@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_01552 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02864:RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10 1.0 none 1.0 0 278698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 202584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1564656 0 0 0 0 0 0 0 0 3882949 0 0 0 0 0 0 0 0 0 486057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1979039 0 0 0 0 0 0 0 0 4268187 0 2331038 0 0 0 0 0 0 0 3486085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635420 0 0 0 0 0 0 0 0 380995 0 6195498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEEYPMNLGFLGK MGYG000002835_01962;MGYG000000200_02255;MGYG000000133_02315 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,24D62@186801|Clostridia,3WGSE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family 1.0 ureC 1.0 - 1.0 3.5.1.5 1.0 ko:K01428 1.0 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 1.0 - 1.0 R00131 1.0 RC02798,RC02806 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_1,Urease_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002835_01962 0.3333333333333333 urease. - - 2 H(+) + H2O + urea = CO2 + 2 NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Purine metabolism|Atrazine degradation|Metabolic pathways|Microbial metabolism in diverse environments|Epithelial cell signaling in Helicobacter pylori infection 1.0 K01428:ureC; urease subunit alpha [EC:3.5.1.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2036807 0 0 0 0 753576 0 0 0 0 1604848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032494 0 0 0 0 1782641 0 0 0 0 1399955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354442 0 0 0 0 0 0 0 0 0 0 +AAEFADVLK MGYG000001302.1_00924 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG1027@1|root,COG1027@2|Bacteria,4P1PR@976|Bacteroidetes,2FNWI@200643|Bacteroidia,22U5D@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Aspartate ammonia-lyase 1.0 aspA 1.0 - 1.0 4.3.1.1 1.0 ko:K01744 1.0 ko00250,ko01100,map00250,map01100 1.0 - 1.0 R00490 1.0 RC00316,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FumaraseC_C,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_00924 1.0 aspartate ammonia-lyase. fumaric aminase. - L-aspartate = fumarate + NH4(+). 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01744:aspA; aspartate ammonia-lyase [EC:4.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400307 0 0 0 0 280027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422404 0 0 0 0 348905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1633896 0 0 0 0 1184300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEFDYAGTQAC(Carbamidomethyl)R MGYG000002517_00535 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Carbamoyl-phosphate synthetase ammonia chain 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00535 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01955:carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] 1.0 none 1.0 0 0 0 0 0 0 0 316618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 557196 0 0 0 0 0 0 613993 0 0 0 0 0 943797 0 0 0 0 0 724236 0 0 0 0 0 746078 0 0 0 761822 0 0 0 0 0 0 517420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEFLEEPIER MGYG000000084_01972;MGYG000000724_01019 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000084_01972 0.5 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 815650 0 0 0 0 571092 0 0 0 0 2421619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 886963 0 0 0 0 584090 0 0 0 0 595585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1075045 0 0 0 0 922939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 790198 0 0 0 0 1038701 0 0 0 0 845383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1372548 0 0 0 0 2029155 0 0 0 0 1785458 0 0 0 0 0 0 0 0 0 0 +AAEGAAAAAATEASAC(Carbamidomethyl)AN(Deamidated)C(Carbamidomethyl)AEK MGYG000000003_00044 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000003_00044 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGAAAAAATEASAC(Carbamidomethyl)ANC(Carbamidomethyl)AEK MGYG000000003_00044 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000003_00044 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 1418046 1438025 0 1407713 1314130 1526458 893170 0 1511493 1741333 716593 2527430 0 1451193 2249784 0 2236875 0 1894042 1797021 1802108 1212332 0 2260617 0 2102972 2146866 0 0 2351259 0 0 0 0 1285875 1819976 1348932 0 563848 382781 0 820456 930135 592283 478577 0 601745 900012 471301 1066781 0 716216 921560 0 451429 0 401084 654914 594864 363353 0 529732 0 690363 565255 0 0 699642 0 0 0 0 358543 321840 802550 0 1362692 666011 0 688606 1021336 437474 636554 0 907588 363481 646327 1040528 0 827960 843140 0 313127 0 710889 1076277 1289465 591803 0 504195 0 1010108 910346 0 0 1323020 0 0 0 0 938142 1181683 896888 0 290632 0 0 375543 662118 175842 0 0 502712 390828 154238 786494 0 388821 637924 0 301945 0 720933 357478 443948 0 0 0 0 383156 323665 0 0 441784 0 0 0 0 0 385847 567228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGAATQSVADQEEIK MGYG000001346_02907 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_02907 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 378413 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGAATQSVADQEEIKK MGYG000001346_02907 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_02907 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 318610 395977 560018 259503 431944 0 0 0 2740045 841787 500039 480421 0 910308 388710 446816 0 0 0 355025 534296 420548 0 0 0 517092 0 0 0 582785 411482 0 0 0 0 354627 0 0 913600 739822 0 670361 436844 0 0 0 845603 2024044 570394 655607 0 956113 561312 310519 0 0 0 716757 280661 538591 0 0 0 394639 0 0 0 1120332 642180 0 0 0 0 587914 0 0 844833 746212 1462125 1030103 995972 0 0 0 4442332 849720 877486 840808 0 959263 811186 2032282 0 0 0 681524 1686629 1137836 0 0 0 1579769 0 0 0 700131 614331 0 0 0 0 1072064 0 0 653621 508728 737358 638850 584112 0 0 0 1217592 1583350 705492 484919 0 865278 433132 235180 0 0 0 409825 409700 273304 0 0 0 309223 0 0 0 645342 572129 0 0 0 0 661190 0 0 722142 781487 1040785 756179 715996 0 0 0 5868283 1141971 1384340 199687 0 1219700 733106 1415807 0 0 0 712501 1195261 633762 0 0 0 1268858 0 0 0 648456 327885 0 0 0 0 654083 +AAEGAATQSVAN(Deamidated)QEEIKK MGYG000001370_00660 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fluxus|m__MGYG000001370 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 MGYG000001370_00660 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGAGHSLYTSTDYM(Oxidation)LDGYDNAEPADPVQHR MGYG000000243_02695 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0614@1|root,COG0614@2|Bacteria,4NEF0@976|Bacteroidetes,2FNDC@200643|Bacteroidia,4AMJ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02695 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 559603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642483 0 0 0 0 551371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290845 +AAEGAGHSLYTSTDYMLDGYDN(Deamidated)AEPADPVQHR MGYG000000243_02695 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0614@1|root,COG0614@2|Bacteria,4NEF0@976|Bacteroidetes,2FNDC@200643|Bacteroidia,4AMJ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02695 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 1108663 0 0 0 0 0 0 0 0 0 0 1671700 0 0 0 0 0 1695819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 931156 0 0 0 474612 0 0 0 0 0 0 0 0 0 0 621037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGAGHSLYTSTDYMLDGYDNAEPADPVQHR MGYG000000243_02695 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0614@1|root,COG0614@2|Bacteria,4NEF0@976|Bacteroidetes,2FNDC@200643|Bacteroidia,4AMJ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02695 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 2668083 3004896 6957129 4438162 2875867 2514392 3885120 3512998 3368466 1561529 2557790 2753027 1313191 2742586 1950907 1313835 2285650 994011 2275482 2004000 2228975 2335955 1823013 3320984 2520942 2814195 3108780 2546984 2513959 3741715 7335511 2967928 5704183 3536910 3133258 3335033 2656715 5702901 932449 776044 1057041 1262393 1670501 1376303 1153127 1705457 864295 1530360 1610734 1086669 1751383 1666214 1504220 2228824 1645715 536304 1413207 1221852 1425259 1499575 701508 1381737 1216638 1563701 1663208 271874 1075599 1328964 973742 1712183 957061 1024239 1356261 1063794 1264583 1118621 888937 486713 871697 706650 1327856 1228380 1375607 558601 1020355 944959 1025640 1099517 897620 1083192 887660 948392 615461 1357522 1170758 620987 768878 201632 803858 1311300 965060 1243943 523275 633102 620539 917201 1233796 805863 989290 252184 1111917 1296696 1543699 1145629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGAIGIAEK MGYG000000251_02115;MGYG000000142_02731;MGYG000001615_01983;MGYG000000233_02118;MGYG000001338_01296;MGYG000002528_00119;MGYG000000205_02543;MGYG000001707_00757;MGYG000000262_01832;MGYG000003425_04615;MGYG000002517_01686;MGYG000004733_02764;MGYG000002492_01963;MGYG000000212_00326 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.21428571428571427 186801|Clostridia 0.8571428571428571 S 0.8571428571428571 Psort location Cytoplasmic, score 8.87 0.35714285714285715 - 0.8571428571428571 - 1.0 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 1.0 - 1.0 - 1.0 GGGtGRT 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_02115 0.07142857142857142 - - - - 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 978382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3943931 0 0 0 0 0 0 4601626 0 0 0 0 0 0 0 5004474 0 0 4876314 0 0 0 2888106 0 0 0 6069781 4713004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGAIGIAR MGYG000000036_01924;MGYG000003937_01695 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000036_01924 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5397697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGDDALMEK MGYG000004158_01417 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister invisus|m__MGYG000004158 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4H2Y7@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000004158_01417 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 369465 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGEDEQKAVEHLVK MGYG000002494_03969 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1925@1|root,COG1925@2|Bacteria,1N0CV@1224|Proteobacteria,1S9R2@1236|Gammaproteobacteria,3X2IH@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 PTS HPr component phosphorylation site 1.0 ptsH 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005981,GO:0006109,GO:0006793,GO:0006796,GO:0006810,GO:0008047,GO:0008150,GO:0008152,GO:0008643,GO:0008965,GO:0008982,GO:0009401,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015144,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0019197,GO:0019222,GO:0022804,GO:0022857,GO:0030234,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032881,GO:0032991,GO:0034219,GO:0043085,GO:0043467,GO:0043470,GO:0043471,GO:0044093,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045819,GO:0045913,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051179,GO:0051234,GO:0055085,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0065009,GO:0070873,GO:0070875,GO:0071702,GO:0080090,GO:0098772 1.0 - 1.0 ko:K02784 1.0 ko02060,map02060 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02000 1.0 8.A.8.1.1 1.0 - 1.0 e_coli_core.b2415,iAF1260.b2415,iB21_1397.B21_02276,iBWG_1329.BWG_2177,iE2348C_1286.E2348C_2601,iEC042_1314.EC042_2624,iEC55989_1330.EC55989_2705,iECABU_c1320.ECABU_c27360,iECBD_1354.ECBD_1266,iECB_1328.ECB_02315,iECDH10B_1368.ECDH10B_2580,iECDH1ME8569_1439.ECDH1ME8569_2349,iECDH1ME8569_1439.EcDH1_1246,iECD_1391.ECD_02315,iECED1_1282.ECED1_2859,iECH74115_1262.ECH74115_3646,iECIAI1_1343.ECIAI1_2473,iECIAI39_1322.ECIAI39_2561,iECNA114_1301.ECNA114_2492,iECO103_1326.ECO103_2934,iECO111_1330.ECO111_3145,iECO26_1355.ECO26_3468,iECOK1_1307.ECOK1_2732,iECP_1309.ECP_2439,iECS88_1305.ECS88_2605,iECSE_1348.ECSE_2706,iECSF_1327.ECSF_2279,iECSP_1301.ECSP_3363,iECUMN_1333.ECUMN_2737,iECW_1372.ECW_m2644,iECs_1301.ECs3287,iEKO11_1354.EKO11_1313,iETEC_1333.ETEC_2528,iEcDH1_1363.EcDH1_1246,iEcE24377_1341.EcE24377A_2702,iEcHS_1320.EcHS_A2550,iEcSMS35_1347.EcSMS35_2570,iEcolC_1368.EcolC_1263,iG2583_1286.G2583_2947,iJO1366.b2415,iJR904.b2415,iLF82_1304.LF82_1769,iNRG857_1313.NRG857_12110,iPC815.YPO2993,iSBO_1134.SBO_2439,iSDY_1059.SDY_2612,iSFV_1184.SFV_2467,iSF_1195.SF2470,iSFxv_1172.SFxv_2719,iSSON_1240.SSON_2504,iS_1188.S2616,iSbBS512_1146.SbBS512_E2765,iUMN146_1321.UM146_04545,iUMNK88_1353.UMNK88_3017,iUTI89_1310.UTI89_C2749,iWFL_1372.ECW_m2644,iY75_1357.Y75_RS12655,iZ_1308.Z3681,ic_1306.c2950 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03969 1.0 - - - - 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 K02784:ptsH; phosphocarrier protein HPr 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 68347 0 0 367406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1871337 1667442 0 1704266 3048703 0 0 0 1596552 0 0 0 0 0 0 0 0 1260948 0 0 3569903 0 2751078 0 0 0 0 0 0 0 1834065 1577616 0 0 0 0 2192008 0 451028 0 0 0 819493 0 0 0 0 0 0 0 0 0 0 0 0 377188 0 0 654531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGGDILFVGTK MGYG000000022_01263;MGYG000001300_00246;MGYG000002223_00595;MGYG000000039_00227;MGYG000002274_00630;MGYG000002651_00048 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01263 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 995446 1034726 995268 0 500832 737528 1045934 0 1380483 1035922 1296304 987892 941523 0 0 826858 999354 0 1045895 1050597 0 884209 0 1271810 946383 1332717 1361845 0 0 1093855 0 0 912902 1329492 0 0 1038659 976981 989566 715108 1053428 0 899577 801489 1236451 0 895419 0 776094 918023 1408950 0 0 670303 1283033 0 1132026 867987 0 634568 0 623080 1058262 1003621 732579 0 0 1019420 0 0 781410 1044583 0 0 682618 815957 597902 412530 627009 0 688319 584091 606049 0 633571 619998 652211 747534 621273 0 0 481006 686608 0 595789 480829 0 533252 0 746207 569340 679390 319452 0 0 637310 0 0 469752 537927 0 0 608834 576170 651140 694896 965727 0 1375668 1049889 873290 0 1267409 713059 2027150 1261778 1228164 0 0 1606801 1469753 0 1235247 834726 0 1190292 0 1127843 752639 783924 757318 0 0 847648 0 0 783659 976602 0 0 672991 537047 382987 257889 677831 0 192185 431165 304527 0 320602 0 357801 383089 193363 0 0 507724 0 0 502895 289117 0 734127 0 367436 285395 258099 460339 0 0 239450 0 0 588198 467283 0 0 422824 553579 +AAEGGDILFVGTKK MGYG000002272_01435;MGYG000001300_00246;MGYG000000039_00227;MGYG000002274_00630;MGYG000002545_00160 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 - 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002272_01435 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 757547 702584 999845 1153984 0 741149 455733 0 700478 0 0 0 0 0 0 0 0 452780 1053091 0 0 695234 697386 855508 0 816878 0 801093 0 0 0 0 787637 999492 0 0 307120 1013171 556919 311314 922304 686367 0 631348 876130 0 926148 0 0 0 0 0 0 0 0 274913 736210 0 0 362375 149277 323860 0 340975 0 438804 0 0 0 0 553470 410653 0 0 474738 615698 286259 325037 163993 268327 0 531609 233498 0 324010 0 0 0 0 0 0 0 0 343971 403615 0 0 235110 256266 522172 0 311417 0 324597 0 0 0 0 238770 316257 0 0 169652 290083 582881 563016 1136800 521504 0 879824 726508 0 659883 0 0 0 0 0 0 0 0 271979 991352 0 0 775542 597723 933729 0 808594 0 286697 0 0 0 0 1238126 1205126 0 0 728198 244086 245993 218436 490545 167178 0 447235 124961 0 484382 0 0 0 0 0 0 0 0 204212 417868 0 0 497870 380348 502000 0 506850 0 618924 0 0 0 0 326363 480806 0 0 549442 171442 +AAEGGFDISGAQIVDPEKSDR MGYG000000142_02451 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,3XZ2B@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_02451 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00625:pta; phosphate acetyltransferase [EC:2.3.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1008902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGGFDISGATIVDPETSDR MGYG000000133_02974 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,3XZ2B@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02974 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00625:pta; phosphate acetyltransferase [EC:2.3.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 765449 0 0 0 0 0 0 0 0 0 0 579354 0 0 0 745121 0 0 0 0 530391 0 0 0 0 +AAEGIAPK MGYG000002506_04253 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1049@1|root,COG1049@2|Bacteria,1MVCR@1224|Proteobacteria,1RNMC@1236|Gammaproteobacteria,3XP43@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Involved in the catabolism of short chain fatty acids (SCFA) via the tricarboxylic acid (TCA)(acetyl degradation route) and the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the reversible isomerization of citrate to isocitrate via cis-aconitate. Also catalyzes the hydration of 2-methyl-cis- aconitate to yield (2R,3S)-2-methylisocitrate. The apo form of AcnB functions as a RNA-binding regulatory protein. During oxidative stress inactive AcnB apo-enzyme without iron sulfur clusters binds the acnB mRNA 3' UTRs (untranslated regions), stabilizes acnB mRNA and increases AcnB synthesis, thus mediating a post-transcriptional positive autoregulatory switch. AcnB also decreases the stability of the sodA transcript 1.0 acnB 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006417,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019222,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032787,GO:0034248,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046395,GO:0046459,GO:0046487,GO:0047456,GO:0048037,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071704,GO:0072329,GO:0072350,GO:0080090,GO:0097159,GO:1901363,GO:1901575,GO:2000112 1.0 4.2.1.3,4.2.1.99 1.0 ko:K01682 1.0 ko00020,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 1.0 M00009,M00010,M00012,M00173 1.0 R01324,R01325,R01900,R04425 1.0 RC00497,RC00498,RC00618,RC01153 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECIAI1_1343.ECIAI1_0116,iPC815.YPO3415 1.0 Aconitase,Aconitase_2_N,Aconitase_B_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04253 1.0 aconitate hydratase. | 2-methylisocitrate dehydratase. citrate hydro-lyase. | (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase. Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate.-!-The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate.-!-cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate.-!-Formerly EC 4.2.1.4. | The enzyme from the fungus Yarrowia lipolytica does not act on isocitrate. citrate = D-threo-isocitrate. | (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = 2-methyl-cis-aconitate + H2O. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K01682:acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3910203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGILTVR MGYG000001423_03022;MGYG000001367_01857;MGYG000004735_00207;MGYG000004087_01282;MGYG000004642_01131 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,36DMF@31979|Clostridiaceae 0.4 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001423_03022 0.2 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1994659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGLC(Menadione-HQ)KTLVSEDGKK MGYG000001338_02308 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02308 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1011900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877650 0 0 0 0 527274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395550 0 0 0 0 381408 +AAEGLHMRPAGVIAR MGYG000002492_00320 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,25XE8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 PTS HPr component phosphorylation site 1.0 ptsH 1.0 - 1.0 - 1.0 ko:K11189 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00320 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K11189:- 1.0 none 1.0 0 0 83074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 387179 412709 889817 0 0 0 0 0 2525087 0 2164686 0 0 0 0 1650530 0 0 0 0 1134618 0 0 0 0 1135624 0 0 0 0 283891 0 0 0 0 572884 0 0 615952 0 319185 0 0 0 0 0 525612 0 258301 0 0 0 0 801764 0 0 0 0 1086564 0 0 0 0 1268890 0 0 0 0 726311 0 0 0 0 914828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGSVHSDNFR MGYG000002492_00394 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00394 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 0 0 324591 0 335208 0 0 0 0 0 391264 0 449842 0 0 276793 0 433509 0 0 0 0 219790 0 0 0 0 295420 0 0 0 0 310340 0 0 0 0 175736 0 0 1082493 0 1453665 0 0 0 0 0 1266976 0 1372711 0 0 1201098 0 4461658 0 0 0 0 1967120 0 0 0 0 3154505 0 0 0 0 940094 0 0 0 0 1240733 0 0 6056962 0 1883231 0 0 0 0 0 2187377 0 3032477 0 0 3034452 0 1215090 0 0 0 0 1823503 0 0 0 0 2267672 0 0 0 0 5583749 0 0 0 0 6956769 0 0 641055 0 290756 0 0 0 0 0 872581 0 84554 0 0 390502 0 1173152 0 0 0 0 588394 0 0 0 0 1021209 0 0 0 0 570127 0 0 0 0 726862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGSVHSDNFRR MGYG000002492_00394 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00394 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177452 0 0 0 0 0 0 0 1592942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994382 0 0 0 0 1415312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGTEFAALDPHLEGPTALAVSKDDATAPAR MGYG000000242_00770 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,269HE@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000242_00770 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02864:RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489346 0 0 0 0 760056 0 0 0 0 1044601 0 0 0 0 0 0 0 0 0 0 +AAEGTEFAALEPQLEGPTALAVSKEDATAPAR MGYG000000179_05049;MGYG000000198_05827 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,269HE@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors 1.0 rplJ 1.0 - 1.0 - 1.0 ko:K02864 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_05049 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02864:RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10 1.0 none 1.0 685695 0 0 278879 0 0 0 0 279502 0 0 0 0 493804 0 0 0 0 0 0 0 216481 0 0 482633 531932 328410 0 376801 0 0 0 0 0 0 382899 265166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 214636 0 0 0 0 0 0 0 0 0 0 0 0 337452 0 248694 0 0 0 0 0 0 0 178182 0 459779 0 200243 288187 0 0 0 0 488092 0 0 0 0 540410 0 0 0 0 0 0 0 282103 0 0 0 0 323797 0 623389 0 0 0 243657 0 0 206778 0 252306 0 0 0 223627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 849679 0 628478 986673 0 320524 0 0 820955 0 0 0 0 1619846 0 0 0 0 0 0 0 424331 0 638052 839662 1133950 1208263 0 1261913 0 0 0 969200 0 0 1251935 883104 498677 +AAEGTGIEIAPLK MGYG000002485_02279;MGYG000002574_00479 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG4656@1|root,COG4656@2|Bacteria,3791P@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4,Fer4_10,Fer4_17,Fer4_4,Fer4_7,Fer4_9,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_02279 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03615:rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 737531 479876 1575850 0 702557 2563509 0 0 0 2072889 1605092 0 1511699 0 0 2102634 1168045 0 1063490 0 0 2363038 0 1963625 0 814730 844599 0 0 752275 1649835 762000 1645807 0 0 0 683520 1436534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354383 0 229594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEGWAR MGYG000002494_02221 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,3XNJZ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Glycyl-tRNA synthetase beta subunit 1.0 glyS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.14 1.0 ko:K01879 1.0 ko00970,map00970 1.0 M00360 1.0 R03654 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 1.0 DALR_1,tRNA_synt_2f 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02221 1.0 glycine--tRNA ligase. glycyl-tRNA synthetase. - ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01879:glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] 1.0 none 1.0 0 0 97997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228410 0 0 0 0 97363 0 0 931967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 952921 0 0 0 0 805168 0 0 379633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156552 0 0 0 0 295267 0 0 376361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347437 0 0 0 0 124627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91300 0 0 0 0 0 +AAEHLAHTGLLK MGYG000002994_01435 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Megasphaeraceae|g__Megasphaera|s__Megasphaera sp002319965|m__MGYG000002994 1.0 COG4670@1|root,COG4670@2|Bacteria,1TP5H@1239|Firmicutes,4H37Q@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 Belongs to the 3-oxoacid CoA-transferase family 1.0 - 1.0 - 1.0 2.8.3.1 1.0 ko:K01026 1.0 ko00620,ko00640,ko00643,ko01100,ko01120,map00620,map00640,map00643,map01100,map01120 1.0 - 1.0 R00928,R01449,R05508 1.0 RC00012,RC00014,RC00137 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002994_01435 1.0 propionate CoA-transferase. - Butanoate and lactate can also act as acceptors. acetyl-CoA + propanoate = acetate + propanoyl-CoA. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Styrene degradation|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K01026:pct; propionate CoA-transferase [EC:2.8.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1522061 0 0 0 0 0 0 0 0 0 0 0 +AAEHPSEQVGK MGYG000000245_00071;MGYG000000325_00446;MGYG000000271_00298;MGYG000004271_02052 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 1.0 186801|Clostridia 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000245_00071 0.25 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 1206303 860887 659242 1919503 992508 1034432 1665662 725414 1608194 1493497 2571629 2284661 1183858 924544 2140640 1152058 1505034 2006059 996168 1168687 1482561 1259313 2167886 1128811 2011847 1375731 1564148 2493211 1120810 1996788 640514 870934 547434 1327624 696163 1375940 1155217 568096 87292 32572 0 52324 56819 0 0 0 0 0 71781 66163 0 55794 0 0 0 506492 0 0 169672 38337 855349 0 0 0 63702 852922 29023 39681 52038 59774 0 0 45642 0 74215 0 514278 358034 0 536935 185308 200242 402087 531822 676336 272933 397465 1004454 745293 731990 725923 661541 637215 199293 629673 675951 526366 161390 97374 202841 732316 884996 846297 217486 460406 730994 143729 143427 205877 445632 277995 697830 947496 143509 96994 0 59021 80534 100968 42406 67511 57055 0 54652 135511 414048 0 75663 0 86575 0 140170 0 139340 0 0 0 0 67958 93237 65879 192982 0 97842 0 138413 0 0 75497 0 0 128506 354431 172328 275469 0 49091 274255 493502 185144 458339 401608 226056 1058326 342304 358569 480943 216503 495458 1547355 393362 303416 79913 364396 3023852 314535 355055 538195 317533 828104 119026 403807 78468 125246 241690 337799 281146 780550 427849 229548 +AAEHPSEQVGKEIR MGYG000000245_00071;MGYG000000271_00298;MGYG000004271_02052 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 1.0 186801|Clostridia 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000245_00071 0.3333333333333333 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEHPSEVVGEEIR MGYG000004735_00452;MGYG000001315_02512 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,4BW62@830|Butyrivibrio 0.5 186801|Clostridia 1.0 EH 0.5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 0.5 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00452 0.5 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 520643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254756 0 0 0 0 272011 0 0 238043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 301608 0 0 0 0 332128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101553 0 0 0 0 0 0 0 218094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183413 0 0 0 0 363637 0 0 298801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194182 0 0 0 0 393632 +AAEHPSEVVGEEIRK MGYG000001315_02512 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,36DKA@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS10005,iHN637.CLJU_RS10010 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_02512 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEHVVGVAK MGYG000000201_02350;MGYG000000223_00229;MGYG000001315_00988;MGYG000002528_00902 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia 0.25 186801|Clostridia 1.0 C 1.0 Rubrerythrin 0.75 rbr3A 1.0 - 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_02350 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 182397 199198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053794 0 0 0 0 626681 0 0 0 0 988803 0 0 124284 0 338546 0 0 0 0 434283 0 0 73952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 57120 0 0 0 0 61017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49732 0 0 0 0 0 0 0 0 0 0 0 0 71191 0 0 0 0 0 0 0 0 1149894 509014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733103 0 0 0 0 268657 0 0 0 0 2090998 0 0 1117184 0 651564 0 0 0 0 1014505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEI(Xle->Val)PEAIRK MGYG000000136_02061;MGYG000002670_00403;MGYG000001315_01353;MGYG000002234_01458;MGYG000004733_00985;MGYG000003891_01006;MGYG000000252_01802;MGYG000000280_01284;MGYG000000031_02249;MGYG000000142_02050;MGYG000002492_00392;MGYG000000135_01188;MGYG000000690_01576;MGYG000000028_01605;MGYG000004689_01598;MGYG000002517_02856;MGYG000000002_00865;MGYG000002966_02558;MGYG000001186_01095;MGYG000000213_00197;MGYG000004296_00406;MGYG000000806_01299;MGYG000002278_02309;MGYG000000050_01189;MGYG000002298_00345;MGYG000000193_02113;MGYG000000201_02098;MGYG000000301_00177;MGYG000004879_01580;MGYG000001338_02790;MGYG000002528_01856;MGYG000000164_02747;MGYG000001689_02303;MGYG000000562_01931;MGYG000000133_00062;MGYG000001645_00457;MGYG000000212_03064;MGYG000000184_01189;MGYG000003694_02445;MGYG000000216_02346;MGYG000000251_01814;MGYG000001637_00014;MGYG000000187_01741 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.46511627906976744 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000136_02061 0.023255813953488372 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1653331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEIAKNTM(Oxidation)AER MGYG000000271_00931 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins 1.0 iscS 1.0 - 1.0 2.8.1.7 1.0 ko:K04487 1.0 ko00730,ko01100,ko04122,map00730,map01100,map04122 1.0 - 1.0 R07460,R11528,R11529 1.0 RC01789,RC02313 1.0 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00931 1.0 cysteine desulfurase. cysteine desulfurylase. The sulfur from free L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors.-!-The enzyme is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin).-!-In Azotobacter vinelandii, this sulfur provides the inorganic sulfide required for nitrogenous metallocluster formation. [sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine. 1.0 1.0 1.0 1.0 Thiamine metabolism|Metabolic pathways|Sulfur relay system 1.0 K04487:iscS, NFS1; cysteine desulfurase [EC:2.8.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEIAKNTMAER MGYG000000271_00931 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins 1.0 iscS 1.0 - 1.0 2.8.1.7 1.0 ko:K04487 1.0 ko00730,ko01100,ko04122,map00730,map01100,map04122 1.0 - 1.0 R07460,R11528,R11529 1.0 RC01789,RC02313 1.0 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00931 1.0 cysteine desulfurase. cysteine desulfurylase. The sulfur from free L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors.-!-The enzyme is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin).-!-In Azotobacter vinelandii, this sulfur provides the inorganic sulfide required for nitrogenous metallocluster formation. [sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine. 1.0 1.0 1.0 1.0 Thiamine metabolism|Metabolic pathways|Sulfur relay system 1.0 K04487:iscS, NFS1; cysteine desulfurase [EC:2.8.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEIATANMK MGYG000002517_00912 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins 1.0 iscS 1.0 - 1.0 2.8.1.7 1.0 ko:K04487 1.0 ko00730,ko01100,ko04122,map00730,map01100,map04122 1.0 - 1.0 R07460,R11528,R11529 1.0 RC01789,RC02313 1.0 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00912 1.0 cysteine desulfurase. cysteine desulfurylase. The sulfur from free L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors.-!-The enzyme is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin).-!-In Azotobacter vinelandii, this sulfur provides the inorganic sulfide required for nitrogenous metallocluster formation. [sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine. 1.0 1.0 1.0 1.0 Thiamine metabolism|Metabolic pathways|Sulfur relay system 1.0 K04487:iscS, NFS1; cysteine desulfurase [EC:2.8.1.7] 1.0 none 1.0 809019 0 426703 635154 0 554316 0 0 0 0 0 0 0 507993 0 509466 525863 0 0 0 657792 604797 0 534759 0 594910 0 0 0 0 0 0 718892 0 0 0 480073 372896 217325 0 348500 0 0 0 0 0 0 0 0 0 0 0 0 320353 0 0 0 0 0 152473 0 0 0 314092 0 0 0 0 0 0 0 0 0 0 270911 0 0 0 305143 0 0 307147 0 0 0 0 0 0 0 0 0 267754 175325 0 0 0 0 543009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2721052 0 0 2776166 0 3674433 0 0 0 0 0 0 0 2705961 0 3275283 2611056 0 0 0 2730066 2449569 0 731092 0 2652198 0 0 0 0 0 0 1937493 0 0 0 3130239 3818825 1076995 0 2917502 0 0 2834310 0 0 0 0 0 0 0 2247979 0 1576125 2156247 0 0 0 1994071 2146956 0 2180304 0 1663370 0 0 0 0 0 0 2396133 0 0 0 1623382 2245944 +AAEIDEEERFPMETVEK MGYG000002926_00639;MGYG000002720_01506 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,2N683@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 I 1.0 Psort location Cytoplasmic, score 9.97 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_00639 0.5 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 585369 0 0 0 0 0 0 0 0 1099917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 819873 0 0 0 0 0 0 0 0 0 0 643309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352991 0 0 0 0 0 0 0 0 382508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179340 0 0 0 0 0 0 0 0 0 0 458886 0 408610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 592245 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEIGKELEAELNQK MGYG000001313_00488 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,2FMB9@200643|Bacteroidia,4AM6Q@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Oxidoreductase, short chain dehydrogenase reductase family protein 1.0 uxuB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_00488 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1128497 0 0 0 0 1043655 0 0 0 0 777982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 97819 0 0 0 0 0 0 0 0 0 0 +AAEIIDAFNEQGGAF(Oxidation[F](Phe->Tyr)K MGYG000000243_01974 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01974 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443011 0 0 0 0 0 0 0 0 0 0 0 0 961141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4158155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1594134 0 0 0 0 669900 0 0 0 0 564362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEIIDAFNEQGGAFK MGYG000000243_01974 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01974 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724408 0 1107859 0 0 0 0 0 0 0 0 0 0 0 0 717206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 919583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEIIDAFNEQGGAYK MGYG000002478_00802 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00802 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1084914 0 0 0 0 937345 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2210699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEIIR MGYG000002033_00724;MGYG000002438_02893;MGYG000000243_00603;MGYG000004464_00649 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,22W81@171551|Porphyromonadaceae 0.75 976|Bacteroidetes 1.0 C 1.0 Electron transfer flavoprotein 0.75 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002033_00724 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2399333 0 0 0 +AAEIIREGLYR MGYG000004797_03900;MGYG000001787_00188;MGYG000000243_00603 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,4AN6T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG2086 Electron transfer flavoprotein beta subunit 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_03900 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEILDAFNEQGGAYK MGYG000002478_00802;MGYG000003367_01247 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00802 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEILDAYNEQGGAFK MGYG000003693_00190;MGYG000001306_02657;MGYG000001364_02757 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_00190 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3590379 0 0 0 0 4395911 0 0 0 0 3761221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEILDAYNEQGGAFKR MGYG000003693_00190;MGYG000001306_02657 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_00190 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2258169 0 0 0 0 2834471 0 0 0 0 2347681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239989 0 0 0 0 0 0 0 0 0 271066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316437 0 0 0 0 912660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEILDK MGYG000000650_00860;MGYG000000909_00761;MGYG000000198_01719;MGYG000001619_01872 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,21YT8@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) 1.0 purE 1.0 - 1.0 5.4.99.18 1.0 ko:K01588 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R07405 1.0 RC01947 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000650_00860 0.25 5-(carboxyamino)imidazole ribonucleotide mutase. N(5)-carboxyaminoimidazole ribonucleotide mutase. In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates.-!-In the absence of EC 6.3.2.6, the reaction is reversible.-!-The substrate is readily converted into 5-amino-1-(5-phospho-D- ribosyl)imidazole by non-enzymic decarboxylation. 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1- (5-phospho-D-ribosyl)imidazole-4-carboxylate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01588:purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] 1.0 none 1.0 632340 0 0 0 0 0 0 0 0 0 0 0 0 518389 653925 0 0 0 0 0 0 0 0 0 0 508327 0 0 0 0 0 0 0 0 0 0 793627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 497095 304415 0 0 0 0 0 0 0 0 0 0 292015 0 0 0 0 0 0 0 0 0 0 322058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1969015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1427739 0 0 0 0 0 0 0 0 0 0 0 0 1003437 577671 0 0 0 0 0 0 0 0 0 0 1273794 0 0 0 0 0 0 0 0 0 0 816116 0 +AAEILDLTEYLDRKPK MGYG000003683_01833;MGYG000002395_01772;MGYG000001292_02614;MGYG000002469_02049 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CYU6@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 E 1.0 Belongs to the ABC transporter superfamily 1.0 ugpC 1.0 - 1.0 - 1.0 ko:K10112 1.0 ko02010,map02010 1.0 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1 1.0 - 1.0 - 1.0 ABC_tran,TOBE,TOBE_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01833 0.25 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10112:msmX, msmK, malK, sugC, ggtA, msiK; multiple sugar transport system ATP-binding protein [EC:7.5.2.-] 1.0 none 1.0 53276 242817 668010 0 495850 388954 87375 628810 0 305761 767861 2973644 859581 0 156273 398926 321284 0 214967 361537 342347 286060 0 81372 376249 282341 217504 0 601784 517608 230609 400986 353001 294481 324674 238543 268371 461918 317387 697919 429156 0 818307 630261 575426 439115 0 642235 1422296 367293 2109954 0 686521 409989 303945 0 400645 447644 372483 532285 0 995062 566412 539902 503842 0 934633 581638 888195 717074 302882 630380 602084 528740 436458 541071 631043 707351 378887 0 364071 219184 267594 703701 0 691198 474629 769236 484184 0 656521 672802 573612 0 443520 654054 450004 601447 0 256126 534770 147666 615742 0 368853 649754 179806 806512 864875 799030 975343 306336 502133 465948 351424 83690 315674 0 478246 552270 384496 131865 0 346302 747335 283842 54078 0 152383 267086 198646 0 64644 135630 226779 827011 0 707285 305739 157690 194068 0 425069 58804 367899 276766 150666 28441 386576 62984 240508 163749 0 0 59502 0 0 0 68757 65027 0 0 0 69486 0 0 0 0 86165 0 160696 79572 92369 0 0 0 0 0 191820 0 259678 466525 31596 0 0 0 0 67313 73285 0 +AAEILNTVNK MGYG000000196_00042 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG3538@1|root,COG3538@2|Bacteria,4NGY6@976|Bacteroidetes,2FM8H@200643|Bacteroidia,4AMK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Conserved protein 1.0 - 1.0 - 1.0 - 1.0 ko:K09704 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_125 1.0 3.2.1.- 1.0 GH125 1.0 GH125 1.0 GH125 1.0 MGYG000000196_00042 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K09704:K09704; uncharacterized protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEILR MGYG000002438_02893;MGYG000004797_03900;MGYG000000179_00118;MGYG000004105_01672;MGYG000000243_00603;MGYG000000354_00400;MGYG000004711_01572;MGYG000002033_00724;MGYG000000273_00875;MGYG000002445_02556;MGYG000000262_01672;MGYG000000650_01893;MGYG000001531_01601;MGYG000000278_01741;MGYG000004479_00382;MGYG000003504_00715;MGYG000001608_02430;MGYG000001787_00188;MGYG000000233_00376;MGYG000001364_02529;MGYG000004464_00649;MGYG000002218_00405;MGYG000000133_02950;MGYG000001300_00650;MGYG000004468_01621;MGYG000001954_00593;MGYG000001750_01698;MGYG000000170_02403;MGYG000001789_02010;MGYG000004735_00212;MGYG000001783_00812;MGYG000001367_01866;MGYG000004087_01272;MGYG000000043_03473;MGYG000000174_04854;MGYG000001429_00437;MGYG000001619_00903;MGYG000001655_00932;MGYG000000355_01943;MGYG000001489_04896;MGYG000002025_02339;MGYG000000301_01699 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,22W81@171551|Porphyromonadaceae 0.2619047619047619 976|Bacteroidetes 0.5952380952380952 C 0.5952380952380952 Electron transfer flavoprotein 0.3333333333333333 etfB 0.5952380952380952 - 1.0 - 0.9285714285714286 ko:K03521 0.5952380952380952 - 0.9285714285714286 - 0.9523809523809523 - 0.9285714285714286 - 0.9285714285714286 ko00000 0.5952380952380952 - 1.0 - 1.0 - 1.0 ETF 0.5952380952380952 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02893 0.023809523809523808 - - - - 0.9285714285714286 0.9285714285714286 0.9285714285714286 0.9285714285714286 - 0.9285714285714286 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.5952380952380952 none 1.0 2112445 0 0 0 3745738 2568348 0 0 0 0 1808449 2267130 0 0 2001751 3308487 1930921 2078688 0 234794 2667716 0 2144836 0 0 2311620 0 1979675 2017012 2541422 0 2418575 3846040 2321996 0 0 0 0 2250342 0 2657913 1515842 2460690 2280111 0 2070977 0 0 0 2363656 2525996 0 2622143 2501285 2206744 1817817 1857525 1393942 2316514 0 2850782 2316636 2334479 2196160 2067793 2670786 1569945 2383915 1205502 0 2304341 1781166 0 1597077 1226038 2709629 1880779 0 1352030 1811882 0 2873743 0 1689466 0 1955501 1457366 1712186 2614631 0 2302323 2023847 1708788 3344805 0 1832191 1902038 0 2427175 2915148 2167972 1483048 2271902 599847 2386618 0 2199189 2130062 1822801 1729970 0 972342 1555580 2251913 802087 0 827233 1337602 1170030 845273 0 1026160 0 1542279 579726 970327 1270935 0 1250664 515061 804116 701964 741958 895018 1463150 843840 545778 779474 478898 432151 739011 0 821534 1112634 808564 500014 803166 721931 0 956947 706792 686371 1354873 0 1476394 1342255 2962613 1849940 0 1822705 0 1282353 958808 2069779 2768891 0 1254338 2369665 1406407 2741934 1593623 1859209 1240458 1720485 3875974 1480216 1867705 0 981848 2035914 0 2489638 1435161 2346399 910647 1383617 0 1909029 1787874 1708720 +AAEIMDAANNTGNAVK MGYG000000195_00451;MGYG000002040_01210;MGYG000002610_00229;MGYG000002274_00061;MGYG000003899_01644;MGYG000002619_00485;MGYG000003166_01348;MGYG000001255_01101;MGYG000002641_00067 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,3WGPA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 - 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000195_00451 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1655930 0 0 0 0 1561677 0 0 0 0 1537864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4115409 0 0 0 0 4812144 0 0 0 0 4149538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1153969 0 0 0 0 907931 0 0 0 0 892446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1330206 0 0 0 0 2149738 0 0 0 0 1032992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2167557 0 0 0 0 2199816 0 0 0 0 1896790 0 0 0 0 0 0 0 0 0 0 +AAEIMDAFNEQGGAYK MGYG000002549_02928;MGYG000000196_03986 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_02928 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 805358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384343 0 0 0 0 0 0 0 0 0 782736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284495 0 0 0 0 0 0 0 0 0 0 417051 0 0 0 0 0 0 0 0 0 0 0 355478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 551044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 853342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEIMDAFNNQGGAFK MGYG000002293_00508 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00508 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1570239 0 0 0 0 2382420 0 0 0 0 931745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEIMDAYNNQGGAFK MGYG000003697_01471;MGYG000002834_00437 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,22WEA@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01471 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 656220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1193749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3164629 0 0 0 0 5171634 0 0 0 0 2402885 0 0 0 0 523684 0 0 0 0 1024416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEIPEAIR MGYG000000136_02061;MGYG000002670_00403;MGYG000001315_01353;MGYG000002234_01458;MGYG000004733_00985;MGYG000003891_01006;MGYG000000252_01802;MGYG000000280_01284;MGYG000000031_02249;MGYG000000142_02050;MGYG000004630_00952;MGYG000002492_00392;MGYG000000135_01188;MGYG000000690_01576;MGYG000000028_01605;MGYG000004689_01598;MGYG000002517_02856;MGYG000000002_00865;MGYG000002966_02558;MGYG000001186_01095;MGYG000000213_00197;MGYG000004296_00406;MGYG000000806_01299;MGYG000002278_02309;MGYG000000050_01189;MGYG000002298_00345;MGYG000000193_02113;MGYG000000201_02098;MGYG000000301_00177;MGYG000004879_01580;MGYG000001338_02790;MGYG000002528_01856;MGYG000000164_02747;MGYG000001689_02303;MGYG000000562_01931;MGYG000000133_00062;MGYG000000212_03064;MGYG000000184_01189;MGYG000003694_02445;MGYG000000216_02346;MGYG000000251_01814;MGYG000001637_00014;MGYG000000187_01741 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.46511627906976744 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000136_02061 0.023255813953488372 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 8878471 12981380 11420731 5779481 14960059 13671930 5589446 10509670 7667701 9399786 16602501 10537293 12000748 7250767 11519457 11593081 11659981 13847685 8546997 10386418 10290732 0 12093455 6834263 9762334 7568036 8225575 11267266 0 9266593 7552332 12654357 9093341 8206258 9517302 7102038 7319076 10337782 5404902 17320396 7617030 4398345 7439747 3955187 5006259 5306080 4347654 3680675 6597491 4101590 6627473 3164007 3157720 3762309 0 16656149 3557753 4736490 4042436 2517669 8496236 5861277 4184585 3850812 4564469 13986298 6395676 4674716 21051769 8473774 8744186 6168395 5835446 6411643 4919426 9930961 8521959 23311824 23315387 7978577 9249262 11905362 7882042 11106769 7428451 9209578 12253703 8688789 14454735 8831685 10338720 16589011 13472416 9551108 9939372 9014590 10257867 19316882 12787649 9285449 10636708 8473908 11469937 15582878 10875229 10054464 13670158 20592710 26628171 11650601 10323265 6476039 8811076 19787099 14227363 22072533 9196567 14510948 13643532 7279161 8486700 15326771 12676869 9190185 10149481 9448231 10966574 13901812 14187248 10479504 12104031 9145381 9858316 12258051 8859992 6203372 7184795 6344899 12423857 10907330 12180721 8207599 14327685 12281702 17907112 15265371 11015027 7790451 12268604 11112976 11961339 11249327 16422104 26337965 23669279 16286493 8647461 18759696 23292034 16333399 14917161 26071151 19114264 18665720 12113849 23148707 19229829 15981242 19236577 4355142 17062690 7520687 20750687 17917167 7930845 13658053 17260183 12889422 19309438 7912301 19736981 6658684 22600507 22675540 31062557 20121818 12019187 16649539 14441533 21241226 +AAEIPEAIRK MGYG000000136_02061;MGYG000002670_00403;MGYG000001315_01353;MGYG000002234_01458;MGYG000004733_00985;MGYG000003891_01006;MGYG000000252_01802;MGYG000000280_01284;MGYG000000031_02249;MGYG000000142_02050;MGYG000002492_00392;MGYG000000135_01188;MGYG000000690_01576;MGYG000000028_01605;MGYG000004689_01598;MGYG000002517_02856;MGYG000000002_00865;MGYG000002966_02558;MGYG000001186_01095;MGYG000000213_00197;MGYG000004296_00406;MGYG000000806_01299;MGYG000002278_02309;MGYG000000050_01189;MGYG000002298_00345;MGYG000000193_02113;MGYG000000201_02098;MGYG000000301_00177;MGYG000004879_01580;MGYG000001338_02790;MGYG000002528_01856;MGYG000000164_02747;MGYG000001689_02303;MGYG000000562_01931;MGYG000000133_00062;MGYG000001645_00457;MGYG000000212_03064;MGYG000000184_01189;MGYG000003694_02445;MGYG000000216_02346;MGYG000000251_01814;MGYG000001637_00014;MGYG000000187_01741 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia 0.46511627906976744 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000136_02061 0.023255813953488372 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 3702213 5678226 4646806 2659606 7059487 6056282 2259057 4642502 2966131 4490628 6432247 4850365 6096603 3549302 4842878 5033592 3710415 6093738 3876459 4440778 5046326 6432013 5097445 3497848 4360810 3472066 3452837 5366186 3778896 4215637 3618319 5955867 4281218 3649734 4147815 2632721 3704250 5177592 2354350 7217031 3423463 1839257 3432922 1895577 2079407 2150090 2001277 546589 3126170 1759523 3239616 1445550 1488596 779090 1363199 7117020 1646671 2224083 1775666 1379481 3659021 2691415 1711310 1867158 1932019 5370487 3115925 2442528 6737855 3286139 3778785 2572743 2795660 2489210 1845429 4177752 4025978 11206609 11663771 3150217 4986116 5708353 3986591 4840011 3470865 5189319 7052145 5095024 7360676 4618248 4462176 8561197 6468088 4809039 4592623 0 4590252 9490014 6307976 4527585 4857012 3879652 4925081 7331232 5284576 4663494 6574362 9606832 11140113 5499773 4760554 3158716 3750153 9264458 5895884 9854979 4269414 0 6223623 3526012 3483652 6361371 5456331 4486971 5466668 4866377 4492109 6148288 6644962 5706148 5604504 4543017 4818415 5559496 3737704 3238909 0 3574630 4909635 3862357 5587720 4426680 6385224 5995948 9012368 7150159 4619177 3620619 5636714 4717131 6274902 6169574 7236603 12281599 9896214 5692565 4051468 6625383 11090747 6635628 5453472 10122156 8030106 7009427 4328948 9761497 7801394 6615388 7528968 1718831 6424634 2912201 7458218 8367493 2732752 7170470 7798380 7524132 8265693 3139768 8457717 2290888 8097727 9540844 12825831 6364267 7992797 9613383 5300425 6427505 +AAEISADRVEDATTR MGYG000001410_02390 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__Sutterella wadsworthensis_A|m__MGYG000001410 1.0 COG0539@1|root,COG0539@2|Bacteria,1MVAV@1224|Proteobacteria,2VI12@28216|Betaproteobacteria,4PQ3M@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 J 1.0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence 1.0 rpsA 1.0 - 1.0 - 1.0 ko:K02945 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001410_02390 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1 1.0 none 1.0 0 0 0 178647 0 0 74636 0 242494 0 0 0 0 0 0 193171 0 0 0 0 0 0 0 213611 0 0 262120 0 0 0 0 0 0 111672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134223 311104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825172 0 0 1167332 0 1409138 1623165 3009607 1642403 1510966 0 1089583 1911763 0 0 1520870 1276019 0 0 1785816 0 1070299 0 1241927 1450413 1062162 1084310 0 0 1566808 1219400 0 0 1351763 3084280 0 1405090 0 +AAEIYAK MGYG000004296_01529 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Ruminococcus_A|s__Ruminococcus_A faecicola|m__MGYG000004296 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia,3XZJC@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 lacE 1.0 - 1.0 - 1.0 ko:K10188 1.0 ko02010,map02010 1.0 M00199 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.4 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004296_01529 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10188:lacE, araN; lactose/L-arabinose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEK(Lys->Asn)VADLEGDEK MGYG000002528_02459 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,2681F@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002528_02459 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1024272 0 0 0 490521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282771 0 874357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386233 0 0 0 298734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEKFDETR MGYG000002171_02670;MGYG000001787_01249;MGYG000000222_01625;MGYG000002438_00039;MGYG000000322_00356;MGYG000002063_01184;MGYG000004561_00681;MGYG000000044_01844;MGYG000003420_01205;MGYG000001659_01120;MGYG000002922_00071;MGYG000001337_03259;MGYG000000254_00710;MGYG000001360_01047;MGYG000000696_02205;MGYG000001346_01394;MGYG000002218_02323;MGYG000002549_02291;MGYG000000074_01051;MGYG000004797_01692;MGYG000003554_00934;MGYG000002171_01186;MGYG000000236_03660;MGYG000000042_02369;MGYG000001835_01092;MGYG000000196_04898;MGYG000001489_00005;MGYG000003701_00971;MGYG000002033_03235;MGYG000001313_02866;MGYG000003539_01037;MGYG000001783_01115;MGYG000000462_01102;MGYG000000013_04828;MGYG000000215_02858;MGYG000004241_00017;MGYG000004464_00935;MGYG000001661_00506;MGYG000001562_02738;MGYG000002418_01386;MGYG000001780_02752;MGYG000003367_02616;MGYG000002560_03858;MGYG000002455_04389;MGYG000002082_00706;MGYG000002478_03132;MGYG000003282_00840;MGYG000003680_00901;MGYG000003521_01343;MGYG000001789_00637;MGYG000002007_00482;MGYG000004756_00358;MGYG000000003_01643;MGYG000003681_00470;MGYG000002205_01396;MGYG000000243_01020;MGYG000000355_02188;MGYG000001415_00255;MGYG000001750_00580;MGYG000004468_00075;MGYG000003546_00779;MGYG000001302.1_02379;MGYG000002281_02762;MGYG000001655_03175;MGYG000004479_02808;MGYG000003374_01763;MGYG000000781_01995;MGYG000003279_01639;MGYG000003812_01164;MGYG000000224_02424;MGYG000002540_01223;MGYG000000105_02674;MGYG000001599_02329;MGYG000004019_00958;MGYG000003362_02531;MGYG000003423_01692;MGYG000003908_00479;MGYG000003469_01456;MGYG000003812_01753;MGYG000000414_00102;MGYG000000415_01387;MGYG000000053_01058;MGYG000000098_03934;MGYG000001503_01579 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0568@1|root,COG0568@2|Bacteria,4NEBF@976|Bacteroidetes,2FNVQ@200643|Bacteroidia,4AM8U@815|Bacteroidaceae 0.6071428571428571 976|Bacteroidetes 1.0 K 1.0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released 1.0 rpoD 0.9761904761904762 - 1.0 - 1.0 ko:K03086 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03021 1.0 - 1.0 - 1.0 - 1.0 Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_02670 0.011904761904761904 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03086:rpoD; RNA polymerase primary sigma factor 1.0 none 1.0 682018 0 919347 888018 714415 555105 0 654456 932095 0 830364 817921 962192 0 0 1107615 0 706022 0 0 0 653914 854987 1101284 0 877119 738730 629147 746858 0 1094915 0 1122497 0 737047 0 582663 587712 773726 0 593479 712214 991777 730141 0 904564 610480 0 1037792 975536 632806 0 0 1034093 0 373418 0 0 0 858188 814747 570498 0 866967 883604 552632 772621 0 761990 0 721369 0 641241 0 736591 845783 443422 0 584173 617161 934914 793639 0 599053 822125 0 821099 592446 608164 0 0 684087 0 1159777 0 0 0 317682 996162 924738 0 854959 495325 991029 622929 0 930422 0 432706 0 387607 0 426971 611816 590843 0 863282 487482 515599 506013 0 502443 416957 0 852211 597851 448609 0 0 570614 0 831705 0 0 0 452746 71845 480949 0 546903 152870 699259 396966 0 455671 0 528571 0 472623 0 477036 552575 848450 0 489721 764849 1086849 886813 0 743319 641821 0 1109016 885178 1307670 0 0 688455 0 688247 0 0 0 783364 601690 846896 0 1186759 610459 633053 878946 0 631817 0 212128 0 1755886 0 1185272 799443 +AAEKIDVDETGKITGLF MGYG000000133_00802 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3XYQR@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 8.87 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00802 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01938:fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1747403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEKIEALGGK MGYG000001310_00106;MGYG000000164_02745;MGYG000003425_03574;MGYG000000249_01532 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WIV7@541000|Ruminococcaceae 0.75 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_00106 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144015 0 0 0 0 0 0 0 1004805 0 0 0 0 0 0 0 0 0 0 0 0 0 1585744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1017764 0 0 0 0 1128232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188131 0 0 0 0 179887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 824492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99014 0 0 601870 0 0 0 0 0 0 0 0 0 0 0 0 0 404936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258256 +AAEKIEALGGKAEVI MGYG000001310_00106;MGYG000000164_02745;MGYG000000249_01532 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3WIV7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_00106 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 0 0 0 0 903811 1437248 0 0 0 0 0 0 0 0 1163816 866013 697902 0 0 0 0 1667590 0 720033 1076363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775879 421228 0 0 0 0 0 0 0 0 254031 320337 1696340 0 0 0 0 235018 0 379961 399574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182410 164205 0 0 0 0 0 0 0 0 102538 338562 150055 0 0 0 0 225857 0 133577 198116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80772 789181 0 0 0 0 0 0 0 212970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356367 328962 0 0 0 0 0 0 0 0 262739 310218 0 0 0 0 0 150657 0 364227 125570 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEKLEKEHPGK MGYG000000255_02109 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0683@1|root,COG0683@2|Bacteria,1UHWZ@1239|Firmicutes,25E5X@186801|Clostridia,21ZYF@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Protein of unknown function (DUF3798) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF3798 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_02109 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 175154 0 0 115242 0 226668 0 159642 0 0 0 0 223447 0 0 0 227912 0 0 200113 0 174718 0 0 0 0 0 0 0 0 151388 280255 0 0 0 111704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 39601 0 0 79008 0 203846 0 188373 0 0 0 0 138368 0 0 0 266976 0 0 140672 0 63438 0 0 0 0 0 0 0 0 119715 328088 0 0 0 0 0 0 270401 0 0 425040 0 466863 0 622457 0 0 0 0 292093 0 0 0 306738 0 0 377825 0 273619 0 0 0 0 0 0 0 0 219902 375928 0 0 0 208676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEKPVETKPAETK MGYG000000031_02551 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066205|m__MGYG000000031 1.0 2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24UU3@186801|Clostridia,3Y0P6@572511|Blautia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_02551 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEKYNDAR MGYG000001302.1_01986 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_01986 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAELAFEFLPR MGYG000000262_00363 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,25US3@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 - 1.0 - 1.0 - 1.0 ko:K13921 1.0 ko00640,map00640 1.0 - 1.0 R02377 1.0 RC00087 1.0 ko00000,ko00001 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_00363 1.0 - - - - 1.0 1.0 1.0 1.0 Propanoate metabolism 1.0 K13921:pduQ; 1-propanol dehydrogenase 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3787805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14230834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5771148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAELAGNDTIPVEIAR MGYG000002477_00729;MGYG000002494_01504 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3071@1|root,COG3071@2|Bacteria,1MU7A@1224|Proteobacteria,1RMRG@1236|Gammaproteobacteria,3XN16@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Involved in a late step of protoheme IX synthesis 1.0 hemY 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.0 - 1.0 ko:K02498 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 HemY_N,TPR_16,TPR_19,TPR_2,TPR_4,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002477_00729 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02498:hemY; HemY protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309971 0 0 0 0 0 0 0 686047 0 0 1350067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1343650 0 1156723 0 0 0 0 0 0 0 0 708012 0 0 0 0 535364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAELATIEFLK MGYG000002494_02695 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1949@1|root,COG1949@2|Bacteria,1R9WX@1224|Proteobacteria,1S217@1236|Gammaproteobacteria,3XMZQ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 A 1.0 3'-to-5' exoribonuclease specific for small oligoribonucleotides 1.0 orn 1.0 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 1.0 - 1.0 ko:K13288 1.0 ko03008,map03008 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03009,ko03019 1.0 - 1.0 - 1.0 - 1.0 RNase_T 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02695 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome biogenesis in eukaryotes 1.0 K13288:orn, REX2, REXO2; oligoribonuclease [EC:3.1.-.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216759 0 169211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2574026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3210970 0 2128366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 508800 0 581103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAELEDEDAIVER MGYG000002050_01431 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900756725|m__MGYG000002050 1.0 COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CUYV@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Methionine synthase vitamin-B12 independent 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Meth_synt_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002050_01431 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAELENEDV(Val->Ala)IVER MGYG000004875_00848 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp002232035|m__MGYG000004875 1.0 COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CUYV@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Methionine synthase vitamin-B12 independent 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Meth_synt_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004875_00848 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAELFAK MGYG000003694_01610;MGYG000003694_01735 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter faecis|m__MGYG000003694 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 0.5 186801|Clostridia 1.0 C 0.5 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 0.5 nifJ 0.5 - 1.0 1.2.7.1 0.5 ko:K03737 0.5 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 0.5 M00173,M00307 0.5 R01196,R10866 0.5 RC00004,RC02742 0.5 br01601,ko00000,ko00001,ko00002,ko01000 0.5 - 1.0 - 1.0 - 0.5 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 0.5 - 1.0 - 1.0 - 1.0 GT2 0.5 MGYG000003694_01610 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 0.5 0.5 0.5 0.5 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 0.5 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 0.5 none 1.0 0 0 287136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255085 0 0 0 0 0 0 0 0 0 853021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 171082 0 0 328625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2541080 0 0 0 0 0 0 0 0 0 2847200 0 0 0 0 665754 0 0 0 0 1017941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464295 0 0 0 0 375939 0 0 0 0 366531 0 0 0 0 0 0 0 0 0 0 +AAELFAR MGYG000000179_03842;MGYG000003922_00362;MGYG000001065_02072;MGYG000000198_01190;MGYG000001606_00512;MGYG000004087_02250 domain d__Bacteria 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,21YPK@1506553|Lachnoclostridium 0.6666666666666666 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 0.6666666666666666 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000179_03842 0.16666666666666666 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 3682456 2005620 1920300 321940 0 0 2324107 0 2856159 0 2134538 2773109 2860868 3659271 3722175 3300982 3011036 0 0 0 4107932 0 0 0 0 910893 3028404 0 3817330 0 1850763 2557376 2206871 2549055 0 3082452 3503750 2165486 2693107 2519795 2606915 1695105 0 0 1905148 1689692 2731345 2963167 1757779 1511367 2464902 2465222 1716558 2051146 2671766 0 2525313 0 2218534 0 0 0 0 1904748 2028163 0 2874469 0 1807029 1800800 2631882 2458958 0 2229308 2031759 3080666 6554241 3411832 3627013 6716645 0 0 3814128 3350434 4355155 4727193 3373220 2507386 3863858 6167377 6272265 5008355 4675248 0 6538794 0 5695053 0 0 0 0 4541890 6587511 0 6465613 0 2696862 2379987 3651768 4645792 0 4600124 4262882 3137963 2584797 2675948 0 2679224 0 0 2754398 3019108 2585514 3577130 3547078 2737340 4423055 2680097 2736327 4128676 3136537 0 0 0 2029798 0 0 0 0 2384138 2535332 0 2848698 0 418162 2655105 5142189 3452851 0 2752923 2395600 4169735 8575802 3318117 5356230 8850006 0 0 9202200 5848521 8410667 9747241 3117196 6245179 2441513 10612906 8824335 3535160 7210025 0 5705203 0 7006187 0 0 0 0 5861241 8779643 0 11607952 0 4667215 2363352 6540537 7736703 0 6926809 6601459 5245034 +AAELGGK MGYG000001675_00492;MGYG000001338_02192 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,36EGU@31979|Clostridiaceae 0.5 186801|Clostridia 1.0 E 0.5 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdh 0.5 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 0.5 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001675_00492 0.5 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 572062 0 154998 0 0 0 0 0 0 0 0 101326 0 0 866826 0 0 0 0 0 0 290321 0 170842 0 0 0 0 0 0 0 744879 280472 0 0 0 924554 0 650691 0 0 0 0 0 0 0 0 0 0 0 0 0 701403 0 0 0 0 0 0 0 0 0 0 221811 0 0 0 0 0 0 261072 0 0 0 0 842595 0 0 715966 0 0 312667 0 0 0 0 0 412110 0 0 0 0 0 0 0 0 0 310818 0 691823 0 621369 0 0 0 0 0 291759 485140 0 0 0 428927 365908 868799 0 986037 0 0 108360 0 0 0 0 0 564443 0 0 279971 0 0 0 0 0 0 537850 0 566716 0 0 0 0 0 0 0 782606 76504 0 0 0 777090 672759 737503 0 115846 0 0 198558 0 0 0 0 0 0 0 0 895615 0 0 0 0 0 0 731835 0 291397 0 980448 0 0 0 0 0 413438 955314 0 0 0 976685 539227 +AAELGYR MGYG000002517_03141 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Phosphotransferase System 1.0 fruA 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 GGDEF,PTS_EIIA_2,PTS_EIIC,PTS_IIB,Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_03141 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Phosphotransferase system (PTS) 1.0 K02768:fruB; fructose PTS system EIIA component [EC:2.7.1.202]|K02769:fruAb; fructose PTS system EIIB component [EC:2.7.1.202]|K02770:fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] 1.0 none 1.0 152249 0 0 0 0 0 0 0 179626 0 322778 0 0 0 265375 0 0 0 278282 0 0 0 0 0 0 662639 258395 0 0 0 0 0 0 0 0 430545 335433 0 582439 0 0 0 0 0 0 0 0 0 274274 0 0 0 245786 0 0 0 0 0 0 0 0 0 0 263152 392721 0 0 0 0 0 0 0 0 0 500701 0 275263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248729 0 1019067 0 0 0 0 0 0 0 1217781 0 450633 0 0 0 1363061 0 0 0 960666 0 0 0 0 0 0 1076523 1102913 0 0 0 0 0 0 0 0 910552 1110635 0 963236 0 0 0 0 0 0 0 965570 0 1467538 0 0 0 1190375 0 0 0 1041133 0 0 0 0 0 0 1265957 886639 0 0 0 0 0 0 0 0 1525392 1194711 0 +AAELIDMR MGYG000000074_00268 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG3404@1|root,COG3643@1|root,COG3404@2|Bacteria,COG3643@2|Bacteria,4NFE3@976|Bacteroidetes,2FMWT@200643|Bacteroidia,22U9H@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Formiminotransferase domain, N-terminal subdomain 1.0 ftcD 1.0 - 1.0 2.1.2.5,4.3.1.4 1.0 ko:K00603,ko:K13990 1.0 ko00340,ko00670,ko01100,map00340,map00670,map01100 1.0 - 1.0 R02287,R02302,R03189 1.0 RC00165,RC00221,RC00223,RC00688,RC00870 1.0 ko00000,ko00001,ko01000,ko03036,ko04147 1.0 - 1.0 - 1.0 - 1.0 FTCD,FTCD_C,FTCD_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00268 1.0 glutamate formimidoyltransferase. | formimidoyltetrahydrofolate cyclodeaminase. glutamate formyltransferase. | formiminotetrahydrofolate cyclodeaminase. The enzymes also catalyzes formyl transfer from 5-formyltetrahydrofolate to L-glutamate.-!-In eukaryotes, it occurs as a bifunctional enzyme that also has formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) activity.-!-Formerly EC 2.1.2.6. | In eukaroytes, occurs as a bifunctional enzyme that also has EC 2.1.2.5 activity. 5-formimidoyltetrahydrofolate + L-glutamate = (6S)-5,6,7,8- tetrahydrofolate + N-formimidoyl-L-glutamate. | 5-formimidoyltetrahydrofolate + 2 H(+) = (6R)-5,10- methenyltetrahydrofolate + NH4(+). 1.0 1.0 1.0 1.0 Histidine metabolism|One carbon pool by folate|Metabolic pathways 1.0 K00603:fctD; glutamate formiminotransferase / 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]|K13990:FTCD; glutamate formiminotransferase / formiminotetrahydrofolate cyclodeaminase [EC:2.1.2.5 4.3.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 594296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746954 0 0 0 0 0 0 0 0 +AAELIR MGYG000002033_00724;MGYG000001300_00650;MGYG000002438_02893;MGYG000004019_01436;MGYG000004797_03900;MGYG000001489_04896;MGYG000000243_00603;MGYG000004464_00649;MGYG000001789_02010 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,22W81@171551|Porphyromonadaceae 0.4444444444444444 976|Bacteroidetes 0.8888888888888888 C 0.8888888888888888 Electron transfer flavoprotein 0.4444444444444444 etfB 0.8888888888888888 - 1.0 - 0.8888888888888888 ko:K03521 0.8888888888888888 - 0.8888888888888888 - 0.8888888888888888 - 0.8888888888888888 - 0.8888888888888888 ko00000 0.8888888888888888 - 1.0 - 1.0 - 1.0 ETF 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002033_00724 0.1111111111111111 - - - - 0.8888888888888888 0.8888888888888888 0.8888888888888888 0.8888888888888888 - 0.8888888888888888 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.8888888888888888 none 1.0 0 0 3597507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2609688 0 0 0 0 2266343 0 0 0 3964851 0 0 0 2779889 0 2255104 0 0 0 617242 0 0 0 0 0 0 0 2127646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1996689 0 0 0 0 0 0 0 0 0 0 0 0 1990201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1840453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2357610 0 0 0 0 0 0 0 0 0 0 0 0 +AAELLAEGK MGYG000001311_03460;MGYG000000255_02050;MGYG000000179_04958 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,2682U@186813|unclassified Clostridiales 0.6666666666666666 186801|Clostridia 1.0 G 0.6666666666666666 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001311_03460 0.3333333333333333 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 1669875 0 917882 0 0 0 351219 0 1560531 1466617 0 0 0 1912184 0 0 1172919 0 1788451 1803544 2149378 0 0 0 0 1815685 265148 0 475587 1426536 0 0 1282311 627140 0 1530075 1000725 561883 1076119 0 853859 0 0 0 724572 0 1197600 801769 0 0 0 999350 818841 0 641751 0 863660 931373 774770 0 0 0 0 827214 777311 0 1765659 787644 0 0 717240 720615 0 797094 951534 386263 2641489 0 1904029 0 0 0 1957269 0 2592450 2016617 0 0 0 2798611 2201305 0 2283516 0 2270627 2470255 2257137 0 0 0 0 1761492 2219018 0 2933768 2402019 0 0 1801922 1835521 0 2498450 1957076 1851244 1620104 0 1695011 0 0 0 1352327 0 1562212 1895359 0 0 0 1576368 1264413 0 1704713 0 1400402 1666567 1274651 0 0 0 0 1148810 1370047 0 1605984 683766 0 0 1473637 0 0 1272230 1294366 1662167 2798005 0 2013182 0 0 0 2541905 0 2395289 2907349 0 0 0 3463051 2984428 0 2661327 0 2511908 2206641 2390767 0 0 0 0 2971450 2563330 0 3120348 1479779 0 0 2083420 2334425 0 3995558 2025616 1951610 +AAELLDYVR MGYG000002438_02041 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG3637@1|root,COG3637@2|Bacteria,4NE4Y@976|Bacteroidetes,2G0HK@200643|Bacteroidia,2324C@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02041 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 462783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1598202 0 0 0 0 0 0 0 0 1428396 0 0 0 0 0 0 0 0 989791 0 777357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670142 0 0 0 0 0 0 0 0 1021114 0 0 0 0 0 0 0 0 347879 0 854169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAELLR MGYG000002438_02893;MGYG000001300_00650;MGYG000004797_03900;MGYG000000042_01534;MGYG000000423_01318;MGYG000000243_00603;MGYG000000354_00400;MGYG000003701_04105;MGYG000000170_02403;MGYG000001789_02010;MGYG000001783_00812;MGYG000002033_00724;MGYG000000262_01672;MGYG000001655_00932;MGYG000003504_00715;MGYG000001787_00188;MGYG000004464_00649;MGYG000000301_01699;MGYG000000133_02950 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia,22W81@171551|Porphyromonadaceae 0.3157894736842105 976|Bacteroidetes 0.6842105263157895 C 0.6842105263157895 Electron transfer flavoprotein 0.3684210526315789 etfB 0.6842105263157895 - 1.0 - 0.8421052631578947 ko:K03521 0.6842105263157895 - 0.8421052631578947 - 0.8947368421052632 - 0.8421052631578947 - 0.8421052631578947 ko00000 0.6842105263157895 - 1.0 - 1.0 - 1.0 ETF 0.6842105263157895 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02893 0.05263157894736842 - - - - 0.8421052631578947 0.8421052631578947 0.8421052631578947 0.8421052631578947 - 0.8421052631578947 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.6842105263157895 none 1.0 0 0 0 2122860 0 0 2411669 1625579 2175771 1532209 0 0 3324819 2609894 0 0 0 0 2011877 1630611 0 0 0 2935984 2172621 0 0 0 0 0 0 0 0 0 0 2363208 0 4272886 0 0 372961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1038072 0 0 0 0 0 2085259 0 0 1964959 0 0 0 0 0 0 0 1477213 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604786 0 0 237196 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1454422 0 0 0 0 0 954455 0 0 0 0 0 1143224 0 0 0 0 665932 0 0 0 0 0 0 0 0 0 903267 492605 0 0 682878 0 0 0 0 557091 +AAELNQVPYYSR MGYG000002478_00646 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 2DBBS@1|root,2Z89P@2|Bacteria,4NG8V@976|Bacteroidetes,2FPGU@200643|Bacteroidia,4ANVA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like,SusD-like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00646 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 240080 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 967167 1633324 1225709 888796 0 0 1363922 0 933595 0 888388 0 0 1367528 0 639283 1198578 0 0 757780 979054 735606 0 0 746204 920197 1146486 1201534 0 0 1290761 0 0 1183982 0 758015 0 0 604528 567409 1153893 886478 0 0 448065 0 563088 0 901968 0 0 804366 0 1183479 713579 0 0 621045 989288 1070412 0 0 770283 1071221 719256 713158 0 0 519206 0 0 1121463 0 699950 0 0 1453883 444871 1242282 743085 0 0 434342 0 563543 0 643705 0 0 836374 0 1596069 0 0 0 1431435 2142726 1042759 0 0 277281 0 795416 229148 0 0 889251 0 0 532419 0 1114294 0 0 389042 413169 0 337251 0 0 0 0 610146 0 575022 0 0 299419 0 0 517997 0 0 395582 0 659517 0 0 431232 0 895766 0 0 0 902090 0 0 304460 0 293908 +AAELQYGELPR MGYG000000301_00104;MGYG000000133_01006 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3WH14@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 - 1.0 - 1.0 ko:K03695,ko:K03696 1.0 ko01100,ko04213,map01100,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N,UVR 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 MGYG000000301_00104 0.5 - - - - 1.0 1.0 1.0 1.0 Metabolic pathways|Longevity regulating pathway - multiple species 1.0 K03695:clpB; ATP-dependent Clp protease ATP-binding subunit ClpB|K03696:clpC; ATP-dependent Clp protease ATP-binding subunit ClpC 1.0 none 1.0 0 528275 347967 346129 0 0 0 0 0 0 0 0 208464 0 0 476039 0 0 0 0 0 389111 0 652970 0 0 0 0 0 0 502653 680440 529398 0 0 0 0 384649 0 280382 353591 331894 0 280795 0 0 0 0 0 0 198514 0 0 348662 0 0 0 0 0 241199 0 0 0 0 0 0 0 0 234450 0 0 0 0 0 0 329395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177792 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1772670 751652 997787 0 384433 0 0 0 0 0 0 813503 976404 0 1305118 0 0 0 0 0 1257208 0 957982 0 0 0 0 0 0 384045 1128906 1744609 0 0 0 0 427592 +AAELSGDFAELMKLADK MGYG000003221_00300 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__OM05-12|s__OM05-12 sp900760755|m__MGYG000003221 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000003221_00300 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 778135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAELSGDFAK MGYG000001306_00064 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001306_00064 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3131077 0 0 0 0 2110185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1479630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAELTR MGYG000000196_03698;MGYG000001666_00068;MGYG000001378_01448;MGYG000000243_01648;MGYG000002171_00496 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1904@1|root,COG1904@2|Bacteria,4NFHS@976|Bacteroidetes,2FMMW@200643|Bacteroidia 0.8 976|Bacteroidetes 1.0 G 1.0 glucuronate isomerase 0.8 uxaC 0.8 - 1.0 5.3.1.12 0.8 ko:K01812 0.8 ko00040,ko01100,map00040,map01100 0.8 M00061,M00631 0.8 R01482,R01983 0.8 RC00376 0.8 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 UxaC 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_03698 0.2 glucuronate isomerase. uronic isomerase. Also converts D-galacturonate to D-tagaturonate. D-glucuronate = D-fructuronate. 0.8 0.8 0.8 0.8 Pentose and glucuronate interconversions|Metabolic pathways 0.8 K01812:uxaC; glucuronate isomerase [EC:5.3.1.12] 0.8 none 1.0 0 0 0 1277643 0 0 1134098 0 1724931 1382397 0 0 0 917379 1323701 0 0 0 0 0 0 0 0 0 0 0 1949558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1228203 0 0 1093046 0 947021 1288260 0 0 0 1417421 356054 0 0 0 0 0 0 0 0 0 0 0 1533591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257228 0 0 114218 0 713241 335748 0 0 0 869520 357968 0 0 0 0 0 0 0 0 0 0 0 1175684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1477229 0 0 1420829 0 1292091 745512 0 0 0 883662 431232 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1237787 0 0 964713 0 0 0 1056173 953833 0 0 0 0 0 0 0 0 0 0 0 1449826 0 0 0 0 0 0 0 0 0 0 0 +AAELVQALK MGYG000000087_01479;MGYG000000198_02625 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,21YF6@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000087_01479 0.5 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 499920 0 0 399129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281632 0 0 0 0 0 0 0 0 0 0 273951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249915 0 0 208440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAELYKPFIIR MGYG000004797_04274;MGYG000001306_02654;MGYG000004561_01031;MGYG000000236_01798;MGYG000003693_02792;MGYG000002556_01323;MGYG000002478_00805;MGYG000001313_00088;MGYG000003374_00512 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000004797_04274 0.1111111111111111 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 81265 0 0 0 0 154852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417512 0 0 0 0 725220 0 0 0 0 528273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 206995 0 0 0 0 169804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88996 0 0 0 0 125050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222969 0 0 0 0 132010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEM(Met->Glu)NMPVER MGYG000002517_00980 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth 1.0 sigA 1.0 - 1.0 - 1.0 ko:K03086 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03021 1.0 - 1.0 - 1.0 - 1.0 Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00980 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03086:rpoD; RNA polymerase primary sigma factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1336192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 651621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 831982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2204344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 716227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEM(Oxidation)AATC(Carbamidomethyl)TDPVR MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 0.5 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 637150 1364065 745454 133042 1421562 1017507 0 889797 484438 857479 797095 680719 1713761 565355 1212470 3062098 1309766 0 915117 871334 570877 2400743 0 301186 863008 500175 386571 0 365118 556605 598704 1186692 395457 640642 412555 340874 390260 648134 1307390 1634987 0 817196 522417 689521 2181276 956080 2575821 670926 366443 675750 508666 507695 670584 157591 457236 0 905674 1571061 673498 472411 0 1388446 664288 1002217 1036682 0 1665406 703897 1582559 702055 334783 1516828 962937 1435989 1227631 627913 3988651 11812878 1113989 6856483 1016479 4172778 984192 3628160 1545152 3677743 1124393 2195616 3000995 3229279 4046380 3258500 3083856 0 4067119 4374083 2887848 5517012 0 2461739 4670496 3656170 4610673 0 675598 2726727 1184370 3949173 2047783 4324967 4764334 1359117 2999171 1019622 1887260 2020168 1223319 2560917 1590619 2192054 2649609 1544615 1442350 3555502 1402166 1117404 2158440 2144740 1733563 3087461 2431719 0 973896 2837189 1314039 1925983 0 2022265 1363292 777044 1895948 0 2374091 1485443 1409482 1372411 1549550 842804 1286218 1137146 908274 1288265 905366 1316966 1666660 1452951 2544964 1331405 1005714 1023417 995131 1333118 2689760 1279285 2730545 1172385 1247537 2117269 839772 0 1137643 1425125 801436 1772111 0 1596140 1354697 1673670 1263626 0 260919 1146666 2346809 1633839 2555189 1282646 1505345 1509593 1794762 1879893 +AAEM(Oxidation)AATC(Carbamidomethyl)TDPVRK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 0.5 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 0 236857 0 0 0 303737 0 179076 177932 173701 255267 0 369057 0 292618 938229 0 0 106477 325824 0 103229 0 0 196155 148034 0 0 0 0 0 386109 0 0 0 0 231392 274853 250402 365599 0 84386 0 171027 0 186235 538458 0 148442 0 0 208824 244209 0 0 0 129458 301254 0 0 0 323754 229640 155070 187015 0 0 0 0 90614 0 254897 291513 0 309186 0 1024866 2457122 204858 1175769 0 1242795 0 977115 438622 913639 242201 0 897848 859324 1016660 1018442 0 0 1078039 1212535 802373 1447986 0 540057 1128169 839963 760153 0 0 0 0 530370 554880 1154439 1059966 0 1074467 0 499869 384024 150350 556073 0 399317 0 340849 165812 610770 250966 0 370578 336237 0 580882 0 0 0 349534 133730 534533 0 379402 0 108298 275839 0 0 0 0 98395 550933 0 143632 0 0 367338 261601 267158 361992 277832 0 289975 0 141328 218378 237530 482421 0 520642 364086 271441 340582 0 0 252079 532457 0 331091 0 298024 294232 233316 168342 0 0 0 0 341716 471923 275462 299925 0 367493 436686 +AAEMAAN(Deamidated)LKPGEVMLLENLR MGYG000000074_02205 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,22UY0@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02205 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 48916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEMAATC(Carbamidomethyl)TDPVR MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 0.5 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 4848364 12519848 6902606 2593894 11181763 8175882 723189 7145550 2729799 6806702 6035253 6471701 11626039 3922466 7198047 10851839 4474640 0 6666564 6985287 4483886 11055031 0 2598580 7204431 3594625 3662852 0 3180637 3802476 3367531 9862548 4280315 4512217 4155916 2342793 2874511 4759579 15606924 15579945 3014269 8894575 4533341 7711306 25851789 9430359 9147738 6620102 3663094 4498382 5777079 6275171 8060691 2864121 5889425 0 13037907 17446116 8981920 6210795 0 14572066 9596861 10194741 10309817 0 19631262 7141278 10675086 6492717 3646347 13453491 10796680 15872101 10281955 3948006 34175803 37508260 7331492 41861599 4355514 27891079 7284479 26430166 11045220 25627267 10835621 15421803 24711774 21508737 37058398 24341755 21784273 0 34838571 39203463 24426938 47416241 0 17925597 42613578 29621973 37155248 0 6133672 20615843 7311560 28111656 14681615 34855712 32430149 8946713 23027855 5779403 15470313 15600272 8139840 19454848 13988926 19088089 23508200 12976159 11460395 24874011 10056071 6040126 17079682 13451114 11450080 27754831 21727054 0 8305093 23080440 10400350 12293071 0 11789050 11742536 5714161 14568042 0 15632593 12255374 8489705 9874783 13141288 5579877 12145193 9874320 7330831 9538297 9418074 12438857 18519999 10089904 371155 11652930 6428220 9758661 8086820 9877850 16074333 10471096 13629797 8062332 10606792 18191932 9912747 0 9522380 11618840 6597296 14331498 0 10011931 9506594 15164098 11155739 0 3150880 10090039 21935413 12723846 24030921 12636853 8612046 9905869 14007091 16788977 +AAEMAATC(Carbamidomethyl)TDPVRK MGYG000000077_00330;MGYG000000262_02730 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Pyruvate formate lyase-like 1.0 - 1.0 - 1.0 2.3.1.54,4.3.99.4 1.0 ko:K00656,ko:K20038 1.0 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 1.0 - 1.0 R00212,R06987 1.0 RC00004,RC01181,RC02742,RC02833 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00330 0.5 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 1.0 none 1.0 904940 2454838 1324573 598789 1546714 1555399 180695 1388551 0 1397336 1024207 0 2304689 747002 1200903 1821167 792543 0 1406845 1355281 939644 2130819 0 765294 1425484 834138 745343 0 186924 776783 671836 1435023 728228 915879 733757 487357 645027 935653 3021001 2318718 489504 1491629 866731 1511376 3773221 1649873 0 1342711 601814 0 1260603 1213380 1629020 580320 1045478 0 2015130 2756034 1934244 953772 0 2802120 1551929 1736747 1644865 0 2947585 1310104 1701358 1090311 698540 2323285 858112 2799398 1883728 666332 5917817 5486286 1266292 6922010 628589 4749716 1275452 6039794 0 5037197 1691835 0 4002855 3191378 5143410 3714925 4116413 0 6176491 5762671 3924410 6674881 0 3773647 6474287 5692759 7193891 0 1105040 3622417 1390617 5181585 2555336 6255483 3982355 1887886 3908403 1068474 2571417 1812985 1164853 2435196 1650429 2065279 3035233 1786063 0 3034367 1661637 0 2976477 2353378 1728671 3020141 1824694 0 1255632 2884491 1419875 1745022 0 1127581 1930978 935943 2202099 0 1545632 1780112 1038059 1426111 1564471 1008312 1749571 1615385 1219719 566954 2320649 2944503 3508872 2149836 4900512 2375311 1554944 2128141 0 2621793 3486397 0 2854851 944683 2274099 3935006 2148780 0 2161340 2270261 1390659 2911929 0 2186832 2108638 2842785 2050278 0 445469 2296408 4412309 2853943 3457978 2744981 1390617 2735108 2406424 3486390 +AAEMIAEAQYR MGYG000000074_00673;MGYG000002082_00353 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1729@1|root,COG1729@2|Bacteria,4NEM2@976|Bacteroidetes,2G3E7@200643|Bacteroidia,22UFS@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00673 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1094902 0 1962265 0 716178 673255 0 0 0 2220412 1466387 0 1109929 0 0 615901 933104 0 1409537 0 0 975538 0 1751192 885060 941776 0 0 934906 1096758 0 0 1225927 0 0 0 1172521 1915905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 419553 0 0 0 0 525186 416768 0 0 0 368443 0 0 0 0 0 352931 517365 0 742476 353725 0 393801 0 0 0 400498 0 0 534473 0 0 0 374425 0 0 0 409770 0 1595354 0 1406107 0 1994403 1935810 0 0 0 1614403 1041550 0 1481392 0 0 1744360 1661214 0 2257869 3367820 0 1536371 0 1505460 1553019 1635745 0 0 1605129 2409270 0 0 684352 0 0 1596918 2280457 2138477 +AAEN(Deamidated)GVELLYVNTAK MGYG000002966_03539;MGYG000002298_00579 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,248JR@186801|Clostridia,36H91@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 PFAM Alcohol dehydrogenase 1.0 - 1.0 - 1.0 - 1.0 ko:K19956 1.0 ko00051,map00051 1.0 - 1.0 R03234 1.0 RC00089 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002966_03539 0.5 - - - - 1.0 1.0 1.0 1.0 Fructose and mannose metabolism 1.0 K19956:sorE; L-sorbose 1-phosphate reductase [EC:1.1.1.-] 1.0 none 1.0 0 0 0 0 0 1940433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1789810 0 672112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 622861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2043407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1388429 0 1594428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAENAEGRPERPK MGYG000002517_01672 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002517_01672 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 144732 0 0 0 0 0 0 51945 0 0 0 0 0 0 425449 0 0 0 0 0 0 0 0 0 541440 55095 43729 0 0 0 0 0 0 0 0 22449 74746 0 66001 0 0 0 0 0 0 129383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 52976 2351094 0 0 0 0 0 0 0 0 144889 88879 0 0 0 0 0 0 0 0 54165 0 0 0 0 0 0 23033 0 0 0 0 0 0 0 0 0 107625 28072 67584 0 0 0 0 0 0 0 0 37398 86208 0 448007 0 0 0 0 0 0 765483 0 0 0 0 0 0 727983 0 0 0 0 0 0 0 0 0 828044 517692 792678 0 0 0 0 0 0 0 0 379127 502080 0 255443 0 0 0 0 0 0 408560 0 0 0 0 0 0 370192 0 0 0 0 0 0 0 0 0 402281 505984 115853 0 0 0 0 0 0 0 0 722756 544528 0 +AAENFQMFQDK MGYG000000781_02550;MGYG000004876_03507;MGYG000004797_01909;MGYG000002478_03727;MGYG000002455_04589 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,4AKZ7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Conserved protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1015 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000781_02550 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1139469 974621 552510 1366718 0 1110840 1520270 150966 1201148 0 0 849734 0 0 0 0 939219 245918 1076005 1093821 1188443 803559 327017 1380196 1069047 1175796 1431125 417771 1230251 987311 1343678 0 653928 0 0 1433527 1062627 652944 996231 846933 933924 1350033 0 0 1206165 946359 822395 0 0 1083442 0 1186212 0 0 747689 1103163 1705525 637123 709648 0 0 0 675864 0 935367 1224362 606315 0 0 0 814086 0 0 845043 0 0 548192 0 0 568807 0 0 989251 0 834774 0 0 730395 0 732952 0 0 448352 0 287793 576624 523789 0 0 0 669669 0 526272 0 558394 0 566539 0 0 233766 0 807049 371612 495714 444020 0 495212 176375 0 0 617252 0 490223 0 0 207899 0 357884 0 0 363831 0 658898 315454 664088 0 0 316583 496166 396034 521322 404249 302537 303194 340735 0 0 0 0 736679 319583 467631 981433 315133 619624 571917 0 867307 1036898 1583446 908276 0 0 604113 0 583934 0 0 680703 2274001 1542416 1578949 0 1002687 1939995 700760 1000111 936665 472730 1801417 836495 491529 495566 0 389557 1615422 0 600884 845901 712648 +AAENFR MGYG000000243_00365;MGYG000001789_00953;MGYG000000236_01636;MGYG000001346_03052;MGYG000001337_02576 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,4AKZ7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Conserved protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1015 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00365 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 828610 0 1330643 0 1228911 0 0 0 0 1251966 0 0 0 661150 0 1403392 0 0 557296 0 0 0 0 594181 0 0 1094121 0 0 0 0 0 0 0 0 0 0 0 915706 0 1199999 0 1282279 0 0 0 0 1469906 0 0 0 0 0 1092200 0 0 0 0 0 0 0 0 0 0 759785 0 0 0 0 0 0 0 0 0 0 0 994752 0 955289 0 1356161 0 0 0 0 1105847 0 0 0 512330 0 1029232 0 0 1240649 0 0 0 0 1542095 0 0 1541957 0 0 0 0 0 0 0 0 0 0 0 303755 0 572842 0 515855 0 0 0 0 527768 0 0 0 450845 0 633391 0 0 205083 0 0 0 0 360128 0 0 642117 0 0 0 0 0 0 0 0 0 0 0 518879 0 842127 0 565137 0 0 0 0 536954 0 0 0 441481 0 623623 0 0 314473 0 0 0 0 192549 0 0 446902 0 0 0 0 0 0 0 +AAENFR(Arg->Gln)MFQDK MGYG000000243_00365 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG4198@1|root,COG4198@2|Bacteria,4NGQH@976|Bacteroidetes,2FN23@200643|Bacteroidia,4AKZ7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Conserved protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1015 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00365 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 1216570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAENGVELLYVNTAK MGYG000002966_03539;MGYG000002298_00579 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1063@1|root,COG1063@2|Bacteria,1TQ60@1239|Firmicutes,248JR@186801|Clostridia,36H91@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 PFAM Alcohol dehydrogenase 1.0 - 1.0 - 1.0 - 1.0 ko:K19956 1.0 ko00051,map00051 1.0 - 1.0 R03234 1.0 RC00089 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002966_03539 0.5 - - - - 1.0 1.0 1.0 1.0 Fructose and mannose metabolism 1.0 K19956:sorE; L-sorbose 1-phosphate reductase [EC:1.1.1.-] 1.0 none 1.0 0 0 0 0 0 2422529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2544971 0 961528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 597105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2280954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAENTASVMPGYTHLQR MGYG000001300_00033 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,3WGBU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 argininosuccinate lyase 1.0 argH 1.0 - 1.0 4.3.2.1 1.0 ko:K01755 1.0 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 1.0 M00029,M00844,M00845 1.0 R01086 1.0 RC00445,RC00447 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ASL_C2,Lyase_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00033 1.0 argininosuccinate lyase. omega-N-(L-arginino)succinate arginine-lyase. - 2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K01755:argH, ASL; argininosuccinate lyase [EC:4.3.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 486248 0 0 0 0 0 0 0 0 0 0 560620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAENVQESTYAR MGYG000001421_01835 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__Dielma|s__Dielma fastidiosa|m__MGYG000001421 1.0 COG0747@1|root,COG0747@2|Bacteria 1.0 2|Bacteria 1.0 E 1.0 dipeptide transport 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001421_01835 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116455 0 0 0 0 0 0 0 0 130356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 870617 0 0 0 0 0 0 0 0 617978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2046111 0 0 0 0 0 0 0 0 2594694 0 0 0 0 0 0 0 0 +AAEPASC(Carbamidomethyl)PK MGYG000001789_01036;MGYG000000042_00377;MGYG000001783_02237;MGYG000000196_01365;MGYG000003363_02568;MGYG000002560_00879;MGYG000003202_01810;MGYG000000243_03283;MGYG000002478_02582 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1350@1|root,COG1350@2|Bacteria,4PKSY@976|Bacteroidetes,2FMFD@200643|Bacteroidia,4AN0W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine 1.0 trpB 1.0 - 1.0 4.2.1.20 1.0 ko:K06001 1.0 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 1.0 M00023 1.0 R00674,R02340,R02722 1.0 RC00209,RC00210,RC00700,RC00701,RC02868 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PALP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001789_01036 0.1111111111111111 tryptophan synthase. tryptophan synthetase. The alpha-subunit catalyzes the conversion of 1-C-(indol-3- yl)glycerol 3-phosphate to indole and D-glyceraldehyde 3-phosphate (this reaction was listed formerly as EC 4.1.2.8).-!-The indole migrates to the beta-subunit where, in the presence of pyridoxal 5'-phosphate, it is combined with L-serine to form L-tryptophan.-!-In some organisms this enzyme is part of a multifunctional protein that also includes one or more of the enzymes EC 2.4.2.18, EC 4.1.1.48, EC 4.1.3.27 and EC 5.3.1.24.-!-In thermophilic organisms, where the high temperature enhances diffusion and causes the loss of indole, a protein similar to the beta subunit can be found (EC 4.2.1.122).-!-That enzyme cannot combine with the alpha unit of EC 4.2.1.20 to form a complex. (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K06001:trpB; tryptophan synthase beta chain [EC:4.2.1.20] 1.0 none 1.0 0 0 739323 0 736806 0 0 0 0 0 0 0 474496 0 0 625329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 647320 0 0 0 0 956344 0 0 252892 0 0 0 0 0 0 0 0 0 489012 0 0 367451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188352 0 0 0 0 141595 0 0 272570 0 265014 0 0 0 0 0 0 0 414819 0 0 439837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163027 0 0 0 0 260244 0 0 240318 0 294021 0 0 0 0 0 0 0 206450 0 0 354521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204269 0 0 0 0 198867 0 0 0 0 305711 0 0 0 0 0 0 0 512310 0 0 476800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215613 +AAEPFAVEVK MGYG000001378_04614 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2FQVZ@200643|Bacteroidia,4APF4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 D 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_04614 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 270485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 616412 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6958364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13894059 0 13676602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEPVKAEKPAAK MGYG000001300_02529 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG3940@1|root,COG3940@2|Bacteria,1VAX9@1239|Firmicutes,24NY2@186801|Clostridia,3WKE6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Ricin-type beta-trefoil 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 RicinB_lectin_2 1.0 - 1.0 CBM13 1.0 CBM13 1.0 CBM13 1.0 MGYG000001300_02529 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 406539 297198 0 0 237804 0 0 0 0 0 0 0 0 0 0 0 0 531529 0 0 0 0 264546 0 0 0 0 0 0 0 329616 0 0 0 0 387714 0 0 619630 658525 0 0 998812 0 0 0 0 0 0 0 0 0 0 0 0 528211 0 0 0 0 742004 0 0 0 0 0 0 0 495732 0 0 0 0 591707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527180 0 0 0 243318 0 0 0 0 0 0 0 0 0 0 0 0 148487 0 0 0 0 430308 0 0 0 0 0 0 0 416915 0 0 0 0 446643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEQGYIDEIILPK MGYG000003693_02732;MGYG000000042_01219;MGYG000001306_00284 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4799@1|root,COG4799@2|Bacteria,4NEMJ@976|Bacteroidetes,2FNCD@200643|Bacteroidia,4ANBE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 2.1.3.15,6.4.1.3 1.0 ko:K01966 1.0 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 1.0 M00373,M00741 1.0 R01859 1.0 RC00097,RC00609 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 GH101 1.0 MGYG000003693_02732 0.3333333333333333 acetyl-CoA carboxytransferase. | propionyl-CoA carboxylase. PCCase. The enzyme catalyzes the transfer of a carboxyl group carried on a biotinylated biotin carboxyl carrier protein (BCCP) to acetyl-CoA, forming malonyl-CoA.-!-In some organisms this activity is part of a multi-domain polypeptide that includes the carrier protein and EC 6.3.4.14 (see EC 6.4.1.2).-!-Some enzymes can also carboxylate propanonyl-CoA and butanoyl-CoA (Cf. EC 6.4.1.3). | Also carboxylates butanoyl-CoA and catalyzes transcarboxylation. acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)- biotinyl-L-lysyl-[protein]. | ATP + hydrogencarbonate + propanoyl-CoA = (S)-methylmalonyl-CoA + ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01966:PCCB, pccB; propionyl-CoA carboxylase beta subunit [EC:6.4.1.3 2.1.3.15] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1482622 0 0 0 0 1769169 0 0 0 0 1355831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEQLEK MGYG000002506_04140;MGYG000002366_03975;MGYG000002494_02911 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0176@1|root,COG0303@1|root,KOG2371@2759|Eukaryota,KOG2772@2759|Eukaryota,3AHVW@33154|Opisthokonta,3BZ72@33208|Metazoa,3DEMK@33213|Bilateria,40QWN@6231|Nematoda,1M0KR@119089|Chromadorea,4171K@6236|Rhabditida 1.0 2759|Eukaryota 1.0 G 1.0 Transaldolase/Fructose-6-phosphate aldolase 1.0 CNX1G 1.0 - 1.0 2.10.1.1,2.2.1.2,2.7.7.75 1.0 ko:K00616,ko:K13168,ko:K15376 1.0 ko00030,ko00790,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04727,map00030,map00790,map01100,map01110,map01120,map01130,map01200,map01230,map04727 1.0 M00004,M00007 1.0 R01827,R09726,R09735 1.0 RC00002,RC00439,RC00604,RC03462 1.0 ko00000,ko00001,ko00002,ko01000,ko03041 1.0 - 1.0 - 1.0 - 1.0 AIRS,DRY_EERY,DUF1244,MoCF_biosynth,MoeA_C,MoeA_N,PgpA,Proteasome,RecA,TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04140 0.3333333333333333 molybdopterin molybdotransferase. | transaldolase. | molybdopterin adenylyltransferase. glycerone transferase. Catalyzes the insertion of molybdenum into the ene-dithiol group of molybdopterin.-!-In eukaryotes this reaction is catalyzed by the N-terminal domain of a fusion protein whose C-terminal domain catalyzes EC 2.7.7.75. | Catalyzes the activation of molybdopterin for molybdenum insertion.-!-In eukaryotes, this reaction is catalyzed by the C-terminal domain of a fusion protein that also includes EC 2.10.1.1.-!-Formerly EC 2.7.7.n5. adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin. | D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | ATP + H(+) + molybdopterin = adenylyl-molybdopterin + diphosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Folate biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|GABAergic synapse 1.0 K00616:TALDO1, talB, talA; transaldolase [EC:2.2.1.2]|K13168:CLASRP, SFRS16; CLK4-associating serine/arginine rich protein|K15376:GPHN; gephyrin [EC:2.10.1.1 2.7.7.75] 1.0 none 1.0 0 0 671665 0 903330 1360890 0 1271058 0 0 1154508 0 945631 843661 0 0 1216502 0 1381882 469106 1367368 2368000 0 0 0 1269888 0 0 1328544 1394275 0 0 0 1318174 0 0 1418333 1033914 3349097 0 5151285 0 5547514 7665139 0 3949425 3151246 4365370 2480944 0 3532335 3858964 0 0 6409678 0 6383722 3025202 4686402 8832366 0 7855329 0 4076028 0 0 5533795 4428401 3621769 0 3412713 4123210 0 0 2553917 0 1266657 0 795804 0 973981 1780937 0 2030593 1014932 1693553 741280 0 1404321 1229429 0 0 1176093 0 1525301 2184207 1937538 2114207 0 2620483 0 1211708 0 0 2018302 805414 935042 0 1390778 1868617 0 0 1300363 985929 0 0 0 0 0 1432533 0 1927431 0 0 0 0 921872 1080457 0 0 0 0 0 0 873180 2267279 0 1403466 0 0 0 0 0 0 1099301 0 0 0 0 0 0 1304761 1220404 0 814416 0 492564 477767 0 662305 1103587 923837 787201 0 915961 1896343 0 0 0 0 740979 0 1187823 0 0 953089 0 1480318 0 0 1741255 931697 974596 0 864979 1023590 0 0 0 874064 +AAEQLGEENLPK MGYG000000036_00872 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Pseudoruminococcus|s__Pseudoruminococcus massiliensis|m__MGYG000000036 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000036_00872 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEQLIR MGYG000002494_00656 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2980@1|root,COG2980@2|Bacteria,1N0JN@1224|Proteobacteria,1SAG4@1236|Gammaproteobacteria,3ZK9E@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 M 1.0 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane 1.0 lptE 1.0 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 1.0 - 1.0 ko:K03643 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.42.1 1.0 - 1.0 iECH74115_1262.ECH74115_0730,iECSP_1301.ECSP_0694,iECs_1301.ECs0679,iG2583_1286.G2583_0804,iZ_1308.Z0788 1.0 LptE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00656 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03643:lptE, rlpB; LPS-assembly lipoprotein 1.0 none 1.0 0 0 1836234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1230897 0 0 0 0 0 0 0 0 0 1500987 1198953 0 0 1140791 0 0 0 0 1928153 0 0 1425583 0 0 0 0 0 0 0 0 0 0 0 0 0 1260004 0 1516426 0 0 0 0 0 0 0 0 0 1343501 1451915 0 0 0 0 0 0 0 1331555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 917498 0 1059297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1176452 0 0 0 0 0 0 0 0 0 0 0 722493 1228813 0 0 0 0 0 0 0 0 +AAEQPGVK MGYG000004526_01663 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-103|s__CAG-103 sp000432375|m__MGYG000004526 1.0 COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,22ICD@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate:ferredoxin oxidoreductase core domain II 1.0 vorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00174 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFOR_II,POR_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004526_01663 1.0 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00174:korA, oorA, oforA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEQYDGK MGYG000002517_01705 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 basic membrane 1.0 tmpC 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01705 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07335:bmpA, bmpB, tmpC; basic membrane protein A and related proteins 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573930 0 0 0 0 0 0 0 0 0 0 474821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEQYPDIK MGYG000001300_01299 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,3WJKQ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 basic membrane 1.0 tmpC 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_01299 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07335:bmpA, bmpB, tmpC; basic membrane protein A and related proteins 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313261 0 293546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1408671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1642456 0 1660270 0 0 0 0 0 0 2266201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEQYVIDEYSK MGYG000002494_02584 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG3383@1|root,COG3383@2|Bacteria,1QTZB@1224|Proteobacteria,1T1JA@1236|Gammaproteobacteria,3XN7Y@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family 1.0 fdhF 1.0 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0015942,GO:0015944,GO:0016491,GO:0016651,GO:0016999,GO:0017144,GO:0019752,GO:0030151,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704 1.0 1.17.1.9,1.17.99.7 1.0 ko:K00123,ko:K22015 1.0 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 1.0 - 1.0 R00519 1.0 RC02796 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECBD_1354.ECBD_3953 1.0 Fer2_4,Fer4,Fer4_6,Fer4_7,Fer4_9,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02584 1.0 formate dehydrogenase. | formate dehydrogenase (acceptor). NAD(+)-formate dehydrogenase. | formate dehydrogenase O. The enzyme from most aerobic organisms is devoid of redox-active centers but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centers, flavin and a molybdenum center.-!-Together with EC 1.12.1.2, forms a system previously known as formate hydrogenlyase.-!-Formerly EC 1.2.1.2. | Formate dehydrogenase H is a cytoplasmic enzyme that oxidizes formate without oxygen transfer, transferring electrons to a hydrogenase.-!-The two enzymes form the formate-hydrogen lyase complex.-!-The enzyme contains a selenocysteine residue.-!-Formerly EC 1.1.99.33 and EC 1.17.99.7. formate + NAD(+) = CO2 + NADH. | A + formate + H(+) = AH2 + CO2. 1.0 1.0 1.0 1.0 Glyoxylate and dicarboxylate metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00123:fdoG, fdhF, fdwA; formate dehydrogenase major subunit [EC:1.17.1.9]|K22015:fdhF; formate dehydrogenase (hydrogenase) [EC:1.17.98.4 1.17.98.-] 1.0 none 1.0 0 0 0 0 0 344278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 729641 0 818947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1449718 0 1942082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAERIDVDETGK MGYG000001689_00148;MGYG000001338_00681;MGYG000004735_00336 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Belongs to the formate--tetrahydrofolate ligase family 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001689_00148 0.3333333333333333 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01938:fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437433 0 0 0 0 0 0 0 +AAERNPEIAIQYK MGYG000002478_01152 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG2268@1|root,COG2268@2|Bacteria,4NIH3@976|Bacteroidetes,2FNXI@200643|Bacteroidia,4AP1M@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SPFH Band 7 PHB domain protein 1.0 yqiK 1.0 - 1.0 - 1.0 ko:K07192 1.0 ko04910,map04910 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03036,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Band_7,Flot 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01152 1.0 - - - - 1.0 1.0 1.0 1.0 Insulin signaling pathway 1.0 K07192:FLOT; flotillin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAERYAYVAK MGYG000003266_01415;MGYG000001642_00536 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CURX@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 alcohol dehydrogenase 1.0 adh1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003266_01415 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAES(Deoxy[S](Ser->Ala)YFLLAEAK MGYG000001835_02184;MGYG000003363_01544 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001835_02184 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 933154 0 0 0 0 0 0 0 0 0 0 388755 0 1599306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 679618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAESAAQAQNEK MGYG000001346_00694;MGYG000004899_00787 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0845@1|root,COG0845@2|Bacteria,4NECC@976|Bacteroidetes,2FMDD@200643|Bacteroidia,4ANZR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Auxiliary transport protein, membrane fusion protein (MFP) family protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01993 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_00694 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01993:ABC-2.TX; HlyD family secretion protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 451645 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 576770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 719594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAESGEVVEGDVTEFNK MGYG000002223_00230;MGYG000002040_01384;MGYG000002272_02217;MGYG000002610_00834;MGYG000000911_00719;MGYG000001300_00580;MGYG000000039_01115;MGYG000001255_00085;MGYG000002641_00839;MGYG000003291_01006;MGYG000000195_02259 domain d__Bacteria 1.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3WGII@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 IJM 1.0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002223_00230 0.09090909090909091 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1|K03527:ispH, lytB; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] 1.0 none 1.0 1133281 981503 843487 1650509 153449 850055 1062039 574584 1269197 798664 757990 857974 902825 864562 907175 1046437 1239665 2376809 1197932 1225454 567847 884278 2298259 1056745 820330 1138330 1063081 2042043 638542 1021454 932303 783260 1006886 1359841 731138 1424516 1067730 862096 2601591 2275980 2645193 2968473 1331590 2418993 3091436 1567728 3546819 782305 1792791 3082056 1943136 3526158 2440682 2528823 2972551 5294514 3930372 3035707 1806442 1847616 5766128 2468723 3557378 2909002 2619190 5173419 813615 2273347 2205361 1996524 2545211 2327766 1218593 2422388 2467001 2514752 580419 418582 504181 341737 581051 256864 879020 414503 596563 526190 706952 561735 312295 622194 648694 476938 171669 2991432 415188 378104 697391 398397 2994822 361465 461082 657677 370712 2888425 470992 533520 518792 333615 543439 550349 414601 619392 611380 574160 1077997 1616311 1727816 1718421 1384784 2054248 2362297 946434 1334438 1040929 1608033 2320348 1759961 1434138 929377 1582569 1261682 2733281 1642323 1743500 1731618 1965264 1957869 1725415 1433530 1254816 1035132 1981418 687595 1672438 2122358 1476013 1693983 1378461 544860 1320175 1212372 1796832 0 256528 403594 0 203022 0 0 448301 0 0 0 0 288242 0 0 257858 0 3904776 0 171365 0 200805 4321513 0 0 0 250677 5059401 0 0 284774 281024 503977 349781 216594 0 0 487692 +AAESGEVVEGDVTEFNKGGVVVNVK MGYG000002040_01384;MGYG000002272_02217;MGYG000001300_00580;MGYG000000039_01115;MGYG000001255_00085 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3WGII@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 IJM 1.0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002040_01384 0.2 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1|K03527:ispH, lytB; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] 1.0 none 1.0 616943 843000 1182824 943840 0 780067 732978 0 692708 0 1049254 634881 0 879125 613454 692135 1156287 1553744 805744 704457 301897 878415 1469437 855169 711206 507710 715484 1934990 0 0 1095547 0 1182989 991825 0 0 645700 982347 562646 469219 620887 626703 0 659437 706077 0 721482 0 658470 635006 0 719241 840092 583938 1013912 771717 831747 547544 476839 845735 711094 488796 871384 626943 722832 876723 0 0 742180 0 517022 783775 0 0 630195 635949 0 355384 648377 451081 0 605095 325640 0 494617 0 374418 0 0 0 0 350396 696301 708115 417787 0 242828 308020 924714 289363 273505 372765 288809 926534 0 0 244982 0 320668 292624 0 0 310149 254688 523888 508595 1064335 532667 0 897173 768782 0 650974 0 666017 1143017 0 633979 592250 569209 574371 736362 749544 545059 1049528 773990 1608343 801483 701067 698942 659511 687192 0 0 713487 0 839574 891489 0 0 694098 730119 208610 0 263141 0 0 191956 0 0 228133 0 249693 0 0 0 273107 266434 300329 1078279 299833 224945 242339 0 740240 207406 255557 161358 224537 1011614 0 0 318945 0 254374 0 0 0 370541 308734 +AAESGLSKADAK MGYG000000243_01852 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia,4ARQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01852 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 0 0 988941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1022115 0 0 0 0 796642 0 0 627987 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 126439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139439 0 0 0 0 184008 0 0 153780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121766 0 0 0 0 327619 0 0 327303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 78369 0 0 0 0 508268 +AAESINLN(Deamidated)GTPAGK MGYG000002492_00017 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Phosphotransferase System 1.0 fruA 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 GGDEF,PTS_EIIA_2,PTS_EIIC,PTS_IIB,Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00017 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Phosphotransferase system (PTS) 1.0 K02768:fruB; fructose PTS system EIIA component [EC:2.7.1.202]|K02769:fruAb; fructose PTS system EIIB component [EC:2.7.1.202]|K02770:fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 712718 0 0 0 0 0 0 0 0 0 541563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 630545 0 0 0 0 432210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAESINLNGTPAGK MGYG000002492_00017 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Phosphotransferase System 1.0 fruA 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 GGDEF,PTS_EIIA_2,PTS_EIIC,PTS_IIB,Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00017 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Phosphotransferase system (PTS) 1.0 K02768:fruB; fructose PTS system EIIA component [EC:2.7.1.202]|K02769:fruAb; fructose PTS system EIIB component [EC:2.7.1.202]|K02770:fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348101 0 0 0 0 360710 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 716077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 914851 0 0 0 0 697326 0 0 1826955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306300 0 0 0 0 462224 0 0 0 0 0 0 0 0 0 0 0 0 373475 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564210 +AAESNPAIAIQYK MGYG000002717_01620;MGYG000004876_02300;MGYG000003312_01422;MGYG000000013_00587;MGYG000002561_00344;MGYG000000196_00432;MGYG000003701_03766;MGYG000001378_02290;MGYG000003351_02442;MGYG000004899_00490;MGYG000000243_00077;MGYG000002549_00282;MGYG000002470_01608;MGYG000000236_03206;MGYG000002281_04177;MGYG000000054_00015;MGYG000001345_01047 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2268@1|root,COG2268@2|Bacteria,4NIH3@976|Bacteroidetes,2FNXI@200643|Bacteroidia,4AP1M@815|Bacteroidaceae 0.9411764705882353 976|Bacteroidetes 1.0 S 1.0 SPFH Band 7 PHB domain protein 0.9411764705882353 yqiK 1.0 - 1.0 - 1.0 ko:K07192 1.0 ko04910,map04910 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03036,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Band_7,Flot 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002717_01620 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 Insulin signaling pathway 1.0 K07192:FLOT; flotillin 1.0 none 1.0 1634741 1643036 2034918 2078718 1775838 1727118 2186904 1846143 1631330 1765742 1570621 1505809 1743405 1757970 1870096 1950604 1802330 860689 1396836 1892371 1796097 1411470 921385 1787854 1975201 1959849 1570665 740577 1491763 1613989 1620034 1583394 2147354 2195498 1725127 1718492 1615981 2255345 1776095 0 0 2180296 0 0 1740955 1751426 1755671 2010001 0 1176789 0 1769006 1176333 1741540 1027863 0 1392576 1802709 1188088 2225773 1904393 0 1496274 1929526 2036685 0 0 1334832 0 1071338 2272265 1735079 1536352 1685261 1649286 0 901406 1468085 1747142 755239 1274990 1027252 999412 1353113 1392109 1343953 1075068 1504573 1593760 1144288 1470775 1862568 1327178 932451 1471411 1083843 823474 1595002 1118681 966058 769152 731846 851600 1362624 1056192 1271579 1254420 1040712 0 1582112 1605026 900758 1434871 1745418 646793 919797 733998 762279 805483 993877 705310 652196 684527 896314 1002869 611849 917817 691211 731738 1159024 729107 744185 714649 727540 754329 1236283 611797 1029301 729967 697985 827933 727958 1018179 688387 649948 715644 814770 615598 814685 832964 813183 609287 495754 542245 600680 506865 312071 746001 1078741 424087 232929 582803 630173 397461 918252 413060 385228 754785 425286 945081 225081 657650 583028 553821 738925 699376 551678 344823 467680 865313 429144 823917 622323 842619 515855 478585 0 333707 819938 355761 +AAESRPAPFLIHQESNVIVR MGYG000002494_01208 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1530@1|root,COG1530@2|Bacteria,1MV65@1224|Proteobacteria,1RMDS@1236|Gammaproteobacteria,3WWD0@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs 1.0 rne 1.0 GO:0000287,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008312,GO:0008995,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0017151,GO:0019222,GO:0019439,GO:0019899,GO:0022607,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043462,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048519,GO:0050789,GO:0050790,GO:0051095,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902280 1.0 3.1.26.12 1.0 ko:K08300 1.0 ko03018,map03018 1.0 M00394 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko03009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PNPase_C,RNase_E_G,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01208 1.0 ribonuclease E. RNase E. RNase E is a bacterial ribonuclease that plays a role in the processing of ribosomal RNA (9S to 5S rRNA), the chemical degradation of bulk cellular RNA, the decay of specific regulatory, messenger and structural RNAs and the control of plasmid DNA replication.-!-The enzyme binds to monophosphorylated 5' ends of substrates but exhibits sequential cleavages in the 3' to 5' direction.-!-2'-O-methyl nucleotide substitutions at RNase E binding sites do not prevent binding but do prevent cleavage of non-modified target sequences 5' to that locus.-!-In Escherichia coli, the enzyme is found in the RNA degradosome.-!-The C-terminal half of the protein contains binding sites for the three other major degradosomal components, the DEAD-box RNA helicase Rh1B, EC 4.1.1.11 and EC 2.7.7.8.-!-Formerly EC 3.1.26.n1. Endonucleolytic cleavage of single-stranded RNA in A- and U-rich regions. 1.0 1.0 1.0 1.0 RNA degradation 1.0 K08300:rne; ribonuclease E [EC:3.1.26.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 689489 0 388571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAESVLM(Oxidation)EIVR MGYG000001521_00864;MGYG000002154_00941;MGYG000004833_01068;MGYG000001563_00272;MGYG000001541_01134;MGYG000000185_01922;MGYG000001506_00184 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 E 1.0 Beta-eliminating lyase 1.0 tnaA 1.0 - 1.0 4.1.99.1 1.0 ko:K01667 1.0 ko00380,map00380 1.0 - 1.0 R00673 1.0 RC00209,RC00355 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Beta_elim_lyase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001521_00864 0.14285714285714285 tryptophanase. TNase. The enzyme cleaves a carbon-carbon bond, releasing indole and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-Also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine and other 3-substituted amino acids. H2O + L-tryptophan = indole + NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 Tryptophan metabolism 1.0 K01667:tnaA; tryptophanase [EC:4.1.99.1] 1.0 none 1.0 0 373614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1080395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAESVLMEIVK(Lys->Arg) MGYG000002057_00764;MGYG000002944_00213;MGYG000002993_00539;MGYG000002036_00786;MGYG000001632_01270 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia 0.8 186801|Clostridia 1.0 E 1.0 Beta-eliminating lyase 1.0 tnaA 1.0 - 1.0 4.1.99.1 1.0 ko:K01667 1.0 ko00380,map00380 1.0 - 1.0 R00673 1.0 RC00209,RC00355 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Beta_elim_lyase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002057_00764 0.2 tryptophanase. TNase. The enzyme cleaves a carbon-carbon bond, releasing indole and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-Also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine and other 3-substituted amino acids. H2O + L-tryptophan = indole + NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 Tryptophan metabolism 1.0 K01667:tnaA; tryptophanase [EC:4.1.99.1] 1.0 none 1.0 1374335 0 0 0 424992 967949 0 0 0 0 1162691 2111576 0 598804 262262 0 0 0 0 0 0 1533283 0 0 699599 0 0 0 0 1037316 0 0 550975 692858 0 0 681867 656428 0 0 2647895 5195959 4082015 0 0 364227 2439131 0 3341424 0 0 0 3696661 0 0 0 4592162 0 0 3756712 0 0 3450334 0 5157660 0 0 0 0 0 1987684 3232361 0 0 2906338 1836045 2373035 0 0 0 0 0 0 0 1625900 2306147 0 2282745 0 1918735 0 0 0 0 2447194 0 0 0 0 0 1883046 2188151 2454437 0 0 0 0 0 2092173 0 0 0 2012889 1488038 984363 0 818224 1022448 885714 903620 686516 0 753272 1014916 937859 679922 0 1154196 697567 0 0 0 758337 1093869 0 1089809 0 1122736 803205 612888 967474 0 0 949605 0 0 0 426603 0 0 626236 920669 2239137 0 0 3513530 2292667 2115049 2874202 2967347 2178346 3407981 2554097 2094463 0 3113340 2608986 0 0 0 3066940 0 0 2422682 0 1913899 2914194 2524435 0 0 0 3365522 0 0 0 3487848 0 0 3122540 2826824 +AAESVLMEIVKK MGYG000002057_00764;MGYG000003753_00223;MGYG000002944_00213;MGYG000002993_00539;MGYG000003770_02347;MGYG000001632_01270 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 E 1.0 Beta-eliminating lyase 1.0 tnaA 1.0 - 1.0 4.1.99.1 1.0 ko:K01667 1.0 ko00380,map00380 1.0 - 1.0 R00673 1.0 RC00209,RC00355 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Beta_elim_lyase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002057_00764 0.16666666666666666 tryptophanase. TNase. The enzyme cleaves a carbon-carbon bond, releasing indole and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-Also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine and other 3-substituted amino acids. H2O + L-tryptophan = indole + NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 Tryptophan metabolism 1.0 K01667:tnaA; tryptophanase [EC:4.1.99.1] 1.0 none 1.0 902908 0 1037842 0 689798 936192 1239822 1378185 1266948 0 0 598447 0 0 1017041 0 1103028 711464 0 705942 597168 849425 714768 879559 784626 1135692 0 871197 1249702 790695 1041988 0 952024 0 0 0 1015491 793783 44999 0 72504 0 172042 92011 84152 73746 65518 0 0 54033 0 0 9913914 0 94748 121448 0 132181 67962 127569 0 67807 62050 88486 0 97990 159523 59450 0 0 52708 0 0 0 120761 89132 408646 0 166534 0 257763 377690 338620 430588 356899 0 0 501048 0 0 378264 0 400843 671132 0 354864 332058 399609 708843 401426 282905 198002 0 506535 401384 391996 463610 0 303203 0 0 0 412471 312947 565778 0 672860 0 623201 806968 944346 751336 653955 0 0 461605 0 0 452718 0 594933 834438 0 753412 1736083 664064 651564 676963 1651207 760866 0 741093 568459 520774 677151 0 648754 0 0 0 575690 630246 0 0 0 0 120091 0 563329 0 0 0 0 195745 0 0 0 0 0 150442 0 0 0 0 123240 180983 0 0 0 199517 833635 0 0 0 301677 0 0 0 0 0 +AAESVLMEIVR MGYG000001521_00864;MGYG000002154_00941;MGYG000004833_01068;MGYG000001563_00272;MGYG000001541_01134;MGYG000000185_01922;MGYG000001506_00184 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG3033@1|root,COG3033@2|Bacteria,1TRGV@1239|Firmicutes,248WC@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 E 1.0 Beta-eliminating lyase 1.0 tnaA 1.0 - 1.0 4.1.99.1 1.0 ko:K01667 1.0 ko00380,map00380 1.0 - 1.0 R00673 1.0 RC00209,RC00355 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Beta_elim_lyase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001521_00864 0.14285714285714285 tryptophanase. TNase. The enzyme cleaves a carbon-carbon bond, releasing indole and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia.-!-The latter reaction, which can occur spontaneously, can also be catalyzed by EC 3.5.99.10.-!-Also catalyzes 2,3-elimination and beta-replacement reactions of some indole-substituted tryptophan analogs of L-cysteine, L-serine and other 3-substituted amino acids. H2O + L-tryptophan = indole + NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 Tryptophan metabolism 1.0 K01667:tnaA; tryptophanase [EC:4.1.99.1] 1.0 none 1.0 0 0 0 0 0 0 280639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1076564 0 0 0 3805436 3613155 349834 0 0 4180664 5401631 5584461 0 0 0 3318919 0 0 0 2448969 3852143 0 0 4649194 3223353 4672603 0 4505248 0 3487552 0 0 0 0 5128522 0 0 0 3455969 3402138 0 0 0 3227608 1615720 2062028 0 1894847 1776461 2177076 0 0 0 0 0 0 0 2338907 0 662559 0 2438343 0 2431718 0 0 0 0 0 1523650 2060946 0 0 0 0 0 0 1515742 0 0 0 0 0 0 0 0 0 672157 0 0 0 0 0 0 0 0 0 407295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 930904 0 0 0 0 0 0 2481941 2431511 0 0 0 0 0 0 0 0 0 0 0 0 0 2541929 0 0 2521811 0 0 1634964 0 0 0 0 0 4028910 0 0 0 3448065 0 0 2950625 0 0 +AAESVLVC(Carbamidomethyl)VSGR MGYG000002274_01087;MGYG000002641_01949;MGYG000002040_00027;MGYG000004679_00212;MGYG000002545_01805;MGYG000001300_02656;MGYG000003291_01552 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 translation elongation 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_01087 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 597010 0 613358 723313 0 676679 0 0 504974 0 694613 569106 0 0 500818 0 0 1171428 0 867054 0 483166 999946 645448 541648 659280 0 1252743 0 0 0 0 1345775 464618 0 0 557751 748878 1230136 0 748882 1278772 0 773278 0 0 1030716 0 1190165 983202 0 0 1275671 0 0 1370162 0 1230606 0 852046 1148520 891486 1392901 1093102 0 1294090 0 0 0 0 642117 873631 0 0 853585 682654 398384 0 5815261 764909 0 590139 0 0 644988 0 744319 763720 0 0 368730 0 0 1779143 0 393971 0 542679 1859388 536895 460870 560460 0 1873946 0 0 0 0 3323243 603372 0 0 514650 1723432 604378 0 712099 656125 0 595616 0 0 627494 0 568782 822769 0 0 628004 0 0 519274 0 871929 0 497004 1034602 518415 567303 831542 0 655672 0 0 0 0 528969 499263 0 0 661881 420506 0 0 573673 525010 0 769242 0 0 270714 0 471522 809100 0 0 462035 0 0 1949922 0 1079745 0 418770 2603817 532579 562089 987642 0 2734375 0 0 0 0 361024 0 0 0 843282 733344 +AAESYFLLAEAK MGYG000001835_02184;MGYG000003363_01544 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 2EXHN@1|root,33QTW@2|Bacteria,4NK9F@976|Bacteroidetes,2G0CT@200643|Bacteroidia,4AW68@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Susd and RagB outer membrane lipoprotein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001835_02184 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629117 0 0 0 0 0 0 0 0 0 1027335 0 0 599584 545659 0 753868 0 0 0 0 0 0 555028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 963340 0 0 0 0 709990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAETAMDVTTK MGYG000000077_02467;MGYG000000262_02234 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,25USM@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02467 0.5 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 261791 0 0 0 299753 0 0 0 514133 0 0 314347 0 521487 345654 0 0 486655 405891 0 584532 0 0 525337 0 228665 0 0 0 0 0 0 250605 453302 0 400553 0 544875 1118767 0 0 0 1117228 373227 0 0 0 0 0 442980 0 0 385323 914380 0 1382656 592480 0 1157221 0 287319 277670 271093 646096 0 0 640281 0 0 0 0 0 0 0 0 1135150 733705 0 0 0 641947 249575 0 0 1141239 0 0 687507 0 1365034 668351 453929 0 1452287 1126833 0 1105849 0 343462 1310749 905782 1373588 0 0 622934 0 0 0 1174984 1219089 0 935633 0 1197739 1630549 0 0 0 1970845 1698118 0 0 2012192 0 0 1391508 0 933924 2387730 1805236 0 904377 1685245 0 1566305 0 1757748 802725 375591 1211308 0 0 1305980 0 0 0 392400 1072438 0 682634 0 0 0 0 0 0 312230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167555 0 +AAETAVAGR MGYG000002517_00489 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 lipid kinase, YegS Rv2252 BmrU family 1.0 dagK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DAGK_cat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00489 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267514 0 0 0 0 365590 0 0 0 0 328341 425807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335577 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54496 0 0 0 0 0 0 816350 727873 0 0 0 0 0 489352 0 0 0 0 687824 0 0 0 0 753000 481620 0 0 0 0 0 0 0 0 463966 0 631061 0 1029359 0 0 0 0 0 0 883020 758866 0 0 0 0 0 770944 0 0 0 0 1153602 0 0 0 0 691187 660564 0 0 0 0 0 0 0 0 978063 0 1072909 0 694940 0 0 0 0 0 0 523139 808036 0 0 0 0 0 818805 0 0 0 0 381289 0 0 0 0 1265355 1453250 0 0 0 0 0 0 0 0 1162192 0 1500135 0 +AAETDIIPR MGYG000001338_01246 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3XZKB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000001338_01246 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1158628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247967 0 0 0 0 0 0 +AAETLNNLR MGYG000002517_02001 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia 1.0 186801|Clostridia 1.0 NT 1.0 methyl-accepting chemotaxis protein 1.0 - 1.0 - 1.0 - 1.0 ko:K03406 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 MCPsignal,sCache_3_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02001 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03406:mcp; methyl-accepting chemotaxis protein 1.0 none 1.0 586769 0 243955 490450 300618 0 0 0 493690 476689 0 320482 0 0 0 0 0 0 596138 500604 0 0 0 0 355233 442416 349919 0 0 148590 0 0 532698 553331 346630 473646 411124 0 154453 0 451117 0 400403 0 0 0 0 383240 0 796721 0 0 144803 0 0 0 400422 0 0 0 0 0 0 0 0 0 0 431138 0 0 711387 0 0 0 0 479011 749486 0 287747 0 0 0 0 0 0 338823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343015 0 0 0 0 270519 0 0 0 0 577872 0 373973 204926 1830347 0 206342 2402871 2151464 0 0 1623944 1902477 3871329 0 1671777 0 0 2032765 0 0 0 1951968 2050676 0 0 0 0 1717023 1932813 1547383 0 0 2180826 0 0 507839 1458612 1434348 1616505 2595754 0 617689 0 861701 0 907986 0 0 557628 592676 1049952 0 504368 0 0 1080679 0 0 0 715252 868988 0 0 0 0 1101854 655268 486014 0 0 708287 0 0 799411 1074018 659316 1093889 458281 688415 +AAETLPDGVQIVK MGYG000003352_01343 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella|s__Parasutterella sp900766055|m__MGYG000003352 1.0 COG3118@1|root,COG3118@2|Bacteria,1MZBB@1224|Proteobacteria,2VSHX@28216|Betaproteobacteria 1.0 28216|Betaproteobacteria 1.0 O 1.0 Belongs to the thioredoxin family 1.0 trxA 1.0 - 1.0 - 1.0 ko:K03671 1.0 ko04621,ko05418,map04621,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 Thioredoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003352_01343 1.0 - - - - 1.0 1.0 1.0 1.0 NOD-like receptor signaling pathway|Fluid shear stress and atherosclerosis 1.0 K03671:TXN, trxA; thioredoxin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2141982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAETLVATHPDLAAR MGYG000001300_00314 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1305@1|root,COG1305@2|Bacteria,1TT33@1239|Firmicutes,24B27@186801|Clostridia,3WPMU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 Transglutaminase-like superfamily 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Transglut_core 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00314 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 253041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 712633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAETMAGLSGTR MGYG000001567_01031;MGYG000003096_00465;MGYG000002919_01788;MGYG000001642_00466;MGYG000003266_01691 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0549@1|root,COG0549@2|Bacteria,2HWQ6@201174|Actinobacteria,4CUT3@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Belongs to the carbamate kinase family 1.0 arcC 1.0 - 1.0 2.7.2.2 1.0 ko:K00926 1.0 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 1.0 - 1.0 R00150,R01395 1.0 RC00002,RC00043,RC02803,RC02804 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 AA_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001567_01031 0.2 carbamate kinase. - The enzyme catalyzes the reversible conversion of carbamoyl phosphate and ADP to ATP and carbamate, which hydrolyzes to ammonia and hydrogen carbonate.-!-The physiological role of the enzyme is to generate ATP. ATP + hydrogencarbonate + NH4(+) = ADP + carbamoyl phosphate + H(+) + H2O. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Purine metabolism|Nitrogen metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00926:arcC; carbamate kinase [EC:2.7.2.2] 1.0 none 1.0 951269 0 0 0 0 668569 0 0 0 0 0 0 0 0 1199272 0 0 0 0 0 0 656023 0 348787 1439809 637287 0 0 0 0 0 0 0 0 0 0 698065 0 1429555 0 0 0 0 1216945 0 0 0 0 0 0 0 0 850729 0 0 0 0 0 0 333440 0 1680921 1415790 1116547 0 0 0 0 0 0 0 0 0 0 1535949 0 1044977 0 0 0 0 385537 0 0 0 0 0 0 0 0 981001 0 0 0 0 0 0 1030923 0 0 862859 689490 0 0 0 0 0 0 0 0 0 0 817762 0 221208 0 0 0 0 377552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546618 0 662959 0 143825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 566024 0 0 0 0 0 0 0 0 0 622428 348654 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVA(Ala->Thr)LVGTEK MGYG000000212_01004;MGYG000003012_02042;MGYG000004733_01677;MGYG000000301_01355;MGYG000002298_00042;MGYG000004785_00406;MGYG000000806_00431;MGYG000002298_02777;MGYG000000142_01603;MGYG000000031_02920;MGYG000000171_01277 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01004 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3471829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3478255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3107735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563621 0 0 0 0 0 0 0 0 +AAEVAAQAAK MGYG000002445_00877 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp003024715|m__MGYG000002445 1.0 COG1788@1|root,COG1788@2|Bacteria,1UYH2@1239|Firmicutes,24CPB@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit 1.0 gctA 1.0 - 1.0 2.8.3.12 1.0 ko:K01039 1.0 ko00643,ko00650,ko01120,map00643,map00650,map01120 1.0 - 1.0 R04000,R05509 1.0 RC00012,RC00131,RC00137 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002445_00877 1.0 glutaconate CoA-transferase. - Glutarate, (R)-2-hydroxyglutarate, propenoate and propanoate, but not (Z)-glutaconate, can also act as acceptors. acetyl-CoA + trans-glutaconate = (2E)-glutaconyl-CoA + acetate. 1.0 1.0 1.0 1.0 Styrene degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01039:gctA; glutaconate CoA-transferase, subunit A [EC:2.8.3.12] 1.0 none 1.0 0 0 0 0 903652 751117 0 1278128 0 1535449 1527906 0 0 0 1862913 1051760 0 0 0 0 0 1318144 0 1031690 2168262 0 1194246 0 0 1214837 0 0 0 1640435 0 0 0 0 0 0 0 0 552591 767633 0 618511 0 0 642053 0 0 0 738754 604372 0 0 0 0 0 801794 0 1014743 676659 0 832161 0 0 651282 0 0 0 598056 0 0 0 0 0 0 0 0 630405 1001100 0 1050181 0 1437056 930402 0 0 0 1609018 1105625 0 0 0 0 0 1246666 0 1077018 1229828 0 1427044 0 0 851673 0 0 0 1998143 0 0 0 0 0 0 0 0 707201 667877 0 503519 0 506296 886666 0 0 0 397329 588021 0 0 0 0 0 704896 0 959916 503708 0 469923 0 0 422394 0 0 0 483551 0 0 0 0 0 0 0 0 396414 472201 0 514770 0 974438 1183085 0 0 0 842589 716597 0 0 0 0 0 582541 0 1047288 1218161 0 1023628 0 0 401538 0 0 0 1002932 0 0 0 0 +AAEVAEAIR MGYG000000090_02779 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter sp014287875|m__MGYG000000090 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,2690F@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000090_02779 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVAGKPYEDLK MGYG000000233_01457 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,21XHV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_01457 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 620994 0 145745 559550 310097 0 591736 777446 551178 505297 0 0 0 357460 0 0 143318 0 554874 565839 0 0 0 0 0 246497 172166 0 650608 0 0 0 248435 704718 0 541389 318098 288469 1100824 0 675218 1869235 854095 0 1150814 1563220 1148702 1240777 0 0 0 1084090 0 0 946121 0 869405 940681 0 0 0 0 0 968473 1015977 0 1188231 0 0 0 1053177 1332449 0 958599 792265 935711 388710 0 111354 546364 323682 0 539149 627842 435974 573444 0 0 0 260025 0 0 411420 0 658787 184113 0 0 0 0 0 564005 548731 0 507607 0 0 0 243262 644198 0 319977 471354 329623 792559 0 703333 922145 687502 0 1032911 976614 284144 878916 0 0 0 504828 0 0 439026 0 925379 241010 0 0 0 0 0 895785 276170 0 406898 0 0 0 773447 317609 0 887476 339109 459704 152477 0 240572 355151 178545 0 208328 170550 302134 209165 0 0 0 182192 0 0 71823 0 277351 0 0 0 0 0 0 471224 110811 0 339678 0 0 0 262805 216030 0 134517 279614 200748 +AAEVALVGTEK MGYG000000212_01004;MGYG000003012_02042;MGYG000004733_01677;MGYG000000301_01355;MGYG000002298_00042;MGYG000004785_00406;MGYG000000806_00431;MGYG000002298_02777;MGYG000000142_01603;MGYG000000031_02920;MGYG000000171_01277 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01004 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 4965577 4673807 0 5572025 7250017 2474741 5449012 3544679 4904576 7364764 5780755 5241695 1782775 5691817 5234296 6427989 8014938 4422783 0 4705103 5512793 5482812 3883600 5406625 3283691 3671135 6334441 6701846 4597286 4084830 4500830 4659082 1197142 4781061 1288255 3416466 5156185 2958730 3989244 1814000 2491078 2462508 1758500 2758201 2957781 2316019 1324405 2578196 1642320 2275880 2064664 1716754 1532077 2772076 4894347 1554653 2168043 1080342 1602223 2450006 3091097 1460326 2451693 2865219 3506489 6932956 1950671 4929972 2085506 1973389 1717993 3098400 3116772 2577965 2890937 0 7761812 6355490 5477483 3527521 6193099 0 7671511 0 0 0 4930829 5442537 6745014 0 0 10423074 2855428 9958272 7399290 7776248 11180232 3690174 5628776 8837740 7656108 9499662 3174303 6257498 7921456 7035192 7521783 7651571 0 5042005 0 7332558 0 0 5910876 3288017 3088780 3995864 3324421 3926606 2667540 3257060 4442070 2694055 4083803 4129693 0 2769046 3433370 6002239 3554869 2744132 3965964 2902447 4228500 2755095 4916099 2455846 2270116 0 4397192 16247287 4371670 5344667 3741243 3905691 2088372 2507778 2821249 2797242 3935262 16962839 16446246 18862591 23998688 5812402 13394008 23328272 16372418 13382984 21910766 19455688 16892576 11647721 22526596 17468010 11204927 17588432 3163582 14192100 9598468 20960268 15506876 5158908 12900593 12890410 20729891 17839827 5728977 26013575 9096237 14647186 24857181 26338298 15645271 10721664 15486298 10772792 13811622 +AAEVAYTGTQEPVKEMQK MGYG000001345_00049 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides xylanisolvens|m__MGYG000001345 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_00049 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00812:aspB; aspartate aminotransferase [EC:2.6.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1909217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVC(Carbamidomethyl)LELL(Xle->Met)TK MGYG000000074_02401 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 - 1.0 ko:K03522 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02401 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339170 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 784677 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVDEDERFPR MGYG000000223_02387 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,3VQ5H@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_02387 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 809425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVDEEERFPIETVK MGYG000002485_00623 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG1960@1|root,COG1960@2|Bacteria,378TZ@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Acyl-CoA dehydrogenase, N-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_00623 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1076367 0 0 1172422 0 0 0 0 0 0 0 0 0 1374074 0 0 0 0 0 987615 0 1137895 0 0 0 0 0 0 0 0 1128965 0 0 0 0 581625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400724 0 81145 0 0 0 0 0 0 0 0 0 0 0 0 0 327766 +AAEVDEEERFPIETVKK MGYG000002485_00623 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG1960@1|root,COG1960@2|Bacteria,378TZ@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Acyl-CoA dehydrogenase, N-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_00623 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1033748 0 0 2018970 1288112 0 0 2242423 1495548 0 1080809 0 0 1607752 1435029 0 0 0 0 1557550 0 1716657 0 0 306001 0 0 0 0 0 1118980 0 0 0 0 1242543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVDIIPR MGYG000001319_00230;MGYG000000018_00286;MGYG000000171_00630 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,4BY3S@830|Butyrivibrio 0.3333333333333333 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000001319_00230 0.3333333333333333 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 646666 0 0 0 282287 0 0 0 258635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1233980 529519 0 0 0 0 0 0 0 0 1033197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 931033 0 0 3546228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVDLIPR MGYG000002580_00753;MGYG000001698_03459;MGYG000000251_01241;MGYG000000271_00461;MGYG000000171_00630;MGYG000000404_00591;MGYG000000002_01946;MGYG000002517_01665;MGYG000002279_00585;MGYG000001319_00230;MGYG000000217_00285;MGYG000000038_02213;MGYG000002492_01767 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia 0.3076923076923077 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.8461538461538461 MGYG000002580_00753 0.07692307692307693 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 202530 0 0 89988 176760 0 159298 595335 303918 196194 140919 0 0 340309 0 132058 185172 612292 649032 400984 0 0 180449 0 496599 217596 229731 1700152 480065 218097 0 0 0 0 139643 232048 259030 0 238507 0 164384 114195 190384 0 158345 199155 169285 182325 0 0 0 119148 0 191738 147243 1046200 297066 90754 0 0 395120 0 120359 185871 166445 685756 577037 239312 0 0 321179 0 119508 249459 97236 104697 533553 0 1428391 619359 493625 0 411367 434110 666812 555536 609247 0 0 0 563399 645022 352519 377488 0 692975 0 0 481553 0 759551 591289 572800 494541 420923 620868 0 0 966173 0 612553 439582 858798 1138347 1811970 0 585561 2211103 907110 0 1005321 2182542 2082704 1027359 734939 0 0 2277926 2165261 950527 1853060 789415 1991609 1976549 0 0 508335 0 1666745 1588823 2094255 986006 2054824 1759467 0 0 503019 0 1866244 1704372 2359985 600296 350884 0 238945 325529 302200 0 184697 170321 158346 225711 202528 0 0 302435 266197 188125 291928 0 311557 0 0 0 206883 0 238445 180670 269822 219821 233766 149380 0 0 296027 0 221287 348642 268228 123375 +AAEVDLLPR MGYG000004891_01493;MGYG000001319_00230;MGYG000000018_00286;MGYG000000171_00630;MGYG000002141_01157;MGYG000000252_00324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3XZKB@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.8333333333333334 MGYG000004891_01493 0.16666666666666666 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2388477 0 0 0 0 1261983 0 527182 0 0 1606871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053147 0 591105 0 0 416074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1949654 0 0 0 0 3288543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVFGR MGYG000002515_04339;MGYG000002506_04112;MGYG000002323_00588 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3ZJCJ@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 F 1.0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 deoA 1.0 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 1.0 2.4.2.4 1.0 ko:K00758 1.0 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 1.0 - 1.0 R01570,R02484,R08222,R08230 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 1.0 Glycos_trans_3N,Glycos_transf_3,PYNP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_04339 0.3333333333333333 thymidine phosphorylase. pyrimidine phosphorylase. In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.-!-Formerly EC 2.4.2.23. phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Bladder cancer 1.0 K00758:deoA, TYMP; thymidine phosphorylase [EC:2.4.2.4] 1.0 none 1.0 0 0 0 0 0 1923118 0 2250211 0 2169249 0 0 0 0 2444534 0 2100939 0 0 0 2306853 1816615 0 1402331 2096604 0 1547737 0 1620540 0 0 1836816 0 1984750 1646436 1421493 0 0 0 0 0 0 0 0 0 2018762 0 1360425 0 0 0 0 931025 0 4422005 0 0 0 0 0 0 0 1248810 0 2285269 0 0 0 0 1249862 0 1925241 1403668 1905856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3899399 0 0 0 0 4933918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1478790 0 0 0 0 0 0 0 0 0 0 0 0 0 2668579 2303422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 515988 0 0 0 0 0 0 0 475457 0 0 1176164 0 119509 92181 0 0 0 +AAEVFVLC(Carbamidomethyl)VK MGYG000001338_03280 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,3WGVJ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 EK 1.0 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Aminotran_MocR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03280 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 1405150 809428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1059249 506170 0 0 0 0 0 0 855112 416117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1459513 498793 405383 0 0 0 0 437500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 684801 0 0 0 0 0 0 0 0 1614891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 756855 0 0 0 0 0 0 1997623 962935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 745724 1481165 1182986 0 0 0 0 0 +AAEVGILPR MGYG000003291_01172;MGYG000001300_01096 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003291_01172 0.5 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 482441 443945 0 400303 0 0 0 0 0 0 0 0 0 126519 364016 0 1028946 904955 0 356756 0 245229 333228 0 0 0 0 0 194070 0 292574 0 0 0 0 538715 0 253117 262500 0 131215 0 0 0 0 0 0 0 0 0 0 262673 452847 0 172950 0 0 0 0 0 0 0 0 0 0 142983 0 0 0 0 0 0 0 0 0 209419 338292 255954 317120 220488 0 0 0 0 0 0 0 0 0 181171 0 0 0 0 0 0 0 0 292406 0 0 0 0 193977 315248 0 0 0 0 0 0 365916 0 1576233 2161321 1256105 1608555 2193768 0 0 0 0 0 0 0 0 0 1537064 1508168 0 2883197 1616809 0 2111028 0 2052474 1090628 0 0 0 0 1963114 2377036 0 2140609 0 0 0 0 2375775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVGLLPR MGYG000003494_02094;MGYG000000022_00767;MGYG000001300_01096;MGYG000000573_01219;MGYG000000084_01970 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003494_02094 0.2 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2173462 0 0 1346491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2097130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVIDMR MGYG000001302.1_01603 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG2987@1|root,COG2987@2|Bacteria,4NF2P@976|Bacteroidetes,2FNQK@200643|Bacteroidia,22V6X@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate 1.0 hutU 1.0 - 1.0 4.2.1.49 1.0 ko:K01712 1.0 ko00340,ko01100,map00340,map01100 1.0 M00045 1.0 R02914 1.0 RC00804 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Urocanase,Urocanase_C,Urocanase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_01603 1.0 urocanate hydratase. urocanase. - 4-imidazolone-5-propanoate = H2O + trans-urocanate. 1.0 1.0 1.0 1.0 Histidine metabolism|Metabolic pathways 1.0 K01712:hutU, UROC1; urocanate hydratase [EC:4.2.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1230269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVIEFNPALEEN(Deamidated)NR MGYG000002492_00661 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00661 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025734 0 0 0 0 618761 0 0 0 0 1147481 0 0 0 0 491963 0 0 0 0 342910 0 0 701514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378698 0 0 0 0 935012 0 0 0 0 662468 0 0 491565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVIEFNPALEENNR MGYG000002492_00661 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00661 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 591732 0 427193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136849 0 353907 0 0 0 0 0 0 0 0 745604 0 347860 0 0 0 1095432 0 2020442 1366740 2845531 834659 1569538 989461 908343 880362 2235879 1043667 1599953 1050983 902111 1234591 572575 14648268 832128 1300983 840840 599436 6501421 939252 1130427 1033806 1110338 10098925 1045264 797615 1872009 1457424 2302101 1231573 1061686 1266979 991236 2679786 2743425 0 10443857 2145274 3796491 2158993 2591042 2540302 2195332 2059211 3560183 3639866 3547755 2386183 2806518 5183079 2645449 2239985 1977452 2043694 2138106 2641524 4023427 1979866 2344771 3208003 2646761 6784273 1718863 2999099 3367815 2078327 12172003 2787255 2843567 2154728 2693624 13071759 0 0 95420 0 399170 0 0 0 0 0 301534 422746 99737 0 0 268687 0 0 0 0 0 0 0 318031 0 0 0 0 0 195127 359807 0 0 0 0 0 0 0 0 0 1113103 376311 0 0 395956 268454 259687 92467 568138 0 258820 0 756131 732897 358672 322300 95420 0 563739 0 496465 341671 356471 71216 269225 406288 0 304976 0 276680 504584 508437 427204 0 557883 300586 +AAEVIEFNPALEENNRYVEIMDIVK MGYG000002492_00661 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00661 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVIGK MGYG000002105_00879 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__SFJ001|s__SFJ001 sp004555865|m__MGYG000002105 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002105_00879 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2350727 0 0 0 0 0 0 0 2283497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVLQGK MGYG000002517_01687;MGYG000000002_01851 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,25V1D@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01687 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 759914 0 0 783427 0 0 0 601524 699652 0 0 0 0 0 584142 0 491610 0 0 0 0 0 0 0 0 589908 0 0 0 682796 0 0 0 0 0 0 863835 0 618843 0 0 1298346 0 0 0 0 1081590 0 0 0 0 0 841260 0 914577 0 0 0 0 0 0 0 0 791003 0 0 0 996381 0 0 0 0 0 0 1140767 0 513952 0 0 352689 0 0 0 962786 1236193 0 0 0 0 0 519258 0 729371 0 0 0 0 0 0 0 0 397430 0 0 0 1031591 0 0 0 0 0 0 0 0 1680523 0 0 2285862 0 0 0 1307715 1357459 0 0 0 0 0 1843261 0 1483825 0 0 0 0 0 0 0 0 995968 0 0 0 1780367 0 0 0 0 0 0 2189658 0 0 0 0 340681 0 0 0 771177 545178 0 0 0 0 0 0 0 671165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802473 0 +AAEVPEAIR MGYG000004475_01155;MGYG000004276_01056;MGYG000001365_00975;MGYG000003819_01175;MGYG000004784_00619;MGYG000002057_00250;MGYG000002926_00519;MGYG000004831_00863;MGYG000002715_01105;MGYG000000099_02384;MGYG000004769_00455 domain d__Bacteria 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,2N6AV@216572|Oscillospiraceae 0.45454545454545453 186801|Clostridia 0.6363636363636364 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 0.8181818181818182 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004475_01155 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 2314071 0 1872727 0 2435920 2336545 2831360 2372794 2331196 2193823 0 2027647 0 2490382 2064982 0 1921510 2135148 0 2770010 2390315 2263126 1878532 2863092 0 2413305 0 2268067 0 0 2574372 2678377 2120309 2722687 2547904 2226333 2776147 2428811 1948051 0 2189412 0 1867517 2132057 1840156 2754128 2363116 2409254 0 1872543 0 2374448 2307360 0 1993071 1018856 0 1784575 2032423 1589765 1038051 1402851 0 2255118 0 963010 0 0 1510553 2377653 2365175 2280571 2654931 2494023 2536644 1828524 2043691 0 2853393 0 2583771 2609796 2436751 2182327 1867102 2508581 0 255642 0 2383615 1705071 0 2234049 1525724 0 1771216 2074386 2379344 1361770 2540832 0 1798552 0 1222004 0 0 2478193 2008271 2141633 2468740 2290274 2197655 1769342 2198328 2446098 0 2956831 0 2221864 3273954 2946285 3473948 2514128 2637570 0 2100675 0 2254412 2432573 0 2192340 3136796 0 2119840 2022689 2607500 2495332 2880355 0 2447562 0 2851856 0 0 3139388 2602472 3052669 3057023 3370468 2706335 2420339 2889235 2141146 0 2154764 0 2154094 2413526 1844416 2712041 2282861 2749236 0 1894435 0 2250452 1994682 0 2101311 1715749 0 2004733 1598800 2581381 1644214 2070616 0 3342147 0 1766245 0 0 2685088 2477337 1765692 2081944 2222866 1905444 1840690 2306772 +AAEVPEAIRK MGYG000003819_01175;MGYG000004784_00619;MGYG000000591_02137;MGYG000004736_00682;MGYG000004769_00455;MGYG000002777_00372;MGYG000004276_01056;MGYG000002659_00440;MGYG000003770_01010;MGYG000004196_00621;MGYG000001617_01231;MGYG000002926_00519;MGYG000000099_02384;MGYG000002715_01105;MGYG000001444_01653;MGYG000001500_00899;MGYG000001365_00975;MGYG000001367_00366;MGYG000004475_01155;MGYG000001356_01784;MGYG000002882_01847;MGYG000002953_00608;MGYG000003869_00064;MGYG000002057_00250;MGYG000004831_00863 domain d__Bacteria 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,2690F@186813|unclassified Clostridiales 0.28 186801|Clostridia 0.6 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 0.84 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003819_01175 0.04 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 2299130 1628571 1726768 1764404 1412756 2172535 2361524 2218866 2235670 1919281 1560518 1437089 1421968 2285777 2055853 1645499 1425180 1425933 1614878 2011353 2374303 1684280 1278276 2339590 1899108 2148882 2010509 1062642 894662 1634799 1657005 1523651 1679650 2425301 2001292 1975558 2242870 1605973 1950088 1260483 1558389 1428474 1482966 1334267 1323250 1991671 1854024 1773013 1569019 1242492 1330573 1668492 1813515 1194654 1627289 396980 1480138 1492769 1515164 1346306 436853 1001686 1558760 1493488 1610853 513516 1614124 1551952 1119431 1162731 1573120 1737026 1194035 1777496 1607892 1436129 2159731 2209248 2851158 2547250 2109685 2160424 2729052 3063376 2793291 2651917 2254388 1691119 1861122 2689467 2836449 1904519 2686039 1156746 2434541 2697376 2664971 2058516 1035638 2561427 2414942 2415509 2328351 1107020 2572086 2259665 2118857 1891951 1843589 2445903 1621459 2567110 2664915 2054005 2167337 2050535 2329874 1683033 1994033 2234285 2127917 2275289 1915825 2554911 1685253 1802815 1658283 2116813 2162774 1595930 2089558 1725312 1836794 1975294 1527415 1659753 1210031 2031179 1796831 2052719 1775986 1508096 2738281 1811241 1867421 2148380 2562066 2582722 2854912 2781557 2506311 2699911 1429438 1220748 1478255 0 1603286 1865009 1754941 1669726 1561791 1406875 1275062 1255462 1286500 842009 1429347 1345102 1480687 1416444 1219450 1389004 1174113 1732264 1072989 1322380 1596446 1967663 1189073 1084283 1029065 1219070 1364458 1273190 1304563 1369335 1218721 1912748 1483924 667291 +AAEVQDGKITVN(Deamidated)GK MGYG000002492_00430 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,25UXG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00430 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 201427 0 0 0 0 229159 128436 103107 0 0 342183 0 73984 0 139289 0 0 0 0 0 0 0 185447 0 0 0 0 97750 0 333816 0 0 0 0 0 0 336332 0 1281361 0 0 0 0 422196 1330203 304024 871070 0 317620 412808 281446 0 155905 0 0 0 0 0 0 0 465380 0 0 0 433619 427971 603966 479422 0 0 0 692406 0 0 774097 0 828989 0 0 0 0 911920 977559 1324582 1851094 0 756467 1286478 883763 0 785425 0 0 0 0 0 0 0 962220 0 0 0 932816 956833 572736 1008293 0 0 0 557046 0 0 228007 0 242941 0 0 0 0 206761 303627 336890 0 0 243455 287783 261155 0 260887 0 0 0 0 0 0 0 258804 0 0 0 0 0 176089 517723 0 0 0 173601 0 0 0 0 207285 0 0 0 0 242800 0 0 0 0 292490 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309531 0 0 0 0 0 0 0 +AAEVQDGKITVN(Deamidated)GKDYVVR MGYG000002492_00430 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,25UXG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00430 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 347903 0 0 0 0 0 0 0 0 142744 221128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 137651 0 0 0 0 0 0 0 0 687639 0 0 0 191784 0 0 0 0 0 168037 0 0 0 0 0 304481 0 0 0 93619 336177 0 0 292932 0 0 0 0 1578329 0 0 0 875747 0 1163476 0 0 1366666 3008043 2866000 865477 1052056 1760704 0 0 916636 1414529 1020314 1249472 0 403543 0 0 1505332 0 0 0 2027707 1877777 0 1186142 1094406 0 0 0 0 0 0 0 0 292936 0 146941 0 0 0 382469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222399 0 337476 487284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVQDGKITVNGK MGYG000002492_00430 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,25UXG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00430 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1371371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 482888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVQDGKITVNGKDYVVR MGYG000002492_00430 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,25UXG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 mglB 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00430 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736498 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVS(Deoxy[S](Ser->Ala)LVGTEK MGYG000000201_01077 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066145|m__MGYG000000201 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_01077 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2266125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3909396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16068368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVSEPATTETPAEEIVSEKPVEPVQK MGYG000001346_03509 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,4AKEY@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_03509 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 685452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 229512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVSLVGTEK MGYG000000201_01077 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066145|m__MGYG000000201 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_01077 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 331094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178262 0 1349597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 693019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380443 0 886388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 738817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 584514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 638328 0 510982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1699651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1531685 0 872916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEVTLVGTEK MGYG000000249_01483;MGYG000004799_00497;MGYG000000268_01898;MGYG000000127_01922 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_01483 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1921446 1678116 1964606 1869886 1889936 0 0 1887455 1414787 1838995 2047891 0 2127696 1693844 1615013 1708160 2593188 0 1887356 0 4552267 0 1454436 0 1757189 1599069 1608983 1635090 0 0 0 1730589 2040704 2209595 1863595 0 1785341 1797936 10148116 5757080 6033940 7289290 8033915 0 0 6941689 8307852 3569740 4550835 0 3042822 6401097 6916558 2243464 20935100 8259546 5675174 0 7579854 0 6167065 0 6600427 8095281 7524045 6780824 0 7079063 0 5643792 6276397 7680232 10765272 0 9514242 8703476 4474486 2986795 4137231 4277043 4797063 0 0 4330271 0 5284799 4053234 0 2874460 4093167 4338072 0 3627672 9282383 4084872 0 3541226 0 9427356 0 4023672 4486320 4277717 6520464 0 2371215 0 4421213 3096015 4441184 3137762 0 4258093 3902706 1983030 2462623 2367536 2545521 2139071 0 0 1857973 1960493 2506869 2104005 0 2586686 1986893 1774038 1693484 7714646 2977167 1257082 0 3619437 0 3528317 0 1912835 1668875 2091264 4567060 0 3164427 0 1810049 3025570 2149309 1953670 0 1743196 2381553 913993 264465 802516 1332276 0 0 0 996416 711621 463147 0 0 686742 668555 0 624601 3994830 0 0 0 721676 0 0 0 680262 442822 0 2756294 0 982533 0 683224 696419 817964 665355 0 0 403633 +AAEVVGK MGYG000002545_01217;MGYG000002274_02693;MGYG000000022_02788;MGYG000003899_02226;MGYG000002224_02000;MGYG000003166_00833;MGYG000003921_00033;MGYG000001300_02837;MGYG000001255_00900;MGYG000002040_00906;MGYG000000039_02141 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002545_01217 0.09090909090909091 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 246105 1041285 171428 425477 235115 58195 40206 0 0 347540 0 0 150294 621323 556221 0 163585 478829 293578 0 273084 132793 382453 273123 271996 328016 290486 261546 0 0 1293607 0 444080 0 172886 100910 268340 483042 1049829 189624 57098 206613 689939 1393227 707904 0 0 399768 0 0 928773 1034387 542831 0 1419710 589703 970740 407771 801223 1419885 1509614 1022911 856991 604954 706705 608922 0 0 1151083 0 617542 0 703867 494393 421762 451717 386095 220828 58327 343068 148723 140435 223248 0 0 256149 0 0 403527 122662 163115 0 595362 0 209206 231502 262466 284044 250479 867678 381933 799933 180906 87250 0 0 238548 0 338570 0 350215 311147 159700 291038 490233 488280 321671 72505 122117 0 1804797 0 0 125474 0 0 1221150 438018 212731 0 447861 335107 614927 620634 1248753 223066 966391 403237 483512 555927 564721 2149409 0 0 350490 0 505686 0 872844 738715 541837 257447 526133 1393113 145695 140515 73951 71117 240335 0 0 90554 0 0 59448 295078 229416 0 867568 174034 87051 228941 152852 350110 82589 110710 127748 218536 407487 1346459 0 0 60164 0 466764 0 332052 277502 140929 35554 +AAEVWANIEENKR MGYG000000099_00313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0539@1|root,COG0761@1|root,COG0539@2|Bacteria,COG0761@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,268MU@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis 1.0 ispH 1.0 - 1.0 1.17.7.4 1.0 ko:K02945,ko:K03527 1.0 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 1.0 M00096,M00178 1.0 R05884,R08210 1.0 RC01137,RC01487 1.0 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin,LYTB,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_00313 1.0 4-hydroxy-3-methylbut-2-enyl diphosphate reductase. HMBPP reductase. Forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase.-!-This is the last enzyme in the non-mevalonate pathway for isoprenoid biosynthesis.-!-This pathway, also known as the 1-deoxy-D-xylulose 5-phosphate (DOXP) or as the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts.-!-The enzyme acts in the reverse direction, producing a 5:1 mixture of isopentenyl diphosphate and prenyl diphosphate.-!-Formerly EC 1.17.1.2. (1) H2O + isopentenyl diphosphate + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. (2) dimethylallyl diphosphate + H2O + 2 oxidized [2Fe-2S]-[ferredoxin] = (2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + 2 H(+) + 2 reduced [2Fe- 2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Ribosome 1.0 K02945:RP-S1, rpsA; small subunit ribosomal protein S1|K03527:ispH, lytB; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4] 1.0 none 1.0 0 0 0 0 0 0 0 225429 0 118082 0 0 0 0 485017 0 0 0 0 0 0 0 0 0 0 0 0 0 87874 0 0 0 0 0 0 110058 0 0 0 0 0 0 0 0 0 866781 0 820444 0 0 0 0 993677 0 0 0 0 637858 0 0 0 0 0 0 0 0 626252 0 0 0 0 727184 0 644980 0 0 0 0 0 0 0 0 0 277388 0 202724 0 0 0 0 180357 0 0 0 0 255014 0 0 0 0 0 0 0 0 0 0 0 0 0 278213 0 0 0 0 0 0 0 0 0 0 0 99252 0 614561 0 0 0 0 644625 0 0 0 0 0 0 0 0 0 0 0 0 0 306122 0 0 0 0 219535 0 250509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114573 0 0 0 0 0 0 91589 0 0 +AAEWGATEQNQATVGR MGYG000002478_01138 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG3883@1|root,COG1196@2|Bacteria,COG3883@2|Bacteria,4P07U@976|Bacteroidetes,2FN9Y@200643|Bacteroidia,4APBT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 nuclear chromosome segregation 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Collagen,DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01138 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 349087 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEWLNAYTTAK MGYG000001338_03290 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3Y1DY@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K02058 1.0 - 1.0 M00221 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 3.A.1.2 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03290 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02058:ABC.SS.S; simple sugar transport system substrate-binding protein 1.0 none 1.0 0 0 1159094 0 0 407786 169584 650038 0 0 2144843 679636 0 198797 0 429566 0 0 0 0 0 382069 0 204127 0 0 0 0 0 0 0 0 328780 0 0 0 0 349435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291618 0 279791 0 0 0 0 0 0 0 0 262562 0 0 0 0 0 0 0 0 0 0 0 331718 142774 0 0 0 0 0 149425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 851436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 626084 0 0 432886 789613 555592 0 0 943236 847272 0 788885 0 798056 0 0 0 0 0 544466 0 653388 0 0 0 0 0 0 0 0 963603 0 0 0 0 637142 +AAEYAALQSSAVAAAK MGYG000004735_00145 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00145 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1307692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEYAALQSSAVAAAKR MGYG000004735_00145 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00145 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1200529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEYAGGDPAK MGYG000002438_00932 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,22WE8@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00932 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03072:secD; preprotein translocase subunit SecD|K12257:secDF; SecD/SecF fusion protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEYAR MGYG000003279_01589;MGYG000000003_01532;MGYG000001346_03588;MGYG000000003_02653;MGYG000002753_00262 domain d__Bacteria 1.0 COG0702@1|root,COG0702@2|Bacteria,4PNS2@976|Bacteroidetes,2G0WT@200643|Bacteroidia 0.4 976|Bacteroidetes 0.8 GM 0.4 Pfam:SusD 0.4 - 1.0 - 1.0 - 1.0 ko:K21572 0.6 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 0.6 8.A.46.1,8.A.46.3 0.6 - 1.0 - 1.0 SusD-like_3,SusD_RagB 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003279_01589 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 0.6 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1354180 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 971500 0 0 0 936508 0 0 1028215 0 0 1056771 0 0 1472341 1277022 813656 0 0 0 1267082 0 0 0 0 0 0 0 0 1574365 0 0 0 0 0 0 0 0 54060 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234068 0 0 0 0 0 0 0 1379544 0 1729319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEYATLQNNVTSAAR MGYG000000251_00721 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter saccharivorans|m__MGYG000000251 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3XZR6@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Acetyl-CoA carboxylase alpha subunit 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_00721 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 842271 0 0 0 0 0 570273 0 0 0 0 410221 0 0 0 0 534691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1071898 0 0 0 0 0 552962 0 0 0 0 210987 0 0 0 0 179608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392547 0 0 0 0 513270 0 0 0 0 678907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265464 0 0 0 0 484131 0 0 0 0 537973 0 0 0 0 0 0 0 0 0 0 +AAEYDKNTR MGYG000001292_00824 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG1566@1|root,COG1566@2|Bacteria,2I2G9@201174|Actinobacteria,4CZ5W@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 V 1.0 DivIVA protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DivIVA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001292_00824 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 41141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEYIYNAYK MGYG000001496_03152;MGYG000001954_02140;MGYG000001619_01035;MGYG000001607_02072;MGYG000000179_02579;MGYG000001367_03149;MGYG000000146_01010;MGYG000003355_03067;MGYG000000909_01807;MGYG000004087_01471;MGYG000003822_00610;MGYG000000198_05065;MGYG000000133_00993;MGYG000000301_01128 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,2686V@186813|unclassified Clostridiales 0.42857142857142855 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 0.7142857142857143 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001496_03152 0.07142857142857142 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 374652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 767088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739790 0 0 0 0 +AAEYLEEPIDR MGYG000003937_01664 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01664 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1005799 0 0 0 0 898154 0 0 0 0 1207795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 356288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEYLEEPIDRLK MGYG000003937_01664 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01664 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 717057 0 0 0 0 0 0 0 1489787 0 0 0 0 0 0 0 1489267 0 0 0 0 894021 0 0 0 0 1197097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245018 0 0 0 0 0 0 0 0 0 194560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128428 0 0 0 0 0 0 0 271663 0 0 0 0 0 0 0 0 0 375235 0 0 0 0 0 0 0 0 0 0 0 225142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEYLEEPIER MGYG000002545_01147;MGYG000002040_00963;MGYG000000195_02140;MGYG000001300_02904;MGYG000001627_01221;MGYG000002274_00855;MGYG000002651_01056;MGYG000003921_01150;MGYG000002619_01707;MGYG000000022_02047;MGYG000003899_00603 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002545_01147 0.09090909090909091 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 1898984 2096936 2583105 2316659 693426 1902508 1966994 1559583 2263091 2093798 2359977 1816689 2037615 2062783 1528468 2130575 2402891 7274087 2217778 2286607 1668755 2226267 6001293 2000907 2208100 2102613 1818189 6607310 1953498 1935278 2134984 1701079 2311502 2352602 1884989 1993559 2369673 2563758 2243354 1578423 2013751 1874188 1454602 1700256 2146142 1411641 2307015 1273938 1641424 1532066 1702111 2133956 1892293 1584452 2040295 7553698 2424019 2149373 483746 1613767 8550944 1800131 2431697 1947030 2082956 7448246 965285 1818781 1898118 1637427 1796815 2255995 1369664 2099789 2097236 1835049 1472493 1695535 2129035 2204781 2690069 2289165 2679065 1679066 2567316 1920287 2418740 2573153 2050670 2337650 1733165 1817606 2103520 7634636 1292020 1686935 2119686 2096079 7705101 992123 2096033 1860745 1499169 9064174 2126879 2297477 2712285 1768123 1825797 2090039 1919814 2218645 2130537 2498606 1679937 2362364 2957085 2196334 2371151 2990089 3106684 2233625 2513734 2630319 2722022 2940201 2728531 2099904 2428258 2285725 2371127 8328895 2763982 2258142 2491565 3562333 7134083 2707743 2387637 2128501 2165439 9367521 1745709 2443127 3197168 2037272 2797722 2587584 1469784 2313629 2081486 2845982 501388 836851 1160466 885421 734950 780374 1003091 1023396 847229 1015607 859661 362847 883728 874419 0 870068 890210 4538288 530288 781645 767814 751144 6976970 1083828 0 579648 815350 8009216 645560 764147 817208 717652 1073898 938495 762244 417578 840430 1151427 +AAEYLEEPIERLK MGYG000000022_02047;MGYG000003899_00603 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_02047 0.5 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAEYPIHYDWGK MGYG000000278_00219 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA3402|s__UBA3402 sp003478355|m__MGYG000000278 1.0 COG2222@1|root,COG2222@2|Bacteria,1TRTA@1239|Firmicutes,24BGB@186801|Clostridia,21ZI4@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 M 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 ko:K10708 1.0 - 1.0 - 1.0 R08125 1.0 RC00053,RC01805 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 SIS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000278_00219 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K10708:frlB; fructoselysine 6-phosphate deglycase [EC:3.5.-.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71074 0 0 0 0 103426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1874117 0 0 0 0 1914678 0 0 0 0 1802907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994301 0 0 0 0 988314 0 0 0 0 978446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 319946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114527 0 0 0 0 0 0 0 0 0 0 +AAEYSGSEDAWK MGYG000000243_02605 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 MGYG000000243_02605 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1429500 1971028 3755417 1667307 2448347 1391534 2110123 1386610 0 0 0 0 1576853 1591435 0 1497698 1276356 647891 1296437 1248700 0 928807 1271875 1811804 0 1508634 0 1064807 1249512 1644043 4395356 1609761 4516016 1935335 1538035 0 1527856 3411809 820723 0 353013 0 963495 0 0 0 0 0 0 0 602601 712831 0 650403 127602 0 382016 0 0 0 324579 0 0 733124 0 563312 0 661062 534952 0 393626 607030 646379 0 682935 955799 892446 0 707766 413933 647296 0 854415 468489 0 0 0 0 592023 482635 0 957232 1033184 0 724413 777673 0 0 0 0 0 765907 0 351139 347014 429990 716937 413055 771281 195116 545884 0 1133004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAF(Phe->Asp)GVILITTK MGYG000002171_02947;MGYG000000243_00119 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_02947 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1207250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAF(Phe->Asp)GVVLITTK MGYG000000236_00639;MGYG000003693_02994;MGYG000001780_03070;MGYG000001313_00646;MGYG000002171_00975;MGYG000000243_01524;MGYG000001787_00483;MGYG000003681_02851;MGYG000001364_00903;MGYG000000243_02728;MGYG000000138_01891 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.9090909090909091 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6363636363636364 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_00639 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 901434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAF(Phe->Gly)GVILVTTK MGYG000000042_02037;MGYG000002478_01844;MGYG000001415_00852;MGYG000002478_00434;MGYG000001337_00976;MGYG000001337_04109;MGYG000002203_01364;MGYG000000003_01805;MGYG000003279_01059;MGYG000000236_03728;MGYG000000273_01279;MGYG000003363_02700;MGYG000004756_00447;MGYG000000236_01449 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.7857142857142857 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec 0.5714285714285714 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_02037 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1097423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFA(Ala->Asp)KFMETK MGYG000000262_01692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000262_01692 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1412437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1391091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 650139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFAEAK MGYG000004735_02771 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,25VDM@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Transketolase, thiamine diphosphate binding domain protein 1.0 tktA 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Hydrolase_3,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_02771 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 575284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2642581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFAEAR MGYG000002517_02816 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Transketolase, thiamine diphosphate binding domain 1.0 tktA 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Hydrolase_3,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02816 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFAPPLDGAGNSVK MGYG000000003_01141;MGYG000000196_02443 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2066@1|root,COG2066@2|Bacteria,4NERJ@976|Bacteroidetes,2FM3D@200643|Bacteroidia 0.5 976|Bacteroidetes 1.0 E 1.0 Belongs to the glutaminase family 1.0 glsA 1.0 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.0 3.5.1.2 1.0 ko:K01425 1.0 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 1.0 - 1.0 R00256,R01579 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glutaminase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_01141 0.5 glutaminase. L-glutamine amidohydrolase. - H2O + L-glutamine = L-glutamate + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Metabolic pathways|Glutamatergic synapse|GABAergic synapse|Proximal tubule bicarbonate reclamation|MicroRNAs in cancer|Central carbon metabolism in cancer 1.0 K01425:glsA, GLS; glutaminase [EC:3.5.1.2] 1.0 none 1.0 3099408 0 0 0 0 0 3244903 0 3747856 0 0 0 0 3285891 0 0 0 0 4020864 2667976 2768257 0 0 0 0 2850568 2291718 0 2376218 0 0 0 0 0 0 3211474 2559239 0 0 0 0 0 0 0 0 0 470502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182403 0 0 258203 0 0 0 0 0 309636 0 415368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFAWK MGYG000001056_00630;MGYG000002293_02867;MGYG000002960_00779 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 susC 1.0 - 1.0 - 1.0 ko:K21573 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14.6.1 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001056_00630 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21573:susC; TonB-dependent starch-binding outer membrane protein SusC 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573651 0 0 0 0 1102375 0 0 0 0 1111266 0 0 2070799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1163470 0 0 0 0 998713 0 0 0 0 834806 0 0 884543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1078630 0 0 0 0 917645 0 0 0 0 919201 0 0 291771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2248226 0 0 0 0 2062858 0 0 0 0 1346722 0 0 0 0 0 0 0 0 0 0 +AAFDAADLPFDLHR MGYG000000022_00086 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3WGWD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 malonyl CoA-acyl carrier protein transacylase 1.0 fabD 1.0 - 1.0 2.3.1.39 1.0 ko:K00645 1.0 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 1.0 M00082 1.0 R01626,R11671 1.0 RC00004,RC00039,RC02727 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 Acyl_transf_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00086 1.0 [acyl-carrier-protein] S-malonyltransferase. MCAT. Essential, along with EC 2.3.1.38, for the initiation of fatty-acid biosynthesis in bacteria.-!-Also provides the malonyl groups for polyketide biosynthesis.-!-The product of the reaction, malonyl-ACP, is an elongation substrate in fatty-acid biosynthesis.-!-In Mycobacterium tuberculosis, holo-ACP (the product of EC 2.7.8.7) is the preferred substrate.-!-This enzyme also forms part of the multienzyme complexes EC 4.1.1.88 and EC 4.1.1.89.-!-Malonylation of ACP is immediately followed by decarboxylation within the malonate-decarboxylase complex to yield acetyl-ACP, the catalytically active species of the decarboxylase.-!-In the enzyme from Klebsiella pneumoniae, methylmalonyl-CoA can also act as a substrate but acetyl-CoA cannot whereas the enzyme from Pseudomonas putida can use both as substrates.-!-The ACP subunit found in fatty-acid biosynthesis contains a pantetheine-4'-phosphate cofactor; that from malonate decarboxylase also contains pantetheine-4'-phosphate but in the form of a 2'-(5-triphosphoribosyl)-3'-dephospho-CoA cofactor. holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis|Prodigiosin biosynthesis|Metabolic pathways|Fatty acid metabolism 1.0 K00645:fabD, MCAT, MCT1; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71360 0 0 0 0 66149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124403 0 0 0 0 77981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158487 0 0 0 0 206937 0 0 0 0 131746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408761 0 0 0 0 390460 0 0 0 0 429668 0 0 0 0 0 0 0 0 0 0 +AAFDDAIAAR MGYG000002494_02707;MGYG000002534_04377;MGYG000003372_02551 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,3WVEI@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 O 1.0 HflC and HflK could encode or regulate a protease 1.0 hflK 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 1.0 - 1.0 ko:K04088 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Band_7,HflK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02707 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04088:hflK; modulator of FtsH protease HflK 1.0 none 1.0 0 0 443098 0 0 1059852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 872958 0 928725 0 0 0 0 0 703039 0 0 200602 0 0 0 0 0 0 0 1233999 0 0 2202456 0 0 0 0 0 0 0 0 0 0 1851512 0 0 0 0 2420253 0 2374529 0 0 0 0 0 1794882 0 0 2058537 0 0 0 0 1257723 0 0 330437 0 0 510106 0 0 0 0 0 0 0 0 0 0 223298 0 0 0 0 1015748 0 540818 0 0 0 0 0 620343 0 0 0 0 0 0 0 371284 0 0 908677 0 0 871532 0 0 0 0 0 0 0 0 0 0 364791 0 0 0 0 956188 0 0 0 0 0 0 0 619989 0 0 341045 0 0 0 0 611233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464847 0 0 0 0 0 0 0 0 +AAFDEAK MGYG000001338_02856;MGYG000002298_02139 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 tktA 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Hydrolase_3,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02856 0.5 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 2107047 1767422 0 0 1367521 0 0 0 2071561 0 1914332 2653085 1840094 2985795 0 0 1796229 2470549 2236219 2419956 2267696 1634065 515779 2456042 0 1643325 1667931 3876339 2225308 0 1991905 845212 0 2304981 1499481 0 1238255 0 1991289 0 0 0 0 0 0 0 1013458 0 479687 243380 0 224956 0 0 722512 0 183916 314333 181688 0 375022 278975 0 321594 0 1391220 395995 0 522493 0 0 0 0 0 561445 0 1370022 376073 0 0 651035 0 0 0 744622 0 385376 484810 644079 585706 0 0 64045 770870 790121 611100 795938 0 318490 635779 0 666735 314085 821799 564441 0 1491780 816849 0 563168 184206 0 439350 0 1124723 1066849 0 0 0 0 0 0 433392 0 112950 654909 135566 404132 0 0 527320 490056 329044 109677 1374006 139474 1235578 188940 0 451845 572948 3879869 726709 0 912113 980233 0 135587 152233 0 1191668 0 1547300 0 0 0 629579 0 0 0 604580 0 377475 544566 129819 209010 0 0 115149 96330 267797 400249 211159 428761 1023442 110120 0 530852 400318 726387 255441 0 1394893 2343612 0 522612 456655 0 950710 +AAFDEAR MGYG000004869_02367;MGYG000001642_01428;MGYG000000133_02556 domain d__Bacteria 1.0 COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia 0.6666666666666666 186801|Clostridia 0.6666666666666666 G 0.6666666666666666 Psort location Cytoplasmic, score 8.87 0.6666666666666666 tktA 0.6666666666666666 - 1.0 2.2.1.1 0.6666666666666666 ko:K00615 0.6666666666666666 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 0.6666666666666666 M00004,M00007,M00165,M00167 0.6666666666666666 R01067,R01641,R01830,R06590 0.6666666666666666 RC00032,RC00226,RC00571,RC01560 0.6666666666666666 ko00000,ko00001,ko00002,ko01000 0.6666666666666666 - 1.0 - 1.0 - 1.0 Hydrolase_3,Transketolase_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004869_02367 0.3333333333333333 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6666666666666666 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 0.6666666666666666 none 1.0 237510 0 0 0 0 0 0 0 0 97003 377549 570653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102242 0 0 0 0 0 0 0 0 0 0 0 253503 0 0 0 223824 0 0 76520 539664 398564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502841 0 0 0 747553 0 65301 0 0 208611 0 0 782968 0 443114 944011 0 518563 402894 0 343692 957804 655787 490208 232646 447391 810595 919715 753036 0 886211 0 623326 1238119 0 420060 817642 708259 812502 0 633369 0 485068 676955 830198 725845 0 469847 841083 695612 0 0 0 0 0 0 0 0 0 0 0 0 133805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152097 2784984 0 1980369 3308257 0 828918 2889369 0 1393679 3419738 3220530 2766565 1916328 6426991 3275261 1550194 2080940 0 2236414 0 4160896 1748834 0 1480583 2692595 2447370 3411252 0 3027299 0 1546565 2358424 4675252 2542153 0 3980803 1892837 1615342 +AAFDEAR(Arg->Lys) MGYG000004869_02367;MGYG000001642_01428;MGYG000000133_02556 domain d__Bacteria 1.0 COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia 0.6666666666666666 186801|Clostridia 0.6666666666666666 G 0.6666666666666666 Psort location Cytoplasmic, score 8.87 0.6666666666666666 tktA 0.6666666666666666 - 1.0 2.2.1.1 0.6666666666666666 ko:K00615 0.6666666666666666 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 0.6666666666666666 M00004,M00007,M00165,M00167 0.6666666666666666 R01067,R01641,R01830,R06590 0.6666666666666666 RC00032,RC00226,RC00571,RC01560 0.6666666666666666 ko00000,ko00001,ko00002,ko01000 0.6666666666666666 - 1.0 - 1.0 - 1.0 Hydrolase_3,Transketolase_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004869_02367 0.3333333333333333 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6666666666666666 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 2348079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1687940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 812362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732846 0 0 0 0 0 +AAFDEFM(Oxidation)ATK MGYG000002040_01920;MGYG000002545_01451 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002040_01920 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1497359 0 0 0 0 352885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546382 0 0 0 0 687596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317734 0 0 0 0 390366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355880 0 0 0 0 331687 0 0 0 0 146198 0 0 0 0 0 0 0 0 0 0 +AAFDEFMATK MGYG000002040_01920;MGYG000002545_01451 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002040_01920 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 1674143 1984022 2340740 2025239 1761549 2083810 2192008 0 2466491 0 0 0 1928344 0 1582461 1948606 2083427 6015745 0 1899297 1539653 1805739 6785808 1899298 1952794 2305176 2198931 7318055 0 0 2941544 1939811 1867783 0 0 1973654 1741589 2125598 350133 229811 615122 337691 470749 330492 424898 0 316791 0 0 0 451628 0 300607 502772 358266 7334507 0 283896 0 457186 9634420 397310 451243 389823 529499 7627547 0 0 412105 381542 592656 0 0 264485 380954 623070 921578 898938 1026725 1061474 1419100 1560942 1244225 0 1368938 0 0 0 1209392 0 853946 1149683 1320956 7072776 0 658237 835768 983361 6601838 1400039 915872 1020293 899558 7145239 0 0 1432680 1214301 703290 0 0 1269163 1142475 1175743 568614 276627 684377 475993 602701 603466 504509 0 489820 0 0 0 565618 0 488859 685363 552935 2965901 0 377095 581110 578964 3060521 643390 719356 429396 524129 2573361 0 0 644287 628558 599073 0 0 469696 658552 556893 0 0 181591 0 100959 185935 120347 0 166202 0 0 0 159628 0 0 251948 0 3357474 0 0 0 99134 3019474 166433 159628 167574 0 3174598 0 0 92578 0 129321 0 0 0 175356 107464 +AAFDFAVEHQSVER MGYG000002506_03405;MGYG000002477_00657;MGYG000002494_02407;MGYG000002323_04218;MGYG000002515_03906 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0056@1|root,KOG1353@2759|Eukaryota,38ERH@33154|Opisthokonta,3BCEE@33208|Metazoa,3CU79@33213|Bilateria,40ASR@6231|Nematoda,1KTUU@119089|Chromadorea,40X9Y@6236|Rhabditida 1.0 33208|Metazoa 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane 1.0 ATP5A1 1.0 - 1.0 - 1.0 ko:K02132 1.0 ko00190,ko01100,ko04714,ko05010,ko05012,ko05016,map00190,map01100,map04714,map05010,map05012,map05016 1.0 M00158 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_A,ATP-synt_B,ATP-synt_C,ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,GidB,OSCP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_03405 0.2 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways|Thermogenesis|Alzheimer disease|Parkinson disease|Huntington disease 1.0 K02132:ATPeF1A, ATP5A1, ATP1; F-type H+-transporting ATPase subunit alpha 1.0 none 1.0 0 456022 479396 0 0 586371 0 0 0 418207 0 0 0 0 0 0 0 0 493797 347593 0 571446 0 918806 280544 0 0 0 506196 0 0 0 567622 0 0 0 0 288748 0 1347155 1217272 0 1285422 1984204 0 0 0 1379409 0 0 0 0 0 0 0 0 1509251 919698 1688411 3400760 0 2581221 1586235 0 0 0 1654179 0 0 0 1317053 0 0 0 0 1339580 0 478717 427171 0 423292 950338 0 0 0 478479 0 0 0 0 0 0 0 0 419976 451746 460536 584477 0 982015 259371 0 0 0 457446 0 0 0 481467 0 0 0 0 458203 0 434963 532618 0 324619 730021 0 0 0 599031 0 0 0 0 0 0 0 0 442084 312231 232809 870416 0 733861 555712 0 0 0 327029 0 0 0 642445 0 0 0 0 323553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308458 0 0 0 0 0 0 0 0 0 +AAFDFLYASTK MGYG000003693_02097 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 29RCG@1|root,30CEM@2|Bacteria,4PHRC@976|Bacteroidetes,2FNH2@200643|Bacteroidia,4APWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Fimbrillin-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Mfa_like_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_02097 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479445 0 0 0 0 1152733 0 0 0 0 620347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFDGTDFEIMETQYGEGDAAK MGYG000000201_01306;MGYG000000002_00716 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ95@1239|Firmicutes,24AX7@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 PFAM periplasmic binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_01306 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 804155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFDHNYAK MGYG000001789_01365 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002161565|m__MGYG000001789 1.0 COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,2FMB3@200643|Bacteroidia,4AKGW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Inositol-3-phosphate synthase 1.0 ino1 1.0 - 1.0 5.5.1.4 1.0 ko:K01858 1.0 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 1.0 - 1.0 R07324 1.0 RC01804 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Inos-1-P_synth,NAD_binding_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001789_01365 1.0 inositol-3-phosphate synthase. myo-inositol-1-phosphate synthase. The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the -CHO at C-1; finally, the enzyme-bound NADH reconverts C-5 into the -CHOH- form. D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. 1.0 1.0 1.0 1.0 Streptomycin biosynthesis|Inositol phosphate metabolism|Metabolic pathways 1.0 K01858:INO1, ISYNA1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1191577 0 0 0 0 1517928 0 0 0 0 1334306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354496 0 0 0 0 291856 0 0 0 0 302864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80707 0 0 0 0 0 0 0 0 0 81289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 629050 0 0 0 0 554327 0 0 0 0 357730 0 0 0 0 0 0 0 0 0 0 +AAFDHNYASR MGYG000004797_04061;MGYG000000243_01209 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,2FMB3@200643|Bacteroidia,4AKGW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Inositol-3-phosphate synthase 1.0 ino1 1.0 - 1.0 5.5.1.4 1.0 ko:K01858 1.0 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 1.0 - 1.0 R07324 1.0 RC01804 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Inos-1-P_synth,NAD_binding_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_04061 0.5 inositol-3-phosphate synthase. myo-inositol-1-phosphate synthase. The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the -CHO at C-1; finally, the enzyme-bound NADH reconverts C-5 into the -CHOH- form. D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. 1.0 1.0 1.0 1.0 Streptomycin biosynthesis|Inositol phosphate metabolism|Metabolic pathways 1.0 K01858:INO1, ISYNA1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] 1.0 none 1.0 3070043 2856552 5921646 3815990 4248257 3238898 4202764 3066071 3671204 2714830 3264517 2877845 4580672 2752639 2692920 5711838 2851286 2131583 2937517 2949533 2984178 3142848 2866606 4031752 2424348 2778354 2839964 2502998 2738068 3813351 6048935 2785837 6703607 2580401 2944233 2923325 2561636 7411642 2524834 1115317 1539666 1715075 0 1433556 1394560 1899533 2671418 1555646 1867038 1316656 3401675 1601120 2043803 2360722 1481244 1209869 1344313 1117963 1194128 0 2234397 2980957 2655976 1239814 1326378 1699643 1340918 1372815 1055708 1613316 1439542 3224223 0 1712201 1160812 1546543 1448206 1283998 1899630 1534886 2754130 1770516 1742443 1182908 2080979 1718538 1605295 1601544 2822699 1436650 1507105 2330519 1795291 3231934 1581993 1424255 1419849 1180125 2283315 1888050 1580754 1645557 1698120 1782698 1498456 1200244 2207045 1129222 1219158 912043 1198105 1903283 1763103 1661239 283468 94590 438547 161469 225186 242023 361004 341024 280060 470125 333179 271463 446320 278524 275615 297932 228915 724062 300684 283971 266914 177321 84388 206288 342602 358223 298329 0 451686 301509 495229 305985 567389 112535 444585 269740 209707 339415 1334149 1339776 914679 948666 2779512 1347178 1459797 1641129 1301443 677315 957793 920587 3122399 1217006 1026365 2050086 1157227 2872476 1517617 1417882 860033 1546686 3083464 1262687 1786027 1542354 1345373 2468130 1269929 1507595 1131150 980522 1071169 1446151 2550222 1731253 1834206 1227362 +AAFDHNYASRLDGN(Deamidated)NVKDC(Carbamidomethyl)K MGYG000000243_01209 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,2FMB3@200643|Bacteroidia,4AKGW@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Inositol-3-phosphate synthase 1.0 ino1 1.0 - 1.0 5.5.1.4 1.0 ko:K01858 1.0 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 1.0 - 1.0 R07324 1.0 RC01804 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Inos-1-P_synth,NAD_binding_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01209 1.0 inositol-3-phosphate synthase. myo-inositol-1-phosphate synthase. The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the -CHO at C-1; finally, the enzyme-bound NADH reconverts C-5 into the -CHOH- form. D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. 1.0 1.0 1.0 1.0 Streptomycin biosynthesis|Inositol phosphate metabolism|Metabolic pathways 1.0 K01858:INO1, ISYNA1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFDITQLD MGYG000002515_02933;MGYG000002506_02717 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3XNX9@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 K 1.0 transcriptional regulator 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_02933 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1846883 0 0 1965650 1018656 3308227 2604386 3912498 2636016 3723438 0 1644011 0 1872294 2423521 0 1758720 0 2404815 2150558 2668775 5124648 0 6052128 3019459 2508444 0 0 2416416 2847143 0 0 0 3278974 0 2538324 2085993 0 578172 0 0 595697 860373 2316730 766223 1338977 721073 1440003 0 717365 0 943182 993375 0 805161 0 1242534 989934 73624 2757515 0 2343321 913327 900394 0 0 601740 1134939 0 0 0 746269 0 661373 701785 0 1567778 0 0 1043884 940971 1610488 1425731 1720958 768188 1587265 0 1198117 0 1421414 1610441 0 955718 0 1736600 1883127 1245437 2848250 0 2711286 1881117 1688615 0 0 1578133 1538407 0 0 0 1727669 0 962440 1285796 0 2627084 0 0 2177958 1531281 2342934 2232208 2014532 2464365 2528829 0 1798560 0 2322138 2540644 0 1726222 0 2427335 2444832 2891430 1556628 0 2482956 1640791 1885453 0 0 2762456 2254883 0 0 0 83994 0 2600136 2796738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFDKFI(Xle->Met)ETK MGYG000004845_01965 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Monoglobales_A|f__UBA1381|g__UBA4716|s__|m__MGYG000004845 1.0 COG0479@1|root,COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0479@2|Bacteria,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000004845_01965 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3786917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFDKFMETK MGYG000000022_01634 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000022_01634 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 70429 74132 64098 0 122492 75686 0 109469 0 138889 261163 0 70731 83250 0 158359 71040 451544 0 53551 197851 46238 515534 165091 130911 84595 133039 491271 123670 136816 160375 76600 76500 0 109326 0 81023 72215 300379 317411 295111 0 396194 389730 358103 456817 0 473724 812866 0 443996 426146 0 344527 302467 0 0 379058 151783 283723 0 310894 387585 407703 429792 3645661 385746 259139 365550 373428 284054 407946 257752 0 412548 447874 1480107 1410041 1503483 0 1210872 1490840 1500403 1532234 0 1788205 1527055 0 1218042 1765976 0 1433813 1444058 4436905 0 1237782 1251070 1324126 5026059 1682663 1711050 0 1668043 5027503 1488263 1460173 1690850 1556563 1361138 1710069 1736553 0 1751756 1428870 300822 450061 383884 0 382589 296860 343553 328485 0 402480 313798 0 311248 273523 0 177664 521114 1120557 0 201516 257141 306866 1012480 236948 226536 279570 387570 1789655 267388 295961 65594 254608 88346 206817 296560 0 279658 342807 623126 645053 1561291 0 465139 740389 1148275 821394 0 965884 703690 0 903324 745326 0 906883 698638 6596192 0 473721 1015664 867236 8604868 953076 707250 520789 415225 8249060 940761 483557 1213641 914453 1566541 631586 951777 0 534813 1095022 +AAFDKFT(Thr->Met)ETK MGYG000000389_00578 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900550935|m__MGYG000000389 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000389_00578 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1341104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFDKFVETK MGYG000002517_00959;MGYG000000076_02414 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002517_00959 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 904045 251248 232703 947056 297351 538003 392465 782021 596254 1188067 34730 509147 291891 665388 1113247 404115 868685 0 1490947 925968 881396 661341 0 361948 933795 880254 1077619 0 135303 480666 367163 0 98453 745076 601332 736563 752639 108470 98728 131913 0 63060 0 243229 0 0 0 0 305220 0 0 0 111828 51412 91907 0 93046 74749 186032 0 0 0 57826 94458 0 0 0 216950 0 0 0 136552 0 0 67053 0 1321388 165457 49072 961641 182313 299417 797745 875038 837457 650209 469281 683489 516664 939595 1041289 593540 922315 0 1007483 1048098 543698 287534 0 251546 1487955 1451976 1253442 0 331076 1158152 0 0 150364 646128 950798 753434 1732675 86150 5410016 1064694 950898 6004081 2512030 1535527 2580722 6999147 5849934 2667533 1802274 2759194 1656403 7307548 6128338 2340986 3874992 0 3731515 5914659 4001285 376096 0 542373 5757394 5377251 5854047 0 1253432 4319901 1245732 0 1078920 3679936 5666217 4927752 6565893 980352 3952719 3323890 5257266 73556 3343785 4771334 3734094 2987555 4286488 6571688 3642039 3975167 1158856 7740356 6211103 2951736 5668627 0 3832569 3006180 3061269 3293412 0 5121839 4953195 3293051 5291302 0 1144959 2328015 3053677 0 3452031 4022899 3046577 5459914 5408746 3879426 +AAFDKNYAK MGYG000002293_01708;MGYG000001164_01285;MGYG000002737_00956;MGYG000003697_00295 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1260@1|root,COG1260@2|Bacteria,4NI0F@976|Bacteroidetes,2FMB3@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 I 1.0 Inositol-3-phosphate synthase 1.0 ino1 1.0 - 1.0 5.5.1.4 1.0 ko:K01858 1.0 ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130 1.0 - 1.0 R07324 1.0 RC01804 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Inos-1-P_synth,NAD_binding_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01708 0.25 inositol-3-phosphate synthase. myo-inositol-1-phosphate synthase. The NAD(+) dehydrogenates the -CHOH- group to -CO- at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the -CHO at C-1; finally, the enzyme-bound NADH reconverts C-5 into the -CHOH- form. D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. 1.0 1.0 1.0 1.0 Streptomycin biosynthesis|Inositol phosphate metabolism|Metabolic pathways 1.0 K01858:INO1, ISYNA1; myo-inositol-1-phosphate synthase [EC:5.5.1.4] 1.0 none 1.0 0 0 679727 0 0 393288 0 0 0 0 0 0 0 0 0 0 0 608199 0 0 0 428708 413451 107434 0 0 0 332506 0 0 0 0 293692 0 0 0 0 195356 0 0 305519 0 0 248112 0 0 0 0 0 0 0 0 0 0 0 234972 0 0 0 350152 0 0 0 0 0 0 0 0 0 0 233053 0 0 0 0 53463 0 0 0 0 0 289675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272690 0 551723 0 0 0 0 0 0 0 0 579447 0 0 0 0 268226 0 0 2003236 0 0 1888080 0 0 0 0 0 0 0 0 0 0 0 2628840 0 0 0 1938219 1468897 1621890 0 0 0 3101546 0 0 0 0 1448711 0 0 0 0 1487224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFDYC(Carbamidomethyl)VENIR MGYG000001627_00502;MGYG000003937_00374;MGYG000000084_00490 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001627_00502 0.3333333333333333 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 349278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 744303 0 0 0 0 538279 0 0 0 0 1473620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFE(Glu->Asp)KFMETK MGYG000002274_02671 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_I|m__MGYG000002274 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002274_02671 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 69141 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3184323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1658050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1817554 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEAIDQN(Deamidated)TVR MGYG000004866_01550;MGYG000003937_01091;MGYG000000084_00623;MGYG000002059_01523;MGYG000001761_00369 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004866_01550 0.2 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1993339 0 1825383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEAIDQNT(Thr->Ala)VR MGYG000004866_01550;MGYG000003937_01091;MGYG000000084_00623;MGYG000002059_01523;MGYG000001761_00369 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004866_01550 0.2 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4145320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 229812 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEAIDQNTVR MGYG000004866_01550;MGYG000003937_01091;MGYG000000084_00623;MGYG000002059_01523;MGYG000001761_00369 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004866_01550 0.2 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 4367722 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 348892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2287814 0 0 0 0 0 0 0 0 0 2426335 0 4604511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4693682 0 0 0 0 0 2986975 0 0 0 0 3324426 0 0 0 0 4064727 0 2055339 0 0 0 0 0 0 0 0 +AAFEAVDQAA(Ala->Ser)IR MGYG000003899_01136 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539945|m__MGYG000003899 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003899_01136 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 1439813 0 0 0 0 0 0 1197022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEAVDQE(Glu->Ala)TVR MGYG000001300_00295;MGYG000003166_01334 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00295 0.5 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 1105589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1335191 0 0 0 0 0 0 0 0 0 0 0 0 352962 0 0 0 0 0 0 0 0 545177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 562020 0 0 0 0 0 0 0 0 0 0 0 0 607328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2240401 0 0 0 0 3753755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4129601 0 0 0 0 0 0 0 0 0 3934117 0 0 0 0 0 320150 0 0 0 0 +AAFEAVDQE(Glu->Asn)TIR MGYG000000039_00171;MGYG000000022_01324;MGYG000004679_00524;MGYG000002040_01715;MGYG000001255_01114 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000039_00171 0.2 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 597158 0 0 0 575533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 529666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 818247 0 0 0 0 896286 0 0 1706048 0 0 0 1901099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1079624 0 0 0 0 1452643 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339976 0 0 0 0 0 +AAFEAVDQE(Glu->Gln)TVR MGYG000001300_00295;MGYG000003166_01334 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00295 0.5 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2224764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEAVDQE(Glu->Gly)TIR MGYG000000039_00171;MGYG000000022_01324;MGYG000004679_00524;MGYG000002040_01715;MGYG000001255_01114 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000039_00171 0.2 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1111527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6107724 0 0 0 0 6062760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1758810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3786452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEAVDQETI(Xle->Val)R MGYG000000039_00171;MGYG000000022_01324;MGYG000004679_00524;MGYG000002040_01715;MGYG000001255_01114 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000039_00171 0.2 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3731171 0 2254089 3261002 0 0 0 0 0 1575673 0 0 0 2321005 0 0 0 0 0 2298589 0 1298972 0 1521905 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11808844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEAVDQETIR MGYG000000039_00171;MGYG000000022_01324;MGYG000004679_00524;MGYG000002040_01715;MGYG000001255_01114 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000039_00171 0.2 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 626037 0 0 1017929 0 451694 0 0 574757 0 864830 0 0 0 0 0 0 0 0 721517 0 638979 0 0 0 0 163521 0 0 0 443255 0 0 0 0 258071 0 0 0 3002187 0 1400908 1706604 0 0 0 0 0 1086499 0 0 0 0 8957515 0 0 0 1273577 10727583 0 0 0 0 8564849 0 0 0 0 0 0 0 0 0 0 1673510 0 1389720 1499422 1031147 1158821 1070478 1477305 0 1604340 1111937 0 1101516 1409833 0 0 0 3609104 0 1136960 0 1347988 3720639 1244998 1838131 1912653 0 3869085 1209561 0 0 0 1099335 1831098 2407724 0 1779528 984300 0 0 0 0 1221442 1045285 836437 764399 0 1590336 758279 0 0 0 0 0 0 1710896 0 781694 0 756402 1836547 890126 0 683432 0 1504996 1661612 0 0 0 1468098 0 0 0 894654 1324692 0 0 0 0 585563 0 0 0 0 1600466 0 0 0 0 0 0 0 7625771 0 0 0 6017650 8440453 0 1189305 0 0 9317366 1079338 0 0 0 0 1272874 5697177 0 0 6368474 +AAFEAVDQETV(Val->Xle)R MGYG000001300_00295;MGYG000003166_01334 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00295 0.5 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1231124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1096332 0 0 0 0 0 0 0 0 3602774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1853401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEAVDQETVR MGYG000001300_00295;MGYG000003166_01334 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00295 0.5 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 14992539 18575043 28815378 26545334 2665685 11763186 10455312 7138001 13354323 14037801 9581939 0 18210118 14143546 11821315 16337275 17154233 3781717 28138188 22775286 5286537 12577168 4148690 14200905 15937489 15773126 14957306 5574330 1345855 5775835 16422982 9556687 23872411 24045499 7271686 13950578 11702730 21896039 22117278 32720129 31967734 17874800 19661062 37145527 28214444 8756602 24704588 3653247 15662968 23600032 27380359 27944587 23934865 19698725 24046017 4348424 30396088 24570211 9127581 31512821 5510683 35420297 39184233 18909129 19177387 5329529 3516838 21559661 39198566 31648552 36801887 22104868 7350890 19676812 19314836 30251071 0 3847225 0 0 0 0 3718738 1981754 3038864 0 3689522 0 3563733 0 2355852 2771126 0 0 2428647 0 2202934 0 3736683 0 2020711 0 0 4028161 1046385 2406636 4060155 0 0 4247069 0 2712223 2720762 0 12474954 15858838 30227632 13465160 22806731 20811364 24815545 4318961 21035242 14039768 17775982 31232110 24739895 18535163 15035606 18014614 15230092 11117674 26754555 17545658 18177018 16713765 0 15229321 19449311 16012096 13528197 9502637 5897900 21527731 30271511 20060462 31516521 24344892 2535813 12827010 18440282 28446115 349607 0 398085 466250 139819 0 0 384999 0 1089163 0 686597 0 0 415854 0 277145 1282408 0 374217 557136 0 1919981 635597 547579 299704 0 1395367 654726 0 509861 0 551762 335165 0 550423 602793 0 +AAFEAVDQN(Deamidated)TIR MGYG000002274_00044 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_I|m__MGYG000002274 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_00044 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 7798530 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2769374 1198303 0 0 0 0 0 2193406 0 0 0 0 1680514 4596584 0 0 3362403 0 0 0 0 2954412 2260139 0 0 0 0 3315347 0 0 0 0 0 2324620 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1803891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEAVDQNTIR MGYG000002274_00044 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_I|m__MGYG000002274 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_00044 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 2884964 0 3548911 0 4044108 3371897 0 0 3696156 0 4291223 2891330 4110249 0 0 0 0 7115641 0 0 3377611 3474931 4940275 3121669 0 4305602 0 6461025 0 0 2057127 0 2763489 0 0 2850245 3060948 3153008 0 0 567155 0 322307 557440 0 0 645796 0 472475 432631 409127 0 0 0 0 939692 0 0 406180 0 728911 386540 0 0 0 736881 0 0 524382 0 0 0 0 429006 566634 265315 0 0 4775212 0 4229804 3531666 0 0 1918409 0 1553251 5773538 1797072 0 0 0 0 2326173 0 0 5335352 0 2274193 3589657 0 1425979 0 942094 0 0 4556671 0 3104614 0 0 4909671 5711891 5272212 0 0 0 0 2045886 0 0 0 1193876 0 6673114 0 0 0 0 0 0 8450030 0 0 0 0 9794438 7654821 0 0 0 11094775 0 0 6264364 0 5427734 0 0 4268971 0 5897835 305179 0 0 0 0 381100 0 0 0 0 0 0 868992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 965660 0 0 0 0 0 0 0 +AAFEAVDQSAIR MGYG000002545_00548 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_G|m__MGYG000002545 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002545_00548 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5567988 0 0 0 0 5877396 0 0 0 0 5916066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7560821 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEAYK MGYG000003012_02916;MGYG000000133_02295;MGYG000001338_02552 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XZ67@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 E 1.0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins 1.0 iscS 1.0 - 1.0 2.8.1.7 1.0 ko:K04487 1.0 ko00730,ko01100,ko04122,map00730,map01100,map04122 1.0 - 1.0 R07460,R11528,R11529 1.0 RC01789,RC02313 1.0 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003012_02916 0.3333333333333333 cysteine desulfurase. cysteine desulfurylase. The sulfur from free L-cysteine is first transferred to a cysteine residue in the active site, and then passed on to various other acceptors.-!-The enzyme is involved in the biosynthesis of iron-sulfur clusters, thio-nucleosides in tRNA, thiamine, biotin, lipoate and pyranopterin (molybdopterin).-!-In Azotobacter vinelandii, this sulfur provides the inorganic sulfide required for nitrogenous metallocluster formation. [sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine. 1.0 1.0 1.0 1.0 Thiamine metabolism|Metabolic pathways|Sulfur relay system 1.0 K04487:iscS, NFS1; cysteine desulfurase [EC:2.8.1.7] 1.0 none 1.0 808506 1061689 0 957907 0 1044617 0 0 0 0 755273 614980 1004837 1214072 0 1460935 0 0 0 0 1023454 782691 0 1188920 0 754077 0 0 690719 0 1949762 1081725 0 0 0 0 1044137 0 436955 0 299250 184327 0 97070 0 0 0 0 246055 0 332629 204864 0 245137 0 0 0 0 219161 153993 0 345471 0 0 0 0 146835 0 0 116124 372004 0 0 0 0 0 0 0 0 0 0 543923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122431 0 0 0 0 0 0 0 119707 0 0 0 0 127109 0 0 0 0 0 0 0 394230 0 0 0 0 0 0 0 0 0 0 0 0 0 214412 958277 2213292 1372525 1872831 0 753181 0 0 0 0 2015262 1644062 1374152 1646396 0 1602837 0 0 0 0 2537903 1987298 0 1104742 0 930256 0 0 1338491 0 1356695 3040879 2935430 0 0 0 544395 1131219 +AAFEEAEHAAK MGYG000003509_00509;MGYG000000177_00118;MGYG000002026_00456;MGYG000003891_00390;MGYG000004769_01404;MGYG000000198_03730;MGYG000000172_04155;MGYG000004087_01663;MGYG000001434_00926;MGYG000000198_03710;MGYG000004087_01662;MGYG000001564_01103;MGYG000001311_01511;MGYG000001493_02801;MGYG000001493_02800;MGYG000003422_00075;MGYG000004713_00792 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,21YU6@1506553|Lachnoclostridium 0.5294117647058824 186801|Clostridia 0.8823529411764706 C 1.0 Rubrerythrin 0.6470588235294118 rbr3A 0.9411764705882353 - 0.9411764705882353 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.8823529411764706 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003509_00509 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 4244759 4202530 3211781 4121308 2802847 3042565 2926887 3356840 3304269 4015268 3342626 3458009 3050535 3521301 3110091 3230034 2695244 4320894 3107643 3797249 4623841 3213635 671684 3478431 2945439 3148586 2981065 4679049 3533223 3742562 892899 2802056 2456742 3628139 2862794 2685399 3635889 2587444 1266167 1268699 1314355 946176 1378790 1666185 1177722 1236139 1350914 1517036 1872186 1205285 1412866 1267281 1106236 1353098 1516234 841395 1184617 1027979 1339901 1274189 783561 1538306 1085844 1170023 1143072 807452 1374248 381269 1457499 1227130 1575609 1274384 1076668 1189678 1262666 1489539 5321852 3431710 4223115 4291332 3736855 3440077 4159373 4702742 4148994 5345754 3592989 3508718 3437321 4789199 5189881 3714105 3411648 957039 5001065 5294758 4281467 3264152 2882092 4662580 4034945 5718979 5226269 2907574 4279975 4211620 3296294 3457139 4229335 4606746 2664041 4610412 4467945 3847457 1250174 1039053 1819252 753964 1327109 1537145 1107847 1176505 1031254 1940913 1509225 1365401 1792126 1113118 1057493 1152941 1276068 1537116 1569451 733681 1228693 1430052 1044890 1884401 1314585 1458003 1133738 1746560 1500769 1079524 1394059 1545177 2361605 1337829 1248903 1878718 1195835 1789601 4803013 3125577 3865891 8069281 4358963 3986457 4802657 3715600 5672067 5726838 4527540 3963163 4292895 4763740 5295242 2877745 5900433 2330182 3803472 5389732 3782577 4913342 3339353 5607617 4730417 7405878 5528896 0 3134379 4138779 4651561 4162578 3911753 5263109 2915746 8074649 5761429 4489780 +AAFEGETGK MGYG000000187_00431 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,25VUF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000187_00431 1.0 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1277163 0 0 0 0 1276880 0 0 0 0 1149829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251261 0 0 0 0 346953 0 0 0 0 343161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 355390 0 0 0 0 585811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 512326 0 0 0 0 1022335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEGVTGQMVALKR MGYG000002224_01133;MGYG000002651_00394;MGYG000002641_02047;MGYG000000022_01099 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3WHGE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002224_01133 0.25 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481237 0 0 0 0 689118 0 0 0 0 627594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582130 0 0 0 0 674971 0 0 0 0 703303 0 0 0 0 0 0 0 0 0 0 +AAFEHAK MGYG000000074_02552 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0696@1|root,COG0696@2|Bacteria,4NEQT@976|Bacteroidetes,2FMVJ@200643|Bacteroidia,22UAM@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate 1.0 gpmI 1.0 - 1.0 5.4.2.12 1.0 ko:K15633 1.0 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01518 1.0 RC00536 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DUF1398,Metalloenzyme,PglZ,Phosphodiest,iPGM_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02552 1.0 phosphoglycerate mutase (2,3-diphosphoglycerate-independent). phosphoglyceromutase. The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate. cf. EC 5.4.2.11.-!-The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.-!-Both metal ions are involved in the reaction.-!-Formerly EC 2.7.5.3 and EC 5.4.2.1. (2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K15633:gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 46842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84024 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 491041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEKGEKAE MGYG000001300_01309 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WGTC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 P 1.0 Belongs to the ABC transporter superfamily 1.0 oppD 1.0 - 1.0 - 1.0 ko:K15583 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 ABC_tran,oligo_HPY 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_01309 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K15583:oppD; oligopeptide transport system ATP-binding protein 1.0 none 1.0 272219 0 0 524631 0 407501 225068 0 0 0 0 0 0 0 0 0 0 0 623506 420234 0 231940 0 246788 234953 225488 326222 0 0 0 0 0 0 0 0 0 372697 0 584791 0 0 828032 0 448319 991378 0 0 0 0 0 0 0 0 0 0 0 879299 671581 0 176802 0 230651 951398 717372 740764 0 0 0 0 0 0 0 0 0 547304 0 31864 0 0 131670 0 477206 73463 0 0 0 0 0 0 0 0 0 0 0 304498 316594 0 451705 0 0 462808 481561 225051 0 0 0 0 0 0 0 0 0 175808 0 599605 0 0 526285 0 696576 545993 0 0 0 0 0 0 0 0 0 0 0 622068 569007 0 686207 0 487953 580558 710503 512135 0 0 0 0 0 0 0 0 0 248991 0 464190 0 0 797299 0 675337 812715 0 0 0 0 0 0 0 0 0 0 0 344284 367291 0 417327 0 563400 516582 723773 346432 0 0 0 0 0 0 0 0 0 828466 0 +AAFESVK MGYG000003891_01893 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG2730@1|root,COG2730@2|Bacteria,1UYCF@1239|Firmicutes,24989@186801|Clostridia,27KIY@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Cellulase (glycosyl hydrolase family 5) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Cellulase,RicinB_lectin_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_01893 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1405973 0 0 0 0 1567497 0 0 0 0 1430597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320275 0 0 0 0 115878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 960997 0 0 0 0 496947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFEYAQNTLNQTK MGYG000002438_03281 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0845@1|root,COG0845@2|Bacteria,4NIZF@976|Bacteroidetes,2FN5T@200643|Bacteroidia,22Y8A@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03281 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1333263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 790584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1752517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFFIC(Carbamidomethyl)GADR MGYG000003022_00152;MGYG000003352_02357 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG1473@1|root,COG1473@2|Bacteria,1MUIV@1224|Proteobacteria,2VZYA@28216|Betaproteobacteria,4PQ6E@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 E 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003022_00152 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 214091 0 200177 0 255978 0 0 302307 0 0 0 0 0 0 0 0 0 0 0 272355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155122 0 0 113827 990938 0 727168 0 1011174 0 1012769 1696469 800654 973170 0 0 0 0 0 0 0 0 851911 854058 0 0 0 0 0 798258 0 0 882942 0 0 0 897316 0 1404997 0 996015 861469 411732 0 409451 0 486320 0 455624 1195931 532849 339233 0 0 0 0 0 0 0 0 524222 197430 0 0 0 0 0 485387 0 0 424725 0 0 0 564789 0 1530316 0 669396 452803 276171 0 330521 0 210909 0 181153 300002 460858 221031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311119 0 0 161315 0 0 0 190298 0 322665 0 321224 281807 108503 0 447357 0 199647 0 207424 200003 242705 0 0 0 0 0 0 0 0 0 410035 215153 0 0 0 0 0 188867 0 0 290696 0 0 0 253224 0 395408 0 315610 277332 +AAFFMDDYIGGR MGYG000000212_02891;MGYG000002492_00205;MGYG000000251_02552;MGYG000002279_01884;MGYG000000389_01919;MGYG000002992_01779 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 G 0.8333333333333334 Belongs to the GPI family 0.3333333333333333 pgi 0.8333333333333334 - 1.0 2.2.1.2,5.3.1.9 0.8333333333333334 ko:K01810,ko:K13810 0.8333333333333334 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230 0.8333333333333334 M00001,M00004,M00007,M00114 0.8333333333333334 R01827,R02739,R02740,R03321 0.8333333333333334 RC00376,RC00439,RC00563,RC00604 0.8333333333333334 ko00000,ko00001,ko00002,ko01000,ko04147 0.8333333333333334 - 1.0 - 1.0 - 1.0 PGI,TAL_FSA 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_02891 0.16666666666666666 transaldolase. | glucose-6-phosphate isomerase. glycerone transferase. | phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. | alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.8333333333333334 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]|K13810:tal-pgi; transaldolase / glucose-6-phosphate isomerase [EC:2.2.1.2 5.3.1.9] 0.8333333333333334 none 1.0 0 0 312390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 784250 0 864694 0 0 0 529993 0 621934 0 0 0 509692 0 0 509422 0 0 0 761353 0 0 0 0 824817 700847 657152 0 0 0 0 0 782173 807783 766417 853747 790108 743231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFGDTLVEDYNVR MGYG000000089_01490 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3WGIF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 1.0 rpsC 1.0 - 1.0 - 1.0 ko:K02982 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000089_01490 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02982:RP-S3, rpsC; small subunit ribosomal protein S3 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1138421 0 0 0 0 1219987 0 0 0 0 1531169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFGLK MGYG000001496_03152 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Extibacter|s__Extibacter sp001185345|m__MGYG000001496 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001496_03152 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575423 0 0 0 0 560257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFGVILINTK MGYG000001346_02330 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_02330 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 324270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 538110 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 677649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFGVILITTK MGYG000002171_02947;MGYG000000243_00119 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_02947 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 411851 533608 1291544 691437 543238 0 0 528234 673355 0 314897 466011 0 0 0 323316 636554 0 0 0 0 0 0 0 0 393160 470258 0 712959 0 1191754 548734 1167538 711331 0 513300 575703 1180485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159481 0 253871 115153 447261 0 0 105208 270357 0 284905 328201 0 0 0 243450 0 0 0 0 0 0 0 0 0 123185 0 0 207555 0 374895 0 145447 0 0 280601 257271 190619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFGVILVTTK MGYG000000042_02037;MGYG000002478_01844;MGYG000001415_00852;MGYG000002478_00434;MGYG000001337_00976;MGYG000001337_04109;MGYG000002203_01364;MGYG000000003_01805;MGYG000003279_01059;MGYG000000236_03728;MGYG000000273_01279;MGYG000003363_02700;MGYG000004756_00447;MGYG000000236_01449 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.7857142857142857 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,CarboxypepD_reg,Plug,STN,TonB_dep_Rec 0.5714285714285714 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_02037 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1566280 2081402 1235950 2114886 1171273 1788056 1511705 1231955 1986967 2214013 987007 2683014 1318443 1511615 1874270 1413801 2273872 0 1361837 1342594 1854483 1501648 0 2116324 1819190 2128297 2912127 0 1743753 3587455 1725404 1857143 1417438 1130496 1746143 1790730 2107879 1132454 0 0 146799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147834 0 0 0 0 0 0 0 0 0 161395 0 0 0 0 0 0 1839379 876981 1736240 1542235 1605077 669634 2138927 1823036 1993525 1479763 1106781 1993201 1138519 1640000 1716233 878986 1042234 0 1529715 2184215 2083311 645919 0 1124969 1685033 1645607 1645655 0 1509312 2527068 1012666 800230 1636976 2172099 1462686 2406950 1722247 1713121 213968 0 0 0 110858 0 138114 198060 123476 111109 0 310951 192966 215287 182568 118665 0 0 139577 150290 198329 0 0 0 301431 301313 193498 0 0 0 131803 253961 259669 367962 167319 245541 441507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFGVVLITTK MGYG000000236_00639;MGYG000003693_02994;MGYG000001780_03070;MGYG000001313_00646;MGYG000002171_00975;MGYG000000243_01524;MGYG000001787_00483;MGYG000003681_02851;MGYG000001364_00903;MGYG000000243_02728;MGYG000000138_01891 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.9090909090909091 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6363636363636364 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_00639 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 1186613 662410 420244 0 0 0 0 0 0 0 390474 401793 0 0 531874 0 0 0 0 0 322651 0 0 0 0 308522 0 0 790728 0 1306349 0 0 0 0 1072723 0 0 190355 306056 247961 0 0 0 0 0 0 0 179793 437613 0 0 117904 1459182 0 0 0 0 1722660 0 0 0 0 1046747 0 0 0 0 144817 0 0 0 0 315691 0 0 358547 309666 589292 0 0 0 0 0 0 0 415327 582671 0 0 214339 767365 0 0 0 0 786290 0 0 0 0 635178 0 0 530770 0 435501 0 0 0 0 558931 0 0 259330 187926 0 0 0 0 0 0 0 0 86162 386055 0 0 93690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFIEPTYTDDHKEVFR MGYG000000243_00625 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0436@1|root,COG0436@2|Bacteria,4PNG6@976|Bacteroidetes,2G0SS@200643|Bacteroidia,4AVDR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00625 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 1200017 0 0 0 0 0 648353 0 0 0 0 0 0 643494 0 508553 0 0 0 0 602446 0 0 0 0 759309 0 0 0 0 1777651 0 0 0 0 1096268 0 0 303212 0 0 0 0 0 449218 0 0 0 0 0 0 569312 0 69339 0 0 0 0 88845 0 0 0 0 164493 0 0 0 0 238857 0 0 0 0 420892 0 0 486214 0 0 0 0 0 463585 0 0 0 0 0 0 764820 0 1084765 0 0 0 0 1148009 0 0 0 0 851040 0 0 0 0 342658 0 0 0 0 570061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFILPK MGYG000000042_00112;MGYG000003351_02824;MGYG000000013_01592;MGYG000001345_00708;MGYG000003363_00794;MGYG000001364_03030;MGYG000001337_03360;MGYG000000273_00592;MGYG000000243_03061;MGYG000001313_02816;MGYG000001306_02021;MGYG000004876_02630;MGYG000001469_02540;MGYG000000098_03289;MGYG000002218_02429;MGYG000000236_02271;MGYG000003922_03784;MGYG000002455_01260;MGYG000000196_02850;MGYG000004797_00528;MGYG000004748_01740;MGYG000002614_00510;MGYG000000105_02714;MGYG000002540_02630;MGYG000001783_00321;MGYG000003681_00501;MGYG000001750_00812;MGYG000004899_03438;MGYG000001378_01736;MGYG000000127_02932;MGYG000002171_03034;MGYG000001780_02719;MGYG000001925_00352 domain d__Bacteria 1.0 COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,2FMPF@200643|Bacteroidia,4AMNF@815|Bacteroidaceae 0.8787878787878788 976|Bacteroidetes 0.9393939393939394 L 0.9393939393939394 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria 0.9393939393939394 dnaN 0.9393939393939394 - 1.0 2.7.7.7 0.9393939393939394 ko:K02338 0.9393939393939394 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 0.9393939393939394 M00260 0.9393939393939394 R00375,R00376,R00377,R00378 0.9393939393939394 RC02795 0.9393939393939394 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 0.9393939393939394 - 1.0 - 1.0 - 1.0 DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 0.9393939393939394 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_00112 0.030303030303030304 DNA-directed DNA polymerase. DNA nucleotidyltransferase (DNA-directed). Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.-!-Cannot initiate a chain de novo.-!-Requires a primer which may be DNA or RNA.-!-See also EC 2.7.7.49. a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1). 0.9393939393939394 0.9393939393939394 0.9393939393939394 0.9393939393939394 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|DNA replication|Mismatch repair|Homologous recombination 0.9393939393939394 K02338:dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] 0.9393939393939394 none 1.0 0 0 3216895 2529619 2659441 2375500 2771207 2234658 2329774 1997139 2408757 2074320 0 0 1790508 0 2580567 1489604 2048113 2174816 2480994 2303758 2171905 3132941 0 2228882 0 1718978 2339593 2372742 3427451 0 3717031 2425745 0 2648026 2413846 3757366 2492462 0 2639721 2690107 2425566 2212189 2177732 2846194 2923082 2888717 3273635 2770362 0 0 3066629 2476755 2731968 1828974 2592856 2377085 2666939 2436869 3178964 1800147 0 2807627 0 2447473 2081554 2642712 1420630 0 2486935 2378659 2819942 2504566 2744743 2651221 2340566 0 2753783 2493791 3785255 3038159 3413086 2206059 3094661 2201113 3003701 3412057 0 0 2175435 2613345 2572734 4648178 2376541 2253237 2480251 1901691 3939977 3500602 0 2521699 0 3241232 2979790 2536255 3254986 0 1979599 1820479 2585435 2806444 2498222 2541637 1479597 0 1356961 1270590 0 0 1620898 1779392 1259623 1367699 1388259 1727941 0 0 1451589 0 1225952 1451947 1414648 994521 1448180 0 1999576 1138348 0 1425126 0 723633 1286093 1230182 1147266 0 1304524 1982381 1713688 2009545 1578260 1031949 1743824 0 1366846 1903023 2909568 2461685 1975251 2311661 2173788 1501902 1938292 1545978 0 0 1605564 1971624 1943617 4019593 1428950 2301696 1303880 2202152 3837636 2981090 0 1496273 0 3085999 1988478 0 1663053 0 945079 2430614 2171471 1493115 1861265 1562717 +AAFK(Lys->Asn)TNFQER MGYG000004797_01285 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia,22W91@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 CarboxypepD_reg-like domain 1.0 susC 1.0 - 1.0 - 1.0 ko:K21573 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14.6.1 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01285 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21573:susC; TonB-dependent starch-binding outer membrane protein SusC 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1561630 0 0 0 0 0 0 0 0 0 579179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 627838 0 0 0 0 762347 0 0 0 0 329056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4027979 0 0 0 0 3019767 0 0 0 0 2014517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFKTDNPIEEMGIK MGYG000001346_02121;MGYG000004876_03122;MGYG000004797_02542 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,4NEP3@976|Bacteroidetes,2FN08@200643|Bacteroidia,4AM9Z@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 2-oxoacid acceptor oxidoreductase, alpha subunit 1.0 porA 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00174 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFOR_II,POR,POR_N,Transketolase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_02121 0.3333333333333333 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00174:korA, oorA, oforA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 123088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 555768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFLGSEDAQLAHFK MGYG000002492_00484 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC transporter, solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00484 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K15770:cycB, ganO, mdxE; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1376220 0 0 0 0 852263 0 0 0 0 763976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFLLPK MGYG000000236_02271;MGYG000003351_02824;MGYG000000013_01592;MGYG000002455_01260;MGYG000000196_02850;MGYG000004756_00320;MGYG000004797_00528;MGYG000001372_00582;MGYG000003367_02648;MGYG000001345_00708;MGYG000001783_00321;MGYG000001388_00629;MGYG000003363_00794;MGYG000001337_03360;MGYG000000243_03061;MGYG000004876_02630;MGYG000001469_02540;MGYG000001835_01004;MGYG000001370_00874;MGYG000000127_02932 domain d__Bacteria 1.0 COG0592@1|root,COG0592@2|Bacteria,4NESB@976|Bacteroidetes,2FMPF@200643|Bacteroidia,4AMNF@815|Bacteroidaceae 0.75 976|Bacteroidetes 0.85 L 0.85 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria 0.85 dnaN 0.85 - 1.0 2.7.7.7 0.85 ko:K02338 0.85 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 0.85 M00260 0.85 R00375,R00376,R00377,R00378 0.85 RC02795 0.85 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 0.85 - 0.95 - 1.0 - 1.0 DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 0.85 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_02271 0.05 DNA-directed DNA polymerase. DNA nucleotidyltransferase (DNA-directed). Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.-!-Cannot initiate a chain de novo.-!-Requires a primer which may be DNA or RNA.-!-See also EC 2.7.7.49. a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1). 0.85 0.85 0.85 0.85 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|DNA replication|Mismatch repair|Homologous recombination 0.85 K02338:dnaN; DNA polymerase III subunit beta [EC:2.7.7.7] 0.85 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2375961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFM(Oxidation)PQAEK MGYG000002223_00929;MGYG000001300_00132;MGYG000002641_00308 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002223_00929 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 596368 0 467737 417867 0 0 313134 0 303102 0 0 0 0 0 0 0 0 0 594251 0 0 0 0 0 233075 363725 0 0 0 0 0 0 578872 0 0 0 366275 533039 511878 0 681403 613422 0 0 1013846 0 1833916 0 0 565099 0 0 0 0 0 0 899616 0 0 0 0 0 846687 671278 0 0 0 0 0 0 733608 0 0 0 975171 863573 249544 0 0 127862 0 0 484707 0 394155 0 0 0 0 0 0 0 0 0 119508 0 0 0 0 0 161380 0 0 0 0 0 0 0 0 0 0 0 0 0 731075 0 822549 578853 0 0 1012312 0 733270 0 0 1040163 0 0 0 0 0 0 839307 0 0 0 0 0 653103 482778 0 0 0 0 0 0 812399 0 0 0 574062 427691 0 0 157481 0 0 0 0 0 405240 0 0 488092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFMPQAEK MGYG000002223_00929;MGYG000001300_00132;MGYG000002641_00308 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002223_00929 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 3264509 3462708 4500167 4478205 626089 2827178 2924233 2223521 3516126 2864494 1593632 838444 2630783 3993072 1969267 2121644 3167593 1116862 4152876 3915264 603258 2455894 1025826 4068618 3168196 3372417 3155947 881731 0 282974 3507532 2372453 4044308 4878050 1605254 3072201 2784912 3992104 8103806 6621774 7507742 7965971 4722833 6083891 9852114 4165962 7828478 1007258 3158181 5840124 4643619 10240420 6886608 4330804 9581990 1741039 10763512 8269484 2760117 3663877 1537657 5447261 9177536 8179371 6947374 1668610 0 4755969 5633448 5104243 7840851 7697897 4045749 7331537 7831108 5869988 1546184 1140062 847476 1923541 988583 0 2260309 735193 1124820 682870 1391490 737329 1820307 2102474 1047280 851639 591471 749806 608857 1095983 465228 780695 715616 433325 625475 1235940 785205 936456 0 335028 1164215 943337 666986 1918494 218506 1262792 1121326 619813 3195668 3164704 4224682 3631126 3624367 5360920 5963204 2682589 3935452 3913583 3601302 5047180 4994172 3717361 3652508 3776451 3255896 1343503 4373369 3394048 3511305 4863248 1556695 4158738 3802312 3877750 3228584 1585177 0 4370331 4587132 3204446 4552535 5272204 1839031 3035387 3579500 4204917 0 207118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119418 0 0 0 878441 0 0 0 0 265063 0 0 0 0 0 0 0 0 0 0 +AAFNAQATK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01126 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 815268 0 169707 445556 257096 229097 0 231878 271322 309920 0 87381 0 506467 229900 408491 0 0 310820 735041 544799 431194 0 269035 0 533423 510833 0 522200 335247 0 0 0 495298 665027 549356 534167 674017 9087969 3817244 6102920 9342143 4653224 3261455 0 7463001 8338944 7896838 4299447 6607375 0 8444132 9294820 3523712 0 0 7631843 8119398 6278260 2934013 0 3255589 6897405 9239609 7848244 0 6297051 5767283 0 4490819 5758911 7137573 6234869 7714426 8602223 4318666 324004 0 0 0 0 0 0 0 1046773 0 153418 97932 0 286744 551470 0 0 0 960350 0 533872 0 0 679783 0 393738 500564 0 0 0 0 0 0 0 0 0 0 535440 1960639 711318 1765925 1470708 860531 0 0 1793541 1142261 1759603 662076 1562547 0 1117724 2154557 988191 0 0 1640487 1301066 1103856 0 0 0 1754169 2241902 1472255 0 1322969 1681579 0 1290896 1761000 0 2546416 1980733 1915197 787820 0 668652 0 0 959584 757578 0 551310 595158 589617 70554 545514 0 483662 885503 651498 0 0 653014 1157985 411353 319209 0 358566 976498 832254 643719 0 1095951 278392 0 405254 236923 0 302445 965623 0 0 +AAFNDFSK MGYG000002494_04635 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG4105@1|root,COG4105@2|Bacteria,1MVS5@1224|Proteobacteria,1RSE6@1236|Gammaproteobacteria,3XN5M@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 M 1.0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery 1.0 bamD 1.0 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 1.0 - 1.0 ko:K05807 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.33.1 1.0 - 1.0 - 1.0 TPR_18,TPR_6,YfiO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04635 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K05807:bamD; outer membrane protein assembly factor BamD 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1160777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1256097 0 1135882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFPEKTFGEEMKPGTLGFGSTIFAVKPGDGSAR MGYG000002517_03119 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 aconitate hydratase 1.0 ybhJ 1.0 - 1.0 4.2.1.3 1.0 ko:K01681 1.0 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 1.0 M00009,M00010,M00012,M00173,M00740 1.0 R01324,R01325,R01900 1.0 RC00497,RC00498,RC00618 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aconitase,Aconitase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_03119 1.0 aconitate hydratase. citrate hydro-lyase. Besides interconverting citrate and cis-aconitate, it also interconverts cis-aconitate with isocitrate and, hence, interconverts citrate and isocitrate.-!-The equilibrium mixture is 91% citrate, 6% isocitrate and 3% aconitate.-!-cis-aconitate is used to designate the isomer (Z)-prop-1-ene-1,2,3- tricarboxylate.-!-Formerly EC 4.2.1.4. citrate = D-threo-isocitrate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Glyoxylate and dicarboxylate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K01681:ACO, acnA; aconitate hydratase [EC:4.2.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFPIIK MGYG000001164_02228 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella lascolaii|m__MGYG000001164 1.0 COG0479@1|root,COG0479@2|Bacteria,4NFR3@976|Bacteroidetes,2FP6Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Succinate dehydrogenase Fumarate reductase 1.0 frdB 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00240 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer2_3,Fer4_7,Fer4_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001164_02228 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00240:sdhB, frdB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1246400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFPLEWLHDSK MGYG000002438_02897 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,4NEDE@976|Bacteroidetes,2FKZJ@200643|Bacteroidia,22W2V@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the GcvP family 1.0 gcvP 1.0 - 1.0 1.4.4.2 1.0 ko:K00281,ko:K00283 1.0 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 1.0 M00532 1.0 R01221,R03425 1.0 RC00022,RC00929,RC02834,RC02880 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5,GDC-P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02897 1.0 glycine dehydrogenase (aminomethyl-transferring). glycine dehydrogenase (decarboxylating). A component of the glycine cleavage system, which is composed of four components that only loosely associate: the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H protein.-!-Previously known as glycine synthase. glycine + H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[glycine-cleavage complex H protein] = CO2 + N(6)-[(R)-S(8)-aminomethyldihydrolipoyl]-L-lysyl- [glycine-cleavage complex H protein]. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Glyoxylate and dicarboxylate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Carbon metabolism 1.0 K00281:GLDC, gcvP; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]|K00283:gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223118 0 0 0 75918 0 0 0 0 261551 0 0 0 0 0 0 0 0 188046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 48200 0 0 0 0 0 0 0 0 125553 0 0 0 0 0 0 0 0 56605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 43304 0 0 0 71995 0 0 0 0 179354 0 0 0 0 0 0 0 0 51859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256721 0 0 0 237374 0 0 0 0 447150 0 0 0 0 0 0 0 0 347728 0 0 0 0 0 0 0 0 +AAFPLSLSQEAQIAQSR MGYG000002494_04631 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0722@1|root,COG0722@2|Bacteria,1MU5Q@1224|Proteobacteria,1RMAA@1236|Gammaproteobacteria,3XMUR@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) 1.0 aroF 1.0 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 2.5.1.54 1.0 ko:K01626 1.0 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 1.0 M00022 1.0 R01826 1.0 RC00435 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_3932,iECOK1_1307.ECOK1_2946,iECS88_1305.ECS88_2787,iLF82_1304.LF82_0146,iNRG857_1313.NRG857_03335,iSbBS512_1146.SbBS512_E1908,iUMN146_1321.UM146_03705,iUTI89_1310.UTI89_C2934 1.0 DAHP_synth_1,P22_Cro 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04631 1.0 3-deoxy-7-phosphoheptulonate synthase. phospho-2-oxo-3-deoxyheptonate aldolase. Formerly EC 4.1.2.15. D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2- dehydro-3-deoxy-D-arabino-heptonate + phosphate. 1.0 1.0 1.0 1.0 Phenylalanine, tyrosine and tryptophan biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids|Quorum sensing 1.0 K01626:E2.5.1.54, aroF, aroG, aroH; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232836 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579796 0 0 0 0 644780 1027362 0 1009410 0 0 0 1413096 0 756874 1553429 0 0 0 1502449 0 0 1920627 0 825216 0 2055159 0 0 0 1457073 945487 0 0 2300342 2145598 0 0 1164539 686706 0 931707 597460 695724 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158844 157915 0 0 0 0 0 0 0 100563 0 85468 70098 62013 +AAFPQVDVVVGNVATGEAAK MGYG000002293_02133;MGYG000003697_01312 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,4NDXQ@976|Bacteroidetes,2FMKX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO,NanE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_02133 0.5 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 578342 0 0 0 0 521075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 664730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766663 0 0 0 0 1712952 0 0 0 0 0 0 0 0 0 404000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFQA(Ala->Thr)EDVVSSHEKK MGYG000000133_01247 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3XZ6B@572511|Blautia 1.0 186801|Clostridia 1.0 P 1.0 Psort location CytoplasmicMembrane, score 1.0 actP 1.0 - 1.0 3.6.3.4,3.6.3.54 1.0 ko:K01533,ko:K17686 1.0 ko01524,ko04016,map01524,map04016 1.0 - 1.0 R00086 1.0 RC00002 1.0 ko00000,ko00001,ko01000 1.0 3.A.3.5 1.0 - 1.0 - 1.0 E1-E2_ATPase,HMA,Hydrolase,YHS 1.0 - 1.0 - 1.0 - 1.0 CBM50 1.0 MGYG000000133_01247 1.0 P-type Cu(2+) transporter. | P-type Cu(+) transporter. Cu(2+)-exporting ATPase. | Cu(+)-exporting ATPase. A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.-!-The enzyme from the termophilic bacterium Archaeoglobus fulgidus is involved in copper extrusion from the cell.-!-Formerly EC 3.6.3.4. | A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.-!-This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 7.2.2.9, which mainly transports the divalent copper ion.-!-Formerly EC 3.6.3.54 and EC 3.6.3.n1. ATP + Cu(2+)(in) + H2O = ADP + Cu(2+)(out) + H(+) + phosphate. | ATP + Cu(+)(in) + H2O = ADP + Cu(+)(out) + H(+) + phosphate. 1.0 1.0 1.0 1.0 Platinum drug resistance|MAPK signaling pathway - plant 1.0 K01533:copB; P-type Cu2+ transporter [EC:7.2.2.9]|K17686:copA, ctpA, ATP7; P-type Cu+ transporter [EC:7.2.2.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1068015 0 0 0 0 0 0 +AAFSAIPGVEVR MGYG000001300_00512 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00512 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10200:ngcE; N-acetylglucosamine transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 622878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1595232 0 0 0 0 1884434 0 0 0 0 930221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFSNDMVYMEK MGYG000002506_02896;MGYG000002477_00118;MGYG000002494_01866;MGYG000002534_00468 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0439@1|root,COG0439@2|Bacteria,1MU4H@1224|Proteobacteria,1RMNB@1236|Gammaproteobacteria,3XP5G@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 I 1.0 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA 1.0 accC 1.0 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 1.0 6.3.4.14,6.4.1.2 1.0 ko:K01961 1.0 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 1.0 M00082,M00376 1.0 R00742,R04385 1.0 RC00040,RC00253,RC00367 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iSF_1195.SF3294 1.0 Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02896 0.25 biotin carboxylase. | acetyl-CoA carboxylase. - This enzyme, part of an acetyl-CoA carboxylase complex, acts on a biotin carboxyl-carrier protein (BCCP) that has been biotinylated by EC 6.3.4.15.-!-In some organisms the enzyme is part of a multi-domain polypeptide that also includes the carrier protein (e.g. mycobacteria).-!-Yet in other organisms (e.g. mammals) this activity is included in a single polypeptide that also catalyzes the transfer of the carboxyl group from biotin to acetyl-CoA (see EC 6.4.1.2). | This enzyme is a multi-domain polypeptide that catalyzes three different activities - a biotin carboxyl-carrier protein (BCCP), a biotin carboxylase that catalyzes the transfer of a carboxyl group from hydrogencarbonate to the biotin molecule carried by the carrier protein, and the transfer of the carboxyl group from biotin to acetyl-CoA, forming malonyl-CoA.-!-In some organisms these activities are catalyzed by separate enzymes (see EC 6.3.4.14 and EC 2.1.3.15).-!-The carboxylation of the carrier protein requires ATP, while the transfer of the carboxyl group to acetyl-CoA does not. ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate. | acetyl-CoA + ATP + hydrogencarbonate = ADP + H(+) + malonyl-CoA + phosphate. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis|Pyruvate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K01961:accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14] 1.0 none 1.0 0 0 215196 0 0 403281 0 0 0 386546 0 0 0 0 0 0 0 0 0 0 0 354381 0 480749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754593 0 0 1697935 0 0 0 1078183 0 0 0 0 0 0 1070602 0 951733 0 0 1955228 0 1333992 0 0 0 0 0 0 0 0 791707 0 0 0 0 766944 0 0 209262 0 0 515817 0 0 0 339214 0 0 0 0 0 0 0 0 254890 0 0 638115 0 482478 0 0 0 0 0 0 0 0 340900 0 0 0 0 306372 0 0 0 0 0 563584 0 0 0 512158 0 0 0 0 0 0 288574 0 0 0 0 383301 0 303033 0 0 0 0 0 0 0 0 411971 0 0 0 0 144028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFTADSK MGYG000000077_00225;MGYG000000262_01201 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,25WFS@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 E 1.0 Periplasmic binding protein 1.0 braC 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00225 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 1.0 K01999:livK; branched-chain amino acid transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1737441 0 0 0 0 0 0 0 0 0 0 0 0 2902728 0 0 0 0 0 0 0 0 0 0 3081290 0 0 0 0 0 0 1992355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1446363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1363680 0 0 905322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 950256 0 0 0 0 0 0 +AAFTADSKTDFGTQLQK MGYG000000262_01201 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,25WFS@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 E 1.0 Periplasmic binding protein 1.0 braC 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_01201 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 1.0 K01999:livK; branched-chain amino acid transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFVLDAIR MGYG000000028_01617;MGYG000002528_01844 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,2680N@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation 1.0 rpsC 1.0 - 1.0 - 1.0 ko:K02982 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KH_2,Ribosomal_S3_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000028_01617 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02982:RP-S3, rpsC; small subunit ribosomal protein S3 1.0 none 1.0 149473 502030 393525 0 228028 920832 0 0 0 183200 463324 0 173405 0 196264 0 261856 0 163412 118991 353297 723157 0 202624 79626 0 0 0 517508 218824 121735 361317 0 0 0 0 0 0 298842 1193167 473750 0 464142 1159230 219588 285667 213989 267423 213617 0 356457 205703 292615 0 393388 0 271086 286772 168388 534097 0 1452890 107228 261299 344706 0 621536 0 902335 1079024 452295 188625 438163 345732 294170 483256 1389340 3983048 1831542 0 880834 3119252 1560621 1567133 1264864 1383874 1405977 0 1165426 1673456 1404551 0 2271893 0 1615388 1392917 1259869 7716418 0 2882942 1662590 1441524 1701242 0 4462076 1198979 1292828 4354011 1952541 2493402 1135412 1204075 1051218 1679565 163367 728148 342246 0 501751 280671 207401 257535 93988 331231 377626 0 206308 219097 245463 0 227909 0 294753 147509 264590 529899 0 470681 0 0 311519 0 1620492 243693 540327 0 463753 0 231858 420815 201728 381758 0 0 0 0 0 0 163344 0 0 0 0 0 201022 0 0 0 0 0 0 0 0 0 0 0 0 72340 0 0 0 0 0 0 111091 0 0 0 0 0 +AAFVTK MGYG000001338_01027;MGYG000000142_03199;MGYG000000233_01112 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 9.98 0.6666666666666666 metY 1.0 - 1.0 2.5.1.49 1.0 ko:K01740 1.0 ko00270,ko01100,map00270,map01100 1.0 - 1.0 R01287,R04859 1.0 RC00020,RC02821,RC02848 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01027 0.3333333333333333 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways 1.0 K01740:metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 209825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 129782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 716328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFYEDLK MGYG000000196_04104;MGYG000001345_01383;MGYG000001378_03183 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG5523@1|root,COG5523@2|Bacteria,4NTWR@976|Bacteroidetes,2FRNK@200643|Bacteroidia,4AMPR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Protein of unknown function (DUF975) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF975 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04104 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1695888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 677102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 722687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAFYFDK MGYG000000003_01804;MGYG000003279_01060 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,2FM6J@200643|Bacteroidia,4AMTF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_2,SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_01804 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 1009934 1272765 517561 1004778 673205 1160165 694233 0 1025972 1408823 407991 1676300 747068 1052595 1655573 808717 1357050 0 1112217 1076509 1646418 908034 0 1449627 1186581 1377697 1660089 0 921969 2100800 886050 1156165 756558 0 898549 1293731 1436986 411612 0 0 0 0 0 110930 0 0 0 79623 0 0 0 63268 0 81162 0 0 0 98099 0 0 0 159662 0 0 0 0 0 0 0 0 125359 0 0 0 0 0 2322264 770804 1666197 1566762 1590414 671224 1755065 0 2057640 1502708 985001 1763717 850165 1943646 1793599 816058 1476474 0 1378593 2057436 2262282 634656 0 928866 1700064 1555539 1437865 0 1449167 2397535 954847 605972 1179690 2315974 1333461 2515541 1679176 1661488 274793 130167 196661 258762 287535 131677 246458 0 421955 333339 101819 272780 365665 366295 417693 134093 223753 0 373144 291354 281981 247998 0 240874 365385 353668 187610 0 225429 137285 305412 262153 471496 346120 349128 331314 318078 243140 0 0 0 0 0 0 0 0 94017 0 0 0 0 85852 114666 0 0 0 92436 117606 0 107934 0 132893 0 0 76235 0 94107 0 0 0 0 0 0 75905 0 0 +AAFYFDKVK MGYG000000003_01804;MGYG000003279_01060 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,2FM6J@200643|Bacteroidia,4AMTF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_2,SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_01804 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 780374 1271397 504622 1021831 802075 1181706 718904 115963 1029380 1351217 737193 1113513 823228 890720 1072577 828514 1537178 0 978515 974011 988062 989092 0 669633 1054511 830415 943101 0 854679 1485970 742991 1056884 702621 623471 543197 1260573 1126897 645617 0 0 0 0 0 0 0 0 0 0 0 0 127186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 580679 789148 446563 661875 795279 502873 317618 641603 600899 960715 561555 527967 771467 505472 641273 700415 275770 526681 0 537914 804412 898212 380766 0 388663 753968 654522 508892 0 601959 1122361 338078 78647 459368 844256 484635 1016545 543465 522011 96213 781458 91601 47277 508450 54539 366412 74604 45826 95549 61194 74733 498748 62960 90815 60827 78958 0 61108 372524 152307 147440 0 616270 149909 370194 446992 0 3002413 58456 180178 99835 56501 84010 419378 87398 146615 63881 377750 0 218332 0 0 0 0 227547 242848 0 0 294351 141661 122595 0 197442 168653 0 0 60888 0 0 0 0 0 225671 693060 0 0 116399 0 0 411458 0 37249 112390 110436 0 +AAFYIFPK MGYG000004697_00512;MGYG000002978_00471;MGYG000003266_00674;MGYG000002528_00752;MGYG000004716_00719;MGYG000004879_01333;MGYG000003683_00468;MGYG000000262_02327;MGYG000001567_00684;MGYG000003452_00958;MGYG000002492_01227;MGYG000002396_01232 domain d__Bacteria 1.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WHR7@541000|Ruminococcaceae 0.3333333333333333 186801|Clostridia 0.3333333333333333 E 0.9166666666666666 Aminotransferase class I and II 0.3333333333333333 - 0.75 - 0.75 2.6.1.2,2.6.1.66 0.6666666666666666 ko:K14260 0.6666666666666666 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 0.6666666666666666 - 0.8333333333333334 R00258,R01215 0.6666666666666666 RC00006,RC00008,RC00036 0.9166666666666666 ko00000,ko00001,ko01000,ko01007 0.75 - 1.0 - 0.9166666666666666 - 0.75 Aminotran_1_2,HTH_19,HTH_3,HTH_31 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004697_00512 0.08333333333333333 alanine transaminase. | valine--pyruvate transaminase. glutamic--pyruvic transaminase. | valine--pyruvate aminotransferase. 2-aminobutanoate acts slowly instead of alanine. | Different from EC 2.6.1.42. 2-oxoglutarate + L-alanine = L-glutamate + pyruvate. | L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine. 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Valine, leucine and isoleucine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 0.6666666666666666 K14260:alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] 0.6666666666666666 none 1.0 0 0 408146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397433 0 0 0 237016 406767 0 0 0 108380 0 0 79781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140035 0 0 0 361924 219533 0 0 0 223543 0 0 561664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467074 0 0 0 589851 367700 0 0 0 574547 0 0 207185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025876 0 0 0 172429 0 0 0 0 229913 0 0 288195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 466757 0 0 0 638807 307774 0 0 0 345334 +AAFYLFPK MGYG000002978_00471;MGYG000002528_00752;MGYG000002919_00495;MGYG000003683_00468;MGYG000000262_02327;MGYG000001698_00697;MGYG000003063_03201;MGYG000002492_01227 domain d__Bacteria 1.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WHR7@541000|Ruminococcaceae 0.375 186801|Clostridia 0.5 E 0.875 Aminotransferase class I and II 0.375 - 0.875 - 0.875 2.6.1.2,2.6.1.66 0.75 ko:K14260 0.75 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 0.75 - 0.875 R00258,R01215 0.75 RC00006,RC00008,RC00036 0.875 ko00000,ko00001,ko01000,ko01007 0.75 - 1.0 - 0.875 - 0.875 Aminotran_1_2,HTH_3 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002978_00471 0.125 alanine transaminase. | valine--pyruvate transaminase. glutamic--pyruvic transaminase. | valine--pyruvate aminotransferase. 2-aminobutanoate acts slowly instead of alanine. | Different from EC 2.6.1.42. 2-oxoglutarate + L-alanine = L-glutamate + pyruvate. | L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine. 0.75 0.75 0.75 0.75 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Valine, leucine and isoleucine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 0.75 K14260:alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2] 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277598 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAG(Gly->Asp)GVILITTK MGYG000002438_00861;MGYG000002218_02008;MGYG000000355_00074;MGYG000002478_00138;MGYG000002834_00163;MGYG000001489_04986;MGYG000003521_00292;MGYG000001666_00694;MGYG000003697_02612;MGYG000002080_00857 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 0.4 976|Bacteroidetes 1.0 P 0.9 TonB-linked outer membrane protein, SusC RagA family 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00861 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1885778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1491356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAG(Gly->Glu)ELGLTTK MGYG000000164_01271 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,25UR1@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 H 1.0 FGGY family of carbohydrate kinases, N-terminal domain 1.0 - 1.0 - 1.0 2.7.1.17 1.0 ko:K00854 1.0 ko00040,ko01100,map00040,map01100 1.0 M00014 1.0 R01639 1.0 RC00002,RC00538 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_01271 1.0 xylulokinase. Xylulose kinase. - ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+). 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Metabolic pathways 1.0 K00854:xylB, XYLB; xylulokinase [EC:2.7.1.17] 1.0 none 1.0 2780663 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3377624 0 0 0 0 3881725 3128101 0 0 0 0 0 0 0 0 3127461 0 2973362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300913 0 0 0 0 0 0 0 0 0 0 0 0 0 354343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288094 0 0 0 0 301082 212431 0 0 0 0 0 0 0 0 187305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 487071 0 0 0 0 0 530465 0 0 0 0 0 0 0 0 0 0 827428 0 +AAG(Gly->Tyr)GVILITTK MGYG000002438_00861;MGYG000002218_02008;MGYG000000355_00074;MGYG000002478_00138;MGYG000002834_00163;MGYG000001489_04986;MGYG000003521_00292;MGYG000001666_00694;MGYG000003697_02612;MGYG000002080_00857 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 0.4 976|Bacteroidetes 1.0 P 0.9 TonB-linked outer membrane protein, SusC RagA family 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00861 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2501993 2728519 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAAAAAEEEKTEFDVILAEAGATK MGYG000001300_02635 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02635 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 1603812 0 302946 0 0 9772409 333498 0 0 0 0 0 0 0 0 0 6677504 0 0 0 0 272561 0 275107 0 326991 0 0 0 0 0 0 3395064 0 0 0 302767 18566505 6870188 0 5985027 0 0 18133767 28677490 0 0 0 0 0 0 0 0 0 17313186 0 0 0 0 0 0 7734150 0 10118 0 0 0 0 0 0 8785166 0 0 0 0 179330 152316 0 79069 0 0 0 2681973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133887 0 8048956 0 0 0 0 0 0 0 0 339637 0 0 0 1697732 2601086 8539829 0 30136612 0 0 35959800 22812816 0 0 0 0 0 0 0 0 0 16356977 0 0 0 0 20436628 0 12253603 0 11254315 0 0 0 0 0 0 7186562 0 0 0 10789660 17736993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7625295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAAAALLK MGYG000001617_02059 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp900547735|m__MGYG000001617 1.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,21XZX@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Formyltetrahydrofolate synthetase 1.0 fhs 1.0 - 1.0 6.3.4.3 1.0 ko:K01938 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 1.0 M00140,M00377 1.0 R00943 1.0 RC00026,RC00111 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FTHFS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001617_02059 1.0 formate--tetrahydrofolate ligase. tetrahydrofolic formylase. In eukaryotes occurs as a trifunctional enzyme also having EC 1.5.1.5 and EC 3.5.4.9 activity. (6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6R)-10- formyltetrahydrofolate + ADP + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01938:fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAAAPAEEEKTEFDVILADVGANK MGYG000004866_01000;MGYG000000084_00772 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004866_01000 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 8838716 0 0 0 0 0 0 0 0 0 0 2546151 0 0 0 0 1255022 0 0 0 0 3347665 0 0 5615346 0 0 0 0 0 0 0 0 0 0 0 0 0 3856452 0 0 0 0 0 0 0 0 0 0 10741630 0 0 0 0 4987639 0 0 0 0 8057083 0 0 2844943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5206484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238059 0 0 0 0 9670143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 24636388 0 0 0 0 0 0 0 0 0 0 13173476 0 0 0 0 8188736 0 0 0 0 0 0 0 2081578 0 0 0 0 0 0 0 +AAGAADMSC(Carbamidomethyl)DAANVR MGYG000001300_00243 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Carboxyl transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00243 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 434146 454934 0 0 0 0 498991 0 0 0 0 0 0 0 0 0 516103 0 0 147136 0 289367 0 0 0 0 0 0 0 0 0 465488 0 0 0 0 0 0 477671 606740 0 504085 544869 0 600919 0 0 0 0 0 0 0 0 0 653506 0 0 390630 0 350010 0 0 0 0 0 0 0 0 528775 658577 0 0 0 350421 0 0 0 0 0 0 191785 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312254 676926 0 754667 717809 0 928419 0 0 0 0 0 0 0 0 0 738532 0 0 519932 0 321297 0 0 0 0 0 0 0 0 603457 1218390 0 0 0 486031 0 0 0 0 0 0 489995 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642018 619851 0 0 0 497124 +AAGAAEAAEEKDEFDVELAEVGPNK MGYG000001338_03386 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3XZZA@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03386 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294038 0 0 0 0 0 0 0 0 713053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 701460 0 0 0 0 0 0 0 0 480861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296349 0 0 0 0 0 0 0 0 376851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309243 0 0 0 0 0 0 0 0 845831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450745 0 0 0 0 0 0 0 +AAGAAEAAEEKDEFDVELAEVGPNKVK MGYG000001338_03386 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3XZZA@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03386 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 281342 0 0 782052 0 0 0 0 0 159606 0 242989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318346 1052443 0 0 0 0 0 0 0 562243 0 0 294925 0 0 0 0 0 191931 0 147510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 614521 201974 0 0 0 0 0 0 0 1343923 0 0 280525 0 0 0 0 0 279606 0 369716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550024 1073646 0 0 0 0 0 0 0 1350405 0 0 621426 0 0 0 0 0 685548 0 667235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 903409 778910 0 0 0 0 0 0 0 1352010 0 0 786961 0 0 0 0 0 505405 0 1284642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1113350 1939490 0 0 0 0 0 0 +AAGAAEAAEEKTEFDVELTEVGPNKVK MGYG000002445_02302 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp003024715|m__MGYG000002445 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002445_02302 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAAGEAAEEKDEFDVELTEVGPNKVK MGYG000000301_02336 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900541985|m__MGYG000000301 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3XZZA@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_02336 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAAGVIRPD(Asp->Ser) MGYG000000039_00617 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_H|m__MGYG000000039 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 1.0 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000039_00617 1.0 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Phosphotransferase system (PTS) 1.0 K02803:nagEb; N-acetylglucosamine PTS system EIIB component [EC:2.7.1.193]|K02804:nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 595875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4585350 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAAGVIRPDK MGYG000000022_01527;MGYG000000195_02492;MGYG000002274_00521 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 1.0 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01527 0.3333333333333333 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Phosphotransferase system (PTS) 1.0 K02803:nagEb; N-acetylglucosamine PTS system EIIB component [EC:2.7.1.193]|K02804:nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] 1.0 none 1.0 153898 0 0 0 140299 90715 234654 106355 0 79508 0 117281 0 123294 60870 144155 0 496829 0 0 115901 0 273441 154299 0 116570 0 406292 91711 94842 82579 0 153850 128235 130472 161625 0 0 605982 0 594633 0 360772 680316 217490 360620 582179 380732 0 361893 327229 549507 174538 295934 370445 3516720 0 0 214731 384762 3547292 193423 204160 313684 588846 3480070 363256 384058 240864 805486 773430 575190 517917 439532 481433 806725 1073319 0 780932 0 1086732 1195773 1321744 894640 980009 1225708 0 679372 758385 1183082 1172064 725020 1118275 3051828 0 0 762876 958575 3463698 1292128 1055055 898758 813118 3593247 1192374 1220648 978932 821241 723441 862431 941536 991898 835925 964340 0 0 0 0 0 152168 0 0 0 0 0 0 0 0 0 0 0 269769 0 0 232520 0 164115 134661 0 0 130577 330074 0 0 0 178341 0 84843 171217 163959 0 0 351499 0 492041 0 173877 307351 386572 493203 394551 353292 0 324532 339326 160942 320147 469412 324513 3807065 0 0 320630 432480 5113963 333095 259728 289391 259802 4747104 223715 186565 323387 286457 565240 363389 115973 477191 253970 409756 +AAGAAGVIRPDKTTC(Carbamidomethyl)QVIIGTK MGYG000000022_01527;MGYG000000195_02492 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 1.0 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01527 0.5 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Phosphotransferase system (PTS) 1.0 K02803:nagEb; N-acetylglucosamine PTS system EIIB component [EC:2.7.1.193]|K02804:nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212651 0 0 0 0 0 0 0 0 0 327233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 696691 0 0 0 0 570841 0 0 0 0 959801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 441170 0 0 0 0 970352 0 0 0 0 0 0 0 0 0 0 +AAGAAGVIRPGK MGYG000000140_01482 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UMGS1375|s__UMGS1375 sp900066615|m__MGYG000000140 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 1.0 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000140_01482 1.0 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Phosphotransferase system (PTS) 1.0 K02803:nagEb; N-acetylglucosamine PTS system EIIB component [EC:2.7.1.193]|K02804:nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136787 0 0 0 0 244050 0 0 0 0 102357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2953495 0 0 0 0 2164232 0 0 0 0 2008074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAAGVIRPS MGYG000001300_00059;MGYG000003899_00538;MGYG000003921_01901;MGYG000002641_02329;MGYG000001157_01521;MGYG000003937_01168;MGYG000002610_01595;MGYG000004719_01899;MGYG000003166_01772;MGYG000000084_01199;MGYG000004732_01998 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 0.9090909090909091 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 0.9090909090909091 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00059 0.09090909090909091 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Phosphotransferase system (PTS) 1.0 K02803:nagEb; N-acetylglucosamine PTS system EIIB component [EC:2.7.1.193]|K02804:nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] 1.0 none 1.0 2562984 2959722 2983834 2551600 2352356 3301349 1965050 3352730 2607111 3088989 2866458 2602366 0 3874534 4280613 2886756 2631415 13603964 4290097 3947219 2655933 2955779 6753640 2092964 3350461 2741635 2067557 7305715 2642059 2000112 2194786 0 2587881 3216156 2508801 2171207 3005343 2756895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1313738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381207 50175 604184 0 0 0 0 239677 0 0 0 0 558277 0 0 0 0 0 0 0 0 0 0 2074236 2657416 2818185 2268786 2918094 3174568 2941389 1794172 2638176 3311361 2740871 3296159 0 2188076 2316286 3222425 2736865 8655014 2513323 2798002 1475581 3197203 0 3381830 2116492 1803176 2169890 11557797 3144425 2956911 4247541 0 3473314 1092301 1712767 1909533 2231561 4401159 0 0 0 0 0 0 0 0 0 0 0 0 0 50823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAAGVIRPSK MGYG000001300_00059;MGYG000003899_00538;MGYG000002641_02329;MGYG000002610_01595;MGYG000004719_01899;MGYG000003166_01772;MGYG000003921_01901;MGYG000001157_01521;MGYG000003937_01168;MGYG000000573_01714;MGYG000000589_01770;MGYG000000084_01199;MGYG000004732_01998 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3WHW5@541000|Ruminococcaceae 0.9230769230769231 186801|Clostridia 1.0 G 1.0 Psort location CytoplasmicMembrane, score 10.00 0.9230769230769231 nagE 1.0 - 1.0 2.7.1.193 1.0 ko:K02803,ko:K02804 1.0 ko00520,ko02060,map00520,map02060 1.0 M00267 1.0 R05199 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.1.1.15,4.A.1.1.2,4.A.1.1.5,4.A.1.1.7 1.0 - 1.0 - 1.0 PTS_EIIB,PTS_EIIC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00059 0.07692307692307693 phosphotransferase. N-acetyl-D-glucosamine PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. N(pros)-phospho-L-histidyl-[protein] + N-acetyl-D-glucosamine(out) = L-histidyl-[protein] + N-acetyl-D-glucosamine 6-phosphate(in). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Phosphotransferase system (PTS) 1.0 K02803:nagEb; N-acetylglucosamine PTS system EIIB component [EC:2.7.1.193]|K02804:nagE; N-acetylglucosamine PTS system EIICBA or EIICB component [EC:2.7.1.193] 1.0 none 1.0 3038466 2578770 2320798 2402109 2202834 2726132 1885541 2625671 2155745 2557331 2028145 2356291 2633543 2021091 2220053 2731123 2295918 5345294 2085531 3138417 2659412 3229958 5476115 2171410 2850486 2291407 2276658 5204316 2897774 2565345 1504737 1587442 1975615 2388499 2732057 2050969 2024967 2342847 4769715 3514684 3312143 3884215 1987551 3951041 5304542 3022298 4825351 1213686 2398657 5263918 2716606 3938169 3725097 2453877 3853542 6572083 4880370 4583634 1797860 2688843 6754714 3539759 4625681 3312511 3326005 7128486 1269805 3028442 2991218 2185287 2985830 3925091 2317380 3728832 4682351 3045111 1697732 1521950 1584076 1760475 1453714 1482305 2077184 1474172 1311780 1475684 1776183 1943178 2223627 1709399 1597279 1711847 1478694 5562223 1493944 1656761 701372 1601075 5286905 1428029 1611113 1828197 1388687 4981754 1267774 2097856 1747146 1499609 1438019 1920502 1652060 1432108 1065968 1606331 1036008 733241 1229253 931163 1073148 778724 714988 993409 619749 1043385 936185 2080535 1388235 684444 879099 809543 1065991 2428078 773469 614957 759390 972298 987791 888465 956837 784492 794806 1837278 1120816 1130971 1408191 852450 1289181 981914 874023 889730 915558 1183571 954565 1515163 1302168 1166350 827908 898748 713018 1382741 885577 1029472 920819 4878866 728001 1146698 968403 1073812 1051221 4489404 911690 722452 872011 658004 8133682 994548 1245189 1044993 761664 5487197 963469 1584675 1276135 1068310 984277 911402 904357 1520899 800945 910876 +AAGAAIGSSRPVAETLK MGYG000002143_01991;MGYG000001300_02302;MGYG000002720_01991;MGYG000002794_01678;MGYG000000195_01164;MGYG000000233_00728;MGYG000002272_02642;MGYG000002274_01133;MGYG000002445_01436;MGYG000002545_00762;MGYG000003899_01296;MGYG000000255_01766;MGYG000002720_01954 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WRQF@541000|Ruminococcaceae 0.9230769230769231 186801|Clostridia 1.0 C 0.9230769230769231 Acyl-CoA dehydrogenase, C-terminal domain 0.9230769230769231 bcd2 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha,Rubredoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002143_01991 0.07692307692307693 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 928850 0 680185 983381 0 0 771198 0 0 0 0 597064 0 0 865599 788369 0 829711 737307 1423817 853564 544972 0 795596 1020910 0 0 0 0 0 742000 0 0 0 0 0 0 0 1191772 0 626530 1126858 0 0 919271 0 0 0 0 813945 0 0 0 893567 0 747717 494836 1315075 0 815265 0 0 1134528 0 0 0 0 0 1192754 0 0 0 0 0 0 0 0 0 1136191 0 0 0 1150629 0 0 0 0 0 0 0 3019479 0 0 960969 922018 2983499 774498 1269994 0 0 3287935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135311 109064 0 0 0 0 0 0 0 353978 0 0 0 0 0 393493 0 268553 0 336960 0 226369 0 0 0 0 0 0 547336 0 0 0 0 0 0 0 0 0 98652 120914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92081 273023 0 0 0 0 0 0 0 0 0 0 141251 0 0 0 0 +AAGAAIGSSRPVAETLR(Arg->Lys) MGYG000002994_01166 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Megasphaeraceae|g__Megasphaera|s__Megasphaera sp002319965|m__MGYG000002994 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,4H379@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF_alpha,Rubredoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002994_01166 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 777885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAAPVAAAPAAPVAPK MGYG000001300_00242 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00242 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAAVVSTGR MGYG000004558_03069;MGYG000000184_01931;MGYG000003063_03282;MGYG000000251_00123;MGYG000000213_04019;MGYG000001338_00282;MGYG000000200_01241;MGYG000000002_01111;MGYG000004526_00006 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3XYME@572511|Blautia 0.8888888888888888 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 0.8888888888888888 - 1.0 - 1.0 1.1.1.38 1.0 ko:K00027 1.0 ko00620,ko01200,ko02020,map00620,map01200,map02020 1.0 - 1.0 R00214 1.0 RC00105 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004558_03069 0.1111111111111111 malate dehydrogenase (oxaloacetate-decarboxylating). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon metabolism|Two-component system 1.0 K00027:ME2, sfcA, maeA; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] 1.0 none 1.0 1116134 1948689 1384709 500636 2572278 909927 193247 1235928 0 1072034 2033354 1499707 2295452 903982 1067809 2078056 765552 2001662 0 1594560 0 1883083 1149551 402853 1158101 625829 694378 1545556 0 840312 563521 1610181 1070004 1036964 1167675 0 625694 1368650 2041947 5697628 956296 1365742 1772978 1194368 1296639 1987515 0 865466 1528003 1051539 1848722 1091417 1028406 935589 1013706 4649924 0 1782446 0 784204 3102076 1940159 969982 1181895 1800053 4249461 0 1063749 4334528 2396533 1082860 1644210 2161711 0 1497924 1211652 1875566 5809092 1864442 2157102 812688 1520373 1478515 2493430 0 2130781 1106626 1911232 2171289 1905032 2495159 2636870 1800190 1010403 0 2509502 0 2901234 2552505 1463300 2450978 1897487 2267792 3651856 0 2604603 1494688 2682611 2595389 3011670 2709885 0 1329575 1194379 1530597 2428903 2074249 1710616 3303947 1030736 1460861 1201194 0 1280881 1309425 2615548 2182714 866607 966392 2347258 1165105 1728445 0 1328470 0 2349450 645676 2224776 790742 929002 968490 2650214 0 1807355 3481317 2239698 2764988 730328 1401026 0 1050755 2589457 945988 3312351 2944762 1426563 610313 1054005 1083871 1460932 0 1151673 3138713 2602399 0 1921677 1364146 953823 967228 221236 0 363463 0 893184 1503517 1269561 1435363 1029566 949118 1395117 0 399740 2097996 1313278 4476092 1271134 1447752 0 1011962 2284489 +AAGAD(Asp->Ala)GAAAEEKTEFDVELTEVGPNKVK MGYG000002492_00338 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00338 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 769355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGADFVGAEDLIPK MGYG000000031_00709;MGYG000000002_03534;MGYG000004718_01623;MGYG000000142_01261;MGYG000000201_02339;MGYG000000205_00361 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_00709 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 2096904 0 1121798 949431 0 1469785 0 0 0 0 2423882 0 0 0 0 0 2087307 0 0 0 1671346 1946313 0 0 2270702 0 0 0 0 0 0 0 1153441 0 2190646 0 0 597681 0 0 338758 0 0 399118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581915 0 0 0 0 0 0 0 0 369356 2154526 0 0 0 0 0 0 364735 0 0 1090041 0 0 418776 0 1072592 0 0 0 0 0 0 0 0 0 0 0 0 1018067 1524267 0 611747 1492548 0 0 0 0 1141536 0 0 2042313 1185787 1520994 0 0 0 1041707 0 0 673321 0 0 0 623715 0 0 0 0 0 0 0 0 0 0 0 0 1699061 0 0 0 0 0 0 0 0 2228266 0 0 0 0 528558 0 0 0 242997 0 0 0 0 894012 0 0 0 0 145325 0 0 0 0 0 0 0 0 0 0 692234 0 524016 114742 230921 0 0 0 0 0 0 599752 0 0 0 0 0 +AAGADFVGGDELIPK MGYG000000139_00679;MGYG000002772_00853;MGYG000000164_01129;MGYG000001374_02225;MGYG000000146_01144;MGYG000000249_00046;MGYG000000268_01636 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 0.7142857142857143 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000139_00679 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 1811669 1504386 740004 444670 1805116 2692767 2139323 1927430 2436599 2995725 1355023 0 2452051 1672510 2310564 0 1626560 473938 2014960 2202816 1985103 3262036 528886 1408162 0 1970623 0 0 2077844 0 814257 1302825 843216 1644256 1759297 1943731 1790585 784921 1695707 1549833 1685077 2036552 2046102 1375882 2415713 2274872 1487878 1512747 1572827 0 2806838 1706022 1281334 2067377 5124891 3134041 1818453 2269886 1513239 816685 1616681 1826534 0 1684374 0 2214780 2537584 0 2205547 2022945 1685112 1815972 2236320 1712035 1948958 1958361 1359373 1064318 0 977575 790368 663612 1058899 1277680 835225 1349983 963315 0 1513286 1216520 1242338 1317119 1344398 1058056 1129279 1421577 1261846 956422 1416383 838926 0 1498685 0 1679348 827929 0 858462 852435 1623923 1449785 1314875 783656 1449744 0 569765 721770 950046 476926 620148 612668 356662 829740 811046 841939 777235 0 1086253 700141 461964 952811 2638672 1311381 681238 720734 0 759923 766313 787645 0 461709 0 1746996 697948 0 564942 599292 1176812 400539 922085 425782 768954 440195 1430140 473877 369986 0 0 749210 0 500891 1215703 1121426 1075257 0 822201 238012 769363 850921 1241372 363168 429879 1491555 830381 677911 472007 996377 0 1346719 0 643853 271413 0 559806 0 300717 0 674284 851837 1253761 383716 +AAGADFVGGEDLIPK MGYG000001379_00716 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Schaedlerella|s__Schaedlerella glycyrrhizinilytica|m__MGYG000001379 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001379_00716 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2173873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGADFVGGEELIPK MGYG000002992_01641;MGYG000001186_01608;MGYG000002279_01914;MGYG000000489_01684;MGYG000003149_00722;MGYG000001688_00640;MGYG000002670_00356;MGYG000000562_01874;MGYG000000136_02022;MGYG000000187_02021;MGYG000002492_00336;MGYG000001607_01030;MGYG000001319_01772 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 0.38461538461538464 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002992_01641 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 1789608 1686642 0 1488028 0 670717 3144040 0 2061801 0 2187518 1549218 1529162 2332996 1665373 0 399236 2109444 2248454 0 0 491212 0 0 1858807 1652062 1235792 1719489 0 0 1471201 0 0 0 1433541 1375040 1306456 764813 599433 410185 0 415139 0 736931 617537 0 737683 0 246497 492257 676929 796538 0 0 439135 582303 1142665 401418 0 376910 0 0 894148 414338 243076 1250937 1613602 0 0 510236 0 633589 863078 1132014 425106 1527042 1495630 1036358 0 482035 0 691389 0 0 1141479 0 1244266 1057100 1015324 1303256 1620262 1017256 319504 1162054 2484133 1117621 0 371179 0 0 1137965 1697907 433745 1010685 0 0 1528726 1708619 0 1543052 920090 1112643 1282975 222762 359682 0 0 0 0 0 0 0 337325 0 230322 0 184655 250601 0 240458 512267 0 252583 1695797 0 0 0 0 441285 672503 1205399 266385 0 0 0 0 0 262818 245506 324548 380804 0 0 418563 0 0 0 417006 343864 0 566899 0 364140 347199 0 402031 203571 268789 0 615881 511023 307521 0 306497 0 0 0 389341 0 441704 361844 0 0 0 0 166246 328972 244875 348950 +AAGADGAAAEEKTEFDVELTEVGPNKVK MGYG000002492_00338 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00338 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282481 0 0 0 0 0 230183 0 110228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1929793 0 1990898 818970 0 0 0 0 1220014 775951 1043607 0 0 1245433 0 0 0 0 0 208564 0 489875 0 0 0 0 0 0 1242159 0 1654986 0 0 0 0 2097513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGADSADNYEK MGYG000001338_02454;MGYG000000184_00715;MGYG000000213_00629 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3XYGX@572511|Blautia 1.0 186801|Clostridia 1.0 K 1.0 Psort location Cytoplasmic, score 8.87 1.0 yebC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Transcrip_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02454 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 574293 205389 0 478879 0 0 0 0 0 577126 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 148490 0 0 0 0 0 0 1073234 0 0 201599 0 0 0 0 0 121855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 871093 0 0 0 0 0 0 0 0 745037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 966987 190662 0 398177 0 0 0 0 0 366171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732612 0 283021 0 0 0 0 156317 0 864413 551200 0 0 0 0 0 0 0 389816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 975860 0 984537 0 0 0 0 450139 +AAGADSADSYEK MGYG000000031_02633 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066205|m__MGYG000000031 1.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3XYGX@572511|Blautia 1.0 186801|Clostridia 1.0 K 1.0 Psort location Cytoplasmic, score 8.87 1.0 yebC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Transcrip_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_02633 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 350156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGADYVGAD(Methyl[D](Asp->Glu)DLIPR MGYG000004733_01323 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_01323 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 1008261 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 786184 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324290 0 0 0 0 0 0 0 0 0 0 598377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGADYVGADDLIPR MGYG000004733_01323 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_01323 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1788723 0 679626 0 0 0 0 0 0 937649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGADYVGAEDLIPR MGYG000000171_01515;MGYG000001439_02403;MGYG000002298_02666;MGYG000000212_02414;MGYG000000252_00576 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_01515 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 1392309 2610651 861345 2119397 4002257 0 1750812 0 1387664 3313987 1244739 1789047 0 1668552 2029645 1581804 2387872 1235385 1011663 1120604 4061182 1516643 1496561 1138287 992987 1023407 1854369 2395317 1372853 2449591 1195638 2181682 0 0 0 866340 2482021 356165 564691 452121 278501 343211 0 0 314354 0 533316 570924 472105 361876 0 0 0 0 0 0 437464 423033 0 872675 0 0 841093 300485 413366 2150661 339459 601416 396761 549756 0 0 0 577924 369491 1099190 1108660 2337073 625507 1217375 769833 0 1160480 0 849227 894898 1327547 1346222 0 1292114 1323322 1510966 0 817430 891447 866364 1118223 436298 696882 1049713 774856 905906 2381492 0 752312 1752029 614785 1368226 0 0 0 907502 1425661 469902 432692 801588 546162 784830 431610 0 253484 0 259969 500579 517218 719115 0 241139 934942 399877 902883 276789 528508 338746 299738 0 759815 271458 226937 666538 1082246 4558927 325625 1302355 275503 757866 0 0 0 300356 1244339 628290 558931 512522 944029 311741 754401 0 358057 0 532644 219517 350105 142133 0 467455 285681 818024 329648 647386 779631 0 614183 515133 410326 324462 385958 409276 701485 225318 695775 470118 493282 413574 0 0 0 424585 480961 +AAGADYVGDQDMITK MGYG000003891_01844 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3WH4A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_01844 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 780498 0 0 0 0 0 0 0 0 0 0 1410657 0 0 0 0 1828150 0 0 0 0 1671666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGADYVGEMDLVEK MGYG000004475_01000;MGYG000002143_01055;MGYG000004487_00621 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,2N6EQ@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004475_01000 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 935803 0 0 1545128 0 645059 0 1883933 1390508 1412733 0 0 0 0 0 0 0 0 0 0 1187361 672054 0 803176 0 1289821 0 0 0 0 0 0 0 0 795017 0 895194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 689588 0 0 0 0 0 0 0 0 0 0 0 368508 313121 0 0 0 492121 0 0 0 0 0 0 0 0 0 0 0 0 508200 0 0 406600 0 1407283 0 876899 850443 871023 0 0 0 0 0 0 0 0 0 0 613088 805852 0 637647 0 826590 0 0 0 0 0 0 0 0 1235466 0 1071519 0 0 0 0 0 0 0 0 0 0 311158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178453 0 0 0 +AAGADYVGGDELIPK MGYG000001315_01189 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01189 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 720798 2041069 0 0 636771 0 0 0 725916 1602988 1073648 0 0 0 0 0 523898 705048 848148 0 852323 315966 496074 885760 0 0 363155 0 471396 0 631790 1259418 0 0 0 0 1576190 0 1625948 1776466 0 0 1061712 0 0 0 1221505 863925 887091 0 0 0 0 0 712996 1495972 1812187 0 607063 882584 1678020 1237126 0 0 798869 0 1057033 0 1697897 1768036 0 0 0 0 1886048 0 355610 383317 0 0 312520 0 0 0 459488 415790 386831 0 0 0 0 0 459363 260452 299541 0 0 605222 0 0 0 0 919764 0 407459 0 368761 381053 0 0 0 0 409915 0 552418 1893677 0 0 847039 0 0 0 915017 694985 2287186 0 0 0 0 0 0 0 521246 0 1017043 0 582780 0 0 0 1011573 0 420553 0 599457 1994686 0 0 0 0 0 0 0 1945821 0 0 443902 0 0 0 588054 760412 702982 0 0 0 0 0 0 566931 380485 0 399944 278794 207785 625722 0 0 0 0 360613 0 421776 2429478 0 0 0 0 1954366 +AAGADYVGGEE(Glu->Asp)LIPK MGYG000001637_00078 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp900543445|m__MGYG000001637 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_00078 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1477547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2253339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGADYVGLDEYVEK MGYG000001415_02510;MGYG000003493_00379 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0081@1|root,COG0081@2|Bacteria,4NEIC@976|Bacteroidetes,2FNKI@200643|Bacteroidia,22UY1@171550|Rikenellaceae 0.5 976|Bacteroidetes 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_02510 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 821913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 941493 0 798152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAEAADNYER MGYG000000133_01488 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3XYGX@572511|Blautia 1.0 186801|Clostridia 1.0 K 1.0 Psort location Cytoplasmic, score 8.87 1.0 yebC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Transcrip_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01488 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 116603 0 0 0 0 0 0 0 0 0 0 216304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152555 0 0 365741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161162 0 0 0 0 336622 902776 0 793962 1242958 0 0 1021791 0 565407 0 0 0 1116864 1486798 473047 0 0 0 0 0 0 0 0 0 1057301 811123 0 0 0 0 0 0 1608681 0 850720 0 801942 636990 +AAGAEAAMQC(Carbamidomethyl)EQNTLNK MGYG000003266_01410;MGYG000002775_00323;MGYG000004681_00140 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG3968@1|root,COG3968@2|Bacteria,2GMA9@201174|Actinobacteria,4CUXX@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 S 1.0 Glutamate--ammonia ligase, catalytic domain protein 1.0 glnA 1.0 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003266_01410 0.3333333333333333 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Glyoxylate and dicarboxylate metabolism|Nitrogen metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Biosynthesis of amino acids|Two-component system|Necroptosis|Glutamatergic synapse|GABAergic synapse 1.0 K01915:glnA, GLUL; glutamine synthetase [EC:6.3.1.2] 1.0 none 1.0 0 750210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797584 0 0 0 0 375983 0 0 0 0 718267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAEFVGAEDLIPK MGYG000000200_03209;MGYG000002985_00771;MGYG000001338_03534;MGYG000000133_01992;MGYG000002312_03039 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000200_03209 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 1248171 0 2578514 934193 4014651 1159539 813196 1574846 1093566 0 3339510 0 2352128 1079786 1424933 1907025 0 2184308 1234528 0 1312193 1500362 1310575 513495 0 1034377 741792 0 0 0 1998342 4183713 1491593 867880 1073790 1104393 1003481 1847828 657679 0 305931 799489 0 653229 719818 881267 485965 1052568 1045484 516825 1551377 521896 632524 633950 394245 3222404 807985 0 376830 439567 1146486 0 573444 735149 820841 1976649 919215 579301 7737749 0 522468 468313 706626 0 611009 441639 1014502 6525872 1303254 1066568 833261 926521 788696 969509 761715 1005101 0 0 1733936 810382 0 1644155 960726 284753 939716 1043874 1007829 1253816 660602 878357 1098851 902911 0 963999 812155 0 1495406 0 1886566 1101875 1052921 776589 890027 1118612 940303 0 0 860249 0 1064249 942960 793530 840138 1024931 0 0 0 868130 840671 0 988019 823719 659251 1064718 855747 1101332 500955 1295286 784161 753598 847167 1431417 0 883653 7082895 0 0 454703 333819 925962 756394 2130475 5813280 13949750 8550876 9166833 2450410 3353253 7503721 5130903 3825751 7711872 7205817 5290779 5930601 11451546 5738413 5386610 5368734 985275 5517581 1964487 6503617 4817548 1568511 4676288 6064865 4965144 7489802 2151724 10518315 1519100 9176207 14731550 11977472 5585506 4232391 6660803 3907261 5585724 +AAGAEFVGAEE(Glu->Asp)LIPK MGYG000002528_01114;MGYG000004296_01660;MGYG000000262_02173;MGYG000000028_00271;MGYG000000050_01365 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 0.6 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01114 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1469658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1770526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAEFVGAEELIPK MGYG000002528_01114;MGYG000004296_01660;MGYG000000262_02173;MGYG000000028_00271;MGYG000000050_01365 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 0.6 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01114 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 639039 0 0 0 0 0 0 0 0 0 0 1741464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 542397 0 0 0 749601 889581 1571588 0 0 0 1562285 781484 0 562863 0 0 0 0 0 0 0 0 4632029 1023942 0 0 3283316 750501 717382 460846 1479674 0 1171215 0 589159 966228 0 501694 0 761314 702503 0 6045921 0 1550498 0 0 733281 0 3817164 0 796613 3916112 0 3290558 868753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 482591 0 0 0 666404 0 845919 0 0 0 0 2299337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1927083 0 0 0 0 0 0 0 158038 0 0 0 0 0 0 0 1483395 828143 0 0 0 0 1123747 0 0 0 0 476058 0 0 0 0 0 +AAGAEFVGAEELVPK MGYG000003335_00786 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__GCA-900066135|s__GCA-900066135 sp900543575|m__MGYG000003335 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003335_00786 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 504469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAEFVGG(Gly->Ala)DELIPK MGYG000000095_03286 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__GCA-900066755|s__GCA-900066755 sp902363085|m__MGYG000000095 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,25VN3@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000095_03286 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2181435 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAEGGAEEKDEFDVELTEVGGAK MGYG000002528_01112;MGYG000000028_00269 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,36IQP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01112 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 299281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342627 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 678129 0 391542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375313 0 145769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAELLC(Carbamidomethyl)ETTLEK MGYG000001338_03411 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3WHNU@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GHMP kinase family 1.0 galK 1.0 - 1.0 2.7.1.6 1.0 ko:K00849 1.0 ko00052,ko00520,ko01100,map00052,map00520,map01100 1.0 M00554,M00632 1.0 R01092 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03411 1.0 galactokinase. - Part of the Leloir pathway for galactose metabolism.-!-The enzymes from mammals and from the bacterium Escherichia coli have no activity with N-acetyl-alpha-D-galactosamine. alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+). 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K00849:galK; galactokinase [EC:2.7.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1822742 0 0 0 0 0 0 0 +AAGAELVGM(Oxidation)EDLAEQIK MGYG000002494_02478;MGYG000002477_00980 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,3WVKV@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02478 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAELVGMEDLADQIK MGYG000002506_03690;MGYG000003390_01040;MGYG000000235_04431 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,3WVKV@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_03690 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 2782787 2821050 3050548 0 1110966 2724761 2719041 0 2385325 2377113 1445552 1978077 1743363 0 0 0 2273658 0 2850752 2126708 1335044 3216587 0 3273788 1965158 1841703 0 0 1815690 0 0 0 2962751 3071537 2444903 2481873 2168501 3041157 0 1262267 937641 0 0 0 0 0 3258286 0 903322 1074206 1233888 0 0 0 193742 0 915784 1826369 1838984 0 0 2133264 0 1222062 0 0 569192 0 0 0 0 3321729 5615894 0 0 0 1760315 963346 9885702 0 6871367 8567110 7436004 0 17844828 2163321 898143 7607703 2004211 0 0 0 7063225 0 0 2218586 7588561 9923701 0 30774370 1673909 17416831 0 0 0 0 0 0 1624225 1793885 13744949 11758687 10636765 11919253 16795136 8561371 15833148 0 0 15744295 25027397 0 8905855 24377881 2171344 8079846 14101486 0 0 0 15109577 0 16676100 16532664 12393990 33014560 0 12814157 14620060 9780950 0 0 18670901 0 0 0 6961105 32166231 9882975 23365071 0 14730657 5503082 324043 0 0 0 3267425 172058 0 4105879 185697 0 1035462 593332 0 0 0 277445 0 0 0 0 0 0 0 2837708 249074 0 0 1055238 0 0 0 63664 0 0 5410204 0 0 +AAGAELVGMEDLADQIKK MGYG000002506_03690 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,3WVKV@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_03690 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254347 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAELVGMEDLAEQIKK MGYG000002494_02478;MGYG000002477_00980 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1MUE6@1224|Proteobacteria,1RMDW@1236|Gammaproteobacteria,3WVKV@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02478 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 267025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 648419 728166 0 0 0 1384924 0 0 0 0 0 0 0 394467 0 0 532283 0 0 0 0 1732961 0 1112767 1170081 509694 0 0 1027715 0 0 0 0 0 0 0 264957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437335 0 0 0 175241 0 0 0 0 0 0 0 102804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAETDKVSPLLLPNYAR MGYG000000002_00154 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A faecis|m__MGYG000000002 1.0 COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WHXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 FAD binding domain 1.0 - 1.0 - 1.0 1.3.5.1,1.3.5.4,1.3.99.33 1.0 ko:K00239,ko:K00244,ko:K17363 1.0 ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 1.0 M00009,M00011,M00149,M00150,M00173,M00374,M00376 1.0 R02164,R10330 1.0 RC00045,RC00669 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,FMN_bind,FMN_red 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000002_00154 1.0 succinate dehydrogenase. | urocanate reductase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. | The enzyme functions as part of an anaerobic electron transfer chain that utilizes urocanate as the terminal electron acceptor.-!-The activity has been demonstrated with the artificial donor reduced methyl viologen. a quinone + succinate = a quinol + fumarate. | A + dihydrourocanate = AH2 + urocanate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Histidine metabolism|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Two-component system|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]|K00244:frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]|K17363:urdA; urocanate reductase [EC:1.3.99.33] 1.0 none 1.0 0 0 0 0 0 626312 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 738705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176729 0 207059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAEYIVVPSMR MGYG000000003_01284 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG1082@1|root,COG1082@2|Bacteria,4NJ3Z@976|Bacteroidetes,2FNWR@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 COG COG1082 Sugar phosphate isomerases epimerases 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_01284 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 589893 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443322 0 0 +AAGAEYVGAEELIPK MGYG000000080_02021;MGYG000004735_02574 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_02021 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAF(Nitro)AQLLAR MGYG000003022_00729;MGYG000003352_01558 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,1KJ2C@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003022_00729 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1054341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAFAQLLAR MGYG000003022_00729;MGYG000003352_01558 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,1KJ2C@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003022_00729 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 0 0 0 0 0 0 0 102193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 951878 568378 0 0 0 646497 1046914 0 755793 0 0 0 0 0 0 0 0 569894 0 0 0 0 0 0 0 0 0 0 0 853841 640258 587852 0 1341305 0 0 604140 0 1954689 0 0 0 0 88488 787489 0 413323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553138 0 0 0 705696 0 0 111599 0 0 0 0 0 0 0 0 0 90453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405961 395152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAFAQLVAR MGYG000001410_00779;MGYG000004694_00685;MGYG000003170_00053 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella 1.0 COG0090@1|root,COG0090@2|Bacteria,1MVTD@1224|Proteobacteria,2VHSD@28216|Betaproteobacteria,4PQ90@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001410_00779 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 0 0 0 0 0 0 0 0 445575 0 0 0 328113 0 230925 287296 0 0 0 655631 0 0 0 0 0 0 0 0 0 329010 0 0 0 0 639567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109212 0 0 376171 0 0 0 0 0 0 0 0 0 0 0 0 0 443140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1128829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 747573 0 0 0 789422 0 602740 891000 0 0 0 967241 0 0 0 0 0 0 0 0 0 984572 0 0 0 0 1888191 0 0 0 +AAGAGAAAAEEKTEFDVELTEVGPNKVK MGYG000000198_05826 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_05826 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 278455 0 0 0 0 0 0 0 0 0 462940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766367 0 0 0 0 0 0 0 0 0 783003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 149927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180984 0 0 0 0 0 0 0 0 0 356276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272067 0 0 0 0 0 0 0 0 +AAGAGAAAEEEKTEFDVELTEGSGVPVIK MGYG000001319_01770 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,4BZC5@830|Butyrivibrio 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001319_01770 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1854409 0 0 0 0 1801698 0 0 0 0 2148973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAGAAAEEEKTEFDVELTEVGPNKVK MGYG000000255_02155 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,2207U@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_02155 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 417892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 674864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122471 0 0 0 0 +AAGAGAAAILTK MGYG000000212_00918 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Myosin-crossreactive antigen 1.0 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_00918 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 - 1.0 K10254:ohyA, sph; oleate hydratase [EC:4.2.1.53] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 814931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAGDGAAAEEK MGYG000002517_00194;MGYG000000245_03674 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00194 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 69003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406875 0 0 0 333885 0 0 0 0 0 0 340210 0 0 0 0 0 0 0 0 0 468082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 198247 0 0 0 0 0 0 282932 0 0 0 0 0 0 0 0 0 320986 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAGDGAAAEEKTEFDVELTEVGPNKVK MGYG000002517_00194;MGYG000000245_03674 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00194 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 301615 0 0 0 0 399100 0 188121 494164 212841 0 0 211201 210778 176116 0 0 0 0 0 0 0 0 233713 491438 417441 363322 0 0 0 0 0 0 217263 240850 239118 291850 0 288175 0 0 0 0 525018 0 477732 0 249828 0 0 227453 575625 0 0 0 0 0 0 0 0 0 0 0 368871 0 0 0 0 0 0 0 518758 211656 0 573758 0 0 0 0 0 0 0 0 203154 171554 247826 0 0 108922 0 0 0 0 0 0 0 0 0 0 0 183082 456378 0 0 0 0 0 0 0 0 491472 267597 299834 0 1087239 0 0 0 0 689978 0 1317318 1303891 685694 0 0 298189 1070855 1208841 0 0 0 0 0 0 365526 0 339919 1312199 1449199 1198130 0 0 0 0 0 0 1560158 1539184 1191981 1431056 0 773173 0 0 0 0 881644 0 160113 603273 1080569 0 0 1308232 717927 947599 0 0 0 0 0 0 629075 0 743810 857304 642354 825981 0 0 0 0 0 0 683627 1003781 207298 681215 0 +AAGAGVAALAAGSHK MGYG000002517_00467 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Myosin-crossreactive antigen 1.0 - 1.0 - 1.0 4.2.1.53 1.0 ko:K10254 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 MCRA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00467 1.0 oleate hydratase. - Acts on a number of 10-hydroxy acids. (R)-10-hydroxyoctadecanoate = (9Z)-octadecenoate + H2O. 1.0 1.0 1.0 1.0 - 1.0 K10254:ohyA, sph; oleate hydratase [EC:4.2.1.53] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAGVIHK MGYG000002469_01020;MGYG000003683_00636 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,4D18U@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002469_01020 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02968:RP-S20, rpsT; small subunit ribosomal protein S20 1.0 none 1.0 0 187181 559377 0 0 124565 0 0 0 0 0 0 0 0 0 0 0 297402 0 0 0 493577 373897 411829 0 0 0 383785 0 0 428495 0 693743 0 0 0 0 496281 0 1603469 2250277 0 0 3251941 0 0 0 0 0 0 0 0 0 0 0 4950938 0 0 0 1694835 3062341 6468713 0 0 0 7092370 0 0 4674841 0 1544463 0 0 0 0 2126606 0 884564 443503 0 0 142088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545651 141357 216253 0 0 0 666837 0 0 149466 0 1032546 0 0 0 0 436391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 66711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGANKIAVIK MGYG000001632_01220 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-170|s__|m__MGYG000001632 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,36IQP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001632_01220 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1863623 0 +AAGANKLAIVK MGYG000000044_01728;MGYG000002438_02328 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000044_01728 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 157880 0 142415 146570 223504 144532 75511 0 0 73862 0 151256 187595 0 0 176703 94663 0 68358 141658 263666 131751 0 154515 0 141269 0 0 80575 180693 177211 241228 246898 0 0 112779 173692 0 161347 0 0 0 374914 38523 0 0 0 154893 0 127473 257983 0 0 239816 98342 0 0 0 238505 67717 0 51797 0 130369 0 0 137270 0 73865 304761 0 0 0 121974 0 164933 0 0 119433 0 278636 168002 75352 0 0 87012 0 151857 90280 0 0 170429 114330 0 158985 63342 202370 195374 0 150086 0 65119 0 0 192228 73493 289638 385454 226438 0 0 150225 0 113036 62007 0 0 0 0 0 0 0 0 0 0 281966 0 0 0 79666 0 0 0 0 364140 0 0 0 0 0 0 0 0 84353 0 61924 0 0 0 70984 191626 0 930809 0 1475635 1680234 2877658 1538301 833151 0 0 2297120 0 3800058 2203805 0 0 1494670 1588484 0 781418 827407 1871591 826569 0 974825 0 1567933 0 0 952210 1767947 1514138 2328050 870490 0 0 1592628 0 1658896 +AAGANKVAVIK MGYG000002506_03692 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,3XPRN@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_03692 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 981721 1279053 0 0 1364483 0 1023171 0 0 0 0 0 0 0 0 814094 0 0 977680 0 1770261 0 1336829 0 0 0 0 0 0 0 1104239 1202479 0 0 0 0 1437127 0 450323 226334 0 0 414398 0 132525 0 0 0 0 0 0 0 0 282660 0 0 114044 0 874941 0 335080 0 0 0 0 0 0 0 326222 251375 0 0 0 0 347831 0 1438027 577197 0 0 1051282 0 927889 0 0 0 0 0 0 0 0 283347 0 0 240472 0 958927 0 882301 0 0 0 0 0 0 0 900294 494500 0 0 0 0 342430 0 239382 411574 0 0 603521 0 1268226 0 0 0 0 0 0 0 0 340308 0 0 157300 0 797539 0 217757 0 0 0 0 0 0 0 855439 686968 0 0 0 0 243387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGASAQVLGQEGK MGYG000004789_00688 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Lactobacillales|f__Streptococcaceae|g__Streptococcus|s__Streptococcus sp001556435|m__MGYG000004789 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli 1.0 91061|Bacilli 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004789_00688 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 748873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGASLLR MGYG000001300_02032 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,3WG9J@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 synthase 1.0 aroF 1.0 - 1.0 2.5.1.54 1.0 ko:K03856 1.0 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 1.0 M00022 1.0 R01826 1.0 RC00435 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAHP_synth_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02032 1.0 3-deoxy-7-phosphoheptulonate synthase. phospho-2-oxo-3-deoxyheptonate aldolase. Formerly EC 4.1.2.15. D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2- dehydro-3-deoxy-D-arabino-heptonate + phosphate. 1.0 1.0 1.0 1.0 Phenylalanine, tyrosine and tryptophan biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K03856:AROA2, aroA; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3533144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGATSFDQYK MGYG000001313_02506 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_02506 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K01802:E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]|K03770:ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 32682217 0 0 0 0 0 0 0 0 0 0 0 0 34997357 0 0 0 0 30841112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGATTANITQAIEQMR MGYG000002506_02112;MGYG000002515_00455 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0542@1|root,COG0542@2|Bacteria,1MURH@1224|Proteobacteria,1RN55@1236|Gammaproteobacteria,3XN3I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 1.0 - 1.0 ko:K03695 1.0 ko04213,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 MGYG000002506_02112 0.5 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - multiple species 1.0 K03695:clpB; ATP-dependent Clp protease ATP-binding subunit ClpB 1.0 none 1.0 665089 716248 0 0 0 1028073 905654 1211798 758457 1278253 0 0 0 0 0 0 0 0 0 575873 598980 948774 0 965563 511348 347812 600338 0 644720 863487 0 0 0 750412 836943 0 548948 0 0 0 0 0 0 374242 66886 0 0 79219 0 0 0 0 0 0 0 0 0 0 0 657341 0 602444 66338 77579 0 0 0 0 0 0 0 0 152678 0 0 0 515267 0 0 0 0 992071 394754 324665 290031 362690 0 0 0 0 0 0 0 0 0 0 229882 356748 0 521932 509972 563230 278397 0 210574 218167 0 0 0 377140 444817 0 550724 0 0 0 0 0 0 0 0 261766 0 0 0 0 0 0 0 0 0 0 0 157310 0 0 0 0 0 0 0 0 0 0 0 0 0 278353 95023 0 207678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGATTFDQYK MGYG000003681_00916 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_00916 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K01802:E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]|K03770:ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692880 0 0 0 0 0 639926 770869 0 0 0 0 0 1060878 0 0 780696 0 0 0 0 0 0 0 0 732650 0 0 0 0 0 0 0 0 994394 0 653583 0 0 0 0 0 0 0 384401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGATTVSAPMPGK MGYG000001365_01216 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A|s__Phascolarctobacterium_A succinatutens|m__MGYG000001365 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001365_01216 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 513380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 444150 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308427 0 0 0 0 0 0 0 547966 0 575214 810792 0 0 0 0 0 0 0 0 0 0 0 678604 0 0 0 1069926 839345 804554 0 0 0 682230 1133931 0 818199 0 474712 0 0 0 0 619586 +AAGATVVSVTHAAGSALTK MGYG000000195_03246;MGYG000002040_01608;MGYG000002619_01556;MGYG000001255_01728;MGYG000002545_01644;MGYG000002610_01474;MGYG000003166_02168 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG2222@1|root,COG2222@2|Bacteria,1TRTA@1239|Firmicutes,24BGB@186801|Clostridia,3WJ2A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 M 1.0 SIS domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SIS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000195_03246 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546800 528649 0 0 0 0 0 0 0 0 0 0 0 0 0 1341882 0 0 0 0 1058288 0 712626 0 0 853216 0 0 0 0 625736 0 0 0 0 686122 0 0 311786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1947558 0 0 0 0 2816640 0 0 0 0 2324499 0 0 0 0 407396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAVDGSDEK MGYG000003683_01237;MGYG000000756_00019 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4CYVV@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGE-sulfatase,Glucosamine_iso,PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01237 0.5 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 89535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109008 0 0 566702 0 294381 395029 0 0 0 313831 348191 0 882588 0 0 492903 0 1050674 0 0 0 183693 1009195 769400 0 0 374705 2261900 385003 0 1850181 0 212155 300755 166108 0 0 407272 0 0 141136 0 0 0 0 0 0 106511 0 0 120680 0 0 161732 0 0 0 0 0 0 100004 0 0 0 262952 67464 0 0 0 0 314964 280771 302811 0 0 84736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94379 0 0 46581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAVDGSDEKNAEAIKK MGYG000003683_01237 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0166@1|root,COG0166@2|Bacteria,2GJG0@201174|Actinobacteria,4CYVV@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGE-sulfatase,Glucosamine_iso,PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01237 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 254741 0 199507 0 0 0 0 0 0 0 325897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87806 0 0 65856 0 145910 0 0 0 0 178295 0 393463 448801 0 361808 420329 0 0 0 0 0 0 1156866 0 0 0 0 1467678 0 0 0 299720 441557 813114 0 0 0 1019253 0 0 867229 0 428101 313846 0 0 0 427724 0 431666 217676 0 0 0 0 0 0 0 0 0 303542 0 0 0 0 0 0 0 0 206740 95123 0 0 0 0 236063 0 0 0 0 604058 383850 0 0 0 247697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGAVLMNMETK MGYG000000089_01614 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG1053@1|root,COG1053@2|Bacteria,2J6FD@203691|Spirochaetes 1.0 203691|Spirochaetes 1.0 C 1.0 PFAM fumarate reductase succinate dehydrogenase flavoprotein 1.0 - 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000089_01614 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2381439 0 0 0 0 2804067 0 0 0 0 1825488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545593 0 0 0 0 312491 0 0 0 0 565936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1318237 0 0 0 0 802791 0 0 0 0 1519523 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1277549 0 0 0 0 397294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 540740 0 0 0 0 403078 0 0 0 0 1076826 0 0 0 0 0 0 0 0 0 0 +AAGC(Carbamidomethyl)PDLNIQIK MGYG000000074_00674;MGYG000000053_01331 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,2FNGS@200643|Bacteroidia,22UCD@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin 1.0 ribH 1.0 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 2.5.1.78 1.0 ko:K00794 1.0 ko00740,ko01100,ko01110,map00740,map01100,map01110 1.0 M00125 1.0 R04457 1.0 RC00960 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DMRL_synthase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00674 0.5 6,7-dimethyl-8-ribityllumazine synthase. lumazine synthase. Involved in riboflavin biosynthesis. (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate. 1.0 1.0 1.0 1.0 Riboflavin metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00794:ribH, RIB4; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] 1.0 none 1.0 260652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368124 0 0 0 0 0 0 0 0 0 0 0 415950 0 0 0 241650 0 0 0 0 0 0 0 0 0 0 0 214658 188496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1041064 0 0 0 0 1002759 0 821851 0 0 0 0 0 750139 0 0 0 0 0 1849959 0 676329 0 709455 0 1112521 780557 0 0 1346681 672732 0 0 0 0 764096 1179922 0 +AAGC(Carbamidomethyl)PDMNIQVK MGYG000000003_00525 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG0054@1|root,COG0054@2|Bacteria,4NNUC@976|Bacteroidetes,2FNGS@200643|Bacteroidia,22UCD@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin 1.0 ribH 1.0 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.0 2.5.1.78 1.0 ko:K00794 1.0 ko00740,ko01100,ko01110,map00740,map01100,map01110 1.0 M00125 1.0 R04457 1.0 RC00960 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DMRL_synthase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_00525 1.0 6,7-dimethyl-8-ribityllumazine synthase. lumazine synthase. Involved in riboflavin biosynthesis. (2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate. 1.0 1.0 1.0 1.0 Riboflavin metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00794:ribH, RIB4; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 972164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGC(Carbamidomethyl)TAIIALGGGSPMDVAK MGYG000002448_00117 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Evtepia|s__Evtepia gabavorous|m__MGYG000002448 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WGYX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 - 1.0 - 1.0 1.1.1.1 1.0 ko:K13954 1.0 ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00623,R00754,R04880,R05233,R05234,R06917,R06927 1.0 RC00050,RC00088,RC00099,RC00116,RC00649 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002448_00117 1.0 alcohol dehydrogenase. aldehyde reductase. Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K13954:yiaY; alcohol dehydrogenase [EC:1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 823631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGC(Carbamidomethyl)TALIALGGGSPMDVAK MGYG000004736_00489 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Evtepia|s__Evtepia sp004554585|m__MGYG000004736 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WGYX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 - 1.0 - 1.0 1.1.1.1 1.0 ko:K13954 1.0 ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00623,R00754,R04880,R05233,R05234,R06917,R06927 1.0 RC00050,RC00088,RC00099,RC00116,RC00649 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004736_00489 1.0 alcohol dehydrogenase. aldehyde reductase. Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K13954:yiaY; alcohol dehydrogenase [EC:1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 544034 0 383896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 759367 0 567774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGDAAAAAK MGYG000002478_01081 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01081 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 679529 1773203 0 0 646408 0 0 0 0 429095 0 0 234026 641173 0 0 279201 0 0 0 612747 0 0 0 444353 319743 0 0 0 457537 0 0 0 0 494316 0 352008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 48283 0 0 0 0 0 0 0 0 0 0 0 0 0 670473 70432 0 0 0 0 0 0 0 91433 0 0 58994 44085 0 0 166719 0 0 0 0 0 0 0 0 239935 0 0 0 0 0 0 0 0 61457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGDAAAAAKAAADKAVADAKAEAIK MGYG000002478_01081 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01081 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGDAYVTQLGIDMAER MGYG000000099_02268 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,248K3@186801|Clostridia,26BE6@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Peptidase family C69 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,FIVAR,Peptidase_C69,SLH,fn3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_02268 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 906424 0 0 452944 0 0 0 0 0 0 0 0 0 0 209623 961432 0 0 512672 0 0 0 0 0 453155 412170 0 0 0 0 0 0 0 0 0 609417 783560 0 751980 0 0 919722 0 0 0 0 1030995 0 0 0 0 0 1289083 1177521 0 0 830208 0 0 0 802896 833728 887409 0 0 274682 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385778 0 0 0 0 0 0 0 0 343298 344169 328491 0 +AAGDEETFAAK MGYG000002919_01993;MGYG000001642_01511 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4CU83@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 NADH flavin oxidoreductase 1.0 - 1.0 - 1.0 1.3.1.31,1.3.1.34 1.0 ko:K00219,ko:K10797 1.0 ko00360,ko01120,map00360,map01120 1.0 - 1.0 R02252 1.0 RC00669 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Oxidored_FMN,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002919_01993 0.5 2-enoate reductase. | 2,4-dienoyl-CoA reductase [(2E)-enoyl-CoA-producing]. enoate reductase. | 4-enoyl-CoA reductase (NADPH). Acts, in the reverse direction, on a wide range of alkyl and aryl alphabeta-unsaturated carboxylate ions; 2-butenoate was the best substrate tested. | This bacterial enzyme catalyzes the reduction of either (2E,4E)-2,4- dienoyl-CoA or (2E,4Z)-2,4-dienoyl-CoA to (2E)-2-enoyl-CoA.-!-The enzyme from Escherichia coli contains FAD, FMN, and an [4Fe-4S] iron sulfur cluster. cf. EC 1.3.1.124. butanoate + NAD(+) = (2E)-2-butenoate + H(+) + NADH. | (1) a 4,5-saturated-(2E)-enoyl-CoA + NADP(+) = a (2E,4E)-dienoyl-CoA + H(+) + NADPH. (2) a (2E,4Z)-dienoyl-CoA + H(+) + NADPH = a 4,5-saturated-(2E)-enoyl-CoA + NADP(+). 1.0 1.0 1.0 1.0 Phenylalanine metabolism|Microbial metabolism in diverse environments 1.0 K00219:fadH; 2,4-dienoyl-CoA reductase (NADPH2) [EC:1.3.1.34]|K10797:enr; 2-enoate reductase [EC:1.3.1.31] 1.0 none 1.0 0 1102732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1483317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGDGAAAAEEKDEFDVELVSAGASK MGYG000000164_01127 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,27VNP@189330|Dorea 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_01127 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 609176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGDGIGFNAAENKYEDMMK MGYG000001060_01600 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister hominis|m__MGYG000001060 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4H29X@909932|Negativicutes 1.0 909932|Negativicutes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 - 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000001060_01600 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2227012 0 0 0 0 2260224 0 0 0 0 1755162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGDSYGQHPVGTGPYK MGYG000002485_01346 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0747@1|root,COG0747@2|Bacteria,3785F@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_01346 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1542685 1855893 2403271 0 1874795 3059029 1526538 0 0 3814586 3124099 1564727 2283581 1779080 0 3076443 1448334 0 1534180 1394638 1212162 3641624 0 2471007 0 1614502 1853174 0 0 1462784 2345590 3147226 2603619 1628856 0 1341459 1576617 2520451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGDTPYIVGEIK MGYG000002517_00839 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Phosphoribosylformylglycinamidine cyclo-ligase 1.0 purM 1.0 - 1.0 6.3.3.1 1.0 ko:K01933 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04208 1.0 RC01100 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000002517_00839 1.0 phosphoribosylformylglycinamidine cyclo-ligase. phosphoribosyl-aminoimidazole synthetase. - 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino- 1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01933:purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277375 0 0 0 0 0 0 0 0 0 453123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 631225 0 0 0 0 0 0 0 0 0 579960 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGDTPYIVGHMEAGEK MGYG000002528_00489;MGYG000000028_01458 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,27VFI@189330|Dorea 1.0 186801|Clostridia 1.0 F 1.0 AIR synthase related protein, N-terminal domain 1.0 purM 1.0 - 1.0 6.3.3.1 1.0 ko:K01933 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04208 1.0 RC01100 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000002528_00489 0.5 phosphoribosylformylglycinamidine cyclo-ligase. phosphoribosyl-aminoimidazole synthetase. - 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino- 1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01933:purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429914 0 0 0 0 0 0 0 0 0 468774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGDTPYVVGR MGYG000000184_02206;MGYG000001338_00068 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,27VFI@189330|Dorea 1.0 186801|Clostridia 1.0 F 1.0 AIR synthase related protein, N-terminal domain 1.0 purM 1.0 - 1.0 6.3.3.1 1.0 ko:K01933 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04208 1.0 RC01100 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000000184_02206 0.5 phosphoribosylformylglycinamidine cyclo-ligase. phosphoribosyl-aminoimidazole synthetase. - 2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino- 1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01933:purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1] 1.0 none 1.0 0 1480001 0 0 1710359 0 0 0 0 0 0 0 0 0 0 0 0 770180 0 0 0 0 541195 0 0 0 0 767600 0 0 380901 1500922 0 0 0 0 0 0 0 3215040 0 0 850496 0 0 0 0 0 0 0 0 0 0 0 0 914262 0 0 0 0 534489 0 0 0 0 886592 0 0 2934895 1390606 0 0 0 0 0 0 0 2884664 0 0 455210 0 0 0 0 0 0 0 0 0 0 0 0 1205660 0 0 0 0 514956 0 0 0 0 2201026 0 0 418973 2244917 0 0 0 0 0 0 0 3628829 0 0 1925334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721665 0 0 2641882 2418380 0 0 0 0 0 0 0 1570292 0 0 555094 0 0 0 0 0 0 0 0 0 0 0 0 413588 0 0 0 0 0 0 0 0 0 376284 0 0 1264523 1484376 0 0 0 0 0 0 +AAGDVPTQEIMAASDKLK MGYG000001292_01832 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001292_01832 1.0 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K01621:xfp, xpk; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1927370 0 0 0 0 1281521 0 0 0 0 2268716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGE(Glu->Asp)AATAVAK MGYG000000196_05075 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 2AFRI@1|root,315TH@2|Bacteria,4PK03@976|Bacteroidetes,2FTKM@200643|Bacteroidia,4ARI1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_05075 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 375139 0 428110 0 432526 182843 408689 356551 0 301494 484242 0 387120 0 310569 165390 0 0 353016 161632 0 292637 0 373424 0 405091 355523 0 0 0 0 629154 520650 0 0 289801 357662 467212 142558 0 318993 241720 228622 0 217811 321030 0 289458 204597 0 216720 0 89262 211432 198948 0 0 0 0 214277 0 0 0 0 153465 0 198231 276922 0 173003 599144 126552 0 0 0 206264 179388 0 260115 322167 161907 239169 233638 214414 0 237061 200067 0 400108 0 288157 261992 165555 0 552979 321651 0 370830 0 159200 0 146284 366921 0 187780 436253 0 75948 216986 227451 0 406266 143820 139963 0 0 0 159549 215748 151418 121437 0 0 0 230974 0 129352 0 0 0 0 0 201693 0 0 0 0 681870 0 146930 0 0 223854 262480 0 0 0 0 0 0 0 0 15098807 0 7191981 15325879 16120095 9536887 14639485 20834830 0 14129029 10607408 0 18296899 0 13738918 7539526 8101499 0 8572416 18982058 0 7146885 0 12311407 0 17750589 13759241 0 11009019 16694867 0 12776738 7550552 15664043 0 14341623 20109999 12609454 +AAGEAAQLMAK MGYG000000377_02054 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__UMGS1766|s__|m__MGYG000000377 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,267V8@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000377_02054 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2415748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGEAFEK MGYG000001338_00105;MGYG000000200_01610;MGYG000000184_02260 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3XYP0@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Galactose mutarotase-like 1.0 - 1.0 - 1.0 3.2.1.20 1.0 ko:K01187 1.0 ko00052,ko00500,ko01100,map00052,map00500,map01100 1.0 - 1.0 R00028,R00801,R00802,R06087,R06088 1.0 RC00028,RC00049,RC00077 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH31 1.0 - 1.0 DUF5110,Gal_mutarotas_2,Glyco_hydro_31 1.0 3.2.1.20 1.0 GH31 1.0 GH31 1.0 GH31 1.0 MGYG000001338_00105 0.3333333333333333 alpha-glucosidase. maltase-glucoamylase. Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.-!-The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links. Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. 1.0 1.0 1.0 1.0 Galactose metabolism|Starch and sucrose metabolism|Metabolic pathways 1.0 K01187:malZ; alpha-glucosidase [EC:3.2.1.20] 1.0 none 1.0 0 227299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 560902 0 0 0 0 0 0 0 1474400 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 891670 0 0 0 0 0 0 0 1817356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2262684 0 0 0 0 0 0 0 1861253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1812158 0 0 0 0 0 0 0 2468936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4222028 0 0 0 0 0 0 +AAGEALWTLR MGYG000000133_00022 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3XYWB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner 1.0 valS 1.0 - 1.0 6.1.1.9 1.0 ko:K01873 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03665 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 GH5_11 1.0 MGYG000000133_00022 1.0 valine--tRNA ligase. valyl-tRNA synthetase. - ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01873:VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9] 1.0 none 1.0 0 0 98744 119851 0 227946 538825 0 0 146024 0 96448 0 309623 0 380204 0 0 200879 0 344493 338586 0 481723 103803 0 128663 0 101773 0 0 0 0 0 0 285988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183112 0 0 0 0 0 0 0 0 0 0 0 0 242030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 617618 947300 0 477346 1099102 0 0 821204 0 810098 0 1307299 0 727047 0 0 673922 0 1041276 696479 0 488245 736697 0 896351 0 1432865 0 0 0 1304803 0 0 670957 0 430720 +AAGEGSTYWDDIR MGYG000001310_02117 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG0366@1|root,COG4733@1|root,COG5492@1|root,COG0366@2|Bacteria,COG4733@2|Bacteria,COG5492@2|Bacteria,1UVIA@1239|Firmicutes,25KIT@186801|Clostridia,3WMI9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 N 1.0 Bacterial Ig-like domain 2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Big_2,CarboxypepD_reg,F5_F8_type_C,Flg_new,Glyco_hyd_101C,Glyco_hydro_101,Lyase_8,Lyase_8_C,Lyase_8_N,SLH,fn3 1.0 3.2.1.97 1.0 GH101 1.0 CBM32+GH101 1.0 GH101 1.0 MGYG000001310_02117 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGET(Thr->Ala)LWTLR MGYG000000301_00138 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900541985|m__MGYG000000301 1.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3XYWB@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner 1.0 valS 1.0 - 1.0 6.1.1.9 1.0 ko:K01873 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03665 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 GH5_11 1.0 MGYG000000301_00138 1.0 valine--tRNA ligase. valyl-tRNA synthetase. - ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01873:VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 820232 632000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478936 865025 0 0 0 0 0 426547 +AAGETVDVIGTSK MGYG000000223_03139 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,36DP8@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit 1.0 rplC 1.0 - 1.0 - 1.0 ko:K02906 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_03139 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02906:RP-L3, MRPL3, rplC; large subunit ribosomal protein L3 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1258198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1370356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGEVLTQAK MGYG000002298_00115 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp000436615|m__MGYG000002298 1.0 COG1879@1|root,COG1879@2|Bacteria,1V11T@1239|Firmicutes,248RJ@186801|Clostridia,27TBD@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_00115 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGF(Oxidation[F](Phe->Tyr)DVELTYSDNETDR MGYG000000171_01145 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3Y2A7@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10546 1.0 ko02010,map02010 1.0 M00216 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.5 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_01145 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10546:chvE; putative multiple sugar transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 768674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGFAEPSWIDK MGYG000002438_01893 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,2FQ86@200643|Bacteroidia,22X9Z@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase family, NAD-binding Rossmann fold 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01893 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 905227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1820887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGFAEPSWIDKMK MGYG000002438_01893 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF4Q@976|Bacteroidetes,2FQ86@200643|Bacteroidia,22X9Z@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase family, NAD-binding Rossmann fold 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA,GFO_IDH_MocA_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01893 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131260 0 0 0 0 0 0 0 0 973783 0 0 0 0 0 0 0 0 460966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179729 0 0 0 0 0 0 0 0 177664 0 0 0 0 0 0 0 0 289327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 367131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 680546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1044215 0 0 0 0 0 0 0 0 2652194 0 0 0 0 0 0 0 0 1550812 0 0 0 0 0 0 0 0 +AAGFDPYEIVK MGYG000003589_01350 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Dysosmobacter|s__Dysosmobacter sp900770295|m__MGYG000003589 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,2N6EY@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 GGGtGRT protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003589_01350 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1389384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2462269 0 0 0 0 0 0 0 0 3060675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 37696405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGFEIPED(Cation_Ca[II])ATILAAEC(Carbamidomethyl)K MGYG000003452_00078;MGYG000001490_00318;MGYG000000756_00970;MGYG000003683_01140 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003452_00078 0.25 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]|K15515:sauS; sulfoacetaldehyde dehydrogenase [EC:1.2.1.81] 1.0 none 1.0 0 0 40173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 40129 0 0 0 0 69800 0 0 348980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271185 0 0 0 0 588106 0 0 136355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGFEIPED(Cation_Na)ATILAAEC(Carbamidomethyl)K MGYG000003452_00078;MGYG000001490_00318;MGYG000000756_00970;MGYG000003683_01140 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003452_00078 0.25 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]|K15515:sauS; sulfoacetaldehyde dehydrogenase [EC:1.2.1.81] 1.0 none 1.0 0 0 192171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163668 0 0 456122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 486478 0 0 0 0 676857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 415521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGFEIPEDATILAAEC(Carbamidomethyl)K MGYG000003452_00078;MGYG000001490_00318;MGYG000000756_00970;MGYG000003683_01140 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003452_00078 0.25 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]|K15515:sauS; sulfoacetaldehyde dehydrogenase [EC:1.2.1.81] 1.0 none 1.0 295265 433395 2787967 244404 574747 378892 0 0 0 0 287122 0 521411 343339 0 469663 0 349478 0 398960 0 376806 286137 294051 0 0 0 302418 420872 368086 708672 324504 1571076 0 0 0 0 1925969 557741 1222732 6825968 711193 1908437 3069309 723097 0 0 0 900018 0 1538475 544433 0 836622 0 1115953 0 707461 0 2027690 434795 5238276 0 671307 0 890163 1119587 691593 8653763 1297507 6477453 0 0 606726 588131 9203675 623862 812647 2032223 70843 2575499 1702961 2950575 0 0 0 1729938 0 406835 2446131 0 518307 0 0 0 499756 0 624163 782338 1478035 0 598370 0 990000 1638301 1588665 460601 0 4422282 0 0 2384366 570157 1829566 298246 306820 727919 404507 462482 948189 341293 0 0 0 337942 0 332594 219158 0 192389 0 0 0 354331 0 1550749 422980 208813 0 238055 0 0 316541 247016 123856 642898 196694 0 0 93896 327321 306441 327345 197502 37042 5619518 0 145448 0 0 0 0 238665 0 7146478 539724 0 3263425 0 0 0 0 0 1689715 0 60525 0 251004 0 189377 254818 0 51884 0 1294077 0 0 362380 0 293740 +AAGFENLK MGYG000000198_02425;MGYG000002835_00157;MGYG000000179_00718 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,21Y18@1506553|Lachnoclostridium 0.6666666666666666 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_02425 0.3333333333333333 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Vitamin B6 metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00831:serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 6658457 0 0 0 0 0 7565299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6141771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2787094 0 0 0 0 0 0 3378994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3116224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6328579 0 5159666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGFISAEEMANFK MGYG000000198_00669 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,267SM@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_00669 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 869124 566127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1179775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 755086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1185476 1067333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1212055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754699 940167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 453992 0 0 0 0 0 0 0 0 +AAGFLTR MGYG000000201_02593;MGYG000000142_00583;MGYG000002925_00054;MGYG000000301_01483;MGYG000000171_01362;MGYG000000200_02986;MGYG000003012_00713;MGYG000000050_00963;MGYG000000133_01062;MGYG000000212_00914;MGYG000002966_01975;MGYG000001338_00476;MGYG000000002_00954;MGYG000000216_00022;MGYG000000213_02255;MGYG000000806_00037;MGYG000001319_01287;MGYG000003694_00799;MGYG000000489_02402 domain d__Bacteria 1.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae 0.7894736842105263 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 0.8421052631578947 rpsI 1.0 - 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_02593 0.05263157894736842 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02996:RP-S9, MRPS9, rpsI; small subunit ribosomal protein S9 1.0 none 1.0 313078 3376712 2172855 0 2701014 3107311 1208298 1762674 1272738 1629645 2708519 2329162 2590056 1334202 1220742 2405417 1802737 1913000 1181862 1576526 2028483 3485350 2161387 1876109 0 1353219 1364986 2265968 2502889 2059372 2367713 2983064 1854832 1607142 1597824 1165239 329469 2301576 3041535 9089867 1962619 2200101 3103545 1833981 2938240 2610372 0 2336250 3258574 1575045 2778308 2097354 1671047 1531980 1825414 2825115 1651454 2462206 2320664 1161702 1647536 2223305 2041771 2274085 2744143 2423308 4339206 2650888 10579534 3455505 2197445 3091814 3318313 3113817 2375451 2502841 2241949 5943796 2754881 2249310 1057334 2283356 2044622 2535444 1347960 2296458 2112624 2158511 2705758 2154657 2154006 3012735 4034829 905199 2078919 2353320 2458978 4210496 1815057 2456592 2136159 2061392 2530803 2323954 2881359 2793461 3974210 6022119 3625951 2804635 2351867 1572802 2162216 2472683 903657 1142107 1087687 761140 1013683 717769 657430 684443 857915 834045 1174034 1230434 1289890 662233 605948 768330 714532 444826 607224 819596 834905 608632 292832 864150 613485 786254 684432 583094 1112233 864368 1178016 1479099 1100911 805442 734693 838683 685477 843737 11406548 19102459 13509463 11560882 5208536 8251808 14717702 11433492 8168132 12166568 15046547 10235263 7372060 16059536 11392890 10436473 8956680 2375657 9646386 5005903 12010012 12812491 3588024 8351919 9637545 12361650 11916032 4021563 14935373 0 13198254 16257687 18954883 10266820 9250206 10925884 6375900 9049318 +AAGFLTRDPR MGYG000000201_02593;MGYG000000200_02986;MGYG000001338_00476 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 1.0 rpsI 1.0 - 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_02593 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02996:RP-S9, MRPS9, rpsI; small subunit ribosomal protein S9 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGFVDKEGK MGYG000002528_00223 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,267YK@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K01989 1.0 - 1.0 M00247 1.0 - 1.0 - 1.0 ko00000,ko00002,ko02000 1.0 - 1.0 - 1.0 - 1.0 ABC_sub_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00223 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01989:K01989; putative tryptophan/tyrosine transport system substrate-binding protein 1.0 none 1.0 0 168280 0 0 0 146092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208881 0 0 0 0 0 0 606525 0 330468 0 0 0 0 0 0 0 0 1245092 0 0 0 752758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 595471 0 1071057 0 0 0 0 915151 0 726089 940973 0 0 0 0 0 0 0 1495653 0 0 0 942609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2709438 0 788422 0 0 0 0 1999984 0 531682 2392487 0 0 0 0 0 0 0 1070279 0 0 0 216872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382017 0 419036 0 0 0 0 683244 0 1305890 1249912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3564 0 0 0 0 0 0 +AAGFVNLK MGYG000002517_01229;MGYG000000489_01917;MGYG000000271_00398;MGYG000000146_00520;MGYG000000133_00443 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia 0.6 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01229 0.2 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Vitamin B6 metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00831:serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52] 1.0 none 1.0 0 0 237209 0 0 0 314907 0 0 0 0 0 0 800097 498536 0 472835 0 0 0 636592 0 0 0 0 0 0 0 0 0 0 124436 417296 436813 0 734592 0 344667 0 0 0 0 0 0 332702 0 0 0 0 0 0 595918 70379 0 0 0 0 0 75685 0 0 0 0 0 0 0 0 0 0 133010 0 0 0 0 0 0 0 0 141285 0 0 0 0 0 0 0 0 0 0 103723 0 0 358093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192542 0 0 0 0 170312 0 0 0 0 0 0 226365 0 0 0 0 0 0 0 0 0 0 0 0 0 588002 0 0 0 0 0 0 0 0 0 0 0 0 144881 0 0 0 677825 0 0 1562401 0 0 0 3525700 0 1113610 0 0 0 0 3398745 2363841 0 1713085 0 0 0 3379280 0 0 0 0 0 0 0 0 0 0 2301804 2549290 2653494 0 1861327 0 859870 +AAGFVTR MGYG000000223_03182 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,36IRJ@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the universal ribosomal protein uS9 family 1.0 rpsI 1.0 - 1.0 - 1.0 ko:K02996 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_03182 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02996:RP-S9, MRPS9, rpsI; small subunit ribosomal protein S9 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2481171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1135869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGGEAIFC(Carbamidomethyl)K MGYG000001338_01728 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,24DU0@186801|Clostridia,3WS77@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 IQ 1.0 Enoyl-(Acyl carrier protein) reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01728 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 294278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2204659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1475258 0 0 0 0 0 0 0 0 1066797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 425015 0 0 0 0 0 0 0 0 554475 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 593024 0 0 0 0 0 0 0 +AAGGEAQLM(Oxidation)AK MGYG000004540_01479 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__TANB77|f__CAG-508|g__UMGS1754|s__UMGS1754 sp900554815|m__MGYG000004540 1.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,267V8@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity 1.0 rplB 1.0 - 1.0 - 1.0 ko:K02886 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L2,Ribosomal_L2_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004540_01479 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02886:RP-L2, MRPL2, RML2, rplB; large subunit ribosomal protein L2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGGISSLDDAAK MGYG000002485_00103 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0274@1|root,COG0274@2|Bacteria,378X5@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 H 1.0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate 1.0 deoC 1.0 - 1.0 4.1.2.4 1.0 ko:K01619 1.0 ko00030,map00030 1.0 - 1.0 R01066 1.0 RC00436,RC00437 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DeoC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_00103 1.0 deoxyribose-phosphate aldolase. phosphodeoxyriboaldolase. - 2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway 1.0 K01619:deoC, DERA; deoxyribose-phosphate aldolase [EC:4.1.2.4] 1.0 none 1.0 0 0 0 0 0 364642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438721 0 0 0 0 1078929 0 0 1740418 2519386 0 0 0 3178483 3673015 3210032 0 1740420 0 0 4587373 0 2054846 0 0 3005110 0 2241045 1628592 0 1979283 0 2185056 3114290 0 0 0 0 1640110 0 0 0 0 360021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1056828 0 0 1100298 0 0 0 0 1298273 578214 0 0 601515 0 0 829813 0 931414 0 0 0 0 0 962571 0 0 0 945246 0 0 0 0 0 706167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGGISTVD(Methyl[D](Asp->Glu)DMEK MGYG000000195_02256 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_E|m__MGYG000000195 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,3WIFE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate 1.0 deoC 1.0 - 1.0 4.1.2.4 1.0 ko:K01619 1.0 ko00030,map00030 1.0 - 1.0 R01066 1.0 RC00436,RC00437 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DeoC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000195_02256 1.0 deoxyribose-phosphate aldolase. phosphodeoxyriboaldolase. - 2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway 1.0 K01619:deoC, DERA; deoxyribose-phosphate aldolase [EC:4.1.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2057465 0 0 0 0 1388250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGGISTVEDMEK MGYG000000022_01714 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,3WIFE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate 1.0 deoC 1.0 - 1.0 4.1.2.4 1.0 ko:K01619 1.0 ko00030,map00030 1.0 - 1.0 R01066 1.0 RC00436,RC00437 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DeoC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01714 1.0 deoxyribose-phosphate aldolase. phosphodeoxyriboaldolase. - 2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway 1.0 K01619:deoC, DERA; deoxyribose-phosphate aldolase [EC:4.1.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 620501 0 0 0 0 1307935 0 0 0 0 1118200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 497302 0 0 0 0 935333 0 0 0 0 681871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2057375 0 0 0 0 0 0 0 0 0 1468572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 582056 0 0 0 0 496685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3253576 0 0 0 0 2444784 0 0 0 0 2982535 0 0 0 0 0 0 0 0 0 0 +AAGGLAIIGTER MGYG000004876_03018;MGYG000003446_01379;MGYG000002082_00188;MGYG000000196_00565;MGYG000003681_00908;MGYG000003415_00077;MGYG000002281_02559;MGYG000002560_02882;MGYG000001789_02114;MGYG000003279_02202;MGYG000002867_01114;MGYG000000224_00045;MGYG000004720_00894;MGYG000000174_01535;MGYG000001643_03002;MGYG000000074_01471;MGYG000002293_00348;MGYG000000138_02590;MGYG000004468_01109;MGYG000001345_01168;MGYG000004185_00678;MGYG000001661_01341;MGYG000001378_02410;MGYG000000029_02205;MGYG000003952_00490;MGYG000000170_01936;MGYG000001313_02498;MGYG000000105_01224;MGYG000000098_00020;MGYG000004797_04099;MGYG000001346_01064;MGYG000003363_01411;MGYG000003697_01634;MGYG000001783_01010;MGYG000003282_00871;MGYG000000003_01952;MGYG000001415_00080;MGYG000004763_02200;MGYG000000243_00140;MGYG000002561_02517;MGYG000004479_01148 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,2FMVF@200643|Bacteroidia,4AMYA@815|Bacteroidaceae 0.5609756097560976 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane 1.0 secA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 0.9512195121951219 - 1.0 ko:K03070 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 1.0 - 1.0 - 1.0 Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW 1.0 - 1.0 - 1.0 GT41 0.8048780487804879 - 1.0 MGYG000004876_03018 0.024390243902439025 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03070:secA; preprotein translocase subunit SecA [EC:7.4.2.8] 1.0 none 1.0 6612525 3214927 4681316 5842006 4265720 4207735 8550578 0 0 3273945 3819355 0 7380208 4768897 0 7885675 5419886 1790349 3081560 4200253 0 3912180 0 6399744 0 5392892 3641622 1598876 4132204 5282673 5328229 4000436 4230040 4733672 3737224 6945492 3881840 4831955 0 1233499 0 314798 6200200 0 0 0 0 4435103 0 1202537 10382189 0 0 0 0 1565417 4932915 0 0 402542 2253892 1388926 0 5106836 4390906 1166515 4136273 0 0 4632397 4403998 2066730 0 0 4509367 2121834 1399085 5019667 0 1647388 0 805074 5501174 0 0 3262864 564231 523873 0 0 0 0 3996116 677525 1588027 4106546 0 0 3036820 1907882 0 1330466 1171799 2111177 0 883295 1322525 1186211 0 1450811 5016163 4906001 455158 0 2786533 3009701 3631645 2519990 2943504 3553389 3126579 0 0 2857569 2821708 2728477 3081617 2221443 0 3075773 2403205 2915843 3121075 467824 0 3759936 3364932 2387871 0 2976032 2935439 1112772 3224122 2534436 2463411 2853596 3566230 2879628 3098510 3578967 3138904 3239096 2897051 2524180 2762860 2900010 0 0 3005861 0 0 2388204 2745561 3768956 0 2046196 0 0 4153883 1052140 3078508 0 0 2695610 0 0 0 2840061 2309217 0 3233108 5474043 2266294 2549873 1208570 3123273 2596323 2402817 0 3251265 +AAGGLAIIGTERHESR MGYG000004876_03018;MGYG000000196_00565;MGYG000001337_01556;MGYG000003279_02202;MGYG000000224_00045;MGYG000004797_04099;MGYG000001783_01010;MGYG000003363_01411;MGYG000000074_01471;MGYG000001415_00080;MGYG000001345_01168;MGYG000004468_01109;MGYG000004763_02200;MGYG000000243_00140 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,2FMVF@200643|Bacteroidia,4AMYA@815|Bacteroidaceae 0.7142857142857143 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane 1.0 secA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 1.0 - 1.0 ko:K03070 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 1.0 - 1.0 - 1.0 Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW 1.0 - 1.0 - 1.0 GT41 0.8571428571428571 - 1.0 MGYG000004876_03018 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03070:secA; preprotein translocase subunit SecA [EC:7.4.2.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGGLNAAETKPQAK MGYG000003022_00004;MGYG000003352_01218 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG1053@1|root,COG1053@2|Bacteria,1R0GI@1224|Proteobacteria 1.0 1224|Proteobacteria 1.0 C 1.0 FAD binding domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003022_00004 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2640512 2554240 3454841 2988413 3235161 2678306 2217364 4763107 2954389 3516957 3397121 2598488 2476009 2850999 2714169 2755095 2316737 881113 2749895 2147792 2350124 2401028 1340844 1962631 2598392 2896868 2697678 1002355 2693225 2367756 2388217 2627040 3388762 2572979 5210800 2437750 2470464 3096522 942612 1403972 1086379 958478 1544762 1869603 1263203 2405916 924889 1027871 1274101 1383755 920721 1026227 848248 1061992 1014521 1689894 1119460 901313 1015250 1099885 1395194 1718109 863041 281757 1229774 1356380 1192387 1230890 1644465 1442705 795405 1113040 2730396 1647004 857548 991977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249002 0 0 0 0 0 0 191660 227930 0 0 171031 0 0 0 0 186169 0 101775 214642 64534 0 0 0 0 0 0 0 0 226256 143080 145169 0 0 201583 0 169601 0 +AAGGLNAAGTALQQAK MGYG000001410_01025 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__Sutterella wadsworthensis_A|m__MGYG000001410 1.0 COG1053@1|root,COG1053@2|Bacteria,1R0GI@1224|Proteobacteria,2WF5S@28216|Betaproteobacteria,4PQ7T@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 C 1.0 FAD binding domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001410_01025 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1721383 0 0 0 0 1358288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1302055 0 0 0 +AAGGMDDGGFGTSFEK MGYG000000179_02179;MGYG000000262_00845 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes,24N8B@186801|Clostridia,22050@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 S 0.5 PTS system fructose IIA component 1.0 - 1.0 - 1.0 2.7.1.121 1.0 ko:K05881 1.0 ko00561,map00561 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000,ko02000 1.0 - 1.0 - 1.0 - 1.0 EIIA-man 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_02179 0.5 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism 1.0 K05881:dhaM; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaM [EC:2.7.1.121] 1.0 none 1.0 0 0 0 0 0 388524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 671691 0 315680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 473076 0 370962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 977876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1208868 0 374647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1747877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1567398 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525913 0 496886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGGNIIPSSTGAAK MGYG000000074_00883;MGYG000004658_00366 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,22V16@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00883 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 582602 0 0 386773 191964 0 590611 0 352258 0 0 0 149976 275624 0 190891 537101 0 0 388550 0 0 0 575023 572797 506675 511356 0 408288 304353 0 0 0 0 0 717497 445097 0 2200469 1745171 2289049 2421462 2033359 1476970 1550145 2507322 2576164 2631746 1686486 1867924 1332223 2491671 2688761 2004984 1684929 0 2814827 3479970 2407463 1560350 0 1358760 1952704 2519134 2343739 0 1689407 2478684 1567457 2238341 2105455 2742877 2857900 2210264 2300260 2361737 0 0 0 0 0 0 135258 0 0 0 0 52875 0 0 0 0 0 0 0 0 0 0 0 100451 0 0 0 0 0 0 0 0 0 0 0 0 96619 0 401830 0 0 138634 0 178905 158104 549234 509926 0 0 634998 0 0 874083 0 0 0 470637 493032 749552 0 0 0 554436 858292 479139 0 0 303372 0 351617 0 0 740885 697127 597070 0 15765635 10639435 12700265 20978306 19601064 19434074 12590327 15446981 18739455 14368371 7610433 15616391 19724208 9156489 14373517 14344792 16945594 1360004 26503279 32470743 12356126 13521038 1298668 14514298 12447508 23821032 11769577 1197839 15481093 24558134 13017594 12209745 10459761 1019618 12985384 12992033 17355409 14549834 +AAGGSNYMYDINDAELNK MGYG000002882_00261 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435975|m__MGYG000002882 1.0 COG0747@1|root,COG0747@2|Bacteria,1TSBC@1239|Firmicutes,24B65@186801|Clostridia,2PQYQ@265975|Oribacterium 1.0 186801|Clostridia 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002882_00261 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306480 0 0 0 0 760082 0 0 0 0 692068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGGTVFTAEEAK MGYG000000154_01299;MGYG000002517_00535;MGYG000002492_00656;MGYG000000245_02013;MGYG000000389_02154 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Carbamoyl-phosphate synthetase ammonia chain 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000154_01299 0.2 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01955:carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] 1.0 none 1.0 595572 0 363797 329655 0 0 0 364198 394121 0 0 0 344158 597604 545943 0 0 0 321456 395459 0 0 0 0 682913 613282 692761 0 0 764800 0 0 366050 0 695825 345337 701739 464957 0 0 0 423036 0 0 0 0 0 0 0 0 0 304246 0 0 0 0 0 0 0 0 0 0 0 312387 0 0 0 0 0 0 0 0 0 0 0 0 618556 0 883203 422327 0 0 0 679217 726802 0 0 0 674700 609568 668080 0 0 0 385613 686315 0 0 0 0 1011068 653692 683237 0 0 751824 0 0 919905 0 597313 560882 821650 904096 1089459 0 0 1259154 0 0 0 981250 1288515 0 0 0 0 1282228 1080578 0 0 0 730618 1347985 0 0 0 0 1401186 1093395 1272711 0 0 789648 0 0 357452 0 1260436 1049619 860959 219985 417723 0 500934 230821 0 0 0 920522 640721 0 0 0 366839 795727 625954 0 0 0 450605 0 0 0 0 0 655439 250560 552412 0 0 375163 0 0 331984 0 529487 509010 493319 455278 +AAGGTVFTAEEAKEVANR MGYG000002517_00535;MGYG000000389_02154 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Carbamoyl-phosphate synthetase ammonia chain 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00535 0.5 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01955:carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] 1.0 none 1.0 388036 0 0 455398 0 0 0 0 346009 0 0 0 0 481977 447839 0 0 0 455331 381579 0 0 0 0 0 496309 96496 0 0 505186 0 0 0 0 382817 176737 390047 0 404110 0 0 271985 0 0 0 0 160120 0 0 0 0 125238 198846 0 0 0 0 369966 0 0 0 0 0 255998 159281 0 0 255251 0 0 0 0 269668 489826 158023 0 164731 0 0 232626 0 0 0 0 254152 0 0 0 0 165195 313376 0 0 0 0 201702 0 0 0 0 0 294843 192669 0 0 219255 0 0 0 0 373375 213580 441345 0 1106120 0 0 771167 0 0 0 0 1292496 0 0 0 0 1274484 1231690 0 0 0 811725 902249 0 0 0 0 0 1073490 1030702 0 0 702821 0 0 0 0 1254748 978571 1259203 0 264447 0 0 0 0 0 0 0 412477 0 0 0 0 229697 347624 0 0 0 314722 89004 0 0 0 0 0 288750 165333 0 0 360048 0 0 0 0 171639 273931 464113 0 +AAGGVIIITTK MGYG000002438_00861;MGYG000001489_04986 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,22WS3@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00861 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2764215 0 0 0 0 0 0 0 0 0 2613943 0 0 0 0 0 0 0 0 0 0 0 2544672 0 +AAGGVILITTK MGYG000002438_00861;MGYG000002218_02008;MGYG000000355_00074;MGYG000002478_00138;MGYG000002834_00163;MGYG000001489_04986;MGYG000003521_00292;MGYG000001666_00694;MGYG000003697_02612;MGYG000002080_00857 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia 0.4 976|Bacteroidetes 1.0 P 0.9 TonB-linked outer membrane protein, SusC RagA family 0.6 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00861 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 195466 0 0 0 123444 0 165353 113947 199483 0 129555 0 136650 0 161752 200724 203109 0 277079 0 0 0 226152 256409 0 200562 0 0 0 263277 141067 0 125951 560011 157502 577698 488215 258097 503093 0 343560 0 445431 214554 1257736 380119 534659 539348 0 437139 0 415091 387084 0 514872 301542 466784 482087 593860 561892 148910 129896 705135 278574 441135 475128 0 0 511839 328249 565649 444092 322148 379084 260361 397735 207628 0 318245 0 326624 0 942381 458409 0 254253 320578 269741 0 171374 241244 1059191 0 0 368076 174692 286048 0 0 0 546595 369867 308008 463874 0 367121 241037 281990 382800 1087688 1013518 1771324 797937 1492867 1615617 0 956420 0 775154 718814 1204737 1319971 844574 957665 1100199 669514 496057 695603 517309 1617967 1238176 1233772 1051094 906894 1124510 877312 307809 728470 693247 849879 1762788 1171456 0 1013276 830375 884491 1521676 0 4353983 1936319 2221229 0 2347423 0 2943415 0 3322891 2758956 7071467 3705565 2585291 0 3729479 2874775 1518787 2628987 2923901 9341747 2796535 1135361 3473036 0 0 0 1158699 3130501 9371146 2371831 8629655 1429054 0 2520261 2018915 0 2138305 +AAGGVILITTKR MGYG000002438_00861;MGYG000002218_02008;MGYG000000355_00074;MGYG000002478_00138 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,22WS3@171551|Porphyromonadaceae 0.75 976|Bacteroidetes 1.0 P 0.75 TonB dependent receptor 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00861 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 61608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127717 0 0 0 0 0 0 0 0 78918 0 62572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740013 351418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1038801 323153 0 233745 0 0 0 0 0 1118394 0 832279 0 0 0 0 0 0 +AAGGVILVTTK MGYG000003351_03677;MGYG000002171_02797 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FWW6@200643|Bacteroidia,4AWE3@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 H 0.5 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003351_03677 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 270847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 954278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGGVVLITTK MGYG000002438_00862;MGYG000002438_04047 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,22WS3@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 0.5 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00862 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380445 0 0 0 0 0 0 0 0 280735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4877367 0 0 0 0 0 0 0 0 1427140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGI(Xle->Val)QILNTSGAPGEGAK MGYG000004763_01415 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FN3Y@200643|Bacteroidia,4AP89@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004763_01415 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1586705 0 0 0 0 0 2250667 0 0 0 1320779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2030022 0 0 0 0 0 0 0 1728983 0 0 0 0 7578510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIADDKTEVTNK MGYG000004769_01211 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG1633@1|root,COG1633@2|Bacteria,1V6KG@1239|Firmicutes,4H9J5@909932|Negativicutes 1.0 909932|Negativicutes 1.0 S 1.0 PFAM Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 COQ7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01211 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 212053 0 0 256496 218069 0 0 76819 0 108867 169715 0 0 0 0 0 0 0 152133 0 0 0 0 0 0 0 0 0 0 0 0 0 74229 0 0 0 0 0 1583703 2426058 2388598 1335497 3187291 2212064 1200641 1990058 0 1892663 3026708 0 0 1870031 0 0 1665106 0 1422598 0 1444984 2291291 0 1868562 1395888 1404681 1633999 0 1443324 1732645 1946165 2999530 2406810 0 2023321 1439984 1311514 2059030 1219929 1555006 1855778 1098846 2969151 2420831 1967889 2016476 0 1445605 1971898 0 0 1698408 0 0 1032864 0 1416715 0 1358622 1409162 0 2225277 1738592 1548587 1471662 0 1461809 1597029 2250712 1561902 1086470 0 1047209 1677114 1292293 1473631 830030 187177 894662 354082 657405 780188 875510 924670 0 889881 599402 0 0 742382 0 0 547581 0 509659 0 706531 816540 0 464350 582109 581147 708260 0 580955 666951 363142 688150 943995 0 1009739 794240 824489 274816 0 0 0 0 0 0 0 0 0 0 209364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147766 0 0 0 0 0 +AAGIAEAR MGYG000001292_02345 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,4CZCD@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001292_02345 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 213380 0 0 0 0 768396 0 0 940419 0 950747 0 471989 0 0 386654 0 0 0 0 240930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1119986 0 0 0 0 2771552 0 0 1431887 0 3337100 0 2801777 0 0 1765446 0 0 0 0 3277485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 205164 0 0 0 0 221206 0 0 902341 0 368153 0 871273 0 0 744699 0 0 0 0 843250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310962 0 0 457649 0 720260 0 482037 0 0 114270 0 0 0 0 351455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341721 0 0 0 0 1260659 0 0 198727 0 375435 0 181406 0 0 230052 0 0 0 0 96725 0 0 0 0 0 0 0 0 0 0 +AAGIAENVK MGYG000002494_02447 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0099@1|root,COG0099@2|Bacteria,1RD1G@1224|Proteobacteria,1S3NX@1236|Gammaproteobacteria,3XPPN@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits 1.0 rpsM 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02952 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S13 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02447 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02952:RP-S13, rpsM; small subunit ribosomal protein S13 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1099897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIAEVFTPGTPTGNIVEFINANVK MGYG000004769_01825 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,4H4FB@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 B12- binding domain protein 1.0 - 1.0 - 1.0 5.4.99.2 1.0 ko:K01849 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00375,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01825 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01849:E5.4.99.2B, mcmA2; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] 1.0 none 1.0 0 0 577902 0 200453 0 0 0 0 0 0 0 0 0 646639 0 0 0 0 0 0 0 0 0 0 623455 0 0 327145 1547181 0 0 0 0 0 0 0 255444 20651398 4770060 8271390 0 26542005 1819729 0 0 0 0 7889863 1487466 0 0 35080624 0 0 0 0 0 0 15734367 0 28976183 0 3155501 21883688 0 25824200 10868054 0 51581974 34111897 8253916 46783861 12260519 28317052 36966309 379628 2691702 2533801 0 27607303 14323755 0 0 0 0 7023662 812865 0 0 12838916 0 0 0 0 0 0 8281761 0 7321289 0 16985226 1458298 0 6568402 321939 0 7256114 2236262 1843607 19220288 4108783 16410063 9684570 0 0 4174248 0 0 0 0 0 0 0 0 2340756 0 0 3473938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4456591 0 0 0 0 0 0 0 12696133 17623005 0 16557288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 39595936 0 0 0 0 0 +AAGIAEVFTPGTPTSK MGYG000000591_01065;MGYG000001365_01211 genus d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A 1.0 COG2185@1|root,COG2185@2|Bacteria,1V3QN@1239|Firmicutes,4H4FB@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 B12- binding domain protein 1.0 - 1.0 - 1.0 5.4.99.2 1.0 ko:K01849 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00375,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 B12-binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000591_01065 0.5 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01849:E5.4.99.2B, mcmA2; methylmalonyl-CoA mutase, C-terminal domain [EC:5.4.99.2] 1.0 none 1.0 1066128 0 0 920417 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257989 0 0 0 0 0 0 0 0 0 245950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283010 0 0 0 0 0 0 0 5163361 0 5997286 11092041 4934043 7433238 6674337 8692616 6902792 4944877 4326738 5040040 3733335 0 4776411 2777444 6367195 9217631 5701921 6415506 0 6582064 7665215 7050307 0 5526631 0 6477690 7188511 5559799 6672304 6590255 5944750 6427322 8850076 0 9325807 7339735 +AAGIALTDTFVK MGYG000004536_01441;MGYG000002867_00573;MGYG000001562_00044;MGYG000004006_01717;MGYG000000053_01377;MGYG000004756_01346;MGYG000002007_00386;MGYG000001415_02219;MGYG000001546_00360;MGYG000000003_00712 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,22V16@171550|Rikenellaceae 0.9 976|Bacteroidetes 0.9 G 0.9 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.9 gap 0.9 - 1.0 1.2.1.12 0.9 ko:K00134 0.9 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9 R01061 0.9 RC00149 0.9 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004536_01441 0.1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9 0.9 0.9 0.9 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9 none 1.0 9137639 6273728 3166831 9143720 2806299 5845774 10698492 4404817 9098516 6124232 2529795 7602601 3460873 7005245 6987548 5007318 6412706 0 9532434 9261265 8455369 4819183 0 7711376 6565616 8830242 11092433 0 8157343 9331651 4096474 5664866 3826416 3440179 6665094 10960322 7621237 2286142 1542630 1171274 2540584 1967525 2579597 2112016 1114307 1343160 2404284 2492949 1734039 0 1910050 2524227 2857754 2805104 0 0 1823715 1862768 3301863 2068369 0 0 2129561 1966303 2123820 0 1596594 2509398 1607554 2112962 2061621 271042 1421225 1632619 1948938 2412323 3560818 2535539 4336440 1988556 4693285 2097694 3616418 0 3929835 2469894 3192237 4427332 2415345 3131096 3315573 2738196 1758618 0 2901517 3198977 4504768 2199714 0 2718008 2916604 3033965 2414268 0 3295000 5481647 2891582 2023953 3826719 3845531 2631276 4292345 2665441 4681610 1575025 1352805 2080017 1089457 1928420 1589750 1653646 1975846 1496800 1587691 1412978 0 1665557 1772116 1996861 1669509 1435840 0 1959490 1378988 2227372 1000852 0 1008045 1827993 1895468 1571908 0 1836021 1802783 1878308 2246163 2026196 1909330 1661080 1707887 2200682 1496992 347151 316230 0 0 170776 206745 309796 0 237250 0 0 325271 114454 0 0 202163 125159 0 315849 781111 353455 257731 0 184222 375165 302362 125345 0 0 682399 0 165110 108611 0 0 311993 170584 133455 +AAGIAVQAFGYHNR MGYG000002517_01108 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 PFAM Aminotransferase class-III 1.0 argD 1.0 - 1.0 2.6.1.11,2.6.1.17 1.0 ko:K00821 1.0 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00028,M00845 1.0 R02283,R04475 1.0 RC00006,RC00062 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01108 1.0 acetylornithine transaminase. | succinyldiaminopimelate transaminase. succinylornithine aminotransferase. | succinyldiaminopimelate transferase. Also acts on L-ornithine and N(2)-succinyl-L-ornithine. 2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L- glutamate 5-semialdehyde. | 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (S)-2- succinylamino-6-oxoheptanedioate + L-glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00821:argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433254 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3334416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3363945 0 0 3923851 0 0 0 0 0 3692940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIDAQVIDPAEAR MGYG000003681_02758;MGYG000001661_00109 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0578@1|root,COG0578@2|Bacteria,4NJ15@976|Bacteroidetes,2FR3V@200643|Bacteroidia,4AQ69@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,DAO_C,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_02758 0.5 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1608055 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIDQEFVQDNQSSSR MGYG000000133_00721;MGYG000000301_00793 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1208@1|root,KOG1322@2759|Eukaryota,39UI6@33154|Opisthokonta,3BMQM@33208|Metazoa,3DRBA@33213|Bilateria,42230@6656|Arthropoda,3SQNT@50557|Insecta 1.0 33208|Metazoa 1.0 M 1.0 MobA-like NTP transferase domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 NTP_transferase,RmlD_sub_bind,dTDP_sugar_isom 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00721 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 576173 0 0 0 0 0 0 937391 663839 0 0 841531 517277 0 0 0 0 0 0 0 0 0 657514 0 861350 0 0 0 0 0 1009242 0 0 690206 0 554120 +AAGIDSVLSTGK MGYG000002494_02986 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0770@1|root,COG0770@2|Bacteria,1QTSF@1224|Proteobacteria,1RMGD@1236|Gammaproteobacteria,3XMEK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 M 1.0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein 1.0 murF 1.0 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.0 6.3.2.10 1.0 ko:K01929 1.0 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 1.0 - 1.0 R04573,R04617 1.0 RC00064,RC00141 1.0 ko00000,ko00001,ko01000,ko01011 1.0 - 1.0 - 1.0 iB21_1397.B21_00086,iEC042_1314.EC042_0087,iEC55989_1330.EC55989_0082,iECBD_1354.ECBD_3531,iECB_1328.ECB_00087,iECD_1391.ECD_00087,iECIAI1_1343.ECIAI1_0085,iECO103_1326.ECO103_0088,iECO111_1330.ECO111_0089,iECO26_1355.ECO26_0089,iECSE_1348.ECSE_0088,iECW_1372.ECW_m0085,iEKO11_1354.EKO11_3828,iEcE24377_1341.EcE24377A_0088,iEcHS_1320.EcHS_A0092,iEcolC_1368.EcolC_3571,iSBO_1134.SBO_0074,iSSON_1240.SSON_0094,iSbBS512_1146.SbBS512_E0079,iUMNK88_1353.UMNK88_86,iWFL_1372.ECW_m0085,iYL1228.KPN_00090 1.0 Mur_ligase,Mur_ligase_C,Mur_ligase_M 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02986 1.0 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase. uridine diphosphoacetylmuramoylpentapeptide synthetase. Involved with EC 6.3.2.4, EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.8 and EC 6.3.2.9 in the synthesis of a cell-wall peptide.-!-Also catalyzes the reaction when the C-terminal residue of the tripeptide is meso-2,6-diaminoheptanedioate (acylated at its L-center), linking the D-Ala--D-Ala to the carboxy group of the L-center.-!-Formerly EC 6.3.2.15. ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma- D-glutamyl-L-lysine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D- muramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine. 1.0 1.0 1.0 1.0 Lysine biosynthesis|Peptidoglycan biosynthesis|Metabolic pathways|Vancomycin resistance 1.0 K01929:murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIDTASGVPNK MGYG000003937_00913;MGYG000001157_02091;MGYG000004732_00999;MGYG000001627_00366 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WICR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 - 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_00913 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02867:RP-L11, MRPL11, rplK; large subunit ribosomal protein L11 1.0 none 1.0 0 968582 495186 851497 0 999597 652341 841423 0 0 0 788630 0 947796 0 1100710 1006707 1778051 0 991471 1040639 937165 1664030 520131 0 0 0 1182008 0 700114 785437 0 910980 989393 0 1084191 0 620886 0 504782 705335 315834 0 482727 283818 653075 0 0 0 2165793 0 247161 0 487227 533394 1287393 0 342349 259127 481805 1713410 0 0 0 0 1591923 0 1643057 484428 0 770637 858284 0 379286 0 786132 0 721689 978529 789445 0 973862 824490 801439 0 0 0 938807 0 909920 0 843033 1204796 1419731 0 724062 1019853 866684 1244755 767939 0 0 0 1305327 0 1042142 1026085 0 691442 877801 0 805198 0 898618 0 959618 1052367 581074 0 1417898 1090261 594555 0 0 0 672839 0 813640 0 1323846 538135 1166331 0 1026693 480022 654962 457996 1839133 0 0 0 1232775 0 606488 1320644 0 896530 647135 0 870504 0 1283854 0 501132 559326 515038 0 472146 792726 961813 0 0 0 1734623 0 194608 0 726836 709318 3393474 0 612923 791875 701488 3611523 655753 0 0 0 3461735 0 872159 632437 0 329886 827535 0 1019132 0 628806 +AAGIEAAK MGYG000000756_00891;MGYG000002469_01727;MGYG000003383_00235;MGYG000001292_02316;MGYG000002469_00420;MGYG000003683_01099 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria,4CZDH@85004|Bifidobacteriales 0.8333333333333334 201174|Actinobacteria 1.0 G 0.8333333333333334 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate 0.8333333333333334 rpiA 0.8333333333333334 - 0.8333333333333334 5.3.1.6 0.8333333333333334 ko:K01807 0.8333333333333334 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.8333333333333334 M00004,M00007,M00165,M00167,M00580 0.8333333333333334 R01056 0.8333333333333334 RC00434 0.8333333333333334 ko00000,ko00001,ko00002,ko01000 0.8333333333333334 - 1.0 - 1.0 - 1.0 Rib_5-P_isom_A 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000756_00891 0.16666666666666666 ribose-5-phosphate isomerase. ribose phosphate isomerase. Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate. aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate. 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.8333333333333334 K01807:rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] 0.8333333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5762588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 913506 0 0 0 0 2179910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIEKDTFIISC(Carbamidomethyl)DC(Carbamidomethyl)PR MGYG000001300_00586 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Belongs to the ribose-phosphate pyrophosphokinase family 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00586 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00948:PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 344978 0 0 0 0 0 0 0 0 0 390144 0 616423 0 0 0 0 0 0 0 0 0 0 397914 0 0 0 0 887404 512518 829488 0 0 0 0 0 744595 0 956633 0 0 1138085 0 862602 881697 0 763662 0 602630 0 1001581 0 0 0 510426 0 0 0 896576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 123374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1001107 0 0 1045290 673122 848917 0 0 0 0 0 0 0 0 0 0 0 0 1076271 996002 0 0 0 0 0 1098487 0 0 0 985635 957664 0 0 0 0 0 0 0 0 0 0 484495 1847680 480503 0 0 0 0 0 272643 0 624311 0 0 784335 0 0 1339020 0 1106061 0 605104 0 1620699 0 0 0 0 0 0 0 896814 0 0 0 0 +AAGIENFIHVR MGYG000002717_02115;MGYG000001313_03171;MGYG000001661_02103;MGYG000002478_00339;MGYG000004185_02238;MGYG000000098_00636;MGYG000003693_01259;MGYG000000196_02287;MGYG000004571_01786;MGYG000002549_04226;MGYG000001378_04186;MGYG000003363_01959;MGYG000001346_00856;MGYG000001659_02213;MGYG000002540_00968;MGYG000000054_02931;MGYG000003312_00927;MGYG000004797_04223;MGYG000000243_02183;MGYG000003681_00141;MGYG000004763_00640;MGYG000001370_02455;MGYG000000236_01414 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 0.8260869565217391 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 0.8260869565217391 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002717_02115 0.043478260869565216 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 3130514 3048405 2931487 3367536 2580794 2383892 3827041 2914337 3467692 2726586 2728865 2778545 2215980 2959429 2464227 2680190 3343578 1174835 3051951 2502639 2827152 2436909 1561751 3433482 2553133 3867274 3347778 1483817 3193360 3144736 3465195 3370709 2904370 2971370 3277195 3587273 2751466 2841510 2247355 1157465 2274692 2677921 2778341 2231025 2082788 2512109 2758655 2854682 2436451 2821611 2729701 2438278 2814658 2501149 2425714 1242717 3037383 2345211 2533032 1959189 1516040 1794587 2153408 2376219 2803151 1298710 2038160 1982224 1402874 2729524 1864311 2187506 2796042 2170564 2517846 2170059 1953719 1706132 2315211 2098380 2789892 2414122 2885454 2147728 2251113 2124826 2574678 3097125 2179851 2456052 2005479 2019539 1727025 2056315 2243158 2121035 2046160 1726181 1763393 2338835 2284341 2098498 1935265 1570399 2168945 2191373 2420563 1519541 1793034 1373956 2076765 2732747 1907601 1972057 1105346 692084 1085264 969469 873211 774122 998255 1011991 961940 947045 900453 1136015 1036307 893356 1001785 782927 1027601 627288 1418217 1202274 1191860 782915 737035 631654 1019410 1035445 1036032 272239 922727 1074045 860911 1185203 883137 1144988 1087505 1249628 1163922 777912 1576114 1143086 1178480 1672049 2698996 1851887 1683267 2189704 1770320 1086602 1404829 1198170 1178712 967189 1356072 1726306 1541088 1768978 1715256 2212772 1124837 1646186 1495672 1772550 1413071 1353640 1371567 1368644 1968706 1983988 1453999 1386061 904054 1797707 2775240 1039066 1474007 1487788 +AAGIEPVGRPEVSVDSASEAEGATLTVK MGYG000002545_00080;MGYG000002040_00240 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3WGS8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase 1.0 tig 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K03545 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FKBP_C,Trigger_C,Trigger_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002545_00080 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03545:tig; trigger factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053553 0 0 0 0 940132 0 0 0 0 993858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 691029 0 0 0 0 495322 0 0 0 0 728851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766572 0 0 0 0 783064 0 0 0 0 880226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188038 0 0 0 0 450414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIEQDFK MGYG000000243_01798 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0436@1|root,COG0436@2|Bacteria,4NENS@976|Bacteroidetes,2FMU2@200643|Bacteroidia,4AKGF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 COG0436 Aspartate tyrosine aromatic aminotransferase 1.0 aspC 1.0 - 1.0 2.6.1.1 1.0 ko:K00812 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 - 1.0 R00355,R00694,R00734,R00896,R02433,R02619,R05052 1.0 RC00006 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01798 1.0 aspartate transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00812:aspB; aspartate aminotransferase [EC:2.6.1.1] 1.0 none 1.0 0 0 1673193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2563840 0 0 0 0 2265200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIESC(Carbamidomethyl)AFDR MGYG000003022_00716;MGYG000003170_00066;MGYG000001410_00792 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae 1.0 COG0098@1|root,COG0098@2|Bacteria,1MUS4@1224|Proteobacteria,2VQ80@28216|Betaproteobacteria,4PQ4Q@995019|Sutterellaceae 0.6666666666666666 28216|Betaproteobacteria 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 0.6666666666666666 rpsE 0.6666666666666666 - 1.0 - 1.0 ko:K02988 0.6666666666666666 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003022_00716 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1069367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295661 0 0 844929 0 0 0 0 831472 0 0 214247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407747 0 0 0 0 0 0 0 279984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251310 0 0 0 0 0 0 0 391571 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150990 0 0 184988 0 0 0 0 593641 +AAGIGGKGER MGYG000000255_02207;MGYG000000205_02701;MGYG000000233_02503 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,268N0@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000255_02207 0.3333333333333333 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 12448 19495 0 0 179560 0 98463 47744 257844 0 0 0 0 0 0 0 16386 0 85658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111072 175007 0 0 220782 0 80114 277178 92843 0 0 0 0 0 0 0 0 0 185771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190663 0 31896 80007 62144 0 0 0 0 0 0 0 26368 0 311202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132060 320128 0 0 78683 0 0 208734 80072 0 0 0 0 0 0 0 104189 0 84339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 33912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIGGRGER MGYG000000378_00784 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__|s__|m__MGYG000000378 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,21XUV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000378_00784 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIGNIHGK MGYG000000233_01876;MGYG000000146_01173;MGYG000001319_01217;MGYG000000249_00065;MGYG000000217_00827;MGYG000000187_01350;MGYG000002772_00870;MGYG000000127_03839;MGYG000002141_00573;MGYG000000018_00752;MGYG000000142_01854;MGYG000002517_00490;MGYG000001423_01022;MGYG000001637_01196;MGYG000000262_02902;MGYG000002279_01206;MGYG000000223_01963;MGYG000000205_02362;MGYG000000179_01100;MGYG000000258_00162;MGYG000000198_00983;MGYG000001683_00168;MGYG000003694_02365;MGYG000000045_02322;MGYG000000484_00946;MGYG000000136_02629;MGYG000001315_01431;MGYG000000312_01744;MGYG000002492_00628;MGYG000000171_01775;MGYG000003921_02276;MGYG000000084_01948;MGYG000000216_03192;MGYG000000089_02421;MGYG000001338_00333;MGYG000000271_03469;MGYG000002974_01498;MGYG000001374_02205;MGYG000004296_00424;MGYG000002278_02388;MGYG000000077_01332;MGYG000000200_03096;MGYG000000076_01227;MGYG000000002_03797;MGYG000002528_01756;MGYG000001615_03374;MGYG000002312_00646;MGYG000001607_01064;MGYG000004667_03823 domain d__Bacteria 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia 0.22448979591836735 186801|Clostridia 0.9591836734693877 G 0.8571428571428571 Fructose-1,6-bisphosphate aldolase, class II 0.46938775510204084 fba 1.0 - 1.0 4.1.2.13 0.9795918367346939 ko:K01624 0.9795918367346939 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.9795918367346939 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 0.9795918367346939 RC00438,RC00439,RC00603,RC00604 0.9795918367346939 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_01876 0.02040816326530612 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.9795918367346939 0.9795918367346939 0.9795918367346939 0.9795918367346939 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.9795918367346939 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 0.9795918367346939 none 1.0 617036 0 240330 352797 617998 0 0 0 465982 460786 476496 0 0 822557 990317 337046 386103 4842424 707071 626023 0 0 1964452 0 0 374913 433213 1790607 446154 476204 69495 305041 198629 0 593676 0 422311 299909 113195 0 106659 0 199089 0 0 0 51249 56022 65359 0 0 289221 193244 0 240549 1585040 46949 51669 0 0 1347760 0 0 102357 111372 1616646 119855 250741 106594 139686 134019 0 102166 0 0 150558 1908894 0 2613806 871277 892324 0 0 0 1995135 1401122 952987 0 0 1671779 2061344 1389330 1245031 881512 1924513 2498778 0 0 1134126 0 0 1552150 795838 1269473 1919926 2817907 1063885 568343 1910518 0 1479395 0 2172330 963640 2691916 0 1710317 3421921 2338706 0 0 0 3502391 2227266 2419902 0 0 1810410 2361464 1514746 2091762 2156975 1467677 2565587 0 0 425057 0 0 1695254 1819212 3294700 4118064 2809379 2778255 2290942 2119087 0 2406615 0 2738543 2780217 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 186652 1334549 0 0 0 0 1719850 0 0 0 0 942460 0 3438 0 71530 0 0 34268 0 0 203573 +AAGIGNIHGKYPANWK MGYG000002517_00490;MGYG000000258_00162;MGYG000000233_01876;MGYG000001338_00333 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia 0.5 186801|Clostridia 1.0 G 0.75 Fructose-1,6-bisphosphate aldolase, class II 0.5 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00490 0.25 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822419 0 0 0 0 0 0 0 0 0 518230 0 0 0 0 0 0 0 0 0 0 424381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 377708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 169278 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1771740 0 0 0 0 0 0 0 0 0 2941102 0 0 0 0 0 0 0 0 0 0 1639932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIGNIHGVYPANWK MGYG000002545_01061;MGYG000003899_02090;MGYG000000193_00938;MGYG000002040_02084;MGYG000000022_00043 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3WGNI@541000|Ruminococcaceae 0.8 186801|Clostridia 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002545_01061 0.2 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 370138 0 0 0 0 0 0 0 0 579455 0 0 0 0 982850 0 0 0 0 572140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150310 0 0 0 0 0 0 0 0 1110548 0 0 0 0 1419023 0 0 0 0 1449291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522886 0 0 0 0 0 0 0 0 1935749 0 0 0 0 1878050 0 0 0 0 1505316 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 617980 0 0 0 0 0 0 0 0 0 0 0 0 0 763151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1414718 0 0 0 0 1368912 0 0 0 0 1452985 0 0 0 0 0 0 0 0 0 0 +AAGIIR MGYG000003022_00727 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella|s__Parasutterella sp000980495|m__MGYG000003022 1.0 COG0091@1|root,COG0091@2|Bacteria,1RH0W@1224|Proteobacteria,2VSE6@28216|Betaproteobacteria,1KM24@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 J 1.0 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome 1.0 rplV 1.0 - 1.0 - 1.0 ko:K02890 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L22 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003022_00727 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02890:RP-L22, MRPL22, rplV; large subunit ribosomal protein L22 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 614064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIKADALK MGYG000001410_02104;MGYG000003170_01495 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella 1.0 COG1053@1|root,COG1053@2|Bacteria,1QDYN@1224|Proteobacteria,2W8FG@28216|Betaproteobacteria,4PQFK@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 C 1.0 Glucose inhibited division protein A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001410_02104 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60736 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476452 0 0 0 497659 0 0 667062 0 0 0 0 0 0 0 0 371252 0 501686 0 0 0 0 0 0 678168 0 0 0 0 0 0 0 0 0 0 0 0 391015 0 0 0 548155 0 0 77816 0 0 0 0 0 0 0 0 0 0 72007 0 0 0 0 0 0 355301 0 0 0 0 0 0 0 0 0 0 0 0 606639 0 0 0 471592 0 0 960793 0 0 0 0 0 0 0 0 217375 0 258199 0 0 0 0 0 0 596138 0 0 0 0 0 0 0 +AAGILFAPESGEDTR MGYG000002478_04511;MGYG000002560_03419;MGYG000004797_02697 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4980@1|root,COG4980@2|Bacteria,4NXMW@976|Bacteroidetes,2FUB7@200643|Bacteroidia,4ARS7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG35214 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 YtxH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_04511 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 3494496 0 3144748 0 0 3342005 3883191 0 3857716 3283920 3264905 3633634 4383869 3642196 3382223 4698603 0 2327022 4265630 3295686 2977510 3008463 2902873 4551884 3202401 4112989 4258167 3118233 3244740 3856279 4031235 4084160 2794201 0 3583681 4662200 3614001 3175690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 968840 0 0 0 0 1822562 0 0 5420979 0 1256352 0 0 0 0 0 0 0 0 0 0 3230254 0 3451433 0 0 0 0 0 0 0 3578392 0 3432506 0 3093849 3799960 0 0 0 0 0 2550031 2822672 0 0 0 3012550 2774102 0 0 0 0 0 0 3242219 0 0 0 0 0 0 0 0 1056881 810276 0 877699 1191988 887961 0 0 903823 1055303 1080610 0 200427 1509774 789908 1434849 1011416 464893 739848 1148635 760197 1168579 0 1186259 1044601 670533 1098620 877323 0 1735424 1347958 1069802 801547 0 0 1461559 0 0 2387793 1619263 0 1910341 1585486 749221 1217233 3161916 1831769 1720257 2416805 0 5324027 2798924 3043786 1236757 1038496 4185443 2192092 2613287 2173292 3029066 4088549 2719698 1699349 0 1702246 1796691 0 2025331 1683579 1848503 2206485 +AAGIMLSAADRFK MGYG000000243_01876 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3669@1|root,COG3669@2|Bacteria,4NGKB@976|Bacteroidetes,2FM4I@200643|Bacteroidia,4AKD0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Alpha-N-acetylglucosaminidase 1.0 - 1.0 - 1.0 3.2.1.50 1.0 ko:K01205 1.0 ko00531,ko01100,ko04142,map00531,map01100,map04142 1.0 M00078 1.0 R07816 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 NAGLU,NAGLU_C,NAGLU_N 1.0 - 1.0 GH89 1.0 GH89 1.0 GH89 1.0 MGYG000000243_01876 1.0 alpha-N-acetylglucosaminidase. NAG. Hydrolyzes UDP-N-acetylglucosamine. Hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. 1.0 1.0 1.0 1.0 Glycosaminoglycan degradation|Metabolic pathways|Lysosome 1.0 K01205:NAGLU; alpha-N-acetylglucosaminidase [EC:3.2.1.50] 1.0 none 1.0 0 230807 258715 0 0 0 0 0 0 0 194653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 381507 0 0 0 0 258392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 87341 0 0 0 0 0 0 0 0 209054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73005 0 0 0 0 103638 0 226210 127226 0 0 0 0 0 0 0 55114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351543 0 0 0 0 159748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIMLWK MGYG000000003_00845 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia,22U5J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 T 1.0 histidine kinase DNA gyrase B 1.0 htpG 1.0 - 1.0 - 1.0 ko:K04079 1.0 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HATPase_c_3,HSP90 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_00845 1.0 - - - - 1.0 1.0 1.0 1.0 Protein processing in endoplasmic reticulum|PI3K-Akt signaling pathway|Necroptosis|Antigen processing and presentation|NOD-like receptor signaling pathway|Plant-pathogen interaction|IL-17 signaling pathway|Th17 cell differentiation|Progesterone-mediated oocyte maturation|Estrogen signaling pathway|Pathways in cancer|Prostate cancer|Fluid shear stress and atherosclerosis 1.0 K04079:HSP90A, htpG; molecular chaperone HtpG 1.0 none 1.0 0 0 0 0 0 0 0 0 1779464 0 0 0 0 0 905521 0 0 0 1846483 1451967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 535478 0 0 0 0 0 202571 0 0 0 409450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199889 0 0 0 0 0 170262 0 0 0 372374 349883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196308 0 0 0 0 0 0 0 0 0 329082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180840 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGINAETIDPAEAR MGYG000001313_00697 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0578@1|root,COG0578@2|Bacteria,4NJ15@976|Bacteroidetes,2FR3V@200643|Bacteroidia,4AQ69@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,DAO_C,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_00697 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGINPK MGYG000000074_00389 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,2FNBF@200643|Bacteroidia,22U65@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily 1.0 pheT 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 1.0 6.1.1.20 1.0 ko:K01890 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 B3_4,B5,FDX-ACB,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00389 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01890:FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 76429 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121609 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGINTASGKPN(Deamidated)K MGYG000003921_01311;MGYG000002040_00797;MGYG000002274_01728;MGYG000000022_00423;MGYG000001300_02638;MGYG000003166_01200 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WICR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 - 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_01311 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02867:RP-L11, MRPL11, rplK; large subunit ribosomal protein L11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490372 0 1061014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1759083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGINTASGKPNK MGYG000003921_01311;MGYG000002040_00797;MGYG000002274_01728;MGYG000000022_00423;MGYG000001300_02638;MGYG000003166_01200 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WICR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 - 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_01311 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02867:RP-L11, MRPL11, rplK; large subunit ribosomal protein L11 1.0 none 1.0 0 0 887779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4210020 0 0 0 0 97376 0 0 0 0 3630653 0 0 0 0 489153 0 0 0 0 590704 0 579784 513884 0 0 0 0 0 0 0 0 0 0 0 0 0 0 959001 0 0 0 0 1794105 0 0 0 0 1292617 0 0 0 0 664987 0 0 0 0 411340 0 266214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 609808 0 0 0 0 514712 0 0 0 0 573986 0 0 0 0 0 0 0 0 0 0 0 1635468 1769760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8749073 0 0 0 0 9267733 0 0 0 0 160064 0 0 0 0 1576305 0 0 0 0 2431619 0 0 61965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1971560 0 0 0 0 1489909 0 0 0 0 891667 0 0 0 0 0 0 0 0 0 118199 +AAGINTASGKPNKEK MGYG000002274_01728;MGYG000002040_00797;MGYG000001300_02638;MGYG000003166_01200 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WICR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 - 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_01728 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02867:RP-L11, MRPL11, rplK; large subunit ribosomal protein L11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 383533 570745 0 0 678488 0 0 0 512562 0 428419 0 0 0 599321 270050 0 0 0 0 469954 0 468109 0 0 359380 0 0 0 0 376819 0 0 0 0 399920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140115 0 0 0 0 69170 0 0 0 0 226114 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 123069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511763 0 0 0 0 596740 0 0 0 0 395245 0 0 0 0 0 0 0 0 0 147175 +AAGIPC(Carbamidomethyl)GTEVEVK MGYG000003266_00144;MGYG000004746_00559;MGYG000000188_00406;MGYG000003274_01389;MGYG000000802_00030;MGYG000001636_01240;MGYG000002065_00911 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1925@1|root,COG1925@2|Bacteria,2H0K7@201174|Actinobacteria,4CWQ1@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 PTS HPr component phosphorylation site 1.0 - 1.0 - 1.0 - 1.0 ko:K11189 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS-HPr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003266_00144 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K11189:- 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 320958 0 0 599967 226403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1911476 0 0 2019158 1711487 0 0 0 0 0 0 0 0 0 0 0 0 2679880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIPFGYHNHEMEFAK MGYG000002438_03917 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1082@1|root,COG1082@2|Bacteria,4NJF7@976|Bacteroidetes,2G2TH@200643|Bacteroidia,231JP@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Xylose isomerase-like TIM barrel 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03917 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190874 0 0 0 0 0 0 0 0 120654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468439 0 0 0 0 0 0 0 0 623163 0 0 0 0 0 0 0 0 +AAGIPSLFMINK MGYG000004748_03039;MGYG000003533_02153;MGYG000000273_00707;MGYG000002614_01013;MGYG000001750_00508;MGYG000001789_00556;MGYG000000224_02142;MGYG000000042_01813;MGYG000000043_01365;MGYG000001313_01608;MGYG000001378_00878;MGYG000004479_02542;MGYG000001661_00715;MGYG000002478_03492;MGYG000001835_00920;MGYG000000415_00521;MGYG000001345_02954;MGYG000002007_01215;MGYG000003693_02501;MGYG000003351_05093;MGYG000000243_02912;MGYG000000196_04594;MGYG000001599_02528;MGYG000002203_01208;MGYG000004797_00255 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,2FM5R@200643|Bacteroidia,4APTB@815|Bacteroidaceae 0.88 976|Bacteroidetes 1.0 J 1.0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) 1.0 ileS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.5 1.0 ko:K01870 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03656 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,DUF559,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004748_03039 0.04 isoleucine--tRNA ligase. isoleucyl-tRNA synthetase. - ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01870:IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5] 1.0 none 1.0 674485 0 1707077 731298 1267774 695628 634845 707077 667026 559024 1068233 570958 1213969 493408 591257 1008427 744974 0 527218 289460 0 418195 224669 626942 315473 547287 783805 324896 0 720394 1222145 0 1882205 0 0 721956 577138 1515443 527621 0 698615 651747 873466 629170 701649 691136 607455 785117 1143719 635460 1201527 875705 622902 1124498 612724 906204 606811 826018 0 799815 1326193 477918 708667 559342 631190 881919 0 478057 531865 0 657456 0 0 567109 587768 569945 363893 0 359241 0 705533 600112 477420 381647 320753 402813 643191 552568 920690 306768 266647 677805 375344 759299 292385 431183 0 134960 439912 333565 370359 245102 265347 351001 0 364975 549530 0 119523 0 0 443172 399095 286207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1408123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273915 1212561 0 0 0 0 0 0 0 0 0 0 +AAGIPSLFMINKK MGYG000004479_02542;MGYG000002478_03492;MGYG000004797_00255 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0060@1|root,COG0060@2|Bacteria,4NEYT@976|Bacteroidetes,2FM5R@200643|Bacteroidia,4APTB@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) 1.0 ileS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.5 1.0 ko:K01870 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03656 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,DUF559,tRNA-synt_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004479_02542 0.3333333333333333 isoleucine--tRNA ligase. isoleucyl-tRNA synthetase. - ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01870:IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316988 0 0 0 0 425811 0 0 0 0 326916 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152847 0 0 0 0 0 0 0 0 0 73880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335182 0 0 0 0 285229 0 0 0 0 310618 0 0 0 0 0 0 0 0 0 0 +AAGITAVVFDR MGYG000001292_02346 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG0256@1|root,COG0256@2|Bacteria,2IKTX@201174|Actinobacteria,4D0WE@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001292_02346 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4269894 0 0 0 0 1356004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 176444 0 0 0 0 0 0 0 0 0 0 +AAGITMDPR MGYG000000080_03187 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DAO,FAD_binding_2,FAD_oxidored,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_03187 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4847540 0 0 0 0 0 0 0 0 0 +AAGIVDGYGN(Deamidated)GTFGGDR MGYG000004769_01190 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG3203@1|root,COG3203@2|Bacteria,1V1RK@1239|Firmicutes,4H431@909932|Negativicutes 1.0 909932|Negativicutes 1.0 M 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Porin_4,Porin_5,SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01190 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGIVGMGGAGFPTGVK MGYG000002279_01084;MGYG000002992_00601;MGYG000000038_01565 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24AN3@186801|Clostridia,27WHN@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 RnfC Barrel sandwich hybrid domain 1.0 prdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,RnfC_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_01084 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 562757 0 0 0 0 0 0 0 0 0 0 761307 549391 0 0 818734 988302 0 0 0 0 820323 0 0 0 0 0 0 0 0 288504 0 0 0 0 0 0 0 1241158 0 0 0 0 0 0 0 0 0 0 738476 400901 0 0 865068 1110574 0 0 0 0 930248 0 0 0 0 0 0 0 0 615361 0 0 0 0 0 0 0 1505256 0 0 0 0 0 0 0 0 0 0 1099051 904336 0 0 1640676 1484732 0 0 0 0 1264828 0 0 0 0 0 0 0 0 1011054 0 0 0 0 0 0 0 448037 0 0 0 0 0 0 0 0 0 0 236731 991919 0 0 523455 405512 0 0 0 0 482989 0 0 0 0 0 0 0 0 383578 0 0 0 0 0 0 0 1099274 0 0 0 0 0 0 0 0 0 0 865170 650614 0 0 786284 538293 0 0 0 0 511307 0 0 0 0 0 0 0 0 529901 0 0 0 0 +AAGIYVK MGYG000000223_01704 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,3VPMI@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 pyridine nucleotide-disulfide oxidoreductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_01704 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1156386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3078167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92129 0 0 0 0 0 0 0 0 0 +AAGKDPFEITTYEQGIHAAEIK MGYG000002052_00057 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum|s__|m__MGYG000002052 1.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family 1.0 lysS 1.0 - 1.0 6.1.1.6 1.0 ko:K04567 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03658 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DUF2156,tRNA-synt_2,tRNA-synt_2_TM,tRNA_anti-codon,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002052_00057 1.0 lysine--tRNA ligase. lysyl-tRNA synthetase. - ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K04567:KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1087971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGKKEDIVVR MGYG000004271_00657 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG0451@1|root,COG0451@2|Bacteria,1TQW7@1239|Firmicutes,24BI6@186801|Clostridia 1.0 186801|Clostridia 1.0 M 1.0 CDP-glucose 4,6-dehydratase 1.0 rfbG 1.0 - 1.0 4.2.1.45 1.0 ko:K01709 1.0 ko00520,map00520 1.0 - 1.0 R02426 1.0 RC00402 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 GT9 1.0 MGYG000004271_00657 1.0 CDP-glucose 4,6-dehydratase. - - CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H2O. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 K01709:rfbG; CDP-glucose 4,6-dehydratase [EC:4.2.1.45] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGKPNFYMFGEIC(Carbamidomethyl)TR MGYG000000258_01904 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Ruminococcus_E|s__Ruminococcus_E bromii_B|m__MGYG000000258 1.0 COG0366@1|root,COG3291@1|root,COG0366@2|Bacteria,COG3291@2|Bacteria,1V0U1@1239|Firmicutes,24ZQ4@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Alpha amylase, catalytic domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Alpha-amylase,CBM26,CHB_HEX_C_1 1.0 3.2.1.1|3.2.1.98 1.0 GH13_42 1.0 CBM26+GH13+CBM35+CBM25 1.0 GH13_42 1.0 MGYG000000258_01904 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 619851 0 0 0 0 1015088 0 0 0 0 753825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGL(Xle->Met)AEDAAADEPLDFK MGYG000000074_02028 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG2968@1|root,COG2968@2|Bacteria,4NVTG@976|Bacteroidetes,2G3CT@200643|Bacteroidia,22UK1@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Protein of unknown function (DUF541) 1.0 - 1.0 - 1.0 - 1.0 ko:K09807 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 SIMPL 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02028 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K09807:K09807; uncharacterized protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1027744 0 0 0 0 0 0 0 0 +AAGLDAIHDTVHEM(Oxidation)AR MGYG000004681_00940;MGYG000002961_00635;MGYG000000255_00995;MGYG000003266_00666;MGYG000001642_01559;MGYG000002775_00760 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,2HUEX@201174|Actinobacteria,4CUC5@84998|Coriobacteriia 0.8333333333333334 84998|Coriobacteriia 0.8333333333333334 C 1.0 Rubrerythrin 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004681_00940 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 4855522 0 0 0 0 0 441728 0 0 0 0 0 0 0 1720545 0 1573627 0 0 0 0 951687 0 0 0 0 432706 0 0 0 0 0 0 0 4736819 0 0 0 1409061 0 0 0 0 0 1450055 0 0 0 0 0 0 0 855781 0 2613978 0 0 0 0 1784986 0 0 0 0 584359 0 0 0 0 0 0 0 0 0 0 0 377928 0 0 0 0 0 726162 0 0 0 0 0 0 0 944890 0 0 0 0 0 0 0 0 0 0 0 206940 0 0 0 0 0 0 0 0 0 0 0 594815 0 0 0 0 0 0 0 0 0 0 0 0 0 735399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446237 0 250843 0 0 0 0 315143 0 0 0 0 2958973 0 0 0 0 0 0 0 204293 0 0 +AAGLDAIHDTVHEMAR MGYG000004681_00940;MGYG000002961_00635;MGYG000000255_00995;MGYG000003266_00666;MGYG000001642_01559;MGYG000002775_00760 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,2HUEX@201174|Actinobacteria,4CUC5@84998|Coriobacteriia 0.8333333333333334 84998|Coriobacteriia 0.8333333333333334 C 1.0 Rubrerythrin 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004681_00940 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 361664 0 493127 0 0 0 0 0 0 0 0 988589 0 0 0 0 1107320 0 0 0 0 745343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353577 0 410067 0 0 0 0 0 0 0 0 1435974 0 0 0 0 859119 0 0 0 0 971731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 318225 0 423609 0 0 0 0 0 0 0 0 513486 0 0 0 0 667866 0 0 0 0 823235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254999 0 292922 0 0 0 0 0 0 0 0 758342 0 0 0 0 0 0 0 0 0 530220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270693 0 60504 0 0 0 0 0 0 0 0 445826 0 0 0 0 589124 0 0 0 0 739176 0 0 0 0 0 0 0 0 0 0 +AAGLDAIHDTVHEMARDEAR MGYG000004681_00940;MGYG000002961_00635;MGYG000000255_00995;MGYG000003266_00666;MGYG000001642_01559;MGYG000002919_00508;MGYG000002775_00760 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,2HUEX@201174|Actinobacteria,4CUC5@84998|Coriobacteriia 0.8571428571428571 84998|Coriobacteriia 0.8571428571428571 C 1.0 Rubrerythrin 1.0 - 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubrerythrin 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004681_00940 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLDAIR MGYG000000271_03312;MGYG000004271_02207 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG4284@1|root,COG4284@2|Bacteria,1TQUD@1239|Firmicutes,24A8D@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.7.7.23,2.7.7.83 1.0 ko:K00972 1.0 ko00520,ko01100,ko01130,map00520,map01100,map01130 1.0 M00361,M00362 1.0 R00416 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 UDPGP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_03312 0.5 UDP-N-acetylglucosamine diphosphorylase. | UDP-N-acetylgalactosamine diphosphorylase. UDP-N-acetylglucosamine pyrophosphorylase. Part of the pathway for acetamido sugar biosynthesis in bacteria and archaea.-!-The enzyme from several bacteria (e.g., Escherichia coli, Bacillus subtilis and Haemophilus influenzae) has been shown to be bifunctional and also to possess the activity of EC 2.3.1.157.-!-The enzyme from plants and animals is also active toward N-acetyl- alpha-D-galactosamine 1-phosphate (cf. EC 2.7.7.83), while the bacterial enzyme shows low activity toward that substrate. | The enzyme from plants and animals also has activity toward N-acetyl- alpha-D-glucosamine 1-phosphate (cf. EC 2.7.7.23). H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine. | H(+) + N-acetyl-alpha-D-galactosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-galactosamine. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K00972:UAP1; UDP-N-acetylglucosamine/UDP-N-acetylgalactosamine diphosphorylase [EC:2.7.7.23 2.7.7.83] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLDP(Pro->Val)YK MGYG000000029_00187 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides finegoldii|m__MGYG000000029 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000029_00187 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6185545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLDSPFEEGTIGK MGYG000004735_00112 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,2495D@186801|Clostridia,3XZPT@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 oligoendopeptidase, M3 family 1.0 pz-A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Peptidase_M3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00112 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLDVYADEPATNK MGYG000002794_01059;MGYG000001733_00763;MGYG000004487_01856;MGYG000004475_00746;MGYG000003819_01257;MGYG000001824_00899;MGYG000002156_00958 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,2N6Y5@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 EH 1.0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 1.0 serA 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_01059 0.14285714285714285 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1.0 none 1.0 1395757 731545 575840 0 555835 0 1409944 0 0 0 0 0 0 0 0 0 0 0 0 912469 0 0 0 0 0 951506 888816 0 0 0 0 460246 802269 864834 0 988548 610082 761355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 265843 1062177 1118688 0 568964 0 447520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 816592 958679 434950 0 518134 0 1179357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLDVYK MGYG000001310_00612;MGYG000000249_02372;MGYG000000251_02115;MGYG000002286_00349 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_00612 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1318326 0 1664013 0 1672865 3560638 1593737 1754063 1481085 1433351 1679033 5950367 2399995 291988 0 2155252 1212806 4901454 0 441134 0 4174165 4722583 1843842 0 1840982 1149997 4627490 1270647 1517845 1801056 357850 1649145 536948 1584283 261051 1621060 1955043 2451367 0 2402168 0 2314439 1127256 2143422 1884664 1822734 1567436 1581176 4426467 2209522 1351646 0 1739094 5875143 5946288 0 2186520 0 838761 5876919 1738542 0 1823491 2048124 5086359 2426370 0 3951205 2057989 2612735 2534952 2395945 2577822 2141084 2981113 3920973 0 4105598 0 3124948 3691167 3830451 4113812 4468836 4157148 2785991 3114843 3038026 3918071 0 3736343 3832858 4071101 0 3021172 0 3437300 6090738 3792972 0 3808630 3603707 7403788 4466800 4195250 3398265 3675759 3042940 4234062 4156508 3668163 3459000 3440816 2064872 0 3773854 0 2627363 2852230 2731094 3149218 2682975 3318958 2984771 2582845 2478033 2277061 0 2115957 3114459 0 0 489588 0 2448369 8645991 2929562 0 3136388 2153262 0 2437431 2730977 2229499 3148235 497580 4000343 3257230 707893 2619018 3595941 383335 0 712233 0 274938 356862 556667 537282 214383 310527 207534 1033754 128856 582978 0 451098 507626 2016721 0 386942 0 190849 2807817 230605 0 0 492140 3661944 260223 0 284790 425828 1003314 491607 146207 195714 191308 580938 +AAGLEAAK MGYG000002469_01727;MGYG000003383_00235;MGYG000001292_02316;MGYG000002469_00420;MGYG000003683_01099 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0120@1|root,COG0120@2|Bacteria,2GMHW@201174|Actinobacteria,4CZDH@85004|Bifidobacteriales 0.8 201174|Actinobacteria 1.0 G 0.8 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate 0.8 rpiA 0.8 - 0.8 5.3.1.6 0.8 ko:K01807 0.8 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.8 M00004,M00007,M00165,M00167,M00580 0.8 R01056 0.8 RC00434 0.8 ko00000,ko00001,ko00002,ko01000 0.8 - 1.0 - 1.0 - 1.0 Rib_5-P_isom_A 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002469_01727 0.2 ribose-5-phosphate isomerase. ribose phosphate isomerase. Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate. aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate. 0.8 0.8 0.8 0.8 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.8 K01807:rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6] 0.8 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1675501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1430391 0 0 0 0 1214385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2201448 0 0 0 0 702124 0 0 0 0 1590695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLENLK MGYG000001652_01650 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__V9D3004|s__V9D3004 sp002349525|m__MGYG000001652 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,27I98@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001652_01650 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Vitamin B6 metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00831:serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1678694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3452628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802757 0 0 0 0 0 0 +AAGLLAK MGYG000004763_00962 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG0578@1|root,COG0578@2|Bacteria,4NJ15@976|Bacteroidetes,2FR3V@200643|Bacteroidia,4AQ69@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,DAO_C,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004763_00962 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLLDNPVK MGYG000004468_01043;MGYG000001337_02760;MGYG000002108_01347;MGYG000000243_01631;MGYG000003493_02044;MGYG000000074_00316;MGYG000002478_03834;MGYG000001789_00906;MGYG000003202_00717 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0112@1|root,COG0112@2|Bacteria,4NE30@976|Bacteroidetes,2FM07@200643|Bacteroidia,4AM56@815|Bacteroidaceae 0.4444444444444444 976|Bacteroidetes 1.0 E 1.0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism 1.0 glyA 1.0 - 1.0 2.1.2.1 1.0 ko:K00600 1.0 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 1.0 M00140,M00141,M00346,M00532 1.0 R00945,R09099 1.0 RC00022,RC00112,RC01583,RC02958 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 SHMT 1.0 - 1.0 - 1.0 - 1.0 GH13_11 0.8888888888888888 MGYG000004468_01043 0.1111111111111111 glycine hydroxymethyltransferase. threonine aldolase. Also catalyzes the reaction of glycine with acetaldehyde to form L-threonine, and with 4-trimethylammoniobutanal to form 3-hydroxy- N(6),N(6),N(6)-trimethyl-L-lysine. (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)- 5,6,7,8-tetrahydrofolate + L-serine. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Cyanoamino acid metabolism|Glyoxylate and dicarboxylate metabolism|One carbon pool by folate|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|Antifolate resistance 1.0 K00600:glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1] 1.0 none 1.0 1575859 0 1924110 1268599 0 0 1574685 1375213 1183593 1085921 1106991 1437680 0 1164739 0 1495566 0 1189786 1485762 1425291 0 0 1459581 0 0 1186535 0 1422584 0 1394394 1610264 0 1707756 1356670 0 0 1377037 1792113 1443467 0 1318933 1262448 0 0 1130757 0 1514862 998771 1304427 1125731 0 1130430 0 1212157 0 1247639 1130030 1099588 0 0 2097264 0 0 1137377 0 1926114 0 1281749 828869 0 1479504 1258615 0 0 1355501 1210267 372890 0 209592 755226 0 0 580775 362353 679328 383196 562849 455032 0 635704 0 508440 0 791886 440384 516067 0 0 665195 0 0 425366 0 645506 0 600242 688996 0 456595 542651 0 0 355471 737684 891612 0 408811 456599 0 0 629365 660518 0 542404 492454 398621 0 585567 0 755202 0 188438 626152 408510 0 0 278402 0 0 361874 0 336016 0 373673 199790 0 483740 340413 0 0 598132 325334 873582 0 1142887 864534 0 0 796384 1118256 971897 481375 580197 813046 0 523278 0 957024 0 1596465 1247289 1152419 0 0 1520205 0 0 801590 0 1821421 0 1205192 912917 0 563068 985931 0 0 712872 857674 +AAGLLER MGYG000004735_02408 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,21ZF0@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 - 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_02408 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLLGK MGYG000000098_02464 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides bouchesdurhonensis|m__MGYG000000098 1.0 COG0578@1|root,COG0578@2|Bacteria,4NJ15@976|Bacteroidetes,2FR3V@200643|Bacteroidia,4AQ69@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,DAO_C,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000098_02464 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 643257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 598638 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLLQR MGYG000002494_03827;MGYG000002515_00885;MGYG000002534_03362;MGYG000003022_01866 class d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria 1.0 COG0578@1|root,COG0578@2|Bacteria,1MUMY@1224|Proteobacteria,1RUEK@1236|Gammaproteobacteria,3XMZ8@561|Escherichia 0.75 1236|Gammaproteobacteria 0.75 C 1.0 Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor 0.75 glpA 0.75 GO:0000166,GO:0003674,GO:0003824,GO:0004368,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006072,GO:0006091,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016901,GO:0019637,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046168,GO:0046434,GO:0048037,GO:0050660,GO:0050662,GO:0052646,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901136,GO:1901265,GO:1901363,GO:1901575 0.75 1.1.5.3 0.75 ko:K00111 0.75 ko00564,ko01110,map00564,map01110 0.75 - 1.0 R00848 0.75 RC00029 0.75 ko00000,ko00001,ko01000 0.75 - 1.0 - 1.0 iSDY_1059.SDY_2436 0.75 DAO,Fer2_BFD 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03827 0.25 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 0.75 0.75 0.75 0.75 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 0.75 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1538572 0 0 0 0 1935910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLPVDGK MGYG000000182_01779 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Mitsuokella|s__Mitsuokella sp003458855|m__MGYG000000182 1.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H21V@909932|Negativicutes 1.0 909932|Negativicutes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 - 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000182_01779 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03043:rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 173395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166596 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 118353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 716039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLQVNM(Oxidation)VSAQPGSGSNFR MGYG000000243_01882 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4AWF7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01882 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLQVNMVSAQPGSGSNFR MGYG000000243_01882 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4AWF7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01882 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 801552 0 638161 0 0 701500 0 0 0 0 0 594370 0 0 683541 751910 0 0 0 0 0 0 0 0 0 0 0 0 0 824237 0 0 0 0 572433 0 0 0 0 0 267536 0 0 174424 0 0 0 0 0 107969 0 0 341950 269260 0 0 0 0 0 0 0 0 0 0 0 0 0 535863 0 0 0 0 321716 0 0 0 346693 0 0 0 0 0 0 0 0 0 0 441662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 206299 0 0 0 0 0 0 0 0 0 0 194337 0 0 0 0 0 0 0 0 0 0 0 512020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLSFGEAK MGYG000002494_00473 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0760@1|root,COG0760@2|Bacteria,1MWV0@1224|Proteobacteria,1RMT5@1236|Gammaproteobacteria,3WVJB@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 O 1.0 SurA N-terminal domain 1.0 ppiD 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 1.0 5.2.1.8 1.0 ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00473 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K03770:ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 458113 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212886 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1166745 1218392 0 938138 1446670 1058830 0 0 0 0 0 0 0 0 0 0 0 1526783 0 1290675 1675718 0 1305148 1228944 0 0 0 1869242 1207795 0 828931 1166767 0 0 0 0 1110613 0 531281 0 0 0 0 506551 0 0 0 0 0 0 0 0 0 0 0 575682 0 495541 508104 0 0 304037 0 0 0 318098 466017 0 539015 285948 0 0 0 0 598890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272291 0 308218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577415 581305 699134 0 0 0 0 0 0 0 0 0 0 0 225812 0 656099 582173 0 373294 627676 0 0 0 758582 0 0 860766 901224 0 0 0 0 597186 +AAGLSVTPTTAAPSAPK MGYG000001302.1_01546 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG4770@1|root,COG4770@2|Bacteria,4NSWV@976|Bacteroidetes,2FRYI@200643|Bacteroidia,22UGJ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Biotin-requiring enzyme 1.0 mmdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_01546 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGLYK MGYG000000053_00539;MGYG000000222_02092;MGYG000000074_02214;MGYG000001302.1_01771;MGYG000002082_02095;MGYG000001783_01717;MGYG000002517_02258;MGYG000002478_01473;MGYG000004797_02540;MGYG000002438_03363;MGYG000001489_04121 domain d__Bacteria 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FN0E@200643|Bacteroidia,22WXW@171551|Porphyromonadaceae 0.45454545454545453 976|Bacteroidetes 0.9090909090909091 H 0.9090909090909091 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA 0.9090909090909091 kbl 0.9090909090909091 - 1.0 2.3.1.29 0.9090909090909091 ko:K00639 0.9090909090909091 ko00260,map00260 0.9090909090909091 - 0.9090909090909091 R00371 0.9090909090909091 RC00004,RC00394 0.9090909090909091 ko00000,ko00001,ko01000,ko01007 0.9090909090909091 - 1.0 - 1.0 - 1.0 Aminotran_1_2 0.9090909090909091 - 1.0 - 1.0 - 1.0 - 0.9090909090909091 MGYG000000053_00539 0.09090909090909091 glycine C-acetyltransferase. 2-amino-3-ketobutyrate coenzyme A ligase. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Glycine, serine and threonine metabolism 0.9090909090909091 K00639:kbl, GCAT; glycine C-acetyltransferase [EC:2.3.1.29] 0.9090909090909091 none 1.0 493330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 910216 833137 0 778435 789345 1092086 0 0 0 0 0 918533 0 0 663470 394714 935464 0 0 0 0 0 0 0 826966 689638 0 0 0 0 0 0 0 0 1039922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163815 0 457651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1043674 710294 1416554 1761535 0 1233507 1079162 0 1081633 1161092 1617711 0 0 0 983205 1041729 0 1033916 0 1687750 0 0 1283219 964345 1217361 0 0 0 0 1014851 530248 921114 0 2385198 1101446 0 0 +AAGLYKNER MGYG000000222_02092;MGYG000001302.1_01771;MGYG000001783_01717;MGYG000002478_01473;MGYG000004797_02540;MGYG000002438_03363;MGYG000003701_03757;MGYG000001489_04121;MGYG000000174_02073 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FN0E@200643|Bacteroidia,22WXW@171551|Porphyromonadaceae 0.7777777777777778 976|Bacteroidetes 1.0 H 1.0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA 1.0 kbl 1.0 - 1.0 2.3.1.29 1.0 ko:K00639 1.0 ko00260,map00260 1.0 - 1.0 R00371 1.0 RC00004,RC00394 1.0 ko00000,ko00001,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000222_02092 0.1111111111111111 glycine C-acetyltransferase. 2-amino-3-ketobutyrate coenzyme A ligase. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism 1.0 K00639:kbl, GCAT; glycine C-acetyltransferase [EC:2.3.1.29] 1.0 none 1.0 693771 0 1159963 817048 1253953 859647 0 331119 805410 0 878420 858497 1238120 1350394 719175 1076195 840310 1355054 1250969 709422 1044392 1228533 728896 1270859 690413 891999 940418 839319 0 803964 1123282 1142093 1217431 377178 956273 783708 749560 1245286 318719 0 726938 556367 549613 440555 0 384561 299325 0 520103 410006 421028 329370 707453 371729 317992 940578 265789 126067 518650 621335 183344 447162 438634 412408 191619 133081 0 313538 445501 619518 625362 510222 531022 533816 478323 399753 77114 0 485047 562801 658909 737171 0 212233 530757 0 492864 613311 324691 296444 291598 303626 291312 222556 589587 503647 598594 453057 693434 846349 505914 187877 237582 723944 0 246749 700367 445989 357612 158421 267022 691913 454065 421283 365261 0 134960 469226 153895 409517 0 276482 174321 0 355993 751901 114144 464099 524524 156881 173631 276967 502051 449791 355940 194840 350928 413859 353795 469296 324946 324121 0 386489 362305 524586 277351 350034 263060 358435 117772 202985 651859 0 712919 1154453 1587820 773195 0 526410 797630 0 965333 1176364 1282970 1002260 725341 645029 558567 474805 664783 732651 511113 524607 364991 1065917 943709 974227 663804 464194 0 1204208 1064798 1029603 899684 787496 937028 995455 1810899 694476 +AAGMAAESAAR MGYG000003683_01113;MGYG000003730_00226;MGYG000002469_01744;MGYG000001292_02337;MGYG000003383_00196 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,4D0PJ@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01113 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472397 0 0 0 0 992005 0 0 0 0 643097 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9950223 0 0 0 0 4101899 0 0 0 0 7145320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2133312 0 0 0 0 1267396 0 0 0 0 1386165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1221668 0 0 0 0 1468305 0 0 0 0 1014882 0 0 0 0 0 0 0 0 0 0 +AAGMISN(Deamidated)DEIAAMKR MGYG000002556_00558 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-279|s__CAG-279 sp000437795|m__MGYG000002556 1.0 COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,2FNRM@200643|Bacteroidia,22WNF@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB,SusF_SusE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002556_00558 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 149474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 911280 0 0 0 0 925131 0 0 0 0 821255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 101299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGN(Deamidated)NGLWEVTVALK MGYG000002478_01081;MGYG000002560_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01081 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 680734 0 0 0 0 772807 0 0 0 0 1189808 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409390 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGNADIIGVGFDK MGYG000000201_01306 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066145|m__MGYG000000201 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQ95@1239|Firmicutes,24AX7@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 PFAM periplasmic binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K10439 1.0 ko02010,ko02030,map02010,map02030 1.0 M00212 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.1,3.A.1.2.13,3.A.1.2.19 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_01306 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10439:rbsB; ribose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1195440 0 0 0 0 490467 0 0 0 0 1237357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 274578 0 0 0 0 320621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 970076 0 0 0 0 881496 0 0 0 0 804144 0 0 0 0 0 0 0 0 0 0 +AAGNEADAEVAAK MGYG000001346_03032 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1271@1|root,COG1271@2|Bacteria,4NG7U@976|Bacteroidetes,2FMV6@200643|Bacteroidia,4AK8I@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1271 Cytochrome bd-type quinol oxidase, subunit 1 1.0 cydA 1.0 - 1.0 1.10.3.14 1.0 ko:K00425 1.0 ko00190,ko01100,ko02020,map00190,map01100,map02020 1.0 M00153 1.0 R11325 1.0 RC00061 1.0 ko00000,ko00001,ko00002,ko01000 1.0 3.D.4.3 1.0 - 1.0 - 1.0 Cyt_bd_oxida_I 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_03032 1.0 ubiquinol oxidase (electrogenic, proton-motive force generating). cytochrome bd-I oxidase. This terminal oxidase enzyme is unable to pump protons but generates a proton motive force by transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water.-!-The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) is 1.-!-The bd-I oxidase from the bacterium Escherichia coli is the predominant respiratory oxygen reductase that functions under microaerophilic conditions in that organism. cf. EC 7.1.1.3.-!-Formerly EC 1.10.3.14. 2 a ubiquinol + 4 H(+)(in) + O2(in) = 2 a ubiquinone + 4 H(+)(out) + 2 H2O(in). 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways|Two-component system 1.0 K00425:cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 288765 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 457441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 749340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 152124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGNN(Deamidated)GLWEVTVALK MGYG000002478_01081;MGYG000002560_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01081 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2991365 3922355 2911221 3965537 4131968 0 2864439 0 3158035 2934223 0 0 4974419 2659980 0 2391833 2922339 2118524 0 4119083 3021857 0 3107763 0 2881854 0 3360565 4474605 3321806 0 0 6078024 3458627 0 3966244 0 3404145 3493831 0 0 169802 0 0 0 282735 0 344219 4825965 0 0 0 585917 0 0 0 0 277455 0 0 0 0 0 0 402912 0 143985 117268 0 0 314946 0 0 0 0 0 261526 461972 359110 548654 109047 884558 0 618148 0 0 947479 0 0 1434628 590483 0 1011151 416776 432646 1198241 1018617 702343 0 614034 0 587731 1289602 934609 1134424 577527 0 0 1198033 716347 0 1003893 0 1031830 528790 439326 214314 0 158649 0 0 97003 0 0 428711 0 0 239019 238586 0 116851 0 175008 0 0 0 0 0 0 304506 261620 248130 0 198686 0 0 0 239083 0 0 0 200167 0 0 0 0 200285 0 0 0 0 4845441 0 0 0 0 26513053 0 7771145 2685387 0 0 0 0 0 14628739 0 0 0 0 5537924 0 0 0 0 0 0 0 0 57440069 0 +AAGNNGLW(Dioxidation)EVTVALK MGYG000002478_01081;MGYG000002560_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01081 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 587248 0 0 0 0 0 0 0 0 0 0 1267686 1184348 0 0 649626 888168 561293 460847 0 0 0 293684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360700 0 0 0 0 242754 0 257243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 202170 0 0 0 0 0 0 0 0 0 0 0 210275 0 0 0 268979 0 307340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGNNGLW(Trp->Kynurenin)EVTVALK MGYG000002478_01081;MGYG000002560_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01081 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1279295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1188572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGNNGLWEVTVALK MGYG000002478_01081;MGYG000002560_04324 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1196@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01081 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 3381228 3838210 3720044 5679295 5641627 3365210 4784967 0 4555335 3558057 0 0 5713475 2863175 0 3803780 4468066 2472837 3324055 3404349 3788452 3487579 3797702 4197556 3110513 3498824 4239405 3786765 4814263 6136921 0 4013768 4054349 0 4778514 4478441 4494995 3979617 0 633042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300965 0 0 0 0 0 0 0 0 0 0 0 0 0 1102820 761308 479351 766688 1314492 1048363 872133 0 364296 896778 0 0 1259838 994661 0 1349832 729317 1042983 1224346 1367218 1318277 874781 1137204 694558 901323 1552030 1236108 1395231 1114205 1100442 0 889068 1175963 0 1336524 1000205 323406 622238 48394 496118 0 69133 56511 0 0 0 61917 42037 0 0 0 126579 0 0 94671 0 60985 73253 0 0 0 0 70663 126690 0 0 0 0 0 309808 0 0 59805 137577 0 138334 0 0 0 0 0 0 222344 0 0 0 0 0 0 0 0 41084 0 268658 0 0 0 0 388345 0 0 0 0 0 0 0 0 375902 189931 0 0 0 0 164686 +AAGNQAELDEK MGYG000000074_00484 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0111@1|root,COG0111@2|Bacteria,4PMZ0@976|Bacteroidetes,2G0M0@200643|Bacteroidia,22V4Q@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family 1.0 - 1.0 - 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 2-Hacid_dh,2-Hacid_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00484 1.0 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGPAAAG(Gly->Gln)AAAEEK MGYG000003202_00136 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__UBA3263|s__UBA3263 sp900759865|m__MGYG000003202 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003202_00136 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGPAAAGAAAAEEK MGYG000001364_00555;MGYG000001306_02652;MGYG000004479_00848;MGYG000003693_02794;MGYG000000043_02878 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001364_00555 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 324123 0 151489 0 240982 0 0 0 0 0 231280 0 0 0 0 0 0 232984 0 249002 0 0 386194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 866877 0 904194 1068061 1002254 0 0 1027886 1242256 0 1709854 773620 749771 1003677 815424 0 0 6863899 0 619614 0 0 0 0 0 1027384 858548 0 0 0 0 0 845388 0 0 859345 0 0 0 0 836694 504531 0 0 0 602735 897402 0 0 545864 573619 551485 622683 0 0 279950 0 0 0 0 257818 0 0 745126 0 169672 0 0 0 0 0 0 0 0 0 685448 906882 0 0 0 191088 0 0 266528 0 0 0 278855 0 187249 706687 0 0 990545 0 0 0 0 1003663 0 0 795202 162975 627761 0 0 0 0 887482 0 0 0 1019297 114872 0 0 369404 423561 229386 0 0 354566 274033 0 530795 0 517979 0 105853 0 0 2136485 0 231866 0 0 2188193 0 0 219643 0 1441731 0 0 0 0 456125 0 0 445665 155990 370789 +AAGPAAAGAAAEEK MGYG000003202_00136 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__UBA3263|s__UBA3263 sp900759865|m__MGYG000003202 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003202_00136 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGPAAAGAAAEEKTSFDVVLK MGYG000003202_00136 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__UBA3263|s__UBA3263 sp900759865|m__MGYG000003202 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,1I1Y0@117743|Flavobacteriia 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003202_00136 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1553914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212805 0 0 0 0 0 0 0 0 282302 0 0 227442 0 0 0 0 0 0 0 770960 0 0 0 0 0 0 0 0 0 0 749606 0 0 0 0 0 0 0 786330 0 0 0 0 0 1021276 0 0 0 0 0 594049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 758090 0 0 576697 0 0 0 0 0 0 340568 0 0 0 466537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1215674 0 901029 0 0 1235197 0 1312417 792353 834248 1249407 0 0 0 0 0 0 0 2027428 1027217 1726933 0 +AAGPAAAGAAVEEK MGYG000001666_00327 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-873|s__|m__MGYG000001666 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001666_00327 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 2987489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1810530 0 0 0 0 0 0 0 2037302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 930996 0 0 0 0 1738221 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGPAAAGAVAEEK MGYG000002820_00704 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Negativicoccaceae|g__Negativicoccus|s__Negativicoccus sp900556745|m__MGYG000002820 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4H4X8@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002820_00704 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1795220 1520827 0 0 0 0 0 0 1466737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1299142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGPAAAGGAAAEEK MGYG000003363_00507 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900766195|m__MGYG000003363 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003363_00507 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGPAAAGGAAAEEKTSFDVVLK MGYG000003363_00507 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp900766195|m__MGYG000003363 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003363_00507 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 410268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 898761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGPAAFVTK MGYG000002517_01802 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 O-acetylhomoserine 1.0 metY 1.0 - 1.0 2.5.1.49 1.0 ko:K01740 1.0 ko00270,ko01100,map00270,map01100 1.0 - 1.0 R01287,R04859 1.0 RC00020,RC02821,RC02848 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01802 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways 1.0 K01740:metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] 1.0 none 1.0 976391 0 383715 0 152559 187488 0 307899 0 0 0 0 0 353201 432165 0 212210 0 0 384966 0 574287 0 126469 0 0 0 0 0 276313 0 0 0 267777 498587 867428 788953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7651053 0 0 8226092 383432 0 1678052 2004819 4200489 298809 0 0 0 7012608 5774438 0 451983 0 0 5209493 0 0 0 0 5554507 4546661 8516476 0 0 5435445 0 0 0 2996912 3853193 6819165 3671124 0 671010 0 1342644 0 1047072 1701867 736868 0 619946 831513 0 0 0 745114 998288 0 1790751 0 0 602177 0 1428059 0 1309055 618983 435467 897618 0 0 0 621017 0 0 726290 298042 867620 922996 1277541 +AAGPAAFVTR MGYG000000133_01810 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 9.98 1.0 metY 1.0 - 1.0 2.5.1.49 1.0 ko:K01740 1.0 ko00270,ko01100,map00270,map01100 1.0 - 1.0 R01287,R04859 1.0 RC00020,RC02821,RC02848 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding_2,Cys_Met_Meta_PP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01810 1.0 O-acetylhomoserine aminocarboxypropyltransferase. OAH sulfhydrylase. Also reacts with other thiols and H2S, producing homocysteine or thioethers.-!-The name methionine synthase is more commonly applied to EC 2.1.1.13.-!-The enzyme from Saccharomyces cerevisiae also catalyzes the reaction of EC 2.5.1.47, but more slowly.-!-Formerly EC 4.2.99.10. methanethiol + O-acetyl-L-homoserine = acetate + H(+) + L-methionine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways 1.0 K01740:metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49] 1.0 none 1.0 0 768533 0 0 0 1352938 0 0 0 0 0 783780 0 0 0 0 0 0 0 0 397482 1180528 0 250819 0 0 0 0 0 0 401182 392005 0 0 0 0 0 882509 0 0 0 0 0 0 0 0 0 0 0 168188 0 0 0 0 0 0 0 0 251894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168535 0 0 0 0 0 665266 0 0 0 0 0 0 0 0 285723 505136 0 610593 0 0 0 0 0 0 0 390112 678364 0 0 0 0 0 0 3136612 2837590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331475 0 371369 0 0 0 0 0 0 0 0 1006030 0 0 0 0 0 0 14340032 11031785 0 0 6842466 0 0 0 0 0 9472391 0 0 0 0 0 0 0 0 10953280 12166736 0 7207268 0 0 0 0 0 0 9226452 6539338 13732583 0 0 0 0 7830548 +AAGPAAGA(Ala->Gln)AAAEEK MGYG000004797_04276;MGYG000001345_04691;MGYG000001337_03901;MGYG000002478_00807;MGYG000000236_01800 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_04276 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2604254 0 0 0 0 0 0 0 0 0 0 0 0 +AAGPAAGAAAAEEK MGYG000004797_04276;MGYG000001345_04691;MGYG000001337_03901;MGYG000002478_00807;MGYG000000236_01800 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_04276 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 9848163 7377080 4488914 0 8967043 0 10224312 5281392 0 6012387 0 0 0 8584785 6611572 18677597 7745287 0 0 7614749 0 6941364 12467599 0 6380124 9178943 11226629 0 8211916 0 0 0 0 5830533 0 9340575 7746459 5691951 9822225 6300020 10393019 9578382 12989594 8793647 6705831 9747477 0 9143065 0 8410689 0 11496430 8598836 17334347 8176552 0 10976469 9426399 8130149 8101531 10094460 0 8739755 9662427 9479984 8096801 8214289 9682066 6836733 8906733 9180638 6592074 0 8931518 0 7900052 3014450 2771700 6498577 3403147 8560910 5568791 4885225 2162068 5652534 3565965 5866100 3558388 8465158 4071975 3760924 7301977 3258546 9548847 2947312 3412623 2910159 0 7897361 4516285 3452298 3825204 3209091 5625665 3929588 2911362 5044653 3200350 2865591 1610592 2865610 5757661 4409078 5353700 0 4356408 4181661 3893043 5056657 4354803 4959347 4099916 4571465 5754349 8535909 4830968 7402049 4477018 4099786 7220787 4469745 5153146 4226250 4571514 3468223 4049091 3043786 4898343 5117662 5631408 5226218 3599505 0 3916754 4372828 4524091 4483425 2819334 5199992 6240674 5124708 3819544 6255970 3214599 4788526 4627975 0 7964030 3886316 8384632 8611449 3860676 6598007 5162470 16794757 5326796 5485519 14303044 5599589 20082997 7595990 9623855 0 0 17952388 8848084 8922241 0 5980229 13098897 6350339 3751579 5259256 3411994 4432373 8258598 10898350 0 0 5909674 +AAGPAAGAAAAEEKTSFDVVLK MGYG000004797_04276;MGYG000001345_04691;MGYG000002478_00807 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22Y4T@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_04276 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 1584254 0 0 0 3496988 1928574 0 0 0 1459882 3875730 2141839 3590874 1555590 1275042 2985238 2011764 1105619 1475029 0 1621616 1357144 1469476 0 1391009 2318343 1807716 0 1803751 0 3580884 0 1942449 0 2129381 1457752 1819927 1825681 371948 315396 375983 486902 1261167 494090 256779 0 222377 465448 0 246036 1417819 395199 713468 1345060 552053 0 337415 315350 456861 735173 0 374365 224618 341130 422692 0 383723 0 391138 734289 328049 0 449221 449686 303644 497068 653423 1456464 1637647 970624 2178431 1645906 1187239 0 1292055 938130 1651631 1760257 1806576 837077 1009905 1830188 0 1078309 1890874 844466 882842 735462 811557 1318936 937437 1668028 0 1050548 938972 0 1185805 984398 0 0 1144555 1234678 1029710 1478460 0 456520 654594 458939 487519 0 530875 0 435546 445583 862344 735948 595935 449319 474809 611264 578828 470925 334214 360880 690692 463708 352367 360902 554432 815122 427441 439189 301068 0 288507 479202 448122 0 640300 563130 634541 339705 1291802 951595 971223 969212 0 1245916 655052 0 910277 975606 1313720 804677 4311375 1177945 1234021 1861743 534969 0 0 957686 178971 0 490935 2030950 0 0 582273 460563 2441147 0 1612805 933065 741384 0 0 0 1384486 1652474 +AAGPAAGAAAEEEKSAFDVVLK MGYG000002556_01325 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-279|s__CAG-279 sp000437795|m__MGYG000002556 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002556_01325 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436669 0 0 0 0 325642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 961962 0 0 0 0 921796 0 0 0 0 772593 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165850 0 0 0 0 0 0 0 0 0 0 +AAGPAAGAAAV(Val->Ala)EEK MGYG000000098_02010;MGYG000000054_03940;MGYG000003312_01245;MGYG000000196_03981 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000098_02010 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGPAAGAAAVEEK MGYG000000098_02010;MGYG000000054_03940;MGYG000003312_01245;MGYG000000196_03981 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000098_02010 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 6511706 5803885 3889985 6035743 4681185 4872985 0 4432853 6051459 0 2932378 0 3685251 5224957 5545346 5411418 5371414 1033810 4292709 5215787 6102107 3997915 1857311 5439714 4315511 6567749 5298875 1305407 4748504 0 5396392 6629416 4390640 6255309 5231200 6304808 0 3930348 3437822 2093033 3743163 3605512 3216151 2788964 2916852 3481129 3601924 3678554 3011491 2959529 2665179 3794908 3151006 2574484 2829666 0 0 2882477 2832518 2989338 412748 2425586 2825414 3187080 2937096 0 3560324 3018888 2797144 3916248 3311064 3532436 2174894 3387888 3807201 3224180 0 0 2327371 2141548 2998404 2152763 2997300 2473622 0 1495481 0 1671893 1531339 2412156 2233547 1883192 2005404 911211 0 2076841 2339070 1398608 657698 1931772 2180512 2374841 2549703 322122 2315565 1668409 2154202 1243348 1299214 0 1611204 3651962 0 0 1630592 1327689 0 0 1320465 1572819 0 2072924 2011171 1570086 1430992 0 1752631 0 1545110 1964031 1710290 935063 1612391 1536340 1596011 1724909 504880 1426450 1979259 2547875 1850420 954777 1043548 1247265 775859 1542397 1719748 2633862 1620654 1908713 1963309 1139871 2178769 1044541 986381 1611303 1620349 0 1292824 2419399 2586658 1816322 1307521 896408 1758137 1019187 1945057 1370710 1452151 427797 1684353 2297209 1138826 1177497 348005 1619285 1424790 2382910 2008631 0 1029412 1909966 856204 1616195 983947 2963313 1870529 2067732 2228262 1625735 +AAGPAAGAGEAAAEK MGYG000004517_00743 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__UBA5884|s__|m__MGYG000004517 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3WJAG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004517_00743 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGPAAGGAAAAEEK MGYG000002080_00533;MGYG000000243_01981;MGYG000002291_02265;MGYG000001056_00099;MGYG000000272_00853;MGYG000003697_01479;MGYG000002293_00514;MGYG000002455_03891;MGYG000002603_01776 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002080_00533 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 8339751 8305973 17124583 7836371 10724049 7097901 10178412 7269974 7793522 5424743 9830072 8884817 11880778 7056820 6868464 12247898 7428509 6322499 6499310 6646826 6928918 7065309 6899151 10137374 0 6423961 7874547 6304508 7201200 7370752 14715387 6464910 18732511 9644746 7054571 10173896 7601945 18188753 7142641 4166012 0 7415696 6179798 0 6502660 0 7746737 7931363 0 9770356 6894695 8485158 6730947 8257012 6632626 3302463 0 6848784 8046510 5936132 5405917 4620594 7854518 0 7599178 4789035 4821181 7388666 3904946 6725571 6241541 5158869 0 6309591 8118477 6716896 5300421 4153639 6741987 6449184 0 0 8787166 4393576 8644959 5279516 15337761 6907439 8418664 7754272 5652181 8499357 5311087 0 4862464 5951861 5885543 5413921 9472268 6346488 5565493 6497865 5170601 8337855 6942271 5691492 7650501 3825765 4119427 2625612 6416786 10036946 0 7155617 10754593 11162963 34148882 7716768 21954283 25870176 10062793 13114122 12399617 11280141 38462212 15329959 25311819 8336017 10234113 21954358 12376841 35790544 8633671 8843935 7356181 44811595 0 33615893 13381070 14022540 11903542 21680984 12185932 7322519 13794625 14908966 25267879 12726283 10396513 13929539 13053688 0 1960821 1275283 1766524 1418068 2455978 1830222 1967167 3273571 2373522 1501587 8841065 2048388 2810107 2153279 1751458 2118856 1548601 6501969 2644168 0 1710281 1647804 6205578 2222244 3248699 0 2068613 6293913 1091983 0 1957130 0 0 3377654 3662191 2276716 2481652 0 +AAGPAAGGAAAAEEKTSFDVVLK MGYG000000243_01981 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01981 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 328550 0 6842524 1280759 0 1597583 1311486 1613783 1522217 0 0 1967325 0 1474198 1652171 1514962 1684244 945974 349076 0 1257847 1362977 1141663 2070960 1215249 1579327 1400249 1304905 1419075 1659386 4929559 2420288 0 1429738 1547881 1185138 1521940 5024079 259893 224740 323454 245106 500681 249975 400473 363194 233837 0 339597 410828 437791 287704 595345 397720 410391 0 271432 0 266147 441962 0 183667 329391 351661 380732 0 266323 261075 231618 372043 248721 327280 423254 318556 266345 309017 714727 881540 950091 1129564 1994033 1313391 1027092 837438 877227 0 2466718 1137085 1697724 1013534 715139 1450380 1109977 948031 817291 0 753256 561098 799379 1228918 765823 1051673 909279 814428 1004961 774654 1339240 814800 675803 534419 1017394 1109869 908921 1139910 421392 253955 455260 441116 400446 342041 382075 541223 417225 0 599122 448673 585914 409153 511658 279143 473740 212956 484700 0 612999 289759 0 351344 419662 574525 424541 0 259942 331373 298661 583037 315750 707666 790524 537206 348366 252688 200436 0 0 253818 335527 307904 0 0 261449 0 1029890 0 443244 0 275008 0 0 0 0 0 0 159490 0 245032 0 202767 0 0 332334 193919 281597 118969 0 244104 337036 0 261774 237349 +AAGPASYGMTDTLGR MGYG000000142_02731;MGYG000000215_01600;MGYG000000127_05084;MGYG000001496_01287;MGYG000004762_01356;MGYG000004733_02764;MGYG000000212_00326 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.8571428571428571 186801|Clostridia 0.8571428571428571 S 1.0 Psort location Cytoplasmic, score 8.87 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_02731 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 785384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 622549 0 0 0 0 0 0 0 0 0 0 0 0 0 647107 779306 0 0 0 815439 0 0 621019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362404 0 0 0 0 0 0 0 0 0 0 0 0 0 719127 427302 0 0 0 437284 0 0 1570239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1348771 0 0 0 0 0 0 0 0 0 0 0 0 0 1574303 1686778 0 0 0 1554746 0 0 1251890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521672 0 0 0 0 0 0 0 0 0 0 0 0 0 670757 835269 0 0 0 785008 0 0 743651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 659427 0 0 0 0 0 0 0 0 0 0 0 0 0 1020633 808283 0 0 0 942702 +AAGPASYGMTDTMGR MGYG000000118_02684;MGYG000000028_01055;MGYG000004482_01421;MGYG000003589_01350;MGYG000004604_01207;MGYG000000179_04738;MGYG000001415_02505;MGYG000002528_00119;MGYG000000515_00648;MGYG000000269_00015;MGYG000000205_02543;MGYG000004594_01436;MGYG000002218_00562;MGYG000000262_01832;MGYG000004517_01958;MGYG000001400_01185;MGYG000002517_01686;MGYG000000187_00466;MGYG000004822_01055;MGYG000002492_01963;MGYG000000198_05683;MGYG000001697_00682;MGYG000002438_03055;MGYG000004561_02010;MGYG000004464_00921;MGYG000000245_00061;MGYG000000251_02115;MGYG000001881_00612;MGYG000000312_02568;MGYG000000045_01847;MGYG000002213_00389;MGYG000000233_02118;MGYG000001599_00424;MGYG000004797_02907;MGYG000001423_03082;MGYG000000249_02372;MGYG000001346_01121;MGYG000002148_02635;MGYG000002880_00963;MGYG000002478_02896;MGYG000000223_01510;MGYG000004276_01664 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3WGV8@541000|Ruminococcaceae 0.14285714285714285 186801|Clostridia 0.5476190476190477 S 0.9285714285714286 Psort location Cytoplasmic, score 0.30952380952380953 - 0.8095238095238095 - 1.0 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 1.0 - 1.0 - 1.0 GGGtGRT 0.9285714285714286 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000118_02684 0.023809523809523808 - - - - 0.9285714285714286 0.9285714285714286 0.9285714285714286 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1844059 1298443 2511759 1526577 0 1580807 2256783 1600831 2220101 1554162 1407507 1557086 1952633 1458269 1802682 1407155 1080500 0 1847872 2283628 1509974 1395588 0 1101096 1810980 2012054 1593178 0 1841336 2265160 1162304 0 2010191 2364446 1450139 2509650 2346386 1747826 0 0 0 370694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 659950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGPLFESAK MGYG000002720_01678 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,36DTA@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 PFAM Extracellular ligand-binding receptor 1.0 - 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01678 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 1.0 K01999:livK; branched-chain amino acid transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 2821560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGPVEAAEEKTEFDVILK MGYG000002494_02480;MGYG000002506_03692;MGYG000002323_03990;MGYG000002534_04619;MGYG000002477_00982 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,1S5V7@1236|Gammaproteobacteria,3XPRN@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0046983,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02480 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 720285 497899 706568 571292 379696 813531 896103 496670 838897 701818 348968 487261 185282 674673 757625 97090 577338 0 492281 373709 445134 728220 0 1327026 663716 719879 734014 0 909370 837738 962046 645172 632250 592762 569294 625844 634741 583174 1062921 1028563 1318536 1151039 1385651 2278603 1291085 1073566 1138933 1363625 774646 1524404 579919 1195952 1150865 1273853 2042407 0 1561783 1127800 1121984 3215104 0 1122624 1277614 1021546 1175210 0 913273 1132126 416865 1321032 909001 865541 836516 1016212 802566 768068 860569 910764 1040957 1039832 1474803 2530710 1220283 1110015 964411 958602 1026404 1224254 841543 1083403 797286 857285 2297096 0 900572 1152419 1534433 1374327 0 2309589 707753 483281 1075083 0 1046097 1062688 1771156 1001067 1237739 965405 897426 1224120 658480 1214821 413255 325369 406060 280638 229725 271761 409262 361539 275268 260120 172992 270023 0 211285 256242 207234 323231 0 273035 246453 488507 209031 0 259338 305071 391624 239728 0 185859 338678 185449 305574 300007 877247 642869 489896 316614 314515 0 371167 171144 105340 269850 202106 352998 0 0 211203 379850 351894 173048 212189 0 263553 396369 0 270337 0 0 832744 0 511091 0 0 202494 0 443418 0 466109 432718 282757 259725 589607 240076 251643 0 +AAGQAWIDSVNDAEASK MGYG000003274_00602;MGYG000003266_01692 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,2I995@201174|Actinobacteria,4CUGM@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000003274_00602 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 271679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 873128 0 0 1454039 0 0 0 0 0 0 0 0 0 0 0 0 0 812553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGQDDILAFR MGYG000003166_00709;MGYG000001300_00361 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3WHAH@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 M18 family aminopeptidase 1.0 apeA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CoaE,Peptidase_M18 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_00709 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 306465 0 0 503792 352805 0 0 0 0 0 0 0 0 0 811719 730046 728240 519552 0 600003 0 360628 0 0 0 698424 0 0 0 0 402722 0 0 0 0 165253 0 0 472967 0 0 688817 1278593 0 0 0 0 662542 0 0 856066 0 746509 522237 997339 834559 0 365162 358172 541376 1112365 0 0 0 0 0 638737 0 697075 0 0 0 0 440410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 562459 0 0 919089 1092385 0 0 0 0 579612 0 0 529297 0 323765 0 0 962474 0 0 0 533518 590221 0 0 474085 0 0 1391719 0 0 0 0 0 0 0 0 0 324550 0 0 418692 0 0 0 0 0 432456 0 0 0 0 0 1404017 0 0 0 0 1812312 0 266257 0 0 1853028 0 0 0 0 0 0 0 0 0 673307 +AAGQENIFGNQVK MGYG000002517_00959;MGYG000000154_00174 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002517_00959 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 950712 0 0 0 0 0 0 0 0 0 0 0 0 0 1060091 0 1209184 0 0 0 0 0 0 0 0 499018 1261186 0 0 0 0 0 0 0 0 0 860023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGQEWLDTFSVGATN(Deamidated)GTATDK MGYG000000133_02129 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000133_02129 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1018249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGQEWLDTFSVGATNGTATDK MGYG000000133_02129 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3WH0Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000133_02129 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2298974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGQIDC(Carbamidomethyl)SR MGYG000002506_04505;MGYG000002323_00920 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG3477@1|root,COG3477@2|Bacteria,1MV9E@1224|Proteobacteria,1RYHM@1236|Gammaproteobacteria,3XQGU@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 response to acidic pH 1.0 yagU 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016020,GO:0044464,GO:0050896,GO:0071944 1.0 - 1.0 ko:K08996 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF1440 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04505 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K08996:yagU; putative membrane protein 1.0 none 1.0 0 0 0 0 0 880099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1328411 0 1527733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1210054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1098614 0 1259439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2612791 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2119133 0 3096910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1196450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 806985 0 1117288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGSATISAPMPGK MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_00268 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 360509 0 0 0 0 0 0 0 0 275790 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219601 321780 278389 0 0 0 0 0 1198823 990639 1063347 590494 876619 515698 724312 1697315 934454 884719 496362 797178 389700 721463 854683 495210 1120060 0 835953 1027596 1079437 518755 0 488809 883552 992948 1019195 0 449649 822809 291650 1195230 1342878 931189 1484394 1288379 870441 624528 801460 1246785 1318459 786506 1378894 1737812 1292577 1424722 1391730 889442 1780635 1385879 1133155 1249369 728323 1519362 965593 0 755728 971735 1102042 1048215 0 1262446 967393 766795 749035 0 1093779 957776 1965455 1522913 1198440 1032275 923722 1249512 1215972 1582100 1828648 2363875 3797352 1547653 2285961 2454580 1463956 2499115 1417909 2022791 2610517 2303550 2042227 1729002 1797187 1847530 1420153 0 1683550 1458344 1969479 3541896 0 3100025 1717146 1815033 1492446 0 1805220 1865840 2442767 2617159 4178249 1818031 2742083 2081723 1595783 3156496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGSDLEYEVGTM(Oxidation)IEIPR MGYG000000142_02834;MGYG000001315_01921 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.5 186801|Clostridia 1.0 G 1.0 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 0.5 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000142_02834 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGSDLQYEVGTM(Oxidation)IEIPR MGYG000000184_00575;MGYG000000140_01464;MGYG000000171_00241;MGYG000004785_01840;MGYG000001338_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.8 186801|Clostridia 1.0 G 1.0 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 0.8 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000184_00575 0.2 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 443540 0 0 574774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328432 601172 0 0 0 0 0 0 0 532772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858484 0 0 0 0 0 0 0 0 1056796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 731211 0 0 0 0 0 0 0 714140 0 0 476234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736287 438429 0 0 0 0 0 0 0 573681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525470 0 0 0 0 0 0 0 +AAGSDLQYEVGTMIEIPR MGYG000000184_00575;MGYG000000140_01464;MGYG000000171_00241;MGYG000004785_01840;MGYG000001338_02151 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.8 186801|Clostridia 1.0 G 1.0 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 0.8 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000184_00575 0.2 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGSDMKYEVGTMIEIPR MGYG000000262_01988;MGYG000002707_01357 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25VEG@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000262_01988 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 113421 0 0 71393 168111 0 0 0 0 0 0 0 289795 0 0 0 0 0 0 313729 160627 126757 0 0 0 0 92693 0 91350 255006 0 0 0 0 0 0 0 0 0 0 336683 0 116063 0 0 289730 0 0 0 0 0 200725 0 0 0 0 0 0 0 208717 0 0 253136 0 568062 0 280083 781616 0 0 0 541421 0 586204 0 0 580001 0 595419 540462 670092 0 0 525072 0 0 0 0 545826 532089 681082 0 0 0 0 850902 455308 612799 721098 0 343102 126721 0 0 0 92487 0 0 0 0 0 0 0 0 0 0 0 243216 0 0 0 194375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231672 0 0 0 0 119392 +AAGSDNVMLISDR MGYG000004736_00489;MGYG000002448_00117;MGYG000001225_00663 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Evtepia 1.0 COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WGYX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 - 1.0 - 1.0 1.1.1.1 1.0 ko:K13954 1.0 ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00623,R00754,R04880,R05233,R05234,R06917,R06927 1.0 RC00050,RC00088,RC00099,RC00116,RC00649 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004736_00489 0.3333333333333333 alcohol dehydrogenase. aldehyde reductase. Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K13954:yiaY; alcohol dehydrogenase [EC:1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 345939 0 0 0 0 0 0 0 1604755 0 1068317 0 0 1025816 0 0 0 0 1417459 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1428966 0 0 0 0 0 0 0 687606 0 1964001 0 0 804866 0 0 0 0 1089669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1782300 0 0 0 0 0 0 0 1202989 0 1404112 0 0 1160461 0 0 0 0 1812109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2390933 0 0 0 0 0 0 0 816357 0 1301349 0 0 1505689 0 0 0 0 1191680 0 0 0 0 0 0 0 0 0 0 +AAGSTVTGGISQLTAGGR MGYG000000301_01629 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900541985|m__MGYG000000301 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia,3XYNF@572511|Blautia 1.0 186801|Clostridia 1.0 S 1.0 Psort location CytoplasmicMembrane, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ABC2_membrane_3,DUF3533 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_01629 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01421:yhgE; putative membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 760362 0 0 0 0 0 0 929288 0 0 0 0 0 0 0 0 0 0 1012991 0 0 0 0 0 0 0 0 0 0 0 1507580 0 0 0 0 480784 +AAGTDLAGIEK MGYG000000243_00604 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG2025@1|root,COG2025@2|Bacteria,4NFSE@976|Bacteroidetes,2FMEK@200643|Bacteroidia,4AKN9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 8.96 1.0 etfA 1.0 - 1.0 - 1.0 ko:K03522 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00604 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055278 0 0 0 0 0 0 1505272 0 0 303781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGTDLSHVVK MGYG000003697_02933;MGYG000002960_01238;MGYG000002293_00704 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0251@1|root,COG0251@2|Bacteria,4NQ8M@976|Bacteroidetes,2FT8J@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 endoribonuclease L-PSP 1.0 ridA 1.0 - 1.0 3.5.99.10 1.0 ko:K09022 1.0 - 1.0 - 1.0 R11098,R11099 1.0 RC03275,RC03354 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ribonuc_L-PSP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_02933 0.3333333333333333 2-iminobutanoate/2-iminopropanoate deaminase. enamine/imine deaminase. This enzyme, which has been found in all species and tissues examined, catalyzes the hydrolytic deamination of imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases, such as EC 4.3.1.19 and EC 4.3.1.17.-!-The reactions, which can occur spontaneously, are accelerated to minimize the cellular damage that could be caused by these reactive intermediates. (1) 2-iminobutanoate + H2O = 2-oxobutanoate + NH4(+). (2) 2-iminopropanoate + H2O = NH4(+) + pyruvate. 1.0 1.0 1.0 1.0 - 1.0 K09022:ridA, tdcF, RIDA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 62477 0 0 0 0 95794 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2685601 0 0 0 0 2771183 0 0 0 0 2073089 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGTFTTNIVK MGYG000000133_01203 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3XZ0G@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate 1.0 argJ 1.0 - 1.0 2.3.1.1,2.3.1.35 1.0 ko:K00620 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028 1.0 R00259,R02282 1.0 RC00004,RC00064 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ArgJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01203 1.0 amino-acid N-acetyltransferase. | glutamate N-acetyltransferase. N-acetylglutamate synthase. | ornithine transacetylase. Also acts with L-aspartate and, more slowly, with some other amino acids. | Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity. acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate. | L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L- glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00620:argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] 1.0 none 1.0 0 0 0 305626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 839263 1606329 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1154596 0 0 0 0 0 +AAGTGMIAGGPVR MGYG000002545_01123 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_G|m__MGYG000002545 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3WICZ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002545_01123 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2135975 0 0 0 0 3100330 0 0 0 0 2722953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1999236 0 0 0 0 1464105 0 0 0 0 1528542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 986254 0 0 0 0 649686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGTKELGESM(Oxidation)GNLYIAQGQYER MGYG000000196_01844;MGYG000000013_02380;MGYG000000098_00424;MGYG000001345_04496;MGYG000002549_03156;MGYG000003351_03471 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_01844 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGTKELGESMGN(Deamidated)LYIAQGQYER MGYG000000196_01844;MGYG000000013_02380;MGYG000000098_00424;MGYG000001345_04496;MGYG000002549_03156;MGYG000003351_03471 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_01844 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 709846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485545 0 0 0 0 462240 0 0 254369 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139596 0 0 0 0 280940 0 0 373904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGTKELGESMGNLYIAQGQYER MGYG000000196_01844;MGYG000000013_02380;MGYG000000098_00424;MGYG000001345_04496;MGYG000002549_03156;MGYG000003351_03471 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_01844 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 1317795 0 882480 0 0 1240407 0 0 0 0 0 674526 0 0 0 0 582183 0 0 0 0 0 0 0 0 0 0 0 0 0 796145 0 0 0 0 910904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378579 0 404624 0 0 315085 0 0 0 0 0 207285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222931 0 0 0 0 0 0 0 208258 0 269440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352515 0 0 0 0 419438 0 0 0 0 325069 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGTLLK MGYG000002478_02998 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,4ANQH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02998 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1239292 0 0 0 0 0 0 1019425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1916077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1232760 0 0 0 0 0 0 778099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618023 0 0 0 0 0 0 431062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2728455 0 0 0 0 0 0 1492727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGTSQMTGK MGYG000002517_02558 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1942@1|root,COG1942@2|Bacteria,1VBFY@1239|Firmicutes,24MXU@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 macrophage migration inhibitory factor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MIF,Tautomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02558 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032803 0 0 0 0 0 0 898484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 681014 1006494 0 0 0 0 0 0 0 0 0 0 1147742 0 2620126 0 0 0 0 0 0 1737685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1704067 0 0 0 0 0 0 0 0 0 0 0 2495313 0 +AAGTTLDIVR MGYG000003891_01771 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4H35I@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_01771 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1222437 0 0 0 0 1259070 0 0 0 0 1114951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289158 0 0 0 0 452622 0 0 0 0 416702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244025 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGV(Val->Pro)ESVVFDR MGYG000002834_00456;MGYG000003697_01452;MGYG000001770_00593 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002834_00456 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 346361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVAVGAHPGYPDLMGFGR MGYG000001356_00420 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter sp000177015|m__MGYG000001356 1.0 COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,249GD@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 Belongs to the UPF0271 (lamB) family 1.0 - 1.0 - 1.0 - 1.0 ko:K07160 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 LamB_YcsF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001356_00420 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07160:pxpA; 5-oxoprolinase (ATP-hydrolysing) subunit A [EC:3.5.2.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133556 0 0 0 0 0 0 0 0 0 404798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 632471 0 0 0 0 445934 0 0 0 0 344101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185471 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 745324 0 0 0 0 222910 0 0 0 0 551280 0 0 0 0 0 0 0 0 0 0 +AAGVDATVQTEALK MGYG000000249_00064 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 1.0 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_00064 1.0 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Glyoxylate and dicarboxylate metabolism|Nitrogen metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Biosynthesis of amino acids|Two-component system|Necroptosis|Glutamatergic synapse|GABAergic synapse 1.0 K01915:glnA, GLUL; glutamine synthetase [EC:6.3.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2257248 0 0 0 0 1513062 0 0 0 0 1937550 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 919284 0 0 0 0 544466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 838116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603080 0 0 0 0 0 0 0 0 0 0 +AAGVDITSSERPGTVGSIR MGYG000002478_00199 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00199 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 478478 0 0 0 0 0 0 0 0 0 0 0 0 1125538 0 0 0 0 1021155 0 0 0 0 799394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670768 0 0 0 0 0 0 0 0 0 0 0 0 2848737 0 0 0 0 2586186 0 0 0 0 2494168 0 0 0 0 0 0 0 0 0 0 +AAGVESVVFDR MGYG000002834_00456;MGYG000003697_01452;MGYG000001770_00593 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002834_00456 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 470389 0 0 0 0 0 1335634 0 0 0 0 273122 0 0 0 0 0 310472 0 0 0 0 0 1207842 0 0 0 0 0 0 0 0 724198 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 751937 0 6656409 0 2541547 3959721 0 0 1073816 0 5869460 2143664 3433889 0 0 3403670 1045747 8650973 782609 0 1373741 6611776 11009421 0 0 1255818 0 4746795 1493551 0 2471950 2991294 4046652 1803574 0 0 1043764 4711868 799129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128517 0 0 0 0 0 0 0 0 0 0 598503 0 0 0 0 0 0 0 0 0 +AAGVESVVFDRN MGYG000003697_01452 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01452 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 415276 0 0 0 0 663756 0 0 0 0 592615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1933072 0 0 0 0 1807864 0 0 0 0 2748156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVESVVFDRN(Deamidated)GYLYHGR MGYG000003697_01452 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01452 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4290622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177634 0 183536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 630489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 622820 0 278282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 450796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVET(Thr->Ser)VVFDR MGYG000003493_00797 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp002299275|m__MGYG000003493 1.0 COG0256@1|root,COG0256@2|Bacteria,4NQAS@976|Bacteroidetes,2FSHX@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance 1.0 rplR 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 1.0 - 1.0 ko:K02881 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L18p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003493_00797 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02881:RP-L18, MRPL18, rplR; large subunit ribosomal protein L18 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3757866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5125417 1374252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVEVEELTK MGYG000002445_02594 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp003024715|m__MGYG000002445 1.0 COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,21YYA@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein-like domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10540 1.0 ko02010,ko02030,map02010,map02030 1.0 M00214 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.3 1.0 - 1.0 - 1.0 Peripla_BP_4,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002445_02594 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Bacterial chemotaxis 1.0 K10540:mglB; methyl-galactoside transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 1101568 1363573 0 1944711 0 1958685 1755451 0 0 0 1413329 1031901 0 0 0 0 0 1729600 0 1940182 1580887 0 1577939 0 0 0 0 0 0 2679565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 369367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524834 0 0 0 0 0 0 0 0 1866183 1939868 0 1530697 0 1998456 1436437 0 0 0 1894669 1447133 0 0 0 0 0 1745247 0 2127111 1568757 0 1471588 0 0 0 0 0 0 2140017 0 0 0 0 0 0 0 0 1017145 764464 0 670456 0 711421 1334636 0 0 0 585620 741341 0 0 0 0 0 891419 0 1116542 529060 0 853182 0 0 0 0 0 0 602422 0 0 0 0 0 0 0 0 0 0 0 495770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVFVQAGGGPLGETTIR MGYG000002438_00957 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22XE6@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 MGYG000002438_00957 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463784 0 0 0 738060 541887 0 0 0 651373 0 1650924 0 0 0 0 0 125490 541276 0 1440505 542112 0 383293 0 667100 593185 0 0 1300795 401877 1216204 0 0 0 0 622462 0 0 0 0 0 426800 275984 0 0 0 332714 0 811155 0 0 0 0 0 0 0 0 812839 0 195270 314006 0 0 0 218051 0 564969 314240 389171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384818 0 0 0 1325350 426956 0 0 0 348210 0 2002242 0 0 0 0 0 832468 403666 0 2433392 225973 559712 482632 0 366727 346747 630889 0 3098091 468217 1507872 0 0 0 0 657201 0 +AAGVLFAPERGEDTR MGYG000000243_00236 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG4980@1|root,COG4980@2|Bacteria,4NXMW@976|Bacteroidetes,2FUB7@200643|Bacteroidia,4ARS7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG35214 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 YtxH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00236 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 3162532 3813951 8761248 3367860 4214632 3479614 3367327 0 3056225 3204847 3121458 3944162 4813834 3661340 2807465 4584032 3732543 1583465 3944205 2549600 0 2884637 2459117 4823254 0 3934730 3305193 2212187 3126969 3965998 6708232 4880713 6650871 4232265 3508522 3458460 3396726 8761459 574451 437116 737969 248760 1061896 515132 544156 0 824757 1095680 766947 632754 1895488 727281 700890 796033 683691 148893 780359 615143 0 692011 265540 361146 0 571757 571865 183374 629828 629249 339627 755793 769838 651689 648549 668007 739572 710411 1719774 1542261 1993341 1679231 2858916 2701978 1550652 0 1918593 1652238 1965265 1546634 2883773 1587437 1642411 2514675 2754777 1702984 1400606 2030331 0 1103707 1439576 2000366 0 1750280 1669299 1291229 1192980 1307124 2418289 1327937 1367163 541569 1997950 2216200 1669078 1662592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVLFGTAGIK MGYG000002528_03117;MGYG000000146_03297;MGYG000000187_02198;MGYG000000217_00093;MGYG000000251_02450 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,27VWC@189330|Dorea 0.6 186801|Clostridia 1.0 S 1.0 H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_03117 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1205362 0 0 0 0 963037 0 0 0 0 1003579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVLISYDPNYRPSLWK MGYG000002492_01273;MGYG000000268_02012 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3WGC8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.7.1.4 1.0 ko:K00847 1.0 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 1.0 - 1.0 R00760,R00867,R03920 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01273 0.5 fructokinase. D-fructokinase. - ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K00847:E2.7.1.4, scrK; fructokinase [EC:2.7.1.4] 1.0 none 1.0 0 0 948007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1049351 0 0 0 0 0 0 822016 0 0 1158921 0 2835755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3797253 0 1002504 0 0 0 0 1539020 0 0 1019721 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742877 0 2781604 0 0 0 0 1700626 0 0 0 0 166229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298360 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1910003 0 0 0 0 0 0 694374 +AAGVNIFSNSSQPGAYGSR MGYG000002438_03984 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2G0K7@200643|Bacteroidia,231FG@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03984 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 449788 0 436654 0 123398 568958 0 0 0 396708 448019 0 266216 0 0 0 784428 333620 0 1045688 287471 681822 0 287808 196891 321585 0 0 0 506282 245988 388978 345033 0 0 0 0 617338 456100 365891 180779 0 318807 981812 0 0 0 441888 383078 1635723 177314 0 0 419241 539256 0 0 193975 1255042 611583 0 0 199560 292606 0 0 0 1023236 532734 749234 389153 0 0 0 350047 337495 175726 183118 0 0 213844 0 0 0 0 0 0 613703 316512 0 0 0 0 0 0 0 536766 0 301496 0 0 322619 0 0 0 434153 285261 0 0 0 0 0 0 0 0 292037 445540 0 286299 546019 0 266473 0 298135 0 414389 0 0 0 0 396230 516035 0 0 862241 691166 428513 0 0 0 0 314395 0 0 266347 0 0 0 0 0 0 0 556612 685688 428749 0 1353529 728345 0 667637 0 636263 772947 2007463 1000983 0 0 1191086 615481 783371 0 738083 2284129 586291 552061 587230 650193 721978 0 600458 0 2052894 641090 1757989 389333 0 0 0 736879 806017 +AAGVPC(Carbamidomethyl)IADGGIHYSGDIAK MGYG000003683_00984;MGYG000000756_00094 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2GITZ@201174|Actinobacteria,4CZ2S@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006183,GO:0006195,GO:0006204,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009125,GO:0009126,GO:0009127,GO:0009128,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009154,GO:0009156,GO:0009158,GO:0009161,GO:0009163,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009169,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009261,GO:0009987,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046037,GO:0046039,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:0097292,GO:0097293,GO:1901068,GO:1901070,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901659 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00984 0.5 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 383195 0 0 0 0 579810 0 0 0 320718 0 0 0 0 0 546031 254226 0 152295 0 0 0 0 0 0 0 0 0 0 0 0 925597 0 0 0 0 0 0 1356765 0 0 0 0 2760964 0 0 0 660293 1115663 1610660 0 0 0 1754576 917353 0 938164 0 0 0 0 0 0 0 0 0 0 0 0 367345 0 0 0 0 0 0 521371 0 0 0 0 409725 0 0 0 573486 0 0 0 0 0 453249 377761 0 369064 0 0 0 0 0 0 0 0 0 0 0 0 582289 0 0 0 0 0 0 382431 0 0 0 0 298280 0 0 0 975277 0 582127 0 0 0 732432 461640 0 523678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVPLIR MGYG000004885_00927 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotellamassilia|s__|m__MGYG000004885 1.0 COG0795@1|root,COG0795@2|Bacteria,4NE8B@976|Bacteroidetes,2FP6P@200643|Bacteroidia,1WD05@1283313|Alloprevotella 1.0 976|Bacteroidetes 1.0 S 1.0 Predicted permease YjgP/YjgQ family 1.0 - 1.0 - 1.0 - 1.0 ko:K07091 1.0 ko02010,map02010 1.0 M00320 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 1.B.42.1 1.0 - 1.0 - 1.0 YjgP_YjgQ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004885_00927 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K07091:lptF; lipopolysaccharide export system permease protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVPVVVAVNK MGYG000002494_01785 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,3WXXB@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002494_01785 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 928107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1370575 0 977640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVPVVYTGPVDR MGYG000003683_01311;MGYG000001292_02510;MGYG000002469_01931 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4CZ2W@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 M 1.0 UDP-galactopyranose mutase 1.0 glf 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 1.0 5.4.99.9 1.0 ko:K01854 1.0 ko00052,ko00520,map00052,map00520 1.0 - 1.0 R00505,R09009 1.0 RC00317,RC02396 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iNJ661.Rv3809c 1.0 GLF,NAD_binding_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01311 0.3333333333333333 UDP-galactopyranose mutase. - - UDP-alpha-D-galactose = UDP-alpha-D-galactofuranose. 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism 1.0 K01854:glf; UDP-galactopyranose mutase [EC:5.4.99.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1668280 0 0 0 0 876458 0 0 0 0 1157749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424397 0 0 0 0 523069 0 0 0 0 0 0 0 0 0 0 +AAGVQIINSGGPGEAADIR MGYG000002293_00434;MGYG000003697_01963 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FN3Y@200643|Bacteroidia,4AP89@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00434 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4364056 0 0 0 0 7122280 0 0 0 0 2344288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVQILNTSGAPGEGAK MGYG000003681_01919;MGYG000004748_01490 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FN3Y@200643|Bacteroidia,4AP89@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_01919 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2026639 1090645 1782843 2633117 1212567 0 1607653 2447341 2137153 1864532 0 0 0 2356682 2372366 0 1171301 1316387 2969960 2200019 1784138 1912128 2007861 1335360 2066869 2504878 2248740 1523081 1843176 2253150 1202539 1563095 1546048 2023416 2248508 2379276 2362506 1838248 1337699 1679717 2048724 1508462 0 2457559 2222938 1575603 1953823 1775439 0 0 0 1537045 1460148 0 1639861 0 2050484 1265393 0 1435264 5035222 2027075 1419988 1616654 1477545 5113118 1727287 1635126 2242207 1441971 1306841 1599436 1574433 1707421 1531486 1669942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVQILNTSGAPGEGAQ(Gln->Lys) MGYG000000224_01965 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides sp003545565|m__MGYG000000224 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FN3Y@200643|Bacteroidia,4AP89@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000224_01965 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2205014 0 0 0 0 0 0 0 0 1368370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVQVTTPSGVLGSGPQFK MGYG000002438_02058 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG4773@1|root,COG1629@2|Bacteria,COG4773@2|Bacteria,4NDXS@976|Bacteroidetes,2G0KF@200643|Bacteroidia,22XIH@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02058 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742103 0 0 0 0 0 0 0 0 1043744 0 0 0 0 0 0 0 0 755240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVSAAALGLAAC(Carbamidomethyl)GGSSSSTASSAASSTAASSTAAK MGYG000001300_01498 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_01498 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1616270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1926530 0 0 0 0 0 0 0 0 0 0 2033197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1672940 0 +AAGVSAVTTSGAPGSSSSIR MGYG000000781_01055 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900541515|m__MGYG000000781 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4AWF7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 MGYG000000781_01055 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1502166 0 0 0 0 1949948 0 0 0 0 1764356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVSC(Carbamidomethyl)VIAETFAR MGYG000002989_00741;MGYG000001777_01812;MGYG000004414_01361;MGYG000000287_00506;MGYG000000562_02520;MGYG000001814_00377;MGYG000000271_00011;MGYG000004839_01241;MGYG000004879_00262;MGYG000002212_01424;MGYG000002966_02377;MGYG000004271_00401;MGYG000001689_05207;MGYG000000002_02744;MGYG000000154_00764;MGYG000004891_01102;MGYG000004869_03018;MGYG000004317_00793;MGYG000000301_00842;MGYG000000806_02465;MGYG000001637_01147;MGYG000000153_00377;MGYG000000050_00293 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia 0.34782608695652173 186801|Clostridia 1.0 E 1.0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate 1.0 leuD 0.9130434782608695 - 1.0 4.2.1.33,4.2.1.35,4.2.1.85 1.0 ko:K01704,ko:K20453 0.9130434782608695 ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230 0.9130434782608695 M00432,M00535 1.0 R03069,R03896,R03898,R03968,R04001,R10170 0.9130434782608695 RC00843,RC00976,RC00977,RC01041,RC01046,RC03072 0.9130434782608695 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 0.9130434782608695 Aconitase_C 0.9130434782608695 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002989_00741 0.043478260869565216 3-isopropylmalate dehydratase. | (R)-2-methylmalate dehydratase. | dimethylmaleate hydratase. isopropylmalate isomerase. | citraconate hydratase. Forms part of the leucine-biosynthesis pathway.-!-Brings about the interconversion of the two isomers of isopropylmalate. | Inhibited by oxygen.-!-Forms part of the nicotinate-fermentation catabolism pathway in Eubacterium barkeri.-!-Other enzymes involved in this pathway are EC 1.17.5.1, EC 1.3.7.1, EC 3.5.2.18, EC 1.1.1.291, EC 5.4.99.4, EC 5.3.3.6 and EC 4.1.3.32. (2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate. | (3R)-citramalate = 2-methylmaleate + H2O. | (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H2O. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|C5-Branched dibasic acid metabolism|Nicotinate and nicotinamide metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 0.9130434782608695 K01704:leuD, IPMI-S; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]|K20453:dmdB; dimethylmaleate hydratase small subunit [EC:4.2.1.85] 0.9130434782608695 none 1.0 0 0 649702 0 0 0 0 0 0 0 0 0 0 564116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 695359 0 0 0 0 634008 0 0 459104 0 0 0 0 0 0 0 0 0 0 605251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692825 0 0 0 0 472806 0 0 828370 0 0 0 0 0 0 0 0 0 0 549222 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775926 0 0 0 0 532043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388925 0 0 0 0 0 0 0 0 0 0 2451449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1832046 0 0 0 0 632280 +AAGVSVITDGGAPGAGATIR MGYG000001337_03660;MGYG000000236_00420 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FP9Q@200643|Bacteroidia,4ANGT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 ko:K21573 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14.6.1 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001337_03660 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21573:susC; TonB-dependent starch-binding outer membrane protein SusC 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1117647 0 929376 0 1157942 628187 930353 939486 1110797 860608 0 0 867027 765012 1073900 661354 647404 4294745 921666 0 0 649634 3338190 786407 1107837 1201568 933990 2751268 804020 0 0 0 508230 0 968197 932966 1055693 583162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429234 0 303702 0 0 0 0 0 299656 0 0 0 336319 1443562 0 0 0 0 1288818 0 0 391624 242673 1213319 0 0 0 0 0 0 231613 440838 431900 247623 +AAGVSVQNVSGTFGTAPK MGYG000001461_02869;MGYG000000781_02407;MGYG000003922_00917;MGYG000001306_02322;MGYG000000196_03006;MGYG000001378_00321;MGYG000001345_03478;MGYG000001666_01700;MGYG000003221_02259;MGYG000000196_04938 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG4206@1|root,COG4206@2|Bacteria,4P258@976|Bacteroidetes,2FW53@200643|Bacteroidia,4AV2B@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 P 0.9 TonB-linked outer membrane protein, SusC RagA family 0.9 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001461_02869 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 291780 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328643 0 0 958159 0 840578 0 0 0 960306 0 0 0 1399132 0 0 1352280 0 0 0 954736 0 0 0 0 1253394 0 0 824196 972554 1445371 0 0 0 0 822316 0 0 993865 1016264 928934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408115 193845 0 0 0 0 0 0 0 0 0 418034 0 +AAGVTAVSTSGAPGSSSSIR MGYG000001346_02430 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4AWF7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 MGYG000001346_02430 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571921 0 0 0 0 555013 0 0 0 0 366380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1160865 0 0 0 0 812147 0 0 0 0 946048 0 0 0 0 0 0 0 0 0 0 +AAGVVSALAQNAR MGYG000003170_00069;MGYG000001410_00795 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella 1.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,2VRAK@28216|Betaproteobacteria,4PQXX@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 - 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003170_00069 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGVYIGQTGSPGSPSMVR MGYG000002438_03064 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22XE6@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 MGYG000002438_03064 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 204833 305918 0 0 0 0 0 0 0 0 0 0 0 0 0 247708 0 0 0 460101 0 0 306583 0 0 0 0 0 0 0 0 0 346323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470322 846196 464887 0 748216 657133 0 464112 0 0 0 585576 425539 0 332950 0 293893 0 493530 527945 949024 441783 0 355369 232202 272501 358777 0 501966 782117 673536 766417 344394 0 0 0 488996 429493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341333 0 0 0 0 0 0 0 0 361651 0 0 0 0 889492 1621699 754522 0 1947559 1127704 0 848667 862281 0 0 1633478 1127440 0 460236 0 1227285 0 1047663 1048590 5098555 653907 0 1268981 1000780 1001439 975145 0 861320 5656599 1175195 3257185 697252 890719 0 0 1393081 939877 +AAGYDFS(Ser->Gly)GDK MGYG000002492_00484 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 ABC transporter, solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00484 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K15770:cycB, ganO, mdxE; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4742523 0 0 0 0 2463220 0 0 0 0 3640440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGYDKPFK MGYG000002494_02275;MGYG000002534_00118;MGYG000002477_00485;MGYG000002515_03781 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0451@1|root,COG0451@2|Bacteria,1MVE4@1224|Proteobacteria,1RP2S@1236|Gammaproteobacteria,3X0JI@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 GM 1.0 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose 1.0 hldD 1.0 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008712,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901576,GO:1903509 1.0 5.1.3.20 1.0 ko:K03274 1.0 ko00540,ko01100,map00540,map01100 1.0 M00064 1.0 R05176 1.0 RC01291 1.0 ko00000,ko00001,ko00002,ko01000,ko01005 1.0 - 1.0 - 1.0 iPC815.YPO0058,iYL1228.KPN_03963 1.0 Epimerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02275 0.25 ADP-glyceromanno-heptose 6-epimerase. ADP-L-glycero-D-manno-heptose 6-epimerase. - ADP-D-glycero-beta-D-manno-heptose = ADP-L-glycero-beta-D-manno-heptose. 1.0 1.0 1.0 1.0 Lipopolysaccharide biosynthesis|Metabolic pathways 1.0 K03274:gmhD, rfaD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20] 1.0 none 1.0 278777 0 0 0 0 204554 0 0 177526 0 0 0 0 0 0 0 0 0 0 0 0 322068 0 478451 0 230462 0 0 0 0 0 0 0 0 0 0 254515 0 606756 0 0 0 0 978685 0 0 543884 0 0 0 0 0 0 0 0 0 0 0 0 1000239 0 810747 0 338154 0 0 0 0 0 0 0 0 0 0 470639 0 279380 0 0 0 0 596702 0 0 366534 0 0 0 0 0 0 0 0 0 0 0 0 561684 0 465123 0 262813 0 0 0 0 0 0 0 0 0 0 273078 0 240681 0 0 0 0 404550 0 0 276604 0 0 0 0 0 0 0 0 0 0 0 0 351215 0 419500 0 237898 0 0 0 0 0 0 0 0 0 0 0 0 428341 0 0 0 0 0 0 0 1239679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427645 0 734346 0 0 0 0 0 0 0 0 0 0 722380 0 +AAGYDNLK MGYG000002993_00071;MGYG000002143_01292;MGYG000000370_02054;MGYG000002720_01579;MGYG000002156_00957 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,2N727@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002993_00071 0.2 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Vitamin B6 metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00831:serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52] 1.0 none 1.0 0 0 1149556 0 0 0 2771059 0 0 0 0 0 0 0 0 0 0 1501706 0 0 0 0 1679203 0 0 0 0 953661 0 0 0 0 1027248 1784239 0 0 0 1074082 0 0 0 0 0 0 306561 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 648409 0 0 0 0 372891 0 0 986505 0 0 0 1075242 0 0 0 0 0 0 0 0 0 0 895469 0 0 0 0 1083860 0 0 0 0 981978 0 0 0 0 688815 936078 0 0 0 939538 0 0 0 0 0 0 1689366 0 0 0 0 0 0 0 0 0 0 2414306 0 0 0 0 0 0 0 0 0 2272422 0 0 0 0 2163236 1659909 0 0 0 0 0 0 264858 0 0 0 405523 0 0 0 0 0 0 0 0 0 0 316888 0 0 0 0 204967 0 0 0 0 127302 0 0 0 0 297336 0 0 0 0 247084 +AAGYDNLKGHK MGYG000004831_00839;MGYG000002720_01579 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,2N727@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004831_00839 0.5 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Vitamin B6 metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00831:serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGYDVELTYSDNETDR MGYG000000212_01149 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3Y2A7@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Periplasmic binding protein domain 1.0 - 1.0 - 1.0 - 1.0 ko:K10546 1.0 ko02010,map02010 1.0 M00216 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.2.5 1.0 - 1.0 - 1.0 Peripla_BP_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01149 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10546:chvE; putative multiple sugar transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1152686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGYELGK MGYG000002515_00276;MGYG000002506_02347;MGYG000000093_02751;MGYG000002507_03714;MGYG000001464_01969;MGYG000002494_04436;MGYG000000235_01674 domain d__Bacteria 1.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,3XNNK@561|Escherichia 0.8571428571428571 1236|Gammaproteobacteria 0.8571428571428571 F 0.8571428571428571 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 0.8571428571428571 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 iPC815.YPO3376 0.8571428571428571 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000002515_00276 0.14285714285714285 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 759660 968842 621487 1024352 749907 3509305 1581069 1188172 1187759 1346183 641609 915082 734935 1500735 1441926 735266 929730 0 1069798 1360125 1607950 4179837 0 4828844 1272009 1016468 1382134 0 1244145 1497973 776828 726941 1353879 1561332 1340730 1117942 1328086 1459456 15538179 16857005 20127186 13000344 15111457 28978195 14904906 12165107 16216091 16435398 3875292 10732526 0 15768830 10752708 10089018 20758238 0 21124429 12601651 18673449 28911940 0 24050074 17199055 13055211 10063295 0 23150899 17419687 7704218 8968121 20117736 12706976 12447599 11676049 11661575 17240593 2203241 1901110 2134631 1584408 1783850 4792391 0 2070056 2262293 2528279 1287004 1282892 1553958 1577344 2600854 2067877 2061708 0 2118683 2329392 2441220 4274392 0 4829182 2321813 2102084 2522569 0 1673914 2085827 1477076 1309006 2237664 2446939 1564917 2301642 1575965 2072253 4311949 2542729 3684037 3665312 2489956 4484284 5929771 3883077 3171416 4049400 1885653 3891533 2576953 3968964 2868315 2586365 3360058 0 2749359 4364099 3665850 5415011 0 4360515 3907643 2556674 3720398 0 3901701 3263338 1908605 2487598 3275004 4383338 4705550 5060147 2686960 3238514 360340 563868 698107 153754 586592 446839 831373 632618 518288 677402 292064 530556 774685 809794 821119 330196 932881 0 1079345 583782 844926 400096 0 349096 507147 510597 347496 0 324239 394982 542572 410920 941374 675161 503502 846027 643019 542936 +AAGYELGKDITLA MGYG000002515_00276;MGYG000002494_04436 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,3XNNK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 iPC815.YPO3376 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000002515_00276 0.5 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 511799 0 0 0 0 0 0 0 0 0 0 0 372118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4501481 0 0 0 0 0 0 0 0 0 0 0 7757786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1080601 0 0 0 0 0 0 0 0 0 0 0 828861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1626555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGYELGKDITLAM(Oxidation)DC(Carbamidomethyl)AASEFYKDGK MGYG000002506_02347;MGYG000002494_04436 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,3XNNK@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 1.0 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 iPC815.YPO3376 1.0 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000002506_02347 0.5 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 0 0 0 0 0 358218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262622 0 558167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1734750 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3491792 0 1571522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1665205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGYFNPFLEPMME(Glu->Lys) MGYG000000099_02239 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,267NE@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_02239 1.0 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K01844:kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1782176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGYLWNPLTGVYLFPR MGYG000002478_01405 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKS4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01405 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4212405 2305470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1511257 0 0 0 0 0 0 1249242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5034425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAGYTNIEFHK MGYG000002494_04286;MGYG000002535_00504;MGYG000002534_04100;MGYG000003372_04662;MGYG000002506_02507;MGYG000002477_01454 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0111@1|root,COG0111@2|Bacteria,1MU5Z@1224|Proteobacteria,1RPEY@1236|Gammaproteobacteria,3ZJFX@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 EH 1.0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 1.0 serA 1.0 GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008219,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0012501,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.1.1.399,1.1.1.95 1.0 ko:K00058 1.0 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 1.0 M00020 1.0 R01513 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iYL1228.KPN_03348 1.0 2-Hacid_dh,2-Hacid_dh_C,ACT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04286 0.16666666666666666 2-oxoglutarate reductase. | phosphoglycerate dehydrogenase. phosphoglyceric acid dehydrogenase. The enzyme catalyzes a reversible reaction.-!-The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate.-!-The SerA enzyme from Escherichia coli can also accept (S)-2- hydroxyglutarate with a much higher Km, and also catalyzes the activity of EC 1.1.1.95. | Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis.-!-The reaction occurs predominantly in the direction of reduction.-!-The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399. (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + H(+) + NADH. | (2R)-3-phosphoglycerate + NAD(+) = 3-phosphooxypyruvate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00058:serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399] 1.0 none 1.0 304150 220847 406956 0 176026 498300 186886 0 217309 311424 0 166682 175471 276856 172508 182714 188659 0 320472 78208 100572 640860 0 701886 297466 142432 0 0 155076 133566 174010 165316 408985 374980 179335 254546 152694 238417 2938395 6009725 6165886 0 5048526 8447694 3447567 0 2306021 3476204 0 2452277 3648262 2934673 1980619 5418647 6232207 0 4184281 2066912 6566749 11603041 0 7936122 4477180 2155955 0 0 6602100 5360444 2512454 2548187 6287690 1881728 1719616 2631670 1966800 5724294 188020 205284 150252 0 162808 559027 95934 0 150403 177523 0 0 0 125634 219773 0 257861 0 0 161139 154726 491860 0 592305 76577 193566 0 0 0 103296 57631 73432 175146 75591 125192 103522 134128 130769 1138121 294506 693290 0 491567 796380 1372097 0 718079 676024 0 386984 435645 839446 782793 683041 685557 0 599301 955587 1401375 976053 0 771783 1178513 852643 0 0 507957 798341 472607 275509 680175 1352472 1495348 1554239 607244 600133 69600 58785 53626 0 71212 169772 0 0 194887 179410 0 85981 0 0 233638 0 172186 0 0 180229 0 156686 0 63866 0 0 0 0 0 0 86390 0 0 366157 0 0 70836 200508 +AAGYTSEPHAAVAYR MGYG000002494_02907 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0083@1|root,COG0498@1|root,KOG1537@2759|Eukaryota,KOG2616@2759|Eukaryota,38DB9@33154|Opisthokonta,3BI93@33208|Metazoa,3D0F1@33213|Bilateria,420W7@6656|Arthropoda,3SQID@50557|Insecta 1.0 33208|Metazoa 1.0 E 1.0 Threonine synthase N terminus 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02907 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94809 0 0 0 0 0 0 0 0 0 0 0 0 209545 0 1054643 1372825 1261067 0 1277582 2120830 0 0 0 0 0 0 0 1354882 0 0 1511219 0 1162044 671029 1625646 2371140 0 1929778 1215085 763497 0 0 1528236 1012562 0 0 1283055 0 0 0 681229 1401742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAHAD(Methyl[D](Asp->Glu)TLAAK MGYG000000205_02694;MGYG000000233_02509 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,2PR0E@265975|Oribacterium 1.0 186801|Clostridia 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02694 0.5 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 778880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 540631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAHADTLAAK MGYG000000205_02694;MGYG000000233_02509 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,2PR0E@265975|Oribacterium 1.0 186801|Clostridia 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02694 0.5 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 252470 267577 123160 312029 240883 0 236575 178901 314333 262154 387231 244018 0 0 0 261042 349374 0 0 0 0 0 0 0 384200 238055 494752 0 0 0 0 366477 210403 325630 232153 244037 135690 218574 1163842 1218966 828334 1194157 1253762 0 1435798 1229965 841741 1239856 1195489 1474621 0 0 0 1214550 1376420 0 0 0 0 0 0 0 1059571 1130356 1363434 0 0 0 0 1371916 577023 1194461 840189 893454 829315 901763 0 0 0 63105 29231 0 0 34461 61601 69611 0 0 0 0 0 56383 55191 0 0 0 0 0 0 0 96746 56817 91357 0 0 0 0 0 0 105596 51411 65133 51653 0 163965 126513 52079 194453 149057 0 67700 36608 122081 0 82544 125163 0 0 0 157111 118567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 61858 36079 92934 113294 83950 87394 43744 126519 286233 177365 141463 234496 0 272149 170652 134934 250802 228079 175616 0 0 0 164795 55463 0 0 0 0 0 0 0 147847 70336 157866 0 0 0 0 128378 267935 175801 110098 83764 111018 142976 +AAHAETLAAK MGYG000000255_02201 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,2PR0E@265975|Oribacterium 1.0 186801|Clostridia 1.0 EH 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_02201 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 643968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAHAQDMVTGFIR MGYG000004735_00145 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Carboxyl_trans 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00145 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2651835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 846877 0 0 0 0 0 0 +AAHDAIKIHC(Carbamidomethyl)K MGYG000000243_02576 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000243_02576 1.0 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAHEAIKVHC(Carbamidomethyl)K MGYG000004797_03519;MGYG000002478_00894 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004797_03519 0.5 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 639733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98034 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAHFGNNVSHSHR MGYG000000184_00823;MGYG000001338_01758 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL28 family 1.0 rpmB 1.0 - 1.0 - 1.0 ko:K02902 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_00823 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02902:RP-L28, MRPL28, rpmB; large subunit ribosomal protein L28 1.0 none 1.0 0 0 201539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283862 686633 37966 0 0 0 0 51365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2074437 123318 0 0 0 0 0 0 0 0 85070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342585 513063 159242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54209 0 0 0 0 0 0 0 0 385252 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1253552 721594 787132 0 0 0 0 166384 +AAHFGNNVSHSHRR MGYG000000184_00823;MGYG000001338_01758 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL28 family 1.0 rpmB 1.0 - 1.0 - 1.0 ko:K02902 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_00823 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02902:RP-L28, MRPL28, rpmB; large subunit ribosomal protein L28 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 955365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAHFITLVPK MGYG000002478_04295 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1359@1|root,COG1359@2|Bacteria,4NUHJ@976|Bacteroidetes,2FT37@200643|Bacteroidia,4ARA5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Antibiotic biosynthesis monooxygenase 1.0 ycnE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ABM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_04295 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 776108 0 0 0 0 0 0 0 0 0 0 1137521 0 540705 0 0 0 0 886257 0 0 0 0 669453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789387 0 0 0 0 0 0 0 0 0 0 1156274 0 52949 0 0 0 0 604904 0 0 0 0 503887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312457 0 0 0 0 0 0 0 0 0 0 488083 0 427159 0 0 0 0 408887 0 0 0 0 330131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 695175 0 0 0 0 0 0 0 0 0 0 493374 0 1175672 0 0 0 0 924198 0 0 0 0 758476 0 0 0 0 0 0 0 0 0 0 +AAHFVTLVPK MGYG000000243_01283 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1359@1|root,COG1359@2|Bacteria,4NUHJ@976|Bacteroidetes,2FT37@200643|Bacteroidia,4ARA5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Antibiotic biosynthesis monooxygenase 1.0 ycnE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ABM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01283 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 745949 0 0 0 0 0 0 0 0 0 0 455574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 889415 0 0 0 0 827603 0 0 423621 0 0 0 0 0 0 0 0 0 0 416797 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308774 0 0 0 0 428659 0 0 389825 0 0 0 0 0 0 0 0 0 0 333753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262288 0 0 0 0 359364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAHLPEQM(Oxidation)IQNIAK MGYG000002281_00012;MGYG000001346_00649;MGYG000000013_03147;MGYG000004876_02408;MGYG000004019_01939;MGYG000001661_02572;MGYG000002549_00046;MGYG000001378_03196;MGYG000001313_02981;MGYG000003252_02162;MGYG000002455_03779;MGYG000001345_01370;MGYG000000196_04091;MGYG000003681_02139;MGYG000000029_01191 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_00012 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 454980 0 0 558723 224546 0 0 245580 0 401525 545121 0 0 0 1097364 1082540 453451 0 0 0 706380 384024 252297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 333106 0 0 187852 229005 0 0 1184443 0 722635 474481 0 0 0 292201 292036 331139 0 0 0 220768 0 193405 0 0 0 271478 0 0 0 0 0 0 0 0 0 0 0 761741 0 0 720756 791518 0 0 713405 0 1078595 514423 0 0 0 611635 784703 1038655 0 0 0 458240 827078 808805 0 0 0 667597 0 0 0 0 0 0 0 0 0 0 0 448202 0 0 367300 599317 0 0 320042 0 460058 244358 0 0 0 708092 463482 355059 0 0 0 367081 488129 392647 0 0 0 460702 0 0 0 0 0 0 0 0 0 0 0 303919 0 0 557226 577092 0 0 303140 0 1024455 137674 0 0 0 313542 233390 327152 0 0 0 534402 290462 369012 0 0 0 229278 0 0 0 0 0 0 0 0 0 0 +AAHLPEQMIQNIAK MGYG000002281_00012;MGYG000001346_00649;MGYG000000013_03147;MGYG000004876_02408;MGYG000004019_01939;MGYG000001661_02572;MGYG000002549_00046;MGYG000001378_03196;MGYG000001313_02981;MGYG000003252_02162;MGYG000002455_03779;MGYG000001345_01370;MGYG000000196_04091;MGYG000003681_02139;MGYG000000029_01191 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_00012 0.06666666666666667 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 4489921 5288466 3665177 5387890 3764832 3710884 7794139 4502736 5240299 4368123 10218183 4910571 3548056 1666515 3955008 4241313 4526733 1020270 1280491 3558348 3892002 3389563 2724850 5960550 3675756 4400502 4509279 1784086 4499975 4542666 0 5239079 0 5538060 3638490 4532824 1797288 3409131 7479260 3951304 7332182 8098628 6361962 8809529 7451574 9812649 7650966 11288926 14804582 9204102 6863619 10231100 9441213 10559906 7843109 2299224 7515448 7567636 7382216 10066556 3084094 6843285 8084933 9617064 8822803 2315274 6948548 6986512 5692588 8358904 7577040 7651246 8205374 7867523 8709343 7939885 3626177 3390211 6302466 3640947 5897309 5383004 6004721 3948342 5903916 3228646 9633084 5242997 3131762 4518705 2804137 4819852 4245204 7653048 3113110 3794824 4230267 3705013 5798756 5486072 3213852 3528283 3278140 6114637 5012945 4346962 4905064 3442781 4115077 3523653 3550028 5827956 3993819 5227325 4004730 2744599 3450520 2872227 3874755 3699297 4370611 4111021 3497054 3295940 5980604 4555999 4798376 3923617 3988025 4653633 3293134 3020288 3530592 3331603 5336996 2617078 3997126 1895746 4463651 4905048 4308231 1035357 2706340 3862099 3035184 4522679 3759724 4554615 4637223 5750978 4861538 2675726 4008857 3406812 3241150 4065526 5150093 6336608 4541029 4244000 4502905 3404954 11721701 3714461 5523007 2624398 3847800 5005676 4049539 4778879 3045580 5449378 2902402 4805387 3509695 5259934 3855793 4247456 3178078 4468820 3590157 5796141 3801106 3522922 2349755 4501073 3690214 3562798 4517327 4031972 +AAHPNWDLTFK MGYG000001319_02248 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia,4BYAS@830|Butyrivibrio 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K15770 1.0 ko02010,map02010 1.0 M00491 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.16,3.A.1.1.2 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001319_02248 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K15770:cycB, ganO, mdxE; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1128904 0 0 0 0 825458 0 0 0 0 1442119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1953248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858678 0 0 0 0 545365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3731432 0 0 0 0 2213869 0 0 0 0 0 0 0 0 0 0 +AAHSFNLLDAR MGYG000002477_00434;MGYG000002534_00166;MGYG000003372_03454;MGYG000002535_04458;MGYG000002494_02222;MGYG000002515_03452;MGYG000002506_03203 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0752@1|root,COG0752@2|Bacteria,1MVCJ@1224|Proteobacteria,1RMYI@1236|Gammaproteobacteria,3X0QV@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 J 1.0 glycyl-tRNA synthetase alpha subunit 1.0 glyQ 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 6.1.1.14 1.0 ko:K01878 1.0 ko00970,map00970 1.0 M00360 1.0 R03654 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iAF1260.b3560,iJO1366.b3560,iPC815.YPO4072,iY75_1357.Y75_RS19360 1.0 tRNA-synt_2e 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002477_00434 0.14285714285714285 glycine--tRNA ligase. glycyl-tRNA synthetase. - ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01878:glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14] 1.0 none 1.0 0 0 108279 0 0 111352 0 0 0 97013 0 0 0 0 0 0 0 0 0 0 73942 229665 0 132084 34804 0 0 0 126313 116208 0 0 0 0 0 0 0 0 0 0 672205 0 606802 888333 0 0 0 891740 0 0 0 611893 0 0 765485 0 700670 0 866547 1062279 0 853362 801257 0 0 0 899082 740896 0 0 753252 0 0 0 0 569851 0 0 132170 0 246536 502493 0 0 0 246944 0 0 0 199106 0 0 216929 0 52835 0 237383 512623 0 514676 226307 0 0 0 106464 157077 0 0 174913 0 0 0 0 165545 0 0 79207 0 155520 76685 0 0 0 63172 0 0 0 65556 0 0 93279 0 105449 0 125803 86330 0 71706 0 0 0 0 82775 138774 0 0 141029 0 0 0 0 205457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAHSVANAVSK MGYG000004769_00967 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,4H2B2@909932|Negativicutes 1.0 909932|Negativicutes 1.0 S 1.0 TRAP transporter solute receptor TAXI family 1.0 - 1.0 - 1.0 - 1.0 ko:K07080 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 NMT1_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_00967 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07080:K07080; uncharacterized protein 1.0 none 1.0 0 36310 150499 0 222694 177188 0 222420 0 0 454724 88740 0 0 0 0 0 0 136380 194651 0 63278 0 372019 0 0 0 0 0 0 0 0 251288 0 247056 0 0 143720 0 1259777 1370884 0 2193505 2173092 0 1796281 0 0 2289529 1487351 0 0 0 0 0 0 1464929 929648 0 1895930 0 1485858 0 0 0 0 0 0 0 0 1213448 0 798808 0 0 774615 0 855660 642347 0 429584 605680 0 717800 0 0 675002 165673 0 0 0 0 0 0 643858 779863 0 830387 0 642747 0 0 0 0 0 0 0 0 574742 0 619380 0 0 564419 0 142713 104832 0 85655 146114 0 127264 0 0 259616 94673 0 0 0 0 0 0 321305 93920 0 220233 0 178132 0 0 0 0 0 0 0 0 383792 0 116070 0 0 160003 0 69539 58845 0 0 27235 0 40839 0 0 0 35389 0 0 0 0 0 0 67855 85763 0 38735 0 0 0 0 0 0 0 0 0 0 103187 0 128914 0 0 83081 +AAI(Xle->Val)DNSYNVLR MGYG000002935_00389;MGYG000000243_01847;MGYG000002478_01470 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002935_00389 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03072:secD; preprotein translocase subunit SecD|K12257:secDF; SecD/SecF fusion protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1571373 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAI(Xle->Val)GIPEEELR MGYG000000196_04526;MGYG000000029_01860;MGYG000001345_00467;MGYG000003367_00149;MGYG000000044_01913;MGYG000002033_00099;MGYG000002478_01776;MGYG000002905_01187;MGYG000000243_02506;MGYG000001306_00718;MGYG000003221_00520;MGYG000002455_03337;MGYG000000174_01424;MGYG000000355_00809;MGYG000004797_01374;MGYG000000273_02673;MGYG000002575_01735 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.5294117647058824 976|Bacteroidetes 1.0 G 0.6470588235294118 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.5294117647058824 fba 0.6470588235294118 - 1.0 4.1.2.13 0.6470588235294118 ko:K01624 0.6470588235294118 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6470588235294118 M00001,M00003,M00165,M00167,M00344,M00345 0.6470588235294118 R01068,R01070,R01829,R02568 0.6470588235294118 RC00438,RC00439,RC00603,RC00604 0.6470588235294118 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6470588235294118 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04526 0.058823529411764705 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6470588235294118 0.6470588235294118 0.6470588235294118 0.6470588235294118 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6470588235294118 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 0.6470588235294118 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5406843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAI(Xle->Val)YSGEK MGYG000001780_00304;MGYG000004876_01447;MGYG000002478_02197 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 MGYG000001780_00304 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2209580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIAAAC(Carbamidomethyl)QTK(Lys->Arg) MGYG000003921_00859 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3WGMD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_00859 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7433983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIAAAEGDYK MGYG000004658_01702;MGYG000000074_00133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004658_01702 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 801646 608804 383570 780187 727167 0 857841 0 549083 171498 466344 571245 219052 365564 360958 0 594455 0 0 675858 865588 0 0 415820 346107 510354 656933 0 544020 637160 276887 586219 189628 180045 451514 720129 497138 264010 2529798 1562036 2406682 0 2095531 1382622 1404001 0 2714231 2606687 1418615 0 1258559 2763659 2761833 2217658 2300091 0 2832516 3699713 2579151 1891920 0 1541365 1794772 2727983 0 0 0 2010571 1913231 2040495 0 2712974 2789001 2524268 0 2208945 447989 212011 603268 328203 507256 0 439640 372244 514652 484353 364094 252611 0 452293 355492 0 311490 0 3857680 223977 422210 0 0 0 281558 0 439258 0 267160 520843 414419 0 0 0 445571 526366 404809 0 1521087 1109344 1657418 1295773 1161341 1181215 1850183 1309176 1549297 1291816 1243700 1712396 1478906 1314501 1754779 928096 1163540 0 1850877 1530962 2012607 690718 0 817894 1959667 2265270 1193725 0 1440048 1546736 1064374 1767787 1684068 0 1345309 2294184 1754061 872761 13291255 11090158 12082389 24238075 18544207 18322139 15888811 10785072 16952914 12110487 10544233 17599658 15868490 9086203 12403568 14563658 21586052 0 15603425 27395047 11243435 11378715 0 14134481 13444073 28495704 11848963 0 11233509 25864877 11907800 11915708 8096152 744408 14716813 29270637 18955390 12750384 +AAIAAAQANPNAK MGYG000002506_03879;MGYG000003360_01349;MGYG000002515_04072;MGYG000000107_04045;MGYG000002534_04395;MGYG000002494_02689;MGYG000002535_03828;MGYG000002323_03811 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,1RMU2@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily 1.0 frdA 1.0 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.0 1.3.5.4 1.0 ko:K00244 1.0 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 1.0 M00009,M00011,M00150,M00173 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECIAI39_1322.ECIAI39_4621,iEcSMS35_1347.EcSMS35_4625,iPC815.YPO0360 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_03879 0.125 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Two-component system 1.0 K00244:frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 1245469 811598 522790 865862 0 720295 1312164 1191801 697200 927451 320611 736950 260484 907222 187552 213405 598950 0 1215767 395195 861590 1185402 0 1202788 521355 1294518 920859 0 1067872 963957 0 722806 436194 680400 1129903 932852 820560 584674 3052606 3496507 3064766 3035657 0 5607835 3166342 0 2050416 4269336 4112162 2650013 1539483 2734195 2464229 1814731 3659885 0 3412436 0 3423091 5840175 0 4444776 3054219 2604074 3112022 0 4199355 3046077 0 3376840 3436990 3564527 3002279 2782096 2557796 2468011 1175261 1882105 1245701 1292628 0 2834219 2344974 2028056 1257160 2591491 3004635 2064933 1746817 1508088 1518387 2218303 2366106 0 1774624 1604022 1970289 1930374 0 1435147 1998394 1092084 1279674 0 2025796 1974162 0 1075099 1880145 1541518 1823703 1645580 1052256 900860 171697 1421939 1532739 438232 0 1330127 0 325351 906987 1718173 1660752 1639526 1413601 506393 1216571 1142606 1016233 0 1021281 542626 312641 293268 0 800669 253311 119458 1218581 0 2209530 1231615 0 2200224 1151723 821911 961495 1222508 636790 900311 0 287304 163518 163001 0 137188 1061927 185417 0 0 2050604 170615 160831 190263 243160 107179 0 0 0 0 0 0 0 194358 109216 0 0 0 0 0 0 173837 351573 203364 141810 0 0 0 +AAIAADK MGYG000002438_01767;MGYG000001489_01457 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG3063@1|root,COG3063@2|Bacteria,4PKG6@976|Bacteroidetes,2G3G2@200643|Bacteroidia,2322F@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 NU 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01767 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 878160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIAADKAMAK MGYG000000138_03130;MGYG000000044_02742 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG3063@1|root,COG3063@2|Bacteria,4PKG6@976|Bacteroidetes,2G3G2@200643|Bacteroidia,2322F@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 NU 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000138_03130 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 474551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 538438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIAADKFQR MGYG000002218_00670 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides sp000436495|m__MGYG000002218 1.0 COG3063@1|root,COG3063@2|Bacteria,4PKG6@976|Bacteroidetes,2G3G2@200643|Bacteroidia,2322F@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 NU 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002218_00670 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2078349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 414432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIAAEGTPAEYK MGYG000004479_01116;MGYG000000042_02678;MGYG000000781_02114;MGYG000001835_01025;MGYG000004763_00186 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 0.8 MGYG000004479_01116 0.2 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 500155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 946896 0 0 0 0 1653584 0 0 896439 0 0 0 0 1088054 3857523 0 0 0 0 5308798 0 0 0 0 4823404 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 615363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2718469 0 0 0 0 2066235 0 0 0 0 1844579 0 0 0 0 0 0 0 0 0 0 +AAIAAGADGLMIEVHPC(Carbamidomethyl)PAK MGYG000000179_03817 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,21YS6@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 8.87 1.0 aroF 1.0 - 1.0 2.5.1.54 1.0 ko:K03856 1.0 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 1.0 M00022 1.0 R01826 1.0 RC00435 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAHP_synth_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03817 1.0 3-deoxy-7-phosphoheptulonate synthase. phospho-2-oxo-3-deoxyheptonate aldolase. Formerly EC 4.1.2.15. D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-phospho-2- dehydro-3-deoxy-D-arabino-heptonate + phosphate. 1.0 1.0 1.0 1.0 Phenylalanine, tyrosine and tryptophan biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K03856:AROA2, aroA; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683493 0 0 0 0 0 0 0 0 0 +AAIAAGAPK MGYG000002506_00529;MGYG000001692_01757 order d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,1RNBH@1236|Gammaproteobacteria,3XMER@561|Escherichia 0.5 1236|Gammaproteobacteria 0.5 C 1.0 This enzyme has three activities ADH, ACDH, and PFL- deactivase. In aerobic conditions it acts as a hydrogen peroxide scavenger. The PFL deactivase activity catalyzes the quenching of the pyruvate-formate-lyase catalyst in an iron, NAD, and CoA dependent reaction 0.5 adhE 0.5 GO:0003674,GO:0003824,GO:0004022,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006067,GO:0006115,GO:0008150,GO:0008152,GO:0008774,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016620,GO:0016903,GO:0016999,GO:0017000,GO:0017144,GO:0034308,GO:0034309,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0055114,GO:0071704,GO:1901576,GO:1901615,GO:1901617 0.5 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iEcE24377_1341.EcE24377A_1389,iYL1228.KPN_02199 0.5 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00529 0.5 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 455007 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766224 0 597662 0 0 0 0 0 0 0 0 0 0 0 0 0 149299 0 0 1061274 0 0 1035427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460834 0 288100 0 0 0 0 0 0 0 0 964975 0 0 667322 0 711575 0 0 1033755 0 0 3101189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2090251 0 2930755 0 0 0 0 0 0 0 0 1131990 0 0 791570 0 990111 0 0 3289709 0 0 2414850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5180097 0 5170649 0 0 0 0 0 0 0 0 2319453 0 0 1658184 0 3424125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIADGNEDAK MGYG000000212_00407 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_00407 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 0 0 0 0 631242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 967540 0 438947 0 0 0 0 1385528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421193 0 0 0 0 0 0 0 0 0 0 632145 0 0 0 0 493262 0 581003 0 0 0 0 768863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 567497 0 0 0 0 0 0 0 0 0 0 803512 0 0 0 0 576064 0 403415 0 0 0 0 3077100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIADLEKAEDSAK MGYG000002492_01714 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3XZ0G@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate 1.0 argJ 1.0 - 1.0 2.3.1.1,2.3.1.35 1.0 ko:K00620 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028 1.0 R00259,R02282 1.0 RC00004,RC00064 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ArgJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01714 1.0 amino-acid N-acetyltransferase. | glutamate N-acetyltransferase. N-acetylglutamate synthase. | ornithine transacetylase. Also acts with L-aspartate and, more slowly, with some other amino acids. | Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity. acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate. | L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L- glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00620:argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] 1.0 none 1.0 179451 0 101899 0 0 0 314925 0 0 201759 0 0 388058 0 0 80039 70266 229309 186606 0 0 0 152529 0 252870 172635 0 159733 0 88071 233437 0 0 0 305912 0 195337 0 369623 0 1274220 582742 1270107 324633 580855 392050 0 0 1008236 413858 318011 337476 0 308132 0 3271417 0 0 0 288614 1406886 300632 415450 427586 172985 2423554 0 285993 695382 531018 1133120 241707 375916 458256 271190 1652889 1047232 0 5424798 1122220 1572352 842605 1122715 1124230 908987 1358758 2345986 2224084 2588442 1114785 0 2663556 1195699 841138 1205047 0 0 1004478 1193532 765976 1431837 1373377 1481794 1333481 0 1208422 1995040 979958 5355157 1519783 1501048 908243 1277151 4693854 314011 0 0 0 0 0 0 0 337195 134544 234190 0 164019 84733 0 284223 228057 0 0 0 0 0 0 130230 0 310080 0 0 0 324561 459022 152768 389886 101702 334997 0 0 437498 0 0 0 0 320484 0 0 228605 0 0 0 0 85065 0 0 0 0 0 0 0 0 0 0 0 182457 0 0 0 0 90967 0 536729 0 214964 0 0 0 0 +AAIADLTEAGVR MGYG000001365_01213;MGYG000000591_01067 genus d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A 1.0 COG0346@1|root,COG0346@2|Bacteria,1V6SC@1239|Firmicutes,4H40Q@909932|Negativicutes 1.0 909932|Negativicutes 1.0 E 1.0 methylmalonyl-CoA epimerase 1.0 mce 1.0 - 1.0 5.1.99.1 1.0 ko:K05606 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R02765,R09979 1.0 RC00780,RC02739 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glyoxalase_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001365_01213 0.5 methylmalonyl-CoA epimerase. methylmalonyl coenzyme A racemase. - (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K05606:MCEE, epi; methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] 1.0 none 1.0 0 0 435080 161981 0 249627 467093 540335 585050 0 0 0 0 0 0 0 0 0 834644 482973 0 0 0 443883 0 361193 0 473401 0 0 133760 0 414300 369376 255705 0 0 216969 0 0 0 314784 0 0 0 0 242340 0 0 0 0 0 0 0 292928 919016 0 0 0 0 0 0 0 0 0 920269 0 0 169003 0 0 0 0 0 0 309232 0 0 0 0 310168 435718 312098 490120 315587 222583 272773 453568 0 0 0 226810 327131 0 0 286935 0 0 1496659 286151 0 408104 0 542020 283094 0 360814 504543 0 321452 0 0 0 120497 0 0 387662 0 261415 392434 0 0 0 0 377802 447078 400895 0 634780 0 461334 850839 634862 0 0 0 962372 362588 0 0 0 895828 0 658054 515322 467685 607904 624812 0 0 0 453532 0 0 12421604 16382784 11970696 17210469 9044165 15640280 10954789 7331293 11696448 8687790 10916706 0 8708825 6393202 9176087 16914920 10303878 10934822 0 16509062 16168373 21511736 0 9011970 0 17133582 10703284 10839331 13956232 17151740 9858486 11960347 15489365 0 10505689 14634083 +AAIADYK MGYG000002506_02049;MGYG000002525_00332;MGYG000002323_03053 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0822@1|root,COG0822@2|Bacteria,1RD5K@1224|Proteobacteria,1S3P1@1236|Gammaproteobacteria,3XPIY@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters 1.0 iscU 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 1.0 - 1.0 ko:K04488 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_3996,iB21_1397.B21_02385,iBWG_1329.BWG_2293,iE2348C_1286.E2348C_2812,iEC042_1314.EC042_2733,iEC55989_1330.EC55989_2814,iECABU_c1320.ECABU_c28350,iECBD_1354.ECBD_1155,iECB_1328.ECB_02421,iECDH10B_1368.ECDH10B_2696,iECDH1ME8569_1439.ECDH1ME8569_2456,iECD_1391.ECD_02421,iECED1_1282.ECED1_2960,iECH74115_1262.ECH74115_3761,iECIAI1_1343.ECIAI1_2581,iECIAI39_1322.ECIAI39_2730,iECNA114_1301.ECNA114_2608,iECO103_1326.ECO103_3046,iECO111_1330.ECO111_3253,iECO26_1355.ECO26_3576,iECOK1_1307.ECOK1_2878,iECP_1309.ECP_2534,iECS88_1305.ECS88_2705,iECSE_1348.ECSE_2815,iECSF_1327.ECSF_2373,iECSP_1301.ECSP_3473,iECUMN_1333.ECUMN_2849,iECW_1372.ECW_m2755,iECs_1301.ECs3395,iEKO11_1354.EKO11_1204,iETEC_1333.ETEC_2686,iEcDH1_1363.EcDH1_1139,iEcE24377_1341.EcE24377A_2814,iEcHS_1320.EcHS_A2680,iEcSMS35_1347.EcSMS35_2682,iEcolC_1368.EcolC_1148,iG2583_1286.G2583_3059,iJO1366.b2529,iSDY_1059.SDY_2725,iSFV_1184.SFV_2577,iSF_1195.SF2576,iSFxv_1172.SFxv_2832,iSSON_1240.SSON_2611,iS_1188.S2748,iUMN146_1321.UM146_04055,iUMNK88_1353.UMNK88_3182,iUTI89_1310.UTI89_C2851,iWFL_1372.ECW_m2755,iY75_1357.Y75_RS13200,iZ_1308.Z3796,ic_1306.c3055 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02049 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04488:iscU, nifU; nitrogen fixation protein NifU and related proteins 1.0 none 1.0 0 0 0 0 0 669788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618130 0 724556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1140601 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1143121 0 910153 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2321462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1555597 0 2344587 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1375720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 512997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIAEDPDYAK MGYG000000164_01266 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0579@1|root,COG2906@1|root,COG0579@2|Bacteria,COG2906@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,25V7H@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 - 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 BON,DAO,Fer2_BFD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_01266 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 1327455 0 0 0 0 0 1754803 1728721 0 2018262 0 0 0 0 1782738 0 0 0 1122642 0 0 0 0 0 1680170 1330369 0 0 0 0 0 0 0 0 0 1150085 1574999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407421 0 0 0 0 0 0 0 0 301167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477552 0 0 0 0 0 0 0 0 609513 0 0 0 0 0 0 646506 0 0 0 0 0 0 0 0 0 337387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156483 0 0 0 0 0 0 1431842 0 0 0 0 0 0 0 0 0 2051862 0 0 +AAIANAR MGYG000003683_00464;MGYG000000756_00775 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00464 0.5 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00616:TALDO1, talB, talA; transaldolase [EC:2.2.1.2] 1.0 none 1.0 0 0 188259 0 0 0 0 0 0 0 0 0 364370 0 0 0 0 71347 0 148818 0 0 62982 0 85271 0 0 66493 0 0 470137 0 0 0 0 0 0 881380 0 0 279143 0 0 0 0 0 0 0 0 0 2358793 0 0 609973 0 1502830 0 295280 0 0 1243113 0 296284 0 0 2239531 0 0 2063069 0 301392 0 0 0 0 585305 0 0 226260 0 0 0 0 0 0 0 0 0 236663 0 0 346015 0 0 0 306116 0 0 159149 0 354551 0 0 350666 0 0 180393 0 832597 0 0 0 0 362068 0 0 52062 0 0 0 0 0 0 0 0 0 162483 0 0 0 0 184017 0 0 0 0 91052 0 43776 0 0 0 0 0 64572 0 62046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 60371 0 68667 0 0 81176 0 0 0 0 102152 0 0 0 0 0 0 0 0 0 70006 +AAIAQIEKPNAE MGYG000000164_02291 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3Y0GK@572511|Blautia 1.0 186801|Clostridia 1.0 U 1.0 COG COG1862 Preprotein translocase subunit YajC 1.0 yajC 1.0 - 1.0 - 1.0 ko:K03210 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2 1.0 - 1.0 - 1.0 Ftsk_gamma,YajC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_02291 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03210:yajC; preprotein translocase subunit YajC 1.0 none 1.0 0 0 0 0 0 0 1219157 0 1362205 0 0 0 0 0 1799189 0 0 0 1036096 0 1692596 0 0 0 0 0 0 0 0 0 0 0 0 971930 1289864 0 0 0 0 0 0 0 0 0 256336 0 357537 0 0 0 0 0 186758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 282796 375646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 490165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIAQVEK MGYG000002992_02024;MGYG000000198_04879;MGYG000001496_02754;MGYG000002279_02611;MGYG000001789_02120 domain d__Bacteria 1.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,27VNQ@189330|Dorea 0.4 186801|Clostridia 0.8 U 0.8 Preprotein translocase subunit 0.8 yajC 0.8 - 1.0 - 0.8 ko:K03210 0.8 ko02024,ko03060,ko03070,map02024,map03060,map03070 0.8 M00335 0.8 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 0.8 3.A.5.1,3.A.5.2 0.8 - 1.0 - 1.0 Ftsk_gamma,YajC 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002992_02024 0.2 - - - - 0.8 0.8 0.8 0.8 Quorum sensing|Protein export|Bacterial secretion system 0.8 K03210:yajC; preprotein translocase subunit YajC 0.8 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2253157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIAVLPATYK MGYG000000243_01881 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG3637@1|root,COG3637@2|Bacteria,4NIPZ@976|Bacteroidetes,2FQ2F@200643|Bacteroidia,4ANBF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 COG NOG32048 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01881 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 2095035 3722034 1842047 2747515 3056136 2503295 2616956 2681354 1972431 2091263 3186122 0 3644691 1910109 1835209 3406017 3181069 0 0 1781265 2368382 1956976 0 3087515 1963890 2546153 2945481 0 0 2519982 3345949 2539637 2462244 2783975 2387249 2428173 2259515 1689178 492384 255058 387132 608476 371423 253427 441960 550649 556308 572459 513877 0 624871 472947 527621 543218 452491 0 0 411597 0 556311 0 530732 279833 0 355032 0 0 370731 316230 368538 359051 321128 400625 309096 402915 435780 498670 865436 267223 332160 678459 460171 422791 180762 246937 270831 230476 0 141938 261509 233094 317044 313062 0 0 0 142953 207942 0 710287 0 300638 308213 0 0 188047 841844 461436 301919 269121 280524 419367 314061 391270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIAYGADEVDVVFPYR MGYG000002494_02883;MGYG000002506_04111;MGYG000002515_04338;MGYG000003390_03926;MGYG000002507_00239;MGYG000000107_03772;MGYG000003365.1_03302 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3ZJCJ@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 F 1.0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 deoA 1.0 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 1.0 2.4.2.4 1.0 ko:K00758 1.0 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 1.0 - 1.0 R01570,R02484,R08222,R08230 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 1.0 Glycos_trans_3N,Glycos_transf_3,PYNP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02883 0.14285714285714285 thymidine phosphorylase. pyrimidine phosphorylase. In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.-!-Formerly EC 2.4.2.23. phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Bladder cancer 1.0 K00758:deoA, TYMP; thymidine phosphorylase [EC:2.4.2.4] 1.0 none 1.0 859828 488261 748279 953961 715617 602100 1118030 1299120 809222 1496784 388232 580670 243314 781367 564036 374875 1002071 0 833740 879051 755416 622201 0 817466 681483 1046367 781400 0 914283 1080829 949231 922283 145131 901546 874643 744737 791903 635743 1036196 1045102 846347 1079680 1357755 1626681 1260302 1288197 1154742 1712054 864402 1285394 737757 1171558 1280624 971376 1684492 0 1331711 950052 1262129 1876057 0 1537903 1353531 1066437 1472985 0 1708423 1004708 733496 1398403 1028652 929633 985320 766733 863498 596484 1119166 1038706 204748 6245 1562093 1228904 1387094 1487554 2686283 1399610 919537 1055119 1087987 1238026 1032640 1052366 865891 0 1037117 1002988 817638 852875 0 2804547 1554037 6955045 1245320 0 1242119 868109 1018623 3253916 1137543 1315470 2416316 3739011 3254211 2200037 4666642 2927271 3765450 3947685 5590184 0 5186409 5923748 4994366 6020285 0 4690035 8233532 5338658 5195819 3823293 5406804 0 4847013 4974070 21014718 9306381 0 9340671 8646422 5939189 0 0 9526272 7279294 113533 7181992 8046292 11518071 12649254 6818143 4229925 5341427 0 0 157149 5492 0 238211 0 0 7132 0 0 0 3146851 0 3888 0 0 0 0 17775 206107 48640 0 309399 0 0 0 0 4753 91268 0 0 5321 72900 12595 0 58843 5274 +AAIDAQK MGYG000000233_02449 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066785|m__MGYG000000233 1.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,36DUZ@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 E 1.0 Aminotransferase 1.0 - 1.0 - 1.0 - 1.0 ko:K10907 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 ABC_tran,Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02449 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K10907:K10907; aminotransferase [EC:2.6.1.-] 1.0 none 1.0 243287 0 0 0 0 0 131604 0 0 283463 0 0 0 330119 0 0 0 0 142384 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194748 0 329124 0 0 0 0 0 518497 0 0 899254 0 0 0 305123 0 0 249988 0 660198 0 0 0 0 0 0 218118 0 0 0 0 0 0 0 0 0 0 351155 0 312293 0 0 0 0 0 164217 0 0 121829 0 0 0 89082 0 0 193404 0 84814 0 0 0 0 0 0 233359 0 0 0 0 0 0 0 0 0 0 78784 0 0 0 0 0 0 0 426733 0 0 150718 0 0 0 0 0 0 0 0 223784 0 0 0 0 0 0 53837 0 0 0 0 0 0 0 0 0 0 145717 0 130747 0 0 0 0 0 137069 0 0 0 0 0 0 116438 0 0 81866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIDAYYDQYGVK MGYG000000262_01269 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,25V0N@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_01269 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00762:pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 388815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1133178 0 447863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378482 0 332153 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIDAYYEQYGA(Ala->Val)K MGYG000002992_01058;MGYG000002304_01630;MGYG000002528_00495;MGYG000001338_00074;MGYG000000206_02791;MGYG000001456.1_02603;MGYG000004785_01588;MGYG000000200_01565;MGYG000002445_01039;MGYG000000278_03671;MGYG000002216_02002;MGYG000000184_02212;MGYG000001714_02809;MGYG000002756_01770;MGYG000000028_01453 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 0.4 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002992_01058 0.06666666666666667 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00762:pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 859049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 777310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIDAYYEQYGAK MGYG000002992_01058;MGYG000002304_01630;MGYG000002528_00495;MGYG000001338_00074;MGYG000000206_02791;MGYG000001456.1_02603;MGYG000004785_01588;MGYG000000200_01565;MGYG000002445_01039;MGYG000000278_03671;MGYG000002216_02002;MGYG000000184_02212;MGYG000001714_02809;MGYG000002756_01770;MGYG000000028_01453 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 0.4 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002992_01058 0.06666666666666667 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00762:pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] 1.0 none 1.0 1159014 1378935 1558836 0 0 907595 626350 1300083 0 0 1625553 1217191 1409584 0 1378734 1173843 888614 968783 721884 1278816 1027546 858088 699678 617334 1177002 888434 856849 933499 943994 1063702 630943 1418897 1128745 1099341 0 634367 516689 1097676 0 3452571 621284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1237081 0 0 0 0 1644619 0 320052 4078620 0 0 0 0 0 0 0 1131897 2390855 988436 0 0 823096 793959 1049829 0 0 624809 1041071 1054881 0 950830 1023009 1013041 735501 857726 1060131 906083 1307618 937474 725261 993121 1075166 1174571 1171825 1080383 1062509 969796 1419472 1076299 1476046 0 831368 1050712 817371 0 2422766 1172067 0 0 0 685876 0 0 0 916022 958577 531310 0 0 1317164 750225 0 0 187287 0 699264 0 474221 0 0 540266 879415 796527 843003 2368098 0 1257696 0 0 0 0 1807457 0 1998878 1537587 0 0 0 1101586 633648 0 0 1094919 865361 1114106 0 0 582420 0 633474 539086 0 1168173 805097 856546 0 0 0 928859 889529 1115795 0 1584586 0 2206467 0 0 0 0 1385188 +AAIDAYYEQYGAKH MGYG000002528_00495;MGYG000000028_01453 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,3WGS1@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00495 0.5 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00762:pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] 1.0 none 1.0 0 211698 0 0 0 143582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139369 0 183844 0 0 0 0 0 0 0 85492 0 0 0 0 0 0 0 440854 0 0 0 209670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196491 0 369510 0 0 0 0 0 0 0 208138 0 0 0 0 0 0 0 1371135 0 0 0 767101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1538741 0 553082 0 0 0 0 0 0 0 1335497 0 0 0 0 0 0 0 169267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIDAYYEQYGVK MGYG000001086_00030;MGYG000000233_02103;MGYG000000205_02528;MGYG000001199_01180;MGYG000002290_03136 domain d__Bacteria 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 0.6 186801|Clostridia 0.8 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001086_00030 0.2 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00762:pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] 1.0 none 1.0 1043880 233045 0 823909 506087 326521 1334873 1065587 1219945 1125781 0 645764 0 762690 0 0 0 0 927815 985186 0 640831 0 515394 850003 909145 0 0 0 0 0 380851 0 1321165 0 898704 681212 356589 1414315 903821 804549 1777463 1012578 661791 1420742 1481150 1089598 1913338 1202874 1920541 0 1452198 1385429 0 0 0 1212632 1451847 0 820287 0 621872 1345164 1185708 0 0 0 0 0 1056858 896607 1408729 0 1319421 1050681 683212 385328 0 434167 0 0 0 0 580344 559186 562505 0 0 0 0 489395 0 0 0 0 312699 0 0 0 0 721028 589326 0 0 0 0 0 0 0 623284 0 0 441354 0 1135296 544269 732542 827226 864446 896351 1136764 1131440 836569 1184902 842994 584760 0 972141 929952 0 0 0 628296 1136528 0 972388 0 625017 1063592 896324 0 0 0 0 0 864466 773273 1100600 0 1105899 775536 676160 0 0 0 0 0 281507 0 0 293480 314599 442954 0 0 0 0 0 0 0 0 347407 0 0 0 451018 0 0 0 0 0 0 0 0 177165 0 0 0 238019 266482 +AAIDDYYK MGYG000002517_00833 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00833 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00762:pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] 1.0 none 1.0 319840 0 0 0 0 0 0 0 0 0 0 0 0 253651 0 0 0 0 0 0 0 0 0 0 0 289571 480988 0 0 0 0 0 0 0 0 289474 424731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89648 0 0 0 0 0 0 0 0 0 0 0 171213 0 0 0 0 0 0 0 0 0 109018 0 0 177269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216715 0 0 0 0 0 0 0 0 0 0 0 1607714 0 0 0 0 0 0 0 0 0 0 0 0 2170086 0 0 0 0 0 0 0 0 0 0 0 1983454 1717864 0 0 0 0 0 0 0 0 1791527 2271985 0 1376396 0 0 0 0 0 0 0 0 0 0 0 0 1876084 0 0 0 0 0 0 0 0 0 0 0 1661157 2040770 0 0 0 0 0 0 0 0 2405491 1629237 0 +AAIDDYYR MGYG000000133_02579 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02579 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00762:pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] 1.0 none 1.0 222387 118396 316939 0 0 140206 233259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221998 0 123824 0 0 299662 0 0 0 445158 0 0 0 187339 350719 0 0 109080 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140224 0 0 0 0 0 0 0 0 0 0 0 0 2090655 1894354 1729844 0 0 1101280 2852877 0 0 0 1672024 0 0 3916767 1924995 0 0 0 0 0 2614548 1609532 0 1231923 0 1700592 2331075 0 2827894 0 0 0 2941077 1922849 1363932 0 1476245 1311574 +AAIDEYYK MGYG000002492_02249 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_02249 1.0 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00762:pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252316 0 0 0 0 184305 0 0 0 0 120518 0 0 0 0 200866 0 0 0 0 0 0 0 276999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1401455 0 0 0 0 907778 0 0 0 0 1458084 0 0 0 0 340866 0 0 0 0 481840 0 0 1128431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633598 0 0 0 0 1069192 0 0 0 0 1132314 0 0 0 0 1540085 0 0 0 0 1328428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 173280 0 0 0 0 206943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184673 0 0 0 0 119752 0 0 0 0 391393 0 0 0 0 0 0 0 0 0 0 +AAIDHNIPLITNAR MGYG000001489_01217;MGYG000002438_01117;MGYG000003521_01059 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia,22X6E@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 EF 1.0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001489_01217 0.3333333333333333 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01955:carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 244983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398174 0 0 0 0 156784 0 0 0 0 315585 0 510891 0 0 0 0 0 0 0 0 +AAIDLEKDSAELKAELENATGQK MGYG000002492_00340 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000002492_00340 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2007604 0 0 0 0 0 0 0 0 0 1052733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376731 0 0 0 0 0 0 0 0 0 612608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1196610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIDLFGIADK MGYG000002506_02523 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0126@1|root,KOG1367@2759|Eukaryota,37R6T@33090|Viridiplantae,3GA5G@35493|Streptophyta,4JDX3@91835|fabids 1.0 2759|Eukaryota 1.0 G 1.0 Belongs to the phosphoglycerate kinase family 1.0 - 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N,MS_channel,PGK,TM_helix,Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02523 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 94921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378330 0 0 0 0 255592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416732 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIDLSADKVTR MGYG000003266_01673;MGYG000001636_00165;MGYG000002050_01400 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1544@1|root,COG1544@2|Bacteria,2GMYF@201174|Actinobacteria,4CVME@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003266_01673 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K05808:hpf; ribosome hibernation promoting factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 753134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIDNSFNVLR MGYG000003992_00508 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__43-108|s__43-108 sp001915545|m__MGYG000003992 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003992_00508 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03072:secD; preprotein translocase subunit SecD|K12257:secDF; SecD/SecF fusion protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2811730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIDNSYNVLR MGYG000002935_00389;MGYG000000243_01847;MGYG000002478_01470 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,4NE1X@976|Bacteroidetes,2FMPX@200643|Bacteroidia,4AMC3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA 1.0 secD 1.0 - 1.0 - 1.0 ko:K03072,ko:K12257 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 2.A.6.4,3.A.5.2,3.A.5.7 1.0 - 1.0 - 1.0 SecD_SecF,Sec_GG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002935_00389 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03072:secD; preprotein translocase subunit SecD|K12257:secDF; SecD/SecF fusion protein 1.0 none 1.0 3719423 3844850 8496644 4800101 7087359 4216831 4210172 3732747 3863857 3060951 3409161 5113317 7135112 3973395 3680258 6622385 4711156 3233369 3206662 3666729 4472593 3766383 1087682 5391493 3617263 5217826 4122965 3518976 4357652 3761267 8802384 5118806 9236493 3217356 3778220 4405834 3689739 9763129 2433374 1678497 2727467 2720078 3800573 2055294 1981447 2441308 2497567 2525792 2504416 2426724 6035455 2249857 2666510 3958515 2185938 1846227 2286894 2461057 2122289 2182327 2579692 1667390 2019742 2717801 2551022 2234148 2392523 2182310 1978013 2443720 2804867 2041057 2247623 2460874 2656884 2292365 1744651 1299798 2166101 2043586 3796616 2655001 2626074 1435106 2683532 1861010 2015980 2675917 4393698 2595726 2360489 3191771 1983623 3281567 1697317 1739585 1746285 1326049 2809228 2368354 2014924 1945454 1650114 2728317 2272842 1786500 3065975 1454204 1534456 1348634 1860631 2366145 2369824 2004076 533067 949930 781949 0 711017 427577 408006 0 376773 0 147610 569603 0 0 1177954 0 1050265 558904 0 0 0 326460 0 532733 623783 374125 0 921994 0 0 401852 431270 516112 0 380962 0 0 904054 2370688 1434728 625434 1906418 4618879 2242870 0 2350760 2190454 701141 1401142 1824251 5739766 1328268 1450319 3228456 1886080 3806515 1884590 2614373 1319637 2229020 3700462 3069086 1716185 1894495 1495108 3402421 2050480 2364309 2288413 1709880 1030551 2046645 2664495 1732122 2481079 2065146 +AAIDSGVC(Carbamidomethyl)VVAEEDGVIENVQSDKIVVKAK MGYG000003149_00719 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA4285|s__UBA4285 sp900542465|m__MGYG000003149 1.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,25V1J@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 - 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003149_00719 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03043:rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133650 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390527 0 734781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433000 0 1726979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIDSGWLSADHQVGQTGK MGYG000002287_00701;MGYG000002287_01182 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Butyricicoccaceae|g__Agathobaculum|s__Agathobaculum sp003481705|m__MGYG000002287 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,36DD9@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002287_00701 0.5 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1209396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIDSLGASD(Cation_Na)DAAAEDTDAK MGYG000001338_01847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,NAD_binding_7,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01847 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 979504 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIDSLGASDDAAAEDTDAK MGYG000001338_01847 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Psort location Cytoplasmic, score 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,NAD_binding_7,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01847 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 1058225 3737387 1318763 981136 2349883 1014437 618632 1280685 0 1593389 2524518 1200598 1084131 840834 1865570 1260764 0 2396306 0 1180493 0 987598 1914993 702503 1538100 914746 1054124 2586921 429362 1083608 1381912 3804767 1044763 938734 0 914391 688685 1371760 884437 6341591 598522 710210 977256 578397 973244 1104327 0 482661 1030053 577028 463428 503294 672505 178121 0 7347785 0 853843 0 0 3325442 1081990 455125 651466 868214 5754120 920273 666321 6167629 2535459 0 1044302 0 545192 433053 358208 1370308 7217665 1325487 1115995 571408 689808 891012 1083402 0 807337 845719 1873572 906141 836851 1166143 892345 0 928823 0 964152 0 1368425 1110734 490622 1103261 1037183 1215752 1173803 640239 1804510 1767273 7136822 1953613 1276632 0 0 809548 1450541 771907 10028342 1206690 900051 2469696 842488 953062 743807 0 1141151 1781571 922194 1130213 1109798 0 1256435 0 1832454 0 453495 0 1141767 419787 1204083 0 477879 871506 1936933 730175 834806 6562928 4054022 1303397 0 0 619492 356629 1717739 839328 13977823 3540648 864878 1255205 849184 1416204 1073003 0 688448 1482185 1333305 1617330 1406794 967264 2150712 0 2022217 0 578432 0 1070245 4923774 1818534 1115492 793350 894895 4813832 933131 916103 6307152 9305236 8715415 1077592 0 988478 921247 3567843 +AAIDSLGTDAEATTDDADAEATDDTAADDTAETTEEAAE MGYG000000171_00799 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 1.0 186801|Clostridia 1.0 M 1.0 Cobalt chelatase (CbiK) 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_00799 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1944077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIDSLGTEAATEDEAAEAETAEAETEAAEE MGYG000000133_00237 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3Y16Z@572511|Blautia 1.0 186801|Clostridia 1.0 M 1.0 Cobalt chelatase (CbiK) 1.0 cbiK 1.0 - 1.0 4.99.1.3 1.0 ko:K02190 1.0 ko00860,ko01100,map00860,map01100 1.0 - 1.0 R05807 1.0 RC01012 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 CbiK,TP_methylase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00237 1.0 sirohydrochlorin cobaltochelatase. cobaltochelatase. This enzyme, which forms part of the anaerobic (early cobalt insertion) cobalamin biosynthesis pathway, is a type II chelatase.-!-It is ATP-independent and exists as either a monomer (CbiX) or a homodimer (CibK).-!-CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2.-!-The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding.-!-CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2.-!-See EC 6.6.1.2 for the cobaltochelatase that participates in the aerobic cobalamin biosynthesis pathway. (1) Co-sirohydrochlorin + 2 H(+) = Co(2+) + sirohydrochlorin. (2) Co-precorrin-2 + 3 H(+) = Co(2+) + precorrin-2. 1.0 1.0 1.0 1.0 Porphyrin metabolism|Metabolic pathways 1.0 K02190:cbiK; sirohydrochlorin cobaltochelatase [EC:4.99.1.3] 1.0 none 1.0 0 232331 199790 0 224846 118784 111008 0 255206 0 0 0 0 0 0 0 0 0 0 0 0 96066 0 202606 0 0 0 0 0 0 0 221037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162043 0 184964 0 0 339875 0 0 0 193669 0 0 0 0 258540 0 0 0 0 0 0 0 0 0 397066 217676 0 0 257619 0 0 204145 179815 0 0 0 176544 0 50146866 50782004 50725594 71978729 5485583 32011924 63564190 0 43225411 94894886 0 0 0 0 69144479 0 83198303 0 0 0 0 64425109 0 43421473 92948245 27877691 81161139 0 76895601 0 0 96309191 175436804 0 0 0 101277954 17947143 +AAIDSTDAENMSDADVDKIK MGYG000000018_01360 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus|s__Coprococcus eutactus|m__MGYG000000018 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000018_01360 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 975513 0 0 0 0 1084712 0 0 0 0 1267409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192038 0 0 0 0 0 0 0 0 0 563256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEAAGGKIEE MGYG000002506_02942;MGYG000002494_02450;MGYG000002515_03184;MGYG000002323_00405;MGYG000002366_00455;MGYG000002534_00411;MGYG000002535_04680;MGYG000002477_00168 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,3XPK7@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02942 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 3844799 3098485 3560775 2946774 2659633 5088603 4797686 4017637 3303904 4119090 3012006 2878460 2216551 4635533 2909155 2050521 3464964 0 3309368 3402298 4001667 4303639 0 7219235 4242979 4369307 4230152 0 4284681 4506950 3563333 3906332 3471305 0 4945461 3351968 3660881 3295667 8662406 8325992 8290125 6590211 6917722 15947003 7969561 8218993 9036650 10805916 3223089 6545578 3914349 8452059 7783434 5938759 9363486 0 8249478 6432926 9789327 17750167 0 12698911 10246048 7194236 6929169 0 11964607 9542128 3964632 5897493 8485397 6625609 7294107 6803822 7662577 9048630 4037929 2867990 4623069 3197008 4681564 7558232 4092513 4466535 4007540 4916615 3290641 2806962 3928464 3671222 3036617 3826625 3682451 0 3060986 3529449 3904649 6774246 0 7382901 4329176 3904551 3149146 0 3181307 3520862 3700804 3076933 3418965 4564490 2546748 3846722 2638414 3295202 5574170 5452338 5071127 4358038 4276324 6295092 6770286 7020447 4080348 7843447 4073875 5317974 6355033 5050873 5306423 4974418 4626526 0 4711696 4770582 6259278 6930627 0 5054681 6250268 5311684 4938519 0 4391510 5598116 3382659 4922483 5124772 9945444 8137067 7489515 4383501 3743630 0 286184 187061 0 0 0 0 170401 0 0 0 0 278651 0 0 145934 0 0 0 0 0 0 0 206867 0 106139 0 0 326465 1014524 0 0 0 0 0 0 0 0 +AAIEADRYLQQL MGYG000002960_00851;MGYG000003697_02811 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002960_00851 0.5 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 K00384:trxB, TRR; thioredoxin reductase (NADPH) [EC:1.8.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 415148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 658721 0 482541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEAER MGYG000002478_04055;MGYG000003351_01292;MGYG000001306_03156;MGYG000002218_02990;MGYG000002438_02820;MGYG000001346_01037;MGYG000002549_00642;MGYG000000224_00060;MGYG000000098_03753;MGYG000004797_00961;MGYG000003701_01280;MGYG000000105_01246 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia,4AM3W@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 C 1.0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_04055 0.08333333333333333 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 K00384:trxB, TRR; thioredoxin reductase (NADPH) [EC:1.8.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1629760 0 0 0 0 0 0 0 0 1673394 0 0 0 0 0 0 0 0 0 0 0 1770318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2415208 0 0 0 2687486 0 0 0 0 0 0 3390882 0 0 2551841 0 3744487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1041901 0 0 0 0 0 0 0 1160340 0 0 0 0 1315263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 725544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1824909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2133878 0 1366271 0 0 1370236 1720544 0 0 0 0 0 0 +AAIEAGANDFIQKPLNAEQIHHIISSR MGYG000002517_01575 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG4753@1|root,COG4753@2|Bacteria,1VAG0@1239|Firmicutes,24P6B@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 cheY-homologous receiver domain 1.0 - 1.0 - 1.0 - 1.0 ko:K03413 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 HTH_18,Response_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01575 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03413:cheY; two-component system, chemotaxis family, chemotaxis protein CheY 1.0 none 1.0 0 0 0 0 0 314271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163694 0 170004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243328 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208552 0 246326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 556751 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364536 0 483635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEAGC(Carbamidomethyl)R MGYG000000016_00642;MGYG000000177_00366 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum 1.0 COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,36EW0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 pyruvate flavodoxin ferredoxin oxidoreductase domain protein 1.0 vorB 1.0 - 1.0 1.2.7.11,1.2.7.3 1.0 ko:K00174 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00009,M00011,M00173,M00620 1.0 R01196,R01197 1.0 RC00004,RC02742,RC02833 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFOR_II,POR_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000016_00642 0.5 2-oxoacid oxidoreductase (ferredoxin). | 2-oxoglutarate synthase. OFOR. | KGOR. This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For example, see EC 1.2.7.3 and EC 1.2.7.7. | Highly specific for 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.1 and EC 1.2.7.7.-!-Formerly EC 1.2.7.9. a 2-oxocarboxylate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = an acyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. | 2-oxoglutarate + CoA + 2 oxidized [2Fe-2S]-[ferredoxin] = CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin] + succinyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00174:korA, oorA, oforA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11] 1.0 none 1.0 0 0 0 2621906 0 1866226 0 0 2339495 0 0 0 0 0 0 0 2043844 0 3295288 2204768 3429675 3214612 0 2048199 3181270 0 2182657 0 1671360 2890754 0 0 0 0 2661785 0 0 0 0 0 0 637815 0 694891 0 0 681022 0 0 0 0 0 0 0 584781 0 593861 173864 351745 843384 0 744075 468150 0 286737 0 533540 562736 0 0 0 0 436870 0 0 0 0 0 0 1122260 0 1586514 0 0 1912550 0 0 0 0 0 0 0 655837 0 3476725 4149633 1316856 2339159 0 2218993 2057022 0 2547135 0 2295443 2211262 0 0 0 0 1989083 0 0 0 0 0 0 105107 0 250182 0 0 294570 0 0 0 0 0 0 0 248079 0 1193315 571656 119516 536784 0 643983 302964 0 168821 0 526950 163017 0 0 0 0 603874 0 0 0 0 0 0 1228957 0 137166 0 0 756039 0 0 0 0 0 0 0 552188 0 345366 355537 606019 431444 0 286131 1096861 0 1197571 0 895194 315852 0 0 0 0 1117410 0 0 0 +AAIEAGISVYNR MGYG000004296_01202;MGYG000004733_01556 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia 0.5 186801|Clostridia 1.0 E 1.0 methionine synthase I, cobalamin-binding domain 0.5 acsE 1.0 - 1.0 2.1.1.258 1.0 ko:K15023 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R02289,R10243 1.0 RC00004,RC00113,RC01144,RC02871,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pterin_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004296_01202 0.5 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the N(5) group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein.-!-Involved, together with EC 1.2.7.4 and EC 2.3.1.169, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea. (6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein] = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K15023:acsE; 5-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase [EC:2.1.1.258] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2018584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEAGK MGYG000000262_02231;MGYG000001300_02035;MGYG000000205_00404;MGYG000001065_00276 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,21Z3N@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 E 0.5 BMC 0.5 pduB 0.5 - 1.0 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 0.5 - 1.0 - 1.0 - 1.0 BMC 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02231 0.25 - - - - 0.5 0.5 0.5 0.5 - 0.5 - 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEAGNEDAK MGYG000004733_01879 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900548245|m__MGYG000004733 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_01879 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 614300 0 1498465 0 0 1549406 0 0 0 0 0 0 0 769494 1187349 0 0 2123544 0 0 1056607 2139050 1496182 1090891 0 632941 0 1489666 0 0 973481 0 1424031 0 0 0 748936 1621371 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 941721 0 326211 0 0 1097895 0 0 0 0 0 0 0 1154065 1646873 0 0 338716 0 0 846437 2047659 668542 823333 0 1727529 0 901128 0 0 1125068 0 873473 0 0 0 872072 427639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390557 0 0 173295 0 0 0 0 0 0 0 270967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488547 0 932095 0 0 0 0 323883 +AAIEALPAK MGYG000000098_01032;MGYG000002560_00984;MGYG000002455_00337;MGYG000004797_02626;MGYG000000243_02802 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 2E3DE@1|root,32YCK@2|Bacteria,4NVFG@976|Bacteroidetes,2FT26@200643|Bacteroidia,4ARB3@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 S 1.0 Stress responsive A B barrel domain protein 0.8 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Dabb 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000098_01032 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1767385 1760937 2253802 0 2524243 2167723 1853647 1443430 0 0 1757913 1570702 2341242 0 0 2825606 0 2022764 0 0 0 2011660 1774575 2409729 1641738 1857537 1783926 1962095 1655585 0 0 0 2392308 0 1698348 1752706 1998312 2895264 1459879 1230164 1294896 0 1418633 1436880 1654322 1436187 0 0 2614958 1657196 2382505 0 0 1722310 0 1180826 0 0 0 1260464 1385553 1732939 1672649 1622369 1417702 1169787 1764524 0 0 0 1521368 0 1931656 1676327 1548654 1569240 1454728 1299870 1775265 0 1842516 1438347 1493138 1288173 0 0 1433365 1015506 1572681 0 0 1681940 0 2499553 0 0 0 1339725 1963820 1529483 1780876 1119847 1403108 2046986 1256816 0 0 0 1155629 0 1628430 1428137 1382141 1369955 1185101 1016903 1221001 0 1122662 1185543 1572883 841504 0 0 11801085 1448360 4528110 0 0 0 0 713323 0 0 0 1559067 505216 1569603 902515 959738 1333225 1187582 1755589 0 0 0 1057510 0 1131096 1266488 1206620 1325293 1354566 998026 1265625 0 1932064 1484952 1413924 1739490 0 0 1748471 1291310 1252250 0 0 1227860 0 3191571 0 0 0 1350030 2841350 1095614 1347706 1953295 1049850 2204603 1354445 0 0 0 910868 0 1096447 1126407 209847 1166787 +AAIEAVK MGYG000000196_00058;MGYG000002033_00995;MGYG000002549_03488 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1454@1|root,COG1454@2|Bacteria,4NIU1@976|Bacteroidetes,2FMAN@200643|Bacteroidia,4AKAE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 fucO 1.0 - 1.0 1.1.1.77 1.0 ko:K00048 1.0 ko00630,ko00640,ko01120,map00630,map00640,map01120 1.0 - 1.0 R01781,R02257 1.0 RC00087,RC00099 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00058 0.3333333333333333 lactaldehyde reductase. propanediol oxidoreductase. - (1) (R)-propane-1,2-diol + NAD(+) = (R)-lactaldehyde + H(+) + NADH. (2) (S)-propane-1,2-diol + NAD(+) = (S)-lactaldehyde + H(+) + NADH. 1.0 1.0 1.0 1.0 Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Microbial metabolism in diverse environments 1.0 K00048:fucO; lactaldehyde reductase [EC:1.1.1.77] 1.0 none 1.0 0 0 0 970277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEE(Cation_Na)GIVPGGGVAYIR MGYG000004876_02137;MGYG000002478_00380;MGYG000003363_02977;MGYG000002171_01748;MGYG000004763_01826;MGYG000002470_00024;MGYG000000243_00634;MGYG000002455_00111;MGYG000001346_02504;MGYG000002933_01569 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004876_02137 0.1 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEEGIIPGGGVAYIR MGYG000001433_02375;MGYG000001345_00379;MGYG000002281_01780;MGYG000002549_02837;MGYG000000013_01093;MGYG000003351_04147;MGYG000000196_04163;MGYG000001659_02186;MGYG000003252_04996;MGYG000003922_03103;MGYG000002275_02480;MGYG000000029_01790;MGYG000001378_04618 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 0.8461538461538461 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000001433_02375 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 4334899 4468299 3748537 5067697 3960971 3408217 7774027 6094129 6125975 6704547 9011093 4486045 3108029 4731522 4211847 4238475 5286877 0 4111242 4244864 4760624 2986059 7512123 5035975 4342413 5079658 4786881 5461922 5587225 5770025 6292727 5784232 3571616 5996763 4691598 5798802 5617474 2940432 1959349 1779257 2132593 2582538 2625421 2968169 2060255 2221748 1995399 3124535 6410403 2360663 2372317 2639130 3462169 2375245 2902615 1169052 2278943 2095639 2241892 3550485 1920265 2955477 2780541 0 2448991 1376424 2480611 2318623 1922412 3580911 2012861 2086724 2352656 1735750 2305381 2196332 1683632 1468817 2803975 1528692 2575451 2540121 1953648 1500501 2424365 1354547 2723331 1507292 1411917 1327705 1494747 1555011 2145850 3080637 1269464 1243583 1280526 1484463 2480982 2480648 1591543 1843758 1588154 1590340 1671228 1737189 1665103 1356397 1959230 1353433 1670438 2195553 1554852 2742232 1912937 1936634 2074853 1761285 2295112 2837539 2206297 2531994 2102697 2547430 3371987 2176375 2732033 1952905 2105422 2363600 1850171 6831373 2058639 1685473 2271728 0 9703114 2617546 2524276 2984223 2388901 6960990 2204320 2256900 2194125 2205465 2518623 2400891 2338535 2476349 2579444 2300169 1022498 1108451 880887 1655193 1322440 1963211 1227312 1182477 1569597 1088663 2631545 803624 2050862 658254 980116 1109290 1378935 975096 831303 1451890 833307 1232493 799444 1515972 1217015 1552550 885156 901587 934845 1450256 1137454 1732641 578346 1323677 1383227 1351129 2493723 1340211 +AAIEEGIVAGGGTTYIR MGYG000002834_01380;MGYG000001056_01919;MGYG000003697_01689;MGYG000002293_01257;MGYG000001770_01876 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002834_01380 0.2 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 130495 212514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196037 0 0 0 0 0 0 0 0 237807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1384085 1404440 2474687 986783 1374408 2118802 1348679 0 0 0 2706752 0 0 0 0 1446056 0 5408568 0 0 0 2170599 9456250 2406795 1037984 1390476 0 4998821 1123746 0 1209372 1438147 1880994 1644896 0 1282190 1239032 2042071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79244 0 0 0 0 +AAIEEGIVPGGGVAYIR MGYG000004876_02137;MGYG000002478_00380;MGYG000003363_02977;MGYG000002171_01748;MGYG000004763_01826;MGYG000002470_00024;MGYG000000243_00634;MGYG000002455_00111;MGYG000001346_02504;MGYG000002933_01569 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004876_02137 0.1 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 15219614 16720469 25156426 20943299 21378969 15279702 19609392 17674046 17532708 18822133 20790467 18553768 23508013 14819157 12964666 20922494 22700086 20413386 16594090 13944760 14204038 12324109 24909334 18483895 13609123 0 18029280 27800895 16107245 19097755 28343248 19674541 21725838 13272326 16257768 17308623 14453302 21683981 0 0 7601388 8185981 11682133 8546449 5835361 8391295 7141163 9141513 10681095 8641613 17247700 7948635 8098470 12794013 11958444 0 7198975 7978935 8015456 9012973 14753966 6692225 7874722 7338912 8726791 0 8633999 7944165 8140288 10558933 9815543 6739491 6689575 5993155 7032266 0 7909972 6612142 9203912 7665063 15301624 10785218 9761803 7623076 10579461 8634254 13405869 11131598 14045251 8531865 6943463 10527110 9807575 20930856 7614935 6818584 6818195 6800915 18326095 9934417 7501654 9174360 7210767 13287820 7674339 6709961 13309449 6718446 6998724 6366537 9039179 10977446 9701214 9332862 2307137 2109483 2349332 2447973 2195647 0 2213198 2982927 0 3239589 3936612 2720369 2840650 2267690 2279960 2695359 1979383 0 2932462 1599517 0 1887594 2208034 0 2585295 2281238 2988961 2348221 2079564 2499638 1958707 2233252 0 2595955 3455755 2585085 2186408 1854187 3911090 3517464 3646368 4587311 7650006 5590155 3955856 4389105 4207375 2560375 9968856 3557164 10611974 3289360 3692122 6868811 4039017 10594012 3619210 5006756 2795507 4115982 10704213 4761321 5182064 6004519 3774815 9437338 3998194 5099723 4886536 5321992 3897123 4968072 5000350 4091630 5287377 4425304 +AAIEEGIVPGGGVT(Thr->Ala)YIR MGYG000001787_00205;MGYG000001306_00685;MGYG000001364_01313;MGYG000000236_02963;MGYG000001789_02329;MGYG000003693_01240 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000001787_00205 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3961644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEEGIVPGGGVTYIR MGYG000001787_00205;MGYG000001306_00685;MGYG000001364_01313;MGYG000000236_02963;MGYG000001789_02329;MGYG000003693_01240 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000001787_00205 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 96121 0 0 0 163976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 130795 0 214880 0 0 194684 1208929 509207 1237232 1641279 0 1252218 0 1886580 1579298 2376846 2194480 1427699 1156965 1724891 1925920 0 1626441 12846077 1104539 1059009 0 1268119 21768139 865591 1548726 1947703 1775577 14939965 1458715 0 1067069 1364446 1145456 1442282 1536815 1299492 1701195 1073386 0 0 0 0 0 0 0 0 137652 0 0 0 116111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316602 0 0 201222 0 0 0 0 0 0 0 0 348957 0 0 0 0 0 0 0 0 0 0 0 497219 0 0 3161542 0 0 0 0 3227084 0 0 616607 116569 2861633 0 0 513408 0 0 714394 241817 0 0 0 0 0 989497 0 0 1039170 0 0 0 168969 0 0 0 0 172503 0 0 0 0 0 0 0 0 359217 0 0 0 0 0 0 0 0 153838 0 0 0 0 842106 +AAIEEGLLPGGGVALVQAAAK MGYG000003683_00853;MGYG000000756_00212;MGYG000003730_00164;MGYG000001292_00715 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CZJK@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016020,GO:0016465,GO:0022610,GO:0030112,GO:0030312,GO:0030313,GO:0031975,GO:0032991,GO:0036293,GO:0040007,GO:0042026,GO:0042603,GO:0043388,GO:0044093,GO:0044183,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051704,GO:0061077,GO:0065007,GO:0065009,GO:0070482,GO:0071944,GO:0101031,GO:1990220,GO:2000677,GO:2000679 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003683_00853 0.25 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 130408 0 455225 0 183097 0 0 0 0 281946 208080 0 571970 0 0 681639 0 126882 0 0 0 0 0 0 98763 94134 0 191747 172233 0 0 0 0 0 0 0 0 270629 713872 862356 793460 993269 901761 1322411 914131 771639 0 688421 646947 0 2371683 540647 0 1023893 0 4744848 0 688282 0 773276 1654687 2446724 1337975 592978 866717 3338174 1126397 0 1690428 0 920180 0 0 861736 1109334 5706378 1397376 1468762 0 168788 0 162702 257751 971052 0 0 0 0 709580 0 0 1761975 0 0 0 1095532 0 1274703 0 170915 285032 0 0 1010113 0 0 0 0 3214890 0 0 0 0 187422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151898 0 0 0 0 0 0 150173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 501677 0 0 0 64679 0 0 0 0 0 274231 0 0 0 0 0 0 0 30905 156382 0 0 368265 75885 0 0 0 0 0 0 0 0 0 0 0 +AAIEEGTVPGGGVAYI(Xle->Tyr)R MGYG000003521_02097;MGYG000000355_02196;MGYG000003251_00039;MGYG000002218_01379;MGYG000000044_03505;MGYG000002033_00862;MGYG000002438_00745;MGYG000000174_04760;MGYG000000138_02067;MGYG000001489_00629;MGYG000003338_01836 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22WR5@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003521_02097 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEEGTVPGGGVAYIR MGYG000003521_02097;MGYG000000355_02196;MGYG000003251_00039;MGYG000002218_01379;MGYG000000044_03505;MGYG000002033_00862;MGYG000002438_00745;MGYG000000174_04760;MGYG000000138_02067;MGYG000001489_00629;MGYG000003338_01836 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,22WR5@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003521_02097 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 705679 736810 608208 913729 737917 681287 995857 1041621 715134 736904 0 991095 584185 690802 630600 810707 943198 762856 684769 880000 846625 581897 1016734 897147 634602 762626 952357 722697 598516 1026894 1106683 1008026 772317 953475 511543 954307 641794 540077 844868 1012828 1002363 721907 1269523 976360 828534 1177093 755939 1291278 0 2697053 1047428 942229 903690 1364109 1347848 740391 826540 802719 4035618 1133976 805873 1058799 942009 1026544 1061547 741890 1250636 2352484 760391 2389575 1028079 899192 898073 909626 1018024 907948 1122929 1668183 1531934 919866 2232029 1773947 1585042 1246812 1568546 1522229 0 0 1548959 1212733 1212181 1322127 1781211 1790756 1289468 977712 3374818 1101915 0 1513817 1288697 1690812 1240822 1873539 1278874 2327705 0 1920941 1143183 887441 1272428 1552766 1630700 1338533 1438754 2302891 1613800 1140925 2080553 1508886 1545444 1476414 1274828 1528994 0 2348959 2000934 1220787 1382478 1810893 1430403 1481235 1500680 919597 5539800 1384013 2132250 1538258 1622988 1506545 1249784 1480745 1546814 2816812 2041185 3109548 1587003 2033664 1521098 1678589 1293257 1260875 1999245 2547196 2182933 2641915 3665154 2745866 2183902 2160153 2237050 2703540 0 5599430 4554121 1761178 1639334 3085816 2529986 3692320 1754575 2258840 8103367 1834607 3300361 2073976 2425508 2073760 1980187 3036743 2422049 7517469 2268812 5772572 1708341 2463945 2320452 2315293 2621012 2295517 +AAIEESK MGYG000000077_00225;MGYG000002517_01578 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,25WFS@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 E 0.5 Periplasmic binding protein 0.5 braC 0.5 - 1.0 - 1.0 ko:K01999 0.5 ko02010,ko02024,map02010,map02024 0.5 M00237 0.5 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 0.5 3.A.1.4 0.5 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_00225 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 0.5 K01999:livK; branched-chain amino acid transport system substrate-binding protein 0.5 none 1.0 0 0 0 0 0 0 0 0 153569 186509 0 0 0 0 208664 0 0 0 0 0 99431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54427 428508 0 0 0 0 204510 0 463714 0 0 0 108862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290425 269335 0 0 0 0 119602 0 0 0 0 0 515251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199048 0 0 0 0 244626 0 658579 0 0 0 1429499 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEFLR MGYG000002279_01754;MGYG000001319_00092;MGYG000000067_01247;MGYG000003355_01546;MGYG000000154_01998;MGYG000004735_01120;MGYG000003012_00855;MGYG000002966_02852;MGYG000000164_02267;MGYG000000404_01946;MGYG000000287_02964;MGYG000000806_00684;MGYG000002025_01407;MGYG000000133_02455 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3XYYG@572511|Blautia 0.2857142857142857 186801|Clostridia 1.0 G 0.8571428571428571 Belongs to the GPI family 0.5 pgi 0.8571428571428571 - 1.0 5.3.1.9 0.8571428571428571 ko:K01810 0.8571428571428571 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 0.8571428571428571 M00001,M00004,M00114 0.8571428571428571 R02739,R02740,R03321 0.8571428571428571 RC00376,RC00563 0.8571428571428571 ko00000,ko00001,ko00002,ko01000,ko04147 0.8571428571428571 - 1.0 - 1.0 - 1.0 PGI 0.8571428571428571 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_01754 0.07142857142857142 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 0.8571428571428571 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 0.8571428571428571 none 1.0 0 0 0 0 0 0 764660 0 0 0 0 0 0 0 600674 406388 0 2011364 0 628567 0 0 2570631 0 0 0 0 1954669 0 0 0 0 0 0 1083160 0 0 0 0 0 0 0 0 0 0 0 0 0 123525 0 0 0 0 0 0 241943 0 0 172499 0 503043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100268 0 0 0 0 105551 0 0 0 149592 0 0 0 113340 113264 0 0 0 86072 0 0 232220 0 0 0 0 341977 0 0 0 328246 0 0 110684 0 0 133505 0 332140 123161 264967 0 0 239329 0 0 0 325247 0 0 0 99805 327139 0 116450 0 113069 251360 0 488507 0 0 0 0 461103 0 0 0 272914 249101 0 112885 92260 0 194796 0 2547187 2904245 4481125 0 0 2824461 0 0 0 2134848 0 0 0 0 2149336 0 295002 0 400528 2401479 0 686536 0 0 0 0 780879 0 0 0 2796594 4218761 0 1459502 2325495 0 1962378 +AAIEGAVAK MGYG000000357_00601 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-873|s__|m__MGYG000000357 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,22VY9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000357_00601 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1352453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEGTTVEIAAK MGYG000001292_00243 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4D0P9@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplI 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02939 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L9_C,Ribosomal_L9_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001292_00243 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02939:RP-L9, MRPL9, rplI; large subunit ribosomal protein L9 1.0 none 1.0 0 0 0 0 133650 0 0 190381 0 0 0 0 271272 0 0 543477 0 381112 0 250570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 873120 0 0 935889 498631 0 799870 0 0 0 0 1920922 0 0 1318943 0 2250920 0 854149 0 203367 0 799953 0 0 761306 1084757 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217728 0 0 428054 0 0 0 0 0 288447 0 0 0 0 259256 171101 0 0 0 0 0 0 0 0 0 0 0 393525 0 0 479927 902113 0 344071 0 0 0 0 311519 0 0 654508 0 423386 0 440785 0 482167 355501 392620 0 0 345936 492502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEHGMK MGYG000000084_01029;MGYG000001627_01339;MGYG000001761_01983;MGYG000000573_01504;MGYG000004866_02019;MGYG000003921_00370;MGYG000001157_00690 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3WIYT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000084_01029 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429235 0 0 0 0 298381 0 0 0 0 378105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139078 0 0 0 0 645197 0 0 0 0 970462 0 875431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 773476 0 0 0 0 113120 0 0 0 0 907969 0 235954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1431643 0 0 800595 0 2204622 0 0 0 0 800599 0 604572 0 0 0 0 0 0 0 0 +AAIEIM(Oxidation)EADPSKFVHR MGYG000000243_01845;MGYG000002171_01133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01845 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEIM(Oxidation)EANPDKLIHR MGYG000002478_01472 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01472 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEIMEADPSK MGYG000000273_00482;MGYG000000243_01845;MGYG000002171_01133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000273_00482 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2477052 0 4385415 3002602 2978150 2099730 3738664 2439133 2925653 1991703 2096176 1986326 2343871 2114034 2023016 1841482 1998445 1548519 2147108 2195016 2417007 1943071 3033211 3789093 1862800 2714912 0 2250878 2341381 2635939 5039847 2285427 6404082 2763826 2249178 3247810 2476684 5402570 1307693 0 1291717 999249 1331531 1172082 814468 1260911 941514 952850 1226315 1084518 1889335 973029 885882 1739438 928807 830517 856386 818667 996658 757189 706525 853108 794493 936682 0 1064401 658501 999736 832299 1203222 1424310 945269 903821 1091867 948112 1308385 1387334 0 1635810 1566570 2570926 1719506 2243152 1249470 1996012 1270717 1905187 1876045 2173236 1637119 1229887 1681406 1730325 4083091 1107377 1188582 1595548 1338028 3300416 2263032 1193306 1743518 0 2262478 1974952 1735670 2167635 1091228 1265506 783164 1829649 2062003 1552412 1856280 534743 0 0 0 198194 0 0 0 401779 0 0 0 0 329737 0 0 0 0 0 0 0 0 0 539230 538179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334904 0 0 0 301349 0 230629 314298 0 348262 0 328123 224856 0 0 0 0 0 403040 0 304096 518942 0 165769 0 0 0 367123 0 0 0 0 0 287700 188848 293612 +AAIEIMEADPSKFVHR MGYG000000243_01845;MGYG000002171_01133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01845 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 1400361 4388302 0 2213016 1324185 0 0 1339033 0 0 820271 1625437 1187487 0 1173901 1488165 0 0 1060967 0 777876 0 1181337 0 0 856449 0 0 0 2800136 0 4657482 1303653 1052492 1023177 0 4080240 0 71993 91611 0 285235 116767 0 0 39710 0 0 63930 303187 81051 0 286518 54235 0 0 48619 0 176421 0 152511 0 0 50889 0 0 0 70418 0 249242 0 147924 69060 0 168806 0 735840 604087 0 707313 466105 0 0 242380 0 0 203423 818583 286410 0 719098 455662 0 0 560614 0 506512 0 573186 0 0 555663 0 0 0 371594 0 497562 443853 870809 262498 0 357829 0 110572 0 0 182433 0 0 0 179451 0 0 0 0 611460 0 0 717111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 634054 591921 0 0 0 0 0 0 0 224247 0 0 0 0 0 0 0 294315 0 0 0 0 0 0 0 0 278073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89916 +AAIEIMEADSTK MGYG000002438_03364 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03364 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 455464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1205088 0 0 0 0 0 0 0 0 1191639 0 1831269 0 0 0 0 0 0 +AAIEIMEANPDK MGYG000004797_02539;MGYG000002478_01472 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_02539 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 965137 0 445519 805055 407342 0 0 578723 764067 0 615710 756732 522633 576577 592692 811272 0 495537 566744 814664 0 0 293182 0 713583 674181 720576 411491 0 823071 0 573821 620602 0 664659 722333 573806 464471 810126 0 1378419 815100 960980 0 0 1004274 669090 0 927751 765758 2404247 746952 712404 2859504 0 722750 733617 735203 0 0 782132 0 835507 801565 907518 564709 668754 752246 0 1727689 1021740 0 962395 656749 681984 2040271 0 0 318972 0 435700 0 0 351936 0 0 0 675148 883230 0 247747 0 0 378829 0 188110 0 0 409156 0 275377 0 0 645658 512072 0 0 0 1154884 0 0 0 0 708274 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224960 0 0 0 0 0 0 0 0 0 650315 0 0 0 0 0 0 0 0 0 0 0 0 0 361811 400203 0 0 876925 0 0 0 383775 0 0 0 468705 0 1798432 0 472051 0 0 1763075 0 0 714118 325324 1638253 292727 808639 0 0 0 0 496754 371982 430667 0 +AAIEIMEANPDKLIHR MGYG000002478_01472 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0451@1|root,COG0451@2|Bacteria,4NE3U@976|Bacteroidetes,2FNS7@200643|Bacteroidia,22VZ9@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 NAD dependent epimerase dehydratase family 1.0 ltd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Epimerase,GDP_Man_Dehyd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01472 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1279933 1223710 1158439 1466448 1282170 1164341 1264800 984003 1230442 1054233 940105 1173556 1588389 1177704 969661 1725973 1412876 926927 1351639 1075631 954159 917911 1200313 1329861 960704 1159051 1228756 1005370 1163789 1122009 1840200 1396642 1393707 581535 1312879 0 1227506 1128558 502764 486469 867264 737993 1017808 850441 600536 946080 604554 637851 1055690 901544 1007015 663422 854024 1575546 708364 470124 635248 577435 832567 1088104 360461 617674 660977 693911 640833 395102 636520 712094 735789 785560 577339 409102 656463 519213 461296 740680 575234 451810 668304 584813 1077039 749650 772845 501161 427124 539516 765530 884230 747410 526016 547086 776434 534743 945993 737622 549356 559934 479471 867432 689960 424057 617855 475557 638744 620311 420831 854711 520367 494549 304270 518158 684450 501983 599099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53590 0 0 0 0 0 0 0 0 0 0 0 0 0 1020295 845556 936997 1077133 1601527 1428099 920089 1267832 1463689 639546 806740 951267 1287393 848551 1082254 1569306 1309220 1224844 1177143 1179503 765283 964509 1143998 956844 915947 1107934 1236898 1208193 1453989 1256258 1192635 1166646 542650 1204849 1261454 966488 1311453 1204270 +AAIEKKPIK MGYG000001315_02437 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,21YF6@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Pyruvate carboxylase, C-terminal domain subunit K01960 1.0 oadA 1.0 - 1.0 4.1.1.3 1.0 ko:K01571 1.0 ko00620,ko01100,map00620,map01100 1.0 - 1.0 R00217 1.0 RC00040 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.1 1.0 - 1.0 - 1.0 HMGL-like,PYC_OADA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_02437 1.0 oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). | oxaloacetate decarboxylase. | oxaloacetate decarboxylase (Na(+) extruding). oxaloacetate carboxy-lyase. | oxaloacetate beta-decarboxylase. The enzymes from the fish Gadus morhua (Atlantic cod) and the bacterium Micrococcus luteus prefer Mn(2+), while those from the bacteria Pseudomonas putida and Pseudomonas aeruginosa prefer Mg(2+).-!-Unlike EC 7.2.4.2, there is no evidence of the enzyme's involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. | The enzyme from Klebsiella aerogenes is a biotinyl protein and also decarboxylates glutaconyl-CoA and methylmalonyl-CoA.-!-The process is accompanied by the extrusion of two sodium ions from cells.-!-Some animal enzymes require Mn(2+).-!-Differs from EC 4.1.1.112 (oxaloacetate decarboxylase) for which there is no evidence for involvement in Na(+) transport.-!-Formerly EC 4.1.1.3. H(+) + oxaloacetate = CO2 + pyruvate. | H(+) + 2 Na(+)(in) + oxaloacetate = CO2 + 2 Na(+)(out) + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Metabolic pathways 1.0 K01571:oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2] 1.0 none 1.0 0 41381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEKYPNLSK MGYG000000187_00761 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,25VAF@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 ABC-type sugar transport system periplasmic component 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000187_00761 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3334382 0 0 0 0 3004521 0 0 0 0 2711551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 567966 0 0 0 0 224903 0 0 0 0 317244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516308 0 0 0 0 86717 0 0 0 0 104858 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIELMK MGYG000000089_01040 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3WHJX@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000089_01040 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 698529 0 0 0 0 0 0 0 0 0 944070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213664 0 0 0 0 130330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIENASNK MGYG000002126_00706 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__UBA1390|g__UBA1390|s__UBA1390 sp900764045|m__MGYG000002126 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,36DJ7@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002126_00706 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1605058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1779092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIENMTGLK MGYG000002528_00065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 protein conserved in bacteria 1.0 asp 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Asp23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00065 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 567758 0 0 0 398446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313815 0 146379 0 0 0 0 298013 0 0 321937 0 0 0 0 0 0 0 590009 0 0 0 313066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100947 0 432628 0 0 0 0 339474 0 0 299013 0 0 0 0 0 0 0 1283512 0 0 0 907784 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1881488 0 777185 0 0 0 0 4190352 0 0 1445837 0 0 0 0 0 0 0 259405 0 0 0 582004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 959276 0 0 0 0 1078996 0 0 300677 0 0 0 0 0 0 0 273060 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208816 0 0 172878 0 0 0 0 0 0 +AAIEPALEYLR MGYG000001315_02715 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG4134@1|root,COG4134@2|Bacteria,1TR3G@1239|Firmicutes,24A5K@186801|Clostridia,36E1C@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 S 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K02055 1.0 ko02024,map02024 1.0 M00193 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.11 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_02715 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02055:ABC.SP.S; putative spermidine/putrescine transport system substrate-binding protein 1.0 none 1.0 0 339395 1213030 0 0 0 0 570521 0 0 0 0 0 0 0 0 0 0 0 446538 0 0 0 0 0 0 0 0 0 0 0 0 663893 0 0 0 0 1016900 0 1146635 885643 0 0 0 0 998387 0 0 0 0 0 0 0 0 0 0 0 1100171 0 0 0 0 0 0 0 0 0 0 0 0 1012793 0 0 0 0 1023974 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249321 208210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 615891 0 0 0 0 0 0 0 0 0 0 0 0 598176 0 0 0 0 868145 0 222162 417280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 473543 0 0 0 0 0 0 0 0 0 0 0 0 376543 0 0 0 0 367649 +AAIETALGK MGYG000000003_01212;MGYG000001302.1_00819;MGYG000001562_02334;MGYG000001546_02855;MGYG000001420_01443 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0443@1|root,COG0443@2|Bacteria,4NERF@976|Bacteroidetes,2FMNH@200643|Bacteroidia,22UA3@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_01212 0.2 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 5527891 0 1987746 4552940 2132695 3519748 6280437 0 6587358 3338343 0 3415902 0 0 4471895 2117857 0 0 8994461 7648559 6153549 2577033 0 0 4481795 6150113 4482914 0 4293750 4717531 0 3203799 2265515 2405812 5199928 4994927 6644624 0 2028521 0 1837521 0 1510497 0 1664053 0 1887910 1733921 0 0 0 0 1761666 1520431 1904304 0 2616337 2137538 1323476 1138420 0 1334082 1930001 1944035 1862641 0 851156 1276047 0 0 0 2166626 1619657 1807443 2065932 1461670 0 0 2102690 1564499 1669166 1730590 0 0 2527549 1983612 0 1339783 0 0 0 0 1327157 0 2316935 2429900 0 1441628 0 1416024 1821511 1442848 1857622 0 1521027 0 1698854 1531291 0 2203606 0 2416048 0 1779292 3250938 0 2398818 3435705 6409038 10022519 3628296 0 4644101 2793025 0 2894316 0 0 3871569 5703904 3591963 0 4435898 3540505 1972457 1765422 0 1873165 4153387 4195589 3451968 0 4602782 2675636 4900092 2529529 2281428 3249158 2863107 3218053 3584956 2216901 2560237 0 2276734 2284222 6256437 3251397 1577338 0 2112033 3308452 0 7189225 0 0 1921993 4036885 3064401 0 2426594 2707074 8035468 3179744 0 2220242 2009962 0 1876460 0 2743959 5900877 3063893 6440917 1673112 2590924 2390707 1566153 2332715 2897599 +AAIEVER MGYG000000243_01362;MGYG000002171_00772 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia,4AM3W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01362 0.5 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 K00384:trxB, TRR; thioredoxin reductase (NADPH) [EC:1.8.1.9] 1.0 none 1.0 0 0 3170007 0 0 0 0 0 0 0 0 0 1686121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2117961 0 3565790 0 0 0 0 3723732 0 0 583323 0 0 0 0 0 0 0 0 0 415623 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546511 0 0 0 0 0 0 0 820360 0 0 0 0 0 0 0 0 0 1150564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 869236 0 554109 0 0 0 0 657838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336546 0 245564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172354 +AAIEVK MGYG000002528_02478;MGYG000001423_03022;MGYG000004594_00959;MGYG000002139_00077;MGYG000003291_00558;MGYG000000312_02404;MGYG000001615_00145;MGYG000000233_02503;MGYG000004785_01840;MGYG000000325_02351;MGYG000002098_00511;MGYG000004087_01282;MGYG000002590_00564;MGYG000001338_02151;MGYG000000179_00100;MGYG000002247_01703;MGYG000001646_00500;MGYG000003486_02360;MGYG000000184_00575;MGYG000004879_02866;MGYG000000217_00686;MGYG000002212_01829;MGYG000000198_00250;MGYG000000118_00274 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.25 186801|Clostridia 1.0 G 0.9583333333333334 Belongs to the PEP-utilizing enzyme family 0.5833333333333334 ppdK 0.9583333333333334 - 1.0 2.7.9.1 0.9583333333333334 ko:K01006 0.9583333333333334 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.9583333333333334 M00169,M00171,M00172,M00173 0.9583333333333334 R00206 0.9583333333333334 RC00002,RC00015 0.9583333333333334 ko00000,ko00001,ko00002,ko01000 0.9583333333333334 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9583333333333334 - 1.0 - 1.0 - 1.0 GT1 0.9166666666666666 MGYG000002528_02478 0.041666666666666664 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.9583333333333334 0.9583333333333334 0.9583333333333334 0.9583333333333334 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 0.9583333333333334 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 0.9583333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 972812 1259958 0 0 0 0 0 0 4485051 0 0 0 0 0 0 0 0 0 0 0 0 1812029 2112209 0 0 0 2048854 0 0 0 2205087 2148922 9023051 3329222 3042354 0 0 0 1533919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3833003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEVKK MGYG000000184_00575 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A luti|m__MGYG000000184 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Phosphoenolpyruvate synthase pyruvate phosphate dikinase 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000184_00575 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 503388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 795691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 642455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1017187 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEVQK MGYG000001707_02428;MGYG000000231_00504;MGYG000001319_00729;MGYG000000280_02154;MGYG000000489_00801;MGYG000003694_01656 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001707_02428 0.16666666666666666 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8512094 0 0 0 0 8973365 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3498165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1073927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIEYAIANDRDSVTLVHK MGYG000002506_00445;MGYG000002535_02428;MGYG000002494_01642 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0538@1|root,COG0538@2|Bacteria,1MW3J@1224|Proteobacteria,1RNMD@1236|Gammaproteobacteria,3XMJ1@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Isocitrate dehydrogenase 1.0 icd 1.0 GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114 1.0 1.1.1.42 1.0 ko:K00031 1.0 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 1.0 M00009,M00010,M00173,M00740 1.0 R00267,R00268,R01899 1.0 RC00001,RC00084,RC00114,RC00626,RC02801 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 e_coli_core.b1136,iAF1260.b1136,iECDH1ME8569_1439.ECDH1ME8569_1071,iEcDH1_1363.EcDH1_2511,iJN746.PP_4011,iJO1366.b1136,iJR904.b1136,iY75_1357.Y75_RS05930,iYL1228.KPN_01144 1.0 CBS,Iso_dh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00445 0.3333333333333333 isocitrate dehydrogenase (NADP(+)). oxalosuccinate carboxylase. Unlike EC 1.1.1.41, oxalosuccinate can be used as a substrate.-!-In eukaryotes, isocitrate dehydrogenase exists in two forms: an NAD(+)-linked enzyme found only in mitochondria and displaying allosteric properties, and a non-allosteric, NADP(+)-linked enzyme that is found in both mitochondria and cytoplasm.-!-The enzyme from some species can also use NAD(+) but much more slowly. D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Glutathione metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids|Peroxisome 1.0 K00031:IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42] 1.0 none 1.0 0 0 0 0 0 199053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236323 0 356611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739647 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994580 0 608242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316225 0 377573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 200551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 205873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 411695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIFGHDANWGR MGYG000000179_03146;MGYG000001619_00943 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,267WZ@186813|unclassified Clostridiales 0.5 186801|Clostridia 1.0 E 1.0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate 1.0 argJ 1.0 - 1.0 2.3.1.1,2.3.1.35 1.0 ko:K00620 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028 1.0 R00259,R02282 1.0 RC00004,RC00064 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ArgJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03146 0.5 amino-acid N-acetyltransferase. | glutamate N-acetyltransferase. N-acetylglutamate synthase. | ornithine transacetylase. Also acts with L-aspartate and, more slowly, with some other amino acids. | Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity. acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate. | L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L- glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00620:argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] 1.0 none 1.0 194287 0 0 165627 0 0 0 0 209508 75715 0 226158 0 162671 112446 0 116722 0 0 87859 147521 0 0 0 267497 269321 58418 0 230213 195658 0 0 0 0 0 73885 225226 0 161190 0 0 90641 0 0 0 0 56395 161338 0 122544 0 200881 69447 0 0 0 0 0 120163 0 0 0 200593 160945 50884 0 187904 0 0 0 0 0 0 100239 139835 0 247067 0 0 294929 0 0 0 0 226770 113002 0 301463 0 273942 280748 0 265074 0 0 222975 283880 0 0 0 86396 124969 241161 0 303603 208471 0 0 0 0 0 238214 154052 0 0 0 0 140125 0 0 0 0 0 96763 0 63248 0 0 0 0 92156 0 0 134959 0 0 0 0 0 246813 0 0 0 0 0 0 0 0 0 0 0 0 2093284 0 0 1848220 0 0 0 0 1671699 1673897 0 1286770 0 1959710 1498931 0 1411335 0 0 2127760 1462955 0 0 0 1312758 1964549 1937491 0 2342271 1820116 0 0 0 0 0 1637407 1936288 0 +AAIFNSPSK MGYG000002775_01545;MGYG000003266_01416 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria,4CURX@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 C 1.0 alcohol dehydrogenase 1.0 adh1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002775_01545 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIFPSKGEMR MGYG000002438_01503 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0162@1|root,COG0162@2|Bacteria,4NF19@976|Bacteroidetes,2FN0B@200643|Bacteroidia,22VXJ@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) 1.0 tyrS 1.0 - 1.0 6.1.1.1 1.0 ko:K01866 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R02918 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 S4,tRNA-synt_1b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01503 1.0 tyrosine--tRNA ligase. tyrosyl-tRNA synthetase. - ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl- tRNA(Tyr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01866:YARS, tyrS; tyrosyl-tRNA synthetase [EC:6.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 993318 0 0 0 0 0 0 0 0 346039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353101 0 0 0 0 0 0 0 0 759011 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055246 0 0 0 0 0 0 0 0 751953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 825212 0 0 0 0 0 0 0 0 558688 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1605480 0 0 0 0 0 0 0 0 2869770 0 0 0 0 0 0 0 0 +AAIGAAR MGYG000000179_05287 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Arabinose_Isome,Fucose_iso_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_05287 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 95533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1640948 160186 0 0 0 0 671072 0 0 0 0 0 0 0 0 0 0 159401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111087 0 0 0 0 201490 0 0 0 0 0 0 0 0 0 0 127887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 245758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1176929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 528710 1572147 0 0 0 0 687187 0 0 0 0 0 0 0 0 0 0 329745 0 +AAIGAGIGIGR MGYG000002293_00140;MGYG000003697_01831 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00140 0.5 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02110:ATPF0C, atpE; F-type H+-transporting ATPase subunit c 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3755648 0 0 0 0 4855740 0 0 0 0 4811255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIGEASDLR MGYG000001627_00478;MGYG000000084_00515 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3WHDD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001627_00478 0.5 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01875:SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 331696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 919157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511485 0 0 0 0 0 0 0 0 +AAIGEGDTLR MGYG000003937_02001 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3WHDD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_02001 1.0 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01875:SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIGEGLQAFC(Carbamidomethyl)IPGSVADHR MGYG000000245_00061;MGYG000002517_01686;MGYG000002492_01963 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 1.0 183925|Methanobacteria 1.0 F 1.0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 1.0 purD 1.0 - 1.0 6.3.4.13 1.0 ko:K01945 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04144 1.0 RC00090,RC00166 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000245_00061 0.3333333333333333 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01945:purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] 1.0 none 1.0 220441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162517 321755 0 0 302529 186176 323913 0 0 0 0 0 0 0 0 0 0 0 311486 0 410545 0 0 0 0 347990 0 0 0 0 0 281953 0 0 0 197105 0 0 154303 0 0 183800 0 0 1024744 0 1457562 0 0 0 0 0 0 0 0 0 837740 803272 1033040 0 0 0 0 961473 0 0 0 0 0 1044669 0 0 0 1138939 0 0 1469635 1114296 0 771037 912800 1259046 0 0 191911 0 0 0 0 0 0 0 0 0 0 251897 106712 0 0 0 0 0 0 0 0 0 0 110621 0 0 0 0 0 0 234723 95540 0 151439 330176 0 0 0 330246 0 0 0 0 0 0 0 0 0 277187 0 322891 0 0 0 0 457967 0 0 0 0 0 483642 0 0 0 332867 0 0 580333 0 0 269323 367127 604830 +AAIGEGLQAFC(Carbamidomethyl)IPGSVADQR MGYG000000205_02543;MGYG000000038_01050;MGYG000000127_05084;MGYG000001496_01287;MGYG000004762_01356;MGYG000002528_00119 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.87 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02543 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 418014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1078892 0 0 0 340711 0 0 0 0 0 0 0 0 0 0 0 0 0 804175 0 999944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIGEGLQAFC(Carbamidomethyl)IPGSVADTR MGYG000001338_01296 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,27IIP@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 S 1.0 GGGtGRT protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GGGtGRT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01296 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409109 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 553585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIGIPED(Methyl[D](Asp->Glu)ELR MGYG000000236_00428 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis_A|m__MGYG000000236 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000236_00428 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10151717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIGIPEE(Glu->Trp)ELR MGYG000000196_04526;MGYG000000029_01860;MGYG000001345_00467;MGYG000003367_00149;MGYG000000044_01913;MGYG000002033_00099;MGYG000002478_01776;MGYG000002905_01187;MGYG000000243_02506;MGYG000001306_00718;MGYG000003221_00520;MGYG000002455_03337;MGYG000000174_01424;MGYG000000355_00809;MGYG000004797_01374;MGYG000000273_02673;MGYG000002575_01735 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.5294117647058824 976|Bacteroidetes 1.0 G 0.6470588235294118 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.5294117647058824 fba 0.6470588235294118 - 1.0 4.1.2.13 0.6470588235294118 ko:K01624 0.6470588235294118 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6470588235294118 M00001,M00003,M00165,M00167,M00344,M00345 0.6470588235294118 R01068,R01070,R01829,R02568 0.6470588235294118 RC00438,RC00439,RC00603,RC00604 0.6470588235294118 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6470588235294118 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04526 0.058823529411764705 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6470588235294118 0.6470588235294118 0.6470588235294118 0.6470588235294118 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6470588235294118 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 0.6470588235294118 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 991249 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIGIPEEE(Glu->Trp)LR MGYG000000196_04526;MGYG000000029_01860;MGYG000001345_00467;MGYG000003367_00149;MGYG000000044_01913;MGYG000002033_00099;MGYG000002478_01776;MGYG000002905_01187;MGYG000000243_02506;MGYG000001306_00718;MGYG000003221_00520;MGYG000002455_03337;MGYG000000174_01424;MGYG000000355_00809;MGYG000004797_01374;MGYG000000273_02673;MGYG000002575_01735 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.5294117647058824 976|Bacteroidetes 1.0 G 0.6470588235294118 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.5294117647058824 fba 0.6470588235294118 - 1.0 4.1.2.13 0.6470588235294118 ko:K01624 0.6470588235294118 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6470588235294118 M00001,M00003,M00165,M00167,M00344,M00345 0.6470588235294118 R01068,R01070,R01829,R02568 0.6470588235294118 RC00438,RC00439,RC00603,RC00604 0.6470588235294118 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6470588235294118 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04526 0.058823529411764705 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6470588235294118 0.6470588235294118 0.6470588235294118 0.6470588235294118 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6470588235294118 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 0.6470588235294118 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 791491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 837474 0 0 0 0 1298441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2805972 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIGIPEEELR MGYG000000196_04526;MGYG000000029_01860;MGYG000001345_00467;MGYG000003367_00149;MGYG000000044_01913;MGYG000002033_00099;MGYG000002478_01776;MGYG000002905_01187;MGYG000000243_02506;MGYG000001306_00718;MGYG000003221_00520;MGYG000002455_03337;MGYG000000174_01424;MGYG000000355_00809;MGYG000004797_01374;MGYG000000273_02673;MGYG000002575_01735 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.5294117647058824 976|Bacteroidetes 1.0 G 0.6470588235294118 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.5294117647058824 fba 0.6470588235294118 - 1.0 4.1.2.13 0.6470588235294118 ko:K01624 0.6470588235294118 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6470588235294118 M00001,M00003,M00165,M00167,M00344,M00345 0.6470588235294118 R01068,R01070,R01829,R02568 0.6470588235294118 RC00438,RC00439,RC00603,RC00604 0.6470588235294118 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6470588235294118 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04526 0.058823529411764705 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6470588235294118 0.6470588235294118 0.6470588235294118 0.6470588235294118 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6470588235294118 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 0.6470588235294118 none 1.0 34388024 34725544 49014167 38569614 45598824 32382409 53843573 37669908 37180862 37146433 49804889 36980217 49573300 33975176 32809976 47706991 37503381 23705857 37880750 30055976 36696840 27466928 40490373 44855873 28684924 36573885 40034651 25411965 37122020 41034142 50844753 36581833 58669911 35516132 34044401 44555610 34831619 56386987 24097021 0 23624401 25244920 33173642 26356959 28487766 24669348 24907236 0 39295871 22920670 48010196 29258304 30090422 42386666 22693057 19307565 25893974 23152860 25825220 24437918 23043843 0 25743943 0 25000108 19974201 26014219 29204569 21210163 26446141 26011783 22522193 0 0 25932518 26015686 20059273 15257707 23560492 17382901 29932888 23167954 25631020 15966698 24681921 20527388 23435693 22128664 32441892 20958696 18384023 24116841 20693150 34275247 17115500 16799487 16394504 16185540 27890195 26469702 19211714 19923045 18902468 25416945 19262120 13301602 25878545 15862759 17278334 11553288 21492235 22963565 19746820 23840845 11076115 9915399 11370638 9502724 11715430 10469905 12771828 11451808 10256412 13547306 16115225 11579167 17570320 10786506 9964537 12434063 11688933 10480432 10825416 8269985 0 0 16932049 9241671 10879302 11092414 12588518 8246344 12085484 11463751 10306325 12205683 11670937 10608308 12602363 14223020 0 0 17778186 13469038 15822960 20504558 32274483 25473786 19638892 21483956 20915914 15301499 18600815 15665895 32602006 13270807 15713446 20894819 18386051 39510965 16856770 23254611 11163467 21624392 33322249 21416641 18502911 18160473 13841807 31529742 20513285 22335724 19923068 17571647 10178417 22435811 20210642 15257126 20044277 17882865 +AAIGIPEEELRK MGYG000000196_04526;MGYG000000029_01860;MGYG000001345_00467;MGYG000003367_00149;MGYG000000044_01913;MGYG000002033_00099;MGYG000002478_01776;MGYG000002905_01187;MGYG000000243_02506;MGYG000001306_00718;MGYG000003221_00520;MGYG000002455_03337;MGYG000000174_01424;MGYG000000355_00809;MGYG000004797_01374;MGYG000000273_02673;MGYG000002575_01735 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 0.5294117647058824 976|Bacteroidetes 1.0 G 0.6470588235294118 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 0.5294117647058824 fba 0.6470588235294118 - 1.0 4.1.2.13 0.6470588235294118 ko:K01624 0.6470588235294118 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6470588235294118 M00001,M00003,M00165,M00167,M00344,M00345 0.6470588235294118 R01068,R01070,R01829,R02568 0.6470588235294118 RC00438,RC00439,RC00603,RC00604 0.6470588235294118 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 0.6470588235294118 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04526 0.058823529411764705 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 0.6470588235294118 0.6470588235294118 0.6470588235294118 0.6470588235294118 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6470588235294118 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 0.6470588235294118 none 1.0 12115702 13302971 20789001 13247603 17221267 12075447 15976157 12205399 14380607 11025366 14960839 11030048 20483675 11480271 10570169 17328056 12795688 8075079 15126546 11734439 12431250 10044695 13310764 15567613 9535392 12198246 12499115 10701797 12069004 13368433 17358624 13305539 23845399 11879844 12382059 14376662 11736799 21591169 7471576 5723952 8489950 8479023 9774648 7453482 6846626 8633711 8274324 8015166 12263756 7151731 18910917 8210415 8995507 12631494 7254944 4073625 7366955 7013218 7605915 10035913 5695362 6607450 7794583 7284351 7905233 5318494 7099181 9031454 5416331 7077788 9591459 7713746 8349731 7693097 7972184 8860192 6374139 6169323 8840458 6604992 10439560 8915851 9037084 6049204 8915306 5922831 8610862 8187095 13752325 7027317 6430291 10311495 7018526 12893166 9309268 6840904 5429581 6197694 12093473 9695286 7487420 5787215 6640538 9637407 7287831 5735364 9742496 6012234 6351701 4454429 7192746 8046186 6959292 9483871 3990247 3695401 4250064 3324109 5154625 4302426 3945294 3957204 3845246 4609910 5938052 4295352 6035032 3723861 5209122 5123687 3450332 3961752 4963406 2845523 4036788 0 6955519 3386628 3843749 4150889 3664183 3202149 3873846 3905225 3594803 4876619 3981103 4455260 5269953 4941564 4398197 3892043 6086806 4310039 4593667 5222144 11027809 8632595 6585445 7072027 8040102 4002383 4849680 5236769 9875293 4266178 5728872 7068391 6019052 10057725 5188805 6825365 3678157 7569442 7847753 11744082 5484000 5651429 5061817 8348750 6306862 6924297 5215796 5094414 3130239 7916424 6698337 5005373 6454383 6216499 +AAIGIPEEQ(Gln->Trp)LR MGYG000001346_02842 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia,22WHF@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_02842 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 988225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIGIPEEW(Trp->Glu)LR MGYG000002438_02632;MGYG000000138_02337 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02632 0.5 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16137715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIGIPEEWLR MGYG000002438_02632;MGYG000000138_02337 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0191@1|root,COG0191@2|Bacteria,4NF5C@976|Bacteroidetes,2FMMR@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Fructose-1,6-bisphosphate aldolase, class II 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02632 0.5 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 1229396 0 149091 0 0 0 196392 0 198785 256845 156884 0 0 0 0 0 404847 0 0 0 0 164466 150755 157212 0 223085 327889 0 119667 0 92114 385830 0 0 104343 0 0 1637677 1532749 1545031 1632928 2333714 1679725 1538999 2515728 1274450 2913889 2140365 4892749 1713520 2071807 1874122 3015797 2078265 552849 2100667 2210076 9736640 1765165 835651 1527167 2039093 1826028 2236920 773831 2250566 4799923 1064975 3438315 1615982 1304680 1852801 1396711 1500254 1449161 767411 873397 1030478 659645 1711528 1058785 0 474314 1050489 897813 0 2239541 875039 820879 815923 0 859211 1260728 163814 694739 2816308 718458 905312 1055894 825343 726138 724503 846858 955099 1963271 998895 1387519 654589 370292 691624 1084996 887816 0 1038564 1238288 986389 529768 0 726597 819909 694810 728341 1015090 741967 2558901 1292187 727409 751558 1037753 864038 335396 861528 731482 8233542 634683 236533 819837 764861 971776 954231 353312 873840 3051493 792370 1950193 836563 831581 833449 976624 737615 705232 2688613 3790643 2732580 3759120 6319137 3403569 2525797 3352752 3253682 4669099 3422541 9273618 5170440 3064450 2045070 4640591 3256347 3448261 2699121 3205839 9635400 9141022 3229156 4554903 0 3137425 4421459 8101870 4686115 10487755 4260258 22423909 1811038 11096003 28038910 5210970 8507840 7602073 +AAIGITNQR MGYG000000164_01754;MGYG000002274_01022;MGYG000000271_02110;MGYG000001338_01881;MGYG000000038_01493;MGYG000002517_00523;MGYG000000198_04024;MGYG000000142_00490 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia 0.375 186801|Clostridia 1.0 C 0.5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_01754 0.125 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1605702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 533285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733679 0 0 0 0 0 0 0 0 0 0 0 +AAIGLAGNNR MGYG000004876_00851 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__|m__MGYG000004876 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4AWF7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004876_00851 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1045862 0 0 0 0 791701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524190 0 0 0 0 850312 0 0 0 0 1157201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 606140 0 0 0 0 733154 0 0 0 0 548837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299062 0 0 0 0 1245123 0 0 0 0 1130860 0 0 0 0 0 0 0 0 0 0 +AAIGNYTR MGYG000001313_00488 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG1028@1|root,COG1028@2|Bacteria,4NG8R@976|Bacteroidetes,2FMB9@200643|Bacteroidia,4AM6Q@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 IQ 1.0 Oxidoreductase, short chain dehydrogenase reductase family protein 1.0 uxuB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_00488 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739116 0 0 0 0 594905 0 0 0 0 639228 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550091 0 0 0 0 331938 0 0 0 0 337936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3122674 0 0 0 0 2668837 0 0 0 0 2248641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220279 0 0 0 0 174484 0 0 0 0 157636 0 0 0 0 0 0 0 0 0 0 +AAIGQINR MGYG000000404_01456 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA11774|s__UBA11774 sp003507655|m__MGYG000000404 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,25XFI@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000404_01456 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02968:RP-S20, rpsT; small subunit ribosomal protein S20 1.0 none 1.0 0 0 0 0 0 0 0 1620559 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1445927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIGTVIGC(Carbamidomethyl)FQDSK MGYG000000187_01839;MGYG000000078_00947 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira 1.0 COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,248C0@186801|Clostridia,25VW8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Glucuronate isomerase 1.0 uxaC 1.0 - 1.0 5.3.1.12 1.0 ko:K01812 1.0 ko00040,ko01100,map00040,map01100 1.0 M00061,M00631 1.0 R01482,R01983 1.0 RC00376 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 LacI,UxaC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000187_01839 0.5 glucuronate isomerase. uronic isomerase. Also converts D-galacturonate to D-tagaturonate. D-glucuronate = D-fructuronate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Metabolic pathways 1.0 K01812:uxaC; glucuronate isomerase [EC:5.3.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1165486 0 0 2162877 0 0 0 0 1512952 0 0 0 0 2121331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 601281 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 387387 0 0 0 0 0 0 0 313488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIHEGDTGSPEVQVALLTAR MGYG000001627_01218;MGYG000004732_00360;MGYG000002059_00069;MGYG000003921_01153;MGYG000004866_00975;MGYG000000084_01969;MGYG000001157_00220;MGYG000003937_00355 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3WK6U@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 - 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001627_01218 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02956:RP-S15, MRPS15, rpsO; small subunit ribosomal protein S15 1.0 none 1.0 447784 0 0 0 588628 0 0 0 504854 0 0 716516 725113 0 0 0 0 1348548 448938 0 0 0 985768 0 668852 472464 0 1296517 656438 0 0 0 0 0 0 0 384122 0 0 0 0 0 305270 0 0 0 0 0 0 1035884 330588 0 0 0 0 550350 0 0 0 0 586762 0 0 0 0 463678 0 0 0 0 0 0 0 0 269605 0 0 0 0 0 0 0 0 0 0 0 0 613672 0 0 0 0 0 493102 0 0 0 0 321594 0 0 0 0 415424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 628445 0 0 0 0 0 657613 0 0 0 0 862452 0 0 0 0 460054 0 0 0 0 0 0 0 0 0 0 543160 0 0 0 361806 0 0 0 400794 0 0 1934922 519469 0 0 0 0 1195701 303119 0 0 0 1021759 0 334177 158692 0 1329776 387845 0 0 0 0 0 0 0 325154 0 +AAIHFVDPEDLGMK MGYG000002163_00221 genome d__Archaea|p__Methanobacteriota|c__Methanobacteria|o__Methanobacteriales|f__Methanobacteriaceae|g__Methanobrevibacter_A|s__Methanobrevibacter_A smithii|m__MGYG000002163 1.0 COG4007@1|root,arCOG03196@2157|Archaea,2XTKJ@28890|Euryarchaeota,23PHM@183925|Methanobacteria 1.0 183925|Methanobacteria 1.0 C 1.0 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT 1.0 hmd 1.0 - 1.0 1.12.98.2 1.0 ko:K13942 1.0 ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200 1.0 M00567 1.0 R04455 1.0 RC00202 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 HMD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002163_00221 1.0 5,10-methenyltetrahydromethanopterin hydrogenase. nonmetal hydrogenase. Does not catalyze the reduction of artificial dyes.-!-Does not by itself catalyze a H2/H(+) exchange reaction.-!-Does not contain nickel or iron-sulfur clusters.-!-Formerly EC 1.12.99.4. 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 = 5,10- methylenetetrahydromethanopterin + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K13942:hmd; 5,10-methenyltetrahydromethanopterin hydrogenase [EC:1.12.98.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 880216 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIIAEYGR MGYG000000233_02689;MGYG000000205_00957 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,220GG@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 - 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02689 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02956:RP-S15, MRPS15, rpsO; small subunit ribosomal protein S15 1.0 none 1.0 1530115 0 0 1321174 0 0 0 1639395 0 0 0 1185467 0 0 0 0 0 780121 1517446 0 0 0 505967 0 0 1312265 0 641619 0 1171513 0 0 0 1777091 0 0 1518292 0 738626 0 0 1145486 0 0 0 1398720 0 0 0 3862532 0 0 0 0 0 406647 1091932 0 0 0 1063824 0 0 1041105 0 599319 0 2847846 0 0 0 1162441 0 0 987132 0 1070096 0 0 0 0 0 0 644659 0 0 0 473770 0 0 0 0 0 9478326 490190 0 0 0 791507 0 0 446195 0 790396 0 619961 0 0 0 376804 0 0 602982 0 831571 0 0 1000089 0 0 0 420248 0 0 0 837811 0 0 0 0 0 3325723 607595 0 0 0 313338 0 0 309313 0 2212041 0 355118 0 0 0 410387 0 0 845834 0 1422872 0 0 2056659 0 0 0 551363 0 0 0 222627 0 0 0 0 0 303654 1592007 0 0 0 637848 0 0 217562 0 1583275 0 305920 0 0 0 694854 0 0 1455301 0 +AAIIAEYGRK MGYG000000233_02689;MGYG000000205_00957 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,220GG@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 - 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02689 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02956:RP-S15, MRPS15, rpsO; small subunit ribosomal protein S15 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6972538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIIALK MGYG000003697_01278;MGYG000002960_02182;MGYG000003535_00725 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia 0.6666666666666666 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01278 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 108967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82814 0 0 0 0 82067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1567700 0 0 0 0 1557705 0 0 0 0 919491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIIEQYGR MGYG000002445_01948 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Clostridium_Q|s__Clostridium_Q sp003024715|m__MGYG000002445 1.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,220GG@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome 1.0 rpsO 1.0 - 1.0 - 1.0 ko:K02956 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S15 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002445_01948 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02956:RP-S15, MRPS15, rpsO; small subunit ribosomal protein S15 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIIGGC(Carbamidomethyl)AGTSC(Carbamidomethyl)VLTGK MGYG000001338_03122 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,3WGKF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP 1.0 pncB 1.0 - 1.0 6.3.4.21 1.0 ko:K00763 1.0 ko00760,ko01100,map00760,map01100 1.0 - 1.0 R01724 1.0 RC00033 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 NAPRTase,QRPTase_C,QRPTase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_03122 1.0 nicotinate phosphoribosyltransferase. nicotinic acid phosphoribosyltransferase. The enzyme, which is involved in pyridine nucleotide recycling, can form beta-nicotinate D-ribonucleotide and diphosphate from nicotinate and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) in the absence of ATP.-!-However, when ATP is available the enzyme is phosphorylated resulting in a much lower Km for nicotinate.-!-The phospho-enzyme is hydrolyzed during the transferase reaction, regenerating the low affinity form.-!-The presence of ATP shifts the products/substrates equilibrium from 0.67 to 1100.-!-Formerly EC 2.4.2.11. 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate = ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate. 1.0 1.0 1.0 1.0 Nicotinate and nicotinamide metabolism|Metabolic pathways 1.0 K00763:pncB, NAPRT1; nicotinate phosphoribosyltransferase [EC:6.3.4.21] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 354650 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 563699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIIGGGNVAMDAAR MGYG000002884_00905 genome d__Bacteria|p__Cyanobacteria|c__Vampirovibrionia|o__Gastranaerophilales|f__Gastranaerophilaceae|g__UMGS951|s__UMGS951 sp900547155|m__MGYG000002884 1.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 'glutamate synthase 1.0 gltA 1.0 - 1.0 1.4.1.13,1.4.1.14 1.0 ko:K00266 1.0 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 1.0 - 1.0 R00093,R00114,R00248 1.0 RC00006,RC00010,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,NAD_binding_8,Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002884_00905 1.0 glutamate synthase (NADPH). | glutamate synthase (NADH). NADPH-glutamate synthase. | NADH-glutamate synthase. The reaction takes place in the opposite direction.-!-The protein is composed of two subunits, alpha and beta.-!-The alpha subunit is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.4).-!-The beta subunit transfers electrons from the cosubstrate.-!-The NH3 is channeled through a 31 A channel in the active protein.-!-In the absence of the beta subunit, coupling between the two domains of the alpha subunit is compromised and some ammonium can be produced.-!-In the intact alphabeta complex, ammonia production only takes place as part of the overall reaction.-!-Formerly EC 2.6.1.53. | A flavoprotein (FMN).-!-The reaction takes place in the direction of L-glutamate production.-!-The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2). 2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH. | 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K00266:gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1075381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 461158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIIGLTK MGYG000002535_01106;MGYG000002494_03981;MGYG000003372_03990 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1028@1|root,COG1028@2|Bacteria,1MURZ@1224|Proteobacteria,1RMUM@1236|Gammaproteobacteria,3XMSX@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 1.0 IQ 1.0 oxidoreductase activity 0.6666666666666666 ucpA 1.0 - 1.0 1.1.1.100 1.0 ko:K00059,ko:K18335 1.0 ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212 1.0 M00083,M00572 1.0 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R10690,R11671 1.0 RC00029,RC00089,RC00117 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002535_01106 0.3333333333333333 3-oxoacyl-[acyl-carrier-protein] reductase. - Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates. a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Fatty acid biosynthesis|Prodigiosin biosynthesis|Biotin metabolism|Biosynthesis of unsaturated fatty acids|Metabolic pathways|Microbial metabolism in diverse environments|Fatty acid metabolism 1.0 K00059:fabG, OAR1; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]|K18335:E1.1.1.434; 2-dehydro-3-deoxy-L-fuconate 4-dehydrogenase [EC:1.1.1.434] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4895830 0 0 0 1454428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498615 0 357767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIIGSPTR MGYG000002528_02599;MGYG000000028_00892 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,268EK@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Iron-containing alcohol dehydrogenase 1.0 dhaD 1.0 - 1.0 1.1.1.6 1.0 ko:K00005 1.0 ko00561,ko00640,ko01100,map00561,map00640,map01100 1.0 - 1.0 R01034,R10715,R10717 1.0 RC00029,RC00117,RC00670 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02599 0.5 glycerol dehydrogenase. NAD-linked glycerol dehydrogenase. Also acts on 1,2-propanediol. glycerol + NAD(+) = dihydroxyacetone + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Propanoate metabolism|Metabolic pathways 1.0 K00005:gldA; glycerol dehydrogenase [EC:1.1.1.6] 1.0 none 1.0 0 0 0 0 0 553450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399324 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5582253 0 1266935 0 0 0 0 3289362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254282 0 188281 0 0 0 0 330634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIIHGLK MGYG000002052_00761 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Stomatobaculum|s__|m__MGYG000002052 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002052_00761 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2964869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIIIAVK MGYG000001300_02045 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3WG8A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Participates in both transcription termination and antitermination 1.0 nusA 1.0 - 1.0 - 1.0 ko:K02600 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009,ko03021 1.0 - 1.0 - 1.0 - 1.0 KH_5,NusA_N,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02045 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02600:nusA; transcription termination/antitermination protein NusA 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545569 0 0 0 0 258775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428525 0 0 0 0 293361 334019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIILDDKAPESTPTVYR MGYG000002477_01443 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_A|s__Citrobacter_A amalonaticus|m__MGYG000002477 1.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3ZJCJ@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 F 1.0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 deoA 1.0 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 1.0 2.4.2.4 1.0 ko:K00758 1.0 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 1.0 - 1.0 R01570,R02484,R08222,R08230 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 1.0 Glycos_trans_3N,Glycos_transf_3,PYNP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002477_01443 1.0 thymidine phosphorylase. pyrimidine phosphorylase. In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.-!-Formerly EC 2.4.2.23. phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Bladder cancer 1.0 K00758:deoA, TYMP; thymidine phosphorylase [EC:2.4.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1099246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIITTPIEK MGYG000000050_00899;MGYG000000806_00539;MGYG000000201_00039;MGYG000000301_01719;MGYG000001338_03041 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,3XYNY@572511|Blautia 0.8 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.87 0.8 cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CobW_C,cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000050_00899 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618750 548640 0 0 0 0 290382 +AAIITTPWDSIR MGYG000002517_01323 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 CobW P47K family protein 1.0 cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CobW_C,cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01323 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 312499 0 223005 108186 0 0 0 203343 0 0 0 102468 0 179441 0 202436 0 208035 0 0 0 0 0 209448 0 0 0 0 0 0 164624 0 180702 184951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121744 0 0 0 0 0 0 0 0 0 0 0 0 1109676 0 0 982835 421294 212090 681847 1407095 1068160 587557 402725 702418 0 1363686 1087568 537929 804557 0 1051899 1032339 1030208 0 0 0 1219276 1091290 871258 0 0 924083 0 0 200276 1165298 1196165 1048288 1199102 125992 1616643 0 1290636 0 2108471 1883788 1187431 1339703 1637959 1688905 1171807 1152620 0 1391386 1938797 1474931 1674899 0 1990258 1727383 1301116 1113872 0 1256101 2235026 1607630 2191004 0 0 1882370 0 0 874491 2186788 1418691 1451168 1887724 1211404 +AAIITTPWDSIRGEQILK MGYG000002517_01323 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 CobW P47K family protein 1.0 cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CobW_C,cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01323 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 204094 0 156064 0 306392 67460 0 0 0 0 254675 205577 158615 77618 0 0 79068 0 0 173308 173387 200747 0 63501 169790 0 0 0 0 105073 0 0 0 0 0 0 130786 0 0 0 0 0 0 0 0 0 166315 0 150660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253142 0 191503 1524803 82371 234314 0 0 435097 0 74553 177349 111539 77798 0 0 64042 0 0 211574 96389 144534 0 0 206442 195251 242669 0 0 154234 107717 0 141050 0 190279 0 282974 134528 543539 0 135514 574274 230528 72403 0 0 658446 0 348393 374535 127986 686194 0 0 302164 0 0 448801 277030 268299 0 0 724383 650725 499164 0 0 524595 229622 0 68701 0 784128 0 660284 330432 246090 0 905170 0 827985 1161848 0 0 967704 0 1014741 593985 1491786 912463 0 0 819762 0 0 467796 212032 0 0 1038939 443804 523365 372711 0 0 496466 1499947 0 923368 0 0 0 4798545 3092038 +AAIKNPR MGYG000001647_00185;MGYG000000022_02788;MGYG000000312_02404;MGYG000000278_00304;MGYG000003899_02226;MGYG000003166_00833;MGYG000002707_01357;MGYG000002545_01217;MGYG000002274_02693;MGYG000004726_03204;MGYG000002105_00879;MGYG000001300_02837;MGYG000001255_00900;MGYG000002953_01784;MGYG000002040_00906 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.6 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.9333333333333333 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001647_00185 0.06666666666666667 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 101175 0 0 0 0 0 0 0 0 0 0 0 0 132200 0 431612 197589 0 176135 0 338645 0 0 0 0 377654 0 0 0 0 0 0 0 0 0 0 0 0 158239 0 0 0 0 0 0 0 0 0 0 0 0 309227 0 0 753430 0 85903 0 601102 0 0 0 0 453263 0 0 0 0 0 0 0 0 0 247862 0 0 350308 0 263430 0 233157 0 0 0 0 0 0 0 0 408541 0 0 251282 0 773626 0 266179 0 0 0 0 432349 0 0 0 0 448477 0 0 0 0 175573 0 0 199516 0 99524 0 832504 0 0 0 0 0 0 0 0 215411 0 338774 205576 0 85751 0 80133 0 0 0 0 450076 0 0 0 0 198353 0 0 0 0 256603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211339 0 0 0 0 43496 0 0 0 0 109182 0 0 0 0 0 0 0 0 0 0 +AAILAEEER MGYG000002438_01848 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,22WFC@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Domain of Unknown Function (DUF349) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01848 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306067 0 0 0 0 0 0 0 0 0 0 0 0 0 1456283 0 0 0 0 0 0 0 0 669885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1613829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 700179 0 0 0 0 1476755 0 0 0 0 0 0 0 0 1795837 0 0 0 0 0 0 0 0 2146764 0 0 0 0 0 0 0 0 +AAILAEEERVK MGYG000002438_01848 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,22WFC@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Domain of Unknown Function (DUF349) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01848 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1634728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1407814 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 711149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAILANK MGYG000001338_00669 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia,3XYGM@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 araB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_00669 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1324425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1867126 0 0 0 0 1001289 0 0 1582537 0 0 0 0 0 0 0 +AAILDR MGYG000001346_01624;MGYG000004876_03444;MGYG000002549_04587 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000001346_01624 0.3333333333333333 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAILLDTK MGYG000002494_00983 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,3XMTB@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Pyruvate kinase 1.0 pykF 1.0 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 2.7.1.40 1.0 ko:K00873 1.0 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050 1.0 R00200,R00430,R01138,R01858,R02320 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iECO103_1326.ECO103_1819,iPC815.YPO2393 1.0 PK,PK_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00983 1.0 pyruvate kinase. phosphoenol transphosphorylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Purine metabolism|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|Glucagon signaling pathway|Type II diabetes mellitus|Human papillomavirus infection|Viral carcinogenesis|Central carbon metabolism in cancer 1.0 K00873:PK, pyk; pyruvate kinase [EC:2.7.1.40] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAILLDTKGPEIR MGYG000002494_00983 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,3XMTB@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Pyruvate kinase 1.0 pykF 1.0 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 2.7.1.40 1.0 ko:K00873 1.0 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050 1.0 R00200,R00430,R01138,R01858,R02320 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iECO103_1326.ECO103_1819,iPC815.YPO2393 1.0 PK,PK_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00983 1.0 pyruvate kinase. phosphoenol transphosphorylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Purine metabolism|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|Glucagon signaling pathway|Type II diabetes mellitus|Human papillomavirus infection|Viral carcinogenesis|Central carbon metabolism in cancer 1.0 K00873:PK, pyk; pyruvate kinase [EC:2.7.1.40] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1012633 0 0 0 0 0 0 0 0 0 1368245 0 0 0 0 0 1139651 0 0 0 0 0 1056993 0 0 0 0 0 0 0 1384730 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 240909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAILPK MGYG000002494_02542 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,1RPCQ@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 C 1.0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases 1.0 qor 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003960,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016651,GO:0016655,GO:0017091,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:1901363 1.0 1.6.5.5 1.0 ko:K00344 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N,ADH_zinc_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02542 1.0 NADPH:quinone reductase. zeta-crystallin. Specific for NADPH.-!-Catalyzes the one-electron reduction of certain quinones, with the orthoquinones 1,2-naphthoquinone and 9,10-phenanthrenequinone being the best substrates.-!-Dicoumarol (cf. EC 1.6.5.2) and nitrofurantoin are competitive inhibitors with respect to the quinone substrate.-!-The semiquinone free-radical product may be non-enzymically reduced to the hydroquinone or oxidized back to quinone in the presence of O2.-!-Abundant in the lens of the eye of some mammalian species. 2 a quinone + H(+) + NADPH = 2 a 1,4-benzosemiquinone + NADP(+). 1.0 1.0 1.0 1.0 - 1.0 K00344:qor, CRYZ; NADPH:quinone reductase [EC:1.6.5.5] 1.0 none 1.0 0 213751 173333 211104 0 293313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267099 0 278891 0 0 0 0 205091 0 0 0 102319 0 0 0 0 221589 0 527870 576272 329891 0 662535 0 0 0 0 0 0 0 0 0 0 0 0 0 0 504037 754063 0 662847 0 0 0 0 574593 0 0 0 695894 0 0 0 0 543494 0 204435 110175 219409 0 98756 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403135 77183 0 67173 0 0 0 0 77129 0 0 0 0 0 0 0 0 65725 0 0 112019 77570 0 80175 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77531 92555 0 242325 0 0 0 0 91129 0 0 0 292722 0 0 0 0 103012 0 98115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 62288 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153580 +AAILPLSK MGYG000002794_00630;MGYG000000416_00486;MGYG000001733_00367;MGYG000002926_00944;MGYG000002882_01752;MGYG000004196_01635;MGYG000002720_01072;MGYG000002057_00097;MGYG000002116_00583;MGYG000002715_00885 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales 1.0 COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,2N745@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Anticodon binding domain 1.0 glyQS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 1.0 6.1.1.14 1.0 ko:K01880 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03654 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_00630 0.1 glycine--tRNA ligase. glycyl-tRNA synthetase. - ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01880:GARS, glyS1; glycyl-tRNA synthetase [EC:6.1.1.14] 1.0 none 1.0 0 0 511996 0 0 0 874026 902873 855533 790227 474420 0 550981 0 0 504795 765406 0 0 0 0 0 0 0 0 1062573 915511 0 0 659447 0 0 547906 783791 1161198 1352163 1066942 547056 557933 0 263675 0 0 0 340478 0 0 0 0 0 237756 0 0 230503 112153 0 0 0 0 0 0 0 0 424883 0 0 0 369462 0 0 256523 494709 591353 454363 547818 237268 1086233 0 529621 0 0 0 0 0 732618 0 0 0 585355 0 0 718600 967984 0 0 0 0 0 0 0 0 815277 1074960 0 0 0 0 0 0 0 0 0 0 0 248439 0 0 0 0 0 225037 106570 219542 0 0 0 143391 0 0 196440 193094 0 0 0 0 0 0 0 0 291758 0 0 0 0 0 0 190754 226671 0 0 186925 163054 1855763 0 0 0 0 0 1223280 1027061 0 1616118 0 0 375110 0 0 0 1479002 0 0 0 0 0 0 0 0 1058005 1388454 0 0 0 0 0 900199 1128731 832102 0 1091735 1036743 +AAILTR MGYG000004828_01320;MGYG000002485_00846;MGYG000001300_02570 domain d__Bacteria 1.0 COG0240@1|root,COG0240@2|Bacteria,378MQ@32066|Fusobacteria 0.6666666666666666 32066|Fusobacteria 0.6666666666666666 I 1.0 Glycerol-3-phosphate dehydrogenase 1.0 gpsA 1.0 - 1.0 1.1.1.94 1.0 ko:K00057 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00842,R00844 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 NAD_Gly3P_dh_C,NAD_Gly3P_dh_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004828_01320 0.3333333333333333 glycerol-3-phosphate dehydrogenase [NAD(P)(+)]. L-glycerol-3-phosphate:NAD(P) oxidoreductase. The enzyme from Escherichia coli shows specificity for the B side of NADPH. (1) NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH. (2) NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00057:gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] 1.0 none 1.0 0 0 310545 0 0 0 358520 0 0 293363 0 604135 0 701274 0 430681 0 0 306015 0 0 0 0 0 0 496016 0 0 0 0 0 0 234194 0 0 329309 608656 427947 1082092 0 899106 0 0 0 962728 0 0 976182 0 652875 0 843202 0 814256 0 0 1232063 0 0 0 0 0 0 848523 0 0 0 0 0 0 1103693 0 0 881533 839556 923987 811208 0 168873 0 0 0 0 0 0 477252 0 158348 0 0 0 490637 0 0 215735 0 0 0 0 0 0 1023166 0 0 0 0 0 0 734795 0 0 0 154817 305992 1148035 0 254130 0 0 0 945848 0 0 943239 0 277957 0 786961 0 771579 0 0 209624 0 0 0 0 0 0 606410 0 0 0 0 0 0 373668 0 0 732838 479021 968667 1110155 0 394287 0 0 0 456715 0 0 1406816 0 346355 0 1621219 0 173087 0 0 671458 0 0 0 0 0 0 1094019 0 0 0 0 0 0 0 0 0 1019285 513926 904137 +AAIMKEYAR MGYG000000216_02226 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp003474435|m__MGYG000000216 1.0 COG0677@1|root,COG0677@2|Bacteria,1TPXY@1239|Firmicutes,4H3DG@909932|Negativicutes 1.0 909932|Negativicutes 1.0 M 1.0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family 1.0 - 1.0 - 1.0 - 1.0 ko:K02474 1.0 ko00520,map00520 1.0 - 1.0 R06894 1.0 RC00291 1.0 ko00000,ko00001,ko01000,ko01005 1.0 - 1.0 - 1.0 - 1.0 UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000216_02226 1.0 - - - - 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 K02474:wbpO; UDP-N-acetyl-D-glucosamine/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIMLAQK MGYG000000243_02805 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,2FMY9@200643|Bacteroidia,4AM1G@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine 1.0 hisD 1.0 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.1.1.23 1.0 ko:K00013 1.0 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 1.0 M00026 1.0 R01158,R01163,R03012 1.0 RC00099,RC00242,RC00463 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2,DUF559,Histidinol_dh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02805 1.0 histidinol dehydrogenase. - Also oxidizes L-histidinal.-!-The Neurospora enzyme also catalyzes the reactions of EC 3.5.4.19 and EC 3.6.1.31. H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH. 1.0 1.0 1.0 1.0 Histidine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00013:hisD; histidinol dehydrogenase [EC:1.1.1.23] 1.0 none 1.0 0 0 1068972 0 0 0 0 0 0 0 0 0 1256022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1046775 0 0 0 0 1122075 0 0 0 0 0 0 0 0 0 0 0 0 808937 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 131269 0 0 0 0 0 0 0 178690 0 0 0 0 0 0 0 0 0 234179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133516 0 0 0 0 128428 0 0 327873 0 0 0 0 0 0 0 0 0 362539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 404788 0 0 0 0 377081 0 0 0 0 0 0 0 0 0 0 0 0 321169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIN(Deamidated)N(Deamidated)GYDMDIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.07692307692307693 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 734289 0 419280 0 394451 517115 0 0 561428 0 741624 797932 0 541696 955917 0 0 0 0 809264 709401 297772 0 0 915621 554503 679108 0 0 835251 0 0 0 907573 0 530732 443144 0 0 0 0 0 235279 0 0 0 591609 0 346379 0 0 219712 349707 0 0 0 0 222118 334832 0 0 200465 483652 448458 293697 0 0 0 0 0 0 378179 0 0 291415 279356 617111 0 426804 0 0 342287 0 0 605481 0 0 458125 0 448476 539662 0 0 0 0 642633 440554 0 0 0 743744 560549 598656 0 0 838279 0 0 676435 537774 0 453980 495464 551626 3935814 0 0 0 2872654 1366085 0 0 3895476 0 0 2504502 0 5119890 4175370 0 0 0 0 3518479 2735497 0 0 0 4212195 3107105 4496842 0 0 4230193 0 0 0 174992 0 0 5135207 0 1412405 0 2713236 0 718362 1752637 0 0 1909711 0 1839489 2878019 0 2455667 2359786 0 0 0 0 990975 2154692 1307679 0 1997750 2054718 1881329 2220660 0 0 1304109 0 0 1963041 1757299 0 2144161 2108112 1690064 +AAIN(Deamidated)NGYDM(Oxidation)DIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.07692307692307693 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIN(Deamidated)NGYDMDIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.07692307692307693 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAINDPLLTEQIDR MGYG000000243_01926 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG2942@1|root,COG2942@2|Bacteria,4NEFV@976|Bacteroidetes,2FN6V@200643|Bacteroidia,4AM2U@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG COG2942 N-acyl-D-glucosamine 2-epimerase 1.0 - 1.0 - 1.0 5.1.3.8 1.0 ko:K01787 1.0 ko00520,map00520 1.0 - 1.0 R01207 1.0 RC00290 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 GlcNAc_2-epim 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01926 1.0 N-acylglucosamine 2-epimerase. N-acetyl-D-glucosamine 2-epimerase. Requires catalytic amounts of ATP. an N-acyl-D-glucosamine = an N-acyl-D-mannosamine. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism 1.0 K01787:RENBP; N-acylglucosamine 2-epimerase [EC:5.1.3.8] 1.0 none 1.0 0 0 1633322 2289965 0 1057787 0 1195821 997443 0 0 0 0 805059 0 0 838255 0 0 0 784651 854709 0 1332929 0 0 844280 0 0 0 1323274 0 1273099 1261841 0 0 0 1236339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 593938 618408 0 586860 0 0 675885 0 0 0 0 572001 0 0 533824 0 0 0 709480 0 0 470955 0 0 482210 0 0 0 528490 0 505756 760047 0 0 0 247545 0 0 0 0 0 0 0 450063 281796 0 0 0 0 270381 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAINFAK MGYG000001871_01381;MGYG000000077_00330;MGYG000000077_01903;MGYG000000262_02730 domain d__Bacteria 1.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,25YA2@186806|Eubacteriaceae 0.5 186801|Clostridia 0.75 H 0.5 Pyruvate formate lyase-like 0.75 - 1.0 - 1.0 2.3.1.54,4.3.99.4 0.75 ko:K00656,ko:K20038 0.75 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 0.75 - 1.0 R00212,R06987 0.75 RC00004,RC01181,RC02742,RC02833 0.75 ko00000,ko00001,ko01000 0.75 - 1.0 - 1.0 - 1.0 Gly_radical,PFL-like 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001871_01381 0.25 formate C-acetyltransferase. | choline trimethylamine-lyase. pyruvate formate-lyase. The enzyme utilizes a glycine radical to break the C-N bond in choline.-!-Found in choline-degrading anaerobic bacteria. acetyl-CoA + formate = CoA + pyruvate. | choline = acetaldehyde + trimethylamine. 0.75 0.75 0.75 0.75 Pyruvate metabolism|Propanoate metabolism|Butanoate metabolism|Metabolic pathways|Microbial metabolism in diverse environments 0.75 K00656:E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]|K20038:cutC; choline trimethylamine-lyase [EC:4.3.99.4] 0.75 none 1.0 416827 2842177 389415 393366 4779069 2404775 163264 2008870 751282 1982910 1836076 1555774 4087291 1331186 3355351 3247809 1426797 0 2327665 2961529 1497014 3300300 0 604236 2770090 1201173 491692 0 516862 413314 337518 2776427 1008057 1475289 1242808 647686 287399 783343 564800 0 158111 0 157790 74001 1014838 220769 505737 0 0 124397 0 0 301576 0 0 0 1246705 699550 0 0 0 0 130139 469015 0 0 0 0 70774 110603 0 0 684091 588270 458012 0 14119975 8648318 2635601 16580139 1842188 9172105 3214095 8946641 5389165 11228349 4318799 4910885 10141110 12528845 20312584 10153160 6147651 0 13638629 19940157 12007306 14048386 0 7162007 24172973 11989256 17259726 0 2574311 7651907 2736842 6163165 4954668 9596440 9559845 4404952 10872203 2337762 7011134 7976398 4163762 9881670 6343439 11326778 11445056 6061469 5969240 16954722 5692844 3132174 7446249 6984534 5195072 16605022 9797439 0 4142680 13081491 2973800 9586894 0 10162561 4124621 1956828 5828678 0 8427273 5805924 5470071 5523355 6403078 2289628 4892323 3907284 3117455 6283442 90460 321542 344152 111807 215127 198985 335627 128562 195217 477973 105238 109703 0 85999 135921 319383 173203 0 124579 190500 0 265314 0 0 0 208975 0 0 296611 346648 117568 0 0 0 105290 169713 126578 200440 +AAINN(Ammonia-loss)GYDMDIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.07692307692307693 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 492330 0 293555 974805 0 423332 584597 601595 811066 835500 0 0 0 527793 1078815 0 0 0 0 469648 987732 763156 0 0 819630 645766 641373 0 0 337244 0 0 0 0 495222 485908 642139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402181 0 577843 0 0 0 330702 357875 360455 0 0 0 0 338822 350440 0 0 0 0 337426 232164 0 0 0 557626 660851 248466 0 0 724285 0 0 547479 0 380350 242159 672443 680835 1724780 0 748467 2251064 0 739403 1488093 2080797 3343269 1643663 0 0 0 2264590 2595885 0 0 0 0 2654379 1332769 0 0 0 2441275 1677788 1974709 0 0 1921757 0 0 460277 0 2647600 2191128 1975290 740447 1420459 0 1952336 0 0 1439893 2232504 1848322 1672234 2603966 0 0 0 2621926 2720052 0 0 0 0 858312 2176941 1324214 0 2202778 2310447 1839228 2192958 0 0 688748 0 0 2506800 0 1579140 2446607 2303326 1889308 +AAINN(Deamidated)GYDM(Oxidation)DIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.07692307692307693 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 563872 424458 246692 858098 625752 506549 1171641 794133 552661 930859 686370 738795 0 551482 1365214 1283643 1017979 0 888487 677259 669550 958664 0 0 839598 457427 502831 0 308359 664861 0 0 572721 738258 384357 312124 650979 435790 335730 0 0 411168 268601 0 0 0 0 297648 315520 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360639 0 0 0 0 0 0 0 349442 372590 0 0 606230 861547 651731 522868 1049869 344111 1134595 727458 566495 621631 381133 579693 0 306151 505458 792747 475566 0 641037 613334 827086 350994 0 1240795 737067 846175 649310 0 804788 807120 0 0 805863 405830 353189 933865 665778 619524 3093781 1579420 1065184 3010977 2346615 1569090 1720754 3329495 0 2136922 1136826 2431307 0 4316890 4144632 1598528 2523147 0 3041130 3370656 2523555 391097 0 768267 3288791 2775031 3470534 0 1674482 3105881 0 0 1791364 1263337 3046866 2323762 3371272 0 1645130 1501742 3205043 245661 564486 1893470 2820650 1430179 2055080 4178604 3171276 3442305 0 4422319 3145173 1289531 2278154 0 2932240 914969 2687878 1152880 0 2202243 3210256 1937662 3057180 0 765959 926603 0 0 3720056 2630537 1782100 2799497 2347494 2188828 +AAINN(Deamidated)GYDMDIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.07692307692307693 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 12175226 8924623 5800238 14005310 8041379 0 5585531 13969727 0 0 11785558 15824299 9097495 8544564 13339035 6819393 0 1785037 0 0 13925593 0 2146370 0 0 0 11023647 2539511 5499616 14576072 465259 3762054 4439616 12458731 10593288 8759023 10539171 3639554 1846190 1122397 1723055 0 851413 1058567 1301291 0 807660 1264626 411207 0 1640147 1587444 1917214 1430840 1156451 7648314 1532776 0 1690474 963000 4548690 0 1832311 644626 0 5536207 1059570 2233244 1117083 1530357 2079489 1835491 921977 1580770 1610407 703515 2482826 3590813 10075007 6038798 1267809 3156133 1871280 2381526 0 2269433 0 0 0 0 2369579 0 4483481 2539606 8554945 7578404 2019494 3609542 3627517 1208488 9657487 10047766 9133142 4864630 1523165 2702028 3934236 4128019 0 2257681 2460788 6577813 0 0 53004488 13911944 0 0 31455464 18418328 26418448 50150012 57113059 0 15422839 30183659 14037650 65747159 58187778 27452811 41035324 1933017 40933449 49280491 29372568 6306044 2284803 6625991 48836410 0 0 483541 14961822 39783890 15119337 17625658 13583104 22419821 39652354 34988385 66243538 13907033 0 0 0 444962 0 0 0 0 0 0 0 49124617 0 43096572 0 26868000 0 245802 0 19140114 0 0 356593 0 0 31842881 0 495891 0 0 0 0 0 29429389 0 0 38548744 27545464 +AAINNGYDM(Oxidation)DIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.07692307692307693 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 821527 613291 318525 1461013 861882 945281 871372 821631 948192 1134177 985447 1350327 850502 830819 1512392 1594869 2405967 0 1007377 985749 1234320 1028229 0 596222 1415366 904351 870316 0 572349 1141472 309771 296137 338986 957834 1050014 767596 847007 416473 0 325753 0 0 321526 178047 0 262737 427920 0 230074 0 0 220918 0 0 309927 0 0 156723 0 279782 0 239062 295660 0 0 0 170033 0 330363 245247 0 244985 0 136567 0 361638 881020 1130639 1390990 1131650 515040 438794 937935 697930 907299 720301 788754 962752 720766 931459 898585 821743 672240 0 800735 782758 756412 333527 0 684672 876259 1073882 898953 0 832744 854196 649774 550969 1104311 751949 660279 1041767 1019928 1415720 0 1209829 1103459 3947613 3127084 1487337 0 4172295 4984453 2506207 1647676 2966272 1258752 4080394 3900628 1794195 3404352 0 3332263 3730601 2695800 272158 0 1267708 3779421 3442984 3117295 0 1412798 3592413 1671362 1986213 1416722 1671317 3863541 2708891 3982859 1222726 2481011 1789882 2772432 161739 755175 2147225 2597210 2073972 2139831 3498064 2868637 2649622 1150307 4263651 2909788 1989314 2478922 0 2482517 1619753 2589770 2112088 0 2611635 3739418 2050640 4027149 0 812936 1123430 1972650 692634 2991953 2339200 2330238 3054631 2589285 2401270 +AAINNGYDMDIK MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.07692307692307693 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 13418921 8629178 7846564 23011437 12293853 11100809 11960623 14186770 14966853 20371396 16811751 23734780 11723465 11963557 19662039 9232309 13738773 2159332 13448695 13516944 17013699 9562409 2772123 6088464 20706676 12998332 13064108 1999803 7986470 16541430 3457986 3213450 5518042 13128076 10054543 12147547 12781113 7199117 1119763 798588 1491286 1209657 2122322 650564 1205046 672455 929150 950736 1995796 1001773 1564186 984969 692269 1371195 1004514 7207928 657590 1115222 376478 507359 4612492 641511 982523 899872 893458 5743015 775205 1082508 985085 378706 2066424 892229 476357 1010848 747770 1958430 9716765 3631758 9791120 7024126 4235845 2636198 8350058 6880135 8138697 4966322 6645606 9875466 6433751 8517426 9211744 7516251 5633339 2065877 8690725 9172261 6929622 3143813 3642958 2773377 9081406 11711398 7874946 4643010 4916203 11753247 3953241 2398873 10683454 7225662 5918714 7396013 12678368 11295034 43849217 12785734 11977369 57972016 33255002 16589581 31669460 55539622 62909198 30805550 20008824 33114604 14421471 58008429 50034616 21066067 44087741 2118240 47037429 47754255 34538199 5909768 1058618 7248197 49420286 42876210 49697967 2073510 15833102 44467034 16404691 18172198 12515247 18435779 47572651 33180132 45371873 11552346 32364767 36575869 42738939 1876968 13829629 39063655 46273392 33845705 36064974 59729691 34432121 56775006 12408237 55448649 63020991 36823959 56131297 1870687 53252286 22587992 49980040 39719254 2346344 49328662 40973396 31936547 53348306 3474309 10694164 20229098 33732390 11896732 50114657 40733245 31274345 49636824 50144627 34406994 +AAINNGYDMDIK(Lys->Arg) MGYG000002492_00917;MGYG000002670_01219;MGYG000000280_01601;MGYG000000076_01479;MGYG000004271_02656;MGYG000003215_00001;MGYG000000271_02750;MGYG000002517_02338;MGYG000000154_01456;MGYG000003694_02682;MGYG000000356_02284;MGYG000000489_01666;MGYG000002278_02228 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 0.46153846153846156 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 0.5384615384615384 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00917 0.07692307692307693 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 2136928 0 1299459 3393383 1683625 1738053 0 2017390 2173749 3508422 937344 1528782 1549348 1599664 2580105 1080954 2823269 0 2620417 2261758 3296971 1992631 0 976257 2853971 2013012 0 0 0 1865568 0 0 987372 1809069 1947727 1778284 2470968 1059712 621895 0 0 375366 350578 423600 0 321444 395088 502743 343341 156035 427588 474547 0 537617 904285 0 311278 271770 294427 0 0 613764 495733 0 0 0 0 738683 0 0 0 452613 0 276566 0 0 179088 0 338502 336425 0 238754 0 393780 0 0 0 0 0 0 0 399061 0 0 0 0 765409 0 0 285606 394402 0 0 0 0 380085 0 0 0 404819 461837 0 501126 236886 0 0 0 256522 0 385533 0 193837 0 0 0 0 324604 0 0 0 248618 0 0 0 0 0 0 0 466607 353662 0 0 0 0 0 0 267544 0 389518 0 0 0 0 0 0 0 0 0 0 0 0 0 0 285214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAINQASDVAALDNVR MGYG000002477_03370;MGYG000002535_02256;MGYG000002534_02305;MGYG000002494_00955 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,3XNIZ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily 1.0 pheS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 1.0 6.1.1.20 1.0 ko:K01889 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iSSON_1240.SSON_1444,iYL1228.KPN_02176 1.0 Phe_tRNA-synt_N,tRNA-synt_2d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002477_03370 0.25 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01889:FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 669403 0 0 772845 0 0 0 702928 0 0 0 651056 0 0 696504 0 1007406 0 836248 774014 0 824587 0 0 0 0 1091738 763263 0 0 621587 0 0 0 0 444030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAINQASDVAALDNVRVEYLGK MGYG000002477_03370;MGYG000002535_02256;MGYG000002534_02305;MGYG000002494_00955 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,3XNIZ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily 1.0 pheS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 1.0 6.1.1.20 1.0 ko:K01889 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iSSON_1240.SSON_1444,iYL1228.KPN_02176 1.0 Phe_tRNA-synt_N,tRNA-synt_2d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002477_03370 0.25 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01889:FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 766896 0 0 850762 0 0 0 0 0 0 0 0 0 0 842835 0 646138 0 0 1180657 0 825731 0 0 0 0 0 0 0 0 514440 0 0 0 0 350891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAINQMELNPNFNAGR MGYG000001410_01243 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__Sutterella wadsworthensis_A|m__MGYG000001410 1.0 COG1446@1|root,COG1446@2|Bacteria,1MWFC@1224|Proteobacteria,2VIYM@28216|Betaproteobacteria 1.0 28216|Betaproteobacteria 1.0 E 1.0 PFAM peptidase T2 asparaginase 2 1.0 iaaA 1.0 - 1.0 3.4.19.5,3.5.1.1 1.0 ko:K01424,ko:K13051 1.0 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 1.0 - 1.0 R00485 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 Asparaginase_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001410_01243 1.0 beta-aspartyl-peptidase. | asparaginase. L-asparagine amidohydrolase. Other isopeptide bonds, e.g. gamma-glutamyl and beta-alanyl, are not hydrolyzed.-!-Formerly EC 3.4.13.10. Cleavage of a beta-linked Asp residue from the N-terminus of a polypeptide. | H2O + L-asparagine = L-aspartate + NH4(+). 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Cyanoamino acid metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01424:E3.5.1.1, ansA, ansB; L-asparaginase [EC:3.5.1.1]|K13051:ASRGL1, iaaA; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1004950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1176248 0 0 0 +AAINVGK MGYG000001652_01307 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__V9D3004|s__V9D3004 sp002349525|m__MGYG000001652 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,27J0E@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 PEP-utilising enzyme, TIM barrel domain 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001652_01307 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 905293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1361380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372686 0 0 0 0 359237 0 0 350744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAINVK MGYG000000142_02834;MGYG000000463_01481;MGYG000000140_01464;MGYG000000417_00539;MGYG000000031_02405;MGYG000001698_00702;MGYG000000249_01089;MGYG000000398_01662;MGYG000000036_01410;MGYG000001757_01805;MGYG000000728_00587;MGYG000003307_01519;MGYG000001531_01607;MGYG000003581_02331;MGYG000001315_01921;MGYG000000194_03193;MGYG000002963_02777;MGYG000004296_00104;MGYG000000242_00224;MGYG000002945_01502;MGYG000000133_02955;MGYG000000201_02673;MGYG000000196_03104;MGYG000002279_01986;MGYG000004558_03187;MGYG000000251_01169;MGYG000000153_02081;MGYG000004810_00381;MGYG000003821_02000;MGYG000000383_01314;MGYG000000164_00358;MGYG000000159_02392;MGYG000000404_01435;MGYG000002966_02744;MGYG000000187_00493;MGYG000002492_01692;MGYG000004547_00698;MGYG000004845_02015;MGYG000000806_02014;MGYG000000089_02490;MGYG000000243_00081;MGYG000000002_01928;MGYG000001310_01399;MGYG000003432_00750 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.2727272727272727 186801|Clostridia 0.9545454545454546 G 0.9545454545454546 Belongs to the PEP-utilizing enzyme family 0.7045454545454546 ppdK 0.9545454545454546 - 1.0 2.7.9.1 0.9545454545454546 ko:K01006 0.9545454545454546 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.9545454545454546 M00169,M00171,M00172,M00173 0.9545454545454546 R00206 0.9545454545454546 RC00002,RC00015 0.9545454545454546 ko00000,ko00001,ko00002,ko01000 0.9545454545454546 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9545454545454546 - 1.0 - 1.0 - 1.0 GT1 0.9318181818181818 MGYG000000142_02834 0.022727272727272728 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.9545454545454546 0.9545454545454546 0.9545454545454546 0.9545454545454546 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 0.9545454545454546 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 0.9545454545454546 none 1.0 4550892 3644932 2970383 0 0 3376167 2651117 3466423 3629126 3937613 6451524 0 7046735 3453603 4782694 5262521 3404603 0 3051121 0 6218367 7134221 6630208 2927793 0 3430161 4300537 0 3358750 2901544 2799897 2892422 3819749 4913974 5685927 3138595 3873859 5253256 3025217 3810703 3239929 3871469 4448048 0 4889534 4627525 2207225 2000835 4223160 3485644 4904925 2207370 2707591 2856936 0 5696033 3092202 4759448 2323913 1469005 4873646 0 3101823 3445394 3737063 11458844 0 2924249 7381579 3283963 4132086 5966352 5736834 5296223 4787829 7715232 3514906 5639931 8861208 4501827 4874310 3220377 3937587 5053487 3518994 7297737 5029705 4182082 5248061 4514436 5880747 7602317 4485200 485227 7190161 0 0 8335873 5786127 6713024 7538373 5365769 5917922 11014010 5126228 4979391 0 10377045 10938764 5877995 5282945 6148725 0 7658344 4773634 0 0 0 0 781697 0 2758546 4060100 1372729 833890 1426257 0 3449123 3223084 0 2147021 1424868 2193001 4043315 1584762 1958109 534136 1568514 0 2320752 2630838 0 0 4172405 2533051 858841 0 1733393 0 2795521 7377664 2835567 0 5063787 0 7510162 3365953 2565046 8323630 4189691 0 0 7495160 0 1611799 0 6525246 2293853 0 2144200 2864955 0 0 4345497 3255472 4598491 7237630 0 9510204 3003058 6674563 3142597 0 675258 0 4795090 6752443 0 0 8442165 +AAINVQK MGYG000001687_00537;MGYG000000271_00388;MGYG000004735_00207;MGYG000004487_00114;MGYG000000145_01088;MGYG000000245_03386;MGYG000001688_03814;MGYG000001619_00896;MGYG000000258_01879;MGYG000002926_01683;MGYG000002143_00035;MGYG000002707_01357;MGYG000003979_01382;MGYG000003074_00103;MGYG000004271_01396;MGYG000000152_05136;MGYG000003504_01005;MGYG000000099_03199;MGYG000002517_01243;MGYG000002025_01833;MGYG000004475_00310;MGYG000002720_01364;MGYG000003013_00135;MGYG000002794_01254;MGYG000000268_00698;MGYG000001496_03326;MGYG000001733_00637;MGYG000000175_01356;MGYG000000076_02377;MGYG000000472_00116;MGYG000001607_01964;MGYG000000387_01345 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.34375 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8125 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 0.96875 MGYG000001687_00537 0.03125 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 6403354 0 0 0 0 0 4703509 4131131 5464393 0 4293751 5781688 0 0 0 0 0 5117755 0 0 8968605 4533721 4637458 3483444 0 6352457 6342463 0 3678549 0 1443351 1963045 0 8554917 6861533 5912718 7933211 2099418 1965078 1655805 126974 1916738 0 1201633 1184356 2218634 2393675 1682037 1540330 1304161 1525468 2001659 1678778 1371377 849307 1813057 847937 2385489 1035671 0 2342763 1031213 1721245 2232852 2167407 0 3094534 1090568 1448134 1546756 1824024 2870141 2533420 2617241 2116983 2005229 4919993 0 2602625 5456580 0 3440130 4876314 8110572 7255512 7351398 3294308 4509314 5217989 9034569 8699962 4853320 6685851 0 7475114 0 0 4027586 6050237 3581051 0 9134247 8664249 6280381 7516860 0 0 3725811 4973357 8161628 0 7525412 6043507 0 21663011 3965991 6488831 22525305 0 9398824 8770374 0 16043890 13470059 9758151 11574066 7543457 20136656 30066608 7854163 0 3167980 0 17720810 5160276 0 1087478 5824717 0 13791237 15845268 5018762 6710296 20031141 6055993 5638625 9157681 16584102 0 15366772 28139023 6771167 0 0 0 0 0 17896072 22489572 0 0 0 0 0 8478468 0 0 0 24023964 0 0 0 0 9332225 0 0 29383189 0 0 0 13400003 0 0 0 0 0 19860486 0 30917968 0 +AAINVQKK MGYG000002720_01364;MGYG000000131_01163;MGYG000003013_00135;MGYG000000271_00388;MGYG000002794_01254;MGYG000000245_03386;MGYG000004475_00310;MGYG000001733_00637;MGYG000002143_00035;MGYG000000076_02377;MGYG000002707_01357 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.5454545454545454 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 0.9090909090909091 MGYG000002720_01364 0.09090909090909091 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 647663 0 0 0 0 0 636136 0 0 0 0 539806 0 0 0 0 0 0 0 381029 593020 0 0 0 454142 386128 697462 0 0 739116 0 0 0 677699 0 598536 606425 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241270 0 0 0 0 0 120820 0 0 0 0 108850 0 0 0 0 0 0 0 472397 435376 0 0 0 410402 419708 476298 0 0 105657 0 0 0 373978 0 382845 525508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 298735 0 0 0 0 1244656 0 0 0 0 0 0 0 281334 216563 0 0 0 250040 250113 653873 0 0 603999 0 0 0 559467 0 243052 788110 0 +AAIPE(Glu->Gly)LGDNVQFHDLATAAR MGYG000000164_02794 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0191@1|root,COG0191@2|Bacteria,1TRS4@1239|Firmicutes,3VSU5@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 H 1.0 Fructose-bisphosphate aldolase class-II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_02794 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1060569 0 0 837251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269831 0 0 151466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIPEGAR MGYG000000084_01831 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger formicilis|m__MGYG000000084 1.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3WGWM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Glucose-1-phosphate adenylyltransferase, GlgD subunit 1.0 glgD 1.0 - 1.0 2.7.7.27 1.0 ko:K00975 1.0 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 1.0 M00565 1.0 R00948 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Hexapep,NTP_transferase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000084_01831 1.0 glucose-1-phosphate adenylyltransferase. ADP-glucose synthase. - alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate. 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biofilm formation - Escherichia coli 1.0 K00975:glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1330508 0 0 0 0 0 0 0 0 0 1371786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1579387 0 0 0 0 0 1237964 0 0 0 0 1670805 0 0 0 0 1722628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802435 0 0 0 0 0 678599 0 0 0 0 855749 0 0 0 0 611931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1334080 0 0 0 0 0 1540492 0 0 0 0 427053 0 0 0 0 2131147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIPTIK MGYG000000196_04506;MGYG000000301_01011;MGYG000000003_00285;MGYG000000258_00429;MGYG000000170_00153;MGYG000000154_00118;MGYG000000262_01196;MGYG000000074_02205;MGYG000000414_01789;MGYG000000044_00323;MGYG000000142_01978;MGYG000002528_00366;MGYG000002549_02739;MGYG000002438_03839;MGYG000002455_00199;MGYG000002395_00974;MGYG000003279_01634;MGYG000001683_01828;MGYG000001338_02546;MGYG000000271_03251;MGYG000000084_00216;MGYG000003452_00954;MGYG000000133_02282;MGYG000004735_01945;MGYG000004876_02584;MGYG000002098_01090;MGYG000001489_04176 domain d__Bacteria 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,22UY0@171550|Rikenellaceae 0.18518518518518517 976|Bacteroidetes 0.4444444444444444 F 0.5925925925925926 Belongs to the phosphoglycerate kinase family 0.5925925925925926 pgk 1.0 - 0.9259259259259259 2.7.2.3,5.3.1.1 0.5555555555555556 ko:K00927,ko:K01803 0.5555555555555556 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.5555555555555556 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 0.5555555555555556 RC00002,RC00043,RC00423 0.5555555555555556 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 0.5555555555555556 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04506 0.037037037037037035 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 0.5555555555555556 0.5555555555555556 0.5555555555555556 0.5555555555555556 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.5555555555555556 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 0.5555555555555556 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3098155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2428113 0 0 0 0 0 0 2883751 0 0 0 0 0 0 0 0 0 0 0 0 0 3168528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2767537 0 0 0 +AAIPTIR MGYG000001302.1_01773 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,22UY0@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TPR_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_01773 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 117231 0 0 0 0 181107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94443 0 0 0 0 0 0 0 0 0 134740 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 595508 0 0 0 0 556341 0 0 0 0 352815 0 0 0 0 0 0 0 0 0 0 +AAIQAEIDANNAAVK MGYG000002143_00635 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900545585|m__MGYG000002143 1.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,2N67Z@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Seryl-tRNA synthetase N-terminal domain 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002143_00635 1.0 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01875:SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIQELR MGYG000001783_01160 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900551065|m__MGYG000001783 1.0 COG0542@1|root,COG0542@2|Bacteria,4NGEM@976|Bacteroidetes,2FM5N@200643|Bacteroidia,4AKZF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE 1.0 clpB 1.0 - 1.0 - 1.0 ko:K03695 1.0 ko04213,map04213 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03110 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_2,ClpB_D2-small,Clp_N 1.0 - 1.0 - 1.0 - 1.0 GT4 1.0 MGYG000001783_01160 1.0 - - - - 1.0 1.0 1.0 1.0 Longevity regulating pathway - multiple species 1.0 K03695:clpB; ATP-dependent Clp protease ATP-binding subunit ClpB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226557 0 0 0 0 525477 0 0 0 739519 285311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1354397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 398509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534333 0 0 0 0 944364 0 0 0 317291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 812699 0 0 0 0 0 0 0 0 924474 0 0 0 0 0 0 0 0 0 0 0 +AAIQIK MGYG000001346_00290 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG2115@1|root,COG2115@2|Bacteria,4NEBQ@976|Bacteroidetes,2FN9P@200643|Bacteroidia,4AN2N@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 xylA 1.0 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 1.0 5.3.1.5 1.0 ko:K01805 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 - 1.0 R00878,R01432 1.0 RC00376,RC00516 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_00290 1.0 xylose isomerase. D-xylose ketol-isomerase. Contains two divalent metal ions, preferably magnesium, located at different metal-binding sites within the active site.-!-The enzyme catalyzes the interconversion of aldose and ketose sugars with broad substrate specificity.-!-The enzyme binds the closed form of its sugar substrate (in the case of xylose and glucose, only the alpha anomer) and catalyzes ring opening to generate a form of open-chain conformation that is coordinated to one of the metal sites.-!-Isomerization proceeds via a hydride-shift mechanism. alpha-D-xylose = alpha-D-xylulofuranose. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K01805:xylA; xylose isomerase [EC:5.3.1.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIRIPFFER MGYG000000271_00922;MGYG000004271_01649 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG2268@1|root,COG2268@2|Bacteria,1TQDT@1239|Firmicutes,247MK@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 SPFH Band 7 PHB domain protein 1.0 - 1.0 - 1.0 - 1.0 ko:K07192 1.0 ko04910,map04910 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03036,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Band_7,Flot 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00922 0.5 - - - - 1.0 1.0 1.0 1.0 Insulin signaling pathway 1.0 K07192:FLOT; flotillin 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIRPFVLDANEQAGANFA(Ala->Pro)TLK MGYG000001306_03824 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola coprocola|m__MGYG000001306 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,4NF4F@976|Bacteroidetes,2FKZU@200643|Bacteroidia,4AM1C@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_13,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001306_03824 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 817778 0 0 0 0 1186484 0 0 0 0 856509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAISAG(Gly->Xle)LK MGYG000002506_02514 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,1RSHX@1236|Gammaproteobacteria,3XMZG@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 I 1.0 Methylmalonyl-CoA mutase 1.0 scpA 1.0 GO:0003674,GO:0003824,GO:0004494,GO:0005488,GO:0008144,GO:0016853,GO:0016866,GO:0019842,GO:0031419,GO:0036094,GO:0046906,GO:0048037,GO:0097159,GO:1901363 1.0 5.4.99.2 1.0 ko:K01847,ko:K01848 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00375,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECO111_1330.ECO111_3653,iECO26_1355.ECO26_4004 1.0 B12-binding,MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02514 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2]|K01848:E5.4.99.2A, mcmA1; methylmalonyl-CoA mutase, N-terminal domain [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAISEINK MGYG000000164_02895 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,27PVR@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_02895 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02968:RP-S20, rpsT; small subunit ribosomal protein S20 1.0 none 1.0 0 0 0 0 0 0 5088363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4175749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1468311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1610458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1718933 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 955965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1594096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1180460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 732783 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAISLAK MGYG000001378_03520;MGYG000001345_01966 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0141@1|root,COG0141@2|Bacteria,4NFPZ@976|Bacteroidetes,2FMY9@200643|Bacteroidia,4AM1G@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine 1.0 hisD 1.0 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.1.1.23 1.0 ko:K00013 1.0 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 1.0 M00026 1.0 R01158,R01163,R03012 1.0 RC00099,RC00242,RC00463 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2,DUF559,Histidinol_dh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_03520 0.5 histidinol dehydrogenase. - Also oxidizes L-histidinal.-!-The Neurospora enzyme also catalyzes the reactions of EC 3.5.4.19 and EC 3.6.1.31. H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH. 1.0 1.0 1.0 1.0 Histidine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00013:hisD; histidinol dehydrogenase [EC:1.1.1.23] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 553969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAISLDDKAPEITPTVYR MGYG000002494_02884 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3ZJCJ@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 F 1.0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 deoA 1.0 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 1.0 2.4.2.4 1.0 ko:K00758 1.0 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 1.0 - 1.0 R01570,R02484,R08222,R08230 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 1.0 Glycos_trans_3N,Glycos_transf_3,PYNP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02884 1.0 thymidine phosphorylase. pyrimidine phosphorylase. In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.-!-Formerly EC 2.4.2.23. phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Bladder cancer 1.0 K00758:deoA, TYMP; thymidine phosphorylase [EC:2.4.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 561199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1156176 0 770473 0 0 0 0 0 0 0 0 626593 0 0 0 0 424708 0 0 0 0 0 193032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 260405 0 0 0 0 0 0 0 0 121574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAISLDN(Deamidated)KAPEITPTVYR MGYG000003372_04094 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter|s__Citrobacter werkmanii|m__MGYG000003372 1.0 COG0213@1|root,COG0213@2|Bacteria,1MV3H@1224|Proteobacteria,1RPTG@1236|Gammaproteobacteria,3ZJCJ@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 F 1.0 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis 1.0 deoA 1.0 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009032,GO:0009116,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0033554,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072527,GO:1901135,GO:1901360,GO:1901564,GO:1901657 1.0 2.4.2.4 1.0 ko:K00758 1.0 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 1.0 - 1.0 R01570,R02484,R08222,R08230 1.0 RC00063 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iB21_1397.B21_04224,iEC042_1314.EC042_4879,iECBD_1354.ECBD_3638,iECB_1328.ECB_04258,iECD_1391.ECD_04258,iECH74115_1262.ECH74115_5897,iECIAI1_1343.ECIAI1_4605,iECIAI39_1322.ECIAI39_4914,iECSE_1348.ECSE_4657,iECSP_1301.ECSP_5465,iECUMN_1333.ECUMN_5006,iECW_1372.ECW_m4744,iEKO11_1354.EKO11_3932,iETEC_1333.ETEC_4738,iEcE24377_1341.EcE24377A_4981,iEcSMS35_1347.EcSMS35_4931,iEcolC_1368.EcolC_3674,iG2583_1286.G2583_5242,iSSON_1240.SSON_4533,iSbBS512_1146.SbBS512_E4929,iUMNK88_1353.UMNK88_5301,iWFL_1372.ECW_m4744,iYL1228.KPN_04838,iZ_1308.Z5984,ic_1306.c5466 1.0 Glycos_trans_3N,Glycos_transf_3,PYNP_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003372_04094 1.0 thymidine phosphorylase. pyrimidine phosphorylase. In some tissues also catalyzes deoxyribosyltransferase reactions of the type catalyzed by EC 2.4.2.6.-!-Formerly EC 2.4.2.23. phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Bladder cancer 1.0 K00758:deoA, TYMP; thymidine phosphorylase [EC:2.4.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1173856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAISSPLLETSIAGAR MGYG000003937_01659;MGYG000000573_01385;MGYG000003921_01788;MGYG000004700_01055;MGYG000001157_02513;MGYG000004732_00963;MGYG000001627_00389 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 - 0.8571428571428571 - 1.0 MGYG000003937_01659 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 911473 0 729203 0 0 0 0 0 645838 0 1055758 0 0 0 0 582396 0 0 0 0 1227446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 822840 0 0 0 0 708781 0 0 0 0 757526 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290451 0 0 0 0 0 192146 0 657426 0 0 0 0 420271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351912 0 279403 0 0 0 0 0 244103 0 1678036 0 0 0 0 1751044 0 0 0 0 1797461 0 0 0 0 0 0 0 0 0 0 +AAITAALIK MGYG000002395_00912;MGYG000003683_00404;MGYG000000756_00589;MGYG000003452_00999;MGYG000001490_01038;MGYG000002469_01207;MGYG000001292_01083 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CYVQ@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,Ribosomal_S2,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002395_00912 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 308774 332071 1049848 0 0 405490 0 0 0 608506 0 350807 1377571 315214 747543 1194106 0 281721 456460 564024 384024 367644 190918 0 534507 271226 236059 230833 387730 228153 0 157544 729641 314035 299436 0 138239 825357 1809913 1628297 2139394 0 0 2759272 0 0 0 1757660 0 901896 6660718 1228165 1448722 2939058 0 8159039 1093320 1808707 1014046 1591701 2777068 4854726 1500418 1281091 1682923 5021971 2303087 1298399 0 875317 1911690 2163053 2113434 0 1580785 3134079 1619190 1316454 1011093 0 0 489464 0 0 0 1231561 0 819727 917478 906779 1442482 1914845 0 409474 1234371 1711902 1158514 1254256 737384 414301 1304502 997725 1534156 1256331 964948 1312076 0 1155137 2215562 1492500 1727646 0 1016129 974237 380329 325437 267245 0 0 952892 0 0 0 319984 0 109194 494604 278454 519658 1023373 0 0 163077 423115 161483 1210205 2458443 1068031 553336 566788 278111 956420 577891 240571 0 653485 342928 817267 663160 0 292904 428331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAITAEVR MGYG000002506_02942;MGYG000002494_02450;MGYG000002323_00405 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,3XPK7@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02942 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 0 0 0 0 0 574495 0 0 0 534165 0 0 0 0 0 0 0 0 521050 0 0 525102 0 0 0 0 0 0 0 0 0 0 0 350924 0 0 0 0 0 0 0 0 0 1305874 728756 0 0 1277552 0 0 0 0 0 0 0 0 868650 0 0 1896798 0 1389975 0 0 0 0 0 0 0 0 0 860089 0 0 0 0 0 0 0 0 0 1699785 1283331 0 0 1508417 0 0 0 0 0 0 0 0 1236177 0 0 1408852 0 1611896 0 0 0 0 0 0 0 0 0 1416499 0 0 0 0 0 0 0 0 0 902569 1374620 0 0 1791178 0 0 0 0 0 0 0 0 1743952 0 0 615290 0 514582 0 0 0 0 0 0 0 0 0 964825 0 0 0 0 0 0 0 0 0 0 374474 0 0 590078 0 0 0 0 0 0 0 0 455257 0 0 335072 0 394642 0 0 0 0 0 0 0 0 0 498724 0 0 0 0 +AAITAVLAAR MGYG000002492_00344 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_00344 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 138149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 970061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 854364 0 0 0 0 872017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAITDAR MGYG000001313_00702;MGYG000001661_00104 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG3746@1|root,COG3746@2|Bacteria,4NK1Y@976|Bacteroidetes,2FKYR@200643|Bacteroidia,4AW00@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 ko:K07221 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.5.1 1.0 - 1.0 - 1.0 Porin_O_P 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_00702 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07221:oprO_P; phosphate-selective porin OprO and OprP 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4866930 2363994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAITHPVLSGPAYER MGYG000000074_02321;MGYG000002082_01295 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 F 1.0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02321 0.5 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00948:PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 1.0 none 1.0 357240 0 0 0 127557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366350 0 0 0 0 0 482777 0 0 0 298518 0 0 0 0 0 0 151682 0 308137 0 0 0 405696 0 0 0 0 0 0 0 0 0 0 0 0 0 410149 672653 0 0 0 0 0 534304 0 0 0 0 0 0 0 0 0 0 411326 0 498343 0 0 0 371505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 404562 0 0 0 0 0 535909 0 0 0 643472 0 0 0 0 0 0 313206 0 183536 0 0 0 498291 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 404176 0 0 0 0 0 0 0 0 1381804 0 0 0 1874248 0 0 0 0 0 0 0 0 0 0 0 0 0 1931862 2809922 0 0 0 0 0 1231609 0 0 0 1539191 0 0 0 0 0 0 1423921 0 +AAITIPAK MGYG000002281_03589;MGYG000000196_01829 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia,4ARQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_03589 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 2130842 2088596 1396575 2098456 1920958 1886527 2176429 1855910 1845172 2063433 1057628 1787015 1199310 2180882 1736726 1795134 2003064 640693 1668179 2016044 2269399 1246870 1109191 2353082 1553027 1953893 1943195 636347 3310275 1108799 2018207 2744506 1802194 2454598 2374773 1892668 2394386 1728983 2914708 2253653 2505890 2549416 2182056 0 2234628 2750553 2622906 2724538 2300394 0 1956161 2563502 0 2248113 2391904 0 2017488 2058668 2210055 2456685 390077 1708896 2357187 2308233 2416818 267464 2138790 2034858 1379603 2017061 2800249 3163738 2663366 2491176 2424459 0 732106 805815 820120 1040821 938256 949877 1234438 954137 1172422 681822 994985 612060 735997 1204477 1037080 774278 775152 1090888 707265 812094 734316 754717 942390 1112280 867201 836936 787112 294840 1057146 787326 1002598 703363 610046 937244 508737 1099943 956954 0 647986 142353 193078 982079 190705 333621 721220 747758 283075 173677 340503 566628 577088 148890 771865 193742 0 183552 835023 1026193 861658 430397 444897 271516 846220 794831 582372 455618 179262 188740 156169 902010 147069 1570247 683360 988068 840713 324147 1833769 1127536 1267784 2634503 1873271 1836013 2059396 2354583 2440902 2041918 1039797 1595875 1289643 1359402 1566682 999752 2085808 470570 1347760 2442237 1301780 1389319 380988 1484110 0 2978095 1408758 283975 2084281 2084196 0 1449617 783072 2573566 0 1342540 1944420 1477856 +AAITIPAKK MGYG000002281_03589;MGYG000000196_01829 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia,4ARQ9@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_03589 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 1461436 1568906 791070 1294274 1034049 1414951 1460970 997198 1012608 969715 497789 859675 997713 1583893 660475 1219424 1170002 0 895009 1443106 1349742 1177503 0 999321 801888 905023 1015108 0 1625874 848845 1050226 1852844 1189258 1809881 1168163 1030518 1610284 1341100 1849653 1564101 1914506 1359441 1196119 843366 888197 1105397 1517220 1517710 1241513 1142280 983535 1283968 951753 863523 1334955 0 671827 800149 868193 882437 0 935365 912811 1066949 1126327 0 1214724 868459 956981 1564528 1737957 2094941 874439 1473231 1466665 1292288 288182 488544 446174 436786 554013 505885 624689 205973 646196 315611 562562 191312 303125 410741 343123 469842 241487 0 277291 388185 343413 468126 0 404677 365635 160742 388356 0 581306 320877 591308 267673 252525 423282 125731 543795 496305 501482 408120 387876 185159 201099 320044 300065 528188 536916 433297 455356 306659 428721 60706 317927 358055 388937 269392 0 377170 384442 152909 183057 0 184998 446396 642300 353384 0 447932 179320 274923 525075 315553 588358 463250 490846 471958 221790 880133 678174 0 1685299 927211 1223249 1505886 1618198 1638283 1291536 712713 1056560 1351622 946360 1038012 706813 1081532 0 885264 1298779 1025405 1083353 0 820174 0 1887822 914290 0 786794 1518157 0 908166 0 2112758 1173096 1752577 1368145 988154 +AAITPVVNATV(Val->Xle)DR MGYG000004487_00297 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900547745|m__MGYG000004487 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004487_00297 1.0 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K01844:kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1766673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2321850 0 0 0 0 0 0 2162254 2007629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAITPVVNATVD(Methyl[D](Asp->Glu)R MGYG000004487_00297 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900547745|m__MGYG000004487 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004487_00297 1.0 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K01844:kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1537058 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1787200 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAITPVVNATVER MGYG000002794_00763;MGYG000002143_01959;MGYG000001733_00672;MGYG000004196_01673;MGYG000004475_00752 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_00763 0.2 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K01844:kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3] 1.0 none 1.0 0 0 232014 311519 0 480556 0 539720 342977 0 0 0 0 396481 0 0 604113 0 0 0 0 0 0 189016 387047 0 408007 0 0 0 0 412705 189124 327924 357542 0 0 254480 0 0 0 450135 0 131050 0 206891 0 0 0 0 0 121827 0 0 674176 0 0 0 0 242864 0 469577 0 0 0 0 0 0 0 160724 0 446161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1891961 0 1774606 0 2346905 2017800 0 0 0 0 1667784 0 0 1980028 0 0 0 0 1483482 0 1306959 2319597 0 2027226 0 0 0 0 1552458 1554871 2159488 1879622 0 0 1383781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAITSLGHVTEGR MGYG000000258_01692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Ruminococcus_E|s__Ruminococcus_E bromii_B|m__MGYG000000258 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000258_01692 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194053 0 0 309527 0 0 0 352603 0 0 0 279196 0 0 0 0 0 0 0 382510 0 0 0 0 0 0 0 0 0 0 299369 0 0 0 0 349627 0 0 401974 443112 0 348694 1073217 468657 0 906593 0 0 0 883600 0 0 0 1846971 0 0 0 284569 1506055 1136875 0 0 0 1216898 0 0 0 0 0 0 0 1211870 0 780233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAITTVLAK MGYG000000042_01421;MGYG000000138_00665;MGYG000000053_00908;MGYG000000412_01546;MGYG000004006_00433;MGYG000000074_01773;MGYG000001806_01406;MGYG000002535_04656;MGYG000002515_03208;MGYG000000273_00431;MGYG000004763_01689;MGYG000003184_03610;MGYG000001302.1_00073;MGYG000003363_01661;MGYG000003202_00129;MGYG000002281_02290;MGYG000002506_02966;MGYG000003546_00955;MGYG000002470_01245;MGYG000002514_02415;MGYG000000013_02251;MGYG000003394_01668;MGYG000002455_03884;MGYG000002507_00346;MGYG000002839_00878;MGYG000002515_03657;MGYG000001655_02933;MGYG000000044_01721;MGYG000004756_01173;MGYG000000196_03974;MGYG000002905_00001;MGYG000001661_02666;MGYG000002514_01953;MGYG000001789_00154;MGYG000000054_03933;MGYG000000236_01807;MGYG000003701_03123;MGYG000000098_02017;MGYG000002291_02272;MGYG000000170_00073;MGYG000001415_02515;MGYG000002438_02321;MGYG000002556_01332;MGYG000004658_01205;MGYG000001346_01533;MGYG000000243_01988;MGYG000001780_03476;MGYG000001562_01075;MGYG000002540_03367;MGYG000000254_02569;MGYG000003279_00951;MGYG000001412_04734;MGYG000000414_00662;MGYG000001712_00119;MGYG000002418_00753;MGYG000000117_01463;MGYG000003535_00219;MGYG000002506_03686;MGYG000000673_00997 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,22W1B@171551|Porphyromonadaceae 0.288135593220339 976|Bacteroidetes 0.7457627118644068 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 0.8305084745762712 tuf 1.0 - 0.9491525423728814 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 0.9491525423728814 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01421 0.01694915254237288 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 9084077 8917034 14619434 7128048 13438344 10643556 9494797 8942673 8814180 9397243 10201426 9176616 12083717 10828647 9440204 11412407 9841059 6877477 10740246 9553647 8804446 9027375 8267300 11220901 9527844 9898371 9106210 7559150 8316098 8952059 13765877 13559793 13721076 9380252 10251295 9873939 10848315 14167544 4216893 2601797 3930416 3183086 4195994 3313524 2898251 4055974 4543105 4417347 3897904 3289128 4260555 3663036 3791911 3299732 3942724 2045850 4846479 4041760 3840488 4005958 3311775 2318379 3907338 4065552 3170770 2529634 3099606 3799868 1598324 3855450 4001719 3060659 3922330 3264567 4120023 3329196 4119308 3532043 2512287 3893685 7376202 5944528 5445637 4256629 6497859 4031093 7000801 3373196 6262909 5184515 4000185 5071363 4403994 3864297 4349296 5139616 4968134 3717510 2236214 5936315 4573270 4053526 3746081 1566685 4581378 4921424 5524542 3267548 3596770 3032304 3983281 6033506 4222966 5472425 3769574 2499149 2752395 2553803 2997224 3498021 4035427 3114243 2992068 3321153 3112999 3710996 2754973 2835150 2897065 3304516 2871101 600532 2922729 3335063 5040553 1884076 207262 1885175 3209516 3162772 3961864 0 2781953 3495357 2497264 3357110 3007023 3355838 3665275 3945045 3622727 1977277 2366198 2549184 1726663 2393423 4405997 2558503 1505595 2523407 2072673 2022849 1813705 1919230 5309004 1258777 1674207 2695854 2155761 3434304 2816023 3176724 2405729 2663089 2854433 2075440 1573242 1463244 1723883 2710033 2450977 3977395 2307019 4108308 1428298 1697307 2069559 1453599 1820610 1716242 +AAITTVLAKK MGYG000000196_03974;MGYG000000236_01807;MGYG000000044_01721;MGYG000004763_01689;MGYG000001302.1_00073;MGYG000000243_01988;MGYG000000013_02251;MGYG000000170_00073;MGYG000003202_00129 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0050@1|root,COG0050@2|Bacteria,4NEWS@976|Bacteroidetes,2FKZA@200643|Bacteroidia,4AKAJ@815|Bacteroidaceae 0.4444444444444444 976|Bacteroidetes 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_03974 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAITTVLGK MGYG000000323_00619;MGYG000001313_00097;MGYG000001503_00139 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli,4AZAI@81852|Enterococcaceae 0.3333333333333333 976|Bacteroidetes 0.6666666666666666 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 0.6666666666666666 - 1.0 ko:K02358 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000323_00619 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 0.6666666666666666 K02358:tuf, TUFM; elongation factor Tu 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140058 0 262738 0 0 0 0 0 1241824 0 0 0 927381 0 0 0 0 0 0 0 0 0 0 0 0 0 667967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 998018 0 0 1308142 1342151 904962 1235960 0 0 0 803351 0 0 0 0 0 0 990347 1057999 0 0 971149 0 0 0 0 0 0 0 0 0 0 918130 1099557 0 0 0 0 0 0 0 0 0 441010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 501143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIVAAC(Carbamidomethyl)QAK MGYG000003937_01474 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3WGMD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01474 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 3117979 3104265 2664575 2451578 3181347 3872306 0 3133318 2687151 2985546 3019782 3335455 3136719 2813644 3112381 3417083 2557771 6260744 0 4433306 3427140 3580596 4224238 1647012 0 2537414 2650835 4477688 2661931 2664882 1433159 2417576 2110149 2551085 3103560 2307555 2295805 2475168 573291 571446 494470 707951 582132 447427 0 676013 492935 375160 578325 639825 236122 544656 282328 301665 486650 623859 0 695255 278988 426103 833995 381116 0 471776 566966 0 409130 333166 634972 575921 533889 537009 390037 558524 754768 605716 385308 630905 504646 592959 0 602864 0 0 501598 0 0 348176 450691 0 0 0 138704 544026 0 416021 0 668543 177729 483624 0 206812 359259 1471231 611579 485095 489989 859042 0 162109 204622 322196 0 403809 542082 660188 617064 791123 860380 690443 0 576044 315719 689231 615152 1126892 632466 585927 454627 309412 371055 528776 0 463712 0 850302 115043 581510 0 0 551318 584794 0 524838 615824 914239 648490 260376 0 335625 358153 571401 0 127051 161745 0 0 227304 0 236515 246072 189780 182437 0 0 167778 287218 141369 167989 759990 0 0 375597 0 1096874 209655 0 0 0 777919 165150 0 101260 292004 0 97167 167298 0 227164 143346 +AAIVHGLK MGYG000003486_01280 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-95|s__CAG-95 sp000436115|m__MGYG000003486 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,268PI@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003486_01280 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2942647 0 0 1966820 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2870727 0 0 0 3192714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3050255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIVIAVK MGYG000002274_02929;MGYG000000195_00114 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3WG8A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Participates in both transcription termination and antitermination 1.0 nusA 1.0 - 1.0 - 1.0 ko:K02600 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009,ko03021 1.0 - 1.0 - 1.0 - 1.0 KH_5,NusA_N,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_02929 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02600:nusA; transcription termination/antitermination protein NusA 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492286 0 0 0 0 609494 0 0 0 0 394947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428718 0 0 0 0 310643 0 0 0 0 328458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 791942 0 0 0 0 749166 0 0 0 0 664536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257495 0 0 0 0 176200 0 0 0 0 320563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663644 0 0 0 0 738685 0 0 0 0 850315 0 0 0 0 0 0 0 0 0 0 +AAIWIEANVK MGYG000002506_01952;MGYG000002494_03988 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2837@1|root,COG2837@2|Bacteria,1MWDD@1224|Proteobacteria,1RMZJ@1236|Gammaproteobacteria,3XM48@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 P 1.0 peroxidase activity 1.0 yfeX 1.0 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020037,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1990748 1.0 - 1.0 ko:K07223 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Dyp_perox 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_01952 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07223:yfeX; porphyrinogen peroxidase [EC:1.11.1.-] 1.0 none 1.0 0 0 0 0 0 210639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 393979 0 353437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 562641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 846332 0 642903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146021 0 349717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147031 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 197586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIYGHDANWGR MGYG000002517_01106;MGYG000004271_00865;MGYG000000133_01203;MGYG000000301_00744 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia 0.5 186801|Clostridia 1.0 E 1.0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate 1.0 argJ 1.0 - 1.0 2.3.1.1,2.3.1.35 1.0 ko:K00620 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028 1.0 R00259,R02282 1.0 RC00004,RC00064 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ArgJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01106 0.25 amino-acid N-acetyltransferase. | glutamate N-acetyltransferase. N-acetylglutamate synthase. | ornithine transacetylase. Also acts with L-aspartate and, more slowly, with some other amino acids. | Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity. acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate. | L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L- glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00620:argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] 1.0 none 1.0 779323 668388 0 0 0 819023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 464666 0 403074 0 766631 0 0 0 0 509745 0 0 0 0 0 589121 0 256918 472429 0 0 0 199738 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 234276 0 247737 0 0 0 0 774080 0 0 0 0 0 232623 0 335413 459864 0 0 0 163117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447296 0 289221 0 287034 0 0 0 0 272883 0 0 0 0 0 479130 0 953387 485845 0 0 0 300313 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402921 0 290653 0 1352649 0 0 0 0 430465 0 0 0 0 0 1216496 0 1491329 2411799 0 0 0 1358218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1827358 0 1476316 0 1336972 0 0 0 0 2384747 0 0 0 0 0 1989700 0 +AAIYGSSSSDYALGLK MGYG000001421_00850 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__Dielma|s__Dielma fastidiosa|m__MGYG000001421 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 PFAM Extracellular ligand-binding receptor 1.0 - 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Peripla_BP_6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001421_00850 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 1.0 K01999:livK; branched-chain amino acid transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1109597 0 0 0 0 0 0 0 0 +AAIYHR MGYG000000074_01490 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0612@1|root,COG0612@2|Bacteria,4NDXM@976|Bacteroidetes,2FNQC@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Belongs to the peptidase M16 family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 M16C_assoc,Peptidase_M16,Peptidase_M16_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01490 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIYNGLQVK MGYG000000105_02450;MGYG000003681_00109;MGYG000000236_01485;MGYG000000098_00605 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0205@1|root,COG0205@2|Bacteria,4NF8F@976|Bacteroidetes,2FMPI@200643|Bacteroidia,4AP54@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis 1.0 pfkA 1.0 - 1.0 2.7.1.11 1.0 ko:K00850 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 1.0 M00001,M00345 1.0 R00756,R03236,R03237,R03238,R03239,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000105_02450 0.25 6-phosphofructokinase. phosphohexokinase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|AMPK signaling pathway|Central carbon metabolism in cancer 1.0 K00850:pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269348 0 0 0 0 0 0 0 423329 0 0 0 0 0 0 0 408174 0 217427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 347614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 571698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 558954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225887 0 452286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIYNLATGTVK MGYG000003899_01066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900539945|m__MGYG000003899 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000003899_01066 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 3784396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5181048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3766846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6586528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1333244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIYNLGFGTAK MGYG000001300_01291 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000001300_01291 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 341401 0 433536 300460 0 0 0 0 0 0 0 0 332875 522055 0 577397 222797 0 260383 0 181877 0 370558 0 0 0 0 0 0 0 0 0 0 354289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 483552 0 1524038 0 0 1782031 2017832 2504377 2052779 0 0 0 0 0 0 0 0 2611560 1889015 0 3044753 2355282 0 2381075 0 1588250 0 1944242 0 0 0 0 0 0 0 0 0 0 2060485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAIYSGEK MGYG000001780_00304;MGYG000004876_01447;MGYG000002478_02197 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 MGYG000001780_00304 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 660131 0 478000 986828 980794 875553 1074321 0 760459 0 925276 716781 0 890073 674077 1706197 828695 1102083 447585 988631 769559 1078319 1021119 1110913 637501 727896 0 848747 937475 0 940735 1234123 398712 369326 839976 1080544 777948 696419 1255218 0 1080317 1256933 1066154 881174 727393 0 752980 0 1056636 938444 0 1163748 766133 1672470 818068 0 905034 798263 881568 949321 1531469 695895 816688 951613 0 1333946 867673 0 1393345 896513 883960 866442 1257674 815451 1047561 669545 821217 0 559305 676141 1112505 818258 830321 0 909424 0 665992 728504 0 721264 705415 565095 921939 1075879 504037 596622 722075 597882 1555334 723379 697491 719541 0 905926 928875 0 933367 539910 265225 564592 1198314 908593 750781 757244 399446 0 507826 440174 320241 444655 386062 0 484237 0 365940 1214814 0 309555 147843 315036 519915 676181 256900 300926 201087 466113 224539 335880 319977 179790 0 1011390 321627 0 888405 480584 606313 273716 325719 622468 288746 289768 1668091 0 1083778 1195379 2391892 1314302 1319288 0 1492912 0 1015372 1060967 0 1252365 1475221 1987782 1274950 3260284 1177112 1922734 1311496 1535454 3802287 1697063 1934207 1819414 0 2237926 1379256 0 1683110 1583345 1196119 1983025 1520506 1698856 1682002 1281763 +AAIYSGEKGYEELC(Carbamidomethyl)K MGYG000002478_02197 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0673@1|root,COG0673@2|Bacteria,4NF3G@976|Bacteroidetes,2FN3V@200643|Bacteroidia,4AKSD@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Oxidoreductase NAD-binding domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 GFO_IDH_MocA 1.0 - 1.0 GH109 1.0 GH109 1.0 GH109 1.0 MGYG000002478_02197 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 425567 0 0 0 305716 492576 0 0 0 0 0 0 0 0 0 892014 0 0 0 0 0 326460 0 592429 0 591717 0 0 192811 0 620884 576509 0 255104 0 0 294131 0 298930 0 0 0 481777 280037 0 0 0 0 0 0 0 0 0 883589 0 0 0 0 0 213650 0 195349 0 279782 0 0 456856 0 593022 542287 0 278396 0 0 301007 0 393552 0 0 0 474825 420015 0 0 0 0 0 0 0 0 0 480447 0 0 0 0 0 355463 0 283905 0 231947 0 0 355653 0 543218 193976 0 222328 0 0 305607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174127 0 0 0 0 0 0 0 0 0 0 0 0 704970 0 0 0 1431741 1005162 0 0 0 0 0 0 0 0 0 932290 0 0 0 0 0 627386 0 2398386 0 736029 0 0 746710 0 672755 1854944 0 625461 0 0 993285 0 +AAK(Lys->Ala)PAAPK MGYG000000074_01933 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0203@1|root,COG0203@2|Bacteria,4NNW0@976|Bacteroidetes,2FNPH@200643|Bacteroidia,22UFD@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Ribosomal protein L17 1.0 rplQ 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 1.0 - 1.0 ko:K02879 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Ribosomal_L17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01933 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02879:RP-L17, MRPL17, rplQ; large subunit ribosomal protein L17 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 140459 0 82540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134226 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8211582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKAAEAEAAR MGYG000004681_01708;MGYG000002961_00396 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0254@1|root,COG0254@2|Bacteria,2HUWQ@201174|Actinobacteria,4CVW5@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Binds the 23S rRNA 1.0 rpmE 1.0 - 1.0 - 1.0 ko:K02909 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L31 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004681_01708 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02909:RP-L31, rpmE; large subunit ribosomal protein L31 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKAD(Methyl[D](Asp->Glu)GITGEVLLQNLEC(Carbamidomethyl)R MGYG000002293_00480 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,2FMRC@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00480 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 503762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKADSIEVR MGYG000004158_00690 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister invisus|m__MGYG000004158 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TSVA@1239|Firmicutes,4H24P@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 - 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004158_00690 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKAEGITGEVLLQNLEC(Carbamidomethyl)R MGYG000003697_01442 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0522@1|root,COG0522@2|Bacteria,4NEMZ@976|Bacteroidetes,2FMRC@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01442 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 0 0 457798 0 0 277762 0 0 0 0 347800 0 0 0 0 0 0 0 0 0 0 396936 0 193915 0 0 0 0 0 0 0 197163 163454 0 0 0 0 141599 0 0 275781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 484628 0 0 472396 0 0 0 0 533514 0 0 0 0 0 0 326000 0 0 0 371872 1061653 269605 0 0 0 269604 0 0 0 399968 0 0 0 0 0 394591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKAETEAAATEEAPAAEATEAPAEA MGYG000000243_01032 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0228@1|root,COG0228@2|Bacteria,4NNY8@976|Bacteroidetes,2FN6N@200643|Bacteroidia,4ANWZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01032 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 0 2778322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1992511 0 0 0 0 2103779 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKDFATVITVDDQGNIK MGYG000002143_00771 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp900545585|m__MGYG000002143 1.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,267P3@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 S 1.0 ABC transporter substrate-binding protein PnrA-like 1.0 tmpC 1.0 - 1.0 - 1.0 ko:K07335 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Bmp,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002143_00771 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07335:bmpA, bmpB, tmpC; basic membrane protein A and related proteins 1.0 none 1.0 0 0 109131 0 0 118271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663447 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 468816 0 382012 0 0 0 0 0 0 0 0 212284 0 0 0 0 0 0 0 590265 0 0 568103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428746 0 497628 0 0 0 0 0 0 0 0 449357 0 0 0 0 446537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320253 0 99307 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKDNVVTTPGYDSSAYPR MGYG000003681_03037 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides stercoris|m__MGYG000003681 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FWS8@200643|Bacteroidia,4APMN@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_03037 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKEELKPEVYIQYQGR MGYG000002517_02585 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 2E7V3@1|root,3329Y@2|Bacteria,1VHFN@1239|Firmicutes,24SN8@186801|Clostridia 1.0 186801|Clostridia 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02585 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 210348 452592 0 295240 0 251717 0 166844 0 214777 0 0 235115 0 266251 0 311556 0 0 211917 0 0 158552 0 262109 0 0 0 0 0 0 0 0 280601 238636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 172010 0 0 229637 0 0 0 122335 0 190556 0 0 0 0 240402 0 192463 0 195547 0 0 0 0 0 0 474186 0 0 0 0 0 0 0 0 0 99083 322809 0 1222157 96815 0 938036 0 522338 0 873548 728362 219652 217250 259991 0 1000079 770713 0 370478 0 448214 0 946000 0 0 0 835344 659302 905039 0 0 0 0 0 0 452622 0 993764 744036 0 674143 899336 1079469 0 0 670367 0 535523 584465 1411770 999228 660874 0 933968 1320076 0 999518 0 881853 0 932160 726587 0 1248104 854246 434889 810160 0 0 0 0 0 1379099 819566 0 769541 768733 991239 +AAKEQNIATAILVGDEAK MGYG000001315_01872 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0280@1|root,COG0280@2|Bacteria,1TRQU@1239|Firmicutes,24857@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM Phosphate acetyl butaryl transferase 1.0 ptb 1.0 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747,GO:0050182 1.0 2.3.1.19 1.0 ko:K00634 1.0 ko00650,ko01100,map00650,map01100 1.0 - 1.0 R01174 1.0 RC00004,RC02816 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01872 1.0 phosphate butyryltransferase. phosphotransbutyrylase. - butanoyl-CoA + phosphate = butanoyl phosphate + CoA. 1.0 1.0 1.0 1.0 Butanoate metabolism|Metabolic pathways 1.0 K00634:ptb; phosphate butyryltransferase [EC:2.3.1.19] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKERC(Carbamidomethyl)DAGFGVNNTGLAVFLDFSEAINR MGYG000000196_02827 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_02827 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKGEKDYYR MGYG000000223_00603 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0747@1|root,COG0747@2|Bacteria 1.0 2|Bacteria 1.0 E 1.0 dipeptide transport 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_00603 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 521541 0 0 0 0 0 0 0 0 816911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKGGTLDEVIEAAQK MGYG000004735_02294 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,21YFJ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 2.7.1.121 1.0 ko:K05878 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Dak1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_02294 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways 1.0 K05878:dhaK; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaK [EC:2.7.1.121] 1.0 none 1.0 0 0 0 1562652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 862618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKLNVVYEK MGYG000000245_00061;MGYG000000404_00348 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0151@1|root,arCOG04415@2157|Archaea,2XTRV@28890|Euryarchaeota,23NMV@183925|Methanobacteria 1.0 183925|Methanobacteria 1.0 F 1.0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 1.0 purD 1.0 - 1.0 6.3.4.13 1.0 ko:K01945 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04144 1.0 RC00090,RC00166 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GARS_A,GARS_C,GARS_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000245_00061 0.5 phosphoribosylamine--glycine ligase. phosphoribosylglycinamide synthetase. Formerly EC 6.3.1.3. 5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)- (5-phospho-beta-D-ribosyl)glycinamide + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01945:purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKM(Oxidation)DSSSEITK MGYG000000074_00133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00133 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 155112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207855 0 212998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359257 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247569 0 290982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAKTADEKPEK MGYG000001300_02380 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position 1.0 glgB 1.0 - 1.0 2.4.1.18 1.0 ko:K00700 1.0 ko00500,ko01100,ko01110,map00500,map01100,map01110 1.0 M00565 1.0 R02110 1.0 - 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 CBM48,GH13 1.0 - 1.0 Alpha-amylase,Alpha-amylase_C,CBM_48 1.0 2.4.1.18 1.0 CBM48 1.0 GH13+CBM48 1.0 CBM48+GH13_9 1.0 MGYG000001300_02380 1.0 1,4-alpha-glucan branching enzyme. glycogen branching enzyme. Converts amylose into amylopectin.-!-The description (official name) requires a qualification depending on the product, glycogen or amylopectin, e.g. glycogen branching enzyme, amylopectin branching enzyme.-!-The latter has frequently been termed Q-enzyme. Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00700:GBE1, glgB; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328419 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134738 0 +AAL(Xle->Gln)MDEWFSGK MGYG000002080_01068 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900544825|m__MGYG000002080 1.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the transketolase family 1.0 tkt 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002080_01068 1.0 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 938315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAL(Xle->Val)VHGLK MGYG000002528_01864;MGYG000002756_00379;MGYG000002596_01649;MGYG000003215_00849;MGYG000004055_01475;MGYG000003500_00156;MGYG000004735_02050;MGYG000001141_01291;MGYG000002212_00566;MGYG000000164_02739;MGYG000003786_01019;MGYG000000204_02185;MGYG000001374_01171;MGYG000001689_04166;MGYG000002141_01720;MGYG000003486_01280;MGYG000001793_01089;MGYG000000078_01647;MGYG000004558_00350;MGYG000000278_00938;MGYG000002835_01005;MGYG000003442_01319;MGYG000004359_01015;MGYG000000139_02422;MGYG000001619_00808;MGYG000001493_03358;MGYG000000080_02280;MGYG000000028_01597;MGYG000004879_02709 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,25QPE@186804|Peptostreptococcaceae 0.27586206896551724 186801|Clostridia 1.0 J 0.7241379310344828 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.41379310344827586 rpsK 0.41379310344827586 - 1.0 - 1.0 ko:K02948 0.41379310344827586 ko03010,map03010 0.7241379310344828 M00178,M00179 0.7241379310344828 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.7241379310344828 - 1.0 - 1.0 - 0.7241379310344828 Ribosomal_S11 0.41379310344827586 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01864 0.034482758620689655 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.7241379310344828 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 0.41379310344827586 none 1.0 0 0 0 0 738387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAAAEGDYK MGYG000000437_00955;MGYG000000074_00133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000437_00955 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3590720 0 0 0 2908334 0 0 0 2339026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2266625 0 2516072 0 0 0 2155420 0 0 0 2677945 0 0 0 0 416584 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 473309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAAAGVPVVYTGPVDR MGYG000003683_01311 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0562@1|root,COG0562@2|Bacteria,2GK2Z@201174|Actinobacteria,4CZ2W@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 M 1.0 UDP-galactopyranose mutase 1.0 glf 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008767,GO:0009273,GO:0009987,GO:0016020,GO:0016853,GO:0016866,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071766,GO:0071840,GO:0071944 1.0 5.4.99.9 1.0 ko:K01854 1.0 ko00052,ko00520,map00052,map00520 1.0 - 1.0 R00505,R09009 1.0 RC00317,RC02396 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iNJ661.Rv3809c 1.0 GLF,NAD_binding_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01311 1.0 UDP-galactopyranose mutase. - - UDP-alpha-D-galactose = UDP-alpha-D-galactofuranose. 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism 1.0 K01854:glf; UDP-galactopyranose mutase [EC:5.4.99.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 332280 0 0 0 0 0 0 0 0 0 0 0 707021 0 0 0 0 0 624175 0 0 0 512684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAAEIPADLK MGYG000004769_01202 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,4H2K7@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000004769_01202 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 152202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 600323 0 0 0 0 590236 0 0 749067 0 0 0 0 494931 399581 0 0 0 0 0 0 0 0 0 464821 0 0 0 554949 708561 519163 0 0 382912 0 497807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAAGGEAAK MGYG000002494_01061 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 28I6Q@1|root,2Z89M@2|Bacteria,1MWCS@1224|Proteobacteria,1RN42@1236|Gammaproteobacteria,3WV68@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Protein of unknown function (DUF1471) 1.0 ydgH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1471 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01061 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 966213 727069 0 872631 2516150 0 0 0 917074 0 0 0 0 914464 0 0 0 0 0 1104134 710263 0 765775 0 0 0 0 1083592 1071654 0 0 771468 0 0 0 0 0 0 2224555 3522890 0 2577164 4997838 0 0 0 2851773 0 0 0 0 1513789 0 0 0 0 0 3243536 5122623 0 3665789 0 0 0 0 3910255 2601995 0 0 4032073 0 0 0 0 1551970 0 211851 0 0 0 622947 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 737768 0 0 0 0 0 0 0 265957 0 0 0 0 0 0 0 0 0 0 735417 0 0 848185 0 0 0 804251 0 0 0 0 765385 0 0 0 0 0 0 1123637 0 1153927 0 0 0 0 0 325113 0 0 622477 0 0 0 0 707039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALADYK MGYG000004628_01120 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__|m__MGYG000004628 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 - 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000004628_01120 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 908696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAEAQEVK MGYG000003697_01183;MGYG000002293_01687 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0078@1|root,COG0078@2|Bacteria,4NEYX@976|Bacteroidetes,2FNR9@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the ATCase OTCase family 1.0 argF 1.0 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.1.3.11,2.1.3.9 1.0 ko:K09065,ko:K13043 1.0 ko00220,ko01100,ko01230,map00220,map01100,map01230 1.0 M00845 1.0 R07245,R08937 1.0 RC00096 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 OTCace,OTCace_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01183 0.5 N-succinylornithine carbamoyltransferase. | N-acetylornithine carbamoyltransferase. succinylornithine transcarbamylase. | N-acetylornithine transcarbamylase. Specific for N-succinyl-L-ornithine and cannot use either L-ornithine (see EC 2.1.3.3) or N-acetyl-L-ornithine (see EC 2.1.3.9) as substrate.-!-However, a single amino-acid substitution (Pro90Glu) is sufficient to switch the enzyme to one that uses N-acetyl-L-ornithine as substrate.-!-It is essential for de novo arginine biosynthesis in the obligate anaerobe Bacteroides fragilis, suggesting that this organism uses an alternative pathway for synthesizing arginine. | Differs from EC 2.1.3.3.-!-This enzyme replaces EC 2.1.3.3 in the canonic arginine biosynthetic pathway of several eubacteria and has no catalytic activity with L-ornithine as substrate. carbamoyl phosphate + N(2)-succinyl-L-ornithine = H(+) + N(2)-succinyl-L- citrulline + phosphate. | carbamoyl phosphate + N(2)-acetyl-L-ornithine = H(+) + N(2)-acetyl-L- citrulline + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of amino acids 1.0 K09065:argF; N-acetylornithine carbamoyltransferase [EC:2.1.3.9]|K13043:argF; N-succinyl-L-ornithine transcarbamylase [EC:2.1.3.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278862 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2619541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAELSK MGYG000000074_01070 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0457@1|root,COG0457@2|Bacteria,4PESY@976|Bacteroidetes,2G21B@200643|Bacteroidia,22UIH@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01070 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 625174 0 0 761938 0 0 0 0 0 0 0 645638 0 0 445492 0 225685 0 0 529240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 800430 0 0 830728 0 0 0 0 778293 0 0 356543 0 0 728734 0 392744 0 0 911488 0 0 0 0 0 642455 0 0 0 456306 560080 0 0 0 0 0 661276 0 279198 0 0 0 0 0 0 0 498698 0 0 0 0 0 0 0 0 0 0 597546 0 0 0 0 0 0 0 0 0 0 309755 0 0 0 0 0 0 0 414774 0 0 219691 0 0 0 0 414084 0 0 163392 0 0 0 0 0 0 0 716422 0 0 0 0 0 528639 0 0 0 334283 184515 0 0 0 0 0 393575 0 2549367 0 0 2930800 0 0 0 0 2797146 0 0 2661911 0 0 2129224 0 2676854 0 0 4261168 0 0 0 0 0 3597373 0 0 0 4693019 1704910 0 0 0 0 0 2710037 0 +AALAGAK MGYG000000045_02628 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG0126@1|root,COG0126@2|Bacteria,2NNN1@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 G 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iSB619.SA_RS04145 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000045_02628 1.0 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 152618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 570038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1190036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAGFADVK MGYG000001319_02401 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,4BW9Z@830|Butyrivibrio 1.0 186801|Clostridia 1.0 E 1.0 Threonine synthase N terminus 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001319_02401 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1136860 0 0 0 0 1396587 0 0 0 0 1224072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141613 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 551210 0 0 0 0 596286 0 0 0 0 491258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 337290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132808 0 0 0 0 664278 0 0 0 0 687642 0 0 0 0 0 0 0 0 0 0 +AALAGFADVPGTK MGYG000002528_02105;MGYG000000080_00353;MGYG000000262_02109;MGYG000001379_01833 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,2685I@186813|unclassified Clostridiales 0.5 186801|Clostridia 1.0 E 1.0 Threonine synthase N terminus 0.75 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02105 0.25 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 0 611855 0 0 0 659171 0 0 0 0 0 0 0 0 0 0 364676 0 0 0 0 968449 0 209840 0 0 0 0 1005979 0 0 0 0 0 0 0 0 0 0 839551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 820805 0 0 0 0 0 0 0 0 0 0 2889101 0 0 0 1324525 0 0 0 0 0 0 0 0 0 0 1712878 0 0 0 0 3218645 0 956676 0 0 0 0 1670518 0 0 0 0 0 0 0 0 0 0 780969 0 0 0 442186 0 0 0 0 0 0 0 0 0 0 611389 0 0 0 0 511871 0 656530 0 0 0 0 2202195 0 0 0 0 0 0 0 0 0 0 268414 0 0 0 811057 0 0 0 0 0 0 0 0 0 0 462901 0 0 0 0 522717 0 478770 0 0 0 0 1099013 0 0 0 0 0 0 0 0 0 +AALAGFADVPGTR MGYG000004733_03061;MGYG000000171_00617 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3XZ3J@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 8.87 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004733_03061 0.5 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 0 0 0 0 0 1144848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 812562 0 770145 0 0 0 0 763835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 586063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 846621 0 932795 0 0 0 0 1132151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 315061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAGFSDVPGTK MGYG000002517_01577 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Threonine synthase 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01577 1.0 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 1199378 684368 811378 1316763 834923 1063716 966579 1393852 1106940 1696436 643452 759416 372671 1061939 1330419 818646 1142672 0 1344476 1205850 1326695 1113648 0 536306 1286085 1224198 994164 0 302268 980478 353529 738336 533715 1292755 1231209 965395 987651 479097 6516858 15406084 0 1371426 0 803407 1245571 1337915 0 3292310 2186087 2078427 5235945 1032010 650088 3248036 4656987 0 2766838 4936028 3825355 1601373 0 6259809 5191176 1426762 2850245 0 9894837 1775936 0 7547867 4435195 8148302 310353 2648266 0 0 589142 577467 397339 521162 151691 140133 477211 307558 432285 650544 679203 0 202257 131083 601552 336834 686056 0 493122 678258 545705 15125633 0 542453 848859 796253 390476 0 257234 510245 421489 12455539 0 417413 1096454 341103 548949 10287638 6084004 0 2524027 4347723 0 2647038 3064964 5668920 5047465 3126431 3271261 2638826 2392281 5443142 5311927 3007995 3901512 0 3601607 4785805 3307019 2026369 0 2105333 4387189 4178705 4796413 0 2074259 3751569 4542227 565721 2694319 3022780 4572985 3929670 6784327 3115630 2741262 1849087 3029354 150737 2306816 3605901 2857191 2751679 3361236 3808682 2139091 2942269 1523763 3097950 4346014 0 3983939 0 2723897 3040844 3443511 2614091 0 4865134 3979178 3101744 2710655 0 580339 2574616 2404981 1194022 2717612 3018412 2537706 3708362 3776716 3015517 +AALAGGLK MGYG000003937_01848 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01848 1.0 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAGGLKPIIC(Carbamidomethyl)VGESLDQR MGYG000003921_00579;MGYG000001157_01821 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) 1.0 tpiA 1.0 - 1.0 5.3.1.1 1.0 ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003 1.0 R01015 1.0 RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 iHN637.CLJU_RS19265 1.0 TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_00579 0.5 triose-phosphate isomerase. triose phosphoisomerase. - D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 354155 0 0 0 0 0 296409 0 0 0 0 241264 0 0 0 0 298384 0 269144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1603098 0 0 0 0 0 923462 0 0 0 0 926856 0 0 0 0 685355 0 915271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532026 0 0 0 0 0 199177 0 0 0 0 288340 0 0 0 0 266414 0 257023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633661 0 0 0 0 0 270455 0 0 0 0 0 0 0 0 0 0 0 418406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1171013 0 0 0 0 0 1024514 0 0 0 0 1155128 0 0 0 0 1234348 0 760359 0 0 0 0 0 0 0 0 +AALANAALNAER MGYG000000591_01538;MGYG000001365_01289 genus d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A 1.0 COG0845@1|root,COG0845@2|Bacteria,1TQV0@1239|Firmicutes,4H1W4@909932|Negativicutes 1.0 909932|Negativicutes 1.0 M 1.0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000591_01538 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1049371 0 0 0 0 0 0 1009898 0 0 909186 0 975828 0 0 0 1041989 673340 936187 0 0 0 765838 0 0 1430483 0 0 0 0 0 0 0 +AALANAR MGYG000003683_00464;MGYG000000003_01871 domain d__Bacteria 1.0 COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4CZ3J@85004|Bifidobacteriales 0.5 201174|Actinobacteria 0.5 H 0.5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 0.5 tal 0.5 - 1.0 2.2.1.2 0.5 ko:K00616 0.5 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 0.5 M00004,M00007 0.5 R01827 0.5 RC00439,RC00604 0.5 ko00000,ko00001,ko00002,ko01000 0.5 - 1.0 - 1.0 - 1.0 TAL_FSA 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00464 0.5 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 0.5 0.5 0.5 0.5 Pentose phosphate pathway|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.5 K00616:TALDO1, talB, talA; transaldolase [EC:2.2.1.2] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALANDSFLSAASFQETTR MGYG000001300_00284;MGYG000001255_01103 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3WGVS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000001300_00284 0.5 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 211088 0 468816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306631 0 0 0 0 0 0 0 335158 0 0 0 0 330659 893642 610374 441176 1065938 527112 642789 938703 453418 739541 0 498703 649069 0 861978 0 0 1056926 0 1007016 969493 0 741050 0 683336 986641 998006 743943 0 0 462962 714220 0 770631 669276 0 705071 689866 469478 0 381504 0 0 0 333823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 313480 0 0 0 0 254183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364625 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALANIFSELPNSEK MGYG000002494_04301 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0354@1|root,COG0354@2|Bacteria,1N852@1224|Proteobacteria,1RPWB@1236|Gammaproteobacteria,3WWIY@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication 1.0 ygfZ 1.0 GO:0003674,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0019842,GO:0022607,GO:0031163,GO:0031406,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071840,GO:0072341,GO:0097159,GO:1901363 1.0 - 1.0 ko:K06980 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03016 1.0 - 1.0 - 1.0 - 1.0 GCV_T,GCV_T_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04301 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06980:ygfZ; tRNA-modifying protein YgfZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 233145 0 0 0 0 0 0 0 727628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 801803 0 0 0 0 538428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALANMVQAAQNLR MGYG000002506_03505 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,1RMBA@1236|Gammaproteobacteria,3XP3E@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation 1.0 metE 1.0 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0032259,GO:0034641,GO:0035999,GO:0036211,GO:0042084,GO:0042085,GO:0042558,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0050667,GO:0051186,GO:0071704,GO:0140096,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.1.1.14 1.0 ko:K00549 1.0 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 1.0 M00017 1.0 R04405,R09365 1.0 RC00035,RC00113,RC01241 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iE2348C_1286.E2348C_4130,iECO103_1326.ECO103_4334,iECO111_1330.ECO111_4657,iECO26_1355.ECO26_4756,iECW_1372.ECW_m4131,iEKO11_1354.EKO11_4528,iPC815.YPO3788,iWFL_1372.ECW_m4131 1.0 Meth_synt_1,Meth_synt_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_03505 1.0 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase. tetrahydropteroylglutamate-homocysteine transmethylase. Requires phosphate.-!-The enzyme from Escherichia coli also requires a reducing system.-!-Unlike EC 2.1.1.13 this enzyme does not contain cobalamin. 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Selenocompound metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K00549:metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1493668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1594868 0 1727056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAPDAFQR MGYG000001306_03308;MGYG000001783_02428 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_03308 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3522657 0 0 0 0 3303324 0 0 0 0 3740081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 668831 0 0 0 0 1022394 0 0 0 0 1119958 0 0 0 0 0 0 0 0 0 0 +AALAQFVGK(Lys->Arg) MGYG000000262_01263 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,25UYQ@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsI 1.0 - 1.0 2.7.3.9,2.7.9.2 1.0 ko:K01007,ko:K08483 1.0 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060 1.0 M00173,M00374 1.0 R00199 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_01263 1.0 phosphoenolpyruvate--protein phosphotransferase. | pyruvate, water dikinase. sugar--PEP phosphotransferase enzyme I. | pyruvate,water dikinase. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. | ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Phosphotransferase system (PTS) 1.0 K01007:pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2]|K08483:ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3007794 0 0 0 2084736 0 0 0 0 0 0 0 0 0 0 2727032 0 1961270 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 591322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAQILVK MGYG000002438_01767 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG3063@1|root,COG3063@2|Bacteria,4PKG6@976|Bacteroidetes,2G3G2@200643|Bacteroidia,2322F@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 NU 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01767 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2260438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAQVEK MGYG000002992_02024;MGYG000000198_04879;MGYG000001496_02754;MGYG000002279_02611;MGYG000001789_02120 domain d__Bacteria 1.0 COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,27VNQ@189330|Dorea 0.4 186801|Clostridia 0.8 U 0.8 Preprotein translocase subunit 0.8 yajC 0.8 - 1.0 - 0.8 ko:K03210 0.8 ko02024,ko03060,ko03070,map02024,map03060,map03070 0.8 M00335 0.8 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 0.8 3.A.5.1,3.A.5.2 0.8 - 1.0 - 1.0 Ftsk_gamma,YajC 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002992_02024 0.2 - - - - 0.8 0.8 0.8 0.8 Quorum sensing|Protein export|Bacterial secretion system 0.8 K03210:yajC; preprotein translocase subunit YajC 0.8 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALATESFLSAASFQETTR MGYG000003474_00162 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__QALW01|g__UMGS1322|s__|m__MGYG000003474 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,36EQT@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000003474_00162 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALAVC(Carbamidomethyl)K MGYG000001338_02425;MGYG000002966_01691;MGYG000000184_00685 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02425 0.3333333333333333 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00197:cdhE, acsC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] 1.0 none 1.0 0 693086 2289228 0 3707915 0 0 1932430 0 0 2548945 0 0 0 0 2791339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1178721 2915237 1577755 0 0 0 0 2205377 0 8305391 2406650 0 3289220 0 0 2026142 0 0 2524176 0 0 0 0 1953403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6082149 3935857 2061902 0 0 0 0 1119463 0 4873660 1850658 0 575920 0 0 2534302 0 0 1944151 0 0 0 0 2573464 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1568260 4257263 3363287 0 0 0 0 2182801 0 4378384 3728427 0 6664444 0 0 2174252 0 0 2816815 0 0 0 0 2403452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6972213 5241133 4611477 0 0 0 0 5039745 0 7373424 5731163 0 2773006 0 0 2539007 0 0 4596771 0 0 0 0 3585023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7419413 6937284 6497517 0 0 0 0 5078291 +AALAVQAK MGYG000000077_02459;MGYG000004784_01123;MGYG000000262_01988 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25VEG@186806|Eubacteriaceae 0.6666666666666666 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.6666666666666666 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000077_02459 0.3333333333333333 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 1823239 1987652 2744749 1264181 3615779 2130197 1163671 1857930 1314245 1651384 2438726 2075405 3685991 2363490 2311564 3225047 1398742 0 2579205 2013254 1924443 3086709 0 1406880 2550908 2053279 1603904 0 0 0 0 2043031 2101320 2524283 2194136 0 1670442 2290199 2380820 2275224 837873 1654456 805027 884814 3016759 1691944 1780092 870598 837336 914431 988366 1005022 1683263 596383 987442 0 1820458 2110251 1330633 705751 0 1727084 1152104 1650112 1411576 0 0 0 0 953119 632857 1965666 2126433 0 0 983669 6252158 8884319 4355070 10576297 3586652 6270858 3714956 6989230 5406180 6811631 5017193 3590022 6909236 6861524 7814270 6198278 6017580 0 7208367 8099334 6077458 9080951 0 4638360 7686999 6613995 7711536 0 0 0 0 6503681 4163149 7592053 6968662 0 5848596 2620804 3040331 2750846 3552932 4010858 3487868 2328235 2584749 3024390 1817200 4076738 0 3168985 3733782 2198610 2962329 5389259 4026363 0 2565841 2547798 2415025 3216889 0 3381749 1913365 1638279 2418905 0 0 0 0 2815602 3909645 1820075 2997170 0 2724224 3006363 623779 1790799 2471373 1270200 793888 1634172 620692 1270492 908840 828183 2978853 1110012 1399163 1114657 707556 2092317 860690 0 740958 431428 580434 2063902 0 2268771 1185741 687356 622007 0 0 0 0 1928511 3306849 716250 884492 0 628814 2049853 +AALC(Carbamidomethyl)SDC(Carbamidomethyl)FSAEATR MGYG000002298_00410 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp000436615|m__MGYG000002298 1.0 COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3XZXS@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 rpiB 1.0 - 1.0 5.3.1.6 1.0 ko:K01808 1.0 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01056,R09030 1.0 RC00376,RC00434 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 LacAB_rpiB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_00410 1.0 ribose-5-phosphate isomerase. ribose phosphate isomerase. Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate. aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Fructose and mannose metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01808:rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] 1.0 none 1.0 0 0 0 0 0 575455 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 531057 0 395649 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322713 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALC(Carbamidomethyl)SDTFSAHATR MGYG000002528_01063 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0394@1|root,COG0698@1|root,COG0394@2|Bacteria,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,268XB@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 G 1.0 Ribose/Galactose Isomerase 1.0 rpiB 1.0 - 1.0 5.3.1.6 1.0 ko:K01808 1.0 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01056,R09030 1.0 RC00376,RC00434 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 LMWPc,LacAB_rpiB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01063 1.0 ribose-5-phosphate isomerase. ribose phosphate isomerase. Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate. aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Fructose and mannose metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01808:rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] 1.0 none 1.0 0 128385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1032607 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143570 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALC(Carbamidomethyl)TDC(Carbamidomethyl)FC(Carbamidomethyl)AEATR MGYG000004735_01991 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3XZXS@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 rpiB 1.0 - 1.0 5.3.1.6 1.0 ko:K01808 1.0 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01056,R09030 1.0 RC00376,RC00434 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 LacAB_rpiB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_01991 1.0 ribose-5-phosphate isomerase. ribose phosphate isomerase. Also acts on D-ribose 5-diphosphate and D-ribose 5-triphosphate. aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Fructose and mannose metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01808:rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDAC(Carbamidomethyl)SSSFDIR MGYG000000133_02045 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3XZ9K@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location CytoplasmicMembrane, score 1.0 ntpI 1.0 - 1.0 - 1.0 ko:K02123 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 V_ATPase_I 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02045 1.0 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways 1.0 K02123:ATPVI, ntpI, atpI; V/A-type H+/Na+-transporting ATPase subunit I 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 428664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1215047 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDAGSAAAQR MGYG000002477_02054;MGYG000002494_03995 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1RCBV@1224|Proteobacteria,1S2HK@1236|Gammaproteobacteria,3WVJ5@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 CQ 1.0 Ethanolamine utilization protein EutK C-terminus 1.0 eutK 1.0 GO:0003674,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0031469,GO:0031471,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0050896 1.0 - 1.0 ko:K04025 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC,EutK_C,HTH_IclR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002477_02054 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04025:eutK; ethanolamine utilization protein EutK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 984652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 932078 0 0 0 0 723482 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDAIYHAGK MGYG000000179_03466 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG1527@1|root,COG1527@2|Bacteria,1U6WZ@1239|Firmicutes,249XD@186801|Clostridia,267RG@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 ATP synthase (C/AC39) subunit 1.0 ntpC 1.0 - 1.0 - 1.0 ko:K02119 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 DUF2764,vATP-synt_AC39 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03466 1.0 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways 1.0 K02119:ATPVC, ntpC, atpC; V/A-type H+/Na+-transporting ATPase subunit C 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 735400 518323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDALER MGYG000002478_02977;MGYG000004797_03856;MGYG000000243_01217 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1995@1|root,COG1995@2|Bacteria,4NEUR@976|Bacteroidetes,2FN0X@200643|Bacteroidia,4AN0A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the PdxA family 1.0 pdxA 1.0 - 1.0 1.1.1.262 1.0 ko:K00097 1.0 ko00750,ko01100,map00750,map01100 1.0 M00124 1.0 R05681,R05837,R07406 1.0 RC00089,RC00675,RC01475 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PdxA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_02977 0.3333333333333333 4-hydroxythreonine-4-phosphate dehydrogenase. NAD(+)-dependent threonine 4-phosphate dehydrogenase. The enzyme is part of the biosynthesis pathway of the cofactor pyridoxal 5'-phosphate found in anaerobic bacteria. 4-(phosphooxy)-L-threonine + NAD(+) = 3-amino-2-oxopropyl phosphate + CO2 + NADH. 1.0 1.0 1.0 1.0 Vitamin B6 metabolism|Metabolic pathways 1.0 K00097:pdxA; 4-hydroxythreonine-4-phosphate dehydrogenase [EC:1.1.1.262] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1239770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 658355 0 0 1451316 0 0 0 0 851653 0 1646593 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432470 0 0 0 0 0 0 0 0 0 456569 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 691522 0 0 0 0 618042 0 0 0 0 0 0 0 468388 0 0 0 0 184019 0 293680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDATTNALK MGYG000003697_01550;MGYG000002834_01007 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01550 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3704416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1687414 0 0 0 0 2359449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDAYYEQYGAK MGYG000002528_00495;MGYG000000184_02212;MGYG000001338_00074 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,3WGS1@541000|Ruminococcaceae 0.3333333333333333 186801|Clostridia 1.0 F 1.0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) 1.0 pyrE 1.0 - 1.0 2.4.2.10 1.0 ko:K00762 1.0 ko00240,ko01100,map00240,map01100 1.0 M00051 1.0 R01870 1.0 RC00611 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyltran 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00495 0.3333333333333333 orotate phosphoribosyltransferase. orotidylic acid phosphorylase. The enzyme from higher eukaryotes also catalyzes the reaction listed as EC 4.1.1.23. diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00762:pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1799899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2047922 0 0 0 0 0 0 +AALDEVGEEQHR MGYG000002794_00763;MGYG000002926_00664;MGYG000002882_00085;MGYG000002720_00861;MGYG000002143_01959;MGYG000001733_00672;MGYG000004196_01673;MGYG000004475_00752;MGYG000004487_00297;MGYG000002086_01355 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0274@1|root,COG0274@2|Bacteria,1TPA0@1239|Firmicutes,249YN@186801|Clostridia,36F7D@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 F 1.0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit 1.0 kamD 1.0 - 1.0 5.4.3.3 1.0 ko:K01844 1.0 ko00310,map00310 1.0 - 1.0 R02852,R03275 1.0 RC00719 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Lys-AminoMut_A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_00763 0.1 lysine 5,6-aminomutase. D-lysine 5,6-aminomutase. This enzyme is a member of the 'AdoMet radical' (radical SAM) family.-!-A 5'-deoxyadenosyl radical is generated during the reaction cycle by reductive cleavage of adenosylcobalamin, which is regenerated at the end of the reaction.-!-Formerly EC 5.4.3.4. (1) (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate. (2) D-lysine = (2R,5S)-2,5-diaminohexanoate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K01844:kamD; beta-lysine 5,6-aminomutase alpha subunit [EC:5.4.3.3] 1.0 none 1.0 2635207 1918916 1539996 2020297 1234816 2197549 2755175 2387776 2584108 2167687 1403252 1441908 1363531 2274396 1951392 1388084 1409946 1286781 1678253 1928238 2127638 2040667 1149928 2068017 2194530 3031222 1911328 1494318 2333425 1330192 1880363 1327018 1626870 2432534 2080261 2444948 2596190 1549066 492309 56280 0 466204 270691 169099 457162 551596 406348 390685 52751 242298 84461 364190 374037 98739 191495 0 535727 549501 231101 0 81366 202834 290214 460095 514703 105495 349157 247938 177883 131857 117075 420666 391844 470521 556882 313467 1736263 1389776 1123844 1712733 580940 706753 1702447 2068051 1453116 1657876 841108 1213739 1062062 1793136 1749358 1071140 1562359 271991 1686861 1641400 1811705 1350557 342149 860902 1586523 1893767 1818700 449063 1553363 1707751 614658 915062 1284481 1853829 1160265 1505628 1027434 1214950 921357 978351 852514 1007763 805957 1083159 1189972 1135266 1268196 1271015 616390 647560 634174 1200040 990825 816685 1558529 203463 1200624 996684 771234 810696 242581 866503 1069634 1003615 1101393 318513 1384567 772741 765559 943652 1032399 1399466 857751 1034447 1120070 811800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94465 260077 600759 0 0 0 736259 0 0 0 0 0 333929 0 0 0 0 +AALDGAYEQWR MGYG000002478_01888 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 2DBE2@1|root,2Z8QB@2|Bacteria,4NK8H@976|Bacteroidetes,2FMIR@200643|Bacteroidia,4AP06@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01888 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 798801 0 0 0 0 1299559 0 0 0 0 1224140 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1026019 0 0 0 0 1143901 0 0 0 0 1142646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 669661 0 0 0 0 467215 0 0 0 0 560839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246266 0 0 0 0 412025 0 0 0 0 161809 0 0 0 0 0 0 0 0 0 0 +AALDHQQER MGYG000003683_00678 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CYWE@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 F 1.0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates 1.0 pyrG 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.0 6.3.4.2 1.0 ko:K01937 1.0 ko00240,ko01100,map00240,map01100 1.0 M00052 1.0 R00571,R00573 1.0 RC00010,RC00074 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iNJ661.Rv1699 1.0 CTP_synth_N,GATase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00678 1.0 CTP synthase (glutamine hydrolyzing). UTP--ammonia ligase. The enzyme contains three functionally distinct sites: an allosteric GTP-binding site, a glutaminase site where glutamine hydrolysis occurs (cf. EC 3.5.1.2), and the active site where CTP synthesis takes place.-!-The reaction proceeds via phosphorylation of UTP by ATP to give an activated intermediate 4-phosphoryl UTP and ADP.-!-Ammonia then reacts with this intermediate generating CTP and a phosphate.-!-The enzyme can also use ammonia from the surrounding solution. ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K01937:pyrG, CTPS; CTP synthase [EC:6.3.4.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 109920 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1278017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143567 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 266076 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDIATDPWGIK MGYG000000251_01623;MGYG000000217_00189 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3WH9Z@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 O 1.0 SPFH Band 7 PHB domain protein 0.5 qmcA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Band_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000251_01623 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 698654 0 0 0 0 960837 0 0 0 0 1034191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402491 0 0 0 0 572023 0 0 0 0 523925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDKYGSGC(Carbamidomethyl)AGSR MGYG000002293_02198;MGYG000002960_00103;MGYG000002603_02013;MGYG000002834_01646;MGYG000003697_02473 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0156@1|root,COG0156@2|Bacteria,4NFBU@976|Bacteroidetes,2FM0N@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 8-amino-7-oxononanoate synthase 1.0 bioF 1.0 - 1.0 2.3.1.29,2.3.1.47 1.0 ko:K00639,ko:K00652 1.0 ko00260,ko00780,ko01100,map00260,map00780,map01100 1.0 M00123,M00573,M00577 1.0 R00371,R03210,R10124 1.0 RC00004,RC00039,RC00394,RC02725 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_02198 0.2 glycine C-acetyltransferase. | 8-amino-7-oxononanoate synthase. 2-amino-3-ketobutyrate coenzyme A ligase. | AONS. Acts in concert with EC 1.1.1.103 in the degradation of threonine to form glycine.-!-This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex. | The enzyme catalyzes the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis.-!-Pimeloyl-CoA can be used with lower efficiency. acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA. | 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Biotin metabolism|Metabolic pathways 1.0 K00639:kbl, GCAT; glycine C-acetyltransferase [EC:2.3.1.29]|K00652:bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 264385 0 0 0 0 0 0 256826 0 0 0 0 0 0 0 0 0 102267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1648561 0 0 1560464 0 0 0 0 1368942 0 0 0 0 0 0 1803861 0 0 0 1944203 1890745 1376647 0 0 0 1055183 0 0 0 0 1368940 0 0 0 0 1296964 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDNFYAR MGYG000002933_01923;MGYG000001783_01377;MGYG000001306_01721;MGYG000002478_00089;MGYG000000243_01768 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,2FM2Z@200643|Bacteroidia,4AN6Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate 1.0 purL 1.0 - 1.0 6.3.5.3 1.0 ko:K01952 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04463 1.0 RC00010,RC01160 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C,GATase_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002933_01923 0.2 phosphoribosylformylglycinamidine synthase. phosphoribosylformylglycinamidine synthetase. - ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D- ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D- ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01952:PFAS, purL; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] 1.0 none 1.0 2060149 0 3461956 1909271 2503296 1852751 1978514 1829622 1862875 0 1437606 2008013 2747920 1819441 1677907 2808353 1913285 1271556 1721364 2011752 1977002 1592425 1673873 2408022 1626820 1824234 0 1640823 0 2199680 3471491 2141641 3494825 0 0 2196527 1740977 3309520 738520 0 963706 989790 1257211 641329 856930 903503 907619 0 589495 732349 2577308 813359 677675 2078344 372183 1520450 774460 892656 982066 880441 2450039 701875 1075688 986139 0 1507546 0 790639 679206 737114 1209275 0 0 778613 842069 1022862 690870 0 772931 625825 938150 810475 702869 309253 714551 0 491388 872511 1461364 456251 370311 1020358 648180 1275613 500758 655701 631871 719351 1393809 724896 509691 598976 0 965860 0 467949 987164 597490 660785 0 0 658928 571451 645380 307979 0 615933 468836 652526 370318 253953 480682 221020 0 351014 381659 393882 154480 463184 449684 485613 270915 435185 381396 154705 544313 628209 393022 450635 423043 0 713870 0 574469 579189 0 564111 0 0 605329 450023 390251 1156602 0 895167 882517 2322498 1327024 1032041 1459055 1296029 0 978776 1147015 2450023 910438 1084103 1803394 1079731 1983620 1143287 1389486 890933 1034435 2210314 1611044 1071389 1071808 0 2432552 0 1204337 1037744 1090673 610259 0 0 951317 1266344 916487 +AALDNITPQVEVK MGYG000000696_01666;MGYG000002218_02523;MGYG000002438_02205;MGYG000000138_02892 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000696_01666 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 478392 0 0 0 0 488995 0 382655 0 0 0 596134 0 0 0 328006 727040 0 0 0 0 0 0 0 0 0 0 559946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1995483 0 0 0 0 0 0 0 0 4082236 0 0 0 0 0 0 0 0 0 0 752203 0 0 0 0 0 0 0 0 0 0 983473 0 0 0 0 584522 0 1352502 0 0 0 936366 0 0 0 708443 1284651 0 0 0 0 0 0 0 0 0 0 803677 0 0 0 0 0 0 0 0 0 0 1239759 0 0 0 0 977325 0 1696127 0 0 0 816294 0 0 0 798446 4717574 0 0 0 0 0 0 0 0 0 0 2024663 0 0 0 0 0 0 0 0 0 0 3784368 0 0 0 0 2689982 0 4337620 0 0 0 2934832 0 0 0 2139617 3849837 0 0 0 0 0 0 0 0 0 0 4612933 0 0 0 0 0 0 +AALDNLEAEMK MGYG000001319_02417 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,4BXZ2@830|Butyrivibrio 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) 1.0 thrS 1.0 - 1.0 6.1.1.3 1.0 ko:K01868 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03663 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 GH28 1.0 MGYG000001319_02417 1.0 threonine--tRNA ligase. threonyl-tRNA synthetase. - ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl- tRNA(Thr). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01868:TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 551138 0 0 0 0 604911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413894 0 0 0 0 0 0 0 0 0 343576 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361601 0 0 0 0 195998 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208922 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDSGEVTLAK MGYG000002978_00874;MGYG000000693_00169 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0085@1|root,COG0085@2|Bacteria,2GJ81@201174|Actinobacteria,4CUH0@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoB 1.0 - 1.0 2.7.7.6 1.0 ko:K03043 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002978_00874 0.5 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03043:rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 996259 0 0 0 0 0 0 0 0 0 0 422698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3714478 0 0 0 0 0 0 0 0 0 0 7633659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4881372 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDSTR MGYG000000243_02894;MGYG000001546_00564;MGYG000000196_02501;MGYG000002478_00488;MGYG000003493_01559;MGYG000003681_01782;MGYG000003697_01494 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0039@1|root,COG0039@2|Bacteria,4NEJ7@976|Bacteroidetes,2FNZ4@200643|Bacteroidia,22VZT@171551|Porphyromonadaceae 0.2857142857142857 976|Bacteroidetes 1.0 C 1.0 Belongs to the LDH MDH superfamily 0.8571428571428571 mdh 1.0 - 1.0 1.1.1.37 1.0 ko:K00024 1.0 ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740 1.0 R00342,R07136 1.0 RC00031 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Ldh_1_C,Ldh_1_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02894 0.14285714285714285 malate dehydrogenase. malic dehydrogenase. Also oxidizes some other 2-hydroxydicarboxylic acids. (S)-malate + NAD(+) = H(+) + NADH + oxaloacetate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Cysteine and methionine metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00024:mdh; malate dehydrogenase [EC:1.1.1.37] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1369094 0 0 0 0 0 0 2717054 0 0 0 0 2491708 0 1595708 0 0 3358610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2429282 0 0 0 0 0 0 2255999 0 0 0 0 4983589 0 1512499 0 0 5021013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1790395 0 0 0 0 0 0 262031 0 0 0 0 2526413 0 1802270 0 0 3796191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1242145 0 0 0 0 0 0 5252541 0 0 0 0 1483925 0 844416 0 0 4610796 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218864 0 0 0 0 0 0 1428941 0 0 0 0 1191520 0 2219427 0 0 632743 0 0 0 0 0 0 0 0 0 0 +AALDVAGAPAQAR MGYG000002926_00666;MGYG000001675_00817 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 kdd 1.0 - 1.0 1.4.1.11 1.0 ko:K18012 1.0 ko00310,map00310 1.0 - 1.0 R03349 1.0 RC00888 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_00666 0.5 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K18012:kdd; L-erythro-3,5-diaminohexanoate dehydrogenase [EC:1.4.1.11] 1.0 none 1.0 0 0 0 152521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 233042 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 730832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469552 0 641944 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 528187 0 858949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDVNIV(Val->Xle)K MGYG000002438_03065 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0561@1|root,COG0561@2|Bacteria,4PKHD@976|Bacteroidetes,2G0K6@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03065 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2113341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALDVNIVK MGYG000002438_03065 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0561@1|root,COG0561@2|Bacteria,4PKHD@976|Bacteroidetes,2G0K6@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03065 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 121778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581628 0 0 0 0 0 0 0 0 392224 0 318472 0 0 0 0 0 0 0 701835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1013940 0 0 0 0 0 0 0 0 303366 0 856414 0 0 0 0 0 0 0 857585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3121013 0 0 0 0 0 0 0 0 3485479 0 1144004 0 0 0 0 0 0 +AALDVNIVKLDDGTPAANYK MGYG000002438_03065 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0561@1|root,COG0561@2|Bacteria,4PKHD@976|Bacteroidetes,2G0K6@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03065 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409824 0 0 0 0 0 0 0 0 387248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 983357 0 0 0 0 0 0 0 0 717248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3345883 0 0 0 0 0 0 0 0 2325090 0 0 0 0 0 0 0 0 +AALDYELLR MGYG000000099_03011 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,248W4@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Family 5 1.0 - 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_03011 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 274460 0 333516 0 0 0 0 0 190296 0 333866 0 0 234642 354753 0 0 0 0 0 0 0 0 0 0 563462 304227 0 345676 0 0 0 287352 192464 0 0 273447 254837 1359454 0 737657 1209475 0 0 1273403 0 1416992 1475469 847780 822992 0 1298683 1263039 0 0 0 0 1321520 0 0 0 0 0 1176506 1478949 0 1343204 1272861 790924 0 872064 1411562 1231540 1258507 1315078 761702 275714 0 269582 310232 0 0 234457 0 298401 516415 511185 537842 0 352038 321587 0 0 0 0 285995 0 0 0 0 0 333355 207888 0 310573 343464 268637 0 98311 735862 580656 331041 300245 637169 142168 0 143501 135084 0 0 174940 0 112463 0 0 93163 0 189522 180528 0 0 0 0 0 0 0 0 0 0 0 326105 0 0 236449 0 0 145981 276219 0 229298 351668 335597 487732 0 865748 778431 0 0 1145675 0 371223 978703 150899 734856 0 860202 0 0 0 0 0 2355502 0 0 0 0 0 1002145 655181 0 892151 1935353 999045 0 411379 91355 760720 928776 1340173 992369 +AALEA(Ala->Thr)GVNKLADTVR MGYG000000142_02316;MGYG000001338_00216;MGYG000002298_01717;MGYG000000200_01192;MGYG000000184_01883;MGYG000004733_00373;MGYG000000216_01233;MGYG000000171_02643;MGYG000001602_01547 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000142_02316 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEAAIAGK MGYG000002171_02571 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002493165|m__MGYG000002171 1.0 COG1256@1|root,COG1256@2|Bacteria,4PKVX@976|Bacteroidetes,2G05N@200643|Bacteroidia,4AWF1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 N 1.0 bacterial-type flagellum assembly 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF4988 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_02571 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEAER MGYG000000013_00650;MGYG000004876_03337;MGYG000001345_01115;MGYG000002218_02990;MGYG000001378_02367;MGYG000002438_02820;MGYG000001313_02483;MGYG000002549_00642;MGYG000001783_01305;MGYG000000042_00184;MGYG000002478_04055;MGYG000003351_01292;MGYG000000355_01906;MGYG000003363_02359;MGYG000000098_03753;MGYG000004797_00961;MGYG000003701_01280;MGYG000004479_01379 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia,4AM3W@815|Bacteroidaceae 0.7777777777777778 976|Bacteroidetes 1.0 C 1.0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000013_00650 0.05555555555555555 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 K00384:trxB, TRR; thioredoxin reductase (NADPH) [EC:1.8.1.9] 1.0 none 1.0 0 0 1328250 0 0 1259674 0 0 0 0 0 0 0 0 0 2552926 0 0 0 0 0 1453473 0 2440307 0 0 0 0 1834488 1871546 2125368 0 1808239 0 0 1976868 0 1876870 0 0 2908293 0 0 1953479 0 0 0 0 2654606 0 0 0 0 0 0 0 0 0 0 2143478 0 1412410 0 0 0 0 0 1773685 1196503 0 2383051 0 0 2031089 0 1298617 0 0 1356392 0 0 1214525 0 0 0 0 1238359 0 0 0 0 1459917 0 0 0 0 0 0 0 1216314 0 0 0 0 1159206 0 0 0 1040027 0 0 1277853 0 1335112 0 0 543189 0 0 497772 0 0 0 0 0 0 0 0 0 737029 0 0 0 0 0 0 0 750178 0 0 0 0 490959 0 635616 0 536082 0 0 735757 0 449978 0 0 0 0 0 1797502 0 0 0 0 0 0 0 0 0 2711135 0 0 0 0 0 1113824 0 0 0 0 0 0 0 2367730 0 0 1078095 0 0 0 0 0 +AALEAERYLSSNC(Carbamidomethyl)LL MGYG000004876_03337 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__|m__MGYG000004876 1.0 COG0492@1|root,COG0492@2|Bacteria,4NEVX@976|Bacteroidetes,2FMNF@200643|Bacteroidia,4AM3W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family 1.0 trxB 1.0 - 1.0 1.8.1.9 1.0 ko:K00384 1.0 ko00450,map00450 1.0 - 1.0 R02016,R03596,R09372 1.0 RC00013,RC02518,RC02873 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004876_03337 1.0 thioredoxin-disulfide reductase. thioredoxin reductase (NADPH). May be identical to EC 1.8.1.10.-!-Formerly EC 1.6.4.5. [thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 K00384:trxB, TRR; thioredoxin reductase (NADPH) [EC:1.8.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4415514 0 0 0 0 270206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175617 0 0 0 0 84303 0 0 0 0 183659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273392 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEAFR MGYG000002065_00912;MGYG000004746_00558;MGYG000003266_00145;MGYG000001718_01732 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG1080@1|root,COG1080@2|Bacteria,2GIZZ@201174|Actinobacteria,4CV00@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) 1.0 ptsP 1.0 - 1.0 2.7.3.9 1.0 ko:K08483 1.0 ko02060,map02060 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko02000 1.0 8.A.7 1.0 - 1.0 - 1.0 PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002065_00912 0.25 phosphoenolpyruvate--protein phosphotransferase. sugar--PEP phosphotransferase enzyme I. Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport.-!-A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme. L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl- [protein] + pyruvate. 1.0 1.0 1.0 1.0 Phosphotransferase system (PTS) 1.0 K08483:ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9] 1.0 none 1.0 0 2861338 0 0 0 0 0 0 0 0 0 0 1864525 0 0 0 886802 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 963336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746266 0 0 0 0 0 0 0 0 0 0 708695 0 0 0 2413121 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3314841 0 0 0 2390590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 687242 0 0 0 0 0 0 0 0 0 0 947593 0 0 0 422822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEAGDQAVIDQITAK MGYG000000074_01748 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1271@1|root,COG1271@2|Bacteria,4NG7U@976|Bacteroidetes,2FMV6@200643|Bacteroidia,22UC3@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Cytochrome bd terminal oxidase subunit I 1.0 cydA 1.0 - 1.0 1.10.3.14 1.0 ko:K00425 1.0 ko00190,ko01100,ko02020,map00190,map01100,map02020 1.0 M00153 1.0 R11325 1.0 RC00061 1.0 ko00000,ko00001,ko00002,ko01000 1.0 3.D.4.3 1.0 - 1.0 - 1.0 Cyt_bd_oxida_I 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01748 1.0 ubiquinol oxidase (electrogenic, proton-motive force generating). cytochrome bd-I oxidase. This terminal oxidase enzyme is unable to pump protons but generates a proton motive force by transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water.-!-The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) is 1.-!-The bd-I oxidase from the bacterium Escherichia coli is the predominant respiratory oxygen reductase that functions under microaerophilic conditions in that organism. cf. EC 7.1.1.3.-!-Formerly EC 1.10.3.14. 2 a ubiquinol + 4 H(+)(in) + O2(in) = 2 a ubiquinone + 4 H(+)(out) + 2 H2O(in). 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways|Two-component system 1.0 K00425:cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEAGVDKLANTVR MGYG000003702_00464;MGYG000000404_00409 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,27I73@186928|unclassified Lachnospiraceae 0.5 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003702_00464 0.5 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 946818 568658 0 1023962 0 0 1135461 0 576179 1568446 629822 733554 0 0 614844 0 261719 0 0 0 0 266916 0 0 0 0 366452 739876 847077 0 0 181012 0 555129 0 0 554611 0 0 416810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 214594 115191 0 160192 0 0 360005 0 198839 194874 327131 351680 0 0 264950 0 384474 0 0 0 0 487804 0 0 0 0 628145 269595 299789 0 0 402374 0 324657 0 0 107057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518497 0 0 0 0 176099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 408454 0 0 0 0 0 0 0 0 0 0 0 0 343004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEAGVN(Deamidated)KLANTVR MGYG000000135_03500 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Murimonas|s__Murimonas intestini|m__MGYG000000135 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000135_03500 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 541968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEAGVNK MGYG000000142_02316;MGYG000002298_01717;MGYG000000200_01192;MGYG000000119_02608;MGYG000000171_02643;MGYG000000135_03500;MGYG000000268_00624;MGYG000001338_00216;MGYG000002312_00711;MGYG000000184_01883;MGYG000004733_00373;MGYG000000216_01233;MGYG000001602_01547 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 0.8461538461538461 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000142_02316 0.07692307692307693 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 3685659 7729937 5160105 1921319 6653888 6073294 1903432 4610712 2722525 3509025 6763879 5060618 6029066 2905826 3997260 5541750 3247561 7288311 3196872 4588754 3709378 7458694 3757257 2485220 3837891 2777680 2509386 5356095 3262344 2667917 3841281 8386702 3778904 3334460 3687755 2469811 2461231 4965552 2176158 19401696 2375969 1450588 4385384 2674752 2612646 2479018 2082986 2080615 3489454 1303449 3153441 1680569 1551797 1760827 2404255 6231816 1777098 2241879 1291629 2314256 3319994 3712117 2028290 1696605 2452584 4996742 3157636 1827059 18556581 7472446 2658767 1532294 2673780 2395682 2306766 3076637 4477452 19582604 6078061 3874922 3195160 7973657 3629296 5992450 3933746 5404072 4758449 4306510 5377593 4881174 6111418 6624880 6477948 2447331 5315926 5781408 5375692 12396012 3881455 5947499 5280017 5326223 6398636 4779420 4764760 6436787 8718411 16579702 8251288 7019563 5731669 3380678 2741001 6162809 2253362 9910010 5284950 2402576 7277739 3107275 2579346 2808268 2472303 4353737 5417172 2825167 4789727 2029175 2002261 5757164 3499154 3399919 1395399 1764838 1959816 4551308 1567589 3948495 1710349 1383715 2706750 4006000 10051567 2510496 17378346 7833316 6586541 1695234 2284097 1662071 1935675 7079378 3249475 14235509 10488857 3998176 4568965 4441521 3142747 3588548 2663201 3647967 4926914 3111757 4888277 3743001 3247030 4786240 2531083 2350972 3164874 1534182 2146226 3774091 4824671 4857017 2831366 3274527 3171292 4275248 2416356 2444781 12442574 14687508 14283133 3504315 3787077 4644980 2060686 6974482 +AALEAGVNKLADTVR MGYG000000142_02316;MGYG000001338_00216;MGYG000002298_01717;MGYG000000200_01192;MGYG000000184_01883;MGYG000004733_00373;MGYG000000216_01233;MGYG000000171_02643;MGYG000001602_01547 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000142_02316 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 596433 0 477452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 425341 0 0 0 349715 295526 0 0 0 785756 1273135 507630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 717819 0 0 0 100687 0 0 0 0 0 0 0 0 0 0 1049266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 322223 0 0 0 0 100276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359304 0 0 0 0 0 0 0 0 0 292352 0 0 0 91603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191074 337003 223162 0 0 0 0 105552 +AALEAGVNQLADTVR MGYG000000217_01904;MGYG000003486_00745;MGYG000000146_01484 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,27I73@186928|unclassified Lachnospiraceae 0.6666666666666666 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000217_01904 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2202079 0 0 0 0 2236833 0 0 0 0 2618727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 787221 0 0 0 0 491159 0 0 0 0 694876 0 280769 0 0 0 0 709183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1631812 0 0 0 0 952135 0 0 0 0 1551198 0 919765 0 0 0 0 1071671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519372 0 0 0 0 0 0 0 0 0 754487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424340 0 0 0 0 0 0 0 0 0 1020105 0 535382 0 0 0 0 335599 0 0 0 +AALEAIYHAGK MGYG000000198_04353 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG1527@1|root,COG1527@2|Bacteria,1U6WZ@1239|Firmicutes,249XD@186801|Clostridia,21YEI@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Archaeal vacuolar-type H -ATPase subunit C 1.0 ntpC 1.0 - 1.0 - 1.0 ko:K02119 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 DUF2764,vATP-synt_AC39 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04353 1.0 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways 1.0 K02119:ATPVC, ntpC, atpC; V/A-type H+/Na+-transporting ATPase subunit C 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEAR MGYG000002040_00491;MGYG000001315_00699 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3WGEY@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 G 0.5 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain 0.5 pgcA 0.5 - 0.5 5.4.2.2,5.4.2.8 0.5 ko:K01835,ko:K01840 0.5 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 0.5 M00114,M00549 0.5 R00959,R01057,R01818,R08639 0.5 RC00408 0.5 ko00000,ko00001,ko00002,ko01000 0.5 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 0.5 - 1.0 - 1.0 - 1.0 GT2 0.5 MGYG000002040_00491 0.5 phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). | phosphomannomutase. phosphoglucose mutase. | phosphomannose mutase. Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.-!-This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.-!-Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate. cf. EC 5.4.2.5.-!-Formerly EC 2.7.5.1. | alpha-D-mannose 1,6-bisphosphate or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.7. alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate. | alpha-D-mannose 1-phosphate = D-mannose 6-phosphate. 0.5 0.5 0.5 0.5 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Purine metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 0.5 K01835:pgm; phosphoglucomutase [EC:5.4.2.2]|K01840:manB; phosphomannomutase [EC:5.4.2.8] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1123795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEATTNALK MGYG000002293_00760 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00760 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 0 0 0 0 0 428092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 446601 0 280885 0 0 0 370112 0 0 0 0 0 0 0 0 0 257843 0 0 0 0 0 130008 0 0 0 0 0 0 0 0 0 0 0 118938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 305585 0 0 0 0 0 0 0 0 0 0 0 619378 0 0 0 372418 388768 369854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2242308 0 0 2026311 0 0 0 0 0 0 0 0 0 0 0 5754299 0 0 0 1374427 6172323 1417366 0 0 0 2263212 0 0 0 0 1997786 0 0 0 0 982710 0 0 243198 0 0 242896 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338797 0 114845 0 0 0 0 0 0 0 0 0 0 0 0 0 144906 +AALEATTNALKEA MGYG000002293_00760 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0776@1|root,COG0776@2|Bacteria,4NSK6@976|Bacteroidetes,2FTWW@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupB 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00760 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 203841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 649419 0 0 0 0 360918 0 0 0 0 258016 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1840009 0 0 0 0 2162047 0 0 0 0 1310635 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEC(Carbamidomethyl)GVNK MGYG000004735_02784 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,27I73@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004735_02784 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 144882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1283891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7711072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEDALELGR MGYG000001315_02988 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,268A2@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Peptidase family M20/M25/M40 1.0 - 1.0 - 1.0 3.5.1.18 1.0 ko:K01439 1.0 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 1.0 M00016 1.0 R02734 1.0 RC00064,RC00090 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_02988 1.0 succinyl-diaminopimelate desuccinylase. - - H2O + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (2S,6S)-2,6- diaminoheptanedioate + succinate. 1.0 1.0 1.0 1.0 Lysine biosynthesis|Metabolic pathways|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01439:dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEDKDSVFYYYQK MGYG000004296_00733 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Ruminococcus_A|s__Ruminococcus_A faecicola|m__MGYG000004296 1.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,25UWG@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 malL 1.0 - 1.0 3.2.1.1,3.2.1.10 1.0 ko:K01176,ko:K01182 1.0 ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973 1.0 - 1.0 R00801,R01718,R01791,R02108,R02112,R06199,R11262 1.0 RC00028,RC00059,RC00077,RC00451 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH13 1.0 - 1.0 Alpha-amylase,DUF3459,Glyco_hydro_42C,Malt_amylase_C 1.0 5.4.99.11|3.2.1.10|3.2.1.20|3.2.1.70|3.2.1.-|2.4.1.- 1.0 GH13_31 1.0 GH13 1.0 GH13_31 1.0 MGYG000004296_00733 1.0 alpha-amylase. | oligo-1,6-glucosidase. glycogenase. | sucrase-isomaltase. Acts on starch, glycogen and related polysaccharides and oligosaccharides in a random manner; reducing groups are liberated in the alpha-configuration.-!-The term 'alpha' relates to the initial anomeric configuration of the free sugar group released and not to the configuration of the linkage hydrolyzed. | This enzyme, like EC 3.2.1.33, can release an alpha-1->6-linked glucose, whereas the shortest chain that can be released by EC 3.2.1.41, EC 3.2.1.142 and EC 3.2.1.68 is maltose.-!-It also hydrolyzes isomaltulose (palatinose), isomaltotriose and panose, but has no action on glycogen or phosphorylase limit dextrin.-!-The enzyme from intestinal mucosa is a single polypeptide chain that also catalyzes the reaction of EC 3.2.1.48.-!-Differs from EC 3.2.1.33 in its preference for short-chain substrates and in its not requiring the 6-glucosylated residue to be at a branch point, i.e. linked at both C-1 and C-4. Endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more (1->4)-alpha-linked D-glucose units. | Hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. 1.0 1.0 1.0 1.0 Galactose metabolism|Starch and sucrose metabolism|Metabolic pathways|Carbohydrate digestion and absorption 1.0 K01176:AMY, amyA, malS; alpha-amylase [EC:3.2.1.1]|K01182:IMA, malL; oligo-1,6-glucosidase [EC:3.2.1.10] 1.0 none 1.0 0 601335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1295181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1544099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEEAEHAAK MGYG000000099_03581 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,2681B@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_03581 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 476160 0 0 431936 0 0 0 0 664333 0 0 0 490106 0 474061 0 0 616554 0 458653 0 0 841959 0 547904 489861 503609 663996 266347 0 0 0 0 491248 599641 477859 580437 0 2025548 0 0 1698936 0 0 0 0 1763372 0 0 0 941896 0 2017587 0 0 153804 0 1749540 0 0 379041 0 1397627 1654609 1608929 273971 1790005 0 0 0 0 1839638 1347355 1708291 1655800 0 708231 0 0 536813 0 0 0 0 457824 0 0 0 372777 0 513699 0 0 487304 0 377774 0 0 489228 0 543773 503224 548786 494263 534061 0 0 0 0 538017 360961 360284 400363 0 507249 0 0 377878 0 0 0 0 451087 0 0 0 216146 0 520396 0 0 253552 0 430896 0 0 452351 0 316522 443852 317685 629416 465730 0 0 0 0 574268 492909 384019 515240 0 431678 0 0 896915 0 0 0 0 416766 0 0 0 572347 0 500758 0 0 1825272 0 427608 0 0 2046891 0 340015 486866 626427 1756001 5713384 0 0 0 0 437053 805943 572512 457607 0 +AALEEAR MGYG000002274_01167;MGYG000004701_01171;MGYG000000099_03676;MGYG000000213_00501;MGYG000001783_00694;MGYG000001300_00868;MGYG000000185_00200 domain d__Bacteria 1.0 COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia,3WHZ5@541000|Ruminococcaceae 0.2857142857142857 186801|Clostridia 0.7142857142857143 T 0.2857142857142857 GHKL domain 0.2857142857142857 - 0.5714285714285714 - 0.8571428571428571 - 0.5714285714285714 - 0.42857142857142855 - 0.5714285714285714 - 0.7142857142857143 - 0.7142857142857143 - 0.7142857142857143 - 0.42857142857142855 - 1.0 - 0.8571428571428571 - 1.0 HATPase_c_5 0.2857142857142857 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 MGYG000002274_01167 0.14285714285714285 - - - - 0.5714285714285714 0.5714285714285714 0.5714285714285714 0.5714285714285714 - 0.5714285714285714 - 0.42857142857142855 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1911139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEEGIVPGGGVAYIR MGYG000004876_02137;MGYG000002478_00380;MGYG000003363_02977;MGYG000004763_01826;MGYG000000243_00634 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia,4AN5D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004876_02137 0.2 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16107744 0 0 0 0 0 0 0 0 0 0 0 0 0 6390357 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6980676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2309748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEFAVAASALK MGYG000002281_02000;MGYG000000196_03698;MGYG000000198_01239;MGYG000000179_03806;MGYG000000243_01648;MGYG000002478_03488;MGYG000000278_03485;MGYG000001688_01694;MGYG000001619_01935;MGYG000000242_02691;MGYG000001065_01869;MGYG000001378_01448;MGYG000001531_02708;MGYG000004797_00251;MGYG000002171_00496 domain d__Bacteria 1.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,21YXD@1506553|Lachnoclostridium 0.5333333333333333 186801|Clostridia 0.5333333333333333 G 1.0 pfkB family carbohydrate kinase 0.5333333333333333 - 0.5333333333333333 - 1.0 2.7.1.45 0.5333333333333333 ko:K00874 0.5333333333333333 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 0.5333333333333333 M00061,M00308,M00631 0.5333333333333333 R01541 0.5333333333333333 RC00002,RC00017 0.5333333333333333 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 0.5333333333333333 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_02000 0.06666666666666667 2-dehydro-3-deoxygluconokinase. KDG kinase. The enzyme shows no activity with 2-dehydro-3-deoxy-D-galactonate. cf. EC 2.7.1.178. 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D- gluconate + ADP + H(+). 0.5333333333333333 0.5333333333333333 0.5333333333333333 0.5333333333333333 Pentose phosphate pathway|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 0.5333333333333333 K00874:kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] 0.5333333333333333 none 1.0 187895 0 227300 340659 0 143072 151067 175872 312808 318071 0 331385 0 171249 152017 108262 232518 0 0 287631 0 94685 0 162026 0 214065 0 0 0 199573 0 0 0 0 0 0 229626 0 337824 0 0 519313 0 185268 334799 305659 331840 483388 0 160187 0 313205 330527 215600 123011 1019579 0 347285 0 99369 889167 325777 0 159874 0 445883 0 212687 0 0 0 0 0 0 350428 181204 780392 0 111028 726018 0 466407 674206 424196 522811 578603 0 517604 0 669111 707899 500466 445665 861752 0 700744 0 614145 788258 311878 0 614725 0 854028 0 749317 0 0 660227 0 0 0 436273 452067 517681 0 360449 519405 0 582285 243121 755238 508755 638170 0 198261 0 772661 666884 410894 528955 480228 0 1123618 0 410187 459914 0 0 458098 0 342516 0 572113 0 0 97299 0 0 0 390513 0 1271994 0 857706 1248618 0 722172 1285939 1053307 1080124 1024861 0 766634 0 1845846 1440546 512657 1090584 1225134 0 1035139 0 771432 2102933 688512 0 1148275 0 3214325 0 1024042 0 0 813547 0 0 0 1111905 849262 +AALEIIEKGPYK MGYG000001415_00853 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG0457@1|root,COG0457@2|Bacteria,4NDX0@976|Bacteroidetes,2FM6J@200643|Bacteroidia,4AMTF@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_2,SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_00853 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 821068 608774 784891 0 978720 1161158 0 0 0 0 855423 987824 0 0 0 867513 856808 1163674 703360 0 1000692 940143 0 1496347 0 0 0 0 0 0 1571781 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41540 0 0 0 0 43608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139296 227852 0 228684 124578 0 0 0 0 165874 76292 0 0 0 131350 71204 230707 55595 0 168657 115809 0 171786 0 0 0 0 0 0 75018 0 0 0 0 0 0 0 0 212244 193828 0 137997 147101 0 0 0 0 212556 256920 0 0 0 216652 189870 77626 105373 0 0 180096 0 235406 0 0 0 0 0 0 497281 0 0 0 0 0 0 0 64966 0 0 0 86487 82440 0 0 0 0 104974 108644 0 0 0 176284 76912 78064 0 0 125578 88025 0 79895 0 0 0 0 0 0 188848 0 0 0 0 +AALEIMK MGYG000001415_00308 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes,2FUJN@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG16623 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Hc1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_00308 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1451514 1415242 1039735 1267191 0 1233900 1427118 1557833 0 1274070 0 1277258 0 1603184 0 871722 1224291 0 950353 0 1521649 1196494 0 1509350 1319222 1464488 0 0 1301702 1081637 957284 0 1123425 2036292 1211525 0 1503146 1036187 346880 0 437891 376222 0 446395 316059 352646 0 613581 0 357619 0 448900 0 483386 363208 0 630364 0 338251 143372 0 368956 0 81664 0 0 321680 338672 213799 0 622597 0 294564 0 369146 258813 352959 115992 392860 417531 0 601242 239404 310623 0 410691 0 199400 0 476075 0 92029 257775 0 317576 0 400517 691103 0 742708 627959 331958 0 0 277086 321045 766257 0 316297 375028 0 0 555517 382961 534679 566369 236281 307697 0 393776 457709 248012 0 360152 0 471495 0 452193 0 504042 460397 0 498580 0 465222 325091 0 336157 308223 299908 0 0 267007 772653 333819 0 171287 801457 674044 0 400792 668370 425221 0 97050 420373 0 0 547542 0 0 0 0 183406 0 106735 0 67483 292790 0 394519 0 0 172062 0 0 210252 0 0 0 621000 298179 0 0 140257 532867 0 0 369072 0 +AALEISQLD MGYG000002494_04127 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1695@1|root,COG1695@2|Bacteria,1RHSE@1224|Proteobacteria,1S255@1236|Gammaproteobacteria,3WV6W@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 K 1.0 Transcriptional regulator PadR-like family 1.0 yqjI 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PadR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04127 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3813423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4259242 0 2722010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEKGVNQLADTVK MGYG000004558_00135 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__|m__MGYG000004558 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004558_00135 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 126838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEKKDYLAK MGYG000000271_02509;MGYG000004271_00777 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000271_02509 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALELAEQR MGYG000001708_01490;MGYG000003360_03404;MGYG000002323_00410;MGYG000002494_02445;MGYG000001465_00016;MGYG000002534_00416;MGYG000003390_02531;MGYG000002535_00001;MGYG000002366_00460;MGYG000001466_00766;MGYG000000235_04517;MGYG000002515_03179;MGYG000002507_04205;MGYG000002477_00163;MGYG000002506_02937;MGYG000000107_05334;MGYG000000093_01116 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0522@1|root,COG0522@2|Bacteria,1MW0U@1224|Proteobacteria,1RQ38@1236|Gammaproteobacteria,3XNVS@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit 1.0 rpsD 1.0 GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 ko:K02986 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S4,S4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001708_01490 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02986:RP-S4, NAM9, rpsD; small subunit ribosomal protein S4 1.0 none 1.0 2337857 2205743 1916139 1958095 1633793 3709488 0 2818455 2196827 0 1084324 0 613531 2147776 1916503 1129562 2115700 0 2091473 2068173 0 3843303 0 3862776 0 1900647 0 0 0 0 1673545 2090143 0 0 2399328 2004717 2209528 0 5143957 5319969 5297233 4273862 3458689 8337264 4560557 4451690 4954582 6248409 1792585 4270769 2467542 5692253 4558984 3279524 5353237 0 7098837 4111080 6486008 8074018 0 5929341 5004308 4943788 3750811 0 5907432 5247235 1977371 4169584 5814507 4513053 4632446 5537980 4390603 5581157 2753198 3131944 3383558 2788417 3462010 5192204 3630471 3645820 2429367 3392978 2291826 1994281 2073976 3756684 2451429 2199389 3227781 0 2781898 3771812 3320456 5281714 0 5198888 3061076 2565158 1841107 0 2867013 2137557 2994046 3382742 3177907 3465114 1707129 3070699 2481486 3248868 3318417 2793916 3432878 2146240 2494664 3386447 3166298 3542231 2039037 3553115 1594141 2188937 2144312 2324997 2599055 2480593 1795960 0 2388397 2240356 3459811 3701176 0 2859615 3135292 2598947 2469342 0 2230562 1974587 1983902 2565645 3490436 3287088 3626183 3639368 2273864 2423075 233289 0 299350 0 0 459219 0 0 0 319784 0 0 0 219445 0 0 0 0 237803 436317 0 187372 0 439845 231161 155282 0 0 200699 0 0 0 377960 0 0 0 0 0 +AALELMK MGYG000001415_00308 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes,2FUJN@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 COG NOG16623 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Hc1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_00308 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1340676 0 0 0 0 0 0 0 0 0 0 0 1754208 0 0 0 0 0 0 0 0 1666472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 615214 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168556 0 0 0 0 0 0 0 0 0 0 0 +AALELSK MGYG000001302.1_01633;MGYG000003469_00939 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 S 1.0 Histone H1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Hc1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_01633 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1165820 1174452 0 0 0 1168870 0 0 0 0 1136251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456962 0 0 0 1068868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1506635 1580827 0 0 0 1328061 0 0 0 0 1149908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1091585 825891 0 0 0 134260 0 0 0 0 1735969 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3049002 2374353 0 0 0 2628526 0 0 0 0 2113926 0 0 0 0 0 0 0 0 0 0 +AALEN(Asn->Ser)GVNQLANTVR MGYG000000133_00304 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000133_00304 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 507296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1027845 0 0 0 0 0 1126373 0 1100153 0 0 0 0 0 0 0 0 957291 0 0 0 0 0 0 0 0 0 0 1129867 0 +AALEN(Deamidated)GVNQLANTVR MGYG000000133_00304 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000133_00304 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 233907 204217 478778 278674 515472 758606 564440 325643 613148 0 522037 374946 339848 844983 604326 354113 358565 0 792985 543885 315713 1066972 0 664125 705332 743132 775867 0 778818 405931 405423 292138 373281 1072859 642634 804222 314282 419356 485424 112890 756950 307125 634562 487252 322302 0 255298 0 509567 358177 729671 282953 636164 487878 319404 0 234664 406799 410576 537801 0 358424 339739 227978 346433 0 0 220653 310049 453698 249293 276405 249168 399355 158525 366786 268385 510729 1056276 0 519282 1091513 667150 302247 261247 0 507551 771844 755034 294550 307124 735280 556032 0 317876 488244 185634 587696 0 260014 410483 323003 401949 0 376403 405717 372601 571244 601414 192771 436294 275450 400452 1236276 685501 251749 648674 847148 436303 896837 468049 1183187 704330 0 492785 469902 339187 645689 610199 335873 423304 0 823799 432820 501826 541470 0 412737 1008548 912469 1482200 0 335237 735726 310121 356455 811611 467247 774165 1000947 644490 573531 7501999 8443837 9421550 11992006 1125681 4195279 12265720 6308452 4777892 0 9687598 7178386 4961703 13684707 1725936 8541995 6608321 0 7635370 2055692 10413807 6145028 0 5227588 7413227 6024337 8706082 0 10965594 1734300 5617947 9793038 17974294 7653833 5321197 9372791 5423424 5401337 +AALENGVN(Deamidated)QLANTVR MGYG000000133_00304 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000133_00304 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 338185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 694267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6486414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALENGVNQLANTVR MGYG000000133_00304 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000133_00304 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 66403 0 0 98059 0 0 0 0 93567 369731 0 728682 0 0 539797 0 0 186722 0 0 0 0 0 0 0 0 437165 253318 293936 0 0 0 0 205008 0 0 0 129761 193009 126356 105336 0 0 0 0 0 82034 0 88055 0 69703 0 84270 0 0 0 0 98244 0 231966 82255 0 0 0 58603 86501 181273 0 0 135817 0 107058 0 0 710976 0 426960 0 0 290278 0 145820 0 604753 96555 0 0 0 194622 0 0 0 0 0 0 145550 0 0 0 0 0 0 581615 0 118087 0 0 0 0 0 0 0 0 0 0 0 0 0 561571 484351 0 0 0 454574 332076 500593 195764 0 0 0 0 0 0 0 0 381635 0 0 0 0 520231 0 0 0 0 0 0 424428 8179976 9584824 6267873 14499588 679990 3610782 9977823 5693563 4109463 8884965 10615200 5189810 5700706 14310969 6529786 8281083 7711180 0 6066354 2209716 9473178 7776191 0 6501980 7792637 5589002 10518191 0 11583436 1408438 6644783 12206871 17057259 8168467 5159916 8932291 4745879 4782831 +AALENQIK MGYG000000271_00657 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 - 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_00657 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01872:AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEPIEAEMTSLNKR MGYG000004797_01140 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia,4ANV3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 ATPase histidine kinase DNA gyrase B HSP90 domain protein 1.0 htpG 1.0 - 1.0 - 1.0 ko:K04079 1.0 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HATPase_c_3,HSP90 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01140 1.0 - - - - 1.0 1.0 1.0 1.0 Protein processing in endoplasmic reticulum|PI3K-Akt signaling pathway|Necroptosis|Antigen processing and presentation|NOD-like receptor signaling pathway|Plant-pathogen interaction|IL-17 signaling pathway|Th17 cell differentiation|Progesterone-mediated oocyte maturation|Estrogen signaling pathway|Pathways in cancer|Prostate cancer|Fluid shear stress and atherosclerosis 1.0 K04079:HSP90A, htpG; molecular chaperone HtpG 1.0 none 1.0 0 0 1684381 2246079 1963154 0 1733668 1287235 0 1738644 0 1570547 1484664 1289473 1056809 1460670 1752440 1540770 1805522 1326346 1472421 1266700 2168185 2009702 1553398 1748540 2363326 2422569 2148029 1308079 2537275 1672838 1759346 0 0 1842228 0 1660429 1160118 0 1623021 1501499 1414800 1593567 1124649 1379651 1229919 1816715 0 0 1357948 1617616 1865812 1173240 3717804 0 1675252 1665215 1658414 2434969 2035073 1388323 1785666 1364937 1282551 1537041 1696705 1250767 1311858 1693281 1497884 0 0 1197358 1276732 1251998 680413 0 660970 526841 944115 860614 891314 584477 677345 598220 0 835584 960798 639261 705592 718208 952533 1974191 763133 685598 423423 675292 1926389 609272 615468 707224 699325 1651076 629640 375179 776126 387168 694003 0 0 580808 585087 811329 65558 0 208631 90964 197859 72196 224089 180878 132739 110575 0 173120 161310 299114 125741 84724 118909 0 117906 67089 221187 219307 0 0 191464 73503 112212 0 83154 0 0 445436 176634 0 0 0 65040 0 576132 0 657918 682195 1093042 786018 612257 830651 673607 319707 0 513225 1182252 461038 595529 853140 780164 1526107 766875 867225 406874 673273 1439415 789441 686770 884040 1011581 1343561 871651 598329 662542 637806 473128 0 0 720071 735218 616651 +AALEPIESEMANLNNR MGYG000000243_01589 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia,4ANV3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 ATPase histidine kinase DNA gyrase B HSP90 domain protein 1.0 htpG 1.0 - 1.0 - 1.0 ko:K04079 1.0 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HATPase_c_3,HSP90 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01589 1.0 - - - - 1.0 1.0 1.0 1.0 Protein processing in endoplasmic reticulum|PI3K-Akt signaling pathway|Necroptosis|Antigen processing and presentation|NOD-like receptor signaling pathway|Plant-pathogen interaction|IL-17 signaling pathway|Th17 cell differentiation|Progesterone-mediated oocyte maturation|Estrogen signaling pathway|Pathways in cancer|Prostate cancer|Fluid shear stress and atherosclerosis 1.0 K04079:HSP90A, htpG; molecular chaperone HtpG 1.0 none 1.0 0 0 863177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 624371 0 0 0 0 553800 0 0 0 0 449333 0 0 0 0 897007 0 0 0 0 634441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366176 0 0 0 0 531639 0 0 0 0 0 0 0 0 0 0 0 0 579790 0 0 0 0 0 0 0 0 0 0 0 0 0 0 786699 0 0 0 0 468657 0 0 0 0 307532 0 0 0 0 710500 0 0 0 0 533486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250721 0 0 0 0 0 0 0 0 0 197745 0 0 0 0 0 0 0 0 0 0 0 0 180082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190629 0 0 0 0 283948 +AALEPIET(Thr->Ala)EMTSLNKR MGYG000002478_03790 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0326@1|root,COG0326@2|Bacteria,4NDXZ@976|Bacteroidetes,2FMED@200643|Bacteroidia,4ANV3@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 T 1.0 ATPase histidine kinase DNA gyrase B HSP90 domain protein 1.0 htpG 1.0 - 1.0 - 1.0 ko:K04079 1.0 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HATPase_c_3,HSP90 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_03790 1.0 - - - - 1.0 1.0 1.0 1.0 Protein processing in endoplasmic reticulum|PI3K-Akt signaling pathway|Necroptosis|Antigen processing and presentation|NOD-like receptor signaling pathway|Plant-pathogen interaction|IL-17 signaling pathway|Th17 cell differentiation|Progesterone-mediated oocyte maturation|Estrogen signaling pathway|Pathways in cancer|Prostate cancer|Fluid shear stress and atherosclerosis 1.0 K04079:HSP90A, htpG; molecular chaperone HtpG 1.0 none 1.0 1559825 0 0 0 0 1524178 0 0 1955581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1438000 0 0 1139463 0 0 0 0 0 0 0 0 0 1598069 0 0 0 0 0 1514761 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190434 0 0 0 0 0 0 0 156012 0 0 0 0 0 0 0 0 0 0 0 0 71594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEQGV(Val->Ser)NK MGYG000000164_00892 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,27I73@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000164_00892 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 1899384 0 0 0 0 0 0 0 1404149 3238049 0 0 0 0 2872995 0 0 0 0 3096662 0 1562767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1230585 0 0 0 0 0 0 0 2083661 2674743 0 0 0 0 6135073 0 0 0 0 5352843 0 2173397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 539885 0 0 0 0 0 0 0 436728 1102302 0 0 0 0 0 0 0 0 0 1133906 0 535059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194904 965777 0 0 0 0 433986 0 0 0 0 532433 0 0 0 0 0 0 0 0 0 0 +AALEQGVNK MGYG000000164_00892 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,27I73@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000164_00892 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 5944543 0 0 0 3053440 2058754 6771081 5034750 5975450 5630879 1842532 0 5760653 4572672 5601408 0 2336993 0 4338692 0 8118653 3803162 0 1675241 7359477 4671494 3917689 0 4519436 3682607 0 0 0 4338789 4582886 5664245 4873799 0 187648 0 0 0 1094053 476146 491127 281282 368351 457084 524367 0 474526 301141 220901 0 505741 0 503804 0 627576 419837 0 506999 241451 318642 289613 0 684236 603044 0 0 0 386016 535986 340265 0 0 373379 0 0 0 0 0 518117 576918 0 275093 0 0 565465 338372 547552 0 0 0 1126058 0 482803 0 0 0 769096 242253 294816 0 0 277071 0 0 0 329145 776101 260874 265747 0 937261 0 0 0 969222 789289 0 0 875272 1067769 194112 0 668478 951431 0 0 749277 0 940860 0 0 1585453 0 2493695 575713 0 0 0 1750141 214447 0 0 0 584432 165911 0 239228 0 221621 0 0 0 0 98278 0 255920 192311 0 0 0 295873 799413 0 0 0 0 246900 0 236689 127673 0 0 562233 263203 232522 0 0 253317 0 0 0 244763 373214 577578 147788 0 +AALERGVNQLADTVR MGYG000002835_00808 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter sp900543115|m__MGYG000002835 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,27I73@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002835_00808 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 798171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALESGVNQLANTVR MGYG000000301_00959;MGYG000000806_01492;MGYG000002966_01600;MGYG000003012_02207 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000301_00959 0.25 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 1215714 0 64015 426063 0 0 215415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271427 156225 278380 0 0 0 377080 206643 402815 296942 482325 0 0 0 0 0 0 0 0 0 0 1063940 1115630 0 1328810 0 0 0 126913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83291 79337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1024923 1498604 1198534 1282092 0 1231923 2115695 1303483 0 2176092 2091383 0 733856 1972730 0 1108736 0 0 1483756 0 1317374 1987405 0 1910820 1215478 0 1828941 0 2076430 516215 1386570 2016197 1980139 1605960 1252015 0 0 1243888 +AALESTLAAITESLK MGYG000003372_03358;MGYG000002494_02496;MGYG000002515_03637;MGYG000002535_04014;MGYG000002477_01000;MGYG000002506_03710;MGYG000002534_04602 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,3XPW4@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupA 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006323,GO:0006351,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:1990104,GO:1990178,GO:2001141 1.0 - 1.0 ko:K03530,ko:K05787 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003372_03358 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta|K05787:hupA; DNA-binding protein HU-alpha 1.0 none 1.0 574894 0 470412 0 0 167244 414561 0 381275 0 0 0 0 0 968570 0 410072 0 0 0 0 9832977 0 109966 0 127440 0 0 0 0 0 420387 354438 10971154 0 0 668020 319409 17077201 0 0 0 0 12233989 70349600 0 14899469 0 0 0 0 0 54745225 0 89466696 0 0 0 0 14077772 0 125006746 0 330452 0 0 0 0 0 27905187 436120 12756794 0 0 29549197 45371803 1219681 0 1756954 0 0 17040236 6433458 0 0 0 0 0 0 0 0 0 403644 0 0 0 0 724937 0 0 0 0 0 0 0 0 0 0 0 115907 0 0 0 0 1092255 0 0 0 0 0 0 0 8558344 0 0 0 0 0 4949463 0 0 0 0 0 0 0 0 5562030 0 4906365 0 0 0 0 0 10594939 0 13883784 0 0 7482466 6080537 0 0 1601788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3602639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALESTLAAITESLKEGDAVQLVGFGTFK MGYG000003372_03358;MGYG000002494_02496;MGYG000002506_03710 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,3XPW4@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupA 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006323,GO:0006351,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:1990104,GO:1990178,GO:2001141 1.0 - 1.0 ko:K03530,ko:K05787 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003372_03358 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta|K05787:hupA; DNA-binding protein HU-alpha 1.0 none 1.0 0 0 0 0 0 5372714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 26974770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6475086 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4554182 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALETAVANVESAK MGYG000002478_01778;MGYG000000243_02508 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,2FN62@200643|Bacteroidia,4AP66@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family 1.0 - 1.0 - 1.0 - 1.0 ko:K03585 1.0 ko01501,ko01503,map01501,map01503 1.0 M00646,M00647,M00699,M00718 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 1.0 2.A.6.2,8.A.1.6 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01778 0.5 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|Cationic antimicrobial peptide (CAMP) resistance 1.0 K03585:acrA, mexA, adeI, smeD, mtrC, cmeA; membrane fusion protein, multidrug efflux system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1761377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1102700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423543 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALETGVNK MGYG000000212_00038 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000212_00038 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599910 0 2603888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8675022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2423335 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3309299 0 0 0 0 0 0 0 0 0 +AALETGVNKLADTVR MGYG000000212_00038 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000212_00038 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALETQIK MGYG000004271_00888 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain 1.0 alaS 1.0 - 1.0 6.1.1.7 1.0 ko:K01872 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03038 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DHHA1,tRNA-synt_2c,tRNA_SAD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00888 1.0 alanine--tRNA ligase. alanyl-tRNA synthetase. - ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01872:AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2278146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1729904 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALETVK MGYG000000243_01974 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0049@1|root,COG0049@2|Bacteria,4NEEM@976|Bacteroidetes,2FNKP@200643|Bacteroidia,4ANTK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA 1.0 rpsG 1.0 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02992 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01974 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02992:RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3325777 0 0 0 0 6308235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3075642 0 0 0 0 0 0 0 0 0 1635795 0 0 0 0 0 0 0 0 0 0 +AALEV(Val->Thr)GVNKLADTVR MGYG000002202_00450 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Massilistercora|s__Massilistercora timonensis|m__MGYG000002202 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,21YIV@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000002202_00450 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALEVK MGYG000001623_01332;MGYG000002528_02478;MGYG000004594_00959;MGYG000004667_00970;MGYG000001615_00145;MGYG000000233_02503;MGYG000000325_02351;MGYG000002098_00511;MGYG000004087_01282;MGYG000002590_00564;MGYG000004891_00190;MGYG000000378_00784;MGYG000002247_01703;MGYG000000179_00100;MGYG000000074_00389;MGYG000001564_02842;MGYG000000028_00797;MGYG000000217_00686;MGYG000002212_01829;MGYG000001577_00663;MGYG000004380_01725;MGYG000000198_00250;MGYG000000118_00274;MGYG000001423_03022;MGYG000002139_00077;MGYG000003291_00558;MGYG000000312_02404;MGYG000000121_02531;MGYG000001754_01214;MGYG000001338_02151;MGYG000001646_00500;MGYG000000184_00575;MGYG000003486_02360;MGYG000004879_02866;MGYG000000202_02337;MGYG000002082_01062;MGYG000000087_02439 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,21XUV@1506553|Lachnoclostridium 0.1891891891891892 186801|Clostridia 0.9459459459459459 G 0.918918918918919 Belongs to the PEP-utilizing enzyme family 0.7027027027027027 ppdK 0.918918918918919 - 0.9459459459459459 2.7.9.1 0.918918918918919 ko:K01006 0.918918918918919 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.918918918918919 M00169,M00171,M00172,M00173 0.918918918918919 R00206 0.918918918918919 RC00002,RC00015 0.918918918918919 ko00000,ko00001,ko00002,ko01000 0.918918918918919 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.918918918918919 - 1.0 - 1.0 - 1.0 GT1 0.8918918918918919 MGYG000001623_01332 0.02702702702702703 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.918918918918919 0.918918918918919 0.918918918918919 0.918918918918919 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 0.918918918918919 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 0.918918918918919 none 1.0 0 2448713 1075654 924437 3170530 863584 0 0 0 0 1856956 1263285 2762666 0 0 2330746 0 0 0 1816210 0 1218899 3094312 1258963 920299 0 1178458 3362842 750027 0 0 0 917961 0 0 0 0 1389487 0 7731515 2930426 1533923 2585713 2877244 0 0 0 0 0 0 3337023 0 0 2833560 0 2659923 2542523 2027121 0 0 2120687 2768642 1941737 0 0 0 2381358 0 0 0 0 0 0 0 0 0 0 10143358 1255398 2393586 1243542 1976618 0 0 0 0 0 1863714 1902505 0 0 2713854 0 275561 2432960 0 0 0 1670137 0 3068078 0 1942743 2434452 2236913 0 0 0 0 0 0 0 0 0 0 0 2260378 1531974 3057656 1150389 0 0 0 0 3300331 2041349 1593268 0 0 0 0 1129836 2484634 1655558 0 0 246074 2849415 667642 0 0 0 1695951 0 0 0 0 0 0 0 0 0 0 0 4226050 2700541 0 1669786 0 0 0 0 5533961 3036012 2482063 0 0 0 0 1385499 1423969 0 0 1930979 2106952 2580342 2194208 0 0 2440038 3602680 0 0 9380026 7963113 0 0 0 0 5094990 +AALEYGLK MGYG000001410_00799;MGYG000003170_00073 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella 1.0 COG0100@1|root,COG0100@2|Bacteria,1RD0A@1224|Proteobacteria,2VR8I@28216|Betaproteobacteria,4PQYJ@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001410_00799 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264311 0 0 0 0 427742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 329264 0 0 0 0 87699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830504 0 0 0 0 715467 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1206225 0 0 0 0 1407383 0 0 0 +AALFGQTC(Carbamidomethyl)FNPGEAK MGYG000000262_02304;MGYG000000087_01966 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,25VA2@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 F 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02304 0.5 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 0 499747 0 0 0 328477 0 0 0 0 0 0 0 0 0 0 0 0 619414 0 0 0 0 0 616510 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1311338 0 0 0 378240 0 0 0 1044388 0 0 0 0 0 0 0 0 1670369 1755160 780601 776619 0 0 1284384 0 0 0 0 0 0 0 0 1730783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALFGQTC(Carbamidomethyl)YNPGEAK MGYG000000198_04024 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,21ZAZ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 F 1.0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate 1.0 glpK 1.0 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 1.0 2.7.1.30 1.0 ko:K00864 1.0 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 1.0 - 1.0 R00847 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N,MazG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_04024 1.0 glycerol kinase. glycerokinase. Glycerone and L-glyceraldehyde can act as acceptors.-!-UTP (and, in the case of the Saccharomyces cerevisiae enzyme, ITP and GTP) can act as donors. ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways|PPAR signaling pathway|Plant-pathogen interaction 1.0 K00864:glpK, GK; glycerol kinase [EC:2.7.1.30] 1.0 none 1.0 0 0 0 0 0 0 0 251917 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 154973 167940 396806 0 0 0 157124 0 0 0 0 0 0 0 0 0 0 0 0 0 283633 0 0 0 0 0 0 0 0 0 0 0 318440 0 0 0 0 0 3003512 1004842 1616848 0 0 0 1821481 1434110 0 0 658883 0 0 2276274 0 0 1182325 0 2886250 4409782 2619605 0 0 0 0 2086617 0 0 0 0 0 0 1250047 3401201 0 0 2388732 1040733 272129 418012 318066 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270301 295843 0 0 0 0 0 0 0 0 0 0 0 0 338321 408090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALFLGR MGYG000000249_01571 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG1196@1|root,COG1554@1|root,COG1196@2|Bacteria,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,248K8@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Psort location 1.0 - 1.0 - 1.0 3.2.1.51 1.0 ko:K15923 1.0 ko00511,map00511 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH95 1.0 - 1.0 CHB_HEX_C_1,FIVAR,Glyco_hyd_65N_2,Laminin_G_3,NPCBM 1.0 - 1.0 GH95 1.0 GH95 1.0 GH95 1.0 MGYG000000249_01571 1.0 alpha-L-fucosidase. Alpha-L-fucoside fucohydrolase. - an alpha-L-fucoside + H2O = an alcohol + L-fucose. 1.0 1.0 1.0 1.0 Other glycan degradation 1.0 K15923:AXY8, FUC95A, afcA; alpha-L-fucosidase 2 [EC:3.2.1.51] 1.0 none 1.0 420165 0 0 0 0 0 0 114373 0 0 0 0 0 0 0 0 0 0 0 282205 0 0 0 0 0 288875 0 0 0 0 0 0 0 0 214438 0 256044 0 1213023 0 0 0 0 0 0 1002081 0 0 0 0 0 0 0 0 0 0 0 1081647 0 0 0 0 0 1145383 0 0 0 0 0 0 0 0 1128727 0 1127833 0 369020 0 0 0 0 0 0 456224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93590 0 0 0 0 0 0 621956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353977 0 0 0 0 0 0 0 0 677798 0 106316 0 93968 0 0 0 0 0 0 334394 0 0 0 0 0 0 0 0 0 0 0 385602 0 0 0 0 0 280443 0 0 0 0 0 0 0 0 400079 0 78064 0 +AALFVVDVQK MGYG000000074_02444 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia,22U1D@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02444 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 255647 0 0 294759 0 0 0 0 0 0 0 0 0 257756 0 0 0 0 255206 0 0 0 0 0 256475 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236416 0 0 0 0 0 0 0 0 0 284279 354602 0 201755 0 0 0 0 0 0 0 271633 0 0 0 0 0 0 0 0 0 0 0 0 0 640301 0 0 773826 0 0 0 0 0 0 0 555102 0 449918 748304 0 411730 0 410761 0 0 0 0 0 640403 0 0 0 0 0 0 0 0 0 0 0 0 0 387875 0 0 246978 0 0 0 0 0 0 0 160937 0 299502 268114 0 292202 0 308998 0 0 0 0 0 393987 0 0 0 0 0 0 0 0 0 0 0 0 0 1013892 0 0 1090534 0 0 0 0 0 0 0 566070 0 742584 1405327 0 660895 0 673540 0 0 0 0 0 1415078 0 0 0 0 0 0 0 0 +AALGAAIAVIGAGIGIGK MGYG000002478_03336;MGYG000000042_02496 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0636@1|root,COG0636@2|Bacteria,4NURW@976|Bacteroidetes,2FTSZ@200643|Bacteroidia,4ARQC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation 1.0 atpE 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 - 1.0 ko:K02110 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_03336 0.5 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02110:ATPF0C, atpE; F-type H+-transporting ATPase subunit c 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGAEGC(Carbamidomethyl)GK MGYG000000099_02237 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia,267QW@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 kdd 1.0 - 1.0 1.4.1.11 1.0 ko:K18012 1.0 ko00310,map00310 1.0 - 1.0 R03349 1.0 RC00888 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_02237 1.0 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K18012:kdd; L-erythro-3,5-diaminohexanoate dehydrogenase [EC:1.4.1.11] 1.0 none 1.0 1288058 0 645195 1822858 524263 585923 1078236 797014 843744 705112 560244 491299 638718 949443 913064 376292 585014 0 503657 465056 901543 264337 0 446934 1983339 921081 910974 0 1066899 777209 318250 395277 0 548750 990983 1139330 762161 454773 6072879 0 3094701 8000974 4036245 3630886 8403513 8806846 8058837 8535494 4463405 5447097 3193657 8307838 7650299 3575021 5719802 0 5783080 7186881 4840509 2947746 0 3163132 5169207 8137773 8188210 0 6258108 6688909 3338131 4547721 4986431 9930464 7853039 9127173 8473877 4758175 415135 0 109484 1145900 0 453678 324024 192708 966654 842187 279400 784016 0 824560 558948 275565 898382 0 898870 1424721 825284 426394 0 0 582773 396445 554153 0 772126 1017139 0 121071 449399 372853 680411 680777 611096 177640 986450 0 643703 563970 582793 413683 1260652 609901 719360 493050 645071 411619 449056 847240 970362 513844 659932 0 694667 775682 96789 680848 0 521952 966754 1121421 687132 0 604245 592910 923014 530344 511051 2360319 714109 708481 849748 725709 4622026 0 2956435 1380557 1317254 1726531 143197 2108014 2884357 2624098 490272 220365 1094174 1285787 3009187 2764661 1982919 0 1050102 3442671 4460114 2276397 0 2630795 2930773 2457780 4642862 0 655612 2359722 3444958 341737 626774 0 566519 2826498 3632512 3736226 +AALGAEGC(Cys->Xle)GK MGYG000000099_02237 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia,267QW@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 kdd 1.0 - 1.0 1.4.1.11 1.0 ko:K18012 1.0 ko00310,map00310 1.0 - 1.0 R03349 1.0 RC00888 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_02237 1.0 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K18012:kdd; L-erythro-3,5-diaminohexanoate dehydrogenase [EC:1.4.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4095174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3036243 0 0 0 0 0 0 0 3109711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4224151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGAEGIGK MGYG000002926_00666;MGYG000002882_00083;MGYG000002794_00765;MGYG000002156_01166;MGYG000001733_00674;MGYG000002720_00859;MGYG000004196_01675;MGYG000002143_01957;MGYG000002953_01591;MGYG000004475_00754 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia 0.9 186801|Clostridia 1.0 C 0.9 alcohol dehydrogenase 0.9 kdd 0.9 - 1.0 1.4.1.11 0.9 ko:K18012 0.9 ko00310,map00310 0.9 - 0.9 R03349 0.9 RC00888 0.9 ko00000,ko00001,ko01000 0.9 - 1.0 - 1.0 - 1.0 ADH_zinc_N 0.9 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_00666 0.1 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 0.9 0.9 0.9 0.9 Lysine degradation 0.9 K18012:kdd; L-erythro-3,5-diaminohexanoate dehydrogenase [EC:1.4.1.11] 0.9 none 1.0 7786031 4881187 2142091 6583164 0 6341504 10196745 5802658 6492259 5797016 3291419 2197349 0 7470173 9084159 0 3089399 4910174 4417787 6857523 3526475 5525089 1119715 6469708 7767893 6629312 5539174 1274753 7226843 670794 223757 1437193 2148472 8895158 5892504 7954896 9119600 1983244 4068937 1472861 157287 3261488 1319445 1322767 2745168 3701857 4297053 3368432 749601 2041539 0 2878114 2604882 1189616 739828 0 3798389 3614676 2338158 1188856 0 1662434 2046842 0 3785645 0 0 2351852 1332149 1867823 1133597 0 5050203 3880459 4686097 1834085 10990613 0 5697558 10403527 0 4690880 10138221 10180843 9170481 9613624 3479704 5555645 262374 10547213 10664676 3952813 10187502 0 11679016 9029191 8074356 7072124 0 4989218 8642475 8284346 10370479 0 7919161 9506623 3777048 6047824 7569573 9025027 9775128 9611238 9636033 0 4158472 9326963 5634913 5224381 5809353 6838185 7640814 5633356 5481539 7014856 4335812 4534315 3643483 5040721 4516130 4726575 6020958 0 5222976 5157679 3026932 5589441 1070658 6215581 4711685 4504617 4750390 1920198 8644235 4834608 4658206 8996009 5806005 4701287 5632823 4587138 4053297 6420853 1432755 1807772 418315 1150586 2493295 1038501 210232 1345845 560924 1836980 915906 3162658 828222 806423 835129 0 1938111 518631 1358020 0 0 1244845 603119 925902 345160 1302779 1115478 0 995715 0 378308 3211813 504277 1354897 2198440 1732283 639238 721143 +AALGAEGIGKDVTM(Oxidation)IIGN(Deamidated)GYTK MGYG000002926_00666;MGYG000002794_00765;MGYG000002156_01166;MGYG000001733_00674;MGYG000002720_00859;MGYG000004475_00754 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 kdd 1.0 - 1.0 1.4.1.11 1.0 ko:K18012 1.0 ko00310,map00310 1.0 - 1.0 R03349 1.0 RC00888 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_00666 0.16666666666666666 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K18012:kdd; L-erythro-3,5-diaminohexanoate dehydrogenase [EC:1.4.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 160962 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGAEGIGKDVTMIIGN(Deamidated)GYTK MGYG000002926_00666;MGYG000002794_00765;MGYG000002156_01166;MGYG000001733_00674;MGYG000002720_00859;MGYG000004475_00754 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 kdd 1.0 - 1.0 1.4.1.11 1.0 ko:K18012 1.0 ko00310,map00310 1.0 - 1.0 R03349 1.0 RC00888 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_00666 0.16666666666666666 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K18012:kdd; L-erythro-3,5-diaminohexanoate dehydrogenase [EC:1.4.1.11] 1.0 none 1.0 4654951 3371092 0 0 0 2286445 0 2772641 0 2415727 0 0 0 2970278 0 0 0 0 0 0 0 2596687 0 2100256 2235844 2530740 0 0 0 0 0 0 0 3263831 0 0 2617183 0 699661 506081 0 0 0 475119 0 1008094 0 1032309 0 0 0 597281 0 0 0 0 0 0 0 289587 0 325311 599399 1258195 0 0 0 0 0 0 0 696118 0 0 887259 0 0 1783387 0 0 0 1417233 0 0 0 3991263 0 0 0 0 0 0 0 0 0 0 0 0 0 914036 0 3124131 0 0 0 0 0 0 0 0 0 0 0 0 414205 603314 0 0 0 1423018 0 1930855 0 1339963 0 0 0 1738111 0 0 0 0 0 0 0 3111988 0 0 3998446 764598 0 0 0 0 0 0 0 4547513 0 0 0 0 114680 0 0 0 0 364407 0 227406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGAEGIGKDVTMIIGNGYTK MGYG000002926_00666;MGYG000002794_00765;MGYG000002156_01166;MGYG000001733_00674;MGYG000002720_00859;MGYG000004475_00754 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0604@1|root,COG0604@2|Bacteria,1TQ4W@1239|Firmicutes,249C7@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 alcohol dehydrogenase 1.0 kdd 1.0 - 1.0 1.4.1.11 1.0 ko:K18012 1.0 ko00310,map00310 1.0 - 1.0 R03349 1.0 RC00888 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_00666 0.16666666666666666 L-erythro-3,5-diaminohexanoate dehydrogenase. - - (3S,5S)-3,5-diaminohexanoate + H2O + NAD(+) = (5S)-5-amino-3-oxohexanoate + H(+) + NADH + NH4(+). 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K18012:kdd; L-erythro-3,5-diaminohexanoate dehydrogenase [EC:1.4.1.11] 1.0 none 1.0 6556707 0 2266985 2578748 0 3183344 3685324 0 2977567 0 0 0 0 4833419 0 0 0 0 0 0 0 4228683 0 0 2799714 45171 0 0 0 0 0 0 0 6960526 0 0 13548155 5335117 1492740 0 0 2489680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1000655 0 826633 0 0 0 0 0 0 0 0 0 0 2549242 2109193 0 0 6898869 259107 0 6337894 0 0 5036483 0 0 0 0 5677933 0 0 0 0 0 0 0 0 0 0 4026580 14951269 0 0 0 0 0 0 0 0 0 0 0 7214218 1734297 0 2098785 3106415 0 0 3223076 0 0 0 0 0 0 946219 0 0 0 0 0 0 0 0 0 2651544 0 2853934 0 0 0 0 0 0 0 2658829 0 0 3770228 0 0 0 4383757 0 0 0 0 0 525220 0 0 0 0 6219359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGAFASYK MGYG000001356_00742 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter sp000177015|m__MGYG000001356 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001356_00742 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10200:ngcE; N-acetylglucosamine transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135924 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1586368 0 0 0 0 0 0 0 0 0 +AALGAGVDKLANTVR MGYG000000245_00416;MGYG000002492_02075;MGYG000004271_02056;MGYG000000489_01318;MGYG000000271_00294 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000245_00416 0.2 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 931140 980344 466432 986027 329161 651585 1076470 932549 984334 990027 1228604 0 709417 0 0 659631 907242 0 301733 521672 833127 578494 556366 568863 0 491189 896341 404311 811876 1623555 0 0 489707 0 0 742373 882592 415296 506692 366469 1010167 0 1404138 0 0 516215 0 0 978412 475300 634544 0 0 882653 262469 4953542 193287 0 419089 0 3542135 481119 0 369488 348433 3513764 384696 374452 0 0 1583539 0 0 522846 0 726470 2285405 2636548 4252975 2013459 2123811 2004079 2065679 2140584 2069617 1788040 2745556 3204047 2534893 0 0 3553420 2073326 1623205 1799095 1865459 1647148 1782024 2004717 1993696 0 2376346 2080165 2725671 2000417 2556529 0 0 4663076 0 0 1926755 2197663 4221696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588991 428325 483386 119910 309899 655929 568701 244912 512540 614387 145390 1573104 592851 0 0 386359 1022145 652592 780632 638055 441657 463703 703999 668918 0 286389 468194 994554 0 541007 0 0 458286 0 0 474885 454625 436919 +AALGAGVGADALDKAPQLTAESK MGYG000000187_00358 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp003537285|m__MGYG000000187 1.0 COG4677@1|root,COG5263@1|root,COG4677@2|Bacteria,COG5263@2|Bacteria,1UKUC@1239|Firmicutes,25G3Y@186801|Clostridia 1.0 186801|Clostridia 1.0 M 1.0 repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Beta_helix,CW_binding_1,Laminin_G_3 1.0 - 1.0 PL9_1 1.0 PL9 1.0 PL9_1 1.0 MGYG000000187_00358 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 861856 0 0 0 0 712215 0 0 0 0 570310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGAHTPHDK MGYG000002619_00997;MGYG000002610_01679;MGYG000001300_01680;MGYG000002040_01831;MGYG000003166_01503 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4,Fer4_10,Fer4_4,Fer4_7,Fer4_8,Fer4_9,MTHFR_C,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002619_00997 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03615:rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 722850 0 88259 0 0 676940 0 0 0 451874 591527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 745134 0 887966 0 0 996670 0 0 0 721602 228658 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302982 0 185780 0 0 604826 0 0 0 351663 883074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546042 0 254355 0 0 70225 0 0 0 326014 897841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 895968 0 172921 0 0 1047116 0 0 0 125373 466191 0 0 0 0 0 0 0 0 0 0 +AALGASESMR MGYG000002549_04076 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides caccae|m__MGYG000002549 1.0 COG0521@1|root,COG0521@2|Bacteria,4NKEX@976|Bacteroidetes,2FQAE@200643|Bacteroidia,4AK9S@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 COG NOG26372 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SusD-like,SusD-like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_04076 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3974433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGDLTHVDAEK MGYG000002494_04209 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0614@1|root,COG0614@2|Bacteria,1NVK4@1224|Proteobacteria,1RRND@1236|Gammaproteobacteria,3ZMKD@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 P 1.0 periplasmic binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K02016 1.0 ko02010,map02010 1.0 M00240 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.14 1.0 - 1.0 - 1.0 Peripla_BP_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04209 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K02016:ABC.FEV.S; iron complex transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1093030 0 841854 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGEAIAAVFSLAGAK MGYG000000074_01368 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG2195@1|root,COG2195@2|Bacteria,4NG8I@976|Bacteroidetes,2FM0V@200643|Bacteroidia,22U4S@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Peptidase family M20/M25/M40 1.0 pepD_2 1.0 - 1.0 - 1.0 ko:K01270 1.0 ko00480,ko01100,map00480,map01100 1.0 - 1.0 R00899,R04951 1.0 RC00096,RC00141 1.0 ko00000,ko00001,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01368 1.0 - - - - 1.0 1.0 1.0 1.0 Glutathione metabolism|Metabolic pathways 1.0 K01270:pepD; dipeptidase D [EC:3.4.13.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1317355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8839409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGFK MGYG000000038_00759;MGYG000000171_02843;MGYG000000201_03874;MGYG000001617_01407;MGYG000001338_03374;MGYG000000142_00172;MGYG000000251_00063;MGYG000001315_01206;MGYG000002298_03446;MGYG000004733_01212;MGYG000002966_00551;MGYG000000200_01983 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.8333333333333334 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000000038_00759 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550889 774230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80494 0 0 0 0 0 +AALGIANVIVNSK MGYG000002485_02147 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0751@1|root,COG0751@2|Bacteria,378Q2@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 J 1.0 glycyl-tRNA synthetase beta 1.0 glyS 1.0 - 1.0 6.1.1.14 1.0 ko:K01879 1.0 ko00970,map00970 1.0 M00360 1.0 R03654 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 DALR_1,tRNA_synt_2f 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_02147 1.0 glycine--tRNA ligase. glycyl-tRNA synthetase. - ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01879:glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 731209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1091200 0 696013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGLAK MGYG000002528_00255 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,267VM@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 1.0 gpsA 1.0 - 1.0 1.1.1.94 1.0 ko:K00057 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00842,R00844 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 G3P_acyltransf,NAD_Gly3P_dh_C,NAD_Gly3P_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00255 1.0 glycerol-3-phosphate dehydrogenase [NAD(P)(+)]. L-glycerol-3-phosphate:NAD(P) oxidoreductase. The enzyme from Escherichia coli shows specificity for the B side of NADPH. (1) NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH. (2) NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00057:gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 110972 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGLDIDLK MGYG000002517_01313 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate 1.0 punA 1.0 - 1.0 2.4.2.1 1.0 ko:K03783 1.0 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 1.0 - 1.0 R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 1.0 RC00033,RC00063,RC00122 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glu_synthase,PNP_UDP_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01313 1.0 purine-nucleoside phosphorylase. PNPase. Specificity not completely determined.-!-Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5. (1) a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha- D-ribose 1-phosphate. (2) a purine 2'-deoxy-D-ribonucleoside + phosphate = 2-deoxy-alpha-D- ribose 1-phosphate + a purine nucleobase. 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Nicotinate and nicotinamide metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K03783:punA, PNP; purine-nucleoside phosphorylase [EC:2.4.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102190 0 0 0 77033 0 0 0 0 0 0 0 0 0 0 72231 0 0 0 0 0 62126 0 0 0 0 0 0 0 0 0 80496 0 93787 0 582286 0 0 632465 0 0 0 590077 633373 0 0 0 0 621543 679191 0 499827 0 570425 721628 0 0 0 0 526727 649525 648655 0 0 0 0 0 0 0 690972 471555 714691 0 353933 0 0 0 0 0 0 0 209576 0 0 0 0 549790 546023 0 320487 0 394642 304848 0 0 0 0 341521 334890 423871 0 0 0 0 0 0 0 215649 300329 0 0 +AALGPYKGGLR MGYG000003686_00696;MGYG000004482_01468 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__ER4 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,2N73E@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdh 1.0 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0071704,GO:1901564 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003686_00696 0.5 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 434138 0 0 0 0 0 0 0 826635 0 0 0 0 1394607 0 0 0 0 1150362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGQIEK MGYG000000201_01679 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066145|m__MGYG000000201 1.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3WGST@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 L 1.0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage 1.0 recA 1.0 - 1.0 - 1.0 ko:K03553 1.0 ko03440,map03440 1.0 M00729 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03400 1.0 - 1.0 - 1.0 - 1.0 RecA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000201_01679 1.0 - - - - 1.0 1.0 1.0 1.0 Homologous recombination 1.0 K03553:recA; recombination protein RecA 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1538028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGTIR MGYG000002293_00342;MGYG000003697_01640 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 O 1.0 peptidylprolyl isomerase 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00342 0.5 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K01802:E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]|K03770:ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 116948 0 0 0 0 145625 0 0 0 0 0 0 237106 0 0 0 98777 304629 148170 0 0 0 322612 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179124 0 0 0 0 0 0 213191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 115238 0 0 0 0 0 240073 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1043612 0 0 0 0 1428133 0 0 0 0 0 0 2461293 0 0 0 1310701 1547604 1137930 0 0 0 2272869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105580 0 0 0 0 106960 0 0 0 0 0 0 0 0 0 0 121373 274272 818623 0 0 0 155795 0 0 0 0 0 0 0 0 0 0 +AALGTSSFMSAASFQETTK MGYG000004797_04274;MGYG000000243_01979;MGYG000002478_00805 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000004797_04274 0.3333333333333333 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 544475 0 434268 0 0 0 0 0 0 0 432093 0 0 380197 0 0 0 0 0 0 0 550381 0 0 0 0 0 0 593623 0 981904 0 0 0 0 515870 0 0 319095 0 758165 308346 0 0 0 0 612814 496068 1335066 0 0 1081136 0 0 0 483164 0 663998 0 632354 0 0 584291 0 0 0 325606 0 547610 0 0 0 0 395821 0 0 0 0 423944 0 0 0 0 0 0 0 478639 0 0 352104 0 548354 0 0 0 0 351540 0 0 0 0 448340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208303 0 479206 238793 0 0 0 0 448395 260735 971554 0 0 498134 0 665461 0 396958 0 312327 476191 371078 0 0 396811 501211 0 0 283160 0 0 0 0 0 0 338474 +AALGVLR MGYG000002494_02221 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0751@1|root,COG0751@2|Bacteria,1MV2F@1224|Proteobacteria,1RNR3@1236|Gammaproteobacteria,3XNJZ@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Glycyl-tRNA synthetase beta subunit 1.0 glyS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.14 1.0 ko:K01879 1.0 ko00970,map00970 1.0 M00360 1.0 R03654 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_2891,iE2348C_1286.E2348C_3810,iECABU_c1320.ECABU_c40010,iECED1_1282.ECED1_4242,iECH74115_1262.ECH74115_4934,iECNA114_1301.ECNA114_3710,iECOK1_1307.ECOK1_4005,iECP_1309.ECP_3661,iECS88_1305.ECS88_3976,iECSF_1327.ECSF_3393,iECSP_1301.ECSP_4554,iECs_1301.ECs4442,iG2583_1286.G2583_4300,iUMN146_1321.UM146_17960,iUTI89_1310.UTI89_C4099,ic_1306.c4378 1.0 DALR_1,tRNA_synt_2f 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02221 1.0 glycine--tRNA ligase. glycyl-tRNA synthetase. - ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01879:glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 435383 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 69841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALGVVK MGYG000002989_00405 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Marvinbryantia|s__Marvinbryantia sp900544685|m__MGYG000002989 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002989_00405 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644349 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALHEFNPMMGHR MGYG000002528_02478 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002528_02478 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 111191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 177133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 451963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 693142 0 213438 0 0 0 0 571016 0 0 613414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161892 0 0 0 0 0 0 0 173021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALHILK MGYG000002478_03659;MGYG000004797_03013 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0156@1|root,COG0156@2|Bacteria,4NJ3B@976|Bacteroidetes,2G2VS@200643|Bacteroidia,4AW5T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.3.1.47 1.0 ko:K00652 1.0 ko00780,ko01100,map00780,map01100 1.0 M00123,M00573,M00577 1.0 R03210,R10124 1.0 RC00004,RC00039,RC02725 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 AMP-binding,AMP-binding_C,Aminotran_1_2,PP-binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_03659 0.5 8-amino-7-oxononanoate synthase. AONS. The enzyme catalyzes the decarboxylative condensation of L-alanine and pimeloyl-[acyl-carrier protein], a key step in the pathway for biotin biosynthesis.-!-Pimeloyl-CoA can be used with lower efficiency. 6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]. 1.0 1.0 1.0 1.0 Biotin metabolism|Metabolic pathways 1.0 K00652:bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 896327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 664832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579170 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 911041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALIAMTK MGYG000004526_00099 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-103|s__CAG-103 sp000432375|m__MGYG000004526 1.0 COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia,36DZX@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 IQ 1.0 Enoyl-(Acyl carrier protein) reductase 1.0 baiA 1.0 - 1.0 1.1.1.100,1.1.1.159 1.0 ko:K00059,ko:K00076 1.0 ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212 1.0 M00083,M00572 1.0 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004526_00099 1.0 3-oxoacyl-[acyl-carrier-protein] reductase. | 7alpha-hydroxysteroid dehydrogenase. - Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates. | Catalyzes the oxidation of the 7alpha-hydroxy group of bile acids and alcohols both in their free and conjugated forms.-!-The Bacteroides fragilis and Clostridium enzymes can also utilize NADP(+). a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH. | cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis|Secondary bile acid biosynthesis|Prodigiosin biosynthesis|Biotin metabolism|Biosynthesis of unsaturated fatty acids|Metabolic pathways|Fatty acid metabolism 1.0 K00059:fabG, OAR1; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]|K00076:hdhA; 7-alpha-hydroxysteroid dehydrogenase [EC:1.1.1.159] 1.0 none 1.0 0 564665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1488132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALIDC(Carbamidomethyl)LA(Ala->Gly)PDR MGYG000002515_01045;MGYG000002535_02741;MGYG000002323_01572;MGYG000002494_01366;MGYG000002507_01860;MGYG000002506_00283;MGYG000000107_04278;MGYG000000235_02283;MGYG000003372_01027 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3WWJT@544|Citrobacter 0.3333333333333333 1236|Gammaproteobacteria 1.0 M 1.0 Belongs to the ompA family 0.3333333333333333 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_01045 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03286:TC.OOP; OmpA-OmpF porin, OOP family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 554478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302879 0 0 0 0 0 310717 0 0 0 0 0 0 0 786730 0 245046 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1863413 0 0 1295693 0 0 0 1475521 0 0 0 0 0 0 0 0 0 0 0 1533938 0 0 0 0 0 1515975 1475460 0 0 0 0 0 0 2267749 0 2261325 1022810 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALIDC(Carbamidomethyl)LAPDR MGYG000002515_01045;MGYG000002535_02741;MGYG000002323_01572;MGYG000002494_01366;MGYG000002507_01860;MGYG000002506_00283;MGYG000000107_04278;MGYG000000235_02283;MGYG000003372_01027 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3WWJT@544|Citrobacter 0.3333333333333333 1236|Gammaproteobacteria 1.0 M 1.0 Belongs to the ompA family 0.3333333333333333 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_01045 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03286:TC.OOP; OmpA-OmpF porin, OOP family 1.0 none 1.0 7859875 7351315 6279329 7248504 5340209 12894151 11562350 10363299 8277908 9725269 5376269 5934874 3164478 7662817 7759540 3168510 7483414 0 6741078 6920239 7223701 18778750 0 20624615 7237834 7856888 6117414 0 9008215 9254485 8760773 7644207 6244982 9526557 9939434 8287408 7098149 7045450 31709586 64908026 59883260 26634400 61316308 110195129 47321126 25239554 34379381 56782876 16196868 30503091 29182920 43128413 34224862 40714831 83989050 0 59952637 31939761 74371458 136249751 0 104124303 60535010 30154013 25092361 0 103044598 60932675 26312583 36559927 75408513 27820440 27941299 29522403 28903228 50644599 6652939 5619099 7859564 5385742 7609065 14507481 7526695 8119668 6169331 6804873 5325105 7036995 6175451 6480874 5872433 7801187 6598554 0 5740805 6674658 6262454 12691820 0 11819686 6563572 6230678 6458557 0 6496347 7142047 9623892 5463754 6696642 7668770 6687147 7859091 5359225 7463571 14457568 11430822 13293802 11628834 9268428 16695151 16791981 15479497 10696752 15168972 6791297 8173088 12061010 10717293 12684748 10037167 10894792 0 9622404 11212757 14955136 17676401 0 15033424 12778995 11632930 12319475 0 12820557 11664328 8520576 9124340 14398951 21051369 18476173 16345870 9217737 11022991 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119527 0 0 0 0 0 0 0 0 0 0 0 102558 0 +AALIDC(Carbamidomethyl)LAPDRR MGYG000002515_01045;MGYG000002535_02741;MGYG000002323_01572;MGYG000002494_01366;MGYG000002506_00283;MGYG000002507_01860;MGYG000000107_04278;MGYG000000235_02283;MGYG000003372_01027 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3WWJT@544|Citrobacter 0.3333333333333333 1236|Gammaproteobacteria 1.0 M 1.0 Belongs to the ompA family 0.3333333333333333 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_01045 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03286:TC.OOP; OmpA-OmpF porin, OOP family 1.0 none 1.0 1626790 1435181 1547851 1537585 1270162 3148465 2072372 2167282 1976511 2321243 1007094 1596752 963792 1900342 1622318 958665 1685296 0 1645396 1609172 1738887 3479321 0 4475037 1843466 1874616 1540228 0 2289065 1835101 2031936 1836098 1434835 1889330 2148796 1799974 1626111 1559831 7161022 14182719 12569340 5253027 12454199 18432767 10665365 5991222 7415784 10827862 3762179 6488491 5752885 9096479 7414129 8874206 16225264 0 12341981 6153347 14916124 25880006 0 23485532 9589467 6919194 5847710 0 18327278 10993476 5646155 7378307 14908257 6229356 6652294 6356085 6311440 10572322 1484782 1361093 1733567 1597297 2053694 3425992 1942385 1830430 1394522 1735264 1407327 1811176 1602066 1527714 1393839 1568144 1479103 0 1471645 1551509 1732049 2457974 0 3298427 1608663 1478489 1435951 0 1528992 1556504 2148945 1519618 1540045 1869683 1656194 1523706 1154571 1691432 3061910 2053644 2859085 2552895 1947182 3546220 3476755 4484973 2080539 3822873 1514142 1909039 3237113 2282938 2565982 2439508 2134551 0 2330089 2504965 3794106 4761359 0 3351626 2861774 2449764 2642314 0 2364647 2164545 1583406 1939849 3281070 4752522 4006725 3403686 2093229 2597282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59127 0 0 0 0 0 0 0 +AALIDC(Carbamidomethyl)LAPDRRVEIEVK MGYG000002515_01045;MGYG000002507_01860;MGYG000002506_00283;MGYG000003372_01027 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria,3XMXT@561|Escherichia 0.5 1236|Gammaproteobacteria 1.0 M 1.0 Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes 0.5 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_01045 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03286:TC.OOP; OmpA-OmpF porin, OOP family 1.0 none 1.0 0 0 751104 0 0 453489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459669 0 235348 0 0 0 0 0 0 582825 0 502868 0 0 0 0 636949 0 0 0 0 0 76603 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179945 0 57925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86455 0 0 279012 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216046 0 234277 0 0 0 0 0 0 261012 0 287541 94744 0 0 0 77206 0 0 289249 0 0 459766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407857 0 197030 0 0 0 0 0 0 72886 0 51973 485864 0 0 0 265236 0 0 412618 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 228561 0 193905 0 0 0 0 561324 +AALIDC(Carbamidomethyl)LGPDR MGYG000000093_01869 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Klebsiella_A|s__Klebsiella_A grimontii|m__MGYG000000093 1.0 COG2885@1|root,COG3637@1|root,COG2885@2|Bacteria,COG3637@2|Bacteria,1N6EM@1224|Proteobacteria,1RMJ7@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 M 1.0 Belongs to the ompA family 1.0 ompA 1.0 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 1.0 - 1.0 ko:K03286 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.6 1.0 - 1.0 iECIAI1_1343.ECIAI1_0998,iECNA114_1301.ECNA114_1035,iECSF_1327.ECSF_0871,iUTI89_1310.UTI89_C1022 1.0 OMP_b-brl,OmpA,OmpA_membrane,OprF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000093_01869 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03286:TC.OOP; OmpA-OmpF porin, OOP family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2371395 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALIDR MGYG000004899_03259;MGYG000001346_01624;MGYG000002549_04587 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000004899_03259 0.3333333333333333 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALIEPYAC(Carbamidomethyl)SFHC(Carbamidomethyl)IER MGYG000004735_02293 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,248Z5@186801|Clostridia,27W1F@189330|Dorea 1.0 186801|Clostridia 1.0 E 1.0 Zinc-binding dehydrogenase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_02293 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 544445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 669422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20292015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALIEPYAC(Trioxidation)SFHC(Carbamidomethyl)IER MGYG000004735_02293 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,248Z5@186801|Clostridia,27W1F@189330|Dorea 1.0 186801|Clostridia 1.0 E 1.0 Zinc-binding dehydrogenase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_02293 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1326051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALIFGNIK MGYG000004735_00330 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00330 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 780599 2295010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254658 0 0 0 0 353891 0 0 0 775389 706287 0 0 0 0 586338 +AALIFGNVKPGDAATLM(Oxidation)DYTM(Oxidation)K MGYG000001338_02427;MGYG000000184_00682 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02427 0.5 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2276021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 576984 0 0 0 0 0 0 0 +AALIFGNVKPGDAATLM(Oxidation)DYTMK MGYG000001338_02427;MGYG000000184_00682 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02427 0.5 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 0 154909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 706962 0 0 0 0 0 0 0 0 341626 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 565000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326993 0 0 0 0 0 0 0 +AALIFGNVKPGDAATLMDYTM(Oxidation)K MGYG000001338_02427;MGYG000000184_00682 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02427 0.5 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 790064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALIFGNVKPGDAATLMDYTMK MGYG000001338_02427;MGYG000000184_00682 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02427 0.5 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 0 0 0 0 1512075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8245839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALIFGNVTPGDAGTLM(Oxidation)K MGYG000000142_02504;MGYG000000050_00436;MGYG000004733_01559;MGYG000000212_01935;MGYG000000002_02256;MGYG000000201_00496;MGYG000000216_02766 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3XZDK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 acetyl-CoA decarbonylase synthase complex subunit beta 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_02504 0.14285714285714285 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 627041 809568 745084 0 0 1317009 0 947220 0 0 1141965 688296 0 656204 469510 0 1449182 0 0 1188966 641792 1110952 0 680571 858040 573785 0 0 995415 465985 1173971 0 0 0 0 0 525866 429753 242089 543267 0 0 0 410396 460548 0 0 0 0 399951 0 0 0 0 0 0 0 0 0 415077 0 682574 345126 0 0 0 667156 488009 1412169 0 346035 297907 0 0 0 344053 691507 1101931 614412 0 0 859137 576926 814437 0 0 425082 815769 0 570744 815667 629939 854280 0 796686 852199 834942 1699692 0 603642 633923 764858 0 0 874929 837282 848416 0 1014718 984615 0 0 649938 646117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALIFGNVTPGDAGTLMK MGYG000000142_02504;MGYG000000050_00436;MGYG000004733_01559;MGYG000000212_01935;MGYG000000002_02256;MGYG000000201_00496;MGYG000000216_02766 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3XZDK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 acetyl-CoA decarbonylase synthase complex subunit beta 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_02504 0.14285714285714285 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 954922 771412 1014719 422077 823758 1801615 514462 1513720 747277 1479741 1476644 1148306 1094821 591608 1049805 733865 1071712 716349 688184 987466 1377997 2006009 968361 745984 1025779 596063 919533 1278661 2474243 1397095 759304 665383 706458 661056 1032412 673626 620673 742331 1147689 768396 689598 855942 1143607 806917 1297287 1380124 773057 1025250 1262296 381075 1098603 576740 862164 460423 892052 2347925 806882 1387057 1366973 472932 863297 1497156 889706 849283 1451141 1690699 2400052 2324949 2904329 517796 1046159 1302531 1191144 1134576 1021924 997297 2531516 1263300 1453576 1188437 0 1743201 1813137 2749013 1187112 2106081 1066834 1568951 1429364 1717668 2674238 1765002 3481600 0 2578700 2632953 1744606 4377412 867813 1218983 2135149 2383450 2343093 976092 1553797 2620196 1785741 1535550 2773420 2679761 2389967 1163094 1842703 1803990 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALIHGLK MGYG000000142_02038;MGYG000000301_00188;MGYG000000171_01879;MGYG000002025_01287;MGYG000001338_02782;MGYG000004740_00893;MGYG000002286_01563;MGYG000000532_01246;MGYG000001637_00006;MGYG000003694_02453;MGYG000002052_00761;MGYG000003422_00383;MGYG000000356_00499;MGYG000001456.1_01726;MGYG000000216_02331;MGYG000002670_00411;MGYG000003695_00625;MGYG000000076_02834;MGYG000000154_01812;MGYG000000245_02664;MGYG000000136_02053;MGYG000001186_01087;MGYG000000119_00072;MGYG000000201_02106;MGYG000002492_00401;MGYG000000050_01197;MGYG000000153_02068 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.8148148148148148 rpsK 0.8148148148148148 - 1.0 - 1.0 ko:K02948 0.8148148148148148 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 0.8148148148148148 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_02038 0.037037037037037035 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 0.8148148148148148 none 1.0 2980201 5025421 2819383 1893463 4972556 4768399 1324647 2519099 1506931 1987895 4717975 2607400 4885458 2321624 2247587 4491183 3108265 5685198 1757152 4145426 3398618 4314778 2982071 1535945 2502304 1826400 1746952 3317866 2288705 2273956 1890918 4536151 3111868 3093570 2404606 1594568 2266306 3684185 2275951 7031892 3191555 1434278 2754679 1354643 1402579 1392205 1864189 965010 2205958 864268 2069496 1065558 873220 1126524 944898 3879405 1054025 1285009 0 832549 2246547 1590206 986468 1290281 1597170 3938373 2237067 1320085 6620438 2491271 3471755 2863145 2079944 2415033 1807790 3885272 3117534 7172919 9922660 3474882 3867650 3518785 2297905 3362076 2935963 3039936 4639184 2065805 5000900 2939464 3080794 6389887 4742326 3328899 2961982 2976629 3004954 4305325 3882197 2936192 3291893 2474952 3280647 4516710 3092840 3881988 4538019 7181339 9117490 3872738 3752886 2563537 3619265 8224292 1175743 4947741 1881914 1046670 0 1124555 1142968 937627 1056058 1549162 2424844 1720572 1950162 1057847 836298 2277073 1638851 1737002 922609 1586388 999398 1640083 1145046 1690681 1125480 728926 1122878 2164037 3166723 1366614 4425590 2934478 1997075 590401 822739 765354 837599 2230248 6033005 11117458 8524652 10182246 2063047 5503428 8643240 5778590 4617401 8016373 6858654 8289259 3027950 7477563 6448251 5586796 6151130 1400699 5856885 2229818 8037429 7410100 3494167 4830783 5072328 7448957 5854579 2988430 8502891 2688431 9277473 10447009 11154789 7100864 7535283 8659516 3826705 8175620 +AALIKENPLYGK MGYG000000080_03188 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes caccae|m__MGYG000000080 1.0 COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia 1.0 186801|Clostridia 1.0 P 1.0 FAD dependent oxidoreductase 1.0 glpA 1.0 - 1.0 1.1.5.3 1.0 ko:K00111 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00848 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DAO,Fer2_BFD,NAD_binding_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000080_03188 1.0 glycerol-3-phosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase. An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis.-!-In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane.-!-In eukaryotes, this enzyme, together with the cytosolic enzyme EC 1.1.1.8 forms the glycerol-3-phosphate shuttle by which NADH produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain.-!-This shuttle plays a critical role in transferring reducing equivalents from cytosolic NADH into the mitochondrial matrix.-!-Insect flight muscle uses only CoQ10 as the physiological quinone whereas hamster and rat mitochondria use mainly CoQ9.-!-The enzyme is activated by calcium.-!-Formerly EC 1.1.2.1 and EC 1.1.99.5. a quinone + sn-glycerol 3-phosphate = a quinol + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00111:glpA, glpD; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1399535 0 0 0 0 0 0 0 0 0 +AALILSK MGYG000002528_00923;MGYG000000262_01647;MGYG000000028_00102 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,26AIX@186813|unclassified Clostridiales 0.6666666666666666 186801|Clostridia 1.0 H 1.0 Pantoate-beta-alanine ligase 0.6666666666666666 panC 1.0 - 1.0 6.3.2.1 1.0 ko:K01918 1.0 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 1.0 M00119 1.0 R02473 1.0 RC00096,RC00141 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pantoate_ligase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00923 0.3333333333333333 pantoate--beta-alanine ligase (AMP-forming). pantothenate synthetase. - (R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+). 1.0 1.0 1.0 1.0 beta-Alanine metabolism|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01918:panC; pantoate--beta-alanine ligase [EC:6.3.2.1] 1.0 none 1.0 0 70263 0 0 0 361683 0 0 0 0 0 0 409003 0 0 0 0 0 0 0 0 403271 0 369598 0 0 0 0 0 0 0 573247 0 0 0 0 0 0 0 336130 0 0 0 330196 0 0 0 0 0 0 227540 0 0 0 0 0 0 0 0 247506 0 559445 0 0 0 0 0 0 0 227602 0 0 0 0 0 0 0 1733828 0 0 0 826318 0 0 0 0 0 0 725511 0 0 0 0 0 0 0 0 1548676 0 711481 0 0 0 0 0 0 0 1413167 0 0 0 0 0 0 0 431929 0 0 0 399231 0 0 0 0 0 0 303518 0 0 0 0 0 0 0 0 298767 0 310728 0 0 0 0 0 0 0 384104 0 0 0 0 0 0 0 292572 0 0 0 298269 0 0 0 0 0 0 200931 0 0 0 0 0 0 0 0 471968 0 368650 0 0 0 0 0 0 0 349909 0 0 0 0 0 0 +AALINVQR MGYG000001346_00032;MGYG000000236_00368 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0058@1|root,COG0058@2|Bacteria,4NGR1@976|Bacteroidetes,2FNN5@200643|Bacteroidia,4AP04@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG0058 Glucan phosphorylase 1.0 glgP 1.0 - 1.0 2.4.1.1,2.4.1.11,2.4.1.8 1.0 ko:K00688,ko:K00691,ko:K16153 1.0 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 1.0 - 1.0 R00292,R01555,R02111 1.0 RC00005,RC00049 1.0 ko00000,ko00001,ko01000,ko01003 1.0 - 1.0 GH65,GT3,GT35 1.0 - 1.0 DUF3417,Glycogen_syn,Phosphorylase 1.0 2.4.1.1 1.0 GT35 1.0 GT35 1.0 GT35 1.0 MGYG000001346_00032 0.5 glycogen phosphorylase. | glycogen(starch) synthase. | maltose phosphorylase. polyphosphorylase. | UDP-glucose--glycogen glucosyltransferase. This entry covers several enzymes from different sources that act in vivo on different forms of (1->4)-alpha-D-glucans.-!-Some of these enzymes catalyze the first step in the degradation of large branched glycan polymers - the phosphorolytic cleavage of alpha-1,4-glucosidic bonds from the non-reducing ends of linear poly(1->4)-alpha-D-glucosyl chains within the polymers.-!-The enzyme stops when it reaches the fourth residue away from an alpha-1,6 branching point, leaving a highly branched core known as a limit dextrin.-!-The description (accepted name) of the enzyme should be modified for each specific instance by substituting 'glycogen' with the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, etc. | The description (official name) varies according to the source of the enzyme and the nature of its synthetic product.-!-Glycogen synthase from animal tissues is a complex of a catalytic subunit and the protein glycogenin.-!-The enzyme requires glucosylated glycogenin as a primer; this is the reaction product of EC 2.4.1.186.-!-A similar enzyme utilizes ADP-glucose (cf. EC 2.4.1.21). [(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. | [(1->4)-alpha-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-alpha-D- glucosyl](n+1) + H(+) + UDP. | D-maltose + phosphate = beta-D-glucose 1-phosphate + D-glucose. 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biofilm formation - Escherichia coli|Necroptosis|Insulin signaling pathway|Glucagon signaling pathway|Insulin resistance 1.0 K00688:PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]|K00691:mapA; maltose phosphorylase [EC:2.4.1.8]|K16153:K16153; glycogen phosphorylase/synthase [EC:2.4.1.1 2.4.1.11] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 474772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALIQC(Carbamidomethyl)LDRETYNK MGYG000001365_00393 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A|s__Phascolarctobacterium_A succinatutens|m__MGYG000001365 1.0 COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,4H1ZR@909932|Negativicutes 1.0 909932|Negativicutes 1.0 E 1.0 ABC transporter substrate-binding protein family 5 1.0 dppA 1.0 - 1.0 - 1.0 ko:K02035 1.0 ko02024,map02024 1.0 M00239 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5 1.0 - 1.0 - 1.0 SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001365_00393 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 143474 0 0 0 0 0 0 0 0 0 0 0 0 0 214867 0 0 0 0 0 0 0 316628 0 196990 0 230446 0 0 0 0 0 0 0 0 0 179382 261210 364708 0 0 0 0 0 0 0 0 0 0 0 0 0 247217 0 322817 0 0 0 0 198513 251568 0 294445 0 181840 0 0 698965 0 792905 330042 411305 0 0 456629 480708 413906 0 187539 0 0 0 0 0 0 195326 0 0 0 485895 329506 0 266691 0 0 0 515715 201337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 341222 0 0 0 0 0 0 0 785245 0 1486648 1308128 1477518 0 0 938678 0 864630 1178709 762202 0 0 790722 1407684 1197254 0 790662 0 0 0 0 0 0 763263 0 0 0 895011 1909608 0 1168557 0 0 0 1045501 1574822 +AALITR MGYG000003500_01067;MGYG000001602_02150;MGYG000001464_00915;MGYG000002279_02623;MGYG000000095_03300;MGYG000002837_02841;MGYG000000255_00052;MGYG000004296_01212;MGYG000001310_00591;MGYG000000153_01249;MGYG000000164_02280;MGYG000000245_00949;MGYG000000271_00813;MGYG000004733_01566;MGYG000001300_02570;MGYG000000002_02264;MGYG000000532_02227;MGYG000000154_00209;MGYG000002517_01913;MGYG000004271_01584;MGYG000003702_00402;MGYG000001319_00319;MGYG000003381_00566;MGYG000000212_01942;MGYG000001315_00663 domain d__Bacteria 1.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia 0.32 186801|Clostridia 0.96 I 0.72 Glycerol-3-phosphate dehydrogenase 0.64 gpsA 1.0 - 1.0 1.1.1.94 1.0 ko:K00057 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00842,R00844 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 G3P_acyltransf,NAD_Gly3P_dh_C,NAD_Gly3P_dh_N 0.96 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003500_01067 0.04 glycerol-3-phosphate dehydrogenase [NAD(P)(+)]. L-glycerol-3-phosphate:NAD(P) oxidoreductase. The enzyme from Escherichia coli shows specificity for the B side of NADPH. (1) NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH. (2) NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00057:gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246385 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 897878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALITYDGK MGYG000002006_00574 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter sp900754605|m__MGYG000002006 1.0 2DX6Y@1|root,343NU@2|Bacteria,1VVG9@1239|Firmicutes,25GRP@186801|Clostridia,2N903@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location OuterMembrane, score 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002006_00574 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1184375 0 0 0 0 864951 0 0 0 0 576394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372363 0 0 0 0 502954 0 0 0 0 578450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704037 0 0 0 0 561229 0 0 0 0 439927 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 635505 0 0 0 0 1449754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1066329 0 0 0 0 1005079 0 0 0 0 705481 0 0 0 0 0 0 0 0 0 0 +AALKDQDR MGYG000001338_02425;MGYG000000301_00509;MGYG000000133_01786 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02425 0.3333333333333333 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00197:cdhE, acsC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] 1.0 none 1.0 0 131036 0 0 0 0 0 32775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16579 0 0 0 0 0 32399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 736936 0 0 0 0 0 243359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALKDQDRTFGYPSIVNLVK MGYG000001338_02425 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02425 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00197:cdhE, acsC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALKEVEALK MGYG000003899_02252;MGYG000002223_01363;MGYG000001300_01216 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3WHDD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003899_02252 0.3333333333333333 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01875:SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11] 1.0 none 1.0 597385 0 724121 549001 0 0 307773 0 0 0 0 334985 0 477874 544977 0 419202 0 758765 589594 0 640134 0 0 0 449068 484443 0 0 0 0 0 644330 637638 0 419949 469666 589656 897534 0 635239 771731 0 559309 1182007 0 0 0 0 576613 0 830212 1027494 0 1056822 0 921852 869648 0 494159 0 524113 0 915530 824163 0 0 0 0 0 688340 1204130 0 964250 838867 981742 464215 0 71072 293783 0 367576 0 0 0 0 0 67357 0 53240 566427 0 58699 0 46067 458384 0 51120 0 0 0 313208 704897 0 0 0 0 0 60217 275620 0 0 122817 156855 838689 0 868875 851101 0 907347 1070478 0 0 0 0 957616 0 925617 674907 0 842079 0 803449 860081 0 679589 0 732306 0 740353 623016 0 0 0 0 0 951548 894419 0 801854 803390 935122 0 0 125790 41764 0 46297 80992 0 0 0 0 57382 0 0 74789 0 58171 0 0 0 0 212604 0 93262 0 0 56573 0 0 0 0 0 70085 0 0 0 50759 72088 +AALKEVSGIADEK MGYG000002528_02801 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia,36G65@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 PFAM Mannitol dehydrogenase 1.0 mtlD 1.0 - 1.0 1.1.1.17 1.0 ko:K00009 1.0 ko00051,map00051 1.0 - 1.0 R02703 1.0 RC00085 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Mannitol_dh,Mannitol_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02801 1.0 mannitol-1-phosphate 5-dehydrogenase. - - D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism 1.0 K00009:mtlD; mannitol-1-phosphate 5-dehydrogenase [EC:1.1.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 720557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1920922 0 813041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 363548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 967735 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALKN(Deamidated)QDRTFGYPSIVNLVK MGYG000000031_02024 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900066205|m__MGYG000000031 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_02024 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00197:cdhE, acsC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALKNK MGYG000004221_01655;MGYG000000989_01009 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia 0.5 186801|Clostridia 1.0 K 0.5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 0.5 rpoC 0.5 - 1.0 2.7.7.6 0.5 ko:K03046 0.5 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 0.5 M00183 0.5 R00435,R00441,R00442,R00443 0.5 RC02795 0.5 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 0.5 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 0.5 - 1.0 - 1.0 - 1.0 GH1 0.5 MGYG000004221_01655 0.5 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 0.5 0.5 0.5 0.5 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 0.5 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 704498 0 886936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALKPGEALLLENLR MGYG000003697_01048 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01048 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458101 0 0 0 0 565738 0 0 0 0 690230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALKPGEALMLENLR MGYG000004464_01207 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Barnesiellaceae|g__Barnesiella|s__Barnesiella sp900542255|m__MGYG000004464 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Psort location Cytoplasmic, score 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004464_01207 1.0 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALKPGEVLLLENLR MGYG000003693_01612;MGYG000001306_01732;MGYG000002556_00160;MGYG000001783_01046;MGYG000002905_01347;MGYG000002560_01937;MGYG000004797_00163;MGYG000002478_02340 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0126@1|root,COG0126@2|Bacteria,4NFW2@976|Bacteroidetes,2FM2Q@200643|Bacteroidia,4AMS2@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 F 0.625 Psort location Cytoplasmic, score 0.5 pgk 0.625 - 1.0 2.7.2.3 0.625 ko:K00927 0.625 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.625 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.625 R01512 0.625 RC00002,RC00043 0.625 ko00000,ko00001,ko00002,ko01000,ko04147 0.625 - 1.0 - 1.0 - 1.0 PGK 0.625 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_01612 0.125 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 0.625 0.625 0.625 0.625 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.625 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 0.625 none 1.0 49036 0 0 0 0 66355 0 0 0 0 0 0 0 0 0 49994 0 0 0 0 0 0 0 0 0 0 132317 0 0 0 0 103347 0 0 0 0 0 0 0 0 0 0 56532 83987 0 173255 70073 0 125823 99810 61959 0 0 0 0 212103 118648 105896 0 0 333958 0 0 224124 75769 241650 70627 0 161314 0 56837 44351 108694 0 50193 0 1353536 589112 1574411 0 1937839 866975 1299753 862076 1374768 0 740953 1338161 1965828 0 983492 1069337 576946 1502888 1204912 1304591 869779 479463 1254609 366557 1287029 809247 1147065 1104747 1027104 1180131 915884 608255 812232 831999 1012032 0 1144097 1260059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83689 0 0 0 0 0 0 0 0 0 +AALKSALTSK MGYG000002298_00329;MGYG000001338_02806 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_00329 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALKTELGK MGYG000000271_02100 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfA 1.0 - 1.0 1.3.1.108 1.0 ko:K03522,ko:K22432 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ETF,ETF_alpha,Fer4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02100 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03522:fixB, etfA; electron transfer flavoprotein alpha subunit|K22432:carE; caffeyl-CoA reductase-Etf complex subunit CarE [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 647711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALKVSAETGK MGYG000000084_02524;MGYG000004732_02304 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000084_02524 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALLADEIAK MGYG000000077_02459;MGYG000004879_02866;MGYG000000262_01988 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,25VEG@186806|Eubacteriaceae 0.6666666666666666 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000077_02459 0.3333333333333333 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 1238274 1515919 1040615 817907 1391604 1315274 294464 1348208 417851 1299840 1084300 473291 1457891 797452 1385701 1520309 1105731 0 1088298 1405868 550540 1660217 0 367884 1461204 782193 1064426 0 243438 921893 648818 1436779 686677 964937 958751 442970 437105 800077 2422901 1744764 773087 2193799 830815 650770 3376521 1852157 2001105 1110924 559374 930070 612575 1038802 1085911 607912 752635 0 1666910 2591369 1404020 598136 0 2324165 1574657 1737693 599831 0 2938902 1029410 2038569 718255 684918 1044292 1847187 2520687 2141048 689091 5330588 5887285 1153716 8714446 913655 2981789 1782280 4763476 1827827 4266032 1421188 3489867 3140199 3597635 5553932 4125657 4500591 0 5426235 5305641 3514341 7043353 0 2010514 4791442 4498507 5634696 0 1221254 2933815 1049933 5302933 2425419 5728493 5799949 1748062 3545510 1384525 1439502 2345346 1089644 2131074 1702033 1856448 2506654 1127792 1259147 1851526 1809989 1145053 2004393 1843429 1049847 2961048 1985520 0 1120146 2145218 1155951 1801143 0 1441140 953600 666055 1397451 0 1810386 988248 1529771 1298814 1512039 174721 1278826 1180973 696177 1316108 297768 1809286 2024926 1164938 416524 1493054 1261423 1024243 509781 494335 2246881 476935 1663505 820963 624799 684807 704994 0 465154 502247 490615 2199684 0 2889988 425803 421891 460191 0 372121 434916 2512416 2068353 2593386 960163 424246 479135 358450 1400397 +AALLDR MGYG000001345_00516;MGYG000004899_03259;MGYG000002455_01538;MGYG000004876_00944;MGYG000001346_01624;MGYG000004876_03444;MGYG000002549_04587 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1185@1|root,COG1185@2|Bacteria,4NE4Q@976|Bacteroidetes,2FN5H@200643|Bacteroidia,4ANQE@815|Bacteroidaceae 0.8571428571428571 976|Bacteroidetes 1.0 J 0.8571428571428571 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 0.8571428571428571 pnp 0.8571428571428571 - 1.0 2.7.7.8 0.8571428571428571 ko:K00962 0.8571428571428571 ko00230,ko00240,ko03018,map00230,map00240,map03018 0.8571428571428571 M00394 0.8571428571428571 R00437,R00438,R00439,R00440 0.8571428571428571 RC02795 0.8571428571428571 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 0.8571428571428571 - 1.0 - 0.8571428571428571 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 - 0.8571428571428571 GH13 0.8571428571428571 MGYG000001345_00516 0.14285714285714285 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 0.8571428571428571 0.8571428571428571 0.8571428571428571 0.8571428571428571 Purine metabolism|Pyrimidine metabolism|RNA degradation 0.8571428571428571 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 0.8571428571428571 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALLEQGYDVK MGYG000001658_01343;MGYG000002098_01956 genus d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01 1.0 COG3221@1|root,COG3221@2|Bacteria,1TR0H@1239|Firmicutes,3VNPE@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 P 1.0 ABC transporter, phosphonate, periplasmic substrate-binding protein 1.0 phnD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Phosphonate-bd 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001658_01343 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 1255558 0 0 0 0 0 0 0 0 0 996512 1492958 1116205 0 0 1226058 1082814 962250 851113 0 0 0 924451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330842 0 0 0 0 0 0 0 0 0 251893 412907 0 0 0 370546 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448231 0 0 0 0 0 0 0 0 0 530400 820483 433218 0 0 0 347009 453462 454441 0 0 0 453138 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269010 0 0 0 0 0 0 0 0 0 447106 257294 0 0 0 0 577745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 981412 0 0 0 0 0 0 0 0 0 802810 1028689 0 0 0 977653 1212173 1206879 1046354 0 0 0 1087307 0 0 0 0 0 0 0 0 0 0 +AALLER MGYG000001651_00540;MGYG000003455_00764;MGYG000003266_01536;MGYG000002794_01121;MGYG000002720_01011;MGYG000003899_00855;MGYG000002926_00046;MGYG000003819_00999;MGYG000002485_00113;MGYG000004828_00425;MGYG000004893_00824;MGYG000002968_01804;MGYG000002970_01755;MGYG000002156_00127;MGYG000003074_00264;MGYG000002105_01716;MGYG000004681_00606;MGYG000001567_01289;MGYG000002978_01886;MGYG000003074_00858;MGYG000004232_00775;MGYG000001642_01723 life d__Bacteria 0.9545 COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4CUBQ@84998|Coriobacteriia 0.3181818181818182 186801|Clostridia 0.5 C 0.5 Belongs to the Glu Leu Phe Val dehydrogenases family 0.5 - 0.45454545454545453 - 0.7727272727272727 1.4.1.4 0.3181818181818182 ko:K00262 0.3181818181818182 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 0.3181818181818182 - 0.5 R00248 0.3181818181818182 RC00006,RC02799 0.5909090909090909 ko00000,ko00001,ko01000 0.36363636363636365 - 1.0 - 1.0 - 0.9545454545454546 ELFV_dehydrog,ELFV_dehydrog_N 0.5909090909090909 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001651_00540 0.045454545454545456 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.3181818181818182 0.3181818181818182 0.3181818181818182 0.3181818181818182 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 0.3181818181818182 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.3181818181818182 none 1.0 1047264 0 0 1033668 0 1491874 1207224 928447 0 963361 1259029 0 1237292 1268914 1065468 1282978 701832 2141036 2359290 0 0 1768163 2085813 1247955 0 945836 1055509 1917598 1394810 0 1266367 0 928313 0 0 0 1344751 1300993 0 0 0 0 0 0 0 0 0 0 704913 0 0 0 6939379 558738 826666 0 916593 0 0 630589 1420535 0 0 7220877 0 1748512 0 0 0 0 0 0 0 0 0 0 0 0 2791475 3976551 0 3646819 2021543 3575279 0 3140674 2617492 0 0 3553048 3880752 2971664 3951458 0 3832519 0 0 5056145 0 3348657 0 0 3931725 583073 0 0 2798873 0 3644629 0 0 0 3070673 3210675 1159298 0 1420139 463588 0 1400897 1038177 1123218 0 1581529 1341357 0 1201694 0 1249487 0 1863379 529384 1057562 0 0 1312582 537893 316525 0 688238 1300699 1730790 2132790 0 1729880 0 385562 0 0 0 955024 1609083 717191 0 0 511335 0 772072 348306 705749 0 664185 0 0 982923 574828 266298 809871 572849 439138 982390 0 0 0 0 429252 0 641004 299378 865451 1070073 0 0 0 0 0 0 0 0 421869 +AALLIQELAGGK MGYG000002438_03366 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,4NF5B@976|Bacteroidetes,2FNBF@200643|Bacteroidia,22WG1@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily 1.0 pheT 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 1.0 6.1.1.20 1.0 ko:K01890 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 B3_4,B5,FDX-ACB,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03366 1.0 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01890:FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 222342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 928771 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 594472 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALLLDTK MGYG000002385_01836;MGYG000004893_01712;MGYG000004828_01848;MGYG000002506_01063;MGYG000003372_00726;MGYG000002494_00983;MGYG000002366_02567;MGYG000002485_02553 domain d__Bacteria 1.0 COG0469@1|root,COG0469@2|Bacteria,1MU21@1224|Proteobacteria,1RMW3@1236|Gammaproteobacteria,3XMTB@561|Escherichia 0.5 1236|Gammaproteobacteria 0.625 G 0.5 Pyruvate kinase 0.875 pykF 0.625 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 0.625 2.7.1.40 1.0 ko:K00873 1.0 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050 1.0 R00200,R00430,R01138,R01858,R02320 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iECO103_1326.ECO103_1819,iPC815.YPO2393 0.625 PK,PK_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002385_01836 0.125 pyruvate kinase. phosphoenol transphosphorylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Purine metabolism|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|Glucagon signaling pathway|Type II diabetes mellitus|Human papillomavirus infection|Viral carcinogenesis|Central carbon metabolism in cancer 1.0 K00873:PK, pyk; pyruvate kinase [EC:2.7.1.40] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 171996 106106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112195 0 0 0 0 0 0 0 0 0 0 0 0 1900945 1071752 0 1118608 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189195 0 0 0 2067989 0 0 0 0 0 0 0 0 0 0 0 0 523674 684375 0 590980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431972 0 0 0 0 0 0 0 0 0 0 0 0 0 259525 0 106191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471754 0 0 0 0 0 0 0 0 0 0 0 0 270582 0 0 117671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 128206 0 0 0 253650 0 0 0 +AALLLDTKGPEIR MGYG000002385_01836;MGYG000004893_01712;MGYG000000953_00362;MGYG000004828_01848;MGYG000002506_01063;MGYG000003372_00726;MGYG000002494_00983;MGYG000002366_02567;MGYG000002485_02553 domain d__Bacteria 1.0 COG0469@1|root,COG0469@2|Bacteria,378U8@32066|Fusobacteria 0.4444444444444444 1236|Gammaproteobacteria 0.5555555555555556 G 0.5555555555555556 Pyruvate kinase 0.8888888888888888 pykF 0.5555555555555556 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 0.5555555555555556 2.7.1.40 1.0 ko:K00873 1.0 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050 1.0 R00200,R00430,R01138,R01858,R02320 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iECO103_1326.ECO103_1819,iPC815.YPO2393 0.5555555555555556 PK,PK_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002385_01836 0.1111111111111111 pyruvate kinase. phosphoenol transphosphorylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Purine metabolism|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|Glucagon signaling pathway|Type II diabetes mellitus|Human papillomavirus infection|Viral carcinogenesis|Central carbon metabolism in cancer 1.0 K00873:PK, pyk; pyruvate kinase [EC:2.7.1.40] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1175382 1533568 1575055 0 1882067 2340221 1526117 965430 0 1904795 547008 1203440 1045562 0 0 1103808 2026252 0 1349786 0 1799111 3163842 0 1738345 1618305 0 1080626 0 2203845 1839796 1080178 1076273 1709301 0 1141508 1328253 1056794 1379301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253783 104442 0 0 0 0 207835 0 0 0 0 0 0 0 0 213332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307432 278631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALLNATTVIDKAASK MGYG000003702_01296 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eisenbergiella|s__Eisenbergiella sp900066775|m__MGYG000003702 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003702_01296 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02968:RP-S20, rpsT; small subunit ribosomal protein S20 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALLPK MGYG000002494_02542 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0604@1|root,COG0604@2|Bacteria,1MWBD@1224|Proteobacteria,1RPCQ@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 C 1.0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases 1.0 qor 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003960,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016651,GO:0016655,GO:0017091,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:1901363 1.0 1.6.5.5 1.0 ko:K00344 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N,ADH_zinc_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02542 1.0 NADPH:quinone reductase. zeta-crystallin. Specific for NADPH.-!-Catalyzes the one-electron reduction of certain quinones, with the orthoquinones 1,2-naphthoquinone and 9,10-phenanthrenequinone being the best substrates.-!-Dicoumarol (cf. EC 1.6.5.2) and nitrofurantoin are competitive inhibitors with respect to the quinone substrate.-!-The semiquinone free-radical product may be non-enzymically reduced to the hydroquinone or oxidized back to quinone in the presence of O2.-!-Abundant in the lens of the eye of some mammalian species. 2 a quinone + H(+) + NADPH = 2 a 1,4-benzosemiquinone + NADP(+). 1.0 1.0 1.0 1.0 - 1.0 K00344:qor, CRYZ; NADPH:quinone reductase [EC:1.6.5.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALLTAEE(Cation_Al[III])CKSPIILGVSEGAGK MGYG000001689_03984 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia|s__Blautia coccoides|m__MGYG000001689 1.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZ5J@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 fba 1.0 - 1.0 4.1.2.13 1.0 ko:K01624 1.0 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00003,M00165,M00167,M00344,M00345 1.0 R01068,R01070,R01829,R02568 1.0 RC00438,RC00439,RC00603,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001689_03984 1.0 fructose-bisphosphate aldolase. fructose-1,6-bisphosphate triosephosphate-lyase. Also acts on (3S,4R)-ketose 1-phosphates.-!-The enzymes increase electron-attraction by the carbonyl group, some (Class I) forming a protonated imine with it, others (Class II), mainly of microbial origin, polarizing it with a metal ion, e.g. zinc.-!-Formerly EC 4.1.2.7. beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Methane metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K01624:FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALLTR MGYG000004828_01320;MGYG000002485_00846;MGYG000001300_02570 domain d__Bacteria 1.0 COG0240@1|root,COG0240@2|Bacteria,378MQ@32066|Fusobacteria 0.6666666666666666 32066|Fusobacteria 0.6666666666666666 I 1.0 Glycerol-3-phosphate dehydrogenase 1.0 gpsA 1.0 - 1.0 1.1.1.94 1.0 ko:K00057 1.0 ko00564,ko01110,map00564,map01110 1.0 - 1.0 R00842,R00844 1.0 RC00029 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 NAD_Gly3P_dh_C,NAD_Gly3P_dh_N 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004828_01320 0.3333333333333333 glycerol-3-phosphate dehydrogenase [NAD(P)(+)]. L-glycerol-3-phosphate:NAD(P) oxidoreductase. The enzyme from Escherichia coli shows specificity for the B side of NADPH. (1) NAD(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADH. (2) NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Glycerophospholipid metabolism|Biosynthesis of secondary metabolites 1.0 K00057:gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 909551 0 0 0 0 676697 0 0 0 0 0 0 0 0 808920 0 0 0 1045338 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1236815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALLVR MGYG000002293_01440 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0458@1|root,COG0458@2|Bacteria,4NEQ0@976|Bacteroidetes,2FMKD@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 EF 1.0 Carbamoyl-phosphate synthase (glutamine-hydrolyzing) 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,CPSase_sm_chain,GATase,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01440 1.0 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01955:carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 117079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 320965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 593038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALLYDEIDRNPLFR MGYG000000437_00029;MGYG000000003_02157;MGYG000001420_00882;MGYG000000074_00485;MGYG000001562_01481;MGYG000002203_01251 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG1932@1|root,COG1932@2|Bacteria,4NE06@976|Bacteroidetes,2FMET@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000437_00029 0.16666666666666666 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Vitamin B6 metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00831:serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52] 1.0 none 1.0 798194 1216675 434106 996715 549219 864136 790262 424313 793653 1148543 168296 1264242 716277 671161 942996 510231 923657 0 1017838 1117754 997424 870140 0 1038211 829431 848732 1439338 0 679633 1667820 769791 0 735703 0 756244 1189189 1168154 404372 0 1093709 0 1764645 0 0 938239 1476729 0 0 1211271 1675481 916216 0 1755889 1187071 0 0 0 1850031 0 0 0 0 1356571 1648040 1477289 0 1698620 1833659 1038817 0 0 1082612 1182549 0 1599193 0 1056683 1202807 3775967 0 1050145 401920 1030096 845152 4952574 1188637 528666 1138861 786998 1726888 849673 626077 695019 0 1021624 1006861 1682759 634650 0 1746517 2045833 3596056 1685662 0 1922367 1100586 1377804 0 2253133 2021415 1324056 3842830 2756913 3174605 3418485 0 964281 2643832 4458792 0 3430768 4394275 1891751 4102048 3138892 3209476 4856260 3033446 4648111 3264648 2459874 0 2842721 4662857 5731273 5569759 0 0 4941740 5111374 2020518 0 5042846 4630041 5862089 0 6705511 0 2107451 2045793 6056483 6337158 9052523 14195465 9447061 10246587 30405206 6867737 9276434 7699132 8935485 9784444 11556881 6881800 0 24030301 14639521 6258255 9946453 0 25062619 30397023 11605148 23494940 0 19935957 19328297 4066829 10134992 0 2045976 15269931 0 0 0 4915 46280662 21073020 31873970 12314096 +AALLYNFLDNSK MGYG000000036_00319 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Pseudoruminococcus|s__Pseudoruminococcus massiliensis|m__MGYG000000036 1.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3WGD1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine 1.0 serC 1.0 - 1.0 2.6.1.52 1.0 ko:K00831 1.0 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 1.0 M00020,M00124 1.0 R04173,R05085 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000036_00319 1.0 phosphoserine transaminase. PSAT. A pyridoxal 5'-phosphate protein.-!-This enzyme catalyzes the second step in the phosphorylated pathway of serine biosynthesis and the third step in pyridoxal 5'-phosphate biosynthesis in the bacterium Escherichia coli.-!-Pyridoxal 5'-phosphate is the cofactor for both activities and therefore seems to be involved in its own biosynthesis.-!-Non-phosphorylated forms of serine and threonine are not substrates.-!-The archaeal enzyme has a relaxed specificity and can act on L-cysteate and L-alanine as alternative substrates to O-phospho-L- serine. (1) 2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate. (2) 2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4- phosphooxybutanoate + L-glutamate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Methane metabolism|Vitamin B6 metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00831:serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 387690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 930605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1456021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196912 0 0 0 0 +AALMDPAYMQK MGYG000002438_03725 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1390@1|root,COG1390@2|Bacteria,4NP16@976|Bacteroidetes,2FMD8@200643|Bacteroidia,22Y2E@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 subunit E 1.0 - 1.0 - 1.0 - 1.0 ko:K02121 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 vATP-synt_E 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03725 1.0 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways 1.0 K02121:ATPVE, ntpE, atpE; V/A-type H+/Na+-transporting ATPase subunit E 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215632 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1707399 0 0 0 0 0 268209 0 0 3416580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802140 0 0 0 0 0 0 0 0 3973152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2583161 0 0 0 0 0 752773 0 0 4005362 0 611059 0 0 0 0 624352 0 0 0 0 0 0 0 0 0 0 +AALN(Deamidated)ANDFAK MGYG000002603_01889;MGYG000001770_00650;MGYG000001056_01056;MGYG000002293_00413 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,2FMF1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002603_01889 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463212 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 677809 0 0 0 0 867140 0 0 0 0 988640 0 0 0 0 0 0 0 0 0 432593 0 0 833540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1944164 0 0 0 0 1655933 0 0 0 0 1856712 0 0 0 0 1389172 0 0 0 0 1186705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALN(Deamidated)VSAETGHVITPHIMIPLVGEVK MGYG000001300_02837;MGYG000003921_00033 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001300_02837 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1400258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNAAK MGYG000001871_00692 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__|s__|m__MGYG000001871 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,22W14@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001871_00692 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNAGVK MGYG000002065_00792 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp002232035|m__MGYG000002065 1.0 COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria,4CV6B@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 Q 1.0 Amidohydrolase family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Amidohydro_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002065_00792 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2549085 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNAN(Deamidated)DFAK MGYG000002603_01889;MGYG000001770_00650;MGYG000001056_01056;MGYG000002293_00413 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,2FMF1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002603_01889 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 280533 0 0 0 0 0 0 0 0 0 266819 0 0 0 0 452298 0 0 0 382955 643375 220511 0 0 0 296063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797550 0 0 0 0 0 493070 0 0 0 364543 0 0 0 0 0 0 0 0 0 0 0 0 454440 0 0 359784 0 0 0 0 0 0 409760 0 0 0 0 0 0 0 0 199927 0 557195 0 0 0 424005 0 0 0 0 269851 0 0 0 0 268276 0 0 1876336 0 0 2312751 0 0 0 0 0 0 1402708 0 0 0 0 3434131 0 0 0 0 4920429 460596 0 0 0 2959031 0 0 0 0 2436371 1459540 0 0 0 2240422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNANDFAK MGYG000002603_01889;MGYG000001770_00650;MGYG000001056_01056;MGYG000002293_00413 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,2FMF1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002603_01889 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 289933 0 278912 515517 402983 376820 501688 470891 0 326222 712914 390303 308655 252326 0 387358 218709 248815 0 0 0 373215 426918 522630 201290 441484 0 166849 0 0 416896 517395 443117 413382 329928 0 547604 360362 0 0 0 677611 0 0 458567 596742 0 0 204371 565897 0 125307 0 284827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326577 0 452994 533190 666052 655214 568231 520159 0 0 605447 535035 579834 560485 0 278953 514902 778634 0 0 0 449659 348605 528791 745322 0 0 630557 0 0 538735 382708 0 449908 441727 0 647982 308743 0 0 26941534 8591188 15088863 25010938 9407547 12224190 0 8926293 25008433 10648029 16453635 8939563 0 12837544 8609195 58717931 0 0 0 29221717 60130450 31105626 11162134 9928046 0 40948399 0 0 11743631 9998129 28387816 12270371 10955731 0 10342197 26499244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNANDFAKAE MGYG000002293_00413 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0811@1|root,COG0811@2|Bacteria,4NE8M@976|Bacteroidetes,2FMF1@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family protein 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00413 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 425786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2046800 0 0 0 0 0 0 0 0 0 0 0 5343041 0 0 0 1916729 5670802 2291778 0 0 0 7054895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1428049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNATDAMEALK MGYG000002517_00130 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1551@1|root,COG1551@2|Bacteria,1VEEF@1239|Firmicutes,24QPD@186801|Clostridia 1.0 186801|Clostridia 1.0 T 1.0 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding 1.0 csrA 1.0 - 1.0 - 1.0 ko:K03563 1.0 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019 1.0 - 1.0 - 1.0 - 1.0 CsrA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00130 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Biofilm formation - Pseudomonas aeruginosa|Biofilm formation - Escherichia coli|Biofilm formation - Vibrio cholerae 1.0 K03563:csrA; carbon storage regulator 1.0 none 1.0 670853 0 0 796838 0 0 0 870789 498357 673131 0 0 0 712899 637593 0 0 0 788772 0 0 0 0 0 0 818820 677776 0 0 587121 0 0 0 0 562123 867692 0 0 402827 0 0 377074 0 0 0 460553 499731 270382 0 0 0 249582 203658 0 0 0 357020 0 0 0 0 0 0 357113 415403 0 0 335901 0 0 0 0 317922 464674 408660 0 272658 0 0 0 0 0 0 151217 371701 388803 0 0 0 484172 398645 0 0 0 672428 0 0 0 0 0 0 338512 365520 0 0 301648 0 0 0 0 359444 115432 294523 0 1228901 0 0 1041126 0 0 0 1436337 1356234 681335 0 0 0 1214932 1275646 0 0 0 841807 0 0 0 0 0 0 1598654 1193086 0 0 816010 0 0 0 0 1410493 1305577 2006833 0 1860386 0 0 452608 0 0 0 1825455 2129987 2102362 0 0 0 1682745 2301250 0 0 0 0 0 0 0 0 0 0 1862978 1868157 0 0 2405468 0 0 0 0 2002370 1972845 2385308 0 +AALNDDMMFRPL MGYG000001338_00105;MGYG000000184_02260 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3XYP0@572511|Blautia 1.0 186801|Clostridia 1.0 G 1.0 Galactose mutarotase-like 1.0 - 1.0 - 1.0 3.2.1.20 1.0 ko:K01187 1.0 ko00052,ko00500,ko01100,map00052,map00500,map01100 1.0 - 1.0 R00028,R00801,R00802,R06087,R06088 1.0 RC00028,RC00049,RC00077 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH31 1.0 - 1.0 DUF5110,Gal_mutarotas_2,Glyco_hydro_31 1.0 3.2.1.20 1.0 GH31 1.0 GH31 1.0 GH31 1.0 MGYG000001338_00105 0.5 alpha-glucosidase. maltase-glucoamylase. Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.-!-The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links. Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. 1.0 1.0 1.0 1.0 Galactose metabolism|Starch and sucrose metabolism|Metabolic pathways 1.0 K01187:malZ; alpha-glucosidase [EC:3.2.1.20] 1.0 none 1.0 0 218186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1132731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNKK MGYG000001310_02091;MGYG000001374_01835;MGYG000000249_01353 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3XYK6@572511|Blautia 0.6666666666666666 186801|Clostridia 1.0 F 0.6666666666666666 Psort location Cytoplasmic, score 0.6666666666666666 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_02091 0.3333333333333333 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 829459 0 0 0 0 0 0 0 0 0 0 0 0 0 579137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 540028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 872577 0 0 0 0 1130399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723405 0 0 0 0 0 0 0 0 0 0 0 0 0 888039 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1047348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNLK MGYG000001346_03130;MGYG000000196_03455;MGYG000004748_02411 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG4658@1|root,COG4658@2|Bacteria,4NFGW@976|Bacteroidetes,2FMD0@200643|Bacteroidia,4AN66@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol 1.0 nqrB 0.6666666666666666 - 1.0 1.6.5.8 1.0 ko:K00347 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 NQR2_RnfD_RnfE 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_03130 0.3333333333333333 NADH:ubiquinone reductase (Na(+)-transporting). Na(+)-translocating NADH-quinone reductase. An iron-sulfur flavoprotein, containing two covalently bound molecules of FMN, one non-covalently bound FAD, one riboflavin, and one [2Fe-2S] cluster.-!-Formerly EC 1.6.5.8. a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+). 1.0 1.0 1.0 1.0 - 1.0 K00347:nqrB; Na+-transporting NADH:ubiquinone oxidoreductase subunit B [EC:7.2.1.1] 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4306765 0 0 0 0 0 0 1001108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12750909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNLMGK MGYG000000205_00558;MGYG000001338_01153 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,21XG4@1506553|Lachnoclostridium 0.5 186801|Clostridia 1.0 E 0.5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) 1.0 dapA 1.0 - 1.0 4.3.3.7 1.0 ko:K01714 1.0 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 1.0 M00016,M00525,M00526,M00527 1.0 R10147 1.0 RC03062,RC03063 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHDPS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_00558 0.5 4-hydroxy-tetrahydrodipicolinate synthase. dihydrodipicolinate synthetase. The reaction can be divided into three consecutive steps: Schiff base formation with pyruvate, the addition of L-aspartate-semialdehyde, and finally transimination leading to cyclization with simultaneous dissociation of the product.-!-The product of the enzyme was initially thought to be (S)-2,3- dihydrodipicolinate, and the enzyme was classified accordingly as EC 4.2.1.52.-!-Later studies of the enzyme from the bacterium Escherichia coli have suggested that the actual product of the enzyme is (2S,4S)-4-hydroxy- 2,3,4,5-tetrahydrodipicolinate, and thus the enzyme has been reclassified as 4-hydroxy-tetrahydrodipicolinate synthase.-!-However, the identity of the product is still controversial, as more recently it has been suggested that it may be (S)-2,3- dihydrodipicolinate after all.-!-Formerly EC 4.2.1.52. L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5- tetrahydrodipicolinate + H(+) + H2O. 1.0 1.0 1.0 1.0 Monobactam biosynthesis|Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01714:dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2318032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2297650 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNLVDNATTPLPR MGYG000001378_02876 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG4085@1|root,COG4085@2|Bacteria,4PN55@976|Bacteroidetes,2G0QX@200643|Bacteroidia,4AQT0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 Fimbrillin-like 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BACON,Mfa_like_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_02876 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1087059 0 0 0 0 913169 1340246 0 1288975 0 2690514 999137 0 0 937185 0 0 0 0 0 885066 634234 0 1274537 0 1038047 1130192 0 0 0 0 0 0 0 0 1525023 1022476 0 0 0 0 0 0 0 94849 0 57128 0 406838 0 0 0 74122 0 0 0 0 0 0 109439 0 0 0 0 75879 0 0 0 0 0 0 0 0 0 69096 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63108 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1060380 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147421 610723 0 612570 0 0 0 0 0 0 0 0 0 0 0 0 262717 0 +AALNNEVTNVLKEK MGYG000001400_03182 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Erysipelatoclostridium|s__Erysipelatoclostridium ramosum|m__MGYG000001400 1.0 COG1196@1|root,COG3525@1|root,COG1196@2|Bacteria,COG3525@2|Bacteria,1TQPP@1239|Firmicutes,25BQV@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Glycosyl hydrolase family 20, catalytic domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 F5_F8_type_C,FIVAR,Glyco_hydro_20,Glyco_hydro_20b,MucBP 1.0 - 1.0 GH20 1.0 GH20 1.0 GH20 1.0 MGYG000001400_03182 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 4518831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNSQQGEPWQTIR MGYG000002494_01052 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1482@1|root,COG1482@2|Bacteria,1MUD8@1224|Proteobacteria,1RQX8@1236|Gammaproteobacteria,3ZISM@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Phosphomannose isomerase type I 1.0 manA 1.0 GO:0000032,GO:0000271,GO:0003674,GO:0003824,GO:0004476,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006013,GO:0006056,GO:0006057,GO:0006139,GO:0006464,GO:0006486,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009242,GO:0009298,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019309,GO:0019318,GO:0019320,GO:0019438,GO:0019538,GO:0019673,GO:0031506,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0042546,GO:0043170,GO:0043412,GO:0043413,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046377,GO:0046483,GO:0055086,GO:0070085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 5.3.1.8 1.0 ko:K01809 1.0 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 1.0 M00114 1.0 R01819 1.0 RC00376 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_696,iECOK1_1307.ECOK1_1731,iECS88_1305.ECS88_1659,iSFV_1184.SFV_1629,iSF_1195.SF1636,iSFxv_1172.SFxv_1833,iS_1188.S1767,iUMN146_1321.UM146_09090,iUTI89_1310.UTI89_C1801 1.0 PMI_typeI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01052 1.0 mannose-6-phosphate isomerase. phosphomannose isomerase. - D-mannose 6-phosphate = D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01809:manA, MPI; mannose-6-phosphate isomerase [EC:5.3.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 565750 0 0 1028711 0 0 0 0 0 0 0 0 0 0 0 0 988887 0 0 1412296 0 866186 797809 0 0 0 930268 0 0 0 706680 0 0 0 0 511556 0 0 696580 0 0 495274 0 0 0 0 0 0 0 0 0 0 0 0 312379 0 0 0 0 320574 589651 0 0 0 373442 0 0 0 0 0 0 0 0 486539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 273093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNVK MGYG000000142_02834;MGYG000000463_01481;MGYG000000140_01464;MGYG000000417_00539;MGYG000003547_00119;MGYG000001698_00702;MGYG000000249_01089;MGYG000001315_01921;MGYG000001871_00692;MGYG000002963_02777;MGYG000000242_00224;MGYG000004296_00104;MGYG000002945_01502;MGYG000000133_02955;MGYG000002596_00549;MGYG000000201_02673;MGYG000002279_01986;MGYG000000251_01169;MGYG000004558_03187;MGYG000000383_01314;MGYG000003697_00176;MGYG000000164_00358;MGYG000000404_01435;MGYG000002966_02744;MGYG000002293_00650;MGYG000000187_00493;MGYG000002492_01692;MGYG000000806_02014;MGYG000000089_02490;MGYG000000243_00081;MGYG000003219_00291;MGYG000000002_01928;MGYG000001310_01399 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.2727272727272727 186801|Clostridia 0.8787878787878788 G 0.9090909090909091 Belongs to the PEP-utilizing enzyme family 0.6363636363636364 ppdK 0.9090909090909091 - 1.0 2.7.9.1 0.9090909090909091 ko:K01006 0.9090909090909091 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.9090909090909091 M00169,M00171,M00172,M00173 0.9090909090909091 R00206 0.9090909090909091 RC00002,RC00015 0.9090909090909091 ko00000,ko00001,ko00002,ko01000 0.9090909090909091 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9090909090909091 - 1.0 - 1.0 - 1.0 GT1 0.9090909090909091 MGYG000000142_02834 0.030303030303030304 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.9090909090909091 0.9090909090909091 0.9090909090909091 0.9090909090909091 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 0.9090909090909091 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 0.9090909090909091 none 1.0 0 0 0 0 4395827 0 0 0 0 0 0 4287787 0 0 0 0 0 0 0 414734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2216072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4320730 0 0 0 0 3947903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9094760 4047464 0 0 0 0 0 0 0 0 0 6631438 0 0 0 0 0 5061095 0 0 2063235 1282346 0 0 1039716 0 0 0 0 0 0 913793 0 0 1208036 0 0 0 0 0 0 0 0 0 0 0 1734458 838691 0 0 0 723570 0 1885019 0 0 0 0 0 5657071 0 0 0 0 0 3455804 0 0 0 0 10400419 0 0 5795997 0 0 0 0 0 0 0 0 0 0 0 0 0 4402518 0 0 0 0 0 0 0 +AALNVQAK MGYG000001356_00630;MGYG000002727_00240 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.5 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001356_00630 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 559293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNVQK MGYG000002035_01821;MGYG000002099_01951;MGYG000001687_00537;MGYG000000271_00388;MGYG000004735_00207;MGYG000004487_00114;MGYG000000245_03386;MGYG000001688_03814;MGYG000000258_01879;MGYG000001619_00896;MGYG000002926_01683;MGYG000002143_00035;MGYG000002707_01357;MGYG000003979_01382;MGYG000003074_00103;MGYG000004271_01396;MGYG000000152_05136;MGYG000003504_01005;MGYG000000099_03199;MGYG000002517_01243;MGYG000002025_01833;MGYG000002845_01363;MGYG000004475_00310;MGYG000002720_01364;MGYG000000131_01163;MGYG000003013_00135;MGYG000002794_01254;MGYG000000268_00698;MGYG000001496_03326;MGYG000001733_00637;MGYG000000076_02377;MGYG000003628_00298;MGYG000001607_01964;MGYG000000387_01345;MGYG000001439_01567 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.37142857142857144 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.8285714285714286 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 0.9714285714285714 MGYG000002035_01821 0.02857142857142857 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 2889189 2449255 8433559 4076321 2752624 0 0 0 0 0 0 4979941 6411642 8532124 3834748 3865164 0 6466400 6339059 0 0 0 0 9262495 0 0 4291037 0 7746102 0 0 2483149 0 0 0 0 0 0 0 252515 0 0 498279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2548864 0 0 0 0 0 0 0 0 0 0 0 2584337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4790627 0 8477072 6119867 0 0 0 9646218 0 0 0 0 0 0 0 0 0 8194178 0 0 0 0 0 0 0 7849092 0 0 18117579 0 0 0 0 0 0 0 0 10593652 0 13526726 0 0 4697162 0 0 20086994 0 0 0 0 0 0 0 0 0 26880874 0 0 0 0 11922321 15119520 5893735 17294558 0 0 14743022 15168050 0 14595042 14802306 0 36180806 29569563 15591715 0 4211982 15045923 18875001 12405861 0 9315907 17725309 0 29800835 0 6152148 0 10692897 10483270 3939086 17631752 25201924 0 46462220 0 22605665 +AALNVQKK MGYG000002720_01364;MGYG000000131_01163;MGYG000000271_00388;MGYG000002794_01254;MGYG000004487_00114;MGYG000000245_03386;MGYG000001733_00637 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.7142857142857143 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 0.8571428571428571 MGYG000002720_01364 0.14285714285714285 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 306572 0 1107483 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNVSAETGC(Carbamidomethyl)MITPH MGYG000000022_02788 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000022_02788 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1192127 0 0 0 0 1079589 0 0 0 0 1135880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 772007 0 0 0 0 1110784 0 0 0 0 948882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1582674 0 0 0 0 2272961 0 0 0 0 2149208 0 0 0 0 0 0 0 0 0 0 +AALNVSAETGHVITPH MGYG000001300_02837;MGYG000003921_00033 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001300_02837 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 2017927 2071405 2507129 2225214 648301 1852408 1408423 944430 1638011 0 1599224 1246798 2248453 1759252 2282723 2286621 2364378 2761071 2642005 2299060 925717 2158406 2370240 1537233 2510016 2141003 2558314 2275653 664407 1111788 1621789 1225965 2170107 2184159 944054 1928117 1518874 1988352 7422716 4169482 5607486 6221557 3409377 5036856 8616943 2702646 8390909 1458637 3437226 5562069 3454904 8032832 5964075 4114197 7274533 2618713 8448025 8745649 2891815 3437379 2436866 4803966 8585713 8727405 6747915 2308217 1340581 5031467 5693537 3252152 5116339 5988745 2418663 6922538 6723868 4906426 1088968 515331 745270 1491836 655025 544468 1121480 414127 1068447 381945 1209753 1127304 797349 1413927 1228760 932357 440632 876765 757718 1094632 720183 505365 1226283 927485 1042609 1107659 688623 1191564 553434 760783 698948 539660 685060 1209707 116076 1205254 1054998 623148 3764053 5900611 8322200 4909315 7184434 6647891 7218602 2157903 5495616 4718966 5371485 5542543 6102437 5542260 3974795 5975095 5968346 3572784 6194193 5334426 4314004 6982492 2880224 6492153 3683206 3056746 4728992 4700960 2724284 5358075 9373188 5910612 9252169 3457070 1420868 4034515 4467747 9266004 0 116758 0 197696 490032 128091 0 91922 175985 148831 206029 476411 237929 0 0 185496 113069 666785 0 121258 135137 263642 810468 255133 96761 0 0 868976 204003 284650 104053 582709 0 0 170872 0 0 0 +AALNVSAETGHVITPHIM(Oxidation)IPLVGEVK MGYG000001300_02837;MGYG000003921_00033 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001300_02837 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 296979 0 492352 0 0 304362 111737 0 257977 0 243169 261865 0 255204 265372 0 407047 0 0 355487 164467 364498 0 190818 0 234337 0 0 0 0 242050 0 337049 273050 0 249916 169353 324784 382097 0 356473 0 0 397278 594082 0 754841 0 356190 408892 0 582261 505392 0 459149 0 0 494239 202751 277262 0 319018 0 427254 0 0 0 0 522364 0 380643 537449 0 453924 500681 484465 211386 0 0 0 0 0 0 0 0 0 119797 305083 0 0 203069 0 0 0 0 0 88362 0 0 0 0 0 0 0 0 0 90369 0 0 0 0 105694 176462 0 85108 0 499710 0 0 110640 107442 0 96794 0 136939 462023 0 259805 189952 0 86444 0 0 249520 2652108 40960 0 0 0 132161 0 0 0 0 97595 0 555966 1376300 0 51294 841804 307197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALNVSAETGHVITPHIMIPLVGEVK MGYG000001300_02837;MGYG000003921_00033 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001300_02837 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 9376998 7937471 137078 0 6689289 0 0 0 4155191 4185865 0 8222564 0 0 0 0 0 0 0 0 8387322 0 5493127 0 0 0 0 0 0 0 0 8858740 0 0 5732497 0 14159067 0 16799933 5517436 7443380 0 12726868 0 0 0 0 11934100 0 6788026 0 0 0 0 0 0 0 0 0 0 17864148 0 0 0 0 0 0 0 0 7756918 0 0 10682207 0 5969942 0 0 0 0 0 0 0 0 0 1751709 0 0 0 0 0 0 0 0 0 0 0 0 0 3006004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2121634 9384680 0 0 1777473 0 0 0 4526371 3425643 0 11347508 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3237008 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALPADVNAPK MGYG000002395_01221;MGYG000003452_01305;MGYG000003683_00172;MGYG000001490_01230 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4D0QF@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit 1.0 rplT 1.0 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 1.0 - 1.0 ko:K02887 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 E3_binding,Ribosomal_L20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002395_01221 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02887:RP-L20, MRPL20, rplT; large subunit ribosomal protein L20 1.0 none 1.0 621621 745431 1350682 0 0 579568 0 600394 0 0 673054 0 0 0 715591 1922715 484636 0 0 931271 0 453168 0 578667 0 498534 387393 0 522815 0 328651 383801 955984 0 0 365597 472630 1405829 1484166 1419867 3038459 0 0 3665010 0 1525030 0 0 1722784 0 7246278 0 0 2014446 873756 0 0 1637586 0 2219882 0 7082882 0 1194454 1680587 0 2212589 0 3238309 1003272 2534540 0 0 2031336 1490723 3867049 1689495 1863439 1363587 0 0 0 0 0 0 0 0 0 1387262 0 2131464 2963921 1731323 0 0 2230808 0 635522 0 0 0 1067159 2026525 0 1216655 0 0 1385445 3363016 0 0 0 0 877663 0 629910 0 0 0 0 0 0 0 0 1454517 0 0 0 0 2044039 616362 0 0 0 0 3009271 0 3117661 0 0 0 0 1118777 0 792884 0 0 0 0 0 0 620967 0 0 0 0 0 0 0 0 0 0 639005 0 680728 0 0 228475 0 0 0 0 0 0 0 0 0 462724 0 0 0 0 0 0 0 0 0 0 430174 0 +AALPADVNAPKEA MGYG000003683_00172 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4D0QF@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 J 1.0 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit 1.0 rplT 1.0 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016020,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0071944,GO:1990904 1.0 - 1.0 ko:K02887 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 E3_binding,Ribosomal_L20 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00172 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02887:RP-L20, MRPL20, rplT; large subunit ribosomal protein L20 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALPAIFNPEDLNALEQALR MGYG000002960_00221;MGYG000002438_02893;MGYG000003697_02506;MGYG000000098_00813;MGYG000000196_04138;MGYG000001056_01453;MGYG000002293_02658;MGYG000001337_03724;MGYG000000243_00603;MGYG000004629_01151;MGYG000004885_01160 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG2086@1|root,COG2086@2|Bacteria,4NFWB@976|Bacteroidetes,2FMG3@200643|Bacteroidia 0.45454545454545453 976|Bacteroidetes 1.0 C 1.0 Electron transfer flavoprotein 0.5454545454545454 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002960_00221 0.09090909090909091 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 18845745 0 422202 0 152279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 510040 0 0 0 0 0 22266078 1695231 15473522 5815058 0 21732754 568455 2424947 85357 0 0 0 0 20941279 91771 0 0 0 0 0 0 60074 0 0 0 0 14479172 0 0 0 247365 10341879 277338 0 0 0 0 0 0 78127 12668588 15543202 0 20806966 161047 18516562 16727005 0 0 0 0 17525922 7529249 0 0 0 0 0 0 2201821 0 0 0 0 16283701 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4704549 9822892 4484428 0 0 0 0 4340679 0 0 0 0 0 0 21142559 0 0 0 0 25387761 0 0 0 3066837 22576398 12128644 0 0 0 16668242 0 0 16548172 9463686 15933014 0 6621923 13104261 735686 19369064 20002988 0 0 0 19643618 5669478 0 0 0 0 0 0 0 0 0 0 0 23889807 0 0 0 21688662 0 8685933 0 10765910 0 0 0 8742909 14164778 26079479 15462037 0 7307783 27398507 0 23065506 +AALPEAKPVLMEPIGELK MGYG000002794_00741;MGYG000002926_00766;MGYG000001824_01321;MGYG000002720_00009;MGYG000004525_01177 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes 1.0 1239|Firmicutes 1.0 J 1.0 elongation factor G 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002794_00741 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 978893 0 767705 1193092 0 0 0 0 0 0 0 0 0 0 0 0 690327 0 549232 0 823735 0 0 0 0 896739 0 0 0 0 0 0 945032 0 0 0 0 0 0 0 0 200969 0 0 0 0 0 0 0 0 0 0 0 0 211214 0 0 0 0 0 0 0 0 164718 0 0 0 0 0 0 98443 0 0 0 0 0 595443 0 401804 691084 0 0 0 0 0 0 0 0 0 0 0 0 641432 0 563064 0 545754 0 0 0 0 640182 0 0 0 0 0 0 521607 0 0 0 0 0 187006 0 280705 339246 0 0 0 0 0 0 0 0 0 0 0 0 142952 0 330646 0 391808 0 0 0 0 228161 0 0 0 0 0 0 165230 0 0 0 0 0 0 0 109088 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALPEQVQIWK MGYG000002494_03187 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0134@1|root,COG0135@1|root,COG0134@2|Bacteria,COG0135@2|Bacteria,1MW5K@1224|Proteobacteria,1RNYH@1236|Gammaproteobacteria,3WWTA@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Indole-3-glycerol phosphate synthase 1.0 trpC 1.0 GO:0000162,GO:0003674,GO:0003824,GO:0004425,GO:0004640,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 4.1.1.48,5.3.1.24 1.0 ko:K13498 1.0 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 1.0 M00023 1.0 R03508,R03509 1.0 RC00944,RC00945 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iPC815.YPO2205,iSBO_1134.SBO_1804,iSDY_1059.SDY_1330 1.0 IGPS,PRAI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03187 1.0 indole-3-glycerol-phosphate synthase. | phosphoribosylanthranilate isomerase. indoleglycerol phosphate synthetase. | PRAI. In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.3.27, EC 4.2.1.20 and EC 5.3.1.24). | In some organisms, this enzyme is part of a multifunctional protein together with one or more components of the system for biosynthesis of tryptophan (EC 2.4.2.18, EC 4.1.1.48, EC 4.1.3.27 and EC 4.2.1.20). 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)- 1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O. | N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1- deoxy-D-ribulose 5-phosphate. 1.0 1.0 1.0 1.0 Phenylalanine, tyrosine and tryptophan biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K13498:trpCF; indole-3-glycerol phosphate synthase / phosphoribosylanthranilate isomerase [EC:4.1.1.48 5.3.1.24] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 864311 0 0 1795031 0 0 0 0 0 854431 0 0 0 0 1132054 0 0 0 0 2623069 0 1556264 1240558 0 0 0 0 0 0 0 879587 0 0 0 0 678070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALPHGLK MGYG000001315_01363 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,25QPE@186804|Peptostreptococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfE 1.0 - 1.0 - 1.0 ko:K03613 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS05585 1.0 FMN_bind,Rnf-Nqr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01363 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03613:rnfE; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit E 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALPIGEALPASPGAAAGK MGYG000002528_02478 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002528_02478 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 276684 0 0 0 0 0 0 0 0 0 0 0 552295 0 0 0 239685 234197 0 0 0 0 421481 0 0 0 0 0 0 0 0 0 0 0 476410 0 0 0 292941 0 0 0 0 0 0 0 0 0 0 0 2062355 0 0 0 0 1147105 639581 0 0 0 1685860 0 0 0 311610 0 0 0 0 0 0 0 2474826 429441 0 0 1309242 0 0 0 726240 0 824120 0 569846 598604 0 759108 443620 1419028 0 0 3647241 1088998 816895 0 0 682160 1427539 2582637 0 0 2398072 876120 652643 0 0 0 568051 0 1244127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 770671 0 0 0 0 0 168045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217433 0 0 0 0 331166 0 0 0 0 0 0 0 0 0 0 +AALPLHHLVEK MGYG000002494_03189 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0159@1|root,COG0159@2|Bacteria,1MXJV@1224|Proteobacteria,1RMGN@1236|Gammaproteobacteria,3WWIJ@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 E 1.0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate 1.0 trpA 1.0 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 4.2.1.20 1.0 ko:K01695 1.0 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 1.0 M00023 1.0 R00674,R02340,R02722 1.0 RC00209,RC00210,RC00700,RC00701,RC02868 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECED1_1282.ECED1_1467,iECP_1309.ECP_1308 1.0 Trp_syntA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03189 1.0 tryptophan synthase. tryptophan synthetase. The alpha-subunit catalyzes the conversion of 1-C-(indol-3- yl)glycerol 3-phosphate to indole and D-glyceraldehyde 3-phosphate (this reaction was listed formerly as EC 4.1.2.8).-!-The indole migrates to the beta-subunit where, in the presence of pyridoxal 5'-phosphate, it is combined with L-serine to form L-tryptophan.-!-In some organisms this enzyme is part of a multifunctional protein that also includes one or more of the enzymes EC 2.4.2.18, EC 4.1.1.48, EC 4.1.3.27 and EC 5.3.1.24.-!-In thermophilic organisms, where the high temperature enhances diffusion and causes the loss of indole, a protein similar to the beta subunit can be found (EC 4.2.1.122).-!-That enzyme cannot combine with the alpha unit of EC 4.2.1.20 to form a complex. (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K01695:trpA; tryptophan synthase alpha chain [EC:4.2.1.20] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1046273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1620562 0 1012820 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 139593 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALPTINYLVEHNAR MGYG000002557_00596;MGYG000001709_02050;MGYG000001718_00620;MGYG000002050_01271;MGYG000000188_00828;MGYG000003073_01053;MGYG000004746_01527;MGYG000001636_00874;MGYG000003274_01602;MGYG000003851_00622;MGYG000004681_01192;MGYG000002919_00267;MGYG000000333_00451;MGYG000002775_01123;MGYG000002970_00370;MGYG000000802_01544 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,4CUGT@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 F 1.0 Belongs to the phosphoglycerate kinase family 1.0 pgk 1.0 - 1.0 2.7.2.3 1.0 ko:K00927 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01512 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002557_00596 0.0625 phosphoglycerate kinase. - - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3] 1.0 none 1.0 969119 2209372 893285 395441 555670 540865 234803 730275 494060 651576 939173 652033 1477151 0 486588 1431139 490329 581067 501583 529807 296238 845271 573209 306232 0 478826 546995 826444 826325 712782 827336 0 752874 0 360092 768258 471471 467580 467591 659576 266872 506860 584931 213625 670870 753433 423664 480976 913325 471293 918154 0 353415 563026 274088 1628397 350018 625067 261879 236647 741890 614505 0 505501 761217 1461777 641316 626704 0 0 183752 0 499424 508593 384042 299405 627914 704810 298743 522435 200181 324595 391280 613366 257785 525694 332559 492705 749976 0 617124 1027790 1103409 256627 580144 660735 564413 691161 536811 219717 0 495385 696199 561242 730015 690730 285084 0 567343 0 742650 330214 483895 365453 391132 167839 144165 293200 464954 231482 244857 244449 236611 273111 597927 222134 1181349 0 213363 975591 328299 93634 219500 237439 297084 357759 0 247572 0 131149 337761 0 299732 537143 120918 0 164938 0 160415 150117 243456 151725 219268 260458 197416 339071 204598 119638 450788 281508 176625 357974 523748 330961 440801 0 296043 573302 193111 172646 129668 158912 391759 175804 340685 209032 0 160798 458814 475230 154238 132834 405954 0 517911 0 62246 196374 143562 124187 +AALPTIQK MGYG000001300_02037;MGYG000000245_03070;MGYG000002274_01739;MGYG000002517_01027;MGYG000000022_00457;MGYG000000255_01167;MGYG000000909_00645;MGYG000000489_00504;MGYG000002040_00807;MGYG000000193_03246 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia 0.6 186801|Clostridia 1.0 F 0.6 Belongs to the phosphoglycerate kinase family 0.6 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 1.0 ko:K00927,ko:K01803 1.0 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 1.0 RC00002,RC00043,RC00423 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02037 0.1 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 1.0 none 1.0 0 0 654904 0 0 0 0 0 327639 0 0 0 0 0 0 0 0 0 932554 0 0 0 0 0 0 0 0 0 0 0 0 0 310878 620691 0 0 0 198404 0 0 234229 0 0 0 0 0 239021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204749 243204 0 0 0 207804 0 0 837376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 523337 0 0 0 0 0 0 0 0 0 0 0 0 0 759711 659495 0 0 0 630707 0 0 1378834 0 0 0 0 0 2477575 0 0 0 0 0 0 0 0 0 2264351 0 0 0 0 0 0 0 0 0 0 0 0 0 1606831 1975625 0 0 0 1434928 0 0 985489 0 0 0 0 0 870861 0 0 0 0 0 0 0 0 0 1131999 0 0 0 0 0 0 0 0 0 0 0 0 0 947465 1278571 0 0 0 865266 +AALPTLK MGYG000003694_01736;MGYG000000038_02186;MGYG000003922_03393;MGYG000000365_01000;MGYG000000138_00869;MGYG000000045_02628;MGYG000003701_03777;MGYG000004552_00730;MGYG000000415_01539;MGYG000000262_01196;MGYG000003628_01098;MGYG000000119_00719;MGYG000001490_00976;MGYG000003828_01579;MGYG000001687_00180;MGYG000002360_00441;MGYG000004727_00660;MGYG000001797_01330;MGYG000003684_03801;MGYG000001707_00062;MGYG000002528_00366;MGYG000001374_01835;MGYG000001461_01243;MGYG000000181_00012;MGYG000001739_01299;MGYG000003921_00578;MGYG000000404_00343;MGYG000002966_00074;MGYG000000231_00609;MGYG000004271_00555;MGYG000002120_01321;MGYG000000002_02119;MGYG000002186_02387;MGYG000003431_02005;MGYG000003702_00926;MGYG000000359_00927;MGYG000003363_01096;MGYG000000003_00285;MGYG000004828_01577;MGYG000000258_00429;MGYG000000170_00153;MGYG000002716_01347;MGYG000000154_00118;MGYG000001529_02777;MGYG000000378_01265;MGYG000004185_02169;MGYG000004740_01467;MGYG000003937_01847;MGYG000004006_01975;MGYG000003926_00185;MGYG000000037_01258;MGYG000004532_01918;MGYG000000806_01931;MGYG000004733_01784;MGYG000000263_01340;MGYG000000142_01978;MGYG000000087_02748;MGYG000000212_01475;MGYG000001617_03190;MGYG000000501_00895;MGYG000002974_01419;MGYG000002992_00163;MGYG000003279_01634;MGYG000002395_00974;MGYG000001338_02546;MGYG000000383_00714;MGYG000001602_01804;MGYG000003681_00986;MGYG000000164_00799;MGYG000002105_00517;MGYG000003452_00954;MGYG000002281_01909;MGYG000000375_01448;MGYG000002084_00948;MGYG000000217_00276;MGYG000000584_00984;MGYG000004468_00582;MGYG000004493_00203;MGYG000002707_01010;MGYG000002574_00010;MGYG000000200_02456;MGYG000003683_00472;MGYG000001310_02091;MGYG000003542_01331;MGYG000000044_00323;MGYG000000018_00079;MGYG000000050_00594;MGYG000000118_02693;MGYG000000080_03114;MGYG000000953_00944;MGYG000002549_02739;MGYG000003891_01912;MGYG000002279_00558;MGYG000002438_03839;MGYG000000139_00882;MGYG000002787_01666;MGYG000001327_01861;MGYG000004501_00310;MGYG000004876_02584;MGYG000003409_01919;MGYG000002445_01919;MGYG000001334_01648;MGYG000001489_04176;MGYG000000196_04506;MGYG000004250_00307;MGYG000000301_01011;MGYG000001661_02348;MGYG000001199_01004;MGYG000004791_00980;MGYG000000204_00777;MGYG000002072_00619;MGYG000001635_02145;MGYG000001319_00347;MGYG000000074_02205;MGYG000001157_01540;MGYG000002155_01252;MGYG000000414_01789;MGYG000004519_00424;MGYG000000187_02265;MGYG000000013_01224;MGYG000000171_00851;MGYG000001292_01114;MGYG000000467_01931;MGYG000002485_02479;MGYG000000175_00766;MGYG000002455_00199;MGYG000000398_00287;MGYG000000249_01353;MGYG000001683_01828;MGYG000004893_01505;MGYG000000271_03251;MGYG000000089_01321;MGYG000000562_01219;MGYG000000084_00216;MGYG000000133_02282;MGYG000003252_01520;MGYG000004735_01945;MGYG000002109_01277;MGYG000002298_02411;MGYG000002098_01090;MGYG000002289_02222;MGYG000002949_03160;MGYG000001141_01007;MGYG000004594_01443 domain d__Bacteria 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H2GV@909932|Negativicutes 0.13194444444444445 186801|Clostridia 0.5 F 0.5208333333333334 Belongs to the phosphoglycerate kinase family 0.5 pgk 0.9930555555555556 - 0.9305555555555556 2.7.2.3,5.3.1.1 0.6805555555555556 ko:K00927,ko:K01803 0.6805555555555556 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6805555555555556 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9930555555555556 R01015,R01512 0.6805555555555556 RC00002,RC00043,RC00423 0.6805555555555556 ko00000,ko00001,ko00002,ko01000,ko04147 0.9930555555555556 - 1.0 - 1.0 - 0.9652777777777778 PGK,TIM 0.6736111111111112 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003694_01736 0.006944444444444444 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 0.6805555555555556 0.6805555555555556 0.6805555555555556 0.6805555555555556 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6805555555555556 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 0.6805555555555556 none 1.0 1812213 1888248 1138396 1797989 1744448 1530037 2140715 1766184 1874087 1764647 4357615 2013435 1545331 2174164 1788549 2218454 1714517 814445 1552038 1838935 2258227 1869313 1330597 2353038 1751139 1891096 1936322 924820 1961745 1964442 1793886 2385802 1516688 2230232 2043372 1820517 2247650 1392699 3035754 1920770 2748568 2380253 2573448 2039756 1985698 3124713 2887617 3517251 3785975 3776768 1833376 3028755 2956128 2505860 2678097 3489152 2286425 2404666 4263643 2564323 934052 1699648 2587014 2685777 2520765 1762119 2291874 2987042 1522114 2248167 2268770 2399448 3144281 2751671 2854879 2975356 2610276 2146374 3308137 2566884 4367167 3191036 3724149 2660178 0 2483370 5091675 2596871 2375712 3102024 2403220 2948845 2980514 5442549 2312777 2514961 3725705 2504890 4539107 4008021 2568981 2349579 2492347 3459167 3152536 3430716 3793351 3128510 2836790 2330152 1462407 3455533 2579393 3174587 3055982 2765078 2983003 2638664 3018746 3001746 3383231 2877966 2896883 3483065 4246752 4039655 3766582 2538675 3097035 4049489 2687263 2620506 2785516 2738489 5053034 2183227 2597390 0 2617892 2801265 2844389 2889658 2738301 3885098 0 3126311 2812530 3531452 3254101 3750187 3251341 2450882 2766927 2844585 2164887 2740522 5349829 3974579 0 3984868 3299346 3082748 4631825 6172193 3561908 1770284 2751991 3636763 2926387 4372589 2444830 3575384 6383143 3762087 2933181 2974063 2564540 2102309 2408977 2994912 2613710 7123104 2261309 4389407 1453576 3198584 0 2132524 2597741 2190677 +AALPTLKK MGYG000004468_00582;MGYG000000038_02186;MGYG000003922_03393;MGYG000000262_01196;MGYG000000415_01539;MGYG000001310_02091;MGYG000000044_00323;MGYG000004727_00660;MGYG000002528_00366;MGYG000002549_02739;MGYG000002279_00558;MGYG000002438_03839;MGYG000000139_00882;MGYG000000404_00343;MGYG000003921_00578;MGYG000004271_00555;MGYG000000002_02119;MGYG000004876_02584;MGYG000003702_00926;MGYG000002445_01919;MGYG000003363_01096;MGYG000001489_04176;MGYG000000196_04506;MGYG000000301_01011;MGYG000000003_00285;MGYG000000258_00429;MGYG000001661_02348;MGYG000000170_00153;MGYG000004185_02169;MGYG000004740_01467;MGYG000003937_01847;MGYG000000074_02205;MGYG000000414_01789;MGYG000003926_00185;MGYG000004733_01784;MGYG000000142_01978;MGYG000000087_02748;MGYG000000212_01475;MGYG000000013_01224;MGYG000001617_03190;MGYG000000171_00851;MGYG000002455_00199;MGYG000003279_01634;MGYG000001683_01828;MGYG000001338_02546;MGYG000000271_03251;MGYG000001602_01804;MGYG000000164_00799;MGYG000002105_00517;MGYG000000084_00216;MGYG000000133_02282;MGYG000004735_01945;MGYG000002109_01277;MGYG000002098_01090;MGYG000000584_00984 domain d__Bacteria 1.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H2GV@909932|Negativicutes 0.18181818181818182 186801|Clostridia 0.41818181818181815 G 0.5272727272727272 Belongs to the phosphoglycerate kinase family 0.5636363636363636 pgk 1.0 - 1.0 2.7.2.3,5.3.1.1 0.6 ko:K00927,ko:K01803 0.6 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 0.6 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01015,R01512 0.6 RC00002,RC00043,RC00423 0.6 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGK,TIM 0.6 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00582 0.01818181818181818 phosphoglycerate kinase. | triose-phosphate isomerase. triose phosphoisomerase. - (2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP. | D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate. 0.6 0.6 0.6 0.6 Glycolysis / Gluconeogenesis|Fructose and mannose metabolism|Inositol phosphate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 0.6 K00927:PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]|K01803:TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1] 0.6 none 1.0 1020952 0 542599 0 813214 0 929407 0 0 0 1637533 748985 0 1129956 0 0 0 267411 0 0 885593 0 553273 0 0 563269 0 363202 0 817780 0 1294088 760232 1176012 0 0 854028 778869 1323029 0 1328949 0 904606 0 627902 0 0 0 1409094 409335 0 997710 0 0 0 0 0 0 1108044 0 321287 0 0 974639 0 0 0 1032030 0 1385384 1176556 1250288 0 0 1516989 1132962 799035 0 1481099 0 1873663 0 1369727 0 0 0 2054605 1006891 0 1102162 0 0 0 2147274 0 0 1324295 0 1623134 0 0 739437 0 1516658 0 1086241 0 946838 1113817 1004607 0 0 1254248 1329324 950545 0 946772 0 864877 0 701816 0 0 0 1307026 1510230 0 689795 0 0 0 550157 0 0 1963849 0 681630 0 0 1684660 0 600381 0 1170866 0 1128052 846463 1125141 0 0 1009647 146931 907827 0 868141 0 1612280 0 975031 0 0 0 2990143 1758329 0 534328 0 0 0 1849918 0 0 1868706 0 1870697 0 0 1443681 0 721673 0 2533198 0 2145754 613877 1553180 0 0 1201718 1122835 +AALQAEIDANNAAVK MGYG000002720_01061 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3WHDD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) 1.0 serS 1.0 - 1.0 6.1.1.11 1.0 ko:K01875 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03662,R08218 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Seryl_tRNA_N,tRNA-synt_2b 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01061 1.0 serine--tRNA ligase. seryl-tRNA synthetase. This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1. (1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl- tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl- tRNA(Sec). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01875:SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11] 1.0 none 1.0 0 0 0 0 0 339407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311657 0 76825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470513 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477689 0 331287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94807 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104566 0 83123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALQDEFGLNKDGSPVMAMVTR MGYG000003937_01118 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3WGRA@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Synthesizes alpha-1,4-glucan chains using ADP-glucose 1.0 glgA 1.0 - 1.0 2.4.1.21 1.0 ko:K00703 1.0 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 1.0 M00565 1.0 R02421 1.0 RC00005 1.0 ko00000,ko00001,ko00002,ko01000,ko01003 1.0 - 1.0 GT5 1.0 - 1.0 Glyco_transf_5,Glycos_transf_1,HC2 1.0 2.4.1.21 1.0 GT5 1.0 GT5 1.0 GT5 1.0 MGYG000003937_01118 1.0 starch synthase. starch (bacterial glycogen) synthase. The description (accepted name) varies according to the source of the enzyme and the nature of its synthetic product, e.g. starch synthase, bacterial glycogen synthase.-!-A similar enzyme utilizes UDP-alpha-D-glucose (cf. EC 2.4.1.11). [(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1->4)-alpha-D- glucosyl](n+1) + ADP + H(+). 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biofilm formation - Escherichia coli 1.0 K00703:glgA; starch synthase [EC:2.4.1.21] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALQGASLNVYINTK MGYG000001338_02421;MGYG000000184_03366;MGYG000000200_00062 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Methenyltetrahydrofolate cyclohydrolase 1.0 fchA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 FTCD_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02421 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 283728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 647277 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 960626 322402 0 0 0 0 0 0 0 819199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 638742 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 778052 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 503148 529859 0 0 0 0 0 0 +AALQLK MGYG000000084_00626;MGYG000003937_01088;MGYG000001346_00290;MGYG000001531_02895 domain d__Bacteria 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,3WH8V@541000|Ruminococcaceae 0.5 186801|Clostridia 0.75 C 0.75 Psort location Cytoplasmic, score 0.75 - 0.75 - 0.5 1.3.1.108 0.75 ko:K03521,ko:K22431 0.5 - 0.75 - 1.0 - 0.75 - 0.75 ko00000,ko01000 0.75 - 1.0 - 1.0 - 1.0 ETF 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000084_00626 0.25 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 0.75 0.75 0.75 0.75 - 0.75 K03521:fixA, etfB; electron transfer flavoprotein beta subunit|K22431:carD; caffeyl-CoA reductase-Etf complex subunit CarD [EC:1.3.1.108] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1146819 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2784725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALQQVK MGYG000002455_03412 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG0457@1|root,COG0457@2|Bacteria,4NF7U@976|Bacteroidetes,2FP0S@200643|Bacteroidia,4AKR5@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_12,TPR_16,TPR_19,TPR_2,TPR_3,TPR_6,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_03412 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1537545 0 0 0 0 1057616 0 0 0 0 958815 0 0 0 0 0 0 0 0 0 0 +AALQQVVEQYHPDR MGYG000000022_02863;MGYG000002545_01583;MGYG000002274_00511 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,3WGTH@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 CobW/HypB/UreG, nucleotide-binding domain 1.0 cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CobW_C,cobW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_02863 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 614815 0 0 0 0 489003 0 0 0 0 463630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1023113 0 0 0 0 1143109 0 0 0 0 809431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1589409 0 0 0 0 1961693 0 0 0 0 1560005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 441745 0 0 0 0 490939 0 0 0 0 419853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1706144 0 0 0 0 2059329 0 0 0 0 2214645 0 0 0 0 0 0 0 0 0 0 +AALQTAEANVAAAK MGYG000002867_01551;MGYG000000074_00445;MGYG000001415_00462;MGYG000000053_00168 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,2FN62@200643|Bacteroidia,22UYI@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family 1.0 - 1.0 - 1.0 - 1.0 ko:K03585 1.0 ko01501,ko01503,map01501,map01503 1.0 M00646,M00647,M00699,M00718 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 1.0 2.A.6.2,8.A.1.6 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002867_01551 0.25 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|Cationic antimicrobial peptide (CAMP) resistance 1.0 K03585:acrA, mexA, adeI, smeD, mtrC, cmeA; membrane fusion protein, multidrug efflux system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 498095 354492 359793 539073 348111 0 368696 331247 641736 464332 349504 0 312525 387223 457304 222233 0 0 0 451779 1098183 228671 0 0 198226 564878 276825 0 636311 1205819 228385 221427 274327 0 0 417324 585792 0 0 0 0 601036 0 729585 455037 0 0 0 0 0 0 524283 0 0 0 0 0 0 482076 0 0 488681 0 0 0 0 0 821259 0 0 446474 0 0 298280 0 320699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 833478 0 0 0 0 0 0 0 0 0 1744926 1201267 2020095 3224336 2239399 2281082 2297465 1658313 2922699 1943856 1291649 0 1623727 1642906 1877184 1889104 2746951 0 0 2925183 2341238 1657799 0 1688501 1779938 2085881 1525235 0 1618276 5103309 1666283 1363777 335403 0 0 2672699 2621845 2212462 +AALQTAEANVEAAK MGYG000000003_02125 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG0845@1|root,COG0845@2|Bacteria,4NEXN@976|Bacteroidetes,2FN62@200643|Bacteroidia,22UYI@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family 1.0 - 1.0 - 1.0 - 1.0 ko:K03585 1.0 ko01501,ko01503,map01501,map01503 1.0 M00646,M00647,M00699,M00718 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01504,ko02000,ko03036 1.0 2.A.6.2,8.A.1.6 1.0 - 1.0 - 1.0 Biotin_lipoyl_2,HlyD_3,HlyD_D23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_02125 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|Cationic antimicrobial peptide (CAMP) resistance 1.0 K03585:acrA, mexA, adeI, smeD, mtrC, cmeA; membrane fusion protein, multidrug efflux system 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2517670 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1418963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 509394 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405285 0 0 0 0 0 0 0 0 +AALQTNSFMSAASFQETTK MGYG000002438_02330 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,22VWB@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000002438_02330 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519387 0 0 0 0 0 0 0 0 +AALQTSSFMSAASFQETTK MGYG000001789_00145;MGYG000000196_03983;MGYG000002549_02931;MGYG000000236_01798;MGYG000004763_01698;MGYG000001345_04693;MGYG000001346_01525;MGYG000001313_00088 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000001789_00145 0.125 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 813353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641710 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALQVVK MGYG000002528_02344;MGYG000000028_01311 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 phosphate acetyltransferase 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_02344 0.5 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00625:pta; phosphate acetyltransferase [EC:2.3.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 898269 0 0 0 0 606365 0 0 0 0 789466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1633539 0 0 1984692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 998948 0 0 0 0 0 0 0 0 0 0 0 0 0 1050968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1082763 0 0 0 0 468717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALREDPDVILVGEMR MGYG000001319_00715;MGYG000000089_01669 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,4BWDG@830|Butyrivibrio 0.5 186801|Clostridia 1.0 NU 1.0 Type II/IV secretion system protein 0.5 pilT 1.0 - 1.0 - 1.0 ko:K02669 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02035,ko02044 1.0 3.A.15.2 1.0 - 1.0 - 1.0 T2SSE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001319_00715 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02669:pilT; twitching motility protein PilT 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1015144 0 0 0 0 1808535 0 0 0 0 1367579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALSDYYR MGYG000001300_01631;MGYG000001255_00890;MGYG000002641_02297;MGYG000003899_00049;MGYG000002274_00762;MGYG000000022_02058 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3WITG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Fe-S iron-sulfur cluster assembly protein, NifU family 1.0 nifU 1.0 - 1.0 - 1.0 ko:K04488 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 NifU_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_01631 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04488:iscU, nifU; nitrogen fixation protein NifU and related proteins 1.0 none 1.0 0 391497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 727603 0 0 0 0 555044 0 0 0 0 534882 0 0 0 0 0 0 0 0 0 0 0 535105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1380726 0 0 0 0 1495577 0 0 0 0 1159639 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1341850 0 0 0 0 1077488 0 0 0 0 1010613 0 0 0 0 0 0 0 0 0 0 0 762680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 858425 0 0 0 0 909896 0 0 0 0 696484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 937169 0 0 0 0 991801 0 0 0 0 699291 0 0 0 0 0 0 0 0 0 0 +AALSMTIPTGTGIHR MGYG000000196_02404;MGYG000004876_03241;MGYG000000236_00877;MGYG000000170_02306 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0673@1|root,COG0673@2|Bacteria,4NGP9@976|Bacteroidetes,2FMTZ@200643|Bacteroidia,4AKIQ@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 E 1.0 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate 1.0 ddh 0.75 - 1.0 1.4.1.16 1.0 ko:K03340 1.0 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 1.0 M00526 1.0 R02755 1.0 RC00006 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding,DAPDH_C,GFO_IDH_MocA,NAD_binding_3,Semialdhyde_dh 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_02404 0.25 diaminopimelate dehydrogenase. meso-diaminopimelate D-dehydrogenase. - H2O + meso-2,6-diaminoheptanedioate + NADP(+) = (S)-2-amino-6- oxoheptanedioate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K03340:dapdh; diaminopimelate dehydrogenase [EC:1.4.1.16] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 935157 0 0 1931573 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1089755 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 664869 0 0 1448544 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 639370 0 0 0 0 0 0 0 0 +AALSMTIPTGTGIHRR MGYG000000196_02404;MGYG000004876_03241;MGYG000000236_00877;MGYG000000170_02306 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0673@1|root,COG0673@2|Bacteria,4NGP9@976|Bacteroidetes,2FMTZ@200643|Bacteroidia,4AKIQ@815|Bacteroidaceae 0.75 976|Bacteroidetes 1.0 E 1.0 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate 1.0 ddh 0.75 - 1.0 1.4.1.16 1.0 ko:K03340 1.0 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 1.0 M00526 1.0 R02755 1.0 RC00006 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_binding,DAPDH_C,GFO_IDH_MocA,NAD_binding_3,Semialdhyde_dh 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_02404 0.25 diaminopimelate dehydrogenase. meso-diaminopimelate D-dehydrogenase. - H2O + meso-2,6-diaminoheptanedioate + NADP(+) = (S)-2-amino-6- oxoheptanedioate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K03340:dapdh; diaminopimelate dehydrogenase [EC:1.4.1.16] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 505557 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 959336 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALSNSFC(Carbamidomethyl)EVSLQPYGVFTHR MGYG000002494_01895 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0002@1|root,COG0002@2|Bacteria,1MVJ6@1224|Proteobacteria,1RNMX@1236|Gammaproteobacteria,3XM7I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde 1.0 argC 1.0 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.2.1.38 1.0 ko:K00145 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028,M00845 1.0 R03443 1.0 RC00684 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iSSON_1240.SSON_4131 1.0 AA_kinase,Semialdhyde_dh,Semialdhyde_dhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_01895 1.0 N-acetyl-gamma-glutamyl-phosphate reductase. NAGSA dehydrogenase. - N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00145:argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38] 1.0 none 1.0 0 0 0 0 0 249616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253632 0 292898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1251469 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1666923 0 993197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALSNTFGFGGHNAC(Carbamidomethyl)AIVK MGYG000002438_01705 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,2FNDB@200643|Bacteroidia,22W73@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP 1.0 fabF 1.0 - 1.0 2.3.1.179 1.0 ko:K09458 1.0 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 1.0 M00083,M00572 1.0 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 1.0 RC00039,RC02728,RC02729,RC02888 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 Ketoacyl-synt_C,ketoacyl-synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01705 1.0 beta-ketoacyl-[acyl-carrier-protein] synthase II. KAS II. Involved in the dissociated (or type II) fatty acid biosynthesis system that occurs in plants and bacteria.-!-While the substrate specificity of this enzyme is very similar to that of EC 2.3.1.41, it differs in that palmitoleoyl-ACP is not a good substrate of EC 2.3.1.41 but is an excellent substrate of this enzyme.-!-The fatty-acid composition of Escherichia coli changes as a function of growth temperature, with the proportion of unsaturated fatty acids increasing with lower growth temperature.-!-Controls the temperature-dependent regulation of fatty-acid composition, with mutants lacking this acivity being deficient in the elongation of palmitoleate to cis-vaccenate at low temperatures. (9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)- octadecenoyl-[ACP] + CO2 + holo-[ACP]. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis|Biotin metabolism|Metabolic pathways|Fatty acid metabolism 1.0 K09458:fabF, OXSM, CEM1; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90739 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 827236 0 0 0 0 0 0 +AALSNTFGFGGHNAC(Carbamidomethyl)VIVK MGYG000000042_00641;MGYG000000243_01872;MGYG000001306_02492 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0304@1|root,COG0304@2|Bacteria,4NEKC@976|Bacteroidetes,2FNDB@200643|Bacteroidia,4ANNA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP 1.0 fabF 1.0 - 1.0 2.3.1.179 1.0 ko:K09458 1.0 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 1.0 M00083,M00572 1.0 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 1.0 RC00039,RC02728,RC02729,RC02888 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 Ketoacyl-synt_C,ketoacyl-synt 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_00641 0.3333333333333333 beta-ketoacyl-[acyl-carrier-protein] synthase II. KAS II. Involved in the dissociated (or type II) fatty acid biosynthesis system that occurs in plants and bacteria.-!-While the substrate specificity of this enzyme is very similar to that of EC 2.3.1.41, it differs in that palmitoleoyl-ACP is not a good substrate of EC 2.3.1.41 but is an excellent substrate of this enzyme.-!-The fatty-acid composition of Escherichia coli changes as a function of growth temperature, with the proportion of unsaturated fatty acids increasing with lower growth temperature.-!-Controls the temperature-dependent regulation of fatty-acid composition, with mutants lacking this acivity being deficient in the elongation of palmitoleate to cis-vaccenate at low temperatures. (9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)- octadecenoyl-[ACP] + CO2 + holo-[ACP]. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis|Biotin metabolism|Metabolic pathways|Fatty acid metabolism 1.0 K09458:fabF, OXSM, CEM1; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406558 0 0 0 0 612185 0 0 0 0 307246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2035800 0 0 0 0 1405032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256574 0 0 0 0 333434 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 933262 0 0 0 0 669591 0 0 0 0 564026 0 0 0 0 0 0 0 0 0 0 +AALTADAIAK MGYG000004594_00959;MGYG000004735_00207;MGYG000001698_00702 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.3333333333333333 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.6666666666666666 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000004594_00959 0.3333333333333333 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10660147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2698179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALTADDIAK MGYG000000142_02834;MGYG000000463_01481;MGYG000002298_01806;MGYG000000140_01464;MGYG000000171_00241;MGYG000004733_01907;MGYG000000268_00698;MGYG000003450_00463;MGYG000003819_01577;MGYG000000031_02405;MGYG000000249_01089;MGYG000001619_00896;MGYG000004517_00262;MGYG000002926_01683;MGYG000000252_02480;MGYG000001315_01921;MGYG000000089_02490;MGYG000000127_02901;MGYG000001310_01399;MGYG000004296_00104 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.55 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.75 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000142_02834 0.05 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 6614630 6635460 7871410 3838188 8021079 11179069 2723887 8705793 4701067 5854881 10184453 6880191 8045078 5435754 8310964 7698876 5821439 13505742 5235494 7305265 6274004 8909107 12433936 5147840 7905061 5821353 5465947 10370721 5905542 4724936 4223711 5250986 6582859 6322648 6358126 4279474 6082012 8845629 0 9594387 8639244 6434491 7616748 4741382 8210311 8301897 6444160 6125274 6755039 3527922 8210378 0 4666758 4597815 16168082 12341899 5959648 8363509 5799110 0 6301328 8794603 7506471 6147958 7711884 8857986 9735523 5580797 13730163 8260531 0 9528051 9651174 0 7185507 12391392 0 6829234 7616711 9197161 4137743 7406100 7821518 9199418 7794358 0 5416026 6503133 6767122 10089619 11367985 8512583 0 6660334 9646899 0 7819739 13488577 11728881 7589681 10154483 8388645 10620581 8297703 0 9076638 7996990 8798166 9533083 11897641 0 6841810 10095103 8251450 3094468 3649301 6444872 3355890 3943780 3308034 3409865 3253944 2632578 3786485 3418256 6035140 5415059 3250832 3016547 4766367 9642959 2850910 2658334 3679156 2538732 3714382 1902008 3162173 2298991 2002765 3251063 8578137 7175466 2554610 4869106 2804437 7295997 546083 3370743 3151139 2093998 7987365 4892029 2917070 0 5236186 2690219 6010043 0 6410365 4012194 4893956 3449533 4008816 1759423 6172880 5054932 3409616 4216773 3967505 5900515 3412480 4554180 7319653 6527187 6263969 4542911 5814091 4860628 7448211 5998071 1864261 5247607 3537946 12228404 5435416 5584707 4393312 3139058 8433338 +AALTADEIAK MGYG000004221_00458;MGYG000002229_00282;MGYG000002006_01658;MGYG000004482_00393;MGYG000002079_00687;MGYG000004667_00970;MGYG000002727_00240;MGYG000001319_00729;MGYG000000115_00663;MGYG000002609_02142;MGYG000002143_00035;MGYG000002057_00345;MGYG000000728_00587;MGYG000002247_01703;MGYG000003116_01723;MGYG000003503_00176;MGYG000004726_03204;MGYG000001531_01607;MGYG000001136_01739;MGYG000003581_02331;MGYG000001374_00487;MGYG000001577_00663;MGYG000004663_01541;MGYG000002393_00923;MGYG000000352_00288;MGYG000004380_01725;MGYG000004475_00310;MGYG000000242_00224;MGYG000000212_00440;MGYG000002139_00077;MGYG000004764_00308;MGYG000001665_01593;MGYG000000076_02377;MGYG000004526_01655;MGYG000001699_00078;MGYG000001607_01964;MGYG000000159_02392;MGYG000001756_01779;MGYG000000387_01345;MGYG000000187_00493;MGYG000000184_00575;MGYG000004784_01123;MGYG000001439_01567;MGYG000000371_01679;MGYG000000806_02014;MGYG000004743_00400;MGYG000000489_00801;MGYG000000915_00888;MGYG000002035_01821;MGYG000002099_01951;MGYG000004487_00114;MGYG000002159_01291;MGYG000000278_00304;MGYG000000417_00539;MGYG000000280_02154;MGYG000004785_01840;MGYG000000154_00436;MGYG000000245_03386;MGYG000002831_00019;MGYG000002753_00264;MGYG000002707_01357;MGYG000000036_01410;MGYG000000045_00432;MGYG000000146_01902;MGYG000001707_02428;MGYG000003504_01005;MGYG000001497_00744;MGYG000000217_00686;MGYG000002091_01028;MGYG000002194_01689;MGYG000000099_03199;MGYG000000194_03193;MGYG000002934_01311;MGYG000002845_01363;MGYG000002945_01502;MGYG000003583_00265;MGYG000000982_00638;MGYG000000133_02955;MGYG000003589_01762;MGYG000004634_00605;MGYG000002596_00549;MGYG000003142_00686;MGYG000000201_02673;MGYG000000251_01169;MGYG000004558_03187;MGYG000000153_02081;MGYG000001748_00979;MGYG000003821_02000;MGYG000004810_00381;MGYG000001338_02151;MGYG000000164_00358;MGYG000001356_00630;MGYG000002966_02744;MGYG000003656_02122;MGYG000000231_00504;MGYG000003432_00750 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.3125 186801|Clostridia 0.9583333333333334 G 1.0 Belongs to the PEP-utilizing enzyme family 0.7291666666666666 ppdK 0.9895833333333334 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9791666666666666 - 1.0 - 1.0 - 1.0 GT1 0.9583333333333334 MGYG000004221_00458 0.010416666666666666 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 15322117 15947122 8069399 13104146 15440742 14360621 11816614 14438851 12403133 14599870 14332606 16444696 12567218 13342117 19523828 13329003 12404819 37003827 11096534 16638700 16773826 12534844 35201681 8751980 19008478 12423424 12029167 30067516 16487426 16068151 6602567 12464599 6713901 16300579 12866323 11542396 15984616 8422338 9228146 20729610 4811656 6770031 7671798 4693566 7218786 8422204 6667753 6344518 5461457 8545428 5432363 5744181 4377035 3271641 5273025 17795673 5499945 7747384 6737930 3178253 10217873 7287843 6328940 5654441 7435780 14361113 9643144 6311618 20983702 10450304 5280731 8164363 8702527 8107157 6834779 6487818 16401655 22440588 12860267 12516277 9532888 9818784 12897715 13518977 12604726 12404096 12928621 15225896 12048987 15713650 16139331 14143847 16497896 10222303 14090887 12155634 15496257 13367665 15633482 9867381 15352049 12818497 16077999 10928889 12387217 17814583 14011438 20843986 18183676 13973400 8550908 12498474 14135522 13389138 7450695 26635232 8948558 6834179 14783831 7824801 6917466 5748919 6147839 7757605 9870555 10308619 10641638 6210787 6469700 9821575 8956453 11619346 4628103 7322612 7834141 7490704 7192692 9494124 5382816 4845542 6839526 14127096 16546089 7559444 21014255 16655206 10761410 4095555 5636762 7023164 5289567 11908230 16743705 39481799 23562525 22627792 9163546 9806589 22699706 15251496 12149854 17543257 16549396 17821810 11303925 22323533 17209521 16145215 13210678 12126260 15638093 7028513 18337458 13462061 21452256 9613376 14134774 20061714 17451425 24268501 21596565 5139748 24564627 35414907 32908526 15576347 11826488 15653180 8476914 16075913 +AALTADEVAK MGYG000002026_01365 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__HGM13010|s__HGM13010 sp900754965|m__MGYG000002026 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002026_01365 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9191386 0 0 0 6860415 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALTADR MGYG000002438_03578;MGYG000000236_00181;MGYG000001378_01176;MGYG000000044_00817;MGYG000001489_03803;MGYG000000013_03892;MGYG000000196_02017;MGYG000000222_00273;MGYG000001661_00974;MGYG000000696_02522;MGYG000001780_04079;MGYG000002549_01561;MGYG000001313_01473;MGYG000003681_00659;MGYG000002455_03526;MGYG000001346_03147;MGYG000003363_02147;MGYG000000098_03346;MGYG000001345_02795;MGYG000004763_00142 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 0.8 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002438_03578 0.05 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 2721396 2475699 2213099 3459999 2837374 2131496 3180300 2482298 3058525 2658800 3042925 0 2455162 3211384 3137856 2665603 2609921 1393228 2917882 252749 0 2939232 2702882 3846639 3105497 3501996 3281852 1936168 3365779 4035576 3597935 3519789 3063371 5266325 4210376 3136355 3652026 2035231 3724872 2871114 3111194 5166572 3981352 4116178 3937627 5039533 3727354 4791364 4580910 5652700 3766847 5254687 6118761 3818458 4636054 1663563 5541654 5484648 0 4253164 0 4212310 4481729 5291562 4427783 1403825 3473151 4542581 3081181 3978003 2989471 5176278 3889438 5063534 5713858 3263482 1863003 2187630 2895226 2548581 3145079 3303217 2948226 1284158 3212247 3311651 3926587 3247762 2710801 3147903 536330 2643708 2187806 0 2264800 2555488 0 1811275 2598724 4024934 3004892 2919740 1017675 2006795 4248868 2887504 3575327 1972044 1032149 2213827 2636198 3233057 3060440 3083299 3393719 2893296 3325948 2785589 3022764 0 2739270 3028325 2532037 2540547 2155411 0 0 3096088 2386647 3164334 2948247 2900961 3550743 3098139 0 2491467 318996 4044769 2667923 3188821 2438266 1003634 2103635 3678137 4554360 3131444 2440863 4811160 3118640 1909093 3364330 4259490 2582058 1730282 1810685 2181745 3301469 2275295 2099278 1866812 2373378 2060235 4791159 2241518 3763847 1641423 2186663 1958779 1887325 3186245 2149312 3374459 0 2144075 2562995 3652415 3297386 3461736 2230021 1882975 1728969 2583675 2448174 3363273 1507741 2464160 3935292 2109360 3116231 1907114 +AALTAGDIAK MGYG000002274_02693;MGYG000002040_00906 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002274_02693 0.5 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6489860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALTAGEIAK MGYG000004866_01031;MGYG000000022_02788;MGYG000001157_01952;MGYG000003899_02226;MGYG000003921_00033;MGYG000003166_00833;MGYG000000084_02524;MGYG000000636_01370;MGYG000002545_01217;MGYG000002138_00950;MGYG000002105_00879;MGYG000002224_02000;MGYG000001300_02837;MGYG000001255_00900;MGYG000004732_02304;MGYG000000039_02141 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 0.9375 MGYG000004866_01031 0.0625 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 15879569 14940597 14009059 9661172 0 0 0 0 0 13426359 0 0 0 0 0 0 26949003 0 15137821 0 0 19849464 0 0 0 10948460 22592941 0 0 0 0 0 0 10130601 0 11417793 0 21248984 15218651 16129741 0 0 13544483 19348327 0 0 0 0 0 0 0 0 0 15558878 13735906 20284958 0 0 0 13314242 0 0 0 0 13927951 0 0 0 0 0 0 0 0 0 0 0 7475413 0 8254447 0 6757340 7821345 6903940 8064878 0 9862082 10122030 7935172 8299966 0 7543979 6578837 18281764 0 0 9189702 7617699 18791233 0 0 7495908 8326641 18432348 0 0 0 7116811 6047281 0 0 7186398 8516285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5075204 0 0 0 0 0 0 2512846 0 0 3455859 0 0 3230543 17866147 0 0 0 4079368 21320014 0 0 0 0 22837648 4735103 0 0 0 0 2378242 0 0 0 0 +AALTANR MGYG000000243_00277;MGYG000001789_01569;MGYG000004797_01193;MGYG000003542_00399;MGYG000002218_01508;MGYG000001787_02320;MGYG000002478_03849 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000243_00277 0.14285714285714285 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 4042176 0 4040478 5534784 4517617 3537746 4420009 3384915 5135435 0 7041850 0 0 0 4644218 7679282 5220223 4304843 4891651 3662156 8633583 4029043 6262833 6016238 0 5139571 7424425 6171756 0 5301601 10140457 5516770 9068816 0 4850878 6055930 6187628 5887184 0 0 0 0 0 0 0 0 0 0 2791478 0 0 0 0 0 0 993566 0 0 0 0 2441781 0 0 0 0 2375130 0 0 9322221 0 0 0 21050431 0 0 0 461169 0 0 81594 7106958 6348590 0 414880 987185 0 5668698 0 0 0 83420 2605602 531825 331873 207422 631883 422847 450241 4600085 6835932 0 0 0 8032329 0 0 4227260 443973 434829 0 642713 6382796 1406488 557543 0 0 0 0 625935 0 427966 0 0 0 415835 0 0 0 70657 0 0 0 140068 0 259233 0 0 0 0 468048 121567 1639159 0 67852 0 0 0 0 0 83197 0 359254 0 0 469142 1485786 2386128 1646634 0 635748 2502057 0 1341110 0 0 0 0 2161299 1147347 4315129 1395470 1527550 0 1270163 2797352 1474045 0 2153959 0 1342915 0 431680 0 0 0 0 2942873 2117635 3348757 1095987 +AALTNMEGDPIAPAVAEAGER MGYG000001302.1_01910 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG0526@1|root,COG0526@2|Bacteria,4NNXC@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 CO 1.0 Outer membrane protein Omp28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Cleaved_Adhesin,Omp28,Thioredoxin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_01910 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 757263 1037856 721117 0 0 0 0 0 0 0 0 0 0 0 0 656224 1797390 0 0 0 740881 0 0 0 0 981177 0 0 0 0 755781 0 0 0 0 758689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 665859 554723 734449 0 0 0 0 0 0 0 0 0 0 0 0 976277 1026469 0 0 0 784931 0 0 0 0 847938 0 0 0 0 633520 0 0 0 0 724812 0 0 398092 0 381547 0 0 0 0 0 0 0 0 0 0 0 0 1039909 721252 0 0 0 1615985 0 0 0 0 1046319 0 0 0 0 383852 0 0 0 0 400855 0 0 0 429361 349984 0 0 0 0 0 0 0 0 0 0 0 0 696913 451571 0 0 0 710431 0 0 0 0 587242 0 0 0 0 0 0 0 0 0 0 +AALTSVMHR MGYG000002478_00538;MGYG000004797_03071 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4225@1|root,COG4289@1|root,COG4225@2|Bacteria,COG4289@2|Bacteria,4NEU3@976|Bacteroidetes,2G2NU@200643|Bacteroidia,4AKRX@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 protein conserved in bacteria 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF2264,Glyco_hydro_88 1.0 3.2.1.- 1.0 GH105 1.0 GH105 1.0 GH105+GH154 1.0 MGYG000002478_00538 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 962905 0 0 0 0 534179 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALTVAISTIESASSK MGYG000002517_01116 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 16S ribosomal RNA 1.0 rpsT 1.0 - 1.0 - 1.0 ko:K02968 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S20p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01116 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02968:RP-S20, rpsT; small subunit ribosomal protein S20 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 195744 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 272379 0 0 0 0 315004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1882079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6950405 +AALVGLTK MGYG000000278_01407 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA3402|s__UBA3402 sp003478355|m__MGYG000000278 1.0 COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4CYEK@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 IQ 1.0 Enoyl-(Acyl carrier protein) reductase 1.0 - 1.0 - 1.0 1.1.1.100 1.0 ko:K00059 1.0 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 1.0 M00083,M00572 1.0 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 1.0 RC00029,RC00117 1.0 ko00000,ko00001,ko00002,ko01000,ko01004 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000278_01407 1.0 3-oxoacyl-[acyl-carrier-protein] reductase. - Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates. a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH. 1.0 1.0 1.0 1.0 Fatty acid biosynthesis|Prodigiosin biosynthesis|Biotin metabolism|Biosynthesis of unsaturated fatty acids|Metabolic pathways|Fatty acid metabolism 1.0 K00059:fabG, OAR1; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4189614 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4521521 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALVHGLK MGYG000002528_01864;MGYG000002756_00379;MGYG000002596_01649;MGYG000003215_00849;MGYG000004055_01475;MGYG000003500_00156;MGYG000004735_02050;MGYG000001141_01291;MGYG000002212_00566;MGYG000000164_02739;MGYG000003786_01019;MGYG000000204_02185;MGYG000001374_01171;MGYG000001689_04166;MGYG000002141_01720;MGYG000003486_01280;MGYG000001793_01089;MGYG000000078_01647;MGYG000004558_00350;MGYG000000278_00938;MGYG000002835_01005;MGYG000003442_01319;MGYG000004359_01015;MGYG000000139_02422;MGYG000001619_00808;MGYG000001493_03358;MGYG000000080_02280;MGYG000000028_01597;MGYG000004879_02709 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,25QPE@186804|Peptostreptococcaceae 0.27586206896551724 186801|Clostridia 1.0 J 0.7241379310344828 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.41379310344827586 rpsK 0.41379310344827586 - 1.0 - 1.0 ko:K02948 0.41379310344827586 ko03010,map03010 0.7241379310344828 M00178,M00179 0.7241379310344828 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.7241379310344828 - 1.0 - 1.0 - 0.7241379310344828 Ribosomal_S11 0.41379310344827586 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01864 0.034482758620689655 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.7241379310344828 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 0.41379310344827586 none 1.0 4069346 2457384 1650380 2196060 3391687 3551724 1558438 2623620 1893749 2266182 1750127 2048658 3565003 3416609 2945958 3535181 2284424 4438005 2727002 5581161 1959794 3680137 2517227 1225699 2743056 2126992 1999330 2468626 2036769 1985979 1004748 2120985 1100898 2956965 3262405 1857148 2963234 1961788 3698297 3383059 2493098 2578936 1723641 1962485 1820545 1966500 0 1830330 1521235 0 2221628 1754809 1346972 1618762 2581385 1622637 1666026 1907346 1361381 975069 1111212 2282742 1652053 1645278 1729926 1790385 3112355 1563784 2226277 1713396 2462981 3511568 3320421 3126611 0 2608668 3182294 5338043 0 3476479 1736013 3016591 2157975 3684392 2977536 3156329 2365560 1554375 3007740 3754398 3430152 3867487 4396068 1825437 3496842 3663504 4033649 6388695 2193912 2567641 0 1955456 4061565 2389531 4636448 3257635 1852968 4761040 3620813 4397569 2562761 3018030 3055867 3171803 5012193 2447251 2092294 4780713 2886333 2149086 3094662 5316139 6117103 3534510 2518549 2705216 2063687 5171975 4920458 2930547 4606827 1081497 3949282 5201107 2652130 1808515 426521 1755848 3257898 2558303 6316784 1084182 3050476 4373993 2102006 2235632 2263343 3086901 4660859 3732201 4311567 1960607 6551172 4309827 6462569 6977870 3511055 4743634 6385662 4888240 5491004 6921545 5896950 5978435 2895283 12782311 6867338 4645913 5419098 1535769 5179150 3511406 5756104 5338060 3120666 3504914 6303578 9244698 3923138 2006922 6257218 3718650 5124718 3081511 4453813 6352626 6737630 11833591 5862745 6593820 +AALVMSK MGYG000002517_00198 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000002517_00198 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2116378 0 0 2640052 0 0 0 0 0 0 2788977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALVNER MGYG000002478_03972 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1225@1|root,COG1225@2|Bacteria,4P08Q@976|Bacteroidetes,2FWN9@200643|Bacteroidia,4AKZE@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 Antioxidant, AhpC TSA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AhpC-TSA,DUF4369,Thioredoxin_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_03972 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1628106 0 0 0 0 0 0 0 1613388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4740491 0 0 0 0 1209699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1771092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2924908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2664936 0 0 0 0 2775986 0 0 0 0 0 0 0 0 0 0 +AALVVMSEEK MGYG000000084_00622;MGYG000000245_02019 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,3WHM7@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000084_00622 0.5 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155343 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3428180 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALVVVGDGK MGYG000001300_02197 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3WICZ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body 1.0 rpsE 1.0 - 1.0 - 1.0 ko:K02988 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S5,Ribosomal_S5_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02197 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02988:RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALWAASLR MGYG000003979_00338 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__CAG-272|g__UMGS1225|s__UMGS1225 sp900549725|m__MGYG000003979 1.0 COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,2203Z@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Pseudouridine synthase 1.0 - 1.0 - 1.0 5.4.99.23 1.0 ko:K06180 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03009 1.0 - 1.0 - 1.0 - 1.0 PseudoU_synth_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003979_00338 1.0 23S rRNA pseudouridine(1911/1915/1917) synthase. - Pseudouridine synthase RluD converts uridines at positions 1911, 1915, and 1917 of 23S rRNA to pseudouridines.-!-These nucleotides are located in the functionally important helix- loop 69 of 23S rRNA. uridine(1911/1915/1917) in 23S rRNA = pseudouridine(1911/1915/1917) in 23S rRNA. 1.0 1.0 1.0 1.0 - 1.0 K06180:rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1380202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 243775 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424125 0 0 0 +AALYDR MGYG000003683_00463;MGYG000002469_01094;MGYG000000756_00776;MGYG000001292_01123 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Belongs to the transketolase family 1.0 tkt 1.0 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA,Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_00463 0.25 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4851012 0 0 0 0 2345342 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1009715 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALYDVADAISIVKK MGYG000000242_00769 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,21Z7M@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000242_00769 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 160529 0 0 0 0 83817 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287855 0 0 0 0 401493 0 0 0 0 496365 0 0 0 0 0 0 0 0 0 0 +AALYNK MGYG000000177_00821 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 2DM8R@1|root,32722@2|Bacteria,4P195@976|Bacteroidetes,2FPH0@200643|Bacteroidia,4AV5T@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Mfa_like_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000177_00821 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 983732 0 479177 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 759552 0 832889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250830 0 500057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309740 0 311374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 514379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 536074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AALYYNNWQVAADASK MGYG000000243_02416 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1435@1|root,COG1435@2|Bacteria,4NFWU@976|Bacteroidetes,2FNY3@200643|Bacteroidia,4APFH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02416 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 895392 941863 2454718 1286043 959801 697612 1066629 0 896279 0 0 671360 0 0 521785 599324 0 0 0 0 856749 661486 0 767495 621718 699758 995913 0 0 907203 1967959 0 2915624 798081 0 874788 683736 2577687 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 284461 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 555733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 310163 0 0 474779 376194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 271976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Carbamidomethyl)LAIMNPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Carbamidomethyl)LTIMNPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 122122 0 51438 0 0 0 0 138005 0 0 0 0 0 0 0 0 0 0 247181 0 0 0 0 0 289013 122998 103938 0 0 0 0 0 0 0 0 102727 202158 115191 223490 0 68919 0 0 0 0 80567 83178 0 0 0 0 0 0 0 0 0 78378 0 0 0 0 0 0 181625 202977 0 0 0 0 0 0 0 0 124012 0 74089 410146 0 172153 0 0 0 0 200430 200728 0 0 0 0 0 0 0 0 0 160983 0 0 0 0 0 678220 476395 643026 0 0 0 0 0 146222 0 0 0 181912 0 162247 0 0 0 0 0 0 952626 390268 0 0 0 0 0 0 0 0 0 573779 0 0 0 0 0 614896 335508 396762 0 0 0 0 0 0 0 0 134135 729517 0 302679 0 631170 0 0 0 0 228303 579290 0 0 0 0 0 0 0 0 0 302375 0 0 0 0 0 612300 521314 343143 0 0 0 491856 0 705240 0 0 597885 629361 548246 +AAM(Met->Glu)LTIMNPDDK MGYG000000077_02468;MGYG000002278_01894;MGYG000004740_00274;MGYG000000087_01268;MGYG000001809_02343;MGYG000000255_01557;MGYG000002517_00543;MGYG000000154_01281;MGYG000000262_02235 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae 0.3333333333333333 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.3333333333333333 etfB 1.0 - 0.6666666666666666 - 0.6666666666666666 ko:K03521 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.6666666666666666 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.1111111111111111 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 654147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1255152 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375525 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Met->Xle)AGFADVPGTR MGYG000000179_01101;MGYG000000133_01756;MGYG000000194_02287;MGYG000000242_00749;MGYG000004747_00336;MGYG000001619_02391;MGYG000000255_01003;MGYG000001602_01322;MGYG000000205_02361;MGYG000004087_00427 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,21ZGH@1506553|Lachnoclostridium 0.6 186801|Clostridia 1.0 E 1.0 Threonine synthase 0.6 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_01101 0.1 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 634259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1109038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)AAAEGDYK MGYG000001562_00661;MGYG000000003_00454;MGYG000003279_00196 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001562_00661 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334676 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 476971 0 0 0 0 0 0 0 0 0 0 303667 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)ADVLK MGYG000002494_04522 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria,3XN36@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) 1.0 luxS 1.0 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 1.0 4.4.1.21 1.0 ko:K07173 1.0 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 1.0 M00609 1.0 R01291 1.0 RC00069,RC01929 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 1.0 LuxS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04522 1.0 S-ribosylhomocysteine lyase. S-ribosylhomocysteinase. The 4,5-dihydroxypentan-2,3-dione formed spontaneously cyclizes and combines with borate to form an autoinducer (AI-2) in the bacterial quorum-sensing mechanism, which is used by many bacteria to control gene expression in response to cell density.-!-Formerly EC 3.2.1.148 and EC 3.3.1.3. S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3- dione + L-homocysteine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways|Biosynthesis of amino acids|Quorum sensing|Biofilm formation - Escherichia coli|Biofilm formation - Vibrio cholerae 1.0 K07173:luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 709754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1073203 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211677 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 827749 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1144833 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)AEKTELSKK MGYG000002517_00455 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia 1.0 186801|Clostridia 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hup 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00455 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 138450 0 0 0 0 0 0 41635 89877 0 0 0 0 0 0 0 357132 0 116932 0 0 0 0 0 0 77980 102762 0 0 0 0 0 0 0 0 0 103975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 57259 0 0 0 0 0 0 0 0 0 0 0 0 0 64827 0 0 0 0 0 0 0 0 0 158197 0 244017 0 0 0 0 0 0 463489 467968 0 0 0 78671 0 0 0 177384 0 221928 0 0 0 0 0 458245 529907 331139 0 0 0 0 0 0 0 0 0 448584 0 284392 0 0 0 0 0 0 94363 243798 0 0 0 1321198 0 0 0 256736 0 265640 0 0 0 0 0 489315 392821 554120 0 0 0 0 0 0 0 0 0 892412 0 +AAM(Oxidation)AGEEVK MGYG000002279_01083;MGYG000002992_00602;MGYG000000038_01566 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG0252@1|root,COG5275@1|root,COG0252@2|Bacteria,COG5275@2|Bacteria,1TQ9S@1239|Firmicutes,24A9Y@186801|Clostridia,27WDD@189330|Dorea 1.0 186801|Clostridia 1.0 EJ 1.0 Glycine/sarcosine/betaine reductase component B subunits 1.0 prdA 1.0 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114 1.0 1.21.4.1 1.0 ko:K10793 1.0 ko00330,map00330 1.0 - 1.0 R02825 1.0 RC00790 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_01083 0.3333333333333333 D-proline reductase. - A pyruvoyl- and L-selenocysteine-containing enzyme found in a number of Clostridial species.-!-The pyruvoyl group, located on the PrdA subunit, binds the substrate, while the selenocysteine residue, located on the PrdB subunit, attacks the alpha-C-atom of D-proline, leading to a reductive cleavage of the C-N-bond of the pyrrolidine ring and formation of a selenoether.-!-The selenoether is cleaved by a cysteine residue of PrdB, resulting in a mixed selenide-sulfide bridge, which is restored to its reduced state by another selenocysteine protein, PrdC.-!-5-aminopentanoate is released from PrdA by hydrolysis, regenerating the pyruvoyl moiety.-!-The resulting mixed selenide-sulfide bridge in PrdC is reduced by NADH.-!-Formerly EC 1.4.1.6 and EC 1.4.4.1. 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine = [PrdC protein]-L-selenocysteine/L-cysteine + D-proline. 1.0 1.0 1.0 1.0 Arginine and proline metabolism 1.0 K10793:prdA; D-proline reductase (dithiol) PrdA [EC:1.21.4.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 703716 1084981 949968 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 481823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 232381 0 0 0 0 0 207368 477520 315251 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)AGFADVPGTR MGYG000000179_01101;MGYG000000133_01756;MGYG000000194_02287;MGYG000000242_00749;MGYG000004747_00336;MGYG000001619_02391;MGYG000000255_01003;MGYG000001602_01322;MGYG000000205_02361;MGYG000004087_00427 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,21ZGH@1506553|Lachnoclostridium 0.6 186801|Clostridia 1.0 E 1.0 Threonine synthase 0.6 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_01101 0.1 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 463809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170650 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 840420 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)ATITNHDDLAAVEAALR MGYG000000099_01611 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,26915@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_01611 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit|K22431:carD; caffeyl-CoA reductase-Etf complex subunit CarD [EC:1.3.1.108] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 649740 0 0 802438 0 0 0 788719 0 615979 0 0 0 580110 0 0 0 0 0 0 0 0 0 0 0 603881 0 0 0 890314 0 0 0 0 727168 0 730111 0 0 0 0 0 0 0 0 186993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 212218 0 0 0 0 192731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)AVANM(Oxidation)R MGYG000002478_00968;MGYG000000243_02351 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00968 0.5 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01818:fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409433 0 0 0 0 169136 0 0 0 0 227798 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 61764 0 0 0 0 73137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77278 0 0 0 0 66489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)DTDDKNVR MGYG000002545_02040;MGYG000002223_00474;MGYG000004487_01385;MGYG000000039_01246;MGYG000002143_00092;MGYG000001300_01096;MGYG000002610_00641;MGYG000004791_00484;MGYG000000099_02658;MGYG000000739_01736;MGYG000004482_00415;MGYG000003819_01815;MGYG000003291_01172;MGYG000000022_00767;MGYG000004784_01270;MGYG000004475_00794;MGYG000001255_01028;MGYG000002105_01011;MGYG000002272_02459;MGYG000002926_00921;MGYG000000195_00123;MGYG000002040_01360;MGYG000002057_00134;MGYG000001616_01899;MGYG000004525_02384;MGYG000001225_01335 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.9615384615384616 MGYG000002545_02040 0.038461538461538464 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 86868 99021 0 232708 0 152886 170032 0 104047 0 0 79209 0 0 0 0 0 614644 0 219892 0 256016 222505 157991 0 143095 0 257737 0 0 0 151731 0 0 0 0 50654 0 136840 146198 0 359489 0 78436 321069 0 617320 0 0 266192 0 0 0 0 0 94561 0 259005 0 0 0 171836 0 173418 0 112681 0 0 0 0 0 0 0 0 288724 0 0 264202 0 195973 0 92336 89016 0 46444 0 0 87063 0 0 0 0 0 50997 0 152279 0 99726 64336 0 0 0 0 155954 0 0 0 81388 0 0 0 0 112183 0 133271 113907 0 0 0 211133 234663 0 128498 0 0 182970 0 0 0 0 0 176676 0 135281 0 218100 0 213404 0 128652 0 391791 0 0 0 201570 0 0 0 0 112071 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42327 0 0 0 0 225323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)GNFAAFSAIPGVEVR MGYG000002274_00295;MGYG000002641_00490;MGYG000001300_00512 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_00295 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10200:ngcE; N-acetylglucosamine transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 451438 0 0 0 0 619291 0 0 0 0 764575 0 0 0 0 0 0 0 0 0 299707 0 0 516275 0 0 0 0 0 973919 0 0 0 0 0 0 0 0 2264058 0 0 0 0 2326919 0 0 0 0 2429556 0 0 0 0 0 0 0 732786 0 943407 0 0 237462 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739864 0 0 0 0 953206 0 0 0 0 822841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599217 0 0 0 0 0 0 0 0 0 110015 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385407 0 0 0 0 314484 0 0 0 0 265169 0 0 0 0 0 0 0 97746 0 0 +AAM(Oxidation)GNFASFEAIPGIEVR MGYG000004271_00710;MGYG000000271_01845 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00710 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10200:ngcE; N-acetylglucosamine transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)GNFASFSAIPGVEVR MGYG000000022_00672 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00672 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10200:ngcE; N-acetylglucosamine transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 661963 0 0 0 0 1502502 0 0 0 0 1238305 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)IQNHQIGLSGGTEK MGYG000002438_03064 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22XE6@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 MGYG000002438_03064 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)KEASEGELK MGYG000004468_00660;MGYG000000044_01948;MGYG000001749_01249;MGYG000001783_01519;MGYG000001546_00360;MGYG000001489_03093;MGYG000004006_01717;MGYG000002007_00386;MGYG000004756_01346;MGYG000003202_00946;MGYG000003681_00790;MGYG000001345_01069;MGYG000002438_00285;MGYG000003514_00715;MGYG000000003_00712;MGYG000000196_00479;MGYG000001562_00044;MGYG000004464_00783;MGYG000001661_02632;MGYG000001313_02393;MGYG000002549_00455;MGYG000001415_02219;MGYG000001337_01464;MGYG000002737_00455;MGYG000004536_01441;MGYG000001789_00244;MGYG000000273_02725;MGYG000000053_01377;MGYG000002281_04045;MGYG000000478_01407 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.43333333333333335 976|Bacteroidetes 0.9 G 0.5333333333333333 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.9666666666666667 gap 0.9666666666666667 - 0.9333333333333333 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.03333333333333333 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 486186 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)LAIM(Oxidation)NPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 777805 0 0 0 0 0 0 0 0 0 0 0 644786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258994 0 0 0 0 0 0 0 0 0 0 0 621891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307795 0 0 0 0 0 0 0 0 0 0 0 306241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227986 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)LAIMNPDDK MGYG000004719_02002;MGYG000001637_02230;MGYG000000271_02101;MGYG000001315_01867;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8333333333333334 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004719_02002 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 506370 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)LAIMNPDDKA MGYG000004762_01002 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Catenibacillus|s__Catenibacillus sp900553975|m__MGYG000004762 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,27IAV@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004762_01002 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443685 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1381762 0 0 0 0 1457300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)LAIMNPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 626951 0 0 1443829 894872 0 1067383 0 426123 0 0 1023352 0 0 0 1257259 1299764 249538 0 690565 1313011 473477 0 0 0 640229 0 0 0 1207581 0 0 764800 0 0 674677 1634546 0 0 0 0 0 0 0 0 0 253950 847633 0 0 0 0 0 0 595877 0 0 0 535859 0 0 0 0 0 0 0 951003 1267835 0 0 0 0 0 0 0 0 295006 0 0 0 0 0 0 0 252774 0 0 686781 0 0 0 0 461898 0 0 0 0 0 0 0 0 598082 0 0 0 0 0 0 0 0 0 0 0 0 278884 0 0 0 0 0 0 0 171459 0 0 259706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830921 0 0 0 0 0 0 0 0 182221 370151 188556 571753 0 567820 0 278909 473839 0 0 625692 704640 0 1002489 0 0 0 0 655645 0 0 415225 623651 0 138111 705387 0 514657 668432 275296 0 594943 0 0 551816 0 0 609927 582280 477374 +AAM(Oxidation)LTIM(Oxidation)NPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 991989 840465 480006 1032091 818034 608022 349359 1038769 1027899 1224685 635745 687518 501301 661291 1026803 894632 1440905 0 1249527 844809 916065 1304642 0 483714 979787 761977 867763 0 302980 596481 351439 767226 329639 863623 637041 587927 620419 0 386064 555088 180437 484271 295797 237321 625685 412872 878740 252363 427211 323838 434001 233688 394060 277248 291720 0 420438 511997 314057 90265 0 522148 235940 319169 299485 0 312781 298819 113372 303500 358769 772195 507118 520901 443660 320590 1702782 2384416 408457 2415978 282859 904254 799602 1422127 561067 1470733 698593 1010438 1173498 1047260 1336308 1055026 1033990 0 1296522 1283916 995191 1658553 0 885337 1286698 1692588 1197543 0 359782 834007 452683 1275481 668863 1246239 1457635 562618 920786 399380 2627342 951718 919058 2423707 1451983 1195437 1645143 3164401 2837985 1752927 1004866 1624672 1232276 3339284 3479748 1421480 2345236 0 2587677 2292008 2252807 550068 0 275421 3100513 2604142 2312708 0 881372 2280810 689528 1076810 948538 1774418 2678350 2110223 2990849 657542 1116906 1664296 2206101 331569 1072681 2136556 1574503 1581285 1370096 2310248 1173291 1636132 755429 1780989 2642668 1573722 1729847 0 1672515 887983 1766291 1551440 0 1533972 1600157 1883976 1670069 0 538734 895995 1143561 456105 1807110 1163272 1002695 1428508 1588359 1349153 +AAM(Oxidation)LTIMN(Deamidated)PDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 0 0 0 0 0 0 0 251339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227968 0 143341 0 0 0 0 0 0 237776 363438 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 250027 0 0 0 0 0 0 0 0 0 0 0 116488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410201 0 0 0 0 0 0 996987 1037629 0 0 0 0 1093172 0 0 0 0 0 0 0 0 0 0 0 1540361 0 0 0 0 0 0 0 0 934064 0 858130 0 634558 0 0 0 0 0 0 0 0 0 0 0 0 447976 0 0 0 0 0 0 0 0 0 0 0 1330799 0 0 0 0 0 0 0 0 969996 0 1154511 0 +AAM(Oxidation)LTIMNPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 1000006 1167170 732597 1323129 1185495 1057836 688950 1500490 908040 1840097 870356 1048189 1060647 719945 1407867 1366607 1962686 0 1639877 1298375 1245566 1979563 0 607647 1210126 1060208 1121926 0 0 935411 574271 628218 561596 949047 1116698 710654 738430 507838 606459 348027 483749 704157 796779 415561 1164535 1077450 1457767 851373 587805 446155 430455 929441 841936 343614 738927 0 818726 901762 688209 355773 0 766195 242142 706386 791027 0 0 563944 820701 619559 358947 898656 695034 836974 922558 539715 2287388 4258790 637426 3475480 278815 1371521 937979 2048370 930312 2625944 721008 1902878 1216209 1837968 2041110 1181319 1818264 0 2942278 2104172 1380362 2418554 0 848928 2017950 2012437 2722386 0 0 1419721 450464 1513463 1143994 2256660 2512418 788498 1518251 623504 4089647 1184292 752258 3387160 1687116 1601875 2059820 4105478 3680754 2090802 1353185 2079555 1416431 4363837 4442183 2073264 2480661 0 2657598 3638100 2851919 759553 0 458246 3589552 4517449 2908803 0 0 2940974 1017965 1367291 1195137 2790391 2909511 2493916 4243536 664044 1656180 1963279 3805638 0 1364233 2247008 2201056 1887014 1859553 3281927 4337808 2325156 1135639 5252619 3078871 2158065 2486552 0 2575990 1093735 1897867 1524104 0 2623978 3067408 2089782 2963342 0 0 818639 1997275 1040018 2801993 1987459 1989684 2963768 2434191 2463478 +AAM(Oxidation)PEAGPVILEPIHTLK MGYG000002274_01087;MGYG000001255_02150;MGYG000003899_02100;MGYG000002641_01949;MGYG000002040_00027;MGYG000004679_00212;MGYG000002272_00718;MGYG000002545_01805;MGYG000001300_02656;MGYG000003291_01552 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 translation elongation 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_01087 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 583995 0 0 0 0 223183 0 0 0 0 109882 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 430899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306755 0 0 0 0 2979585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAM(Oxidation)TVSISDMTVPAQK MGYG000004884_01728 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__KLE1615|s__|m__MGYG000004884 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,27IYQ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000004884_01728 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1329859 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMAAAEGDYK MGYG000001562_00661;MGYG000000003_00454;MGYG000003279_00196 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001562_00661 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1977517 2882552 1626126 3259922 1644257 2645485 2024181 997685 2202042 2838798 915156 3594891 1788350 2155586 2598563 1748476 2170883 0 2667099 2524860 2449668 1983510 0 4095920 2251836 2596921 3286528 0 2338909 3619481 1852800 2477449 1849771 819427 1884213 3235139 2475410 1109073 568083 380801 769285 890344 710753 628189 367168 430075 639482 699340 453356 932147 569740 863070 1059605 754989 831668 0 538691 653971 631469 640959 0 613546 798668 856272 868878 0 536243 995497 527382 656789 697645 0 542918 496255 785426 823506 4032286 1460248 3484664 3194319 3832486 1852573 3550080 3000160 4891510 3198874 2045837 2994872 2120007 3630247 3032537 1775839 2154822 0 2931272 3070976 4355047 1590674 0 1894776 2790888 3952036 2919774 0 2670768 3312558 1754451 1384337 2147404 3657782 1739322 5122170 3217304 3317752 732726 733897 1090079 602699 762811 570628 683520 890789 535297 739295 217957 1369391 1308453 788933 968196 614907 698564 0 706079 766506 968969 199577 0 341354 1260239 1708874 942356 0 981691 1137417 1057897 1117079 1124319 1035311 863568 1038003 1018025 684140 421124 287286 0 407210 145925 0 334493 326515 229422 0 144584 198464 0 0 0 253962 311056 0 0 387557 290189 0 0 0 432500 478143 0 0 0 527244 0 0 189629 511198 0 0 237608 0 +AAMADVLK MGYG000002494_04522 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria,3XN36@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) 1.0 luxS 1.0 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 1.0 4.4.1.21 1.0 ko:K07173 1.0 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 1.0 M00609 1.0 R01291 1.0 RC00069,RC01929 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 1.0 LuxS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04522 1.0 S-ribosylhomocysteine lyase. S-ribosylhomocysteinase. The 4,5-dihydroxypentan-2,3-dione formed spontaneously cyclizes and combines with borate to form an autoinducer (AI-2) in the bacterial quorum-sensing mechanism, which is used by many bacteria to control gene expression in response to cell density.-!-Formerly EC 3.2.1.148 and EC 3.3.1.3. S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3- dione + L-homocysteine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways|Biosynthesis of amino acids|Quorum sensing|Biofilm formation - Escherichia coli|Biofilm formation - Vibrio cholerae 1.0 K07173:luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] 1.0 none 1.0 0 629363 304596 0 0 0 410319 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1053093 0 895274 1327950 0 0 0 0 0 0 732641 713064 0 0 0 0 1058068 0 5787904 5281006 0 0 10453981 4107541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8765544 4222337 0 0 0 0 0 0 3593016 0 0 0 0 0 4734774 0 116164 0 0 0 404544 134074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 289605 0 472263 341872 0 0 0 0 0 0 202556 169809 0 0 0 0 206897 0 0 0 0 0 324386 593169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421710 0 321947 577365 0 0 0 0 0 0 228033 331136 0 0 0 0 237699 0 0 0 0 0 946502 956876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 748435 0 754558 858768 0 0 0 0 0 0 0 614145 0 0 0 0 663446 +AAMAEKTELSK MGYG000002517_00455 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia 1.0 186801|Clostridia 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hup 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00455 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158712 0 0 0 0 0 0 0 0 0 68207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167038 0 0 0 0 0 0 0 0 0 125082 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1002606 0 0 0 0 0 0 0 0 0 724290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 889290 0 0 0 0 0 0 0 0 0 673338 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMAEKTELSKK MGYG000002517_00455 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia 1.0 186801|Clostridia 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hup 1.0 - 1.0 - 1.0 ko:K03530 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00455 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta 1.0 none 1.0 939074 232458 276652 0 455157 350092 0 790888 423934 1007053 0 268942 193003 0 802815 0 1478760 0 1009698 211986 0 290355 0 308506 315730 723112 0 0 0 0 0 0 430676 365987 1063709 597513 752794 183588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190136 0 0 0 182008 0 0 593871 497286 423926 0 432321 353840 0 394375 0 192283 0 653301 370991 0 0 0 0 707058 965337 0 0 0 0 0 0 0 371464 477820 503163 1058141 0 1276758 206099 0 0 265945 341197 0 2281759 1401450 276364 0 1154901 493785 0 2431582 0 532181 0 1274798 885743 0 155912 0 0 2837575 2850076 0 0 0 0 0 0 158658 2975118 1866580 1261305 2044803 143278 2849821 953791 1896371 0 1418830 1759528 0 924892 1957321 3585116 0 1649437 4847593 0 3451417 0 1992150 0 2406129 2059866 0 120034 0 1636832 1758469 2586772 0 0 0 0 0 0 2006557 2195951 2870390 2841859 3630690 1747003 +AAMAGEEVK MGYG000002279_01083;MGYG000002992_00602;MGYG000000038_01566 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG0252@1|root,COG5275@1|root,COG0252@2|Bacteria,COG5275@2|Bacteria,1TQ9S@1239|Firmicutes,24A9Y@186801|Clostridia,27WDD@189330|Dorea 1.0 186801|Clostridia 1.0 EJ 1.0 Glycine/sarcosine/betaine reductase component B subunits 1.0 prdA 1.0 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114 1.0 1.21.4.1 1.0 ko:K10793 1.0 ko00330,map00330 1.0 - 1.0 R02825 1.0 RC00790 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_01083 0.3333333333333333 D-proline reductase. - A pyruvoyl- and L-selenocysteine-containing enzyme found in a number of Clostridial species.-!-The pyruvoyl group, located on the PrdA subunit, binds the substrate, while the selenocysteine residue, located on the PrdB subunit, attacks the alpha-C-atom of D-proline, leading to a reductive cleavage of the C-N-bond of the pyrrolidine ring and formation of a selenoether.-!-The selenoether is cleaved by a cysteine residue of PrdB, resulting in a mixed selenide-sulfide bridge, which is restored to its reduced state by another selenocysteine protein, PrdC.-!-5-aminopentanoate is released from PrdA by hydrolysis, regenerating the pyruvoyl moiety.-!-The resulting mixed selenide-sulfide bridge in PrdC is reduced by NADH.-!-Formerly EC 1.4.1.6 and EC 1.4.4.1. 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine = [PrdC protein]-L-selenocysteine/L-cysteine + D-proline. 1.0 1.0 1.0 1.0 Arginine and proline metabolism 1.0 K10793:prdA; D-proline reductase (dithiol) PrdA [EC:1.21.4.1] 1.0 none 1.0 5865523 3846888 3870978 3144485 0 3608046 0 5191157 3494192 4411667 3391788 4266055 5062244 4903513 6933275 513930 270541 0 5917942 5582653 4998430 4235965 0 1933839 6534368 4115928 3902971 0 3827752 2767342 0 2513201 416109 3121972 5514948 3468943 3486017 3340481 2774338 1081891 114908 3908350 0 339796 0 2981252 1040279 1133702 254862 415532 491468 1428009 2300094 0 0 0 2746757 3536516 1597526 0 0 2246508 2468206 2718889 1473815 0 4751343 1712239 0 152788 0 4100301 1997003 3179312 3092118 0 5101567 4923816 2459146 2863699 0 1264405 0 6676889 3173962 5802523 1844233 2866120 4472656 4998333 6592105 4887895 4924328 0 7130213 9401195 4904081 5060543 0 431557 7001804 4928804 5598458 0 4558839 5695721 0 5509588 6124713 6465575 6568653 4064020 3318009 2371978 2561085 2006326 575699 2725951 0 338360 0 3149775 235160 2998153 2419468 2295036 2498629 1702617 2453807 301122 1827057 0 3923235 1479704 2106193 715495 0 2715698 3113059 2591146 1813670 0 548464 2856405 0 2495051 406135 4262400 2901841 2692039 2363289 894588 0 0 0 0 0 0 0 0 0 0 272371 0 0 0 0 0 0 0 355610 907973 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMAGEEVKAAEK MGYG000002279_01083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena_B|m__MGYG000002279 1.0 COG0252@1|root,COG5275@1|root,COG0252@2|Bacteria,COG5275@2|Bacteria,1TQ9S@1239|Firmicutes,24A9Y@186801|Clostridia,27WDD@189330|Dorea 1.0 186801|Clostridia 1.0 EJ 1.0 Glycine/sarcosine/betaine reductase component B subunits 1.0 prdA 1.0 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114 1.0 1.21.4.1 1.0 ko:K10793 1.0 ko00330,map00330 1.0 - 1.0 R02825 1.0 RC00790 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_01083 1.0 D-proline reductase. - A pyruvoyl- and L-selenocysteine-containing enzyme found in a number of Clostridial species.-!-The pyruvoyl group, located on the PrdA subunit, binds the substrate, while the selenocysteine residue, located on the PrdB subunit, attacks the alpha-C-atom of D-proline, leading to a reductive cleavage of the C-N-bond of the pyrrolidine ring and formation of a selenoether.-!-The selenoether is cleaved by a cysteine residue of PrdB, resulting in a mixed selenide-sulfide bridge, which is restored to its reduced state by another selenocysteine protein, PrdC.-!-5-aminopentanoate is released from PrdA by hydrolysis, regenerating the pyruvoyl moiety.-!-The resulting mixed selenide-sulfide bridge in PrdC is reduced by NADH.-!-Formerly EC 1.4.1.6 and EC 1.4.4.1. 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine = [PrdC protein]-L-selenocysteine/L-cysteine + D-proline. 1.0 1.0 1.0 1.0 Arginine and proline metabolism 1.0 K10793:prdA; D-proline reductase (dithiol) PrdA [EC:1.21.4.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMAGEEVKAAEKK MGYG000002279_01083 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena_B|m__MGYG000002279 1.0 COG0252@1|root,COG5275@1|root,COG0252@2|Bacteria,COG5275@2|Bacteria,1TQ9S@1239|Firmicutes,24A9Y@186801|Clostridia,27WDD@189330|Dorea 1.0 186801|Clostridia 1.0 EJ 1.0 Glycine/sarcosine/betaine reductase component B subunits 1.0 prdA 1.0 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0046992,GO:0050002,GO:0050485,GO:0055114 1.0 1.21.4.1 1.0 ko:K10793 1.0 ko00330,map00330 1.0 - 1.0 R02825 1.0 RC00790 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Gly_reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_01083 1.0 D-proline reductase. - A pyruvoyl- and L-selenocysteine-containing enzyme found in a number of Clostridial species.-!-The pyruvoyl group, located on the PrdA subunit, binds the substrate, while the selenocysteine residue, located on the PrdB subunit, attacks the alpha-C-atom of D-proline, leading to a reductive cleavage of the C-N-bond of the pyrrolidine ring and formation of a selenoether.-!-The selenoether is cleaved by a cysteine residue of PrdB, resulting in a mixed selenide-sulfide bridge, which is restored to its reduced state by another selenocysteine protein, PrdC.-!-5-aminopentanoate is released from PrdA by hydrolysis, regenerating the pyruvoyl moiety.-!-The resulting mixed selenide-sulfide bridge in PrdC is reduced by NADH.-!-Formerly EC 1.4.1.6 and EC 1.4.4.1. 5-aminopentanoate + [PrdC protein]-Se-L-selenocysteinyl-S-L-cysteine = [PrdC protein]-L-selenocysteine/L-cysteine + D-proline. 1.0 1.0 1.0 1.0 Arginine and proline metabolism 1.0 K10793:prdA; D-proline reductase (dithiol) PrdA [EC:1.21.4.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMAGFADVPGTK MGYG000004296_00212;MGYG000001338_02004;MGYG000000142_03243 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3XZ3J@572511|Blautia 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 8.87 1.0 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004296_00212 0.3333333333333333 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 264914 971352 0 0 0 0 0 0 0 0 395703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2340154 1229247 929283 0 0 0 0 1191768 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1403809 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1702477 1334462 496135 0 0 0 0 0 0 0 902911 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 959531 0 1573087 0 0 0 0 724092 +AAMAGFADVPGTR MGYG000000179_01101;MGYG000000133_01756;MGYG000000194_02287;MGYG000000242_00749;MGYG000004747_00336;MGYG000001619_02391;MGYG000000255_01003;MGYG000001602_01322;MGYG000000205_02361;MGYG000004087_00427 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,21ZGH@1506553|Lachnoclostridium 0.6 186801|Clostridia 1.0 E 1.0 Threonine synthase 0.6 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_01101 0.1 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 493420 0 0 449495 0 349614 0 0 0 0 309839 0 395973 570157 774016 558084 0 471400 0 0 680828 0 783393 289821 0 633843 384802 502874 604804 0 0 253908 0 0 0 749404 534974 0 0 0 0 442921 0 0 0 0 0 0 258168 0 263581 268902 303161 0 0 646838 0 0 156709 0 302935 0 0 169866 0 512631 288108 0 0 0 0 0 0 0 0 0 517039 0 0 516253 0 264846 0 0 0 0 510271 0 382524 456605 635118 542633 0 0 0 0 620851 547111 282332 0 0 427300 811080 0 553539 0 0 451907 0 0 0 437257 582931 0 0 0 0 226369 0 304095 0 0 0 0 581982 0 461747 381787 1139274 376034 0 0 0 0 0 639362 362416 315187 0 0 429943 2517870 504632 0 0 337333 0 0 0 748573 264150 0 2381391 0 0 3041325 0 1400121 0 0 0 0 1763134 0 1164795 3216639 2534508 1727802 0 358196 0 0 2853434 1357556 619385 2156749 0 2177143 2771721 596041 3258642 0 0 2585137 0 0 0 2767636 1885487 0 +AAMAGFADVPGTR(Arg->Lys) MGYG000000179_01101;MGYG000000133_01756;MGYG000000194_02287;MGYG000000242_00749;MGYG000004747_00336;MGYG000001619_02391;MGYG000000255_01003;MGYG000001602_01322;MGYG000000205_02361;MGYG000004087_00427 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,21ZGH@1506553|Lachnoclostridium 0.6 186801|Clostridia 1.0 E 1.0 Threonine synthase 0.6 thrC 1.0 - 1.0 4.2.3.1 1.0 ko:K01733 1.0 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 1.0 M00018 1.0 R01466,R05086 1.0 RC00017,RC00526 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS16355 1.0 GHMP_kinases_C,GHMP_kinases_N,PALP,Thr_synth_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_01101 0.1 threonine synthase. - Formerly EC 4.2.99.2. H2O + O-phospho-L-homoserine = L-threonine + phosphate. 1.0 1.0 1.0 1.0 Glycine, serine and threonine metabolism|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01733:thrC; threonine synthase [EC:4.2.3.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1673939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMALQTDPR MGYG000000195_01287;MGYG000002040_00215;MGYG000000022_01148;MGYG000001300_00107;MGYG000002641_00333;MGYG000002274_00742 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WGM4@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 1.0 L 0.6666666666666666 that it carries out the mismatch recognition step. This protein has a weak ATPase activity 0.6666666666666666 mutS 0.6666666666666666 - 1.0 - 1.0 ko:K03555 0.6666666666666666 ko03430,map03430 0.6666666666666666 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03400 0.6666666666666666 - 1.0 - 1.0 - 1.0 MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000195_01287 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Mismatch repair 0.6666666666666666 K03555:mutS; DNA mismatch repair protein MutS 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2166394 1374683 0 0 0 3694258 0 0 0 0 2631293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1538194 1544691 0 0 0 2206738 0 1766011 0 0 1916125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5879719 4589330 0 0 0 1538477 0 5014679 0 0 5362054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1091607 5520303 0 0 0 944971 0 8686588 0 0 9840931 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6070611 0 0 0 0 5429699 0 5044965 0 0 4767307 0 0 0 0 0 0 0 0 0 0 +AAMATITNHDDLAAVEAALR MGYG000000099_01611 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,26915@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Electron transfer flavoprotein domain 1.0 - 1.0 - 1.0 1.3.1.108 1.0 ko:K03521,ko:K22431 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_01611 1.0 caffeoyl-CoA reductase. electron-bifurcating caffeoyl-CoA reductase. The enzyme, characterized from the bacterium Acetobacterium woodii, couples the endergonic ferredoxin reduction with NADH as reductant to the exergonic reduction of caffeoyl-CoA with the same reductant.-!-It uses the mechanism of electron bifurcation to overcome the steep energy barrier in ferredoxin reduction.-!-It also reduces 4-coumaroyl-CoA and feruloyl-CoA. hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit|K22431:carD; caffeyl-CoA reductase-Etf complex subunit CarD [EC:1.3.1.108] 1.0 none 1.0 0 0 190956 409185 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185163 174889 0 0 0 0 3204028 0 1857339 4279766 2534639 1906079 3931689 4366392 2747611 3382833 2314641 2811127 1434992 4486437 6068119 1964367 3465126 0 2614279 4234585 3052858 1848601 0 1847076 2748365 4479765 3873712 0 4322564 3028992 0 3081537 1677683 4042396 3460213 3092602 3351222 1516857 334462 0 339631 0 0 0 503833 365836 224256 420345 264416 0 107998 469085 493395 109877 433448 0 348999 0 0 118538 0 0 324574 0 140326 0 195532 134668 0 413229 0 415965 181774 343480 149978 0 386101 0 192581 0 301773 161282 293732 0 0 103056 181561 0 660912 116921 0 229641 186072 0 0 130309 346771 196735 0 217331 253491 215965 209518 0 227470 177513 0 212688 193226 246867 138628 142125 155387 212319 0 0 0 0 0 0 0 0 0 0 153077 0 313940 0 0 0 423615 0 282003 0 0 0 0 0 119746 0 0 0 0 0 0 0 0 0 114694 0 0 0 +AAMAV(Val->Thr)YSEEGK MGYG000004764_00548 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA2856|s__UBA2856 sp900555005|m__MGYG000004764 1.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate 1.0 dapL 1.0 - 1.0 2.6.1.83 1.0 ko:K10206 1.0 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 1.0 M00527 1.0 R07613 1.0 RC00006,RC01847 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004764_00548 1.0 LL-diaminopimelate aminotransferase. LL-diaminopimelate transaminase. In vivo, the reaction occurs in the opposite direction to that shown above.-!-This is one of the final steps in the lysine biosynthesis pathway of plants (ranging from mosses to flowering plants).-!-Meso-diaminoheptanedioate, an isomer of LL-2,6-diaminoheptanedioate, and the structurally related compounds lysine and ornithine are not substrates.-!-2-oxoglutarate cannot be replaced by oxaloacetate or pyruvate.-!-It is not yet known if the substrate of the biosynthetic reaction is the cyclic or acyclic form of tetrahydropyridine-2,6-dicarboxylate. (2S,6S)-2,6-diaminoheptanedioate + 2-oxoglutarate = (S)-2,3,4,5- tetrahydrodipicolinate + H(+) + H2O + L-glutamate. 1.0 1.0 1.0 1.0 Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Biosynthesis of amino acids 1.0 K10206:E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1273060 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMAVANM(Oxidation)R MGYG000002478_00968;MGYG000000243_02351 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00968 0.5 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01818:fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMAVANMR MGYG000002478_00968;MGYG000000243_02351 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00968 0.5 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01818:fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3] 1.0 none 1.0 2517615 0 3234563 2881092 3228950 2652793 2387559 2111498 3468267 2169404 2271408 2089170 3215227 3546525 3674658 2979103 2336592 2285661 2621148 2461435 2465728 2039882 2557650 2365643 2125208 2237085 2536424 1917562 2184206 2315165 3764827 2689742 3834203 2204865 2916929 2299086 2325451 3505230 1336095 0 1401544 1350374 1414495 1001942 1268960 1386860 1029374 1559723 1030512 969483 1429669 1434909 1366748 1494446 1134443 1618700 1438953 1287352 1203284 1190302 1721241 877849 1260521 1229493 1271520 1584853 1274154 1318969 940219 1001721 1133508 1189938 1510646 1329916 1307291 1201955 1828350 0 1817215 1613804 2254820 1575968 2047292 1400272 1757870 1833162 1394187 1411679 1759619 1490012 1209734 2043247 877683 2269049 1521494 1465505 1162777 1157066 2280087 1705342 1685436 1455811 1456578 1803294 1751316 1327906 1564667 1345419 1205148 1002280 1768716 1918576 1536825 1748959 1514072 0 1570690 1708353 1186755 1513378 538185 1451194 1651536 1521164 1169073 962843 0 1207200 1541851 955735 1147046 1769243 1223951 1218831 824823 929245 559918 972890 2043695 928401 816548 1020535 1524155 0 177887 1598110 1468167 1475610 1355907 770753 1481061 1538536 2376061 0 1565918 1719044 2203044 2232907 2504104 2345783 1978424 1473658 1742602 1751060 2108663 1655370 1737213 2813214 1936787 3581950 2687815 2484629 1446022 2047422 3253281 1470601 1805932 2995847 1916628 2989297 2366974 2156261 1779839 1998144 1694132 2144605 1994583 2313026 1887071 1836567 +AAMDAAHGIEYSTVVTTMAR MGYG000002506_04541 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG1304@1|root,COG1304@2|Bacteria,1QWBP@1224|Proteobacteria,1T2T0@1236|Gammaproteobacteria,3XN3J@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 C 1.0 Protein of unknown function (DUF1116) 1.0 yahG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF1116 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04541 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 1531588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311593 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2424646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1398876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 798987 0 0 0 0 +AAMDDGNEVAK MGYG000000562_00657 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira|s__Lachnospira sp000437735|m__MGYG000000562 1.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,267UV@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction 1.0 ackA 1.0 - 1.0 2.7.2.1 1.0 ko:K00925 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00315,R01353 1.0 RC00002,RC00043 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acetate_kinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000562_00657 1.0 acetate kinase. AK. While purified enzyme from Escherichia coli is specific for acetate, others have found that the enzyme can also use propanoate as a substrate, but more slowly.-!-Acetate can be converted into the key metabolic intermediate acetyl- CoA by coupling acetate kinase with EC 2.3.1.8.-!-Both this enzyme and EC 2.7.2.15 play important roles in the production of propanoate. acetate + ATP = acetyl phosphate + ADP. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00925:ackA; acetate kinase [EC:2.7.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288298 0 0 0 0 0 0 0 0 0 136864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 951543 0 0 0 0 756168 0 0 0 0 179997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMDELLDDPVKNYLK MGYG000003166_00812;MGYG000001300_02509;MGYG000003291_01565 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3WGMV@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 K 1.0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth 1.0 sigA 1.0 - 1.0 - 1.0 ko:K03086 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03021 1.0 - 1.0 - 1.0 - 1.0 Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003166_00812 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03086:rpoD; RNA polymerase primary sigma factor 1.0 none 1.0 0 0 567696 0 0 267979 0 0 0 0 0 0 241213 0 0 234187 0 0 0 0 0 222396 0 258419 0 0 0 0 0 0 0 0 477547 376708 0 0 0 450308 0 0 403691 0 0 571375 0 0 0 0 0 0 437037 0 0 296339 0 0 0 0 0 280960 0 281353 0 0 0 0 0 0 0 0 536981 409687 0 0 0 329806 0 0 0 0 0 221411 0 0 0 0 0 0 161860 0 0 140866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 144322 0 0 0 0 0 0 551369 0 0 553273 0 0 0 0 0 0 553987 0 0 440720 0 0 0 0 0 535530 0 430629 0 0 0 0 0 0 0 0 373751 569024 0 0 0 348144 0 0 0 0 0 52272 0 0 0 0 0 0 76644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54236 0 0 0 0 +AAMDIADKGK MGYG000003937_00998 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 2ET0Z@1|root,33KJ7@2|Bacteria,1VNW5@1239|Firmicutes,254DV@186801|Clostridia,3WQEJ@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zf-ribbon_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_00998 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 779665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 881781 0 0 0 0 418855 0 0 496171 0 840939 0 0 0 0 0 0 0 0 584261 0 607890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 119928 0 0 0 0 222517 0 0 350126 0 92499 0 0 0 0 0 0 0 0 166014 0 286766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 940889 0 0 0 0 0 0 0 391394 0 621090 0 0 0 0 0 0 0 0 105414 0 283302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241556 0 0 0 0 49701 0 0 47281 0 244556 0 0 0 0 0 0 0 0 100171 0 165856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125437 0 0 0 0 107027 0 0 198584 0 272053 0 0 0 0 0 0 0 0 419491 0 +AAMDKIEK MGYG000002438_03132 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0468@1|root,COG0468@2|Bacteria,4NEXT@976|Bacteroidetes,2FN5D@200643|Bacteroidia,22WEY@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 L 1.0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage 1.0 recA 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 - 1.0 ko:K03553 1.0 ko03440,map03440 1.0 M00729 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03400 1.0 - 1.0 - 1.0 - 1.0 RecA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03132 1.0 - - - - 1.0 1.0 1.0 1.0 Homologous recombination 1.0 K03553:recA; recombination protein RecA 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314628 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1135403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMDSGVAR MGYG000000243_02147 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,2FM2T@200643|Bacteroidia,4AKYC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 maeB 1.0 - 1.0 1.1.1.38,1.1.1.40 1.0 ko:K00027,ko:K00029 1.0 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 1.0 M00169,M00172 1.0 R00214,R00216 1.0 RC00105 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,PTA_PTB,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02147 1.0 malate dehydrogenase (oxaloacetate-decarboxylating). | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. | The enzyme catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate, cf. EC 1.1.1.38 and EC 1.1.1.39. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. | (1) (S)-malate + NADP(+) = CO2 + NADPH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Two-component system 1.0 K00027:ME2, sfcA, maeA; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]|K00029:maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1981767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3077179 0 0 0 0 2878083 0 0 371347 0 0 0 0 0 0 0 0 0 1147970 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 714545 0 0 0 0 513280 0 0 396818 0 0 0 0 0 0 0 0 0 811048 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 448323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416498 0 0 0 0 0 0 0 0 0 1133772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 437576 0 0 0 0 815667 +AAMDSGVARK MGYG000000243_02147 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,2FM2T@200643|Bacteroidia,4AKYC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 maeB 1.0 - 1.0 1.1.1.38,1.1.1.40 1.0 ko:K00027,ko:K00029 1.0 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 1.0 M00169,M00172 1.0 R00214,R00216 1.0 RC00105 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,PTA_PTB,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02147 1.0 malate dehydrogenase (oxaloacetate-decarboxylating). | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. | The enzyme catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate, cf. EC 1.1.1.38 and EC 1.1.1.39. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. | (1) (S)-malate + NADP(+) = CO2 + NADPH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Two-component system 1.0 K00027:ME2, sfcA, maeA; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]|K00029:maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] 1.0 none 1.0 0 0 856202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 249450 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMDTDDKNVR MGYG000002545_02040;MGYG000002223_00474;MGYG000004487_01385;MGYG000000039_01246;MGYG000002143_00092;MGYG000001300_01096;MGYG000002610_00641;MGYG000004791_00484;MGYG000000099_02658;MGYG000000739_01736;MGYG000004482_00415;MGYG000003819_01815;MGYG000003291_01172;MGYG000000022_00767;MGYG000004784_01270;MGYG000004475_00794;MGYG000001255_01028;MGYG000002105_01011;MGYG000002272_02459;MGYG000002926_00921;MGYG000000195_00123;MGYG000002040_01360;MGYG000002057_00134;MGYG000001616_01899;MGYG000004525_02384;MGYG000001225_01335 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales 1.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 J 1.0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction 1.0 pnp 1.0 - 1.0 2.7.7.8 1.0 ko:K00962 1.0 ko00230,ko00240,ko03018,map00230,map00240,map03018 1.0 M00394 1.0 R00437,R00438,R00439,R00440 1.0 RC02795 1.0 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 1.0 - 1.0 - 1.0 - 1.0 KH_1,PNPase,RNase_PH,RNase_PH_C,S1 1.0 - 1.0 - 1.0 - 1.0 GH13 0.9615384615384616 MGYG000002545_02040 0.038461538461538464 polyribonucleotide nucleotidyltransferase. polynucleotide phosphorylase. ADP, IDP, GDP, UDP and CDP can act as donors. phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|RNA degradation 1.0 K00962:pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] 1.0 none 1.0 1292686 1128772 1368832 1744484 742934 914269 1701413 1317868 1568291 1112037 1264148 1146126 1190173 1681528 1242419 978727 1115324 1591828 1458704 1462624 1226941 1041039 1564910 1164681 1342774 1286850 1160867 1461743 1173453 1134580 1182295 956879 1099974 1824278 1219383 1272766 1150922 1452439 2056415 1037269 1307558 3191041 1010043 1502234 3489895 1627373 2312505 974124 962059 2335574 1184052 2419837 2128667 1116094 2230380 1227062 2823767 2150230 1325400 963817 1452614 1196510 2416321 2332967 2432207 1235954 144495 1424302 1347128 1235624 1478480 2032678 1285444 2016671 2505020 1674230 774255 615339 604544 1143998 640233 863410 1060058 820338 954068 801988 895554 885268 596688 815085 1022915 665386 808603 707857 1044787 1010784 909881 792924 903496 840534 772215 1058275 824385 1031456 819189 1104943 676698 736279 714091 905647 946472 908604 1223374 822906 1286878 1081495 1749290 1052411 1181263 1376088 1721343 869273 1260625 1394062 896572 1297656 919859 1148812 1067530 1015090 1338971 1041642 1818775 1304116 677941 1459587 377731 1866117 1146604 1096926 1032726 1117647 964065 1419419 1748363 1141175 1477043 1383931 757786 900024 1212364 1730917 365759 194070 307568 219648 305721 233542 511563 465246 396627 299314 0 240766 450874 368987 295129 355245 222127 1064871 273939 318679 210012 286276 1201527 191706 345333 505024 348387 1096747 461822 181072 217873 265798 376591 364695 832987 470607 263480 394326 +AAMDTVTEHR MGYG000002517_01047 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth 1.0 guaB 1.0 - 1.0 1.1.1.205 1.0 ko:K00088 1.0 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 1.0 M00050 1.0 R01130,R08240 1.0 RC00143,RC02207 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 CBS,IMPDH,NMO 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01047 1.0 IMP dehydrogenase. inosinic acid dehydrogenase. The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.-!-Formerly EC 1.2.1.14. H2O + IMP + NAD(+) = H(+) + NADH + XMP. 1.0 1.0 1.0 1.0 Purine metabolism|Drug metabolism - other enzymes|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K00088:IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205] 1.0 none 1.0 0 0 0 0 0 0 0 0 61607 0 0 0 0 0 215244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 800769 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 738054 0 0 0 0 0 712463 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 44524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMDYAAIDNAPEEKER MGYG000001487_02232 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Beduini|s__Beduini massiliensis|m__MGYG000001487 1.0 COG0050@1|root,COG0050@2|Bacteria,2NNQV@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001487_02232 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 620555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3033758 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMEDVLK MGYG000002515_00366;MGYG000002506_02188;MGYG000002323_03171 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG1854@1|root,COG1854@2|Bacteria,1MWQF@1224|Proteobacteria,1RMDZ@1236|Gammaproteobacteria,3XN36@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) 1.0 luxS 1.0 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 1.0 4.4.1.21 1.0 ko:K07173 1.0 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 1.0 M00609 1.0 R01291 1.0 RC00069,RC01929 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECIAI39_1322.ECIAI39_2877,iPC815.YPO3300 1.0 LuxS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002515_00366 0.3333333333333333 S-ribosylhomocysteine lyase. S-ribosylhomocysteinase. The 4,5-dihydroxypentan-2,3-dione formed spontaneously cyclizes and combines with borate to form an autoinducer (AI-2) in the bacterial quorum-sensing mechanism, which is used by many bacteria to control gene expression in response to cell density.-!-Formerly EC 3.2.1.148 and EC 3.3.1.3. S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3- dione + L-homocysteine. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Metabolic pathways|Biosynthesis of amino acids|Quorum sensing|Biofilm formation - Escherichia coli|Biofilm formation - Vibrio cholerae 1.0 K07173:luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21] 1.0 none 1.0 815118 0 658522 707304 0 1850313 923233 951850 758074 1012713 0 0 0 0 806419 0 0 0 499068 654061 816547 1704929 0 2351087 664373 594097 0 0 760705 0 0 0 945887 1113652 870972 816536 554199 1063625 486844 0 343833 318781 0 1019294 286774 430516 250205 553410 0 0 0 0 231681 0 0 0 0 211351 186517 1292679 0 906240 322492 326341 0 0 245654 0 0 0 531956 388450 479658 404858 512283 587716 1225646 0 1741929 812631 0 2763015 1475341 1507839 1403431 1368246 0 0 0 0 1196284 0 0 0 594766 1439183 1538179 1789544 0 2336270 1626460 892249 0 0 1001524 0 0 0 617254 1604322 1442767 1171874 922956 1255519 1052650 0 1325157 821775 0 1434315 1147816 1383933 1261473 1228228 0 0 0 0 1043844 0 0 0 987920 1211008 1035029 1161729 0 1244112 132445 953953 0 0 854271 0 0 0 1369586 1292096 1193740 1422523 969869 1231753 0 0 0 0 0 0 154654 0 0 228813 0 0 0 0 200698 0 0 0 0 134412 0 0 0 74407 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMEEADITPETSVSDTC(Carbamidomethyl)DKMK MGYG000000255_02549 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81|s__CAG-81 sp900066055|m__MGYG000000255 1.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,21XVQ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 E 1.0 Receptor family ligand binding region 1.0 braC 1.0 - 1.0 - 1.0 ko:K01999 1.0 ko02010,ko02024,map02010,map02024 1.0 M00237 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.4 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,Peripla_BP_6,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_02549 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Quorum sensing 1.0 K01999:livK; branched-chain amino acid transport system substrate-binding protein 1.0 none 1.0 352950 0 0 0 0 0 0 326480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 146552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 747525 0 0 0 0 0 0 912888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 644232 0 0 0 0 0 0 0 0 0 0 463523 0 0 0 0 0 0 0 0 317250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 279220 0 +AAMEEANHASR MGYG000001494_01606 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Mesosutterella|s__Mesosutterella massiliensis|m__MGYG000001494 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,3VT2K@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001494_01606 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581910 0 0 0 0 0 0 0 0 0 0 0 0 0 539219 0 0 0 0 0 0 0 0 0 0 821600 0 0 0 0 0 0 0 0 0 0 489134 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMEEGVVVGGGTTYIR MGYG000000215_01245 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella stercorea|m__MGYG000000215 1.0 COG0459@1|root,COG0459@2|Bacteria,4NDZM@976|Bacteroidetes,2FMH4@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 O 1.0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000000215_01245 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMEEHASEAIR MGYG000000164_02794 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG0191@1|root,COG0191@2|Bacteria,1TRS4@1239|Firmicutes,3VSU5@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 H 1.0 Fructose-bisphosphate aldolase class-II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 F_bP_aldolase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_02794 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1058966 0 0 652332 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 79616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMEGMLAPTLK MGYG000000243_02364;MGYG000003681_01846;MGYG000000042_02977;MGYG000002478_00983;MGYG000000224_02076;MGYG000001313_00551;MGYG000001787_00060;MGYG000001346_01637 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,4AKHK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000243_02364 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 890393 0 885424 957940 914249 776279 1154328 601374 745187 721207 725266 0 998528 607253 640883 857681 703745 442952 661660 815104 867764 580835 968205 940395 679272 798128 940719 938441 844609 864938 846515 0 1066897 0 681468 978655 770142 885291 922678 0 979402 1045184 1092889 759344 927979 1141430 484317 829923 905916 0 1598448 1339593 1048011 1508914 772350 802776 1005071 772597 984249 755479 1130114 730058 956817 1018222 1006917 902696 682914 821487 538374 0 815666 0 936619 849006 928686 931154 708914 0 580719 681066 1091284 1010959 1365106 480233 916642 281993 1076785 0 1048361 782534 914545 838090 804978 1517375 618040 685785 735136 668335 1247028 714613 650632 842139 596886 1243927 804030 730250 849856 0 615130 0 727772 1035771 783938 741431 231477 0 438215 134715 862894 265889 449614 387958 240952 343741 447277 0 485153 313345 523343 424380 929162 1073877 354917 1185320 467405 374350 1243696 449652 429584 251113 302293 439471 251168 857852 316838 0 358446 0 367619 476781 400423 256783 817964 0 534756 477971 1014503 632206 779987 851203 696325 388246 748316 0 1116460 545856 848040 1034475 674653 1558326 790479 831715 588064 596744 1366956 569921 812862 754537 251409 1339312 700344 978385 466498 0 442375 0 695635 720148 694516 542590 +AAMEHGLK MGYG000002156_01377;MGYG000004475_01165;MGYG000002926_00510;MGYG000002720_00255;MGYG000001733_00006;MGYG000002794_00566;MGYG000002882_01857;MGYG000004487_00995;MGYG000000089_01469;MGYG000003494_00371;MGYG000004769_00463;MGYG000004779_01663 domain d__Bacteria 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,2N77W@216572|Oscillospiraceae 0.6666666666666666 186801|Clostridia 0.9166666666666666 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002156_01377 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 1.0 none 1.0 1313872 0 981731 0 510854 1426308 1826714 1029285 0 1308196 972881 811578 0 0 0 0 1732244 1557639 0 0 0 1384854 1432843 1128301 0 1448747 0 1915307 0 794070 0 1288744 1400437 0 1144438 1397666 1777636 1004284 1197549 0 1324421 0 1444679 1271364 1357701 1878494 0 1175697 1636565 1100788 0 0 0 0 1026617 0 0 0 0 1080714 0 1103873 0 1476008 0 0 0 939401 0 1464163 916951 0 1341393 1848654 1135425 685357 321119 0 1530485 0 484775 966669 515951 1169485 0 661925 1102575 660128 0 0 0 0 851905 0 0 0 0 1691169 0 676925 0 822527 0 0 0 360804 0 858010 936874 0 1308019 1392701 1071933 1157352 1479759 0 1116420 0 1113885 1259604 1658840 1720023 0 1100354 1076818 1755135 0 0 0 0 1575803 938685 0 0 0 1230700 146593 1391590 0 1945417 0 751517 0 1105358 0 1637465 794298 0 1436638 560004 1356261 1354762 0 0 387089 0 0 0 473768 326126 0 498319 426721 0 0 0 0 0 328040 0 0 0 0 480680 0 847371 0 612483 0 0 0 338322 0 476718 571117 0 1101797 0 1052950 796701 +AAMESGVAR MGYG000002293_01153;MGYG000002478_00270;MGYG000002455_00092;MGYG000003922_01120;MGYG000001346_00985;MGYG000003697_02058 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0280@1|root,COG0281@1|root,COG0280@2|Bacteria,COG0281@2|Bacteria,4NFUJ@976|Bacteroidetes,2FM2T@200643|Bacteroidia,4AKYC@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 maeB 1.0 - 1.0 1.1.1.38,1.1.1.40 1.0 ko:K00027,ko:K00029 1.0 ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020 1.0 M00169,M00172 1.0 R00214,R00216 1.0 RC00105 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Malic_M,PTA_PTB,malic 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01153 0.16666666666666666 malate dehydrogenase (oxaloacetate-decarboxylating). | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)). pyruvic-malic carboxylase. Unlike EC 1.1.1.39, this enzyme can also decarboxylate oxaloacetate, cf. EC 1.1.1.40. | The enzyme catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate, cf. EC 1.1.1.38 and EC 1.1.1.39. (1) (S)-malate + NAD(+) = CO2 + NADH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. | (1) (S)-malate + NADP(+) = CO2 + NADPH + pyruvate. (2) H(+) + oxaloacetate = CO2 + pyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Two-component system 1.0 K00027:ME2, sfcA, maeA; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]|K00029:maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 3371764 0 0 0 0 2810567 0 0 0 0 2617444 0 0 0 0 1870695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4062542 0 0 0 0 2236616 0 0 0 0 3811578 0 0 0 0 2751801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1815268 0 0 0 0 3124059 0 0 0 0 2575766 0 0 0 0 1803466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2065891 0 0 0 0 2877183 0 0 0 0 3742776 0 0 0 0 4934116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4232225 0 0 0 0 3990118 0 0 0 0 3306761 0 0 0 0 3354733 0 0 0 0 0 0 0 0 0 0 +AAMEYGLK MGYG000003891_01855;MGYG000004201_00250;MGYG000001658_00361 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,268PI@186813|unclassified Clostridiales 0.6666666666666666 186801|Clostridia 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_01855 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 741900 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309815 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMFEER MGYG000001378_04455;MGYG000001313_00778;MGYG000004876_01712 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1940@1|root,COG1940@2|Bacteria,4NFZ1@976|Bacteroidetes,2FNGN@200643|Bacteroidia,4AMRT@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 GK 1.0 Psort location Cytoplasmic, score 9.26 1.0 glk 1.0 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_04455 0.3333333333333333 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Galactose metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Neomycin, kanamycin and gentamicin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00845:glk; glucokinase [EC:2.7.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 396457 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 211891 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMGNFAAFSAIPGVEVR MGYG000002274_00295;MGYG000002641_00490;MGYG000001300_00512 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_00295 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10200:ngcE; N-acetylglucosamine transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3032229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 33881705 0 0 0 0 122582061 0 0 0 0 23595456 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15354422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13593967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMGNFASFEAIPGIEVR MGYG000004271_00710;MGYG000000271_01845 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Carbohydrate ABC transporter 1.0 - 1.0 - 1.0 - 1.0 ko:K10200 1.0 ko02010,map02010 1.0 M00205 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.18 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00710 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10200:ngcE; N-acetylglucosamine transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMIEYAQVIAK MGYG000000045_00137 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG0469@1|root,COG0469@2|Bacteria,2NNKX@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 G 1.0 Belongs to the pyruvate kinase family 1.0 pyk 1.0 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009266,GO:0009408,GO:0009628,GO:0009986,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0022607,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 1.0 2.7.1.40,2.7.7.4 1.0 ko:K00873,ko:K00958 1.0 ko00010,ko00230,ko00261,ko00450,ko00620,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00261,map00450,map00620,map00920,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 1.0 M00001,M00002,M00049,M00050,M00176,M00596 1.0 R00200,R00430,R00529,R01138,R01858,R02320,R04929 1.0 RC00002,RC00015,RC02809,RC02889 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iECO103_1326.ECO103_1819,iPC815.YPO2393 1.0 ATP-sulfurylase,PEP-utilizers,PK,PK_C,PUA_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000045_00137 1.0 pyruvate kinase. | sulfate adenylyltransferase. phosphoenol transphosphorylase. | sulfurylase. UTP, GTP, CTP, ITP and dATP can also act as donors.-!-Also phosphorylates hydroxylamine and fluoride in the presence of CO2. | The human phosphoadenosine-phosphosulfate synthase (PAPS) system is a bifunctional enzyme: ATP sulfurylase, which catalyzes the formation of adenosine 5'-phosphosulfate (APS) from ATP and inorganic sulfate and the second step is catalyzed by the APS kinase portion of 3'-phosphoadenosine 5'-phosphosulfate (PAPS) synthase, which involves the formation of PAPS from enzyme bound APS and ATP.-!-This is in contrast to what is found in bacteria, yeasts, fungi and plants, where the formation of PAPS is carried out by two individual polypeptides, EC 2.7.7.4 and EC 2.7.1.25. ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate. | ATP + H(+) + sulfate = adenosine 5'-phosphosulfate + diphosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Purine metabolism|Monobactam biosynthesis|Selenocompound metabolism|Pyruvate metabolism|Sulfur metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|Glucagon signaling pathway|Type II diabetes mellitus|Human papillomavirus infection|Viral carcinogenesis|Central carbon metabolism in cancer 1.0 K00873:PK, pyk; pyruvate kinase [EC:2.7.1.40]|K00958:sat, met3; sulfate adenylyltransferase [EC:2.7.7.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 1179798 0 0 0 0 0 765818 0 0 0 0 413874 0 0 0 0 703105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 575102 0 0 0 0 0 1035586 0 0 0 0 480851 0 0 0 0 669600 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 608948 0 0 0 0 0 473086 0 0 0 0 563464 0 0 0 0 593604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723356 0 0 0 0 0 981938 0 0 0 0 0 0 0 0 0 518038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 307335 0 0 0 0 0 0 0 0 0 293464 0 0 0 0 0 0 0 0 0 0 +AAMIQNHQIGLSGGTEK MGYG000002438_03064 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22XE6@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 GH35 1.0 MGYG000002438_03064 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603066 0 0 788440 0 0 0 0 0 0 362653 0 0 0 0 0 0 0 475764 1141892 0 0 0 0 0 0 0 0 774819 0 796190 0 0 0 0 0 0 0 295611 0 0 200261 0 0 0 0 0 0 371731 0 0 0 0 0 0 0 0 706667 0 0 0 0 0 0 0 0 292457 0 572389 0 0 0 0 0 0 0 1609014 0 0 1778866 0 0 0 0 0 0 1639348 0 0 0 0 0 0 0 1060107 4524556 0 0 0 0 0 0 0 0 4316459 0 2536792 0 0 0 0 0 0 +AAMIQSGQADIVVAGGTENMSSAPYLLR MGYG000002485_00796 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0183@1|root,COG0183@2|Bacteria,378R0@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 I 1.0 Belongs to the thiolase family 1.0 - 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_00796 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 588218 0 0 0 727773 0 0 711147 0 0 1132732 0 0 0 0 0 875284 0 662240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 205118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362521 0 0 0 0 0 0 339756 0 0 443822 0 0 0 0 0 436091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMKEASEGELK MGYG000004468_00660;MGYG000000044_01948;MGYG000001749_01249;MGYG000001783_01519;MGYG000001546_00360;MGYG000001489_03093;MGYG000004006_01717;MGYG000002007_00386;MGYG000004756_01346;MGYG000003202_00946;MGYG000003681_00790;MGYG000001345_01069;MGYG000002438_00285;MGYG000003514_00715;MGYG000000003_00712;MGYG000000196_00479;MGYG000001562_00044;MGYG000004464_00783;MGYG000001661_02632;MGYG000001313_02393;MGYG000002549_00455;MGYG000001415_02219;MGYG000001337_01464;MGYG000002737_00455;MGYG000004536_01441;MGYG000001789_00244;MGYG000000273_02725;MGYG000000053_01377;MGYG000002281_04045;MGYG000000478_01407 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.43333333333333335 976|Bacteroidetes 0.9 G 0.5333333333333333 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.9666666666666667 gap 0.9666666666666667 - 0.9333333333333333 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 0.9666666666666667 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.03333333333333333 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 322449 537570 1080607 297783 1519300 927303 624668 1161476 861588 790027 3488434 1510899 0 0 0 1272572 557044 240458 1082897 563379 531054 946263 530625 506280 950606 753698 208176 427371 0 0 1708482 1656652 691843 684424 694347 0 565931 1000528 125515 235438 297609 213062 366965 154554 194281 321087 0 318955 902624 204288 0 0 0 253936 353897 143704 0 154362 172705 220167 0 0 314545 0 152531 183358 0 0 132688 547456 98642 76652 268025 0 209045 144046 862527 1239291 2293224 506545 1822362 1778995 1058632 1362745 1617581 1356393 3050843 463303 0 0 0 1233805 535960 283421 896590 1073234 496069 679638 241260 852567 1377138 611548 360507 0 0 0 1507714 1101233 991019 1473181 677502 0 1124093 1445836 2325381 2125142 2812891 2015084 3049781 3379530 1651920 3117134 2476128 2969210 4714622 2778099 0 0 0 3696602 2679810 2256942 3229546 1979449 1738515 2455170 2068775 1475336 1741790 2346114 2478540 3384322 0 0 2439625 2328944 3020874 1883275 3150133 0 2569762 2672192 269433 489943 625706 267322 851965 786725 71272 461538 508306 838484 1771452 881079 0 0 0 765537 351183 312292 552808 89285 358178 648573 293713 328785 167319 218757 0 238710 0 0 670312 856365 608641 82906 287629 0 257166 700299 +AAMKPSATLFLAGAAPK MGYG000001365_00415 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium_A|s__Phascolarctobacterium_A succinatutens|m__MGYG000001365 1.0 COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1TSVA@1239|Firmicutes,4H24P@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 - 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001365_00415 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53930 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 77484 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1328705 0 1040018 1147386 0 0 0 0 0 0 966064 0 0 811988 0 1619686 0 0 0 944933 1300001 1016598 0 0 0 1357407 637944 0 1677511 1474845 1315648 0 916125 0 0 1486945 +AAMLAIM(Carbamidomethyl)NPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMLAIM(Oxidation)NPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 422017 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230717 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 451772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMLAIMN(Asn->Met)PDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 112532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 480330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMLAIMN(Deamidated)PDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 786873 0 271956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 360571 0 0 0 0 0 0 188790 0 0 0 313390 270909 0 0 153366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135949 0 0 0 0 0 240963 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 86329 0 0 0 0 217678 93865 0 178137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258693 0 0 0 0 0 0 210508 0 0 0 202690 192606 268534 0 227657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281421 0 0 0 0 0 0 217090 0 0 0 122944 397760 +AAMLAIMNPD(Cation_Ca[II])DKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMLAIMNPD(Cation_Na)DKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMLAIMNPDDK MGYG000004719_02002;MGYG000001637_02230;MGYG000000271_02101;MGYG000001315_01867;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8333333333333334 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8333333333333334 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004719_02002 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 1043448 0 0 1323354 0 0 1149379 686006 812313 0 865846 1122935 0 441727 777863 0 0 0 557204 705243 874043 0 0 0 978531 787213 833769 0 837445 987497 0 0 0 0 0 939778 810094 0 143462 0 0 0 0 0 0 525672 0 0 0 0 0 0 0 0 0 0 0 434305 0 0 0 0 0 381893 285302 0 0 311888 0 0 0 0 0 480525 0 0 156804 0 0 0 0 0 371249 0 0 0 0 0 0 0 0 0 0 0 0 253149 506496 0 0 0 432710 612886 0 0 299635 578328 0 0 0 0 0 498933 398252 0 218385 0 0 346114 0 0 144279 0 124318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 568361 0 0 0 157644 0 0 0 0 0 222940 271403 0 335110 0 0 482634 0 0 605980 406372 419931 0 207822 862246 0 497307 341861 0 0 0 438436 474292 462492 0 0 0 621077 217774 353092 0 248870 670995 0 0 0 0 0 511649 343354 0 +AAMLAIMNPDDKAGLEAALR MGYG000001637_02230;MGYG000004719_02002;MGYG000000271_02101;MGYG000001315_01867;MGYG000000356_02130;MGYG000004762_01002;MGYG000002945_00738 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.8571428571428571 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.8571428571428571 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001637_02230 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 7231453 5265491 5417975 9596422 4907201 5082350 8373336 9243878 8390525 8851104 13210620 12026360 5213789 4977992 6985886 3684463 4893619 1478101 5722996 6723191 8283504 3998123 2021564 2921461 8238967 6470691 8016014 2458994 6394728 13549135 2186050 3166317 3721703 8670158 5596571 7678083 6874062 3637487 2275722 3607046 2151054 2874467 2667343 2469925 3036651 3075375 1587431 1960815 1877863 1559255 3226139 1791503 2191121 1443264 1447201 955685 2155413 3216558 1769971 1234748 906568 3578010 2684323 2434232 2584142 1020600 2806628 2124340 4581322 3611886 2015420 2665614 3261237 2483355 2042955 2532387 3898880 1598961 580759 1522434 735364 754304 2648302 2645715 2076660 1212280 1880238 4016467 3611461 2737029 3360892 2939942 2341381 464932 3128578 3114113 3661739 1095198 293159 675879 3771324 2764208 3669074 663181 2775917 4007166 852178 1571020 1956400 3031000 1621311 2614468 3375420 1082229 517926 420179 914251 282819 395420 314020 353490 440174 482181 251739 477490 1038330 610642 412667 499375 688295 312011 166433 299831 380714 304454 471742 191120 70674 360136 220429 366816 0 160280 258401 526968 364049 912595 190082 443034 273182 275631 625528 2477164 583259 3359028 867915 0 1848565 3437159 1491808 2625019 2137971 1629276 5947413 1415644 3534244 2007963 1271164 3269359 736122 2357883 1898657 2086381 2691383 1121984 1953331 2762191 2862327 1908722 1138005 893380 3096000 923576 0 4131653 8045834 10141129 2867642 12444006 9383444 +AAMLIILK MGYG000001370_03535 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fluxus|m__MGYG000001370 1.0 COG3516@1|root,COG3516@2|Bacteria,4NMKM@976|Bacteroidetes,2FTM9@200643|Bacteroidia,4AQBV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Psort location Cytoplasmic, score 8.96 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 T6SS_VipA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001370_03535 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1551502 0 0 0 0 0 0 +AAMLLR MGYG000001346_01121;MGYG000002478_02896;MGYG000001599_00424;MGYG000000198_02428;MGYG000004797_02907;MGYG000000212_00238;MGYG000000179_00721 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.5714285714285714 976|Bacteroidetes 0.5714285714285714 S 0.5714285714285714 Psort location Cytoplasmic, score 8.96 0.5714285714285714 - 0.5714285714285714 - 1.0 - 0.5714285714285714 - 0.5714285714285714 - 0.5714285714285714 - 0.5714285714285714 - 0.5714285714285714 - 0.5714285714285714 - 0.5714285714285714 - 1.0 - 1.0 - 1.0 GGGtGRT 0.5714285714285714 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_01121 0.14285714285714285 - - - - 0.5714285714285714 0.5714285714285714 0.5714285714285714 0.5714285714285714 - 0.5714285714285714 - 0.5714285714285714 none 1.0 222435 0 0 0 0 0 0 0 0 0 0 0 0 0 201347 0 0 0 0 0 314033 0 0 0 0 222564 185633 0 0 0 0 0 95563 0 0 0 272931 0 86912 0 0 0 0 0 0 0 0 0 106143 0 67811 106136 87794 0 0 0 0 0 0 0 0 0 0 90513 0 0 0 0 0 0 0 0 0 0 74131 83732 1375267 0 1638145 0 0 0 0 0 0 0 1712137 0 1922258 1851867 1693114 0 0 0 0 0 1386516 0 0 0 0 1235494 1111551 0 0 0 1367743 0 847206 0 0 0 1410665 1599990 230733 0 230040 0 0 0 0 0 0 0 97069 0 127967 106631 105871 0 0 0 0 0 117063 0 0 0 0 139241 123868 0 0 0 161517 0 164170 0 0 0 164352 109979 97387 0 80358 0 0 0 0 0 0 0 297955 0 408617 71901 0 0 0 0 0 0 107698 0 0 0 0 1062384 102487 0 0 0 0 0 117719 0 0 0 717669 877041 +AAMLNYQTQTAQAQEAYDNAMK MGYG000000196_05075 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 2AFRI@1|root,315TH@2|Bacteria,4PK03@976|Bacteroidetes,2FTKM@200643|Bacteroidia,4ARI1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_05075 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 453152 659326 0 917235 0 0 0 341714 412602 0 321114 0 0 0 580474 280753 1679577 0 898969 230423 171441 385102 0 491405 0 451269 0 0 0 0 0 0 838401 0 0 0 503093 510883 796656 1314755 0 353228 0 427408 2118989 0 0 286956 471774 1502899 0 0 831483 0 647657 0 0 395579 0 1318589 0 2036905 0 516614 299593 0 0 0 0 791040 1063228 113796 0 0 0 2195369 0 0 0 0 0 0 354759 160104 0 0 0 0 0 0 0 0 0 0 0 0 0 268607 0 575686 0 0 0 0 0 0 0 575418 487009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133078 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2772887 2450634 1882571 2924454 0 1612576 4569251 3581162 3174835 2774258 2189882 3186523 1585098 0 2682193 2260825 3331858 0 1901521 3192837 3716522 2359599 0 1909033 0 2751508 3015145 0 2937801 0 0 2100447 940412 4596070 0 3004083 1845810 1754992 +AAMLSIMNPDDKAGLEAALR MGYG000000997_00555 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900548205|m__MGYG000000997 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 1.0 etfB 1.0 - 1.0 - 1.0 ko:K03521 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000997_00555 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMLT(Thr->Ala)IMNPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 807932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMLTIM(Carbamidomethyl)NPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 330771 226795 194973 0 0 0 0 0 0 0 0 0 0 0 0 0 141079 0 0 0 0 212471 0 87344 0 0 0 0 0 0 82073 0 0 0 0 0 67245 0 167066 44687 120216 0 0 83361 0 0 146282 0 0 0 0 0 0 0 196887 0 0 0 0 0 0 80209 0 175941 0 0 0 0 0 0 0 0 0 76133 0 77913 368693 563713 159271 0 0 105139 0 0 309192 0 0 0 0 0 0 0 191230 0 0 0 0 621761 0 97397 0 464927 0 0 0 0 0 0 194557 0 0 0 339364 0 413125 0 63806 0 0 0 0 0 171047 0 0 0 0 0 0 0 109483 0 0 0 0 0 0 0 0 271300 0 0 0 0 0 0 0 0 0 216445 572417 0 522791 394779 673397 0 0 796438 0 0 990118 0 0 0 0 0 0 0 606890 0 0 0 0 536558 0 595325 0 645940 0 0 0 0 865094 0 783861 0 0 581983 327208 786293 +AAMLTIM(Oxidation)NPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 877578 736033 607539 919335 739701 387883 345639 1105228 596962 1072969 509859 825575 702895 639958 1405635 1450995 1780806 0 1026935 1116946 880455 1927698 0 234973 1143651 844035 738950 0 335988 206121 0 545294 409543 251142 738643 650501 836236 310095 520050 581472 266606 302927 474720 361738 803020 822594 1319071 682777 306256 648705 262949 465239 392033 391046 553367 0 240182 690989 417995 0 0 718722 711224 561919 714089 0 1003107 312009 0 247484 279155 576885 528601 760431 593305 303382 1692164 3474227 266565 2487850 1250621 901113 492538 1546131 536269 1932623 564654 1279622 1131326 1225060 1779234 1321320 1250509 0 1888123 1584955 1235728 1919269 0 739405 1925942 1876777 1715828 0 1059999 1161131 0 1383783 831355 1911983 1929197 594237 1495433 407185 1934831 690431 426440 1577080 1072659 851046 1085442 0 1970087 1376665 731508 1290902 979933 2549260 2569273 1304522 1401464 0 1447124 2423726 2401442 352071 0 220443 2330076 1921078 2018345 0 571918 1960115 0 804859 536793 1407701 1999797 1438617 2315805 240897 2147942 2683274 3978243 503712 2050676 2984572 2440260 1896726 2770541 4596052 4003974 2369610 1656265 5352940 4257500 1988197 3169928 0 2956326 1697060 2057157 2020073 0 3110735 3709450 2370618 3665565 0 1071027 1576094 0 1066845 3303097 2148854 2687520 3139032 3980915 2524199 +AAMLTIMNPD(Cation_Ca[II])DKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 0 96572 0 198278 245715 77562 76595 0 191708 196444 0 0 0 0 161865 90548 108477 0 244635 0 0 330315 0 85161 58114 0 111343 0 0 0 0 0 150226 215350 0 116440 0 120683 0 126998 95462 238603 185435 0 326841 0 63945 306124 0 0 0 0 223130 64472 241731 0 133470 0 0 0 0 103429 216436 0 170574 0 0 0 107731 0 134778 280397 0 248802 0 67519 0 308689 0 581918 0 120661 155132 0 0 542088 0 0 0 0 493458 375140 334657 0 327066 0 0 529435 0 0 449950 0 569991 0 0 0 0 0 68504 477747 0 239646 0 0 0 57645 74481 408901 506932 187580 531623 0 582204 110723 0 0 0 0 672183 288025 491574 0 319595 0 0 93290 0 0 422879 0 789325 0 0 0 0 0 57581 430130 0 296833 0 0 0 719015 1407738 220629 609088 771883 711522 0 644917 1017222 0 0 0 0 1211119 617858 930211 0 760616 0 0 646368 0 400596 802795 0 694519 0 0 0 870203 0 665488 993223 0 643681 0 1136444 +AAMLTIMNPD(Cation_Fe[II])DKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 142132 0 90604 0 0 138936 0 0 88298 323346 0 0 0 0 88701 0 149418 0 136291 0 0 282705 0 57623 0 145438 0 0 0 0 0 0 0 131638 0 0 81093 109035 62742 0 0 0 0 71538 246272 0 56358 198277 0 0 0 0 125745 0 166707 0 89397 0 0 0 0 73183 0 104297 0 0 0 0 0 0 42079 310019 0 0 54519 0 201299 0 0 0 0 92177 75662 0 53134 89509 0 0 0 0 188180 0 102359 0 282538 0 0 250112 0 0 0 134579 0 0 0 0 0 0 99500 166126 0 0 96153 0 531412 0 0 0 0 330467 171421 0 480024 184631 0 0 0 0 511630 0 122523 0 205507 0 0 0 0 0 0 390150 0 0 0 0 0 0 0 196613 0 0 503600 0 520201 0 842921 0 0 530477 507517 0 587162 874993 0 0 0 0 687129 0 806457 0 543846 0 0 0 0 361495 0 383412 0 0 0 0 0 0 569867 809641 0 0 516321 972076 +AAMLTIMNPD(Cation_Mg[II])DKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 195503 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 257692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334521 0 0 0 0 0 0 0 0 0 227267 214901 0 505700 0 0 0 0 0 0 0 0 0 374500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 607197 0 0 0 0 0 0 0 0 0 303276 323163 0 833354 0 0 0 0 0 0 0 0 0 136299 0 0 0 0 0 0 0 0 0 0 0 0 0 0 790493 0 0 0 0 0 0 0 0 0 920966 827743 0 1284024 0 0 0 0 0 0 0 0 0 778410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 793256 0 0 0 0 0 0 0 0 0 1098526 709205 0 +AAMLTIMNPD(Cation_Na)DKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 0 0 276580 472680 0 187837 0 654003 0 0 0 0 0 0 396992 236595 0 0 0 0 436398 160517 0 375838 0 443285 529465 0 0 373108 0 0 0 236673 347179 475131 553598 472370 91444 0 262510 235690 0 0 0 285428 0 0 0 0 0 0 223313 0 0 0 0 0 433493 306021 0 98344 0 649482 375028 0 0 0 0 0 0 577673 509453 174181 474449 0 1053686 0 252155 1144194 0 420009 0 817664 0 0 0 0 0 0 910155 533144 0 0 0 0 807284 872797 0 398260 0 661999 908434 0 0 515539 0 0 417696 1113919 1194700 331032 824295 319016 1242066 0 238483 936109 0 530495 0 1270530 0 0 0 0 0 0 1392687 609204 0 0 0 0 911457 118239 0 0 0 1133556 1139572 0 0 774502 0 0 388668 723095 1033435 1028612 1424608 248736 0 0 0 290710 0 1642603 0 0 0 0 0 0 0 0 2236418 1537570 0 0 0 0 1410287 842714 0 847561 0 1990513 442848 0 0 1288724 0 0 1020682 1707640 323325 0 1114034 1670205 +AAMLTIMNPDD(Cation_Ca[II])KAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64030 0 0 0 0 0 0 0 0 0 0 0 0 68966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254050 0 0 0 0 0 0 0 0 0 0 0 0 326041 0 0 0 0 0 0 0 0 0 0 277111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 760017 0 0 0 0 0 0 592039 0 0 501539 669440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 636061 0 +AAMLTIMNPDD(Cation_Fe[II])KAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 516623 631738 0 0 0 0 0 0 0 0 599755 0 0 0 0 419915 0 0 +AAMLTIMNPDDK MGYG000000077_02468;MGYG000002278_01894;MGYG000004740_00274;MGYG000000087_01268;MGYG000001809_02343;MGYG000000255_01557;MGYG000002517_00543;MGYG000000154_01281;MGYG000000262_02235 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae 0.3333333333333333 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.3333333333333333 etfB 1.0 - 0.6666666666666666 - 0.6666666666666666 ko:K03521 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.6666666666666666 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.1111111111111111 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.6666666666666666 none 1.0 686880 473968 0 673746 489673 350410 0 863139 0 978434 0 0 428272 721290 1453466 319415 390606 0 918711 861562 632619 537274 0 0 1378329 934567 637612 0 333548 0 0 0 277890 0 485769 354055 327571 0 2052662 1397510 1187980 2187137 1130098 1818562 2894083 2060681 1405104 1717317 871457 1611445 1150073 1648675 1593120 1288629 1908579 0 1837798 2721883 2049999 914282 0 1741462 1826173 1747972 2261146 0 2763125 1746041 1243947 1073710 1279226 2502682 1706948 2185588 1571227 1142403 2082086 1045606 657085 2082585 0 733370 1104658 1506978 1034845 1569653 836753 1197705 1181998 1542119 2073662 1124697 1358027 0 2227089 1920210 1652283 2266556 0 702716 1921553 2703917 1976211 0 479912 1640515 396727 1157020 979634 2048529 1895188 1072520 1666974 743558 3404571 1638014 965225 3525982 2284733 1291108 3246873 2873011 3494654 2013984 1501309 1621035 1502587 4929744 3145313 2525657 3315310 0 2674700 3651645 2755888 983629 0 894207 3324031 2733471 3353669 0 1905518 3181850 1168291 1347793 1412017 1513360 2941441 2599708 3527811 925531 3984512 3407159 4156767 513136 1597929 4705483 4584664 4340805 4038250 5154737 2874109 3738028 1180495 5480168 5853747 4618821 4905735 0 5479264 3606143 5280266 3039121 0 3609510 5944982 3785795 5250385 0 1454975 3350171 2952149 1043685 3610638 5634735 3239788 5037103 4338703 3280343 +AAMLTIMNPDDK(Propionamide) MGYG000000077_02468;MGYG000002278_01894;MGYG000004740_00274;MGYG000000087_01268;MGYG000001809_02343;MGYG000000255_01557;MGYG000002517_00543;MGYG000000154_01281;MGYG000000262_02235 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae 0.3333333333333333 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.3333333333333333 etfB 1.0 - 0.6666666666666666 - 0.6666666666666666 ko:K03521 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.6666666666666666 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.1111111111111111 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1546297 0 1595075 0 0 0 0 2253219 0 0 0 0 0 0 0 0 0 0 0 2257335 0 0 0 0 0 0 2118304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMLTIMNPDDKA MGYG000000077_02468;MGYG000002278_01894;MGYG000004740_00274;MGYG000000255_01557;MGYG000002517_00543;MGYG000000154_01281;MGYG000000262_02235 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,25UTI@186806|Eubacteriaceae 0.42857142857142855 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 0.42857142857142855 etfB 1.0 - 0.5714285714285714 - 0.5714285714285714 ko:K03521 0.5714285714285714 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.5714285714285714 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.14285714285714285 - - - - 0.5714285714285714 0.5714285714285714 0.5714285714285714 0.5714285714285714 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.5714285714285714 none 1.0 0 0 0 333296 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 395782 330258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 387562 0 158823 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2479908 0 866811 2056301 0 893258 848147 0 1397873 0 0 1433307 1406192 2211640 0 1183354 955100 0 2259416 2681518 1689139 1583791 0 530884 2733193 2130433 0 0 0 1469872 0 0 944039 0 1636331 1119321 2109533 444237 2328797 0 0 2556249 1124040 627102 1874387 0 2938104 1013418 0 980320 454931 1626567 0 1000040 2405295 0 1165880 2574267 1508851 0 0 0 1435339 1450666 0 0 0 1287442 0 0 719511 0 1582178 2189396 1745914 463395 405239 0 0 0 406457 0 0 0 321492 0 0 845060 0 0 0 313992 448040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMLTIMNPDDKAGLEAALR MGYG000000077_02468;MGYG000000018_00072;MGYG000002278_01894;MGYG000004055_00051;MGYG000004740_00274;MGYG000000087_01268;MGYG000000255_01557;MGYG000001809_02343;MGYG000000154_01281;MGYG000002517_00543;MGYG000000262_02235;MGYG000001319_02234 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia 0.3333333333333333 186801|Clostridia 1.0 C 1.0 electron transfer flavoprotein 0.3333333333333333 etfB 1.0 - 0.75 - 0.75 ko:K03521 0.75 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 0.75 - 1.0 - 1.0 - 1.0 ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_02468 0.08333333333333333 - - - - 0.75 0.75 0.75 0.75 - 1.0 K03521:fixA, etfB; electron transfer flavoprotein beta subunit 0.75 none 1.0 9308575 9170787 8318703 11893453 9947265 7789382 5062534 16385450 8161981 16954929 6778462 11107000 8960861 7413667 11243687 6470418 7639788 1761730 14406241 11431027 11593901 10866563 2956351 4108547 11292737 8685687 10473085 3639458 4721443 8840247 3650239 6304923 4331664 8311170 11293905 7827666 8461722 4968916 9552178 7536478 4075044 13067461 7559503 6897509 14601512 14488261 6069136 10796797 6656181 9033219 6848377 8354740 11348079 5521258 10250376 770510 9620186 15270824 8312924 4907571 0 9613636 10004160 13207561 11179687 384211 15559944 6810047 8127255 6752867 4162696 11269323 9187258 13191439 8798947 3928338 17991533 15935718 3108642 18093442 1071946 8778714 5677344 14542195 5120683 15747104 5385189 13288614 10285077 11601354 16519644 11499343 10508130 65104 21110921 16912638 11164150 20389875 633352 4585202 17990620 15618987 19246030 560237 2683695 11313729 2221672 11116201 8478769 19321232 21144968 5970714 13429626 3889229 28658678 4978339 5062213 21122762 10089963 9253731 11638997 26517507 26260112 9761725 7388188 10235363 8998778 26952807 24455464 12436086 13154661 0 14343646 18913476 18562304 3533624 0 1833595 26606682 23541426 28403939 0 3600132 18294880 3305862 7609344 5443166 15811475 27393708 18476664 29774831 2823441 31402788 30381263 51653745 4832726 18171974 35789090 36015801 23368484 30040511 49078131 40040169 32436970 16292554 57647134 51595920 28316611 47306483 0 38034178 21463349 34992893 29670053 0 32597726 46183232 44783131 43305927 0 10703825 27694132 38756705 16054446 48434612 42199599 24120041 49217675 37988885 43940483 +AAMPEAGPVILEPIHTLK MGYG000002274_01087;MGYG000001255_02150;MGYG000003899_02100;MGYG000002641_01949;MGYG000002040_00027;MGYG000004679_00212;MGYG000002272_00718;MGYG000002545_01805;MGYG000001300_02656;MGYG000003291_01552 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3WGA7@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 translation elongation 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002274_01087 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 576492 700618 802991 906996 272577 487998 404807 527673 688330 0 755083 570459 530608 477745 475970 490343 0 1907987 909355 656432 0 467465 2114624 513302 583206 586104 596335 2209011 0 583326 703942 541288 602272 657451 0 500296 557070 699497 1256111 0 882924 1940542 877008 1318926 1603260 905786 1281621 0 936700 977432 1020599 1671482 1507534 814405 0 2879959 2150613 2077389 0 965145 2735059 1191105 1838416 1743784 1490910 2695285 0 1018039 931072 792218 905762 1169169 0 1331200 1177056 992630 510188 591972 803365 578770 603791 435602 555438 509844 633070 0 668778 708335 556757 466590 440608 460324 0 2404015 738346 301390 0 405790 2374861 571535 542578 647596 472995 2655901 0 623535 489509 577083 431536 491171 0 447321 526546 614175 911381 747669 922481 874523 896668 908838 904982 551711 884810 0 884202 994758 897281 926246 772002 1032568 0 1651580 1146563 985817 0 833764 1728192 716533 910546 737071 675157 1561053 0 862517 862924 188793 987450 725919 0 677828 889403 861211 0 270312 306618 208577 98331 163643 180284 218224 139028 0 218601 182524 188862 100131 123450 184272 0 2762751 90979 0 0 0 3147067 82855 185945 201263 124208 3781739 0 174035 215616 264980 317394 90499 0 323502 101930 292085 +AAMQSDSGLPDVC(Carbamidomethyl)QMYDVGTK MGYG000000031_00361;MGYG000000142_00481;MGYG000000216_00704 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,4H2K7@909932|Negativicutes 1.0 909932|Negativicutes 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000031_00361 0.3333333333333333 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 929494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378344 0 0 0 0 0 0 0 0 0 0 0 0 712150 0 0 0 0 0 0 0 0 990377 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 814569 0 0 0 1251727 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMQTQASSAVDA(Ala->Thr)QAEAIK MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00272 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01421:yhgE; putative membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 866674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMQTQASSAVDAQA(Ala->Thr)EAIK MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00272 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01421:yhgE; putative membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 917421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMQTQASSAVDAQAEA(Ala->Thr)IK MGYG000002517_00272 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Psort location Cellwall, score 1.0 - 1.0 - 1.0 - 1.0 ko:K01421 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00272 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01421:yhgE; putative membrane protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 862725 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429511 0 714510 0 0 0 0 0 870654 0 0 0 0 0 0 0 0 +AAMSEATAPPMK MGYG000004735_00332 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7160|s__UBA7160 sp900757145|m__MGYG000004735 1.0 COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase acetyl-CoA synthase delta subunit 1.0 acsC 1.0 - 1.0 2.1.1.245 1.0 ko:K00197 1.0 ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200 1.0 M00357,M00377,M00422 1.0 R09096,R10219,R10243 1.0 RC00004,RC00113,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhD,FeS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004735_00332 1.0 Co-methyltransferase. - Catalyzes the transfer of a methyl group from the cobamide cofactor of a corrinoid/Fe-S protein to the N5 group of tetrahydrosarcinapterin.-!-Forms, together with EC 1.2.7.4 and EC 2.3.1.169 the acetyl-CoA decarbonylase/synthase complex that catalyzes the demethylation of acetyl-CoA in a reaction that also forms CO2.-!-This reaction is a key step in methanogenesis from acetate. 5,6,7,8-tetrahydrosarcinapterin + methyl-Co(III)-[corrinoid Fe-S protein] = 5-methyltetrahydrosarcinapterin + Co(I)-[corrinoid Fe-S protein] + H(+). 1.0 1.0 1.0 1.0 Methane metabolism|Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00197:cdhE, acsC; acetyl-CoA decarbonylase/synthase, CODH/ACS complex subunit gamma [EC:2.1.1.245] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMSGMLSPELK MGYG000002506_02810;MGYG000002535_00129;MGYG000002494_01785;MGYG000002534_00556 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0532@1|root,COG0532@2|Bacteria,1MV26@1224|Proteobacteria,1RM9X@1236|Gammaproteobacteria,3WXXB@544|Citrobacter 0.75 1236|Gammaproteobacteria 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N,IF2_assoc 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002506_02810 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 0 0 0 0 546587 1057474 0 0 0 0 0 0 0 0 0 0 1113903 0 0 0 0 885254 0 1020231 0 0 0 0 0 0 0 0 0 0 0 0 0 631797 1050385 2126411 0 0 980756 3303064 3095529 0 1194563 0 0 0 0 1563152 0 0 3947199 0 0 0 2271057 4691654 0 1297258 0 1550360 0 0 0 0 0 0 705955 0 0 533986 1242555 0 663639 508083 475468 341518 766681 1173845 498720 0 605023 0 0 0 0 638627 0 0 720766 0 0 0 873358 898775 0 950902 0 369957 0 0 0 0 0 0 594459 0 0 535441 560607 549177 578206 0 0 601747 235083 613109 618204 0 442788 0 0 0 0 534988 0 0 728822 0 0 0 674734 541445 0 454866 0 337706 0 0 0 0 0 0 255409 0 0 704521 498483 322977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMSNELAAGYTLK MGYG000001658_01423 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__SFFH01|s__SFFH01 sp900548125|m__MGYG000001658 1.0 COG1053@1|root,COG3976@1|root,COG1053@2|Bacteria,COG3976@2|Bacteria,1UJBN@1239|Firmicutes,24QYH@186801|Clostridia,26C5N@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,FAD_binding_2,FMN_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001658_01423 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 389706 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 791555 0 0 0 0 1465893 0 0 0 0 1481763 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 606429 0 0 0 0 368457 0 0 0 0 0 0 0 0 0 0 +AAMTDATNEK MGYG000000028_00550;MGYG000002528_02184 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,27PJB@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Ribosomal protein L35 1.0 rpmI 1.0 - 1.0 - 1.0 ko:K02916 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L35p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000028_00550 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02916:RP-L35, MRPL35, rpmI; large subunit ribosomal protein L35 1.0 none 1.0 0 0 0 0 0 140878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336758 0 612022 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 722548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1962239 0 455494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMTVEK MGYG000000179_01986 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 2DKY9@1|root,30VCI@2|Bacteria,1V5YE@1239|Firmicutes,24HJZ@186801|Clostridia,21XSJ@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 zinc-ribbon domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 zinc_ribbon_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_01986 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 478825 0 0 0 0 0 0 0 0 0 0 273610 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 594713 0 0 0 0 0 0 0 0 0 0 785081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 603093 0 0 0 0 0 0 0 0 0 0 1293631 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683588 0 0 0 0 0 0 0 0 0 0 766805 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1918255 0 0 0 0 0 0 0 0 0 0 1301541 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMTVSISDMTEPPEKPQMIK MGYG000002517_00198 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000002517_00198 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 528473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 624778 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMVEAMK MGYG000000233_02257;MGYG000000255_02594 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG0544@1|root,COG2247@1|root,COG5263@1|root,COG0544@2|Bacteria,COG2247@2|Bacteria,COG5263@2|Bacteria,1UYJ9@1239|Firmicutes,248QE@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 S-layer domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Big_2,Big_3_5,CW_binding_1,Cadherin-like,Flg_new,LRR_5,SLH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000233_02257 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 621074 0 0 0 0 0 0 424532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724542 0 0 0 0 0 0 436976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAMVPVVEPSDSAEAK MGYG000000179_00497;MGYG000000198_04624 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,26A1D@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates 1.0 iorA 1.0 - 1.0 1.2.7.8 1.0 ko:K00179 1.0 - 1.0 - 1.0 - 1.0 - 1.0 br01601,ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_00497 0.5 indolepyruvate ferredoxin oxidoreductase. IOR. Preferentially utilizes the transaminated forms of aromatic amino acids and can use phenylpyruvate and 4-hydroxyphenylpyruvate as substrates.-!-This enzyme, which is found in archaea, is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = (indol-3- yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K00179:iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8] 1.0 none 1.0 1219862 0 0 0 0 0 0 0 0 431464 0 0 0 333308 1001652 0 0 0 0 1032066 0 0 0 0 371886 750098 455652 0 635539 0 0 0 0 0 0 748831 0 0 338483 0 0 152260 0 0 0 0 0 389312 0 0 0 0 296013 0 0 0 0 0 0 0 0 0 0 0 428685 0 150968 0 0 0 0 0 0 294928 355645 0 779154 0 0 462505 0 0 0 0 0 411050 0 0 0 815570 758330 0 490061 0 0 698231 0 0 0 0 0 638236 875131 0 919007 0 0 0 0 0 0 524092 518922 0 0 0 0 414865 0 0 0 0 0 463104 0 0 0 362640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 424960 0 0 1141795 0 0 943727 0 0 0 0 0 1171798 0 0 0 1536212 1106028 0 1205713 0 0 1166961 0 0 0 0 843479 1063784 1250186 0 1255275 0 0 0 0 0 0 1198684 1091706 0 +AAMVPVVEPSDSAEAKDFMK MGYG000000179_00497 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,26A1D@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 C 1.0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates 1.0 iorA 1.0 - 1.0 1.2.7.8 1.0 ko:K00179 1.0 - 1.0 - 1.0 - 1.0 - 1.0 br01601,ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_00497 1.0 indolepyruvate ferredoxin oxidoreductase. IOR. Preferentially utilizes the transaminated forms of aromatic amino acids and can use phenylpyruvate and 4-hydroxyphenylpyruvate as substrates.-!-This enzyme, which is found in archaea, is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = (indol-3- yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K00179:iorA; indolepyruvate ferredoxin oxidoreductase, alpha subunit [EC:1.2.7.8] 1.0 none 1.0 375426 0 0 188818 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239775 0 0 0 0 0 0 0 0 332881 248477 0 278523 0 0 235041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 124054 0 0 0 0 0 216026 294525 0 0 0 0 0 0 0 0 177128 0 0 0 0 0 408581 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365955 0 0 387764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 645705 0 0 752606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 482160 0 0 0 0 0 756706 755540 0 0 0 0 0 0 0 0 724806 763738 0 +AAMVTVAK MGYG000002494_04617 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0576@1|root,COG0576@2|Bacteria,1RH8T@1224|Proteobacteria,1S5W5@1236|Gammaproteobacteria,3XM4I@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 O 1.0 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ 1.0 grpE 1.0 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 1.0 - 1.0 ko:K03687 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03029,ko03110 1.0 - 1.0 - 1.0 - 1.0 GrpE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04617 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03687:GRPE; molecular chaperone GrpE 1.0 none 1.0 0 796585 0 0 0 783747 618249 0 0 406324 0 0 0 0 0 0 355492 0 0 0 736840 1130508 0 1383486 230454 0 0 0 334219 434451 0 0 654552 0 0 0 0 492116 0 2367955 2644133 0 1857135 4009820 1919977 0 0 2802449 0 0 0 0 0 0 2418129 0 0 0 2578384 5424885 0 3697192 2252374 0 0 0 3007268 1831026 0 0 2907870 0 0 0 0 2515186 0 0 484296 0 0 374157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428480 0 0 0 0 0 0 0 0 0 0 0 0 0 845165 0 223348 639584 0 216108 656093 761817 0 0 530543 0 0 0 0 0 0 333684 0 0 0 347627 614073 0 281897 686843 0 0 0 175750 589925 0 0 374384 0 0 0 0 163826 0 0 0 0 0 752862 582211 0 0 0 0 0 0 0 0 0 0 0 0 0 429217 705226 0 659513 609385 0 0 0 451492 659714 0 0 0 0 0 0 0 459649 +AAN(Asn->Gly)GVIIITTK MGYG000001787_01504;MGYG000002478_00526;MGYG000000196_04885;MGYG000002438_03064;MGYG000002438_02925;MGYG000003697_01696;MGYG000003697_02942;MGYG000000243_02417;MGYG000000013_00116 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.3333333333333333 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 0.8888888888888888 MGYG000001787_01504 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1013396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Asn->Gly)GVILITTK MGYG000002478_00836;MGYG000004748_01412;MGYG000003693_02459;MGYG000000013_01157;MGYG000002478_02338;MGYG000000196_04885;MGYG000002438_02656;MGYG000004703_01713;MGYG000002549_02801;MGYG000003697_01696;MGYG000003697_02942;MGYG000000105_01953;MGYG000001056_01040;MGYG000004899_00167;MGYG000003681_00932;MGYG000000224_02063;MGYG000001346_01792;MGYG000000174_02248;MGYG000001346_00980;MGYG000000029_03133;MGYG000000029_02281;MGYG000000003_01946;MGYG000003952_01841;MGYG000003693_01019;MGYG000001780_04788;MGYG000001378_04550;MGYG000002478_00526;MGYG000001661_01562;MGYG000000044_02806;MGYG000001661_00232;MGYG000001661_01167;MGYG000001306_00226;MGYG000002560_03505;MGYG000001345_04118;MGYG000003351_02635;MGYG000000196_04852;MGYG000001780_00424;MGYG000003367_00988;MGYG000000236_00670;MGYG000001489_01819;MGYG000000243_02417;MGYG000001783_00138;MGYG000000105_02058;MGYG000000781_02387;MGYG000003362_01220;MGYG000002455_01534;MGYG000002549_04362;MGYG000001789_02404;MGYG000003812_00487;MGYG000002293_00753;MGYG000001789_00624;MGYG000004797_01501;MGYG000002281_03192;MGYG000001489_03122;MGYG000000138_01670;MGYG000000044_02057;MGYG000001787_01504;MGYG000004876_00069;MGYG000002935_01014;MGYG000001345_03656;MGYG000000236_04565;MGYG000002478_02514;MGYG000002614_00404;MGYG000001056_00294;MGYG000004876_02160;MGYG000004006_01269;MGYG000003681_01449;MGYG000001666_00819;MGYG000004899_00413;MGYG000001378_02713;MGYG000001925_02044;MGYG000003493_02393;MGYG000000013_00116;MGYG000001503_01401;MGYG000004797_02606;MGYG000000138_01202;MGYG000001337_00935;MGYG000002438_02925;MGYG000001783_00512;MGYG000000224_00522;MGYG000003701_02338;MGYG000001599_02769;MGYG000000196_01084;MGYG000003681_02804;MGYG000002478_01281;MGYG000000105_01199;MGYG000001346_02872;MGYG000003363_00305;MGYG000001789_01698;MGYG000004899_00346;MGYG000004830_01626;MGYG000002438_03064;MGYG000002834_00630;MGYG000002614_01804;MGYG000004758_01030 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.12631578947368421 976|Bacteroidetes 1.0 P 0.9894736842105263 TonB-linked outer membrane protein, SusC RagA family 0.8315789473684211 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.5157894736842106 - 1.0 - 1.0 - 1.0 - 0.8526315789473684 MGYG000002478_00836 0.010526315789473684 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675899 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2966346 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Asn->Thr)VMEIYGSK MGYG000002272_00822;MGYG000001300_00352;MGYG000002040_00733;MGYG000000022_01091;MGYG000003166_01369;MGYG000002545_02252;MGYG000002641_00365;MGYG000003899_00843 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 0.875 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002272_00822 0.125 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Glyoxylate and dicarboxylate metabolism|Nitrogen metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Biosynthesis of amino acids|Two-component system|Necroptosis|Glutamatergic synapse|GABAergic synapse 1.0 K01915:glnA, GLUL; glutamine synthetase [EC:6.3.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Asn->Tyr)GVIIITTK MGYG000001787_01504;MGYG000002478_00526;MGYG000000196_04885;MGYG000002438_03064;MGYG000002438_02925;MGYG000003697_01696;MGYG000003697_02942;MGYG000000243_02417;MGYG000000013_00116 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.3333333333333333 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 0.8888888888888888 MGYG000001787_01504 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2453599 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Asn->Tyr)GVILITTK MGYG000002478_00836;MGYG000004748_01412;MGYG000003693_02459;MGYG000000013_01157;MGYG000002478_02338;MGYG000000196_04885;MGYG000002438_02656;MGYG000004703_01713;MGYG000002549_02801;MGYG000003697_01696;MGYG000003697_02942;MGYG000000105_01953;MGYG000001056_01040;MGYG000004899_00167;MGYG000003681_00932;MGYG000000224_02063;MGYG000001346_01792;MGYG000000174_02248;MGYG000001346_00980;MGYG000000029_03133;MGYG000000029_02281;MGYG000000003_01946;MGYG000003952_01841;MGYG000003693_01019;MGYG000001780_04788;MGYG000001378_04550;MGYG000002478_00526;MGYG000001661_01562;MGYG000000044_02806;MGYG000001661_00232;MGYG000001661_01167;MGYG000001306_00226;MGYG000002560_03505;MGYG000001345_04118;MGYG000003351_02635;MGYG000000196_04852;MGYG000001780_00424;MGYG000003367_00988;MGYG000000236_00670;MGYG000001489_01819;MGYG000000243_02417;MGYG000001783_00138;MGYG000000105_02058;MGYG000000781_02387;MGYG000003362_01220;MGYG000002455_01534;MGYG000002549_04362;MGYG000001789_02404;MGYG000003812_00487;MGYG000002293_00753;MGYG000001789_00624;MGYG000004797_01501;MGYG000002281_03192;MGYG000001489_03122;MGYG000000138_01670;MGYG000000044_02057;MGYG000001787_01504;MGYG000004876_00069;MGYG000002935_01014;MGYG000001345_03656;MGYG000000236_04565;MGYG000002478_02514;MGYG000002614_00404;MGYG000001056_00294;MGYG000004876_02160;MGYG000004006_01269;MGYG000003681_01449;MGYG000001666_00819;MGYG000004899_00413;MGYG000001378_02713;MGYG000001925_02044;MGYG000003493_02393;MGYG000000013_00116;MGYG000001503_01401;MGYG000004797_02606;MGYG000000138_01202;MGYG000001337_00935;MGYG000002438_02925;MGYG000001783_00512;MGYG000000224_00522;MGYG000003701_02338;MGYG000001599_02769;MGYG000000196_01084;MGYG000003681_02804;MGYG000002478_01281;MGYG000000105_01199;MGYG000001346_02872;MGYG000003363_00305;MGYG000001789_01698;MGYG000004899_00346;MGYG000004830_01626;MGYG000002438_03064;MGYG000002834_00630;MGYG000002614_01804;MGYG000004758_01030 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.12631578947368421 976|Bacteroidetes 1.0 P 0.9894736842105263 TonB-linked outer membrane protein, SusC RagA family 0.8315789473684211 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.5157894736842106 - 1.0 - 1.0 - 1.0 - 0.8526315789473684 MGYG000002478_00836 0.010526315789473684 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2709994 0 0 0 0 0 0 0 0 0 2202198 0 0 0 0 0 0 0 0 0 0 0 2964256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Asn->Xle)ATSLDQYK MGYG000000196_00573 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides thetaiotaomicron|m__MGYG000000196 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_00573 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K01802:E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]|K03770:ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)AGGVATSALEMC(Carbamidomethyl)QNSAR MGYG000000184_00534;MGYG000003455_00764;MGYG000001338_02192 life d__Bacteria 0.6667 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 0.6666666666666666 C 0.6666666666666666 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 - 0.6666666666666666 1.4.1.3,1.4.1.4 0.6666666666666666 ko:K00261,ko:K00262 0.6666666666666666 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6666666666666666 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_00534 0.3333333333333333 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.6666666666666666 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 783760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)AGGVATSALEMSQNSER MGYG000002945_01156;MGYG000000080_02138;MGYG000004689_01489;MGYG000000245_02477;MGYG000000135_03486;MGYG000004839_02530;MGYG000000251_03197;MGYG000000146_00040;MGYG000002212_01108;MGYG000000164_00589;MGYG000000153_01021;MGYG000004296_00383;MGYG000004380_02235;MGYG000000404_01723;MGYG000002517_02750;MGYG000001797_03050;MGYG000000312_01079;MGYG000001637_01313;MGYG000001689_00608;MGYG000000489_02253;MGYG000000280_02447;MGYG000002528_01412;MGYG000003425_04268;MGYG000000076_02271;MGYG000004879_02390;MGYG000000229_01813;MGYG000002670_01100;MGYG000000136_01003;MGYG000002609_02276;MGYG000004719_01514;MGYG000004547_00997;MGYG000003702_00540;MGYG000004055_01618;MGYG000003063_02071;MGYG000000187_02311;MGYG000002279_01299;MGYG000002149_01514;MGYG000002992_01902;MGYG000000271_00907;MGYG000002492_02848;MGYG000002131_02188 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.3170731707317073 186801|Clostridia 0.6829268292682927 C 0.4146341463414634 Belongs to the Glu Leu Phe Val dehydrogenases family 0.4634146341463415 gdhA 0.6829268292682927 - 1.0 1.4.1.3,1.4.1.4 0.6341463414634146 ko:K00261,ko:K00262 0.6341463414634146 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6341463414634146 M00740 0.6829268292682927 R00243,R00248 0.6829268292682927 RC00006,RC02799 0.6829268292682927 ko00000,ko00001,ko00002,ko01000,ko04147 0.6829268292682927 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.6829268292682927 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002945_01156 0.024390243902439025 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6341463414634146 0.6341463414634146 0.6341463414634146 0.6341463414634146 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.6341463414634146 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.6341463414634146 none 1.0 0 0 0 2749364 0 0 0 0 0 730562 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2491403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 269453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 944632 0 0 0 0 0 0 0 782005 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)AGGVATSALEMSQNSMR MGYG000003142_02931;MGYG000000301_02376;MGYG000004022_00658;MGYG000001658_02349;MGYG000000201_03244;MGYG000003427_02564;MGYG000000142_02223;MGYG000002098_00876;MGYG000003012_01963 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.5555555555555556 186801|Clostridia 1.0 C 0.6666666666666666 Belongs to the Glu Leu Phe Val dehydrogenases family 0.7777777777777778 gdhA 0.8888888888888888 - 0.8888888888888888 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003142_02931 0.1111111111111111 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 599756 0 0 0 0 0 0 0 +AAN(Deamidated)DINLK MGYG000004658_01702;MGYG000000074_00133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004658_01702 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399872 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1415012 0 0 0 0 0 0 0 0 0 1865087 0 0 0 0 0 0 0 0 +AAN(Deamidated)DREFAK MGYG000000243_03128;MGYG000002560_00083;MGYG000000042_01472;MGYG000004797_03123;MGYG000001599_00128;MGYG000002478_01519 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03128 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 1386197 0 0 0 0 0 0 0 0 0 853068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1014452 0 0 0 0 777876 0 0 161361 0 0 0 0 0 0 0 0 0 734733 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276550 0 0 0 0 352160 0 0 232969 0 0 0 0 0 0 0 0 0 457740 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 195301 0 0 0 0 177831 0 0 0 0 0 0 0 0 0 0 0 0 48146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 217138 0 0 0 0 232987 +AAN(Deamidated)DREFAKFADSIK MGYG000000243_03128 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03128 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)FEEVC(Carbamidomethyl)LGYNQEEAQAEAQR MGYG000000179_04744 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,21Y4Z@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 glutamate synthase (NADPH), homotetrameric 1.0 gltA 1.0 - 1.0 1.4.1.13,1.4.1.14 1.0 ko:K00266 1.0 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 1.0 - 1.0 R00093,R00114,R00248 1.0 RC00006,RC00010,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,NAD_binding_8,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_04744 1.0 glutamate synthase (NADPH). | glutamate synthase (NADH). NADPH-glutamate synthase. | NADH-glutamate synthase. The reaction takes place in the opposite direction.-!-The protein is composed of two subunits, alpha and beta.-!-The alpha subunit is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.4).-!-The beta subunit transfers electrons from the cosubstrate.-!-The NH3 is channeled through a 31 A channel in the active protein.-!-In the absence of the beta subunit, coupling between the two domains of the alpha subunit is compromised and some ammonium can be produced.-!-In the intact alphabeta complex, ammonia production only takes place as part of the overall reaction.-!-Formerly EC 2.6.1.53. | A flavoprotein (FMN).-!-The reaction takes place in the direction of L-glutamate production.-!-The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2). 2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH. | 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K00266:gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454681 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GNMVVVDK MGYG000001300_02214;MGYG000003899_00615;MGYG000003166_00760 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02214 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GNMVVVDKFAC(Carbamidomethyl)DEYK MGYG000001300_02214;MGYG000001255_02070;MGYG000003899_00615;MGYG000002545_01139;MGYG000002040_00971;MGYG000003166_00760 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02214 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1942816 1660281 0 0 0 1484712 1711382 0 0 1139303 0 1699949 0 1221988 1008251 0 0 0 0 0 0 0 1235841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 814233 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GNMVVVDKFTC(Carbamidomethyl)DEYK MGYG000000022_02039 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_02039 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226493 0 0 0 0 275029 0 0 0 0 154857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449981 0 0 0 0 407206 0 0 0 0 346726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 938534 0 0 0 0 1000471 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GSYYMANK MGYG000000133_00731 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1376@1|root,COG5263@1|root,COG1376@2|Bacteria,COG5263@2|Bacteria,1UVCF@1239|Firmicutes,24BKI@186801|Clostridia,3XZR4@572511|Blautia 1.0 186801|Clostridia 1.0 S 1.0 L,D-transpeptidase catalytic domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,YkuD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00731 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1841712 1030952 1467492 2296785 1646709 2188882 1505968 1334365 604611 1606394 1632709 1380844 857069 1466349 1361513 1291570 1856281 0 1715099 1775905 1202762 1195793 0 1206344 1597907 2623797 1508330 0 1828738 1579995 1711030 2560442 1521813 1869660 1471551 1881565 1993295 1683553 +AAN(Deamidated)GTLFR MGYG000002720_01381 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,2N6ZU@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase 1.0 hpf 1.0 - 1.0 - 1.0 ko:K05808 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 Ribosom_S30AE_C,Ribosomal_S30AE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002720_01381 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K05808:hpf; ribosome hibernation promoting factor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GVASSAFTFQGQK MGYG000001315_00299 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the aldehyde dehydrogenase family 1.0 rocA 1.0 - 1.0 1.2.1.88 1.0 ko:K00294 1.0 ko00250,ko00330,ko01100,map00250,map00330,map01100 1.0 - 1.0 R00245,R00707,R00708,R04444,R04445,R05051 1.0 RC00080,RC00216,RC00242,RC00255 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Pro_dh 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_00299 1.0 L-glutamate gamma-semialdehyde dehydrogenase. pyrroline-5-carboxylate dehydrogenase. This enzyme catalyzes the irreversible oxidation of glutamate-gamma- semialdehyde to glutamate as part of the proline degradation pathway.-!-(S)-1-pyrroline-5-carboxylate, the product of the first enzyme of the pathway (EC 1.5.5.2) is in spontaneous equilibrium with its tautomer L-glutamate gamma-semialdehyde.-!-In many bacterial species, both activities are carried out by a single bifunctional enzyme.-!-The enzyme can also oxidize other 1-pyrrolines, e.g. 3-hydroxy-1- pyrroline-5-carboxylate is converted into 4-hydroxyglutamate and (R)- 1-pyrroline-5-carboxylate is converted into D-glutamate.-!-NADP(+) can also act as acceptor, but with lower activity.-!-Formerly EC 1.5.1.12. H2O + L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + L-glutamate + NADH. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Arginine and proline metabolism|Metabolic pathways 1.0 K00294:E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GVFDDANVQNR MGYG000002506_01355 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG3443@1|root,COG3443@2|Bacteria,1MXFK@1224|Proteobacteria,1RPWU@1236|Gammaproteobacteria,3XN2U@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 May function as a periplasmic zinc chaperone or mediate direct transport of zinc from the periplasm to the cytoplasm under zinc-limited conditions. Binds zinc with high affinity, and can also bind cadmium, mercury or nickel. Preferentially binds Zn(2 ) over Cd(2 ). Contains one high affinity metal binding site, and can bind additional metal ions at other sites 1.0 zinT 1.0 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0007154,GO:0008150,GO:0008270,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0030288,GO:0030313,GO:0031667,GO:0031668,GO:0031669,GO:0031975,GO:0033554,GO:0034224,GO:0042221,GO:0042594,GO:0042597,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0120127 1.0 - 1.0 ko:K09815 1.0 ko02010,map02010 1.0 M00242 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.15.3,3.A.1.15.5 1.0 - 1.0 - 1.0 ZinT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_01355 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K09815:znuA; zinc transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1210605 1513623 872165 0 1083638 2766685 1086598 1790411 1031521 1674999 0 1166010 0 1253273 1280407 0 1042509 0 1320558 0 1096778 2425909 0 1479525 1212945 1345625 1302892 0 1240932 1104209 0 1043376 950442 1508828 1507495 1130621 1263972 715865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GVIIITTK MGYG000001787_01504;MGYG000002478_00526;MGYG000000196_04885;MGYG000002438_03064;MGYG000002438_02925;MGYG000003697_01696;MGYG000003697_02942;MGYG000000243_02417;MGYG000000013_00116 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.3333333333333333 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 0.8888888888888888 MGYG000001787_01504 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1369533 0 0 0 0 0 0 0 337218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1529048 0 0 0 0 0 0 0 898475 0 0 0 0 0 0 0 0 0 0 1152777 0 0 0 0 0 0 0 0 1180879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1253718 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1201358 0 0 0 0 0 0 0 0 0 0 621948 0 0 0 0 0 0 3096480 0 0 0 0 0 0 1518276 0 0 0 +AAN(Deamidated)GVILITTK MGYG000002478_00836;MGYG000004748_01412;MGYG000003693_02459;MGYG000000013_01157;MGYG000002478_02338;MGYG000000196_04885;MGYG000002438_02656;MGYG000004703_01713;MGYG000002549_02801;MGYG000003697_01696;MGYG000003697_02942;MGYG000000105_01953;MGYG000001056_01040;MGYG000004899_00167;MGYG000003681_00932;MGYG000000224_02063;MGYG000001346_01792;MGYG000000174_02248;MGYG000001346_00980;MGYG000000029_03133;MGYG000000029_02281;MGYG000000003_01946;MGYG000003952_01841;MGYG000003693_01019;MGYG000001780_04788;MGYG000001378_04550;MGYG000002478_00526;MGYG000001661_01562;MGYG000000044_02806;MGYG000001661_00232;MGYG000001661_01167;MGYG000001306_00226;MGYG000002560_03505;MGYG000001345_04118;MGYG000003351_02635;MGYG000000196_04852;MGYG000001780_00424;MGYG000003367_00988;MGYG000000236_00670;MGYG000001489_01819;MGYG000000243_02417;MGYG000001783_00138;MGYG000000105_02058;MGYG000000781_02387;MGYG000003362_01220;MGYG000002455_01534;MGYG000002549_04362;MGYG000001789_02404;MGYG000003812_00487;MGYG000002293_00753;MGYG000001789_00624;MGYG000004797_01501;MGYG000002281_03192;MGYG000001489_03122;MGYG000000138_01670;MGYG000000044_02057;MGYG000001787_01504;MGYG000004876_00069;MGYG000002935_01014;MGYG000001345_03656;MGYG000000236_04565;MGYG000002478_02514;MGYG000002614_00404;MGYG000001056_00294;MGYG000004876_02160;MGYG000004006_01269;MGYG000003681_01449;MGYG000001666_00819;MGYG000004899_00413;MGYG000001378_02713;MGYG000001925_02044;MGYG000003493_02393;MGYG000000013_00116;MGYG000001503_01401;MGYG000004797_02606;MGYG000000138_01202;MGYG000001337_00935;MGYG000002438_02925;MGYG000001783_00512;MGYG000000224_00522;MGYG000003701_02338;MGYG000001599_02769;MGYG000000196_01084;MGYG000003681_02804;MGYG000002478_01281;MGYG000000105_01199;MGYG000001346_02872;MGYG000003363_00305;MGYG000001789_01698;MGYG000004899_00346;MGYG000004830_01626;MGYG000002438_03064;MGYG000002834_00630;MGYG000002614_01804;MGYG000004758_01030 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.12631578947368421 976|Bacteroidetes 1.0 P 0.9894736842105263 TonB-linked outer membrane protein, SusC RagA family 0.8315789473684211 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.5157894736842106 - 1.0 - 1.0 - 1.0 - 0.8526315789473684 MGYG000002478_00836 0.010526315789473684 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2083190 2216392 1795882 2002344 1798334 0 1711998 1405688 1851427 1483355 0 2140940 0 1987670 1719727 1918445 1921134 1028382 2352517 1888364 1625789 1566327 1246354 2545887 1520121 2062126 1692389 0 0 1932779 2180210 2888552 2313851 1371229 1997842 1847925 1783184 1598155 2253196 710342 0 1991891 1002803 870360 974747 1271045 1385071 0 990961 1124620 645319 0 1245115 1086559 893282 0 0 936308 0 1052523 2228602 723629 1115058 2011319 1683043 0 861936 801499 694669 1135513 1763260 1050909 1183159 1065822 1169851 0 1170737 1115559 0 973730 1583886 1259393 0 1186657 1312313 1373279 1422645 1648760 0 1142806 1259864 0 774326 942820 1246770 1154604 1082256 1010270 1042584 1129016 1203411 753525 1116288 0 1132360 1365977 1358727 1206452 2042423 970099 1358620 0 1184710 1811657 1959413 2224793 0 1359377 2206935 2353537 1399625 1984348 1999637 1818568 1340004 1904461 1551213 1645425 1908412 1728854 1693919 0 1544855 1299396 3936453 2057176 4526501 1713602 2022839 1898980 0 2365760 1719810 1955490 0 2523757 2260129 2082075 1768497 1873858 2068606 2106544 1158365 1017243 1064952 0 1781680 1927074 0 1628904 1906825 0 1899822 1351142 1630232 869136 1277479 1660528 1284796 0 1351435 1520669 886941 1440948 3164981 1938832 1534617 1314950 1046073 0 1219693 2118833 1311860 1443956 793522 1896539 0 977990 1631825 1246635 +AAN(Deamidated)GVILVTTK MGYG000000243_03100;MGYG000002478_00972;MGYG000004876_00726;MGYG000002478_00682;MGYG000001346_02823 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FW4E@200643|Bacteroidia 0.2 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6 - 1.0 - 1.0 - 1.0 - 0.8 MGYG000000243_03100 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3863861 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4037933 0 0 0 0 0 0 0 835856 0 0 +AAN(Deamidated)GVIMVTTKR MGYG000002438_02926 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,22ZXY@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02926 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 472387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552717 0 0 0 0 0 0 +AAN(Deamidated)GVIVITTK MGYG000004658_01775;MGYG000003152_00999;MGYG000000138_00500;MGYG000000236_03672;MGYG000004763_02090;MGYG000000183_00749;MGYG000004899_00261;MGYG000000183_02215;MGYG000001337_01441;MGYG000000273_01469;MGYG000000215_02004;MGYG000000243_03324;MGYG000001789_02910;MGYG000000168_01320;MGYG000000236_01565;MGYG000001666_00513;MGYG000002561_00966;MGYG000004748_03723;MGYG000001643_01406;MGYG000002478_01932;MGYG000001787_00685;MGYG000004797_01619;MGYG000001552_01556;MGYG000001925_01391;MGYG000004658_01327;MGYG000003374_00894;MGYG000001346_02589;MGYG000001337_01168;MGYG000001489_02092;MGYG000004797_04210;MGYG000001835_00475;MGYG000000183_02645;MGYG000003681_00349;MGYG000004876_03094;MGYG000001337_01171;MGYG000002203_00896;MGYG000002051_00947;MGYG000000168_02423;MGYG000000183_02880;MGYG000002478_02355;MGYG000000074_02074;MGYG000004468_01877;MGYG000004479_02279;MGYG000002933_00766;MGYG000001562_02517 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2G3FU@200643|Bacteroidia,4AV1P@815|Bacteroidaceae 0.2 976|Bacteroidetes 0.9777777777777777 P 0.9111111111111111 TonB-linked outer membrane protein, SusC RagA family 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.4444444444444444 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004658_01775 0.022222222222222223 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 4133527 4070898 7409471 3945906 5235366 3828682 3239598 3212242 3605658 2741025 384202 3225550 6513284 0 3129352 5916113 3587000 1600267 3656242 3538414 3358591 3227051 2652963 4559039 2884603 3564049 0 2549060 4440870 3469333 5689414 5034361 8114028 3768781 3493646 1047167 3507483 8756371 800755 638274 681126 496315 867850 550850 651028 763325 896343 707319 815351 0 1644116 876171 931353 1213350 432238 454505 627775 553382 664769 650973 0 280787 669606 816124 706438 698230 680543 547406 435077 955070 817484 152154 784985 904711 802334 627420 717492 953175 699975 796759 2113429 1901271 1362104 1412228 1714072 1452745 307184 1244419 3648129 0 1176430 2225409 463299 3157848 1582086 1132399 944760 944839 2765111 1575964 1231187 1270475 1049441 0 1314444 1296929 1509411 1249655 936339 940702 1672100 1496814 1306033 901085 1196776 0 299822 726570 0 828386 989501 559610 853558 860348 359697 1115622 1664723 927106 959405 919783 414046 745595 818587 760283 1342328 0 1096649 0 0 1455284 0 0 0 871645 0 440688 0 0 1006866 0 1497761 0 3021699 2283820 2638577 3386757 4383507 4408637 2410742 3224056 3814444 1927519 2040481 0 5544971 1989403 2736049 4763192 2925084 0 3263760 3556742 1472552 3238138 0 2968611 2436415 2459379 2296912 0 3233756 3849026 2608022 3280367 0 2879355 3039909 2123261 3455944 2884206 +AAN(Deamidated)GVIVITTKR MGYG000000243_03324 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03324 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GVIVLTTK MGYG000002478_01932;MGYG000000183_00749;MGYG000004763_02090;MGYG000001337_01168;MGYG000000183_02215;MGYG000001337_01441;MGYG000000183_02645;MGYG000001835_00475;MGYG000000243_03324;MGYG000001789_02910;MGYG000001337_01171;MGYG000000168_02147;MGYG000000168_02423;MGYG000000183_02880;MGYG000000168_01320;MGYG000002561_00966 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2G3FU@200643|Bacteroidia,4AV1P@815|Bacteroidaceae 0.1875 976|Bacteroidetes 0.9375 P 0.875 TonB-linked outer membrane protein, SusC RagA family 0.6875 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.5625 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01932 0.0625 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 3852555 0 0 0 0 0 0 0 1116967 0 1332493 0 0 3499754 0 0 0 0 0 0 0 0 1125116 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1378263 0 0 0 2253009 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1264185 5720343 0 0 0 1353450 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GVIYITTK MGYG000004885_01473;MGYG000003460_00312;MGYG000000243_03196 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,1WDNI@1283313|Alloprevotella 0.6666666666666666 976|Bacteroidetes 1.0 P 1.0 Carboxypeptidase regulatory-like domain 0.6666666666666666 ragA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004885_01473 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316540 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165113 0 0 0 0 0 0 0 0 0 0 701648 0 0 0 0 0 771314 1037584 0 0 0 0 0 0 0 0 0 0 0 0 0 1459731 0 0 0 0 1123484 858688 0 1216980 751976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 390989 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236939 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GVIYITTKR MGYG000000243_03196 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 ragA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03196 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1789265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GVIYVQTK MGYG000001302.1_00590 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 ragA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_00590 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 1227735 1075536 1101502 1352243 0 0 0 0 0 0 0 0 0 0 1384386 2620295 0 0 964585 1574028 1119732 0 0 0 1444051 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463300 0 0 0 0 349315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 896001 1523173 1568443 1106758 0 0 0 0 0 0 0 0 0 0 2634774 1965045 0 0 607501 1865984 1335494 0 0 0 2145082 0 0 0 0 0 0 0 0 0 0 0 0 0 550685 516162 628577 461968 0 0 0 0 0 0 0 0 0 0 1206279 835409 0 0 494277 1604942 419594 0 0 0 330093 0 0 0 0 0 0 0 0 0 0 0 0 0 1639611 1313916 1697457 939915 0 0 0 0 0 0 0 0 0 0 3058099 1284708 0 0 944067 2568673 953251 0 0 0 2344850 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GVLLITTK MGYG000004797_02606;MGYG000001489_00601;MGYG000001489_00865;MGYG000001780_04788;MGYG000000196_04885;MGYG000002438_02925;MGYG000004899_01078;MGYG000000243_02417;MGYG000001783_00138;MGYG000001783_00512;MGYG000001925_01678;MGYG000004899_02902;MGYG000001925_00504;MGYG000001925_02673;MGYG000002834_00630;MGYG000002293_00753;MGYG000004797_01501 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.17647058823529413 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.8823529411764706 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.5294117647058824 - 1.0 - 1.0 - 1.0 - 0.7647058823529411 MGYG000004797_02606 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1402958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4309533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)GVVFVTTK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01126 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 446981 0 465483 0 347373 162087 0 340055 0 500047 0 205533 0 342585 238896 563509 0 0 768921 548036 267687 487155 0 0 707943 507372 0 0 412573 490504 0 437804 352557 0 259173 433719 232348 232567 2425899 0 2036585 2626342 1476830 1179487 0 2723092 3013155 2635610 0 2188330 0 2903122 3474419 1265586 0 0 2363468 2516389 2094819 847772 0 908210 2184279 2976759 2414349 0 1948113 1889431 0 1806559 2390886 0 2420492 2494623 3692424 1913917 288024 0 203772 344018 223124 197323 0 373158 613918 274062 0 145030 0 275869 327774 233394 0 0 163946 493631 0 171136 0 216436 243156 274962 278227 0 279980 219038 0 211518 316629 0 280201 540234 436402 226585 561591 0 547041 402680 401539 242009 0 236291 0 526591 0 378754 0 438049 456237 0 0 0 675159 685850 718196 0 0 286973 513622 632543 866581 0 526208 452070 0 352530 0 0 601445 532401 560543 934233 494164 0 247436 219110 658773 284636 0 234371 470717 426089 0 217864 0 0 409871 274669 0 0 258101 671370 0 245917 0 426428 192949 423757 381097 0 373979 577980 0 560742 136370 0 350958 271239 497948 258387 +AAN(Deamidated)GVVIITTK MGYG000000042_01138;MGYG000002478_01456;MGYG000004876_03105 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4772@1|root,COG4772@2|Bacteria,4PM03@976|Bacteroidetes,2G09Q@200643|Bacteroidia,4AV6D@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01138 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1117822 0 0 0 0 403782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 708280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413209 1177067 241135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 606588 0 0 0 0 0 0 0 0 439704 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683031 0 0 0 0 0 0 0 0 756528 0 0 0 732766 +AAN(Deamidated)GVVLITTK MGYG000002438_02058;MGYG000003697_00063;MGYG000001306_00077;MGYG000002438_00500;MGYG000002478_01456;MGYG000002960_00789;MGYG000002455_02640;MGYG000001780_01166;MGYG000000781_01695;MGYG000004876_02091;MGYG000003697_02396;MGYG000004797_02570;MGYG000001346_03464;MGYG000004899_00028;MGYG000000243_03191;MGYG000000196_00609;MGYG000002834_00176;MGYG000002478_02188;MGYG000004876_01524;MGYG000001643_02196;MGYG000001835_01972;MGYG000002171_01681;MGYG000004876_03105;MGYG000001643_01263 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.20833333333333334 976|Bacteroidetes 1.0 P 0.9166666666666666 TonB-linked outer membrane protein, SusC RagA family 0.7083333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 0.9166666666666666 MGYG000002438_02058 0.041666666666666664 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 2543503 0 0 0 0 0 0 0 0 0 0 0 933239 0 0 0 0 2302869 0 0 0 0 0 0 0 314949 0 0 547227 0 548818 0 0 197987 0 0 0 0 503234 1204314 0 0 0 0 0 0 0 0 714175 565611 2847356 479318 690434 659552 416141 0 0 875871 0 0 683489 541967 0 560978 698331 680886 0 0 0 0 0 819880 0 0 0 0 403176 534614 0 0 0 0 0 388421 0 0 460390 473534 275507 532816 0 544393 673842 257948 0 494839 0 632640 398362 0 0 0 657254 576343 516838 0 2543567 0 0 1260496 0 0 0 0 1182702 669265 0 0 0 0 0 967052 0 0 653702 1333086 929263 649851 1293371 698658 968025 344935 0 359745 0 607911 1835635 2081471 0 1103646 701100 0 776071 0 685008 0 0 1074715 0 0 0 0 477231 2580039 0 0 0 0 0 3100667 0 0 957480 606474 2867282 1147076 0 0 0 2307338 0 1632359 0 1142678 0 332036 0 662170 804370 0 +AAN(Deamidated)GVVMITTK MGYG000002478_01935;MGYG000000781_01691 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01935 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 515566 0 423408 636210 315260 0 0 404874 411436 0 0 284448 394062 691038 530862 0 0 0 0 575726 0 257294 0 0 0 893370 559638 0 0 376075 0 167208 422655 529248 716852 579818 700060 0 1874988 0 2079576 2003624 2579704 1758481 0 2399298 2023867 1981901 0 1819835 3791111 2126093 2311614 2478255 0 0 0 1804066 0 1582073 0 1309042 0 2091487 1926621 0 1828953 1704498 1331463 2153073 2371215 2278266 2565883 2453444 2583111 1822192 640026 0 457787 0 430958 0 0 0 0 0 0 843923 144178 0 267248 0 0 0 0 1924343 0 0 0 355664 0 0 0 0 374612 406200 531739 325337 313665 290866 1241071 462628 1213965 0 505407 0 0 364156 494256 549729 0 370319 585099 535063 0 477163 410715 0 600549 455277 0 0 0 450756 0 317437 0 0 0 583547 334646 0 0 530259 0 0 303719 571200 559648 431244 576681 0 0 0 0 0 963184 980297 0 0 0 450489 0 0 688900 429613 1466097 0 0 0 0 0 0 0 0 673963 0 594107 378837 0 0 486145 0 809566 0 0 638371 491331 0 0 +AAN(Deamidated)GVVMITTKK MGYG000002478_01935 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01935 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1042135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)LDAIHDTVHEM(Oxidation)AR MGYG000000123_00688;MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000002278_00133;MGYG000000139_02333;MGYG000000274_00102;MGYG000000249_00436;MGYG000000245_00992;MGYG000002702_00869;MGYG000004785_01880;MGYG000000076_00982;MGYG000002517_02838;MGYG000001560_01146;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000004263_01270;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000002837_00277;MGYG000000208_01702;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000000909_00619;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000004697_00836;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.45 186801|Clostridia 0.975 C 1.0 Rubrerythrin 0.6 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.975 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000123_00688 0.025 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 906594 0 0 0 0 780027 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1419654 0 721421 0 0 0 0 0 0 0 0 0 0 0 0 1106408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1476817 0 0 0 0 1146260 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1500499 0 0 0 1183798 0 0 0 0 0 0 0 0 0 0 831433 0 919145 0 0 0 0 495714 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394766 0 671890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)LDAIHDTVHEM(Oxidation)ARDEAR MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000000139_02333;MGYG000000249_00436;MGYG000000245_00992;MGYG000000076_00982;MGYG000002517_02838;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.4482758620689655 186801|Clostridia 0.9655172413793104 C 1.0 Rubrerythrin 0.6551724137931034 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.9655172413793104 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001456.1_00549 0.034482758620689655 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)LDAIHDTVHEMAR MGYG000000123_00688;MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000002278_00133;MGYG000000139_02333;MGYG000000274_00102;MGYG000000249_00436;MGYG000000245_00992;MGYG000002702_00869;MGYG000004785_01880;MGYG000000076_00982;MGYG000002517_02838;MGYG000001560_01146;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000004263_01270;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000002837_00277;MGYG000000208_01702;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000000909_00619;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000004697_00836;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.45 186801|Clostridia 0.975 C 1.0 Rubrerythrin 0.6 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.975 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000123_00688 0.025 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 867120 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)LMLDAGAK MGYG000001661_00681;MGYG000001378_00980 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EF 1.0 COG0462 Phosphoribosylpyrophosphate synthetase 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001661_00681 0.5 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00948:PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2604318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)PTPEKPFVLGC(Carbamidomethyl)PTGSSPLGMYK MGYG000002171_00281;MGYG000002455_02070;MGYG000000196_01768;MGYG000001661_00842;MGYG000003351_04413;MGYG000002549_00225;MGYG000002478_04559;MGYG000002560_02540;MGYG000000243_00067;MGYG000001378_02954;MGYG000004876_00832;MGYG000000013_02920;MGYG000000029_00780 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,4AKMP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_00281 0.07692307692307693 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K02564:nagB, GNPDA; glucosamine-6-phosphate deaminase [EC:3.5.99.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 593377 0 891210 0 0 0 0 0 0 0 0 0 0 0 0 0 291598 0 0 0 0 0 0 0 0 0 0 735906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 518887 0 0 0 0 0 0 0 0 0 0 327725 0 0 0 0 0 0 0 0 0 0 436745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 680588 0 0 0 0 0 0 0 0 0 0 589449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 983188 0 1121603 0 0 0 0 0 0 0 0 0 0 0 0 0 229697 0 0 0 0 0 0 0 0 0 0 952272 0 0 +AAN(Deamidated)VALIGYEK MGYG000000198_03138;MGYG000001564_03639 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,2235C@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 CQ 1.0 BMC domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_03138 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 1656526 0 0 0 1436305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1563244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 715771 0 0 0 1144285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)VIAK MGYG000000115_00663 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium_J|s__Clostridium_J sp902363375|m__MGYG000000115 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,36DMF@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000115_00663 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 451918 0 0 0 0 0 0 393451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Deamidated)VTLVGK MGYG000000152_02876 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lacrimispora|s__Lacrimispora sp902363835|m__MGYG000000152 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 1.0 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000152_02876 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2425866 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAN(Methyl+Deamidated[N](Asn->Glu)VALVGTEK MGYG000000142_01601;MGYG000000301_01353;MGYG000000212_01002;MGYG000002312_02491;MGYG000003012_02044;MGYG000003822_02069;MGYG000000002_00289;MGYG000003821_00240;MGYG000000171_01279;MGYG000002772_00614;MGYG000000200_00386;MGYG000000263_00751;MGYG000001338_00128;MGYG000004785_00404;MGYG000000031_02918;MGYG000002186_00350;MGYG000000252_02288;MGYG000004733_01675;MGYG000002298_00401;MGYG000000216_00449 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.95 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.95 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01601 0.05 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3309875 0 0 0 0 0 0 0 0 0 0 0 0 3755964 0 0 0 0 0 0 0 0 0 0 0 2266153 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAAAQVEK MGYG000000074_00307;MGYG000000003_01005;MGYG000004658_02496 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 2E4BG@1|root,32Z73@2|Bacteria,4NUZ9@976|Bacteroidetes 1.0 976|Bacteroidetes 1.0 S 1.0 Histone H1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Hc1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_00307 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 3874137 0 7109174 3638023 0 0 0 0 6615637 0 0 0 5151792 0 0 5115628 0 0 0 0 0 0 0 6859402 0 0 0 6344502 7785010 5317241 0 0 0 5423469 0 0 0 0 4736920 0 7431640 6200006 0 0 0 0 8900065 0 0 0 9264927 0 0 8609186 0 0 0 0 0 0 0 6700238 0 0 0 5496090 7746343 4559307 0 0 0 6123926 0 0 0 0 16881970 0 17355845 16096660 0 0 0 0 21221793 0 0 0 19499572 0 0 14863921 0 0 0 0 0 0 0 18411756 0 0 0 28585019 16340692 21017061 0 0 0 22179205 0 0 0 0 3329350 0 3315920 3109571 0 0 0 0 3309519 0 0 0 4179399 0 0 2974769 0 0 0 0 0 0 0 4172434 0 0 0 3404555 3631999 3239925 0 0 0 3989509 0 0 0 0 1182103 0 1858599 2089316 0 0 0 0 1764969 0 0 0 3045668 0 0 1630051 0 0 0 0 0 0 0 4245227 0 0 0 2306278 2989994 2316146 0 0 0 1684361 0 0 0 +AANAAFAK MGYG000001540_00252 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Mycobacteriales|f__Mycobacteriaceae|g__Corynebacterium|s__Corynebacterium provencense|m__MGYG000001540 1.0 COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,22JTF@1653|Corynebacteriaceae 1.0 201174|Actinobacteria 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000001540_00252 1.0 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3089906 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAAYEPAR MGYG000000089_01614 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG1053@1|root,COG1053@2|Bacteria,2J6FD@203691|Spirochaetes 1.0 203691|Spirochaetes 1.0 C 1.0 PFAM fumarate reductase succinate dehydrogenase flavoprotein 1.0 - 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239 1.0 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 1.0 M00009,M00011,M00149,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000089_01614 1.0 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 928789 0 0 0 0 1578481 0 0 0 0 1199035 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 287613 0 0 0 0 785505 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207727 0 0 0 0 0 0 0 0 0 0 +AANAEELEALR MGYG000002171_01913;MGYG000002438_03714;MGYG000000138_03867;MGYG000000243_00008;MGYG000004797_01609 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0016@1|root,COG0016@2|Bacteria,4NF8I@976|Bacteroidetes,2FNZN@200643|Bacteroidia,4AKA6@815|Bacteroidaceae 0.6 976|Bacteroidetes 1.0 J 1.0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily 1.0 pheS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.20 1.0 ko:K01889 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03660 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Phe_tRNA-synt_N,tRNA-synt_2d 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_01913 0.2 phenylalanine--tRNA ligase. phenylalanyl-tRNA synthetase. - ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01889:FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] 1.0 none 1.0 275281 87009 226671 0 0 402417 0 0 242400 0 0 480689 0 221542 0 0 0 0 350410 0 248337 209744 0 393282 329257 486942 0 0 0 0 0 0 189499 0 0 0 310165 137970 665986 370581 752631 0 0 680753 0 0 672096 0 0 1294599 0 792672 0 0 0 0 745185 0 1090920 601755 0 537302 785736 854037 0 0 0 0 0 0 686735 0 0 0 706774 579300 208536 0 517678 0 0 437356 0 0 531073 0 0 618714 0 340474 0 0 0 0 458245 0 545967 0 0 419896 210718 231607 0 0 0 0 0 0 339641 0 0 0 342892 295430 435863 687931 1070626 0 0 260353 0 0 434557 0 0 986298 0 694476 0 0 0 0 393451 0 1342909 631570 0 447936 757438 891312 0 0 0 0 0 0 766574 0 0 0 780498 0 505552 236090 0 0 0 601818 0 0 603082 0 0 948605 0 380461 0 0 0 0 305506 0 1078644 423511 0 640822 537233 303867 0 0 0 0 0 0 295527 0 0 0 622957 217754 +AANAEIPIIFL MGYG000000029_00379;MGYG000001780_04718 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia,4AKWQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 1.0 rprY 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Response_reg,Trans_reg_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000029_00379 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84605 0 0 0 0 0 0 0 95555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 98267 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2684887 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2568462 0 0 0 0 2096225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAEIPIIFLTAK MGYG000000196_03771;MGYG000000243_00835 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0745@1|root,COG0745@2|Bacteria,4NF1I@976|Bacteroidetes,2FNZV@200643|Bacteroidia,4AKWQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain 1.0 rprY 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Response_reg,Trans_reg_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_03771 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15060032 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11829708 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6681574 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAGGVA(Ala->Thr)TSALEMSQNSER MGYG000002945_01156;MGYG000000080_02138;MGYG000004689_01489;MGYG000000245_02477;MGYG000000135_03486;MGYG000004839_02530;MGYG000000251_03197;MGYG000000146_00040;MGYG000002212_01108;MGYG000000164_00589;MGYG000000153_01021;MGYG000004296_00383;MGYG000004380_02235;MGYG000000404_01723;MGYG000002517_02750;MGYG000001797_03050;MGYG000000312_01079;MGYG000001637_01313;MGYG000001689_00608;MGYG000000489_02253;MGYG000000280_02447;MGYG000002528_01412;MGYG000003425_04268;MGYG000000076_02271;MGYG000004879_02390;MGYG000000229_01813;MGYG000002670_01100;MGYG000000136_01003;MGYG000002609_02276;MGYG000004719_01514;MGYG000004547_00997;MGYG000003702_00540;MGYG000004055_01618;MGYG000003063_02071;MGYG000000187_02311;MGYG000002279_01299;MGYG000002149_01514;MGYG000002992_01902;MGYG000000271_00907;MGYG000002492_02848;MGYG000002131_02188 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.3170731707317073 186801|Clostridia 0.6829268292682927 C 0.4146341463414634 Belongs to the Glu Leu Phe Val dehydrogenases family 0.4634146341463415 gdhA 0.6829268292682927 - 1.0 1.4.1.3,1.4.1.4 0.6341463414634146 ko:K00261,ko:K00262 0.6341463414634146 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6341463414634146 M00740 0.6829268292682927 R00243,R00248 0.6829268292682927 RC00006,RC02799 0.6829268292682927 ko00000,ko00001,ko00002,ko01000,ko04147 0.6829268292682927 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.6829268292682927 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002945_01156 0.024390243902439025 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6341463414634146 0.6341463414634146 0.6341463414634146 0.6341463414634146 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.6341463414634146 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.6341463414634146 none 1.0 0 0 0 0 0 0 0 332542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724739 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 744822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAGGVATSALE(Cation_Na)MSQNSER MGYG000002945_01156;MGYG000000080_02138;MGYG000004689_01489;MGYG000000245_02477;MGYG000000135_03486;MGYG000004839_02530;MGYG000000251_03197;MGYG000000146_00040;MGYG000002212_01108;MGYG000000164_00589;MGYG000000153_01021;MGYG000004296_00383;MGYG000004380_02235;MGYG000000404_01723;MGYG000002517_02750;MGYG000001797_03050;MGYG000000312_01079;MGYG000001637_01313;MGYG000001689_00608;MGYG000000489_02253;MGYG000000280_02447;MGYG000002528_01412;MGYG000003425_04268;MGYG000000076_02271;MGYG000004879_02390;MGYG000000229_01813;MGYG000002670_01100;MGYG000000136_01003;MGYG000002609_02276;MGYG000004719_01514;MGYG000004547_00997;MGYG000003702_00540;MGYG000004055_01618;MGYG000003063_02071;MGYG000000187_02311;MGYG000002279_01299;MGYG000002149_01514;MGYG000002992_01902;MGYG000000271_00907;MGYG000002492_02848;MGYG000002131_02188 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.3170731707317073 186801|Clostridia 0.6829268292682927 C 0.4146341463414634 Belongs to the Glu Leu Phe Val dehydrogenases family 0.4634146341463415 gdhA 0.6829268292682927 - 1.0 1.4.1.3,1.4.1.4 0.6341463414634146 ko:K00261,ko:K00262 0.6341463414634146 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6341463414634146 M00740 0.6829268292682927 R00243,R00248 0.6829268292682927 RC00006,RC02799 0.6829268292682927 ko00000,ko00001,ko00002,ko01000,ko04147 0.6829268292682927 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.6829268292682927 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002945_01156 0.024390243902439025 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6341463414634146 0.6341463414634146 0.6341463414634146 0.6341463414634146 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.6341463414634146 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.6341463414634146 none 1.0 0 0 0 0 0 0 0 0 0 0 0 3062492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3229349 0 0 0 0 0 0 0 0 0 0 0 0 0 3325033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1686139 0 0 0 0 0 0 0 0 0 0 0 0 0 1990309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1475996 0 0 0 0 0 0 0 0 0 0 0 0 0 573331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 817862 0 0 0 0 0 0 0 0 0 0 0 0 0 1676192 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1240700 0 0 +AANAGGVATSALEM(Oxidation)SQNSER MGYG000002945_01156;MGYG000000080_02138;MGYG000004689_01489;MGYG000000245_02477;MGYG000000135_03486;MGYG000004839_02530;MGYG000000251_03197;MGYG000000146_00040;MGYG000002212_01108;MGYG000000164_00589;MGYG000000153_01021;MGYG000004296_00383;MGYG000004380_02235;MGYG000000404_01723;MGYG000002517_02750;MGYG000001797_03050;MGYG000000312_01079;MGYG000001637_01313;MGYG000001689_00608;MGYG000000489_02253;MGYG000000280_02447;MGYG000002528_01412;MGYG000003425_04268;MGYG000000076_02271;MGYG000004879_02390;MGYG000000229_01813;MGYG000002670_01100;MGYG000000136_01003;MGYG000002609_02276;MGYG000004719_01514;MGYG000004547_00997;MGYG000003702_00540;MGYG000004055_01618;MGYG000003063_02071;MGYG000000187_02311;MGYG000002279_01299;MGYG000002149_01514;MGYG000002992_01902;MGYG000000271_00907;MGYG000002492_02848;MGYG000002131_02188 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.3170731707317073 186801|Clostridia 0.6829268292682927 C 0.4146341463414634 Belongs to the Glu Leu Phe Val dehydrogenases family 0.4634146341463415 gdhA 0.6829268292682927 - 1.0 1.4.1.3,1.4.1.4 0.6341463414634146 ko:K00261,ko:K00262 0.6341463414634146 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6341463414634146 M00740 0.6829268292682927 R00243,R00248 0.6829268292682927 RC00006,RC02799 0.6829268292682927 ko00000,ko00001,ko00002,ko01000,ko04147 0.6829268292682927 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.6829268292682927 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002945_01156 0.024390243902439025 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6341463414634146 0.6341463414634146 0.6341463414634146 0.6341463414634146 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.6341463414634146 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.6341463414634146 none 1.0 0 0 0 173802 0 0 0 0 0 0 0 0 0 0 386868 0 700439 1010608 0 0 0 0 390568 0 0 0 0 351164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 224086 0 0 0 0 450654 0 0 0 0 443934 0 0 0 0 0 0 0 0 0 0 0 0 0 283688 0 0 0 0 0 0 0 0 0 0 324771 0 308967 339645 0 0 0 0 411152 0 0 0 0 485628 0 0 0 0 0 0 0 0 0 0 0 0 0 164179 0 0 0 0 0 0 0 0 0 0 405227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239860 0 0 0 0 0 0 0 0 0 0 362354 0 412743 253299 0 0 0 0 326326 0 0 0 0 290282 0 0 0 0 0 0 0 0 0 0 +AANAGGVATSALEMC(Carbamidomethyl)QNSAR MGYG000000184_00534;MGYG000003455_00764;MGYG000001338_02192 life d__Bacteria 0.6667 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 0.6666666666666666 C 0.6666666666666666 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 - 0.6666666666666666 1.4.1.3,1.4.1.4 0.6666666666666666 ko:K00261,ko:K00262 0.6666666666666666 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6666666666666666 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_00534 0.3333333333333333 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.6666666666666666 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.6666666666666666 none 1.0 341531 1388575 859207 0 1017787 426936 440384 594295 0 0 1158103 0 960384 0 0 830240 568240 802701 0 0 0 373053 560523 0 0 321370 314568 1018752 0 453935 570631 1469228 480901 0 0 0 406118 486330 451747 2445146 0 0 793468 0 356777 390564 0 0 425175 0 419411 0 0 0 0 1579224 0 0 0 0 1106801 446496 0 0 567903 1202857 0 0 2479560 1110103 0 0 0 0 0 0 327964 2061289 525410 0 294586 0 339166 431880 0 0 334654 0 689183 0 0 508953 310830 0 0 0 0 544139 369080 0 0 0 344087 745396 0 537247 593803 1480163 973182 0 825964 0 555022 460954 0 0 0 0 0 0 0 0 0 0 415285 0 0 0 0 0 0 417020 0 0 0 0 0 0 0 0 0 0 0 346994 0 0 0 0 0 0 0 0 456153 4099456 2021592 0 980464 475614 734667 647025 0 0 781227 0 1110737 0 0 915338 289872 369078 0 0 0 636569 998146 531053 0 556234 638759 916132 0 690120 2517101 3261566 2934519 0 662116 0 525641 1670320 +AANAGGVATSALEMS(Methyl[S](Ser->Thr)QNSMR MGYG000003142_02931;MGYG000000301_02376;MGYG000004022_00658;MGYG000001658_02349;MGYG000000201_03244;MGYG000003427_02564;MGYG000000142_02223;MGYG000002098_00876;MGYG000003012_01963 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.5555555555555556 186801|Clostridia 1.0 C 0.6666666666666666 Belongs to the Glu Leu Phe Val dehydrogenases family 0.7777777777777778 gdhA 0.8888888888888888 - 0.8888888888888888 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003142_02931 0.1111111111111111 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 311903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 449325 0 0 912375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1125216 0 1150439 0 0 0 0 0 0 0 0 1652732 0 0 0 0 342621 +AANAGGVATSALEMSQNSER MGYG000002945_01156;MGYG000000080_02138;MGYG000004689_01489;MGYG000000245_02477;MGYG000000135_03486;MGYG000004839_02530;MGYG000000251_03197;MGYG000000146_00040;MGYG000002212_01108;MGYG000000164_00589;MGYG000000153_01021;MGYG000004296_00383;MGYG000004380_02235;MGYG000000404_01723;MGYG000002517_02750;MGYG000001797_03050;MGYG000000312_01079;MGYG000001637_01313;MGYG000001689_00608;MGYG000000489_02253;MGYG000000280_02447;MGYG000002528_01412;MGYG000003425_04268;MGYG000000076_02271;MGYG000004879_02390;MGYG000000229_01813;MGYG000002670_01100;MGYG000000136_01003;MGYG000002609_02276;MGYG000004719_01514;MGYG000004547_00997;MGYG000003702_00540;MGYG000004055_01618;MGYG000003063_02071;MGYG000000187_02311;MGYG000002279_01299;MGYG000002149_01514;MGYG000002992_01902;MGYG000000271_00907;MGYG000002492_02848;MGYG000002131_02188 order d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.3170731707317073 186801|Clostridia 0.6829268292682927 C 0.4146341463414634 Belongs to the Glu Leu Phe Val dehydrogenases family 0.4634146341463415 gdhA 0.6829268292682927 - 1.0 1.4.1.3,1.4.1.4 0.6341463414634146 ko:K00261,ko:K00262 0.6341463414634146 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6341463414634146 M00740 0.6829268292682927 R00243,R00248 0.6829268292682927 RC00006,RC02799 0.6829268292682927 ko00000,ko00001,ko00002,ko01000,ko04147 0.6829268292682927 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.6829268292682927 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002945_01156 0.024390243902439025 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6341463414634146 0.6341463414634146 0.6341463414634146 0.6341463414634146 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.6341463414634146 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.6341463414634146 none 1.0 3989835 3366014 2810549 6051349 3713600 3569569 2938878 4322387 3677901 4336497 6913253 3578488 4499371 3145359 3602268 4008419 4350661 5607156 2436534 4342940 4146698 3500212 5657905 0 3832789 3865581 4408982 7081206 3848953 4116513 0 2631203 2048673 3046141 3948950 3277806 3785112 2028602 1505172 2369460 1464547 1761049 1861562 1287654 1399179 1646284 1294988 1347692 1254482 1211568 1569278 1544454 1380094 1526392 1409936 8526149 1251799 1701014 1363231 1286229 5718090 1936941 1254440 1630426 1327235 8633214 2939276 1556874 2779737 1741309 1340293 1423786 1426826 1479323 1546734 1429297 5305855 2499009 4111579 3755561 1943745 2051315 3204351 3739540 2688372 6192752 2690546 3926573 2936750 3709994 4978641 3612024 4384966 2375792 3283226 4440256 3286480 2917467 3862560 2441044 4041494 7986301 4367297 5985550 3107649 3274742 1991245 3062881 4712213 4161761 3941398 3086467 4771621 3565469 2434771 1590887 642440 2141923 1221595 578376 1108181 1981924 2477806 618891 948024 1367751 620098 2742917 2583548 1352671 2038046 1658877 1359263 1725663 2965576 408816 1343612 527331 2804301 2067468 1004670 546925 426222 1514639 670639 1588633 603758 1585700 2527233 2203154 2368751 609030 4366490 5912803 8171822 919572 2500537 5724961 4434235 4340166 4455011 9549044 4903449 5955747 2496993 6895172 10414742 4874909 9219738 3507835 7127665 3553485 4301299 5174686 4195899 4968588 5607251 4356549 6177467 4279433 4645735 3087871 5313681 2204329 7155005 4902962 4727411 7336397 6548432 5275373 +AANAGGVATSALEMSQNSMR MGYG000003142_02931;MGYG000000301_02376;MGYG000004022_00658;MGYG000001658_02349;MGYG000000201_03244;MGYG000003427_02564;MGYG000000142_02223;MGYG000002098_00876;MGYG000003012_01963 phylum d__Bacteria|p__Firmicutes_A 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.5555555555555556 186801|Clostridia 1.0 C 0.6666666666666666 Belongs to the Glu Leu Phe Val dehydrogenases family 0.7777777777777778 gdhA 0.8888888888888888 - 0.8888888888888888 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003142_02931 0.1111111111111111 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 257021 368324 584838 332787 512194 620203 164543 767402 0 556040 1362118 492501 375409 0 334279 493136 829364 260879 0 349991 490600 348340 491837 168735 385402 126618 350059 756112 261272 656754 0 180454 444902 451046 352959 279211 249783 460327 660516 1014440 682736 487588 1283147 522760 1101660 849933 0 613381 1584629 464600 725034 448202 388212 491437 483934 817779 553186 849016 210330 0 520115 0 567108 817599 1569355 749303 787232 853941 0 1025165 821511 1029886 901474 1056483 721791 773007 602743 626125 578871 328837 279479 460520 409139 496528 0 329276 371523 434825 488901 339486 507205 451108 314603 0 357608 396925 285395 702896 396791 365441 519477 451385 451256 596376 436233 365679 329738 474135 1039678 671690 496583 245637 557549 415074 251656 253793 0 0 388499 0 0 0 0 0 0 0 0 82630 248721 0 225305 0 0 0 0 0 0 0 0 0 0 0 0 220479 0 155738 0 0 0 0 0 0 624943 613723 807864 642452 193854 671292 777871 573511 0 1134860 1014510 900923 293969 1240815 982438 349087 676299 315995 835525 274484 909766 0 425293 938831 915626 596271 1080983 580039 1079565 217410 789139 721033 1818795 734856 658652 888830 568812 840307 +AANAGGVATSALEMSQNSQR MGYG000004285_01380;MGYG000004642_00466;MGYG000000278_03573;MGYG000000258_01047;MGYG000000171_00025 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia 0.6 186801|Clostridia 1.0 C 0.8 Belongs to the Glu Leu Phe Val dehydrogenases family 0.8 gdhA 0.8 - 1.0 1.4.1.3,1.4.1.4 0.8 ko:K00261,ko:K00262 0.8 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.8 M00740 0.8 R00243,R00248 0.8 RC00006,RC02799 0.8 ko00000,ko00001,ko00002,ko01000,ko04147 0.8 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004285_01380 0.2 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.8 0.8 0.8 0.8 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.8 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.8 none 1.0 339755 0 313940 231144 0 361083 386123 233890 0 797278 0 425154 232006 0 374920 272912 0 0 321683 306762 0 435995 0 230083 419452 476776 365966 0 525987 321989 0 439462 0 400402 0 419553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164898 0 0 524001 0 0 0 0 473133 0 0 138060 196517 305358 0 0 0 0 0 0 0 0 0 0 1381444 0 721733 839939 0 738462 754221 962660 0 835709 0 931029 864242 0 974907 908054 0 484140 863715 1170609 0 1199179 1220573 743384 1071660 1086008 1071574 1118520 726867 891287 0 586384 976476 1094765 1317640 776982 1203063 976326 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 192480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 112047 0 0 0 0 0 0 0 0 0 0 0 0 249339 0 0 0 0 183896 0 0 0 0 0 0 0 0 0 0 0 0 0 355620 +AANAGGVATSALEMSQNSQRLSWTFEEVDAK MGYG000000036_02065 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Acutalibacteraceae|g__Pseudoruminococcus|s__Pseudoruminococcus massiliensis|m__MGYG000000036 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,268E7@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdhA 1.0 - 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000036_02065 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 1456585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAGGVATSGLEM(Oxidation)SQNSER MGYG000002074_01624;MGYG000000089_00679;MGYG000002881_00615;MGYG000002274_02026 domain d__Bacteria 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae 0.5 186801|Clostridia 0.75 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 0.75 gdhA 0.5 - 1.0 1.4.1.3,1.4.1.4 0.5 ko:K00261,ko:K00262 0.5 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.5 - 0.5 R00243,R00248 0.5 RC00006,RC02799 0.75 ko00000,ko00001,ko01000 0.5 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002074_01624 0.25 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.5 0.5 0.5 0.5 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.5 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 670801 0 0 0 0 396766 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAGGVATSGLEMAQNAAR MGYG000002502_02076;MGYG000002506_01152;MGYG000002534_02260;MGYG000002323_01826;MGYG000002494_01678;MGYG000002477_03414 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0334@1|root,COG0334@2|Bacteria,1MUMF@1224|Proteobacteria,1RPUZ@1236|Gammaproteobacteria 0.6666666666666666 1236|Gammaproteobacteria 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.3,1.4.1.4 0.6666666666666666 ko:K00261,ko:K00262 0.6666666666666666 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.6666666666666666 M00740 0.6666666666666666 R00243,R00248 0.6666666666666666 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 0.6666666666666666 - 1.0 - 1.0 iECH74115_1262.ECH74115_2481,iECSP_1301.ECSP_2329,iECs_1301.ECs2467,iG2583_1286.G2583_2207,iPC815.YPO3971,iSDY_1059.SDY_1514,iYL1228.KPN_01210,iZ_1308.Z2793 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002502_02076 0.16666666666666666 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.6666666666666666 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 96429 0 0 0 165744 0 0 0 0 0 460323 1184115 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 155389 0 0 1312787 1437772 1932113 0 2001357 1639758 1547449 638130 841929 2233583 0 0 1653772 1817902 661494 2112396 2803380 0 10585677 1753015 3110391 2065721 0 1825675 2586009 979792 825047 0 4405809 3434167 0 0 2209542 799012 725717 1201433 832466 1657536 0 0 314727 0 0 633648 130664 0 0 0 0 0 0 0 0 0 0 0 1125972 528456 0 629696 0 345284 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 306731 0 0 0 0 0 0 0 0 0 0 0 0 0 487235 331990 392120 0 346094 0 0 0 0 0 0 232130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAGGVATSGLEMSQNSER MGYG000002074_01624;MGYG000000089_00679;MGYG000002881_00615;MGYG000002274_02026 domain d__Bacteria 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae 0.5 186801|Clostridia 0.75 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 0.75 gdhA 0.5 - 1.0 1.4.1.3,1.4.1.4 0.5 ko:K00261,ko:K00262 0.5 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 0.5 - 0.5 R00243,R00248 0.5 RC00006,RC02799 0.75 ko00000,ko00001,ko01000 0.5 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002074_01624 0.25 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 0.5 0.5 0.5 0.5 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 0.5 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 0.5 none 1.0 0 0 0 0 0 0 460080 0 0 0 0 0 0 0 0 0 0 2271368 0 0 0 0 3117722 0 0 0 0 2391600 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 850011 0 0 0 0 748873 0 0 0 0 963878 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 168354 0 0 0 0 0 0 0 0 0 0 403567 0 0 0 0 590093 0 0 0 0 857431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 357290 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 184733 0 0 0 0 0 0 0 0 0 0 949867 0 0 0 0 1422642 0 0 0 0 1374226 0 0 0 0 0 0 0 0 0 0 +AANAGGVATSGLEMSQNSLR MGYG000003937_01839 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 - 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_01839 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 475191 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 402320 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 835622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAGGVATSGLEMTQNSMR MGYG000000074_01576;MGYG000004658_01015 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,22V1Z@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01576 0.5 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 1.0 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 366548 0 0 0 0 0 0 0 0 0 0 0 0 0 703566 0 0 0 855859 0 0 0 0 0 0 1780043 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 487867 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 637984 0 0 0 0 0 0 0 0 0 0 0 0 0 964493 0 0 0 0 0 0 0 0 0 0 737932 0 0 0 0 0 0 0 +AANAGGVATSGLEQSQNALR MGYG000004087_01470;MGYG000000198_05072;MGYG000000179_02572;MGYG000001954_01682;MGYG000001311_01200 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,268E7@186813|unclassified Clostridiales 0.8 186801|Clostridia 1.0 E 0.8 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 0.8 gdhA 1.0 - 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004087_01470 0.2 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 1129606 0 0 732094 0 0 505751 0 636621 633028 0 0 0 994890 815555 118958 531220 0 527491 1300058 841123 259269 0 0 485364 645922 445102 0 1005973 0 0 0 0 323879 0 1003105 684836 0 0 0 0 248737 0 0 0 0 0 0 0 0 0 0 0 0 0 0 194762 0 0 0 0 0 0 234411 223274 0 385566 0 0 0 0 0 0 249884 166849 0 1161447 0 301180 1576220 0 289510 679743 0 742355 835825 0 516615 0 834229 1247524 393190 857779 0 723990 876610 743465 667971 0 0 187064 1084574 1057017 0 672149 0 0 0 402728 849305 0 930074 844563 501487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 834870 603842 977233 1606024 0 352073 986065 0 1012781 1098537 0 965898 0 1925966 1103951 551352 1195288 0 635517 727767 1075936 853173 0 1322106 940639 1113858 1532227 0 1704877 0 807613 0 1416277 1130232 0 1380183 1047231 865979 +AANAGGVATSGLEQSQNSLR MGYG000000242_02251 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,268E7@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 1.0 gdhA 1.0 - 1.0 1.4.1.3,1.4.1.4 1.0 ko:K00261,ko:K00262 1.0 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 1.0 M00740 1.0 R00243,R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000242_02251 1.0 glutamate dehydrogenase [NAD(P)(+)]. | glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - (1) H2O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH4(+). (2) H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). | H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Carbon metabolism|Necroptosis|Proximal tubule bicarbonate reclamation 1.0 K00261:GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]|K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 943905 0 0 0 0 1136453 0 0 0 0 0 0 0 0 0 0 +AANAGGVAVSGLEMSQNSER MGYG000001056_01499;MGYG000002603_01071;MGYG000003493_00641;MGYG000001770_00555;MGYG000003697_02127;MGYG000002293_02206 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001056_01499 0.16666666666666666 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 1.0 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294361 0 0 0 0 123773 0 0 0 0 0 0 0 0 0 0 0 468310 578481 0 0 222599 540922 0 526993 0 0 0 241989 0 346754 0 0 0 0 0 0 654293 171276 0 424861 711866 621634 0 0 501916 854691 0 747300 204742 374096 267325 0 426964 1092561 976792 3820077 0 1405517 2439892 1029451 1162056 1043390 0 3608860 979041 1858284 883421 1177913 1377831 0 4221458 0 0 795873 4001075 6148145 2192147 1339851 1271588 1023928 1358967 0 870140 1102121 1227296 2916850 1283199 1122950 1333239 1181499 2462002 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAGGVAVSGLEMSQNSMR MGYG000000254_02292;MGYG000000168_02503 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Marinifilaceae 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,22WFZ@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 - 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000254_02292 0.5 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 1.0 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 1205640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400722 0 0 589589 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 434695 0 0 0 0 560849 0 0 0 0 388643 0 0 0 0 0 0 0 0 0 0 0 0 0 572219 0 0 0 0 0 0 0 0 0 0 0 0 0 727812 0 0 0 0 685297 0 0 0 0 279818 0 0 503219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365494 0 0 0 0 0 0 0 0 0 0 0 0 0 583443 0 0 0 0 576496 0 0 0 0 517351 0 0 0 0 0 0 0 0 0 0 +AANAGGVAVSGLEMSQNSYR MGYG000003683_01480 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium pseudocatenulatum|m__MGYG000003683 1.0 COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria,4CYTN@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01480 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 1.0 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 301025 0 0 0 0 0 0 0 0 0 178528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 379533 0 0 0 0 0 0 0 0 0 0 0 866790 0 0 0 0 210434 771470 0 0 0 340478 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314475 0 0 0 0 0 0 0 0 0 0 0 1431550 0 0 0 0 0 0 0 0 0 766227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAGGVSVSGLEM(Oxidation)TQNSIK MGYG000003693_00557;MGYG000001313_03295;MGYG000001789_00079;MGYG000002549_04353;MGYG000001370_01162;MGYG000000098_03405;MGYG000003312_01614;MGYG000001787_01270;MGYG000000415_01192;MGYG000001378_04299;MGYG000000196_02414;MGYG000000043_00874;MGYG000002455_00090;MGYG000002561_00600;MGYG000001461_03124;MGYG000000029_00569;MGYG000001346_00984;MGYG000001599_00620;MGYG000000042_02165;MGYG000000236_00945;MGYG000004797_02295;MGYG000000243_02148;MGYG000004899_01533;MGYG000002281_02120;MGYG000001835_02312;MGYG000002478_00271 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AKTV@815|Bacteroidaceae 0.8461538461538461 976|Bacteroidetes 1.0 C 0.8461538461538461 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_00557 0.038461538461538464 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 1.0 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 453520 0 0 0 0 499852 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 370707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 415018 0 0 0 0 364230 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 708631 0 0 0 0 299026 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAGGVSVSGLEMSQNSER MGYG000002540_00149 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Paraprevotella|s__Paraprevotella clara|m__MGYG000002540 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002540_00149 1.0 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 1.0 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAGGVSVSGLEMTQN(Deamidated)SIK MGYG000003693_00557;MGYG000001313_03295;MGYG000001789_00079;MGYG000002549_04353;MGYG000001370_01162;MGYG000000098_03405;MGYG000003312_01614;MGYG000001787_01270;MGYG000000415_01192;MGYG000001378_04299;MGYG000000196_02414;MGYG000000043_00874;MGYG000002455_00090;MGYG000002561_00600;MGYG000001461_03124;MGYG000000029_00569;MGYG000001346_00984;MGYG000001599_00620;MGYG000000042_02165;MGYG000000236_00945;MGYG000004797_02295;MGYG000000243_02148;MGYG000004899_01533;MGYG000002281_02120;MGYG000001835_02312;MGYG000002478_00271 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AKTV@815|Bacteroidaceae 0.8461538461538461 976|Bacteroidetes 1.0 C 0.8461538461538461 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_00557 0.038461538461538464 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 1.0 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 323617 0 363430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 620616 0 803748 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 462379 0 387839 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640487 0 679934 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANAGGVSVSGLEMTQNAQK MGYG000002438_00724;MGYG000002575_00603 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,22XFA@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00724 0.5 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 1.0 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 0 0 0 0 296802 0 0 0 0 0 0 661983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292451 0 0 0 0 0 0 1579716 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394228 0 0 0 0 0 0 0 431043 0 0 0 0 0 0 0 0 0 366299 415113 0 0 2509826 0 0 0 0 0 0 316912 0 0 0 0 366167 0 0 0 553615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 925902 0 0 1176617 0 0 0 0 0 0 2345596 736929 0 0 1111141 0 995502 0 0 3492903 0 957751 0 0 0 0 878555 0 3028819 0 3121821 0 0 0 0 0 0 +AANAGGVSVSGLEMTQNSIK MGYG000003693_00557;MGYG000001313_03295;MGYG000001789_00079;MGYG000002549_04353;MGYG000001370_01162;MGYG000000098_03405;MGYG000003312_01614;MGYG000001787_01270;MGYG000000415_01192;MGYG000001378_04299;MGYG000000196_02414;MGYG000000043_00874;MGYG000002455_00090;MGYG000002561_00600;MGYG000001461_03124;MGYG000000029_00569;MGYG000001346_00984;MGYG000001599_00620;MGYG000000042_02165;MGYG000000236_00945;MGYG000004797_02295;MGYG000000243_02148;MGYG000004899_01533;MGYG000002281_02120;MGYG000001835_02312;MGYG000002478_00271 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0334@1|root,COG0334@2|Bacteria,4NEBH@976|Bacteroidetes,2FM43@200643|Bacteroidia,4AKTV@815|Bacteroidaceae 0.8461538461538461 976|Bacteroidetes 1.0 C 0.8461538461538461 Belongs to the Glu Leu Phe Val dehydrogenases family 1.0 gdhA 1.0 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 1.4.1.4 1.0 ko:K00262 1.0 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 1.0 - 1.0 R00248 1.0 RC00006,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ELFV_dehydrog,ELFV_dehydrog_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_00557 0.038461538461538464 glutamate dehydrogenase (NADP(+)). glutamic dehydrogenase. - H2O + L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + NADPH + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways 1.0 K00262:E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4] 1.0 none 1.0 1400842 1684854 4566249 1743347 2560685 1606063 1776330 1147943 1460758 1154817 5885749 1255740 5150784 1024834 823646 2950110 1348476 836425 783660 871662 1152474 1267474 1699027 1652206 940217 1383429 1431277 1496521 1337011 1511896 2721467 1725834 5185023 1281142 1134743 1544079 1405978 4786631 782075 931844 1279919 1153077 2843556 1489996 1004468 785879 940698 1115017 6891194 1278949 7303127 1117278 1022487 3432920 1356473 1622238 831079 940464 1078388 1813838 2382902 1414519 1023048 1247425 1210839 1878893 1056538 1193157 1089883 1411040 0 730051 993564 1092543 886984 1151646 1060426 839678 2133591 1648401 2165184 2085109 1630735 1114718 1677566 984056 6665501 1359797 4612409 1264656 1038780 2799698 0 3628907 1082471 932058 953440 1145869 3163030 1412354 947987 1276627 1179914 2493139 1040835 1217022 1590969 903777 1504756 1057881 1344658 1596843 1512365 2087771 384395 0 301493 0 0 384855 424897 334781 168761 0 1045898 527159 1107490 393659 419731 354118 0 54784 0 0 456794 0 799009 0 666701 569836 400585 0 0 0 112767 0 0 753910 495789 409573 420512 0 799860 902026 837147 1167200 1610899 1599378 1198056 959273 1433034 969647 8380406 1319930 8113162 1056679 1091796 3412144 1342046 3563542 771546 1147465 921847 1473983 3132963 1909071 1206304 1271266 1099586 2517388 1152667 1702125 1328001 1213462 915051 1242653 1336836 1161208 2115411 1282968 +AANAIDALK MGYG000003514_00092 genome d__Bacteria|p__Fibrobacterota|c__Fibrobacteria|o__Fibrobacterales|f__Fibrobacteraceae|g__Fibrobacter_A|s__Fibrobacter_A intestinalis|m__MGYG000003514 1.0 COG0459@1|root,COG0459@2|Bacteria 1.0 2|Bacteria 1.0 O 1.0 protein refolding 1.0 groL 1.0 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 1.0 - 1.0 ko:K04077 1.0 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 - 1.0 - 1.0 - 1.0 Cpn60_TCP1,Response_reg 1.0 - 1.0 - 1.0 - 1.0 GH13 1.0 MGYG000003514_00092 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Type I diabetes mellitus|Legionellosis|Tuberculosis 1.0 K04077:groEL, HSPD1; chaperonin GroEL [EC:5.6.1.7] 1.0 none 1.0 2165502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2566673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANASYYPGVR MGYG000003697_00736 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2G3FU@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_00736 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 150458 0 0 161327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1045856 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1073066 0 0 0 0 1199711 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANATQVVK MGYG000003697_02150;MGYG000002603_01099 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0246@1|root,COG0246@2|Bacteria,4NEMT@976|Bacteroidetes,2FP8Z@200643|Bacteroidia,4ATAV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Mannitol dehydrogenase Rossmann domain 1.0 uxuB 1.0 - 1.0 1.1.1.17,1.1.1.58,1.1.1.67 1.0 ko:K00009,ko:K00041,ko:K00045 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00631 1.0 R00868,R02555,R02703 1.0 RC00085 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Mannitol_dh,Mannitol_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_02150 0.5 mannitol-1-phosphate 5-dehydrogenase. | tagaturonate reductase. | mannitol 2-dehydrogenase. Tagaturonate dehydrogenase. | mannitol dehydrogenase. - D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + H(+) + NADH. | D-altronate + NAD(+) = H(+) + keto-D-tagaturonate + NADH. | D-mannitol + NAD(+) = D-fructose + H(+) + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K00009:mtlD; mannitol-1-phosphate 5-dehydrogenase [EC:1.1.1.17]|K00041:uxaB; tagaturonate reductase [EC:1.1.1.58]|K00045:E1.1.1.67, mtlK; mannitol 2-dehydrogenase [EC:1.1.1.67] 1.0 none 1.0 0 0 0 0 0 236777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 344791 0 169271 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 270524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7289156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13389018 0 12619542 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANATSFEQYK MGYG000001346_01072 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_01072 1.0 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K01802:E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]|K03770:ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1397537 549946 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675292 0 0 0 0 0 339805 1155586 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336255 0 0 0 0 0 0 0 0 0 0 0 958174 0 0 0 0 0 2089124 724532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877981 0 0 0 0 0 0 0 0 0 0 0 374302 0 0 0 0 0 568438 598441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 256879 0 0 0 0 0 0 0 0 0 0 0 579526 0 0 0 0 0 2994815 876640 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 731118 0 0 0 0 0 0 0 +AANATSFNQYK MGYG000001345_01176;MGYG000001378_02418 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0760@1|root,COG0760@2|Bacteria,4NDZZ@976|Bacteroidetes,2FN8C@200643|Bacteroidia,4AKN2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 O 1.0 COG NOG26630 non supervised orthologous group 1.0 ppiD 1.0 - 1.0 5.2.1.8 1.0 ko:K01802,ko:K03770 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Rotamase,Rotamase_2,Rotamase_3,SurA_N_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001345_01176 0.5 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K01802:E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]|K03770:ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 330791 0 0 0 0 1160525 0 0 0 0 0 0 0 0 0 0 252185 0 410772 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218190 0 0 0 0 698332 0 0 0 0 0 0 0 0 0 0 144387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 403549 0 0 0 0 407612 0 0 0 0 0 0 0 0 0 0 271243 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488905 0 0 0 0 923635 0 0 0 0 0 0 0 0 0 0 620461 0 501719 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANDDLLNSFWLLDSEKGEAR MGYG000002534_03664;MGYG000002494_04114 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3445@1|root,COG3445@2|Bacteria,1RDRB@1224|Proteobacteria,1S45G@1236|Gammaproteobacteria,3X2H1@547|Enterobacter 0.5 1236|Gammaproteobacteria 1.0 S 1.0 Acts as a radical domain for damaged PFL and possibly other radical proteins 1.0 grcA 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008861,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.0 - 1.0 ko:K06866 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 iSF_1195.SF2641,iSFxv_1172.SFxv_2898,iS_1188.S2814 1.0 Gly_radical 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002534_03664 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06866:grcA; autonomous glycyl radical cofactor 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 38219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1419123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 488673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANDELSK MGYG000002438_03857 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG2885@1|root,COG2885@2|Bacteria,4NKQC@976|Bacteroidetes,2FRBK@200643|Bacteroidia,22X13@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 - 1.0 GO:0001871,GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0006810,GO:0008150,GO:0015267,GO:0015288,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030246,GO:0030247,GO:0051179,GO:0051234,GO:0055085 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_03857 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 780579 288164 454919 0 162201 409824 1046448 320870 619957 831868 572096 1857784 0 0 0 407335 436440 382849 830690 0 106885 386064 186604 1175950 0 594837 679058 118690 0 612547 0 662648 288361 0 696285 885186 398486 244091 728569 353718 1146128 0 814541 859258 742809 1347194 912161 1062234 1225332 5550749 0 0 0 944560 834417 169644 484532 0 4748079 427583 314989 914768 0 1611853 1280126 870139 0 3979918 0 1789853 332816 0 916244 639913 1122914 899237 164452 746680 506354 0 593933 580234 283527 0 324239 518198 542278 909355 0 0 0 491418 445202 43010 593378 0 4086191 451747 273015 449086 0 345349 443116 124252 0 1223639 0 1270913 425359 0 0 507613 532150 424660 437613 760818 394471 0 0 555510 446959 93105 522513 0 469899 1452969 0 0 0 513806 419917 340305 644342 0 2497391 392754 0 485622 0 819389 723534 1875776 0 1711878 0 1541970 358593 0 257377 185908 633424 395094 2438735 1923638 1174243 0 2593182 1152801 2188775 1679983 2416476 2582761 3786432 3192857 0 0 0 2547393 1517654 3251513 1684600 0 10002959 1912354 3000778 2258703 0 2981996 2845811 1101769 0 6952350 0 2447978 961704 0 4870697 2987175 3422778 2363932 +AANDIN(Deamidated)LKALNK MGYG000004658_01702;MGYG000000074_00133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004658_01702 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2099476 0 0 0 0 0 0 0 0 0 0 0 0 1894221 0 0 0 0 0 0 0 0 0 0 0 0 2354356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANDINLK MGYG000004658_01702;MGYG000000074_00133 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0457@1|root,COG2885@1|root,COG0457@2|Bacteria,COG2885@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22UA2@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004658_01702 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 438026 127477 575378 0 339886 0 0 0 0 0 269834 0 402144 602066 234780 0 126725 76106 437986 0 0 0 0 269310 0 0 0 0 319196 363668 0 0 0 0 85435 780019 4290749 2802561 4440930 4394456 3000720 2264579 2459726 3590288 5226431 3774733 0 3353168 1716433 0 3895377 2943514 3129340 0 3795412 5386300 3755301 2253195 0 1636251 2441694 3405608 3895699 0 0 3459318 2157716 2925410 4016368 0 4878951 0 162073 4257418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1863511 892058 1653581 1683124 1709783 1325622 2145845 1532844 1660848 1371167 0 1787025 622515 0 2202468 875877 1409815 0 1870461 2297860 1608010 0 0 0 1477132 1860700 1573412 0 0 2102292 972146 1429213 1760893 0 2457611 0 1837303 666966 13079119 9178732 15322063 21581114 25492069 23209888 15788160 11726503 21172496 14176828 0 14957173 19150682 0 11878058 16377225 14618665 0 18613634 29125453 11236875 15143756 0 13436519 17250926 28237938 9386213 0 0 28321729 14865280 9288345 6838922 0 9666610 0 20112628 17632440 +AANDLILSK MGYG000003452_00078 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium ruminantium|m__MGYG000003452 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003452_00078 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]|K15515:sauS; sulfoacetaldehyde dehydrogenase [EC:1.2.1.81] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6552063 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANDLVLSK MGYG000001490_00318;MGYG000001292_02366;MGYG000003683_01140;MGYG000002469_01773 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,2GJI2@201174|Actinobacteria,4CZ8F@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10,1.2.1.81 1.0 ko:K04072,ko:K15515 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001490_00318 0.25 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). | sulfoacetaldehyde dehydrogenase (acylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. | The enzyme is involved in degradation of sulfoacetate.-!-In this pathway the reaction is catalyzed in the reverse direction.-!-The enzyme is specific for sulfoacetaldehyde and NADP(+). (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. | CoA + NADP(+) + sulfoacetaldehyde = H(+) + NADPH + sulfoacetyl-CoA. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]|K15515:sauS; sulfoacetaldehyde dehydrogenase [EC:1.2.1.81] 1.0 none 1.0 0 0 6172664 0 0 0 0 0 0 0 0 0 973005 0 0 0 0 6197456 0 0 0 0 0 0 0 0 0 0 1707682 0 1223666 0 4385990 340718 0 473335 0 5077036 0 2553600 13960103 0 0 4877325 0 0 0 0 0 0 3611223 0 0 0 0 8061336 0 0 0 3098099 0 7862888 0 0 0 6513362 1907243 0 12050032 0 10715512 1904707 0 1720938 0 19589903 0 1738561 5098553 0 0 1262961 0 0 0 0 0 0 0 0 0 0 0 1205346 0 0 0 1434241 1657187 1195590 0 0 0 0 1350340 0 1806859 0 13161344 2456207 0 1110475 0 5264186 0 0 0 0 0 633602 0 0 0 0 0 0 960095 0 0 0 0 3728631 0 0 0 0 475496 1096948 0 0 0 0 0 0 0 0 0 920159 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 613608 0 0 0 0 0 0 0 291714 0 411398 0 0 0 0 0 +AANDMGVIC(Carbamidomethyl)GVTTNPSLIAK MGYG000001338_02857 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,3XYWX@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway 1.0 tal 1.0 - 1.0 2.2.1.2 1.0 ko:K00616 1.0 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007 1.0 R01827 1.0 RC00439,RC00604 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02857 1.0 transaldolase. glycerone transferase. - D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D- fructose 6-phosphate + D-erythrose 4-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00616:TALDO1, talB, talA; transaldolase [EC:2.2.1.2] 1.0 none 1.0 0 1170690 914389 853398 959002 616668 0 1238966 0 0 0 0 1065676 0 0 901077 801784 454360 0 0 0 778950 811784 426878 0 0 0 939170 915565 0 0 0 418240 0 0 0 0 540688 0 1685899 0 459309 0 140829 0 376765 0 0 0 0 388025 0 0 0 0 1330643 0 0 0 0 1153263 588677 0 0 0 1250947 0 0 0 0 0 0 0 0 0 0 0 1057689 0 820264 0 0 0 480360 0 0 0 0 0 0 0 571959 482741 237271 0 0 0 0 473114 0 0 0 0 245104 0 0 0 0 0 0 0 0 0 835282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 127755 0 0 0 199353 0 0 0 0 0 278031 0 0 0 0 0 0 0 0 0 0 0 1152798 624742 1258791 226784 508609 655539 342101 0 0 0 0 1061011 0 0 488617 300278 435948 0 0 0 298411 762716 276069 0 0 0 981492 306261 0 0 0 1130121 0 0 0 0 916024 +AANDREFAK MGYG000000243_03128;MGYG000002560_00083;MGYG000000042_01472;MGYG000004797_03123;MGYG000001599_00128;MGYG000002478_01519 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03128 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 7131782 6430957 21999907 11428533 13224300 7434972 10589449 6629847 8902639 7200836 8445654 8790134 12902140 8369809 9246900 15186018 9436505 10081698 7915084 6203334 9134560 9309550 10794552 12713898 9022923 9430068 8299525 11439343 8467449 11223243 19723440 10651940 21924482 8608634 9998947 10040861 7523362 19054460 3468621 3128622 3635865 4256146 6661151 4147549 4182209 4496745 3007720 4221556 5936039 4372545 10172970 4294451 4923255 8071664 4608697 2008981 4054517 3654396 4681449 4765035 3216607 3348429 3860525 4629429 4298228 3531856 4252296 4354815 3243589 5027590 4089606 2717114 3748000 3279874 3589262 2923234 2129893 3520750 3828804 3916669 5740462 4843807 2460410 2878085 4183276 3198164 3763534 3729080 8361748 3681318 3279460 5628762 2973909 2262995 3901029 3202153 2950201 3499751 4062972 5784757 3124843 3962701 3367640 6743294 4617213 1913232 5691371 2988964 2841059 1735796 3358658 4561123 3954205 4109214 558310 862507 630606 523882 1086844 1031750 566349 754406 665265 866439 574439 570916 270321 737801 624070 580567 565889 266799 920383 536840 153319 569204 43065 295371 555133 774757 735789 378904 878260 716776 950702 1319608 1173580 312113 785225 619006 787061 719877 3496098 2653732 2762884 3151596 7626288 3679517 3160641 3277483 4744212 1639159 3327840 2282845 7007020 2776287 3350139 5090733 2896398 5580904 3251208 3284781 1725162 2791394 5473062 3303692 3438429 5677423 3082029 2831334 3251025 2227225 3956340 3358305 2577312 3715805 7432241 4987220 5581390 3612641 +AANDREFAKFADSIK MGYG000000243_03128 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03128 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANDREFAKYADAIK MGYG000004797_03123;MGYG000002478_01519 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_03123 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANDSGIC(Carbamidomethyl)K MGYG000000806_02507;MGYG000000133_01552;MGYG000000301_00312;MGYG000002966_01860 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia 1.0 186801|Clostridia 1.0 F 1.0 COG NOG14451 non supervised orthologous group 1.0 - 1.0 - 1.0 2.7.4.25 1.0 ko:K00945 1.0 ko00240,ko01100,map00240,map01100 1.0 M00052 1.0 R00158,R00512,R01665 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Cytidylate_kin2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000806_02507 0.25 (d)CMP kinase. deoxycytidylate kinase. The prokaryotic cytidine monophosphate kinase specifically phosphorylates CMP (or dCMP), using ATP as the preferred phosphoryl donor.-!-Unlike EC 2.7.4.14, a eukaryotic enzyme that phosphorylates UMP and CMP with similar efficiency, the prokaryotic enzyme phosphorylates UMP with very low rates, and this function is catalyzed in prokaryotes by EC 2.7.4.22.-!-The enzyme phosphorylates dCMP nearly as well as it does CMP. (1) ATP + CMP = ADP + CDP. (2) ATP + dCMP = ADP + dCDP. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Metabolic pathways 1.0 K00945:cmk; CMP/dCMP kinase [EC:2.7.4.25] 1.0 none 1.0 329916 220195 578324 516814 0 440230 669578 322649 685200 418425 307053 0 174947 772042 442524 217820 557735 0 0 0 520103 753012 0 534298 475857 111839 586184 0 560220 0 408784 602289 465684 487036 0 150223 515688 605590 0 0 0 0 0 0 0 115956 234743 221187 0 0 0 286097 0 0 373966 0 0 0 0 0 0 206788 127440 385033 0 0 401336 0 284245 283468 85673 91209 0 80993 0 97011 467596 1209263 258118 853166 0 0 0 778401 0 773164 451228 0 719305 564104 693759 0 373136 0 0 0 633838 737077 0 271343 755447 235814 196503 0 285287 0 952975 0 634865 571431 0 684338 0 622693 224150 388192 219165 214390 0 213006 0 0 338567 201495 164023 0 0 261738 235473 168405 870259 0 0 0 0 0 0 157091 0 362160 230673 0 145599 0 0 239095 279722 446608 0 0 216929 0 1440197 1249005 877001 1063185 0 342289 1879019 761021 801585 1782642 1915378 0 815462 2524276 1120496 722573 948104 0 0 0 2104525 833150 0 765794 1123869 1084390 2132678 0 1212434 0 825908 600445 2239529 1236442 0 1582333 915867 872337 +AANEGEKTETVVK MGYG000001636_01005;MGYG000002775_01401;MGYG000000188_00094;MGYG000003122_01642;MGYG000002050_00255;MGYG000002970_01301;MGYG000002968_01697;MGYG000003266_00528;MGYG000002961_01014;MGYG000004681_00342 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CWB2@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 - 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001636_01005 0.1 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 2760153 0 0 1141487 0 0 0 0 0 1547813 0 0 0 0 1642197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 365904 0 0 369675 0 0 0 0 0 723993 0 0 0 0 129915 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477606 0 0 0 0 0 0 0 0 229740 0 0 0 0 1124729 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640842 0 0 1645117 0 0 0 0 0 2244185 0 0 0 0 3266359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71497 0 0 0 0 0 0 0 0 374499 0 0 0 0 267984 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANEGEKTETVVKK MGYG000002775_01401;MGYG000003122_01642;MGYG000002978_01270;MGYG000000333_00407;MGYG000002961_01014;MGYG000004681_00342;MGYG000001718_00765;MGYG000000802_00126;MGYG000001636_01005;MGYG000000188_00094;MGYG000002050_00255;MGYG000002947_00311;MGYG000003274_00534;MGYG000002970_01301;MGYG000002968_01697;MGYG000003266_00528;MGYG000004875_00527;MGYG000002065_00129 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,4CWB2@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bS16 family 1.0 rpsP 1.0 - 1.0 - 1.0 ko:K02959 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S16 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002775_01401 0.05555555555555555 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02959:RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16 1.0 none 1.0 0 3916012 1056183 0 1154668 1063517 0 948449 0 0 2217900 0 2979561 0 0 3431071 922552 0 0 750912 0 1225195 0 0 976517 0 0 0 771248 673972 824407 0 491604 0 0 0 0 759646 0 236860 156334 0 505906 257070 0 476279 0 0 829577 0 720162 0 0 412891 0 0 0 294426 0 114542 0 510247 347523 0 0 0 502820 374250 993895 0 0 0 0 0 0 175767 0 921841 351112 0 0 340439 0 576632 0 0 233945 0 801147 0 0 1209493 1071976 0 0 645531 0 512762 0 119768 397022 0 0 0 503675 505859 151487 0 500066 0 0 0 0 300890 0 770434 758336 0 1673974 776529 0 535164 0 0 2513765 0 2470953 0 0 4740363 935722 0 0 773117 0 1972194 0 1181900 855734 0 0 0 1717067 1203582 867352 0 835309 0 0 0 0 948499 0 113942 189134 0 0 75476 0 146245 0 0 646094 0 658495 0 0 299976 88677 0 0 0 0 0 0 0 205558 0 0 0 217728 0 323974 0 500776 0 0 0 0 243642 +AANEIIDAAGGDEAKPTGEN(Deamidated)GVYFAQAK MGYG000001306_00078;MGYG000001835_01971 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG3193@1|root,COG3193@2|Bacteria,4P0RZ@976|Bacteroidetes,2G0AC@200643|Bacteroidia,4AV3N@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_00078 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 525588 0 0 0 0 520308 0 0 0 0 565793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 639187 0 0 0 0 467995 0 0 0 0 526664 0 0 0 0 0 0 0 0 0 0 +AANELGYPVLVRPSYVLGGQGMR MGYG000000216_00641;MGYG000000142_00537;MGYG000001338_00548 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3WG9X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan 1.0 carB 1.0 - 1.0 6.3.5.5 1.0 ko:K01955 1.0 ko00240,ko00250,ko01100,map00240,map00250,map01100 1.0 M00051 1.0 R00256,R00575,R01395,R10948,R10949 1.0 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000216_00641 0.3333333333333333 carbamoyl-phosphate synthase (glutamine-hydrolyzing). glutamine-dependent carbamoyl phosphate synthetase. The product carbamoyl phosphate is an intermediate in the biosynthesis of arginine and the pyrimidine nucleotides.-!-The enzyme from Escherichia coli has three separate active sites, which are connected by a molecular tunnel that is almost 100 A in length.-!-The amidotransferase domain within the small subunit of the enzyme hydrolyzes glutamine to ammonia via a thioester intermediate.-!-The ammonia migrates through the interior of the protein, where it reacts with carboxyphosphate to produce the carbamate intermediate.-!-The carboxyphosphate intermediate is formed by the phosphorylation of hydrogencarbonate by ATP at a site contained within the N-terminal half of the large subunit.-!-The carbamate intermediate is transported through the interior of the protein to a second site within the C-terminal half of the large subunit, where it is phosphorylated by another ATP to yield the final product, carbamoyl phosphate. cf. EC 6.3.4.16.-!-Formerly EC 2.7.2.9. 2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Pyrimidine metabolism|Alanine, aspartate and glutamate metabolism|Metabolic pathways 1.0 K01955:carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 978636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANEQQIK MGYG000000089_00234 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG1882@1|root,COG1882@2|Bacteria,1VBNT@1239|Firmicutes,24MR3@186801|Clostridia,27NYF@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 C 1.0 Glycine radical 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Gly_radical 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000089_00234 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 990772 0 0 0 0 1230642 0 0 0 0 870880 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 221941 0 0 0 0 385361 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 404144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANESFGYNEDEIVSSDIVGMR MGYG000000262_01195;MGYG000002517_01026;MGYG000002492_01379;MGYG000001652_01009;MGYG000000489_00503 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_01195 0.2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216475 0 0 0 0 0 0 0 0 0 0 0 0 167452 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585615 0 850135 908313 687939 0 765358 0 615014 0 0 638603 0 0 0 2291677 0 0 446828 429852 1485302 683303 0 0 0 1513797 0 0 793771 0 463992 0 0 626181 0 639679 0 0 0 0 0 253812 0 0 170023 0 163393 0 0 197167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 182538 0 0 0 0 129473 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANESGLW(Dioxidation)NVTVQLK MGYG000000243_01886;MGYG000002171_01694 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01886 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANESGLWNVTVQLK MGYG000000243_01886;MGYG000002171_01694 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1196@1|root,COG1256@1|root,COG1196@2|Bacteria,COG1256@2|Bacteria,4P3FF@976|Bacteroidetes,2G3FB@200643|Bacteroidia,4AQ56@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 DN 1.0 COG NOG14601 non supervised orthologous group 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_01886 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2370989 0 8444221 4475836 3143333 2045109 3627990 3168207 2469152 2152013 2733366 2327737 3386965 1640216 1768619 1900770 2581985 1006765 2118563 2095231 1976838 1639374 1725835 1556546 2271964 2465100 2909492 2238019 3007104 3338542 4708427 3525057 9504103 3429120 3003065 2977939 2499469 6576101 0 0 0 0 0 0 0 0 0 0 0 0 204481 0 171526 148376 0 0 0 0 0 0 0 367976 0 0 0 0 0 0 162264 277551 0 0 0 60411 0 0 1816225 0 529718 1130226 795659 383090 778909 1206161 484634 1198877 598851 989164 1668414 777120 2017039 1336266 1383308 1381201 2127515 1594504 1091153 1160081 1458258 746776 948800 1917211 2059225 2422922 872763 1475867 530540 1222287 1653732 1298133 2650786 1024481 1455551 638813 65083 0 76178 72291 72005 170600 70010 482908 58965 81224 211897 0 59219 460756 388541 123250 85035 0 435963 170838 92252 0 0 93869 139868 0 512379 0 315713 161009 292601 268924 71838 0 0 364428 466932 150323 0 0 116865 102041 0 0 0 0 0 0 0 0 0 0 100103 0 150937 0 0 0 0 0 0 130356 0 0 121025 0 0 0 0 49871 211870 0 0 0 0 0 +AANEVEEDR MGYG000000044_01042;MGYG000000174_02677 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000044_01042 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 558254 0 0 393545 0 0 0 0 799264 0 1252674 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1277880 867590 0 454154 1314306 0 0 0 167731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1438368 1024973 0 1218256 0 0 0 0 865634 0 1056955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 991859 2008422 0 1083551 1681274 0 0 0 1272602 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANEVEEDRAFLIESNVEPK MGYG000000044_01042 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides merdae|m__MGYG000000044 1.0 2DUTV@1|root,33S7W@2|Bacteria,4P1VI@976|Bacteroidetes,2FWJJ@200643|Bacteroidia,22ZT0@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000044_01042 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 2619191 0 0 0 3382020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2846260 0 0 0 2915843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 295398 0 0 0 206844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399602 0 0 0 0 0 0 0 0 0 0 0 261834 0 0 0 321838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 634218 0 0 0 301247 0 0 0 0 +AANFEEVC(Carbamidomethyl)LGYNQEEAQAEAQR MGYG000000179_04744 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,21Y4Z@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 glutamate synthase (NADPH), homotetrameric 1.0 gltA 1.0 - 1.0 1.4.1.13,1.4.1.14 1.0 ko:K00266 1.0 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 1.0 - 1.0 R00093,R00114,R00248 1.0 RC00006,RC00010,RC02799 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHODB_Fe-S_bind,Fer4_20,NAD_binding_1,NAD_binding_8,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_04744 1.0 glutamate synthase (NADPH). | glutamate synthase (NADH). NADPH-glutamate synthase. | NADH-glutamate synthase. The reaction takes place in the opposite direction.-!-The protein is composed of two subunits, alpha and beta.-!-The alpha subunit is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.4).-!-The beta subunit transfers electrons from the cosubstrate.-!-The NH3 is channeled through a 31 A channel in the active protein.-!-In the absence of the beta subunit, coupling between the two domains of the alpha subunit is compromised and some ammonium can be produced.-!-In the intact alphabeta complex, ammonia production only takes place as part of the overall reaction.-!-Formerly EC 2.6.1.53. | A flavoprotein (FMN).-!-The reaction takes place in the direction of L-glutamate production.-!-The protein is composed of two domains, one hydrolyzing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2). 2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH. | 2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH. 1.0 1.0 1.0 1.0 Alanine, aspartate and glutamate metabolism|Nitrogen metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K00266:gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216355 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 561327 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507641 0 0 0 0 0 0 0 0 0 0 477406 0 +AANGN(Deamidated)MILVDKIAADEYK MGYG000003921_00344 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_00344 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 191004 0 0 0 0 346929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 197480 0 0 0 0 330776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 633024 0 0 0 0 736908 0 0 0 0 1071142 0 0 0 0 0 0 0 0 0 0 +AANGN(Deamidated)MVVVDK MGYG000001300_02214;MGYG000003899_00615;MGYG000003166_00760 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02214 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANGN(Deamidated)MVVVDKFAC(Carbamidomethyl)DEYK MGYG000001300_02214;MGYG000001255_02070;MGYG000003899_00615;MGYG000002545_01139;MGYG000002040_00971;MGYG000003166_00760 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02214 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 334888 472559 355893 592870 0 223587 0 85994 259063 0 380472 0 0 0 0 288443 0 0 0 0 0 145378 0 389331 0 306455 0 0 0 0 263798 104236 451550 513663 0 0 278186 402639 1270173 831935 1139386 1401544 695074 1145193 0 900089 1354675 0 697808 0 0 0 0 1162194 0 0 0 0 0 1293879 0 1121750 0 1369341 0 0 0 0 866883 1073612 1228763 1313531 0 0 1413171 1056542 352301 0 333391 141003 481293 322578 0 269951 211700 0 321289 0 0 0 0 277818 0 0 0 0 0 235231 0 435209 0 357896 0 0 0 0 184575 185660 0 407684 0 0 260517 304125 85940 239482 483090 297651 401274 237693 0 0 220764 0 319905 0 0 0 0 364558 0 0 0 0 0 252360 0 366761 0 329626 0 0 0 0 208510 116475 201160 537706 0 0 287768 277890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANGN(Deamidated)MVVVDKFTC(Carbamidomethyl)DEYK MGYG000000022_02039 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_02039 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 312276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 943669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANGNMILVDKIAADEYK MGYG000003921_00344 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540595|m__MGYG000003921 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_00344 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 443563 0 0 0 0 631207 0 0 0 0 650630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 327683 0 0 0 0 366317 0 0 0 0 236634 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 653275 0 0 0 0 619159 0 0 0 0 683156 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581509 0 0 0 0 689517 0 0 0 0 880687 0 0 0 0 0 0 0 0 0 0 +AANGNMVVVDKFAC(Carbamidomethyl)DEYK MGYG000001300_02214;MGYG000001255_02070;MGYG000003899_00615;MGYG000002545_01139;MGYG000002040_00971;MGYG000003166_00760 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3WGQT@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02214 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 660701 0 0 0 934085 0 941232 0 0 0 0 0 0 0 403178 0 717150 0 0 0 0 0 0 0 0 0 0 0 0 0 443571 0 0 0 0 529799 0 0 1170293 0 0 0 1367120 0 1148242 0 0 0 0 0 0 0 1320664 0 1229666 0 0 0 0 0 0 0 0 0 0 0 0 0 978714 0 0 0 0 926603 0 0 436106 0 0 0 641601 0 361824 0 0 0 0 0 0 0 363976 0 299806 0 0 0 0 0 0 0 0 0 0 0 0 0 278561 0 0 0 0 534573 0 0 546048 0 0 0 746881 0 503012 0 0 0 0 0 0 0 585339 0 364805 0 0 0 0 0 0 0 0 0 0 0 0 0 498035 0 0 0 0 473830 0 0 583631 0 0 0 431099 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 126976 0 0 0 0 0 +AANGSYYMANK MGYG000000133_00731 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1376@1|root,COG5263@1|root,COG1376@2|Bacteria,COG5263@2|Bacteria,1UVCF@1239|Firmicutes,24BKI@186801|Clostridia,3XZR4@572511|Blautia 1.0 186801|Clostridia 1.0 S 1.0 L,D-transpeptidase catalytic domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1,YkuD 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00731 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1159240 0 271802 1147739 0 1048553 0 0 462360 1227318 0 0 1357065 1088375 0 697879 1008321 0 0 1889536 0 934325 0 668739 0 1502647 919210 0 1143847 0 1186813 705529 827374 871764 0 1448747 1342163 1318384 +AANGVFDDANVQNR MGYG000002506_01355 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG3443@1|root,COG3443@2|Bacteria,1MXFK@1224|Proteobacteria,1RPWU@1236|Gammaproteobacteria,3XN2U@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 S 1.0 May function as a periplasmic zinc chaperone or mediate direct transport of zinc from the periplasm to the cytoplasm under zinc-limited conditions. Binds zinc with high affinity, and can also bind cadmium, mercury or nickel. Preferentially binds Zn(2 ) over Cd(2 ). Contains one high affinity metal binding site, and can bind additional metal ions at other sites 1.0 zinT 1.0 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0007154,GO:0008150,GO:0008270,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0030288,GO:0030313,GO:0031667,GO:0031668,GO:0031669,GO:0031975,GO:0033554,GO:0034224,GO:0042221,GO:0042594,GO:0042597,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046686,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0120127 1.0 - 1.0 ko:K09815 1.0 ko02010,map02010 1.0 M00242 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.15.3,3.A.1.15.5 1.0 - 1.0 - 1.0 ZinT 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_01355 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K09815:znuA; zinc transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1657773 1399452 1069103 0 1074417 2663627 1601993 1519149 1377066 2068008 0 1585851 0 1203247 1606825 0 1416663 0 0 0 1391955 2428344 0 2260729 1936430 1494453 1192368 0 1373230 1396640 0 1940437 994955 1655068 2056262 1395820 1082005 776255 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302079 0 0 0 0 +AANGVIIITTK MGYG000001787_01504;MGYG000002478_00526;MGYG000000196_04885;MGYG000002438_03064;MGYG000002438_02925;MGYG000003697_01696;MGYG000003697_02942;MGYG000000243_02417;MGYG000000013_00116 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 0.3333333333333333 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.8888888888888888 - 1.0 - 1.0 - 1.0 - 0.8888888888888888 MGYG000001787_01504 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1665743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1991136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385196 0 0 0 0 0 0 0 1687859 0 0 0 0 0 219588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1258695 0 0 0 0 0 0 0 0 0 0 0 0 0 1154130 0 0 0 0 744637 0 0 0 0 0 0 0 0 1227435 0 0 0 0 0 0 6520168 0 0 0 0 0 1581694 543041 0 994216 0 +AANGVILITTK MGYG000002478_00836;MGYG000004748_01412;MGYG000003693_02459;MGYG000000013_01157;MGYG000002478_02338;MGYG000000196_04885;MGYG000002438_02656;MGYG000004703_01713;MGYG000002549_02801;MGYG000003697_01696;MGYG000003697_02942;MGYG000000105_01953;MGYG000001056_01040;MGYG000004899_00167;MGYG000003681_00932;MGYG000000224_02063;MGYG000001346_01792;MGYG000000174_02248;MGYG000001346_00980;MGYG000000029_03133;MGYG000000029_02281;MGYG000000003_01946;MGYG000003952_01841;MGYG000003693_01019;MGYG000001780_04788;MGYG000001378_04550;MGYG000002478_00526;MGYG000001661_01562;MGYG000000044_02806;MGYG000001661_00232;MGYG000001661_01167;MGYG000001306_00226;MGYG000002560_03505;MGYG000001345_04118;MGYG000003351_02635;MGYG000000196_04852;MGYG000001780_00424;MGYG000003367_00988;MGYG000000236_00670;MGYG000001489_01819;MGYG000000243_02417;MGYG000001783_00138;MGYG000000105_02058;MGYG000000781_02387;MGYG000003362_01220;MGYG000002455_01534;MGYG000002549_04362;MGYG000001789_02404;MGYG000003812_00487;MGYG000002293_00753;MGYG000001789_00624;MGYG000004797_01501;MGYG000002281_03192;MGYG000001489_03122;MGYG000000138_01670;MGYG000000044_02057;MGYG000001787_01504;MGYG000004876_00069;MGYG000002935_01014;MGYG000001345_03656;MGYG000000236_04565;MGYG000002478_02514;MGYG000002614_00404;MGYG000001056_00294;MGYG000004876_02160;MGYG000004006_01269;MGYG000003681_01449;MGYG000001666_00819;MGYG000004899_00413;MGYG000001378_02713;MGYG000001925_02044;MGYG000003493_02393;MGYG000000013_00116;MGYG000001503_01401;MGYG000004797_02606;MGYG000000138_01202;MGYG000001337_00935;MGYG000002438_02925;MGYG000001783_00512;MGYG000000224_00522;MGYG000003701_02338;MGYG000001599_02769;MGYG000000196_01084;MGYG000003681_02804;MGYG000002478_01281;MGYG000000105_01199;MGYG000001346_02872;MGYG000003363_00305;MGYG000001789_01698;MGYG000004899_00346;MGYG000004830_01626;MGYG000002438_03064;MGYG000002834_00630;MGYG000002614_01804;MGYG000004758_01030 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.12631578947368421 976|Bacteroidetes 1.0 P 0.9894736842105263 TonB-linked outer membrane protein, SusC RagA family 0.8315789473684211 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.5157894736842106 - 1.0 - 1.0 - 1.0 - 0.8526315789473684 MGYG000002478_00836 0.010526315789473684 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2101002 1728761 2454030 2674743 1711009 2030971 2350468 1259865 2179580 1774597 0 1971712 0 2382763 1608791 1922945 2568007 1305085 1581053 1808257 1774273 2193491 0 2660441 1687397 2354328 2285861 0 1733911 1903136 2955435 1654441 2720715 0 1855405 2387248 2142263 2558526 777614 2109155 0 0 0 0 0 1257235 4462487 1010045 0 877316 0 0 0 2061024 0 3334041 0 0 0 0 4678809 0 0 0 2868591 3159685 619931 2493587 2571978 1298977 0 0 1511014 3525779 4008851 0 0 815655 1029001 1408252 1699066 0 0 818244 1417298 799508 1439249 1755147 676916 1123211 1032154 0 971090 0 761422 813880 1188672 998242 0 1875034 1088844 1155044 712186 2293586 1236858 921689 1934911 1008647 1141211 862598 869560 0 1307043 1349679 1070902 0 1432751 1162294 1300785 1139157 1256045 1159384 1275330 961156 790623 1417277 1142494 899533 1014082 680079 952507 1115247 1044864 954419 2522190 985092 2198024 355581 1045780 1262333 1097245 404233 599080 1185254 0 1860476 860454 1285251 1043644 1336789 1039685 809652 1381086 986448 1038465 1391225 1471503 1311434 1128966 1357919 1218122 701205 1481767 999379 1169159 888412 1101618 1421761 1120322 0 1255591 1811204 578933 1303379 3781541 778660 1140543 1002385 904925 0 1255620 1247224 1337152 864066 540064 0 1099102 384645 1015538 1466747 +AANGVILVTTK MGYG000000243_03100;MGYG000002478_00972;MGYG000004876_00726;MGYG000002478_00682;MGYG000001346_02823 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2FW4E@200643|Bacteroidia 0.2 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6 - 1.0 - 1.0 - 1.0 - 0.8 MGYG000000243_03100 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 545941 0 0 0 0 0 0 0 0 1322388 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 261678 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2481327 0 0 0 0 0 0 0 0 0 0 +AANGVIMVTTKR MGYG000002438_02926 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,22ZXY@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02926 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1901310 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANGVIVITTK MGYG000004658_01775;MGYG000003152_00999;MGYG000000138_00500;MGYG000000236_03672;MGYG000004763_02090;MGYG000000183_00749;MGYG000004899_00261;MGYG000000183_02215;MGYG000001337_01441;MGYG000000273_01469;MGYG000000215_02004;MGYG000000243_03324;MGYG000001789_02910;MGYG000000168_01320;MGYG000000236_01565;MGYG000001666_00513;MGYG000002561_00966;MGYG000004748_03723;MGYG000001643_01406;MGYG000002478_01932;MGYG000001787_00685;MGYG000004797_01619;MGYG000001552_01556;MGYG000001925_01391;MGYG000004658_01327;MGYG000003374_00894;MGYG000001346_02589;MGYG000001337_01168;MGYG000001489_02092;MGYG000004797_04210;MGYG000001835_00475;MGYG000000183_02645;MGYG000003681_00349;MGYG000004876_03094;MGYG000001337_01171;MGYG000002203_00896;MGYG000002051_00947;MGYG000000168_02423;MGYG000000183_02880;MGYG000002478_02355;MGYG000000074_02074;MGYG000004468_01877;MGYG000004479_02279;MGYG000002933_00766;MGYG000001562_02517 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2G3FU@200643|Bacteroidia,4AV1P@815|Bacteroidaceae 0.2 976|Bacteroidetes 0.9777777777777777 P 0.9111111111111111 TonB-linked outer membrane protein, SusC RagA family 0.7777777777777778 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.4444444444444444 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004658_01775 0.022222222222222223 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2361123 2052075 5379367 3121514 4200389 2709582 3387752 1648199 2563149 0 2091019 0 4443303 0 1741607 3335087 2572267 1752572 1546460 1791495 2712507 0 2369998 3854824 1853778 2388487 0 2238033 3046646 0 6171080 2372215 5742365 2202568 2668510 0 2996989 6791554 624300 282904 387402 920687 511247 288990 336722 352181 0 519578 495985 453235 706412 392695 401188 696234 359903 381712 434914 457567 173045 328016 640351 160529 391914 349708 341404 373325 308123 318021 405224 267229 399299 315230 502406 576771 368234 418105 1117322 394877 1153090 1183429 2013554 1495348 1593692 0 1706992 945330 1283312 926563 1948465 1290459 0 1903134 898537 2102751 895691 933920 973450 799411 1634831 1833504 0 1090139 0 0 1227126 1218716 1605905 737862 736189 900810 1035707 1553657 1203806 0 701003 540409 458109 698645 389067 0 754692 633193 451699 753941 446881 524670 742115 530597 721905 482127 528497 398343 490270 557547 568933 277703 0 0 748828 730001 636582 0 523828 605871 0 515917 242526 909554 698965 886118 580609 0 1994302 1371669 1276942 1751645 2679067 1981125 1460706 2251971 1822751 980222 851205 958286 3108074 1084010 1458256 2554832 1665598 0 1877467 3015227 1043506 2070517 0 1718019 1414065 1200804 1335975 0 2005315 1871945 1656603 1495755 851303 0 1872190 1483519 1545226 1370921 +AANGVIVLTTK MGYG000002478_01932;MGYG000000183_00749;MGYG000004763_02090;MGYG000001337_01168;MGYG000000183_02215;MGYG000001337_01441;MGYG000000183_02645;MGYG000001835_00475;MGYG000000243_03324;MGYG000001789_02910;MGYG000001337_01171;MGYG000000168_02147;MGYG000000168_02423;MGYG000000183_02880;MGYG000000168_01320;MGYG000002561_00966 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG4771@2|Bacteria,4P1Z5@976|Bacteroidetes,2G3FU@200643|Bacteroidia,4AV1P@815|Bacteroidaceae 0.1875 976|Bacteroidetes 0.9375 P 0.875 TonB-linked outer membrane protein, SusC RagA family 0.6875 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 0.5625 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01932 0.0625 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 2623393 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3213897 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1246427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANGVIYIT(Thr->Asn)TK MGYG000004885_01473;MGYG000003460_00312;MGYG000000243_03196 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,1WDNI@1283313|Alloprevotella 0.6666666666666666 976|Bacteroidetes 1.0 P 1.0 Carboxypeptidase regulatory-like domain 0.6666666666666666 ragA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004885_01473 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238760 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1353486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1002552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 880302 0 0 0 0 0 0 0 0 0 +AANGVIYVQTK MGYG000001302.1_00590 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 ragA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_00590 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 440451 0 635959 633069 877448 0 0 0 0 0 0 0 0 0 0 722020 984068 0 0 357401 862926 827711 0 0 0 651683 0 0 0 0 512855 0 0 0 0 602466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 967592 0 1141039 867145 982199 0 0 0 0 0 0 0 0 0 0 1614756 1024404 0 0 631101 1693735 999268 0 0 0 684022 0 0 0 0 568802 0 0 0 0 833949 0 0 0 0 0 0 258250 0 0 0 0 0 0 0 0 0 0 521911 504412 0 0 0 343129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 627965 0 807839 0 725204 0 0 0 0 0 0 0 0 0 0 2063030 1016798 0 0 484081 1805865 751520 0 0 0 1779289 0 0 0 0 423349 0 0 0 0 599829 +AANGVLLITTK MGYG000004797_02606;MGYG000001489_00601;MGYG000001489_00865;MGYG000001780_04788;MGYG000000196_04885;MGYG000002438_02925;MGYG000004899_01078;MGYG000000243_02417;MGYG000001783_00138;MGYG000001783_00512;MGYG000001925_01678;MGYG000004899_02902;MGYG000001925_00504;MGYG000001925_02673;MGYG000002834_00630;MGYG000002293_00753;MGYG000004797_01501 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.17647058823529413 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 0.8823529411764706 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.5294117647058824 - 1.0 - 1.0 - 1.0 - 0.7647058823529411 MGYG000004797_02606 0.058823529411764705 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1799813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1302235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407014 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANGVVFVTTK MGYG000000074_01126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01126 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2323325 0 1367153 0 1048102 0 0 1336197 0 2014095 1005705 1515271 0 0 1855132 887325 0 0 0 2025730 1307484 0 0 0 1414331 1472914 1674708 0 1273993 1572824 0 0 1006852 1556197 1745421 0 1784729 1107935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 259701 0 0 0 0 0 0 264594 0 0 0 0 0 0 229696 0 0 0 0 0 271335 0 0 0 291221 473350 214547 0 0 0 0 0 0 0 366985 0 354600 0 867885 0 442550 0 369446 0 0 199420 0 799181 0 357477 0 0 657459 363947 0 0 0 623256 221358 0 0 0 590827 419684 637771 0 1073729 295454 0 0 595250 330882 292386 0 314689 257437 +AANGVVIITTK MGYG000000042_01138;MGYG000002478_01456;MGYG000004876_03105 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG4772@1|root,COG4772@2|Bacteria,4PM03@976|Bacteroidetes,2G09Q@200643|Bacteroidia,4AV6D@815|Bacteroidaceae 0.6666666666666666 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000042_01138 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1413305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 945134 0 0 0 0 0 0 0 0 0 0 1285124 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 690791 0 0 0 0 0 0 0 0 0 0 0 0 270445 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANGVVLITTK MGYG000002438_02058;MGYG000003697_00063;MGYG000001306_00077;MGYG000002438_00500;MGYG000002478_01456;MGYG000002960_00789;MGYG000002455_02640;MGYG000001780_01166;MGYG000000781_01695;MGYG000004876_02091;MGYG000003697_02396;MGYG000004797_02570;MGYG000001346_03464;MGYG000004899_00028;MGYG000000243_03191;MGYG000000196_00609;MGYG000002834_00176;MGYG000002478_02188;MGYG000004876_01524;MGYG000001643_02196;MGYG000001835_01972;MGYG000002171_01681;MGYG000004876_03105;MGYG000001643_01263 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,4AK5Y@815|Bacteroidaceae 0.20833333333333334 976|Bacteroidetes 1.0 P 0.9166666666666666 TonB-linked outer membrane protein, SusC RagA family 0.7083333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 0.9166666666666666 MGYG000002438_02058 0.041666666666666664 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 157811 0 175452 0 0 270172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208837 179626 0 0 0 195150 0 154113 0 106451 0 219859 148659 0 0 0 264227 214224 635967 0 704421 0 0 323381 0 546535 0 0 447189 0 0 0 0 545169 0 0 0 0 1094027 589702 1924133 337171 0 143570 0 0 0 448806 0 435250 459106 0 0 0 710640 502753 654127 0 778106 0 0 981208 0 181887 0 0 906478 0 0 0 0 0 0 0 0 0 868661 0 0 822434 0 713114 0 532522 0 0 0 175487 499795 0 0 0 753220 0 0 0 1494894 0 0 666210 0 0 0 0 923577 0 0 0 0 0 0 612827 0 0 333695 960632 738318 870328 0 420670 0 0 0 0 0 502819 1057242 0 0 0 0 1090157 154672 0 708272 0 0 410199 0 438279 0 0 0 0 0 0 0 407259 0 2260507 0 0 0 412627 2235725 0 0 256493 0 3080153 0 927616 0 397291 0 0 0 0 172409 257927 +AANGVVMITTK MGYG000002478_01935;MGYG000000781_01691 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_01935 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2017165 0 0 2116268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 519391 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361698 0 334915 0 0 449207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328726 0 +AANIAANK MGYG000000003_01531 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes shahii|m__MGYG000000003 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,22V2J@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000003_01531 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 208451 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANIIGIQIEFAK MGYG000002506_02942;MGYG000002494_02450;MGYG000002515_03184;MGYG000002323_00405;MGYG000002366_00455;MGYG000002534_00411;MGYG000002535_04680;MGYG000002477_00168 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0200@1|root,COG0200@2|Bacteria,1RDC8@1224|Proteobacteria,1S3P6@1236|Gammaproteobacteria,3XPK7@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Binds to the 23S rRNA 1.0 rplO 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02876 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L27A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02942 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02876:RP-L15, MRPL15, rplO; large subunit ribosomal protein L15 1.0 none 1.0 793675 799249 873704 765884 546869 818637 1057538 1232530 991615 937828 484117 784398 248730 896947 655584 229911 744715 0 655273 761017 719535 1080823 0 1093084 754985 841470 883162 0 1022030 1232874 825201 989511 807812 848600 1183339 940639 952468 634915 1584045 1378223 1442731 1364097 1475734 3240894 2052083 1872040 1755313 2080486 871941 1904523 859732 1608294 2140047 1597567 2592118 0 1570927 1579209 2053455 4638962 0 2876382 1958839 1833104 1686323 0 2317325 1629706 945244 1799065 1300430 1576862 1704992 1557852 1563675 1418126 884677 822717 614358 348017 1125869 2151019 1128996 1239256 560847 1110688 850202 1056945 835578 1028911 805289 1198677 950627 0 872353 962750 1129057 1460703 0 2423565 1059966 763525 869933 0 816741 795628 1039713 811313 908765 1034379 1013661 791623 629189 957054 855035 673761 776135 612533 510947 896649 1075957 920238 568852 922872 430746 749994 558522 525573 594627 520989 618429 0 777455 539336 922256 707993 0 710941 754363 748926 908552 0 401921 621953 280542 610366 525602 1018027 1071680 781597 665446 287661 0 3992206 0 3252006 2851990 4521526 2127515 0 2734864 0 28041241 0 5311486 0 0 2170623 0 0 1937778 5747747 0 1288431 0 0 2040290 3921906 1809540 0 16513 2240381 0 0 2480973 3400071 0 15522 5473473 0 +AANIIVKDEK MGYG000003372_00011;MGYG000002477_01208;MGYG000002535_03830;MGYG000002515_04070;MGYG000002494_02687;MGYG000002323_03813;MGYG000002506_03877 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG3029@1|root,COG3029@2|Bacteria,1RD34@1224|Proteobacteria,1S419@1236|Gammaproteobacteria,3XPS9@561|Escherichia 0.5714285714285714 1236|Gammaproteobacteria 1.0 C 1.0 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane 1.0 frdC 1.0 GO:0000104,GO:0001539,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006996,GO:0008150,GO:0008152,GO:0008177,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016635,GO:0022607,GO:0030030,GO:0030031,GO:0032991,GO:0040011,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048870,GO:0051179,GO:0051674,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071973,GO:0097588,GO:0098796,GO:0098797,GO:0098803 1.0 - 1.0 ko:K00246 1.0 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 1.0 M00009,M00011,M00150,M00173 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002 1.0 - 1.0 - 1.0 iYL1228.KPN_04551 1.0 Fumarate_red_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003372_00011 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Two-component system 1.0 K00246:frdC; succinate dehydrogenase subunit C 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 898975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1076476 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1798119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 423919 0 0 0 992591 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANIMLDAGAK MGYG000001378_00980 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EF 1.0 COG0462 Phosphoribosylpyrophosphate synthetase 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_00980 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00948:PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 2144811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 296950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANIMLEAGAK MGYG000001346_00360;MGYG000002549_01851;MGYG000004876_02520 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EF 1.0 COG0462 Phosphoribosylpyrophosphate synthetase 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_00360 0.3333333333333333 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00948:PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 1.0 none 1.0 0 0 0 0 0 0 0 236619 0 0 0 0 0 690770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 543250 0 690099 0 0 995421 0 0 777930 0 0 0 0 0 0 0 471448 0 1960374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308781 0 592103 0 0 0 0 0 664496 0 0 0 0 0 0 0 355650 0 758774 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517548 0 373710 0 0 565282 0 0 306262 0 0 0 0 0 0 0 338596 0 430549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247203 0 179206 0 0 1394154 0 0 14726981 0 0 0 0 0 0 0 152527 0 519439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANIMMEAGAK MGYG000002281_04553;MGYG000000196_02130 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,4AN3Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EF 1.0 COG0462 Phosphoribosylpyrophosphate synthetase 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_04553 0.5 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00948:PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 1.0 none 1.0 0 0 296015 663483 0 265114 0 0 0 0 0 0 0 419580 0 0 0 0 0 0 0 323639 0 341945 0 0 0 0 0 0 0 0 0 0 0 0 0 174939 0 0 551770 620696 493911 486844 0 563783 0 0 0 0 0 712292 0 0 0 0 0 0 0 499119 0 287986 0 0 0 0 0 0 0 0 222595 0 0 0 0 464434 0 0 576298 534761 607206 562440 0 423390 0 0 0 0 0 754336 0 0 0 0 0 0 0 322080 0 565046 0 0 0 0 0 0 0 0 329380 0 0 0 0 433997 0 0 355937 0 174431 0 0 0 0 0 0 0 0 568226 0 0 0 0 0 0 0 0 0 301594 0 0 0 0 0 0 0 0 0 0 0 0 0 480448 0 0 0 298927 0 259035 0 330479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANINK MGYG000001564_01347 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster clostridioformis_A|m__MGYG000001564 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,2207S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001564_01347 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2104130 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANKFPAIIYGGA(Ala->Lys) MGYG000002494_03782 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 L 1.0 Type III restriction protein res subunit 1.0 yejH 1.0 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 1.0 - 1.0 ko:K19789 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03400 1.0 - 1.0 - 1.0 - 1.0 Helicase_C,ResIII 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03782 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K19789:radD; DNA repair protein RadD 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 380873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 422410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANKFPAIIYGGAEAPI MGYG000002494_03782;MGYG000003372_02072 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1061@1|root,COG1061@2|Bacteria,1MV9F@1224|Proteobacteria,1RNAN@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 L 1.0 Type III restriction protein res subunit 1.0 yejH 1.0 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042221,GO:0042493,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051301,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 1.0 - 1.0 ko:K19789 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03400 1.0 - 1.0 - 1.0 - 1.0 Helicase_C,ResIII 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03782 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K19789:radD; DNA repair protein RadD 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANKFPAIIYGGK MGYG000002323_02760;MGYG000002506_01672 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG1825@1|root,COG1825@2|Bacteria,1RDH0@1224|Proteobacteria,1S46A@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance 1.0 rplY 1.0 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 1.0 - 1.0 ko:K02897 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L25p 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_02760 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02897:RP-L25, rplY; large subunit ribosomal protein L25 1.0 none 1.0 279210 0 246284 352832 178860 463482 466793 222726 0 378436 75155 252866 161968 170916 347689 84534 208823 0 224567 194108 436865 530723 0 829326 0 314093 375766 0 453509 381142 184137 0 337386 212372 476583 344917 274439 251807 418596 0 465864 396563 405551 623871 301516 514900 0 665732 408818 431635 139980 496199 513451 414650 403766 0 514673 482638 525645 831700 0 694076 0 482022 443946 0 0 538715 364650 0 356906 411123 577577 446857 553840 559375 367612 0 617839 111652 745649 1133629 461454 440538 0 356895 526356 652756 361337 574543 361815 713350 392440 0 317335 483479 714436 973657 0 1310672 0 71226 310644 0 618860 533778 389619 0 474137 447982 354901 461217 105084 611335 0 0 0 0 0 0 0 86786 0 0 0 0 0 0 0 0 0 0 0 76230 330720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84455 91936 60484 0 0 0 0 0 0 148991 0 0 164752 122403 0 102746 0 0 0 0 0 0 166636 0 0 0 0 0 0 57376 0 0 0 75621 0 +AANKGEDDKVSTALAR MGYG000000198_01214 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,21YVN@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 J 1.0 elongation factor G 1.0 fusA2 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_01214 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 751965 0 0 0 0 0 224009 0 344516 0 0 0 0 523726 0 0 0 0 0 0 0 0 0 0 0 388490 0 0 466722 0 0 0 0 0 637238 0 385985 0 229579 0 0 0 0 0 174225 0 0 0 0 0 0 292053 0 0 0 0 0 0 0 0 0 0 0 101803 0 0 233304 0 0 0 0 0 373858 0 319738 0 1071340 0 0 0 0 0 786187 0 820778 0 0 0 0 875201 0 0 0 0 0 0 0 0 0 0 0 311996 0 0 932167 0 0 0 0 0 455127 0 286752 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238247 0 0 0 0 0 420978 0 318971 0 0 0 0 559641 0 0 0 0 0 0 0 0 0 0 0 500732 0 0 38252 0 0 0 0 0 0 0 222021 0 +AANKPDAIKEK MGYG000003937_00036 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 - 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS,UBA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003937_00036 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 550289 690688 0 0 0 0 0 0 0 723643 990503 0 834801 0 0 903309 999833 1617993 0 1079947 780196 0 0 0 756333 556000 0 1280746 694961 0 0 0 0 0 621991 0 684420 0 0 0 0 0 0 0 0 0 0 0 0 0 39082 0 0 0 0 0 0 56578 32247 0 0 0 0 0 0 0 34256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41569 0 0 58187 0 0 0 0 0 0 55967 0 0 0 0 145598 0 0 0 0 0 0 0 0 0 0 154587 191374 0 0 0 0 0 0 0 132925 183865 0 259261 0 0 332858 158702 345894 0 196650 0 0 93147 0 117454 125409 0 572341 105445 0 0 0 0 0 106840 0 153003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 33334 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANKYAGTQTEK MGYG000000212_01587;MGYG000000251_01537;MGYG000000154_01425;MGYG000000193_03705;MGYG000000067_02301;MGYG000001319_01032 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1592@1|root,COG1853@1|root,COG1592@2|Bacteria,COG1853@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF2201_N,Fer4_6,Flavin_Reduct,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01587 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 819592 0 0 0 0 0 0 1098628 0 0 0 0 888571 0 0 0 0 513247 0 424122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103582 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 266889 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157635 0 0 0 0 0 0 0 0 0 222823 0 44003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANKYAGTQTEKNLQEAFAGESQAR MGYG000000212_01587;MGYG000000251_01537;MGYG000001319_01032 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1592@1|root,COG1853@1|root,COG1592@2|Bacteria,COG1853@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF2201_N,Fer4_6,Flavin_Reduct,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01587 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANLDAIHDTVHE(Dioxidation)MAR MGYG000000123_00688;MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000002278_00133;MGYG000000139_02333;MGYG000000274_00102;MGYG000000249_00436;MGYG000000245_00992;MGYG000002702_00869;MGYG000004785_01880;MGYG000000076_00982;MGYG000002517_02838;MGYG000001560_01146;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000004263_01270;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000002837_00277;MGYG000000208_01702;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000000909_00619;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000004697_00836;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.45 186801|Clostridia 0.975 C 1.0 Rubrerythrin 0.6 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.975 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000123_00688 0.025 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 944356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 819340 818595 0 0 0 1150059 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 290131 0 0 +AANLDAIHDTVHEM(Dioxidation)AR MGYG000000123_00688;MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000002278_00133;MGYG000000139_02333;MGYG000000274_00102;MGYG000000249_00436;MGYG000000245_00992;MGYG000002702_00869;MGYG000004785_01880;MGYG000000076_00982;MGYG000002517_02838;MGYG000001560_01146;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000004263_01270;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000002837_00277;MGYG000000208_01702;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000000909_00619;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000004697_00836;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.45 186801|Clostridia 0.975 C 1.0 Rubrerythrin 0.6 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.975 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000123_00688 0.025 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 462968 821616 0 467389 0 1052010 335847 746699 166542 0 0 0 0 0 0 0 0 0 0 0 0 1098524 0 490207 0 278489 0 0 0 0 0 0 0 703262 0 0 424599 0 872682 1302497 0 631766 0 447784 545033 562342 796021 0 0 0 0 0 0 0 0 0 0 0 0 241270 0 696640 0 680106 0 0 0 0 0 0 0 714650 0 0 641336 0 290934 790347 0 335142 0 371162 467999 484540 268417 0 0 0 0 0 0 0 0 0 0 0 0 891434 0 322845 0 256418 0 0 0 0 0 0 0 511191 0 0 463083 0 605520 685775 0 336532 0 0 597783 872825 430830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 370408 0 0 0 0 0 0 0 225113 0 0 257976 0 904878 763136 0 626188 0 774229 1264059 693504 935706 0 0 0 0 0 0 0 0 0 0 0 0 719389 0 701060 0 639142 0 0 0 0 0 0 0 1009555 0 0 170251 0 +AANLDAIHDTVHEM(Dioxidation)ARDEAR MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000000139_02333;MGYG000000249_00436;MGYG000000245_00992;MGYG000000076_00982;MGYG000002517_02838;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.4482758620689655 186801|Clostridia 0.9655172413793104 C 1.0 Rubrerythrin 0.6551724137931034 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.9655172413793104 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001456.1_00549 0.034482758620689655 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANLDAIHDTVHEM(Oxidation)AR MGYG000000123_00688;MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000002278_00133;MGYG000000139_02333;MGYG000000274_00102;MGYG000000249_00436;MGYG000000245_00992;MGYG000002702_00869;MGYG000004785_01880;MGYG000000076_00982;MGYG000002517_02838;MGYG000001560_01146;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000004263_01270;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000002837_00277;MGYG000000208_01702;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000000909_00619;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000004697_00836;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.45 186801|Clostridia 0.975 C 1.0 Rubrerythrin 0.6 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.975 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000123_00688 0.025 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2237682 2700922 1461812 1526979 2236209 2216673 1198192 1782990 1704138 2245814 1952980 1920704 2368711 1674902 2556426 2551169 2298923 5258386 1783623 2220370 1930557 3085885 2459673 1385407 1939182 1692592 1824631 2670385 2531337 2010120 1303944 1712938 1512123 1746811 1750031 1357355 1652177 1871627 2584562 4038136 1476761 1859936 1460326 1455241 1714703 2258954 2532743 1419352 1211232 1298599 1331215 1211150 1718787 1031089 2119686 5752538 1364230 1856487 1738177 930856 2943905 2259320 1206638 1458472 1488891 3399461 1951291 1129308 3720513 1692128 1235572 1894149 2551002 2117723 1923461 1603779 2419812 3916793 1190655 1498028 912135 1719479 1573528 2311610 1946504 1825933 1542945 1900496 1852727 1937457 2596081 2358652 1534747 1856445 2044436 1913546 2302954 3308556 3100753 1621249 1696886 2111200 2423041 3121473 2534337 2148652 1337692 2760559 1773616 1997246 1560822 1758427 1661956 1549091 1754035 2451735 1419803 1431806 1513180 1121295 1310231 1287581 1466158 1174600 1086053 1325565 1699169 1363025 1166521 1524338 1686680 1763520 1187659 2002707 1421887 1637953 820805 1381115 1259576 1639615 1453839 1033196 1311897 1416904 1736429 1734254 1662669 1004840 1401243 1664186 1180719 1716454 3997452 3529630 3404523 4560160 1274319 2340675 6103483 4152176 3225333 4386748 3453372 3225899 2129179 5337632 4460825 3547101 3573979 1355103 4355054 2212196 4764362 3236488 2880825 2994289 3898660 3390202 4144377 4485445 5776414 1890868 3270868 4055067 4189149 4331023 3724397 4360782 2489699 2626891 +AANLDAIHDTVHEM(Oxidation)ARDEAR MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000000139_02333;MGYG000000249_00436;MGYG000000245_00992;MGYG000000076_00982;MGYG000002517_02838;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.4482758620689655 186801|Clostridia 0.9655172413793104 C 1.0 Rubrerythrin 0.6551724137931034 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.9655172413793104 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001456.1_00549 0.034482758620689655 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1917888 3301756 2768635 1328549 2667240 2226337 1351871 2540929 462494 3042302 2082315 619963 2541757 1867528 2414963 1989920 2476600 3156142 0 1876455 2005545 2866776 412557 427136 2865661 1706003 401531 2119148 1905538 546053 348245 2640124 1756426 1446360 1608293 1156151 410129 1814359 256255 584128 0 212133 309527 423057 267875 338787 227981 291463 252976 0 351144 311025 253050 254499 151414 0 238118 189579 249311 291321 682400 252835 354340 279504 324426 746792 387595 105052 727375 380005 297949 558235 744507 98270 413386 304479 3562586 3431061 2205642 1600682 1053558 1719985 1938428 2266622 1665805 2158406 2273708 1445132 1750233 2638158 2745267 2600552 2493781 430266 3755284 2325790 1623819 2696557 1752809 1629154 3261840 2182525 2775688 1556441 2023388 3124142 1738463 2469914 3500323 2541965 1814478 1333314 2212276 1903943 770606 978975 1223761 1050656 896625 1031407 809029 989674 862723 1122637 617183 588291 969845 616444 824982 994957 977767 460104 843573 1408499 1499585 882596 998221 814078 1058427 945811 797887 1201720 1321309 697062 762551 734213 676387 555023 525621 1451723 937004 1423167 847181 1866234 2037725 2647384 928979 1406142 2000491 1769878 707140 2093884 1606773 1615484 1223782 1848542 1395724 911817 2663870 0 1454163 1335844 1887154 939874 441413 337872 1213935 1129713 1223350 1516018 1541723 762993 1747972 2324687 2680236 1169971 946442 1595570 645846 938117 +AANLDAIHDTVHEMAKDEAR MGYG000000359_01014 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__UBA7182|s__|m__MGYG000000359 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 1.0 186801|Clostridia 1.0 C 1.0 Rubrerythrin 1.0 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000359_01014 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 274829 0 0 0 0 0 0 0 0 0 0 302933 0 211556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 209218 0 0 0 0 0 0 0 0 0 0 208670 0 1052548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1232921 0 0 0 0 0 0 0 0 0 0 666912 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 151805 0 0 0 0 0 0 0 0 0 0 0 0 +AANLDAIHDTVHEMAR MGYG000000123_00688;MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000002278_00133;MGYG000000139_02333;MGYG000000274_00102;MGYG000000249_00436;MGYG000000245_00992;MGYG000002702_00869;MGYG000004785_01880;MGYG000000076_00982;MGYG000002517_02838;MGYG000001560_01146;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000004263_01270;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000002837_00277;MGYG000000208_01702;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000000909_00619;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000004697_00836;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.45 186801|Clostridia 0.975 C 1.0 Rubrerythrin 0.6 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.975 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000123_00688 0.025 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 5576112 5694172 3659892 3963177 4709512 5450761 3365725 4220654 3711099 4179236 4855220 4558187 4290140 3806742 5333016 4542061 4438495 8926898 3081023 4843847 5811381 6021736 7885800 4040208 4144401 3804367 5092821 7100210 5517388 4851193 3416108 5017498 3342489 4094392 4716991 4587595 4159158 4310643 2810255 6207714 1974453 2171990 2173549 1924602 2222817 2398005 1725698 2192543 1749593 1619897 1698288 1617553 2634028 1816602 2957713 8490225 1711247 1887218 2673440 1755525 4632646 3025456 1675522 1973091 2537131 5405461 2505763 2174118 4068749 2814319 1847467 2480493 2798343 2873008 1796524 2277610 5201348 4852097 3421808 3265929 2386241 3721506 4705657 4258151 3195097 4920034 2729279 5151946 3038298 4955196 6647112 3677902 4250026 4841309 5114291 4763665 4852600 5741163 7958430 3386139 4762996 5317570 5242488 9597818 5699569 5290128 3995157 5433730 4011455 5321019 5864103 4390789 5290704 3678137 1635816 3339344 1423788 1670609 2514968 1646064 1773751 1714583 1716350 1406590 1761593 1877055 2165121 2068665 1214813 1742685 2448519 4371979 1492658 2142194 2152599 1913017 3736275 2076638 1826200 1641382 1894049 3997549 2406970 1773992 2944217 2458348 2041651 1114686 1625181 1788749 1431103 2264990 11532554 11356787 6433684 14463179 3449369 5655705 12421202 7921468 6663209 10943945 8496174 8560975 4674063 10847524 9295816 8073110 9209342 4287495 11395956 6004974 12133821 7790208 7477667 8979955 7556161 6817444 9600519 10073127 16431483 4233275 7746341 11185839 9377196 10096575 6488277 7853954 5234601 5944520 +AANLDAIHDTVHEMARDEAR MGYG000001456.1_00549;MGYG000000133_01999;MGYG000000177_00118;MGYG000000038_01470;MGYG000000028_00081;MGYG000000194_01177;MGYG000000139_02333;MGYG000000249_00436;MGYG000000245_00992;MGYG000000076_00982;MGYG000002517_02838;MGYG000000389_01907;MGYG000001310_02359;MGYG000001617_03135;MGYG000001652_00102;MGYG000000201_02350;MGYG000000067_01199;MGYG000004691_00975;MGYG000002528_00902;MGYG000000002_03896;MGYG000000204_00486;MGYG000000378_01233;MGYG000001528_00867;MGYG000004317_02085;MGYG000002969_00706;MGYG000001338_03531;MGYG000004689_01089;MGYG000001315_00988;MGYG000003694_02267 domain d__Bacteria 1.0 COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,27V2Z@189330|Dorea 0.4482758620689655 186801|Clostridia 0.9655172413793104 C 1.0 Rubrerythrin 0.6551724137931034 rbr3A 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Rubredoxin,Rubrerythrin 0.9655172413793104 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001456.1_00549 0.034482758620689655 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1672022 2010937 3208173 1077303 2377429 2095355 924637 1901539 1290213 2347209 2302086 1792477 2260321 1944996 1546849 1328531 1461740 2188860 1561179 1275445 1454031 2295973 2662187 1019598 1645979 1239144 1206442 3274705 1567632 2081730 1774966 2363103 1655053 1139976 1769998 1039943 1069413 1796550 150919 297697 0 0 470371 181772 0 203361 0 276785 257732 0 194354 0 206095 209885 0 214886 0 96854 116277 219584 0 347327 0 0 67527 118345 412212 0 526826 329794 173267 147405 152005 0 56660 0 1913489 2533592 1706992 1299101 1073181 1549237 1451054 2075188 1018869 0 1214922 1807327 1642064 1535599 1818105 1864983 1665547 716577 1950778 2139351 1456733 1771831 1463533 1478646 2061664 2582701 1931238 1863449 1628016 2285568 1495880 1991384 1649252 2134332 2006717 1135639 1788526 1156323 113475 673143 408809 422528 582966 316733 265889 80689 69934 251147 335263 0 47782 86940 316421 90256 0 332178 54967 153878 846428 517031 1202658 284255 140927 0 259940 1465683 503517 0 370558 76822 234058 315156 268225 708673 52108 585213 729351 1777410 2382162 4271647 722602 1317513 1162387 926326 810128 2165245 2699518 1529727 1728243 1451682 1481541 581032 2512153 0 1223678 673794 1373239 414343 0 725127 636929 672643 1004595 127101 1658187 826731 1783822 3473131 2250190 729515 561867 1324490 773399 1253356 +AANLDPEFVK MGYG000001415_00933 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes communis|m__MGYG000001415 1.0 COG1390@1|root,COG1390@2|Bacteria,4NTEY@976|Bacteroidetes,2G2KK@200643|Bacteroidia,22UJC@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane 1.0 - 1.0 - 1.0 - 1.0 ko:K02121 1.0 ko00190,ko01100,map00190,map01100 1.0 M00159 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002 1.0 3.A.2.2,3.A.2.3 1.0 - 1.0 - 1.0 ATP-synt_B,vATP-synt_E 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001415_00933 1.0 - - - - 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Metabolic pathways 1.0 K02121:ATPVE, ntpE, atpE; V/A-type H+/Na+-transporting ATPase subunit E 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1060019 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 175754 0 0 0 0 0 0 0 0 0 +AANLER MGYG000000121_01611 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Eubacteriales|f__Eubacteriaceae|g__Eubacterium|s__Eubacterium callanderi|m__MGYG000000121 1.0 COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,25V9A@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 S 1.0 Endoribonuclease that initiates mRNA decay 1.0 rny 1.0 - 1.0 - 1.0 ko:K18682 1.0 ko03018,map03018 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko03019 1.0 - 1.0 - 1.0 - 1.0 DUF3552,HD,KH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000121_01611 1.0 - - - - 1.0 1.0 1.0 1.0 RNA degradation 1.0 K18682:rny; ribonucrease Y [EC:3.1.-.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANLMLENGAK MGYG000002438_00755 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0462@1|root,COG0462@2|Bacteria,4NEVF@976|Bacteroidetes,2FPH1@200643|Bacteroidia,22WNU@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) 1.0 prs 1.0 - 1.0 2.7.6.1 1.0 ko:K00948 1.0 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00005 1.0 R01049 1.0 RC00002,RC00078 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Pribosyl_synth,Pribosyltran_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00755 1.0 ribose-phosphate diphosphokinase. ribose-phosphate pyrophosphokinase. dATP can also act as donor. ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00948:PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1104847 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1120414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANLPEAMIENIAK MGYG000003693_02548 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_02548 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 487692 0 0 0 0 383914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3441730 0 0 0 0 5345514 0 0 0 0 3903795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANLPEQMIQNIAK MGYG000001489_01081;MGYG000000105_01496 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,22W7D@171551|Porphyromonadaceae 0.5 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001489_01081 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1914386 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1147837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 830194 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANLPQAMIEN(Deamidated)IAK MGYG000001783_00059;MGYG000000273_00241;MGYG000001306_01209 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001783_00059 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 328617 0 0 0 0 0 0 0 0 0 0 772592 0 0 1584150 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 665918 0 0 0 0 0 0 0 0 0 0 0 0 0 150117 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167318 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 163010 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANLPQAMIENIAK MGYG000001783_00059;MGYG000000273_00241;MGYG000001306_01209 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001783_00059 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877205 0 1202117 0 0 0 0 0 1967903 0 0 0 0 0 0 3542563 0 0 0 0 5024315 0 0 0 0 4012587 0 0 0 0 799949 0 0 0 0 563352 0 0 668489 0 432013 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANLPQQM(Oxidation)IENIAK MGYG000004797_01413;MGYG000003521_01644;MGYG000002438_01052;MGYG000002478_01739 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01413 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 877009 982862 0 0 0 0 0 0 1891578 0 0 1744180 2074666 0 0 0 838322 604748 0 789938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 714727 311878 0 0 0 0 0 0 731362 0 0 452700 300619 0 0 0 243099 399038 0 383824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 854689 829641 0 0 0 0 0 0 655311 0 0 813691 692869 0 0 0 335288 760121 0 610949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278875 397189 0 0 0 0 0 0 512628 0 0 392941 281491 0 0 0 372311 324597 0 255472 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1263092 1272379 0 0 0 0 0 0 1690414 0 0 734048 970574 0 0 0 665393 646108 0 1084801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANLPQQMIENIAK MGYG000004797_01413;MGYG000003521_01644;MGYG000002438_01052;MGYG000002478_01739 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia,4AM7D@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01413 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 4542577 4677374 5177608 4468329 6079889 3912216 6285145 3731370 5181481 4236023 3782936 5277330 11042101 3924997 3083058 7699305 4834839 3341391 3786636 4349924 4857148 3532293 4939537 5351580 3638768 4979459 5504437 5857090 5504319 5143391 7547620 5260981 4454925 2713352 4481623 6591185 4687451 4790455 5475843 4341660 4544695 5697744 10706211 5474240 5259924 6125779 3835553 6733666 7005638 6994791 21455142 6200246 7127953 13415177 6331660 4423669 6634071 6889203 8825596 6766957 6865475 5122109 5495079 6401016 7542925 6049588 6655989 6767909 4230425 6760319 5305137 3812915 4675481 4652729 4943724 3846700 2014606 2466655 3055155 1897439 4525779 3363310 3069432 2157468 2746741 0 2920942 3559311 4786265 2326222 1670510 4541417 2251452 4964304 1985405 1931556 2998283 2878303 4194129 3563204 1725489 2176421 1735441 3919143 3050887 2588713 3176780 2789842 2147707 1070273 2020510 2986793 2112991 2499442 1687772 1366825 1385095 1102436 1339227 1154926 0 1435752 1243474 1506967 1131957 1696860 1802690 1691878 1389721 1430617 1048019 348932 1315987 1254111 4009971 0 599185 792893 1703240 1821404 1460587 259762 980774 1784513 1067157 1625671 1168990 1614679 1869434 1903288 1580731 864292 5514947 4433873 4499385 6886509 13145385 7127387 5791122 7313573 7135853 4537727 5975938 7867703 16806912 5504562 4611345 11113439 7443014 10906551 5905034 8627025 8162660 7047378 11157281 6095634 6338937 7501137 5479027 11642177 7072663 11799936 5765439 8355174 4653101 7945623 8609911 6245279 9352517 6595706 +AANLTDF MGYG000002517_02338 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the enoyl-CoA hydratase isomerase family 1.0 crt 1.0 - 1.0 4.2.1.17 1.0 ko:K01715 1.0 ko00650,ko01200,map00650,map01200 1.0 - 1.0 R03026 1.0 RC00831 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 ECH_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_02338 1.0 enoyl-CoA hydratase. unsaturated acyl-CoA hydratase. Acts in the reverse direction.-!-With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74). (1) a 4-saturated-(3S)-3-hydroxyacyl-CoA = a (3E)-enoyl-CoA + H2O. (2) a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O. 1.0 1.0 1.0 1.0 Butanoate metabolism|Carbon metabolism 1.0 K01715:crt; enoyl-CoA hydratase [EC:4.2.1.17] 1.0 none 1.0 232670 0 0 0 0 91297 78984 50045 0 102413 0 0 0 113639 352839 0 377091 0 67369 56610 0 197144 0 0 121766 0 182478 0 0 0 0 0 0 0 72454 98038 125952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492479 0 0 382026 0 122440 129279 475014 268445 352717 490979 313415 0 285297 479499 339068 283271 0 552278 515639 0 182421 0 141478 593187 110565 530631 0 0 449564 0 0 0 0 462972 430933 540735 0 3876593 0 0 3834134 0 1625177 1845730 3703422 5147638 2390021 1708559 2069623 0 6875567 4669897 1787853 3539860 0 3925596 5108582 0 474063 0 576759 2878593 2396978 3924294 0 0 4859005 0 0 0 0 3880013 2734491 4931441 0 2034367 0 0 0 0 2234599 3121855 2061183 2366788 4047217 207632 3254043 0 141347 4335260 2322509 3543340 0 3330928 1132493 0 595200 0 91863 74030 1397409 159770 0 0 1088947 0 0 0 0 0 100920 435897 0 +AANLVGEEGR MGYG000002528_00945 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,26AUV@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00945 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1763733 0 0 0 0 0 0 0 0 0 2179269 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1722214 0 0 0 0 1809565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433308 0 0 0 0 0 0 0 0 0 288401 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANLVK MGYG000001714_01819 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus_A|s__Coprococcus_A catus|m__MGYG000001714 1.0 COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 UPF0210 protein 1.0 - 1.0 - 1.0 - 1.0 ko:K09157 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 DUF711 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001714_01819 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K09157:K09157; uncharacterized protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9352536 0 +AANNDEKC(Carbamidomethyl)IGVITWMHTFSPAK MGYG000001313_02667;MGYG000001750_01414;MGYG000002478_02453 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2160@1|root,COG2160@2|Bacteria,4NHGG@976|Bacteroidetes,2FMIU@200643|Bacteroidia,4APG1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the conversion of L-arabinose to L-ribulose 1.0 araA 1.0 - 1.0 5.3.1.4 1.0 ko:K01804 1.0 ko00040,ko01100,map00040,map01100 1.0 - 1.0 R01761 1.0 RC00516 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Arabinose_Iso_C,Arabinose_Isome 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_02667 0.3333333333333333 L-arabinose isomerase. L-arabinose ketol-isomerase. Requires a divalent metal ion (the enzyme from the bacterium Escherichia coli prefers Mn(2+)).-!-The enzyme binds beta-L-arabinopyranose and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene-diol mechanism.-!-The enzyme can also convert alpha-D-galactose to D-tagatose with lower efficiency. beta-L-arabinopyranose = L-ribulose. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Metabolic pathways 1.0 K01804:araA; L-arabinose isomerase [EC:5.3.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 760227 0 0 0 0 548551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2711107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1199746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 630319 0 0 0 0 0 0 0 0 0 0 +AANPTAEKPFVLGLPTGSSPLGMYK MGYG000002438_00973 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,22W1C@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00973 1.0 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K02564:nagB, GNPDA; glucosamine-6-phosphate deaminase [EC:3.5.99.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6850205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14766844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANPTPEKPFVLGC(Carbamidomethyl)PTGSSPLGM(Oxidation)YK MGYG000002171_00281;MGYG000002455_02070;MGYG000000196_01768;MGYG000001661_00842;MGYG000003351_04413;MGYG000002549_00225;MGYG000002478_04559;MGYG000002560_02540;MGYG000000243_00067;MGYG000001378_02954;MGYG000004876_00832;MGYG000000013_02920;MGYG000000029_00780 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,4AKMP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_00281 0.07692307692307693 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K02564:nagB, GNPDA; glucosamine-6-phosphate deaminase [EC:3.5.99.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1208100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 712038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANPTPEKPFVLGC(Carbamidomethyl)PTGSSPLGMYK MGYG000002171_00281;MGYG000002455_02070;MGYG000000196_01768;MGYG000001661_00842;MGYG000003351_04413;MGYG000002549_00225;MGYG000002478_04559;MGYG000002560_02540;MGYG000000243_00067;MGYG000001378_02954;MGYG000004876_00832;MGYG000000013_02920;MGYG000000029_00780 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,4AKMP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_00281 0.07692307692307693 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K02564:nagB, GNPDA; glucosamine-6-phosphate deaminase [EC:3.5.99.6] 1.0 none 1.0 774384 1056090 673299 1461003 341220 704956 1498973 1127721 1057186 779783 722701 847521 576042 455299 263080 751127 844741 166074 425181 553764 1123713 660106 385143 1186596 455854 692009 1304836 636922 1092512 989518 1385253 920265 784715 780101 722707 1182654 966180 471258 2538337 1762855 2441834 3616859 2591646 2638802 2735645 3205240 2458185 4268427 4265079 2720776 2238512 3797441 3691686 2584788 2770513 1193334 2823756 2806250 3641870 2812924 1707895 2543196 2957443 3770103 4028772 1139187 2734600 2987459 1927510 2917670 2255843 2763845 3478691 2836819 3037230 2417360 1131506 1043735 1076477 911984 1249035 1608671 1338301 1189398 857890 859021 1135403 1314949 818660 815524 670711 1034830 1207022 2075043 966473 860616 759518 1013614 1653788 1465271 845045 1060113 955892 1595996 1198561 1145319 1316466 1236121 944551 1108543 1182165 1309381 929593 909221 271021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 238489 0 0 0 0 1018114 521042 785241 1277783 1388950 2101397 1448360 1537540 1686565 1023511 1517242 883682 1859664 487693 876892 1534335 1125043 1640073 929365 2089426 1294064 1336956 1629741 2339418 1361024 1441487 1055494 1654112 918658 2177028 1088434 962104 715978 1972019 1793836 1313465 1879117 750095 +AANQAGGITTK MGYG000002298_00339;MGYG000004733_00979;MGYG000000212_03058 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3Y0BX@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit 1.0 rplX 1.0 - 1.0 - 1.0 ko:K02895 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KOW,ribosomal_L24 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002298_00339 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02895:RP-L24, MRPL24, rplX; large subunit ribosomal protein L24 1.0 none 1.0 0 0 0 0 0 2605646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3053091 0 1158511 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299424 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1061832 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2204213 0 819923 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 277197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANQILTDGVADLILLGNPDEIMSLAK MGYG000000243_02864 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0280@1|root,COG0280@2|Bacteria,4NGX5@976|Bacteroidetes,2FMKY@200643|Bacteroidia,4AK60@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 pta 1.0 - 1.0 2.3.1.8 1.0 ko:K00625,ko:K13788 1.0 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 1.0 M00357,M00579 1.0 R00230,R00921 1.0 RC00004,RC02746,RC02816 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AAA_26,DRTGG,PTA_PTB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02864 1.0 phosphate acetyltransferase. phosphotransacetylase. Also acts with other short-chain acyl-CoAs. acetyl-CoA + phosphate = acetyl phosphate + CoA. 1.0 1.0 1.0 1.0 Taurine and hypotaurine metabolism|Pyruvate metabolism|Propanoate metabolism|Methane metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00625:pta; phosphate acetyltransferase [EC:2.3.1.8]|K13788:pta; phosphate acetyltransferase [EC:2.3.1.8] 1.0 none 1.0 0 0 0 0 2304167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2292764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3600654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANQQGGIITK MGYG000001338_02796;MGYG000000200_01102 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3Y0BX@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit 1.0 rplX 1.0 - 1.0 - 1.0 ko:K02895 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 KOW,ribosomal_L24 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_02796 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02895:RP-L24, MRPL24, rplX; large subunit ribosomal protein L24 1.0 none 1.0 0 3012966 1992021 0 4793586 0 0 0 0 0 2748463 0 2374350 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1211158 3571928 1080709 0 0 0 0 1796065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 382589 0 0 0 0 0 0 0 2064453 363503 0 0 0 0 0 0 0 0 0 576276 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 618982 1668339 314504 0 0 0 0 0 0 6395297 1891304 0 4091769 0 0 0 0 0 1985679 0 1983337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6178742 4923176 2359857 0 0 0 0 2064911 0 619856 0 0 0 0 0 0 0 0 615255 0 839556 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANQQGGIVSQEAPIDASN(Deamidated)VNLVC(Carbamidomethyl)PEC(Carbamidomethyl)GK MGYG000003122_00592;MGYG000003266_00871;MGYG000001636_00357;MGYG000002050_01545 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CVUJ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome 1.0 rplN 1.0 - 1.0 - 1.0 ko:K02874 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L14 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003122_00592 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02874:RP-L14, MRPL14, rplN; large subunit ribosomal protein L14 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 647119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANQQGGIVSQEAPIDASNVNLVC(Carbamidomethyl)PEC(Carbamidomethyl)GK MGYG000003122_00592;MGYG000003266_00871;MGYG000001636_00357;MGYG000002050_01545 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CVUJ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome 1.0 rplN 1.0 - 1.0 - 1.0 ko:K02874 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L14 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003122_00592 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02874:RP-L14, MRPL14, rplN; large subunit ribosomal protein L14 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1043421 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANSEYQTR MGYG000003693_01542 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0251@1|root,COG0251@2|Bacteria,4NEVA@976|Bacteroidetes,2FN38@200643|Bacteroidia,4AKJZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 endoribonuclease L-PSP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DAHP_synth_1,Ribonuc_L-PSP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_01542 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 303166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165552 0 0 0 0 615044 0 0 0 0 680694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 180662 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 442122 0 0 0 0 215306 0 0 0 0 133668 0 0 0 0 0 0 0 0 0 0 +AANSFGSVK MGYG000002218_00670;MGYG000000138_03130;MGYG000000044_02742 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides 1.0 COG3063@1|root,COG3063@2|Bacteria,4PKG6@976|Bacteroidetes,2G3G2@200643|Bacteroidia,2322F@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 NU 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002218_00670 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 1406553 1360405 0 0 1399867 2483983 1998431 0 1734055 0 2153224 0 1646439 1404939 0 0 2437916 0 0 2209113 1715115 2566947 0 1600830 2044931 0 2288668 0 1991943 1935442 2819911 1616312 0 1852423 0 1933799 1353133 266231 588447 972798 0 0 1067419 692192 255981 0 362393 0 265557 0 514867 231744 0 0 279913 0 0 396244 828424 0 694561 195705 689341 0 404747 0 766305 498774 307235 414319 0 340572 0 432038 0 1095588 1195452 1296078 0 0 1516647 1707222 1577998 0 1564782 0 1055043 0 1351825 1172269 0 0 1560972 0 0 1670272 1409489 1251525 1635281 805937 874756 0 1189727 0 1353807 1858011 1597233 1110721 0 1516626 0 1412223 1340040 1593783 1705059 1682104 0 0 1512058 2287403 2228972 0 2163507 0 1998008 0 1777046 1862497 0 0 1621073 0 0 1755692 1322193 1072758 1422812 1557911 1648543 0 1781089 0 1854916 2128731 2257305 1443846 0 1606400 0 1906902 822974 782305 808911 720465 0 0 771365 1453684 0 0 536339 0 0 0 922620 185498 0 0 2597110 0 0 0 750442 2126046 553544 788615 0 0 1710547 0 0 108428 1112845 472408 0 688234 0 169640 643086 +AANSYVK MGYG000002438_00958 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG0446@1|root,COG0446@2|Bacteria,4NE3A@976|Bacteroidetes,2FRH5@200643|Bacteroidia,22WU3@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_00958 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6153680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2073279 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANTDLAGALQGK MGYG000002549_04077;MGYG000000196_02346 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1629@1|root,COG4206@1|root,COG4206@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AWFC@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002549_04077 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2727287 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1229781 0 0 0 0 140449 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2973108 0 0 0 0 297409 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANTISPVA(Ala->Thr)ALQGK MGYG000002614_01265;MGYG000002478_00657;MGYG000002560_00458;MGYG000000236_01278;MGYG000001337_02403 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKGC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02014 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002614_01265 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02014:TC.FEV.OM; iron complex outermembrane recepter protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1735348 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1799416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANTISPVAALQGK MGYG000002614_01265;MGYG000002478_00657;MGYG000002560_00458;MGYG000000236_01278;MGYG000001337_02403 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKGC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02014 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002614_01265 0.2 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02014:TC.FEV.OM; iron complex outermembrane recepter protein 1.0 none 1.0 0 0 2674823 3532488 4123556 3267952 4666915 2121237 2964416 2669740 2621173 2729479 4989970 2951312 2189002 4927344 3719720 1427962 2690343 3012357 3210458 2659290 2263957 3938330 2473972 2998178 3495996 2118816 3312395 2894166 3721520 3480634 3092425 1148811 3195835 3801723 3104327 2735847 2421117 2040041 2373379 2908093 3697324 2317445 2040690 2501649 2945910 2289833 2873741 2403669 4440222 2885544 2618028 4864320 1896632 1326879 2492090 2684667 2458190 2511889 1901257 1781494 2507201 2440840 2538791 1560718 2579699 2491298 1862048 2854365 2546533 2195846 2644347 2364832 2566712 2353314 0 0 0 195070 0 281412 0 0 0 0 240352 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 624668 0 0 345713 0 0 230449 428555 286111 228282 277063 279204 369849 403501 530313 0 0 0 500673 479463 354423 0 0 0 475600 575072 390902 0 0 192798 0 186476 0 0 565441 670811 646647 0 1214141 830005 1093121 1340411 1598166 1243185 1959787 2428746 2690332 1083051 825749 480905 2176960 1086066 1585705 1601726 2181912 4566027 1470445 2799175 1093060 861763 3935111 1129548 2055215 1965040 1687364 3541269 1936227 1920897 1273541 960061 499759 3020588 2596417 1758063 2113701 1048764 +AANTISPVTALQGK MGYG000002478_00647 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDU8@976|Bacteroidetes,2FMRZ@200643|Bacteroidia,4AKGC@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02014 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.B.14 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00647 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02014:TC.FEV.OM; iron complex outermembrane recepter protein 1.0 none 1.0 391284 263924 245442 411072 363169 378420 388368 0 380867 288367 321359 351988 616906 256278 0 552870 430723 377569 421003 0 327000 365107 240458 476079 0 319491 345925 138323 318072 404132 377256 320357 321090 0 416320 280188 405766 258306 1567500 1341009 1547701 1603385 1654335 1326530 1134859 1276861 1436455 1325129 1401575 1268548 1470673 1507780 0 1691687 1338691 787215 1637515 0 1348096 1722988 1171774 1300262 0 1366962 1378903 1046633 1564180 1323112 1166160 1345674 1516108 0 1315919 1509661 1511347 1286292 1715262 1406751 0 1395519 2948338 2042796 1955003 1297502 2101289 1568473 1509407 1961966 0 1653601 0 2075443 1096349 2831723 1841770 0 1294213 1507523 0 1844460 0 1539425 1737722 2013635 0 0 2178463 1624982 1388595 0 1837562 1901020 2111309 0 0 0 841436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 894085 0 0 224473 0 678201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 415026 0 0 0 0 0 0 0 0 0 0 645704 0 +AANTNLLK MGYG000002171_00304 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp002493165|m__MGYG000002171 1.0 COG0702@1|root,COG0702@2|Bacteria,4NEPE@976|Bacteroidetes,2FMBU@200643|Bacteroidia,4ANN0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_00304 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 3230790 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1679444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1268850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVA(Ala->Val)LVGTEK MGYG000000142_01601;MGYG000000301_01353;MGYG000000212_01002;MGYG000002312_02491;MGYG000003012_02044;MGYG000003822_02069;MGYG000000002_00289;MGYG000003821_00240;MGYG000000171_01279;MGYG000002772_00614;MGYG000000200_00386;MGYG000000263_00751;MGYG000001338_00128;MGYG000004785_00404;MGYG000000031_02918;MGYG000002186_00350;MGYG000000252_02288;MGYG000004733_01675;MGYG000002298_00401;MGYG000000216_00449 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.95 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.95 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01601 0.05 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4178720 0 0 0 0 0 0 0 0 0 0 2833144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVAEDELADDGASNPHVK MGYG000000133_01138 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3XZ6D@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner 1.0 ychF 1.0 - 1.0 - 1.0 ko:K06942 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009 1.0 - 1.0 - 1.0 - 1.0 MMR_HSR1,YchF-GTPase_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01138 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K06942:ychF; ribosome-binding ATPase 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532426 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVALIGYEK MGYG000000198_03138;MGYG000001564_03639 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,2235C@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 CQ 1.0 BMC domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_03138 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1243499 0 1173047 2965965 1296932 1214243 696212 1395522 2367892 3184767 1599207 0 0 2892915 3179139 0 1119676 0 0 2107061 2322846 1009173 0 704608 1263992 1890341 2070602 0 1797746 2094818 0 0 859203 2226600 0 1828877 1915341 896033 1529691 0 0 2336510 257421 353561 718613 1558923 1925954 2100786 325729 0 0 1934642 1912236 0 647432 0 0 1303600 1031864 307209 0 0 1672328 2254227 2038146 0 1677911 0 0 0 0 1418083 0 1984299 1842108 719141 5923592 0 3635909 3408708 1740599 527168 2464375 4258965 5234416 3797081 2608534 0 0 5575349 5417678 0 1001505 0 0 4624271 4379431 2656637 0 2314743 1492108 4634346 5270137 0 6541265 4113656 0 0 2483199 1899074 0 5236836 3785169 2697979 5027117 0 6431442 4297139 3208381 4726749 4368262 5566955 4570667 6223365 3505898 0 0 5114393 4594649 0 4150161 0 0 3866306 4118177 4106212 0 3759903 0 4396899 4713519 0 4687259 3641828 0 0 4873019 7046290 0 5160953 4244915 4056995 503287 0 842783 326640 360799 387614 640633 274613 519077 387335 772952 0 0 416006 589064 0 350397 0 0 339240 293471 325708 0 666864 332739 391137 617582 0 534088 519569 0 0 1165589 630354 0 246820 545460 1015319 +AANVALVGTEK MGYG000000142_01601;MGYG000000301_01353;MGYG000000212_01002;MGYG000002312_02491;MGYG000003012_02044;MGYG000003822_02069;MGYG000000002_00289;MGYG000003821_00240;MGYG000000171_01279;MGYG000002772_00614;MGYG000000200_00386;MGYG000000263_00751;MGYG000001338_00128;MGYG000004785_00404;MGYG000000031_02918;MGYG000002186_00350;MGYG000000252_02288;MGYG000004733_01675;MGYG000002298_00401;MGYG000000216_00449 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.95 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.95 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01601 0.05 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 16963546 17549188 18169804 12004261 19976812 24065438 10223383 19393281 12552768 17647225 20907049 16900422 19849105 14358538 19544718 18644135 24394079 22004522 15135266 19455304 25864384 25219942 14685160 13456926 18910085 14269715 13071632 18453848 21867661 19172702 12317999 17169799 14651336 15713174 17303690 10742991 14649119 16900674 21613531 19826110 15015307 14664261 17965957 9169119 15921706 17134996 17708850 10377299 14051654 7578707 9615285 13514238 13382835 7839375 28419646 25223950 11685288 16661186 14466651 8084677 16517031 14938651 12790325 15732358 16950397 19864305 26380059 14911773 20057811 13849808 15530355 19994303 25261102 18804113 18897881 18216029 27093322 29473365 25422290 19280429 18615452 23539563 21874169 27203932 20685894 29442479 19724059 17074345 20501322 22226561 31758254 22230839 32909608 14086438 29024261 23291687 23523285 31874097 20666607 22272233 27304418 25194283 28268944 21851708 23664376 28755806 27630090 26773839 24649386 30655329 25919144 19504480 22990346 22771238 11069524 16954643 12372566 0 14015075 11658390 11212384 11172756 10284349 14964628 10977513 11744445 10827952 12701076 10028551 11252298 23057743 11310238 8479453 11983490 10675881 14557744 0 14553573 9226578 8813752 0 16679566 40169149 13107228 16091670 12150216 13753145 7662992 9617107 10146520 0 14984379 32828023 31592531 36643196 42494714 13258505 37223924 47582306 31633036 26785391 42682515 41801792 32609424 28485979 38435634 30038435 20489136 36176104 8323545 31297938 15793326 41072007 30059166 11843586 28095787 26830054 42546408 32911557 12094919 42666529 17807196 30560586 33686270 49015607 33487415 20727836 45189347 19919529 28342586 +AANVALVGTEK(Delta_H(4)C(6)) MGYG000000142_01601;MGYG000000301_01353;MGYG000000212_01002;MGYG000002312_02491;MGYG000003012_02044;MGYG000003822_02069;MGYG000000002_00289;MGYG000003821_00240;MGYG000000171_01279;MGYG000002772_00614;MGYG000000200_00386;MGYG000000263_00751;MGYG000001338_00128;MGYG000004785_00404;MGYG000000031_02918;MGYG000002186_00350;MGYG000000252_02288;MGYG000004733_01675;MGYG000002298_00401;MGYG000000216_00449 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.95 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.95 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_01601 0.05 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4040894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVIR MGYG000003362_00528 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Dysgonomonadaceae|g__Dysgonomonas|s__Dysgonomonas sp900079735|m__MGYG000003362 1.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,4NETY@976|Bacteroidetes,2FM2Z@200643|Bacteroidia,22W21@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate 1.0 purL 1.0 - 1.0 6.3.5.3 1.0 ko:K01952 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04463 1.0 RC00010,RC01160 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C,GATase_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003362_00528 1.0 phosphoribosylformylglycinamidine synthase. phosphoribosylformylglycinamidine synthetase. - ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D- ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D- ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01952:PFAS, purL; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVMEIYGSK MGYG000002272_00822;MGYG000001300_00352;MGYG000002040_00733;MGYG000000022_01091;MGYG000003166_01369;MGYG000002545_02252;MGYG000002641_00365;MGYG000003899_00843 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 S 1.0 glutamine synthetase 1.0 glnA 0.875 - 1.0 6.3.1.2 1.0 ko:K01915 1.0 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 1.0 - 1.0 R00253 1.0 RC00010,RC02798 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 GSIII_N,Gln-synt_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002272_00822 0.125 glutamine synthetase. L-glutamine synthetase. Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life.-!-Several types have been described, differing in their oligomeric structures and cofactor requirements. ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Glyoxylate and dicarboxylate metabolism|Nitrogen metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Biosynthesis of amino acids|Two-component system|Necroptosis|Glutamatergic synapse|GABAergic synapse 1.0 K01915:glnA, GLUL; glutamine synthetase [EC:6.3.1.2] 1.0 none 1.0 0 0 1576777 0 506385 1507356 1426750 0 1265543 0 1490472 1106622 1122546 1348180 0 0 1001397 1298988 1752414 1516209 1077985 1892680 1550782 991560 1596511 1655566 0 1565975 0 1107071 0 1192218 1513446 1543775 0 1298936 1416631 6088365 2141052 1715961 1875583 0 1456447 1518102 2887994 0 2061785 0 0 2133195 902946 2678598 0 0 2343003 0 2546018 2845227 1355816 0 0 1751526 2437086 0 0 0 0 0 0 1774644 1877664 1954456 0 2001171 1971621 2121586 412231 837897 632722 0 1101654 956700 777769 0 848343 0 627213 0 906939 694795 0 0 639626 1735436 474435 478133 937695 713514 1883846 1085432 578264 982911 0 2098740 0 953728 0 755142 511295 234831 0 797120 286582 731694 1088069 1016360 1067126 0 1012953 962910 1286746 0 783933 0 612079 1260040 1473320 573595 0 0 1117032 0 1096356 1418244 1153191 1761580 0 0 1026157 872026 0 0 0 1159476 0 1162377 1335509 1094856 0 882377 974624 1057509 433493 479562 539845 0 674811 557887 514940 0 504629 0 309926 491563 0 249533 0 0 269399 0 0 233873 451146 511262 1888790 712318 418885 302662 0 2025600 0 567947 0 576140 503807 406459 0 331097 369017 651934 +AANVN(Asn->Ala)LIGYEK MGYG000004667_05617 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium|s__Clostridium beijerinckii|m__MGYG000004667 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004667_05617 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 959679 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1934883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5119804 0 0 0 0 0 4984440 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVN(Deamidated)LVGYEK MGYG000002854_00976 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Peptostreptococcales|f__Peptostreptococcaceae|g__Peptacetobacter|s__Peptacetobacter sp900539645|m__MGYG000002854 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,22HEI@1570339|Peptoniphilaceae 1.0 186801|Clostridia 1.0 CQ 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002854_00976 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVPAFVSGK MGYG000002494_02496;MGYG000002506_03710;MGYG000002534_04602;MGYG000002323_03976 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0776@1|root,COG0776@2|Bacteria,1MZ5B@1224|Proteobacteria,1S8VH@1236|Gammaproteobacteria,3XPW4@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 L 1.0 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions 1.0 hupA 1.0 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006323,GO:0006351,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:1990104,GO:1990178,GO:2001141 1.0 - 1.0 ko:K03530,ko:K05787 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03032,ko03036,ko03400 1.0 - 1.0 - 1.0 - 1.0 Bac_DNA_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02496 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03530:hupB; DNA-binding protein HU-beta|K05787:hupA; DNA-binding protein HU-alpha 1.0 none 1.0 0 0 1471151 0 0 2189095 0 0 1575715 1946436 0 0 0 1756945 0 0 2108338 0 0 1718589 0 2042616 0 2204837 1702344 0 0 0 0 0 0 0 1519973 1856926 1983818 1718692 0 1377905 0 0 1407480 0 0 1382982 0 0 1803189 747540 0 0 0 1151450 0 0 1194358 0 3374026 1531984 0 1185029 0 1022266 1431106 0 0 0 0 0 0 0 1339395 1167880 933477 1156126 0 1256443 0 0 1274882 0 0 1708204 0 0 1636342 1027301 0 0 0 1344081 0 0 793313 0 1045370 932652 0 1496763 0 2250593 1007945 0 0 0 0 0 0 0 797785 1180346 1217497 1406473 0 1189966 0 0 2547262 0 0 2548297 0 0 1755612 1986550 0 0 0 1899000 0 0 1453449 0 1891804 1851558 0 2053848 0 1528176 2482269 0 0 0 0 0 0 0 2224782 3218206 1999135 2794691 0 1848201 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 335276 0 0 0 0 0 0 440661 0 0 0 0 0 0 0 0 0 379249 0 0 0 280659 +AANVS(Deoxy[S](Ser->Ala)LVGTEK MGYG000000184_02439 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A luti|m__MGYG000000184 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 1.0 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_02439 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10382705 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVSLVGYEK MGYG000004087_00692;MGYG000001564_03645;MGYG000000205_00403;MGYG000000198_03144 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 0.75 186801|Clostridia 0.75 CQ 1.0 PFAM microcompartments protein 0.75 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004087_00692 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 1276512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1265940 0 1454122 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 378283 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 539579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2361860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2711885 0 2811170 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5143739 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4855153 0 3609205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 300145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 302551 0 469838 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVTLIGK MGYG000000092_00836;MGYG000001311_03739;MGYG000000092_00835;MGYG000001171_01490;MGYG000000198_01506;MGYG000000099_01306;MGYG000000099_01305;MGYG000001367_03226;MGYG000000150_00833;MGYG000001698_02372;MGYG000000150_00816;MGYG000001698_02371;MGYG000003185_00408;MGYG000004630_01930;MGYG000000413_00044;MGYG000004630_01931;MGYG000000359_01134;MGYG000000359_01133;MGYG000001617_00515;MGYG000000179_01371;MGYG000000233_02830;MGYG000000359_00758;MGYG000003589_02226 domain d__Bacteria 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia 0.30434782608695654 186801|Clostridia 1.0 CQ 1.0 Carbon dioxide concentrating mechanism carboxysome shell protein 0.30434782608695654 - 0.6956521739130435 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000092_00836 0.043478260869565216 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 16932820 14478121 7769544 15000920 0 14834381 14023032 0 15019965 16983116 0 0 0 17766748 0 0 0 0 0 0 0 8675562 0 0 0 18494753 19085038 0 0 0 10386501 15134925 0 4421103 0 15791934 0 0 14166102 7019910 13315162 13214181 0 9550854 7826489 12503659 0 0 0 12079872 0 13331346 16551181 0 0 0 13637916 15958765 0 9320509 0 8316013 11908936 13444906 11520723 0 0 14172239 7157545 10315423 11757686 10346214 12431562 0 0 13944165 0 9527558 0 12932728 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7396979 0 0 0 0 0 0 0 0 10973069 0 0 0 0 0 0 0 0 0 0 0 0 7402470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVTLIGK(Lys->Arg) MGYG000000092_00836;MGYG000001311_03739;MGYG000000092_00835;MGYG000001171_01490;MGYG000000198_01506;MGYG000000099_01306;MGYG000000099_01305;MGYG000001367_03226;MGYG000000150_00833;MGYG000001698_02372;MGYG000000150_00816;MGYG000001698_02371;MGYG000003185_00408;MGYG000004630_01930;MGYG000000413_00044;MGYG000004630_01931;MGYG000000359_01134;MGYG000000359_01133;MGYG000001617_00515;MGYG000000179_01371;MGYG000000233_02830;MGYG000000359_00758;MGYG000003589_02226 domain d__Bacteria 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia 0.30434782608695654 186801|Clostridia 1.0 CQ 1.0 Carbon dioxide concentrating mechanism carboxysome shell protein 0.30434782608695654 - 0.6956521739130435 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000092_00836 0.043478260869565216 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 0 0 0 816217 0 0 0 0 798092 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 638613 0 0 0 0 520522 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 460427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVTLLGK MGYG000000198_01506;MGYG000001367_03225;MGYG000001367_03226;MGYG000000150_00833;MGYG000002829_04822;MGYG000000150_00816;MGYG000003185_00408;MGYG000000359_01134;MGYG000000413_00044;MGYG000000359_01133;MGYG000002829_01657;MGYG000001617_00515;MGYG000000179_01371;MGYG000000233_02830;MGYG000000359_00758;MGYG000003589_02226 domain d__Bacteria 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 0.3125 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 0.5 - 0.5625 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_01506 0.0625 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 15301137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8128000 0 0 16992188 0 0 0 10339795 0 0 0 0 0 0 0 0 0 0 10147913 0 0 0 0 0 0 0 0 0 15177528 0 0 13161053 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7703442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1720418 0 0 0 0 15459581 0 0 0 0 0 0 0 0 1302759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVTLVGK MGYG000000152_02876 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lacrimispora|s__Lacrimispora sp902363835|m__MGYG000000152 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 1.0 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000152_02876 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 0 0 0 584253 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1315488 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVV(Val->Ala)LVGTEK MGYG000000175_02141;MGYG000000127_01924;MGYG000004799_00495;MGYG000003427_01862;MGYG000002596_02058;MGYG000000268_01896 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.5 - 1.0 - 1.0 - 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000175_02141 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 0.8333333333333334 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6117305 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANVVLVGTEK MGYG000000175_02141;MGYG000000127_01924;MGYG000004799_00495;MGYG000003427_01862;MGYG000002596_02058;MGYG000000268_01896 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 CQ 1.0 COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein 0.5 - 1.0 - 1.0 - 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000175_02141 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 0.8333333333333334 none 1.0 0 0 0 0 0 0 0 0 0 793806 0 0 0 745038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 359396 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 936379 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94243 0 0 0 721411 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 768881 0 0 0 5821062 0 0 0 0 0 0 0 0 2684436 0 0 0 0 0 0 0 0 458734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 225189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 195159 0 0 0 0 0 0 0 0 0 0 +AANVYLIGK MGYG000003142_02726;MGYG000003142_02725 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Clostridiales|f__Clostridiaceae|g__Clostridium_J|s__Clostridium_J sp900547625|m__MGYG000003142 1.0 COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,36JRW@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 CQ 1.0 PFAM microcompartments protein 1.0 NPD7_940 1.0 - 1.0 - 1.0 ko:K04027 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 BMC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003142_02726 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04027:eutM; ethanolamine utilization protein EutM 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4525462 0 0 0 0 0 0 0 0 0 0 4130646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746129 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANWLLR MGYG000003693_00985;MGYG000000243_02341;MGYG000000196_00133 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG3637@1|root,COG3637@2|Bacteria,4NEA6@976|Bacteroidetes,2FNRM@200643|Bacteroidia,4AKT2@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 SusD family 1.0 susD 1.0 GO:0001871,GO:0003674,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0006073,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0019867,GO:0030246,GO:0030247,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0046872,GO:0071704,GO:2001070 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_00985 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 1311155 0 0 0 0 0 0 0 0 0 0 0 923258 881036 0 0 0 0 1335960 0 0 0 0 1059273 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1116073 0 0 0 0 2071192 0 0 0 0 1533754 0 0 0 0 0 0 0 0 0 0 0 0 0 0 763467 0 0 0 0 0 0 0 0 0 0 0 298571 1513409 0 0 0 0 1410350 0 0 0 0 1170709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159433 0 0 0 0 2452268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AANYALK MGYG000002438_01848 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG5107@1|root,COG5107@2|Bacteria,4NEPG@976|Bacteroidetes,2FNHC@200643|Bacteroidia,22WFC@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 A 1.0 Domain of Unknown Function (DUF349) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF349 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01848 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 177127 0 0 0 0 0 0 0 0 309008 0 0 0 0 0 0 0 0 260137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 280632 0 0 0 0 0 0 0 0 375214 0 0 0 0 0 0 0 0 350615 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 465386 0 0 0 0 0 0 0 0 1066920 0 0 0 0 0 0 0 0 702578 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 593080 0 0 0 0 0 0 0 0 1287617 0 0 0 0 0 0 0 0 847410 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1733105 0 0 0 0 0 0 0 0 1917833 0 0 0 0 0 0 0 0 1938608 0 0 0 0 0 0 0 0 +AANYLSIGQIYLR MGYG000000756_01025;MGYG000003683_00701 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CZT5@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 G 1.0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 1.0 xfp 1.0 - 1.0 4.1.2.22,4.1.2.9 1.0 ko:K01621 1.0 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 1.0 - 1.0 R00761,R01621 1.0 RC00032,RC00226 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 XFP,XFP_C,XFP_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000756_01025 0.5 fructose-6-phosphate phosphoketolase. | phosphoketolase. acetylating). | xylulose-5-phosphate phosphoketolase. Also acts on D-xylulose 5-phosphate. keto-D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O. | D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Metabolic pathways|Microbial metabolism in diverse environments 1.0 K01621:xfp, xpk; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22] 1.0 none 1.0 437944 0 405778 382807 0 29535 130717 40809 0 0 180279 0 690041 0 0 382785 0 56740 0 757922 0 0 49544 0 0 33758 0 32988 106174 0 205234 0 217713 0 0 0 0 455048 930564 0 2008448 1165044 1139229 2261416 1174281 1002502 0 1034899 1581189 0 3994070 419587 0 1141164 0 6976505 0 710144 0 1032567 1739609 3718814 0 603141 1351138 3618247 1540498 0 4144431 0 1622918 0 0 914202 889239 6883825 1359068 0 241405 252979 0 430029 0 1392705 0 774843 0 0 581964 0 0 1490419 0 0 0 1413367 0 1821905 0 110019 0 0 1006015 0 435312 0 0 0 4314719 0 0 0 0 0 0 0 0 0 1200037 0 159979 120773 0 0 0 0 0 0 0 0 0 0 0 349078 0 0 0 478639 0 481264 510006 309135 420138 0 0 0 203735 0 0 498437 234202 1735330 244982 0 82116 256545 666769 462694 90230 0 0 2528031 7790634 0 455044 0 0 243277 0 148242 0 364771 0 0 119614 421340 0 268768 235244 0 0 0 4674915 0 0 0 0 0 0 313630 +AANYVASK MGYG000000243_00067;MGYG000002478_04559 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0363@1|root,COG0363@2|Bacteria,4NHF8@976|Bacteroidetes,2FN1D@200643|Bacteroidia,4AKMP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion 1.0 nagB 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.0 3.5.99.6 1.0 ko:K02564 1.0 ko00520,ko01100,map00520,map01100 1.0 - 1.0 R00765 1.0 RC00163 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Glucosamine_iso 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00067 0.5 glucosamine-6-phosphate deaminase. phosphoglucosaminisomerase. Isomerization of the aldose-ketose type converts the -CH(-NH2)-CH=O group of glucosamine 6-phosphate into -C(=NH)-CH2-OH, forming 2-deoxy-2-imino-D-arabino-hexitol which then hydrolyzes to yield fructose 6-phosphate and ammonia.-!-N-acetyl-D-glucosamine 6-phosphate, which is not broken down, activates the enzyme.-!-Formerly EC 5.3.1.10. alpha-D-glucosamine 6-phosphate + H2O = beta-D-fructose 6-phosphate + NH4(+). 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K02564:nagB, GNPDA; glucosamine-6-phosphate deaminase [EC:3.5.99.6] 1.0 none 1.0 0 0 1208219 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 829782 0 0 0 0 0 0 0 1610554 0 0 0 0 1262921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158000 0 0 0 0 0 0 0 71364 0 0 0 0 246893 0 0 264242 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 227476 0 0 0 0 0 0 0 240274 0 0 0 0 0 0 0 123980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 226506 0 0 0 0 0 +AANYWR MGYG000000243_03182 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0457@1|root,COG0457@2|Bacteria,4NG3F@976|Bacteroidetes,2FM0I@200643|Bacteroidia,4AKP7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03182 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 3056726 0 0 0 0 1014826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1731775 0 2882940 0 0 0 0 2549516 0 0 584709 0 0 0 0 774691 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 485588 0 505350 0 0 0 0 539257 0 0 164618 0 0 0 0 226181 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 299567 0 303674 0 0 0 0 275864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 240439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215312 0 0 0 0 0 0 0 +AAPAAAPAAAAA(Ala->Pro)K MGYG000002506_04250 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,3XP9X@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) 1.0 aceE 1.0 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.0 1.2.4.1 1.0 ko:K00163 1.0 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 1.0 M00307 1.0 R00014,R00209,R01699,R03270 1.0 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 e_coli_core.b0114,iAF1260.b0114,iBWG_1329.BWG_0107,iE2348C_1286.E2348C_0117,iEC55989_1330.EC55989_0107,iECDH10B_1368.ECDH10B_0094,iECDH1ME8569_1439.ECDH1ME8569_0108,iECH74115_1262.ECH74115_0121,iECIAI1_1343.ECIAI1_0112,iECNA114_1301.ECNA114_0106,iECO103_1326.ECO103_0114,iECO111_1330.ECO111_0115,iECO26_1355.ECO26_0116,iECSE_1348.ECSE_0114,iECSF_1327.ECSF_0127,iECSP_1301.ECSP_0115,iECUMN_1333.ECUMN_0111,iECW_1372.ECW_m0111,iECs_1301.ECs0118,iEKO11_1354.EKO11_3802,iETEC_1333.ETEC_0110,iEcDH1_1363.EcDH1_3488,iEcE24377_1341.EcE24377A_0116,iEcHS_1320.EcHS_A0118,iEcSMS35_1347.EcSMS35_0124,iEcolC_1368.EcolC_3545,iG2583_1286.G2583_0118,iJO1366.b0114,iJR904.b0114,iUMNK88_1353.UMNK88_112,iWFL_1372.ECW_m0111,iY75_1357.Y75_RS00580,iZ_1308.Z0124 1.0 Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04250 1.0 pyruvate dehydrogenase (acetyl-transferring). pyruvic dehydrogenase. It is a component (in multiple copies) of EC 1.2.1.104 in which it is bound to a core of molecules of EC 2.3.1.12, which also binds multiple copies of EC 1.8.1.4.-!-It does not act on free lipoamide or lipoyllysine, but only on the lipoyllysine residue in EC 2.3.1.12. H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + pyruvate = CO2 + N(6)-[(R)-S(8)- acetyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00163:aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1721993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAAPAAAPK MGYG000004769_01105;MGYG000004276_00434 domain d__Bacteria 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 0.5 909932|Negativicutes 0.5 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 0.5 gcdC 1.0 - 1.0 4.1.1.70 0.5 ko:K01615 0.5 ko00362,ko00650,ko01120,map00362,map00650,map01120 0.5 - 1.0 R03028 0.5 RC00832 0.5 ko00000,ko00001,ko01000,ko02000 0.5 3.B.1.1.3 0.5 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01105 0.5 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 0.5 0.5 0.5 0.5 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 0.5 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2062630 846454 0 0 603210 0 0 493469 934411 0 0 773365 0 377342 0 0 0 0 0 0 0 0 431066 0 860390 0 0 0 0 0 0 911510 0 0 0 0 911172 815051 482587 481621 0 0 1201166 0 0 508682 930429 0 0 1021186 0 905620 0 0 2253064 0 0 0 854358 1925405 986072 0 892591 0 2185434 0 0 0 0 742268 0 0 906467 0 618245 699734 0 0 0 0 0 0 0 948246 120415 0 0 326759 0 1169197 0 0 612533 0 0 0 0 0 0 0 389840 0 0 0 0 0 0 757486 0 1284158 1094510 1311147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAAPAAPK MGYG000002279_00505;MGYG000002992_01786;MGYG000000038_00467 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,27VPV@189330|Dorea 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_00505 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 2246496 0 971570 0 0 0 1435089 0 0 1785772 0 0 2550551 0 0 0 3019834 0 0 0 0 0 0 1657806 1600776 0 0 0 0 0 1580731 0 0 1327780 1602327 643932 0 0 0 0 2025572 0 0 0 0 0 0 2059126 0 0 2132033 0 0 0 3309760 2076429 0 0 0 0 0 2333011 2130784 0 0 0 0 0 0 0 0 0 0 0 0 0 1312875 0 0 0 0 0 0 0 0 0 0 0 3216108 0 0 0 0 5684670 0 0 0 0 0 0 3407325 0 0 0 0 0 2644739 0 0 1615987 1249559 0 0 0 1683651 0 1582385 0 0 0 0 0 0 1647162 0 0 2218492 0 0 0 1270934 0 0 0 0 0 0 0 0 0 0 0 0 0 1978253 0 0 2483058 1936917 1365723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAAPAAPR(Arg->Lys) MGYG000003937_01659 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger qucibialis|m__MGYG000003937 1.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 D 1.0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity 1.0 ftsZ 1.0 - 1.0 - 1.0 ko:K03531 1.0 ko04112,map04112 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02048,ko03036,ko04812 1.0 - 1.0 - 1.0 - 1.0 FtsZ_C,Tubulin 1.0 - 1.0 - 1.0 CBM50 1.0 - 1.0 MGYG000003937_01659 1.0 - - - - 1.0 1.0 1.0 1.0 Cell cycle - Caulobacter 1.0 K03531:ftsZ; cell division protein FtsZ 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 1720506 0 0 0 0 0 4262818 0 0 0 0 2916389 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAAPAPAAK MGYG000004769_01105 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01105 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 623103 0 0 0 0 0 0 0 0 0 0 0 548440 0 0 0 0 0 0 0 0 0 0 0 0 632406 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 728811 0 0 0 0 0 0 0 1008568 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAAPAPAAKPVAAGAATISAPMPGK MGYG000004769_01105 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01105 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 463696 0 506054 0 0 0 0 0 0 0 0 0 0 453387 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAAPK MGYG000000743_02099;MGYG000000031_02585;MGYG000003486_02407;MGYG000004769_01105;MGYG000000135_00626;MGYG000000467_01964;MGYG000003012_01442;MGYG000000170_01348;MGYG000000249_01881;MGYG000004271_01071;MGYG000000325_01536;MGYG000000205_01179;MGYG000002544_00055;MGYG000004482_00849;MGYG000000806_02004;MGYG000004869_00217;MGYG000000212_00763;MGYG000000201_01806;MGYG000000142_00945;MGYG000000171_00279;MGYG000000150_03570;MGYG000002802_01947;MGYG000000213_01127;MGYG000002298_00907;MGYG000002312_01224;MGYG000000002_01398;MGYG000000022_01358;MGYG000004839_00782;MGYG000004884_00770;MGYG000000216_00194;MGYG000000271_00470;MGYG000004719_00224;MGYG000003891_01453;MGYG000001338_01632;MGYG000000255_00810;MGYG000001689_02350;MGYG000004501_00375;MGYG000000182_00099;MGYG000003215_02241;MGYG000002651_00052;MGYG000000118_00820;MGYG000003684_05217;MGYG000000200_00817;MGYG000000233_00100;MGYG000004701_00748;MGYG000000633_01449;MGYG000002794_00735;MGYG000004276_00434 domain d__Bacteria 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 0.3541666666666667 186801|Clostridia 0.8333333333333334 I 0.8125 Biotin-requiring enzyme 0.6666666666666666 gcdC 0.8125 - 0.9791666666666666 - 0.9375 - 0.8541666666666666 - 0.8958333333333334 - 0.9375 - 0.9583333333333334 - 0.9583333333333334 - 0.8541666666666666 - 0.9583333333333334 - 1.0 - 1.0 Biotin_lipoyl 0.8125 - 1.0 - 1.0 - 1.0 - 0.9583333333333334 MGYG000000743_02099 0.020833333333333332 - - - - 0.9375 0.9375 0.9375 0.9375 - 0.8958333333333334 - 0.8541666666666666 none 1.0 2352666 4033891 1819253 0 2523788 1467319 0 1698875 2309018 1990550 2148809 1327318 0 1665969 2207679 1981481 0 0 2100862 415791 1658350 2199101 1823716 1965568 1660044 0 0 2122447 2669941 1708324 4554575 1850634 2710548 2340319 1318862 1958289 1485022 5032572 1630988 3825662 711496 0 2242742 1420032 2174199 2530462 0 2188615 2509973 0 0 0 0 0 1129318 820040 1515705 1378326 873529 821485 1544616 1856416 1048010 879153 0 1947131 2791990 655581 10336858 2402429 736196 1325377 0 1025991 1339559 1242840 1121447 0 0 0 0 0 663904 0 604693 1563732 0 420685 1091341 0 1364191 1290355 0 0 953467 0 1299062 1222277 0 1982135 0 1390600 1345733 1069279 0 0 0 1971775 2462097 1922517 1525095 0 782658 0 0 0 0 0 516858 705720 3599413 558941 1213123 0 1140560 0 1598664 0 439514 0 527642 279536 643988 0 709631 0 436801 629367 0 328359 555216 664116 0 370031 0 1849629 724096 433499 558825 537121 590983 0 0 6211947 1423222 0 1088589 0 0 0 0 0 0 0 294788 0 1180177 885593 0 0 0 805654 0 810648 1528491 880267 0 0 0 0 0 1797453 1508097 1184090 0 788406 0 1065817 922259 1443318 +AAPAAAPKAAAP MGYG000000200_00817 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp003471165|m__MGYG000000200 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000200_00817 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1899454 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAAPKAAAPK(PS_Hapten)AAPAPK MGYG000000182_00099 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Selenomonadales|f__Selenomonadaceae|g__Mitsuokella|s__Mitsuokella sp003458855|m__MGYG000000182 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000182_00099 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1377494 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAAPKAAPAA MGYG000004769_01105 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_01105 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2149549 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAADFEGSLQQVGNK MGYG000001337_04011 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides fragilis|m__MGYG000001337 1.0 COG1305@1|root,COG1305@2|Bacteria,4NI6P@976|Bacteroidetes,2FPYJ@200643|Bacteroidia,4APBK@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 E 1.0 Domain of Unknown Function with PDB structure (DUF3857) 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DUF3857,DUF3858,Transglut_core 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001337_04011 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 533247 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 710730 0 0 0 0 688095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 199091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 247303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213689 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAGAAGAAAEEK MGYG000002777_00224 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Veillonellales|f__Dialisteraceae|g__Dialister|s__Dialister sp900545785|m__MGYG000002777 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4H4X8@909932|Negativicutes 1.0 909932|Negativicutes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002777_00224 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1061422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAGAGEA(Ala->Val)AAAEK MGYG000002867_00700;MGYG000001562_01082;MGYG000001420_00134;MGYG000003279_00958;MGYG000002203_00881;MGYG000002007_00362;MGYG000004658_01198;MGYG000004756_01180;MGYG000000003_02516 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002867_00700 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAGAGEAAA(Ala->Val)AEK MGYG000002867_00700;MGYG000001562_01082;MGYG000001420_00134;MGYG000003279_00958;MGYG000002203_00881;MGYG000002007_00362;MGYG000004658_01198;MGYG000004756_01180;MGYG000000003_02516 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002867_00700 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1063977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAGAGEAAAAEK MGYG000002867_00700;MGYG000001562_01082;MGYG000001420_00134;MGYG000003279_00958;MGYG000002203_00881;MGYG000002007_00362;MGYG000004658_01198;MGYG000004756_01180;MGYG000000003_02516 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002867_00700 0.1111111111111111 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 1951439 0 678656 1719591 827056 1449641 1486561 1088766 1746362 1367492 615815 1411720 810946 1483853 2088866 1116205 1502558 0 1825958 1628029 1511293 906354 0 1529281 1432481 1725421 1937863 0 1481998 2173247 753735 1189664 710940 1283424 1461995 2075291 1653582 655894 773908 0 840217 737812 496317 690847 521950 629044 142909 821660 453078 1227155 425681 974900 0 0 947758 0 725113 731646 644188 609569 0 0 753639 675981 178705 0 667538 0 525996 751668 713243 0 714791 265443 994452 915208 1031991 0 1244088 697797 858003 468729 735330 772274 998122 781905 566182 710346 705892 1082302 829704 504588 568706 0 566029 869224 1067968 435626 0 335301 507324 800204 778620 0 616759 1156014 468126 297328 642219 1075455 888669 1280163 772739 991036 0 0 388160 168361 200921 290045 418042 464011 547476 493563 415234 350771 512699 276479 703879 0 0 0 603532 383123 461747 560588 0 380908 282181 569274 498810 0 569039 0 0 0 146129 310890 437320 349988 534900 582429 155678 0 254872 201906 274049 230340 380990 252202 353626 0 238957 173279 251217 139372 305878 220581 310197 0 318400 529631 0 250000 0 357764 475856 464910 381548 0 119700 400019 176075 158492 198474 0 532828 386664 194476 214827 +AAPAAGAGEAAVAEK MGYG000000074_01766 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,22UHE@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_01766 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 290947 0 0 0 560181 444340 464303 0 0 495612 424525 0 0 0 0 323896 0 0 0 0 0 0 0 0 0 1638433 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1655090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 433988 0 0 0 0 0 0 0 256124 303922 249280 0 272965 0 0 0 424545 315741 0 0 0 0 509940 0 166443 0 264813 197676 0 408254 204305 0 0 0 0 318705 0 734497 1293881 0 0 0 0 0 0 479054 774917 1253735 0 1127354 1250399 0 0 0 1465116 1343234 0 0 0 0 1782646 0 1106810 0 1130313 1063664 0 1104049 844769 0 1133939 0 0 556667 0 2645523 2824716 0 0 0 0 0 0 4036077 2279904 0 3326431 0 0 3788844 0 0 0 0 3744312 0 0 0 0 0 0 0 2997436 5952128 0 0 3887183 0 0 0 0 0 +AAPAAGAGSIQVK MGYG000001310_00451 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter lactaris|m__MGYG000001310 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_00451 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 1316311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1889083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2350617 0 2545840 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAKPVEAPK MGYG000002961_01600 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900542275|m__MGYG000002961 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,2GJU4@201174|Actinobacteria,4CUBT@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 G 1.0 TIGRFAM PTS system, fructose subfamily, IIC 1.0 - 1.0 - 1.0 2.7.1.202 1.0 ko:K02768,ko:K02769,ko:K02770 1.0 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 1.0 M00273 1.0 R03232 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.2.1 1.0 - 1.0 - 1.0 PTS_EIIA_2,PTS_EIIC,PTS_IIB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002961_01600 1.0 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Phosphotransferase system (PTS) 1.0 K02768:fruB; fructose PTS system EIIA component [EC:2.7.1.202]|K02769:fruAb; fructose PTS system EIIB component [EC:2.7.1.202]|K02770:fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAPAAAPK MGYG000002802_01947;MGYG000000271_00470;MGYG000004271_01071 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia 0.6666666666666666 186801|Clostridia 1.0 I 0.6666666666666666 PFAM biotin lipoyl attachment domain-containing protein 0.6666666666666666 gcdC 0.6666666666666666 - 1.0 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002802_01947 0.3333333333333333 - - - - 0.6666666666666666 0.6666666666666666 0.6666666666666666 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1944183 0 0 0 0 0 0 0 1284400 1053551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1555545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAPAAPK MGYG000000022_01358 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01358 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 791489 0 0 0 0 0 321619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141036 0 0 0 0 0 1730537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372331 0 0 0 0 0 757427 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAPAK MGYG000003266_00143;MGYG000000089_00231 domain d__Bacteria 1.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,2GJU4@201174|Actinobacteria,4CUBT@84998|Coriobacteriia 0.5 84998|Coriobacteriia 0.5 G 0.5 TIGRFAM PTS system, fructose subfamily, IIC 0.5 - 0.5 - 0.5 2.7.1.202 0.5 ko:K02768,ko:K02769,ko:K02770 0.5 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 0.5 M00273 0.5 R03232 0.5 RC00017,RC03206 0.5 ko00000,ko00001,ko00002,ko01000,ko02000 0.5 4.A.2.1 0.5 - 0.5 - 0.5 PTS_EIIA_2,PTS_EIIC,PTS_IIB 0.5 - 0.5 - 0.5 - 0.5 - 0.5 MGYG000003266_00143 0.5 protein-N(pi)-phosphohistidine--D-fructose phosphotransferase. fructose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is usually a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-The enzyme from the bacterium Escherichia coli is an exception, since it is phosphorylated directly by EC 2.7.3.9.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-fructose(out) + N(pros)-phospho-L-histidyl-[protein] = D-fructose 1-phosphate(in) + L-histidyl-[protein]. 0.5 0.5 0.5 0.5 Fructose and mannose metabolism|Metabolic pathways|Microbial metabolism in diverse environments|Phosphotransferase system (PTS) 0.5 K02768:fruB; fructose PTS system EIIA component [EC:2.7.1.202]|K02769:fruAb; fructose PTS system EIIB component [EC:2.7.1.202]|K02770:fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 2518037 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1015030 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAPAQGGIPK MGYG000000171_01275 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3WS7A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Glucose dehydrogenase C-terminus 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_01275 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2235960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAAPK MGYG000000133_01634;MGYG000000022_01358;MGYG000002042_00590 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 I 0.6666666666666666 Biotin-requiring enzyme 0.6666666666666666 gcdC 0.6666666666666666 - 1.0 - 1.0 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 1.0 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 0.6666666666666666 - 1.0 - 1.0 - 1.0 - 0.6666666666666666 MGYG000000133_01634 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 0.6666666666666666 none 1.0 0 0 109590 167682 0 0 0 0 0 0 0 0 0 0 0 0 0 506184 0 0 0 0 347073 0 0 0 0 460852 0 0 0 0 160428 0 0 0 0 352864 0 0 78002 103500 0 0 0 0 0 0 0 0 0 0 0 0 0 140636 0 0 0 0 183736 0 0 0 0 285924 0 0 0 0 73303 0 0 0 0 48703 0 0 114275 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135702 0 0 0 0 161521 0 0 0 0 411353 0 0 0 0 86579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 49704 0 0 0 0 188822 0 0 0 0 0 0 0 0 0 0 0 0 170508 1715944 0 0 0 0 0 0 0 0 0 0 0 0 0 167823 0 0 0 0 240378 0 0 0 0 287449 0 0 0 0 619544 0 0 0 0 0 +AAPADEVAAPAVEAEEGGIHK MGYG000001313_03230 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_03230 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 821842 0 0 0 0 577722 0 0 0 0 642265 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPADPILGLADLFR MGYG000002506_00254;MGYG000003883_00875 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG1448@1|root,COG1448@2|Bacteria,1MUT0@1224|Proteobacteria,1RN02@1236|Gammaproteobacteria,3XNR8@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 E 1.0 L-aspartate:2-oxoglutarate aminotransferase activity 1.0 aspC 1.0 GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.0 2.6.1.1,2.6.1.57 1.0 ko:K00813,ko:K00832 1.0 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 1.0 M00024,M00025,M00034,M00040 1.0 R00355,R00694,R00734,R00896,R01731,R02433,R02619,R05052,R07396,R10845 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 iPC815.YPO1410,iSFxv_1172.SFxv_1000 1.0 Aminotran_1_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_00254 0.5 aspartate transaminase. | aromatic-amino-acid transaminase. transaminase A. Also acts on L-tyrosine, L-phenylalanine and L-tryptophan.-!-This activity can be formed from EC 2.6.1.57 by controlled proteolysis. | L-methionine can also act as donor, more slowly.-!-Oxaloacetate can act as acceptor.-!-Controlled proteolysis converts the enzyme to EC 2.6.1.1. 2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate. | 2-oxoglutarate + an aromatic L-alpha-amino acid = an aromatic oxo-acid + L-glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Alanine, aspartate and glutamate metabolism|Cysteine and methionine metabolism|Arginine and proline metabolism|Tyrosine metabolism|Phenylalanine metabolism|Phenylalanine, tyrosine and tryptophan biosynthesis|Novobiocin biosynthesis|Isoquinoline alkaloid biosynthesis|Tropane, piperidine and pyridine alkaloid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00813:aspC; aspartate aminotransferase [EC:2.6.1.1]|K00832:tyrB; aromatic-amino-acid transaminase [EC:2.6.1.57] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125980 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4396240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAEAPAAE(Glu->Ala)AK MGYG000000301_00933 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900541985|m__MGYG000000301 1.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3Y0FB@572511|Blautia 1.0 186801|Clostridia 1.0 I 1.0 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA 1.0 accB 1.0 - 1.0 - 1.0 ko:K02160 1.0 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 1.0 M00082,M00376 1.0 R00742 1.0 RC00040,RC00367 1.0 ko00000,ko00001,ko00002 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000301_00933 1.0 - - - - 1.0 1.0 1.0 1.0 Fatty acid biosynthesis|Pyruvate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K02160:accB, bccP; acetyl-CoA carboxylase biotin carboxyl carrier protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2944481 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAEEAAAGPSEVTVTLTDVGGTK MGYG000000223_01551 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,36IQP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_01551 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 416453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 780509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371447 0 860895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAGAGAAPAEEKSEFDVVLK MGYG000003022_00741 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella|s__Parasutterella sp000980495|m__MGYG000003022 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,1KKSF@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003022_00741 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 315460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 976030 0 0 0 1353745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAGGAAAPAEEKSEFDVVLK MGYG000003352_00737 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella|s__Parasutterella sp900766055|m__MGYG000003352 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,1KKSF@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003352_00737 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 782243 0 1652754 848607 0 0 0 0 0 839175 0 0 0 0 0 0 646938 0 407773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1002257 0 1121083 1004621 0 0 0 0 0 545985 0 0 0 0 0 0 534833 0 435953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAGGAGSIEVK MGYG000002279_00505;MGYG000002992_01786 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,27VPV@189330|Dorea 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_00505 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1092491 0 0 0 1511548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1978193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPALLEPIMK MGYG000000562_01882;MGYG000000187_02028 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,25VFH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000000562_01882 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1145501 0 0 0 0 1118856 0 0 0 0 1377932 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 336124 0 0 0 0 271763 0 0 0 0 321613 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 771251 0 0 0 0 922247 0 0 0 0 1020160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1510336 0 0 0 0 1022316 0 0 0 0 1770142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 721791 0 0 0 0 1013355 0 0 0 0 1128792 0 0 0 0 0 0 0 0 0 0 +AAPANIK MGYG000000271_02509;MGYG000004271_00777 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000271_02509 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 1179468 0 0 0 0 999349 0 0 864221 0 697875 1039782 0 543886 0 0 1108181 0 0 0 0 1196121 0 1011414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350237 0 0 0 0 84913 0 0 101441 0 416564 38017 0 0 0 0 218246 0 0 0 0 312732 0 298951 0 0 0 0 0 0 0 0 0 0 0 0 0 0 31922 0 0 0 0 0 0 0 111863 0 73869 0 0 128184 0 0 0 0 0 0 0 67706 0 47630 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 142308 0 0 64116 0 203734 0 0 407156 0 0 40785 0 0 0 0 0 0 248304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 682288 0 0 0 0 1234724 0 0 757793 0 521851 529862 0 611749 0 0 748376 0 0 0 0 341466 0 470038 0 0 0 0 0 0 0 0 +AAPAPAAAAAPAAPAAPASAGAVEVK MGYG000002545_00187 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_G|m__MGYG000002545 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002545_00187 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 666863 0 0 0 0 609216 0 0 0 0 607579 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 288426 0 0 0 0 310216 0 0 0 0 344267 0 0 0 0 0 0 0 0 0 0 +AAPAPAAAPAPA(Ala->Pro)AK MGYG000002535_03464 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter|s__Citrobacter gillenii|m__MGYG000002535 1.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,3WWKR@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 C 1.0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) 1.0 aceF 1.0 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 1.0 2.3.1.12 1.0 ko:K00627 1.0 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 1.0 M00307 1.0 R00209,R02569 1.0 RC00004,RC02742,RC02857 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iETEC_1333.ETEC_0111,iSSON_1240.SSON_0123,iYL1228.KPN_00119 1.0 2-oxoacid_dh,Biotin_lipoyl,E3_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002535_03464 1.0 dihydrolipoyllysine-residue acetyltransferase. transacetylase X. A multimer (24-mer or 60-mer, depending on the source) of this enzyme forms the core of the pyruvate dehydrogenase multienzyme complex, and binds tightly both EC 1.2.4.1 and EC 1.8.1.4.-!-The lipoyl group of this enzyme is reductively acetylated by EC 1.2.4.1, and the only observed direction catalyzed by EC 2.3.1.12 is that where the acetyl group is passed to coenzyme A. acetyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = CoA + N(6)- [(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00627:DLAT, aceF, pdhC; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAPAAAPAPAA(Ala->Pro)K MGYG000002535_03464 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter|s__Citrobacter gillenii|m__MGYG000002535 1.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,3WWKR@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 C 1.0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) 1.0 aceF 1.0 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 1.0 2.3.1.12 1.0 ko:K00627 1.0 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 1.0 M00307 1.0 R00209,R02569 1.0 RC00004,RC02742,RC02857 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iETEC_1333.ETEC_0111,iSSON_1240.SSON_0123,iYL1228.KPN_00119 1.0 2-oxoacid_dh,Biotin_lipoyl,E3_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002535_03464 1.0 dihydrolipoyllysine-residue acetyltransferase. transacetylase X. A multimer (24-mer or 60-mer, depending on the source) of this enzyme forms the core of the pyruvate dehydrogenase multienzyme complex, and binds tightly both EC 1.2.4.1 and EC 1.8.1.4.-!-The lipoyl group of this enzyme is reductively acetylated by EC 1.2.4.1, and the only observed direction catalyzed by EC 2.3.1.12 is that where the acetyl group is passed to coenzyme A. acetyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = CoA + N(6)- [(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00627:DLAT, aceF, pdhC; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2488480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAPAAAPAPAPA(Ala->Lys) MGYG000000255_00870;MGYG000000205_00592 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,2208C@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 CBM50 1.0 - 1.0 MGYG000000255_00870 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2455535 0 0 0 0 0 0 0 0 0 1911151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAPAAAPAPK MGYG000001365_01216;MGYG000004769_00268 family d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001365_01216 0.5 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 909693 0 0 916905 0 0 0 0 667287 0 0 0 0 1288321 0 0 0 0 367459 474494 1065774 0 0 0 574037 469589 802560 0 0 575224 0 0 0 677995 566680 259676 321810 0 18052349 19846840 20890174 16004057 19284352 15518796 12971788 21176603 17542681 19450618 18963070 18966400 12950751 19843125 15903901 17060039 19237805 0 15848609 13275021 14747615 17319285 2622997 14835963 16530550 15780139 14371315 0 18567643 15598349 15422437 18474061 20261970 18890794 22998959 15918256 15762328 19071993 8805370 8302296 9718059 6379610 10463716 9881268 9225966 10936012 6817522 8558725 11911688 6763841 11768415 6872345 7930981 6778824 3966291 4797420 8059555 7402540 7117635 7615092 4015931 8896433 8447506 8627623 7727077 4092802 7584098 6839687 10840610 7189239 7295768 9910621 13303949 8280634 8657312 5070131 1377866 1320346 2673942 1313841 1556919 1231593 1519812 1870515 1209114 1424781 1698613 1422342 2206615 982341 1349537 1053347 1101240 0 1589764 911982 1421154 1826566 247769 1723352 1161478 1211417 1175458 0 1263064 1550486 1714665 1659568 2825467 1526833 1781046 1486166 1291760 1999061 0 0 14296024 17377723 12446038 15216731 6985764 17389097 11636364 6714867 12568319 9729893 16375206 7532711 9550585 6748232 9620448 16453464 10008684 9347183 6815030 7903166 20517271 16673268 14518802 12931639 0 14727055 7098084 9920244 15309053 19944331 10535200 10144122 15526504 13547464 10343675 16716865 +AAPAPAAAPAPKA(Ala->Pro)A MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_00268 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2427056 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1943135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAPAAAPAPKAA(Ala->Pro) MGYG000004769_00268 genome d__Bacteria|p__Firmicutes_C|c__Negativicutes|o__Acidaminococcales|f__Acidaminococcaceae|g__Phascolarctobacterium|s__Phascolarctobacterium faecium|m__MGYG000004769 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,4H5DY@909932|Negativicutes 1.0 909932|Negativicutes 1.0 I 1.0 glutaconyl-CoA decarboxylase subunit gamma 1.0 gcdC 1.0 - 1.0 4.1.1.70 1.0 ko:K01615 1.0 ko00362,ko00650,ko01120,map00362,map00650,map01120 1.0 - 1.0 R03028 1.0 RC00832 1.0 ko00000,ko00001,ko01000,ko02000 1.0 3.B.1.1.3 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004769_00268 1.0 glutaconyl-CoA decarboxylase. pent-2-enoyl-CoA carboxy-lyase. The enzyme from the bacterium Acidaminococcus fermentans is a biotinyl-protein, requires Na(+), and acts as a sodium pump.-!-Prior to the Na(+)-dependent decarboxylation, the carboxylate is transferred to biotin in a Na(+)-independent manner.-!-The conserved lysine, to which biotin forms an amide bond, is located 34 amino acids before the C-terminus, flanked on both sides by two methionine residues, which are conserved in every biotin-dependent enzyme.-!-Formerly EC 4.1.1.70. (2E)-glutaconyl-CoA + H(+) + Na(+)(in) = (2E)-butenoyl-CoA + CO2 + Na(+)(out). 1.0 1.0 1.0 1.0 Benzoate degradation|Butanoate metabolism|Microbial metabolism in diverse environments 1.0 K01615:gcdA; glutaconyl-CoA decarboxylase subunit alpha [EC:7.2.4.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3240781 0 0 0 0 0 4117581 2717795 0 0 0 0 0 0 0 0 0 0 0 1833154 0 0 0 0 0 0 2542424 0 0 0 0 2165358 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 162091 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAPAAAPAQAAKPAAAPAAK MGYG000002494_03015 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0508@1|root,COG0508@2|Bacteria,1MU7K@1224|Proteobacteria,1RNPT@1236|Gammaproteobacteria,3ZJ1Q@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 C 1.0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) 1.0 aceF 1.0 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 1.0 2.3.1.12 1.0 ko:K00627 1.0 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 1.0 M00307 1.0 R00209,R02569 1.0 RC00004,RC02742,RC02857 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iETEC_1333.ETEC_0111,iSSON_1240.SSON_0123,iYL1228.KPN_00119 1.0 2-oxoacid_dh,Biotin_lipoyl,E3_binding 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03015 1.0 dihydrolipoyllysine-residue acetyltransferase. transacetylase X. A multimer (24-mer or 60-mer, depending on the source) of this enzyme forms the core of the pyruvate dehydrogenase multienzyme complex, and binds tightly both EC 1.2.4.1 and EC 1.8.1.4.-!-The lipoyl group of this enzyme is reductively acetylated by EC 1.2.4.1, and the only observed direction catalyzed by EC 2.3.1.12 is that where the acetyl group is passed to coenzyme A. acetyl-CoA + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] = CoA + N(6)- [(R)-S(8)-acetyldihydrolipoyl]-L-lysyl-[protein]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00627:DLAT, aceF, pdhC; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572797 0 338033 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAPAAAPK MGYG000000076_00252;MGYG000003291_00824;MGYG000001300_00242;MGYG000001417_02207;MGYG000000245_00298;MGYG000003166_01306 domain d__Bacteria 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 0.5 186801|Clostridia 0.8333333333333334 I 0.8333333333333334 Biotin-requiring enzyme 0.5 gcdC 0.8333333333333334 - 1.0 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 0.8333333333333334 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000076_00252 0.16666666666666666 - - - - 0.8333333333333334 0.8333333333333334 0.8333333333333334 0.8333333333333334 - 0.8333333333333334 - 0.8333333333333334 none 1.0 1537241 0 1273853 1837800 0 879713 1328296 799017 0 0 0 1335687 1302963 1819746 1154285 911605 1026724 0 0 1571500 1189510 1113319 0 1419428 1212716 1637593 0 0 0 0 0 0 1602975 0 0 0 1471414 1442151 0 0 8497305 14375672 0 10351660 16623734 6450414 11744471 0 0 10667918 8800435 14380920 12160188 0 0 0 16105568 11605120 5860166 8426729 0 8635780 15035437 12760702 0 0 0 0 0 0 13056900 0 0 0 13970987 7650731 823223 0 1425618 1278893 0 546859 1757610 1171745 1209737 0 0 1146150 1363718 978361 1164063 1038503 752229 0 1307863 0 0 2768896 0 3136230 1637645 1388391 0 0 0 1121811 0 0 1318834 1343831 0 0 1004724 1297959 5677317 0 0 6057363 0 9212553 9420397 4037311 7366955 0 0 15888296 7570956 7000641 8047576 7000840 6369678 0 12667117 6724186 3089744 13602412 0 12808506 6668475 6648246 0 0 0 6510243 0 0 9562672 15824044 0 0 6849434 9096690 0 0 134832 0 0 0 212382 113148 0 0 0 0 0 0 0 0 200877 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230071 +AAPAPAAAPKAAAGAAGAVAVK MGYG000001300_00242 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00242 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754078 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAPAAK MGYG000002506_04250;MGYG000004769_00268 domain d__Bacteria 1.0 COG2609@1|root,COG2609@2|Bacteria,1MV21@1224|Proteobacteria,1RN6K@1236|Gammaproteobacteria,3XP9X@561|Escherichia 0.5 1236|Gammaproteobacteria 0.5 F 0.5 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) 0.5 aceE 0.5 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 0.5 1.2.4.1 0.5 ko:K00163 0.5 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 0.5 M00307 0.5 R00014,R00209,R01699,R03270 0.5 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 0.5 br01601,ko00000,ko00001,ko00002,ko01000 0.5 - 0.5 - 1.0 e_coli_core.b0114,iAF1260.b0114,iBWG_1329.BWG_0107,iE2348C_1286.E2348C_0117,iEC55989_1330.EC55989_0107,iECDH10B_1368.ECDH10B_0094,iECDH1ME8569_1439.ECDH1ME8569_0108,iECH74115_1262.ECH74115_0121,iECIAI1_1343.ECIAI1_0112,iECNA114_1301.ECNA114_0106,iECO103_1326.ECO103_0114,iECO111_1330.ECO111_0115,iECO26_1355.ECO26_0116,iECSE_1348.ECSE_0114,iECSF_1327.ECSF_0127,iECSP_1301.ECSP_0115,iECUMN_1333.ECUMN_0111,iECW_1372.ECW_m0111,iECs_1301.ECs0118,iEKO11_1354.EKO11_3802,iETEC_1333.ETEC_0110,iEcDH1_1363.EcDH1_3488,iEcE24377_1341.EcE24377A_0116,iEcHS_1320.EcHS_A0118,iEcSMS35_1347.EcSMS35_0124,iEcolC_1368.EcolC_3545,iG2583_1286.G2583_0118,iJO1366.b0114,iJR904.b0114,iUMNK88_1353.UMNK88_112,iWFL_1372.ECW_m0111,iY75_1357.Y75_RS00580,iZ_1308.Z0124 0.5 Transketolase_N 0.5 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04250 0.5 pyruvate dehydrogenase (acetyl-transferring). pyruvic dehydrogenase. It is a component (in multiple copies) of EC 1.2.1.104 in which it is bound to a core of molecules of EC 2.3.1.12, which also binds multiple copies of EC 1.8.1.4.-!-It does not act on free lipoamide or lipoyllysine, but only on the lipoyllysine residue in EC 2.3.1.12. H(+) + N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + pyruvate = CO2 + N(6)-[(R)-S(8)- acetyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase]. 0.5 0.5 0.5 0.5 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 0.5 K00163:aceE; pyruvate dehydrogenase E1 component [EC:1.2.4.1] 0.5 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1947971 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1119680 0 0 0 2486321 1342470 1102048 1133960 0 0 0 0 0 0 0 0 0 0 1748983 0 0 0 0 0 0 0 0 0 0 0 0 1830492 0 0 431650 532667 0 1226833 240689 0 906438 0 0 1146344 0 0 0 0 0 1291506 0 0 491302 0 1259190 0 0 0 808626 540461 820275 0 0 0 0 871396 0 1069154 402715 0 0 0 0 0 0 0 0 763105 0 517774 0 622172 0 861220 0 0 0 924927 0 0 0 0 499986 0 0 0 0 0 0 0 0 0 0 0 0 694822 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAPAAPAAPK MGYG000002224_01088 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium sp900540455|m__MGYG000002224 1.0 COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3WK2X@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 I 1.0 Biotin-requiring enzyme 1.0 gcdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 CBM50 1.0 - 1.0 MGYG000002224_01088 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8732044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 6584726 0 0 0 0 0 0 0 0 0 0 0 +AAPAPAPK MGYG000000133_01634;MGYG000001365_01216;MGYG000001577_01926;MGYG000000053_01133;MGYG000003926_00723 domain d__Bacteria 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,22UXN@171550|Rikenellaceae 0.4 186801|Clostridia 0.4 J 0.6 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 0.6 infB 0.6 - 1.0 - 0.8 ko:K02519 0.6 - 0.8 - 1.0 - 0.8 - 0.8 ko00000,ko03012,ko03029 0.6 - 0.8 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 0.6 - 1.0 - 1.0 - 1.0 GT2 0.6 MGYG000000133_01634 0.2 - - - - 0.8 0.8 0.8 0.8 - 0.8 K02519:infB, MTIF2; translation initiation factor IF-2 0.6 none 1.0 0 49091 0 0 0 0 0 0 0 0 0 0 0 49863 0 0 0 0 0 60061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53599 267385 185006 221950 124332 323546 186387 299598 419702 255476 192032 723909 296529 317674 114077 101682 263045 267909 0 286797 142190 172758 154878 0 115297 196840 248034 269499 0 266430 0 337808 226854 210979 73286 306667 73197 142691 297502 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 88789 59375 0 94825 0 0 0 0 39631 83554 0 0 0 106918 0 0 53987 0 0 0 0 0 0 52854 116793 0 0 0 0 0 65606 0 0 69355 55162 10970080 10643197 12960950 12907123 4140507 8086282 17275590 9361085 8490178 11104301 12473277 14516065 4745057 16594845 10112355 5006881 7514590 6563496 5295563 4961520 20551395 6097035 4951176 8873174 8379798 8221942 12913066 2548567 13760939 3491259 9483563 6479787 20225703 7715670 16829591 9985680 7375590 9984787 +AAPAPVAAPK MGYG000002494_03382 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1RHH7@1224|Proteobacteria,1RNAT@1236|Gammaproteobacteria,3WY36@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 PTS system sorbose subfamily IIB component 1.0 manX 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006793,GO:0006796,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0008645,GO:0008982,GO:0009401,GO:0009987,GO:0015144,GO:0015145,GO:0015149,GO:0015578,GO:0015749,GO:0015761,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0022870,GO:0031224,GO:0031226,GO:0034219,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046323,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098657,GO:0098704,GO:0098708,GO:0098739,GO:1904659 1.0 2.7.1.191 1.0 ko:K02793,ko:K02794 1.0 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 1.0 M00276 1.0 R02630 1.0 RC00017,RC03206 1.0 ko00000,ko00001,ko00002,ko01000,ko02000 1.0 4.A.6.1 1.0 - 1.0 iAPECO1_1312.APECO1_874,iECOK1_1307.ECOK1_1934,iECS88_1305.ECS88_1869,iPC815.YPO1758,iUMN146_1321.UM146_08085,iUTI89_1310.UTI89_C2014 1.0 EIIA-man,PTSIIB_sorb 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03382 1.0 protein-N(pi)-phosphohistidine--D-mannose phosphotransferase. mannose PTS permease. This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS).-!-The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it.-!-The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC 2.7.3.9.-!-Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency.-!-The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.-!-Formerly EC 2.7.1.69. D-mannose(out) + N(pros)-phospho-L-histidyl-[protein] = D-mannose 6-phosphate(in) + L-histidyl-[protein]. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Phosphotransferase system (PTS) 1.0 K02793:manXa; mannose PTS system EIIA component [EC:2.7.1.191]|K02794:manX; mannose PTS system EIIAB component [EC:2.7.1.191] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1922204 0 0 0 0 3923194 2168039 0 2049663 0 0 0 0 0 0 0 0 0 2926765 0 0 4729629 0 3516597 0 1374628 0 0 3123279 0 0 0 0 0 0 0 2052137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 135131 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103298 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAQIK MGYG000001711_01335 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__Holdemanella|s__Holdemanella biformis|m__MGYG000001711 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,3VNYH@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001711_01335 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 937508 0 0 0 0 0 0 0 0 0 1004929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 653050 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 104456 0 0 0 0 0 0 0 0 0 259285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAQTEQTTEAAVVEEGGGLHK MGYG000004797_01477 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sartorii|m__MGYG000004797 1.0 COG0811@1|root,COG0811@2|Bacteria,4NEA2@976|Bacteroidetes,2FMMQ@200643|Bacteroidia,4AN3A@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 U 1.0 MotA TolQ ExbB proton channel family 1.0 exbB 1.0 - 1.0 - 1.0 ko:K03561 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 1.A.30.2.1 1.0 - 1.0 - 1.0 MotA_ExbB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_01477 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03561:exbB; biopolymer transport protein ExbB 1.0 none 1.0 0 0 0 0 0 0 448943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1291117 0 0 0 0 0 0 0 0 0 0 0 0 0 5801260 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2890886 0 0 0 0 0 0 0 0 0 0 0 0 0 4064637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7779289 0 0 0 0 0 0 0 0 0 0 0 0 0 4323978 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1769547 0 0 0 0 0 0 0 0 0 0 0 0 0 602041 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPATEGQFGDDITMASWK MGYG000002517_01844 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1143@1|root,COG4624@1|root,COG1143@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Iron only hydrogenase large subunit, C-terminal domain 1.0 - 1.0 - 1.0 1.12.7.2 1.0 ko:K00533 1.0 - 1.0 - 1.0 R00019 1.0 - 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fe_hyd_lg_C,Fer4,Fer4_6,Fer4_7 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01844 1.0 ferredoxin hydrogenase. uptake hydrogenase. Can use molecular hydrogen for the reduction of a variety of substances.-!-Formerly EC 1.12.1.1, EC 1.12.7.1, EC 1.18.3.1, EC 1.18.99.1 and EC 1.98.1.1. H2 + 2 oxidized [2Fe-2S]-[ferredoxin] = 2 H(+) + 2 reduced [2Fe-2S]- [ferredoxin]. 1.0 1.0 1.0 1.0 - 1.0 K00533:E1.12.7.2L; ferredoxin hydrogenase large subunit [EC:1.12.7.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1100462 1221955 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPAVATK MGYG000001300_02529 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG3940@1|root,COG3940@2|Bacteria,1VAX9@1239|Firmicutes,24NY2@186801|Clostridia,3WKE6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Ricin-type beta-trefoil 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 RicinB_lectin_2 1.0 - 1.0 CBM13 1.0 CBM13 1.0 CBM13 1.0 MGYG000001300_02529 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 119658 0 0 0 0 0 87590 0 0 0 0 0 0 0 0 0 0 0 301502 1015657 0 0 0 0 0 242147 0 0 0 0 0 0 0 0 0 0 67381 0 505043 0 0 0 0 0 1285598 0 0 0 0 0 0 0 0 0 0 0 1114687 539063 0 0 0 0 0 643717 0 0 0 0 0 0 0 0 0 0 559585 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84396 0 0 0 0 0 0 0 0 0 0 82144 0 0 0 0 0 0 0 303151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90234 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPDNMK MGYG000002492_01331;MGYG000000262_01692 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 0.5 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002492_01331 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 111944 0 0 0 0 0 0 0 346165 0 0 0 0 0 0 0 393300 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 839999 0 0 0 0 481684 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPDNMKVADTK MGYG000000262_01692 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,25USH@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000262_01692 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 514580 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 868223 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPDQPK MGYG000002469_01094;MGYG000001292_01123 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,4CZ64@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Belongs to the transketolase family 1.0 tkt 1.0 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 TAL_FSA,Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002469_01094 0.5 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 133041 0 0 0 0 122248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPEITR MGYG000002477_01229;MGYG000002494_02707;MGYG000002534_04377;MGYG000000235_02908 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0330@1|root,COG0330@2|Bacteria,1MUM2@1224|Proteobacteria,1RMUG@1236|Gammaproteobacteria,3WVEI@544|Citrobacter 0.75 1236|Gammaproteobacteria 1.0 O 1.0 HflC and HflK could encode or regulate a protease 1.0 hflK 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 1.0 - 1.0 ko:K04088 1.0 - 1.0 M00742 1.0 - 1.0 - 1.0 ko00000,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Band_7,HflK_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002477_01229 0.25 - - - - 1.0 1.0 1.0 1.0 - 1.0 K04088:hflK; modulator of FtsH protease HflK 1.0 none 1.0 0 164049 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 938991 0 0 648339 0 0 0 0 0 0 0 0 0 0 0 0 0 899427 0 0 0 0 0 0 0 0 0 0 0 0 483583 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPELM(Oxidation)PTAEQR MGYG000004271_02489;MGYG000000271_01599 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Radical SAM domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,Radical_SAM,SPASM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_02489 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPELMPTAEQR MGYG000004271_02489;MGYG000000271_01599 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Radical SAM domain protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Fer4_12,Fer4_14,Radical_SAM,SPASM 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_02489 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPGAAAGGAAAEEK MGYG000004704_00527 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella|s__|m__MGYG000004704 1.0 COG0222@1|root,COG0222@2|Bacteria,1RGU4@1224|Proteobacteria,2VSG7@28216|Betaproteobacteria,4PR0T@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004704_00527 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1337463 0 0 0 0 0 +AAPGLTGFTK MGYG000001300_00048;MGYG000001761_00345;MGYG000002272_01119;MGYG000003937_02082;MGYG000004679_00432;MGYG000000022_01588;MGYG000003899_01912;MGYG000002040_02064;MGYG000004700_00143;MGYG000000084_00427;MGYG000003921_00872;MGYG000004866_00913;MGYG000001255_01742 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3WGDG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 E 1.0 Branched-chain amino acid aminotransferase 1.0 ilvE 1.0 - 1.0 2.6.1.42,4.1.3.38 1.0 ko:K00826,ko:K02619 1.0 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R05553,R10991 1.0 RC00006,RC00036,RC01843,RC02148 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_00048 0.07692307692307693 branched-chain-amino-acid transaminase. | aminodeoxychorismate lyase. transaminase B. | enzyme X. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. | Forms part of the folate biosynthesis pathway.-!-Acts on 4-amino-4-deoxychorismate, the product of EC 2.6.1.85, to form p-aminobenzoate. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. | 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Valine, leucine and isoleucine degradation|Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Folate biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00826:E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]|K02619:pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38] 1.0 none 1.0 0 0 0 0 0 0 1239270 0 0 2084247 2670132 0 0 0 0 0 0 4674808 2250194 0 0 0 4051657 0 0 0 0 4405135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 901497 0 0 0 0 0 0 0 0 0 0 0 793184 0 0 0 0 0 0 0 0 4087885 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 292938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2264884 0 0 1640904 1969860 0 0 0 0 0 0 0 1687460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5927277 771522 0 0 0 6844261 0 0 0 0 6133136 0 0 0 0 0 0 0 0 0 0 +AAPGYYMAK MGYG000001300_01368;MGYG000000022_00954;MGYG000002040_00422;MGYG000003899_01851;MGYG000004679_00269 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WHEI@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties 1.0 glgP 1.0 - 1.0 2.4.1.1 1.0 ko:K00688 1.0 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 1.0 - 1.0 R02111 1.0 - 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GT35 1.0 - 1.0 DUF3417,Phosphorylase 1.0 2.4.1.1 1.0 GT35 1.0 GT35 1.0 GT35 1.0 MGYG000001300_01368 0.2 glycogen phosphorylase. polyphosphorylase. This entry covers several enzymes from different sources that act in vivo on different forms of (1->4)-alpha-D-glucans.-!-Some of these enzymes catalyze the first step in the degradation of large branched glycan polymers - the phosphorolytic cleavage of alpha-1,4-glucosidic bonds from the non-reducing ends of linear poly(1->4)-alpha-D-glucosyl chains within the polymers.-!-The enzyme stops when it reaches the fourth residue away from an alpha-1,6 branching point, leaving a highly branched core known as a limit dextrin.-!-The description (accepted name) of the enzyme should be modified for each specific instance by substituting 'glycogen' with the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, etc. [(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate. 1.0 1.0 1.0 1.0 Starch and sucrose metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Biofilm formation - Escherichia coli|Necroptosis|Insulin signaling pathway|Glucagon signaling pathway|Insulin resistance 1.0 K00688:PYG, glgP; glycogen phosphorylase [EC:2.4.1.1] 1.0 none 1.0 1064097 0 1025925 1014079 0 891870 642033 0 652495 0 0 0 0 0 0 0 0 1659200 905350 0 0 758946 1100093 648980 0 743910 0 1788433 0 0 0 0 858737 0 0 0 714367 1019221 1158387 0 913274 1657852 0 848758 1448265 0 1216323 0 0 0 0 0 0 0 0 1086245 1495190 0 0 574535 1655758 694361 0 1020127 0 1436341 0 0 0 0 967509 0 0 0 990439 893641 565959 0 328405 190883 0 306406 401587 0 501939 0 0 0 0 0 0 0 0 934313 318626 0 0 276060 946003 373226 0 348323 0 975252 0 0 0 0 319632 0 0 0 452628 0 527897 0 467989 476873 0 737132 528426 0 580408 0 0 0 0 0 0 0 0 381967 514612 0 0 849484 266685 662398 0 560813 0 353507 0 0 0 0 641725 0 0 0 329230 755556 258141 0 226046 201956 0 0 290819 0 0 0 0 0 0 0 0 0 0 797897 229408 0 0 138071 1095810 372967 0 0 0 1054777 0 0 0 0 220669 0 0 0 0 154678 +AAPHGTGHIK MGYG000000133_00291;MGYG000002492_02170;MGYG000000489_00852;MGYG000001338_00230 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3XZFI@572511|Blautia 0.5 186801|Clostridia 1.0 EH 0.5 Psort location Cytoplasmic, score 8.87 0.5 ilvE 1.0 - 1.0 2.6.1.42,4.1.3.38 1.0 ko:K00826,ko:K02619 1.0 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R05553,R10991 1.0 RC00006,RC00036,RC01843,RC02148 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00291 0.25 branched-chain-amino-acid transaminase. | aminodeoxychorismate lyase. transaminase B. | enzyme X. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. | Forms part of the folate biosynthesis pathway.-!-Acts on 4-amino-4-deoxychorismate, the product of EC 2.6.1.85, to form p-aminobenzoate. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. | 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Valine, leucine and isoleucine degradation|Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Folate biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00826:E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]|K02619:pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 147915 0 0 0 0 64712 0 0 0 0 13985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 190483 0 0 0 0 365601 0 0 0 0 46317 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 75531 0 0 0 0 0 10019 0 0 0 0 226477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11969 0 0 0 0 80141 0 0 0 0 24436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 246696 43312 0 0 0 0 21453 0 0 0 0 172221 0 0 0 0 0 0 0 0 0 0 +AAPHGTGIYK MGYG000001337_04196;MGYG000000013_03135;MGYG000000196_04103;MGYG000001345_01382;MGYG000001378_03184 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,2FMPE@200643|Bacteroidia,4AMTS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase 1.0 ilvE 1.0 - 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001337_04196 0.2 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Valine, leucine and isoleucine degradation|Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00826:E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42] 1.0 none 1.0 668074 0 0 661893 0 450385 0 0 0 0 892852 0 0 0 0 0 0 0 0 0 0 421177 0 811686 0 573218 0 0 0 0 0 0 0 712244 0 0 445868 0 543894 0 0 801107 0 727329 0 0 0 0 1147300 0 0 0 0 0 0 0 0 0 0 748945 0 576778 0 425081 0 0 0 0 0 0 0 460768 0 0 890870 0 268611 0 0 227783 0 143622 0 0 0 0 485869 0 0 0 0 0 0 0 0 0 0 187775 0 472942 0 370214 0 0 0 0 0 0 0 366156 0 0 112044 0 592601 0 0 414784 0 520286 0 0 0 0 798692 0 0 0 0 0 0 0 0 0 0 456949 0 0 0 484361 0 0 0 0 0 0 0 620536 0 0 637956 0 561999 0 0 231270 0 342146 0 0 0 0 848155 0 0 0 0 0 0 0 0 0 0 583001 0 985783 0 710058 0 0 0 0 0 0 0 586644 0 0 428268 0 +AAPHGTGNIK MGYG000001319_00809 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Butyrivibrio_A|s__Butyrivibrio_A crossotus|m__MGYG000001319 1.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,4BWI7@830|Butyrivibrio 1.0 186801|Clostridia 1.0 EH 1.0 Amino-transferase class IV 1.0 ilvE 1.0 - 1.0 2.6.1.42,4.1.3.38 1.0 ko:K00826,ko:K02619 1.0 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R05553,R10991 1.0 RC00006,RC00036,RC01843,RC02148 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001319_00809 1.0 branched-chain-amino-acid transaminase. | aminodeoxychorismate lyase. transaminase B. | enzyme X. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. | Forms part of the folate biosynthesis pathway.-!-Acts on 4-amino-4-deoxychorismate, the product of EC 2.6.1.85, to form p-aminobenzoate. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. | 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Valine, leucine and isoleucine degradation|Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Folate biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00826:E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]|K02619:pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 714230 0 0 0 0 859444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 99092 0 0 0 0 62706 0 0 0 0 249606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 114142 0 0 0 0 272363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 58533 0 0 0 0 0 0 0 0 0 254112 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 126305 0 0 0 0 0 0 0 0 0 0 +AAPHLDG(Gly->Ser)SYAAFGK MGYG000000133_02803;MGYG000000301_01800 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides 1.0 ppiB 1.0 - 1.0 5.2.1.8 1.0 ko:K03768 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Pro_isomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02803 0.5 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K03768:PPIB, ppiB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 974293 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPHLDGAYAAFGK MGYG000003335_00657;MGYG000000251_00957 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia 0.5 186801|Clostridia 1.0 O 1.0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides 1.0 ppiB 1.0 - 1.0 5.2.1.8 1.0 ko:K03768 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Pro_isomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003335_00657 0.5 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K03768:PPIB, ppiB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 413782 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1040913 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161811 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPHLDGEYAAFGK MGYG000000077_01045;MGYG000000262_01678 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum 1.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,25W2U@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 O 1.0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides 1.0 ppiB 1.0 - 1.0 5.2.1.8 1.0 ko:K03768 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Pro_isomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000077_01045 0.5 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K03768:PPIB, ppiB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] 1.0 none 1.0 0 0 0 79157 0 230985 0 0 0 0 0 0 0 0 0 0 279579 0 0 0 0 442217 0 300666 240501 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 213177 0 256651 0 0 0 0 0 0 0 0 0 0 309949 0 0 0 0 326931 0 381855 307408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 840245 0 868148 0 0 0 0 0 0 0 0 0 0 420704 0 0 0 0 732554 0 836225 739416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 560843 0 467384 0 0 0 0 0 0 0 0 0 0 562386 0 0 0 0 425898 0 126916 339982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 96079 0 326321 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471215 0 343537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPHLDGQYAAFGK MGYG000000028_00332;MGYG000002528_01778 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,268D2@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 O 1.0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides 1.0 ppiB 1.0 - 1.0 5.2.1.8 1.0 ko:K03768 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Pro_isomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000028_00332 0.5 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K03768:PPIB, ppiB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] 1.0 none 1.0 0 199010 0 0 0 196988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 230599 0 0 0 0 0 97381 233390 0 0 0 0 0 0 0 0 0 0 1137978 0 0 0 703719 0 0 0 0 0 0 0 0 0 0 0 484928 141766 0 0 758559 519747 975684 0 0 0 500046 266693 0 0 439453 0 0 0 0 0 0 0 2932127 0 0 0 1411967 0 0 0 0 0 0 0 0 0 0 0 219860 1006685 0 0 3797541 527347 1249991 0 0 0 850482 2429317 0 0 3261207 0 0 0 0 0 0 0 703850 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1009113 0 0 841791 0 0 0 0 0 0 0 1554182 0 0 0 1471507 0 0 0 0 0 0 0 0 0 0 0 0 642911 0 0 781108 0 1832870 0 0 0 0 1334307 0 0 0 0 0 0 0 0 0 +AAPHLDGSYAAFGK MGYG000000133_02803;MGYG000000301_01800 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia 1.0 186801|Clostridia 1.0 O 1.0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides 1.0 ppiB 1.0 - 1.0 5.2.1.8 1.0 ko:K03768 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko03110 1.0 - 1.0 - 1.0 - 1.0 Pro_isomerase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02803 0.5 peptidylprolyl isomerase. rotamase. The first type of this enzyme found proved to be the protein cyclophilin, which binds the immunosuppressant cyclosporin A.-!-Other distinct families of the enzyme exist, one being FK-506 binding proteins (FKBP) and another that includes parvulin from Escherichia coli.-!-The three families are structurally unrelated and can be distinguished by being inhibited by cyclosporin A, FK-506 and 5-hydroxy-1,4-naphthoquinone, respectively. [protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0). 1.0 1.0 1.0 1.0 - 1.0 K03768:PPIB, ppiB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] 1.0 none 1.0 591045 316695 384479 181515 0 666840 279709 506967 469507 502020 629524 378966 932838 801629 665212 424183 387522 0 613641 0 350637 434431 0 534646 385155 761029 571828 0 888774 0 585582 544711 343087 715487 459767 634570 158498 536486 507925 327182 126089 69131 0 154200 477333 340427 215532 432656 199402 0 247316 0 85652 0 0 0 86911 0 195114 80896 0 163467 321458 212755 0 0 481015 0 150594 220655 278029 73444 233826 0 84564 244546 569486 330184 370234 305721 0 560133 147422 460145 307142 439613 242356 361901 289066 299743 428878 369718 323099 0 423816 0 269268 598872 0 0 493278 415398 416674 0 405383 0 441439 452979 456553 311283 452103 303000 437260 256702 108312 0 433659 0 0 0 332505 0 101030 368938 0 0 74535 0 0 0 0 0 136012 0 0 0 0 0 0 0 262025 0 576858 0 85338 0 0 0 0 0 0 0 2421596 2728622 3294267 4427968 0 1914749 3994029 2193843 1979937 3551036 3448707 2642897 3290369 3872496 2272507 2199051 2787927 0 2857002 0 3561200 2434955 0 3261867 2996106 2555886 2776381 0 3995621 0 2220366 3999061 4240984 2543751 1660642 2263324 1827283 1856461 +AAPIKPEVSFDDFEKLDIR MGYG000003697_01572;MGYG000002834_00477 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,4NECB@976|Bacteroidetes,2FNV6@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation 1.0 metG 1.0 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.10 1.0 ko:K01874 1.0 ko00450,ko00970,map00450,map00970 1.0 M00359,M00360 1.0 R03659,R04773 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 Anticodon_1,tRNA-synt_1g,tRNA_bind 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01572 0.5 methionine--tRNA ligase. MetRS. In those organisms producing N-formylmethionyl-tRNA(fMet) for translation initiation, this enzyme also recognizes the initiator tRNA(fMet) and catalyzes the formation of L-methionyl-tRNA(fMet), the substrate for EC 2.1.2.9. ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl- tRNA(Met). 1.0 1.0 1.0 1.0 Selenocompound metabolism|Aminoacyl-tRNA biosynthesis 1.0 K01874:MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134563 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 71190 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 491858 0 0 269998 0 0 0 0 0 0 0 0 0 0 0 343428 0 0 0 382223 593378 347374 0 0 0 263994 0 0 0 0 292745 0 0 0 0 268241 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPILLEPIMK MGYG000000050_01748;MGYG000004501_01155;MGYG000000201_03874 domain d__Bacteria 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.6666666666666666 186801|Clostridia 0.6666666666666666 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000000050_01748 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 520371 0 0 0 0 0 0 0 0 0 0 0 146052 0 0 0 539005 94195 225832 0 0 0 0 0 0 0 0 0 0 0 0 0 357500 0 0 141867 0 0 212720 0 0 0 0 0 0 0 0 0 0 0 815317 0 0 0 0 298097 530316 0 0 0 502776 0 0 934718 0 92931 0 0 0 0 410229 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 107063 0 170844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105057 0 0 0 0 0 87251 0 0 0 115452 0 0 0 0 0 0 0 0 0 0 0 0 765000 0 0 895719 0 0 0 0 0 0 0 0 0 0 0 208386 0 0 0 1486973 511218 998424 0 0 0 736553 0 0 484385 0 1368425 0 0 0 0 698283 +AAPILLEPIMR MGYG000000171_02843;MGYG000004733_01212 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000000171_02843 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPILLEPIMR(Arg->Lys) MGYG000000171_02843;MGYG000004733_01212 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000000171_02843 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPIYENGTPEQK MGYG000000084_00625;MGYG000002619_02237;MGYG000001300_00293;MGYG000004732_01390;MGYG000001255_01112;MGYG000002040_01717 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WI1F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000084_00625 0.16666666666666666 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 1444059 763405 2169331 1847161 686322 1713453 1477043 1056434 2117547 1342467 1701261 1537255 1265897 2139833 1297205 1226564 0 1012158 2720493 1968990 0 1405866 986311 1665344 1542051 1865507 1733362 896211 0 1512823 1635071 826079 1515623 2890445 0 1414269 1465233 2135939 1316081 1785205 2265605 1135024 1193882 1648489 1548345 979253 1776496 443282 2082391 2126299 1253833 1363339 1140958 1210786 0 1385174 2043952 1213128 0 964620 1962134 1003013 1753886 1199790 1112888 1373053 0 1398405 1386622 1944925 1953268 1194515 0 1126898 884906 1382869 614345 1031278 1661717 844179 1899234 1201577 1225767 682452 1521792 534336 1887273 1197807 940717 1324846 699676 1302493 0 1912163 788368 736998 0 817688 1486351 1452724 791678 714639 538615 1088582 0 1310847 1652416 703975 860188 805699 0 1176793 807019 1361227 1145883 1543710 2666577 1609161 2434159 1801367 3310167 1081043 2027068 1578160 1495179 2057076 1415448 1514698 1441072 1071099 0 2362518 2254536 1555229 0 1714508 1424869 1841034 2079816 1762509 1495417 2512490 0 1515789 2224794 1671753 1945914 1744139 0 1454250 1059127 2600413 0 0 165270 0 0 0 0 0 0 0 0 0 119779 0 0 0 0 521994 0 255511 0 0 600790 94924 0 0 0 740171 0 0 0 0 377812 0 0 0 125277 386862 +AAPKPIVRPEVSDEEVSK MGYG000000074_02676 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0532@1|root,COG0532@2|Bacteria,4NGP3@976|Bacteroidetes,2FM01@200643|Bacteroidia,22UXN@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000000074_02676 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210621 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 739853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1069684 0 0 0 0 0 0 0 0 +AAPKSEEK MGYG000001637_00284 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp900543445|m__MGYG000001637 1.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001637_00284 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 0 0 213405 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 932311 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507389 0 0 0 0 676660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 475940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 340177 0 0 0 0 532529 +AAPLGTGIYK MGYG000001661_02539;MGYG000001313_02992 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,2FMPE@200643|Bacteroidia,4AMTS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase 1.0 ilvE 1.0 - 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001661_02539 0.5 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Valine, leucine and isoleucine degradation|Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00826:E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 470368 0 0 0 0 472954 0 0 0 0 399280 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2382296 0 0 0 0 1802446 0 0 0 0 1939537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321255 0 0 0 0 0 0 0 0 0 174788 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1348453 0 0 0 0 1144416 0 0 0 0 835624 0 0 0 0 0 0 0 0 0 0 +AAPLGTGTFK MGYG000001306_01027;MGYG000001599_02056;MGYG000003693_03058;MGYG000001364_00192 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,2FMPE@200643|Bacteroidia,4AMTS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase 1.0 ilvE 1.0 - 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001306_01027 0.25 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Valine, leucine and isoleucine degradation|Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00826:E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2485263 0 0 0 0 3412574 0 0 0 0 3025992 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 534482 0 0 0 0 318061 0 0 0 0 402174 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPNALYLIVSNPVDIMTYVFTK MGYG000001338_01861 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A wexlerae_A|m__MGYG000001338 1.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3XZ3D@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 ldh 1.0 - 1.0 1.1.1.27 1.0 ko:K00016 1.0 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 1.0 - 1.0 R00703,R01000,R03104 1.0 RC00031,RC00044 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Ldh_1_C,Ldh_1_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001338_01861 1.0 L-lactate dehydrogenase. L-lactic dehydrogenase. Also oxidizes other (S)-2-hydroxymonocarboxylic acids.-!-NADP(+) acts, more slowly, with the animal, but not the bacterial, enzyme. (S)-lactate + NAD(+) = H(+) + NADH + pyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Cysteine and methionine metabolism|Pyruvate metabolism|Propanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Glucagon signaling pathway 1.0 K00016:LDH, ldh; L-lactate dehydrogenase [EC:1.1.1.27] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2250085 0 482004 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 83956 0 0 0 0 0 0 0 1797745 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3238843 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2515564 0 0 0 0 0 +AAPNGTGHIK MGYG000001652_01374;MGYG000000193_03518 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,27INK@186928|unclassified Lachnospiraceae 0.5 186801|Clostridia 1.0 EH 1.0 Amino-transferase class IV 1.0 ilvE 1.0 - 1.0 2.6.1.42,4.1.3.38 1.0 ko:K00826,ko:K02619 1.0 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R05553,R10991 1.0 RC00006,RC00036,RC01843,RC02148 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001652_01374 0.5 branched-chain-amino-acid transaminase. | aminodeoxychorismate lyase. transaminase B. | enzyme X. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. | Forms part of the folate biosynthesis pathway.-!-Acts on 4-amino-4-deoxychorismate, the product of EC 2.6.1.85, to form p-aminobenzoate. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. | 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Valine, leucine and isoleucine degradation|Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Folate biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00826:E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]|K02619:pabC; 4-amino-4-deoxychorismate lyase [EC:4.1.3.38] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 647239 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18106 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPNLPEIR MGYG000003697_02941 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1435@1|root,COG1435@2|Bacteria,4NFWU@976|Bacteroidetes,2FNY3@200643|Bacteroidia,4APFH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_02941 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 527553 0 898397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610101 0 0 0 0 703025 0 0 0 0 134835 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPNTIPTAAK MGYG000002534_04862;MGYG000002385_03572;MGYG000002515_03619;MGYG000002477_00691;MGYG000002494_01536 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RP6Z@1236|Gammaproteobacteria,3XMH2@561|Escherichia 0.8 1236|Gammaproteobacteria 1.0 E 1.0 Acts on leucine, isoleucine and valine 0.8 ilvE 1.0 GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 iB21_1397.B21_03597,iECBD_1354.ECBD_4269,iECB_1328.ECB_03648,iECD_1391.ECD_03648,iECO103_1326.ECO103_4394 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002534_04862 0.2 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Valine, leucine and isoleucine degradation|Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00826:E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42] 1.0 none 1.0 0 0 397689 0 0 0 0 0 0 253769 0 115101 0 0 0 0 188371 0 0 0 0 0 0 0 344513 0 0 0 0 172581 0 0 336994 0 0 0 0 428237 0 0 3068364 0 0 0 0 0 0 1943073 0 808335 0 0 0 0 3935241 0 0 0 0 0 0 0 2423326 0 0 0 0 3321351 0 0 3107485 0 0 0 0 2285853 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 541820 0 0 0 0 0 0 478450 0 0 0 0 0 0 0 300539 0 0 0 0 218707 0 0 0 0 0 0 0 292496 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPPPPPAPKPEVATK MGYG000002834_01606;MGYG000003697_01975;MGYG000002293_00416 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0226@1|root,COG0226@2|Bacteria,4NH1N@976|Bacteroidetes,2FNG9@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 P 1.0 COG0226 ABC-type phosphate transport system, periplasmic component 1.0 - 1.0 - 1.0 - 1.0 ko:K02040 1.0 ko02010,ko02020,ko05152,map02010,map02020,map05152 1.0 M00222 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.7 1.0 - 1.0 - 1.0 PBP_like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002834_01606 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Two-component system|Tuberculosis 1.0 K02040:pstS; phosphate transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3435002 0 0 2985217 0 0 0 0 2876259 0 0 0 0 0 0 2944886 0 0 0 2867485 1094501 3439962 0 0 0 4162999 0 0 0 1471630 2137841 0 0 0 0 3311304 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPSGASTGSR MGYG000002506_02347;MGYG000000093_02751;MGYG000001692_04471 order d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales 1.0 COG0148@1|root,COG0148@2|Bacteria,1MU1N@1224|Proteobacteria,1RNQA@1236|Gammaproteobacteria,3XNNK@561|Escherichia 0.6666666666666666 1236|Gammaproteobacteria 0.6666666666666666 F 1.0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis 1.0 eno 1.0 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 0.6666666666666666 4.2.1.11 1.0 ko:K01689 1.0 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 1.0 M00001,M00002,M00003,M00346,M00394 1.0 R00658 1.0 RC00349 1.0 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 1.0 - 1.0 - 1.0 iPC815.YPO3376 0.6666666666666666 Enolase_C,Enolase_N 1.0 - 1.0 - 1.0 - 1.0 GH13_31 1.0 MGYG000002506_02347 0.3333333333333333 phosphopyruvate hydratase. enolase. Also acts on 3-phospho-D-erythronate. (2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|RNA degradation|HIF-1 signaling pathway 1.0 K01689:ENO1_2_3, eno; enolase 1/2/3 [EC:4.2.1.11] 1.0 none 1.0 97219 0 201443 0 137431 569052 169602 255767 282365 289536 176841 0 0 0 351527 0 116475 0 396805 0 244395 523659 0 479669 292147 321549 0 0 203492 208881 0 168922 78809 489028 417820 0 174702 360555 179572 112813 159254 0 175850 236603 242955 268688 290635 199609 87151 0 0 0 164835 52663 293514 0 612989 0 163011 91580 0 0 194615 77326 0 0 50595 56136 0 186511 138002 119717 208428 169144 118697 140376 94686 138450 328840 0 134837 443656 126782 124446 228642 230106 65064 0 0 0 295658 261742 68329 0 97373 0 258238 396732 0 555199 337999 0 0 0 103008 38004 0 0 234492 225645 189297 222777 170728 254956 2424666 2712867 2263243 0 1502669 2883081 7377318 1856563 2663013 2574325 1130813 0 0 0 700388 2272225 3005654 0 1718267 0 1257304 5840114 0 3137658 1803981 1653363 0 0 3095267 2009989 0 1324125 1408703 1629587 3218923 1033191 1918087 3681128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPSMSHNVSIQGTSGK MGYG000001346_02330 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM2D@200643|Bacteroidia,4AK7X@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,STN,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_02330 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546651 0 0 0 0 0 0 0 605244 940183 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 602853 638704 0 493999 0 0 596856 0 0 0 0 0 0 0 0 0 0 0 141834 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 445546 0 0 0 0 0 0 0 0 323167 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPSNIK MGYG000002517_00959;MGYG000000076_02414 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1145@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1145@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_6,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002517_00959 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 137252 54718 93059 0 0 0 0 183688 118170 0 0 0 0 82574 123293 0 83490 0 0 69534 70656 0 0 0 41161 80305 0 0 0 0 0 0 57748 0 0 93129 44722 384135 0 119076 0 0 0 0 0 170946 0 0 0 0 0 0 0 0 0 0 0 0 47968 0 0 0 0 0 0 0 0 0 0 0 27550 0 0 0 0 0 374719 185850 74312 0 0 0 0 160111 74439 0 0 0 0 150011 201214 0 452652 0 0 161686 317402 0 0 0 272286 527809 0 0 0 0 0 0 161188 0 0 175130 141219 0 132206 0 0 0 0 0 0 346665 693576 0 0 0 0 599781 456865 0 42552 0 0 358788 869559 0 0 0 458206 251352 0 0 0 0 0 0 56117 0 0 614307 347883 103171 1116660 2269492 423268 0 0 0 0 1315076 453256 0 0 0 0 955957 911343 0 1857927 0 0 1688649 3204883 0 0 0 273689 576526 0 0 0 0 0 0 883979 0 0 809979 938551 255494 +AAPSTVK MGYG000002291_02265 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__OM05-12|s__OM05-12 sp003438995|m__MGYG000002291 1.0 COG0222@1|root,COG0222@2|Bacteria,4NQAQ@976|Bacteroidetes,2FSJH@200643|Bacteroidia,4AQYQ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation 1.0 rplL 1.0 - 1.0 - 1.0 ko:K02935 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L12,Ribosomal_L12_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002291_02265 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02935:RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12 1.0 none 1.0 0 0 0 0 0 68210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1159350 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 578910 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 552028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPSYEELSNSQELLETGIK MGYG000002323_04215;MGYG000000093_05344;MGYG000002515_03903;MGYG000002506_03402;MGYG000002494_02404;MGYG000002366_00010;MGYG000002507_04224 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0055@1|root,COG0055@2|Bacteria,1MUFU@1224|Proteobacteria,1RN6U@1236|Gammaproteobacteria,3XPEM@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 F 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits 1.0 atpD 1.0 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 1.0 3.6.3.14 1.0 ko:K02112 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 e_coli_core.b3732,iAF1260.b3732,iAPECO1_1312.APECO1_2729,iB21_1397.B21_03560,iBWG_1329.BWG_3423,iE2348C_1286.E2348C_4042,iEC042_1314.EC042_4119,iEC55989_1330.EC55989_4207,iECABU_c1320.ECABU_c42160,iECBD_1354.ECBD_4300,iECB_1328.ECB_03616,iECDH10B_1368.ECDH10B_3919,iECDH1ME8569_1439.ECDH1ME8569_3620,iECD_1391.ECD_03616,iECED1_1282.ECED1_4422,iECH74115_1262.ECH74115_5168,iECIAI1_1343.ECIAI1_3916,iECIAI39_1322.ECIAI39_4336,iECNA114_1301.ECNA114_3881,iECO103_1326.ECO103_4426,iECO111_1330.ECO111_4566,iECO26_1355.ECO26_4846,iECOK1_1307.ECOK1_4181,iECP_1309.ECP_3931,iECS88_1305.ECS88_4154,iECSE_1348.ECSE_4022,iECSF_1327.ECSF_3580,iECSP_1301.ECSP_4782,iECUMN_1333.ECUMN_4262,iECW_1372.ECW_m4035,iECs_1301.ECs4674,iEKO11_1354.EKO11_4613,iETEC_1333.ETEC_4023,iEcDH1_1363.EcDH1_4235,iEcE24377_1341.EcE24377A_4247,iEcSMS35_1347.EcSMS35_4100,iEcolC_1368.EcolC_4262,iG2583_1286.G2583_4528,iJO1366.b3732,iJR904.b3732,iLF82_1304.LF82_0194,iNRG857_1313.NRG857_18585,iPC815.YPO4121,iSFV_1184.SFV_3758,iSF_1195.SF3812,iSFxv_1172.SFxv_4154,iSSON_1240.SSON_3887,iS_1188.S3956,iSbBS512_1146.SbBS512_E4189,iUMN146_1321.UM146_18850,iUMNK88_1353.UMNK88_4544,iUTI89_1310.UTI89_C4285,iWFL_1372.ECW_m4035,iY75_1357.Y75_RS18410,iZ_1308.Z5230,ic_1306.c4658 1.0 ATP-synt_ab,ATP-synt_ab_N 1.0 - 1.0 - 1.0 - 1.0 GT58 1.0 MGYG000002323_04215 0.14285714285714285 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02112:ATPF1B, atpD; F-type H+/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 821486 752905 885288 927220 510061 1452718 1121096 848870 910840 1155326 356153 809311 0 971427 696870 300394 985521 0 746987 703158 619743 982846 0 1008678 846754 786381 879606 0 1232995 962536 701750 974048 609870 838286 784518 836816 695207 726993 2215786 3754486 4102252 2602745 3615153 6321430 3304497 2502519 2539304 4506558 1233497 2682556 2633140 0 2656674 2959522 5219642 0 4026673 2194101 4079202 8081576 0 6214515 4543983 3019840 2656033 0 5527443 5093620 2164389 3284546 3884824 2123288 2116860 2366443 2172130 2413783 1101003 1139562 1230954 1234446 1246379 2543860 1473807 1202572 1579615 1239585 799376 1006946 830513 1020602 965095 861437 613689 0 920776 1215918 947521 1869302 0 1817767 1240487 1180337 1199304 0 1160850 1132959 888458 1043753 1176305 1384778 1300140 1350369 1080100 1181753 1747729 1022751 1320755 1035931 1104123 2224023 1980587 1663837 1328631 2018351 816985 834381 1094937 1179704 1120464 1152133 1565785 0 1237418 1403890 1694156 2950553 0 1911865 2177224 1530064 1719942 0 1660102 1385025 710130 1000692 1238177 2054024 1685465 1716941 1112833 1234400 0 189105 141570 0 0 0 0 0 0 0 152046 0 194488 230225 0 0 0 0 0 0 0 0 0 88831 0 93136 0 0 0 0 0 0 0 0 0 0 234101 235032 +AAPVDMTLVDAK MGYG000002720_00480 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83|s__CAG-83 sp000435555|m__MGYG000002720 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,36EA6@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 - 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_10,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002720_00480 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1153556 0 0 0 0 0 0 0 1905528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 625784 0 0 0 0 0 0 0 479302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPVILEPIMK MGYG000000154_02190;MGYG000001338_03374 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia 0.5 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 1.0 MGYG000000154_02190 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1370652 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPVKWDHNVVYNSK MGYG000004271_00865 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900542495|m__MGYG000004271 1.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate 1.0 argJ 1.0 - 1.0 2.3.1.1,2.3.1.35 1.0 ko:K00620 1.0 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 1.0 M00028 1.0 R00259,R02282 1.0 RC00004,RC00064 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ArgJ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004271_00865 1.0 amino-acid N-acetyltransferase. | glutamate N-acetyltransferase. N-acetylglutamate synthase. | ornithine transacetylase. Also acts with L-aspartate and, more slowly, with some other amino acids. | Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity. acetyl-CoA + L-glutamate = CoA + H(+) + N-acetyl-L-glutamate. | L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L- glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00620:argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPVLLEPIM(Oxidation)K MGYG000001637_00070;MGYG000000154_02190;MGYG000004414_01432;MGYG000000417_00151;MGYG000001338_03374;MGYG000000263_00835;MGYG000000142_00172;MGYG000002312_02892;MGYG000000200_01983;MGYG000000216_02407;MGYG000002492_00343;MGYG000001186_01601;MGYG000001607_01044;MGYG000000206_00900 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 0.9285714285714286 MGYG000001637_00070 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 619139 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 253295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPVLLEPIMK MGYG000001637_00070;MGYG000000154_02190;MGYG000004414_01432;MGYG000000417_00151;MGYG000001338_03374;MGYG000000263_00835;MGYG000000142_00172;MGYG000002312_02892;MGYG000000200_01983;MGYG000000216_02407;MGYG000002492_00343;MGYG000001186_01601;MGYG000001607_01044;MGYG000000206_00900 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae 0.5 186801|Clostridia 1.0 J 1.0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome 1.0 fusA 1.0 - 1.0 - 1.0 ko:K02355 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 1.0 - 1.0 - 1.0 - 1.0 GH38 0.9285714285714286 MGYG000001637_00070 0.07142857142857142 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02355:fusA, GFM, EFG; elongation factor G 1.0 none 1.0 868775 2221432 987322 678704 1478942 722070 413933 924740 675703 983545 2309665 1007500 1210412 582581 896643 919985 972645 2588249 796546 907401 966209 753552 2498758 269713 1039789 485822 730115 2954500 965949 638255 767848 1528879 747150 742114 698347 699938 566859 875897 1375360 6201744 1419703 1666482 2487657 884865 1661442 1746585 799309 1001107 1856931 836858 2190830 1035213 960546 1449303 762601 9667013 963214 1691331 1018397 519393 4682865 1531382 1001335 1396890 1521234 7977124 1209807 999638 6264058 2303579 1534265 1485082 1272885 1850880 1109041 1753386 2094178 2588044 3771225 1275669 992630 905595 1539247 1533664 1197119 1439369 1937863 2114235 2163776 1589652 1982033 3318847 1517480 1759546 1418270 1437975 1379473 2002747 3322137 839990 1776978 1557935 1994937 3878553 1154461 1962149 1345703 3167281 5581288 2014510 2129728 1025019 1863901 4656750 561099 3641336 1448931 591854 1848823 839445 705816 453126 559746 657319 1444534 635365 1207293 572137 351366 1145722 768589 2144461 297230 549156 414970 994901 1450502 0 401083 297941 520043 2663895 1005822 582792 3692504 2189588 1406268 0 512888 396152 415978 1799912 326247 3976989 1231897 149155 241723 97645 366098 569248 294985 236948 609817 432620 172132 507286 336904 1202500 168528 777463 214391 293305 230392 389707 1616773 162841 302724 257278 297860 2171986 320645 197353 1971419 2308239 1841003 320499 292402 293172 102978 873918 +AAPVSHIWYFK MGYG000001514_00034;MGYG000002528_01102;MGYG000001642_00113;MGYG000000142_00116;MGYG000003266_00420;MGYG000000501_01311;MGYG000003825_00451;MGYG000002445_01330;MGYG000000146_01134;MGYG000000231_01252;MGYG000000022_02279;MGYG000000245_03244;MGYG000000333_00801;MGYG000000258_01856;MGYG000000989_00162;MGYG000004869_02970;MGYG000001470_03728;MGYG000000164_01117;MGYG000004717_01316;MGYG000000198_01126;MGYG000000271_03640;MGYG000001707_01472;MGYG000000193_02078;MGYG000002517_00198;MGYG000002105_00006;MGYG000000217_01476;MGYG000000262_00026;MGYG000002992_02046;MGYG000002961_00370;MGYG000001714_01233;MGYG000001683_01329;MGYG000003239_00840;MGYG000001338_03383;MGYG000003116_00422;MGYG000000233_00816;MGYG000002074_00230;MGYG000000036_00944;MGYG000000291_00760;MGYG000000002_03603;MGYG000000127_00619;MGYG000000118_01190;MGYG000000417_00095;MGYG000003782.1_00607;MGYG000001424_01001;MGYG000001315_01195;MGYG000004285_00601;MGYG000001300_00284;MGYG000001756_02184;MGYG000002315_00750;MGYG000004681_00046;MGYG000002279_01918;MGYG000000188_00926;MGYG000000249_00041;MGYG000004884_01728;MGYG000002968_00677;MGYG000004630_01089;MGYG000001627_01519;MGYG000000255_01999;MGYG000003391_00537;MGYG000001493_02697;MGYG000003684_05128;MGYG000002775_00054;MGYG000002298_02601;MGYG000000312_01432;MGYG000000084_01993;MGYG000000251_01868;MGYG000001255_01103;MGYG000000371_01545;MGYG000000133_02999;MGYG000001615_01701;MGYG000004221_01655;MGYG000000179_00949;MGYG000002286_02465;MGYG000002106_00979;MGYG000004769_00421;MGYG000003122_00562;MGYG000002492_00340;MGYG000000184_00998;MGYG000000429_01277;MGYG000000802_00744;MGYG000001319_01768;MGYG000002052_00236;MGYG000000404_00524;MGYG000002919_00394;MGYG000001617_00231 domain d__Bacteria 1.0 COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CUED@84998|Coriobacteriia 0.16470588235294117 186801|Clostridia 0.7764705882352941 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 0.9647058823529412 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 0.8352941176470589 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000001514_00034 0.011764705882352941 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 1125679 1234971 791054 556134 1158592 880872 0 1555226 0 0 1289905 0 0 0 926746 0 649936 1754657 1008868 0 1209411 1068612 248242 255309 1239636 0 975985 0 617852 1122766 931616 1020061 819496 0 1000305 1058565 921859 798366 119252 116277 59651 102101 145133 0 0 253132 0 0 52598 0 104143 0 138601 0 0 1238987 160407 276095 318550 371136 975485 150463 219085 168626 162796 1016572 215364 116978 226478 0 0 0 155724 249228 76530 0 338070 158687 301428 266460 109580 215669 0 339560 0 0 157979 0 231709 0 432474 286877 0 214951 467007 474440 256919 271855 264256 208914 233389 260371 455518 230492 350965 339847 0 289685 433021 0 418561 72160 137380 334041 733361 585538 450986 488171 649669 422663 0 535474 0 0 416737 0 632929 0 473381 856344 420050 204961 424497 702354 621448 677843 0 252623 469861 350260 651550 454561 568639 586729 637035 531806 586414 0 580811 420532 532778 232420 100017 67921 74798 184771 73834 292697 0 71859 0 0 0 0 0 0 0 102644 96400 155880 105285 0 81592 102040 274092 0 0 66894 0 175930 0 0 69074 52890 72115 0 0 164007 275261 82440 +AAPVTHIWFFK MGYG000001292_02175 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,4CZ1D@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_A_CTD,RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000001292_02175 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 499630 0 0 0 0 132443 0 0 0 0 356996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPVVPN(Deamidated)GPAK MGYG000003697_01611 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,2FSK4@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 Preprotein translocase SecG subunit 1.0 secG 1.0 - 1.0 - 1.0 ko:K03075 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2 1.0 - 1.0 - 1.0 SecG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01611 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03075:secG; preprotein translocase subunit SecG 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 920908 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPVVPTSPAK MGYG000002293_00368 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG1314@1|root,COG1314@2|Bacteria,4NUYQ@976|Bacteroidetes,2FSK4@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 Preprotein translocase SecG subunit 1.0 secG 1.0 - 1.0 - 1.0 ko:K03075 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.2 1.0 - 1.0 - 1.0 SecG 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00368 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03075:secG; preprotein translocase subunit SecG 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1322197 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1168029 0 0 0 0 1249397 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAPYGTGR MGYG000002171_02681;MGYG000000243_02172;MGYG000002478_00294 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG0115@1|root,COG0115@2|Bacteria,4NEJY@976|Bacteroidetes,2FMPE@200643|Bacteroidia,4AMTS@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase 1.0 ilvE 1.0 - 1.0 2.6.1.42 1.0 ko:K00826 1.0 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00036,M00119,M00570 1.0 R01090,R01214,R02199,R10991 1.0 RC00006,RC00036 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002171_02681 0.3333333333333333 branched-chain-amino-acid transaminase. transaminase B. Also acts on L-isoleucine and L-valine.-!-Different from EC 2.6.1.66. 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate. 1.0 1.0 1.0 1.0 Cysteine and methionine metabolism|Valine, leucine and isoleucine degradation|Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00826:E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42] 1.0 none 1.0 0 0 4516852 0 3069845 2015573 7090623 0 0 1729708 0 2194669 3768523 5642408 7440498 3149501 2075648 2610108 2185751 0 0 1894223 2676027 6225557 6850753 0 0 3029407 0 7525515 0 0 4457881 8322683 0 0 0 4171330 0 0 1253316 0 1880919 2008390 1918775 0 0 3481002 0 2148664 3038645 1743719 2308863 3290692 1528166 928635 2483197 0 0 1585386 2231945 1451956 1951071 0 0 2081390 0 1989398 0 0 1704128 2312460 0 0 0 1557148 0 0 1911284 0 1463429 1353991 1702666 0 0 1423193 0 2405351 1618447 1471546 1000183 1532556 1697737 1231042 1203289 0 0 1586061 1741864 2046496 1101064 0 0 2484287 0 1176707 0 0 1295600 1001256 0 0 0 1370912 0 0 242375 0 429103 454537 249814 0 0 404978 0 1044966 328116 274668 249045 448426 0 603090 446657 0 0 446537 0 859150 460409 0 0 887324 0 0 0 0 319155 1260267 0 0 0 657735 0 0 981745 0 1787114 1713228 1272261 0 0 516904 0 1101450 2080565 823041 1242986 1574720 745719 2354711 844788 0 0 1199378 2274016 967411 0 0 0 1417854 0 696211 0 0 783388 997057 0 0 0 1002940 +AAQAAAEAAAPEAE MGYG000001292_02324 genome d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium|s__Bifidobacterium infantis|m__MGYG000001292 1.0 COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,4CYTW@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 K 1.0 Participates in both transcription termination and antitermination 1.0 nusA 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 1.0 - 1.0 ko:K02600 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03009,ko03021 1.0 - 1.0 - 1.0 - 1.0 DUF448,KH_5,NusA_N,S1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001292_02324 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02600:nusA; transcription termination/antitermination protein NusA 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604317 0 0 0 0 95926 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQAAAGAAAGEK MGYG000002517_00513 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1645@1|root,COG1645@2|Bacteria,1TRYG@1239|Firmicutes,25F3V@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 bacterial-type flagellum-dependent swarming motility 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00513 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 600367 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 522837 659709 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 254863 265233 0 0 0 0 0 0 0 0 0 0 0 +AAQAAAGGPGLQVK MGYG000001302.1_01546 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes putredinis|m__MGYG000001302.1 1.0 COG4770@1|root,COG4770@2|Bacteria,4NSWV@976|Bacteroidetes,2FRYI@200643|Bacteroidia,22UGJ@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 I 1.0 Biotin-requiring enzyme 1.0 mmdC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Biotin_lipoyl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001302.1_01546 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134458 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401011 0 0 0 0 481225 0 0 0 0 377439 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 913396 0 0 0 0 651176 0 0 0 0 677082 0 0 0 0 0 0 0 0 0 0 +AAQAAIAEK MGYG000000133_02955;MGYG000002298_01806;MGYG000000184_00575;MGYG000001687_00537;MGYG000004733_01907;MGYG000000171_00241;MGYG000000153_02081;MGYG000004785_01840;MGYG000000262_01988;MGYG000001637_01169;MGYG000003366_01811;MGYG000003694_01656 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia 0.3333333333333333 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.5833333333333334 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000133_02955 0.08333333333333333 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 431788 1263631 0 1939892 999547 0 0 0 0 1384803 0 0 170776 0 768335 302041 0 0 939973 0 1225112 0 464828 0 0 0 0 1023353 0 393201 891447 0 0 0 0 0 607088 0 221427 353281 0 414629 0 0 0 0 0 0 0 0 0 0 259650 165167 0 0 303285 0 387938 0 198703 0 0 0 0 375395 0 131086 149892 116414 0 0 0 0 174988 0 1061789 277486 0 241809 273706 0 0 0 0 258443 0 0 554931 0 325262 838084 0 0 661671 0 609313 0 198924 0 0 0 0 408538 0 213721 732883 778405 0 0 0 0 326205 0 6450057 2622319 0 3712527 1939140 0 0 0 0 2222398 0 0 1487938 0 3629355 2165121 0 0 2282936 0 2917292 0 6245899 0 0 0 0 6642659 0 13026683 2461823 2879180 0 0 0 0 7038591 0 350159 0 0 105206 82332 0 0 0 0 519258 0 0 0 0 147886 0 0 0 0 0 0 0 0 0 0 0 0 327195 0 287844 467701 0 0 0 0 0 149618 +AAQAAIANK MGYG000000231_00504;MGYG000001319_00729;MGYG000000280_02154;MGYG000000154_00436;MGYG000001374_00487;MGYG000002517_01243;MGYG000000245_03386;MGYG000000258_01879;MGYG000001698_00702;MGYG000004891_00190;MGYG000000076_02377 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 0.7272727272727273 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000231_00504 0.09090909090909091 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 489516 0 385267 731100 332873 291162 517251 614249 953885 720556 0 243094 0 565209 1312937 290870 0 3334053 923530 225792 728924 675049 2360573 0 1217231 632874 760421 3211089 309860 457636 0 469920 215027 929468 519806 0 657889 237548 0 0 0 100301 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 544219 300595 294991 615967 0 240104 306567 952198 742089 712598 333248 412212 0 726249 1503551 416985 598170 0 1026388 1415569 1146003 0 72599 142459 909279 753374 953613 0 638572 421876 243754 0 224220 685030 994922 0 1171707 353852 6627809 3074590 1535342 9781989 3691510 2782062 4770740 5384114 9460165 3253508 2584203 3033519 0 8536661 2688221 4823675 7335930 2397084 6464423 10750128 1120760 1864436 206711 2205948 3530006 4781773 8244693 4998427 2981489 5801966 2809520 1838655 1098241 2203689 4629574 0 6821605 2925054 0 150498 0 0 1271147 719734 259769 0 2301525 600739 386186 0 0 726274 0 0 140522 271114 0 1760066 258443 1242785 341720 495915 0 0 0 0 1772952 0 0 128285 514767 0 1737496 0 272524 0 +AAQAAIKNPR MGYG000001647_00185;MGYG000004866_01031;MGYG000000022_02788;MGYG000001597_00394;MGYG000000312_02404;MGYG000000278_00304;MGYG000001157_01952;MGYG000003899_02226;MGYG000003921_00033;MGYG000003166_00833;MGYG000003819_01577;MGYG000002707_01357;MGYG000002545_01217;MGYG000000636_01370;MGYG000002274_02693;MGYG000002105_00879;MGYG000002224_02000;MGYG000001300_02837;MGYG000002953_01784;MGYG000001255_00900;MGYG000002040_00906;MGYG000004732_02304;MGYG000000087_02439 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.7391304347826086 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 0.9565217391304348 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000001647_00185 0.043478260869565216 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 636700 441479 1043114 662313 766123 583986 537152 0 783994 799969 916963 674556 892456 921036 1140627 686911 0 1568674 1589254 846771 656872 830806 1259044 715816 987552 1030511 668069 1685119 599619 597497 716556 583072 993421 1081610 822547 0 706115 752209 230738 90968 194216 85876 185442 224407 266374 0 207315 149487 208306 207969 187239 273547 153880 174793 0 119593 334317 337987 73616 196172 206198 76587 250032 194350 185886 163749 174635 167659 80162 273577 156231 190107 138293 0 187521 145101 142202 222524 169255 307313 123779 242667 240761 0 177586 221818 212066 193201 194416 231003 204339 156270 0 284053 213208 155934 259202 146800 259574 206583 155985 261292 142290 394492 212354 208535 180594 81957 112796 204352 239414 0 248419 148863 535856 863542 1061895 788806 1016263 1057078 891941 0 843269 728392 715646 972787 780376 783269 637588 1003685 0 1217040 1097107 791269 314025 1235103 202884 2250046 398834 379076 659738 1454029 668621 871686 2151912 774391 1132291 582182 469673 0 572221 2153117 0 111288 43725 69043 103790 0 0 0 0 144569 0 0 193090 0 60302 94895 0 191923 100945 57655 64847 0 160992 180400 192124 183290 108803 89313 126712 167275 129545 127261 178966 0 145192 0 0 133277 +AAQAAINQK MGYG000000164_00358;MGYG000002279_01986;MGYG000004296_00104 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000164_00358 0.3333333333333333 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235132 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 364453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQAAISNK MGYG000000271_00388 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000000271_00388 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 580531 0 0 0 0 0 408270 0 672442 0 0 0 0 0 0 0 0 859431 798040 0 602074 0 582648 0 0 517133 0 845454 0 0 0 0 0 940131 0 446000 427564 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 294190 0 220576 0 0 0 0 144991 0 0 0 0 0 0 0 0 0 159168 71104 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 149934 0 0 0 0 461017 0 0 0 0 0 0 0 0 0 0 381361 0 0 0 0 0 849983 0 526358 0 0 0 0 0 0 0 0 1224542 0 0 397075 0 329555 0 0 283437 0 952621 0 0 0 0 0 359056 0 192234 449268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQAALDEGLKELGK MGYG000000045_02091 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG4166@1|root,COG4166@2|Bacteria,2NPWR@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000045_02091 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 407036 0 0 0 0 370006 0 0 0 0 403272 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2360134 0 0 0 0 1290348 0 0 0 0 1977437 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 304928 0 0 0 0 556341 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 70315 0 0 0 0 0 0 0 0 0 0 +AAQAALDEGLKELGKSEITIR MGYG000000045_02091 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelatoclostridiaceae|g__Faecalibacillus|s__Faecalibacillus intestinalis|m__MGYG000000045 1.0 COG4166@1|root,COG4166@2|Bacteria,2NPWR@2323|unclassified Bacteria 1.0 2|Bacteria 1.0 E 1.0 Bacterial extracellular solute-binding proteins, family 5 Middle 1.0 oppA 1.0 - 1.0 - 1.0 ko:K02035,ko:K15580 1.0 ko01501,ko02010,ko02024,map01501,map02010,map02024 1.0 M00239,M00439 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 1.0 - 1.0 - 1.0 Cu_amine_oxidN1,SBP_bac_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000045_02091 1.0 - - - - 1.0 1.0 1.0 1.0 beta-Lactam resistance|ABC transporters|Quorum sensing 1.0 K02035:ABC.PE.S; peptide/nickel transport system substrate-binding protein|K15580:oppA, mppA; oligopeptide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQAAVAPNTTEGGDK MGYG000002492_01486 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter rectalis|m__MGYG000002492 1.0 COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfE 1.0 - 1.0 - 1.0 ko:K03613 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS05585 1.0 FMN_bind,Rnf-Nqr 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002492_01486 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03613:rnfE; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit E 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 860976 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQAAVEDMK MGYG000002478_03849 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola dorei|m__MGYG000002478 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,4NEHE@976|Bacteroidetes,2FM8K@200643|Bacteroidia,4AK5V@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the PEP-utilizing enzyme family 1.0 ppdK 1.0 - 1.0 2.7.9.1 1.0 ko:K01006 1.0 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 1.0 M00169,M00171,M00172,M00173 1.0 R00206 1.0 RC00002,RC00015 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 1.0 - 1.0 - 1.0 - 1.0 GT1 1.0 MGYG000002478_03849 1.0 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 1.0 1.0 1.0 1.0 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 852859 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 315453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQAGDWATVK MGYG000004681_01408 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__|m__MGYG000004681 1.0 COG0329@1|root,COG0329@2|Bacteria,2GJDB@201174|Actinobacteria,4CUG0@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 EM 1.0 Belongs to the DapA family 1.0 - 1.0 - 1.0 4.3.3.7 1.0 ko:K01714 1.0 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 1.0 M00016,M00525,M00526,M00527 1.0 R10147 1.0 RC03062,RC03063 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHDPS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004681_01408 1.0 4-hydroxy-tetrahydrodipicolinate synthase. dihydrodipicolinate synthetase. The reaction can be divided into three consecutive steps: Schiff base formation with pyruvate, the addition of L-aspartate-semialdehyde, and finally transimination leading to cyclization with simultaneous dissociation of the product.-!-The product of the enzyme was initially thought to be (S)-2,3- dihydrodipicolinate, and the enzyme was classified accordingly as EC 4.2.1.52.-!-Later studies of the enzyme from the bacterium Escherichia coli have suggested that the actual product of the enzyme is (2S,4S)-4-hydroxy- 2,3,4,5-tetrahydrodipicolinate, and thus the enzyme has been reclassified as 4-hydroxy-tetrahydrodipicolinate synthase.-!-However, the identity of the product is still controversial, as more recently it has been suggested that it may be (S)-2,3- dihydrodipicolinate after all.-!-Formerly EC 4.2.1.52. L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5- tetrahydrodipicolinate + H(+) + H2O. 1.0 1.0 1.0 1.0 Monobactam biosynthesis|Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01714:dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1199672 0 0 0 0 1041285 0 0 0 0 1290547 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1567264 0 0 0 0 746430 0 0 0 0 1348477 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 179032 0 0 0 0 445488 0 0 0 0 785999 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 885696 0 0 0 0 1090679 0 0 0 0 1949158 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210843 0 0 0 0 449461 0 0 0 0 279553 0 0 0 0 0 0 0 0 0 0 +AAQAIDAFDYR MGYG000000243_03324 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1629@1|root,COG1629@2|Bacteria,4NDXS@976|Bacteroidetes,2FM37@200643|Bacteroidia,4AKK0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB-linked outer membrane protein, SusC RagA family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_03324 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 5579398 5935580 17984410 6485355 6516747 4871087 7449644 6905584 6650214 4038527 3456570 3983652 5961607 5217164 5463361 6476279 6203688 2735028 4803027 4618842 5302920 4058916 4236158 6505759 5311724 4887281 5752213 3661205 6444841 4771737 11498542 6627666 19688785 6292788 5466058 6336246 5819165 16338919 2501279 0 442117 449118 2046586 0 0 0 2348549 6864907 358288 0 0 469160 493090 0 0 0 2274657 1648556 0 0 0 0 424529 0 0 0 1818002 2728087 737756 0 771251 746479 754039 529720 1907703 576780 254245 559081 455120 0 242753 0 706431 392173 869062 612469 640766 334403 281092 337321 892163 249586 956733 0 485558 501840 317675 776959 781542 400703 236081 455696 245872 445131 1079703 728571 788540 299569 504076 804898 519910 363098 0 860590 432317 336743 477477 561443 702618 333895 568622 650055 259180 538841 157882 142996 1092943 591416 415614 202594 177925 902039 922892 586749 0 324524 1245690 861623 660669 468856 307592 1458561 171570 522359 1322185 640060 710005 757185 663145 328353 471056 464476 0 373041 1048587 612893 332501 697784 377137 937593 310923 170952 254550 626467 0 0 977599 369572 869334 0 631136 384113 579134 0 0 243701 759202 0 475201 953695 1138918 0 755950 337769 820334 0 0 0 752344 565423 +AAQAQLPC(Carbamidomethyl)PEVTESAAPAK MGYG000002556_00167 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-279|s__CAG-279 sp000437795|m__MGYG000002556 1.0 COG2885@1|root,COG2885@2|Bacteria,4NKQC@976|Bacteroidetes,2FRBK@200643|Bacteroidia,22X13@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 M 1.0 membrane 1.0 - 1.0 GO:0001871,GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0006810,GO:0008150,GO:0015267,GO:0015288,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030246,GO:0030247,GO:0051179,GO:0051234,GO:0055085 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002556_00167 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1869776 0 0 0 0 1515336 0 0 0 0 770351 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQAVATM(Oxidation)R MGYG000002834_01329;MGYG000002549_01140;MGYG000002960_01369;MGYG000004876_01717;MGYG000004561_01315;MGYG000001783_00644;MGYG000000236_00811;MGYG000002455_04080;MGYG000000196_03727;MGYG000001337_00793;MGYG000003697_00353 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 0.6363636363636364 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002834_01329 0.09090909090909091 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01818:fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQAVATMR MGYG000002834_01329;MGYG000002549_01140;MGYG000002960_01369;MGYG000004876_01717;MGYG000004561_01315;MGYG000001783_00644;MGYG000000236_00811;MGYG000002455_04080;MGYG000000196_03727;MGYG000001337_00793;MGYG000003697_00353 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG2407@1|root,COG2407@2|Bacteria,4NHWI@976|Bacteroidetes,2FNPS@200643|Bacteroidia,4AK5W@815|Bacteroidaceae 0.6363636363636364 976|Bacteroidetes 1.0 G 1.0 Converts the aldose L-fucose into the corresponding ketose L-fuculose 1.0 fucI 1.0 - 1.0 5.3.1.25,5.3.1.3 1.0 ko:K01818 1.0 ko00051,ko01120,map00051,map01120 1.0 - 1.0 R03163 1.0 RC00434 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002834_01329 0.09090909090909091 L-fucose isomerase. | D-arabinose isomerase. L-fucose isomerase. The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme from Escherichia coli can also convert D-arabinose to D-ribulose.-!-The enzyme from the thermophilic bacterium Caldicellulosiruptor saccharolyticus also converts D-altrose to D-psicose and L-galactose to L-tagatose. | The enzyme binds the closed form of the sugar and catalyzes ring opening to generate a form of open-chain conformation that facilitates the isomerization reaction, which proceeds via an ene- diol mechanism.-!-The enzyme catalyzes the aldose-ketose isomerization of several sugars.-!-Most enzymes also catalyze the reaction of EC 5.3.1.25.-!-The enzyme from the bacterium Falsibacillus pallidus also converts D-altrose to D-psicose. cf. EC 5.3.1.4. L-fucose = L-fuculose. | D-arabinose = D-ribulose. 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01818:fucI; L-fucose/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3] 1.0 none 1.0 2601739 0 0 2828075 1815854 2608457 2690686 2145872 2710639 2438144 1332173 2197791 1871842 3170151 3224222 1498983 1773883 412957 2737599 3669321 2961409 2366548 768107 2053648 3077157 2575818 2238524 470274 2729060 2326988 1745006 2112682 1758869 2491608 0 2327487 2452914 1867831 2201785 0 1499862 2097610 0 0 0 0 1540472 2152970 1348145 1619852 1178961 1786743 2202225 1297299 1577273 0 1839511 1771980 2187372 0 1038328 1041814 1867881 2362873 1732045 741032 0 1687104 797462 1085145 1645091 1859507 0 0 1932041 1693415 0 0 2565329 1730030 1747856 1668600 2135352 0 2673930 0 1398941 1595606 1785050 2013188 2399274 1729096 0 1012187 1795129 2772187 2745647 0 1049970 1677419 0 2282112 2779353 685568 2656652 2023539 1398990 0 1089360 2449228 0 2498092 2374823 1744128 2591922 0 3065762 2002679 4356504 2937156 2303340 2568703 2600143 2487450 2115229 2492800 3063165 1633107 2694789 3698288 2762964 4797657 1800024 2376724 1668326 4137331 2411138 2854416 2109742 2520904 2506892 3719410 4402046 1851353 3205141 3948511 2196369 2792648 0 2362966 2283898 2723227 5737344 0 3711352 5738984 3764486 3613299 4531792 4016166 4071289 4457242 2888450 3939939 5943911 3562191 4588503 4395966 3955899 1607119 4556646 3963439 4563055 4149610 1259764 4130611 4459077 5762021 4626216 829618 1906211 4857226 3165149 4573938 4023352 5338995 0 6381223 4400150 0 +AAQAVIGETLVR MGYG000000249_00979;MGYG000002772_02240 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter 1.0 COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TPR4@1239|Firmicutes,248TM@186801|Clostridia,36EWP@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 selenate reductase YgfK 1.0 - 1.0 - 1.0 1.97.1.9 1.0 ko:K12527 1.0 ko00450,map00450 1.0 - 1.0 R07229 1.0 RC02420 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Fer4_20,Pyr_redox_2,Pyr_redox_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_00979 0.5 selenate reductase. - The periplasmic enzyme from Thauera selenatis is a complex comprising three heterologous subunits (alpha, beta and gamma).-!-Nitrate, nitrite, chlorate and sulfate are not substrates.-!-A number of compounds, including acetate, lactate, pyruvate, and certain sugars, amino acids, fatty acids, di- and tricarboxylic acids, and benzoate can serve as electron donors. A + H2O + selenite = AH2 + selenate. 1.0 1.0 1.0 1.0 Selenocompound metabolism 1.0 K12527:ygfK; putative selenate reductase [EC:1.97.1.9] 1.0 none 1.0 585805 0 0 423901 0 790879 187838 0 0 0 0 0 0 0 0 0 0 0 0 481321 0 754190 0 1229372 355819 471707 0 0 423081 0 0 0 0 867501 957848 518004 567226 0 2916750 0 0 2391800 0 1441614 2770677 0 0 0 0 0 0 0 0 0 0 0 0 2754127 0 0 0 3570364 2416273 2170111 0 0 2545301 0 0 0 0 3420311 3134984 3216574 2508607 0 400583 0 0 585428 0 240139 295629 0 0 0 0 0 0 0 0 0 0 0 0 244015 0 124143 0 416739 348844 182838 0 0 55809 0 0 0 0 490692 254471 297047 236422 0 863391 0 0 649787 0 1163702 1007722 0 0 0 0 0 0 0 0 0 0 0 0 707824 0 1332962 0 1020590 262236 972704 0 0 544287 0 0 0 0 161221 672077 639678 781161 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQDALENGTGK MGYG000001313_03153 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,4AKGG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_03153 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 428011 0 0 0 0 0 0 0 0 0 0 1492350 0 0 0 0 1042868 0 0 0 0 961783 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQDDADVQSAVR MGYG000002279_01925 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Dorea_A|s__Dorea_A longicatena_B|m__MGYG000002279 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,27V02@189330|Dorea 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate 1.0 glmM 1.0 - 1.0 5.4.2.10 1.0 ko:K03431 1.0 ko00520,ko01100,ko01130,map00520,map01100,map01130 1.0 - 1.0 R02060 1.0 RC00408 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002279_01925 1.0 phosphoglucosamine mutase. - The enzyme is involved in the pathway for bacterial cell-wall peptidoglycan and lipopolysaccharide biosyntheses, being an essential step in the pathway for UDP-N-acetylglucosamine biosynthesis.-!-The enzyme from Escherichia coli is activated by phosphorylation and can be autophosphorylated in vitro by alpha-D-glucosamine 1,6- bisphosphate, which is an intermediate in the reaction, alpha-D- glucose 1,6-bisphosphate or ATP.-!-It can also catalyze the interconversion of alpha-D-glucose 1-phosphate and alpha-D-glucose 6-phosphate, although at a much lower rate. alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K03431:glmM; phosphoglucosamine mutase [EC:5.4.2.10] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 823552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188961 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 808762 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQDDILK MGYG000002494_02921 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0060@1|root,COG0060@2|Bacteria,1MVBQ@1224|Proteobacteria,1RMTF@1236|Gammaproteobacteria,3XNGC@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) 1.0 ileS 1.0 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 1.0 6.1.1.5 1.0 ko:K01870 1.0 ko00970,map00970 1.0 M00359,M00360 1.0 R03656 1.0 RC00055,RC00523 1.0 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 iG2583_1286.G2583_0027,iPC815.YPO0475 1.0 Acetyltransf_3,Anticodon_1,FAD_syn,Flavokinase,tRNA-synt_1,zf-FPG_IleRS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_02921 1.0 isoleucine--tRNA ligase. isoleucyl-tRNA synthetase. - ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl- tRNA(Ile). 1.0 1.0 1.0 1.0 Aminoacyl-tRNA biosynthesis 1.0 K01870:IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2288668 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2715538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQDGHLADFAFQC(Carbamidomethyl)TGNPHAHANIYK MGYG000000171_01275 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A sp900120195|m__MGYG000000171 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3WS7A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Glucose dehydrogenase C-terminus 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000171_01275 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 262804 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236444 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 779903 0 0 806061 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQDLNSEQLNK MGYG000001313_01935 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides eggerthii|m__MGYG000001313 1.0 COG1629@1|root,COG3188@1|root,COG1629@2|Bacteria,COG3188@2|Bacteria,4PKAS@976|Bacteroidetes,2FWM7@200643|Bacteroidia,4ANM7@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 NPU 1.0 Psort location OuterMembrane, score 9.49 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001313_01935 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321033 0 0 0 0 467589 0 0 0 0 509489 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1000109 0 0 0 0 757252 0 0 0 0 747764 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324286 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQDTVDR MGYG000000271_03640 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000000271_03640 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 487083 0 0 0 0 0 958974 0 0 0 828116 996483 0 0 0 0 0 0 0 0 831572 0 0 0 920308 570648 777553 0 0 1015838 0 0 0 0 0 0 0 0 213086 0 0 0 0 0 233144 0 0 0 396350 0 0 0 0 0 0 0 0 0 210613 0 0 0 0 162816 100186 0 0 176781 0 0 0 0 0 0 174774 0 152057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174672 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQDTVDRITK MGYG000000271_03640 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000000271_03640 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQDYMLQEVQR MGYG000001315_01195 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3XYSW@572511|Blautia 1.0 186801|Clostridia 1.0 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 - 1.0 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 1.0 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000001315_01195 1.0 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 657461 0 0 0 0 0 0 0 593827 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467613 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 343529 0 0 0 0 367828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 167098 0 0 492198 0 0 0 0 0 0 0 195514 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 501571 0 0 0 0 772935 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1170794 0 0 0 0 0 +AAQEAAANQDTR MGYG000003697_01634 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0653@1|root,COG0653@2|Bacteria,4NF7C@976|Bacteroidetes,2FMVF@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 U 1.0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane 1.0 secA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 1.0 - 1.0 ko:K03070 1.0 ko02024,ko03060,ko03070,map02024,map03060,map03070 1.0 M00335 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02044 1.0 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 1.0 - 1.0 - 1.0 Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01634 1.0 - - - - 1.0 1.0 1.0 1.0 Quorum sensing|Protein export|Bacterial secretion system 1.0 K03070:secA; preprotein translocase subunit SecA [EC:7.4.2.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1704439 0 0 1314102 0 641514 0 0 1324832 0 756164 0 508139 1221362 0 1766060 0 0 0 1764799 715524 1578068 0 0 0 2027660 567724 0 750253 777986 1176116 571170 603440 0 0 1466813 0 0 167576 0 0 0 0 0 0 0 0 0 0 0 205702 0 0 0 0 0 0 0 0 136252 0 0 0 0 299057 0 534963 0 147553 266245 0 0 0 158537 +AAQEAGDTDKVKK MGYG000000022_02302 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,3WGY6@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 O 1.0 Molecular chaperone. Has ATPase activity 1.0 htpG 1.0 - 1.0 - 1.0 ko:K04079 1.0 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 HATPase_c,HATPase_c_3,HSP90 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_02302 1.0 - - - - 1.0 1.0 1.0 1.0 Protein processing in endoplasmic reticulum|PI3K-Akt signaling pathway|Necroptosis|Antigen processing and presentation|NOD-like receptor signaling pathway|Plant-pathogen interaction|IL-17 signaling pathway|Th17 cell differentiation|Progesterone-mediated oocyte maturation|Estrogen signaling pathway|Pathways in cancer|Prostate cancer|Fluid shear stress and atherosclerosis 1.0 K04079:HSP90A, htpG; molecular chaperone HtpG 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 185749 0 0 0 0 326574 0 0 0 0 450231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 267320 0 0 0 0 67350 0 0 0 0 276849 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223140 0 0 0 0 386716 0 0 0 0 91588 0 0 0 0 0 0 0 0 0 0 +AAQEALEN(Deamidated)GTGK MGYG000002455_01614;MGYG000001780_00268;MGYG000004876_01420;MGYG000001346_00849;MGYG000003681_00158 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,4AKGG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_01614 0.2 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 391486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 722902 0 1110648 1194936 0 1241872 0 0 0 1359082 1136369 1603636 0 0 0 0 0 384681 0 0 0 1213750 555846 897315 0 1150373 0 584781 0 971855 0 0 1135873 1183863 0 0 1280036 1040492 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 64773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220706 0 0 337142 0 197409 0 0 0 264848 357621 489825 0 0 0 0 0 0 0 0 0 251456 0 0 0 181054 0 387873 0 259130 0 0 0 423915 0 0 395218 228574 227040 0 0 0 0 166529 0 0 0 0 894434 0 0 0 0 0 0 540888 0 0 0 98379 414581 0 0 244054 0 381697 0 279488 0 0 0 267078 0 0 190588 129845 +AAQEALENGTGK MGYG000002455_01614;MGYG000001780_00268;MGYG000004876_01420;MGYG000001346_00849;MGYG000003681_00158 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,4AKGG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_01614 0.2 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 560555 0 0 0 0 0 0 317685 0 0 0 0 235753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 587829 0 733087 331776 0 0 0 0 328149 0 355161 0 0 0 0 636824 0 401248 0 0 491685 0 442781 0 0 0 320537 0 0 0 0 0 0 0 0 0 0 0 0 0 0 779177 0 0 0 0 0 0 992138 0 0 0 0 644531 0 0 0 0 617282 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174255 0 0 0 0 0 0 285833 0 0 0 0 0 0 163985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550259 0 0 1174647 0 0 0 0 488417 0 1748657 0 0 0 0 1103937 0 438013 0 0 785670 0 776289 0 0 0 623115 0 0 0 0 +AAQEEEFSLELR MGYG000000093_03534;MGYG000002506_04281;MGYG000002477_04491;MGYG000002494_03044;MGYG000002323_00741;MGYG000003372_02025;MGYG000001465_03792;MGYG000002504_00584;MGYG000002515_00161;MGYG000003390_04763;MGYG000002534_00996;MGYG000002535_03440 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0008@1|root,COG0008@2|Bacteria,1MUN7@1224|Proteobacteria,1RMYQ@1236|Gammaproteobacteria,3ZK8D@590|Salmonella 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon 1.0 gluQ 1.0 GO:0000166,GO:0002097,GO:0003674,GO:0005488,GO:0005524,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 1.0 - 1.0 ko:K01894 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01007,ko03016 1.0 - 1.0 - 1.0 - 1.0 tRNA-synt_1c 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000093_03534 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K01894:gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-] 1.0 none 1.0 596089 559656 296051 0 484713 847588 561554 828340 0 0 0 784783 0 0 377821 0 0 0 659705 573366 520770 794064 0 1080944 950791 634940 669899 0 765152 1013052 0 0 688436 642223 700891 0 555848 463509 977674 1030501 1306306 0 1160230 1957023 1193660 1150772 0 0 0 1303822 0 0 1116356 0 0 0 1476675 1196003 1451897 2697319 0 1728229 1304377 1073321 1072521 0 1814638 1392504 0 0 1161299 1129843 1150503 0 841116 1266437 691492 382040 404625 0 678711 1169441 268010 443711 0 0 0 462597 0 0 668560 0 0 0 0 494999 377473 983164 0 923818 483919 445964 725744 0 662177 472247 0 0 507214 637012 369510 0 167867 436866 826415 679484 748913 0 1003737 1056533 1168904 1116486 0 0 0 849682 0 0 947296 0 0 0 961631 774870 991616 629620 0 920864 1150210 991884 822903 0 836975 1081024 0 0 697830 1432431 1280918 0 665493 528633 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 210862 0 0 0 0 0 0 0 0 +AAQEGIVFSFK MGYG000002455_04126 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides cellulosilyticus|m__MGYG000002455 1.0 COG1070@1|root,COG1070@2|Bacteria,4NFBZ@976|Bacteroidetes,2FPIS@200643|Bacteroidia,4AMYR@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Carbohydrate kinase, FGGY family protein 1.0 xylB_2 1.0 - 1.0 2.7.1.17 1.0 ko:K00854 1.0 ko00040,ko01100,map00040,map01100 1.0 M00014 1.0 R01639 1.0 RC00002,RC00538 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FGGY_C,FGGY_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002455_04126 1.0 xylulokinase. Xylulose kinase. - ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+). 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Metabolic pathways 1.0 K00854:xylB, XYLB; xylulokinase [EC:2.7.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 414039 0 0 0 0 0 0 0 0 0 465651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 800532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1320747 0 0 0 0 1069679 0 0 0 0 968055 0 0 0 0 0 0 0 0 0 0 +AAQEKLTQSAQK MGYG000000271_02474;MGYG000004271_00836 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia 1.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia 1.0 186801|Clostridia 1.0 O 1.0 Heat shock 70 kDa protein 1.0 dnaK 1.0 - 1.0 - 1.0 ko:K04043 1.0 ko03018,ko04212,ko05152,map03018,map04212,map05152 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.0 1.A.33.1 1.0 - 1.0 - 1.0 HSP70,MreB_Mbl 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_02474 0.5 - - - - 1.0 1.0 1.0 1.0 RNA degradation|Longevity regulating pathway - worm|Tuberculosis 1.0 K04043:dnaK, HSPA9; molecular chaperone DnaK 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQELFDVSQVR MGYG000002494_01268;MGYG000002477_03573;MGYG000003372_00988;MGYG000002534_01961 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0655@1|root,COG0655@2|Bacteria,1MW7N@1224|Proteobacteria,1S23B@1236|Gammaproteobacteria 0.75 1236|Gammaproteobacteria 1.0 S 1.0 Belongs to the WrbA family 0.75 wrbA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016043,GO:0016491,GO:0016651,GO:0016655,GO:0022607,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 1.6.5.2 1.0 ko:K03809 1.0 ko00130,ko01110,map00130,map01110 1.0 - 1.0 R02964,R03643,R03816 1.0 RC00819 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FMN_red 1.0 - 1.0 AA6 1.0 AA6 1.0 - 1.0 MGYG000002494_01268 0.25 NAD(P)H dehydrogenase (quinone). vitamin-K reductase. The enzyme catalyzes a two-electron reduction and has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone.-!-The animal, but not the plant, form of the enzyme is inhibited by dicoumarol.-!-Formerly EC 1.6.99.2. (1) a quinone + H(+) + NADH = a quinol + NAD(+). (2) a quinone + H(+) + NADPH = a quinol + NADP(+). 1.0 1.0 1.0 1.0 Ubiquinone and other terpenoid-quinone biosynthesis|Biosynthesis of secondary metabolites 1.0 K03809:wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] 1.0 none 1.0 0 0 0 0 0 139169 367640 0 349690 494359 0 0 0 0 0 277364 291174 0 560391 0 0 507894 0 431494 416882 0 0 0 917497 0 0 0 367235 0 0 0 0 632369 0 0 824167 0 0 2058336 499810 0 534016 676362 0 0 0 0 0 574816 908572 0 864352 0 0 2668766 0 1648765 614870 0 0 0 976429 0 0 0 977369 0 0 0 0 559687 0 0 0 0 0 527066 0 0 0 233759 0 0 0 0 0 365162 0 0 348020 0 0 427136 0 229816 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 384232 0 0 0 0 0 0 0 0 0 0 0 0 478785 0 0 0 0 0 483562 0 0 0 0 0 0 439398 0 0 0 313464 0 0 0 0 865539 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQEMLEK MGYG000001378_04145;MGYG000000196_02254 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia,4AKGG@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_04145 0.5 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 1051207 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1305934 0 1378544 0 0 0 0 0 0 0 1598398 0 0 0 1131778 0 0 0 0 0 0 0 1375572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 546110 0 1287518 0 0 0 0 0 0 0 1121352 0 0 0 1279303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 978401 0 892209 0 0 0 0 0 0 0 801201 0 0 0 0 0 0 0 0 0 0 0 862237 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1039820 0 1166708 0 0 0 0 0 0 0 1767832 0 0 0 1870494 0 0 0 0 0 0 0 1523266 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1441537 0 1265440 0 0 0 0 0 0 0 445364 0 0 0 697578 0 0 +AAQEQLATAK MGYG000002293_00897 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,2FNVT@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 N 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02557 1.0 ko02030,ko02040,map02030,map02040 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02000,ko02035 1.0 1.A.30.1 1.0 - 1.0 - 1.0 OmpA,ZapB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00897 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis|Flagellar assembly 1.0 K02557:motB; chemotaxis protein MotB 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 187263 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1971115 0 0 0 3949055 0 0 0 0 0 0 0 0 0 1459939 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQEQLSSTKK MGYG000003697_02770 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG1360@1|root,COG1360@2|Bacteria,4NF2Y@976|Bacteroidetes,2FNVT@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 N 1.0 OmpA family 1.0 - 1.0 - 1.0 - 1.0 ko:K02557 1.0 ko02030,ko02040,map02030,map02040 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02000,ko02035 1.0 1.A.30.1 1.0 - 1.0 - 1.0 OmpA,ZapB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_02770 1.0 - - - - 1.0 1.0 1.0 1.0 Bacterial chemotaxis|Flagellar assembly 1.0 K02557:motB; chemotaxis protein MotB 1.0 none 1.0 0 0 412415 0 0 402215 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 663977 0 828986 0 0 0 0 0 0 0 0 0 0 0 0 0 560669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 637675 0 0 536606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 775081 0 786921 0 0 0 0 0 0 705356 0 467525 0 0 0 0 858169 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQFVASHD(Asp->Pro)GEVC(Carbamidomethyl)PAK MGYG000004763_00297 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__CAG-462|s__CAG-462 sp900291465|m__MGYG000004763 1.0 COG0450@1|root,COG0450@2|Bacteria,4NEDT@976|Bacteroidetes,2FMG5@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 O 1.0 Peroxiredoxin 1.0 ahpC 1.0 - 1.0 1.11.1.15 1.0 ko:K03386 1.0 ko04214,map04214 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 1-cysPrx_C,AhpC-TSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004763_00297 1.0 and 1.11.1.29. - - - 1.0 1.0 1.0 1.0 Apoptosis - fly 1.0 K03386:PRDX2_4, ahpC; peroxiredoxin 2/4 [EC:1.11.1.24] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1795468 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQGGINAAK MGYG000004797_00778;MGYG000003697_02283;MGYG000004006_00370;MGYG000001461_00141;MGYG000001302.1_00465;MGYG000002478_01127;MGYG000001337_00566;MGYG000000074_01707;MGYG000001346_01988;MGYG000002203_00448;MGYG000000236_03409;MGYG000003681_02554;MGYG000001489_01892;MGYG000000054_01799;MGYG000003363_00071;MGYG000004757_00444;MGYG000001415_01060;MGYG000001480_02130;MGYG000000098_00498;MGYG000002293_02708;MGYG000003701_02816;MGYG000002438_01315;MGYG000001666_01263;MGYG000000003_02554;MGYG000004876_01120;MGYG000001345_04416;MGYG000002905_00555;MGYG000000354_00310;MGYG000000303_00634;MGYG000001789_02670;MGYG000001313_00346;MGYG000001546_01596;MGYG000004848_01076;MGYG000000414_00982;MGYG000000196_02827 domain d__Bacteria 1.0 COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,2FM67@200643|Bacteroidia,4AN3V@815|Bacteroidaceae 0.4857142857142857 976|Bacteroidetes 0.9428571428571428 C 1.0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit 0.4857142857142857 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 0.9428571428571428 ko:K00239 0.9428571428571428 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 0.9428571428571428 M00009,M00011,M00149,M00173,M00374,M00376 0.9428571428571428 R02164 0.9428571428571428 RC00045 0.9428571428571428 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004797_00778 0.02857142857142857 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 0.9428571428571428 0.9428571428571428 0.9428571428571428 0.9428571428571428 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Legionellosis 0.9428571428571428 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 0.9428571428571428 none 1.0 0 0 1748004 0 1928035 1308846 0 1430659 0 0 0 1397952 0 0 0 0 1664041 0 1626218 0 1392113 2316856 0 1836282 1438300 0 0 0 0 1668361 0 1840138 1331963 0 0 1296151 0 2457002 0 0 1212969 0 1557870 1090704 0 1771448 0 0 0 1591408 2038541 0 0 0 1512953 0 1449396 0 1337045 1146119 0 780685 1033897 0 0 0 0 1546035 0 1425871 885530 0 0 1292069 0 771867 0 0 1595342 0 1616446 1927906 0 1667189 0 0 0 1630010 1722787 0 0 0 1191701 0 1195335 0 2014978 1183168 0 1430873 1029649 0 0 0 0 921806 0 1372147 1597614 0 0 1834714 0 1658246 0 0 2737867 0 3004680 2342726 0 1863362 0 0 0 2579417 1496921 0 0 0 2041682 0 1659774 0 745502 3870161 0 2920957 1498432 0 0 0 0 1821020 0 2226929 1593883 0 0 746425 0 3756105 0 0 610223 0 793219 517875 0 647304 0 0 0 559418 937995 0 0 0 403873 0 955565 0 1462383 1099836 0 1096802 779795 0 0 0 0 1200581 0 597012 709799 0 0 519292 0 496632 +AAQGGLSTILFEK MGYG000002438_01509 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1249@1|root,COG1249@2|Bacteria,4NDVC@976|Bacteroidetes,2FM8Y@200643|Bacteroidia,22WU2@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Dihydrolipoyl dehydrogenase 1.0 lpdA 1.0 - 1.0 1.8.1.4 1.0 ko:K00382 1.0 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 1.0 M00009,M00011,M00036,M00307,M00532 1.0 R00209,R01221,R01698,R03815,R07618,R08549 1.0 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 1.0 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Pyr_redox_2,Pyr_redox_dim 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_01509 1.0 dihydrolipoyl dehydrogenase. L-protein. A component of the multienzyme 2-oxo-acid dehydrogenase complexes.-!-In the pyruvate dehydrogenase complex, it binds to the core of EC 2.3.1.12 and catalyzes oxidation of its dihydrolipoyl groups.-!-It plays a similar role in the oxoglutarate and 3-methyl-2- oxobutanoate dehydrogenase complexes.-!-Another substrate is the dihydrolipoyl group in the H-protein of the glycine-cleavage system, in which it acts, together with EC 1.4.4.2 and EC 2.1.2.10 to break down glycine.-!-It can also use free dihydrolipoate, dihydrolipoamide or dihydrolipoyllysine as substrate.-!-Was first shown to catalyze the oxidation of NADH by methylene blue; this activity was called diaphorase.-!-The glycine cleavage system is composed of four components that only loosely associate: the P protein (EC 1.4.4.2), the T protein (EC 2.1.2.10), the L protein (EC 1.8.1.4) and the lipoyl-bearing H protein.-!-Formerly EC 1.6.4.3. N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + NAD(+) = H(+) + N(6)-[(R)- lipoyl]-L-lysyl-[protein] + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Glycine, serine and threonine metabolism|Valine, leucine and isoleucine degradation|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00382:DLD, lpd, pdhD; dihydrolipoyl dehydrogenase [EC:1.8.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 297218 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 233426 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 346375 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 999529 0 0 0 0 0 0 0 0 0 0 679435 0 0 0 0 0 0 +AAQGGMQASLANVIK MGYG000003022_01475;MGYG000003352_00541 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,1KJ0V@119065|unclassified Burkholderiales 1.0 28216|Betaproteobacteria 1.0 C 1.0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily 1.0 sdhA 1.0 - 1.0 1.3.5.1,1.3.5.4 1.0 ko:K00239,ko:K00244 1.0 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 1.0 M00009,M00011,M00149,M00150,M00173,M00374,M00376 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003022_01475 0.5 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Two-component system|Legionellosis 1.0 K00239:sdhA, frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]|K00244:frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 529166 0 259079 636716 0 336027 432732 0 725303 452753 0 670328 0 540355 141830 140815 557970 0 0 449689 0 370487 0 355371 0 0 449267 0 0 584725 0 388329 0 650558 0 0 434871 0 823883 582698 1041156 1030649 929815 924587 831348 1520562 832036 986647 1218269 980864 0 862100 903837 775088 839757 0 884527 695254 0 849459 0 914721 0 890118 941336 0 0 1038920 0 840347 839004 800742 1613882 841413 767939 665823 0 0 479783 231194 0 426119 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 274556 0 0 0 0 535190 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 237776 0 0 0 0 280018 319232 0 430257 0 0 0 0 374354 334368 0 314632 0 420649 313643 0 0 0 296616 0 336770 319704 0 0 304276 0 0 0 395189 0 302988 287221 0 +AAQGGMQASLGNVIK MGYG000004704_00059;MGYG000001410_00319 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Sutterella 1.0 COG1053@1|root,COG1053@2|Bacteria,1MU5M@1224|Proteobacteria,2VHM6@28216|Betaproteobacteria,4PQQW@995019|Sutterellaceae 1.0 28216|Betaproteobacteria 1.0 C 1.0 Fumarate reductase flavoprotein C-term 1.0 frdA 1.0 - 1.0 1.3.5.4 1.0 ko:K00244 1.0 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 1.0 M00009,M00011,M00150,M00173 1.0 R02164 1.0 RC00045 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD_binding_2,Succ_DH_flav_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004704_00059 0.5 succinate dehydrogenase. succinic dehydrogenase. A complex generally comprising an FAD-containing component that also binds the carboxylate substrate (A subunit), a component that contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S], and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component (C, or C and D subunits) that is also the site of the interaction with quinones.-!-The enzyme is found in the inner mitochondrial membrane in eukaryotes and the plasma membrane of bacteria and archaea, with the hydrophilic domain extending into the mitochondrial matrix and the cytoplasm, respectively.-!-Under aerobic conditions the enzyme catalyzes succinate oxidation, a key step in the citric acid (TCA) cycle, transferring the electrons to quinones in the membrane, thus linking the TCA cycle with the aerobic respiratory chain (where it is known as complex II).-!-Under anaerobic conditions the enzyme functions as a fumarate reductase, transferring electrons from the quinol pool to fumarate, and participating in anaerobic respiration with fumarate as the terminal electron acceptor.-!-The enzyme interacts with the quinone produced by the organism, such as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone, rhodoquinone etc. Some of the enzymes contain two heme subunits in their membrane anchor subunit.-!-These enzymes catalyze an electrogenic reaction and are thus classified as EC 7.1.1.12.-!-Formerly EC 1.3.5.4. a quinone + succinate = a quinol + fumarate. 1.0 1.0 1.0 1.0 Citrate cycle (TCA cycle)|Oxidative phosphorylation|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Two-component system 1.0 K00244:frdA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1] 1.0 none 1.0 0 0 0 0 0 0 0 374209 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 430512 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258314 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 517106 612207 0 447416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496786 0 0 0 0 0 0 1947609 0 0 0 0 1203878 0 0 0 0 1166996 0 0 0 0 919817 0 0 852931 0 964150 0 1084237 883322 0 0 978130 2279160 0 1396935 0 +AAQGILTVR MGYG000000463_01481;MGYG000002114_00088;MGYG000002229_00282;MGYG000002006_01658;MGYG000004482_00393;MGYG000004594_00959;MGYG000004667_00970;MGYG000002727_00240;MGYG000001319_00729;MGYG000004680_00577;MGYG000000145_01088;MGYG000004760_00878;MGYG000002670_01671;MGYG000001688_03814;MGYG000001698_00702;MGYG000002926_01683;MGYG000001757_01805;MGYG000002143_00035;MGYG000002057_00345;MGYG000000728_00587;MGYG000002103_01314;MGYG000000084_02423;MGYG000000205_02701;MGYG000000152_05136;MGYG000004663_01541;MGYG000004866_01724;MGYG000002059_01602;MGYG000004380_01725;MGYG000002025_01833;MGYG000004475_00310;MGYG000003422_01232;MGYG000000242_00224;MGYG000002139_00077;MGYG000002794_01254;MGYG000004718_01489;MGYG000004517_00262;MGYG000001733_00637;MGYG000000175_01356;MGYG000002552_02286;MGYG000000404_01435;MGYG000000387_01345;MGYG000004784_01123;MGYG000002492_01692;MGYG000004845_02015;MGYG000001439_01567;MGYG000000371_01679;MGYG000000489_00801;MGYG000000281_03419;MGYG000000142_02834;MGYG000002702_00763;MGYG000002099_01951;MGYG000004487_00114;MGYG000000233_02503;MGYG000000031_02405;MGYG000001619_00896;MGYG000000179_00100;MGYG000000690_00823;MGYG000003074_00103;MGYG000000255_02207;MGYG000001564_02842;MGYG000000198_00250;MGYG000002945_01502;MGYG000001496_03326;MGYG000003921_01571;MGYG000001748_00979;MGYG000001675_00187;MGYG000003628_00298;MGYG000001646_00500;MGYG000003656_02122;MGYG000002925_01270;MGYG000002126_00460;MGYG000003694_01656;MGYG000001637_01169;MGYG000000087_02439 domain d__Bacteria 1.0 COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3WG9W@541000|Ruminococcaceae 0.17567567567567569 186801|Clostridia 1.0 G 0.9459459459459459 Belongs to the PEP-utilizing enzyme family 0.6756756756756757 ppdK 0.9459459459459459 - 1.0 2.7.9.1 0.9459459459459459 ko:K01006 0.9459459459459459 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 0.9459459459459459 M00169,M00171,M00172,M00173 0.9459459459459459 R00206 0.9459459459459459 RC00002,RC00015 0.9459459459459459 ko00000,ko00001,ko00002,ko01000 0.9459459459459459 - 0.9459459459459459 - 1.0 - 1.0 PEP-utilizers,PEP-utilizers_C,PPDK_N 0.9459459459459459 - 1.0 - 1.0 - 1.0 GT1 0.9459459459459459 MGYG000000463_01481 0.013513513513513514 pyruvate, phosphate dikinase. pyruvate,phosphate dikinase. - ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate. 0.9459459459459459 0.9459459459459459 0.9459459459459459 0.9459459459459459 Pyruvate metabolism|Carbon fixation in photosynthetic organisms|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 0.9459459459459459 K01006:ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1] 0.9459459459459459 none 1.0 3194457 2831118 3464559 3115777 3404336 3101604 3042715 4660479 3395673 3894702 5219194 3122776 3216090 3559192 4209264 3476708 4074932 9737069 2372861 3474059 3648671 2808644 9405915 2875471 4012131 3089365 3390734 10799457 3443041 2743033 2966375 2941220 3096229 3649509 4277632 3548755 3522498 3171834 4849352 3986915 6180819 4017071 7298774 2797554 4300692 3750600 3996028 3900634 7128919 2048206 5799007 2830867 3190555 3913948 2319139 24217990 3131213 4092222 3189302 2526948 14835436 3830537 3279461 3508037 5018327 20138796 4293951 2607969 8951235 10864777 7184182 5374210 4969981 5733529 4543391 8731855 11868559 11202468 36027200 13016059 11474867 8326267 10439267 12964486 9833894 12465320 13896375 9744785 15144721 12003260 12831846 19123376 11011756 7061913 10789991 10700858 9685608 11676132 12455446 8916316 12520783 11457574 12801568 16690068 12573170 12492808 12551275 12065826 33674292 14754883 13735699 8828348 13018994 32946203 1428224 1342943 1596142 1267241 1413992 1264644 1385486 1037554 1341019 1546574 1566979 994107 1163788 1509715 1429381 1761511 1603809 1419336 875723 1776190 1275324 1950449 1516525 1787408 906546 924906 1738984 666393 2069121 473569 2573652 948984 1865527 842133 930020 1202944 1193690 2041317 2551411 1529528 4495656 2531390 2108584 5184368 3591264 3111450 2563877 2928281 2350566 2139749 1180574 3600781 2250076 1862440 2067734 3907961 2595004 1997662 2058144 4805364 6018939 3983363 2753311 1836154 2792981 6032711 4272997 1184546 3399268 2107595 8082641 3299839 2841989 2308297 1690592 4281867 +AAQGMWQDR MGYG000000802_01645;MGYG000003274_00635;MGYG000003266_00911 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4CVSZ@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 J 1.0 Belongs to the bacterial ribosomal protein bL17 family 1.0 rplQ 1.0 - 1.0 - 1.0 ko:K02879 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L17 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000802_01645 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02879:RP-L17, MRPL17, rplQ; large subunit ribosomal protein L17 1.0 none 1.0 0 2694326 0 0 372653 0 0 0 0 0 560957 0 1422720 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 358781 0 0 313986 0 0 0 0 0 622830 0 808956 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 215540 0 0 378817 0 0 0 0 0 0 0 406898 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 458759 0 0 999948 0 0 0 0 0 1661249 0 2578690 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 352197 0 0 420573 0 0 0 0 0 598433 0 126552 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQGNNFGTVLIPEGLIEFIPAMK MGYG000004876_02004;MGYG000002455_02781 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 MGYG000004876_02004 0.5 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7324062 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 26192594 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQGNNFGTVLIPEGLIEFIPAMKR MGYG000004876_02004;MGYG000004797_01062;MGYG000001780_01920 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 MGYG000004876_02004 0.3333333333333333 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 1325382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1714109 0 0 0 0 0 0 0 0 0 0 0 2342888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 21596852 0 0 0 0 0 0 0 3280869 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5255623 0 0 0 0 0 0 0 +AAQGNNFGTVLIPEGLVEFIPAMKR MGYG000003681_01737;MGYG000000243_02424;MGYG000000196_00779 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0205@1|root,COG0205@2|Bacteria,4NIKT@976|Bacteroidetes,2FNYX@200643|Bacteroidia,4AM9P@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 H 1.0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions 1.0 pfp 1.0 - 1.0 2.7.1.11,2.7.1.90 1.0 ko:K00895,ko:K21071 1.0 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 1.0 - 1.0 R00756,R00764,R02073,R03236,R04779 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PFK 1.0 - 1.0 - 1.0 - 1.0 GT106 1.0 MGYG000003681_01737 0.3333333333333333 6-phosphofructokinase. | diphosphate--fructose-6-phosphate 1-phosphotransferase. phosphohexokinase. | pyrophosphate--fructose 6-phosphate 1-phosphotransferase. The enzyme from rabbit muscle displays absolute stereoselectivity for the beta-anomer of D-fructofuranose 6-phosphate.-!-D-tagatose 6-phosphate and sedoheptulose 7-phosphate can act as acceptors.-!-UTP, CTP and ITP can act as donors.-!-Not identical with EC 2.7.1.105. ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6- bisphosphate + H(+). | beta-D-fructose 6-phosphate + diphosphate = beta-D-fructose 1,6- bisphosphate + H(+) + phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Fructose and mannose metabolism|Galactose metabolism|Methane metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00895:pfp, PFP; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]|K21071:pfk, pfp; ATP-dependent phosphofructokinase / diphosphate-dependent phosphofructokinase [EC:2.7.1.11 2.7.1.90] 1.0 none 1.0 0 0 1497726 0 1667695 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 14567704 0 0 0 0 0 0 0 0 0 3972171 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10755160 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQGQNVAR MGYG000004525_00228;MGYG000002670_01511;MGYG000000997_00552;MGYG000000489_01023;MGYG000002727_00924;MGYG000000280_01473;MGYG000002143_01933;MGYG000004487_00561;MGYG000003215_01534;MGYG000000389_02151;MGYG000004271_00231;MGYG000001616_02334;MGYG000000245_02019;MGYG000000271_02104;MGYG000001637_02269;MGYG000001711_01126;MGYG000001186_01723;MGYG000002517_00540;MGYG000003694_00877;MGYG000000153_01463;MGYG000004475_01257;MGYG000002492_00657 domain d__Bacteria 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.6818181818181818 186801|Clostridia 0.9545454545454546 I 1.0 Belongs to the thiolase family 0.6818181818181818 thlA 0.9545454545454546 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004525_00228 0.045454545454545456 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 3508440 2511029 784078 2492207 3163089 655332 752658 2500920 2638599 3400973 1110053 2872812 1760483 4091456 6872611 1203378 1148337 934166 3799235 366499 2843474 562691 646036 878224 3006449 3440318 2407475 784546 985773 3687771 1196172 424416 1194501 3726401 1814005 1471135 2216270 1590613 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3353658 232405 1670218 650375 513932 357476 1093770 777870 1274719 1837992 1430376 391782 1196289 1530858 1596596 1247216 1442636 0 730398 846836 1181906 265828 182385 1846100 2020035 3845146 1025478 272072 411382 542240 573422 159885 2919993 818570 1323281 1989606 1443993 3328890 1437777 1012529 870778 7851845 631566 2632048 15693514 5459159 15141397 3640235 4092338 1700090 5263440 7567521 6922211 1733667 2237395 913979 10176779 13305053 11505869 1155876 938396 1247053 8071725 5055946 2876480 997203 1962819 2197718 3146076 1995367 1296005 1062574 3992044 6646376 6068827 647429 171485 0 0 217447 0 60725 122699 0 84067 134808 0 27927 129550 0 0 0 0 0 186692 187214 41917 0 0 197241 196953 164057 208425 0 159602 362757 87917 0 0 0 260728 131454 454264 165519 +AAQGTVIEAR MGYG000002156_00834;MGYG000002720_01209 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,2N6M6@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex 1.0 infB 1.0 - 1.0 - 1.0 ko:K02519 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,IF-2,IF2_N 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002156_00834 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02519:infB, MTIF2; translation initiation factor IF-2 1.0 none 1.0 637048 0 454950 0 0 0 0 0 0 0 0 0 0 0 0 1241350 0 0 0 0 0 0 0 0 0 439142 0 0 0 0 0 0 632533 0 0 0 570822 1130642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489199 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 957141 564553 881659 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 628205 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 701879 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 474894 0 0 0 0 0 +AAQGW(Trp->Ser)AEEDGTWVYYDR MGYG000000198_05887 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster citroniae|m__MGYG000000198 1.0 COG5263@1|root,COG5263@2|Bacteria,1UYGF@1239|Firmicutes,24DXJ@186801|Clostridia,21ZAM@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Putative cell wall binding repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CW_binding_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000198_05887 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 408236 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 610806 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 780068 0 0 0 0 552829 0 0 533382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 694212 0 0 0 0 1119505 0 0 813826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 802217 0 0 0 0 584027 0 0 2294558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQIIEPALTDPSTANDPETWK MGYG000003693_01133 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG4783@1|root,COG4783@2|Bacteria,4P1TE@976|Bacteroidetes,2G0AS@200643|Bacteroidia,4AMX1@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 tetratricopeptide repeat 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MbeB_N,TPR_1,TPR_11,TPR_16,TPR_17,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_01133 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 729264 0 0 0 0 1092874 0 0 0 0 774340 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQIISR MGYG000000142_02731;MGYG000001338_01296;MGYG000002528_00119;MGYG000001698_03439;MGYG000002275_01873;MGYG000000205_02543;MGYG000001627_00963;MGYG000000262_01832;MGYG000001770_01218;MGYG000002834_01893;MGYG000002108_00627;MGYG000002517_01686;MGYG000000212_00326;MGYG000002492_01963;MGYG000000029_00187;MGYG000000196_00899;MGYG000000280_02029;MGYG000000233_02118;MGYG000001599_00424;MGYG000000707_02290;MGYG000001707_00757;MGYG000001346_01121;MGYG000000215_01600;MGYG000003937_01695;MGYG000001871_01775;MGYG000003425_04615;MGYG000004733_02764;MGYG000002293_01605 domain d__Bacteria 1.0 2C4R5@1|root,2Z7JK@2|Bacteria,4NHGV@976|Bacteroidetes,2FMRU@200643|Bacteroidia,4AMEG@815|Bacteroidaceae 0.21428571428571427 186801|Clostridia 0.5 S 0.9285714285714286 Psort location Cytoplasmic, score 8.96 0.42857142857142855 - 0.9285714285714286 - 1.0 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 - 1.0 - 1.0 - 1.0 GGGtGRT 0.9285714285714286 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_02731 0.03571428571428571 - - - - 0.9285714285714286 0.9285714285714286 0.9285714285714286 0.9285714285714286 - 0.9285714285714286 - 0.9285714285714286 none 1.0 0 0 186253 1854462 317275 0 2333953 0 91343 0 0 1750091 0 254570 0 285784 0 0 0 0 0 0 0 0 663738 0 0 0 0 0 2071688 0 1892111 0 0 155150 0 1881763 0 0 238626 455583 171871 0 866437 471972 351316 0 357056 167872 0 224708 0 1471865 0 0 293483 438875 0 0 0 0 1061190 0 0 0 1396986 0 756051 0 1439465 0 381372 654769 0 1136320 0 0 1491699 682836 869340 0 720980 619598 1359725 0 997871 532770 0 971370 706566 1010617 0 0 522858 811031 0 0 0 0 1211244 0 0 0 926207 0 842999 0 873751 0 551449 688363 0 1103481 0 0 1415659 2160560 1498290 0 2128979 1780318 1452188 0 1519302 1459361 0 1198782 1819674 1082708 0 0 1141297 1251440 0 0 0 0 984264 0 0 0 1553688 0 967455 0 1418726 0 2035971 1489702 0 2676158 0 0 1331179 2864948 2321839 0 1467440 0 1174736 0 2870354 507276 0 1315477 2007247 1890564 0 0 1529933 2224194 0 0 0 0 2230383 0 0 0 1203201 0 128813 0 2562220 0 0 2032899 0 2335234 +AAQITTNAAHDTHPVWSPDGK MGYG000000243_00233 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0793@1|root,COG4946@1|root,COG0793@2|Bacteria,COG4946@2|Bacteria,4NGU2@976|Bacteroidetes,2FPGA@200643|Bacteroidia,4ANRZ@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 M 1.0 Tricorn protease homolog 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PD40,PDZ,PDZ_2,Peptidase_S41,Tricorn_C1,Tricorn_PDZ 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00233 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 469907 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1235613 0 0 0 0 1191693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQIWYENDGDLSVLEGK MGYG000003683_01408;MGYG000002469_00124 genus d__Bacteria|p__Actinobacteriota|c__Actinomycetia|o__Actinomycetales|f__Bifidobacteriaceae|g__Bifidobacterium 1.0 COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,4CZBR@85004|Bifidobacteriales 1.0 201174|Actinobacteria 1.0 H 1.0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate 1.0 ilvC 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003683_01408 0.5 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 283784 0 0 0 0 0 0 968929 0 0 0 0 1489344 0 0 0 0 640637 757615 0 0 0 1089566 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 218524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQIYINAR MGYG000003693_00757 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG0235@1|root,COG0235@2|Bacteria,4NIQK@976|Bacteroidetes,2FN5U@200643|Bacteroidia,4AN95@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases 1.0 rhaD 1.0 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 1.0 4.1.2.19 1.0 ko:K01629 1.0 ko00040,ko00051,ko01120,map00040,map00051,map01120 1.0 - 1.0 R01785,R02263 1.0 RC00438,RC00599,RC00603,RC00604 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldolase_II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_00757 1.0 rhamnulose-1-phosphate aldolase. L-rhamnulose-phosphate aldolase. - L-rhamnulose 1-phosphate = (S)-lactaldehyde + dihydroxyacetone phosphate. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Microbial metabolism in diverse environments 1.0 K01629:rhaD; rhamnulose-1-phosphate aldolase [EC:4.1.2.19] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1384090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 579566 0 0 0 0 0 0 0 0 0 1470936 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 353589 0 0 0 0 355344 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQLGGK MGYG000002528_00904 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0277@1|root,COG0277@2|Bacteria,1TPBC@1239|Firmicutes,24A99@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 FAD linked oxidases, C-terminal domain 1.0 glcD1 1.0 - 1.0 1.1.3.15 1.0 ko:K00104 1.0 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 1.0 - 1.0 R00475 1.0 RC00042 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 FAD-oxidase_C,FAD_binding_4 1.0 - 1.0 AA7 1.0 - 1.0 - 1.0 MGYG000002528_00904 1.0 (S)-2-hydroxy-acid oxidase. hydroxy-acid oxidase B. Exists as two major isoenzymes; the A form preferentially oxidizes short-chain aliphatic hydroxy acids; the B form preferentially oxidizes long-chain and aromatic hydroxy acids.-!-The rat isoenzyme B also acts as EC 1.4.3.2.-!-Formerly EC 1.1.3.1. a (2S)-2-hydroxycarboxylate + O2 = a 2-oxocarboxylate + H2O2. 1.0 1.0 1.0 1.0 Glyoxylate and dicarboxylate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments 1.0 K00104:glcD; glycolate dehydrogenase FAD-linked subunit [EC:1.1.99.14] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 604516 0 0 0 0 506429 0 0 0 0 554837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 511179 0 0 0 0 871747 0 0 0 0 613619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1613056 0 0 0 0 157276 0 0 0 0 1296470 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 334575 0 0 0 0 579368 0 0 0 0 631619 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2263127 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQLLNDMHVPFEMNALSAHR MGYG000002281_03334;MGYG000002549_04615;MGYG000001345_00584 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0041@1|root,COG0041@2|Bacteria,4NME9@976|Bacteroidetes,2FMWN@200643|Bacteroidia,4AMDP@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 F 1.0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) 1.0 purE 1.0 - 1.0 5.4.99.18 1.0 ko:K01588 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R07405 1.0 RC01947 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002281_03334 0.3333333333333333 5-(carboxyamino)imidazole ribonucleotide mutase. N(5)-carboxyaminoimidazole ribonucleotide mutase. In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, is required to carry out the single reaction catalyzed by EC 4.1.1.21 in vertebrates.-!-In the absence of EC 6.3.2.6, the reaction is reversible.-!-The substrate is readily converted into 5-amino-1-(5-phospho-D- ribosyl)imidazole by non-enzymic decarboxylation. 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1- (5-phospho-D-ribosyl)imidazole-4-carboxylate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01588:purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18] 1.0 none 1.0 0 0 0 383557 0 0 0 381029 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 489633 0 0 0 647883 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 105567 0 0 0 98422 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92374 0 0 0 94123 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 165855 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQLLVYR MGYG000003074_00587;MGYG000004740_00273;MGYG000001617_02045 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,27K1G@186928|unclassified Lachnospiraceae 0.3333333333333333 186801|Clostridia 1.0 I 0.6666666666666666 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003074_00587 0.3333333333333333 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 306313 772105 0 480257 0 0 0 1408508 0 0 581849 617184 381024 0 0 0 0 0 0 419710 0 0 1403773 0 0 0 1108157 0 0 0 0 572298 0 0 333642 0 2064634 0 793041 1627627 0 1158838 0 1390994 1172931 1650526 937814 0 1015843 1190843 1249375 265784 0 0 1269247 0 0 745897 0 1445455 1300278 1578031 2187510 0 1136740 1332291 1305580 0 1167995 1772450 0 1895887 1499826 988847 915083 0 788608 1183663 0 706136 0 931587 733013 1181729 608120 0 814484 1020842 1010152 775017 0 0 803597 0 0 1016090 0 825938 961143 924432 1204176 0 1067127 791142 518974 0 1102590 1429616 0 735961 963897 757928 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 973442 0 1207574 1574240 0 1009054 0 1451104 1255445 1877334 874836 0 418478 1669829 1439306 1247845 0 0 934282 0 0 1499449 0 2101495 1882566 1091223 1231897 0 2041892 904440 1044950 0 1272868 1515951 0 1482035 1068969 1341146 +AAQLNQEAVDNGLVR MGYG000002517_00279 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG2720@1|root,COG2720@2|Bacteria,1TSH8@1239|Firmicutes,2493X@186801|Clostridia 1.0 186801|Clostridia 1.0 V 1.0 PFAM VanW family protein 1.0 - 1.0 - 1.0 - 1.0 ko:K18346 1.0 ko01502,ko02020,map01502,map02020 1.0 M00651 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko01504 1.0 - 1.0 - 1.0 - 1.0 G5,PG_binding_4,VanW 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_00279 1.0 - - - - 1.0 1.0 1.0 1.0 Vancomycin resistance|Two-component system 1.0 K18346:vanW; vancomycin resistance protein VanW 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 630393 0 0 0 0 0 0 0 806298 0 0 0 0 0 846774 0 0 0 0 0 449622 0 0 0 732164 817913 449981 0 0 0 0 0 0 0 0 824756 878886 0 447261 0 0 0 0 0 0 0 634179 0 0 0 0 0 692021 0 0 0 0 0 454662 0 0 0 534380 496174 633564 0 0 0 0 0 0 0 0 564854 817670 0 +AAQLVADGGYGHTSSLYINVNETEK MGYG000000142_00071 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A massiliensis|m__MGYG000000142 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 9.98 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000142_00071 1.0 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 401077 527510 333580 0 0 0 813973 505401 0 0 853392 0 0 0 0 0 0 0 0 659709 0 0 0 0 0 336189 712128 0 0 0 854722 495681 287197 480831 0 495656 338574 586918 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQLVADGGYGHTSSLYVHPAETEK MGYG000001310_00117;MGYG000002772_01870;MGYG000000249_01522 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter 1.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3WHK1@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 belongs to the iron- containing alcohol dehydrogenase family 1.0 adhE 1.0 - 1.0 1.1.1.1,1.2.1.10 1.0 ko:K04072 1.0 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 1.0 - 1.0 R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 1.0 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Aldedh,Fe-ADH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001310_00117 0.3333333333333333 alcohol dehydrogenase. | acetaldehyde dehydrogenase (acetylating). aldehyde reductase. | aldehyde dehydrogenase (acylating). Acts on primary or secondary alcohols or hemi-acetals with very broad specificity; however the enzyme oxidizes methanol much more poorly than ethanol.-!-The animal, but not the yeast, enzyme acts also on cyclic secondary alcohols.-!-Formerly EC 1.1.1.32. | Also acts, more slowly, on glycolaldehyde, propanal and butanal.-!-In several bacterial species this enzyme forms a bifunctional complex with EC 4.1.3.39.-!-The enzymes from the bacteria Burkholderia xenovorans and Thermus thermophilus also perform the reaction of EC 1.2.1.87.-!-Involved in the meta-cleavage pathway for the degradation of phenols, methylphenols and catechols.-!-NADP(+) can replace NAD(+) but the rate of reaction is much slower. (1) a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH. (2) a secondary alcohol + NAD(+) = a ketone + H(+) + NADH. | acetaldehyde + CoA + NAD(+) = acetyl-CoA + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Fatty acid degradation|Tyrosine metabolism|Pyruvate metabolism|Chloroalkane and chloroalkene degradation|Naphthalene degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Degradation of aromatic compounds 1.0 K04072:adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1] 1.0 none 1.0 0 0 0 0 346945 1166922 0 0 0 432243 440115 0 452196 0 0 666438 352484 315908 0 0 592898 1755770 517510 871359 0 0 0 410604 0 0 389305 0 292218 0 0 0 0 231707 0 0 1027764 0 703238 471137 0 0 0 452482 988169 0 1875458 0 0 2431219 1681605 943037 0 0 479281 267694 299086 351781 0 0 0 542269 0 0 595250 0 886639 0 0 0 0 0 0 0 843115 0 317862 190830 0 0 0 413465 0 0 443923 0 0 703877 381204 0 0 0 340970 317270 424350 388912 0 0 0 339219 0 0 312457 0 795465 0 0 0 0 444799 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQM(Oxidation)AAETATK MGYG000002528_01864;MGYG000003215_00849;MGYG000000142_02038;MGYG000004055_01475;MGYG000000301_00188;MGYG000000171_01879;MGYG000002025_01287;MGYG000003500_00156;MGYG000004735_02050;MGYG000001338_02782;MGYG000004740_00893;MGYG000002286_01563;MGYG000002559_01476;MGYG000000532_01246;MGYG000001141_01291;MGYG000001564_01925;MGYG000000204_02185;MGYG000001637_00006;MGYG000003694_02453;MGYG000003422_00383;MGYG000000356_00499;MGYG000001456.1_01726;MGYG000000216_02331;MGYG000002670_00411;MGYG000000154_01812;MGYG000000139_02422;MGYG000000245_02664;MGYG000000136_02053;MGYG000001186_01087;MGYG000000201_02106;MGYG000002492_00401;MGYG000001493_03358;MGYG000000050_01197;MGYG000000028_01597;MGYG000000153_02068;MGYG000004879_02709 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia 0.5 186801|Clostridia 1.0 J 0.9444444444444444 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.6111111111111112 rpsK 0.6111111111111112 - 1.0 - 1.0 ko:K02948 0.6111111111111112 ko03010,map03010 0.9444444444444444 M00178,M00179 0.9444444444444444 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.9444444444444444 - 1.0 - 1.0 - 0.9444444444444444 Ribosomal_S11 0.6111111111111112 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01864 0.027777777777777776 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.9444444444444444 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 0.6111111111111112 none 1.0 0 0 0 0 707418 0 0 0 0 0 562463 0 0 316692 0 699104 0 1518904 0 504537 0 0 563612 0 0 0 0 711331 0 0 0 0 0 0 0 0 0 0 0 0 0 0 93466 0 0 0 0 0 192529 0 0 0 0 0 0 385509 0 0 0 0 228330 0 0 0 0 455398 0 0 0 0 0 0 0 0 0 0 0 0 0 0 193971 0 0 0 0 0 301489 0 0 225847 0 333927 0 0 0 260937 0 0 118379 0 0 0 0 408256 0 0 0 0 0 0 0 0 0 0 0 0 0 0 560890 0 0 0 0 0 346711 0 0 511913 0 444237 0 393631 0 580312 0 0 0 0 0 0 0 601147 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278939 0 0 0 0 0 77171 0 0 277408 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQM(Oxidation)AAQDC(Carbamidomethyl)AK MGYG000002721_02313;MGYG000001599_01826;MGYG000003420_01325;MGYG000001433_02301;MGYG000001345_04724;MGYG000002218_02495;MGYG000000781_00873;MGYG000003498_00774;MGYG000000696_01638;MGYG000002281_02250;MGYG000003164_01271;MGYG000001835_02485;MGYG000004763_00950;MGYG000003681_02077;MGYG000001370_01720;MGYG000001666_01381;MGYG000001378_05002;MGYG000001787_01778;MGYG000000013_02211;MGYG000001306_02685;MGYG000002935_01264;MGYG000000196_04014;MGYG000002561_02200;MGYG000001337_03864;MGYG000002470_01205;MGYG000001313_00049;MGYG000000054_03883;MGYG000001461_00429;MGYG000001789_00105;MGYG000000174_03501;MGYG000002418_00853;MGYG000000673_01669;MGYG000000273_00381;MGYG000000138_02864;MGYG000003693_00218;MGYG000002438_02233;MGYG000001780_04852;MGYG000003202_00871;MGYG000000044_02999;MGYG000000029_02814;MGYG000002560_00261;MGYG000002762_00888;MGYG000002455_03924;MGYG000001346_01494;MGYG000001871_02152;MGYG000000105_02030;MGYG000003233_00179;MGYG000000236_01762;MGYG000002291_02230;MGYG000004797_02000;MGYG000002275_02092;MGYG000002181_02223;MGYG000003701_04719;MGYG000003521_01403;MGYG000004748_03267;MGYG000001659_00171 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,2FRZD@200643|Bacteroidia,22XN9@171551|Porphyromonadaceae 0.5178571428571429 976|Bacteroidetes 1.0 J 0.5178571428571429 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.5178571428571429 rpsK 0.5178571428571429 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 0.5178571428571429 - 1.0 ko:K02948 0.5178571428571429 ko03010,map03010 0.5178571428571429 M00178,M00179 0.5178571428571429 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.5178571428571429 - 1.0 - 1.0 - 1.0 Ribosomal_S11 0.5178571428571429 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002721_02313 0.017857142857142856 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.5178571428571429 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 0.5178571428571429 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 362406 0 526700 0 0 0 0 279279 0 0 0 0 257246 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 96242 0 0 0 0 350518 0 0 0 0 337948 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 73370 0 0 0 0 0 0 93551 0 0 0 0 101081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 252011 0 320869 0 0 0 0 0 0 0 0 0 284597 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164985 0 0 0 0 106787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQM(Oxidation)MVYR MGYG000000255_01556;MGYG000000205_02133 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,21YI4@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01556 0.5 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 387155 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 863445 0 0 0 0 0 0 667146 1182298 577450 0 0 0 554643 0 0 0 0 0 0 0 0 0 0 0 427328 0 0 0 0 0 0 0 894438 0 658374 484721 0 0 0 0 0 0 0 0 0 637988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 188903 0 0 0 0 0 0 0 0 0 0 0 156476 0 166258 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQMAAEDC(Carbamidomethyl)AK MGYG000002293_00481;MGYG000003697_01443;MGYG000001056_02461;MGYG000003374_01465;MGYG000004629_00380 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG4219@1|root,COG4219@2|Bacteria,4NDWS@976|Bacteroidetes,2FNCU@200643|Bacteroidia,4ANYH@815|Bacteroidaceae 0.4 976|Bacteroidetes 1.0 J 0.6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.6 rpsK 0.6 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 0.6 - 1.0 ko:K02948 0.6 ko03010,map03010 0.6 M00178,M00179 0.6 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.6 - 1.0 - 1.0 - 1.0 Ribosomal_S11 0.6 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00481 0.2 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.6 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 0.6 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1219274 0 0 1043670 0 0 0 0 0 0 0 0 0 0 0 2491772 0 0 0 2009835 1701753 1705330 0 0 0 3139068 0 0 0 0 1561908 0 0 0 0 1518195 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQMAAETAA(Ala->Thr)K MGYG000001315_01363;MGYG000001602_00406;MGYG000003486_01280;MGYG000003687_04935;MGYG000004699_00255;MGYG000003355_02337;MGYG000000164_02739;MGYG000002212_00566 domain d__Bacteria 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,268PI@186813|unclassified Clostridiales 0.5 186801|Clostridia 0.875 J 0.75 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.75 rpsK 0.75 - 0.875 - 1.0 ko:K02948 0.75 ko03010,map03010 0.75 M00178,M00179 0.75 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.75 - 1.0 - 1.0 - 0.75 Ribosomal_S11 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01363 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.75 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 0.75 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1150003 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQMAAETAAK MGYG000001315_01363;MGYG000001602_00406;MGYG000003486_01280;MGYG000003687_04935;MGYG000004699_00255;MGYG000003355_02337;MGYG000000164_02739;MGYG000002212_00566 domain d__Bacteria 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,268PI@186813|unclassified Clostridiales 0.5 186801|Clostridia 0.875 J 0.75 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.75 rpsK 0.75 - 0.875 - 1.0 ko:K02948 0.75 ko03010,map03010 0.75 M00178,M00179 0.75 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.75 - 1.0 - 1.0 - 0.75 Ribosomal_S11 0.75 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01363 0.125 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.75 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 0.75 none 1.0 0 0 0 183416 0 717587 437603 1125690 0 1137170 735518 0 1167045 0 1144601 964473 0 582366 1338548 1451680 0 1187046 647947 706853 0 0 0 852222 0 0 0 0 0 0 1074082 951019 0 0 0 0 0 1061533 0 0 1407926 715072 0 498435 389781 0 664483 0 306710 550927 0 1156520 422287 974461 0 348916 948438 1226930 0 0 0 1057074 0 0 0 0 0 0 828949 901180 0 0 0 0 0 555430 0 0 0 796438 0 299287 0 0 609592 0 0 810194 0 449994 481892 679978 0 421045 477743 320485 0 0 0 249738 0 0 0 0 0 0 514821 0 0 0 0 0 0 490670 0 569452 466978 579223 0 349965 258751 0 478588 0 611171 983170 0 660477 480829 676829 0 1010665 0 843526 0 0 0 1175227 0 0 0 0 0 0 455340 120551 0 0 0 0 0 0 0 0 245718 240178 0 0 0 0 0 0 0 214642 0 302020 0 0 0 312904 259692 0 0 0 0 0 0 0 0 0 0 0 0 561517 0 0 +AAQMAAETATK MGYG000002528_01864;MGYG000003215_00849;MGYG000000142_02038;MGYG000004055_01475;MGYG000000301_00188;MGYG000000171_01879;MGYG000002025_01287;MGYG000003500_00156;MGYG000004735_02050;MGYG000001338_02782;MGYG000004740_00893;MGYG000002286_01563;MGYG000002559_01476;MGYG000000532_01246;MGYG000001141_01291;MGYG000001564_01925;MGYG000000204_02185;MGYG000001637_00006;MGYG000003694_02453;MGYG000003422_00383;MGYG000000356_00499;MGYG000001456.1_01726;MGYG000000216_02331;MGYG000002670_00411;MGYG000000154_01812;MGYG000000139_02422;MGYG000000245_02664;MGYG000000136_02053;MGYG000001186_01087;MGYG000000201_02106;MGYG000002492_00401;MGYG000001493_03358;MGYG000000050_01197;MGYG000000028_01597;MGYG000000153_02068;MGYG000004879_02709 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia 0.5 186801|Clostridia 1.0 J 0.9444444444444444 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.6111111111111112 rpsK 0.6111111111111112 - 1.0 - 1.0 ko:K02948 0.6111111111111112 ko03010,map03010 0.9444444444444444 M00178,M00179 0.9444444444444444 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.9444444444444444 - 1.0 - 1.0 - 0.9444444444444444 Ribosomal_S11 0.6111111111111112 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01864 0.027777777777777776 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.9444444444444444 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 0.6111111111111112 none 1.0 2565808 2014826 2389548 2756310 2986034 2047751 0 2225747 0 2466990 2787534 0 0 0 0 2639415 2135088 3482009 0 2474224 0 2060368 2768065 1492389 0 2066784 1979704 3120132 2141104 0 1957911 2151835 2395874 0 2251344 2028142 2291789 2174041 1479067 2740019 1051216 1706093 1698943 894478 0 1584797 0 1417425 1377634 0 0 0 0 1632828 1230537 4301859 0 1409673 0 1078439 2977740 2036096 0 1211088 1884116 4692428 2329234 0 3136275 2027779 1710761 0 1478905 1649186 1247312 1705346 967723 2141650 1710698 865564 670541 1441108 0 1067529 0 837865 608382 0 0 0 0 1594685 1409148 1571076 0 872471 0 1869893 1690759 1110632 0 1569248 1399316 2414534 1387208 0 684018 1960833 2269222 0 1057127 751729 1133138 1652841 2680277 2374583 1665916 1689645 2092485 1121572 0 2200196 0 1842027 1806241 0 0 0 0 2749199 2042991 2080543 0 2607402 0 547198 534445 0 0 160756 3269869 2043581 2657255 0 3298784 1895828 1485354 0 0 1420782 2879721 2088433 3255992 2842710 1886040 2742014 1996447 2108843 0 3169030 0 2995626 2810635 0 0 0 0 1976496 3354282 1250199 0 2071171 0 2143196 1834115 2763070 0 4281422 3826168 1701501 2887961 0 2018708 2255690 3081686 0 3932402 4470075 0 0 +AAQMAAETTAK MGYG000001511_00066 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Bacillales_E|f__Massilibacteriaceae|g__Massilibacterium|s__Massilibacterium senegalense|m__MGYG000001511 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli,1ZFIU@1386|Bacillus 1.0 91061|Bacilli 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001511_00066 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1316322 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2863875 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2968526 2709500 +AAQMAAQDC(Carbamidomethyl)AK MGYG000002721_02313;MGYG000001599_01826;MGYG000003420_01325;MGYG000001433_02301;MGYG000001345_04724;MGYG000002218_02495;MGYG000000781_00873;MGYG000003498_00774;MGYG000000696_01638;MGYG000002281_02250;MGYG000003164_01271;MGYG000001835_02485;MGYG000004763_00950;MGYG000003681_02077;MGYG000001370_01720;MGYG000001666_01381;MGYG000001378_05002;MGYG000001787_01778;MGYG000000013_02211;MGYG000001306_02685;MGYG000002935_01264;MGYG000000196_04014;MGYG000002561_02200;MGYG000001337_03864;MGYG000002470_01205;MGYG000001313_00049;MGYG000000054_03883;MGYG000001461_00429;MGYG000001789_00105;MGYG000000174_03501;MGYG000002418_00853;MGYG000000673_01669;MGYG000000273_00381;MGYG000000138_02864;MGYG000003693_00218;MGYG000002438_02233;MGYG000001780_04852;MGYG000003202_00871;MGYG000000044_02999;MGYG000000029_02814;MGYG000002560_00261;MGYG000002762_00888;MGYG000002455_03924;MGYG000001346_01494;MGYG000001871_02152;MGYG000000105_02030;MGYG000003233_00179;MGYG000000236_01762;MGYG000002291_02230;MGYG000004797_02000;MGYG000002275_02092;MGYG000002181_02223;MGYG000003701_04719;MGYG000003521_01403;MGYG000004748_03267;MGYG000001659_00171 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0100@1|root,COG0100@2|Bacteria,4NNHA@976|Bacteroidetes,2FRZD@200643|Bacteroidia,22XN9@171551|Porphyromonadaceae 0.5178571428571429 976|Bacteroidetes 1.0 J 0.5178571428571429 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.5178571428571429 rpsK 0.5178571428571429 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 0.5178571428571429 - 1.0 ko:K02948 0.5178571428571429 ko03010,map03010 0.5178571428571429 M00178,M00179 0.5178571428571429 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 0.5178571428571429 - 1.0 - 1.0 - 1.0 Ribosomal_S11 0.5178571428571429 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002721_02313 0.017857142857142856 - - - - 1.0 1.0 1.0 1.0 Ribosome 0.5178571428571429 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 0.5178571428571429 none 1.0 1130244 696104 1504601 1180829 1245185 1074689 1806373 1200075 1205097 1084413 2409909 1536450 1356605 1552707 1544199 1440286 1107624 1127828 2119709 1686410 1393504 1376286 1430579 1333562 1640769 1312181 1075297 1390159 1251538 868182 1103259 913871 1280077 1447644 0 1540421 1234659 1008504 674304 370384 550609 1038770 764406 614004 766754 982425 765442 959445 1299408 1114224 964142 1044080 1027719 1015824 653575 1908734 742063 1085363 1028729 829901 3806366 579968 782458 996062 890139 2694860 745667 895497 574114 828991 837139 859561 0 755886 667723 453896 196411 301599 426390 238523 401591 388931 374375 288381 324481 0 473006 379044 341451 313973 278765 469849 487224 951621 229765 393413 285729 393582 722301 240509 143367 231086 252494 640141 372455 261326 332268 207413 227705 103749 0 381112 269270 295500 939149 846571 819540 665696 1113313 1036581 932377 870960 781664 763158 928890 929500 673023 712618 697682 1128989 765759 889789 929347 897262 585765 934066 281535 672993 861015 992819 808922 877068 887429 855009 1065403 720940 968670 693488 0 613954 632303 1149974 385124 99680 204955 164243 521719 372225 392919 368357 471576 0 482892 553822 363506 0 0 521073 449666 1160589 383884 536334 522111 301646 1084739 378625 353200 669072 0 715943 269701 474880 0 0 0 317416 0 492768 0 359231 +AAQMALK MGYG000001378_03103 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides ovatus|m__MGYG000001378 1.0 COG0702@1|root,COG0702@2|Bacteria,4NHVQ@976|Bacteroidetes,2FPT0@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 GM 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001378_03103 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2287940 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQMDEWFSGK MGYG000002293_00078;MGYG000003697_02025 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the transketolase family 1.0 tkt 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00078 0.5 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 625170 667549 1143606 0 752328 1119208 779339 774545 571080 0 1028104 603120 972054 804858 541138 842409 0 4979567 0 474904 585366 1384152 4216380 1087299 854425 702146 0 2377379 741399 0 704100 847877 1068548 882973 739202 920259 740503 1035359 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQMDEWFSGKAPK MGYG000002293_00078;MGYG000003697_02025 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0021@1|root,COG0021@2|Bacteria,4P14U@976|Bacteroidetes,2FN0P@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the transketolase family 1.0 tkt 1.0 - 1.0 2.2.1.1 1.0 ko:K00615 1.0 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 1.0 M00004,M00007,M00165,M00167 1.0 R01067,R01641,R01830,R06590 1.0 RC00032,RC00226,RC00571,RC01560 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Transket_pyr,Transketolase_C,Transketolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00078 0.5 transketolase. glycoaldehyde transferase. Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.-!-The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor. D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D- ribose 5-phosphate + D-xylulose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Carbon fixation in photosynthetic organisms|Biosynthesis of ansamycins|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids 1.0 K00615:E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1] 1.0 none 1.0 0 0 303248 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 607210 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 535835 0 0 0 261621 392189 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1697140 0 916016 1463788 0 0 0 0 1271970 0 0 0 0 1253720 0 3828035 0 0 0 1586045 6690145 1115868 0 0 0 3252328 0 0 983047 914788 1379390 878624 0 0 0 1328786 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQMMVYR MGYG000000255_01556;MGYG000000205_02133 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__CAG-81 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,21YI4@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000255_01556 0.5 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 1821722 1471590 964787 1219691 1520823 1175095 1270037 2230314 1199953 1773312 799084 1514818 1239825 1844144 1086278 913312 1707221 0 1139055 1580728 1631896 1097563 0 865872 1409876 1176136 1482320 0 1617247 1146252 751102 1016057 899602 2114495 1745711 1173246 1193740 928232 9233281 4019175 3850881 9182695 4653383 3395421 7721904 6589189 4832787 8782110 3724250 5559993 6325017 6125121 6145353 3996749 6210416 0 4735968 6156440 6252037 3146747 0 3720803 6656714 5587761 7059989 0 7379580 4851558 3641418 3493734 5159258 9555270 6139784 7851110 5387136 3895614 1523231 1036576 815195 1084753 604215 744629 1207785 1719919 1252232 1567118 694094 707947 1003847 1383950 1337745 961955 1216222 0 1511579 1490850 1100565 1222554 0 920713 1825472 1520778 1678089 0 1382077 697946 640771 1295166 1129432 2475740 980228 1178176 1139075 1017188 703399 2214189 365477 391458 291137 2713610 404710 558839 368646 444261 145711 314989 366191 356423 396141 360901 214291 0 172375 552923 570973 460782 0 1653191 329891 227512 515586 0 237460 158905 1941037 2327882 2804203 280013 394645 335703 412159 194213 407193 909052 701974 1161446 738541 792188 1670874 1323264 876068 1023892 501759 1260618 487276 1014646 908985 1099497 618727 0 706057 731977 543334 1422303 0 1050514 888552 282476 282735 0 1161898 491896 1063396 690667 911018 1988637 800944 646722 562862 939320 +AAQNDPAVQEAVK MGYG000001300_02007 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3WGDW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate 1.0 glmM 1.0 - 1.0 5.4.2.10 1.0 ko:K03431 1.0 ko00520,ko01100,ko01130,map00520,map01100,map01130 1.0 - 1.0 R02060 1.0 RC00408 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02007 1.0 phosphoglucosamine mutase. - The enzyme is involved in the pathway for bacterial cell-wall peptidoglycan and lipopolysaccharide biosyntheses, being an essential step in the pathway for UDP-N-acetylglucosamine biosynthesis.-!-The enzyme from Escherichia coli is activated by phosphorylation and can be autophosphorylated in vitro by alpha-D-glucosamine 1,6- bisphosphate, which is an intermediate in the reaction, alpha-D- glucose 1,6-bisphosphate or ATP.-!-It can also catalyze the interconversion of alpha-D-glucose 1-phosphate and alpha-D-glucose 6-phosphate, although at a much lower rate. alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. 1.0 1.0 1.0 1.0 Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K03431:glmM; phosphoglucosamine mutase [EC:5.4.2.10] 1.0 none 1.0 0 922600 975583 695198 0 574129 270323 0 0 0 322667 0 989507 0 0 0 556205 0 0 831281 0 692909 0 550886 520061 0 0 0 0 0 0 0 1246250 0 0 0 0 1032219 0 1010015 981098 1152244 0 831800 1180608 0 0 0 502136 0 618190 0 0 0 1140858 0 0 864846 0 551908 0 706526 1142738 0 0 0 0 0 0 0 1216040 0 0 0 0 867654 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 914699 1423604 941494 0 1106388 1530413 0 0 0 893166 0 910485 0 0 0 992736 0 0 1003154 0 1454747 0 968361 945245 0 0 0 0 0 0 0 1138142 0 0 0 0 1398457 0 0 0 135707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 166852 0 0 0 0 0 +AAQNIIPSSTGAAK MGYG000001692_02867 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Aeromonadaceae|g__Aeromonas|s__Aeromonas dhakensis|m__MGYG000001692 1.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,1Y3YS@135624|Aeromonadales 1.0 135624|Aeromonadales 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001692_02867 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5273777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQNVSGPLVSR MGYG000002494_03842 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0784@1|root,COG0835@1|root,COG0784@2|Bacteria,COG0835@2|Bacteria,1N81M@1224|Proteobacteria,1RPS1@1236|Gammaproteobacteria,3WXW5@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 T 1.0 Two component signalling adaptor domain 1.0 cheV 1.0 - 1.0 - 1.0 ko:K03415 1.0 ko02020,ko02030,map02020,map02030 1.0 M00506 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02022,ko02035 1.0 - 1.0 - 1.0 - 1.0 CheW,Response_reg 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03842 1.0 - - - - 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03415:cheV; two-component system, chemotaxis family, chemotaxis protein CheV 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1404534 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1730217 0 1269527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQPIVDSVADIKK MGYG000000362_01314 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-115|s__CAG-115 sp003531585|m__MGYG000000362 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000362_01314 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1955491 0 0 0 0 2565700 0 0 0 0 2391636 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 103536 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7436200 0 0 0 0 6657158 0 0 0 0 7639864 0 0 0 0 0 0 0 0 0 0 +AAQPLMTILHPEK MGYG000000042_02028 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola sp900066445|m__MGYG000000042 1.0 COG3537@1|root,COG3537@2|Bacteria,4NDYB@976|Bacteroidetes,2FMQ9@200643|Bacteroidia,4AK7H@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 Alpha-1,2-mannosidase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_125,Glyco_hydro_92 1.0 3.2.1.-|3.2.1.114 1.0 GH92 1.0 GH92 1.0 GH92 1.0 MGYG000000042_02028 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94590 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 483952 0 0 0 0 803116 0 0 0 0 511777 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 89697 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 173778 0 0 0 0 203860 0 0 0 0 224423 0 0 0 0 0 0 0 0 0 0 +AAQQAAKPEPQEAR MGYG000000262_00560 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0305@1|root,COG0305@2|Bacteria,1W6Y2@1239|Firmicutes,25M5M@186801|Clostridia,25ZAD@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 L 1.0 Participates in initiation and elongation during chromosome replication 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DnaB_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_00560 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 96553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 970851 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 164698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQQEVTK MGYG000002517_01169 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia 1.0 186801|Clostridia 1.0 S 1.0 associated with various cellular activities 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 AAA,AAA_5 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01169 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1770446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1106546 0 +AAQSAAETAAK MGYG000001255_02107;MGYG000000258_00308;MGYG000002926_00510;MGYG000001673_01419;MGYG000001733_00006;MGYG000001300_02188;MGYG000004487_00995;MGYG000003899_00640;MGYG000000022_02014;MGYG000003166_00785;MGYG000002619_02360;MGYG000004475_01165;MGYG000000392_01434;MGYG000002143_01912;MGYG000004525_00990;MGYG000002272_00477;MGYG000002720_00255;MGYG000002794_00566;MGYG000002984_00006;MGYG000003494_00371;MGYG000000195_02107;MGYG000002156_01377;MGYG000002545_01114;MGYG000003937_00240;MGYG000002224_01634 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3WIYT@541000|Ruminococcaceae 0.56 186801|Clostridia 0.92 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 0.92 rpsK 0.92 - 0.92 - 0.92 ko:K02948 0.92 ko03010,map03010 0.92 M00178,M00179 0.92 - 0.92 - 0.92 br01610,ko00000,ko00001,ko00002,ko03011 0.92 - 1.0 - 1.0 - 1.0 Ribosomal_S11 0.92 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001255_02107 0.04 - - - - 0.92 0.92 0.92 0.92 Ribosome 0.92 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 0.92 none 1.0 1410632 944333 2151332 2439288 1042322 1468068 1348160 1278577 2073665 1936116 0 1358248 1789592 1799213 0 1820975 2036160 5532901 2725844 2911264 1247009 1612537 3542350 1361417 2119054 2114919 1756339 3437852 1190915 1379732 1709844 1429154 1977814 2618401 0 1819269 1747976 1760419 1068634 584542 747520 1682424 652572 629358 1576241 678698 900465 278760 0 1013361 790717 1372293 0 984612 1037863 2654766 958186 1109699 437660 935566 5129418 1015731 963233 1070372 1284904 5465265 415104 876270 1424863 689141 674815 986893 0 924874 939470 553065 391577 663647 566187 718398 526487 564816 379731 674296 821263 502800 0 439390 612116 662222 0 484002 486798 345620 515868 557539 684916 442216 1108295 610666 546073 541935 629249 1887115 673360 343867 514387 391001 486802 662480 0 752427 721311 898856 2147808 1942029 2923409 2306588 2205150 2491737 2420887 1628695 1902703 1876838 0 2326452 1750040 1780465 0 2576075 2083280 6199485 2242825 2546108 824164 3138202 1745392 2934815 2066779 3562941 2501743 7606404 1371903 1905512 3088286 1667729 2776552 1630043 0 744423 1767376 2994539 143900 187101 289243 122928 170929 246824 438571 0 335649 0 0 206060 235346 0 0 131316 441543 1099568 0 204653 113288 170026 1144267 214488 381713 421145 0 302472 207206 351761 269911 0 0 493549 0 236020 316574 238762 +AAQSIAVAR MGYG000002953_03277;MGYG000002670_01511;MGYG000002727_00924;MGYG000002057_01748;MGYG000003215_01534;MGYG000004482_00909;MGYG000002974_01391;MGYG000002720_01849;MGYG000001616_02334;MGYG000001617_02042;MGYG000001637_02269;MGYG000003694_00877;MGYG000000153_01463;MGYG000001502_00825;MGYG000003589_00853;MGYG000002492_00657;MGYG000004276_00829;MGYG000002707_01243;MGYG000000489_01023;MGYG000002445_02272;MGYG000002926_00108;MGYG000000280_01473;MGYG000002143_01933;MGYG000000377_01679;MGYG000004487_00561;MGYG000004784_00845;MGYG000000389_02151;MGYG000004271_00231;MGYG000001683_01598;MGYG000000245_02019;MGYG000000271_02104;MGYG000001186_01723;MGYG000004475_01257 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.3939393939393939 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.5151515151515151 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002953_03277 0.030303030303030304 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 2032219 1612500 1413707 0 2042516 2008429 2130035 1695060 1803800 1557675 1617550 1721372 0 2174980 2992291 1817295 1614438 5313921 0 2237730 0 1995154 5914570 2244041 2291868 2000788 0 4000217 0 0 1974864 2516213 1676224 2642096 2095931 1955583 2171852 1951756 117213 0 0 0 0 113204 0 0 0 157915 0 77246 0 0 243452 0 166702 1143204 0 0 0 0 1757700 0 0 0 0 1319423 0 0 0 0 157792 237055 249053 0 0 0 14016177 7962418 31053892 0 10394872 4861346 10164478 13327893 15087475 8361289 9181063 8743922 0 12412850 13169796 6978567 5787434 5888304 0 16021489 0 4622361 5517065 5128636 14200968 9893028 0 5896970 0 0 7618525 4856262 23098517 14865474 6769201 12620461 14575450 22489584 1307070 3344343 3797974 0 2938941 3717689 2066975 1871661 2229380 3394719 2539307 2137101 0 2027606 1695850 3033197 2374651 3936770 0 2352576 0 3708744 1738297 5435195 986293 973261 0 8451091 0 0 5263212 2106533 3989498 959995 1870976 1054045 1447617 6514429 755013 230469 440020 0 557616 472097 334909 514496 420079 709736 310093 1891614 0 603216 256748 311943 636800 3647553 0 667001 0 407257 3065336 500928 481940 688951 0 2293746 0 0 558183 569197 303674 690513 398086 849056 532378 341372 +AAQSIAVAR(Arg->Gln)DLK MGYG000000489_01023 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Agathobacter|s__Agathobacter sp900548765|m__MGYG000000489 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000489_01023 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1503996 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQSIGEPGTQLTLR MGYG000001666_00329;MGYG000001789_00145;MGYG000004797_04274;MGYG000000196_03983;MGYG000001431_01172;MGYG000003681_02045;MGYG000000243_01979;MGYG000001346_01525;MGYG000002438_02330;MGYG000002478_00805;MGYG000004757_00585;MGYG000004885_00605 domain d__Bacteria 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 0.5833333333333334 976|Bacteroidetes 0.9166666666666666 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 1.0 rpoC 1.0 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 0.9166666666666666 2.7.7.6 1.0 ko:K03046 0.9166666666666666 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 0.9166666666666666 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000001666_00329 0.08333333333333333 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 0.9166666666666666 none 1.0 594479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 794417 0 0 0 0 0 0 0 0 0 0 733852 0 860044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1190321 0 0 0 0 0 0 0 0 0 0 934838 0 1173250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1149289 0 0 0 0 0 0 0 0 0 0 1101279 0 388491 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 513953 0 0 0 0 0 0 0 0 0 0 596082 0 723828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 538018 0 0 0 0 0 0 0 0 0 0 458324 0 +AAQSLAVAQDLK MGYG000001714_01774 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Coprococcus_A|s__Coprococcus_A catus|m__MGYG000001714 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001714_01774 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1242749 0 0 0 0 0 0 0 0 0 0 0 1335588 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQSLAVAR MGYG000000489_01023;MGYG000002727_00924;MGYG000000245_02019;MGYG000002926_00108;MGYG000001689_03867;MGYG000003589_00853;MGYG000002492_00657 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia 0.42857142857142855 186801|Clostridia 1.0 I 1.0 Thiolase, C-terminal domain 0.5714285714285714 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000489_01023 0.14285714285714285 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 397828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17110773 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQSLAVGR MGYG000000262_02231 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerobutyricum|s__Anaerobutyricum hallii|m__MGYG000000262 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 1.0 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000262_02231 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 1140199 120207 169907 1305288 0 196005 532231 292015 0 98495 0 191437 181564 0 272210 1129156 592980 0 249090 533035 931867 147591 0 1076113 0 1066037 0 0 152565 1106948 854417 929257 542031 242886 156778 704910 1083449 578219 1728604 1786101 297064 195848 0 0 1180516 1506799 0 1583356 800295 1125087 688061 0 1059208 994338 1316333 0 84377 114932 1373414 2754867 0 1984157 0 1002580 0 0 1865682 82125 658505 1416071 1170970 1588082 1544029 1489394 1194631 837957 16385881 13776458 4454818 18591290 0 7899655 3728369 13041083 0 11690465 3720563 6221767 10064239 0 16814088 8036640 6598185 0 16005431 19206828 12924718 10959143 0 3984414 0 12106244 0 0 1707522 11981055 2190249 8517618 7554942 21036522 15690008 5884340 12232534 3224218 2722144 2021173 649832 2369923 0 1128785 1859496 523456 0 1800842 1222629 630187 810855 0 3320698 1962110 2145980 0 2179051 2985577 800768 1158732 0 1529535 0 372159 0 0 1587833 2195859 1638455 1416352 1186171 1397821 676914 2155410 2520692 1077410 1865903 1946888 3269491 0 0 2705510 1800436 1587400 0 3114488 2802465 2356724 835861 0 1800971 2228939 3407114 0 2098945 1278282 2512619 1837073 0 2119394 0 3291894 0 0 565420 1711883 2814637 440439 2326822 2164023 1280128 4473857 3073285 2864416 +AAQSLGVIHELVEEHGIDR MGYG000000223_02388 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,3VP0M@526524|Erysipelotrichia 1.0 526524|Erysipelotrichia 1.0 I 1.0 Thiolase, C-terminal domain 1.0 - 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_02388 1.0 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 471801 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQSVAVAR MGYG000000204_00804;MGYG000002528_02664;MGYG000000028_00940;MGYG000001500_00694;MGYG000002517_00540 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,25VH5@186806|Eubacteriaceae 0.6 186801|Clostridia 1.0 I 1.0 Belongs to the thiolase family 0.8 thlA 1.0 - 1.0 2.3.1.9 1.0 ko:K00626 1.0 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 1.0 M00088,M00095,M00373,M00374,M00375 1.0 R00238,R01177 1.0 RC00004,RC00326 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000204_00804 0.2 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 1.0 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 1.0 none 1.0 765142 400581 522578 647632 1459810 393725 300728 613459 709582 973259 1216284 682522 897195 1132099 2216879 1410317 739748 822177 1891209 1242500 489646 1050346 332476 260004 1274753 862522 706706 211307 211089 442116 0 1047199 734877 632124 1034242 495080 658975 568074 217893 3435208 270182 195119 534856 265006 222271 278334 304602 0 334516 0 823834 0 0 83541 126651 320659 197942 331321 158634 0 110962 289155 376051 131358 324955 0 787405 451992 0 1003774 453344 485934 0 602351 263422 330096 4835450 16510914 5764147 3084168 1310985 8594960 4408071 9682659 5909793 8453572 3871305 6177886 5634108 6134161 10089428 6298234 5711279 679325 15743626 11813397 5986567 15567155 1557207 5206407 11678665 9351556 6225384 2039669 11498503 9484967 0 12866136 7653031 18701078 5988966 8955755 6391591 4729626 15447188 8436571 9300498 19101488 14143040 7072790 8716501 14400009 18926664 15531878 10296689 6448842 3981026 21729255 22063768 8986113 22127000 1038436 18376238 23760605 4113159 5108827 0 10319843 14655832 9965113 15402753 3068946 15700731 23258543 0 6127195 6322251 4924963 16541026 9550568 18017210 13582249 1222223 1482407 1829043 1333650 364514 1330727 1227028 470637 1285887 1084967 2123608 6558154 1504260 1015691 1770433 675749 1419324 173978 407604 751962 691045 855220 0 1477063 1675860 1258829 1665789 315079 403169 634620 0 2486554 4080104 480508 764397 1594806 1622231 2226847 +AAQSVAVGK MGYG000000205_02136;MGYG000003486_02525;MGYG000000217_01337;MGYG000000255_01552;MGYG000000325_01142 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,4BWBU@830|Butyrivibrio 0.4 186801|Clostridia 1.0 I 0.8 Thiolase, C-terminal domain 0.8 thlA 0.8 - 1.0 2.3.1.9 0.8 ko:K00626 0.8 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 0.8 M00088,M00095,M00373,M00374,M00375 0.8 R00238,R01177 0.8 RC00004,RC00326 0.8 ko00000,ko00001,ko00002,ko01000,ko04147 0.8 - 1.0 - 1.0 - 1.0 Thiolase_C,Thiolase_N 0.8 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02136 0.2 acetyl-CoA C-acetyltransferase. acetoacetyl-CoA thiolase. The enzyme, found in both eukaryotes and prokaryotes, catalyzes the Claisen condensation of an acetyl-CoA and an acyl-CoA (often another acetyl-CoA), leading to the formation of an acyl-CoA that is longer by two carbon atoms.-!-The reaction starts with the acylation of a nucleophilic cysteine at the active site, usually by acetyl-CoA but potentially by a different acyl-CoA, with concomitant release of CoA.-!-In the second step the acyl group is transferred to an acetyl-CoA molecule. cf. EC 2.3.1.16. 2 acetyl-CoA = acetoacetyl-CoA + CoA. 0.8 0.8 0.8 0.8 Fatty acid degradation|Valine, leucine and isoleucine degradation|Lysine degradation|Benzoate degradation|Tryptophan metabolism|Pyruvate metabolism|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Terpenoid backbone biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism|Two-component system 0.8 K00626:ACAT, atoB; acetyl-CoA C-acetyltransferase [EC:2.3.1.9] 0.8 none 1.0 0 0 0 0 0 415103 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 555972 0 420537 596588 0 0 0 0 0 0 0 0 434146 0 0 0 0 0 0 0 0 0 1085466 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 786163 0 1050021 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 593922 0 0 1534594 0 0 0 0 0 0 0 0 2745162 0 0 0 0 0 0 0 0 0 1086143 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1529234 0 2354323 469298 0 0 0 0 0 0 0 0 317923 0 0 0 0 0 0 0 0 0 168366 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153688 0 468417 367745 0 0 0 0 0 0 0 0 405919 0 0 0 0 +AAQT(Thr->Ser)AAETAAK MGYG000002835_01005 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Fusicatenibacter|s__Fusicatenibacter sp900543115|m__MGYG000002835 1.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,268PI@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome 1.0 rpsK 1.0 - 1.0 - 1.0 ko:K02948 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S11 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002835_01005 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02948:RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 882146 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 477529 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQTE(Glu->Phe)SFGYNTDEIVSSDIVGMR MGYG000002528_00367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00367 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 422669 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 342231 0 192164 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 240558 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 161309 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQTESFGYN(Deamidated)TDEIVSSDIVGM(Oxidation)R MGYG000002528_00367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00367 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 788787 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1055150 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQTESFGYNTD(Cation_Na)EIVSSDIVGMR MGYG000002528_00367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00367 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 186294 0 0 0 398483 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 459981 0 0 0 0 0 0 0 0 0 257936 0 0 0 0 0 0 0 1318936 0 0 0 691067 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 479150 0 1119474 0 0 0 0 0 0 0 718635 0 0 0 0 0 0 0 1446885 0 0 0 891323 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1828563 0 688358 0 0 0 0 0 0 0 2026938 0 0 0 0 0 0 0 754231 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQTESFGYNTDE(Cation_Na)IVSSDIVGMR MGYG000002528_00367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00367 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1333442 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQTESFGYNTDEIVSSDIVGM(Oxidation)R MGYG000002528_00367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00367 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 439497 0 0 0 0 0 505459 0 0 0 0 0 0 231194 0 0 0 0 0 0 0 0 0 0 785633 0 0 0 427363 0 0 0 0 0 0 0 0 0 369686 0 0 0 0 0 264833 0 746563 0 0 0 0 352280 0 0 358796 0 0 0 0 0 0 0 2949297 0 0 0 1116501 0 0 0 0 0 0 0 0 0 601983 0 0 845687 0 0 2310322 0 1181007 0 0 0 0 1688857 0 0 2200905 0 660331 0 0 0 0 0 512660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 220217 0 0 0 0 1168468 0 0 364606 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 132293 0 0 0 0 +AAQTESFGYNTDEIVSSDIVGMR MGYG000002528_00367 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus|m__MGYG000002528 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,27ICJ@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_00367 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 822034 493852 0 646160 692037 0 172224 0 407005 636802 584145 588030 547124 345915 447032 290348 624690 246548 289724 0 1008438 506279 503917 329689 302152 451001 587612 1278574 344283 644890 0 349801 541011 428921 0 325269 470760 328179 4358352 597550 0 1173652 2178743 405192 497109 0 0 333515 230815 466531 414030 472633 559183 559341 2429061 321895 593618 357200 1434154 1161641 3843184 0 503596 610523 1556494 1197073 0 1812015 2269701 506657 510500 442807 0 338940 666420 1427501 7985931 3942797 0 1189387 3541209 1821590 1899002 0 1589630 1931258 1991204 1773213 1150202 1423732 2069185 1827228 224724 2643491 1219974 1523158 7105346 1062308 6020535 1866199 4967184 1918701 1131707 5671203 1373055 1290862 15284681 3696592 2239718 3185140 0 2570983 4460768 695806 3609266 2211919 0 4219346 1274858 1977341 999894 0 192673 1648175 929349 4323153 1408257 359574 2385869 1544384 230337 464220 2183493 0 196190 0 9038751 1043044 708004 983140 0 19153534 356789 8909423 6599473 5435504 245510 250657 0 358714 5466316 0 307438 179110 0 0 210706 0 177241 0 227847 0 212219 0 0 0 156236 273886 0 0 198876 0 0 3638464 567738 0 2429353 0 394787 0 335648 402504 0 345805 0 0 0 0 284742 +AAQTGEIGDGR MGYG000000196_04260;MGYG000001313_01813 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0347@1|root,COG0347@2|Bacteria,4NQG9@976|Bacteroidetes,2FSGK@200643|Bacteroidia,4AQX6@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 K 1.0 Belongs to the P(II) protein family 1.0 glnB 1.0 - 1.0 - 1.0 ko:K04751 1.0 ko02020,map02020 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001 1.0 - 1.0 - 1.0 - 1.0 P-II 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000196_04260 0.5 - - - - 1.0 1.0 1.0 1.0 Two-component system 1.0 K04751:glnB; nitrogen regulatory protein P-II 1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 969075 0 0 0 0 858696 0 0 0 0 494149 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1269414 0 0 0 0 593957 0 0 0 0 909527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263700 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQTIEVATR MGYG000000022_02855 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C|m__MGYG000000022 1.0 COG2211@1|root,COG2211@2|Bacteria,1TRYR@1239|Firmicutes,24FE0@186801|Clostridia,3WN0N@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 MFS/sugar transport protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MFS_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_02855 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1801121 0 0 0 0 1909981 0 0 0 0 1841172 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 728111 0 2380522 0 0 0 0 0 0 0 0 0 2651493 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 843024 0 0 0 0 601712 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 278588 0 1378921 0 0 0 0 2139482 0 0 0 0 2185252 0 0 0 0 0 0 0 0 0 0 +AAQVAMDVTTK MGYG000000164_00686 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter_A|s__Mediterraneibacter_A butyricigenes|m__MGYG000000164 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 acyl-CoA dehydrogenase 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000164_00686 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 1014435 803240 0 0 0 975500 1356694 1688632 1525443 0 0 0 0 1100011 1662815 0 0 0 1429063 2236244 1051342 853447 0 607037 1803556 1261581 0 0 0 1130081 0 0 0 0 0 0 1027467 0 385879 0 0 0 0 0 118865 218490 610313 0 0 0 0 0 0 0 0 0 0 286208 468215 0 0 0 228514 344217 0 0 0 625238 0 0 0 0 0 0 348629 0 0 0 0 0 0 0 366909 0 0 0 0 0 0 0 300412 0 0 0 132107 0 287696 0 0 0 0 0 0 0 0 268161 0 0 0 0 0 0 0 0 0 0 0 0 0 260396 328979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 581753 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447617 0 0 0 0 0 0 0 0 +AAQVEEIAK MGYG000003921_01311;MGYG000001300_02638;MGYG000003166_01200 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae 1.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3WICR@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors 1.0 rplK 1.0 - 1.0 - 1.0 ko:K02867 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L11,Ribosomal_L11_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003921_01311 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02867:RP-L11, MRPL11, rplK; large subunit ribosomal protein L11 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3220972 0 0 0 0 0 0 0 0 0 2933553 0 0 0 0 0 2262362 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 733082 1872635 0 0 0 772336 0 0 0 0 570918 0 0 0 0 0 1789065 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1910705 5342279 0 0 0 1977485 0 0 0 0 1920282 0 0 0 0 0 578793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2839663 3157465 0 0 0 1204036 0 0 0 0 2364617 0 0 0 0 0 1579532 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1189040 0 0 0 0 1094802 0 0 0 0 1124862 0 0 0 0 0 0 0 0 0 0 +AAQVSYNYPAETDEHSYGIDVQNANKK MGYG000004642_00725 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG1804@1|root,COG1804@2|Bacteria,1TP54@1239|Firmicutes,24AFB@186801|Clostridia,36FMV@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 PFAM L-carnitine dehydratase bile acid-inducible protein F 1.0 hadA 1.0 - 1.0 2.8.3.24 1.0 ko:K20882 1.0 - 1.0 - 1.0 R11462 1.0 RC00014,RC00137 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 CoA_transf_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004642_00725 1.0 (R)-2-hydroxy-4-methylpentanoate CoA-transferase. - The enzyme, characterized from the bacterium Peptoclostridium difficile, participates in an L-leucine fermentation pathway.-!-The reaction proceeds via formation of a covalent anhydride intermediate between a conserved aspartate residue and the acyl group of the CoA thioester substrate. (R)-2-hydroxy-4-methylpentanoate + 4-methylpentanoyl-CoA = (R)-2-hydroxy- 4-methylpentanoyl-CoA + 4-methylpentanoate. 1.0 1.0 1.0 1.0 - 1.0 K20882:hadA; (R)-2-hydroxy-4-methylpentanoate CoA-transferase [EC:2.8.3.24] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 908494 0 811018 0 0 1088980 1200301 869630 977847 1069221 0 0 0 0 1262681 0 1145541 0 803829 0 0 1058509 0 1360104 951613 1206677 1150246 0 1245285 0 0 0 860442 1249386 0 1130211 856160 645562 +AAQVTQAHQSLTLDELYQM(Oxidation)MR MGYG000002494_03340 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1461@1|root,COG1461@2|Bacteria,1MXIB@1224|Proteobacteria,1RPJ7@1236|Gammaproteobacteria,3WY50@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Dak2 1.0 dhaL 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 2.7.1.121 1.0 ko:K05879 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECUMN_1333.ECUMN_1495 1.0 Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03340 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways 1.0 K05879:dhaL; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaL [EC:2.7.1.121] 1.0 none 1.0 0 0 0 0 0 0 0 0 383993 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 993036 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQVTQAHQSLTLDELYQMMR MGYG000002494_03340 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG1461@1|root,COG1461@2|Bacteria,1MXIB@1224|Proteobacteria,1RPJ7@1236|Gammaproteobacteria,3WY50@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 S 1.0 Dak2 1.0 dhaL 1.0 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.0 2.7.1.121 1.0 ko:K05879 1.0 ko00561,ko01100,map00561,map01100 1.0 - 1.0 R01012 1.0 RC00015,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 iECUMN_1333.ECUMN_1495 1.0 Dak2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03340 1.0 phosphoenolpyruvate--glycerone phosphotransferase. - - dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate. 1.0 1.0 1.0 1.0 Glycerolipid metabolism|Metabolic pathways 1.0 K05879:dhaL; phosphoenolpyruvate---glycerone phosphotransferase subunit DhaL [EC:2.7.1.121] 1.0 none 1.0 0 0 0 0 0 188163 0 0 0 0 0 0 0 0 255956 0 0 0 0 0 0 321150 0 460213 0 0 0 0 0 0 0 0 0 237055 0 0 0 0 0 0 0 0 0 38618208 0 0 0 0 0 0 0 0 40348475 0 0 0 0 0 0 53533934 0 79106129 0 0 0 0 0 0 0 0 0 14055986 0 0 0 0 0 0 0 0 0 264625 0 0 0 0 0 0 0 0 433988 0 0 0 0 0 0 426350 0 4618766 0 0 0 0 0 0 0 0 0 862657 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 561295 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 173988 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5967308 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQWQNFHK MGYG000001300_01291 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000001300_01291 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 106320 0 164920 0 0 0 0 75787 0 0 0 0 0 0 0 0 169952 0 0 0 287756 0 0 0 0 307094 0 0 0 0 171592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 178529 0 0 87008 54688 0 0 150376 0 0 0 0 0 0 0 0 64591 0 0 0 0 102379 0 0 0 0 0 0 0 0 73565 0 0 0 0 0 0 0 1210687 0 948105 1007593 1616620 0 0 956795 0 0 0 0 0 0 0 1441362 1757019 0 0 1036095 378372 1992894 0 0 0 2111284 0 0 1706851 0 1063450 0 0 0 0 1772903 0 0 534020 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQWTGGGIIFAPTPR MGYG000000002_00881 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A faecis|m__MGYG000000002 1.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia 1.0 186801|Clostridia 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 - 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000002_00881 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQYDGLEIMDR MGYG000002552_00779;MGYG000000187_01833;MGYG000000078_00956;MGYG000004317_00105;MGYG000000562_00476 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Lachnospira 1.0 COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,25UY8@186806|Eubacteriaceae 1.0 186801|Clostridia 1.0 G 1.0 COG0524 Sugar kinases, ribokinase family 1.0 - 1.0 - 1.0 2.7.1.45 1.0 ko:K00874 1.0 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 1.0 M00061,M00308,M00631 1.0 R01541 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002552_00779 0.2 2-dehydro-3-deoxygluconokinase. KDG kinase. The enzyme shows no activity with 2-dehydro-3-deoxy-D-galactonate. cf. EC 2.7.1.178. 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D- gluconate + ADP + H(+). 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00874:kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45] 1.0 none 1.0 1454764 1913722 1708187 2509436 1800435 2260589 1425161 1994955 1890247 2372062 1955713 2239923 1504279 1864742 1941963 0 0 5838094 1826052 1634135 1459186 1634156 5393156 2307262 2155103 1693004 1746796 5583137 2093888 1931620 1992031 2129405 1528987 1931219 1776924 1641498 1728429 1743929 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1110941 0 0 0 0 1190135 0 0 0 0 1130278 0 0 0 0 0 0 0 0 0 0 803659 348611 498499 551988 680210 591079 475948 558455 529901 385376 583741 742161 618813 745540 542094 0 0 2967241 416002 435096 419471 429030 2885097 617203 334820 377167 770374 3169534 796826 778503 707513 394980 562413 698902 525377 454871 514261 709931 743084 883286 417532 814142 1043248 517020 772256 566417 770263 762555 767048 516643 1057426 754065 297662 0 0 2260983 436296 495252 0 1837522 1385441 2197793 252466 373205 838572 2576777 1307696 641705 709717 287734 388654 380989 624121 582362 555962 412918 0 0 291026 0 0 0 407668 287598 589224 984198 362492 294496 508944 297166 0 0 0 2908085 1294798 0 583570 0 2918661 270022 807982 726206 0 3159319 814171 0 0 793601 566874 1340586 871027 320423 1160617 0 +AAQYDTLR MGYG000000074_02643 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Rikenellaceae|g__Alistipes|s__Alistipes onderdonkii|m__MGYG000000074 1.0 COG0059@1|root,COG0059@2|Bacteria,4NFYV@976|Bacteroidetes,2FN0U@200643|Bacteroidia,22US1@171550|Rikenellaceae 1.0 976|Bacteroidetes 1.0 EH 1.0 Acetohydroxy acid isomeroreductase, catalytic domain 1.0 ilvC 1.0 - 1.0 1.1.1.86 1.0 ko:K00053 1.0 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 1.0 M00019,M00570 1.0 R03051,R04439,R04440,R05068,R05069,R05071 1.0 RC00726,RC00836,RC00837,RC01726 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 IlvC,IlvN 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000074_02643 1.0 ketol-acid reductoisomerase (NADP(+)). dihydroxyisovalerate dehydrogenase (isomerizing). The enzyme, found in many bacteria and archaea, is specific for NADPH (cf. EC 1.1.1.382 and EC 1.1.1.383).-!-Formerly EC 1.1.1.89. (1) (2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH. (2) (2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2- hydroxy-3-oxobutanoate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine biosynthesis|Pantothenate and CoA biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00053:ilvC; ketol-acid reductoisomerase [EC:1.1.1.86] 1.0 none 1.0 336531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 456804 0 0 0 0 0 0 0 0 0 0 484756 0 239240 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308462 0 0 0 0 0 0 0 0 0 0 319765 0 586262 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502387 0 0 0 0 0 0 0 0 0 0 579912 0 386064 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1213156 0 0 0 0 0 0 0 0 0 0 947967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQYDVAEAISLVK MGYG000000271_03296 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_03296 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQYDVAEAISLVKK MGYG000000271_03296 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia 1.0 186801|Clostridia 1.0 J 1.0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release 1.0 rplA 1.0 - 1.0 - 1.0 ko:K02863 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000271_03296 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02863:RP-L1, MRPL1, rplA; large subunit ribosomal protein L1 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQYINAIDKNR MGYG000002293_00752 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0446@1|root,COG0446@2|Bacteria,4P1DZ@976|Bacteroidetes,2G0CQ@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Pfam:SusD 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00752 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 102890 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2607249 0 0 0 0 4119502 0 0 0 0 1476892 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQYLVYAAAC(Carbamidomethyl)KK MGYG000001356_00009 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Lawsonibacter|s__Lawsonibacter sp000177015|m__MGYG000001356 1.0 COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,3WI1F@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 bcd 1.0 - 1.0 1.3.8.1 1.0 ko:K00248 1.0 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 1.0 - 1.0 R01175,R01178,R02661,R03172,R04751 1.0 RC00052,RC00068,RC00076,RC00120,RC00148 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,ETF,ETF_alpha 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001356_00009 1.0 short-chain acyl-CoA dehydrogenase. unsaturated acyl-CoA reductase. One of several enzymes that catalyze the first step in fatty acids beta-oxidation.-!-The enzyme catalyzes the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms.-!-The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms.-!-The highest activity was reported with either butanoyl-CoA or pentanoyl-CoA.-!-The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA. cf. EC 1.3.8.7, EC 1.3.8.8 and EC 1.3.8.9.-!-Formerly EC 1.3.2.1 and EC 1.3.99.2. a short-chain 2,3-saturated fatty acyl-CoA + H(+) + oxidized [electron- transfer flavoprotein] = a short-chain (2E)-enoyl-CoA + reduced [electron-transfer flavoprotein]. 1.0 1.0 1.0 1.0 Fatty acid degradation|Valine, leucine and isoleucine degradation|Butanoate metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Fatty acid metabolism 1.0 K00248:ACADS, bcd; butyryl-CoA dehydrogenase [EC:1.3.8.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 223432 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1997165 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2571513 0 0 0 0 0 0 0 0 0 +AAQYPGIEVVPLQVK MGYG000002478_04323;MGYG000000243_00993 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4656@1|root,COG4656@2|Bacteria,4NIS7@976|Bacteroidetes,2FMAQ@200643|Bacteroidia,4AM9Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4_10,Fer4_17,Fer4_7,Fer4_8,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_04323 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03615:rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 617838 0 269022 0 0 0 0 710871 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1368345 0 462719 0 0 0 0 644415 0 0 0 0 584665 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564250 0 690076 0 0 0 0 573746 0 0 0 0 683145 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 648498 0 1448566 0 0 0 0 1149905 0 0 0 0 1097790 0 0 0 0 0 0 0 0 0 0 +AAQYPGIEVVPLQVKYPQGGEK MGYG000002478_04323;MGYG000000243_00993;MGYG000004797_00718 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG4656@1|root,COG4656@2|Bacteria,4NIS7@976|Bacteroidetes,2FMAQ@200643|Bacteroidia,4AM9Y@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Part of a membrane complex involved in electron transport 1.0 rnfC 1.0 - 1.0 - 1.0 ko:K03615 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4_10,Fer4_17,Fer4_7,Fer4_8,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_04323 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03615:rnfC; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQYVAAH(Oxidation)PGEVC(Carbamidomethyl)PAK MGYG000002494_00621 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,3WV8Q@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 O 1.0 C-terminal domain of 1-Cys peroxiredoxin 1.0 ahpC 1.0 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.0 1.11.1.15 1.0 ko:K03386 1.0 ko04214,map04214 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 1-cysPrx_C,AhpC-TSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00621 1.0 and 1.11.1.29. - - - 1.0 1.0 1.0 1.0 Apoptosis - fly 1.0 K03386:PRDX2_4, ahpC; peroxiredoxin 2/4 [EC:1.11.1.24] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1484660 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAQYVAAHPGEVC(Carbamidomethyl)PAK MGYG000002494_00621 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,3WV8Q@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 O 1.0 C-terminal domain of 1-Cys peroxiredoxin 1.0 ahpC 1.0 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.0 1.11.1.15 1.0 ko:K03386 1.0 ko04214,map04214 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 1-cysPrx_C,AhpC-TSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_00621 1.0 and 1.11.1.29. - - - 1.0 1.0 1.0 1.0 Apoptosis - fly 1.0 K03386:PRDX2_4, ahpC; peroxiredoxin 2/4 [EC:1.11.1.24] 1.0 none 1.0 0 191966 0 0 377889 593769 0 0 0 266798 341981 86658 0 0 0 448183 407050 0 420102 0 255429 498776 0 385911 314288 138577 109217 0 488841 0 0 810761 416035 524058 0 0 345864 303925 1930113 10003453 3402235 0 5820234 9503010 0 0 0 2162398 1885160 1445144 0 0 0 4198554 4497588 0 2964502 0 2801743 13069367 0 8676565 1650221 2212673 1708601 0 3612438 0 0 4611185 4498411 1830894 0 0 1922889 3018309 559812 103925 498192 0 295053 507445 0 0 0 0 0 199632 0 0 0 222019 0 0 563001 0 221729 0 0 311060 0 715950 355462 0 121769 0 0 0 0 170744 0 0 355694 0 131315 331515 802496 0 311926 0 0 0 0 0 436347 339807 0 0 0 484528 227177 0 0 0 0 753921 0 0 405196 194615 257195 0 239642 0 0 221543 0 252559 0 0 108043 0 0 213041 654205 0 0 384328 0 0 0 289019 211533 357884 0 0 0 0 258094 0 0 0 145808 270777 0 397658 295981 365944 0 0 0 0 0 0 0 275359 0 0 255269 225422 +AAQYVASHPGEVC(Carbamidomethyl)PAK MGYG000002506_04802;MGYG000002323_01203;MGYG000000093_02223;MGYG000002513_00687;MGYG000000235_00832;MGYG000002515_02417;MGYG000000337_00350;MGYG000000107_01732 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,3WV8Q@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 O 1.0 C-terminal domain of 1-Cys peroxiredoxin 1.0 ahpC 1.0 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.0 1.11.1.15 1.0 ko:K03386 1.0 ko04214,map04214 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 1-cysPrx_C,AhpC-TSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04802 0.125 and 1.11.1.29. - - - 1.0 1.0 1.0 1.0 Apoptosis - fly 1.0 K03386:PRDX2_4, ahpC; peroxiredoxin 2/4 [EC:1.11.1.24] 1.0 none 1.0 2439390 1546120 1652330 2173035 1256901 3364395 2895668 2697925 1731199 2259637 0 1423695 1102941 1568129 1970192 1316300 0 0 1804618 1744218 2150743 4114819 0 4214758 1962855 1557134 2269503 0 0 1963837 1455536 1816818 1630182 2305207 2227470 1809405 1610801 1580567 1458785 1213813 1724955 1095436 1324276 2757149 1247957 2174623 1805802 2097886 0 1046431 1446884 1395732 1573733 1378774 0 0 1385022 1277478 1392391 3267885 0 2372619 1229587 1462606 1388136 0 0 1613625 1363150 1132972 1629906 1422387 1933391 1053807 1858198 1710378 2383869 2701485 2829071 1205988 3024008 4592692 3595397 3034423 2357082 2515158 0 2152183 2391123 2683125 2138114 2649919 0 0 2540014 2196209 2319373 4270533 0 4175729 2533913 2162590 2070506 0 0 2468134 2017243 0 2985140 3201336 3106084 2288369 1892177 2731908 1963553 1763230 1849328 1994064 1465808 1826776 2586088 1943017 1373666 2011617 0 1263846 1618815 1653996 1365982 1454257 0 0 1131613 1342345 2179425 1627487 0 758814 2196775 1692731 1915991 0 0 1330564 575009 1033513 1506089 3339788 3131504 2654704 1495921 1108073 323159 411627 240721 560802 230810 450439 417455 428012 345235 283616 0 306045 207760 655652 293599 708267 0 0 368552 340406 200339 0 0 293610 265977 305767 0 0 0 289032 308974 479003 230963 468037 513717 359622 313652 389771 +AAQYVASHPGEVC(Delta_H(6)C(3)O(1))PAK MGYG000002506_04802;MGYG000002323_01203;MGYG000000093_02223;MGYG000002513_00687;MGYG000000235_00832;MGYG000002515_02417;MGYG000000337_00350;MGYG000000107_01732 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0450@1|root,COG0450@2|Bacteria,1MWPY@1224|Proteobacteria,1RN4S@1236|Gammaproteobacteria,3WV8Q@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 O 1.0 C-terminal domain of 1-Cys peroxiredoxin 1.0 ahpC 1.0 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.0 1.11.1.15 1.0 ko:K03386 1.0 ko04214,map04214 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 1-cysPrx_C,AhpC-TSA 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_04802 0.125 and 1.11.1.29. - - - 1.0 1.0 1.0 1.0 Apoptosis - fly 1.0 K03386:PRDX2_4, ahpC; peroxiredoxin 2/4 [EC:1.11.1.24] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 229901 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 551885 0 273979 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 429306 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1427888 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1493626 0 852125 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AARIPEKR MGYG000002970_00265;MGYG000001709_01326;MGYG000001567_00563;MGYG000003266_00519;MGYG000002961_01431;MGYG000004681_00352 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4CXT4@84998|Coriobacteriia 0.6666666666666666 84998|Coriobacteriia 1.0 J 1.0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site 1.0 rplS 1.0 - 1.0 - 1.0 - 0.6666666666666666 - 0.6666666666666666 - 0.6666666666666666 - 1.0 - 1.0 - 0.6666666666666666 - 1.0 - 1.0 - 1.0 Ribosomal_L19 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002970_00265 0.16666666666666666 - - - - 1.0 1.0 1.0 1.0 - 0.6666666666666666 - 0.6666666666666666 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AARLFAK MGYG000001602_02095;MGYG000002279_02008;MGYG000000142_01058;MGYG000001338_02036;MGYG000000002_01844;MGYG000000212_02086 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3XZ4K@572511|Blautia 0.5 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000001602_02095 0.16666666666666666 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AARPEDLER MGYG000003022_00085;MGYG000003352_00212 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Burkholderiales|f__Burkholderiaceae|g__Parasutterella 1.0 COG0624@1|root,COG0624@2|Bacteria,1MUSU@1224|Proteobacteria,2VNMJ@28216|Betaproteobacteria 1.0 28216|Betaproteobacteria 1.0 E 1.0 peptidase 1.0 - 1.0 - 1.0 3.4.17.11 1.0 ko:K01295 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01002 1.0 - 1.0 - 1.0 - 1.0 M20_dimer,Peptidase_M20,Peptidase_M28 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003022_00085 0.5 glutamate carboxypeptidase. carboxypeptidase G2. Produced by pseudomonads, Flavobacterium sp. and Acinetobacter sp.-!-Its ability to hydrolyze pteroyl-L-glutamate (folic acid) has led to its use as a folate-depleting, antitumor agent.-!-Belongs to peptidase family M20A. Release of C-terminal glutamate residues from a wide range of N-acylating moieties, including peptidyl, aminoacyl, benzoyl, benzyloxycarbonyl, folyl and pteroyl groups. 1.0 1.0 1.0 1.0 - 1.0 K01295:cpg; glutamate carboxypeptidase [EC:3.4.17.11] 1.0 none 1.0 0 0 0 96095 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1211264 1256963 996506 1310826 0 1655562 0 0 1007303 859868 0 1605034 1238390 0 0 0 0 1192327 0 1211423 0 916209 0 0 0 0 0 0 0 1136215 1181566 1371271 0 1092058 0 1029222 0 0 1183981 811446 828344 1067790 0 1519443 0 0 475223 815248 0 1009313 887332 0 0 0 0 845349 0 882155 0 1065307 0 0 0 0 0 0 0 899080 649653 802431 0 923125 0 682566 0 0 0 382043 320423 0 0 205469 0 0 0 364750 0 217507 715333 0 0 0 0 169923 0 0 0 0 0 0 0 0 0 0 0 0 0 100417 0 137060 0 283174 0 0 0 188584 152018 78763 0 358360 0 0 0 468122 0 324181 137848 0 0 0 0 99513 0 106724 0 270395 0 0 0 0 0 0 0 205471 0 387585 0 286491 0 71452 +AARPQDHSQKVN MGYG000002506_02960 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0088@1|root,COG0088@2|Bacteria,1MXPF@1224|Proteobacteria,1RNNK@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 J 1.0 Forms part of the polypeptide exit tunnel 1.0 rplD 1.0 GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 1.0 - 1.0 ko:K02926 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_L4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002506_02960 1.0 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02926:RP-L4, MRPL4, rplD; large subunit ribosomal protein L4 1.0 none 1.0 376789 0 0 0 0 0 224069 0 0 0 0 0 0 0 0 0 474386 0 0 0 0 0 0 0 0 333516 0 0 0 0 0 0 0 0 0 0 383793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 29966 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 43367 0 272028 0 0 0 0 0 595664 0 0 0 0 0 0 0 0 0 202908 0 0 0 0 0 0 0 0 529167 0 0 0 0 0 0 0 0 0 0 414707 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAS(Deoxy[S](Ser->Ala)GNIIPSSTGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.018867924528301886 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9811320754716981 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10606038 0 0 0 0 0 0 0 0 0 0 0 9440436 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2611269 0 0 0 0 0 0 0 0 2638975 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAS(Deoxy[S](Ser->Ala)SESFGYNEDQIVSSDVIGMR MGYG000002641_00563;MGYG000000195_01135 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002641_00563 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2692770 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1264239 0 0 0 0 0 0 0 0 0 1106253 0 0 0 0 0 0 0 0 0 0 393762 0 1307830 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 351520 950226 0 0 0 0 0 0 0 0 0 0 0 1957803 0 0 0 270873 0 0 0 0 522183 0 0 0 0 0 0 0 383625 0 0 0 546452 0 0 0 0 0 400473 0 0 0 0 0 0 0 0 0 0 0 0 665858 0 +AAS(Formyl[S](Ser->Asp)GNIIPSSTGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.018867924528301886 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9811320754716981 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAS(Methyl[S](Ser->Thr)DLEFSK MGYG000003681_02191;MGYG000001661_01238;MGYG000002561_00276;MGYG000004899_00435;MGYG000001313_00261;MGYG000004185_02017;MGYG000000224_00588 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_02191 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2214163 1888826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1555823 0 0 0 0 2141909 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 792745 +AAS(Methyl[S](Ser->Thr)SESFGYNEDQIVSSDVIGMR MGYG000002641_00563;MGYG000000195_01135 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002641_00563 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 927361 0 0 0 0 0 0 0 0 0 0 0 1306068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 773345 0 0 0 0 0 0 0 0 0 0 0 0 1038668 0 0 0 0 0 0 0 0 0 0 799765 0 0 0 0 0 0 0 0 0 0 0 915795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 683687 0 0 0 0 0 0 0 0 0 0 465896 598045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AAS(Octanoyl)GNIIPSSTGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.018867924528301886 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9811320754716981 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2906958 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASAAEC(Carbamidomethyl)IQLISQGERPLVR MGYG000001300_02023 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii|m__MGYG000001300 1.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,3WGRN@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 F 1.0 phosphoribosylformylglycinamidine synthase 1.0 purL 1.0 - 1.0 6.3.5.3 1.0 ko:K01952 1.0 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 1.0 M00048 1.0 R04463 1.0 RC00010,RC01160 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 AIRS,AIRS_C,GARS_A,GARS_C,GARS_N,GATase_5,PurS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_02023 1.0 phosphoribosylformylglycinamidine synthase. phosphoribosylformylglycinamidine synthetase. - ATP + H2O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-beta-D- ribosyl)glycinamide = 2-formamido-N(1)-(5-O-phospho-beta-D- ribosyl)acetamidine + ADP + H(+) + L-glutamate + phosphate. 1.0 1.0 1.0 1.0 Purine metabolism|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01952:PFAS, purL; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] 1.0 none 1.0 457286 0 0 269331 0 0 321987 0 0 0 0 201154 0 294268 0 0 0 0 402993 0 0 0 0 0 0 269968 0 0 0 0 0 0 0 0 0 385156 256069 0 598493 0 0 747076 0 0 1013959 0 0 0 0 807513 0 890882 0 0 0 0 1127484 0 0 0 0 0 0 1033765 0 0 0 0 0 0 0 0 0 860265 1045634 0 180648 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 122567 0 0 0 0 165234 0 0 0 0 0 0 0 0 0 0 0 0 0 329840 0 0 0 0 0 0 0 0 0 0 188605 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASAAGLSIHVPFAPGR MGYG000002506_03648 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0685@1|root,KOG0564@2759|Eukaryota 1.0 2759|Eukaryota 1.0 E 1.0 methylenetetrahydrofolate reductase (NAD(P)H) activity 1.0 MTHFR1 1.0 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.0 1.5.1.20,3.6.4.12 1.0 ko:K00297,ko:K10901 1.0 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,ko03440,ko03460,map00670,map00720,map01100,map01120,map01200,map01523,map03440,map03460 1.0 M00295,M00377,M00414 1.0 R01224,R07168 1.0 RC00081 1.0 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 1.0 - 1.0 - 1.0 - 1.0 BT1,DEAD,DUF1712,EamA,Helicase_C,Homoserine_dh,Hormone_recep,MTHFR,RecQ_Zn_bind,peroxidase,zf-C4 1.0 - 1.0 - 1.0 - 1.0 AA0 1.0 MGYG000002506_03648 1.0 methylenetetrahydrofolate reductase [NAD(P)H]. | DNA helicase. MTHFR. A flavoprotein (FAD).-!-The enzyme catalyzes the reversible conversion of 5,10- methylenetetrahydrofolate to 5-methyltetrahydrofolate, playing an important role in folate metabolism by regulating the distribution of one-carbon moieties between cellular methylation reactions and nucleic acid synthesis.-!-This enzyme, characterized from Protozoan parasites of the genus Leishmania, is unique among similar characterized eukaryotic enzymes in that it lacks the C-terminal allosteric regulatory domain (allowing it to catalyze a reversible reaction) and uses NADH and NADPH with equal efficiency under physiological conditions. cf. EC 1.5.1.53, EC 1.5.1.54, and EC 1.5.7.1.-!-Formerly EC 1.1.1.68, EC 1.1.1.171, EC 1.1.99.15 and EC 1.7.99.5. | DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA.-!-Some of them unwind duplex DNA with a 3' to 5' polarity, other show 5' to 3' polarity or unwind DNA in both directions.-!-Some helicases unwind DNA as well as RNA.-!-May be identical with EC 3.6.4.13. (1) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH. (2) (6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10- methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH. | ATP + H2O = ADP + H(+) + phosphate. 1.0 1.0 1.0 1.0 One carbon pool by folate|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism|Antifolate resistance|Homologous recombination|Fanconi anemia pathway 1.0 K00297:metF, MTHFR; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]|K10901:BLM, RECQL3, SGS1; bloom syndrome protein [EC:5.6.2.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67054 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 156154 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 811107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASAEEAAALVK MGYG000000133_01784 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 1.0 cdhC 1.0 - 1.0 2.3.1.169 1.0 ko:K14138 1.0 ko00720,ko01120,ko01200,map00720,map01120,map01200 1.0 M00377 1.0 R08433,R10243 1.0 RC00004,RC00113,RC01144,RC02963,RC02964,RC02977 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 CdhC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_01784 1.0 CO-methylating acetyl-CoA synthase. ACS. Involved, together with EC 1.2.7.4 in the synthesis of acetyl-CoA from CO2 and H2. acetyl-CoA + Co(I)-[corrinoid Fe-S protein] + H(+) = CO + CoA + methyl- Co(III)-[corrinoid Fe-S protein]. 1.0 1.0 1.0 1.0 Carbon fixation pathways in prokaryotes|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K14138:acsB; acetyl-CoA synthase [EC:2.3.1.169] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 410741 332286 278235 310652 0 212698 376955 325991 0 0 0 552205 0 494995 0 0 0 1671649 343906 0 557170 267665 1887105 0 0 286994 363988 1917859 275912 0 0 459242 138948 0 0 478106 635509 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 576322 0 0 0 0 0 0 0 0 0 0 3756344 2159542 2427905 4833489 0 1579850 6686302 3596784 2786724 5067893 2547367 3615527 1700718 7132133 5127457 1678628 3399622 556979 3144088 0 5942705 1620280 706489 1698726 4406586 3053663 4130280 1041031 6400104 1358401 1680567 1901850 3007461 4211155 3105438 3773216 2678881 1607205 +AASAELVAK MGYG000004642_00011 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,36EA6@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 - 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4,Fer4_10,Fer4_16,Fer4_7,Fer4_9,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000004642_00011 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 432731 0 0 0 0 0 0 0 0 0 0 588882 0 0 0 0 691101 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3615191 0 0 0 0 0 350135 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1088297 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASAGDFR MGYG000000212_00999 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A obeum|m__MGYG000000212 1.0 COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XZ7S@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Respiratory-chain NADH dehydrogenase 51 Kd subunit 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Complex1_51K,Fer4_10,Fer4_17,RnfC_N,SLBB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_00999 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 171168 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 678142 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 526673 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2181653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASAMVPGDHGTTYGGNPLVTAGAK MGYG000000179_03148 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster aldenensis|m__MGYG000000179 1.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,26803@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 E 1.0 Psort location Cytoplasmic, score 1.0 argD 1.0 - 1.0 2.6.1.11,2.6.1.17 1.0 ko:K00821 1.0 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 1.0 M00016,M00028,M00845 1.0 R02283,R04475 1.0 RC00006,RC00062 1.0 ko00000,ko00001,ko00002,ko01000,ko01007 1.0 - 1.0 - 1.0 - 1.0 Aminotran_3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000179_03148 1.0 acetylornithine transaminase. | succinyldiaminopimelate transaminase. succinylornithine aminotransferase. | succinyldiaminopimelate transferase. Also acts on L-ornithine and N(2)-succinyl-L-ornithine. 2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L- glutamate 5-semialdehyde. | 2-oxoglutarate + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate = (S)-2- succinylamino-6-oxoheptanedioate + L-glutamate. 1.0 1.0 1.0 1.0 Arginine biosynthesis|Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|2-Oxocarboxylic acid metabolism|Biosynthesis of amino acids 1.0 K00821:argD; acetylornithine/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 345949 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 326090 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1773966 0 0 0 0 0 0 0 0 0 0 0 0 2404934 1771101 0 0 0 0 1168126 0 0 0 0 0 1556881 0 0 2296975 0 0 0 0 0 0 0 1389630 0 +AASANIIPSSTGAAK MGYG000004642_01190 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,36DD0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004642_01190 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025251 0 1112522 0 0 0 0 0 0 830037 818665 0 0 0 0 0 802965 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 291802 0 0 0 0 0 0 319464 0 0 0 0 0 0 0 0 246157 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASAPAAPAAN(Deamidated)GGIPK MGYG000000133_00167 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3WS7A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Glucose dehydrogenase C-terminus 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00167 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1434018 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASAPAAPAANGGIPK MGYG000000133_00167 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3WS7A@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Glucose dehydrogenase C-terminus 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ADH_N,ADH_zinc_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_00167 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 994356 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASDEILQLSR MGYG000000489_01608;MGYG000002517_00264 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia,26B8C@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 NT 1.0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). 1.0 - 1.0 - 1.0 - 1.0 ko:K03406 1.0 ko02020,ko02030,map02020,map02030 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko00001,ko02035 1.0 - 1.0 - 1.0 - 1.0 4HB_MCP_1,HAMP,MCPsignal,dCache_1 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000489_01608 0.5 - - - - 1.0 1.0 1.0 1.0 Two-component system|Bacterial chemotaxis 1.0 K03406:mcp; methyl-accepting chemotaxis protein 1.0 none 1.0 320495 0 0 448345 256443 393852 721435 210187 152911 594628 0 424576 0 111030 452857 0 454604 0 654612 412461 434620 383697 0 1524518 452263 315524 0 0 0 229801 0 0 0 383510 1119583 405864 1613419 0 220255 0 0 0 0 227451 379670 0 0 0 0 0 0 0 592279 710592 0 0 246619 0 0 0 0 0 277952 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 350982 0 320775 0 0 0 0 0 0 0 0 261352 0 0 0 304471 197842 0 0 120125 0 0 0 0 0 440996 0 0 0 556449 374777 0 0 0 3492107 0 0 3455960 1528469 1583039 2117097 3028920 3372948 2002997 0 1478838 0 3829811 3558856 1426412 2467724 0 2684698 2981834 2070271 529989 0 535588 3735700 2914181 3881565 0 0 2841711 0 0 0 2379520 3383240 3570071 2994082 0 998852 0 0 357059 472722 913003 1157936 735834 1037423 1400892 0 948820 0 1274920 1564409 801439 934327 0 1148221 817929 1427222 540067 0 960349 1247784 909467 1146755 0 0 918033 0 0 0 1091177 970766 1211367 1478980 0 +AASDEYN(Deamidated)WDLNYGEIAK MGYG000003372_02246;MGYG000002477_02450;MGYG000002494_03646 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,3X1E7@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH 1.0 gnd 1.0 GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.0 1.1.1.343,1.1.1.44 1.0 ko:K00033 1.0 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 1.0 M00004,M00006 1.0 R01528,R10221 1.0 RC00001,RC00539 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 1.0 6PGD,NAD_binding_2 1.0 - 1.0 - 1.0 - 1.0 GT30 1.0 MGYG000003372_02246 0.3333333333333333 phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating). | phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating). 6-PGDH. | phosphogluconic acid dehydrogenase. Highly specific for NAD(+).-!-The enzyme catalyzes both the oxidation and decarboxylation of 6-phospho-D-gluconate.-!-In the bacterium Methylobacillus flagellatus the enzyme participates in a formaldehyde oxidation pathway. cf. EC 1.1.1.44. | The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions.-!-Highly specific for NADP(+). cf. EC 1.1.1.343. 6-phospho-D-gluconate + NAD(+) = CO2 + D-ribulose 5-phosphate + NADH. | 6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Glutathione metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00033:PGD, gnd, gntZ; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASDEYNWDLNYGEIAK MGYG000003372_02246;MGYG000002477_02450;MGYG000002494_03646 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,3X1E7@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH 1.0 gnd 1.0 GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.0 1.1.1.343,1.1.1.44 1.0 ko:K00033 1.0 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 1.0 M00004,M00006 1.0 R01528,R10221 1.0 RC00001,RC00539 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 1.0 6PGD,NAD_binding_2 1.0 - 1.0 - 1.0 - 1.0 GT30 1.0 MGYG000003372_02246 0.3333333333333333 phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating). | phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating). 6-PGDH. | phosphogluconic acid dehydrogenase. Highly specific for NAD(+).-!-The enzyme catalyzes both the oxidation and decarboxylation of 6-phospho-D-gluconate.-!-In the bacterium Methylobacillus flagellatus the enzyme participates in a formaldehyde oxidation pathway. cf. EC 1.1.1.44. | The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions.-!-Highly specific for NADP(+). cf. EC 1.1.1.343. 6-phospho-D-gluconate + NAD(+) = CO2 + D-ribulose 5-phosphate + NADH. | 6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Glutathione metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00033:PGD, gnd, gntZ; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 585681 1144980 1263178 0 1071547 1820122 1345141 0 0 1372033 0 0 0 1200420 0 0 1546407 0 1893751 0 2270429 2165745 0 1849622 2297793 812758 0 0 2222233 2139435 702274 1008424 1417656 1026657 0 849755 766138 1183453 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 241485 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASDGPMAQTK MGYG000002993_01302 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-170|s__CAG-170 sp000432135|m__MGYG000002993 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,2N71Q@216572|Oscillospiraceae 1.0 186801|Clostridia 1.0 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002993_01302 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 886651 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 877865 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASDGPMAQTR MGYG000004526_00639;MGYG000003096_01037;MGYG000002116_00788;MGYG000002720_00092;MGYG000002084_01252;MGYG000004482_01535;MGYG000004196_01067;MGYG000001824_01594;MGYG000003686_02367;MGYG000004276_00122;MGYG000001502_01278;MGYG000002143_01659;MGYG000003266_00955;MGYG000004475_00887;MGYG000002715_01695;MGYG000001086_01249;MGYG000002794_01318;MGYG000001757_01274;MGYG000004508_00787 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,2N71Q@216572|Oscillospiraceae 0.631578947368421 186801|Clostridia 0.8947368421052632 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004526_00639 0.05263157894736842 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 3314085 1981239 2031533 2581764 2208705 2405409 4154388 2734557 2949696 2555779 1915338 0 1951942 3172784 2784583 1933372 1954164 2105349 2417194 2200754 2499487 1966996 2442607 3066948 2926867 2751837 0 3119138 2374776 1599534 2070470 1751844 2259290 3896923 2505323 3171915 3117286 2174275 0 1102791 310797 0 180252 189800 111409 299080 276741 149203 0 0 131894 218558 400468 215156 217220 3154057 216098 103870 316528 245150 0 200598 287158 144258 0 350640 248326 331574 392354 108215 229169 0 0 0 264292 331286 461013 532871 730186 436799 942747 926405 831503 786397 1324358 439269 1179436 0 699463 946018 607126 979974 983233 870064 1130515 848943 616999 546879 667840 713695 716444 630093 0 613012 0 720520 649211 620946 689973 1257723 570132 869352 527285 667772 2000283 1762594 2344059 2354483 1617561 1676545 1817481 3461926 2101062 2064816 1958191 0 1500839 1836146 2973427 1430171 1940753 2924460 1687765 1965408 900700 1912507 1857555 1732162 2792355 2868934 0 2657169 2497451 1531209 1786808 2363718 2085575 2608028 2315518 2094748 2844650 1814748 129428 0 249239 0 467486 384598 885386 821292 0 318183 381589 0 176156 522265 658490 464068 517937 0 343940 378033 336229 107870 160675 1720063 876518 560200 0 228579 0 488276 0 175917 0 832732 660575 243744 530644 279773 +AASDGPMPQTR MGYG000001881_00748;MGYG000003022_00748;MGYG000001008_02651;MGYG000000349_00457;MGYG000004288_00862;MGYG000003022_00735;MGYG000000223_03134;MGYG000001299_01777;MGYG000003352_00730;MGYG000000930_01271 domain d__Bacteria 1.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,3VNVP@526524|Erysipelotrichia 0.5 526524|Erysipelotrichia 0.5 J 1.0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis 1.0 tuf 1.0 - 1.0 - 1.0 ko:K02358 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029,ko04147 1.0 - 1.0 - 1.0 - 1.0 GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001881_00748 0.1 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02358:tuf, TUFM; elongation factor Tu 1.0 none 1.0 290563 262107 391973 103910 0 349057 0 248888 0 210074 202759 326896 357098 183860 0 299521 113303 0 0 0 352550 295369 0 334874 0 227183 199192 0 380343 399179 205021 288317 285474 0 299863 0 256395 0 994521 964325 1306487 1211580 1115270 1115009 0 2314105 0 1192343 1094404 958001 911395 1002561 0 832053 1015905 0 0 0 1283604 1189954 0 781782 0 0 890538 0 1315729 3017601 808110 1148551 1173603 1139929 2345346 0 1012488 922376 615202 1077375 829155 799685 1387090 1068755 0 1111964 0 607514 724463 741006 529615 733902 0 637918 1124765 0 0 0 1072969 1011374 0 1143744 0 777458 467732 0 988169 1752290 944528 1375085 543192 662034 960711 0 403051 789427 367365 819114 402658 490611 643800 654189 0 693776 0 499999 451362 450527 439323 310319 0 411910 712843 0 0 0 410530 552982 0 429300 0 431620 430338 0 644582 445182 347699 1415647 637093 496624 859814 0 511081 624771 169111 0 189733 526880 287846 0 0 204383 0 182976 116998 238873 379432 157040 0 0 0 0 0 0 175824 331124 0 521159 0 168908 0 0 25064 157882 219398 244229 135557 427095 173078 0 0 467508 +AASDKGYLGYIHIGEANR MGYG000000028_01658 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes|s__Anaerostipes hadrus_A|m__MGYG000000028 1.0 COG1082@1|root,COG1082@2|Bacteria,1UYHR@1239|Firmicutes,25C7S@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 8.87 1.0 - 1.0 GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016854,GO:0016857,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050897 1.0 5.1.3.30,5.1.3.31 1.0 ko:K18910 1.0 - 1.0 - 1.0 R10817,R10818 1.0 RC03111,RC03283 1.0 ko00000,ko01000 1.0 - 1.0 - 1.0 - 1.0 AP_endonuc_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000028_01658 1.0 D-psicose 3-epimerase. | D-tagatose 3-epimerase. DPEase. | L-ribulose 3-epimerase. The enzyme is highly specific for D-psicose and shows very low activity with D-tagatose (cf. EC 5.1.3.31). | The enzymes isolated from the bacteria Pseudomonas cichorii, Pseudomonas sp. ST-24, Rhodobacter sphaeroides and Mesorhizobium loti catalyze the epimerization of various ketoses at the C3 position, interconverting D-fructose and D-psicose, D-tagatose and D-sorbose, D-ribulose and D-xylulose, and L-ribulose and L-xylulose.-!-The specificity depends on the species. D-allulose = keto-D-fructose. | (1) keto-D-tagatose = keto-D-sorbose. (2) D-allulose = keto-D-fructose. 1.0 1.0 1.0 1.0 - 1.0 K18910:dpe, lre; D-psicose/D-tagatose/L-ribulose 3-epimerase [EC:5.1.3.30 5.1.3.31] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 158081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1232703 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASDLEFA(Ala->Ser)K MGYG000003367_01391;MGYG000004876_01285;MGYG000002455_01371;MGYG000001780_02426;MGYG000003363_00089;MGYG000001370_01765;MGYG000001346_02094;MGYG000001461_00206 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003367_01391 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2426938 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3599070 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2222596 0 0 0 0 3323983 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASDLEFAK MGYG000003367_01391;MGYG000004876_01285;MGYG000002455_01371;MGYG000001780_02426;MGYG000003363_00089;MGYG000001370_01765;MGYG000001346_02094;MGYG000001461_00206 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003367_01391 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1042533 661419 753124 1027768 895250 1075331 1008388 920143 383352 859546 2196415 1468210 628230 1011275 690266 5828173 988301 873480 1100459 1019833 871585 795863 978030 1072068 498013 1060984 888405 740100 843860 1197375 1007622 415388 865583 1252193 947244 816919 444317 912033 1533086 831860 1279930 1093933 1345213 1078220 931761 1205153 726660 1193118 1123670 2929666 510317 1067176 989294 976709 689681 442795 1006554 807084 1246429 1091777 746845 621885 854686 1128371 1171801 433263 823183 826403 485890 1357767 1196526 1192589 1327746 1258625 870429 1135343 1437423 923397 1383703 1459401 2371283 1655989 1984119 1302005 1674267 1356068 3745383 1616445 1265591 1535746 1202866 1760630 1634143 3226429 5052384 1336735 1492004 1640207 3243221 2054397 1155735 1265909 1203253 2629218 1705445 1677748 1648615 1307326 937963 621207 1114057 2214289 1227920 981198 1932639 949690 1959720 1358515 1726020 1559637 1466099 1654573 1345991 1536962 1740217 2416718 998469 1217430 1347856 1569945 1416754 899175 1755108 1065902 1108894 1256721 974604 1010283 3167185 1433638 1312008 1284915 752619 1740939 977571 1398512 1857436 1856078 1580108 1863168 1425515 1852776 984887 674723 862162 1029559 1629240 1260551 646776 1271795 1347694 867899 4395359 1394187 1517842 620818 960102 882028 962271 3089715 728982 1265384 551853 871072 2162166 1042697 1008839 967369 599427 2098340 1004079 1570687 366286 1273635 493188 1377659 455413 756244 1159676 975775 +AASDLEFSK MGYG000003681_02191;MGYG000001661_01238;MGYG000002561_00276;MGYG000004899_00435;MGYG000001313_00261;MGYG000004185_02017;MGYG000000224_00588 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,4AMCA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003681_02191 0.14285714285714285 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1440758 1401173 1247833 1263301 255144 979071 1527862 1531598 1087183 1215577 791037 469928 942560 1170826 0 1310408 980269 691040 1200667 1174097 1141242 965148 332900 545907 0 1573750 1380114 469015 1292989 214921 474923 1420606 891776 1473649 1573394 1196041 1532569 766045 3280718 1604643 2323765 3307998 1719648 0 2549427 3258424 3511987 4296557 1837341 3273170 0 3541451 0 1683480 2931808 1793610 2975398 2902680 3098187 2022488 2534462 1767155 0 3793749 3160664 2406865 2561766 2816090 1559289 2429169 2141877 3289405 3729278 3479315 3424368 3347054 3237585 2014083 3706616 2985687 3573743 0 4999032 2984951 4300042 3351381 3236930 2545432 2207468 3295650 0 2155793 3269043 12305286 2250872 2388163 3142276 2502269 9646747 4000605 0 3279874 2826259 7516190 3736309 3712161 3874306 2290345 2223997 2494404 3287410 4649833 3724069 0 1638298 1302185 1745776 1693062 1471644 1711442 2140357 1614218 1969003 1779902 1516208 1851791 2148525 1821900 0 2112252 1771197 1374140 2237396 1931607 1270209 1697910 583345 1621823 0 2002435 1712881 1234270 2556580 1688979 1596175 1387902 1395430 1601892 1989034 2194271 1763310 1613264 444706 0 0 359187 0 209552 267761 476476 358145 0 182071 250657 133140 281946 0 258425 377411 1464707 206854 295220 479312 404903 879936 281753 0 237444 278008 306734 333167 358080 194978 0 449482 432755 324791 347263 159283 352593 +AASDVEGVYK MGYG000002485_02066;MGYG000004828_01510 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG1302@1|root,COG1302@2|Bacteria,37AEJ@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 S 1.0 Asp23 family, cell envelope-related function 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Asp23 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002485_02066 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3353560 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASEAATEAAK MGYG000000242_00891 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Enterocloster|s__Enterocloster sp000431375|m__MGYG000000242 1.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,21Z0Q@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 K 1.0 PFAM regulatory protein GntR HTH 1.0 - 1.0 - 1.0 - 1.0 ko:K00375 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03000 1.0 - 1.0 - 1.0 - 1.0 Aminotran_1_2,GntR 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000242_00891 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K00375:K00375; GntR family transcriptional regulator / MocR family aminotransferase 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1379857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASEAVKDAALSC(Carbamidomethyl)DQFFVNHR MGYG000002323_00765;MGYG000002506_04304 genus d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia 1.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,3XMCP@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 ribosomal protein 1.0 rpsB 1.0 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002323_00765 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 670486 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 641241 0 847829 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207641 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 400191 0 142235 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 945693 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 697498 0 783162 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 385151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 258374 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASEAVKDAANSC(Carbamidomethyl)DQFFVNHR MGYG000002494_03066;MGYG000002477_04469 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0052@1|root,COG0052@2|Bacteria,1MU33@1224|Proteobacteria,1RN0Z@1236|Gammaproteobacteria,3XMCP@561|Escherichia 1.0 1236|Gammaproteobacteria 1.0 J 1.0 ribosomal protein 1.0 rpsB 1.0 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_03066 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 742173 901228 739285 0 814364 1406544 0 0 0 903372 0 0 0 0 0 0 768619 0 0 0 939727 2268271 0 1520630 912572 599640 0 0 1095884 0 0 731632 651658 0 0 746762 567104 720848 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASEEYNWDLNYGEIAK MGYG000002506_01508 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Escherichia|s__Escherichia coli_D|m__MGYG000002506 1.0 COG0362@1|root,COG0362@2|Bacteria,1MVV8@1224|Proteobacteria,1RM7P@1236|Gammaproteobacteria,3X1E7@547|Enterobacter 1.0 1236|Gammaproteobacteria 1.0 H 1.0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH 1.0 gnd 1.0 GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.0 1.1.1.343,1.1.1.44 1.0 ko:K00033 1.0 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 1.0 M00004,M00006 1.0 R01528,R10221 1.0 RC00001,RC00539 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iECS88_1305.ECS88_2128,iECW_1372.ECW_m2189,iEKO11_1354.EKO11_1765,iPC815.YPO1541,iWFL_1372.ECW_m2189 1.0 6PGD,NAD_binding_2 1.0 - 1.0 - 1.0 - 1.0 GT30 1.0 MGYG000002506_01508 1.0 phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating). | phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating). 6-PGDH. | phosphogluconic acid dehydrogenase. Highly specific for NAD(+).-!-The enzyme catalyzes both the oxidation and decarboxylation of 6-phospho-D-gluconate.-!-In the bacterium Methylobacillus flagellatus the enzyme participates in a formaldehyde oxidation pathway. cf. EC 1.1.1.44. | The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions.-!-Highly specific for NADP(+). cf. EC 1.1.1.343. 6-phospho-D-gluconate + NAD(+) = CO2 + D-ribulose 5-phosphate + NADH. | 6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Glutathione metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00033:PGD, gnd, gntZ; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] 1.0 none 1.0 0 0 0 0 0 728176 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 839637 0 453202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 708646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 714690 0 608531 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 971925 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 734535 0 849289 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASEFEALR MGYG000002717_02115;MGYG000001661_02103;MGYG000001313_03171;MGYG000000098_00636;MGYG000000054_02931;MGYG000000196_02287;MGYG000003681_00141;MGYG000004763_00640;MGYG000001346_00856 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 0.8888888888888888 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 0.8888888888888888 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002717_02115 0.1111111111111111 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 446351 182559 0 639102 0 573033 629955 626874 193209 0 730905 0 682125 429191 0 0 633421 0 469533 0 0 755810 0 389448 0 478489 0 0 227084 607755 401065 0 0 0 0 774955 442931 0 1296139 773889 1415331 1533000 1199985 1006170 1040344 1381243 1663589 0 1039894 0 767292 1323029 0 0 1230672 0 1049202 0 0 1127176 0 810509 0 1747467 0 0 1234754 1179590 964764 0 1383100 0 0 1321753 1773786 1596493 960885 761283 2023326 1995368 2132375 1653192 2348611 1089678 2071149 0 1698601 0 1369019 1540940 0 0 1584945 0 1251131 0 0 929472 0 1732240 0 1505670 0 0 1508804 1645485 2289251 0 1048036 0 0 2041367 1903453 1690485 1274974 760864 586606 1034863 929161 581166 800052 792309 1237402 0 570251 0 878194 790118 0 0 649386 0 683194 0 0 712793 0 562286 0 1616101 0 0 774452 901412 525092 0 354567 0 0 1428110 1086648 761293 0 0 0 0 0 0 0 829756 1024224 0 786837 0 983253 0 0 0 0 0 0 0 0 0 0 0 0 935365 0 0 0 1324729 0 0 0 0 0 0 219920 0 +AASEFEALRLETEASGK MGYG000002717_02115;MGYG000001313_03171;MGYG000000098_00636;MGYG000000054_02931;MGYG000000196_02287;MGYG000000105_02390;MGYG000003681_00141;MGYG000001346_00856 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002717_02115 0.125 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 296792 0 132940 547900 329843 0 0 478910 0 482489 671464 489638 227630 361015 0 0 463217 0 281665 209733 327518 204545 0 473620 416988 461094 388618 0 487456 687629 465374 389725 251222 394199 483774 350797 399016 286350 721214 0 672489 1027963 778371 589044 0 964656 0 842535 857292 1285285 615200 791370 0 0 714971 0 527372 856759 642168 687504 0 462587 640073 722662 824361 0 419357 860635 252039 912647 558932 613682 890171 687469 785301 750039 662725 0 1038295 945828 995647 913593 0 735033 0 886730 1447706 1165925 638403 823609 0 0 761112 0 819507 995595 896904 579618 0 834180 823632 1246184 652128 0 977183 884413 946687 615719 483588 819213 621176 1179335 761293 928661 713729 0 715795 671222 481009 514012 0 591739 0 522323 527337 858471 567891 566429 0 0 574638 0 656075 499330 993887 541211 0 521754 592211 969896 596842 0 384793 690359 533042 767524 521888 858008 688676 712231 826329 453601 0 0 271305 112781 0 376115 0 280507 0 0 342317 163676 691504 181166 0 0 248115 0 0 350144 200295 420285 0 96073 198796 197110 383748 0 306651 426429 134582 362017 0 622124 410984 209576 330648 266826 +AASEFETLR MGYG000000243_02183 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_02183 1.0 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 1762054 0 3382317 1763870 2775228 1793480 1672727 0 1616535 1381961 1558843 1645076 0 1739656 0 1907835 1887353 0 1694971 0 1635914 1510892 0 2261328 0 1409945 1623092 0 1630444 1761711 3148955 1976300 3214189 2096968 1752990 1858343 1559359 3735184 776080 0 1014064 244857 856544 362571 465431 0 796672 0 309176 0 0 470831 0 805541 660336 0 354830 0 968638 523930 0 371991 0 807694 665020 0 0 845652 680688 0 944405 654730 1169674 658424 0 0 0 0 274344 186121 385360 240696 393890 0 387558 107214 450286 187473 0 0 0 0 346786 0 341399 0 405998 338173 0 273449 0 158165 337882 0 309495 0 740250 398946 199089 258360 257061 297298 267939 305923 212845 0 960819 424950 386536 828506 0 0 316247 453213 476962 189295 0 0 0 438392 453621 0 126215 0 209610 1322125 0 1151383 0 646430 557668 0 460638 728692 362302 642197 805799 492331 330555 300387 558066 818390 305995 0 321133 286277 487950 0 299157 0 0 288877 252255 249603 0 0 0 344773 249281 0 432797 0 302665 440604 0 305412 0 290675 160762 0 0 466159 554684 328253 0 205566 138780 205015 232221 224614 +AASEGATVIAVGR MGYG000000223_01722 genome d__Bacteria|p__Firmicutes|c__Bacilli|o__Erysipelotrichales|f__Erysipelotrichaceae|g__NSJ-61|s__NSJ-61 sp003433845|m__MGYG000000223 1.0 COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,24BVM@186801|Clostridia,27MG8@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 IQ 1.0 Enoyl-(Acyl carrier protein) reductase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 adh_short,adh_short_C2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000223_01722 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASEGELK MGYG000002293_01263;MGYG000002275_01823;MGYG000002834_00628;MGYG000003697_01698 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 0.75 976|Bacteroidetes 1.0 G 0.75 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01263 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 633988 0 660135 0 0 769310 650180 581545 428471 805239 804362 0 0 0 1140300 0 0 1777309 323336 0 0 0 625055 553749 370499 366087 815501 0 679827 0 0 302220 705797 0 0 966733 1149329 0 0 0 0 0 0 310323 402489 0 0 0 0 0 0 0 106953 0 0 0 0 0 0 0 253911 199129 201646 0 335219 0 0 0 0 243843 67147 0 0 0 0 0 0 0 915430 0 0 0 0 0 0 0 0 0 0 0 0 0 0 153143 0 0 0 0 966782 636565 0 888242 0 1284166 0 0 0 0 0 0 0 0 0 0 7249945 0 47565720 0 0 46047962 5495627 16286409 4787464 6682381 32194226 0 5589674 0 7096495 0 0 118084939 7925221 0 0 79888840 34899240 66652310 7219388 8409717 7217444 53106611 5493069 0 26070470 4788153 35057540 0 0 3799386 3026308 62265077 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 248232 0 0 0 0 0 153629 0 0 0 295046 0 0 0 0 0 0 +AASEGPMK MGYG000003372_00674;MGYG000002494_01669 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gapA 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iAPECO1_1312.APECO1_847,iPC815.YPO2157,iUTI89_1310.UTI89_C1975,ic_1306.c2184 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003372_00674 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 11395140 24043545 16849872 0 24340057 35157753 14477937 9075314 8458065 19378590 7874367 11395542 12187006 16499700 7642437 14585971 23304736 0 27042684 7659373 19266253 43530456 0 36863308 16733095 7335386 8613895 0 27106155 13583802 14236057 11919655 13004386 6946731 0 0 9251804 17174482 0 0 0 0 0 0 0 0 0 0 0 0 82464 0 0 0 0 0 0 0 0 0 0 0 0 0 152231 0 0 0 0 0 0 0 0 0 56325 95281 96025 0 0 0 0 0 799862 0 206184 0 0 0 0 0 0 0 0 0 0 160240 0 0 0 0 60862 206639 0 0 131465 0 0 0 0 243867 0 0 148406 0 0 0 0 0 0 0 0 0 307334 0 0 91658 0 0 208926 0 0 0 0 0 94824 0 0 0 122020 0 0 0 0 0 71092 0 0 156678 0 0 0 0 +AASELAR MGYG000003266_00502;MGYG000004396_01646 genus d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella 1.0 COG3173@1|root,COG3173@2|Bacteria,2GIZ4@201174|Actinobacteria,4CV5B@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 S 1.0 Phosphotransferase enzyme family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 APH 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003266_00502 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1162841 3075868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2524431 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASELFNANSK MGYG000003891_01624 genome d__Bacteria|p__Firmicutes_A|c__Clostridia_A|o__Christensenellales|f__CAG-74|g__UBA11524|s__UBA11524 sp000437595|m__MGYG000003891 1.0 COG1653@1|root,COG1653@2|Bacteria,1TW09@1239|Firmicutes,24BZW@186801|Clostridia,36G3C@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K17318 1.0 ko02010,map02010 1.0 M00603 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.29,3.A.1.1.9 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003891_01624 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K17318:lplA; putative aldouronate transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 808409 0 0 0 0 796146 0 0 0 2593321 0 0 1213664 0 2757583 0 0 0 0 2228843 992091 0 0 0 0 957939 0 1111545 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 570954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 405959 0 0 0 0 563294 0 0 0 0 0 0 484038 0 0 0 0 0 0 0 170864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 281743 0 0 0 0 0 0 0 0 467209 0 0 945748 0 0 0 0 0 0 437311 830829 0 0 0 0 0 0 475680 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 445981 0 0 0 0 0 0 0 0 0 0 0 0 0 0 372012 0 0 0 0 304585 0 319378 0 0 +AASES(Ser->Asn)FGYNEDLIVSSDVIGMR MGYG000001255_00370 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_F|m__MGYG000001255 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001255_00370 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1400227 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASETYMYAGC(Carbamidomethyl)K MGYG000002026_00357 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__HGM13010|s__HGM13010 sp900754965|m__MGYG000002026 1.0 COG1804@1|root,COG1804@2|Bacteria,1VUFP@1239|Firmicutes,250CR@186801|Clostridia 1.0 186801|Clostridia 1.0 C 1.0 SnoaL-like domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 SnoaL_4 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002026_00357 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 590598 0 0 0 0 0 0 0 0 0 0 0 893075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASEVFADR MGYG000003074_00497;MGYG000000233_00759;MGYG000002170_01548;MGYG000000205_00656;MGYG000000087_01025;MGYG000000255_01796;MGYG000002445_01460;MGYG000001617_01275 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,249GD@186801|Clostridia,21Y2S@1506553|Lachnoclostridium 1.0 186801|Clostridia 1.0 S 1.0 Belongs to the UPF0271 (lamB) family 1.0 - 1.0 - 1.0 - 1.0 ko:K07160 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 LamB_YcsF 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003074_00497 0.125 - - - - 1.0 1.0 1.0 1.0 - 1.0 K07160:pxpA; 5-oxoprolinase (ATP-hydrolysing) subunit A [EC:3.5.2.9] 1.0 none 1.0 1916376 1157564 801782 1481324 1140592 1153627 1230028 1825697 1260879 1371677 963964 1192881 865540 1456720 1416214 1066516 1147130 0 1513307 1757054 1681826 1297849 0 1108594 1405554 1408378 1494781 0 1224709 1233784 0 1235412 989343 1708978 1555062 1298672 1220605 775168 3659098 3603937 3035110 3394198 3536076 2939806 3039556 3628270 2799943 3640724 2872833 3175407 3075417 2924679 2992592 3232116 3035002 0 2382896 2745463 2898462 3130636 0 3149382 2631670 2596813 3238009 0 3081924 2521338 0 3390640 3674126 3791076 3429018 3645432 3114390 2609647 1481435 1124455 1159144 999778 820389 1131385 1008655 1574210 1279284 1348767 978290 765990 1534572 1199810 1340149 1246428 1184167 0 1879160 1278220 1072675 1351111 0 1292133 1279324 1446969 1766449 0 1335675 1081111 0 1010792 867791 1722363 1315407 1013197 1195836 809343 2415382 2813018 2450484 2128492 2268407 2872593 2308096 2365812 2221730 2677688 2230537 3090802 2401200 2318385 1911150 2067345 2178564 0 2115125 2110125 2033794 2967806 0 2531151 2858038 2257399 2231046 0 2381344 1454784 0 2385818 2833413 2734685 2088422 2850040 1820970 2116879 701978 604124 609509 974949 1018410 850326 1111454 1071408 798455 788340 917662 1115567 778684 799019 692154 906635 689817 0 887090 606464 537147 1025549 0 1044104 834688 1044799 606425 0 1064857 905753 0 924376 879910 1106690 1130375 1103218 943933 874429 +AASEVNKEVK MGYG000002961_01779 genome d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp900542275|m__MGYG000002961 1.0 COG1288@1|root,COG1288@2|Bacteria,2HK5U@201174|Actinobacteria,4CUHK@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 S 1.0 C4-dicarboxylate anaerobic carrier 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 DcuC 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002961_01779 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 399551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 537874 0 0 0 0 0 0 0 0 606954 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496040 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASFLAADAVK MGYG000004885_00824 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotellamassilia|s__|m__MGYG000004885 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004885_00824 1.0 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 145403 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1201818 +AASFLAEGAVK MGYG000002293_00785;MGYG000002603_00166;MGYG000003697_00356 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0166@1|root,COG0166@2|Bacteria,4NDV0@976|Bacteroidetes,2FP20@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the GPI family 1.0 pgi 1.0 - 1.0 5.3.1.9 1.0 ko:K01810 1.0 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00004,M00114 1.0 R02739,R02740,R03321 1.0 RC00376,RC00563 1.0 ko00000,ko00001,ko00002,ko01000,ko04147 1.0 - 1.0 - 1.0 - 1.0 PGI 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_00785 0.3333333333333333 glucose-6-phosphate isomerase. phosphosaccharomutase. The enzyme from yeast catalyzes the reversible conversion specifically between the alpha-D-glucose 6-phosphate and beta-D- fructofuranose 6-phosphate.-!-The enzyme also catalyzes the anomerization of both D-hexose 6-phosphates. alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Pentose phosphate pathway|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01810:GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231168 0 0 0 0 0 0 0 0 0 329375 0 0 0 0 0 0 0 0 0 239133 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409842 0 0 0 0 0 0 0 0 0 471864 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1161958 0 0 854462 0 0 0 0 0 0 0 0 0 0 0 2753599 0 0 0 1149347 4796338 729558 0 0 0 1655491 0 0 0 0 734046 0 0 0 0 0 0 0 433750 0 0 967902 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 375372 0 860824 0 0 0 603550 0 0 0 0 0 0 0 0 0 443094 +AASFQETTK MGYG000000142_00116;MGYG000000358_00901;MGYG000000146_01134;MGYG000000231_01252;MGYG000000245_03244;MGYG000003542_00717;MGYG000000303_00569;MGYG000002996_00996;MGYG000004869_02970;MGYG000000164_01117;MGYG000000198_01126;MGYG000000271_03640;MGYG000000414_00671;MGYG000002156_00754;MGYG000001707_01472;MGYG000000193_02078;MGYG000000003_02519;MGYG000002517_00198;MGYG000004757_00585;MGYG000002057_01071;MGYG000003465_01532;MGYG000001714_01233;MGYG000002549_02931;MGYG000001683_01329;MGYG000003514_00770;MGYG000004536_01758;MGYG000002478_00805;MGYG000001338_03383;MGYG000000042_01430;MGYG000000233_00816;MGYG000001789_00145;MGYG000001666_00329;MGYG000000002_03603;MGYG000000127_00619;MGYG000000236_01798;MGYG000004763_01698;MGYG000004658_01196;MGYG000004561_01031;MGYG000001315_01195;MGYG000003493_00375;MGYG000002560_00228;MGYG000001415_02506;MGYG000000243_01979;MGYG000002926_00451;MGYG000004884_01728;MGYG000004630_01089;MGYG000000255_01999;MGYG000003684_05128;MGYG000002298_02601;MGYG000000312_01432;MGYG000000251_01868;MGYG000004885_00605;MGYG000001615_01701;MGYG000000170_00064;MGYG000000196_03983;MGYG000000179_00949;MGYG000003374_00512;MGYG000004797_04274;MGYG000001319_01768;MGYG000001617_00231;MGYG000001464_02079 domain d__Bacteria 1.0 COG0086@1|root,COG0086@2|Bacteria,4NEMW@976|Bacteroidetes,2FMWR@200643|Bacteroidia,4AKMJ@815|Bacteroidaceae 0.18032786885245902 186801|Clostridia 0.5409836065573771 K 1.0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates 0.9836065573770492 rpoC 1.0 - 0.5737704918032787 2.7.7.6 1.0 ko:K03046 1.0 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 1.0 M00183 1.0 R00435,R00441,R00442,R00443 1.0 RC02795 1.0 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 1.0 - 1.0 - 1.0 - 1.0 RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 0.9508196721311475 - 1.0 - 1.0 - 1.0 GH1 1.0 MGYG000000142_00116 0.01639344262295082 DNA-directed RNA polymerase. RNA polymerase III. Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.-!-Can initiate a chain de novo.-!-In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.-!-See also EC 2.7.7.19 and EC 2.7.7.48. a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1). 1.0 1.0 1.0 1.0 Purine metabolism|Pyrimidine metabolism|Metabolic pathways|RNA polymerase 1.0 K03046:rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6] 1.0 none 1.0 0 0 1714354 0 0 1032197 0 0 0 0 0 0 0 0 0 1912679 942711 2555099 0 1281165 0 1165904 1661035 811881 0 0 0 1565183 0 1041582 0 0 1685415 1297147 0 0 0 1477941 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 255335 0 0 0 0 0 0 0 0 0 0 96486 0 0 0 0 0 0 0 0 0 0 0 0 325796 503043 379078 0 475035 0 240496 322178 0 0 0 0 204989 0 401218 0 0 0 299208 0 0 0 321914 0 0 1398804 0 0 1027860 0 0 0 0 0 0 0 0 0 1128496 1471595 523207 0 1258651 0 1549338 460442 1601419 0 0 0 974191 0 1500610 0 0 1286702 526796 0 0 0 1800533 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 53936 0 0 0 0 0 0 0 0 +AASFQYC(Carbamidomethyl)GLR MGYG000000089_01597 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3WGK9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Glycosyltransferase family 36 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Glyco_hydro_36,Glyco_transf_36 1.0 2.4.1.49 1.0 GH94 1.0 GH94 1.0 GH94 1.0 MGYG000000089_01597 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 157738 0 0 0 0 1075914 0 0 0 0 937553 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 204953 0 0 0 0 0 0 0 0 0 164364 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 413914 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 183259 0 0 0 0 185191 0 0 0 0 248725 0 0 0 0 0 0 0 0 0 0 +AASGDLSQIAK MGYG000000002_00048;MGYG000000133_00983;MGYG000000301_01136;MGYG000004733_00770 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3XZIM@572511|Blautia 1.0 186801|Clostridia 1.0 H 1.0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) 1.0 dapA 1.0 - 1.0 4.3.3.7 1.0 ko:K01714 1.0 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 1.0 M00016,M00525,M00526,M00527 1.0 R10147 1.0 RC03062,RC03063 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 DHDPS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000002_00048 0.25 4-hydroxy-tetrahydrodipicolinate synthase. dihydrodipicolinate synthetase. The reaction can be divided into three consecutive steps: Schiff base formation with pyruvate, the addition of L-aspartate-semialdehyde, and finally transimination leading to cyclization with simultaneous dissociation of the product.-!-The product of the enzyme was initially thought to be (S)-2,3- dihydrodipicolinate, and the enzyme was classified accordingly as EC 4.2.1.52.-!-Later studies of the enzyme from the bacterium Escherichia coli have suggested that the actual product of the enzyme is (2S,4S)-4-hydroxy- 2,3,4,5-tetrahydrodipicolinate, and thus the enzyme has been reclassified as 4-hydroxy-tetrahydrodipicolinate synthase.-!-However, the identity of the product is still controversial, as more recently it has been suggested that it may be (S)-2,3- dihydrodipicolinate after all.-!-Formerly EC 4.2.1.52. L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5- tetrahydrodipicolinate + H(+) + H2O. 1.0 1.0 1.0 1.0 Monobactam biosynthesis|Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K01714:dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7] 1.0 none 1.0 371113 406065 1192285 0 0 1516381 0 0 0 0 1066124 0 697725 0 808441 786651 0 0 0 0 1179071 1621065 0 760996 740123 351636 229936 0 1547345 0 0 485060 638022 0 0 444569 487169 777009 0 382620 265853 0 0 0 0 0 0 0 116771 0 124015 0 0 191311 0 0 0 0 121289 140404 0 240614 129342 0 113829 0 118159 0 0 0 330856 0 0 121878 0 106127 1028366 329516 544543 0 0 977886 0 0 0 0 581400 0 456899 0 1142936 734952 0 0 0 0 605456 1376713 0 767912 694959 604099 1049318 0 814999 0 0 824510 813036 0 0 701678 872459 1031804 0 0 0 0 0 0 0 0 0 0 0 0 302380 0 161087 138733 0 0 0 0 477107 351421 0 533801 0 0 0 0 1787635 0 0 0 390318 0 0 0 0 332746 2614332 2558525 2867802 0 0 1492536 0 0 0 0 2320223 0 1839887 0 3008398 2188134 0 0 0 0 3309109 2417582 0 1477713 2439899 3573544 3211538 0 4205246 0 0 3776483 3949202 0 0 2378014 1695232 0 +AASGGGYAISIK MGYG000002171_00690;MGYG000002560_02614;MGYG000002478_00950 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola 1.0 COG1082@1|root,COG1082@2|Bacteria,4NEWC@976|Bacteroidetes,2FKZT@200643|Bacteroidia,4AMS4@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 G 1.0 COG NOG06228 non supervised orthologous group 1.0 susB 1.0 GO:0000272,GO:0003674,GO:0003824,GO:0004339,GO:0004553,GO:0004558,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015926,GO:0016020,GO:0016052,GO:0016787,GO:0016798,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044464,GO:0046872,GO:0071704,GO:0071944,GO:0090599,GO:1901575 1.0 3.2.1.20,3.2.1.3 1.0 ko:K01187,ko:K21574 1.0 ko00052,ko00500,ko01100,map00052,map00500,map01100 1.0 - 1.0 R00028,R00801,R00802,R01790,R01791,R06087,R06088 1.0 RC00028,RC00049,RC00077 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH31,GH97 1.0 - 1.0 GH97_C,GH97_N,Glyco_hydro_97 1.0 3.2.1.3|3.2.1.20 1.0 GH97 1.0 GH97 1.0 GH97 1.0 MGYG000002171_00690 0.3333333333333333 alpha-glucosidase. | glucan 1,4-alpha-glucosidase. maltase-glucoamylase. | lysosomal alpha-glucosidase. Group of enzymes whose specificity is directed mainly toward the exohydrolysis of 1,4-alpha-glucosidic linkages, and that hydrolyze oligosaccharides rapidly, relative to polysaccharides, which are hydrolyzed relatively slowly, or not at all.-!-The intestinal enzyme also hydrolyzes polysaccharides, catalyzing the reactions of EC 3.2.1.3, and, more slowly, hydrolyzes 1,6-alpha-D- glucose links. | Most forms of the enzyme can rapidly hydrolyze 1,6-alpha-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyze 1,6- and 1,3-alpha-D-glucosidic bonds in other polysaccharides.-!-This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides.-!-EC 3.2.1.20 from mammalian intestine can catalyze similar reactions. Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose. | Hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D- glucose. 1.0 1.0 1.0 1.0 Galactose metabolism|Starch and sucrose metabolism|Metabolic pathways 1.0 K01187:malZ; alpha-glucosidase [EC:3.2.1.20]|K21574:susB; glucan 1,4-alpha-glucosidase [EC:3.2.1.3] 1.0 none 1.0 0 0 1091429 0 2053080 0 1629045 0 0 0 0 0 0 1279800 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1326596 0 0 0 0 1247714 0 0 0 0 556939 0 0 0 0 0 0 0 0 418767 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 393162 0 0 0 0 0 0 0 0 0 938090 0 499625 0 0 0 0 0 0 526443 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 171743 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 386199 0 488055 0 527887 0 0 0 0 0 0 347118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 371594 +AASGN(Deamidated)IIPSSTGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.018867924528301886 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9811320754716981 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASGNIIPS(Formyl[S](Ser->Asp)STGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.018867924528301886 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9811320754716981 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASGNIIPSS(Formyl[S](Ser->Asp)TGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.018867924528301886 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9811320754716981 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASGNIIPSST(Formyl[T](Thr->Glu)GAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.018867924528301886 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9811320754716981 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9811320754716981 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASGNIIPSSTGAAK MGYG000004468_00660;MGYG000002540_02142;MGYG000003831_00170;MGYG000001783_01519;MGYG000003457_01802;MGYG000004006_01717;MGYG000000354_00611;MGYG000004241_01079;MGYG000002007_00386;MGYG000004756_01346;MGYG000004748_00450;MGYG000001345_01069;MGYG000002934_01252;MGYG000001562_00044;MGYG000004464_00783;MGYG000002926_01713;MGYG000002478_03999;MGYG000001313_02393;MGYG000001415_02219;MGYG000004536_01441;MGYG000000243_01331;MGYG000000273_02725;MGYG000002275_01823;MGYG000000099_02094;MGYG000002281_04045;MGYG000000043_01774;MGYG000000044_01948;MGYG000004479_00217;MGYG000003312_01022;MGYG000002455_02200;MGYG000001546_00360;MGYG000004726_03349;MGYG000000445_00706;MGYG000003252_01337;MGYG000001762_01533;MGYG000002095_00148;MGYG000003202_00946;MGYG000000003_00712;MGYG000002933_02039;MGYG000000196_00479;MGYG000001643_00773;MGYG000003693_00860;MGYG000003819_01468;MGYG000002549_00455;MGYG000002737_00455;MGYG000001789_00244;MGYG000000053_01377;MGYG000000170_00182;MGYG000000673_01725;MGYG000002675_01717;MGYG000002035_01208;MGYG000002905_02083;MGYG000004469_01500 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.49056603773584906 976|Bacteroidetes 0.8301886792452831 C 0.5283018867924528 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.8867924528301887 gap 0.9433962264150944 - 0.9811320754716981 1.2.1.12 0.9811320754716981 ko:K00134 0.9811320754716981 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 0.9811320754716981 M00001,M00002,M00003,M00165,M00166,M00308,M00552 0.9811320754716981 R01061 0.9811320754716981 RC00149 0.9811320754716981 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 0.9811320754716981 - 1.0 - 1.0 - 0.9811320754716981 Gp_dh_C,Gp_dh_N 0.9811320754716981 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004468_00660 0.018867924528301886 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 0.9811320754716981 0.9811320754716981 0.9811320754716981 0.9811320754716981 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 0.9811320754716981 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 0.9811320754716981 none 1.0 62639635 66764785 93392708 74990391 75775296 53883645 81834848 57887472 63298580 58009355 85864117 65292478 84779177 56537727 42757444 93284179 62085524 30234292 55898241 61392982 67073774 55082350 46290285 82671794 46761551 60936186 82574198 49917918 64126249 72976788 105684034 85268344 117651407 49417734 63440663 69461220 70768584 102618709 48682019 44456163 57664745 56527569 78773218 55152139 49344707 60582219 58155967 64449745 101478479 63166482 110953738 65104304 56405787 84802957 59467430 82044923 48625157 44992746 54836940 53499194 125303313 49582208 53971303 56928903 56133489 93549803 53699577 50580602 42004570 61109285 61296916 49973836 62157841 62430595 62323181 63616804 53535082 46840794 68024880 46205652 95142987 69954403 63161754 46479478 58386318 44416369 89041083 59152229 77694125 50344442 41254320 65897975 55203294 114600150 49390783 40909142 46806315 47709491 80359304 58645032 42559972 44480477 46056590 73496587 54378402 54405485 67708205 51564792 46701061 45121673 51781021 62267427 46337197 53784867 14942155 6300214 8211166 8376283 9341712 7446491 13215517 15501385 9562180 7194986 13535534 18992579 15137270 11220631 14458049 8438871 6761419 3323804 7981689 7272638 13237958 4497314 5994631 1962029 18216237 20943948 12325289 0 5413803 9877826 3590805 12804584 7978871 21724381 20795200 19155783 17634990 3846956 47562118 33261272 38909282 57427631 83846639 62711394 57210682 59622467 60238626 37953259 89639695 52032722 94648011 34380314 43794370 81440221 46605125 145728521 46241555 56681902 39166596 51271606 116696708 52697286 50152152 79336836 44778600 108167544 56659040 68122435 43897588 51442313 32588331 63868822 48425543 48366984 54908547 46609286 +AASGNIIPSSTGAAKAVGK MGYG000004536_01441;MGYG000000196_00479;MGYG000000243_01331;MGYG000001562_00044;MGYG000000044_01948;MGYG000004756_01346;MGYG000002478_03999;MGYG000000170_00182;MGYG000001415_02219;MGYG000004748_00450 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,22V16@171550|Rikenellaceae 0.5 976|Bacteroidetes 1.0 G 0.5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004536_01441 0.1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASGNIIPSTTGAAK MGYG000002556_00846;MGYG000003363_01174 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia,4AKZB@815|Bacteroidaceae 0.5 976|Bacteroidetes 1.0 C 0.5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002556_00846 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 956339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1006495 0 0 2860086 0 0 0 0 2538943 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASGQVAVLK MGYG000002517_01061 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia 1.0 186801|Clostridia 1.0 E 1.0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate 1.0 dapB 1.0 - 1.0 1.17.1.8 1.0 ko:K00215 1.0 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 1.0 M00016,M00525,M00526,M00527 1.0 R04198,R04199 1.0 RC00478 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 iHN637.CLJU_RS17035 1.0 ACT,ACT_7,DapB_C,DapB_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01061 1.0 4-hydroxy-tetrahydrodipicolinate reductase. dihydrodipicolinate reductase. The substrate of the enzyme was initially thought to be (S)-2,3- dihydrodipicolinate, and the enzyme was classified accordingly as EC 1.3.1.26.-!-Later studies of the enzyme from the bacterium Escherichia coli have suggested that the actual substrate of the enzyme is (2S,4S)-4- hydroxy-2,3,4,5-tetrahydrodipicolinate, and that its activity includes a dehydration step, and thus the enzyme has been reclassified as 4-hydroxy-tetrahydrodipicolinate reductase.-!-However, the identity of the substrate is still controversial, as more recently it has been suggested that it may be (S)-2,3- dihydrodipicolinate after all.-!-Formerly EC 1.3.1.26. (1) (S)-2,3,4,5-tetrahydrodipicolinate + H2O + NAD(+) = (2S,4S)-4- hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH. (2) (S)-2,3,4,5-tetrahydrodipicolinate + H2O + NADP(+) = (2S,4S)-4- hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH. 1.0 1.0 1.0 1.0 Monobactam biosynthesis|Lysine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Biosynthesis of amino acids 1.0 K00215:dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 2946746 1610574 0 0 0 0 0 0 0 0 0 0 0 562076 0 0 0 0 0 0 0 0 1868622 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 640844 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1141952 1159773 0 0 0 0 0 260951 0 0 0 0 0 922517 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1224653 1653600 0 1770165 0 0 0 1449601 0 0 0 0 0 1379069 0 0 0 0 0 0 0 0 3723304 0 0 +AASGQYETTLMSEMEK MGYG000001300_01498;MGYG000002274_02019 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001300_01498 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 773889 0 0 0 0 0 0 0 0 0 1476497 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASGVILITTK MGYG000002438_02062 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Tannerellaceae|g__Parabacteroides|s__Parabacteroides distasonis|m__MGYG000002438 1.0 COG1629@1|root,COG1629@2|Bacteria,COG4771@2|Bacteria,4NDXS@976|Bacteroidetes,2FKYX@200643|Bacteroidia,22WRD@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 P 1.0 TonB dependent receptor 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 CarbopepD_reg_2,Plug,TonB_dep_Rec 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002438_02062 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 196028 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 787609 0 0 0 0 0 0 0 0 +AASHFVELYLK MGYG000002834_01040;MGYG000003697_02150;MGYG000002603_01099;MGYG000002293_02393 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0246@1|root,COG0246@2|Bacteria,4NEMT@976|Bacteroidetes,2FP8Z@200643|Bacteroidia,4ATAV@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 C 1.0 Mannitol dehydrogenase Rossmann domain 1.0 uxuB 1.0 - 1.0 1.1.1.17,1.1.1.58,1.1.1.67 1.0 ko:K00009,ko:K00041,ko:K00045 1.0 ko00040,ko00051,ko01100,map00040,map00051,map01100 1.0 M00631 1.0 R00868,R02555,R02703 1.0 RC00085 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 Mannitol_dh,Mannitol_dh_C 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002834_01040 0.25 mannitol-1-phosphate 5-dehydrogenase. | tagaturonate reductase. | mannitol 2-dehydrogenase. Tagaturonate dehydrogenase. | mannitol dehydrogenase. - D-mannitol 1-phosphate + NAD(+) = beta-D-fructose 6-phosphate + H(+) + NADH. | D-altronate + NAD(+) = H(+) + keto-D-tagaturonate + NADH. | D-mannitol + NAD(+) = D-fructose + H(+) + NADH. 1.0 1.0 1.0 1.0 Pentose and glucuronate interconversions|Fructose and mannose metabolism|Metabolic pathways 1.0 K00009:mtlD; mannitol-1-phosphate 5-dehydrogenase [EC:1.1.1.17]|K00041:uxaB; tagaturonate reductase [EC:1.1.1.58]|K00045:E1.1.1.67, mtlK; mannitol 2-dehydrogenase [EC:1.1.1.67] 1.0 none 1.0 0 0 132152 0 0 267354 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 113326 0 0 0 0 0 0 0 0 0 0 364020 0 0 0 0 56591 0 0 0 0 0 286795 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 47551 0 0 0 0 0 0 0 0 0 0 91375 0 0 0 0 0 0 0 1417226 0 0 12348842 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 16081484 0 12497775 0 0 0 0 0 0 0 0 1745585 0 0 0 0 1687414 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASHQVEASLMDLK MGYG000003693_00561 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola plebeius_A|m__MGYG000003693 1.0 COG1538@1|root,COG1538@2|Bacteria,4NDZK@976|Bacteroidetes,2FND5@200643|Bacteroidia,4AKYA@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 MU 1.0 Efflux transporter, outer membrane factor lipoprotein, NodT family 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OEP 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003693_00561 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 758468 0 0 0 0 889530 0 0 0 0 617202 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 216824 0 0 0 0 0 0 0 0 0 0 +AASINM(Oxidation)PYVNER MGYG000002603_00738;MGYG000003697_01279;MGYG000002960_02181;MGYG000002293_01728 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002603_00738 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 789169 0 0 0 0 1175067 0 0 0 0 0 0 0 0 0 0 1136827 0 1334136 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASINMPYVNER MGYG000002603_00738;MGYG000003697_01279;MGYG000002960_02181;MGYG000002293_01728 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0052@1|root,COG0052@2|Bacteria,4NER0@976|Bacteroidetes,2FM4T@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Belongs to the universal ribosomal protein uS2 family 1.0 rpsB 1.0 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 1.0 - 1.0 ko:K02967 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 HHH_5,Phosphatase,Ribosomal_S2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002603_00738 0.25 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02967:RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8074178 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASITTSR MGYG000000022_02871;MGYG000002274_00380;MGYG000003166_01072 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3WGC8@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.7.1.4 1.0 ko:K00847 1.0 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 1.0 - 1.0 R00760,R00867,R03920 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 PfkB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_02871 0.3333333333333333 fructokinase. D-fructokinase. - ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Fructose and mannose metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways 1.0 K00847:E2.7.1.4, scrK; fructokinase [EC:2.7.1.4] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1056552 0 0 0 0 1221360 0 0 0 0 1228460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 985489 0 0 0 0 1317089 0 0 0 0 1572144 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 286369 0 0 0 0 822475 0 0 0 0 1716837 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 859878 0 0 0 0 262855 0 0 0 0 644244 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1231395 0 0 0 0 1527175 0 0 0 0 1303938 0 0 0 0 0 0 0 0 0 0 +AASLGNDAGIYGAVR MGYG000002545_01664;MGYG000002040_01652 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3WHF9@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 GK 1.0 Psort location Cytoplasmic, score 1.0 - 1.0 - 1.0 2.7.1.2 1.0 ko:K00845 1.0 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 1.0 M00001,M00549 1.0 R00299,R01600,R01786 1.0 RC00002,RC00017 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 ROK 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002545_01664 0.5 glucokinase. glucose kinase. A group of enzymes found in invertebrates and microorganisms highly specific for glucose. ATP + D-glucose = ADP + D-glucose 6-phosphate + H(+). 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Galactose metabolism|Starch and sucrose metabolism|Amino sugar and nucleotide sugar metabolism|Streptomycin biosynthesis|Neomycin, kanamycin and gentamicin biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K00845:glk; glucokinase [EC:2.7.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 507696 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 538307 0 0 0 0 615769 0 0 0 0 507644 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 753081 0 0 0 0 716983 0 0 0 0 614474 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 561339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASLNPNSDEAK MGYG000002556_01677 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Muribaculaceae|g__CAG-279|s__CAG-279 sp000437795|m__MGYG000002556 1.0 COG0457@1|root,COG0457@2|Bacteria,4NIJG@976|Bacteroidetes,2FPCN@200643|Bacteroidia,22WME@171551|Porphyromonadaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 OmpA,TPR_1,TPR_11,TPR_16,TPR_17,TPR_2,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002556_01677 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2327818 0 0 0 0 1918990 0 0 0 0 1791977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 324503 0 0 0 0 0 0 0 0 0 117743 0 0 0 0 0 0 0 0 0 0 +AASLNPTMIQNIAN(Deamidated)GR MGYG000002080_00437;MGYG000003697_01278;MGYG000002960_02182 genus d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella 1.0 COG0264@1|root,COG0264@2|Bacteria,4NF03@976|Bacteroidetes,2FNAD@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 J 1.0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome 1.0 tsf 1.0 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.0 - 1.0 ko:K02357 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko03012,ko03029 1.0 - 1.0 - 1.0 - 1.0 EF_TS 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002080_00437 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K02357:tsf, TSFM; elongation factor Ts 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 917777 634963 1194776 0 0 1077537 488452 768790 0 0 1231730 738597 715006 0 694838 0 0 0 0 0 0 1323287 0 642874 655793 830159 842060 0 0 0 0 951315 1176833 1050337 761297 960062 897705 853044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASLTGAGATFPAPVYAK MGYG000002504_04275;MGYG000002494_02400;MGYG000002477_00650 family d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae 1.0 COG0226@1|root,COG0226@2|Bacteria,1MUAZ@1224|Proteobacteria,1RN5Q@1236|Gammaproteobacteria 1.0 1236|Gammaproteobacteria 1.0 P 1.0 Part of the ABC transporter complex PstSACB involved in phosphate import 1.0 pstS 1.0 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 1.0 - 1.0 ko:K02040 1.0 ko02010,ko02020,ko05152,map02010,map02020,map05152 1.0 M00222 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.7 1.0 - 1.0 iECH74115_1262.ECH74115_5157,iECSP_1301.ECSP_4770,iECs_1301.ECs4664,iG2583_1286.G2583_4518,iJN746.PP_2656,iZ_1308.Z5219 1.0 PBP_like_2 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002504_04275 0.3333333333333333 - - - - 1.0 1.0 1.0 1.0 ABC transporters|Two-component system|Tuberculosis 1.0 K02040:pstS; phosphate transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 911500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1021607 0 834848 0 0 0 0 905259 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASMADSKADEGTNNSLSPTFIIK MGYG000002293_01225 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella sp900557255|m__MGYG000002293 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002293_01225 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 1018454 0 0 0 0 0 0 663893 0 0 0 0 2140398 0 0 0 0 1631702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 346702 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 752645 0 0 0 0 0 0 1530256 0 0 0 0 2218496 0 0 0 0 687813 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 715653 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASMADSKAEDDANNSLSPAFLIK MGYG000003697_01656 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella copri_A|m__MGYG000003697 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003697_01656 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 277846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 174292 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1478766 0 0 794513 0 0 0 0 931973 0 0 0 0 0 0 1351890 0 0 0 972423 2262214 692444 0 0 0 1012629 0 0 0 0 956878 0 0 0 0 847074 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASMDEINNFAK MGYG000000217_02630 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Acetatifactor|s__Acetatifactor sp900066565|m__MGYG000000217 1.0 COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,27J20@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 amyE 1.0 - 1.0 - 1.0 ko:K10117 1.0 ko02010,map02010 1.0 M00196 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1.28 1.0 - 1.0 - 1.0 SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 GH49 1.0 MGYG000000217_02630 1.0 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K10117:msmE; raffinose/stachyose/melibiose transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1856038 0 0 0 0 2210365 0 0 0 0 2004500 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 797963 0 0 0 0 931304 0 0 0 0 939294 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 427301 0 0 0 0 418473 0 0 0 0 480746 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573157 0 0 0 0 362355 0 0 0 0 0 0 0 0 0 0 +AASMLLK MGYG000001346_03304 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Bacteroides|s__Bacteroides uniformis|m__MGYG000001346 1.0 COG0457@1|root,COG0457@2|Bacteria,4PKF6@976|Bacteroidetes,2FNWT@200643|Bacteroidia,4ANQH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 S 1.0 Tetratricopeptide repeat protein 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 PPR,TPR_12,TPR_16,TPR_2,TPR_21,TPR_6,TPR_7,TPR_8 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001346_03304 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 531081 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1337250 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1077747 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1527903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1614368 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASMSPYFSMPNMR MGYG000002517_01769 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia hominis|m__MGYG000002517 1.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia 1.0 186801|Clostridia 1.0 G 1.0 Phosphotransfer between the C1 and C5 carbon atoms of pentose 1.0 deoB 1.0 - 1.0 5.4.2.7 1.0 ko:K01839 1.0 ko00030,ko00230,map00030,map00230 1.0 - 1.0 R01057,R02749 1.0 RC00408 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 DeoC,Metalloenzyme 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002517_01769 1.0 phosphopentomutase. phosphodeoxyribomutase. Also converts 2-deoxy-alpha-D-ribose 1-phosphate into 2-deoxy-D- ribose 5-phosphate.-!-alpha-D-ribose 1,5-bisphosphate, 2-deoxy-alpha-D-ribose 1,5- bisphosphate, or alpha-D-glucose 1,6-bisphosphate can act as cofactor.-!-Formerly EC 2.7.5.6. alpha-D-ribose 1-phosphate = D-ribose 5-phosphate. 1.0 1.0 1.0 1.0 Pentose phosphate pathway|Purine metabolism 1.0 K01839:deoB; phosphopentomutase [EC:5.4.2.7] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 857137 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 961993 1521507 0 0 0 0 0 0 0 0 1139983 1942916 0 +AASN(Deamidated)C(Carbamidomethyl)ELAFDNVIVPEENR MGYG000004642_01567 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004642_01567 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 675128 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASN(Deamidated)ESFGYNEDEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 496285 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 125592 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASN(Deamidated)ESFGYNEDQIVSSDIVGMR MGYG000001315_01699 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01699 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 524699 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASN(Deamidated)ESFGYNTDQIVSSDIVGMR MGYG000000249_01352 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_01352 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 467487 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 469363 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1544788 0 0 0 0 276805 +AASN(Deamidated)GELVAK MGYG000002926_00667;MGYG000002156_01167;MGYG000001824_00563;MGYG000002143_01899;MGYG000002720_00858;MGYG000002794_00766;MGYG000004487_00300 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG3246@1|root,COG3246@2|Bacteria,4NGNQ@976|Bacteroidetes,2FQZR@200643|Bacteroidia,22WVP@171551|Porphyromonadaceae 0.8571428571428571 976|Bacteroidetes 0.8571428571428571 S 1.0 3-keto-5-aminohexanoate cleavage protein 0.8571428571428571 - 0.8571428571428571 - 1.0 2.3.1.247 1.0 ko:K18013 1.0 ko00310,map00310 1.0 - 1.0 R10564 1.0 RC02728,RC03199 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 BKACE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_00667 0.14285714285714285 3-keto-5-aminohexanoate cleavage enzyme. - The enzyme, isolated from the bacteria Fusobacterium nucleatum and Cloacimonas acidaminovorans, is involved in the anaerobic fermentation of lysine. (5S)-5-amino-3-oxohexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA + acetoacetate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K18013:kce; 3-keto-5-aminohexanoate cleavage enzyme [EC:2.3.1.247] 1.0 none 1.0 3343932 2631887 1916684 2486009 2001583 1878043 3314032 2782494 2610654 2346354 1561806 1658364 1819578 3810972 2795729 2009528 1932932 0 2904900 2445675 2477214 2444909 0 2708882 2726663 3003420 2545506 0 2696052 0 1803701 2039325 2154210 4071419 2900630 2577920 2914557 1878996 869188 329707 194305 698310 387146 377931 567044 871778 797724 630642 308875 338221 355211 548811 755006 144007 399720 0 835566 746731 512191 205054 0 346030 531726 707546 819734 0 882852 0 374767 483479 298823 867328 1009522 809753 1005690 530617 2529049 2240160 1997934 2016906 1198553 2088728 2222337 3111165 2423744 2972842 1188590 1702822 2217238 2783227 2628831 1708238 3069332 0 3479622 2832737 2407310 2716158 0 1639235 2678026 2815347 1771652 0 2579897 0 1557475 1349766 2359609 3097759 2654923 2345622 2812550 1435769 1759133 1679402 1700095 1586996 1082993 1879760 1647116 2526597 1725645 1986072 1254033 1500526 1037230 1344859 2198615 796640 1415403 0 1314636 1177099 593614 1244598 0 1787628 0 1559912 1330762 0 3056554 0 1566503 2179501 2289603 2361322 1776982 1384446 1974452 1132904 0 0 254558 186548 295294 1317104 716886 0 0 629291 45027 0 318590 0 890108 629765 0 0 0 0 635396 736546 0 932125 858186 0 199572 0 0 0 0 0 642550 139986 1488591 1876174 0 0 +AASN(Deamidated)GELVEK MGYG000000099_02236 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG3246@1|root,COG3246@2|Bacteria,1TQNV@1239|Firmicutes,248TX@186801|Clostridia,268HP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 S 1.0 beta-keto acid cleavage enzyme 1.0 kce 1.0 - 1.0 2.3.1.247 1.0 ko:K18013 1.0 ko00310,map00310 1.0 - 1.0 R10564 1.0 RC02728,RC03199 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 BKACE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_02236 1.0 3-keto-5-aminohexanoate cleavage enzyme. - The enzyme, isolated from the bacteria Fusobacterium nucleatum and Cloacimonas acidaminovorans, is involved in the anaerobic fermentation of lysine. (5S)-5-amino-3-oxohexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA + acetoacetate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K18013:kce; 3-keto-5-aminohexanoate cleavage enzyme [EC:2.3.1.247] 1.0 none 1.0 0 0 0 295496 0 0 383999 222014 0 420020 0 0 0 0 0 0 0 0 0 0 0 0 0 109536 216460 269914 0 0 0 0 0 0 376330 208854 0 0 0 0 1988205 0 1875860 1667723 0 1707305 1631202 2703989 2038055 2342912 0 1531193 0 0 0 1142468 0 0 0 1654214 0 1255715 0 1371811 1355455 2180789 2071643 0 0 0 0 0 1851869 2123271 2278579 1966566 2038799 1688986 466177 0 0 212760 0 0 0 0 0 0 0 0 0 0 0 213956 0 0 0 160823 0 312295 0 0 288647 0 0 0 0 0 0 0 0 0 0 587329 0 673657 332944 0 0 0 0 374830 365406 0 274975 0 0 539506 0 0 0 218091 0 0 0 471456 0 0 0 0 600346 395559 294010 0 0 0 0 0 551747 0 874604 0 415615 625773 0 0 0 247913 0 202858 99505 292221 0 212654 0 0 0 0 0 148088 0 0 0 142661 0 91155 0 241783 0 218580 0 0 0 0 0 0 336131 231466 90317 0 0 0 +AASN(Methyl[N](Asn->Gln)ESFGYNTDEIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.16666666666666666 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 723664 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNC(Carbamidomethyl)ELAFDNVIVPEENR MGYG000004642_01567 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__UMGS1670|s__UMGS1670 sp900548595|m__MGYG000004642 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004642_01567 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 391023 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 392333 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 693672 0 729616 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNC(Carbamidomethyl)EVIYENVK MGYG000000177_01043 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000177_01043 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 1093710 0 446631 982294 0 787098 0 0 839734 0 0 0 0 0 0 0 0 0 765689 0 815427 851273 0 583526 0 855300 1043942 0 975341 666475 0 0 730909 0 821457 0 0 375863 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 759464 0 646900 494975 0 0 0 0 438452 0 0 0 0 0 767456 0 0 0 776229 0 359325 419794 0 377199 0 673137 771366 0 706976 644114 0 0 640870 0 844122 0 838496 557507 146408 0 661180 0 0 327353 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 344375 0 503215 0 0 0 0 0 0 0 0 623410 0 0 0 0 574623 473047 0 495840 436453 0 0 0 0 303896 0 0 0 0 0 614629 0 0 0 330987 0 0 0 0 0 0 270178 569784 0 494593 0 0 0 357834 0 455479 0 305116 0 +AASNC(Carbamidomethyl)EVIYENVKVPAENLLGK MGYG000000177_01043 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000177_01043 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 2263247 1827348 2214898 3352209 0 1495304 0 0 1815073 0 0 0 0 0 2373339 0 0 557735 2246823 2034212 2316626 2307910 645983 1458731 2820942 1946844 2172653 739187 2556440 2140570 0 0 1790743 0 2270187 0 2227432 1640789 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550173 0 0 0 0 752793 0 0 0 0 660550 0 0 0 0 0 0 0 0 0 555263 1979814 1600731 1623515 1309874 0 847141 0 0 1369118 0 0 0 0 0 2397641 0 0 529959 2083630 2435318 952103 1569569 558641 902086 1675353 2326238 2185034 305442 2134350 1428688 0 0 0 0 2184180 0 1588266 1518895 567033 224940 700252 327188 0 242610 0 0 260371 0 0 0 0 0 478039 0 0 130520 402120 338784 371984 464883 0 454865 477889 349726 224082 0 173792 218398 0 0 1092218 0 462914 0 430109 552060 442070 582268 343382 291523 0 503972 0 0 264479 0 0 0 0 0 353109 0 0 0 543046 344854 418640 689366 0 817247 582335 696601 608877 0 461732 381897 0 0 130009 0 263935 0 1462366 507527 +AASNC(Carbamidomethyl)EVIYENVKVPAENLLGKEGQGYK MGYG000000177_01043 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__Anaerotignum faecicola|m__MGYG000000177 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000177_01043 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNC(Carbamidomethyl)EVIYENVR(Arg->Ala)VPKENLLGK MGYG000002791_01146;MGYG000000016_02518 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002791_01146 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 1738437 0 0 0 0 2747286 0 0 0 0 0 0 2169551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2220826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1862141 0 0 0 1409351 0 0 984093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2295524 0 0 0 0 0 0 0 0 0 549102 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 368565 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNC(Carbamidomethyl)EVIYENVR(Arg->Lys) MGYG000002791_01146 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Anaerotignaceae|g__Anaerotignum|s__|m__MGYG000002791 1.0 COG1960@1|root,COG1960@2|Bacteria,1V0RE@1239|Firmicutes,24CP0@186801|Clostridia,36QZ0@31979|Clostridiaceae 1.0 186801|Clostridia 1.0 I 1.0 Acyl-CoA dehydrogenase, C-terminal domain 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 - 1.0 Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002791_01146 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 - 1.0 none 1.0 0 0 0 0 0 0 725734 960401 0 0 0 0 0 0 1195204 629614 0 0 0 903942 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1007698 983111 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 502694 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376107 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNE(Cation_Ca[II])SFGYNEDEIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02283 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 605608 0 0 0 0 0 471967 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573604 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1190333 1082504 0 0 0 0 0 +AASNE(Cation_Ca[II])SFGYNEDEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 377950 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 231731 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNE(Cation_Fe[II])SFGYNEDEIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02283 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1578028 0 0 1038678 0 0 0 0 0 797216 +AASNE(Cation_Fe[II])SFGYNEDEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 867460 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 985418 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNE(Glu->Asn)SFGYNEDQIVSSDIVGMR MGYG000001315_01699 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01699 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 3101860 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1378068 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4964734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2965841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNE(Glu->Gln)SFGYNTDEIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.16666666666666666 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 572903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNES(Deoxy[S](Ser->Ala)YGYNTDEIVSSDIVGMR MGYG000004740_01468 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eubacterium_I|s__Eubacterium_I sp900557275|m__MGYG000004740 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004740_01468 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNES(Ser->Asn)FGYNTDEIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.16666666666666666 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1868001 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 376759 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYN(Asn->Thr)TDEIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.16666666666666666 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740239 0 2994118 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3133873 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYN(Deamidated)EDEIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02283 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1111941 0 0 0 0 0 0 0 0 +AASNESFGYNDEQIVSSDI(Xle->Val)IGMR MGYG000000215_01375 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella stercorea|m__MGYG000000215 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000215_01375 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYNDEQIVSSDII(Xle->Val)GMR MGYG000000215_01375 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Prevotella|s__Prevotella stercorea|m__MGYG000000215 1.0 COG0057@1|root,COG0057@2|Bacteria,4NEMF@976|Bacteroidetes,2FMT7@200643|Bacteroidia 1.0 976|Bacteroidetes 1.0 G 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000215_01375 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1992645 0 0 0 0 0 0 783538 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 754339 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYNE(Cation_Ca[II])DEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 572151 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 314428 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYNE(Cation_Fe[II])DEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 180421 0 0 454671 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 276225 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 666680 0 0 94315 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYNE(Cation_Na)DEIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02283 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 315801 0 356868 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 309621 0 0 0 0 0 0 166303 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 159381 0 0 0 0 0 292287 0 0 0 0 0 0 0 0 2489485 0 3453956 0 0 0 1517826 1441479 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1908743 0 2304631 0 4319141 0 1923287 0 0 0 0 1861868 0 0 +AASNESFGYNE(Cation_Na)DEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 941666 891337 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1265618 1030485 0 0 0 0 0 0 0 0 0 0 0 652741 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3062377 1491923 351197 0 778960 0 0 0 0 2115160 0 0 0 0 0 0 0 0 0 0 0 0 0 919260 0 0 0 0 0 0 0 0 0 0 0 0 640557 0 0 0 0 0 0 0 0 0 0 0 1327497 0 0 0 0 0 0 0 842686 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1942808 0 2599191 0 955473 0 0 0 0 1428293 0 3028204 0 0 0 0 0 0 0 0 0 0 0 352094 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1336207 0 0 651166 0 0 0 0 +AASNESFGYNE(Cation_Na)DQIVSSDIVGMR MGYG000001315_01699 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01699 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYNE(Glu->Gln)DEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1301321 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYNED(Asp->Asn)EIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 2823666 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1395539 0 0 1737976 1336698 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 409964 0 0 0 0 0 0 606428 0 0 0 0 0 0 0 0 0 0 423725 0 0 0 0 0 0 0 0 0 0 987983 0 0 0 0 0 0 0 0 788982 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1508985 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYNED(Cation_Ca[II])EIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02283 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 250120 289580 0 99916 0 0 0 0 0 176997 142006 0 0 0 0 129912 153171 0 0 0 0 0 0 0 0 64264 0 0 0 0 0 0 0 0 0 0 206305 0 235104 237592 0 211349 0 0 154958 0 0 0 213198 0 0 0 0 173313 91200 0 0 0 0 0 0 0 0 257600 0 0 0 0 0 0 0 0 0 0 262841 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 207813 392258 0 276696 0 0 92899 0 0 162791 230540 0 0 0 0 232274 346027 0 0 0 0 0 0 0 0 632381 0 0 0 0 0 0 0 0 0 0 178574 0 1013619 947213 0 1439687 0 0 946582 0 0 1158204 749416 0 0 0 0 798062 836648 0 0 0 0 0 0 0 0 714180 0 0 1599452 0 0 0 0 0 0 0 108400 0 +AASNESFGYNED(Cation_Ca[II])EIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 720726 659218 0 0 785011 0 0 0 492292 928928 517459 482411 0 301367 398129 0 0 0 0 0 590190 0 291494 0 0 0 0 625394 689109 474087 655068 355069 0 0 0 0 602892 0 917152 191124 0 0 70189 0 0 0 123349 338410 76363 209528 0 76773 70102 0 0 0 0 0 156942 0 196876 0 0 0 0 626684 333689 949740 466902 88290 0 0 0 0 157479 0 0 441029 0 0 140983 0 0 0 376979 221221 608180 312581 0 383992 333073 0 0 0 0 0 1042588 0 169301 0 0 0 0 416461 330181 386763 1306513 534923 0 0 0 0 401457 0 1082557 428350 0 0 298033 0 0 0 318820 457661 184650 543508 0 128590 392817 0 0 0 0 0 441198 0 312182 0 0 0 0 828697 404231 1006713 673933 382906 0 0 0 0 529868 0 0 556434 0 0 201375 0 0 0 107789 238396 158728 160071 0 129239 261488 0 0 0 0 0 102021 0 83387 0 0 0 0 173142 0 492587 0 511179 0 0 0 0 379814 +AASNESFGYNED(Cation_Fe[II])EIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02283 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 956989 0 0 0 0 0 0 0 0 0 0 0 0 0 617435 0 0 0 0 1102060 0 0 0 0 0 0 0 0 0 0 0 0 943809 0 0 0 0 +AASNESFGYNED(Cation_Fe[II])EIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 682615 673910 0 0 672581 0 648023 0 0 925480 0 0 0 0 0 0 0 0 0 361129 511923 0 263716 0 0 0 0 698559 0 412263 0 409597 0 0 0 0 569695 0 795079 88899 0 281268 134330 0 145754 0 0 192814 0 0 0 0 0 0 0 0 0 131814 0 0 247999 0 0 0 0 368249 0 0 387701 91704 0 0 0 0 117281 0 307940 89178 0 97763 202980 0 325386 0 0 263644 0 0 0 0 0 0 0 0 0 139048 401195 0 207482 0 0 0 0 250949 0 353067 908793 498679 0 0 0 0 277842 0 0 272934 0 464806 159596 0 112896 0 0 191764 0 0 0 0 0 0 0 0 0 257740 77627 0 264047 0 0 0 0 664204 0 950802 543319 139104 0 0 0 0 283763 0 0 378104 0 189395 52519 0 176608 0 0 78706 0 0 0 0 0 0 0 0 0 47476 156704 0 0 0 0 0 0 111311 0 302371 644227 248480 0 0 0 0 95595 +AASNESFGYNED(Cation_Mg[II])EIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYNED(Cation_Na)EIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02283 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 564841 0 0 0 0 0 0 0 0 0 0 0 0 2590738 0 2116931 0 0 1163280 0 0 0 0 0 0 0 0 2672997 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2795063 0 0 0 0 +AASNESFGYNED(Cation_Na)EIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 1013275 2103945 2029953 0 1574009 1870141 0 1403476 0 1321870 2688175 1600710 1299919 0 0 1113685 1233222 1174098 919712 828315 1056839 1669700 921165 792900 1010712 0 927946 1941294 2021903 1888199 1490259 2086535 0 0 1027353 721729 1107494 1717795 528028 2443362 403230 0 1130278 436058 0 0 0 303795 940749 377166 818362 283173 469451 313524 310488 1610846 409007 579045 470636 288448 687902 886273 549704 700906 827039 1243710 1247179 818757 0 0 312941 848039 0 594029 552853 506958 784907 0 712636 0 430035 807524 0 931093 0 772546 740843 1072073 780066 736091 829051 0 1177763 399440 752733 728937 752153 1429255 531865 715532 772142 858008 865691 846509 0 809227 1146931 2441412 1527887 932349 1144653 700353 667437 983267 359535 3461535 0 0 1613113 632523 0 397244 0 0 0 613682 1196427 375327 323974 740747 824377 431003 390527 504703 818317 879831 0 795336 349659 387723 520819 540103 0 435253 0 2021809 0 152617 281121 306347 268997 0 335136 0 1167616 0 505557 403849 0 198231 0 259654 743775 400045 595311 424646 319622 638413 301129 224638 344527 184916 232283 380414 501726 218740 240235 137441 212143 656014 342869 237461 0 1957853 0 130419 0 166681 72439 848750 +AASNESFGYNED(Cation_Na)QIVSSDIVGMR MGYG000001315_01699 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01699 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 456130 698208 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 436040 0 0 0 0 0 368138 0 0 0 0 0 0 0 566512 0 0 313942 0 641161 797079 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1169221 0 0 0 0 0 633317 0 0 0 0 0 0 0 809206 0 0 354302 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 316119 0 0 0 0 0 0 0 0 0 0 0 0 0 421276 0 0 0 0 361746 478646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 406503 0 0 0 0 0 255262 0 0 0 0 0 0 0 106794 0 0 0 0 229206 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 219875 0 0 0 0 0 0 0 314828 0 0 0 0 +AASNESFGYNEDE(Cation_Na)IVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726514 0 0 0 0 0 0 0 0 0 0 226661 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 438723 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 989318 0 0 0 0 0 0 0 0 0 0 0 0 285075 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1785707 0 0 0 0 0 +AASNESFGYNEDE(Glu->Gln)IVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 1804009 0 0 0 0 0 0 3543488 0 0 0 0 0 1296476 1565600 0 1376302 0 0 0 1508507 0 0 0 0 0 0 0 0 0 0 0 0 0 2270541 1211655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 881826 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 421062 0 0 570110 0 0 0 0 0 0 0 565788 0 0 0 0 0 0 0 0 0 0 589645 515504 0 1026733 0 0 0 0 0 0 0 0 0 0 0 0 961865 0 0 975834 0 1591285 2160632 0 0 0 0 954972 0 0 0 0 0 0 0 0 0 0 0 426938 0 449793 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1025894 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYNEDEIVSSDIVGM(Oxidation)K MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02283 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 224960 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1147060 1292254 1169403 1930402 0 796120 1723908 829366 663618 1473903 2188085 917833 1481455 3129280 1157175 914606 923774 0 1137123 0 1921543 1190030 0 963411 1665125 939683 1894674 0 1967618 0 848719 1407724 2430709 1399018 1322597 1495349 1184681 1050322 +AASNESFGYNEDEIVSSDIVGM(Oxidation)R MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 575879 1088398 1243576 0 1195127 1161066 0 0 441591 387468 1453016 933396 0 439318 521630 1594801 1637884 2462752 388710 396064 0 2025014 643261 689038 656954 403862 0 565001 953009 0 676781 1247990 711146 0 0 0 242581 800201 266875 1102429 208849 0 509263 323255 0 0 623390 324083 432543 0 0 0 193499 206793 0 851867 110302 317676 0 0 392355 259138 0 179801 0 500900 622600 0 2078062 948021 0 0 0 0 229315 167814 397101 3937466 621312 0 221998 675834 0 0 427373 599279 276421 761868 0 550058 597886 573924 786023 0 366157 682165 0 1098462 334205 598057 632229 902665 0 404454 443794 0 547527 2126818 1100261 0 0 0 437175 681149 0 1637901 624500 0 1061444 365601 0 0 337374 359521 866189 397406 0 381368 186577 491673 611613 244067 149811 313068 0 552916 406167 682646 313760 328873 0 886283 1211711 0 1430245 1223391 760810 0 0 0 169488 879676 192425 2011558 555285 0 354955 214935 0 0 0 153734 551349 203442 0 373797 332986 388989 0 278781 0 0 0 357221 481383 220078 214334 0 0 605773 369959 0 711556 1373315 1157461 0 0 0 160080 508244 +AASNESFGYNEDEIVSSDIVGMK MGYG000000133_02283 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A|s__Blautia_A caecimuris|m__MGYG000000133 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000133_02283 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 134921 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10739095 9739351 9364914 16092352 973700 4856424 12612512 6334462 6148312 13587749 16727620 6380161 12755604 21220087 11957852 7523754 8288357 0 11215803 2336886 12791762 7826040 0 8215239 11973532 10623175 13796803 0 17337419 2125309 8670568 14234659 21056479 12671001 10404668 16299917 9227332 8513088 +AASNESFGYNEDEIVSSDIVGMR MGYG000000212_01474;MGYG000004785_01017;MGYG000000171_00850;MGYG000000002_02120;MGYG000003695_01114;MGYG000001338_02547;MGYG000003335_00316;MGYG000004296_01958;MGYG000002298_02410;MGYG000000213_00374;MGYG000000142_01979;MGYG000000263_01341;MGYG000000252_01324 family d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000212_01474 0.07692307692307693 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 3649604 8108166 9097159 2189600 7313039 9961200 1613892 5552081 3858987 4901433 11739331 5620271 5139967 3258686 3405323 4287847 5802453 6157200 3880905 3342438 3858565 6020263 4547901 3371932 3593972 2813446 3527767 6889237 7283613 7343083 5896832 9081930 4607723 3272677 3317447 2688156 2721017 5867586 1975547 9802594 1162758 2189055 4549277 1804334 3212294 2314556 1411727 1084792 3783625 1324602 2194348 1186473 1482175 1177390 1513646 7175514 1330537 2442705 2252367 1104769 2636528 3431505 1480430 2355566 2739802 4742368 5422246 3021389 15231390 6907737 1747058 2523186 2488224 2332295 1706148 1649229 2219974 10880589 2967242 2112130 1656678 2880310 1791390 3058135 1616943 2918965 2340007 3709464 3072624 2276946 2867024 3451611 3800083 780539 2845993 2335628 3048293 5311276 1607759 2070377 2924967 3632830 2993036 2225487 2277999 2787244 4563698 8056485 4998597 3764309 3838936 2088876 2350191 3201465 1556510 13259763 5114874 1699788 6326962 2471133 1859110 1811477 1756149 2321245 3259443 2089223 4113198 1588200 1440012 3340602 2626883 1472219 1329118 2290623 2731078 2943185 888375 2796364 1545418 1481087 2075238 2864227 7815965 3234479 10476089 6903015 3913127 663182 2023876 1483301 1265727 6112894 1260098 9362730 3912185 959040 1574100 1126472 1385550 1246029 706217 1087901 4203598 1197075 2837495 1843723 1015233 2222073 868792 880951 833166 478486 917913 1216977 1822553 1431521 1317689 927403 2074862 2557361 1217690 857410 4325405 5765613 10472181 2429429 14367651 2601912 1131615 3870965 +AASNESFGYNEDQIVSSDIVGM(Oxidation)R MGYG000001315_01699 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01699 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 531646 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 308554 0 0 0 0 642788 0 0 226524 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 236826 0 0 0 0 282846 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 268584 0 0 0 0 0 0 0 869959 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 724503 0 0 0 0 939041 0 0 446548 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 492199 0 0 0 0 430802 +AASNESFGYNEDQIVSSDIVGMR MGYG000001315_01699 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Bariatricus|s__Bariatricus comes|m__MGYG000001315 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001315_01699 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 518386 2190326 3414297 1216718 0 0 788928 0 0 2002320 3685180 0 0 0 0 0 879302 0 2097031 0 0 0 0 0 0 0 0 0 860036 0 0 1638001 1929883 0 0 0 1383037 2733164 1955066 2556329 2385270 2887698 1809188 1927844 2866261 3052826 1374335 1758328 1161636 1330819 2753812 1628661 2132286 1228148 0 0 2299674 4624926 1924887 1018704 0 2931840 2673948 2118955 2144203 0 2571424 1539090 3133014 3485149 1686351 1879408 2124858 2126226 1599215 2400074 392165 725113 482778 537506 451131 582061 575379 614629 519685 650260 612872 1026681 560421 691496 654431 1082248 712171 0 576786 703934 791239 539991 0 278826 665257 983975 666751 0 756020 709257 527635 736667 1349192 596578 775544 722012 319661 685343 0 1574436 3074226 1117776 1378095 1318191 0 0 732318 1088145 0 2611798 1897513 1195350 831965 2558208 1515605 0 0 0 1214249 0 0 0 0 975653 1523199 0 0 1098118 1993300 1477520 3473213 572026 0 0 721728 3078554 1012560 680913 2619382 1015841 635699 534880 1167909 1072347 714183 953972 1078561 730056 1680033 1611004 1225557 1334876 1091089 0 1374423 675417 0 719016 0 426262 1348175 796008 1263534 0 1445332 441462 1134437 925814 3350849 1098762 1672292 1192332 1183186 3049237 +AASNESFGYNTD(Cation_Na)EIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.16666666666666666 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 521778 0 0 0 0 0 0 0 402088 0 0 0 0 0 0 0 318484 697237 0 0 0 0 624283 0 0 234876 0 942163 0 0 0 0 0 456739 609540 246804 379061 0 516052 0 0 0 0 0 0 0 656726 0 0 0 0 0 0 0 1399872 741200 0 0 0 0 452358 0 0 742388 0 669753 0 0 0 0 0 768623 842424 682668 0 0 566084 0 0 0 0 0 0 0 183285 0 0 0 0 0 0 0 319670 1535899 0 0 0 0 0 0 0 429277 0 469170 0 0 0 0 0 228417 425885 0 315434 0 297117 0 0 0 0 0 0 0 287979 0 0 0 0 0 0 0 710079 56619 0 0 0 0 0 0 0 345633 0 171308 0 0 0 0 0 335124 207039 200678 145903 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1227143 0 0 0 0 +AASNESFGYNTDE(Cation_Na)IVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.16666666666666666 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 627471 0 0 0 0 0 0 0 0 0 591642 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYNTDEIVSSDIVGM(Oxidation)R MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.16666666666666666 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 251481 0 0 313039 0 527628 349853 0 0 0 0 0 0 0 364755 1141497 0 0 0 370336 720970 233067 0 0 0 761519 0 0 0 0 195378 243717 0 0 0 166156 0 0 253005 0 0 389220 0 411127 715294 0 0 0 0 0 0 0 685959 584631 0 0 0 293723 249490 316957 0 0 0 365573 0 0 0 0 287205 407937 0 0 0 676728 0 0 197144 0 0 209317 0 461506 344574 0 0 0 0 0 0 0 508608 357970 0 0 0 224061 583446 263164 0 0 0 344390 0 0 0 0 261915 337693 0 0 0 0 0 0 399884 0 0 317974 0 404483 308651 0 0 0 0 0 0 0 635170 216887 0 0 0 273620 0 374178 0 0 0 423420 0 0 0 0 430959 492749 0 0 0 416959 0 0 525745 0 0 688527 0 268658 0 0 0 0 0 0 0 0 0 0 0 0 0 547437 347746 796161 0 0 0 204661 0 0 0 0 798557 309669 0 0 0 522209 +AASNESFGYNTDEIVSSDIVGMR MGYG000000205_02269;MGYG000001319_00348;MGYG000000495_01130;MGYG000000233_00345;MGYG000003702_00925;MGYG000004707_01697 class d__Bacteria|p__Firmicutes_A|c__Clostridia 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 0.5 186801|Clostridia 1.0 C 0.5 Psort location Cytoplasmic, score 0.5 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000205_02269 0.16666666666666666 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 1266399 1086991 1369616 1344694 1052721 1102408 1164779 2016625 1521340 1577632 1723775 1412506 1105730 1289365 1351404 890591 984016 2579654 1291258 1159000 946543 993897 2461717 935368 1446413 1140985 1085202 3251832 1472724 1773567 1260798 1115407 787684 1420811 1704113 1039660 1147805 922230 1893917 2034501 1692717 2504317 2728288 1421110 3314368 2440361 1399349 1940067 1900920 2109041 3088723 2207259 2377529 3009472 5463975 2828828 2000101 2338821 1882416 1042614 1666795 1387833 2228783 2053996 2161642 2274452 2739765 2018144 2066594 2655907 2006419 2270824 2312326 1955543 2057422 1750916 1632746 1256167 1067532 689595 898641 631439 1249103 1789358 1316175 0 931704 1229096 0 1511128 1864729 1215341 1507739 621946 1489372 1482579 1196597 954706 1498565 822104 1591938 1636223 1614809 1777789 1251674 1650504 1254616 984186 1577654 2090710 1506515 1120111 1668270 958263 995423 1134868 1258192 1201508 919126 1019980 1377280 1437869 1105766 1432551 860794 803327 1106162 889929 871966 1137338 2515006 472303 1144677 992410 2274073 1162079 3021653 7551032 1091823 966620 1138167 984551 903724 695107 995252 1179232 1755606 2111907 3613152 1970482 2258384 1538163 2711071 5394511 8012371 23060521 0 9579666 4602235 2038524 1766342 4608953 372210 824528 11861389 16018923 371070 5598551 8626821 1264839 352101 2564820 8138908 1857452 6538920 19288432 1057885 284965 2813815 0 18015063 0 413106 1130049 1438084 2976712 16522118 246058 649842 20297496 +AASNESFGYNTDQIVSSDIVGMR MGYG000000249_01352 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Mediterraneibacter|s__Mediterraneibacter faecis|m__MGYG000000249 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000249_01352 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 573790 0 0 0 0 0 0 0 0 0 392592 0 0 0 0 0 0 0 0 0 0 0 0 279093 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136377 0 0 0 0 0 0 0 0 0 0 0 0 677012 0 0 0 0 0 0 0 0 0 0 0 0 750156 0 0 0 0 0 0 1065781 0 0 0 0 1003924 0 0 639083 0 896087 0 0 0 0 806330 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 170173 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESFGYNTEEIVSSDVIGMR MGYG000003582_01256 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__CAG-272|g__Firm-07|s__Firm-07 sp900770145|m__MGYG000003582 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000003582_01256 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 431919 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 660057 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNESY(Tyr->Phe)GYNTDEIVSSDIVGMR MGYG000004740_01468 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Eubacterium_I|s__Eubacterium_I sp900557275|m__MGYG000004740 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004740_01468 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASNEVIKK MGYG000000271_02066 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Roseburia|s__Roseburia sp900552665|m__MGYG000000271 1.0 COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,27IMH@186928|unclassified Lachnospiraceae 1.0 186801|Clostridia 1.0 G 1.0 Fibronectin type III-like domain 1.0 - 1.0 - 1.0 3.2.1.21 1.0 ko:K05349 1.0 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 1.0 - 1.0 R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040 1.0 RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 GH3 1.0 - 1.0 Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C 1.0 - 1.0 GH3 1.0 GH3 1.0 GH3 1.0 MGYG000000271_02066 1.0 beta-glucosidase. gentobiase. Wide specificity for beta-D-glucosides.-!-Some examples also hydrolyze one or more of the following: beta-D- galactosides, alpha-L-arabinosides, beta-D-xylosides and beta-D- fucosides. Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose. 1.0 1.0 1.0 1.0 Cyanoamino acid metabolism|Starch and sucrose metabolism|Phenylpropanoid biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K05349:bglX; beta-glucosidase [EC:3.2.1.21] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 156831 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 136098 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1400441 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394137 0 0 0 0 0 0 0 0 +AASNGELVAK MGYG000002926_00667;MGYG000002156_01167;MGYG000001824_00563;MGYG000002143_01899;MGYG000002720_00858;MGYG000002794_00766;MGYG000004487_00300 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__CAG-83 1.0 COG3246@1|root,COG3246@2|Bacteria,4NGNQ@976|Bacteroidetes,2FQZR@200643|Bacteroidia,22WVP@171551|Porphyromonadaceae 0.8571428571428571 976|Bacteroidetes 0.8571428571428571 S 1.0 3-keto-5-aminohexanoate cleavage protein 0.8571428571428571 - 0.8571428571428571 - 1.0 2.3.1.247 1.0 ko:K18013 1.0 ko00310,map00310 1.0 - 1.0 R10564 1.0 RC02728,RC03199 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 BKACE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002926_00667 0.14285714285714285 3-keto-5-aminohexanoate cleavage enzyme. - The enzyme, isolated from the bacteria Fusobacterium nucleatum and Cloacimonas acidaminovorans, is involved in the anaerobic fermentation of lysine. (5S)-5-amino-3-oxohexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA + acetoacetate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K18013:kce; 3-keto-5-aminohexanoate cleavage enzyme [EC:2.3.1.247] 1.0 none 1.0 3266745 1855448 2322448 3723424 1738652 2058161 5023882 2758521 3602271 2478046 2305859 2335478 1722883 3610123 2883249 1740721 2412130 2311382 2034724 2166718 2514829 3049399 3107991 3893437 3431908 3587908 2901104 2514061 3694874 1576980 2652582 1827162 2193271 4009707 3907564 3758426 4538230 2545696 903317 610713 626187 1299456 655895 756956 1114757 1175895 1134582 1104573 738031 471445 640815 1049773 961801 550674 941574 1940351 1379184 1285603 795007 702746 3042419 599516 919193 1016130 1146318 2557731 738613 769668 0 795030 609630 1028148 1284720 872751 1031220 659665 3146134 2118988 2855264 3369166 2705511 4014583 3828908 4653686 4587505 3763625 2695902 3359269 2692088 4786729 3555553 2909324 4312135 8763713 3698848 3557653 3272971 3590144 5988710 4188568 4535857 4473369 3621277 5246145 4093588 3902264 3803558 3022338 3633456 4213658 4223384 4970667 3166080 3209121 1538856 1345911 1528170 1109283 1161046 1139728 1320765 1428672 1186023 1688229 961883 1466480 835504 976955 2006374 622496 1001964 2045955 1497185 859866 545112 1241273 1036318 1488059 1316960 1288090 1124690 1326532 1765343 1400508 1422249 1303571 1794794 1761900 1494791 1184250 1293571 1166236 619867 257683 287151 0 0 532570 396556 368638 325788 671978 0 851080 225174 414550 261686 585711 300655 843648 244675 0 0 229102 1036523 297146 294164 549158 0 722822 322067 524720 0 264408 0 503335 546224 907910 0 0 +AASNGELVEK MGYG000000099_02236 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Oscillospiraceae|g__Flavonifractor|s__Flavonifractor plautii|m__MGYG000000099 1.0 COG3246@1|root,COG3246@2|Bacteria,1TQNV@1239|Firmicutes,248TX@186801|Clostridia,268HP@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 S 1.0 beta-keto acid cleavage enzyme 1.0 kce 1.0 - 1.0 2.3.1.247 1.0 ko:K18013 1.0 ko00310,map00310 1.0 - 1.0 R10564 1.0 RC02728,RC03199 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 BKACE 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000099_02236 1.0 3-keto-5-aminohexanoate cleavage enzyme. - The enzyme, isolated from the bacteria Fusobacterium nucleatum and Cloacimonas acidaminovorans, is involved in the anaerobic fermentation of lysine. (5S)-5-amino-3-oxohexanoate + acetyl-CoA = (3S)-3-aminobutanoyl-CoA + acetoacetate. 1.0 1.0 1.0 1.0 Lysine degradation 1.0 K18013:kce; 3-keto-5-aminohexanoate cleavage enzyme [EC:2.3.1.247] 1.0 none 1.0 0 0 516143 320640 0 0 546795 0 375930 0 0 0 0 0 517616 0 0 0 0 210520 0 0 0 0 0 306199 0 0 0 0 0 0 0 0 0 0 297577 490297 2968025 0 1214130 2464090 1373153 0 2292919 1975019 2950588 2249088 1676051 1603385 0 1786939 1738708 1011547 1639347 0 1776552 2015204 0 0 0 0 1447763 1922037 2142738 0 0 0 0 0 1401391 0 0 2466960 1980028 1052614 0 0 0 105776 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 141696 0 933748 810304 582297 0 638383 0 502726 550776 335320 808478 0 474953 0 733666 541041 0 466449 329068 0 0 0 0 370787 0 0 0 0 0 0 0 637425 0 0 0 0 830996 214596 0 0 0 0 0 0 315540 0 0 0 226024 0 0 0 279094 0 0 215853 222892 0 0 0 0 0 0 226805 0 0 0 0 0 0 0 0 227847 0 0 +AASNTNAYYSVSK MGYG000000089_02197 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__CAG-353|s__CAG-353 sp900066885|m__MGYG000000089 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 not_found 1.0 MGYG000000089_02197 1.0 - - - - 1.0 1.0 1.0 1.0 not_found 1.0 - 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1578044 0 0 0 0 1787279 0 0 0 0 1248211 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 239895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASPAAEIMEK MGYG000000243_00038 genome d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae|g__Phocaeicola|s__Phocaeicola massiliensis|m__MGYG000000243 1.0 COG0702@1|root,COG0702@2|Bacteria,4NEPE@976|Bacteroidetes,2FMBU@200643|Bacteroidia,4ANN0@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 GM 1.0 SusD family 1.0 - 1.0 - 1.0 - 1.0 ko:K21572 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko02000 1.0 8.A.46.1,8.A.46.3 1.0 - 1.0 - 1.0 SusD-like_3,SusD_RagB 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000243_00038 1.0 - - - - 1.0 1.0 1.0 1.0 - 1.0 K21572:susD; starch-binding outer membrane protein, SusD/RagB family 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASPVELTTIK MGYG000002485_01479 genome d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A|s__Fusobacterium_A mortiferum|m__MGYG000002485 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,378RN@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000002485_01479 1.0 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1469446 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASPVELTTIKPVGK MGYG000004893_00001;MGYG000002485_01479 genus d__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Fusobacteriaceae|g__Fusobacterium_A 1.0 COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1143@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1143@2|Bacteria,378RN@32066|Fusobacteria 1.0 32066|Fusobacteria 1.0 C 1.0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin 1.0 nifJ 1.0 - 1.0 1.2.7.1 1.0 ko:K03737 1.0 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 1.0 M00173,M00307 1.0 R01196,R10866 1.0 RC00004,RC02742 1.0 br01601,ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C 1.0 - 1.0 - 1.0 - 1.0 GT2 1.0 MGYG000004893_00001 0.5 pyruvate synthase. pyruvic-ferredoxin oxidoreductase. The enzyme also decarboxylates 2-oxobutanoate with lower efficiency, but shows no activity with 2-oxoglutarate.-!-This enzyme is a member of the 2-oxoacid oxidoreductases, a family of enzymes that oxidatively decarboxylate different 2-oxoacids to form their CoA derivatives, and are differentiated based on their substrate specificity.-!-For examples of other members of this family, see EC 1.2.7.3 and EC 1.2.7.7. CoA + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate = acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Citrate cycle (TCA cycle)|Pyruvate metabolism|Butanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K03737:por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 5479851 3690785 10478133 1446195 5038003 11237081 7115549 5319452 6505238 15140779 9442592 5782792 9087455 6625182 4687468 12603980 9327403 0 4809831 4068168 4811181 14741327 0 11510724 4145286 4863242 5766914 0 3898234 6462751 8290906 3438562 11420256 5207446 6684664 5909400 5352127 9973157 128044 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASQFEALR MGYG000002478_00339;MGYG000004797_04223;MGYG000001378_04186;MGYG000000236_01414 family d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales|f__Bacteroidaceae 1.0 COG1884@1|root,COG1884@2|Bacteria,4NDVE@976|Bacteroidetes,2FM0R@200643|Bacteroidia,4AMKH@815|Bacteroidaceae 1.0 976|Bacteroidetes 1.0 I 1.0 methylmalonyl-CoA mutase small subunit 1.0 mutA 1.0 - 1.0 5.4.99.2 1.0 ko:K01847 1.0 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 1.0 M00373,M00376,M00741 1.0 R00833 1.0 RC00395 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 MM_CoA_mutase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002478_00339 0.25 methylmalonyl-CoA mutase. methylmalonyl coenzyme A mutase. - (R)-methylmalonyl-CoA = succinyl-CoA. 1.0 1.0 1.0 1.0 Valine, leucine and isoleucine degradation|Glyoxylate and dicarboxylate metabolism|Propanoate metabolism|Carbon fixation pathways in prokaryotes|Metabolic pathways|Microbial metabolism in diverse environments|Carbon metabolism 1.0 K01847:MUT; methylmalonyl-CoA mutase [EC:5.4.99.2] 1.0 none 1.0 2667029 2248554 2088400 2827831 3275735 2973820 2945973 1593511 2402842 2110032 2080518 0 2434745 2847499 1977054 3421168 3346200 671588 0 2787650 2842675 2505717 995340 3801104 1838980 2406831 3087296 1055792 3145399 2759089 3139071 3550566 2667285 968994 3130372 3203929 2681839 2472050 1917704 217372 0 1815864 1713012 223079 0 1855570 1120306 198518 0 0 1086004 1391023 1506678 0 0 450525 799828 1630765 1303065 0 473173 0 1003588 1163608 128863 482049 1398161 729075 0 1371861 0 932139 2218391 606741 1660587 0 2234062 1292045 2699742 2480828 2591443 3058178 2460446 1929445 2670954 2485389 2008750 0 1887824 2196230 2361709 2210564 1776230 1995507 2271687 2153983 1857995 1913159 1931885 2771578 1974416 1792447 2125823 556189 1946227 1876370 3254607 1560630 2119257 808573 2406300 2494952 2076576 2245904 5178645 5270823 0 0 320982 398208 4129484 983400 1024736 0 921765 0 0 873983 245031 789447 0 0 0 291635 198953 1461748 0 578652 740495 363508 818062 0 417100 0 0 6943860 0 7197034 1060854 5771189 5277170 3390448 2320848 1432177 1557975 2122557 3622505 2273496 2207344 2386929 2262826 1131199 920376 0 2318310 491336 1857884 2325040 400051 1464739 2809808 3294032 1632438 2128931 1830556 2050211 1718752 991003 1889060 1275971 2324586 3092003 1906260 1862010 959229 2641315 2213346 1666824 2283795 2081434 +AASQSIIPVDTK MGYG000002494_04272 genome d__Bacteria|p__Proteobacteria|c__Gammaproteobacteria|o__Enterobacterales|f__Enterobacteriaceae|g__Citrobacter_B|s__Citrobacter_B koseri|m__MGYG000002494 1.0 COG0057@1|root,COG0057@2|Bacteria,1MU93@1224|Proteobacteria,1RMBM@1236|Gammaproteobacteria,3WX4Q@544|Citrobacter 1.0 1236|Gammaproteobacteria 1.0 G 1.0 Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate 1.0 epd 1.0 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019318,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043891,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048001,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.0 1.2.1.12,1.2.1.72 1.0 ko:K00134,ko:K03472 1.0 ko00010,ko00710,ko00750,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map00750,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00124,M00165,M00166,M00308,M00552 1.0 R01061,R01825 1.0 RC00149,RC00242 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 iYL1228.KPN_03356 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002494_04272 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). | erythrose-4-phosphate dehydrogenase. triosephosphate dehydrogenase. | erythrose 4-phosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. | Was originally thought to be an EC 1.2.1.12, but this has since been disproved, as glyceraldehyde 3-phosphate is not a substrate.-!-Forms part of the pyridoxal-5'-phosphate cofactor biosynthesis pathway in Escherichia coli, along with EC 1.1.1.290, EC 2.6.1.52, EC 1.1.1.262, EC 2.6.99.2 and EC 1.4.3.5. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. | D-erythrose 4-phosphate + H2O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Vitamin B6 metabolism|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]|K03472:epd; D-erythrose 4-phosphate dehydrogenase [EC:1.2.1.72] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1106825 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASQVMR MGYG000002528_01838;MGYG000000028_01623 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Anaerostipes 1.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,268VG@186813|unclassified Clostridiales 1.0 186801|Clostridia 1.0 J 1.0 Involved in the binding of tRNA to the ribosomes 1.0 rpsJ 1.0 - 1.0 - 1.0 ko:K02946 1.0 ko03010,map03010 1.0 M00178,M00179 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S10 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002528_01838 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02946:RP-S10, MRPS10, rpsJ; small subunit ribosomal protein S10 1.0 none 1.0 0 0 0 0 0 169105 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317416 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 577734 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 394410 0 664528 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1004572 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 3153166 0 2038876 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASS(Methyl[S](Ser->Thr)ESFGYNEDQIVSSDVIGMR MGYG000002641_00563;MGYG000000195_01135 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002641_00563 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 965637 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 997531 0 0 0 0 0 0 0 0 0 0 1044268 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 520977 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 740312 0 0 0 0 0 0 0 0 0 0 1096555 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 528038 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASSESFGYNED(Asp->Asn)QIVSSDVIGMR MGYG000002641_00563;MGYG000000195_01135 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002641_00563 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 674895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASSESFGYNEDPIVSSDVIGMR MGYG000001157_00577 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__Gemmiger sp900540775|m__MGYG000001157 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000001157_00577 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 1202376 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASSESFGYNEDQIVSSDVIGMR MGYG000002641_00563;MGYG000000195_01135 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000002641_00563 0.5 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 447072 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 251382 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 411828 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASSESFGYTEEQLVSSDVIGMR MGYG000004732_01055 genome d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Gemmiger|s__|m__MGYG000004732 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3WGXW@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004732_01055 1.0 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 591895 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 532611 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 726083 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 321824 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASSHTGAIASSDSAVEALFR MGYG000004876_01301;MGYG000000224_00594;MGYG000002438_02772;MGYG000000098_00437;MGYG000002549_03206;MGYG000002561_00294;MGYG000001346_02091;MGYG000003681_02187;MGYG000003351_03484;MGYG000004848_00129;MGYG000000196_01926;MGYG000000236_03757 order d__Bacteria|p__Bacteroidota|c__Bacteroidia|o__Bacteroidales 1.0 COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,4NFTI@976|Bacteroidetes,2FNSJ@200643|Bacteroidia,4ANVS@815|Bacteroidaceae 0.8333333333333334 976|Bacteroidetes 1.0 C 1.0 CoA binding domain protein 0.9166666666666666 - 1.0 - 1.0 - 1.0 ko:K09181 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 ATP-grasp_5,CoA_binding_2,Succ_CoA_lig 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004876_01301 0.08333333333333333 - - - - 1.0 1.0 1.0 1.0 - 1.0 K09181:yfiQ; acetyltransferase 1.0 none 1.0 0 0 0 1359224 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2457551 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +AASSNTISSNVMGSVHYSSPEQVR MGYG000000184_01368;MGYG000000133_01144;MGYG000000301_01423 genus d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Lachnospirales|f__Lachnospiraceae|g__Blautia_A 1.0 COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3XZC8@572511|Blautia 1.0 186801|Clostridia 1.0 KLT 1.0 Psort location CytoplasmicMembrane, score 1.0 prkC 1.0 - 1.0 2.7.11.1 1.0 ko:K12132 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000,ko01000,ko01001 1.0 - 1.0 - 1.0 - 1.0 PASTA,PBP1_TM,Pkinase 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000184_01368 0.3333333333333333 non-specific serine/threonine protein kinase. threonine-specific protein kinase. This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.-!-Formerly EC 2.7.1.37 and EC 2.7.1.70. (1) ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]. (2) ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl- [protein]. 1.0 1.0 1.0 1.0 - 1.0 K12132:prkC, stkP; eukaryotic-like serine/threonine-protein kinase [EC:2.7.11.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 317774 714241 0 0 0 0 0 590276 670939 0 0 746994 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 978367 0 0 606918 0 300868 +AAST(Thr->Asn)ESFGYNTDEIVSSDIVGMR MGYG000000038_02185;MGYG000001602_01805;MGYG000002279_00557;MGYG000001008_00728 domain d__Bacteria 1.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia 1.0 186801|Clostridia 1.0 C 1.0 Psort location Cytoplasmic, score 1.0 gap 1.0 - 1.0 1.2.1.12 1.0 ko:K00134 1.0 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 1.0 M00001,M00002,M00003,M00165,M00166,M00308,M00552 1.0 R01061 1.0 RC00149 1.0 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 1.0 - 1.0 - 1.0 - 1.0 Gp_dh_C,Gp_dh_N 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000038_02185 0.25 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating). triosephosphate dehydrogenase. Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate. D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho- glyceroyl phosphate + H(+) + NADH. 1.0 1.0 1.0 1.0 Glycolysis / Gluconeogenesis|Carbon fixation in photosynthetic organisms|Metabolic pathways|Biosynthesis of secondary metabolites|Microbial metabolism in diverse environments|Carbon metabolism|Biosynthesis of amino acids|HIF-1 signaling pathway|Alzheimer disease 1.0 K00134:GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1502480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +SLVDGHVIMPLPTYYGAN(Deamidated)GDGATHQSNEWITGK MGYG000000022_00233;MGYG000004679_00657 species d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C 1.0 COG1653@1|root,COG1653@2|Bacteria,1TR4M@1239|Firmicutes,24BFM@186801|Clostridia,3WJ7Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K02027,ko:K10192 1.0 ko02010,map02010 1.0 M00202,M00207 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1,3.A.1.1.11 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00233 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K02027:ABC.MS.S; multiple sugar transport system substrate-binding protein|K10192:togB; oligogalacturonide transport system substrate-binding protein 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 330963 0 0 0 0 1399475 0 0 0 0 318836 0 0 0 0 0 1347527 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1215878 0 0 0 0 0 0 0 0 0 1473692 0 0 0 0 0 695220 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 4530182 0 0 0 0 3069480 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 454423 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 18966554 0 0 0 0 243411 0 0 0 0 0 7201751 0 0 0 0 +TLIENNGTIDSIDEWGKR MGYG000000022_01085;MGYG000004679_00739 species d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C 1.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3WK85@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 J 1.0 Binds together with S18 to 16S ribosomal RNA 1.0 rpsF 1.0 - 1.0 - 1.0 ko:K02990 1.0 ko03010,map03010 1.0 M00178 1.0 - 1.0 - 1.0 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 1.0 - 1.0 - 1.0 - 1.0 Ribosomal_S6 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_01085 0.5 - - - - 1.0 1.0 1.0 1.0 Ribosome 1.0 K02990:RP-S6, MRPS6, rpsF; small subunit ribosomal protein S6 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 746164 0 0 0 0 462028 0 0 0 0 444629 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 948052 0 0 0 0 0 0 0 0 0 444045 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1426430 0 0 0 0 888729 0 0 0 0 1055571 0 0 0 0 0 0 0 0 0 0 +TTGNLDKDTEEALK MGYG000004679_00015;MGYG000000022_01422 species d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C 1.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit 1.0 atpA 1.0 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.0 3.6.3.14 1.0 ko:K02111 1.0 ko00190,ko00195,ko01100,map00190,map00195,map01100 1.0 M00157 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko00194,ko01000 1.0 3.A.2.1 1.0 - 1.0 - 1.0 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP 1.0 - 1.0 - 1.0 GT4 1.0 - 1.0 MGYG000004679_00015 0.5 H(+)-transporting two-sector ATPase. mitochondrial ATPase. A multisubunit non-phosphorylated ATPase that is involved in the transport of ions.-!-Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1).-!-The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases.-!-All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 alpha- and 3 beta-subunits) is connected via the delta-subunit to the membrane sector by several smaller subunits.-!-Within this complex, the gamma- and epsilon-subunits, as well as the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis.-!-This movement is driven by the H(+) electrochemical potential gradient.-!-The V-type (in vacuoles and clathrin-coated vesicles) and A-type (archaeal) enzymes have a similar structure but, under physiological conditions, they pump H(+) rather than synthesize ATP.-!-Formerly EC 3.6.1.34 and EC 3.6.3.14. ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate. 1.0 1.0 1.0 1.0 Oxidative phosphorylation|Photosynthesis|Metabolic pathways 1.0 K02111:ATPF1A, atpA; F-type H+/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 655425 0 0 0 0 585857 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1462352 0 0 0 0 0 0 0 0 0 1558678 0 0 0 0 0 0 0 0 0 0 +VC(Carbamidomethyl)KFDAIHIVDGVAK MGYG000000022_00023;MGYG000004679_00428 species d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C 1.0 COG1149@1|root,COG2878@1|root,COG1149@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,3WIFS@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 C 1.0 electron transport complex, RnfABCDGE type, B subunit 1.0 rnfB 1.0 - 1.0 - 1.0 ko:K03616 1.0 - 1.0 - 1.0 - 1.0 - 1.0 ko00000 1.0 - 1.0 - 1.0 - 1.0 FeS,Fer4,Fer4_13,Fer4_3,Fer4_4,Fer4_6,Fer4_7,Fer4_9 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00023 0.5 - - - - 1.0 1.0 1.0 1.0 - 1.0 K03616:rnfB; H+/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit B [EC:7.1.1.11 7.2.1.2] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 529292 0 0 0 0 495675 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 263045 0 0 0 0 0 0 0 0 0 87957 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 361892 0 0 0 0 592509 0 0 0 0 100655 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 834618 0 0 0 0 783555 0 0 0 0 574000 0 0 0 0 0 0 0 0 0 0 +VYELTAGKNPGE(Glu->Asp)VNIR MGYG000000333_01481;MGYG000003073_00897 species d__Bacteria|p__Actinobacteriota|c__Coriobacteriia|o__Coriobacteriales|f__Coriobacteriaceae|g__Collinsella|s__Collinsella sp002232035 1.0 COG2235@1|root,COG2235@2|Bacteria,2GJTR@201174|Actinobacteria,4CUZS@84998|Coriobacteriia 1.0 84998|Coriobacteriia 1.0 E 1.0 Arginine deiminase 1.0 arcA 1.0 - 1.0 3.5.3.6 1.0 ko:K01478 1.0 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 1.0 - 1.0 R00552 1.0 RC00177 1.0 ko00000,ko00001,ko01000 1.0 - 1.0 - 1.0 - 1.0 Amidinotransf 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000333_01481 0.5 arginine deiminase. arginine dihydrolase. Also acts on canavanine. H2O + L-arginine = L-citrulline + NH4(+). 1.0 1.0 1.0 1.0 Arginine biosynthesis|Metabolic pathways|Biosynthesis of secondary metabolites 1.0 K01478:arcA; arginine deiminase [EC:3.5.3.6] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2324140 0 2568372 0 0 0 2234872 0 0 0 0 0 0 0 0 0 0 2100692 0 0 0 0 0 0 0 0 0 3043193 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1785692 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2861803 0 0 0 0 0 0 0 0 0 0 4659421 0 0 0 0 2399718 0 0 0 0 0 0 2942990 0 0 0 0 0 0 0 0 0 2709039 0 0 0 0 +VPAEQYPEALQK MGYG000004679_00767;MGYG000000022_02299 species d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C 1.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3WGYV@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Galactose-1-phosphate uridyl transferase, C-terminal domain 1.0 galT 1.0 - 1.0 2.7.7.12 1.0 ko:K00965 1.0 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 1.0 M00362,M00554,M00632 1.0 R00955 1.0 RC00002 1.0 ko00000,ko00001,ko00002,ko01000 1.0 - 1.0 - 1.0 - 1.0 GalP_UDP_tr_C,GalP_UDP_transf 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000004679_00767 0.5 UDP-glucose--hexose-1-phosphate uridylyltransferase. uridylyl removing enzyme. - alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose. 1.0 1.0 1.0 1.0 Galactose metabolism|Amino sugar and nucleotide sugar metabolism|Metabolic pathways|Prolactin signaling pathway 1.0 K00965:galT, GALT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12] 1.0 none 1.0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 550589 0 0 0 0 571231 0 0 0 0 544166 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 692780 0 0 0 0 1180459 0 0 0 0 855953 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 262042 0 0 0 0 723726 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 +LGAC(Carbamidomethyl)NVANAQQC(Carbamidomethyl)VPISMTGR MGYG000000022_00233;MGYG000004679_00657 species d__Bacteria|p__Firmicutes_A|c__Clostridia|o__Oscillospirales|f__Ruminococcaceae|g__Faecalibacterium|s__Faecalibacterium prausnitzii_C 1.0 COG1653@1|root,COG1653@2|Bacteria,1TR4M@1239|Firmicutes,24BFM@186801|Clostridia,3WJ7Y@541000|Ruminococcaceae 1.0 186801|Clostridia 1.0 G 1.0 Bacterial extracellular solute-binding protein 1.0 - 1.0 - 1.0 - 1.0 ko:K02027,ko:K10192 1.0 ko02010,map02010 1.0 M00202,M00207 1.0 - 1.0 - 1.0 ko00000,ko00001,ko00002,ko02000 1.0 3.A.1.1,3.A.1.1.11 1.0 - 1.0 - 1.0 SBP_bac_1,SBP_bac_8,TAT_signal 1.0 - 1.0 - 1.0 - 1.0 - 1.0 MGYG000000022_00233 0.5 - - - - 1.0 1.0 1.0 1.0 ABC transporters 1.0 K02027:ABC.MS.S; multiple sugar transport system substrate-binding protein|K10192:togB; oligogalacturonide transport system substrate-binding protein 1.0 none 1.0 238148 0 0 0 0 0 0 0 0 0 0 0 0 0 0 339254 0 340761 0 0 0 0 350802 259787 0 0 0 420422 0 0 0 0 393943 0 0 0 0 0 1074976 114887 490331 744373 0 411139 289871 0 0 0 0 0 0 0 0 497230 0 4159366 483458 0 0 0 5104198 499224 908884 543229 0 4034257 504869 0 301351 0 453845 472004 0 133274 554715 545175 794668 592343 504952 421563 0 683587 803164 0 0 0 0 0 0 0 0 628806 0 2602120 449767 0 0 622278 3015620 857750 712124 922218 0 3242619 808199 0 678483 0 715835 551780 0 538488 572679 756399 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 275596 0 0 0 0 0 0 0 0 0 0 0 0 0 585950 1197106 1562387 1202389 0 1036965 1174950 0 0 0 0 0 0 0 0 954172 0 6168093 994442 0 0 701861 6810676 785736 1776025 704493 0 7150218 1643165 0 963240 0 1564173 1219747 0 1337387 746745 1205649 diff --git a/metax/peptide_annotator/pep_to_taxafunc.py b/metax/peptide_annotator/pep_to_taxafunc.py index f5a3159..a79b09a 100644 --- a/metax/peptide_annotator/pep_to_taxafunc.py +++ b/metax/peptide_annotator/pep_to_taxafunc.py @@ -48,6 +48,11 @@ # Date: 2024-07-14 # Version:0.2.11 # change it to a class for easy to use +# +# Date: 2024-08-21 +# Version:0.2.12 +# add the protein_id as a function to the output + from collections import Counter import sqlite3 @@ -164,6 +169,8 @@ def query_protein_from_db(self, protein_list): for v in re_dict.values(): # if the protein is not found in the database, return 'not_found' v.append('not_found') + # add the protein_id as a function + re_dict['protein_id'] = protein_list return re_dict @@ -218,13 +225,13 @@ def proteins_to_taxa_func(self,protein_list: list ) -> dict: import time t1 = time.time() - db_path = 'C:/Users/max/Desktop/MetaX_Suite/MetaX-human-gut-new.db' + db_path = 'C:/Users/Qing/Desktop/MetaX_Suite/metaX_dev_files/MetaX-human-gut_20231211.db' pep2taxafunc = Pep2TaxaFunc(db_path = db_path, threshold = 1, genome_mode = True) # for i in [pep_no_species_level, pep_null, pep2, pep7, pep8, pep9, pep10, pep11]: - for i in [pep3]: + for i in [pep2]: print(i) protein_list = i.split(';') # re = proteins_to_taxa_func(protein_list, threshold = 1, db_path='C:/Projects/pep2func/id2annotation.db') diff --git a/metax/utils/version.py b/metax/utils/version.py index 45b4501..ca3530f 100644 --- a/metax/utils/version.py +++ b/metax/utils/version.py @@ -1,2 +1,2 @@ -__version__ = '1.111.2' +__version__ = '1.111.3' API_version = '2' \ No newline at end of file diff --git a/pyproject.toml b/pyproject.toml index d240d3a..bb0362f 100644 --- a/pyproject.toml +++ b/pyproject.toml @@ -4,7 +4,7 @@ build-backend = "setuptools.build_meta" [project] name = "MetaXTools" -version = "1.111.2" +version = "1.111.3" description = "MetaXTools is a novel tool for linking peptide sequences with taxonomic and functional information in Metaproteomics." readme = "README_PyPi.md" license = { text = "NorthOmics" } From 851d9158ff611d382b7a98f3d4fd54666c1ae14c Mon Sep 17 00:00:00 2001 From: Qing <44231502+byemaxx@users.noreply.github.com> Date: Wed, 21 Aug 2024 12:47:33 -0400 Subject: [PATCH 5/7] - New: Added rotation option for the x-axis and y-axis of the heatmap plot. --- Docs/ChangeLog.md | 5 ++ metax/gui/main_gui.py | 9 ++- metax/gui/metax_gui/setting_window.ui | 77 ++++++++++++++++++----- metax/gui/metax_gui/settings_widget.py | 8 ++- metax/gui/metax_gui/ui_setting_window.py | 43 +++++++++---- metax/taxafunc_ploter/heatmap_plot.py | 79 +++++++++++++++++++----- metax/utils/version.py | 2 +- pyproject.toml | 2 +- 8 files changed, 177 insertions(+), 48 deletions(-) diff --git a/Docs/ChangeLog.md b/Docs/ChangeLog.md index 5b83d48..dfd8f56 100644 --- a/Docs/ChangeLog.md +++ b/Docs/ChangeLog.md @@ -1,3 +1,8 @@ +# Version: 1.111.4 +## Date: 2024-08-21 +### Changes: +- New: Added rotation option for the x-axis and y-axis of the heatmap plot. + # Version: 1.111.3 ## Date: 2024-08-21 ### Changes: diff --git a/metax/gui/main_gui.py b/metax/gui/main_gui.py index 438aaf0..18a2d98 100644 --- a/metax/gui/main_gui.py +++ b/metax/gui/main_gui.py @@ -207,8 +207,13 @@ def __init__(self, MainWindow): # ploting parameters # set the default theme mode self.html_theme = 'white' - - self.heatmap_params_dict = {'linkage_method': 'average', 'distance_metric': 'euclidean'} + + self.heatmap_params_dict = { + "linkage_method": "average", + "distance_metric": "euclidean", + "x_labels_rotation": 90, + "y_labels_rotation": 0, + } self.tf_link_net_params_dict = {'taxa_shape': 'circle', 'func_shape': 'rect', 'taxa_color': '#374E55','taxa_focus_color': '#6A6599', diff --git a/metax/gui/metax_gui/setting_window.ui b/metax/gui/metax_gui/setting_window.ui index 931b586..653cab3 100644 --- a/metax/gui/metax_gui/setting_window.ui +++ b/metax/gui/metax_gui/setting_window.ui @@ -17,7 +17,7 @@ - 0 + 1 @@ -586,22 +586,6 @@ - - - - - 0 - 0 - - - - Linkage Metric - - - Qt::AlignLeading|Qt::AlignLeft|Qt::AlignVCenter - - - @@ -654,6 +638,65 @@ + + + + + 0 + 0 + + + + Linkage Metric + + + Qt::AlignLeading|Qt::AlignLeft|Qt::AlignVCenter + + + + + + + X Labels Rotation + + + + + + + -90 + + + 90 + + + 15 + + + 90 + + + + + + + Y Labels Rotation + + + + + + + -90 + + + 90 + + + 15 + + + diff --git a/metax/gui/metax_gui/settings_widget.py b/metax/gui/metax_gui/settings_widget.py index 5cbe378..ba2b3cc 100644 --- a/metax/gui/metax_gui/settings_widget.py +++ b/metax/gui/metax_gui/settings_widget.py @@ -37,6 +37,8 @@ def __init__(self, parent=None, update_branch="main", auto_check_update=True, QS self.ui.comboBox_heatmap_linkage_method.currentTextChanged.connect(self.handle_heatmap_params_changed) self.ui.comboBox_heatmap_linkage_metric.currentTextChanged.connect(self.handle_heatmap_params_changed) + self.ui.spinBox_heatmap_x_labels_rotation.valueChanged.connect(self.handle_heatmap_params_changed) + self.ui.spinBox_heatmap_y_labels_rotation.valueChanged.connect(self.handle_heatmap_params_changed) # link all signal-slot connections for TF-link network @@ -85,10 +87,14 @@ def handle_checkbox_state_changed(self): def handle_heatmap_params_changed(self): method = self.ui.comboBox_heatmap_linkage_method.currentText() metric = self.ui.comboBox_heatmap_linkage_metric.currentText() + x_labels_rotation = self.ui.spinBox_heatmap_x_labels_rotation.value() + y_labels_rotation = self.ui.spinBox_heatmap_y_labels_rotation.value() heatmap_params_dict = { "linkage_method": method, - "distance_metric": metric + "distance_metric": metric, + "x_labels_rotation": x_labels_rotation, + "y_labels_rotation": y_labels_rotation, } self.heatmap_params_dict_changed.emit(heatmap_params_dict) diff --git a/metax/gui/metax_gui/ui_setting_window.py b/metax/gui/metax_gui/ui_setting_window.py index ad1cf70..245df5c 100644 --- a/metax/gui/metax_gui/ui_setting_window.py +++ b/metax/gui/metax_gui/ui_setting_window.py @@ -245,15 +245,6 @@ def setupUi(self, Settings): self.comboBox_heatmap_linkage_method.addItem("") self.comboBox_heatmap_linkage_method.addItem("") self.gridLayout_8.addWidget(self.comboBox_heatmap_linkage_method, 0, 1, 1, 1) - self.label_3 = QtWidgets.QLabel(self.page_2) - sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Fixed, QtWidgets.QSizePolicy.Preferred) - sizePolicy.setHorizontalStretch(0) - sizePolicy.setVerticalStretch(0) - sizePolicy.setHeightForWidth(self.label_3.sizePolicy().hasHeightForWidth()) - self.label_3.setSizePolicy(sizePolicy) - self.label_3.setAlignment(QtCore.Qt.AlignLeading|QtCore.Qt.AlignLeft|QtCore.Qt.AlignVCenter) - self.label_3.setObjectName("label_3") - self.gridLayout_8.addWidget(self.label_3, 0, 2, 1, 1) self.comboBox_heatmap_linkage_metric = QtWidgets.QComboBox(self.page_2) self.comboBox_heatmap_linkage_metric.setObjectName("comboBox_heatmap_linkage_metric") self.comboBox_heatmap_linkage_metric.addItem("") @@ -266,6 +257,34 @@ def setupUi(self, Settings): self.comboBox_heatmap_linkage_metric.addItem("") self.comboBox_heatmap_linkage_metric.addItem("") self.gridLayout_8.addWidget(self.comboBox_heatmap_linkage_metric, 0, 3, 1, 1) + self.label_3 = QtWidgets.QLabel(self.page_2) + sizePolicy = QtWidgets.QSizePolicy(QtWidgets.QSizePolicy.Fixed, QtWidgets.QSizePolicy.Preferred) + sizePolicy.setHorizontalStretch(0) + sizePolicy.setVerticalStretch(0) + sizePolicy.setHeightForWidth(self.label_3.sizePolicy().hasHeightForWidth()) + self.label_3.setSizePolicy(sizePolicy) + self.label_3.setAlignment(QtCore.Qt.AlignLeading|QtCore.Qt.AlignLeft|QtCore.Qt.AlignVCenter) + self.label_3.setObjectName("label_3") + self.gridLayout_8.addWidget(self.label_3, 0, 2, 1, 1) + self.label_25 = QtWidgets.QLabel(self.page_2) + self.label_25.setObjectName("label_25") + self.gridLayout_8.addWidget(self.label_25, 1, 0, 1, 1) + self.spinBox_heatmap_x_labels_rotation = QtWidgets.QSpinBox(self.page_2) + self.spinBox_heatmap_x_labels_rotation.setMinimum(-90) + self.spinBox_heatmap_x_labels_rotation.setMaximum(90) + self.spinBox_heatmap_x_labels_rotation.setSingleStep(15) + self.spinBox_heatmap_x_labels_rotation.setProperty("value", 90) + self.spinBox_heatmap_x_labels_rotation.setObjectName("spinBox_heatmap_x_labels_rotation") + self.gridLayout_8.addWidget(self.spinBox_heatmap_x_labels_rotation, 1, 1, 1, 1) + self.label_26 = QtWidgets.QLabel(self.page_2) + self.label_26.setObjectName("label_26") + self.gridLayout_8.addWidget(self.label_26, 1, 2, 1, 1) + self.spinBox_heatmap_y_labels_rotation = QtWidgets.QSpinBox(self.page_2) + self.spinBox_heatmap_y_labels_rotation.setMinimum(-90) + self.spinBox_heatmap_y_labels_rotation.setMaximum(90) + self.spinBox_heatmap_y_labels_rotation.setSingleStep(15) + self.spinBox_heatmap_y_labels_rotation.setObjectName("spinBox_heatmap_y_labels_rotation") + self.gridLayout_8.addWidget(self.spinBox_heatmap_y_labels_rotation, 1, 3, 1, 1) self.gridLayout_4.addLayout(self.gridLayout_8, 1, 3, 1, 1) self.label_20 = QtWidgets.QLabel(self.page_2) self.label_20.setObjectName("label_20") @@ -297,7 +316,7 @@ def setupUi(self, Settings): self.gridLayout.addWidget(self.toolBox, 0, 0, 1, 1) self.retranslateUi(Settings) - self.toolBox.setCurrentIndex(0) + self.toolBox.setCurrentIndex(1) QtCore.QMetaObject.connectSlotsByName(Settings) def retranslateUi(self, Settings): @@ -368,7 +387,6 @@ def retranslateUi(self, Settings): self.comboBox_heatmap_linkage_method.setItemText(4, _translate("Settings", "median")) self.comboBox_heatmap_linkage_method.setItemText(5, _translate("Settings", "weighted")) self.comboBox_heatmap_linkage_method.setItemText(6, _translate("Settings", "ward")) - self.label_3.setText(_translate("Settings", "Linkage Metric")) self.comboBox_heatmap_linkage_metric.setCurrentText(_translate("Settings", "euclidean")) self.comboBox_heatmap_linkage_metric.setItemText(0, _translate("Settings", "euclidean")) self.comboBox_heatmap_linkage_metric.setItemText(1, _translate("Settings", "chebyshev")) @@ -379,6 +397,9 @@ def retranslateUi(self, Settings): self.comboBox_heatmap_linkage_metric.setItemText(6, _translate("Settings", "rogerstanimoto")) self.comboBox_heatmap_linkage_metric.setItemText(7, _translate("Settings", "russellrao")) self.comboBox_heatmap_linkage_metric.setItemText(8, _translate("Settings", "sqeuclidean")) + self.label_3.setText(_translate("Settings", "Linkage Metric")) + self.label_25.setText(_translate("Settings", "X Labels Rotation")) + self.label_26.setText(_translate("Settings", "Y Labels Rotation")) self.label_20.setText(_translate("Settings", "Network Global")) self.label.setText(_translate("Settings", "HeatMap")) self.toolBox.setItemText(self.toolBox.indexOf(self.page_2), _translate("Settings", "Plotting")) diff --git a/metax/taxafunc_ploter/heatmap_plot.py b/metax/taxafunc_ploter/heatmap_plot.py index 7754caf..a47ba35 100644 --- a/metax/taxafunc_ploter/heatmap_plot.py +++ b/metax/taxafunc_ploter/heatmap_plot.py @@ -9,12 +9,16 @@ from .get_distinct_colors import GetDistinctColors class HeatmapPlot: - def __init__(self, tfobj, linkage_method:str = 'average', distance_metric:str = 'correlation'): + def __init__(self, tfobj, linkage_method:str = 'average', distance_metric:str = 'correlation', + x_labels_rotation:int = 90, y_labels_rotation:int = 0): self.tfa = tfobj self.get_distinct_colors = GetDistinctColors().get_distinct_colors self.assign_colors = GetDistinctColors().assign_colors self.linkage_method = linkage_method self.distance_metric = distance_metric + self.x_labels_rotation = x_labels_rotation + self.y_labels_rotation = y_labels_rotation + # input: df, func_name, top_number, value_type, fig_size # EXAMPLE: plot_top_taxa_func_heatmap_of_test_res(df_anova, sw.func, 200, 'f', (30,30)) @@ -145,12 +149,15 @@ def plot_top_taxa_func_heatmap_of_test_res(self, df, top_number:int|str= 100, fig.ax_heatmap.set_xticklabels( fig.ax_heatmap.get_xmajorticklabels(), fontsize=font_size, - rotation=90, + rotation=self.x_labels_rotation, + ha = 'right' if self.x_labels_rotation > 0 else 'left' ) fig.ax_heatmap.set_yticklabels( fig.ax_heatmap.get_ymajorticklabels(), fontsize=font_size, - rotation=0, + rotation=self.y_labels_rotation, + ha = 'left', + va = 'baseline' if self.y_labels_rotation > 0 else 'top' ) cbar = fig.ax_heatmap.collections[0].colorbar @@ -284,10 +291,21 @@ def plot_basic_heatmap_of_test_res(self, df, top_number:int = 100, value_type:st return sorted_df - # plot heatmap figure - fig.ax_heatmap.set_xticklabels(fig.ax_heatmap.get_xmajorticklabels(), fontsize=font_size, rotation=90) - fig.ax_heatmap.set_yticklabels(fig.ax_heatmap.get_ymajorticklabels(), fontsize=font_size, rotation=0) - + # plot heatmap figure + fig.ax_heatmap.set_xticklabels( + fig.ax_heatmap.get_xmajorticklabels(), + fontsize=font_size, + rotation=self.x_labels_rotation, + ha = 'right' if self.x_labels_rotation > 0 else 'left' + ) + fig.ax_heatmap.set_yticklabels( + fig.ax_heatmap.get_ymajorticklabels(), + fontsize=font_size, + rotation=self.y_labels_rotation, + ha = 'left', + va = 'baseline' if self.y_labels_rotation > 0 else 'top' + ) + scale_title = f", scaled by {scale}" if scale in ['row', 'column', 'all'] else '' plt.suptitle( f"The Heatmap of intensity of Significant differences between groups (top {top_number} sorted by {sort_by.split('(')[0]}{scale_title})" @@ -373,11 +391,20 @@ def plot_basic_heatmap(self, df, title = 'Heatmap',fig_size:tuple|None = None, "yticklabels": True if show_all_labels[1] else "auto", } fig = sns.clustermap(mat, **sns_params) - - - fig.ax_heatmap.set_xticklabels(fig.ax_heatmap.get_xmajorticklabels(), fontsize=font_size, rotation=90) - fig.ax_heatmap.set_yticklabels(fig.ax_heatmap.get_ymajorticklabels(), fontsize=font_size, rotation=0) + fig.ax_heatmap.set_xticklabels( + fig.ax_heatmap.get_xmajorticklabels(), + fontsize=font_size, + rotation=self.x_labels_rotation, + ha="right" if self.x_labels_rotation > 0 else "left", + ) + fig.ax_heatmap.set_yticklabels( + fig.ax_heatmap.get_ymajorticklabels(), + fontsize=font_size, + rotation=self.y_labels_rotation, + ha="left", + va="baseline" if self.y_labels_rotation > 0 else "top", + ) title = f"{title} (scaled by {scale})" if scale not in [None, 'None'] else title plt.suptitle(title, weight='bold') @@ -525,8 +552,19 @@ def plot_heatmap_of_all_condition_res(self, df, pvalue:float = 0.05,scale:str|N if return_type == 'fig': fig = sns.clustermap(dft, **sns_params) - fig.ax_heatmap.set_xticklabels(fig.ax_heatmap.get_xmajorticklabels(), fontsize=font_size, rotation=90) - fig.ax_heatmap.set_yticklabels(fig.ax_heatmap.get_ymajorticklabels(), fontsize=font_size, rotation=0) + fig.ax_heatmap.set_xticklabels( + fig.ax_heatmap.get_xmajorticklabels(), + fontsize=font_size, + rotation=self.x_labels_rotation, + ha = 'right' if self.x_labels_rotation > 0 else 'left' + ) + fig.ax_heatmap.set_yticklabels( + fig.ax_heatmap.get_ymajorticklabels(), + fontsize=font_size, + rotation=self.y_labels_rotation, + ha = 'left', + va = 'baseline' if self.y_labels_rotation > 0 else 'top' + ) if res_df_type == 'deseq2': title = f"The Heatmap of log2FoldChange calculated by DESeq2 ({p_type} <= {pvalue}, {log2fc_min} <= log2fc <= {log2fc_max}, scaled by {scale})" else: @@ -652,8 +690,19 @@ def plot_heatmap_of_dunnett_test_res(self, df, pvalue:float = 0.05,scale:str|No } fig = sns.clustermap(dft, **sns_params) - fig.ax_heatmap.set_xticklabels(fig.ax_heatmap.get_xmajorticklabels(), fontsize=font_size, rotation=90) - fig.ax_heatmap.set_yticklabels(fig.ax_heatmap.get_ymajorticklabels(), fontsize=font_size, rotation=0) + fig.ax_heatmap.set_xticklabels( + fig.ax_heatmap.get_xmajorticklabels(), + fontsize=font_size, + rotation=self.x_labels_rotation, + ha = 'right' if self.x_labels_rotation > 0 else 'left' + ) + fig.ax_heatmap.set_yticklabels( + fig.ax_heatmap.get_ymajorticklabels(), + fontsize=font_size, + rotation=self.y_labels_rotation, + ha = 'left', + va = 'baseline' if self.y_labels_rotation > 0 else 'top' + ) plt.suptitle(f"The Heatmap of t-statistic calculated by Dunnett test (p-value < {pvalue}, scaled by {scale})", weight='bold') diff --git a/metax/utils/version.py b/metax/utils/version.py index ca3530f..8885c27 100644 --- a/metax/utils/version.py +++ b/metax/utils/version.py @@ -1,2 +1,2 @@ -__version__ = '1.111.3' +__version__ = '1.111.4' API_version = '2' \ No newline at end of file diff --git a/pyproject.toml b/pyproject.toml index bb0362f..d1fc40b 100644 --- a/pyproject.toml +++ b/pyproject.toml @@ -4,7 +4,7 @@ build-backend = "setuptools.build_meta" [project] name = "MetaXTools" -version = "1.111.3" +version = "1.111.4" description = "MetaXTools is a novel tool for linking peptide sequences with taxonomic and functional information in Metaproteomics." readme = "README_PyPi.md" license = { text = "NorthOmics" } From 4e3b361cdf574dde7b72e8449d8f14f6c68e15c8 Mon Sep 17 00:00:00 2001 From: Qing <44231502+byemaxx@users.noreply.github.com> Date: Wed, 21 Aug 2024 14:21:49 -0400 Subject: [PATCH 6/7] - Change: Optimized the x-axis and y-axis labels of the heatmap plot to make the labels more clear. --- Docs/ChangeLog.md | 6 +++++ metax/taxafunc_ploter/heatmap_plot.py | 35 +++++++++++++++++++-------- metax/utils/version.py | 2 +- pyproject.toml | 2 +- 4 files changed, 33 insertions(+), 12 deletions(-) diff --git a/Docs/ChangeLog.md b/Docs/ChangeLog.md index dfd8f56..bfe5f69 100644 --- a/Docs/ChangeLog.md +++ b/Docs/ChangeLog.md @@ -1,3 +1,9 @@ +# Version: 1.111.5 +## Date: 2024-08-21 +### Changes: +- Change: Optimized the x-axis and y-axis labels of the heatmap plot to make the labels more clear. + + # Version: 1.111.4 ## Date: 2024-08-21 ### Changes: diff --git a/metax/taxafunc_ploter/heatmap_plot.py b/metax/taxafunc_ploter/heatmap_plot.py index a47ba35..cf5c5b2 100644 --- a/metax/taxafunc_ploter/heatmap_plot.py +++ b/metax/taxafunc_ploter/heatmap_plot.py @@ -25,6 +25,21 @@ def __init__(self, tfobj, linkage_method:str = 'average', distance_metric:str = # reset sns style sns.set_theme() plt.style.use('default') + + def get_x_labels_ha(self): + x_rotation = self.x_labels_rotation + if x_rotation > 0: + return 'right' + elif x_rotation < 0: + return 'left' + else: + return 'center' + def get_y_labels_va(self): + y_rotation = self.y_labels_rotation + if y_rotation >= 0: + return 'baseline' + else: + return 'top' def rename_taxa(self, df): first_index = df.index[0] @@ -150,14 +165,14 @@ def plot_top_taxa_func_heatmap_of_test_res(self, df, top_number:int|str= 100, fig.ax_heatmap.get_xmajorticklabels(), fontsize=font_size, rotation=self.x_labels_rotation, - ha = 'right' if self.x_labels_rotation > 0 else 'left' + ha = self.get_x_labels_ha() ) fig.ax_heatmap.set_yticklabels( fig.ax_heatmap.get_ymajorticklabels(), fontsize=font_size, rotation=self.y_labels_rotation, ha = 'left', - va = 'baseline' if self.y_labels_rotation > 0 else 'top' + va = self.get_y_labels_va() ) cbar = fig.ax_heatmap.collections[0].colorbar @@ -296,14 +311,14 @@ def plot_basic_heatmap_of_test_res(self, df, top_number:int = 100, value_type:st fig.ax_heatmap.get_xmajorticklabels(), fontsize=font_size, rotation=self.x_labels_rotation, - ha = 'right' if self.x_labels_rotation > 0 else 'left' + ha = self.get_x_labels_ha() ) fig.ax_heatmap.set_yticklabels( fig.ax_heatmap.get_ymajorticklabels(), fontsize=font_size, rotation=self.y_labels_rotation, ha = 'left', - va = 'baseline' if self.y_labels_rotation > 0 else 'top' + va = self.get_y_labels_va() ) scale_title = f", scaled by {scale}" if scale in ['row', 'column', 'all'] else '' @@ -396,14 +411,14 @@ def plot_basic_heatmap(self, df, title = 'Heatmap',fig_size:tuple|None = None, fig.ax_heatmap.get_xmajorticklabels(), fontsize=font_size, rotation=self.x_labels_rotation, - ha="right" if self.x_labels_rotation > 0 else "left", + ha=self.get_x_labels_ha() ) fig.ax_heatmap.set_yticklabels( fig.ax_heatmap.get_ymajorticklabels(), fontsize=font_size, rotation=self.y_labels_rotation, ha="left", - va="baseline" if self.y_labels_rotation > 0 else "top", + va=self.get_y_labels_va() ) title = f"{title} (scaled by {scale})" if scale not in [None, 'None'] else title plt.suptitle(title, weight='bold') @@ -556,14 +571,14 @@ def plot_heatmap_of_all_condition_res(self, df, pvalue:float = 0.05,scale:str|N fig.ax_heatmap.get_xmajorticklabels(), fontsize=font_size, rotation=self.x_labels_rotation, - ha = 'right' if self.x_labels_rotation > 0 else 'left' + ha = self.get_x_labels_ha() ) fig.ax_heatmap.set_yticklabels( fig.ax_heatmap.get_ymajorticklabels(), fontsize=font_size, rotation=self.y_labels_rotation, ha = 'left', - va = 'baseline' if self.y_labels_rotation > 0 else 'top' + va = self.get_y_labels_va() ) if res_df_type == 'deseq2': title = f"The Heatmap of log2FoldChange calculated by DESeq2 ({p_type} <= {pvalue}, {log2fc_min} <= log2fc <= {log2fc_max}, scaled by {scale})" @@ -694,14 +709,14 @@ def plot_heatmap_of_dunnett_test_res(self, df, pvalue:float = 0.05,scale:str|No fig.ax_heatmap.get_xmajorticklabels(), fontsize=font_size, rotation=self.x_labels_rotation, - ha = 'right' if self.x_labels_rotation > 0 else 'left' + ha = self.get_x_labels_ha() ) fig.ax_heatmap.set_yticklabels( fig.ax_heatmap.get_ymajorticklabels(), fontsize=font_size, rotation=self.y_labels_rotation, ha = 'left', - va = 'baseline' if self.y_labels_rotation > 0 else 'top' + va = self.get_y_labels_va() ) plt.suptitle(f"The Heatmap of t-statistic calculated by Dunnett test (p-value < {pvalue}, scaled by {scale})", weight='bold') diff --git a/metax/utils/version.py b/metax/utils/version.py index 8885c27..89c504f 100644 --- a/metax/utils/version.py +++ b/metax/utils/version.py @@ -1,2 +1,2 @@ -__version__ = '1.111.4' +__version__ = '1.111.5' API_version = '2' \ No newline at end of file diff --git a/pyproject.toml b/pyproject.toml index d1fc40b..2eeba7f 100644 --- a/pyproject.toml +++ b/pyproject.toml @@ -4,7 +4,7 @@ build-backend = "setuptools.build_meta" [project] name = "MetaXTools" -version = "1.111.4" +version = "1.111.5" description = "MetaXTools is a novel tool for linking peptide sequences with taxonomic and functional information in Metaproteomics." readme = "README_PyPi.md" license = { text = "NorthOmics" } From 5dfc08bdfa7d4dab11ce04f8029657c918249e64 Mon Sep 17 00:00:00 2001 From: Qing Date: Wed, 21 Aug 2024 23:44:51 -0400 Subject: [PATCH 7/7] - Fix: Fixed the bug of extrcting the peptides of taxa, funcs or taxa-funcs, when split the function items. --- Docs/ChangeLog.md | 7 +- metax/gui/main_gui.py | 27 +++---- metax/taxafunc_analyzer/analyzer.py | 75 ++++++++++++++++++- .../analyzer_utils/get_matrix.py | 15 ++-- metax/utils/version.py | 2 +- pyproject.toml | 2 +- 6 files changed, 98 insertions(+), 30 deletions(-) diff --git a/Docs/ChangeLog.md b/Docs/ChangeLog.md index bfe5f69..a519131 100644 --- a/Docs/ChangeLog.md +++ b/Docs/ChangeLog.md @@ -1,9 +1,14 @@ +# Version: 1.111.6 +## Date: 2024-08-21 +### Changes: +- Fix: Fixed the bug of extrcting the peptides of taxa, funcs or taxa-funcs, when split the function items. + + # Version: 1.111.5 ## Date: 2024-08-21 ### Changes: - Change: Optimized the x-axis and y-axis labels of the heatmap plot to make the labels more clear. - # Version: 1.111.4 ## Date: 2024-08-21 ### Changes: diff --git a/metax/gui/main_gui.py b/metax/gui/main_gui.py index 18a2d98..5bfde74 100644 --- a/metax/gui/main_gui.py +++ b/metax/gui/main_gui.py @@ -3479,28 +3479,19 @@ def plot_basic_list(self, plot_type='heatmap'): df = self.tfa.peptide_df.copy() else: + peptides_list = [] + if table_name == 'Taxa': - df = self.tfa.clean_df.loc[self.tfa.clean_df['Taxon'].isin(self.basic_heatmap_list)] - df.index = df[self.tfa.peptide_col_name] + for i in self.basic_heatmap_list: + peptides_list.extend(self.tfa.peptides_linked_dict['taxa'][i]) elif table_name == 'Functions': - df = self.tfa.clean_df.loc[self.tfa.clean_df[self.tfa.func_name].isin(self.basic_heatmap_list)] - df.index = df[self.tfa.peptide_col_name] + for i in self.basic_heatmap_list: + peptides_list.extend(self.tfa.peptides_linked_dict['func'][i]) elif table_name == 'Taxa-Functions': - df_list = [] for i in self.basic_heatmap_list: - taxon, func = i.split(' <') - func = func[:-1] - dft = self.tfa.clean_df.loc[(self.tfa.clean_df['Taxon'] == taxon) & (self.tfa.clean_df[self.tfa.func_name] == func)] - df_list.append(dft) - - if df_list: - df_all = pd.concat(df_list) - df_all.index = df_all[self.tfa.peptide_col_name] - df = df_all - else: - raise ValueError('No valid taxa-function belongs to the selected taxa-function!') + peptides_list.extend(self.tfa.peptides_linked_dict['taxa_func'][i]) elif table_name == 'Proteins': QMessageBox.warning(self.MainWindow, 'Warning', @@ -3511,9 +3502,9 @@ def plot_basic_list(self, plot_type='heatmap'): return else: # Peptide - df = self.tfa.peptide_df.copy() - df = df.loc[self.basic_heatmap_list] + peptides_list = self.basic_heatmap_list + df = self.tfa.peptide_df.loc[peptides_list] df = df[sample_list] else: diff --git a/metax/taxafunc_analyzer/analyzer.py b/metax/taxafunc_analyzer/analyzer.py index 4c8ddbd..2707a05 100644 --- a/metax/taxafunc_analyzer/analyzer.py +++ b/metax/taxafunc_analyzer/analyzer.py @@ -70,11 +70,15 @@ def __init__( self.func_taxa_df: Optional[pd.DataFrame] = None self.taxa_func_linked_dict: Optional[Dict[str, List[tuple]]] = None self.func_taxa_linked_dict: Optional[Dict[str, List[tuple]]] = None + self.peptides_linked_dict = {'taxa': {}, 'func': {}, 'taxa_func': {}} self.protein_df: Optional[pd.DataFrame] = None self.any_df_mode = any_df_mode # if True, the consider the TaxaFunc df as other_df self.custom_df: Optional[pd.DataFrame] = None # other df, any df that user want to add self.outlier_status = {'peptide': None, 'taxa': None, 'func': None, 'taxa_func': None, 'protein': None, 'custom': None} + + self.split_func_status:bool = False + self.split_func_sep:str = '' # load function self.BasicStats = BasicStats(self) @@ -560,6 +564,7 @@ def split_func(self, taxa_func_df, split_func_params: dict = {'split_by': ',', ' num_splits = len(split_funcs_list) for new_func in split_funcs_list: + new_func = new_func.strip() split_row = row[sample_list] / num_splits if share_intensity else row[sample_list] split_row[func_col] = new_func split_row[taxon_col] = row[taxon_col] @@ -577,6 +582,65 @@ def split_func(self, taxa_func_df, split_func_params: dict = {'split_by': ',', ' return new_data + def create_peptides_dict_in_taxa_func(self, dfc): + """ + Creates a dictionary of peptides in taxa, func, and taxa_func. + Parameters: + dfc (DataFrame): The input DataFrame containing the peptide, taxon, and function columns. + Returns: + self.peptides_linked_dict (dict): A dictionary containing the peptides in taxa, func, and taxa_func. + """ + print("Creating peptides_linked_dict in taxa, func, and taxa_func...") + df = dfc.copy()[[self.peptide_col_name, 'Taxon', self.func_name]] + peptide_col = self.peptide_col_name + taxa_col = 'Taxon' + func_col = self.func_name + + peptides_in_taxa_func = {} + peptides_in_taxa = {} + peptides_in_func = {} + + if self.split_func_status: + for _, row in tqdm(df.iterrows(), total=len(df), desc="Creating peptides_dict"): + peptide = row[peptide_col] + taxa = row[taxa_col] + func_list = [f.strip() for f in row[func_col].split(self.split_func_sep)] + + if taxa not in peptides_in_taxa: + peptides_in_taxa[taxa] = [] + peptides_in_taxa[taxa].append(peptide) + + for f in func_list: + if f not in peptides_in_func: + peptides_in_func[f] = [] + peptides_in_func[f].append(peptide) + taxa_func = f'{taxa} <{f}>' + if taxa_func not in peptides_in_taxa_func: + peptides_in_taxa_func[taxa_func] = [] + peptides_in_taxa_func[taxa_func].append(peptide) + else: + for _, row in tqdm(df.iterrows(), total=len(df), desc="Creating peptides_dict"): + peptide = row[peptide_col] + taxa = row[taxa_col] + func = row[func_col] + + if taxa not in peptides_in_taxa: + peptides_in_taxa[taxa] = [] + peptides_in_taxa[taxa].append(peptide) + + if func not in peptides_in_func: + peptides_in_func[func] = [] + peptides_in_func[func].append(peptide) + + taxa_func = f'{taxa} <{func}>' + if taxa_func not in peptides_in_taxa_func: + peptides_in_taxa_func[taxa_func] = [] + peptides_in_taxa_func[taxa_func].append(peptide) + + + self.peptides_linked_dict = {'taxa': peptides_in_taxa, 'func': peptides_in_func, 'taxa_func': peptides_in_taxa_func} + return self.peptides_linked_dict + def set_multi_tables(self, level: str = 's', func_threshold:float = 1.00, processing_after_sum: bool = False, @@ -615,7 +679,10 @@ def set_multi_tables(self, level: str = 's', func_threshold:float = 1.00, #! fllowing code is for the normal mode # reset outlier_status self.outlier_status = {'peptide': None, 'taxa': None, 'func': None, 'taxa_func': None} - + # reset split_func status + self.split_func_status = split_func + self.split_func_sep = split_func_params['split_by'] + df = self.original_df.copy() # perform data pre-processing if not processing_after_sum: @@ -727,7 +794,9 @@ def strip_taxa(x, level): df_taxa = df_taxa[df_taxa['peptide_num'] >= peptide_num_threshold['taxa']] print(f"Taxa number with '{level}' level, peptide_num >= [{peptide_num_threshold['taxa']}]: {df_taxa.shape[0]}") #-----Taxa Table End----- - + + #------create peptides_dict in taxa, func and taxa_func------ + self.create_peptides_dict_in_taxa_func(dfc) # ----- create taxa_func table ----- df_taxa_func = dfc.copy() @@ -879,7 +948,7 @@ def get_df(self, table_name:str = 'taxa'): 'processing_order': None}, peptide_num_threshold = {'taxa': 1, 'func': 1, 'taxa_func': 1}, keep_unknow_func=False, sum_protein=False, sum_protein_params = {'method': 'razor', 'by_sample': False, 'rank_method': 'unique_counts', 'greedy_method': 'heap'}, - split_func=True, split_func_params = {'split_by': ';', 'share_intensity': False} + split_func=True, split_func_params = {'split_by': '|', 'share_intensity': False} ) sw.check_attributes() \ No newline at end of file diff --git a/metax/taxafunc_analyzer/analyzer_utils/get_matrix.py b/metax/taxafunc_analyzer/analyzer_utils/get_matrix.py index 01c77c4..acd6ead 100644 --- a/metax/taxafunc_analyzer/analyzer_utils/get_matrix.py +++ b/metax/taxafunc_analyzer/analyzer_utils/get_matrix.py @@ -4,8 +4,8 @@ class GetMatrix: def __init__(self, tfa): self.tfa = tfa - def get_intensity_matrix(self, func_name: str = None, taxon_name: str = None, - peptide_seq: str = None, sample_list: list = None, condition:list = None) -> pd.DataFrame: + def get_intensity_matrix(self, func_name: str|None = None, taxon_name: str|None = None, + peptide_seq: str|None = None, sample_list: list|None = None, condition:list|None = None) -> pd.DataFrame: # input: a taxon with its function, a function with its taxon, # and the peptides in the function or taxon # output: a matrix of the intensity of the taxon or function or peptide in each sample @@ -21,10 +21,13 @@ def get_intensity_matrix(self, func_name: str = None, taxon_name: str = None, if taxon_name is None: dft = dft[dft[self.tfa.func_name] == func_name] dft.set_index('Taxon', inplace=True) - if taxon_name is not None: - dft = self.tfa.clean_df[(self.tfa.clean_df['Taxon'] == taxon_name) & ( - self.tfa.clean_df[self.tfa.func_name] == func_name)] - dft.set_index(self.tfa.peptide_col_name, inplace=True) + + if taxon_name is not None: #all peptides in the taxon-function + # get the intensity matrix of the taxon with its function + taxa_func = f'{taxon_name} <{func_name}>' + peptides_list = self.tfa.peptides_linked_dict['taxa_func'][taxa_func] + dft = self.tfa.peptide_df.loc[peptides_list] + elif taxon_name is not None and peptide_seq is None: dft = self.tfa.func_taxa_df.copy() diff --git a/metax/utils/version.py b/metax/utils/version.py index 89c504f..7225fd1 100644 --- a/metax/utils/version.py +++ b/metax/utils/version.py @@ -1,2 +1,2 @@ -__version__ = '1.111.5' +__version__ = '1.111.6' API_version = '2' \ No newline at end of file diff --git a/pyproject.toml b/pyproject.toml index 2eeba7f..ea0a2f9 100644 --- a/pyproject.toml +++ b/pyproject.toml @@ -4,7 +4,7 @@ build-backend = "setuptools.build_meta" [project] name = "MetaXTools" -version = "1.111.5" +version = "1.111.6" description = "MetaXTools is a novel tool for linking peptide sequences with taxonomic and functional information in Metaproteomics." readme = "README_PyPi.md" license = { text = "NorthOmics" }